-- dump date 20140619_081634 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 595496000001 SEQ_END SEQ_END NC_012759.1 4578159 4578159 DR NC_012759.1; contig end 4578159..4578159 Escherichia coli BW2952 YP_002925203.1 CDS thrL NC_012759.1 190 255 D involved in threonine biosynthesis; controls the expression of the thrLABC operon; thr operon leader peptide 190..255 Escherichia coli BW2952 7956300 YP_002925204.1 CDS thrA NC_012759.1 337 2799 D multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 337..2799 Escherichia coli BW2952 7956140 YP_002925205.1 CDS thrB NC_012759.1 2801 3733 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 2801..3733 Escherichia coli BW2952 7953657 YP_002925206.1 CDS thrC NC_012759.1 3734 5020 D catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 3734..5020 Escherichia coli BW2952 7953919 YP_002925207.1 CDS yaaX NC_012759.1 5234 5530 D MG1655 equivalent: b0005; hypothetical protein 5234..5530 Escherichia coli BW2952 7956146 YP_002925208.1 CDS yaaA NC_012759.1 5683 6459 R MG1655 equivalent: b0006; hypothetical protein complement(5683..6459) Escherichia coli BW2952 7955438 YP_002925209.1 CDS yaaJ NC_012759.1 6529 7959 R MG1655 equivalent: b0007; putative transporter complement(6529..7959) Escherichia coli BW2952 7952753 YP_002925210.1 CDS talB NC_012759.1 8238 9191 D MG1655 equivalent: b0008; transaldolase B 8238..9191 Escherichia coli BW2952 7955646 YP_002925211.1 CDS mogA NC_012759.1 9306 9893 D forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 9306..9893 Escherichia coli BW2952 7956165 YP_002925212.1 CDS yaaH NC_012759.1 9928 10494 R MG1655 equivalent: b0010; hypothetical protein complement(9928..10494) Escherichia coli BW2952 7955164 YP_002925213.1 CDS yaaW NC_012759.1 10643 11356 R MG1655 equivalent: b0011; hypothetical protein complement(10643..11356) Escherichia coli BW2952 7952740 YP_002925214.1 CDS yaaI NC_012759.1 11382 11786 R MG1655 equivalent: b0013; hypothetical protein complement(11382..11786) Escherichia coli BW2952 7952754 YP_002925215.1 CDS dnaK NC_012759.1 12163 14079 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 12163..14079 Escherichia coli BW2952 7955333 YP_002925216.1 CDS dnaJ NC_012759.1 14168 15298 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 14168..15298 Escherichia coli BW2952 7952628 YP_002925217.1 CDS insL NC_012759.1 15445 16557 D MG1655 equivalent: b0016; IS186/IS421 transposase 15445..16557 Escherichia coli BW2952 7952627 YP_002925218.1 CDS mokC NC_012759.1 16751 16960 R MG1655 equivalent: b0018; regulatory protein for HokC, overlaps CDS of hokC complement(16751..16960) Escherichia coli BW2952 7954025 YP_002925219.1 CDS hokC NC_012759.1 16751 16903 R MG1655 equivalent: b4412; toxic membrane protein, small complement(16751..16903) Escherichia coli BW2952 7955932 YP_002925220.1 CDS nhaA NC_012759.1 17489 18655 D exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 17489..18655 Escherichia coli BW2952 7952167 YP_002925221.1 CDS nhaR NC_012759.1 18715 19620 D Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 18715..19620 Escherichia coli BW2952 7956057 YP_002925222.1 CDS insB NC_012759.1 19811 20314 R MG1655 equivalent: b0021; IS1 transposase InsAB' complement(19811..20314) Escherichia coli BW2952 7953375 YP_002925223.1 CDS insA NC_012759.1 20233 20508 R MG1655 equivalent: b0022; KpLE2 phage-like element; IS1 repressor protein InsA complement(20233..20508) Escherichia coli BW2952 7954020 YP_002925224.1 CDS rpsT NC_012759.1 20815 21078 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(20815..21078) Escherichia coli BW2952 7954067 YP_002925225.1 CDS yaaY NC_012759.1 21181 21399 D MG1655 equivalent: b0024; hypothetical protein 21181..21399 Escherichia coli BW2952 7952284 YP_002925226.1 CDS ribF NC_012759.1 21407 22348 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 21407..22348 Escherichia coli BW2952 7955439 YP_002925227.1 CDS ileS NC_012759.1 22391 25207 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 22391..25207 Escherichia coli BW2952 7952573 YP_002925228.1 CDS lspA NC_012759.1 25207 25701 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 25207..25701 Escherichia coli BW2952 7954053 YP_002925229.1 CDS fkpB NC_012759.1 25826 26275 D MG1655 equivalent: b0028; FKBP-type peptidyl-prolyl cis-trans isomerase 25826..26275 Escherichia coli BW2952 7955771 YP_002925230.1 CDS ispH NC_012759.1 26277 27227 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 26277..27227 Escherichia coli BW2952 7953580 YP_002925231.1 CDS rihC NC_012759.1 27293 28207 D catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC 27293..28207 Escherichia coli BW2952 7952229 YP_002925232.1 CDS dapB NC_012759.1 28374 29195 D catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 28374..29195 Escherichia coli BW2952 7955968 YP_002925233.1 CDS carA NC_012759.1 29651 30799 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 29651..30799 Escherichia coli BW2952 7953249 YP_002925234.1 CDS carB NC_012759.1 30817 34038 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 30817..34038 Escherichia coli BW2952 7952593 YP_002925235.1 CDS caiF NC_012759.1 34300 34695 D regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 34300..34695 Escherichia coli BW2952 7952594 YP_002925236.1 CDS caiE NC_012759.1 34781 35371 R involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE complement(34781..35371) Escherichia coli BW2952 7953376 YP_002925237.1 CDS caiD NC_012759.1 35377 36270 R catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase complement(35377..36270) Escherichia coli BW2952 7954605 YP_002925238.1 CDS caiC NC_012759.1 36271 37839 R MG1655 equivalent: b0037; putative crotonobetaine/carnitine-CoA ligase complement(36271..37839) Escherichia coli BW2952 7953163 YP_002925239.1 CDS caiB NC_012759.1 37898 39115 R catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase complement(37898..39115) Escherichia coli BW2952 7954701 YP_002925240.1 CDS caiA NC_012759.1 39244 40386 R catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase complement(39244..40386) Escherichia coli BW2952 7953164 YP_002925241.1 CDS caiT NC_012759.1 40417 41931 R catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter complement(40417..41931) Escherichia coli BW2952 7953162 YP_002925242.1 CDS fixA NC_012759.1 42403 43173 D required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; putative electron transfer flavoprotein FixA 42403..43173 Escherichia coli BW2952 7955647 YP_002925243.1 CDS fixB NC_012759.1 43188 44129 D involved in electron transfer during carnitine metabolism; putative electron transfer flavoprotein FixB 43188..44129 Escherichia coli BW2952 7954829 YP_002925244.1 CDS fixC NC_012759.1 44180 45466 D FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; putative oxidoreductase FixC 44180..45466 Escherichia coli BW2952 7954831 YP_002925245.1 CDS fixX NC_012759.1 45463 45750 D MG1655 equivalent: b0044; putative 4Fe-4S ferredoxin-type protein 45463..45750 Escherichia coli BW2952 7955241 YP_002925246.1 CDS yaaU NC_012759.1 45807 47138 D MG1655 equivalent: b0045; putative transporter 45807..47138 Escherichia coli BW2952 7954592 YP_002925247.1 CDS kefF NC_012759.1 47246 47776 D Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 47246..47776 Escherichia coli BW2952 7955677 YP_002925248.1 CDS kefC NC_012759.1 47769 49631 D transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 47769..49631 Escherichia coli BW2952 7953611 YP_002925249.1 CDS folA NC_012759.1 49823 50302 D catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 49823..50302 Escherichia coli BW2952 7954579 YP_002925250.1 CDS apaH NC_012759.1 50380 51222 R hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase complement(50380..51222) Escherichia coli BW2952 7953251 YP_002925251.1 CDS apaG NC_012759.1 51229 51606 R protein associated with Co2+ and Mg2+ efflux; ApaG protein complement(51229..51606) Escherichia coli BW2952 7953246 YP_002925252.1 CDS ksgA NC_012759.1 51609 52430 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(51609..52430) Escherichia coli BW2952 7955782 YP_002925253.1 CDS pdxA NC_012759.1 52427 53416 R catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase complement(52427..53416) Escherichia coli BW2952 7956000 YP_002925254.1 CDS surA NC_012759.1 53416 54702 R Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA complement(53416..54702) Escherichia coli BW2952 7952333 YP_002925255.1 CDS imp NC_012759.1 54755 57109 R determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein complement(54755..57109) Escherichia coli BW2952 7954480 YP_002925256.1 CDS djlA NC_012759.1 57364 58179 D functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 57364..58179 Escherichia coli BW2952 7953551 YP_002925257.1 CDS rluA NC_012759.1 59687 60346 R catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A complement(59687..60346) Escherichia coli BW2952 7953489 YP_002925258.1 CDS hepA NC_012759.1 60358 63264 R transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA complement(60358..63264) Escherichia coli BW2952 7955820 YP_002925259.1 CDS polB NC_012759.1 63429 65780 R Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II complement(63429..65780) Escherichia coli BW2952 7955993 YP_002925260.1 CDS araA NC_012759.1 66834 68336 R catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase complement(66834..68336) Escherichia coli BW2952 7952210 YP_002925261.1 CDS araB NC_012759.1 68347 70047 R catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase complement(68347..70047) Escherichia coli BW2952 7954115 YP_002925262.1 CDS araC NC_012759.1 70386 71264 D positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; AraC family transcriptional regulator 70386..71264 Escherichia coli BW2952 7954167 YP_002925263.1 CDS yabI NC_012759.1 71350 72114 D MG1655 equivalent: b0065; hypothetical protein 71350..72114 Escherichia coli BW2952 7953418 YP_002925264.1 CDS thiQ NC_012759.1 72228 72926 R with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit complement(72228..72926) Escherichia coli BW2952 7952698 YP_002925265.1 CDS thiP NC_012759.1 72910 74520 R permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein complement(72910..74520) Escherichia coli BW2952 7956130 YP_002925266.1 CDS tbpA NC_012759.1 74496 75479 R part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit complement(74496..75479) Escherichia coli BW2952 7953745 YP_002925267.1 CDS sgrR NC_012759.1 75643 77298 R activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR complement(75643..77298) Escherichia coli BW2952 7956131 YP_002925268.1 CDS setA NC_012759.1 77620 78798 D MG1655 equivalent: b0070; broad specificity sugar efflux system 77620..78798 Escherichia coli BW2952 7952168 YP_002925269.1 CDS leuD NC_012759.1 78847 79452 R catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit complement(78847..79452) Escherichia coli BW2952 7952585 YP_002925270.1 CDS leuC NC_012759.1 79463 80863 R dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit complement(79463..80863) Escherichia coli BW2952 7952306 YP_002925271.1 CDS leuB NC_012759.1 80866 81957 R catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase complement(80866..81957) Escherichia coli BW2952 7952307 YP_002925272.1 CDS leuA NC_012759.1 81957 83528 R catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase complement(81957..83528) Escherichia coli BW2952 7952305 YP_002925273.1 CDS leuL NC_012759.1 83621 83707 R involved in attenuation control of the leuABCD operon in leucine biosynthesis; leu operon leader peptide complement(83621..83707) Escherichia coli BW2952 7952259 YP_002925274.1 CDS leuO NC_012759.1 84367 85311 D activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 84367..85311 Escherichia coli BW2952 7954124 YP_002925275.1 CDS ilvI NC_012759.1 85629 87353 D catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 85629..87353 Escherichia coli BW2952 7953377 YP_002925276.1 CDS ilvH NC_012759.1 87356 87847 D with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 87356..87847 Escherichia coli BW2952 7952393 YP_002925277.1 CDS fruR NC_012759.1 88027 89031 D binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 88027..89031 Escherichia coli BW2952 7952394 YP_002925278.1 CDS mraZ NC_012759.1 89633 90091 D MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 89633..90091 Escherichia coli BW2952 7953419 YP_002925279.1 CDS mraW NC_012759.1 90093 91034 D MG1655 equivalent: b0082; S-adenosyl-methyltransferase MraW 90093..91034 Escherichia coli BW2952 7952914 YP_002925280.1 CDS ftsL NC_012759.1 91031 91396 D membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 91031..91396 Escherichia coli BW2952 7955997 YP_002925281.1 CDS ftsI NC_012759.1 91412 93178 D MG1655 equivalent: b0084; transpeptidase involved in septal peptidoglycan synthesis (penicillin-binding protein 3) 91412..93178 Escherichia coli BW2952 7954226 YP_002925282.1 CDS murE NC_012759.1 93165 94652 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 93165..94652 Escherichia coli BW2952 7956178 YP_002925283.1 CDS murF NC_012759.1 94649 96007 D MG1655 equivalent: b0086; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 94649..96007 Escherichia coli BW2952 7956244 YP_002925284.1 CDS mraY NC_012759.1 96001 97083 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 96001..97083 Escherichia coli BW2952 7956245 YP_002925285.1 CDS murD NC_012759.1 97086 98402 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 97086..98402 Escherichia coli BW2952 7954543 YP_002925286.1 CDS ftsW NC_012759.1 98402 99646 D integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 98402..99646 Escherichia coli BW2952 7956243 YP_002925287.1 CDS murG NC_012759.1 99643 100710 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase 99643..100710 Escherichia coli BW2952 7954009 YP_002925288.1 CDS murC NC_012759.1 100764 102239 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 100764..102239 Escherichia coli BW2952 7954342 YP_002925289.1 CDS ddl NC_012759.1 102232 103152 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 102232..103152 Escherichia coli BW2952 7956241 YP_002925290.1 CDS ftsQ NC_012759.1 103154 103984 D involved in septum formation; cell division protein FtsQ 103154..103984 Escherichia coli BW2952 7953215 YP_002925291.1 CDS ftsA NC_012759.1 103981 105243 D ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 103981..105243 Escherichia coli BW2952 7954223 YP_002925292.1 CDS ftsZ NC_012759.1 105304 106455 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 105304..106455 Escherichia coli BW2952 7952528 YP_002925293.1 CDS lpxC NC_012759.1 106556 107473 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 106556..107473 Escherichia coli BW2952 7953883 YP_002925294.1 CDS secM NC_012759.1 107704 108216 D secM translational pause allows for the initiation of secA translation; SecA regulator SecM 107704..108216 Escherichia coli BW2952 7956227 YP_002925295.1 CDS secA NC_012759.1 108278 110983 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 108278..110983 Escherichia coli BW2952 7955924 YP_002925296.1 CDS mutT NC_012759.1 111043 111432 D MG1655 equivalent: b0099; nucleoside triphosphate pyrophosphohydrolase 111043..111432 Escherichia coli BW2952 7955763 YP_002925297.1 CDS yacG NC_012759.1 111648 111845 R MG1655 equivalent: b0101; zinc-binding protein complement(111648..111845) Escherichia coli BW2952 7954413 YP_002925298.1 CDS yacF NC_012759.1 111855 112598 R MG1655 equivalent: b0102; hypothetical protein complement(111855..112598) Escherichia coli BW2952 7952755 YP_002925299.1 CDS coaE NC_012759.1 112598 113218 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(112598..113218) Escherichia coli BW2952 7952756 YP_002925300.1 CDS guaC NC_012759.1 113443 114486 D catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 113443..114486 Escherichia coli BW2952 7953238 YP_002925301.1 CDS hofC NC_012759.1 114521 115723 R MG1655 equivalent: b0106; type IV pilin biogenesis protein complement(114521..115723) Escherichia coli BW2952 7953872 YP_002925302.1 CDS hofB NC_012759.1 115713 117098 R MG1655 equivalent: b0107; hypothetical protein complement(115713..117098) Escherichia coli BW2952 7952520 YP_002925303.1 CDS ppdD NC_012759.1 117108 117548 R MG1655 equivalent: b0108; putative major pilin subunit complement(117108..117548) Escherichia coli BW2952 7953083 YP_002925304.1 CDS nadC NC_012759.1 117751 118644 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase complement(117751..118644) Escherichia coli BW2952 7955131 YP_002925305.1 CDS ampD NC_012759.1 118732 119283 D MG1655 equivalent: b0110; N-acetyl-anhydromuranmyl-L-alanine amidase 118732..119283 Escherichia coli BW2952 7955886 YP_002925306.1 CDS ampE NC_012759.1 119280 120134 D involved in regulation of beta-lactamase; putative signaling protein; regulatory protein AmpE 119280..120134 Escherichia coli BW2952 7954334 YP_002925307.1 CDS aroP NC_012759.1 120177 121550 R MG1655 equivalent: b0112; aromatic amino acid transporter complement(120177..121550) Escherichia coli BW2952 7955022 YP_002925308.1 CDS pdhR NC_012759.1 122091 122855 D activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 122091..122855 Escherichia coli BW2952 7952504 YP_002925309.1 CDS aceE NC_012759.1 123016 125679 D E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 123016..125679 Escherichia coli BW2952 7953420 YP_002925310.1 CDS aceF NC_012759.1 125694 127586 D E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 125694..127586 Escherichia coli BW2952 7955845 YP_002925311.1 CDS lpd NC_012759.1 127911 129335 D E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 127911..129335 Escherichia coli BW2952 7955846 YP_002925312.1 CDS yacH NC_012759.1 129406 131259 R MG1655 equivalent: b0117; hypothetical protein complement(129406..131259) Escherichia coli BW2952 7954146 YP_002925313.1 CDS acnB NC_012759.1 131614 134211 D catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 131614..134211 Escherichia coli BW2952 7955334 YP_002925314.1 CDS yacL NC_012759.1 134387 134749 D MG1655 equivalent: b0119; hypothetical protein 134387..134749 Escherichia coli BW2952 7952561 YP_002925315.1 CDS speD NC_012759.1 134787 135581 R S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase complement(134787..135581) Escherichia coli BW2952 7952915 YP_002925316.1 CDS speE NC_012759.1 135597 136463 R catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase complement(135597..136463) Escherichia coli BW2952 7955998 YP_002925317.1 CDS yacC NC_012759.1 136569 136916 R MG1655 equivalent: b0122; hypothetical protein complement(136569..136916) Escherichia coli BW2952 7956062 YP_002925318.1 CDS cueO NC_012759.1 137082 138632 D laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 137082..138632 Escherichia coli BW2952 7955335 YP_002925319.1 CDS gcd NC_012759.1 138834 141224 R MG1655 equivalent: b0124; glucose dehydrogenase complement(138834..141224) Escherichia coli BW2952 7954296 YP_002925320.1 CDS hpt NC_012759.1 141430 141966 D MG1655 equivalent: b0125; hypoxanthine phosphoribosyltransferase 141430..141966 Escherichia coli BW2952 7953803 YP_002925321.1 CDS can NC_012759.1 142007 142669 R catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase complement(142007..142669) Escherichia coli BW2952 7953988 YP_002925322.1 CDS yadG NC_012759.1 142778 143704 D MG1655 equivalent: b0127; putative transporter subunit: ATP-binding component of ABC superfamily 142778..143704 Escherichia coli BW2952 7952597 YP_002925323.1 CDS yadH NC_012759.1 143701 144471 D MG1655 equivalent: b0128; putative transporter subunit: membrane component of ABC superfamily 143701..144471 Escherichia coli BW2952 7955720 YP_002925324.1 CDS yadI NC_012759.1 144576 145016 D MG1655 equivalent: b0129; putative PTS Enzyme IIA 144576..145016 Escherichia coli BW2952 7955733 YP_002925325.1 CDS yadE NC_012759.1 145080 146309 D MG1655 equivalent: b0130; putative polysaccharide deacetylase lipoprotein 145080..146309 Escherichia coli BW2952 7955549 YP_002925326.1 CDS panD NC_012759.1 146313 146693 R Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase complement(146313..146693) Escherichia coli BW2952 7955326 YP_002925327.1 CDS yadD NC_012759.1 146967 147869 D MG1655 equivalent: b0132; putative transposase 146967..147869 Escherichia coli BW2952 7952510 YP_002925328.1 CDS panC NC_012759.1 147943 148794 R catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase complement(147943..148794) Escherichia coli BW2952 7955739 YP_002925329.1 CDS panB NC_012759.1 148806 149600 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(148806..149600) Escherichia coli BW2952 7954465 YP_002925330.1 CDS yadC NC_012759.1 149714 150952 R MG1655 equivalent: b0135; putative fimbrial-like adhesin protein complement(149714..150952) Escherichia coli BW2952 7952312 YP_002925331.1 CDS yadK NC_012759.1 151002 151598 R MG1655 equivalent: b0136; putative fimbrial-like adhesin protein complement(151002..151598) Escherichia coli BW2952 7954876 YP_002925332.1 CDS yadL NC_012759.1 151625 152230 R MG1655 equivalent: b0137; putative fimbrial-like adhesin protein complement(151625..152230) Escherichia coli BW2952 7954877 YP_002925333.1 CDS yadM NC_012759.1 152242 152811 R MG1655 equivalent: b0138; putative fimbrial-like adhesin protein complement(152242..152811) Escherichia coli BW2952 7954878 YP_002925334.1 CDS htrE NC_012759.1 152828 155425 R similar to the fimbrial usher protein PapC; putative outer membrane usher protein complement(152828..155425) Escherichia coli BW2952 7954879 YP_002925335.1 CDS ecpD NC_012759.1 155460 156200 R MG1655 equivalent: b0140; putative chaperone protein EcpD complement(155460..156200) Escherichia coli BW2952 7955218 YP_002925336.1 CDS yadN NC_012759.1 156298 156882 R MG1655 equivalent: b0141; putative fimbrial-like adhesin protein complement(156298..156882) Escherichia coli BW2952 7955300 YP_002925337.1 CDS folK NC_012759.1 157252 157731 R catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase complement(157252..157731) Escherichia coli BW2952 7954880 YP_002925338.1 CDS pcnB NC_012759.1 157728 159125 R Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase I complement(157728..159125) Escherichia coli BW2952 7952252 YP_002925339.1 CDS yadB NC_012759.1 159185 160081 R this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase complement(159185..160081) Escherichia coli BW2952 7954562 YP_002925340.1 CDS dksA NC_012759.1 160148 160603 R MG1655 equivalent: b0145; RNA polymerase-binding transcription factor complement(160148..160603) Escherichia coli BW2952 7953832 YP_002925341.1 CDS sfsA NC_012759.1 160781 161485 R Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A complement(160781..161485) Escherichia coli BW2952 7953447 YP_002925342.1 CDS ligT NC_012759.1 161500 162030 R MG1655 equivalent: b0147; 2'-5' RNA ligase complement(161500..162030) Escherichia coli BW2952 7954744 YP_002925343.1 CDS hrpB NC_012759.1 162104 164533 D similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 162104..164533 Escherichia coli BW2952 7952251 YP_002925344.1 CDS mrcB NC_012759.1 164729 167263 D bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 164729..167263 Escherichia coli BW2952 7954663 YP_002925345.1 CDS fhuA NC_012759.1 167483 169726 D involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 167483..169726 Escherichia coli BW2952 7953685 YP_002925346.1 CDS fhuC NC_012759.1 169777 170574 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 169777..170574 Escherichia coli BW2952 7953570 YP_002925347.1 CDS fhuD NC_012759.1 170574 171464 D Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 170574..171464 Escherichia coli BW2952 7954018 YP_002925348.1 CDS fhuB NC_012759.1 171461 173443 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 171461..173443 Escherichia coli BW2952 7954019 YP_002925349.1 CDS hemL NC_012759.1 173601 174881 R Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase complement(173601..174881) Escherichia coli BW2952 7953690 YP_002925350.1 CDS clcA NC_012759.1 175106 176527 D Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 175106..176527 Escherichia coli BW2952 7953826 YP_002925351.1 CDS erpA NC_012759.1 176609 176953 D essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 176609..176953 Escherichia coli BW2952 7952634 YP_002925352.1 CDS yadS NC_012759.1 177000 177623 R MG1655 equivalent: b0157; hypothetical protein complement(177000..177623) Escherichia coli BW2952 7952916 YP_002925353.1 CDS btuF NC_012759.1 177661 178461 R solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF complement(177661..178461) Escherichia coli BW2952 7952662 YP_002925354.1 CDS mtn NC_012759.1 178454 179152 R enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase complement(178454..179152) Escherichia coli BW2952 7956273 YP_002925355.1 CDS dgt NC_012759.1 179236 180753 D forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 179236..180753 Escherichia coli BW2952 7952375 YP_002925356.1 CDS degP NC_012759.1 180883 182307 D protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 180883..182307 Escherichia coli BW2952 7953234 YP_002925357.1 CDS cdaR NC_012759.1 182462 183619 D regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 182462..183619 Escherichia coli BW2952 7956029 YP_002925358.1 CDS yaeH NC_012759.1 183708 184094 R MG1655 equivalent: b0163; hypothetical protein complement(183708..184094) Escherichia coli BW2952 7953378 YP_002925359.1 CDS yaeI NC_012759.1 184256 185068 R MG1655 equivalent: b0164; phosphodiesterase YaeI complement(184256..185068) Escherichia coli BW2952 7952757 YP_002925360.1 CDS dapD NC_012759.1 185122 185946 R catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase complement(185122..185946) Escherichia coli BW2952 7955310 YP_002925361.1 CDS glnD NC_012759.1 185977 188649 R catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase complement(185977..188649) Escherichia coli BW2952 7952231 YP_002925362.1 CDS map NC_012759.1 188711 189505 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase complement(188711..189505) Escherichia coli BW2952 7956265 YP_002925363.1 CDS rpsB NC_012759.1 189873 190598 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 189873..190598 Escherichia coli BW2952 7952169 YP_002925364.1 CDS tsf NC_012759.1 190856 191707 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 190856..191707 Escherichia coli BW2952 7952283 YP_002925365.1 CDS pyrH NC_012759.1 191854 192579 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 191854..192579 Escherichia coli BW2952 7955786 YP_002925366.1 CDS frr NC_012759.1 192871 193428 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 192871..193428 Escherichia coli BW2952 7956264 YP_002925367.1 CDS dxr NC_012759.1 193520 194716 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 193520..194716 Escherichia coli BW2952 7955978 YP_002925368.1 CDS ispU NC_012759.1 194902 195663 D catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase 194902..195663 Escherichia coli BW2952 7952227 YP_002925369.1 CDS cdsA NC_012759.1 195676 196533 D catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 195676..196533 Escherichia coli BW2952 7956252 YP_002925370.1 CDS rseP NC_012759.1 196545 197897 D catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 196545..197897 Escherichia coli BW2952 7952613 YP_002925371.1 CDS bamA NC_012759.1 197927 200359 D part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 197927..200359 Escherichia coli BW2952 7956283 YP_002925372.1 CDS skp NC_012759.1 200481 200966 D MG1655 equivalent: b0178; periplasmic chaperone 200481..200966 Escherichia coli BW2952 7952917 YP_002925373.1 CDS lpxD NC_012759.1 200970 201995 D adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 200970..201995 Escherichia coli BW2952 7954487 YP_002925374.1 CDS fabZ NC_012759.1 202100 202555 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 202100..202555 Escherichia coli BW2952 7956226 YP_002925375.1 CDS lpxA NC_012759.1 202559 203347 D catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 202559..203347 Escherichia coli BW2952 7952214 YP_002925376.1 CDS lpxB NC_012759.1 203347 204495 D catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 203347..204495 Escherichia coli BW2952 7956240 YP_002925377.1 CDS rnhB NC_012759.1 204492 205088 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 204492..205088 Escherichia coli BW2952 7956120 YP_002925378.1 CDS dnaE NC_012759.1 205125 208607 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 205125..208607 Escherichia coli BW2952 7955960 YP_002925379.1 CDS accA NC_012759.1 208620 209579 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 208620..209579 Escherichia coli BW2952 7953318 YP_002925380.1 CDS ldcC NC_012759.1 209678 211819 D MG1655 equivalent: b0186; lysine decarboxylase 2, constitutive 209678..211819 Escherichia coli BW2952 7952401 YP_002925381.1 CDS yaeR NC_012759.1 211876 212265 D MG1655 equivalent: b0187; hypothetical protein 211876..212265 Escherichia coli BW2952 7954181 YP_002925382.1 CDS tilS NC_012759.1 212330 213628 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 212330..213628 Escherichia coli BW2952 7955126 YP_002925383.1 CDS rof NC_012759.1 213677 213931 R Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator complement(213677..213931) Escherichia coli BW2952 7956203 YP_002925384.1 CDS yaeP NC_012759.1 213924 214124 R MG1655 equivalent: b4406; hypothetical protein complement(213924..214124) Escherichia coli BW2952 7954279 YP_002925385.1 CDS yaeQ NC_012759.1 214290 214835 D MG1655 equivalent: b0190; hypothetical protein 214290..214835 Escherichia coli BW2952 7952908 YP_002925386.1 CDS yaeJ NC_012759.1 214832 215254 D MG1655 equivalent: b0191; peptidyl-tRNA hydrolase domain-containing protein 214832..215254 Escherichia coli BW2952 7952918 YP_002925387.1 CDS nlpE NC_012759.1 215268 215978 D MG1655 equivalent: b0192; lipoprotein involved with copper homeostasis and adhesion 215268..215978 Escherichia coli BW2952 7952919 YP_002925388.1 CDS yaeF NC_012759.1 216178 217002 R MG1655 equivalent: b0193; hypothetical protein complement(216178..217002) Escherichia coli BW2952 7954157 YP_002925389.1 CDS proS NC_012759.1 217056 218774 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(217056..218774) Escherichia coli BW2952 7955102 YP_002925390.1 CDS yaeB NC_012759.1 218886 219593 R MG1655 equivalent: b0195; hypothetical protein complement(218886..219593) Escherichia coli BW2952 7955772 YP_002925391.1 CDS rcsF NC_012759.1 219590 219994 R MG1655 equivalent: b0196; outer membrane lipoprotein complement(219590..219994) Escherichia coli BW2952 7952758 YP_002925392.1 CDS metQ NC_012759.1 220112 220927 R MG1655 equivalent: b0197; DL-methionine transporter substrate-binding subunit complement(220112..220927) Escherichia coli BW2952 7955217 YP_002925393.1 CDS metI NC_012759.1 220967 221620 R part of the MetNIQ methionine uptake system; DL-methionine transporter permease complement(220967..221620) Escherichia coli BW2952 7953273 YP_002925394.1 CDS metN NC_012759.1 221613 222644 R part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit complement(221613..222644) Escherichia coli BW2952 7953274 YP_002925395.1 CDS gmhB NC_012759.1 222832 223407 D Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 222832..223407 Escherichia coli BW2952 7953275 YP_002925396.1 CDS dkgB NC_012759.1 229166 229969 D catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 229166..229969 Escherichia coli BW2952 7952117 YP_002925397.1 CDS yafC NC_012759.1 229966 230880 R MG1655 equivalent: b0208; putative DNA-binding transcriptional regulator complement(229966..230880) Escherichia coli BW2952 7952239 YP_002925398.1 CDS yafD NC_012759.1 231121 231921 D MG1655 equivalent: b0209; hypothetical protein 231121..231921 Escherichia coli BW2952 7954745 YP_002925399.1 CDS yafE NC_012759.1 231925 232548 D MG1655 equivalent: b0210; putative S-adenosyl-L-methionine-dependent methyltransferase 231925..232548 Escherichia coli BW2952 7952920 YP_002925400.1 CDS mltD NC_012759.1 232596 233954 R catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D complement(232596..233954) Escherichia coli BW2952 7955576 YP_002925401.1 CDS gloB NC_012759.1 234026 234781 R catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase complement(234026..234781) Escherichia coli BW2952 7955142 YP_002925402.1 CDS yafS NC_012759.1 234815 235537 D MG1655 equivalent: b0213; putative S-adenosyl-L-methionine-dependent methyltransferase 234815..235537 Escherichia coli BW2952 7954980 YP_002925403.1 CDS rnhA NC_012759.1 235534 236001 R An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H complement(235534..236001) Escherichia coli BW2952 7955577 YP_002925404.1 CDS dnaQ NC_012759.1 236066 236797 D 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 236066..236797 Escherichia coli BW2952 7955959 YP_002925405.1 CDS yafT NC_012759.1 237334 238119 D MG1655 equivalent: b0217; putative aminopeptidase 237334..238119 Escherichia coli BW2952 7952118 YP_002925406.1 CDS ykfM NC_012759.1 238256 238735 R MG1655 equivalent: b4586; hypothetical protein complement(238256..238735) Escherichia coli BW2952 7954646 YP_002925407.1 CDS yafV NC_012759.1 239418 240188 R MG1655 equivalent: b0219; hypothetical protein complement(239418..240188) Escherichia coli BW2952 7953984 YP_002925408.1 CDS ivy NC_012759.1 240342 240815 D inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 240342..240815 Escherichia coli BW2952 7954695 YP_002925409.1 CDS fadE NC_012759.1 240858 243302 R functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase complement(240858..243302) Escherichia coli BW2952 7953995 YP_002925410.1 CDS gmhA NC_012759.1 243542 244120 D catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 243542..244120 Escherichia coli BW2952 7952414 YP_002925411.1 CDS yafJ NC_012759.1 244326 245093 D MG1655 equivalent: b0223; putative amidotransfease 244326..245093 Escherichia coli BW2952 7953496 YP_002925412.1 CDS yafK NC_012759.1 245064 245804 R MG1655 equivalent: b0224; hypothetical protein complement(245064..245804) Escherichia coli BW2952 7954638 YP_002925413.1 CDS yafQ NC_012759.1 245960 246238 R MG1655 equivalent: b0225; putative toxin of the YafQ-DinJ toxin-antitoxin system complement(245960..246238) Escherichia coli BW2952 7952759 YP_002925414.1 CDS dinJ NC_012759.1 246241 246501 R MG1655 equivalent: b0226; putative antitoxin of YafQ-DinJ toxin-antitoxin system complement(246241..246501) Escherichia coli BW2952 7955627 YP_002925415.1 CDS yafL NC_012759.1 246711 247460 D MG1655 equivalent: b0227; putative lipoprotein and C40 family peptidase 246711..247460 Escherichia coli BW2952 7954656 YP_002925416.1 CDS yafM NC_012759.1 247636 248133 D MG1655 equivalent: b0228; hypothetical protein 247636..248133 Escherichia coli BW2952 7955120 YP_002925417.1 CDS dinB NC_012759.1 250897 251952 D involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 250897..251952 Escherichia coli BW2952 7952921 YP_002925418.1 CDS yafN NC_012759.1 252004 252297 D MG1655 equivalent: b0232; putative antitoxin of the YafO-YafN toxin-antitoxin system 252004..252297 Escherichia coli BW2952 7953327 YP_002925419.1 CDS yafO NC_012759.1 252300 252698 D YafO overproduction induces toxicity; it is believed to be the toxin of a toxin-antitoxin pair; unknown function; putative toxin YafO 252300..252698 Escherichia coli BW2952 7954655 YP_002925420.1 CDS yafP NC_012759.1 252708 253160 D MG1655 equivalent: b0234; hypothetical protein 252708..253160 Escherichia coli BW2952 7955626 YP_002925421.1 CDS pepD NC_012759.1 254258 255715 R MG1655 equivalent: b0237; aminoacyl-histidine dipeptidase complement(254258..255715) Escherichia coli BW2952 7954620 YP_002925422.1 CDS gpt NC_012759.1 255976 256434 D catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 255976..256434 Escherichia coli BW2952 7952464 YP_002925423.1 CDS frsA NC_012759.1 256526 257770 D forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 256526..257770 Escherichia coli BW2952 7953885 YP_002925424.1 CDS crl NC_012759.1 257828 258229 D involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 257828..258229 Escherichia coli BW2952 7953957 YP_002925425.1 CDS phoE NC_012759.1 258268 259323 R MG1655 equivalent: b0241; outer membrane phosphoporin protein E complement(258268..259323) Escherichia coli BW2952 7953442 YP_002925426.1 CDS proB NC_012759.1 259611 260714 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 259611..260714 Escherichia coli BW2952 7954442 YP_002925427.1 CDS proA NC_012759.1 260726 261979 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 260726..261979 Escherichia coli BW2952 7953768 YP_002925428.1 CDS ykfI NC_012759.1 262551 262892 R MG1655 equivalent: b0245; CP4-6 prophage; toxin of the YkfI-YafW toxin-antitoxin system complement(262551..262892) Escherichia coli BW2952 7952119 YP_002925429.1 CDS yafW NC_012759.1 262913 263230 R MG1655 equivalent: b0246; CP4-6 prophage; antitoxin of the YkfI-YafW toxin-antitoxin system complement(262913..263230) Escherichia coli BW2952 7953139 YP_002925430.1 CDS ykfH NC_012759.1 263249 263470 R MG1655 equivalent: b4504; hypothetical protein complement(263249..263470) Escherichia coli BW2952 7953130 YP_002925431.1 CDS ykfG NC_012759.1 263479 263955 R MG1655 equivalent: b0247; CP4-6 prophage; putative DNA repair protein complement(263479..263955) Escherichia coli BW2952 7955432 YP_002925432.1 CDS yafX NC_012759.1 263971 264429 R MG1655 equivalent: b0248; CP4-6 prophage protein complement(263971..264429) Escherichia coli BW2952 7953132 YP_002925433.1 CDS ykfF NC_012759.1 264527 264766 R MG1655 equivalent: b0249; CP4-6 prophage protein complement(264527..264766) Escherichia coli BW2952 7953136 YP_002925434.1 CDS ykfB NC_012759.1 264843 265310 R MG1655 equivalent: b0250; CP4-6 prophage protein complement(264843..265310) Escherichia coli BW2952 7953137 YP_002925435.1 CDS yafY NC_012759.1 265333 265776 R MG1655 equivalent: b0251; CP4-6 prophage; putative DNA-binding transcriptional regulator complement(265333..265776) Escherichia coli BW2952 7953138 YP_002925436.1 CDS yafZ NC_012759.1 266407 267228 R MG1655 equivalent: b0252; CP4-6 prophage protein complement(266407..267228) Escherichia coli BW2952 7953133 YP_002925437.1 CDS ykfA NC_012759.1 267320 268183 R MG1655 equivalent: b0253; CP4-6 prophage; putative GTP-binding protein complement(267320..268183) Escherichia coli BW2952 7953131 YP_002925438.1 CDS perR NC_012759.1 268512 269405 R MG1655 equivalent: b0254; CP4-6 prophage; putative DNA-binding transcriptional regulator complement(268512..269405) Escherichia coli BW2952 7953135 YP_002925439.1 CDS insI NC_012759.1 269826 270977 D MG1655 equivalent: b0256; KpLE2 phage-like element; IS30 transposase 269826..270977 Escherichia coli BW2952 7953134 YP_002925440.1 CDS insH NC_012759.1 273324 274340 R MG1655 equivalent: b0259; IS5 transposase and trans-activator complement(273324..274340) Escherichia coli BW2952 7954084 YP_002925441.1 CDS mhpD NC_012759.1 274524 274907 D MG1655 equivalent: b0350; 2-keto-4-pentenoate hydratase 274524..274907 Escherichia coli BW2952 7954036 YP_002925442.1 CDS mhpF NC_012759.1 274904 275854 D catalyzes the formation of acetyl-CoA from acetalaldehyde; acetaldehyde dehydrogenase 274904..275854 Escherichia coli BW2952 7952261 YP_002925443.1 CDS mhpE NC_012759.1 275851 276864 D catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate; 4-hydroxy-2-ketovalerate aldolase 275851..276864 Escherichia coli BW2952 7952387 YP_002925444.1 CDS mhpT NC_012759.1 277442 278653 D MG1655 equivalent: b0353; putative 3-hydroxyphenylpropionic transporter MhpT 277442..278653 Escherichia coli BW2952 7952334 YP_002925445.1 CDS yaiL NC_012759.1 278755 279294 D MG1655 equivalent: b0354; nucleoprotein/polynucleotide-associated enzyme 278755..279294 Escherichia coli BW2952 7954588 YP_002925446.1 CDS frmB NC_012759.1 279518 280351 R MG1655 equivalent: b0355; putative esterase complement(279518..280351) Escherichia coli BW2952 7954408 YP_002925447.1 CDS frmA NC_012759.1 280445 281554 R MG1655 equivalent: b0356; alcohol dehydrogenase complement(280445..281554) Escherichia coli BW2952 7954861 YP_002925448.1 CDS frmR NC_012759.1 281589 281864 R formaldehyde-induced negative regulator of the frmRAB operon; regulator protein FrmR complement(281589..281864) Escherichia coli BW2952 7952441 YP_002925449.1 CDS yaiO NC_012759.1 282052 282825 R MG1655 equivalent: b0358; hypothetical protein complement(282052..282825) Escherichia coli BW2952 7955926 YP_002925450.1 CDS insC NC_012759.1 283334 283699 D IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 283334..283699 Escherichia coli BW2952 7955336 YP_002925451.1 CDS insD NC_012759.1 283657 284562 D IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 283657..284562 Escherichia coli BW2952 7954074 YP_002925452.1 CDS yaiP NC_012759.1 284722 285918 R MG1655 equivalent: b0363; putative glucosyltransferase complement(284722..285918) Escherichia coli BW2952 7954080 YP_002925453.1 CDS yaiS NC_012759.1 286042 286599 R MG1655 equivalent: b0364; hypothetical protein complement(286042..286599) Escherichia coli BW2952 7954920 YP_002925454.1 CDS tauA NC_012759.1 287215 288177 D with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 287215..288177 Escherichia coli BW2952 7952760 YP_002925455.1 CDS tauB NC_012759.1 288190 288957 D Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit 288190..288957 Escherichia coli BW2952 7956114 YP_002925456.1 CDS tauC NC_012759.1 288954 289781 D MG1655 equivalent: b0367; taurine transporter subunit 288954..289781 Escherichia coli BW2952 7956115 YP_002925457.1 CDS tauD NC_012759.1 289778 290629 D catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 289778..290629 Escherichia coli BW2952 7956116 YP_002925458.1 CDS hemB NC_012759.1 290736 291710 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(290736..291710) Escherichia coli BW2952 7956113 YP_002925459.1 CDS insF NC_012759.1 293722 294588 R MG1655 equivalent: b0372; IS3 element protein InsF complement(293722..294588) Escherichia coli BW2952 7954570 YP_002925460.1 CDS insE NC_012759.1 294585 294893 R MG1655 equivalent: b0373; IS3 element protein InsE complement(294585..294893) Escherichia coli BW2952 7954032 YP_002925461.1 CDS yaiV NC_012759.1 296444 297112 D MG1655 equivalent: b0375; putative DNA-binding transcriptional regulator 296444..297112 Escherichia coli BW2952 7954028 YP_002925462.1 CDS ampH NC_012759.1 297113 298270 R this protein has no known enzymatic function; beta-lactam binding protein AmpH complement(297113..298270) Escherichia coli BW2952 7954789 YP_002925463.1 CDS sbmA NC_012759.1 298622 299842 D in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transporter 298622..299842 Escherichia coli BW2952 7952552 YP_002925464.1 CDS yaiW NC_012759.1 299855 300949 D MG1655 equivalent: b0378; putative DNA-binding transcriptional regulator 299855..300949 Escherichia coli BW2952 7955678 YP_002925465.1 CDS yaiY NC_012759.1 301008 301316 R MG1655 equivalent: b0379; putative inner membrane protein complement(301008..301316) Escherichia coli BW2952 7954790 YP_002925466.1 CDS yaiZ NC_012759.1 301576 301788 D MG1655 equivalent: b0380; putative inner membrane protein 301576..301788 Escherichia coli BW2952 7954985 YP_002925467.1 CDS ddl NC_012759.1 301812 302906 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(301812..302906) Escherichia coli BW2952 7955023 YP_002925468.1 CDS iraP NC_012759.1 303369 303629 D MG1655 equivalent: b0382; hypothetical protein 303369..303629 Escherichia coli BW2952 7953216 YP_002925469.1 CDS phoA NC_012759.1 303730 305145 D MG1655 equivalent: b0383; alkaline phosphatase 303730..305145 Escherichia coli BW2952 7955440 YP_002925470.1 CDS psiF NC_012759.1 305264 305584 D MG1655 equivalent: b0384; hypothetical protein 305264..305584 Escherichia coli BW2952 7952540 YP_002925471.1 CDS adrA NC_012759.1 305686 306801 D catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 305686..306801 Escherichia coli BW2952 7952922 YP_002925472.1 CDS proC NC_012759.1 306818 307627 R catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase complement(306818..307627) Escherichia coli BW2952 7954726 YP_002925473.1 CDS yaiI NC_012759.1 307747 308205 D MG1655 equivalent: b0387; hypothetical protein 307747..308205 Escherichia coli BW2952 7955843 YP_002925474.1 CDS aroL NC_012759.1 308388 308912 D type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 308388..308912 Escherichia coli BW2952 7952923 YP_002925475.1 CDS yaiA NC_012759.1 308962 309153 D MG1655 equivalent: b0389; hypothetical protein 308962..309153 Escherichia coli BW2952 7956038 YP_002925476.1 CDS aroM NC_012759.1 309411 310088 D MG1655 equivalent: b0390; hypothetical protein 309411..310088 Escherichia coli BW2952 7955441 YP_002925477.1 CDS yaiE NC_012759.1 310160 310444 D MG1655 equivalent: b0391; hypothetical protein 310160..310444 Escherichia coli BW2952 7952924 YP_002925478.1 CDS rdgC NC_012759.1 311091 312002 R Required for efficient pilin antigenic variation; recombination associated protein complement(311091..312002) Escherichia coli BW2952 7952925 YP_002925479.1 CDS mak NC_012759.1 312127 313035 D catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 312127..313035 Escherichia coli BW2952 7953341 YP_002925480.1 CDS araJ NC_012759.1 313280 314464 R member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ complement(313280..314464) Escherichia coli BW2952 7954212 YP_002925481.1 CDS sbcC NC_012759.1 314590 317736 R with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease subunit SbcC complement(314590..317736) Escherichia coli BW2952 7955648 YP_002925482.1 CDS sbcD NC_012759.1 317733 318935 R with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease subunit SbcD complement(317733..318935) Escherichia coli BW2952 7953546 YP_002925483.1 CDS phoB NC_012759.1 319125 319814 D two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB 319125..319814 Escherichia coli BW2952 7953547 YP_002925484.1 CDS phoR NC_012759.1 319872 321167 D membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 319872..321167 Escherichia coli BW2952 7953358 YP_002925485.1 CDS brnQ NC_012759.1 321574 322893 D MG1655 equivalent: b0401; putative branched chain amino acid transporter (LIV-II) 321574..322893 Escherichia coli BW2952 7956023 YP_002925486.1 CDS proY NC_012759.1 322969 324342 D cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; putative proline-specific permease 322969..324342 Escherichia coli BW2952 7954671 YP_002925487.1 CDS malZ NC_012759.1 324498 326315 D MG1655 equivalent: b0403; maltodextrin glucosidase 324498..326315 Escherichia coli BW2952 7954703 YP_002925488.1 CDS acpH NC_012759.1 326320 326901 R Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; acyl carrier protein phosphodiesterase complement(326320..326901) Escherichia coli BW2952 7954203 YP_002925489.1 CDS queA NC_012759.1 326994 328064 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 326994..328064 Escherichia coli BW2952 7952761 YP_002925490.1 CDS tgt NC_012759.1 328120 329247 D Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 328120..329247 Escherichia coli BW2952 7955999 YP_002925491.1 CDS yajC NC_012759.1 329270 329602 D member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 329270..329602 Escherichia coli BW2952 7956207 YP_002925492.1 CDS secD NC_012759.1 329630 331477 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 329630..331477 Escherichia coli BW2952 7956003 YP_002925493.1 CDS secF NC_012759.1 331488 332459 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 331488..332459 Escherichia coli BW2952 7956004 YP_002925494.1 CDS yajD NC_012759.1 332588 332935 D MG1655 equivalent: b0410; hypothetical protein 332588..332935 Escherichia coli BW2952 7956005 YP_002925495.1 CDS tsx NC_012759.1 333112 333996 R MG1655 equivalent: b0411; nucleoside channel phage T6/colicin K receptor complement(333112..333996) Escherichia coli BW2952 7952926 YP_002925496.1 CDS yajI NC_012759.1 334295 334834 R MG1655 equivalent: b0412; hypothetical protein complement(334295..334834) Escherichia coli BW2952 7954410 YP_002925497.1 CDS nrdR NC_012759.1 334985 335434 D MG1655 equivalent: b0413; transcriptional regulator NrdR 334985..335434 Escherichia coli BW2952 7955103 YP_002925498.1 CDS ribD NC_012759.1 335438 336541 D riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 335438..336541 Escherichia coli BW2952 7952927 YP_002925499.1 CDS ribH NC_012759.1 336630 337100 D RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 336630..337100 Escherichia coli BW2952 7953672 YP_002925500.1 CDS nusB NC_012759.1 337120 337539 D Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 337120..337539 Escherichia coli BW2952 7955953 YP_002925501.1 CDS thiL NC_012759.1 337617 338594 D catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 337617..338594 Escherichia coli BW2952 7956166 YP_002925502.1 CDS pgpA NC_012759.1 338572 339090 D hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 338572..339090 Escherichia coli BW2952 7956132 YP_002925503.1 CDS yajO NC_012759.1 339144 340118 R MG1655 equivalent: b0419; 2-carboxybenzaldehyde reductase complement(339144..340118) Escherichia coli BW2952 7954522 YP_002925504.1 CDS dxs NC_012759.1 340298 342160 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(340298..342160) Escherichia coli BW2952 7952253 YP_002925505.1 CDS ispA NC_012759.1 342185 343084 R MG1655 equivalent: b0421; geranyltranstransferase complement(342185..343084) Escherichia coli BW2952 7952228 YP_002925506.1 CDS xseB NC_012759.1 343084 343326 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(343084..343326) Escherichia coli BW2952 7953787 YP_002925507.1 CDS thiI NC_012759.1 343532 344980 D Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 343532..344980 Escherichia coli BW2952 7953544 YP_002925508.1 CDS yajL NC_012759.1 345034 345624 R MG1655 equivalent: b0424; DJ-1 family protein complement(345034..345624) Escherichia coli BW2952 7956097 YP_002925509.1 CDS panE NC_012759.1 345587 346498 R ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase complement(345587..346498) Escherichia coli BW2952 7952762 YP_002925510.1 CDS yajQ NC_012759.1 346666 347157 D putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; putative nucleotide-binding protein 346666..347157 Escherichia coli BW2952 7952255 YP_002925511.1 CDS yajR NC_012759.1 347285 348649 R MG1655 equivalent: b0427; putative transporter complement(347285..348649) Escherichia coli BW2952 7955187 YP_002925512.1 CDS cyoE NC_012759.1 348798 349688 R converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase complement(348798..349688) Escherichia coli BW2952 7955649 YP_002925513.1 CDS cyoD NC_012759.1 349700 350029 R MG1655 equivalent: b0429; cytochrome o ubiquinol oxidase subunit IV complement(349700..350029) Escherichia coli BW2952 7955815 YP_002925514.1 CDS cyoC NC_012759.1 350029 350643 R MG1655 equivalent: b0430; cytochrome o ubiquinol oxidase subunit III complement(350029..350643) Escherichia coli BW2952 7953199 YP_002925515.1 CDS cyoB NC_012759.1 350633 352624 R MG1655 equivalent: b0431; cytochrome o ubiquinol oxidase subunit I complement(350633..352624) Escherichia coli BW2952 7953198 YP_002925516.1 CDS cyoA NC_012759.1 352646 353593 R MG1655 equivalent: b0432; cytochrome o ubiquinol oxidase subunit II complement(352646..353593) Escherichia coli BW2952 7953196 YP_002925517.1 CDS ampG NC_012759.1 354053 355528 R in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter complement(354053..355528) Escherichia coli BW2952 7953197 YP_002925518.1 CDS yajG NC_012759.1 355572 356150 R MG1655 equivalent: b0434; hypothetical protein complement(355572..356150) Escherichia coli BW2952 7954324 YP_002925519.1 CDS bolA NC_012759.1 356455 356772 D positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 356455..356772 Escherichia coli BW2952 7955104 YP_002925520.1 CDS tig NC_012759.1 357116 358414 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 357116..358414 Escherichia coli BW2952 7955923 YP_002925521.1 CDS clpP NC_012759.1 358660 359283 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 358660..359283 Escherichia coli BW2952 7954479 YP_002925522.1 CDS clpX NC_012759.1 359409 360683 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 359409..360683 Escherichia coli BW2952 7955814 YP_002925523.1 CDS lon NC_012759.1 360871 363225 D MG1655 equivalent: b0439; DNA-binding ATP-dependent protease La 360871..363225 Escherichia coli BW2952 7952525 YP_002925524.1 CDS hupB NC_012759.1 363434 363706 D histone-like DNA-binding protein; transcriptional regulator HU subunit beta 363434..363706 Escherichia coli BW2952 7953338 YP_002925525.1 CDS ppiD NC_012759.1 363898 365769 D MG1655 equivalent: b0441; peptidyl-prolyl cis-trans isomerase 363898..365769 Escherichia coli BW2952 7953927 YP_002925526.1 CDS ybaV NC_012759.1 365920 366291 D MG1655 equivalent: b0442; hypothetical protein 365920..366291 Escherichia coli BW2952 7954481 YP_002925527.1 CDS ybaW NC_012759.1 366385 366783 D MG1655 equivalent: b0443; hypothetical protein 366385..366783 Escherichia coli BW2952 7952928 YP_002925528.1 CDS queC NC_012759.1 366835 367530 R YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC complement(366835..367530) Escherichia coli BW2952 7952929 YP_002925529.1 CDS ybaE NC_012759.1 367595 369295 R MG1655 equivalent: b0445; putative transporter subunit: periplasmic-binding component of ABC superfamily complement(367595..369295) Escherichia coli BW2952 7954636 YP_002925530.1 CDS cof NC_012759.1 369395 370213 D MG1655 equivalent: b0446; thiamin pyrimidine pyrophosphate hydrolase 369395..370213 Escherichia coli BW2952 7955734 YP_002925531.1 CDS ybaO NC_012759.1 370366 370824 D MG1655 equivalent: b0447; putative DNA-binding transcriptional regulator 370366..370824 Escherichia coli BW2952 7956129 YP_002925532.1 CDS mdlA NC_012759.1 370854 372626 D MG1655 equivalent: b0448; putative multidrug transporter membrane\ATP-binding components 370854..372626 Escherichia coli BW2952 7954791 YP_002925533.1 CDS mdlB NC_012759.1 372619 374400 D MG1655 equivalent: b0449; putative multidrug transporter membrane\ATP-binding components 372619..374400 Escherichia coli BW2952 7953716 YP_002925534.1 CDS glnK NC_012759.1 374581 374919 D indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 374581..374919 Escherichia coli BW2952 7953717 YP_002925535.1 CDS amtB NC_012759.1 374949 376235 D MG1655 equivalent: b0451; ammonium transporter 374949..376235 Escherichia coli BW2952 7954404 YP_002925536.1 CDS tesB NC_012759.1 376284 377144 R MG1655 equivalent: b0452; acyl-CoA thioesterase II complement(376284..377144) Escherichia coli BW2952 7952474 YP_002925537.1 CDS ybaY NC_012759.1 377362 377934 D MG1655 equivalent: b0453; putative outer membrane lipoprotein 377362..377934 Escherichia coli BW2952 7952417 YP_002925538.1 CDS ybaZ NC_012759.1 377965 378354 R MG1655 equivalent: b0454; putative methyltransferase complement(377965..378354) Escherichia coli BW2952 7955200 YP_002925539.1 CDS ybaA NC_012759.1 378655 379008 D MG1655 equivalent: b0456; hypothetical protein 378655..379008 Escherichia coli BW2952 7952170 YP_002925540.1 CDS ylaB NC_012759.1 379050 380600 R MG1655 equivalent: b0457; hypothetical protein complement(379050..380600) Escherichia coli BW2952 7952930 YP_002925541.1 CDS ylaC NC_012759.1 380764 381234 R MG1655 equivalent: b0458; putative inner membrane protein complement(380764..381234) Escherichia coli BW2952 7952663 YP_002925542.1 CDS maa NC_012759.1 381350 381901 R MG1655 equivalent: b0459; maltose O-acetyltransferase complement(381350..381901) Escherichia coli BW2952 7954986 YP_002925543.1 CDS hha NC_012759.1 382073 382291 R with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein complement(382073..382291) Escherichia coli BW2952 7954205 YP_002925544.1 CDS ybaJ NC_012759.1 382317 382691 R MG1655 equivalent: b0461; hypothetical protein complement(382317..382691) Escherichia coli BW2952 7954278 YP_002925545.1 CDS acrB NC_012759.1 383237 386386 R MG1655 equivalent: b0462; multidrug efflux system protein complement(383237..386386) Escherichia coli BW2952 7955337 YP_002925546.1 CDS acrA NC_012759.1 386409 387602 R MG1655 equivalent: b0463; multidrug efflux system complement(386409..387602) Escherichia coli BW2952 7954299 YP_002925547.1 CDS acrR NC_012759.1 387744 388391 D regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 387744..388391 Escherichia coli BW2952 7954297 YP_002925548.1 CDS kefA NC_012759.1 388519 391881 D small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 388519..391881 Escherichia coli BW2952 7953461 YP_002925549.1 CDS ybaM NC_012759.1 392093 392254 R MG1655 equivalent: b0466; hypothetical protein complement(392093..392254) Escherichia coli BW2952 7953666 YP_002925550.1 CDS priC NC_012759.1 392268 392795 R PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' complement(392268..392795) Escherichia coli BW2952 7955338 YP_002925551.1 CDS ybaN NC_012759.1 392865 393242 D MG1655 equivalent: b0468; hypothetical protein 392865..393242 Escherichia coli BW2952 7955765 YP_002925552.1 CDS apt NC_012759.1 393395 393946 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 393395..393946 Escherichia coli BW2952 7952699 YP_002925553.1 CDS dnaX NC_012759.1 394075 396006 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 394075..396006 Escherichia coli BW2952 7952419 YP_002925554.1 CDS ybaB NC_012759.1 396059 396388 D MG1655 equivalent: b0471; hypothetical protein 396059..396388 Escherichia coli BW2952 7953326 YP_002925555.1 CDS recR NC_012759.1 396388 396993 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 396388..396993 Escherichia coli BW2952 7952931 YP_002925556.1 CDS htpG NC_012759.1 397103 398977 D molecular chaperone; heat shock protein 90 397103..398977 Escherichia coli BW2952 7953775 YP_002925557.1 CDS adk NC_012759.1 399158 399802 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 399158..399802 Escherichia coli BW2952 7954282 YP_002925558.1 CDS hemH NC_012759.1 400038 401000 D protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 400038..401000 Escherichia coli BW2952 7952423 YP_002925559.1 CDS aes NC_012759.1 400997 401956 R MG1655 equivalent: b0476; acetyl esterase complement(400997..401956) Escherichia coli BW2952 7953573 YP_002925560.1 CDS gsk NC_012759.1 402108 403412 D MG1655 equivalent: b0477; inosine/guanosine kinase 402108..403412 Escherichia coli BW2952 7952396 YP_002925561.1 CDS ybaL NC_012759.1 403545 405221 R YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; putative cation:proton antiport protein complement(403545..405221) Escherichia coli BW2952 7954000 YP_002925562.1 CDS fsr NC_012759.1 405459 406679 R MG1655 equivalent: b0479; putative fosmidomycin efflux system complement(405459..406679) Escherichia coli BW2952 7955738 YP_002925563.1 CDS ushA NC_012759.1 406897 408549 D catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 406897..408549 Escherichia coli BW2952 7954912 YP_002925564.1 CDS ybaK NC_012759.1 408586 409065 R MG1655 equivalent: b0481; hypothetical protein complement(408586..409065) Escherichia coli BW2952 7952575 YP_002925565.1 CDS ybaP NC_012759.1 409269 410063 R MG1655 equivalent: b0482; hypothetical protein complement(409269..410063) Escherichia coli BW2952 7952171 YP_002925566.1 CDS ybaQ NC_012759.1 410201 410542 D MG1655 equivalent: b0483; putative DNA-binding transcriptional regulator 410201..410542 Escherichia coli BW2952 7952764 YP_002925567.1 CDS copA NC_012759.1 410858 413362 R MG1655 equivalent: b0484; copper exporting ATPase complement(410858..413362) Escherichia coli BW2952 7954792 YP_002925568.1 CDS ybaS NC_012759.1 413624 414556 D catalyzes the formation of glutamate from glutamine; glutaminase 413624..414556 Escherichia coli BW2952 7953097 YP_002925569.1 CDS ybaT NC_012759.1 414559 415851 D MG1655 equivalent: b0486; putative transporter 414559..415851 Escherichia coli BW2952 7954924 YP_002925570.1 CDS cueR NC_012759.1 415976 416383 D activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 415976..416383 Escherichia coli BW2952 7955679 YP_002925571.1 CDS ybbJ NC_012759.1 416384 416842 R MG1655 equivalent: b0488; hypothetical protein complement(416384..416842) Escherichia coli BW2952 7953388 YP_002925572.1 CDS qmcA NC_012759.1 416839 417756 R MG1655 equivalent: b0489; putative protease, membrane anchored complement(416839..417756) Escherichia coli BW2952 7952664 YP_002925573.1 CDS ybbL NC_012759.1 417902 418579 D MG1655 equivalent: b0490; putative ABC transporter ATP-binding protein YbbL 417902..418579 Escherichia coli BW2952 7955332 YP_002925574.1 CDS ybbM NC_012759.1 418566 419345 D MG1655 equivalent: b0491; putative inner membrane protein 418566..419345 Escherichia coli BW2952 7955721 YP_002925575.1 CDS ybbN NC_012759.1 419408 420262 R MG1655 equivalent: b0492; putative thioredoxin domain-containing protein complement(419408..420262) Escherichia coli BW2952 7955024 YP_002925576.1 CDS ybbO NC_012759.1 420323 421132 R MG1655 equivalent: b0493; short chain dehydrogenase complement(420323..421132) Escherichia coli BW2952 7955621 YP_002925577.1 CDS tesA NC_012759.1 421122 421748 R MG1655 equivalent: b0494; multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 complement(421122..421748) Escherichia coli BW2952 7955245 YP_002925578.1 CDS ybbA NC_012759.1 421716 422402 D MG1655 equivalent: b0495; putative ABC transporter ATP-binding protein YbbA 421716..422402 Escherichia coli BW2952 7954317 YP_002925579.1 CDS ybbP NC_012759.1 422399 424813 D MG1655 equivalent: b0496; putative inner membrane protein 422399..424813 Escherichia coli BW2952 7955722 YP_002925580.1 CDS rhsD NC_012759.1 425244 429524 D MG1655 equivalent: b0497; rhsD element protein 425244..429524 Escherichia coli BW2952 7955025 YP_002925581.1 CDS ybbC NC_012759.1 429564 429932 D MG1655 equivalent: b0498; hypothetical protein 429564..429932 Escherichia coli BW2952 7955952 YP_002925582.1 CDS ybbB NC_012759.1 432115 433209 R catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase complement(432115..433209) Escherichia coli BW2952 7955442 YP_002925583.1 CDS allS NC_012759.1 433278 434204 R activator of the allDC-ylbA operon involved in allantoin utilization; DNA-binding transcriptional activator AllS complement(433278..434204) Escherichia coli BW2952 7956200 YP_002925584.1 CDS allA NC_012759.1 434434 434916 D catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 434434..434916 Escherichia coli BW2952 7953394 YP_002925585.1 CDS allR NC_012759.1 434994 435809 D regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 434994..435809 Escherichia coli BW2952 7956260 YP_002925586.1 CDS gcl NC_012759.1 435899 437680 D catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 435899..437680 Escherichia coli BW2952 7953462 YP_002925587.1 CDS hyi NC_012759.1 437693 438469 D MG1655 equivalent: b0508; hydroxypyruvate isomerase 437693..438469 Escherichia coli BW2952 7953871 YP_002925588.1 CDS glxR NC_012759.1 438569 439447 D MG1655 equivalent: b0509; tartronate semialdehyde reductase, NADH-dependent 438569..439447 Escherichia coli BW2952 7953960 YP_002925589.1 CDS ybbW NC_012759.1 439616 441070 D MG1655 equivalent: b0511; allantoin permease 439616..441070 Escherichia coli BW2952 7956108 YP_002925590.1 CDS allB NC_012759.1 441130 442491 D Plays a crucial role on both purine and pyrimidine metabolism; allantoinase 441130..442491 Escherichia coli BW2952 7954633 YP_002925591.1 CDS ybbY NC_012759.1 442548 443849 D MG1655 equivalent: b0513; putative purine permease YbbY 442548..443849 Escherichia coli BW2952 7952453 YP_002925592.1 CDS glxK NC_012759.1 443871 445016 D MG1655 equivalent: b0514; glycerate kinase 443871..445016 Escherichia coli BW2952 7955747 YP_002925593.1 CDS ylbA NC_012759.1 445244 446029 R MG1655 equivalent: b0515; hypothetical protein complement(445244..446029) Escherichia coli BW2952 7953844 YP_002925594.1 CDS allC NC_012759.1 446040 447275 R allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase complement(446040..447275) Escherichia coli BW2952 7952765 YP_002925595.1 CDS allD NC_012759.1 447297 448346 R MG1655 equivalent: b0517; ureidoglycolate dehydrogenase complement(447297..448346) Escherichia coli BW2952 7952452 YP_002925596.1 CDS fdrA NC_012759.1 448663 450330 D multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 448663..450330 Escherichia coli BW2952 7956259 YP_002925597.1 CDS ylbF NC_012759.1 451610 452425 D MG1655 equivalent: b0520; hypothetical protein 451610..452425 Escherichia coli BW2952 7954610 YP_002925598.1 CDS ybcF NC_012759.1 452422 453315 D MG1655 equivalent: b0521; carbamate kinase 452422..453315 Escherichia coli BW2952 7952932 YP_002925599.1 CDS purK NC_012759.1 453510 454577 R With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit complement(453510..454577) Escherichia coli BW2952 7954674 YP_002925600.1 CDS purE NC_012759.1 454574 455083 R MG1655 equivalent: b0523; N5-carboxyaminoimidazole ribonucleotide mutase complement(454574..455083) Escherichia coli BW2952 7954331 YP_002925601.1 CDS lpxH NC_012759.1 455201 455923 R catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase complement(455201..455923) Escherichia coli BW2952 7954330 YP_002925602.1 CDS ppiB NC_012759.1 455926 456420 R MG1655 equivalent: b0525; peptidyl-prolyl cis-trans isomerase B complement(455926..456420) Escherichia coli BW2952 7956225 YP_002925603.1 CDS cysS NC_012759.1 456594 457979 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 456594..457979 Escherichia coli BW2952 7954483 YP_002925604.1 CDS ybcI NC_012759.1 458015 458536 R MG1655 equivalent: b0527; hypothetical protein complement(458015..458536) Escherichia coli BW2952 7953186 YP_002925605.1 CDS ybcJ NC_012759.1 458644 458856 R MG1655 equivalent: b0528; hypothetical protein complement(458644..458856) Escherichia coli BW2952 7952665 YP_002925606.1 CDS folD NC_012759.1 458858 459724 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(458858..459724) Escherichia coli BW2952 7955572 YP_002925607.1 CDS sfmA NC_012759.1 460195 460737 D MG1655 equivalent: b0530; putative fimbrial-like adhesin protein 460195..460737 Escherichia coli BW2952 7952559 YP_002925608.1 CDS sfmC NC_012759.1 460957 461649 D MG1655 equivalent: b0531; pilin chaperone, periplasmic 460957..461649 Escherichia coli BW2952 7954892 YP_002925609.1 CDS sfmD NC_012759.1 461680 464283 D MG1655 equivalent: b0532; putative outer membrane export usher protein 461680..464283 Escherichia coli BW2952 7954560 YP_002925610.1 CDS sfmH NC_012759.1 464319 465302 D MG1655 equivalent: b0533; putative fimbrial-like adhesin protein 464319..465302 Escherichia coli BW2952 7955196 YP_002925611.1 CDS sfmF NC_012759.1 465313 465828 D MG1655 equivalent: b0534; putative fimbrial protein 465313..465828 Escherichia coli BW2952 7954893 YP_002925612.1 CDS fimZ NC_012759.1 465831 466463 R activates the production of the major fimbrae protein FimA; transcriptional regulator FimZ complement(465831..466463) Escherichia coli BW2952 7954894 YP_002925613.1 CDS intD NC_012759.1 466798 467961 R MG1655 equivalent: b0537; DLP12 prophage; putative integrase complement(466798..467961) Escherichia coli BW2952 7952120 YP_002925614.1 CDS insE NC_012759.1 468816 469124 D MG1655 equivalent: b0540; IS3 element protein InsE 468816..469124 Escherichia coli BW2952 7953284 YP_002925615.1 CDS insF NC_012759.1 469121 469987 D MG1655 equivalent: b0541; IS3 element protein InsF 469121..469987 Escherichia coli BW2952 7954030 YP_002925616.1 CDS emrE NC_012759.1 470298 470630 D member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein 470298..470630 Escherichia coli BW2952 7954034 YP_002925617.1 CDS ybcK NC_012759.1 470885 472411 D MG1655 equivalent: b0544; DLP12 prophage; putative recombinase 470885..472411 Escherichia coli BW2952 7953280 YP_002925618.1 CDS ybcL NC_012759.1 472876 473427 D DLP12 prophage; similar to PEBP/RK1P protein family in eukaryotes that inhibits MEK phosphorylation by Raf-1; crystal structure suggests similar properties but exact function is unknown; putative kinase inhibitor 472876..473427 Escherichia coli BW2952 7953296 YP_002925619.1 CDS ybcM NC_012759.1 473437 474234 D MG1655 equivalent: b0546; DLP12 prophage; putative DNA-binding transcriptional regulator 473437..474234 Escherichia coli BW2952 7953285 YP_002925620.1 CDS ylcH NC_012759.1 474351 474452 D MG1655 equivalent: b4588; hypothetical protein 474351..474452 Escherichia coli BW2952 7953283 YP_002925621.1 CDS ybcN NC_012759.1 474449 474904 D DLP12 prophage; hypothetical protein 474449..474904 Escherichia coli BW2952 7953983 YP_002925622.1 CDS ninE NC_012759.1 474904 475074 D DLP12 prophage; conserved protein similar to phage 82 and lambda proteins; prophage protein NinE 474904..475074 Escherichia coli BW2952 7953292 YP_002925623.1 CDS ybcO NC_012759.1 475067 475357 D MG1655 equivalent: b0549; DLP12 prophage protein 475067..475357 Escherichia coli BW2952 7953276 YP_002925624.1 CDS rusA NC_012759.1 475354 475716 D DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 475354..475716 Escherichia coli BW2952 7953293 YP_002925625.1 CDS ylcG NC_012759.1 475713 475853 D MG1655 equivalent: b4509; DLP12 prophage protein 475713..475853 Escherichia coli BW2952 7953279 YP_002925626.1 CDS quuD NC_012759.1 475939 476322 D MG1655 equivalent: b0551; DLP12 prophage; putative antitermination protein 475939..476322 Escherichia coli BW2952 7953295 YP_002925627.1 CDS insH NC_012759.1 476720 477736 R MG1655 equivalent: b0552; IS5 transposase and trans-activator complement(476720..477736) Escherichia coli BW2952 7953282 YP_002925628.1 CDS essD NC_012759.1 479381 479596 D MG1655 equivalent: b0554; DLP12 prophage; putative phage lysis protein 479381..479596 Escherichia coli BW2952 7954037 YP_002925629.1 CDS arrD NC_012759.1 479596 480093 D MG1655 equivalent: b0555; DLP12 prophage; putative lysozyme 479596..480093 Escherichia coli BW2952 7953290 YP_002925630.1 CDS rzpD NC_012759.1 480090 480551 D MG1655 equivalent: b0556; DLP12 prophage; putative murein endopeptidase 480090..480551 Escherichia coli BW2952 7953288 YP_002925631.1 CDS rzoD NC_012759.1 480310 480492 D MG1655 equivalent: b4510; DLP12 prophage; putative lipoprotein 480310..480492 Escherichia coli BW2952 7953289 YP_002925632.1 CDS borD NC_012759.1 480583 480876 R MG1655 equivalent: b0557; DLP12 prophage; putative lipoprotein complement(480583..480876) Escherichia coli BW2952 7953287 YP_002925633.1 CDS ybcV NC_012759.1 481167 481577 R MG1655 equivalent: b0558; DLP12 prophage protein complement(481167..481577) Escherichia coli BW2952 7953286 YP_002925634.1 CDS ybcW NC_012759.1 481863 482069 D MG1655 equivalent: b0559; DLP12 prophage protein 481863..482069 Escherichia coli BW2952 7953291 YP_002925635.1 CDS ylcI NC_012759.1 482234 482428 R MG1655 equivalent: b4589; hypothetical protein complement(482234..482428) Escherichia coli BW2952 7953294 YP_002925636.1 CDS nohB NC_012759.1 482817 483362 D MG1655 equivalent: b0560; DLP12 prophage; DNA packaging protein 482817..483362 Escherichia coli BW2952 7953962 YP_002925637.1 CDS appY NC_012759.1 485664 486413 D MG1655 equivalent: b0564; DLP12 prophage; DNA-binding transcriptional activator 485664..486413 Escherichia coli BW2952 7953277 YP_002925638.1 CDS ompT NC_012759.1 486663 487616 R outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease complement(486663..487616) Escherichia coli BW2952 7953278 YP_002925639.1 CDS envY NC_012759.1 488130 488891 R MG1655 equivalent: b0566; DNA-binding transcriptional activator of porin biosynthesis complement(488130..488891) Escherichia coli BW2952 7952121 YP_002925640.1 CDS ybcH NC_012759.1 489074 489964 R MG1655 equivalent: b0567; hypothetical protein complement(489074..489964) Escherichia coli BW2952 7953392 YP_002925641.1 CDS nfrA NC_012759.1 489965 492937 R MG1655 equivalent: b0568; bacteriophage N4 receptor, outer membrane subunit complement(489965..492937) Escherichia coli BW2952 7955339 YP_002925642.1 CDS nfrB NC_012759.1 492924 495161 R MG1655 equivalent: b0569; bacteriophage N4 adsorption protein B complement(492924..495161) Escherichia coli BW2952 7952544 YP_002925643.1 CDS cusS NC_012759.1 495311 496753 R MG1655 equivalent: b0570; sensor kinase CusS complement(495311..496753) Escherichia coli BW2952 7952543 YP_002925644.1 CDS cusR NC_012759.1 496743 497426 R response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR complement(496743..497426) Escherichia coli BW2952 7956017 YP_002925645.1 CDS cusC NC_012759.1 497583 498956 D with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 497583..498956 Escherichia coli BW2952 7953350 YP_002925646.1 CDS cusF NC_012759.1 499114 499446 D MG1655 equivalent: b0573; copper-binding protein 499114..499446 Escherichia coli BW2952 7953100 YP_002925647.1 CDS cusB NC_012759.1 499462 500685 D with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 499462..500685 Escherichia coli BW2952 7954488 YP_002925648.1 CDS cusA NC_012759.1 500697 503840 D MG1655 equivalent: b0575; copper/silver efflux system, membrane component 500697..503840 Escherichia coli BW2952 7953099 YP_002925649.1 CDS pheP NC_012759.1 503942 505318 D MG1655 equivalent: b0576; phenylalanine transporter 503942..505318 Escherichia coli BW2952 7953098 YP_002925650.1 CDS ybdG NC_012759.1 505399 506646 R MG1655 equivalent: b0577; putative mechanosensitive channel complement(505399..506646) Escherichia coli BW2952 7954508 YP_002925651.1 CDS nfsB NC_012759.1 506754 507407 R catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase complement(506754..507407) Escherichia coli BW2952 7955135 YP_002925652.1 CDS ybdF NC_012759.1 507501 507869 R MG1655 equivalent: b0579; hypothetical protein complement(507501..507869) Escherichia coli BW2952 7953256 YP_002925653.1 CDS ybdJ NC_012759.1 507934 508182 R MG1655 equivalent: b0580; putative inner membrane protein complement(507934..508182) Escherichia coli BW2952 7952766 YP_002925654.1 CDS ybdK NC_012759.1 508248 509366 R ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase complement(508248..509366) Escherichia coli BW2952 7954987 YP_002925655.1 CDS hokE NC_012759.1 509819 509971 D MG1655 equivalent: b4415; toxic polypeptide, small 509819..509971 Escherichia coli BW2952 7953770 YP_002925656.1 CDS insL NC_012759.1 510048 511160 D MG1655 equivalent: b0582; IS186/IS421 transposase 510048..511160 Escherichia coli BW2952 7956159 YP_002925657.1 CDS entD NC_012759.1 511442 512071 R MG1655 equivalent: b0583; phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex complement(511442..512071) Escherichia coli BW2952 7954026 YP_002925658.1 CDS fepA NC_012759.1 512237 514477 R Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA complement(512237..514477) Escherichia coli BW2952 7954546 YP_002925659.1 CDS fes NC_012759.1 514798 515922 D MG1655 equivalent: b0585; enterobactin/ferric enterobactin esterase 514798..515922 Escherichia coli BW2952 7954013 YP_002925660.1 CDS ybdZ NC_012759.1 515925 516143 D MG1655 equivalent: b4511; hypothetical protein 515925..516143 Escherichia coli BW2952 7953528 YP_002925661.1 CDS entF NC_012759.1 516140 520021 D with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 516140..520021 Escherichia coli BW2952 7953070 YP_002925662.1 CDS fepE NC_012759.1 520237 521370 D part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 520237..521370 Escherichia coli BW2952 7953527 YP_002925663.1 CDS fepC NC_012759.1 521367 522182 R with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein complement(521367..522182) Escherichia coli BW2952 7955921 YP_002925664.1 CDS fepG NC_012759.1 522179 523171 R with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease complement(522179..523171) Escherichia coli BW2952 7954014 YP_002925665.1 CDS fepD NC_012759.1 523168 524172 R with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein complement(523168..524172) Escherichia coli BW2952 7954015 YP_002925666.1 CDS entS NC_012759.1 524283 525533 D protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 524283..525533 Escherichia coli BW2952 7954016 YP_002925667.1 CDS fepB NC_012759.1 525537 526493 R with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein complement(525537..526493) Escherichia coli BW2952 7955680 YP_002925668.1 CDS entC NC_012759.1 526868 528043 D MG1655 equivalent: b0593; isochorismate synthase 1 526868..528043 Escherichia coli BW2952 7954017 YP_002925669.1 CDS entE NC_012759.1 528053 529663 D bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 528053..529663 Escherichia coli BW2952 7954049 YP_002925670.1 CDS entB NC_012759.1 529677 530534 D MG1655 equivalent: b0595; isochorismatase 529677..530534 Escherichia coli BW2952 7952235 YP_002925671.1 CDS entA NC_012759.1 530534 531280 D catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 530534..531280 Escherichia coli BW2952 7954048 YP_002925672.1 CDS ybdB NC_012759.1 531283 531696 D MG1655 equivalent: b0597; hypothetical protein 531283..531696 Escherichia coli BW2952 7952233 YP_002925673.1 CDS cstA NC_012759.1 531877 533982 D MG1655 equivalent: b0598; carbon starvation protein 531877..533982 Escherichia coli BW2952 7952933 YP_002925674.1 CDS ybdD NC_012759.1 534165 534362 D MG1655 equivalent: b4512; hypothetical protein 534165..534362 Escherichia coli BW2952 7952596 YP_002925675.1 CDS ybdH NC_012759.1 534372 535460 R member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein complement(534372..535460) Escherichia coli BW2952 7953071 YP_002925676.1 CDS ybdL NC_012759.1 535569 536729 D catalyzes the transfer of an amino moiety; putative aminotransferase 535569..536729 Escherichia coli BW2952 7955221 YP_002925677.1 CDS ybdM NC_012759.1 536730 537359 R MG1655 equivalent: b0601; hypothetical protein complement(536730..537359) Escherichia coli BW2952 7954244 YP_002925678.1 CDS ybdN NC_012759.1 537332 538552 R MG1655 equivalent: b0602; hypothetical protein complement(537332..538552) Escherichia coli BW2952 7952767 YP_002925679.1 CDS ybdO NC_012759.1 538699 539601 R MG1655 equivalent: b0603; putative DNA-binding transcriptional regulator complement(538699..539601) Escherichia coli BW2952 7952768 YP_002925680.1 CDS dsbG NC_012759.1 539810 540556 R Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase complement(539810..540556) Escherichia coli BW2952 7954747 YP_002925681.1 CDS ahpC NC_012759.1 540928 541491 D with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase subunit C 540928..541491 Escherichia coli BW2952 7954489 YP_002925682.1 CDS ahpF NC_012759.1 541736 543301 D MG1655 equivalent: b0606; alkyl hydroperoxide reductase, F52a subunit, FAD/NAD(P)-binding 541736..543301 Escherichia coli BW2952 7952450 YP_002925683.1 CDS uspG NC_012759.1 543422 543850 R MG1655 equivalent: b0607; universal stress protein UP12 complement(543422..543850) Escherichia coli BW2952 7952451 YP_002925684.1 CDS ybdR NC_012759.1 544071 545309 D MG1655 equivalent: b0608; putative oxidoreductase, Zn-dependent and NAD(P)-binding 544071..545309 Escherichia coli BW2952 7956255 YP_002925685.1 CDS rnk NC_012759.1 545540 545950 R Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator complement(545540..545950) Escherichia coli BW2952 7955262 YP_002925686.1 CDS rna NC_012759.1 546180 546986 R MG1655 equivalent: b0611; ribonuclease I complement(546180..546986) Escherichia coli BW2952 7955922 YP_002925687.1 CDS citT NC_012759.1 547100 548563 R MG1655 equivalent: b0612; citrate:succinate antiporter complement(547100..548563) Escherichia coli BW2952 7955961 YP_002925688.1 CDS citG NC_012759.1 548614 549492 R catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase complement(548614..549492) Escherichia coli BW2952 7952644 YP_002925689.1 CDS citX NC_012759.1 549467 550018 R 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase complement(549467..550018) Escherichia coli BW2952 7956194 YP_002925690.1 CDS citF NC_012759.1 550022 551554 R MG1655 equivalent: b0615; citrate lyase, citrate-ACP transferase (alpha) subunit complement(550022..551554) Escherichia coli BW2952 7952489 YP_002925691.1 CDS citE NC_012759.1 551565 552473 R MG1655 equivalent: b0616; citrate lyase, citryl-ACP lyase (beta) subunit complement(551565..552473) Escherichia coli BW2952 7952641 YP_002925692.1 CDS citD NC_012759.1 552470 552766 R acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma complement(552470..552766) Escherichia coli BW2952 7952642 YP_002925693.1 CDS citC NC_012759.1 552781 553839 R MG1655 equivalent: b0618; citrate lyase synthetase complement(552781..553839) Escherichia coli BW2952 7952640 YP_002925694.1 CDS dpiB NC_012759.1 554218 555876 D MG1655 equivalent: b0619; sensory histidine kinase in two-component regulatory system with citB 554218..555876 Escherichia coli BW2952 7952639 YP_002925695.1 CDS dpiA NC_012759.1 555845 556525 D regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 555845..556525 Escherichia coli BW2952 7956014 YP_002925696.1 CDS dcuC NC_012759.1 556566 557951 R responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC complement(556566..557951) Escherichia coli BW2952 7953347 YP_002925697.1 CDS pagP NC_012759.1 558540 559100 D catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 558540..559100 Escherichia coli BW2952 7952476 YP_002925698.1 CDS cspE NC_012759.1 559275 559484 D member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 559275..559484 Escherichia coli BW2952 7954462 YP_002925699.1 CDS crcB NC_012759.1 559538 559921 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(559538..559921) Escherichia coli BW2952 7953463 YP_002925700.1 CDS tatE NC_012759.1 560930 561133 D TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein E 560930..561133 Escherichia coli BW2952 7955075 YP_002925701.1 CDS lipA NC_012759.1 561234 562199 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(561234..562199) Escherichia coli BW2952 7956109 YP_002925702.1 CDS ybeF NC_012759.1 562408 563361 R MG1655 equivalent: b0629; putative DNA-binding transcriptional regulator complement(562408..563361) Escherichia coli BW2952 7954147 YP_002925703.1 CDS lipB NC_012759.1 563620 564261 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(563620..564261) Escherichia coli BW2952 7954748 YP_002925704.1 CDS ybeD NC_012759.1 564362 564625 R MG1655 equivalent: b0631; hypothetical protein complement(564362..564625) Escherichia coli BW2952 7954159 YP_002925705.1 CDS dacA NC_012759.1 564735 565946 R penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase complement(564735..565946) Escherichia coli BW2952 7952769 YP_002925706.1 CDS rlpA NC_012759.1 566085 567173 R MG1655 equivalent: b0633; rare lipoprotein A complement(566085..567173) Escherichia coli BW2952 7953218 YP_002925707.1 CDS mrdB NC_012759.1 567184 568296 R MG1655 equivalent: b0634; cell wall shape-determining protein complement(567184..568296) Escherichia coli BW2952 7954267 YP_002925708.1 CDS mrdA NC_012759.1 568299 570200 R MG1655 equivalent: b0635; penicillin-binding protein 2 complement(568299..570200) Escherichia coli BW2952 7952619 YP_002925709.1 CDS ybeA NC_012759.1 570231 570698 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(570231..570698) Escherichia coli BW2952 7956177 YP_002925710.1 CDS ybeB NC_012759.1 570702 571019 R MG1655 equivalent: b0637; hypothetical protein complement(570702..571019) Escherichia coli BW2952 7952770 YP_002925711.1 CDS cobC NC_012759.1 571279 571890 R MG1655 equivalent: b0638; putative alpha-ribazole-5'-P phosphatase complement(571279..571890) Escherichia coli BW2952 7955340 YP_002925712.1 CDS nadD NC_012759.1 571914 572555 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase complement(571914..572555) Escherichia coli BW2952 7954635 YP_002925713.1 CDS holA NC_012759.1 572557 573588 R required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta complement(572557..573588) Escherichia coli BW2952 7954385 YP_002925714.1 CDS rlpB NC_012759.1 573588 574169 R rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB complement(573588..574169) Escherichia coli BW2952 7953323 YP_002925715.1 CDS leuS NC_012759.1 574184 576766 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(574184..576766) Escherichia coli BW2952 7954268 YP_002925716.1 CDS ybeL NC_012759.1 577001 577483 D MG1655 equivalent: b0643; hypothetical protein 577001..577483 Escherichia coli BW2952 7954132 YP_002925717.1 CDS ybeQ NC_012759.1 577553 578530 R MG1655 equivalent: b0644; hypothetical protein complement(577553..578530) Escherichia coli BW2952 7952934 YP_002925718.1 CDS ybeR NC_012759.1 578694 579401 D MG1655 equivalent: b0645; hypothetical protein 578694..579401 Escherichia coli BW2952 7952771 YP_002925719.1 CDS djlB NC_012759.1 579398 580825 D MG1655 equivalent: b0646; putative chaperone 579398..580825 Escherichia coli BW2952 7955443 YP_002925720.1 CDS ybeT NC_012759.1 580835 581389 R MG1655 equivalent: b0647; hypothetical protein complement(580835..581389) Escherichia coli BW2952 7954687 YP_002925721.1 CDS ybeU NC_012759.1 581491 582198 D MG1655 equivalent: b0648; putative tRNA ligase 581491..582198 Escherichia coli BW2952 7952748 YP_002925722.1 CDS djlC NC_012759.1 582195 583646 D MG1655 equivalent: b0649; Hsc56 co-chaperone of HscC 582195..583646 Escherichia coli BW2952 7955744 YP_002925723.1 CDS hscC NC_012759.1 583706 585376 R MG1655 equivalent: b0650; Hsp70 family chaperone Hsc62, binds to RpoD and inhibits transcription complement(583706..585376) Escherichia coli BW2952 7953923 YP_002925724.1 CDS rihA NC_012759.1 585460 586395 R Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 complement(585460..586395) Escherichia coli BW2952 7953925 YP_002925725.1 CDS gltL NC_012759.1 586513 587238 R MG1655 equivalent: b0652; glutamate and aspartate transporter subunit complement(586513..587238) Escherichia coli BW2952 7955966 YP_002925726.1 CDS gltK NC_012759.1 587238 587912 R MG1655 equivalent: b0653; glutamate and aspartate transporter subunit complement(587238..587912) Escherichia coli BW2952 7953814 YP_002925727.1 CDS gltJ NC_012759.1 587912 588652 R MG1655 equivalent: b0654; glutamate and aspartate transporter subunit complement(587912..588652) Escherichia coli BW2952 7953815 YP_002925728.1 CDS gltI NC_012759.1 588822 589730 R MG1655 equivalent: b0655; glutamate and aspartate transporter subunit complement(588822..589730) Escherichia coli BW2952 7953816 YP_002925729.1 CDS insH NC_012759.1 589980 590996 R MG1655 equivalent: b0656; IS5 transposase and trans-activator complement(589980..590996) Escherichia coli BW2952 7953817 YP_002925730.1 CDS lnt NC_012759.1 591326 592864 R Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase complement(591326..592864) Escherichia coli BW2952 7954038 YP_002925731.1 CDS ybeX NC_012759.1 592889 593767 R MG1655 equivalent: b0658; predicteed ion transport complement(592889..593767) Escherichia coli BW2952 7952490 YP_002925732.1 CDS ybeY NC_012759.1 593857 594324 R MG1655 equivalent: b0659; putative metalloprotease complement(593857..594324) Escherichia coli BW2952 7955758 YP_002925733.1 CDS ybeZ NC_012759.1 594321 595361 R MG1655 equivalent: b0660; hypothetical protein complement(594321..595361) Escherichia coli BW2952 7952772 YP_002925734.1 CDS miaB NC_012759.1 595514 596938 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(595514..596938) Escherichia coli BW2952 7955542 YP_002925735.1 CDS ubiF NC_012759.1 597084 598259 D catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 597084..598259 Escherichia coli BW2952 7954055 YP_002925736.1 CDS asnB NC_012759.1 599496 601160 R functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B complement(599496..601160) Escherichia coli BW2952 7952047 YP_002925737.1 CDS nagD NC_012759.1 601557 602309 R MG1655 equivalent: b0675; UMP phosphatase complement(601557..602309) Escherichia coli BW2952 7952508 YP_002925738.1 CDS nagC NC_012759.1 602357 603577 R MG1655 equivalent: b0676; DNA-binding transcriptional dual regulator complement(602357..603577) Escherichia coli BW2952 7956246 YP_002925739.1 CDS nagA NC_012759.1 603586 604734 R catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase complement(603586..604734) Escherichia coli BW2952 7953436 YP_002925740.1 CDS nagB NC_012759.1 604794 605594 R catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase complement(604794..605594) Escherichia coli BW2952 7954341 YP_002925741.1 CDS nagE NC_012759.1 605927 607873 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunit IIABC 605927..607873 Escherichia coli BW2952 7953802 YP_002925742.1 CDS glnS NC_012759.1 608076 609740 D catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 608076..609740 Escherichia coli BW2952 7953702 YP_002925743.1 CDS ybfM NC_012759.1 610317 611723 D MG1655 equivalent: b0681; putative outer membrane porin 610317..611723 Escherichia coli BW2952 7953834 YP_002925744.1 CDS ybfN NC_012759.1 611773 612099 D MG1655 equivalent: b0682; putative lipoprotein 611773..612099 Escherichia coli BW2952 7955206 YP_002925745.1 CDS fur NC_012759.1 612183 612629 R negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator complement(612183..612629) Escherichia coli BW2952 7955112 YP_002925746.1 CDS uof NC_012759.1 612622 612708 R MG1655 equivalent: b4637; ryhB-regulated fur leader peptide complement(612622..612708) Escherichia coli BW2952 7953427 YP_002925747.1 CDS fldA NC_012759.1 612918 613448 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA complement(612918..613448) Escherichia coli BW2952 7955996 YP_002925748.1 CDS ybfE NC_012759.1 613588 613881 R MG1655 equivalent: b0685; LexA regulated protein complement(613588..613881) Escherichia coli BW2952 7953609 YP_002925749.1 CDS ybfF NC_012759.1 614021 614785 R MG1655 equivalent: b0686; hypothetical protein complement(614021..614785) Escherichia coli BW2952 7954133 YP_002925750.1 CDS seqA NC_012759.1 614970 615515 D negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 614970..615515 Escherichia coli BW2952 7952773 YP_002925751.1 CDS pgm NC_012759.1 615541 617181 D catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 615541..617181 Escherichia coli BW2952 7955935 YP_002925752.1 CDS ybfP NC_012759.1 617395 617889 D MG1655 equivalent: b0689; hypothetical protein 617395..617889 Escherichia coli BW2952 7954531 YP_002925753.1 CDS potE NC_012759.1 618929 620248 R catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter complement(618929..620248) Escherichia coli BW2952 7955444 YP_002925754.1 CDS speF NC_012759.1 620245 622443 R MG1655 equivalent: b0693; ornithine decarboxylase complement(620245..622443) Escherichia coli BW2952 7955832 YP_002925755.1 CDS ybfK NC_012759.1 622566 622823 D MG1655 equivalent: b4590; hypothetical protein 622566..622823 Escherichia coli BW2952 7954429 YP_002925756.1 CDS kdpE NC_012759.1 623039 623716 R response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE complement(623039..623716) Escherichia coli BW2952 7953975 YP_002925757.1 CDS kdpD NC_012759.1 623713 626397 R sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD complement(623713..626397) Escherichia coli BW2952 7953354 YP_002925758.1 CDS kdpC NC_012759.1 626390 626962 R One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C complement(626390..626962) Escherichia coli BW2952 7953741 YP_002925759.1 CDS kdpB NC_012759.1 626971 629019 R One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B complement(626971..629019) Escherichia coli BW2952 7954575 YP_002925760.1 CDS kdpA NC_012759.1 629042 630715 R catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A complement(629042..630715) Escherichia coli BW2952 7954574 YP_002925761.1 CDS kdpF NC_012759.1 630715 630804 R one of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit F complement(630715..630804) Escherichia coli BW2952 7954573 YP_002925762.1 CDS ybfA NC_012759.1 631117 631323 D MG1655 equivalent: b0699; hypothetical protein 631117..631323 Escherichia coli BW2952 7954572 YP_002925763.1 CDS rhsC NC_012759.1 631566 635759 D MG1655 equivalent: b0700; rhsC element core protein RshC 631566..635759 Escherichia coli BW2952 7955445 YP_002925764.1 CDS ybfB NC_012759.1 635759 636085 D MG1655 equivalent: b0702; putative inner membrane protein 635759..636085 Escherichia coli BW2952 7955951 YP_002925765.1 CDS ybfC NC_012759.1 637633 638202 D MG1655 equivalent: b0704; hypothetical protein 637633..638202 Escherichia coli BW2952 7955026 YP_002925766.1 CDS ybfQ NC_012759.1 638428 638682 D MG1655 equivalent: b4514; putative transposase 638428..638682 Escherichia coli BW2952 7955446 YP_002925767.1 CDS ybfD NC_012759.1 640075 640836 D MG1655 equivalent: b0706; hypothetical protein 640075..640836 Escherichia coli BW2952 7955743 YP_002925768.1 CDS ybgA NC_012759.1 640984 641493 D MG1655 equivalent: b0707; hypothetical protein 640984..641493 Escherichia coli BW2952 7952935 YP_002925769.1 CDS phr NC_012759.1 641490 642908 D UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 641490..642908 Escherichia coli BW2952 7952936 YP_002925770.1 CDS ybgH NC_012759.1 643058 644539 R MG1655 equivalent: b0709; putative transporter complement(643058..644539) Escherichia coli BW2952 7953235 YP_002925771.1 CDS ybgI NC_012759.1 644810 645553 D MG1655 equivalent: b0710; putative hydrolase-oxidase 644810..645553 Escherichia coli BW2952 7955650 YP_002925772.1 CDS ybgJ NC_012759.1 645576 646232 D MG1655 equivalent: b0711; putative enzyme subunit 645576..646232 Escherichia coli BW2952 7952746 YP_002925773.1 CDS ybgK NC_012759.1 646226 647158 D MG1655 equivalent: b0712; putative enzyme subunit 646226..647158 Escherichia coli BW2952 7954858 YP_002925774.1 CDS ybgL NC_012759.1 647148 647882 D MG1655 equivalent: b0713; LamB/YcsF family protein 647148..647882 Escherichia coli BW2952 7954859 YP_002925775.1 CDS nei NC_012759.1 647918 648709 D 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity; endonuclease VIII 647918..648709 Escherichia coli BW2952 7955098 YP_002925776.1 CDS abrB NC_012759.1 648706 649752 R MG1655 equivalent: b0715; putative regulator complement(648706..649752) Escherichia coli BW2952 7953521 YP_002925777.1 CDS ybgO NC_012759.1 649904 650965 R MG1655 equivalent: b0716; putative fimbrial-like adhesin protein complement(649904..650965) Escherichia coli BW2952 7955558 YP_002925778.1 CDS ybgP NC_012759.1 650962 651690 R MG1655 equivalent: b0717; putative assembly protein complement(650962..651690) Escherichia coli BW2952 7954881 YP_002925779.1 CDS ybgQ NC_012759.1 651705 654152 R MG1655 equivalent: b0718; putative outer membrane protein complement(651705..654152) Escherichia coli BW2952 7954659 YP_002925780.1 CDS ybgD NC_012759.1 654212 654778 R MG1655 equivalent: b0719; putative fimbrial-like adhesin protein complement(654212..654778) Escherichia coli BW2952 7955210 YP_002925781.1 CDS gltA NC_012759.1 655168 656451 R type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase complement(655168..656451) Escherichia coli BW2952 7954882 YP_002925782.1 CDS sdhC NC_012759.1 657160 657549 D MG1655 equivalent: b0721; succinate dehydrogenase cytochrome b556 large membrane subunit 657160..657549 Escherichia coli BW2952 7952643 YP_002925783.1 CDS sdhD NC_012759.1 657543 657890 D MG1655 equivalent: b0722; succinate dehydrogenase cytochrome b556 small membrane subunit 657543..657890 Escherichia coli BW2952 7956078 YP_002925784.1 CDS sdhA NC_012759.1 657890 659656 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 657890..659656 Escherichia coli BW2952 7956079 YP_002925785.1 CDS sdhB NC_012759.1 659672 660388 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 659672..660388 Escherichia coli BW2952 7956077 YP_002925786.1 CDS sucA NC_012759.1 660689 663490 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 660689..663490 Escherichia coli BW2952 7956076 YP_002925787.1 CDS sucB NC_012759.1 663505 664722 D component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 663505..664722 Escherichia coli BW2952 7952269 YP_002925788.1 CDS sucC NC_012759.1 664997 666163 D catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 664997..666163 Escherichia coli BW2952 7953253 YP_002925789.1 CDS sucD NC_012759.1 666163 667032 D Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 666163..667032 Escherichia coli BW2952 7956082 YP_002925790.1 CDS mngR NC_012759.1 667136 667858 R regulates the succiny-lCoA synthetase operon; DNA-binding transcriptional repressor MngR complement(667136..667858) Escherichia coli BW2952 7956083 YP_002925791.1 CDS mngA NC_012759.1 667967 669943 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC 667967..669943 Escherichia coli BW2952 7953429 YP_002925792.1 CDS mngB NC_012759.1 669961 672594 D MG1655 equivalent: b0732; alpha-mannosidase 669961..672594 Escherichia coli BW2952 7953649 YP_002925793.1 CDS cydA NC_012759.1 673441 675009 D MG1655 equivalent: b0733; cytochrome d terminal oxidase, subunit I 673441..675009 Escherichia coli BW2952 7952460 YP_002925794.1 CDS cydB NC_012759.1 675025 676164 D MG1655 equivalent: b0734; cytochrome d terminal oxidase, subunit II 675025..676164 Escherichia coli BW2952 7953194 YP_002925795.1 CDS ybgT NC_012759.1 676179 676292 D MG1655 equivalent: b4515; hypothetical protein 676179..676292 Escherichia coli BW2952 7953195 YP_002925796.1 CDS ybgE NC_012759.1 676292 676585 D MG1655 equivalent: b0735; hypothetical protein 676292..676585 Escherichia coli BW2952 7953072 YP_002925797.1 CDS ybgC NC_012759.1 676735 677139 D catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase YbgC 676735..677139 Escherichia coli BW2952 7952700 YP_002925798.1 CDS tolQ NC_012759.1 677136 677828 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 677136..677828 Escherichia coli BW2952 7954611 YP_002925799.1 CDS tolR NC_012759.1 677832 678260 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 677832..678260 Escherichia coli BW2952 7954233 YP_002925800.1 CDS tolA NC_012759.1 678325 679590 D inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 678325..679590 Escherichia coli BW2952 7954234 YP_002925801.1 CDS tolB NC_012759.1 679723 681015 D forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 679723..681015 Escherichia coli BW2952 7954222 YP_002925802.1 CDS pal NC_012759.1 681050 681571 D MG1655 equivalent: b0741; peptidoglycan-associated outer membrane lipoprotein 681050..681571 Escherichia coli BW2952 7954494 YP_002925803.1 CDS ybgF NC_012759.1 681581 682372 D periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 681581..682372 Escherichia coli BW2952 7954478 YP_002925804.1 CDS nadA NC_012759.1 684276 685319 D 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 684276..685319 Escherichia coli BW2952 7952129 YP_002925805.1 CDS pnuC NC_012759.1 685357 686076 D MG1655 equivalent: b0751; putative nicotinamide mononucleotide transporter 685357..686076 Escherichia coli BW2952 7955888 YP_002925806.1 CDS zitB NC_012759.1 686073 687014 R involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB complement(686073..687014) Escherichia coli BW2952 7955182 YP_002925807.1 CDS ybgS NC_012759.1 687128 687508 R MG1655 equivalent: b0753; hypothetical protein complement(687128..687508) Escherichia coli BW2952 7956282 YP_002925808.1 CDS aroG NC_012759.1 687824 688876 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 687824..688876 Escherichia coli BW2952 7952774 YP_002925809.1 CDS gpmA NC_012759.1 689034 689786 R 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase complement(689034..689786) Escherichia coli BW2952 7952297 YP_002925810.1 CDS galM NC_012759.1 689988 691028 R catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase complement(689988..691028) Escherichia coli BW2952 7954536 YP_002925811.1 CDS galK NC_012759.1 691022 692170 R catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase complement(691022..692170) Escherichia coli BW2952 7953761 YP_002925812.1 CDS galT NC_012759.1 692174 693220 R catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase complement(692174..693220) Escherichia coli BW2952 7953758 YP_002925813.1 CDS galE NC_012759.1 693230 694246 R MG1655 equivalent: b0759; UDP-galactose-4-epimerase complement(693230..694246) Escherichia coli BW2952 7953762 YP_002925814.1 CDS modF NC_012759.1 694507 695979 R contains 2 ATP-binding cassettes; involved in the transport of molybdenum; putative molybdenum transport ATP-binding protein ModF complement(694507..695979) Escherichia coli BW2952 7956232 YP_002925815.1 CDS modE NC_012759.1 696047 696835 R represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE complement(696047..696835) Escherichia coli BW2952 7953701 YP_002925816.1 CDS ybhT NC_012759.1 696964 697113 D MG1655 equivalent: b0762; hypothetical protein 696964..697113 Escherichia coli BW2952 7953404 YP_002925817.1 CDS modA NC_012759.1 697280 698053 D with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 697280..698053 Escherichia coli BW2952 7955448 YP_002925818.1 CDS modB NC_012759.1 698053 698742 D part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 698053..698742 Escherichia coli BW2952 7954283 YP_002925819.1 CDS modC NC_012759.1 698745 699803 D Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 698745..699803 Escherichia coli BW2952 7954284 YP_002925820.1 CDS ybhA NC_012759.1 699804 700622 R YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase complement(699804..700622) Escherichia coli BW2952 7954285 YP_002925821.1 CDS pgl NC_012759.1 700777 701772 D catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 700777..701772 Escherichia coli BW2952 7954950 YP_002925822.1 CDS ybhD NC_012759.1 701813 702766 R MG1655 equivalent: b0768; putative DNA-binding transcriptional regulator complement(701813..702766) Escherichia coli BW2952 7952380 YP_002925823.1 CDS ybhH NC_012759.1 702950 704002 D MG1655 equivalent: b0769; hypothetical protein 702950..704002 Escherichia coli BW2952 7954749 YP_002925824.1 CDS ybhI NC_012759.1 704078 705511 D MG1655 equivalent: b0770; putative transporter 704078..705511 Escherichia coli BW2952 7952937 YP_002925825.1 CDS ybhJ NC_012759.1 705694 707955 D MG1655 equivalent: b0771; hypothetical protein 705694..707955 Escherichia coli BW2952 7955681 YP_002925826.1 CDS ybhC NC_012759.1 708189 709472 R outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family; putative pectinesterase complement(708189..709472) Escherichia coli BW2952 7954947 YP_002925827.1 CDS ybhB NC_012759.1 709624 710100 R YbhB; similar to rat and human kinase inhibitory proteins; putative kinase inhibitor protein complement(709624..710100) Escherichia coli BW2952 7955269 YP_002925828.1 CDS bioA NC_012759.1 710159 711448 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase complement(710159..711448) Escherichia coli BW2952 7955097 YP_002925829.1 CDS bioB NC_012759.1 711535 712575 D MG1655 equivalent: b0775; biotin synthase 711535..712575 Escherichia coli BW2952 7952382 YP_002925830.1 CDS bioF NC_012759.1 712572 713726 D catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 712572..713726 Escherichia coli BW2952 7952582 YP_002925831.1 CDS bioC NC_012759.1 713713 714468 D putative methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC 713713..714468 Escherichia coli BW2952 7952386 YP_002925832.1 CDS bioD NC_012759.1 714461 715138 D DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 714461..715138 Escherichia coli BW2952 7955149 YP_002925833.1 CDS ybhU NC_012759.1 715305 715442 R MG1655 equivalent: b4591; hypothetical protein complement(715305..715442) Escherichia coli BW2952 7953241 YP_002925834.1 CDS uvrB NC_012759.1 715717 717738 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 715717..717738 Escherichia coli BW2952 7953963 YP_002925835.1 CDS ybhK NC_012759.1 717930 718838 R MG1655 equivalent: b0780; putative transferase with NAD(P)-binding Rossmann-fold domain complement(717930..718838) Escherichia coli BW2952 7953537 YP_002925836.1 CDS moaA NC_012759.1 719235 720224 D together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 719235..720224 Escherichia coli BW2952 7955643 YP_002925837.1 CDS moaB NC_012759.1 720246 720758 D MG1655 equivalent: b0782; molybdopterin biosynthesis protein B 720246..720758 Escherichia coli BW2952 7954288 YP_002925838.1 CDS moaC NC_012759.1 720761 721246 D MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 720761..721246 Escherichia coli BW2952 7954289 YP_002925839.1 CDS moaD NC_012759.1 721239 721484 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 721239..721484 Escherichia coli BW2952 7954290 YP_002925840.1 CDS moaE NC_012759.1 721486 721938 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 721486..721938 Escherichia coli BW2952 7954293 YP_002925841.1 CDS ybhL NC_012759.1 722075 722779 D MG1655 equivalent: b0786; putative inner membrane protein 722075..722779 Escherichia coli BW2952 7954292 YP_002925842.1 CDS ybhM NC_012759.1 722984 723697 D MG1655 equivalent: b0787; hypothetical protein 722984..723697 Escherichia coli BW2952 7955027 YP_002925843.1 CDS ybhN NC_012759.1 723733 724689 R MG1655 equivalent: b0788; hypothetical protein complement(723733..724689) Escherichia coli BW2952 7952701 YP_002925844.1 CDS ybhO NC_012759.1 724689 725930 R MG1655 equivalent: b0789; cardiolipin synthase 2 complement(724689..725930) Escherichia coli BW2952 7952666 YP_002925845.1 CDS ybhP NC_012759.1 725927 726688 R MG1655 equivalent: b0790; putative DNase complement(725927..726688) Escherichia coli BW2952 7952609 YP_002925846.1 CDS ybhQ NC_012759.1 726821 727231 D MG1655 equivalent: b0791; putative inner membrane protein 726821..727231 Escherichia coli BW2952 7954825 YP_002925847.1 CDS ybhR NC_012759.1 727193 728299 R MG1655 equivalent: b0792; putative transporter subunit: membrane component of ABC superfamily complement(727193..728299) Escherichia coli BW2952 7955028 YP_002925848.1 CDS ybhS NC_012759.1 728310 729443 R MG1655 equivalent: b0793; putative transporter subunit: membrane component of ABC superfamily complement(728310..729443) Escherichia coli BW2952 7955726 YP_002925849.1 CDS ybhF NC_012759.1 729436 731172 R MG1655 equivalent: b0794; fused putative transporter subunits of ABC superfamily: ATP-binding components complement(729436..731172) Escherichia coli BW2952 7955727 YP_002925850.1 CDS ybhG NC_012759.1 731165 732163 R MG1655 equivalent: b0795; hypothetical protein complement(731165..732163) Escherichia coli BW2952 7953730 YP_002925851.1 CDS ybiH NC_012759.1 732163 732834 R MG1655 equivalent: b0796; putative DNA-binding transcriptional regulator complement(732163..732834) Escherichia coli BW2952 7955138 YP_002925852.1 CDS rhlE NC_012759.1 733063 734427 D this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 733063..734427 Escherichia coli BW2952 7954750 YP_002925853.1 CDS ybiA NC_012759.1 734659 735141 R MG1655 equivalent: b0798; hypothetical protein complement(734659..735141) Escherichia coli BW2952 7955982 YP_002925854.1 CDS dinG NC_012759.1 735261 737411 D helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 735261..737411 Escherichia coli BW2952 7952775 YP_002925855.1 CDS ybiB NC_012759.1 737439 738401 D MG1655 equivalent: b0800; glycosyl transferase family protein 737439..738401 Escherichia coli BW2952 7952529 YP_002925856.1 CDS ybiC NC_012759.1 738542 739627 D MG1655 equivalent: b0801; hypothetical protein 738542..739627 Escherichia coli BW2952 7955644 YP_002925857.1 CDS ybiJ NC_012759.1 739856 740116 R MG1655 equivalent: b0802; hypothetical protein complement(739856..740116) Escherichia coli BW2952 7954714 YP_002925858.1 CDS ybiI NC_012759.1 740381 740647 R MG1655 equivalent: b0803; hypothetical protein complement(740381..740647) Escherichia coli BW2952 7955341 YP_002925859.1 CDS ybiX NC_012759.1 740721 741398 R MG1655 equivalent: b0804; putative hydroxylase complement(740721..741398) Escherichia coli BW2952 7952776 YP_002925860.1 CDS fiu NC_012759.1 741440 743722 R Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu complement(741440..743722) Escherichia coli BW2952 7952777 YP_002925861.1 CDS ybiM NC_012759.1 743987 744247 R MG1655 equivalent: b0806; hypothetical protein complement(743987..744247) Escherichia coli BW2952 7955087 YP_002925862.1 CDS rlmF NC_012759.1 744523 745449 D MG1655 equivalent: b0807; putative SAM-dependent methyltransferase 744523..745449 Escherichia coli BW2952 7955342 YP_002925863.1 CDS ybiO NC_012759.1 745446 747671 R MG1655 equivalent: b0808; hypothetical protein complement(745446..747671) Escherichia coli BW2952 7955583 YP_002925864.1 CDS glnQ NC_012759.1 747932 748654 R similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein complement(747932..748654) Escherichia coli BW2952 7955136 YP_002925865.1 CDS glnP NC_012759.1 748651 749310 R similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease complement(748651..749310) Escherichia coli BW2952 7953828 YP_002925866.1 CDS glnH NC_012759.1 749449 750195 R similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein complement(749449..750195) Escherichia coli BW2952 7953829 YP_002925867.1 CDS dps NC_012759.1 750599 751102 R binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps complement(750599..751102) Escherichia coli BW2952 7953830 YP_002925868.1 CDS rhtA NC_012759.1 751401 752288 R MG1655 equivalent: b0813; threonine and homoserine efflux system complement(751401..752288) Escherichia coli BW2952 7953562 YP_002925869.1 CDS ompX NC_012759.1 752641 753156 D OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 752641..753156 Escherichia coli BW2952 7956143 YP_002925870.1 CDS ybiP NC_012759.1 753205 754788 R MG1655 equivalent: b0815; putative hydrolase, inner membrane complement(753205..754788) Escherichia coli BW2952 7954447 YP_002925871.1 CDS yliL NC_012759.1 754862 755131 D MG1655 equivalent: b0816; hypothetical protein 754862..755131 Escherichia coli BW2952 7954977 YP_002925872.1 CDS mntR NC_012759.1 755374 755841 D Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 755374..755841 Escherichia coli BW2952 7952078 YP_002925873.1 CDS ybiR NC_012759.1 755838 756956 D MG1655 equivalent: b0818; putative transporter 755838..756956 Escherichia coli BW2952 7953445 YP_002925874.1 CDS ybiS NC_012759.1 757015 757935 R MG1655 equivalent: b0819; hypothetical protein complement(757015..757935) Escherichia coli BW2952 7955682 YP_002925875.1 CDS ybiT NC_012759.1 758154 759746 D MG1655 equivalent: b0820; fused putative transporter subunits of ABC superfamily: ATP-binding components 758154..759746 Escherichia coli BW2952 7952778 YP_002925876.1 CDS ybiU NC_012759.1 759987 761252 R MG1655 equivalent: b0821; hypothetical protein complement(759987..761252) Escherichia coli BW2952 7953732 YP_002925877.1 CDS ybiV NC_012759.1 761404 762219 R MG1655 equivalent: b0822; putative hydrolase complement(761404..762219) Escherichia coli BW2952 7955343 YP_002925878.1 CDS ybiW NC_012759.1 762365 764797 R MG1655 equivalent: b0823; putative pyruvate formate lyase complement(762365..764797) Escherichia coli BW2952 7954951 YP_002925879.1 CDS ybiY NC_012759.1 764803 765729 R MG1655 equivalent: b0824; putative pyruvate formate lyase activating enzyme complement(764803..765729) Escherichia coli BW2952 7955550 YP_002925880.1 CDS fsaA NC_012759.1 765833 766495 D similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 765833..766495 Escherichia coli BW2952 7955551 YP_002925881.1 CDS moeB NC_012759.1 766571 767320 R ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB complement(766571..767320) Escherichia coli BW2952 7953635 YP_002925882.1 CDS moeA NC_012759.1 767320 768555 R is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA complement(767320..768555) Escherichia coli BW2952 7954291 YP_002925883.1 CDS iaaA NC_012759.1 768759 769724 D MG1655 equivalent: b0828; L-asparaginase 768759..769724 Escherichia coli BW2952 7954287 YP_002925884.1 CDS gsiA NC_012759.1 769711 771582 D with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 769711..771582 Escherichia coli BW2952 7954120 YP_002925885.1 CDS gsiB NC_012759.1 771602 773140 D MG1655 equivalent: b0830; putative peptide transporter subunit: periplasmic-binding component of ABC superfamily 771602..773140 Escherichia coli BW2952 7953722 YP_002925886.1 CDS gsiC NC_012759.1 773158 774078 D MG1655 equivalent: b0831; putative peptide transporter subunit: membrane component of ABC superfamily 773158..774078 Escherichia coli BW2952 7955295 YP_002925887.1 CDS gsiD NC_012759.1 774081 774992 D MG1655 equivalent: b0832; putative peptide transporter subunit: membrane component of ABC superfamily 774081..774992 Escherichia coli BW2952 7955293 YP_002925888.1 CDS yliE NC_012759.1 775170 777518 D MG1655 equivalent: b0833; hypothetical protein 775170..777518 Escherichia coli BW2952 7955294 YP_002925889.1 CDS yliF NC_012759.1 777526 778854 D MG1655 equivalent: b0834; putative diguanylate cyclase 777526..778854 Escherichia coli BW2952 7952702 YP_002925890.1 CDS rimO NC_012759.1 778901 780226 R catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase complement(778901..780226) Escherichia coli BW2952 7954727 YP_002925891.1 CDS bssR NC_012759.1 780439 780822 D BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 780439..780822 Escherichia coli BW2952 7955581 YP_002925892.1 CDS yliI NC_012759.1 780933 782048 D MG1655 equivalent: b0837; putative dehydrogenase 780933..782048 Escherichia coli BW2952 7952938 YP_002925893.1 CDS yliJ NC_012759.1 782045 782671 R MG1655 equivalent: b0838; putative glutathione S-transferase complement(782045..782671) Escherichia coli BW2952 7954715 YP_002925894.1 CDS dacC NC_012759.1 782918 784120 D penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 782918..784120 Escherichia coli BW2952 7954926 YP_002925895.1 CDS deoR NC_012759.1 784167 784925 R MG1655 equivalent: b0840; DNA-binding transcriptional repressor DeoR complement(784167..784925) Escherichia coli BW2952 7953219 YP_002925896.1 CDS ybjG NC_012759.1 784983 785579 R MG1655 equivalent: b0841; UDP pyrophosphate phosphatase complement(784983..785579) Escherichia coli BW2952 7953449 YP_002925897.1 CDS cmr NC_012759.1 785864 787096 D MG1655 equivalent: b0842; multidrug efflux system protein 785864..787096 Escherichia coli BW2952 7956248 YP_002925898.1 CDS ybjH NC_012759.1 787137 787421 R MG1655 equivalent: b0843; hypothetical protein complement(787137..787421) Escherichia coli BW2952 7954301 YP_002925899.1 CDS ybjI NC_012759.1 787507 788322 R MG1655 equivalent: b0844; hypothetical protein complement(787507..788322) Escherichia coli BW2952 7955344 YP_002925900.1 CDS ybjJ NC_012759.1 788322 789530 R MG1655 equivalent: b0845; putative transporter complement(788322..789530) Escherichia coli BW2952 7952779 YP_002925901.1 CDS ybjK NC_012759.1 789614 790150 D MG1655 equivalent: b0846; putative DNA-binding transcriptional regulator 789614..790150 Escherichia coli BW2952 7955651 YP_002925902.1 CDS ybjL NC_012759.1 790325 792010 R MG1655 equivalent: b0847; hypothetical protein complement(790325..792010) Escherichia coli BW2952 7952079 YP_002925903.1 CDS ybjM NC_012759.1 792280 792657 D MG1655 equivalent: b0848; putative inner membrane protein 792280..792657 Escherichia coli BW2952 7955652 YP_002925904.1 CDS grxA NC_012759.1 792687 792944 R functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin complement(792687..792944) Escherichia coli BW2952 7955029 YP_002925905.1 CDS ybjC NC_012759.1 793104 793391 D YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 793104..793391 Escherichia coli BW2952 7953835 YP_002925906.1 CDS nfsA NC_012759.1 793375 794097 D NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 793375..794097 Escherichia coli BW2952 7955030 YP_002925907.1 CDS rimK NC_012759.1 794158 795060 D responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 794158..795060 Escherichia coli BW2952 7954405 YP_002925908.1 CDS ybjN NC_012759.1 795148 795624 D MG1655 equivalent: b0853; putative oxidoreductase 795148..795624 Escherichia coli BW2952 7955974 YP_002925909.1 CDS potF NC_012759.1 795975 797087 D MG1655 equivalent: b0854; putrescine ABC transporter periplasmic-binding protein 795975..797087 Escherichia coli BW2952 7955231 YP_002925910.1 CDS potG NC_012759.1 797182 798315 D part of the PotFGHI ATP-dependent putrescine transporter; putrescine ABC transporter ATP-binding protein 797182..798315 Escherichia coli BW2952 7955831 YP_002925911.1 CDS potH NC_012759.1 798325 799278 D MG1655 equivalent: b0856; putrescine ABC transporter membrane protein 798325..799278 Escherichia coli BW2952 7955828 YP_002925912.1 CDS potI NC_012759.1 799275 800120 D MG1655 equivalent: b0857; putrescine ABC transporter membrane protein 799275..800120 Escherichia coli BW2952 7955829 YP_002925913.1 CDS ybjO NC_012759.1 800180 800668 D MG1655 equivalent: b0858; putative inner membrane protein 800180..800668 Escherichia coli BW2952 7955830 YP_002925914.1 CDS rumB NC_012759.1 800709 801836 D RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 800709..801836 Escherichia coli BW2952 7955031 YP_002925915.1 CDS artJ NC_012759.1 802035 802766 R MG1655 equivalent: b0860; arginine transporter subunit complement(802035..802766) Escherichia coli BW2952 7952243 YP_002925916.1 CDS artM NC_012759.1 803057 803725 R with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM complement(803057..803725) Escherichia coli BW2952 7952495 YP_002925917.1 CDS artQ NC_012759.1 803725 804441 R with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ complement(803725..804441) Escherichia coli BW2952 7952496 YP_002925918.1 CDS artI NC_012759.1 804448 805179 R MG1655 equivalent: b0863; arginine transporter subunit complement(804448..805179) Escherichia coli BW2952 7952497 YP_002925919.1 CDS artP NC_012759.1 805197 805925 R With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit complement(805197..805925) Escherichia coli BW2952 7952498 YP_002925920.1 CDS ybjP NC_012759.1 806143 806658 R induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; putative lipoprotein complement(806143..806658) Escherichia coli BW2952 7952499 YP_002925921.1 CDS ybjQ NC_012759.1 806784 807107 D MG1655 equivalent: b0866; hypothetical protein 806784..807107 Escherichia coli BW2952 7955105 YP_002925922.1 CDS amiD NC_012759.1 807104 807934 D MG1655 equivalent: b0867; putative amidase and lipoprotein 807104..807934 Escherichia coli BW2952 7952939 YP_002925923.1 CDS ybjS NC_012759.1 807931 808944 R MG1655 equivalent: b0868; putative NAD(P)H-binding oxidoreductase with NAD(P)-binding Rossmann-fold domain complement(807931..808944) Escherichia coli BW2952 7954637 YP_002925924.1 CDS ybjT NC_012759.1 809043 810473 R MG1655 equivalent: b0869; hypothetical protein complement(809043..810473) Escherichia coli BW2952 7955181 YP_002925925.1 CDS ltaE NC_012759.1 810484 811485 R low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase complement(810484..811485) Escherichia coli BW2952 7953080 YP_002925926.1 CDS poxB NC_012759.1 811522 813240 R catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase complement(811522..813240) Escherichia coli BW2952 7954109 YP_002925927.1 CDS hcr NC_012759.1 813373 814341 R MG1655 equivalent: b0872; HCP oxidoreductase complement(813373..814341) Escherichia coli BW2952 7955844 YP_002925928.1 CDS hcp NC_012759.1 814353 816005 R catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase complement(814353..816005) Escherichia coli BW2952 7953888 YP_002925929.1 CDS ybjE NC_012759.1 816149 817048 R MG1655 equivalent: b0874; putative transporter complement(816149..817048) Escherichia coli BW2952 7953933 YP_002925930.1 CDS aqpZ NC_012759.1 817543 818238 R porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z complement(817543..818238) Escherichia coli BW2952 7955653 YP_002925931.1 CDS ybjD NC_012759.1 818664 820322 D MG1655 equivalent: b0876; hypothetical protein 818664..820322 Escherichia coli BW2952 7952491 YP_002925932.1 CDS ybjX NC_012759.1 820319 821311 R MG1655 equivalent: b0877; hypothetical protein complement(820319..821311) Escherichia coli BW2952 7953088 YP_002925933.1 CDS macA NC_012759.1 821426 822541 D confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 821426..822541 Escherichia coli BW2952 7952780 YP_002925934.1 CDS macB NC_012759.1 822538 824484 D with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease 822538..824484 Escherichia coli BW2952 7954190 YP_002925935.1 CDS cspD NC_012759.1 824557 824781 R inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible; stationary phase/starvation inducible regulatory protein CspD complement(824557..824781) Escherichia coli BW2952 7953694 YP_002925936.1 CDS clpS NC_012759.1 825104 825424 D involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 825104..825424 Escherichia coli BW2952 7952654 YP_002925937.1 CDS clpA NC_012759.1 825455 827731 D ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 825455..827731 Escherichia coli BW2952 7955931 YP_002925938.1 CDS infA NC_012759.1 828416 828634 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(828416..828634) Escherichia coli BW2952 7952048 YP_002925939.1 CDS aat NC_012759.1 828919 829623 R leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase complement(828919..829623) Escherichia coli BW2952 7956176 YP_002925940.1 CDS cydC NC_012759.1 829665 831386 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(829665..831386) Escherichia coli BW2952 7954131 YP_002925941.1 CDS cydD NC_012759.1 831387 833153 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(831387..833153) Escherichia coli BW2952 7953668 YP_002925942.1 CDS trxB NC_012759.1 833276 834241 R catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase complement(833276..834241) Escherichia coli BW2952 7953669 YP_002925943.1 CDS lrp NC_012759.1 834786 835280 D mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 834786..835280 Escherichia coli BW2952 7956136 YP_002925944.1 CDS ftsK NC_012759.1 835415 839404 D DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 835415..839404 Escherichia coli BW2952 7953434 YP_002925945.1 CDS lolA NC_012759.1 839563 840174 D participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 839563..840174 Escherichia coli BW2952 7953339 YP_002925946.1 CDS rarA NC_012759.1 840185 841528 D MG1655 equivalent: b0892; recombination factor protein RarA 840185..841528 Escherichia coli BW2952 7952626 YP_002925947.1 CDS serS NC_012759.1 841619 842911 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 841619..842911 Escherichia coli BW2952 7955916 YP_002925948.1 CDS dmsA NC_012759.1 843150 845594 D MG1655 equivalent: b0894; dimethyl sulfoxide reductase, anaerobic subunit A 843150..845594 Escherichia coli BW2952 7956036 YP_002925949.1 CDS dmsB NC_012759.1 845605 846222 D MG1655 equivalent: b0895; dimethyl sulfoxide reductase, anaerobic subunit B 845605..846222 Escherichia coli BW2952 7953261 YP_002925950.1 CDS dmsC NC_012759.1 846224 847087 D MG1655 equivalent: b0896; dimethyl sulfoxide reductase, anaerobic subunit C 846224..847087 Escherichia coli BW2952 7953262 YP_002925951.1 CDS ycaC NC_012759.1 847122 847748 R MG1655 equivalent: b0897; putative hydrolase complement(847122..847748) Escherichia coli BW2952 7953263 YP_002925952.1 CDS ycaD NC_012759.1 848062 849210 D MG1655 equivalent: b0898; putative MFS family transporter protein 848062..849210 Escherichia coli BW2952 7954952 YP_002925953.1 CDS ycaM NC_012759.1 849420 850850 D MG1655 equivalent: b0899; putative transporter 849420..850850 Escherichia coli BW2952 7955683 YP_002925954.1 CDS ycaN NC_012759.1 850851 851759 R MG1655 equivalent: b0900; putative DNA-binding transcriptional regulator complement(850851..851759) Escherichia coli BW2952 7955684 YP_002925955.1 CDS ycaK NC_012759.1 851859 852449 D MG1655 equivalent: b0901; hypothetical protein 851859..852449 Escherichia coli BW2952 7954751 YP_002925956.1 CDS pflA NC_012759.1 852531 853271 R activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 complement(852531..853271) Escherichia coli BW2952 7952940 YP_002925957.1 CDS pflB NC_012759.1 853463 855745 R MG1655 equivalent: b0903; pyruvate formate lyase I complement(853463..855745) Escherichia coli BW2952 7955847 YP_002925958.1 CDS focA NC_012759.1 855800 856657 R MG1655 equivalent: b0904; formate transporter complement(855800..856657) Escherichia coli BW2952 7955848 YP_002925959.1 CDS ycaO NC_012759.1 857063 858823 R MG1655 equivalent: b0905; hypothetical protein complement(857063..858823) Escherichia coli BW2952 7953626 YP_002925960.1 CDS ycaP NC_012759.1 858953 859645 D MG1655 equivalent: b0906; hypothetical protein 858953..859645 Escherichia coli BW2952 7952781 YP_002925961.1 CDS serC NC_012759.1 859844 860932 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 859844..860932 Escherichia coli BW2952 7952703 YP_002925962.1 CDS aroA NC_012759.1 861003 862286 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 861003..862286 Escherichia coli BW2952 7952326 YP_002925963.1 CDS ycaL NC_012759.1 862455 863219 D MG1655 equivalent: b0909; putative peptidase with chaperone function 862455..863219 Escherichia coli BW2952 7952370 YP_002925964.1 CDS cmk NC_012759.1 863392 864075 D Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 863392..864075 Escherichia coli BW2952 7955289 YP_002925965.1 CDS rpsA NC_012759.1 864186 865859 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 864186..865859 Escherichia coli BW2952 7953189 YP_002925966.1 CDS ihfB NC_012759.1 866019 866303 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 866019..866303 Escherichia coli BW2952 7952272 YP_002925967.1 CDS ycaI NC_012759.1 866511 868775 D MG1655 equivalent: b0913; hypothetical protein 866511..868775 Escherichia coli BW2952 7954011 YP_002925968.1 CDS msbA NC_012759.1 868812 870560 D involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease 868812..870560 Escherichia coli BW2952 7952704 YP_002925969.1 CDS lpxK NC_012759.1 870557 871543 D transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 870557..871543 Escherichia coli BW2952 7953693 YP_002925970.1 CDS ycaQ NC_012759.1 871580 872812 D MG1655 equivalent: b0916; hypothetical protein 871580..872812 Escherichia coli BW2952 7954144 YP_002925971.1 CDS ycaR NC_012759.1 872864 873046 D MG1655 equivalent: b0917; hypothetical protein 872864..873046 Escherichia coli BW2952 7952941 YP_002925972.1 CDS kdsB NC_012759.1 873043 873789 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 873043..873789 Escherichia coli BW2952 7952942 YP_002925973.1 CDS ycbJ NC_012759.1 873943 874836 D MG1655 equivalent: b0919; hypothetical protein 873943..874836 Escherichia coli BW2952 7952303 YP_002925974.1 CDS ycbC NC_012759.1 874813 875592 R MG1655 equivalent: b0920; hypothetical protein complement(874813..875592) Escherichia coli BW2952 7952943 YP_002925975.1 CDS smtA NC_012759.1 875728 876513 D involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; putative metallothionein SmtA 875728..876513 Escherichia coli BW2952 7952667 YP_002925976.1 CDS mukF NC_012759.1 876510 877832 D acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 876510..877832 Escherichia coli BW2952 7955578 YP_002925977.1 CDS mukE NC_012759.1 877840 878517 D acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 877840..878517 Escherichia coli BW2952 7954012 YP_002925978.1 CDS mukB NC_012759.1 878517 882977 D SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 878517..882977 Escherichia coli BW2952 7955793 YP_002925979.1 CDS ycbB NC_012759.1 883238 885085 D MG1655 equivalent: b0925; hypothetical protein 883238..885085 Escherichia coli BW2952 7953665 YP_002925980.1 CDS ycbK NC_012759.1 885266 885814 D MG1655 equivalent: b0926; hypothetical protein 885266..885814 Escherichia coli BW2952 7954676 YP_002925981.1 CDS ycbL NC_012759.1 885841 886488 D MG1655 equivalent: b0927; putative metal-binding enzyme 885841..886488 Escherichia coli BW2952 7952944 YP_002925982.1 CDS aspC NC_012759.1 886710 887900 R catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase complement(886710..887900) Escherichia coli BW2952 7955147 YP_002925983.1 CDS ompF NC_012759.1 888085 889173 R outer membrane porin F; 1a; Ia; b; outer membrane protein F complement(888085..889173) Escherichia coli BW2952 7952511 YP_002925984.1 CDS asnC NC_012759.1 889776 891176 R catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase complement(889776..891176) Escherichia coli BW2952 7954445 YP_002925985.1 CDS pncB NC_012759.1 891345 892547 R catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(891345..892547) Escherichia coli BW2952 7952509 YP_002925986.1 CDS pepN NC_012759.1 892813 895425 D MG1655 equivalent: b0932; aminopeptidase N 892813..895425 Escherichia coli BW2952 7954383 YP_002925987.1 CDS ssuB NC_012759.1 895468 896235 R part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit complement(895468..896235) Escherichia coli BW2952 7952473 YP_002925988.1 CDS ssuC NC_012759.1 896232 897023 R part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease subunit complement(896232..897023) Escherichia coli BW2952 7952447 YP_002925989.1 CDS ssuD NC_012759.1 897034 898179 R catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase complement(897034..898179) Escherichia coli BW2952 7952448 YP_002925990.1 CDS ssuA NC_012759.1 898176 899135 R part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit complement(898176..899135) Escherichia coli BW2952 7952446 YP_002925991.1 CDS ssuE NC_012759.1 899128 899703 R MG1655 equivalent: b0937; NAD(P)H-dependent FMN reductase complement(899128..899703) Escherichia coli BW2952 7952449 YP_002925992.1 CDS ycbQ NC_012759.1 900059 900598 D MG1655 equivalent: b0938; putative fimbrial-like adhesin protein 900059..900598 Escherichia coli BW2952 7954352 YP_002925993.1 CDS ycbR NC_012759.1 900681 901382 D MG1655 equivalent: b0939; putative periplasmic pilin chaperone 900681..901382 Escherichia coli BW2952 7954895 YP_002925994.1 CDS ycbS NC_012759.1 901407 904007 D MG1655 equivalent: b0940; putative outer membrane usher protein 901407..904007 Escherichia coli BW2952 7955302 YP_002925995.1 CDS ycbT NC_012759.1 903998 905068 D MG1655 equivalent: b0941; putative fimbrial-like adhesin protein 903998..905068 Escherichia coli BW2952 7955219 YP_002925996.1 CDS ycbU NC_012759.1 905080 905622 D MG1655 equivalent: b0942; putative fimbrial-like adhesin protein 905080..905622 Escherichia coli BW2952 7954896 YP_002925997.1 CDS ycbV NC_012759.1 905630 906145 D MG1655 equivalent: b0943; putative fimbrial-like adhesin protein 905630..906145 Escherichia coli BW2952 7954897 YP_002925998.1 CDS ycbF NC_012759.1 906138 906848 D MG1655 equivalent: b0944; putativi pili assembly chaperone 906138..906848 Escherichia coli BW2952 7954898 YP_002925999.1 CDS pyrD NC_012759.1 906959 907969 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 906959..907969 Escherichia coli BW2952 7955305 YP_002926000.1 CDS ycbW NC_012759.1 908143 908685 D MG1655 equivalent: b0946; hypothetical protein 908143..908685 Escherichia coli BW2952 7953255 YP_002926001.1 CDS ycbX NC_012759.1 908682 909791 R MG1655 equivalent: b0947; putative 2Fe-2S cluster-containing protein complement(908682..909791) Escherichia coli BW2952 7955450 YP_002926002.1 CDS rlmL NC_012759.1 910035 912143 D catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 910035..912143 Escherichia coli BW2952 7954584 YP_002926003.1 CDS uup NC_012759.1 912155 914062 D Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 912155..914062 Escherichia coli BW2952 7955157 YP_002926004.1 CDS pqiA NC_012759.1 914192 915445 D MG1655 equivalent: b0950; paraquat-inducible membrane protein A 914192..915445 Escherichia coli BW2952 7953733 YP_002926005.1 CDS pqiB NC_012759.1 915450 917090 D MG1655 equivalent: b0951; paraquat-inducible protein B 915450..917090 Escherichia coli BW2952 7954468 YP_002926006.1 CDS ymbA NC_012759.1 917087 917650 D MG1655 equivalent: b0952; hypothetical protein 917087..917650 Escherichia coli BW2952 7954469 YP_002926007.1 CDS rmf NC_012759.1 917906 918073 D MG1655 equivalent: b0953; ribosome modulation factor 917906..918073 Escherichia coli BW2952 7952945 YP_002926008.1 CDS fabA NC_012759.1 918143 918661 R catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase complement(918143..918661) Escherichia coli BW2952 7955977 YP_002926009.1 CDS ycbZ NC_012759.1 918730 920490 R MG1655 equivalent: b0955; putative peptidase complement(918730..920490) Escherichia coli BW2952 7952549 YP_002926010.1 CDS ycbG NC_012759.1 920676 921128 D MG1655 equivalent: b0956; hypothetical protein 920676..921128 Escherichia coli BW2952 7955270 YP_002926011.1 CDS ompA NC_012759.1 921204 922244 R OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A complement(921204..922244) Escherichia coli BW2952 7952946 YP_002926012.1 CDS sulA NC_012759.1 922601 923110 R MG1655 equivalent: b0958; SOS cell division inhibitor complement(922601..923110) Escherichia coli BW2952 7954448 YP_002926013.1 CDS sxy NC_012759.1 923329 923958 D MG1655 equivalent: b0959; hypothetical protein 923329..923958 Escherichia coli BW2952 7956059 YP_002926014.1 CDS yccS NC_012759.1 923921 926074 R MG1655 equivalent: b0960; putative inner membrane protein complement(923921..926074) Escherichia coli BW2952 7952947 YP_002926015.1 CDS yccF NC_012759.1 926093 926539 R MG1655 equivalent: b0961; hypothetical protein complement(926093..926539) Escherichia coli BW2952 7954988 YP_002926016.1 CDS helD NC_012759.1 926662 928716 D catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 926662..928716 Escherichia coli BW2952 7952668 YP_002926017.1 CDS mgsA NC_012759.1 928748 929206 R catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase complement(928748..929206) Escherichia coli BW2952 7953310 YP_002926018.1 CDS yccT NC_012759.1 929302 929964 R MG1655 equivalent: b0964; hypothetical protein complement(929302..929964) Escherichia coli BW2952 7954259 YP_002926019.1 CDS yccU NC_012759.1 930137 930550 D MG1655 equivalent: b0965; putative CoA-binding protein with NAD(P)-binding Rossmann-fold domain 930137..930550 Escherichia coli BW2952 7952782 YP_002926020.1 CDS hspQ NC_012759.1 930595 930912 R MG1655 equivalent: b0966; heat shock protein HspQ complement(930595..930912) Escherichia coli BW2952 7954696 YP_002926021.1 CDS yccW NC_012759.1 930970 932160 R MG1655 equivalent: b0967; putative methyltransferase complement(930970..932160) Escherichia coli BW2952 7953340 YP_002926022.1 CDS yccX NC_012759.1 932255 932533 D catalyzes the hydrolysis of acylphosphate; acylphosphatase 932255..932533 Escherichia coli BW2952 7955152 YP_002926023.1 CDS yccK NC_012759.1 932530 932859 R transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE complement(932530..932859) Escherichia coli BW2952 7954612 YP_002926024.1 CDS yccA NC_012759.1 932950 933609 R MG1655 equivalent: b0970; hypothetical protein complement(932950..933609) Escherichia coli BW2952 7955616 YP_002926025.1 CDS hyaA NC_012759.1 934330 935448 D MG1655 equivalent: b0972; hydrogenase 1, small subunit 934330..935448 Escherichia coli BW2952 7952049 YP_002926026.1 CDS hyaB NC_012759.1 935445 937238 D involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 935445..937238 Escherichia coli BW2952 7953937 YP_002926027.1 CDS hyaC NC_012759.1 937257 937964 D MG1655 equivalent: b0974; hydrogenase 1 b-type cytochrome subunit 937257..937964 Escherichia coli BW2952 7953936 YP_002926028.1 CDS hyaD NC_012759.1 937961 938548 D HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 937961..938548 Escherichia coli BW2952 7953935 YP_002926029.1 CDS hyaE NC_012759.1 938545 938943 D involved in processing hydrogenase proteins HyaA and HyaB; hydrogenase-1 operon protein HyaE 938545..938943 Escherichia coli BW2952 7955797 YP_002926030.1 CDS hyaF NC_012759.1 938940 939797 D MG1655 equivalent: b0977; protein involved in nickel incorporation into hydrogenase-1 proteins 938940..939797 Escherichia coli BW2952 7955798 YP_002926031.1 CDS appC NC_012759.1 939931 941475 D MG1655 equivalent: b0978; cytochrome bd-II oxidase, subunit I 939931..941475 Escherichia coli BW2952 7955795 YP_002926032.1 CDS appB NC_012759.1 941487 942623 D MG1655 equivalent: b0979; cytochrome bd-II oxidase, subunit II 941487..942623 Escherichia coli BW2952 7953191 YP_002926033.1 CDS yccB NC_012759.1 942636 942728 D expressed during stationary phase; membrane protein 942636..942728 Escherichia coli BW2952 7953192 YP_002926034.1 CDS appA NC_012759.1 942808 944106 D MG1655 equivalent: b0980; phosphoanhydride phosphorylase 942808..944106 Escherichia coli BW2952 7953976 YP_002926035.1 CDS etk NC_012759.1 944221 946401 R MG1655 equivalent: b0981; cryptic autophosphorylating protein tyrosine kinase Etk complement(944221..946401) Escherichia coli BW2952 7954527 YP_002926036.1 CDS etp NC_012759.1 946421 946867 R Etk and Etp are a tyrosine kinase-tyrosine phosphatase pair, etp dephosphorylates etk; phosphotyrosine-protein phosphatase complement(946421..946867) Escherichia coli BW2952 7953167 YP_002926037.1 CDS gfcE NC_012759.1 946855 947994 R MG1655 equivalent: b0983; putative exopolysaccharide export protein complement(946855..947994) Escherichia coli BW2952 7954556 YP_002926038.1 CDS gfcD NC_012759.1 948040 950136 R MG1655 equivalent: b0984; hypothetical protein complement(948040..950136) Escherichia coli BW2952 7954865 YP_002926039.1 CDS gfcC NC_012759.1 950136 950882 R MG1655 equivalent: b0985; hypothetical protein complement(950136..950882) Escherichia coli BW2952 7952783 YP_002926040.1 CDS gfcB NC_012759.1 950879 951523 R MG1655 equivalent: b0986; putative outer membrane lipoprotein complement(950879..951523) Escherichia coli BW2952 7952784 YP_002926041.1 CDS gfcA NC_012759.1 951630 951935 R MG1655 equivalent: b0987; hypothetical protein complement(951630..951935) Escherichia coli BW2952 7955198 YP_002926042.1 CDS insA NC_012759.1 952024 952299 D MG1655 equivalent: b4516; KpLE2 phage-like element; IS1 repressor protein InsA 952024..952299 Escherichia coli BW2952 7955345 YP_002926043.1 CDS insB NC_012759.1 952218 952721 D MG1655 equivalent: b0988; IS1 transposase InsAB' 952218..952721 Escherichia coli BW2952 7954070 YP_002926044.1 CDS cspH NC_012759.1 953154 953366 R MG1655 equivalent: b0989; stress protein, member of the CspA-family complement(953154..953366) Escherichia coli BW2952 7954021 YP_002926045.1 CDS cspG NC_012759.1 953652 953864 D MG1655 equivalent: b0990; cold shock protein CspG 953652..953864 Escherichia coli BW2952 7956069 YP_002926046.1 CDS ymcE NC_012759.1 954038 954268 D MG1655 equivalent: b0991; cold shock gene 954038..954268 Escherichia coli BW2952 7953443 YP_002926047.1 CDS gnsA NC_012759.1 954258 954431 D MG1655 equivalent: b4517; putative regulator of phosphatidylethanolamine synthesis 954258..954431 Escherichia coli BW2952 7952652 YP_002926048.1 CDS yccM NC_012759.1 954480 955553 R MG1655 equivalent: b0992; putative 4Fe-4S membrane protein complement(954480..955553) Escherichia coli BW2952 7955565 YP_002926049.1 CDS torS NC_012759.1 955625 958369 R Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS complement(955625..958369) Escherichia coli BW2952 7954596 YP_002926050.1 CDS torT NC_012759.1 958452 959480 D periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 958452..959480 Escherichia coli BW2952 7953930 YP_002926051.1 CDS torR NC_012759.1 959453 960145 R response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR complement(959453..960145) Escherichia coli BW2952 7954500 YP_002926052.1 CDS torC NC_012759.1 960275 961447 D MG1655 equivalent: b0996; trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit 960275..961447 Escherichia coli BW2952 7953362 YP_002926053.1 CDS torA NC_012759.1 961447 963993 D MG1655 equivalent: b0997; trimethylamine N-oxide (TMAO) reductase I, catalytic subunit 961447..963993 Escherichia coli BW2952 7956191 YP_002926054.1 CDS torD NC_012759.1 963990 964589 D TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 963990..964589 Escherichia coli BW2952 7956190 YP_002926055.1 CDS cbpM NC_012759.1 964741 965046 R with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM complement(964741..965046) Escherichia coli BW2952 7952629 YP_002926056.1 CDS cbpA NC_012759.1 965046 965966 R functions as a co-chaperone of DnaK; functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA complement(965046..965966) Escherichia coli BW2952 7954277 YP_002926057.1 CDS yccE NC_012759.1 966227 967483 D MG1655 equivalent: b1001; hypothetical protein 966227..967483 Escherichia coli BW2952 7953175 YP_002926058.1 CDS agp NC_012759.1 967776 969017 D MG1655 equivalent: b1002; glucose-1-phosphatase/inositol phosphatase 967776..969017 Escherichia coli BW2952 7955451 YP_002926059.1 CDS yccJ NC_012759.1 969055 969282 R MG1655 equivalent: b1003; hypothetical protein complement(969055..969282) Escherichia coli BW2952 7953804 YP_002926060.1 CDS wrbA NC_012759.1 969303 969899 R stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA complement(969303..969899) Escherichia coli BW2952 7955346 YP_002926061.1 CDS ymdF NC_012759.1 970272 970445 D MG1655 equivalent: b4518; hypothetical protein 970272..970445 Escherichia coli BW2952 7954350 YP_002926062.1 CDS rutG NC_012759.1 970702 972030 R MG1655 equivalent: b1006; putative transporter complement(970702..972030) Escherichia coli BW2952 7953073 YP_002926063.1 CDS rutF NC_012759.1 972051 972545 R MG1655 equivalent: b1007; putative oxidoreductase, flavin:NADH component complement(972051..972545) Escherichia coli BW2952 7955654 YP_002926064.1 CDS rutE NC_012759.1 972556 973146 R MG1655 equivalent: b1008; hypothetical protein complement(972556..973146) Escherichia coli BW2952 7955253 YP_002926065.1 CDS rutD NC_012759.1 973156 973956 R MG1655 equivalent: b1009; putative hydrolase complement(973156..973956) Escherichia coli BW2952 7955222 YP_002926066.1 CDS rutC NC_012759.1 973964 974350 R MG1655 equivalent: b1010; hypothetical protein complement(973964..974350) Escherichia coli BW2952 7954953 YP_002926067.1 CDS rutB NC_012759.1 974362 975054 R MG1655 equivalent: b1011; putative enzyme complement(974362..975054) Escherichia coli BW2952 7952785 YP_002926068.1 CDS rutA NC_012759.1 975054 976202 R MG1655 equivalent: b1012; putative monooxygenase complement(975054..976202) Escherichia coli BW2952 7954838 YP_002926069.1 CDS rutR NC_012759.1 976433 977071 D MG1655 equivalent: b1013; putative DNA-binding transcriptional regulator 976433..977071 Escherichia coli BW2952 7955165 YP_002926070.1 CDS putA NC_012759.1 977111 981073 R proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase complement(977111..981073) Escherichia coli BW2952 7954794 YP_002926071.1 CDS putP NC_012759.1 981496 983004 D MG1655 equivalent: b1015; proline:sodium symporter 981496..983004 Escherichia coli BW2952 7953676 YP_002926072.1 CDS efeO NC_012759.1 984434 985561 D MG1655 equivalent: b1018; hypothetical protein 984434..985561 Escherichia coli BW2952 7955770 YP_002926073.1 CDS efeB NC_012759.1 985567 986838 D MG1655 equivalent: b1019; hypothetical protein 985567..986838 Escherichia coli BW2952 7952948 YP_002926074.1 CDS phoH NC_012759.1 987183 988247 D MG1655 equivalent: b1020; hypothetical protein 987183..988247 Escherichia coli BW2952 7952949 YP_002926075.1 CDS pgaD NC_012759.1 988297 988710 R in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export; putative PGA biosynthesis protein complement(988297..988710) Escherichia coli BW2952 7953089 YP_002926076.1 CDS pgaC NC_012759.1 988712 990037 R predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase complement(988712..990037) Escherichia coli BW2952 7954989 YP_002926077.1 CDS pgaB NC_012759.1 990030 992048 R in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export; outer membrane N-deacetylase complement(990030..992048) Escherichia coli BW2952 7954932 YP_002926078.1 CDS pgaA NC_012759.1 992057 994480 R outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA complement(992057..994480) Escherichia coli BW2952 7954850 YP_002926079.1 CDS BWG_0877 NC_012759.1 994837 995340 D Insertion element IS1 1/5/6 protein insB 994837..995340 Escherichia coli BW2952 7955211 YP_002926080.1 CDS ycdT NC_012759.1 995843 997201 D MG1655 equivalent: b1025; putative diguanylate cyclase 995843..997201 Escherichia coli BW2952 7954003 YP_002926081.1 CDS insF NC_012759.1 997242 998108 R MG1655 equivalent: b1026; IS3 element protein InsF complement(997242..998108) Escherichia coli BW2952 7954728 YP_002926082.1 CDS insE NC_012759.1 998105 998413 R MG1655 equivalent: b1027; IS3 element protein InsE complement(998105..998413) Escherichia coli BW2952 7954033 YP_002926083.1 CDS ycdU NC_012759.1 998810 999796 D MG1655 equivalent: b1029; putative inner membrane protein 998810..999796 Escherichia coli BW2952 7954029 YP_002926084.1 CDS ghrA NC_012759.1 1001034 1001972 D MG1655 equivalent: b1033; 2-ketoacid reductase 1001034..1001972 Escherichia coli BW2952 7952050 YP_002926085.1 CDS ycdX NC_012759.1 1002027 1002764 D MG1655 equivalent: b1034; putative hydrolase 1002027..1002764 Escherichia coli BW2952 7952262 YP_002926086.1 CDS ycdY NC_012759.1 1002788 1003342 D MG1655 equivalent: b1035; hypothetical protein 1002788..1003342 Escherichia coli BW2952 7955754 YP_002926087.1 CDS ycdZ NC_012759.1 1003444 1003935 D MG1655 equivalent: b1036; putative inner membrane protein 1003444..1003935 Escherichia coli BW2952 7952950 YP_002926088.1 CDS csgG NC_012759.1 1003999 1004832 R MG1655 equivalent: b1037; outer membrane lipoprotein complement(1003999..1004832) Escherichia coli BW2952 7955033 YP_002926089.1 CDS csgF NC_012759.1 1004859 1005275 R nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF complement(1004859..1005275) Escherichia coli BW2952 7954437 YP_002926090.1 CDS csgE NC_012759.1 1005300 1005689 R chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE complement(1005300..1005689) Escherichia coli BW2952 7955645 YP_002926091.1 CDS csgD NC_012759.1 1005694 1006344 R activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD complement(1005694..1006344) Escherichia coli BW2952 7954581 YP_002926092.1 CDS csgB NC_012759.1 1007099 1007554 D CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1007099..1007554 Escherichia coli BW2952 7953386 YP_002926093.1 CDS csgA NC_012759.1 1007595 1008050 D MG1655 equivalent: b1042; cryptic curlin major subunit 1007595..1008050 Escherichia coli BW2952 7953174 YP_002926094.1 CDS csgC NC_012759.1 1008109 1008441 D involved in autoagglutination of curliated cells; not involved in production of curli fibers; putative autoagglutination protein 1008109..1008441 Escherichia coli BW2952 7953170 YP_002926095.1 CDS ymdA NC_012759.1 1008562 1008873 D MG1655 equivalent: b1044; hypothetical protein 1008562..1008873 Escherichia coli BW2952 7954704 YP_002926096.1 CDS ymdB NC_012759.1 1008968 1009501 D MG1655 equivalent: b1045; hypothetical protein 1008968..1009501 Escherichia coli BW2952 7955452 YP_002926097.1 CDS ymdC NC_012759.1 1009503 1010924 D MG1655 equivalent: b1046; putative hydrolase 1009503..1010924 Escherichia coli BW2952 7952951 YP_002926098.1 CDS mdoC NC_012759.1 1010932 1012089 R required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein complement(1010932..1012089) Escherichia coli BW2952 7954963 YP_002926099.1 CDS mdoG NC_012759.1 1012483 1014018 D involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1012483..1014018 Escherichia coli BW2952 7954232 YP_002926100.1 CDS mdoH NC_012759.1 1014011 1016554 D necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1014011..1016554 Escherichia coli BW2952 7953790 YP_002926101.1 CDS yceK NC_012759.1 1016727 1016954 D MG1655 equivalent: b1050; hypothetical protein 1016727..1016954 Escherichia coli BW2952 7953792 YP_002926102.1 CDS msyB NC_012759.1 1016955 1017329 R MG1655 equivalent: b1051; hypothetical protein complement(1016955..1017329) Escherichia coli BW2952 7955113 YP_002926103.1 CDS mdtG NC_012759.1 1017412 1018638 R Confers resistance to fosfomycin and deoxycholate; drug efflux system protein MdtG complement(1017412..1018638) Escherichia coli BW2952 7955347 YP_002926104.1 CDS lpxL NC_012759.1 1018810 1019730 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(1018810..1019730) Escherichia coli BW2952 7954827 YP_002926105.1 CDS yceA NC_012759.1 1019955 1021007 D MG1655 equivalent: b1055; hypothetical protein 1019955..1021007 Escherichia coli BW2952 7954122 YP_002926106.1 CDS yceI NC_012759.1 1021049 1021624 R MG1655 equivalent: b1056; hypothetical protein complement(1021049..1021624) Escherichia coli BW2952 7952952 YP_002926107.1 CDS yceJ NC_012759.1 1021628 1022194 R MG1655 equivalent: b1057; putative cytochrome b561 complement(1021628..1022194) Escherichia coli BW2952 7955348 YP_002926108.1 CDS yceO NC_012759.1 1022455 1022595 R MG1655 equivalent: b1058; hypothetical protein complement(1022455..1022595) Escherichia coli BW2952 7954708 YP_002926109.1 CDS solA NC_012759.1 1022616 1023734 R catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase complement(1022616..1023734) Escherichia coli BW2952 7955349 YP_002926110.1 CDS bssS NC_012759.1 1023849 1024103 R BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS complement(1023849..1024103) Escherichia coli BW2952 7954406 YP_002926111.1 CDS dinI NC_012759.1 1024390 1024635 R MG1655 equivalent: b1061; DNA damage-inducible protein I complement(1024390..1024635) Escherichia coli BW2952 7955350 YP_002926112.1 CDS pyrC NC_012759.1 1024709 1025755 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(1024709..1025755) Escherichia coli BW2952 7953303 YP_002926113.1 CDS yceB NC_012759.1 1025861 1026421 R MG1655 equivalent: b1063; hypothetical protein complement(1025861..1026421) Escherichia coli BW2952 7953254 YP_002926114.1 CDS grxB NC_012759.1 1026555 1027202 R cofactor involved in the reduction of disulfides; glutaredoxin complement(1026555..1027202) Escherichia coli BW2952 7955106 YP_002926115.1 CDS mdtH NC_012759.1 1027266 1028474 R Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH complement(1027266..1028474) Escherichia coli BW2952 7953836 YP_002926116.1 CDS rimJ NC_012759.1 1028710 1029294 D MG1655 equivalent: b1066; ribosomal-protein-S5-alanine N-acetyltransferase 1028710..1029294 Escherichia coli BW2952 7954828 YP_002926117.1 CDS yceH NC_012759.1 1029305 1029952 D MG1655 equivalent: b1067; hypothetical protein 1029305..1029952 Escherichia coli BW2952 7955976 YP_002926118.1 CDS yceM NC_012759.1 1029954 1030877 D MG1655 equivalent: b1068; putative oxidoreductase with NAD(P)-binding Rossmann-fold domain 1029954..1030877 Escherichia coli BW2952 7952953 YP_002926119.1 CDS yceN NC_012759.1 1030987 1032522 D MG1655 equivalent: b1069; putative inner membrane protein 1030987..1032522 Escherichia coli BW2952 7955250 YP_002926120.1 CDS flgN NC_012759.1 1032562 1032978 R MG1655 equivalent: b1070; export chaperone for FlgK and FlgL complement(1032562..1032978) Escherichia coli BW2952 7955034 YP_002926121.1 CDS flgM NC_012759.1 1032983 1033276 R regulates the flagellar specific sigma28 transcription factor; anti-sigma-28 factor FlgM complement(1032983..1033276) Escherichia coli BW2952 7953550 YP_002926122.1 CDS flgA NC_012759.1 1033352 1034011 R required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA complement(1033352..1034011) Escherichia coli BW2952 7952484 YP_002926123.1 CDS flgB NC_012759.1 1034166 1034582 D with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB 1034166..1034582 Escherichia coli BW2952 7952518 YP_002926124.1 CDS flgC NC_012759.1 1034586 1034990 D with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1034586..1034990 Escherichia coli BW2952 7953590 YP_002926125.1 CDS flgD NC_012759.1 1035002 1035697 D acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1035002..1035697 Escherichia coli BW2952 7953591 YP_002926126.1 CDS flgE NC_012759.1 1035722 1036930 D the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1035722..1036930 Escherichia coli BW2952 7953596 YP_002926127.1 CDS flgF NC_012759.1 1036950 1037705 D FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1036950..1037705 Escherichia coli BW2952 7953597 YP_002926128.1 CDS flgG NC_012759.1 1037877 1038659 D makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1037877..1038659 Escherichia coli BW2952 7953592 YP_002926129.1 CDS flgH NC_012759.1 1038712 1039410 D part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1038712..1039410 Escherichia coli BW2952 7953589 YP_002926130.1 CDS flgI NC_012759.1 1039422 1040519 D part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 1039422..1040519 Escherichia coli BW2952 7953605 YP_002926131.1 CDS flgJ NC_012759.1 1040519 1041460 D Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1040519..1041460 Escherichia coli BW2952 7954903 YP_002926132.1 CDS flgK NC_012759.1 1041526 1043169 D with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1041526..1043169 Escherichia coli BW2952 7954319 YP_002926133.1 CDS flgL NC_012759.1 1043181 1044134 D with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1043181..1044134 Escherichia coli BW2952 7953599 YP_002926134.1 CDS rne NC_012759.1 1044330 1047515 R bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E complement(1044330..1047515) Escherichia coli BW2952 7953598 YP_002926135.1 CDS yceQ NC_012759.1 1047650 1047970 D MG1655 equivalent: b1085; hypothetical protein 1047650..1047970 Escherichia coli BW2952 7953739 YP_002926136.1 CDS rluC NC_012759.1 1048088 1049047 D catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1048088..1049047 Escherichia coli BW2952 7955453 YP_002926137.1 CDS yceF NC_012759.1 1049159 1049743 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(1049159..1049743) Escherichia coli BW2952 7952249 YP_002926138.1 CDS yceD NC_012759.1 1049942 1050463 D MG1655 equivalent: b1088; hypothetical protein 1049942..1050463 Escherichia coli BW2952 7952172 YP_002926139.1 CDS rpmF NC_012759.1 1050515 1050688 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1050515..1050688 Escherichia coli BW2952 7952954 YP_002926140.1 CDS plsX NC_012759.1 1050769 1051839 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 1050769..1051839 Escherichia coli BW2952 7952360 YP_002926141.1 CDS fabH NC_012759.1 1051907 1052860 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1051907..1052860 Escherichia coli BW2952 7953561 YP_002926142.1 CDS fabD NC_012759.1 1052876 1053805 D MG1655 equivalent: b1092; malonyl CoA-ACP transacylase 1052876..1053805 Escherichia coli BW2952 7952320 YP_002926143.1 CDS fabG NC_012759.1 1053818 1054552 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1053818..1054552 Escherichia coli BW2952 7954202 YP_002926144.1 CDS acpP NC_012759.1 1054763 1054999 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1054763..1054999 Escherichia coli BW2952 7952317 YP_002926145.1 CDS fabF NC_012759.1 1055087 1056328 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 1055087..1056328 Escherichia coli BW2952 7952413 YP_002926146.1 CDS pabC NC_012759.1 1056448 1057257 D catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1056448..1057257 Escherichia coli BW2952 7952319 YP_002926147.1 CDS yceG NC_012759.1 1057260 1058282 D MG1655 equivalent: b1097; hypothetical protein 1057260..1058282 Escherichia coli BW2952 7952328 YP_002926148.1 CDS tmk NC_012759.1 1058272 1058913 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1058272..1058913 Escherichia coli BW2952 7954645 YP_002926149.1 CDS holB NC_012759.1 1058910 1059914 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1058910..1059914 Escherichia coli BW2952 7956150 YP_002926150.1 CDS ycfH NC_012759.1 1059925 1060722 D MG1655 equivalent: b1100; putative metallodependent hydrolase 1059925..1060722 Escherichia coli BW2952 7953322 YP_002926151.1 CDS ptsG NC_012759.1 1061017 1062450 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunit IIBC 1061017..1062450 Escherichia coli BW2952 7955148 YP_002926152.1 CDS fhuE NC_012759.1 1062510 1064699 R MG1655 equivalent: b1102; ferric-rhodotorulic acid outer membrane transporter complement(1062510..1064699) Escherichia coli BW2952 7953682 YP_002926153.1 CDS hinT NC_012759.1 1065033 1065392 D MG1655 equivalent: b1103; purine nucleoside phosphoramidase 1065033..1065392 Escherichia coli BW2952 7953571 YP_002926154.1 CDS ycfL NC_012759.1 1065395 1065772 D MG1655 equivalent: b1104; hypothetical protein 1065395..1065772 Escherichia coli BW2952 7955822 YP_002926155.1 CDS ycfM NC_012759.1 1065786 1066427 D MG1655 equivalent: b1105; putative outer membrane lipoprotein 1065786..1066427 Escherichia coli BW2952 7955454 YP_002926156.1 CDS thiK NC_012759.1 1066408 1067232 D catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1066408..1067232 Escherichia coli BW2952 7955201 YP_002926157.1 CDS nagZ NC_012759.1 1067243 1068268 D hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1067243..1068268 Escherichia coli BW2952 7956126 YP_002926158.1 CDS ycfP NC_012759.1 1068291 1068833 D MG1655 equivalent: b1108; hypothetical protein 1068291..1068833 Escherichia coli BW2952 7952545 YP_002926159.1 CDS ndh NC_012759.1 1069233 1070537 D MG1655 equivalent: b1109; respiratory NADH dehydrogenase 2/cupric reductase 1069233..1070537 Escherichia coli BW2952 7952955 YP_002926160.1 CDS ycfJ NC_012759.1 1070747 1071286 D MG1655 equivalent: b1110; hypothetical protein 1070747..1071286 Escherichia coli BW2952 7955943 YP_002926161.1 CDS ycfQ NC_012759.1 1071348 1071980 R MG1655 equivalent: b1111; putative DNA-binding transcriptional regulator complement(1071348..1071980) Escherichia coli BW2952 7955455 YP_002926162.1 CDS bhsA NC_012759.1 1072221 1072478 D MG1655 equivalent: b1112; hypothetical protein 1072221..1072478 Escherichia coli BW2952 7954752 YP_002926163.1 CDS ycfS NC_012759.1 1072560 1073522 R MG1655 equivalent: b1113; hypothetical protein complement(1072560..1073522) Escherichia coli BW2952 7955456 YP_002926164.1 CDS mfd NC_012759.1 1073666 1077112 R MG1655 equivalent: b1114; transcription-repair coupling factor complement(1073666..1077112) Escherichia coli BW2952 7952786 YP_002926165.1 CDS ycfT NC_012759.1 1077240 1078313 R MG1655 equivalent: b1115; putative inner membrane protein complement(1077240..1078313) Escherichia coli BW2952 7956173 YP_002926166.1 CDS lolC NC_012759.1 1078575 1079774 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1078575..1079774 Escherichia coli BW2952 7954990 YP_002926167.1 CDS lolD NC_012759.1 1079767 1080468 D outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1079767..1080468 Escherichia coli BW2952 7954452 YP_002926168.1 CDS lolE NC_012759.1 1080468 1081712 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1080468..1081712 Escherichia coli BW2952 7954453 YP_002926169.1 CDS nagK NC_012759.1 1081741 1082652 D catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1081741..1082652 Escherichia coli BW2952 7954454 YP_002926170.1 CDS cobB NC_012759.1 1082668 1083507 D Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1082668..1083507 Escherichia coli BW2952 7954335 YP_002926171.1 CDS ycfZ NC_012759.1 1083627 1084415 R MG1655 equivalent: b1121; putative inner membrane protein complement(1083627..1084415) Escherichia coli BW2952 7953230 YP_002926172.1 CDS ymfA NC_012759.1 1084412 1084873 R MG1655 equivalent: b1122; putative inner membrane protein complement(1084412..1084873) Escherichia coli BW2952 7954991 YP_002926173.1 CDS potD NC_012759.1 1084931 1085977 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter substrate-binding protein complement(1084931..1085977) Escherichia coli BW2952 7954992 YP_002926174.1 CDS potC NC_012759.1 1085974 1086768 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1085974..1086768) Escherichia coli BW2952 7954563 YP_002926175.1 CDS potB NC_012759.1 1086765 1087592 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1086765..1087592) Escherichia coli BW2952 7954564 YP_002926176.1 CDS potA NC_012759.1 1087606 1088742 R functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase complement(1087606..1088742) Escherichia coli BW2952 7954565 YP_002926177.1 CDS pepT NC_012759.1 1088992 1090218 D catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1088992..1090218 Escherichia coli BW2952 7954566 YP_002926178.1 CDS ycfD NC_012759.1 1090267 1091388 R MG1655 equivalent: b1128; hypothetical protein complement(1090267..1091388) Escherichia coli BW2952 7954473 YP_002926179.1 CDS phoQ NC_012759.1 1091464 1092924 R MG1655 equivalent: b1129; sensor protein PhoQ complement(1091464..1092924) Escherichia coli BW2952 7952787 YP_002926180.1 CDS phoP NC_012759.1 1092924 1093595 R response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP complement(1092924..1093595) Escherichia coli BW2952 7956010 YP_002926181.1 CDS purB NC_012759.1 1093764 1095134 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(1093764..1095134) Escherichia coli BW2952 7953357 YP_002926182.1 CDS hflD NC_012759.1 1095138 1095779 R HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein complement(1095138..1095779) Escherichia coli BW2952 7952424 YP_002926183.1 CDS mnmA NC_012759.1 1095815 1096921 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(1095815..1096921) Escherichia coli BW2952 7955129 YP_002926184.1 CDS nudJ NC_012759.1 1096975 1097436 R MG1655 equivalent: b1134; bifunctional thiamin pyrimidine pyrophosphate hydrolase/ thiamin pyrophosphate hydrolase complement(1096975..1097436) Escherichia coli BW2952 7956195 YP_002926185.1 CDS rluE NC_012759.1 1097446 1098099 R catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E complement(1097446..1098099) Escherichia coli BW2952 7952574 YP_002926186.1 CDS icd NC_012759.1 1098271 1099521 D Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1098271..1099521 Escherichia coli BW2952 7952246 YP_002926187.1 CDS elbA NC_012759.1 1099624 1099947 R MG1655 equivalent: b1160; hypothetical protein complement(1099624..1099947) Escherichia coli BW2952 7953511 YP_002926188.1 CDS ycgX NC_012759.1 1100647 1101051 R MG1655 equivalent: b1161; hypothetical protein complement(1100647..1101051) Escherichia coli BW2952 7955352 YP_002926189.1 CDS ycgE NC_012759.1 1101272 1102003 R MG1655 equivalent: b1162; putative DNA-binding transcriptional regulator complement(1101272..1102003) Escherichia coli BW2952 7955353 YP_002926190.1 CDS ycgF NC_012759.1 1102208 1103419 R MG1655 equivalent: b1163; putative FAD-binding phosphodiesterase complement(1102208..1103419) Escherichia coli BW2952 7954753 YP_002926191.1 CDS ycgZ NC_012759.1 1103733 1103969 D MG1655 equivalent: b1164; hypothetical protein 1103733..1103969 Escherichia coli BW2952 7954867 YP_002926192.1 CDS ymgA NC_012759.1 1104012 1104284 D MG1655 equivalent: b1165; hypothetical protein 1104012..1104284 Escherichia coli BW2952 7955457 YP_002926193.1 CDS ariR NC_012759.1 1104313 1104579 D MG1655 equivalent: b1166; hypothetical protein 1104313..1104579 Escherichia coli BW2952 7955458 YP_002926194.1 CDS ymgC NC_012759.1 1104692 1104940 D MG1655 equivalent: b1167; hypothetical protein 1104692..1104940 Escherichia coli BW2952 7955459 YP_002926195.1 CDS ycgG NC_012759.1 1105272 1106795 D MG1655 equivalent: b1168; hypothetical protein 1105272..1106795 Escherichia coli BW2952 7955460 YP_002926196.1 CDS ymgF NC_012759.1 1106927 1107145 D MG1655 equivalent: b4520; hypothetical protein 1106927..1107145 Escherichia coli BW2952 7952705 YP_002926197.1 CDS ymgD NC_012759.1 1110249 1110578 R MG1655 equivalent: b1171; hypothetical protein complement(1110249..1110578) Escherichia coli BW2952 7955527 YP_002926198.1 CDS ymgG NC_012759.1 1110588 1110872 R MG1655 equivalent: b1172; hypothetical protein complement(1110588..1110872) Escherichia coli BW2952 7955354 YP_002926199.1 CDS ymgI NC_012759.1 1110934 1111107 R MG1655 equivalent: b4593; hypothetical protein complement(1110934..1111107) Escherichia coli BW2952 7955355 YP_002926200.1 CDS ymgJ NC_012759.1 1111208 1111393 D MG1655 equivalent: b4594; hypothetical protein 1111208..1111393 Escherichia coli BW2952 7953964 YP_002926201.1 CDS minE NC_012759.1 1112223 1112489 R works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE complement(1112223..1112489) Escherichia coli BW2952 7953977 YP_002926202.1 CDS minD NC_012759.1 1112493 1113305 R ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD complement(1112493..1113305) Escherichia coli BW2952 7952618 YP_002926203.1 CDS minC NC_012759.1 1113329 1114024 R blocks the formation of polar Z-ring septums; septum formation inhibitor complement(1113329..1114024) Escherichia coli BW2952 7954224 YP_002926204.1 CDS ycgJ NC_012759.1 1114544 1114912 D MG1655 equivalent: b1177; hypothetical protein 1114544..1114912 Escherichia coli BW2952 7952614 YP_002926205.1 CDS ycgK NC_012759.1 1115015 1115416 R MG1655 equivalent: b1178; hypothetical protein complement(1115015..1115416) Escherichia coli BW2952 7955461 YP_002926206.1 CDS ycgL NC_012759.1 1115625 1115951 D MG1655 equivalent: b1179; hypothetical protein 1115625..1115951 Escherichia coli BW2952 7955356 YP_002926207.1 CDS ycgM NC_012759.1 1116023 1116682 D MG1655 equivalent: b1180; hypothetical protein 1116023..1116682 Escherichia coli BW2952 7952956 YP_002926208.1 CDS ycgN NC_012759.1 1116759 1117220 D MG1655 equivalent: b1181; hypothetical protein 1116759..1117220 Escherichia coli BW2952 7955091 YP_002926209.1 CDS hlyE NC_012759.1 1117427 1118338 R Acts by forming a pore-like structure upon contact with mammalian cells; hemolysin E complement(1117427..1118338) Escherichia coli BW2952 7952957 YP_002926210.1 CDS umuD NC_012759.1 1118711 1119130 D binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1118711..1119130 Escherichia coli BW2952 7953904 YP_002926211.1 CDS umuC NC_012759.1 1119130 1120398 D binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1119130..1120398 Escherichia coli BW2952 7953329 YP_002926212.1 CDS dsbB NC_012759.1 1120444 1120974 R disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B complement(1120444..1120974) Escherichia coli BW2952 7953328 YP_002926213.1 CDS nhaB NC_012759.1 1121120 1122661 R involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter complement(1121120..1122661) Escherichia coli BW2952 7954458 YP_002926214.1 CDS fadR NC_012759.1 1122882 1123601 D Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1122882..1123601 Escherichia coli BW2952 7956055 YP_002926215.1 CDS ycgB NC_012759.1 1123653 1125185 R MG1655 equivalent: b1188; SpoVR family protein complement(1123653..1125185) Escherichia coli BW2952 7953425 YP_002926216.1 CDS dadA NC_012759.1 1125515 1126813 D catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1125515..1126813 Escherichia coli BW2952 7952788 YP_002926217.1 CDS dadX NC_012759.1 1126823 1127893 D catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1126823..1127893 Escherichia coli BW2952 7953226 YP_002926218.1 CDS cvrA NC_012759.1 1128279 1130015 R the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter complement(1128279..1130015) Escherichia coli BW2952 7952439 YP_002926219.1 CDS ldcA NC_012759.1 1130110 1131024 R catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A complement(1130110..1131024) Escherichia coli BW2952 7954683 YP_002926220.1 CDS emtA NC_012759.1 1131124 1131735 D MG1655 equivalent: b1193; lytic murein endotransglycosylase E 1131124..1131735 Escherichia coli BW2952 7954105 YP_002926221.1 CDS ycgR NC_012759.1 1131737 1132471 R MG1655 equivalent: b1194; protein involved in flagellar function complement(1131737..1132471) Escherichia coli BW2952 7954188 YP_002926222.1 CDS ymgE NC_012759.1 1132672 1132926 D MG1655 equivalent: b1195; putative inner membrane protein 1132672..1132926 Escherichia coli BW2952 7955794 YP_002926223.1 CDS ycgY NC_012759.1 1133104 1133544 D MG1655 equivalent: b1196; hypothetical protein 1133104..1133544 Escherichia coli BW2952 7955035 YP_002926224.1 CDS treA NC_012759.1 1133623 1135320 R periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase complement(1133623..1135320) Escherichia coli BW2952 7955462 YP_002926225.1 CDS dhaM NC_012759.1 1135640 1137061 R phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL; dihydroxyacetone kinase subunit DhaM complement(1135640..1137061) Escherichia coli BW2952 7954502 YP_002926226.1 CDS dhaL NC_012759.1 1137069 1137701 R with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL complement(1137069..1137701) Escherichia coli BW2952 7953710 YP_002926227.1 CDS dhaK NC_012759.1 1137712 1138782 R with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK complement(1137712..1138782) Escherichia coli BW2952 7953257 YP_002926228.1 CDS dhaR NC_012759.1 1139010 1140929 D Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 1139010..1140929 Escherichia coli BW2952 7953258 YP_002926229.1 CDS ycgV NC_012759.1 1141029 1143896 R MG1655 equivalent: b1202; putative adhesin complement(1141029..1143896) Escherichia coli BW2952 7954822 YP_002926230.1 CDS ychF NC_012759.1 1144665 1145756 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(1144665..1145756) Escherichia coli BW2952 7954624 YP_002926231.1 CDS pth NC_012759.1 1145873 1146457 R Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase complement(1145873..1146457) Escherichia coli BW2952 7954941 YP_002926232.1 CDS ychH NC_012759.1 1146735 1147013 D YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1146735..1147013 Escherichia coli BW2952 7954485 YP_002926233.1 CDS ychM NC_012759.1 1147068 1148747 R putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; putative sulfate transporter YchM complement(1147068..1148747) Escherichia coli BW2952 7955036 YP_002926234.1 CDS prs NC_012759.1 1148872 1149819 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(1148872..1149819) Escherichia coli BW2952 7955655 YP_002926235.1 CDS ipk NC_012759.1 1149970 1150821 R An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(1149970..1150821) Escherichia coli BW2952 7954554 YP_002926236.1 CDS lolB NC_012759.1 1150821 1151444 R Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB complement(1150821..1151444) Escherichia coli BW2952 7952332 YP_002926237.1 CDS hemA NC_012759.1 1151658 1152914 D catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1151658..1152914 Escherichia coli BW2952 7952625 YP_002926238.1 CDS prfA NC_012759.1 1152956 1154038 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1152956..1154038 Escherichia coli BW2952 7953831 YP_002926239.1 CDS prmC NC_012759.1 1154038 1154871 D HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1154038..1154871 Escherichia coli BW2952 7954474 YP_002926240.1 CDS ychQ NC_012759.1 1154868 1155260 D MG1655 equivalent: b1213; putative transcriptional regulator 1154868..1155260 Escherichia coli BW2952 7954333 YP_002926241.1 CDS ychA NC_012759.1 1155264 1156073 D MG1655 equivalent: b1214; putative transcriptional regulator 1155264..1156073 Escherichia coli BW2952 7955633 YP_002926242.1 CDS kdsA NC_012759.1 1156109 1156963 D catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1156109..1156963 Escherichia coli BW2952 7955634 YP_002926243.1 CDS ldrA NC_012759.1 1157112 1157219 R MG1655 equivalent: b4419; toxic polypeptide, small complement(1157112..1157219) Escherichia coli BW2952 7952301 YP_002926244.1 CDS ldrB NC_012759.1 1157647 1157754 R MG1655 equivalent: b4421; toxic polypeptide, small complement(1157647..1157754) Escherichia coli BW2952 7952173 YP_002926245.1 CDS ldrC NC_012759.1 1158182 1158289 R MG1655 equivalent: b4423; toxic polypeptide, small complement(1158182..1158289) Escherichia coli BW2952 7952174 YP_002926246.1 CDS chaA NC_012759.1 1158693 1159793 R MG1655 equivalent: b1216; calcium/sodium:proton antiporter complement(1158693..1159793) Escherichia coli BW2952 7952175 YP_002926247.1 CDS chaB NC_012759.1 1160063 1160293 D in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 1160063..1160293 Escherichia coli BW2952 7952589 YP_002926248.1 CDS chaC NC_012759.1 1160451 1161146 D MG1655 equivalent: b1218; regulatory protein for cation transport 1160451..1161146 Escherichia coli BW2952 7954682 YP_002926249.1 CDS ychN NC_012759.1 1161190 1161543 R MG1655 equivalent: b1219; hypothetical protein complement(1161190..1161543) Escherichia coli BW2952 7955930 YP_002926250.1 CDS ychO NC_012759.1 1161728 1163122 D MG1655 equivalent: b1220; hypothetical protein 1161728..1163122 Escherichia coli BW2952 7952789 YP_002926251.1 CDS narL NC_012759.1 1163123 1163773 R two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL complement(1163123..1163773) Escherichia coli BW2952 7955085 YP_002926252.1 CDS narX NC_012759.1 1163766 1165562 R MG1655 equivalent: b1222; nitrate/nitrite sensor protein NarX complement(1163766..1165562) Escherichia coli BW2952 7953356 YP_002926253.1 CDS narK NC_012759.1 1165901 1167292 D MG1655 equivalent: b1223; nitrate/nitrite transporter 1165901..1167292 Escherichia coli BW2952 7956020 YP_002926254.1 CDS narG NC_012759.1 1167808 1171551 D MG1655 equivalent: b1224; nitrate reductase 1 subunit alpha 1167808..1171551 Escherichia coli BW2952 7954398 YP_002926255.1 CDS narH NC_012759.1 1171548 1173086 D MG1655 equivalent: b1225; nitrate reductase 1, beta (Fe-S) subunit 1171548..1173086 Escherichia coli BW2952 7954387 YP_002926256.1 CDS narJ NC_012759.1 1173083 1173793 D MG1655 equivalent: b1226; molybdenum-cofactor-assembly chaperone subunit (delta subunit) of nitrate reductase 1 1173083..1173793 Escherichia coli BW2952 7954388 YP_002926257.1 CDS narI NC_012759.1 1173793 1174470 D MG1655 equivalent: b1227; nitrate reductase 1, gamma (cytochrome b(NR)) subunit 1173793..1174470 Escherichia coli BW2952 7954286 YP_002926258.1 CDS ychS NC_012759.1 1174653 1174928 D MG1655 equivalent: b1228; hypothetical protein 1174653..1174928 Escherichia coli BW2952 7954389 YP_002926259.1 CDS tpr NC_012759.1 1175031 1175120 R MG1655 equivalent: b1229; putative protamine-like protein complement(1175031..1175120) Escherichia coli BW2952 7952080 YP_002926260.1 CDS purU NC_012759.1 1175726 1176568 R produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase complement(1175726..1176568) Escherichia coli BW2952 7952052 YP_002926261.1 CDS ychJ NC_012759.1 1176618 1177076 R MG1655 equivalent: b1233; hypothetical protein complement(1176618..1177076) Escherichia coli BW2952 7953630 YP_002926262.1 CDS rssA NC_012759.1 1177150 1178094 D MG1655 equivalent: b1234; hypothetical protein 1177150..1178094 Escherichia coli BW2952 7952790 YP_002926263.1 CDS BWG_1061 NC_012759.1 1178223 1178726 R Insertion element IS1 1/5/6 protein insB complement(1178223..1178726) Escherichia coli BW2952 7952958 YP_002926264.1 CDS rssB NC_012759.1 1179050 1179976 D MG1655 equivalent: b1235; response regulator of RpoS 1179050..1179976 Escherichia coli BW2952 7954002 YP_002926265.1 CDS galU NC_012759.1 1180178 1181086 D together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalU 1180178..1181086 Escherichia coli BW2952 7955945 YP_002926266.1 CDS hns NC_012759.1 1181230 1181643 R MG1655 equivalent: b1237; global DNA-binding transcriptional dual regulator H-NS complement(1181230..1181643) Escherichia coli BW2952 7953808 YP_002926267.1 CDS tdk NC_012759.1 1182248 1182865 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1182248..1182865 Escherichia coli BW2952 7953789 YP_002926268.1 CDS adhE NC_012759.1 1184167 1186842 R MG1655 equivalent: b1241; bifunctional acetaldehyde-CoA/alcohol dehydrogenase complement(1184167..1186842) Escherichia coli BW2952 7956148 YP_002926269.1 CDS ychE NC_012759.1 1187319 1187966 D MG1655 equivalent: b1242; hypothetical protein 1187319..1187966 Escherichia coli BW2952 7953653 YP_002926270.1 CDS oppA NC_012759.1 1188704 1190335 D MG1655 equivalent: b1243; oligopeptide transporter subunit 1188704..1190335 Escherichia coli BW2952 7955037 YP_002926271.1 CDS BWG_1070 NC_012759.1 1190894 1191076 D COG0428; Predicted divalent heavy-metal cations transporter 1190894..1191076 Escherichia coli BW2952 7954422 YP_002926272.1 CDS BWG_1071 NC_012759.1 1191063 1192013 D CvaB, IS186 transposase 1191063..1192013 Escherichia coli BW2952 7952648 YP_002926273.1 CDS oppC NC_012759.1 1192707 1193615 D MG1655 equivalent: b1245; oligopeptide transporter subunit 1192707..1193615 Escherichia coli BW2952 7952212 YP_002926274.1 CDS oppD NC_012759.1 1193627 1194640 D MG1655 equivalent: b1246; oligopeptide ABC transporter ATP-binding protein 1193627..1194640 Escherichia coli BW2952 7954424 YP_002926275.1 CDS oppF NC_012759.1 1194637 1195641 D MG1655 equivalent: b1247; oligopeptide transporter subunit 1194637..1195641 Escherichia coli BW2952 7954425 YP_002926276.1 CDS yciU NC_012759.1 1195694 1196023 R highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein complement(1195694..1196023) Escherichia coli BW2952 7954426 YP_002926277.1 CDS cls NC_012759.1 1196058 1197518 R catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase complement(1196058..1197518) Escherichia coli BW2952 7955357 YP_002926278.1 CDS yciY NC_012759.1 1197661 1197834 D MG1655 equivalent: b4595; hypothetical protein 1197661..1197834 Escherichia coli BW2952 7952608 YP_002926279.1 CDS kch NC_012759.1 1197889 1199142 R MG1655 equivalent: b1250; voltage-gated potassium channel complement(1197889..1199142) Escherichia coli BW2952 7953978 YP_002926280.1 CDS yciI NC_012759.1 1199442 1199738 R unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein complement(1199442..1199738) Escherichia coli BW2952 7956275 YP_002926281.1 CDS tonB NC_012759.1 1199962 1200681 D membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transporter 1199962..1200681 Escherichia coli BW2952 7954839 YP_002926282.1 CDS yciA NC_012759.1 1200721 1201119 R YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins; acyl-CoA thioester hydrolase complement(1200721..1201119) Escherichia coli BW2952 7954237 YP_002926283.1 CDS yciB NC_012759.1 1201224 1201763 R Involved in cell division; probably involved in intracellular septation; intracellular septation protein A complement(1201224..1201763) Escherichia coli BW2952 7954954 YP_002926284.1 CDS yciC NC_012759.1 1201793 1202536 R MG1655 equivalent: b1255; hypothetical protein complement(1201793..1202536) Escherichia coli BW2952 7954993 YP_002926285.1 CDS ompW NC_012759.1 1202893 1203531 D receptor for colicin S4; outer membrane protein W 1202893..1203531 Escherichia coli BW2952 7954994 YP_002926286.1 CDS yciE NC_012759.1 1203591 1204097 R MG1655 equivalent: b1257; hypothetical protein complement(1203591..1204097) Escherichia coli BW2952 7954450 YP_002926287.1 CDS yciF NC_012759.1 1204143 1204643 R MG1655 equivalent: b1258; hypothetical protein complement(1204143..1204643) Escherichia coli BW2952 7952791 YP_002926288.1 CDS yciG NC_012759.1 1204729 1204908 R MG1655 equivalent: b1259; hypothetical protein complement(1204729..1204908) Escherichia coli BW2952 7952792 YP_002926289.1 CDS trpA NC_012759.1 1205289 1206095 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1205289..1206095) Escherichia coli BW2952 7955358 YP_002926290.1 CDS trpB NC_012759.1 1206095 1207288 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1206095..1207288) Escherichia coli BW2952 7956211 YP_002926291.1 CDS trpC NC_012759.1 1207300 1208658 R monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(1207300..1208658) Escherichia coli BW2952 7956212 YP_002926292.1 CDS trpD NC_012759.1 1208662 1210257 R bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase complement(1208662..1210257) Escherichia coli BW2952 7953689 YP_002926293.1 CDS trpE NC_012759.1 1210257 1211819 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1210257..1211819) Escherichia coli BW2952 7953683 YP_002926295.1 CDS trpH NC_012759.1 1212093 1212974 D MG1655 equivalent: b1266; hypothetical protein 1212093..1212974 Escherichia coli BW2952 7956209 YP_002926296.1 CDS yciO NC_012759.1 1212971 1213591 D MG1655 equivalent: b1267; hypothetical protein 1212971..1213591 Escherichia coli BW2952 7952959 YP_002926297.1 CDS yciQ NC_012759.1 1213619 1215514 D MG1655 equivalent: b1268; putative inner membrane protein 1213619..1215514 Escherichia coli BW2952 7952960 YP_002926298.1 CDS rluB NC_012759.1 1215725 1216600 D catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1215725..1216600 Escherichia coli BW2952 7955038 YP_002926299.1 CDS btuR NC_012759.1 1216640 1217230 R catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase complement(1216640..1217230) Escherichia coli BW2952 7952250 YP_002926300.1 CDS yciK NC_012759.1 1217227 1217985 R MG1655 equivalent: b1271; short chain dehydrogenase complement(1217227..1217985) Escherichia coli BW2952 7952646 YP_002926301.1 CDS sohB NC_012759.1 1218205 1219254 D SohB; periplasmic protein; member of the peptidase S49 family; putative periplasmic protease 1218205..1219254 Escherichia coli BW2952 7955268 YP_002926302.1 CDS yciN NC_012759.1 1219290 1219541 R MG1655 equivalent: b1273; hypothetical protein complement(1219290..1219541) Escherichia coli BW2952 7954984 YP_002926303.1 CDS topA NC_012759.1 1219921 1222518 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1219921..1222518 Escherichia coli BW2952 7955359 YP_002926304.1 CDS cysB NC_012759.1 1222728 1223702 D LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1222728..1223702 Escherichia coli BW2952 7953333 YP_002926305.1 CDS ymiA NC_012759.1 1224033 1224161 D MG1655 equivalent: b4522; hypothetical protein 1224033..1224161 Escherichia coli BW2952 7953435 YP_002926306.1 CDS yciX NC_012759.1 1224164 1224331 D MG1655 equivalent: b4523; hypothetical protein 1224164..1224331 Escherichia coli BW2952 7953973 YP_002926307.1 CDS acnA NC_012759.1 1224704 1227379 D Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1224704..1227379 Escherichia coli BW2952 7953974 YP_002926308.1 CDS ribA NC_012759.1 1227443 1228033 R catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II complement(1227443..1228033) Escherichia coli BW2952 7952411 YP_002926309.1 CDS pgpB NC_012759.1 1228203 1228967 D MG1655 equivalent: b1278; phosphatidylglycerophosphatase B 1228203..1228967 Escherichia coli BW2952 7953875 YP_002926310.1 CDS yciS NC_012759.1 1229116 1229424 D MG1655 equivalent: b1279; hypothetical protein 1229116..1229424 Escherichia coli BW2952 7954523 YP_002926311.1 CDS yciM NC_012759.1 1229431 1230600 D MG1655 equivalent: b1280; hypothetical protein 1229431..1230600 Escherichia coli BW2952 7952706 YP_002926312.1 CDS pyrF NC_012759.1 1230794 1231531 D type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1230794..1231531 Escherichia coli BW2952 7952961 YP_002926313.1 CDS yciH NC_012759.1 1231531 1231857 D involved in start site selection during the initiation of translation; translation initiation factor Sui1 1231531..1231857 Escherichia coli BW2952 7954432 YP_002926314.1 CDS osmB NC_012759.1 1231983 1232201 R MG1655 equivalent: b1283; lipoprotein complement(1231983..1232201) Escherichia coli BW2952 7952962 YP_002926315.1 CDS yciT NC_012759.1 1232470 1233219 R MG1655 equivalent: b1284; putative DNA-binding transcriptional regulator complement(1232470..1233219) Escherichia coli BW2952 7954155 YP_002926316.1 CDS yciZ NC_012759.1 1233309 1233482 R MG1655 equivalent: b4596; hypothetical protein complement(1233309..1233482) Escherichia coli BW2952 7954754 YP_002926317.1 CDS gmr NC_012759.1 1233630 1235615 R c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator complement(1233630..1235615) Escherichia coli BW2952 7953965 YP_002926318.1 CDS rnb NC_012759.1 1235851 1237785 R Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II complement(1235851..1237785) Escherichia coli BW2952 7954280 YP_002926319.1 CDS yciW NC_012759.1 1237853 1238980 R MG1655 equivalent: b1287; putative oxidoreductase complement(1237853..1238980) Escherichia coli BW2952 7955962 YP_002926320.1 CDS fabI NC_012759.1 1239124 1239912 R Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase complement(1239124..1239912) Escherichia coli BW2952 7955223 YP_002926321.1 CDS ycjD NC_012759.1 1240280 1240633 R MG1655 equivalent: b1289; hypothetical protein complement(1240280..1240633) Escherichia coli BW2952 7953523 YP_002926322.1 CDS sapF NC_012759.1 1240701 1241507 R MG1655 equivalent: b1290; putative antimicrobial peptide transporter subunit complement(1240701..1241507) Escherichia coli BW2952 7952793 YP_002926323.1 CDS sapD NC_012759.1 1241509 1242501 R MG1655 equivalent: b1291; putative antimicrobial peptide transporter subunit complement(1241509..1242501) Escherichia coli BW2952 7954649 YP_002926324.1 CDS sapC NC_012759.1 1242501 1243391 R MG1655 equivalent: b1292; putative antimicrobial peptide transporter subunit complement(1242501..1243391) Escherichia coli BW2952 7954650 YP_002926325.1 CDS sapB NC_012759.1 1243378 1244343 R MG1655 equivalent: b1293; putative antimicrobial peptide transporter subunit complement(1243378..1244343) Escherichia coli BW2952 7954651 YP_002926326.1 CDS sapA NC_012759.1 1244340 1245983 R MG1655 equivalent: b1294; putative antimicrobial peptide transporter subunit complement(1244340..1245983) Escherichia coli BW2952 7954652 YP_002926327.1 CDS ymjA NC_012759.1 1246296 1246541 R MG1655 equivalent: b1295; hypothetical protein complement(1246296..1246541) Escherichia coli BW2952 7954653 YP_002926328.1 CDS puuP NC_012759.1 1246675 1248060 R MG1655 equivalent: b1296; putrescine importer complement(1246675..1248060) Escherichia coli BW2952 7955360 YP_002926329.1 CDS puuA NC_012759.1 1248363 1249781 R MG1655 equivalent: b1297; gamma-Glu-putrescine synthase complement(1248363..1249781) Escherichia coli BW2952 7955827 YP_002926330.1 CDS puuD NC_012759.1 1249993 1250757 D catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate; gamma-glutamyl-gamma-aminobutyrate hydrolase 1249993..1250757 Escherichia coli BW2952 7953767 YP_002926331.1 CDS puuR NC_012759.1 1250784 1251341 D regulates genes involved in putrescine degradation; DNA-binding transcriptional repressor PuuR 1250784..1251341 Escherichia coli BW2952 7953764 YP_002926332.1 CDS puuC NC_012759.1 1251616 1253103 D catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase 1251616..1253103 Escherichia coli BW2952 7953464 YP_002926333.1 CDS puuB NC_012759.1 1253105 1254385 D MG1655 equivalent: b1301; gamma-Glu-putrescine oxidase, FAD/NAD(P)-binding 1253105..1254385 Escherichia coli BW2952 7953765 YP_002926334.1 CDS puuE NC_012759.1 1254423 1255688 D putrescine-inducible GABA aminotransferase; catalyzes the formation of glutamate and succinate semialdehyde from 4-aminobutyrate and 2-oxoglutarate; 4-aminobutyrate transaminase 1254423..1255688 Escherichia coli BW2952 7953766 YP_002926335.1 CDS pspF NC_012759.1 1255808 1256785 R transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator complement(1255808..1256785) Escherichia coli BW2952 7953753 YP_002926336.1 CDS pspA NC_012759.1 1256952 1257620 D involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1256952..1257620 Escherichia coli BW2952 7953364 YP_002926337.1 CDS pspB NC_012759.1 1257674 1257898 D acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1257674..1257898 Escherichia coli BW2952 7955933 YP_002926338.1 CDS pspC NC_012759.1 1257898 1258257 D with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1257898..1258257 Escherichia coli BW2952 7953446 YP_002926339.1 CDS pspD NC_012759.1 1258266 1258487 D MG1655 equivalent: b1307; peripheral inner membrane phage-shock protein 1258266..1258487 Escherichia coli BW2952 7953379 YP_002926340.1 CDS pspE NC_012759.1 1258562 1258876 D rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1258562..1258876 Escherichia coli BW2952 7954486 YP_002926341.1 CDS ycjM NC_012759.1 1259089 1260768 D MG1655 equivalent: b1309; putative glucosyltransferase 1259089..1260768 Escherichia coli BW2952 7956139 YP_002926342.1 CDS ycjN NC_012759.1 1260782 1262074 D MG1655 equivalent: b1310; putative sugar transporter subunit: periplasmic-binding component of ABC superfamily 1260782..1262074 Escherichia coli BW2952 7954921 YP_002926343.1 CDS ycjO NC_012759.1 1262095 1262976 D MG1655 equivalent: b1311; putative sugar transporter subunit: membrane component of ABC superfamily 1262095..1262976 Escherichia coli BW2952 7955610 YP_002926344.1 CDS ycjP NC_012759.1 1262963 1263805 D MG1655 equivalent: b1312; putative sugar transporter subunit: membrane component of ABC superfamily 1262963..1263805 Escherichia coli BW2952 7955607 YP_002926345.1 CDS ycjQ NC_012759.1 1263836 1264888 D MG1655 equivalent: b1313; putative oxidoreductase, Zn-dependent and NAD(P)-binding 1263836..1264888 Escherichia coli BW2952 7955613 YP_002926346.1 CDS ycjR NC_012759.1 1264907 1265695 D MG1655 equivalent: b1314; putative enzyme 1264907..1265695 Escherichia coli BW2952 7955263 YP_002926347.1 CDS ycjS NC_012759.1 1265705 1266760 D MG1655 equivalent: b1315; putative oxidoreductase, NADH-binding 1265705..1266760 Escherichia coli BW2952 7954843 YP_002926348.1 CDS ycjT NC_012759.1 1266757 1269024 D MG1655 equivalent: b1316; putative hydrolase 1266757..1269024 Escherichia coli BW2952 7955256 YP_002926349.1 CDS ycjU NC_012759.1 1269021 1269680 D MG1655 equivalent: b1317; putative beta-phosphoglucomutase 1269021..1269680 Escherichia coli BW2952 7954964 YP_002926350.1 CDS ompG NC_012759.1 1270820 1271725 D MG1655 equivalent: b1319; outer membrane porin 1270820..1271725 Escherichia coli BW2952 7954669 YP_002926351.1 CDS ycjW NC_012759.1 1271836 1272834 R MG1655 equivalent: b1320; putative DNA-binding transcriptional regulator complement(1271836..1272834) Escherichia coli BW2952 7954444 YP_002926352.1 CDS ycjX NC_012759.1 1272990 1274387 D MG1655 equivalent: b1321; hypothetical protein 1272990..1274387 Escherichia coli BW2952 7954755 YP_002926353.1 CDS ycjF NC_012759.1 1274384 1275445 D MG1655 equivalent: b1322; hypothetical protein 1274384..1275445 Escherichia coli BW2952 7953090 YP_002926354.1 CDS tyrR NC_012759.1 1275593 1277134 D regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1275593..1277134 Escherichia coli BW2952 7952707 YP_002926355.1 CDS tpx NC_012759.1 1277178 1277684 R antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase complement(1277178..1277684) Escherichia coli BW2952 7953437 YP_002926356.1 CDS ycjG NC_012759.1 1277803 1278768 D MG1655 equivalent: b1325; L-Ala-D/L-Glu epimerase 1277803..1278768 Escherichia coli BW2952 7954145 YP_002926357.1 CDS mpaA NC_012759.1 1278743 1279531 R MG1655 equivalent: b1326; murein peptide amidase A complement(1278743..1279531) Escherichia coli BW2952 7954108 YP_002926358.1 CDS ycjY NC_012759.1 1279806 1280738 R MG1655 equivalent: b1327; putative hydrolase complement(1279806..1280738) Escherichia coli BW2952 7954322 YP_002926359.1 CDS ycjZ NC_012759.1 1280864 1281763 D MG1655 equivalent: b1328; putative DNA-binding transcriptional regulator 1280864..1281763 Escherichia coli BW2952 7954955 YP_002926360.1 CDS mppA NC_012759.1 1282100 1283713 D MG1655 equivalent: b1329; murein tripeptide (L-ala-gamma-D-glutamyl-meso-DAP) transporter subunit 1282100..1283713 Escherichia coli BW2952 7954795 YP_002926361.1 CDS ynaI NC_012759.1 1283764 1284795 R MG1655 equivalent: b1330; hypothetical protein complement(1283764..1284795) Escherichia coli BW2952 7954323 YP_002926362.1 CDS insH NC_012759.1 1284949 1285965 D MG1655 equivalent: b1331; IS5 transposase and trans-activator 1284949..1285965 Escherichia coli BW2952 7952669 YP_002926363.1 CDS ynaJ NC_012759.1 1286238 1286495 D MG1655 equivalent: b1332; putative inner membrane protein 1286238..1286495 Escherichia coli BW2952 7954045 YP_002926364.1 CDS uspE NC_012759.1 1286545 1287495 R with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE complement(1286545..1287495) Escherichia coli BW2952 7955039 YP_002926365.1 CDS fnr NC_012759.1 1287647 1288399 R Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator complement(1287647..1288399) Escherichia coli BW2952 7956072 YP_002926366.1 CDS ogt NC_012759.1 1289804 1290319 R MG1655 equivalent: b1335; O-6-alkylguanine-DNA:cysteine-protein methyltransferase complement(1289804..1290319) Escherichia coli BW2952 7956180 YP_002926367.1 CDS abgT NC_012759.1 1290330 1291856 R MG1655 equivalent: b1336; putative aminobenzoyl-glutamate transporter complement(1290330..1291856) Escherichia coli BW2952 7954416 YP_002926368.1 CDS abgB NC_012759.1 1291893 1293338 R MG1655 equivalent: b1337; putative peptidase, aminobenzoyl-glutamate utilization protein complement(1291893..1293338) Escherichia coli BW2952 7954702 YP_002926369.1 CDS abgA NC_012759.1 1293338 1294648 R MG1655 equivalent: b1338; putative peptidase, aminobenzoyl-glutamate utilization protein complement(1293338..1294648) Escherichia coli BW2952 7955290 YP_002926370.1 CDS abgR NC_012759.1 1294824 1295732 D MG1655 equivalent: b1339; putative DNA-binding transcriptional regulator 1294824..1295732 Escherichia coli BW2952 7955291 YP_002926371.1 CDS ydaL NC_012759.1 1296062 1296625 D MG1655 equivalent: b1340; hypothetical protein 1296062..1296625 Escherichia coli BW2952 7952081 YP_002926372.1 CDS ydaM NC_012759.1 1296646 1297878 R MG1655 equivalent: b1341; diguanylate cyclase complement(1296646..1297878) Escherichia coli BW2952 7952963 YP_002926373.1 CDS zntB NC_012759.1 1298133 1299116 D MG1655 equivalent: b1342; zinc transporter 1298133..1299116 Escherichia coli BW2952 7954733 YP_002926374.1 CDS dbpA NC_012759.1 1299594 1300967 D exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1299594..1300967 Escherichia coli BW2952 7955756 YP_002926375.1 CDS ttcA NC_012759.1 1301096 1302031 R TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase complement(1301096..1302031) Escherichia coli BW2952 7952537 YP_002926376.1 CDS intR NC_012759.1 1302083 1303318 R MG1655 equivalent: b1345; Rac prophage; integrase complement(1302083..1303318) Escherichia coli BW2952 7954672 YP_002926377.1 CDS ydaQ NC_012759.1 1303320 1303535 R MG1655 equivalent: b1346; Rac prophage protein complement(1303320..1303535) Escherichia coli BW2952 7955896 YP_002926378.1 CDS ydaC NC_012759.1 1303614 1303823 R Rac prophage; hypothetical protein complement(1303614..1303823) Escherichia coli BW2952 7955890 YP_002926379.1 CDS lar NC_012759.1 1303816 1304010 R seems to be involved in restriction alleviation and enhancement of modification by EcoKI, but not in restriction alleviation of type III restriction systems; Rac prophage; restriction alleviation and modification protein complement(1303816..1304010) Escherichia coli BW2952 7955904 YP_002926380.1 CDS recT NC_012759.1 1304067 1304876 R MG1655 equivalent: b1349; recombination and repair protein RecT complement(1304067..1304876) Escherichia coli BW2952 7955913 YP_002926381.1 CDS recE NC_012759.1 1304869 1307469 R The RecE (also known as exonuclease VIII) pathway is an alternative pathway for the initiation of homologous recombination in Escherichia coli. The RecE pathway is activated in recB, recC sbcA (suppressors of recB and recC) mutants. Activation of the RecE pathway results in the production of at least two phage proteins relevant for recombinational repair. RecE is a duplex DNA-specific exonuclease which produces 3' overhangs in duplex DNA by preferentially degrading the 5'-ending strands. Recombinational repair of E.coli chromosomal DNA involves as well other proteins: RecA, RecF, RecJ, RecO, RecR, and RuvC.; exonuclease VIII complement(1304869..1307469) Escherichia coli BW2952 7955912 YP_002926382.1 CDS racC NC_012759.1 1307571 1307846 R Rac prophage hypothetical protein; hypothetical protein complement(1307571..1307846) Escherichia coli BW2952 7955894 YP_002926383.1 CDS ydaE NC_012759.1 1307921 1308091 R MG1655 equivalent: b4526; Rac prophage protein complement(1307921..1308091) Escherichia coli BW2952 7955905 YP_002926384.1 CDS kil NC_012759.1 1308091 1308312 R Rac prophage Kil protein; Kil overexpression leads to morphological defects and inhibits cell division; FtsZ inhibitor protein complement(1308091..1308312) Escherichia coli BW2952 7955891 YP_002926385.1 CDS sieB NC_012759.1 1308754 1309242 D MG1655 equivalent: b1353; Rac prophage; phage superinfection exclusion protein 1308754..1309242 Escherichia coli BW2952 7955895 YP_002926386.1 CDS ydaF NC_012759.1 1309239 1309394 R MG1655 equivalent: b4527; Rac prophage protein complement(1309239..1309394) Escherichia coli BW2952 7955897 YP_002926387.1 CDS ydaG NC_012759.1 1309405 1309539 R MG1655 equivalent: b1355; Rac prophage protein complement(1309405..1309539) Escherichia coli BW2952 7955907 YP_002926388.1 CDS racR NC_012759.1 1309848 1310324 R MG1655 equivalent: b1356; Rac prophage; putative DNA-binding transcriptional regulator complement(1309848..1310324) Escherichia coli BW2952 7955906 YP_002926389.1 CDS ydaS NC_012759.1 1310448 1310744 D MG1655 equivalent: b1357; Rac prophage; putative DNA-binding transcriptional regulator 1310448..1310744 Escherichia coli BW2952 7955900 YP_002926390.1 CDS ydaT NC_012759.1 1310767 1311189 D MG1655 equivalent: b1358; Rac prophage protein 1310767..1311189 Escherichia coli BW2952 7955902 YP_002926391.1 CDS ydaU NC_012759.1 1311202 1312059 D MG1655 equivalent: b1359; Rac prophage protein 1311202..1312059 Escherichia coli BW2952 7955908 YP_002926392.1 CDS ydaV NC_012759.1 1312066 1312812 D MG1655 equivalent: b1360; putative replication protein 1312066..1312812 Escherichia coli BW2952 7955892 YP_002926393.1 CDS rzoR NC_012759.1 1313483 1313668 D MG1655 equivalent: b4528; Rac prophage; putative lipoprotein 1313483..1313668 Escherichia coli BW2952 7955899 YP_002926394.1 CDS trkG NC_012759.1 1313865 1315322 D MG1655 equivalent: b1363; Rac prophage; potassium transporter subunit 1313865..1315322 Escherichia coli BW2952 7955903 YP_002926395.1 CDS ynaK NC_012759.1 1315460 1315723 D MG1655 equivalent: b1365; Rac prophage protein 1315460..1315723 Escherichia coli BW2952 7955898 YP_002926396.1 CDS insH NC_012759.1 1317829 1318809 R MG1655 equivalent: b1370; IS5 transposase and trans-activator complement(1317829..1318809) Escherichia coli BW2952 7955893 YP_002926397.1 CDS stfR NC_012759.1 1319132 1322494 D MG1655 equivalent: b1372; Rac prophage; putative tail fiber protein 1319132..1322494 Escherichia coli BW2952 7954039 YP_002926398.1 CDS tfaR NC_012759.1 1322494 1323069 D MG1655 equivalent: b1373; Rac prophage; putative tail fiber assembly protein 1322494..1323069 Escherichia coli BW2952 7955911 YP_002926399.1 CDS pinR NC_012759.1 1323167 1323757 R MG1655 equivalent: b1374; Rac prophage; putative site-specific recombinase complement(1323167..1323757) Escherichia coli BW2952 7955910 YP_002926400.1 CDS ynaE NC_012759.1 1324074 1324340 R MG1655 equivalent: b1375; Rac prophage; putative DNA-binding transcriptional regulator complement(1324074..1324340) Escherichia coli BW2952 7955909 YP_002926401.1 CDS uspF NC_012759.1 1325268 1325702 R MG1655 equivalent: b1376; stress-induced protein, ATP-binding protein complement(1325268..1325702) Escherichia coli BW2952 7955901 YP_002926402.1 CDS ompN NC_012759.1 1325843 1326976 R MG1655 equivalent: b1377; outer membrane pore protein N, non-specific complement(1325843..1326976) Escherichia coli BW2952 7956074 YP_002926403.1 CDS ydbK NC_012759.1 1327343 1330867 R MG1655 equivalent: b1378; pyruvate-flavodoxin oxidoreductase complement(1327343..1330867) Escherichia coli BW2952 7952176 YP_002926404.1 CDS ydbJ NC_012759.1 1331141 1331407 D MG1655 equivalent: b4529; hypothetical protein 1331141..1331407 Escherichia coli BW2952 7953727 YP_002926405.1 CDS hslJ NC_012759.1 1331404 1331826 R MG1655 equivalent: b1379; heat-inducible protein complement(1331404..1331826) Escherichia coli BW2952 7955528 YP_002926406.1 CDS ldhA NC_012759.1 1331937 1332926 R MG1655 equivalent: b1380; fermentative D-lactate dehydrogenase, NAD-dependent complement(1331937..1332926) Escherichia coli BW2952 7953895 YP_002926407.1 CDS ydbH NC_012759.1 1333134 1335773 D MG1655 equivalent: b1381; hypothetical protein 1333134..1335773 Escherichia coli BW2952 7953563 YP_002926408.1 CDS ynbE NC_012759.1 1335770 1335955 D MG1655 equivalent: b1382; putative lipoprotein 1335770..1335955 Escherichia coli BW2952 7955464 YP_002926409.1 CDS ydbL NC_012759.1 1335963 1336289 D MG1655 equivalent: b1383; hypothetical protein 1335963..1336289 Escherichia coli BW2952 7955114 YP_002926410.1 CDS feaR NC_012759.1 1336461 1337366 R activator of genes involved in phenylacetic acid catabolism; DNA-binding transcriptional activator FeaR complement(1336461..1337366) Escherichia coli BW2952 7952964 YP_002926411.1 CDS feaB NC_012759.1 1337602 1339101 D MG1655 equivalent: b1385; phenylacetaldehyde dehydrogenase 1337602..1339101 Escherichia coli BW2952 7953405 YP_002926412.1 CDS tynA NC_012759.1 1339159 1341432 R catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine; tyramine oxidase complement(1339159..1341432) Escherichia coli BW2952 7954506 YP_002926413.1 CDS maoC NC_012759.1 1341680 1343725 R catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase complement(1341680..1343725) Escherichia coli BW2952 7956220 YP_002926414.1 CDS paaA NC_012759.1 1344010 1344939 D with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; phenylacetate-CoA oxygenase subunit PaaA 1344010..1344939 Escherichia coli BW2952 7953656 YP_002926415.1 CDS paaB NC_012759.1 1344951 1345238 D with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation; phenylacetate-CoA oxygenase subunit PaaB 1344951..1345238 Escherichia coli BW2952 7955167 YP_002926416.1 CDS paaC NC_012759.1 1345247 1345993 D MG1655 equivalent: b1390; putative multicomponent oxygenase/reductase subunit for phenylacetic acid degradation 1345247..1345993 Escherichia coli BW2952 7955168 YP_002926417.1 CDS paaD NC_012759.1 1346002 1346505 D MG1655 equivalent: b1391; putative multicomponent oxygenase/reductase subunit for phenylacetic acid degradation 1346002..1346505 Escherichia coli BW2952 7955169 YP_002926418.1 CDS paaE NC_012759.1 1346513 1347583 D MG1655 equivalent: b1392; putative multicomponent oxygenase/reductase subunit for phenylacetic acid degradation 1346513..1347583 Escherichia coli BW2952 7955170 YP_002926419.1 CDS paaF NC_012759.1 1347580 1348347 D MG1655 equivalent: b1393; enoyl-CoA hydratase-isomerase 1347580..1348347 Escherichia coli BW2952 7955171 YP_002926420.1 CDS paaG NC_012759.1 1348347 1349135 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1348347..1349135 Escherichia coli BW2952 7953524 YP_002926421.1 CDS paaH NC_012759.1 1349137 1350564 D converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; 3-hydroxyacyl-CoA dehydrogenase 1349137..1350564 Escherichia coli BW2952 7952415 YP_002926422.1 CDS paaI NC_012759.1 1350554 1350976 D MG1655 equivalent: b1396; putative thioesterase 1350554..1350976 Escherichia coli BW2952 7952304 YP_002926423.1 CDS paaJ NC_012759.1 1350976 1352181 D catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; beta-ketoadipyl CoA thiolase 1350976..1352181 Escherichia coli BW2952 7955620 YP_002926424.1 CDS paaK NC_012759.1 1352208 1353521 D MG1655 equivalent: b1398; phenylacetyl-CoA ligase 1352208..1353521 Escherichia coli BW2952 7954668 YP_002926425.1 CDS paaX NC_012759.1 1353622 1354572 D MG1655 equivalent: b1399; DNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive 1353622..1354572 Escherichia coli BW2952 7954507 YP_002926426.1 CDS paaY NC_012759.1 1354554 1355144 D MG1655 equivalent: b1400; putative hexapeptide repeat acetyltransferase 1354554..1355144 Escherichia coli BW2952 7953475 YP_002926427.1 CDS insD NC_012759.1 1358004 1358909 R IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD complement(1358004..1358909) Escherichia coli BW2952 7954943 YP_002926428.1 CDS insC NC_012759.1 1358867 1359232 R IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein complement(1358867..1359232) Escherichia coli BW2952 7954077 YP_002926429.1 CDS insI NC_012759.1 1359441 1360592 D MG1655 equivalent: b1404; KpLE2 phage-like element; IS30 transposase 1359441..1360592 Escherichia coli BW2952 7954071 YP_002926430.1 CDS ydbC NC_012759.1 1364304 1365164 D MG1655 equivalent: b1406; putative oxidoreductase 1364304..1365164 Escherichia coli BW2952 7954085 YP_002926431.1 CDS ydbD NC_012759.1 1365227 1367533 D MG1655 equivalent: b1407; hypothetical protein 1365227..1367533 Escherichia coli BW2952 7955255 YP_002926432.1 CDS ynbA NC_012759.1 1367704 1368309 D MG1655 equivalent: b1408; putative inner membrane protein 1367704..1368309 Escherichia coli BW2952 7955465 YP_002926433.1 CDS ynbB NC_012759.1 1368309 1369205 D MG1655 equivalent: b1409; putative CDP-diglyceride synthase 1368309..1369205 Escherichia coli BW2952 7955040 YP_002926434.1 CDS ynbC NC_012759.1 1369221 1370978 D MG1655 equivalent: b1410; putative hydrolase 1369221..1370978 Escherichia coli BW2952 7954685 YP_002926435.1 CDS ynbD NC_012759.1 1370992 1372284 D MG1655 equivalent: b1411; putative phosphatase, inner membrane protein 1370992..1372284 Escherichia coli BW2952 7954965 YP_002926436.1 CDS azoR NC_012759.1 1372338 1372943 R FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase complement(1372338..1372943) Escherichia coli BW2952 7955312 YP_002926437.1 CDS hrpA NC_012759.1 1373144 1377046 D involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1373144..1377046 Escherichia coli BW2952 7954369 YP_002926438.1 CDS ydcF NC_012759.1 1377318 1378118 D MG1655 equivalent: b1414; hypothetical protein 1377318..1378118 Escherichia coli BW2952 7952533 YP_002926439.1 CDS aldA NC_012759.1 1378315 1379754 D NAD-linked; aldehyde dehydrogenase A 1378315..1379754 Escherichia coli BW2952 7952965 YP_002926440.1 CDS cybB NC_012759.1 1380985 1381515 D B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1380985..1381515 Escherichia coli BW2952 7952443 YP_002926441.1 CDS ydcA NC_012759.1 1381760 1381933 D MG1655 equivalent: b1419; hypothetical protein 1381760..1381933 Escherichia coli BW2952 7952082 YP_002926442.1 CDS hokB NC_012759.1 1382005 1382154 R MG1655 equivalent: b4428; small toxic polypeptide complement(1382005..1382154) Escherichia coli BW2952 7955466 YP_002926443.1 CDS mokB NC_012759.1 1382045 1382212 R MG1655 equivalent: b1420; regulatory peptide complement(1382045..1382212) Escherichia coli BW2952 7956156 YP_002926444.1 CDS trg NC_012759.1 1382553 1384193 D MG1655 equivalent: b1421; methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor 1382553..1384193 Escherichia coli BW2952 7952177 YP_002926445.1 CDS ydcI NC_012759.1 1384231 1385154 R MG1655 equivalent: b1422; putative DNA-binding transcriptional regulator complement(1384231..1385154) Escherichia coli BW2952 7954250 YP_002926446.1 CDS ydcJ NC_012759.1 1385371 1386714 D MG1655 equivalent: b1423; hypothetical protein 1385371..1386714 Escherichia coli BW2952 7954756 YP_002926447.1 CDS mdoD NC_012759.1 1386939 1388594 D involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1386939..1388594 Escherichia coli BW2952 7952966 YP_002926448.1 CDS ydcH NC_012759.1 1388734 1388958 D MG1655 equivalent: b1426; hypothetical protein 1388734..1388958 Escherichia coli BW2952 7953791 YP_002926449.1 CDS rimL NC_012759.1 1389021 1389560 D MG1655 equivalent: b1427; ribosomal-protein-L7/L12-serine acetyltransferase 1389021..1389560 Escherichia coli BW2952 7955467 YP_002926450.1 CDS ydcK NC_012759.1 1389552 1390532 R MG1655 equivalent: b1428; putative enzyme complement(1389552..1390532) Escherichia coli BW2952 7955975 YP_002926451.1 CDS tehA NC_012759.1 1390656 1391648 D MG1655 equivalent: b1429; potassium-tellurite ethidium and proflavin transporter 1390656..1391648 Escherichia coli BW2952 7954840 YP_002926452.1 CDS tehB NC_012759.1 1391645 1392238 D with TehA confers resistance to tellurite; tellurite resistance protein TehB 1391645..1392238 Escherichia coli BW2952 7954580 YP_002926453.1 CDS ydcL NC_012759.1 1392540 1393208 D MG1655 equivalent: b1431; putative lipoprotein 1392540..1393208 Escherichia coli BW2952 7955579 YP_002926454.1 CDS ydcM NC_012759.1 1393740 1394948 D MG1655 equivalent: b1432; putative transposase 1393740..1394948 Escherichia coli BW2952 7955115 YP_002926455.1 CDS ydcO NC_012759.1 1394988 1396163 R MG1655 equivalent: b1433; putative benzoate transporter complement(1394988..1396163) Escherichia coli BW2952 7955740 YP_002926456.1 CDS ydcN NC_012759.1 1396255 1396791 D MG1655 equivalent: b1434; putative DNA-binding transcriptional regulator 1396255..1396791 Escherichia coli BW2952 7954667 YP_002926457.1 CDS ydcP NC_012759.1 1396864 1398825 D MG1655 equivalent: b1435; putative peptidase 1396864..1398825 Escherichia coli BW2952 7954797 YP_002926458.1 CDS yncJ NC_012759.1 1398917 1399147 R MG1655 equivalent: b1436; hypothetical protein complement(1398917..1399147) Escherichia coli BW2952 7955279 YP_002926459.1 CDS yncN NC_012759.1 1399369 1399545 D MG1655 equivalent: b4532; hypothetical protein 1399369..1399545 Escherichia coli BW2952 7955361 YP_002926460.1 CDS ydcQ NC_012759.1 1399591 1400007 D MG1655 equivalent: b1438; putative DNA-binding transcriptional regulator 1399591..1400007 Escherichia coli BW2952 7955529 YP_002926461.1 CDS ydcR NC_012759.1 1400086 1401492 D MG1655 equivalent: b1439; fused putative DNA-binding transcriptional regulator/putative amino transferase 1400086..1401492 Escherichia coli BW2952 7954798 YP_002926462.1 CDS ydcS NC_012759.1 1401737 1402882 D MG1655 equivalent: b1440; putative spermidine/putrescine transporter subunit 1401737..1402882 Escherichia coli BW2952 7953711 YP_002926463.1 CDS ydcT NC_012759.1 1402900 1403913 D MG1655 equivalent: b1441; putative spermidine/putrescine transporter subunit 1402900..1403913 Escherichia coli BW2952 7955594 YP_002926464.1 CDS ydcU NC_012759.1 1403914 1404855 D MG1655 equivalent: b1442; putative spermidine/putrescine transporter subunit 1403914..1404855 Escherichia coli BW2952 7955595 YP_002926465.1 CDS ydcV NC_012759.1 1404845 1405639 D MG1655 equivalent: b1443; putative spermidine/putrescine transporter subunit 1404845..1405639 Escherichia coli BW2952 7955596 YP_002926466.1 CDS ydcW NC_012759.1 1405661 1407085 D catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1405661..1407085 Escherichia coli BW2952 7955597 YP_002926467.1 CDS yncL NC_012759.1 1407182 1407277 R MG1655 equivalent: b4598; hypothetical protein complement(1407182..1407277) Escherichia coli BW2952 7954220 YP_002926468.1 CDS ydcX NC_012759.1 1407472 1407645 D MG1655 equivalent: b1445; putative inner membrane protein 1407472..1407645 Escherichia coli BW2952 7953966 YP_002926469.1 CDS ydcY NC_012759.1 1407731 1407964 D MG1655 equivalent: b1446; hypothetical protein 1407731..1407964 Escherichia coli BW2952 7955041 YP_002926470.1 CDS ydcZ NC_012759.1 1407965 1408414 R MG1655 equivalent: b1447; putative inner membrane protein complement(1407965..1408414) Escherichia coli BW2952 7955468 YP_002926471.1 CDS yncA NC_012759.1 1408411 1408929 R MG1655 equivalent: b1448; putative acyltransferase with acyl-CoA N-acyltransferase domain complement(1408411..1408929) Escherichia coli BW2952 7954995 YP_002926472.1 CDS yncB NC_012759.1 1409086 1410147 D MG1655 equivalent: b1449; putative oxidoreductase, Zn-dependent and NAD(P)-binding 1409086..1410147 Escherichia coli BW2952 7954615 YP_002926473.1 CDS yncC NC_012759.1 1410345 1411010 D MG1655 equivalent: b1450; putative DNA-binding transcriptional regulator 1410345..1411010 Escherichia coli BW2952 7955264 YP_002926474.1 CDS yncD NC_012759.1 1411046 1413148 R MG1655 equivalent: b1451; putative iron outer membrane transporter complement(1411046..1413148) Escherichia coli BW2952 7954799 YP_002926475.1 CDS yncE NC_012759.1 1413390 1414451 D MG1655 equivalent: b1452; hypothetical protein 1413390..1414451 Escherichia coli BW2952 7955088 YP_002926476.1 CDS ansP NC_012759.1 1414564 1416063 R MG1655 equivalent: b1453; L-asparagine transporter complement(1414564..1416063) Escherichia coli BW2952 7952967 YP_002926477.1 CDS yncG NC_012759.1 1416330 1416947 D MG1655 equivalent: b1454; putative enzyme 1416330..1416947 Escherichia coli BW2952 7954121 YP_002926478.1 CDS yncH NC_012759.1 1417023 1417235 D MG1655 equivalent: b1455; hypothetical protein 1417023..1417235 Escherichia coli BW2952 7954844 YP_002926479.1 CDS ydcD NC_012759.1 1420005 1420487 D MG1655 equivalent: b1457; hypothetical protein 1420005..1420487 Escherichia coli BW2952 7955469 YP_002926480.1 CDS ydcC NC_012759.1 1421899 1423035 D MG1655 equivalent: b1460; hypothetical protein 1421899..1423035 Escherichia coli BW2952 7955470 YP_002926481.1 CDS pptA NC_012759.1 1423135 1423368 D 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 1423135..1423368 Escherichia coli BW2952 7952968 YP_002926482.1 CDS yddH NC_012759.1 1423365 1423934 R MG1655 equivalent: b1462; hypothetical protein complement(1423365..1423934) Escherichia coli BW2952 7952335 YP_002926483.1 CDS nhoA NC_012759.1 1424107 1424952 D MG1655 equivalent: b1463; N-hydroxyarylamine O-acetyltransferase 1424107..1424952 Escherichia coli BW2952 7952794 YP_002926484.1 CDS yddE NC_012759.1 1425048 1425941 R MG1655 equivalent: b1464; hypothetical protein complement(1425048..1425941) Escherichia coli BW2952 7954376 YP_002926485.1 CDS narV NC_012759.1 1426020 1426700 R MG1655 equivalent: b1465; nitrate reductase 2 (NRZ), gamma subunit complement(1426020..1426700) Escherichia coli BW2952 7952795 YP_002926486.1 CDS narW NC_012759.1 1426697 1427392 R MG1655 equivalent: b1466; nitrate reductase 2 (NRZ), delta subunit (assembly subunit) complement(1426697..1427392) Escherichia coli BW2952 7954393 YP_002926487.1 CDS narY NC_012759.1 1427392 1428936 R MG1655 equivalent: b1467; nitrate reductase 2 (NRZ), beta subunit complement(1427392..1428936) Escherichia coli BW2952 7954392 YP_002926488.1 CDS narZ NC_012759.1 1428933 1432673 R MG1655 equivalent: b1468; nitrate reductase 2 (NRZ), alpha subunit complement(1428933..1432673) Escherichia coli BW2952 7954391 YP_002926489.1 CDS narU NC_012759.1 1432755 1434143 R MG1655 equivalent: b1469; nitrate/nitrite transporter complement(1432755..1434143) Escherichia coli BW2952 7954390 YP_002926490.1 CDS yddJ NC_012759.1 1434467 1434802 R MG1655 equivalent: b1470; hypothetical protein complement(1434467..1434802) Escherichia coli BW2952 7954397 YP_002926491.1 CDS yddG NC_012759.1 1436371 1437252 R MG1655 equivalent: b1473; hypothetical protein complement(1436371..1437252) Escherichia coli BW2952 7955362 YP_002926492.1 CDS fdnG NC_012759.1 1437484 1440531 D MG1655 equivalent: b1474; formate dehydrogenase-N subunit alpha, nitrate-inducible 1437484..1440531 Escherichia coli BW2952 7955150 YP_002926493.1 CDS fdnH NC_012759.1 1440544 1441428 D MG1655 equivalent: b1475; formate dehydrogenase-N, Fe-S (beta) subunit, nitrate-inducible 1440544..1441428 Escherichia coli BW2952 7953619 YP_002926494.1 CDS fdnI NC_012759.1 1441421 1442074 D nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1441421..1442074 Escherichia coli BW2952 7953621 YP_002926495.1 CDS yddM NC_012759.1 1442481 1442765 R MG1655 equivalent: b1477; putative DNA-binding transcriptional regulator complement(1442481..1442765) Escherichia coli BW2952 7953620 YP_002926496.1 CDS adhP NC_012759.1 1442911 1443921 R similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase complement(1442911..1443921) Escherichia coli BW2952 7954757 YP_002926497.1 CDS maeA NC_012759.1 1444055 1445752 R malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase complement(1444055..1445752) Escherichia coli BW2952 7953533 YP_002926498.1 CDS rpsV NC_012759.1 1445909 1446046 R protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase; 30S ribosomal subunit S22 complement(1445909..1446046) Escherichia coli BW2952 7954197 YP_002926499.1 CDS bdm NC_012759.1 1446148 1446363 R MG1655 equivalent: b1481; biofilm-dependent modulation protein complement(1446148..1446363) Escherichia coli BW2952 7952286 YP_002926500.1 CDS osmC NC_012759.1 1446708 1447139 D MG1655 equivalent: b1482; osmotically inducible, stress-inducible membrane protein 1446708..1447139 Escherichia coli BW2952 7952578 YP_002926501.1 CDS ddpF NC_012759.1 1447195 1448121 R MG1655 equivalent: b1483; D-ala-D-ala transporter subunit complement(1447195..1448121) Escherichia coli BW2952 7954434 YP_002926502.1 CDS ddpD NC_012759.1 1448114 1449100 R MG1655 equivalent: b1484; D-ala-D-ala transporter subunit complement(1448114..1449100) Escherichia coli BW2952 7953210 YP_002926503.1 CDS ddpC NC_012759.1 1449097 1449993 R MG1655 equivalent: b1485; ATP-dependent peptide transporter membrane subunit complement(1449097..1449993) Escherichia coli BW2952 7953211 YP_002926504.1 CDS ddpB NC_012759.1 1449990 1451012 R MG1655 equivalent: b1486; D-ala-D-ala transporter subunit complement(1449990..1451012) Escherichia coli BW2952 7953212 YP_002926505.1 CDS ddpA NC_012759.1 1451014 1452564 R MG1655 equivalent: b1487; D-ala-D-a la transporter subunit complement(1451014..1452564) Escherichia coli BW2952 7953213 YP_002926506.1 CDS ddpX NC_012759.1 1452578 1453159 R catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis; D-alanyl-D-alanine dipeptidase complement(1452578..1453159) Escherichia coli BW2952 7953208 YP_002926507.1 CDS dos NC_012759.1 1453417 1455816 R heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate; cAMP phosphodiesterase complement(1453417..1455816) Escherichia coli BW2952 7953209 YP_002926508.1 CDS yddV NC_012759.1 1455841 1457223 R MG1655 equivalent: b1490; putative diguanylate cyclase complement(1455841..1457223) Escherichia coli BW2952 7952590 YP_002926509.1 CDS yddW NC_012759.1 1457587 1458906 R MG1655 equivalent: b1491; lipoprotein complement(1457587..1458906) Escherichia coli BW2952 7954721 YP_002926510.1 CDS gadC NC_012759.1 1459037 1460572 R MG1655 equivalent: b1492; putative glutamate:gamma-aminobutyric acid antiporter complement(1459037..1460572) Escherichia coli BW2952 7955123 YP_002926511.1 CDS gadB NC_012759.1 1460728 1462128 R MG1655 equivalent: b1493; glutamate decarboxylase complement(1460728..1462128) Escherichia coli BW2952 7954922 YP_002926512.1 CDS pqqL NC_012759.1 1462490 1465285 R MG1655 equivalent: b1494; putative peptidase complement(1462490..1465285) Escherichia coli BW2952 7953819 YP_002926513.1 CDS yddB NC_012759.1 1465330 1467702 R MG1655 equivalent: b1495; putative porin protein complement(1465330..1467702) Escherichia coli BW2952 7955271 YP_002926514.1 CDS yddA NC_012759.1 1467740 1469425 R MG1655 equivalent: b1496; fused putative multidrug transporter subunits of ABC superfamily: membrane component/ATP-binding component complement(1467740..1469425) Escherichia coli BW2952 7955328 YP_002926515.1 CDS ydeM NC_012759.1 1469716 1470873 R MG1655 equivalent: b1497; hypothetical protein complement(1469716..1470873) Escherichia coli BW2952 7953718 YP_002926516.1 CDS ydeN NC_012759.1 1470925 1472607 R MG1655 equivalent: b1498; hypothetical protein complement(1470925..1472607) Escherichia coli BW2952 7952796 YP_002926517.1 CDS ydeO NC_012759.1 1473009 1473770 R regulates the cellular response to acid resistance; transcriptional regulator YdeO complement(1473009..1473770) Escherichia coli BW2952 7952797 YP_002926518.1 CDS yneN NC_012759.1 1473845 1474042 R MG1655 equivalent: b1500; two component system connector membrane protein, EvgSA to PhoQP complement(1473845..1474042) Escherichia coli BW2952 7954743 YP_002926519.1 CDS ydeP NC_012759.1 1474290 1476569 R in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family; putative oxidoreductase complement(1474290..1476569) Escherichia coli BW2952 7956219 YP_002926520.1 CDS ydeQ NC_012759.1 1476903 1477817 R MG1655 equivalent: b1502; putative fimbrial-like adhesin protein complement(1476903..1477817) Escherichia coli BW2952 7955224 YP_002926521.1 CDS ydeR NC_012759.1 1477876 1478379 R MG1655 equivalent: b1503; putative fimbrial-like adhesin protein complement(1477876..1478379) Escherichia coli BW2952 7954883 YP_002926522.1 CDS ydeS NC_012759.1 1478392 1478922 R MG1655 equivalent: b1504; putative fimbrial-like adhesin protein complement(1478392..1478922) Escherichia coli BW2952 7954884 YP_002926523.1 CDS hipA NC_012759.1 1480937 1482259 R MG1655 equivalent: b1507; regulator with hipB complement(1480937..1482259) Escherichia coli BW2952 7954885 YP_002926524.1 CDS hipB NC_012759.1 1482259 1482525 R MG1655 equivalent: b1508; DNA-binding transcriptional regulator HipB complement(1482259..1482525) Escherichia coli BW2952 7955927 YP_002926525.1 CDS ydeU NC_012759.1 1482748 1484148 R MG1655 equivalent: b1509; hypothetical protein complement(1482748..1484148) Escherichia coli BW2952 7953439 YP_002926526.1 CDS ydeK NC_012759.1 1484192 1488169 R MG1655 equivalent: b1510; putative lipoprotein complement(1484192..1488169) Escherichia coli BW2952 7952798 YP_002926527.1 CDS lsrK NC_012759.1 1488700 1490292 R MG1655 equivalent: b1511; autoinducer-2 (AI-2) kinase complement(1488700..1490292) Escherichia coli BW2952 7955107 YP_002926528.1 CDS lsrR NC_012759.1 1490371 1491324 R MG1655 equivalent: b1512; lsr operon transcriptional repressor complement(1490371..1491324) Escherichia coli BW2952 7952538 YP_002926529.1 CDS lsrA NC_012759.1 1491573 1493108 D MG1655 equivalent: b1513; fused AI2 transporter subunits of ABC superfamily: ATP-binding components 1491573..1493108 Escherichia coli BW2952 7954173 YP_002926530.1 CDS lsrC NC_012759.1 1493102 1494130 D MG1655 equivalent: b1514; AI2 transporter 1493102..1494130 Escherichia coli BW2952 7953655 YP_002926531.1 CDS lsrD NC_012759.1 1494130 1495122 D MG1655 equivalent: b1515; AI2 transporter 1494130..1495122 Escherichia coli BW2952 7952435 YP_002926532.1 CDS lsrB NC_012759.1 1495134 1496156 D MG1655 equivalent: b1516; AI2 transporter 1495134..1496156 Escherichia coli BW2952 7952436 YP_002926533.1 CDS lsrF NC_012759.1 1496183 1497058 D MG1655 equivalent: b1517; aldolase 1496183..1497058 Escherichia coli BW2952 7952437 YP_002926534.1 CDS lsrG NC_012759.1 1497082 1497372 D MG1655 equivalent: b1518; autoinducer-2 (AI-2) modifying protein LsrG 1497082..1497372 Escherichia coli BW2952 7955826 YP_002926535.1 CDS tam NC_012759.1 1497429 1498187 D catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 1497429..1498187 Escherichia coli BW2952 7952539 YP_002926536.1 CDS yneE NC_012759.1 1498191 1499105 R MG1655 equivalent: b1520; hypothetical protein complement(1498191..1499105) Escherichia coli BW2952 7956163 YP_002926537.1 CDS uxaB NC_012759.1 1499312 1500763 R catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase complement(1499312..1500763) Escherichia coli BW2952 7952670 YP_002926538.1 CDS yneF NC_012759.1 1500990 1501937 R MG1655 equivalent: b1522; putative diguanylate cyclase complement(1500990..1501937) Escherichia coli BW2952 7952462 YP_002926539.1 CDS yneG NC_012759.1 1502049 1502408 R MG1655 equivalent: b1523; hypothetical protein complement(1502049..1502408) Escherichia coli BW2952 7954722 YP_002926540.1 CDS yneH NC_012759.1 1502408 1503334 R catalyzes the formation of glutamate from glutamine; glutaminase complement(1502408..1503334) Escherichia coli BW2952 7952799 YP_002926541.1 CDS sad NC_012759.1 1503398 1504786 R in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; putative succinate-semialdehyde dehydrogenase complement(1503398..1504786) Escherichia coli BW2952 7954923 YP_002926542.1 CDS yneJ NC_012759.1 1504887 1505768 D MG1655 equivalent: b1526; putative DNA-binding transcriptional regulator 1504887..1505768 Escherichia coli BW2952 7954627 YP_002926543.1 CDS yneK NC_012759.1 1505846 1506961 D MG1655 equivalent: b1527; hypothetical protein 1505846..1506961 Escherichia coli BW2952 7954800 YP_002926544.1 CDS ydeA NC_012759.1 1507111 1508301 D MG1655 equivalent: b1528; sugar efflux transporter 1507111..1508301 Escherichia coli BW2952 7955471 YP_002926545.1 CDS marC NC_012759.1 1508326 1508991 R protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC complement(1508326..1508991) Escherichia coli BW2952 7954657 YP_002926546.1 CDS marR NC_012759.1 1509203 1509637 D Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 1509203..1509637 Escherichia coli BW2952 7952800 YP_002926547.1 CDS marA NC_012759.1 1509657 1510040 D transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 1509657..1510040 Escherichia coli BW2952 7953474 YP_002926548.1 CDS marB NC_012759.1 1510072 1510290 D MG1655 equivalent: b1532; hypothetical protein 1510072..1510290 Escherichia coli BW2952 7953403 YP_002926549.1 CDS eamA NC_012759.1 1510321 1511220 R MG1655 equivalent: b1533; O-acetylserine/cysteine export protein complement(1510321..1511220) Escherichia coli BW2952 7955472 YP_002926550.1 CDS ydeE NC_012759.1 1511415 1512602 D YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; putative MFS-type transporter YdeE 1511415..1512602 Escherichia coli BW2952 7953181 YP_002926551.1 CDS yneM NC_012759.1 1512729 1512824 D MG1655 equivalent: b4599; hypothetical protein 1512729..1512824 Escherichia coli BW2952 7955685 YP_002926552.1 CDS ydeH NC_012759.1 1513043 1513933 R MG1655 equivalent: b1535; hypothetical protein complement(1513043..1513933) Escherichia coli BW2952 7953979 YP_002926553.1 CDS ydeI NC_012759.1 1514188 1514580 R MG1655 equivalent: b1536; hypothetical protein complement(1514188..1514580) Escherichia coli BW2952 7952801 YP_002926554.1 CDS ydeJ NC_012759.1 1514856 1515374 D MG1655 equivalent: b1537; competence damage-inducible protein A 1514856..1515374 Escherichia coli BW2952 7952802 YP_002926555.1 CDS dcp NC_012759.1 1515418 1517463 R MG1655 equivalent: b1538; dipeptidyl carboxypeptidase II complement(1515418..1517463) Escherichia coli BW2952 7952969 YP_002926556.1 CDS ydfG NC_012759.1 1517600 1518346 D NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 1517600..1518346 Escherichia coli BW2952 7953269 YP_002926557.1 CDS ydfH NC_012759.1 1518435 1519121 D MG1655 equivalent: b1540; putative DNA-binding transcriptional regulator 1518435..1519121 Escherichia coli BW2952 7954110 YP_002926558.1 CDS ydfZ NC_012759.1 1519298 1519501 D MG1655 equivalent: b1541; hypothetical protein 1519298..1519501 Escherichia coli BW2952 7954801 YP_002926559.1 CDS ydfI NC_012759.1 1519536 1520996 R MG1655 equivalent: b1542; putative mannonate dehydrogenase complement(1519536..1520996) Escherichia coli BW2952 7952970 YP_002926560.1 CDS ydfK NC_012759.1 1523122 1523388 D MG1655 equivalent: b1544; Qin prophage; putative DNA-binding transcriptional regulator 1523122..1523388 Escherichia coli BW2952 7955133 YP_002926561.1 CDS pinQ NC_012759.1 1523705 1524295 D MG1655 equivalent: b1545; Qin prophage; putative site-specific recombinase 1523705..1524295 Escherichia coli BW2952 7955862 YP_002926562.1 CDS tfaQ NC_012759.1 1524393 1524968 R MG1655 equivalent: b1546; Qin prophage; tail fiber assembly protein complement(1524393..1524968) Escherichia coli BW2952 7955880 YP_002926563.1 CDS ydfN NC_012759.1 1524968 1525930 R MG1655 equivalent: b1547; Qin prophage; side tail fiber assembly protein complement(1524968..1525930) Escherichia coli BW2952 7955881 YP_002926564.1 CDS ynfO NC_012759.1 1526839 1527072 D MG1655 equivalent: b4533; hypothetical protein 1526839..1527072 Escherichia coli BW2952 7955879 YP_002926565.1 CDS ydfO NC_012759.1 1527130 1527540 D MG1655 equivalent: b1549; Qin prophage protein 1527130..1527540 Escherichia coli BW2952 7953987 YP_002926566.1 CDS gnsB NC_012759.1 1527692 1527865 R MG1655 equivalent: b1550; Qin prophage protein complement(1527692..1527865) Escherichia coli BW2952 7955871 YP_002926567.1 CDS ynfN NC_012759.1 1528037 1528192 R MG1655 equivalent: b1551; Qin prophage protein complement(1528037..1528192) Escherichia coli BW2952 7955864 YP_002926568.1 CDS cspI NC_012759.1 1528538 1528750 R MG1655 equivalent: b1552; Qin prophage; cold shock protein complement(1528538..1528750) Escherichia coli BW2952 7955865 YP_002926569.1 CDS ydfP NC_012759.1 1529113 1529610 R MG1655 equivalent: b1553; Qin prophage protein complement(1529113..1529610) Escherichia coli BW2952 7955856 YP_002926570.1 CDS arrQ NC_012759.1 1529607 1530140 R MG1655 equivalent: b1554; Qin prophage; putative lysozyme complement(1529607..1530140) Escherichia coli BW2952 7955859 YP_002926571.1 CDS ydfR NC_012759.1 1530137 1530448 R MG1655 equivalent: b1555; Qin prophage protein complement(1530137..1530448) Escherichia coli BW2952 7955863 YP_002926572.1 CDS essQ NC_012759.1 1530453 1530668 R MG1655 equivalent: b1556; Qin prophage; putative S lysis protein complement(1530453..1530668) Escherichia coli BW2952 7955866 YP_002926573.1 CDS cspB NC_012759.1 1531422 1531637 R MG1655 equivalent: b1557; Qin prophage; cold shock protein complement(1531422..1531637) Escherichia coli BW2952 7955878 YP_002926574.1 CDS cspF NC_012759.1 1531938 1532150 D MG1655 equivalent: b1558; Qin prophage; cold shock protein 1531938..1532150 Escherichia coli BW2952 7955857 YP_002926575.1 CDS quuQ NC_012759.1 1532572 1533324 R MG1655 equivalent: b1559; Qin prophage; putative antitermination protein Q complement(1532572..1533324) Escherichia coli BW2952 7955858 YP_002926576.1 CDS ydfU NC_012759.1 1533338 1534285 R MG1655 equivalent: b1560; Qin prophage protein complement(1533338..1534285) Escherichia coli BW2952 7955861 YP_002926577.1 CDS rem NC_012759.1 1534734 1534985 R MG1655 equivalent: b1561; Qin prophage protein complement(1534734..1534985) Escherichia coli BW2952 7955867 YP_002926578.1 CDS hokD NC_012759.1 1535202 1535357 R MG1655 equivalent: b1562; Qin prophage; small toxic polypeptide complement(1535202..1535357) Escherichia coli BW2952 7955868 YP_002926579.1 CDS relE NC_012759.1 1535429 1535716 R MG1655 equivalent: b1563; Qin prophage; toxin of the RelE-RelB toxin-antitoxin system complement(1535429..1535716) Escherichia coli BW2952 7955882 YP_002926580.1 CDS relB NC_012759.1 1535716 1535955 R Qin prophage; bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor; bifunctional antitoxin/transcriptional repressor RelB complement(1535716..1535955) Escherichia coli BW2952 7955883 YP_002926581.1 CDS ydfV NC_012759.1 1535980 1536285 D MG1655 equivalent: b1565; Qin prophage protein 1535980..1536285 Escherichia coli BW2952 7955854 YP_002926582.1 CDS flxA NC_012759.1 1536488 1536820 D MG1655 equivalent: b1566; Qin prophage protein 1536488..1536820 Escherichia coli BW2952 7955872 YP_002926583.1 CDS ydfW NC_012759.1 1537205 1537432 R MG1655 equivalent: b1567; Qin prophage protein complement(1537205..1537432) Escherichia coli BW2952 7955873 YP_002926584.1 CDS ydfX NC_012759.1 1537429 1537719 R MG1655 equivalent: b1568; Qin prophage protein complement(1537429..1537719) Escherichia coli BW2952 7955869 YP_002926585.1 CDS dicC NC_012759.1 1537703 1537933 R MG1655 equivalent: b1569; DNA-binding transcriptional regulator DicC complement(1537703..1537933) Escherichia coli BW2952 7955870 YP_002926586.1 CDS dicA NC_012759.1 1538017 1538424 D The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown.; transcriptional repressor DicA 1538017..1538424 Escherichia coli BW2952 7955860 YP_002926587.1 CDS ydfA NC_012759.1 1538591 1538746 D MG1655 equivalent: b1571; Qin prophage protein 1538591..1538746 Escherichia coli BW2952 7955877 YP_002926588.1 CDS ydfB NC_012759.1 1538748 1538876 D MG1655 equivalent: b1572; Qin prophage protein 1538748..1538876 Escherichia coli BW2952 7955874 YP_002926589.1 CDS dicB NC_012759.1 1539692 1539880 D MG1655 equivalent: b1575; Qin prophage; cell division inhibition protein 1539692..1539880 Escherichia coli BW2952 7952178 YP_002926590.1 CDS ydfD NC_012759.1 1539877 1540068 D MG1655 equivalent: b1576; Qin prophage protein 1539877..1540068 Escherichia coli BW2952 7955855 YP_002926591.1 CDS rspB NC_012759.1 1542979 1543998 R MG1655 equivalent: b1580; putative dehydrogenase complement(1542979..1543998) Escherichia coli BW2952 7955876 YP_002926592.1 CDS rspA NC_012759.1 1544010 1545224 R MG1655 equivalent: b1581; putative dehydratase complement(1544010..1545224) Escherichia coli BW2952 7955258 YP_002926593.1 CDS ynfA NC_012759.1 1545430 1545756 R MG1655 equivalent: b1582; hypothetical protein complement(1545430..1545756) Escherichia coli BW2952 7954711 YP_002926594.1 CDS ynfB NC_012759.1 1545891 1546232 D MG1655 equivalent: b1583; hypothetical protein 1545891..1546232 Escherichia coli BW2952 7952671 YP_002926595.1 CDS speG NC_012759.1 1546267 1546827 D MG1655 equivalent: b1584; spermidine N1-acetyltransferase 1546267..1546827 Escherichia coli BW2952 7955473 YP_002926596.1 CDS ynfC NC_012759.1 1546830 1547540 R MG1655 equivalent: b1585; hypothetical protein complement(1546830..1547540) Escherichia coli BW2952 7956061 YP_002926597.1 CDS ynfD NC_012759.1 1547648 1547953 D MG1655 equivalent: b1586; hypothetical protein 1547648..1547953 Escherichia coli BW2952 7955363 YP_002926598.1 CDS ynfE NC_012759.1 1548152 1550578 D MG1655 equivalent: b1587; oxidoreductase subunit 1548152..1550578 Escherichia coli BW2952 7955474 YP_002926599.1 CDS ynfF NC_012759.1 1550639 1553062 D MG1655 equivalent: b1588; oxidoreductase subunit 1550639..1553062 Escherichia coli BW2952 7954456 YP_002926600.1 CDS ynfG NC_012759.1 1553073 1553690 D MG1655 equivalent: b1589; oxidoreductase, Fe-S subunit 1553073..1553690 Escherichia coli BW2952 7954457 YP_002926601.1 CDS ynfH NC_012759.1 1553692 1554546 D MG1655 equivalent: b1590; oxidoreductase, membrane subunit 1553692..1554546 Escherichia coli BW2952 7954459 YP_002926602.1 CDS dmsD NC_012759.1 1554589 1555203 D binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 1554589..1555203 Escherichia coli BW2952 7954460 YP_002926603.1 CDS clcB NC_012759.1 1555398 1556654 D MG1655 equivalent: b1592; putative voltage-gated ClC-type chloride channel ClcB 1555398..1556654 Escherichia coli BW2952 7956218 YP_002926604.1 CDS ynfK NC_012759.1 1556607 1557302 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; putative dithiobiotin synthetase complement(1556607..1557302) Escherichia coli BW2952 7955749 YP_002926605.1 CDS dgsA NC_012759.1 1557427 1558647 R MG1655 equivalent: b1594; DNA-binding transcriptional repressor complement(1557427..1558647) Escherichia coli BW2952 7954719 YP_002926606.1 CDS ynfL NC_012759.1 1558782 1559675 R MG1655 equivalent: b1595; putative DNA-binding transcriptional regulator complement(1558782..1559675) Escherichia coli BW2952 7953450 YP_002926607.1 CDS ynfM NC_012759.1 1559782 1561035 D MG1655 equivalent: b1596; putative transporter 1559782..1561035 Escherichia coli BW2952 7954758 YP_002926608.1 CDS asr NC_012759.1 1561459 1561767 D required for growth and survival under moderately acid conditions; acid shock protein 1561459..1561767 Escherichia coli BW2952 7955686 YP_002926609.1 CDS ydgU NC_012759.1 1561860 1561943 D MG1655 equivalent: b4601; membrane protein 1561860..1561943 Escherichia coli BW2952 7952408 YP_002926610.1 CDS ydgD NC_012759.1 1562043 1562864 D MG1655 equivalent: b1598; putative peptidase 1562043..1562864 Escherichia coli BW2952 7953980 YP_002926611.1 CDS mdtI NC_012759.1 1562903 1563232 R with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI complement(1562903..1563232) Escherichia coli BW2952 7955280 YP_002926612.1 CDS mdtJ NC_012759.1 1563219 1563584 R with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtJ complement(1563219..1563584) Escherichia coli BW2952 7954308 YP_002926613.1 CDS tqsA NC_012759.1 1563996 1565030 D transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; putative transport protein 1563996..1565030 Escherichia coli BW2952 7954309 YP_002926614.1 CDS pntB NC_012759.1 1565055 1566443 R catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase complement(1565055..1566443) Escherichia coli BW2952 7955042 YP_002926615.1 CDS pntA NC_012759.1 1566454 1567986 R forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha complement(1566454..1567986) Escherichia coli BW2952 7955836 YP_002926616.1 CDS ydgH NC_012759.1 1568510 1569454 D MG1655 equivalent: b1604; hypothetical protein 1568510..1569454 Escherichia coli BW2952 7955835 YP_002926617.1 CDS ydgI NC_012759.1 1569640 1571022 D MG1655 equivalent: b1605; putative arginine/ornithine antiporter transporter 1569640..1571022 Escherichia coli BW2952 7955475 YP_002926618.1 CDS folM NC_012759.1 1571059 1571781 D MG1655 equivalent: b1606; short chain dehydrogenase 1571059..1571781 Escherichia coli BW2952 7954658 YP_002926619.1 CDS ydgC NC_012759.1 1571778 1572113 R MG1655 equivalent: b1607; conserved inner membrane protein associated with alginate biosynthesis complement(1571778..1572113) Escherichia coli BW2952 7953252 YP_002926620.1 CDS rstA NC_012759.1 1572242 1572961 D response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 1572242..1572961 Escherichia coli BW2952 7952741 YP_002926621.1 CDS rstB NC_012759.1 1572965 1574266 D MG1655 equivalent: b1609; sensor protein RstB 1572965..1574266 Escherichia coli BW2952 7953361 YP_002926622.1 CDS tus NC_012759.1 1574342 1575271 D binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 1574342..1575271 Escherichia coli BW2952 7956025 YP_002926623.1 CDS fumC NC_012759.1 1575268 1576671 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(1575268..1576671) Escherichia coli BW2952 7953994 YP_002926624.1 CDS fumA NC_012759.1 1576814 1578460 R MG1655 equivalent: b1612; fumarate hydratase (fumarase A), aerobic Class I complement(1576814..1578460) Escherichia coli BW2952 7953643 YP_002926625.1 CDS manA NC_012759.1 1578659 1579834 D MG1655 equivalent: b1613; mannose-6-phosphate isomerase 1578659..1579834 Escherichia coli BW2952 7953642 YP_002926626.1 CDS ydgA NC_012759.1 1579935 1581443 D MG1655 equivalent: b1614; hypothetical protein 1579935..1581443 Escherichia coli BW2952 7954215 YP_002926627.1 CDS uidC NC_012759.1 1581669 1582934 R MG1655 equivalent: b1615; putative outer membrane porin protein complement(1581669..1582934) Escherichia coli BW2952 7952971 YP_002926628.1 CDS uidA NC_012759.1 1584343 1586154 R MG1655 equivalent: b1617; beta-D-glucuronidase complement(1584343..1586154) Escherichia coli BW2952 7955208 YP_002926629.1 CDS uidR NC_012759.1 1586545 1587135 R MG1655 equivalent: b1618; DNA-binding transcriptional repressor complement(1586545..1587135) Escherichia coli BW2952 7952547 YP_002926630.1 CDS hdhA NC_012759.1 1587356 1588123 R Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase complement(1587356..1588123) Escherichia coli BW2952 7953451 YP_002926631.1 CDS malI NC_012759.1 1588235 1589263 R regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI complement(1588235..1589263) Escherichia coli BW2952 7952384 YP_002926632.1 CDS malX NC_012759.1 1589438 1591030 D phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; bifunctional PTS system maltose and glucose-specific transporter subunits IICB 1589438..1591030 Escherichia coli BW2952 7953452 YP_002926633.1 CDS malY NC_012759.1 1591040 1592212 D MG1655 equivalent: b1622; bifunctional beta-cystathionase, PLP-dependent/ regulator of maltose regulon 1591040..1592212 Escherichia coli BW2952 7953696 YP_002926634.1 CDS add NC_012759.1 1592316 1593317 D catalyzes the formation of inosine from adenosine; adenosine deaminase 1592316..1593317 Escherichia coli BW2952 7952562 YP_002926635.1 CDS ydgJ NC_012759.1 1593351 1594391 R MG1655 equivalent: b1624; putative oxidoreductase complement(1593351..1594391) Escherichia coli BW2952 7952421 YP_002926636.1 CDS blr NC_012759.1 1594634 1594759 D MG1655 equivalent: b4409; beta-lactam resistance membrane protein 1594634..1594759 Escherichia coli BW2952 7955225 YP_002926637.1 CDS cnu NC_012759.1 1595032 1595247 D YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 1595032..1595247 Escherichia coli BW2952 7952551 YP_002926638.1 CDS ydgK NC_012759.1 1595333 1595773 D MG1655 equivalent: b1626; hypothetical protein 1595333..1595773 Escherichia coli BW2952 7955560 YP_002926639.1 CDS rsxA NC_012759.1 1595850 1596431 D MG1655 equivalent: b1627; Na(+)-translocating NADH-quinone reductase subunit E 1595850..1596431 Escherichia coli BW2952 7952708 YP_002926640.1 CDS rsxB NC_012759.1 1596431 1597009 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1596431..1597009 Escherichia coli BW2952 7955079 YP_002926641.1 CDS rsxC NC_012759.1 1597002 1599224 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1597002..1599224 Escherichia coli BW2952 7955089 YP_002926642.1 CDS rnfD NC_012759.1 1599225 1600283 D RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1599225..1600283 Escherichia coli BW2952 7953707 YP_002926643.1 CDS rsxG NC_012759.1 1600287 1600907 D part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1600287..1600907 Escherichia coli BW2952 7954983 YP_002926644.1 CDS rsxE NC_012759.1 1600911 1601606 D in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE 1600911..1601606 Escherichia coli BW2952 7955232 YP_002926645.1 CDS nth NC_012759.1 1601606 1602241 D DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 1601606..1602241 Escherichia coli BW2952 7954982 YP_002926646.1 CDS tppB NC_012759.1 1602852 1604354 D mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; putative tripeptide transporter permease 1602852..1604354 Escherichia coli BW2952 7953305 YP_002926647.1 CDS gst NC_012759.1 1604460 1605065 D MG1655 equivalent: b1635; glutathionine S-transferase 1604460..1605065 Escherichia coli BW2952 7955687 YP_002926648.1 CDS pdxY NC_012759.1 1605109 1605972 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase complement(1605109..1605972) Escherichia coli BW2952 7953841 YP_002926649.1 CDS tyrS NC_012759.1 1606031 1607305 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(1606031..1607305) Escherichia coli BW2952 7955838 YP_002926650.1 CDS pdxH NC_012759.1 1607434 1608090 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase complement(1607434..1608090) Escherichia coli BW2952 7956224 YP_002926651.1 CDS ydhA NC_012759.1 1608149 1608478 R MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor complement(1608149..1608478) Escherichia coli BW2952 7955840 YP_002926652.1 CDS anmK NC_012759.1 1608576 1609685 R catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase complement(1608576..1609685) Escherichia coli BW2952 7955108 YP_002926653.1 CDS slyB NC_012759.1 1609959 1610426 D MG1655 equivalent: b1641; outer membrane lipoprotein 1609959..1610426 Escherichia coli BW2952 7952803 YP_002926654.1 CDS slyA NC_012759.1 1610473 1610907 R Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA complement(1610473..1610907) Escherichia coli BW2952 7954438 YP_002926655.1 CDS ydhI NC_012759.1 1611108 1611344 D MG1655 equivalent: b1643; putative inner membrane protein 1611108..1611344 Escherichia coli BW2952 7953365 YP_002926656.1 CDS ydhJ NC_012759.1 1611347 1612204 D MG1655 equivalent: b1644; UDP pyrophosphate phosphatase 1611347..1612204 Escherichia coli BW2952 7955043 YP_002926657.1 CDS ydhK NC_012759.1 1612204 1614216 D MG1655 equivalent: b1645; hypothetical protein 1612204..1614216 Escherichia coli BW2952 7956250 YP_002926658.1 CDS sodC NC_012759.1 1614217 1614738 R SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase complement(1614217..1614738) Escherichia coli BW2952 7952709 YP_002926659.1 CDS ydhF NC_012759.1 1614819 1615715 R MG1655 equivalent: b1647; putative oxidoreductase complement(1614819..1615715) Escherichia coli BW2952 7956099 YP_002926660.1 CDS ydhL NC_012759.1 1615764 1616003 R MG1655 equivalent: b1648; hypothetical protein complement(1615764..1616003) Escherichia coli BW2952 7955226 YP_002926661.1 CDS ydhM NC_012759.1 1616106 1616705 D MG1655 equivalent: b1649; putative DNA-binding transcriptional regulator 1616106..1616705 Escherichia coli BW2952 7952804 YP_002926662.1 CDS nemA NC_012759.1 1616742 1617839 D FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 1616742..1617839 Escherichia coli BW2952 7954802 YP_002926663.1 CDS gloA NC_012759.1 1617920 1618327 D Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 1617920..1618327 Escherichia coli BW2952 7954372 YP_002926664.1 CDS rnt NC_012759.1 1618430 1619077 D Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 1618430..1619077 Escherichia coli BW2952 7953870 YP_002926665.1 CDS lhr NC_012759.1 1619170 1623786 D similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases; longest known protein in E. coli; putative ATP-dependent helicase Lhr 1619170..1623786 Escherichia coli BW2952 7955963 YP_002926666.1 CDS grxD NC_012759.1 1623837 1624184 R MG1655 equivalent: b1654; hypothetical protein complement(1623837..1624184) Escherichia coli BW2952 7954664 YP_002926667.1 CDS ydhO NC_012759.1 1624518 1625333 D MG1655 equivalent: b1655; putative lipoprotein 1624518..1625333 Escherichia coli BW2952 7952805 YP_002926668.1 CDS sodB NC_012759.1 1625461 1626042 D SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 1625461..1626042 Escherichia coli BW2952 7955116 YP_002926669.1 CDS ydhP NC_012759.1 1626204 1627373 R MG1655 equivalent: b1657; putative transporter complement(1626204..1627373) Escherichia coli BW2952 7956100 YP_002926670.1 CDS ynhF NC_012759.1 1627539 1627628 R MG1655 equivalent: b4602; membrane protein complement(1627539..1627628) Escherichia coli BW2952 7955656 YP_002926671.1 CDS purR NC_012759.1 1627927 1628952 D binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1627927..1628952 Escherichia coli BW2952 7953967 YP_002926672.1 CDS ydhB NC_012759.1 1628949 1629881 R MG1655 equivalent: b1659; putative DNA-binding transcriptional regulator complement(1628949..1629881) Escherichia coli BW2952 7953478 YP_002926673.1 CDS ydhC NC_012759.1 1629994 1631205 D uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 1629994..1631205 Escherichia coli BW2952 7954759 YP_002926674.1 CDS cfa NC_012759.1 1631496 1632644 D catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane-fatty-acyl-phospholipid synthase 1631496..1632644 Escherichia coli BW2952 7955688 YP_002926675.1 CDS ribC NC_012759.1 1632684 1633325 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(1632684..1633325) Escherichia coli BW2952 7953178 YP_002926676.1 CDS mdtK NC_012759.1 1633540 1634913 D NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1633540..1634913 Escherichia coli BW2952 7955954 YP_002926677.1 CDS ydhQ NC_012759.1 1634954 1636210 R MG1655 equivalent: b1664; hypothetical protein complement(1634954..1636210) Escherichia coli BW2952 7954310 YP_002926678.1 CDS ydhR NC_012759.1 1636783 1637088 D MG1655 equivalent: b1667; hypothetical protein 1636783..1637088 Escherichia coli BW2952 7952131 YP_002926679.1 CDS ydhS NC_012759.1 1637214 1638818 D MG1655 equivalent: b1668; hypothetical protein 1637214..1638818 Escherichia coli BW2952 7955476 YP_002926680.1 CDS ydhT NC_012759.1 1638830 1639642 R MG1655 equivalent: b1669; hypothetical protein complement(1638830..1639642) Escherichia coli BW2952 7953078 YP_002926681.1 CDS ydhU NC_012759.1 1639646 1640431 R MG1655 equivalent: b1670; putative cytochrome complement(1639646..1640431) Escherichia coli BW2952 7952807 YP_002926682.1 CDS ydhX NC_012759.1 1640428 1641147 R MG1655 equivalent: b1671; 4Fe-4S ferredoxin complement(1640428..1641147) Escherichia coli BW2952 7954706 YP_002926683.1 CDS ydhW NC_012759.1 1641160 1641807 R MG1655 equivalent: b1672; hypothetical protein complement(1641160..1641807) Escherichia coli BW2952 7954594 YP_002926684.1 CDS ydhV NC_012759.1 1641811 1643913 R MG1655 equivalent: b1673; putative oxidoreductase complement(1641811..1643913) Escherichia coli BW2952 7955364 YP_002926685.1 CDS ydhY NC_012759.1 1643934 1644560 R MG1655 equivalent: b1674; hypothetical protein complement(1643934..1644560) Escherichia coli BW2952 7955227 YP_002926686.1 CDS ydhZ NC_012759.1 1645015 1645224 R MG1655 equivalent: b1675; hypothetical protein complement(1645015..1645224) Escherichia coli BW2952 7954595 YP_002926687.1 CDS pykF NC_012759.1 1645781 1647193 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1645781..1647193 Escherichia coli BW2952 7955365 YP_002926688.1 CDS lpp NC_012759.1 1647504 1647740 D MG1655 equivalent: b1677; murein lipoprotein 1647504..1647740 Escherichia coli BW2952 7955852 YP_002926689.1 CDS ynhG NC_012759.1 1647804 1648808 R MG1655 equivalent: b1678; hypothetical protein complement(1647804..1648808) Escherichia coli BW2952 7954321 YP_002926690.1 CDS sufE NC_012759.1 1648957 1649373 R Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE complement(1648957..1649373) Escherichia coli BW2952 7952808 YP_002926691.1 CDS sufS NC_012759.1 1649386 1650606 R catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase complement(1649386..1650606) Escherichia coli BW2952 7956096 YP_002926692.1 CDS sufD NC_012759.1 1650603 1651874 R with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD complement(1650603..1651874) Escherichia coli BW2952 7956006 YP_002926693.1 CDS sufC NC_012759.1 1651849 1652595 R part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase complement(1651849..1652595) Escherichia coli BW2952 7952659 YP_002926694.1 CDS sufB NC_012759.1 1652605 1654092 R with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB complement(1652605..1654092) Escherichia coli BW2952 7952661 YP_002926695.1 CDS sufA NC_012759.1 1654101 1654469 R functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein complement(1654101..1654469) Escherichia coli BW2952 7952660 YP_002926696.1 CDS ydiH NC_012759.1 1655017 1655286 R MG1655 equivalent: b1685; hypothetical protein complement(1655017..1655286) Escherichia coli BW2952 7952083 YP_002926697.1 CDS ydiI NC_012759.1 1655305 1655715 R MG1655 equivalent: b1686; hypothetical protein complement(1655305..1655715) Escherichia coli BW2952 7955366 YP_002926698.1 CDS ydiJ NC_012759.1 1655712 1658768 R MG1655 equivalent: b1687; putative FAD-linked oxidoreductase complement(1655712..1658768) Escherichia coli BW2952 7952809 YP_002926699.1 CDS ydiK NC_012759.1 1659157 1660269 D YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; putative inner membrane protein 1659157..1660269 Escherichia coli BW2952 7954868 YP_002926700.1 CDS ydiL NC_012759.1 1660698 1661054 D MG1655 equivalent: b1689; hypothetical protein 1660698..1661054 Escherichia coli BW2952 7952179 YP_002926701.1 CDS ydiM NC_012759.1 1661154 1662368 D MG1655 equivalent: b1690; putative transporter 1661154..1662368 Escherichia coli BW2952 7952972 YP_002926702.1 CDS ydiN NC_012759.1 1662589 1663860 D MG1655 equivalent: b1691; putative transporter 1662589..1663860 Escherichia coli BW2952 7955689 YP_002926703.1 CDS ydiB NC_012759.1 1663872 1664738 D YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 1663872..1664738 Escherichia coli BW2952 7955690 YP_002926704.1 CDS aroD NC_012759.1 1664769 1665527 D catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1664769..1665527 Escherichia coli BW2952 7955884 YP_002926705.1 CDS ydiF NC_012759.1 1665670 1667265 D MG1655 equivalent: b1694; fused putative acetyl-CoA:acetoacetyl-CoA transferase: alpha subunit/beta subunit 1665670..1667265 Escherichia coli BW2952 7952295 YP_002926706.1 CDS ydiO NC_012759.1 1667279 1668430 D may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; putative acyl-CoA dehydrogenase 1667279..1668430 Escherichia coli BW2952 7953708 YP_002926707.1 CDS ydiP NC_012759.1 1668473 1669384 R MG1655 equivalent: b1696; putative DNA-binding transcriptional regulator complement(1668473..1669384) Escherichia coli BW2952 7954609 YP_002926708.1 CDS ydiQ NC_012759.1 1669700 1670464 D YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; putative electron transfer flavoprotein YdiQ 1669700..1670464 Escherichia coli BW2952 7954760 YP_002926709.1 CDS ydiR NC_012759.1 1670484 1671422 D May play a role in a redox process; electron transfer flavoprotein subunit YdiR 1670484..1671422 Escherichia coli BW2952 7952973 YP_002926710.1 CDS ydiS NC_012759.1 1671478 1672767 D MG1655 equivalent: b1699; hypothetical protein 1671478..1672767 Escherichia coli BW2952 7954830 YP_002926711.1 CDS ydiT NC_012759.1 1672764 1673057 D MG1655 equivalent: b1700; putative 4Fe-4S ferredoxin-type protein 1672764..1673057 Escherichia coli BW2952 7955242 YP_002926712.1 CDS fadK NC_012759.1 1673114 1674760 D acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids; short chain acyl-CoA synthetase 1673114..1674760 Escherichia coli BW2952 7954593 YP_002926713.1 CDS pps NC_012759.1 1674817 1677195 R catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase complement(1674817..1677195) Escherichia coli BW2952 7956040 YP_002926714.1 CDS ydiA NC_012759.1 1677528 1678361 D MG1655 equivalent: b1703; hypothetical protein 1677528..1678361 Escherichia coli BW2952 7954530 YP_002926715.1 CDS aroH NC_012759.1 1678518 1679564 D tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 1678518..1679564 Escherichia coli BW2952 7952974 YP_002926716.1 CDS ydiE NC_012759.1 1679696 1679887 D MG1655 equivalent: b1705; hypothetical protein 1679696..1679887 Escherichia coli BW2952 7952298 YP_002926717.1 CDS ydiU NC_012759.1 1679891 1681327 R MG1655 equivalent: b1706; hypothetical protein complement(1679891..1681327) Escherichia coli BW2952 7952975 YP_002926718.1 CDS ydiV NC_012759.1 1681390 1682103 R MG1655 equivalent: b1707; hypothetical protein complement(1681390..1682103) Escherichia coli BW2952 7952810 YP_002926719.1 CDS nlpC NC_012759.1 1682350 1682814 R MG1655 equivalent: b1708; putative lipoprotein complement(1682350..1682814) Escherichia coli BW2952 7952811 YP_002926720.1 CDS btuD NC_012759.1 1682892 1683641 R ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase complement(1682892..1683641) Escherichia coli BW2952 7955109 YP_002926721.1 CDS btuE NC_012759.1 1683641 1684192 R similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; putative glutathione peroxidase complement(1683641..1684192) Escherichia coli BW2952 7956271 YP_002926722.1 CDS btuC NC_012759.1 1684255 1685235 R with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease complement(1684255..1685235) Escherichia coli BW2952 7954925 YP_002926723.1 CDS ihfA NC_012759.1 1685336 1685635 R This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha complement(1685336..1685635) Escherichia coli BW2952 7956272 YP_002926724.1 CDS pheT NC_012759.1 1685640 1688027 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(1685640..1688027) Escherichia coli BW2952 7954010 YP_002926725.1 CDS pheS NC_012759.1 1688042 1689025 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha complement(1688042..1689025) Escherichia coli BW2952 7954510 YP_002926727.1 CDS rplT NC_012759.1 1689476 1689832 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(1689476..1689832) Escherichia coli BW2952 7954511 YP_002926728.1 CDS rpmI NC_012759.1 1689885 1690082 R MG1655 equivalent: b1717; 50S ribosomal protein L35 complement(1689885..1690082) Escherichia coli BW2952 7952348 YP_002926729.1 CDS infC NC_012759.1 1690179 1690721 R IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 complement(1690179..1690721) Escherichia coli BW2952 7952363 YP_002926730.1 CDS thrS NC_012759.1 1690725 1692653 R catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase complement(1690725..1692653) Escherichia coli BW2952 7955789 YP_002926731.1 CDS yniD NC_012759.1 1695248 1695355 D MG1655 equivalent: b4535; hypothetical protein 1695248..1695355 Escherichia coli BW2952 7956147 YP_002926732.1 CDS ydiY NC_012759.1 1695408 1696166 R MG1655 equivalent: b1722; hypothetical protein complement(1695408..1696166) Escherichia coli BW2952 7955530 YP_002926733.1 CDS pfkB NC_012759.1 1696453 1697382 D MG1655 equivalent: b1723; 6-phosphofructokinase 1696453..1697382 Escherichia coli BW2952 7952812 YP_002926734.1 CDS ydiZ NC_012759.1 1697483 1697773 D MG1655 equivalent: b1724; hypothetical protein 1697483..1697773 Escherichia coli BW2952 7952378 YP_002926735.1 CDS yniA NC_012759.1 1697879 1698739 D MG1655 equivalent: b1725; putative phosphotransferase/kinase 1697879..1698739 Escherichia coli BW2952 7955477 YP_002926736.1 CDS yniB NC_012759.1 1698780 1699316 R MG1655 equivalent: b1726; putative inner membrane protein complement(1698780..1699316) Escherichia coli BW2952 7955321 YP_002926737.1 CDS yniC NC_012759.1 1699463 1700131 D YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 1699463..1700131 Escherichia coli BW2952 7954996 YP_002926738.1 CDS ydjM NC_012759.1 1700282 1700884 D MG1655 equivalent: b1728; hypothetical protein 1700282..1700884 Escherichia coli BW2952 7954966 YP_002926739.1 CDS ydjN NC_012759.1 1701017 1702408 D MG1655 equivalent: b1729; putative transporter 1701017..1702408 Escherichia coli BW2952 7955076 YP_002926740.1 CDS ydjO NC_012759.1 1702412 1703227 R MG1655 equivalent: b1730; hypothetical protein complement(1702412..1703227) Escherichia coli BW2952 7955691 YP_002926741.1 CDS cedA NC_012759.1 1703504 1703746 R MG1655 equivalent: b1731; cell division modulator complement(1703504..1703746) Escherichia coli BW2952 7955367 YP_002926742.1 CDS katE NC_012759.1 1703950 1706211 D Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 1703950..1706211 Escherichia coli BW2952 7952615 YP_002926743.1 CDS chbG NC_012759.1 1706469 1707218 R MG1655 equivalent: b1733; hypothetical protein complement(1706469..1707218) Escherichia coli BW2952 7953958 YP_002926744.1 CDS chbF NC_012759.1 1707231 1708583 R MG1655 equivalent: b1734; cryptic phospho-beta-glucosidase, NAD(P)-binding complement(1707231..1708583) Escherichia coli BW2952 7952813 YP_002926745.1 CDS chbR NC_012759.1 1708688 1709530 R represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR complement(1708688..1709530) Escherichia coli BW2952 7953172 YP_002926746.1 CDS chbA NC_012759.1 1709538 1709888 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA complement(1709538..1709888) Escherichia coli BW2952 7953406 YP_002926747.1 CDS chbC NC_012759.1 1709939 1711297 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC complement(1709939..1711297) Escherichia coli BW2952 7954327 YP_002926748.1 CDS chbB NC_012759.1 1711382 1711702 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB complement(1711382..1711702) Escherichia coli BW2952 7954329 YP_002926749.1 CDS osmE NC_012759.1 1712001 1712339 R osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE complement(1712001..1712339) Escherichia coli BW2952 7954328 YP_002926750.1 CDS nadE NC_012759.1 1712541 1713368 D catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1712541..1713368 Escherichia coli BW2952 7953366 YP_002926751.1 CDS cho NC_012759.1 1713598 1714485 D 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 1713598..1714485 Escherichia coli BW2952 7954349 YP_002926752.1 CDS ves NC_012759.1 1714445 1715020 R MG1655 equivalent: b1742; hypothetical protein complement(1714445..1715020) Escherichia coli BW2952 7953518 YP_002926753.1 CDS spy NC_012759.1 1715223 1715708 R periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; hypothetical protein complement(1715223..1715708) Escherichia coli BW2952 7952814 YP_002926754.1 CDS astE NC_012759.1 1716038 1717006 R catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase complement(1716038..1717006) Escherichia coli BW2952 7953530 YP_002926755.1 CDS astB NC_012759.1 1716999 1718342 R catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase complement(1716999..1718342) Escherichia coli BW2952 7956084 YP_002926756.1 CDS astD NC_012759.1 1718339 1719817 R a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase complement(1718339..1719817) Escherichia coli BW2952 7956081 YP_002926757.1 CDS astA NC_012759.1 1719814 1720848 R MG1655 equivalent: b1747; arginine succinyltransferase complement(1719814..1720848) Escherichia coli BW2952 7956085 YP_002926758.1 CDS astC NC_012759.1 1720845 1722065 R catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase complement(1720845..1722065) Escherichia coli BW2952 7952493 YP_002926759.1 CDS xthA NC_012759.1 1722511 1723317 D removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1722511..1723317 Escherichia coli BW2952 7956086 YP_002926760.1 CDS ydjX NC_012759.1 1723484 1724194 D MG1655 equivalent: b1750; putative inner membrane protein 1723484..1724194 Escherichia coli BW2952 7953540 YP_002926761.1 CDS ydjY NC_012759.1 1724199 1724876 D MG1655 equivalent: b1751; hypothetical protein 1724199..1724876 Escherichia coli BW2952 7955045 YP_002926762.1 CDS ydjZ NC_012759.1 1724891 1725598 D MG1655 equivalent: b1752; hypothetical protein 1724891..1725598 Escherichia coli BW2952 7955478 YP_002926763.1 CDS ynjA NC_012759.1 1725598 1726146 D MG1655 equivalent: b1753; hypothetical protein 1725598..1726146 Escherichia coli BW2952 7952710 YP_002926764.1 CDS ynjB NC_012759.1 1726156 1727322 D MG1655 equivalent: b1754; putative ABC transporter solute-binding protein 1726156..1727322 Escherichia coli BW2952 7952976 YP_002926765.1 CDS ynjC NC_012759.1 1727295 1728830 D MG1655 equivalent: b1755; fused transporter subunits of ABC superfamily: membrane components 1727295..1728830 Escherichia coli BW2952 7952977 YP_002926766.1 CDS ynjD NC_012759.1 1728830 1729483 D MG1655 equivalent: b1756; putative transporter subunit: ATP-binding component of ABC superfamily 1728830..1729483 Escherichia coli BW2952 7953748 YP_002926767.1 CDS ynjE NC_012759.1 1729550 1730857 D MG1655 equivalent: b1757; putative thiosulfate sulfur transferase 1729550..1730857 Escherichia coli BW2952 7955723 YP_002926768.1 CDS ynjF NC_012759.1 1730866 1731486 R MG1655 equivalent: b1758; putative phosphatidyl transferase, inner membrane protein complement(1730866..1731486) Escherichia coli BW2952 7955623 YP_002926769.1 CDS nudG NC_012759.1 1731573 1731980 D MG1655 equivalent: b1759; pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 1731573..1731980 Escherichia coli BW2952 7955314 YP_002926770.1 CDS ynjH NC_012759.1 1731946 1732218 R MG1655 equivalent: b1760; hypothetical protein complement(1731946..1732218) Escherichia coli BW2952 7955842 YP_002926771.1 CDS gdhA NC_012759.1 1732454 1733797 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1732454..1733797 Escherichia coli BW2952 7955368 YP_002926772.1 CDS ynjI NC_012759.1 1733914 1734954 R MG1655 equivalent: b1762; hypothetical protein complement(1733914..1734954) Escherichia coli BW2952 7953820 YP_002926773.1 CDS topB NC_012759.1 1735082 1737043 R decatenates replicating daughter chromosomes; DNA topoisomerase III complement(1735082..1737043) Escherichia coli BW2952 7954997 YP_002926774.1 CDS selD NC_012759.1 1737048 1738091 R catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase complement(1737048..1738091) Escherichia coli BW2952 7953334 YP_002926775.1 CDS ydjA NC_012759.1 1738208 1738759 R MG1655 equivalent: b1765; hypothetical protein complement(1738208..1738759) Escherichia coli BW2952 7956009 YP_002926776.1 CDS sppA NC_012759.1 1738920 1740776 D SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 1738920..1740776 Escherichia coli BW2952 7955228 YP_002926777.1 CDS ansA NC_012759.1 1740943 1741959 D converts asparagine to aspartate and ammonia; asparaginase 1740943..1741959 Escherichia coli BW2952 7955778 YP_002926778.1 CDS pncA NC_012759.1 1741970 1742611 D catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 1741970..1742611 Escherichia coli BW2952 7953202 YP_002926779.1 CDS ydjE NC_012759.1 1742704 1744062 R MG1655 equivalent: b1769; putative transporter complement(1742704..1744062) Escherichia coli BW2952 7954382 YP_002926780.1 CDS ydjF NC_012759.1 1744179 1744937 R MG1655 equivalent: b1770; putative DNA-binding transcriptional regulator complement(1744179..1744937) Escherichia coli BW2952 7955657 YP_002926781.1 CDS ydjG NC_012759.1 1745074 1746054 R MG1655 equivalent: b1771; putative oxidoreductase complement(1745074..1746054) Escherichia coli BW2952 7954761 YP_002926782.1 CDS ydjH NC_012759.1 1746064 1747011 R MG1655 equivalent: b1772; putative kinase complement(1746064..1747011) Escherichia coli BW2952 7955229 YP_002926783.1 CDS ydjI NC_012759.1 1747016 1747852 R MG1655 equivalent: b1773; putative aldolase complement(1747016..1747852) Escherichia coli BW2952 7955092 YP_002926784.1 CDS ydjJ NC_012759.1 1747873 1748916 R MG1655 equivalent: b1774; putative oxidoreductase, Zn-dependent and NAD(P)-binding complement(1747873..1748916) Escherichia coli BW2952 7954629 YP_002926785.1 CDS ydjK NC_012759.1 1748933 1750312 R MG1655 equivalent: b1775; putative transporter complement(1748933..1750312) Escherichia coli BW2952 7955259 YP_002926786.1 CDS ydjL NC_012759.1 1750339 1751415 R MG1655 equivalent: b1776; putative oxidoreductase, Zn-dependent and NAD(P)-binding complement(1750339..1751415) Escherichia coli BW2952 7955658 YP_002926787.1 CDS yeaC NC_012759.1 1751785 1752057 R MG1655 equivalent: b1777; hypothetical protein complement(1751785..1752057) Escherichia coli BW2952 7955260 YP_002926788.1 CDS msrB NC_012759.1 1752099 1752512 R this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B complement(1752099..1752512) Escherichia coli BW2952 7952815 YP_002926789.1 CDS gapA NC_012759.1 1752854 1753849 D MG1655 equivalent: b1779; glyceraldehyde-3-phosphate dehydrogenase 1752854..1753849 Escherichia coli BW2952 7954246 YP_002926790.1 CDS yeaD NC_012759.1 1753933 1754817 D MG1655 equivalent: b1780; hypothetical protein 1753933..1754817 Escherichia coli BW2952 7953842 YP_002926791.1 CDS yeaE NC_012759.1 1754865 1755719 R MG1655 equivalent: b1781; putative oxidoreductase complement(1754865..1755719) Escherichia coli BW2952 7952978 YP_002926792.1 CDS mipA NC_012759.1 1755809 1756555 R MG1655 equivalent: b1782; scaffolding protein for murein synthesizing machinery complement(1755809..1756555) Escherichia coli BW2952 7955230 YP_002926793.1 CDS yeaG NC_012759.1 1756991 1758925 D MG1655 equivalent: b1783; hypothetical protein 1756991..1758925 Escherichia coli BW2952 7956002 YP_002926794.1 CDS yeaH NC_012759.1 1759038 1760321 D MG1655 equivalent: b1784; hypothetical protein 1759038..1760321 Escherichia coli BW2952 7953091 YP_002926795.1 CDS yeaI NC_012759.1 1760468 1761943 D MG1655 equivalent: b1785; putative diguanylate cyclase 1760468..1761943 Escherichia coli BW2952 7952979 YP_002926796.1 CDS yeaJ NC_012759.1 1762124 1763614 D MG1655 equivalent: b1786; putative diguanylate cyclase 1762124..1763614 Escherichia coli BW2952 7954729 YP_002926797.1 CDS yeaK NC_012759.1 1763657 1764160 D MG1655 equivalent: b1787; hypothetical protein 1763657..1764160 Escherichia coli BW2952 7954730 YP_002926798.1 CDS yoaI NC_012759.1 1764161 1764265 R MG1655 equivalent: b1788; hypothetical protein complement(1764161..1764265) Escherichia coli BW2952 7952980 YP_002926799.1 CDS yeaL NC_012759.1 1764435 1764881 D MG1655 equivalent: b1789; hypothetical protein 1764435..1764881 Escherichia coli BW2952 7955369 YP_002926800.1 CDS yeaM NC_012759.1 1764838 1765659 R MG1655 equivalent: b1790; putative DNA-binding transcriptional regulator complement(1764838..1765659) Escherichia coli BW2952 7952711 YP_002926801.1 CDS yeaN NC_012759.1 1765756 1766937 D MG1655 equivalent: b1791; putative transporter 1765756..1766937 Escherichia coli BW2952 7954762 YP_002926802.1 CDS yeaO NC_012759.1 1766992 1767339 D MG1655 equivalent: b1792; hypothetical protein 1766992..1767339 Escherichia coli BW2952 7955692 YP_002926803.1 CDS yoaF NC_012759.1 1767361 1767615 R MG1655 equivalent: b1793; hypothetical protein complement(1767361..1767615) Escherichia coli BW2952 7952981 YP_002926804.1 CDS yeaP NC_012759.1 1767798 1768823 D MG1655 equivalent: b1794; putative diguanylate cyclase 1767798..1768823 Escherichia coli BW2952 7952749 YP_002926805.1 CDS yeaQ NC_012759.1 1769090 1769338 R MG1655 equivalent: b1795; hypothetical protein complement(1769090..1769338) Escherichia coli BW2952 7954731 YP_002926806.1 CDS yoaG NC_012759.1 1769486 1769668 R MG1655 equivalent: b1796; hypothetical protein complement(1769486..1769668) Escherichia coli BW2952 7952672 YP_002926807.1 CDS yeaR NC_012759.1 1769672 1770031 R MG1655 equivalent: b1797; hypothetical protein complement(1769672..1770031) Escherichia coli BW2952 7955370 YP_002926808.1 CDS leuE NC_012759.1 1770204 1770842 R MG1655 equivalent: b1798; leucine export protein LeuE complement(1770204..1770842) Escherichia coli BW2952 7952816 YP_002926809.1 CDS yeaT NC_012759.1 1770969 1771892 R MG1655 equivalent: b1799; putative DNA-binding transcriptional regulator complement(1770969..1771892) Escherichia coli BW2952 7954373 YP_002926810.1 CDS yeaU NC_012759.1 1771995 1773080 D MG1655 equivalent: b1800; putative dehydrogenase 1771995..1773080 Escherichia coli BW2952 7954763 YP_002926811.1 CDS yeaV NC_012759.1 1773271 1774716 D member of the betaine, carnitine, choline transporter (BCCT) family; unknown function; putative transporter 1773271..1774716 Escherichia coli BW2952 7954716 YP_002926812.1 CDS yeaW NC_012759.1 1774748 1775872 D MG1655 equivalent: b1802; putative 2Fe-2S cluster-containing protein 1774748..1775872 Escherichia coli BW2952 7955693 YP_002926813.1 CDS yeaX NC_012759.1 1775928 1776893 D MG1655 equivalent: b1803; putative oxidoreductase 1775928..1776893 Escherichia coli BW2952 7954585 YP_002926814.1 CDS rnd NC_012759.1 1776947 1778074 R MG1655 equivalent: b1804; ribonuclease D complement(1776947..1778074) Escherichia coli BW2952 7955233 YP_002926815.1 CDS fadD NC_012759.1 1778144 1779829 R Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(1778144..1779829) Escherichia coli BW2952 7955956 YP_002926816.1 CDS yeaY NC_012759.1 1780034 1780615 R MG1655 equivalent: b1806; putative lipoprotein complement(1780034..1780615) Escherichia coli BW2952 7952416 YP_002926817.1 CDS yeaZ NC_012759.1 1780655 1781350 R MG1655 equivalent: b1807; putative peptidase complement(1780655..1781350) Escherichia coli BW2952 7955110 YP_002926818.1 CDS yoaA NC_012759.1 1781408 1783318 R MG1655 equivalent: b1808; hypothetical protein complement(1781408..1783318) Escherichia coli BW2952 7955272 YP_002926819.1 CDS yoaB NC_012759.1 1783450 1783794 D MG1655 equivalent: b1809; hypothetical protein 1783450..1783794 Escherichia coli BW2952 7953084 YP_002926820.1 CDS yoaC NC_012759.1 1784156 1784515 D MG1655 equivalent: b1810; hypothetical protein 1784156..1784515 Escherichia coli BW2952 7952982 YP_002926821.1 CDS yoaH NC_012759.1 1784635 1784814 R MG1655 equivalent: b1811; hypothetical protein complement(1784635..1784814) Escherichia coli BW2952 7955479 YP_002926822.1 CDS pabB NC_012759.1 1784888 1786249 D MG1655 equivalent: b1812; aminodeoxychorismate synthase subunit I 1784888..1786249 Escherichia coli BW2952 7952817 YP_002926823.1 CDS nudL NC_012759.1 1786253 1786831 D MG1655 equivalent: b1813; hypothetical protein 1786253..1786831 Escherichia coli BW2952 7952465 YP_002926824.1 CDS sdaA NC_012759.1 1787015 1788379 D MG1655 equivalent: b1814; L-serine deaminase I 1787015..1788379 Escherichia coli BW2952 7955190 YP_002926825.1 CDS yoaD NC_012759.1 1788510 1790108 D MG1655 equivalent: b1815; putative phosphodiesterase 1788510..1790108 Escherichia coli BW2952 7954170 YP_002926826.1 CDS yoaE NC_012759.1 1790112 1791668 R MG1655 equivalent: b1816; hypothetical protein complement(1790112..1791668) Escherichia coli BW2952 7955315 YP_002926827.1 CDS manX NC_012759.1 1792131 1793102 D MG1655 equivalent: b1817; fused mannose-specific PTS enzymes: IIA component/IIB component 1792131..1793102 Escherichia coli BW2952 7953713 YP_002926828.1 CDS manY NC_012759.1 1793165 1793965 D MG1655 equivalent: b1818; mannose-specific enzyme IIC component of PTS 1793165..1793965 Escherichia coli BW2952 7953699 YP_002926829.1 CDS manZ NC_012759.1 1793969 1794829 D hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 1793969..1794829 Escherichia coli BW2952 7954216 YP_002926830.1 CDS yobD NC_012759.1 1794884 1795342 D MG1655 equivalent: b1820; hypothetical protein 1794884..1795342 Escherichia coli BW2952 7954217 YP_002926831.1 CDS yebN NC_012759.1 1795771 1796337 D membrane protein YebN; hypothetical protein 1795771..1796337 Escherichia coli BW2952 7952712 YP_002926832.1 CDS rrmA NC_012759.1 1796334 1797143 R methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase A complement(1796334..1797143) Escherichia coli BW2952 7952713 YP_002926833.1 CDS cspC NC_012759.1 1797309 1797518 R MG1655 equivalent: b1823; cold shock-like protein CspC complement(1797309..1797518) Escherichia coli BW2952 7952244 YP_002926834.1 CDS yobF NC_012759.1 1797531 1797674 R MG1655 equivalent: b1824; hypothetical protein complement(1797531..1797674) Escherichia coli BW2952 7956070 YP_002926835.1 CDS yebO NC_012759.1 1798344 1798631 R MG1655 equivalent: b1825; hypothetical protein complement(1798344..1798631) Escherichia coli BW2952 7955371 YP_002926836.1 CDS mgrB NC_012759.1 1798706 1798849 R MG1655 equivalent: b1826; hypothetical protein complement(1798706..1798849) Escherichia coli BW2952 7955372 YP_002926837.1 CDS yobH NC_012759.1 1799008 1799247 D MG1655 equivalent: b4536; hypothetical protein 1799008..1799247 Escherichia coli BW2952 7955373 YP_002926838.1 CDS kdgR NC_012759.1 1799391 1800182 R MG1655 equivalent: b1827; putative DNA-binding transcriptional regulator complement(1799391..1800182) Escherichia coli BW2952 7955531 YP_002926839.1 CDS yebQ NC_012759.1 1800359 1801732 D MG1655 equivalent: b1828; putative transporter 1800359..1801732 Escherichia coli BW2952 7954764 YP_002926840.1 CDS htpX NC_012759.1 1801778 1802659 R putative metalloprotease; heat shock protein HtpX complement(1801778..1802659) Escherichia coli BW2952 7955694 YP_002926841.1 CDS prc NC_012759.1 1802851 1804899 R Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease complement(1802851..1804899) Escherichia coli BW2952 7954836 YP_002926842.1 CDS proQ NC_012759.1 1804919 1805617 R affects solute and DNA transport through an unknown mechanism; putative solute/DNA competence effector complement(1804919..1805617) Escherichia coli BW2952 7952607 YP_002926843.1 CDS yebR NC_012759.1 1805714 1806211 R MG1655 equivalent: b1832; free methionine-(R)-sulfoxide reductase complement(1805714..1806211) Escherichia coli BW2952 7955601 YP_002926844.1 CDS yebS NC_012759.1 1806341 1807624 D MG1655 equivalent: b1833; hypothetical protein 1806341..1807624 Escherichia coli BW2952 7953632 YP_002926845.1 CDS yebT NC_012759.1 1807593 1810226 D MG1655 equivalent: b1834; hypothetical protein 1807593..1810226 Escherichia coli BW2952 7952714 YP_002926846.1 CDS yebU NC_012759.1 1810306 1811745 D in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 1810306..1811745 Escherichia coli BW2952 7952983 YP_002926847.1 CDS yebV NC_012759.1 1811863 1812099 D MG1655 equivalent: b1836; hypothetical protein 1811863..1812099 Escherichia coli BW2952 7955158 YP_002926848.1 CDS yebW NC_012759.1 1812204 1812395 D MG1655 equivalent: b1837; hypothetical protein 1812204..1812395 Escherichia coli BW2952 7955480 YP_002926849.1 CDS pphA NC_012759.1 1812396 1813052 R Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 complement(1812396..1813052) Escherichia coli BW2952 7955481 YP_002926850.1 CDS yebY NC_012759.1 1813448 1813789 R MG1655 equivalent: b1839; hypothetical protein complement(1813448..1813789) Escherichia coli BW2952 7952084 YP_002926851.1 CDS yebZ NC_012759.1 1813802 1814674 R MG1655 equivalent: b1840; putative inner membrane protein complement(1813802..1814674) Escherichia coli BW2952 7955374 YP_002926852.1 CDS yobA NC_012759.1 1814678 1815052 R MG1655 equivalent: b1841; hypothetical protein complement(1814678..1815052) Escherichia coli BW2952 7954998 YP_002926853.1 CDS holE NC_012759.1 1815191 1815421 D MG1655 equivalent: b1842; DNA polymerase III subunit theta 1815191..1815421 Escherichia coli BW2952 7952818 YP_002926854.1 CDS yobB NC_012759.1 1815523 1816179 D MG1655 equivalent: b1843; hypothetical protein 1815523..1816179 Escherichia coli BW2952 7953325 YP_002926855.1 CDS exoX NC_012759.1 1816203 1816865 D 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 1816203..1816865 Escherichia coli BW2952 7952984 YP_002926856.1 CDS ptrB NC_012759.1 1816862 1818922 R PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 complement(1816862..1818922) Escherichia coli BW2952 7953304 YP_002926857.1 CDS yebE NC_012759.1 1819131 1819790 R MG1655 equivalent: b1846; hypothetical protein complement(1819131..1819790) Escherichia coli BW2952 7955775 YP_002926858.1 CDS yebF NC_012759.1 1820117 1820473 R secreted protein; unknown function; hypothetical protein complement(1820117..1820473) Escherichia coli BW2952 7952819 YP_002926859.1 CDS yebG NC_012759.1 1820540 1820830 R MG1655 equivalent: b1848; DNA damage-inducible protein YebG complement(1820540..1820830) Escherichia coli BW2952 7955375 YP_002926860.1 CDS purT NC_012759.1 1820964 1822142 D non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 1820964..1822142 Escherichia coli BW2952 7953075 YP_002926861.1 CDS eda NC_012759.1 1822198 1822839 R catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(1822198..1822839) Escherichia coli BW2952 7954552 YP_002926862.1 CDS edd NC_012759.1 1822876 1824687 R catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase complement(1822876..1824687) Escherichia coli BW2952 7954316 YP_002926863.1 CDS zwf NC_012759.1 1824922 1826397 R catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(1824922..1826397) Escherichia coli BW2952 7952379 YP_002926864.1 CDS yebK NC_012759.1 1826735 1827604 D Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 1826735..1827604 Escherichia coli BW2952 7953809 YP_002926865.1 CDS pykA NC_012759.1 1827732 1829174 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1827732..1829174 Escherichia coli BW2952 7954803 YP_002926866.1 CDS lpxM NC_012759.1 1829305 1830276 R Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase complement(1829305..1830276) Escherichia coli BW2952 7955853 YP_002926867.1 CDS yebA NC_012759.1 1830396 1831718 R MG1655 equivalent: b1856; hypothetical protein complement(1830396..1831718) Escherichia coli BW2952 7954325 YP_002926868.1 CDS znuA NC_012759.1 1831734 1832666 R involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein complement(1831734..1832666) Escherichia coli BW2952 7955273 YP_002926869.1 CDS znuC NC_012759.1 1832745 1833500 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 1832745..1833500 Escherichia coli BW2952 7956288 YP_002926870.1 CDS znuB NC_012759.1 1833497 1834282 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane protein 1833497..1834282 Escherichia coli BW2952 7956286 YP_002926871.1 CDS ruvB NC_012759.1 1834429 1835439 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(1834429..1835439) Escherichia coli BW2952 7956287 YP_002926872.1 CDS ruvA NC_012759.1 1835448 1836059 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(1835448..1836059) Escherichia coli BW2952 7952532 YP_002926873.1 CDS yebB NC_012759.1 1836334 1836936 D MG1655 equivalent: b1862; hypothetical protein 1836334..1836936 Escherichia coli BW2952 7952658 YP_002926874.1 CDS ruvC NC_012759.1 1836938 1837459 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(1836938..1837459) Escherichia coli BW2952 7955482 YP_002926875.1 CDS yebC NC_012759.1 1837494 1838234 R MG1655 equivalent: b1864; hypothetical protein complement(1837494..1838234) Escherichia coli BW2952 7952657 YP_002926876.1 CDS ntpA NC_012759.1 1838263 1838715 R converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase complement(1838263..1838715) Escherichia coli BW2952 7952820 YP_002926877.1 CDS aspS NC_012759.1 1838833 1840605 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(1838833..1840605) Escherichia coli BW2952 7953228 YP_002926878.1 CDS yecD NC_012759.1 1840915 1841481 D MG1655 equivalent: b1867; hypothetical protein 1840915..1841481 Escherichia coli BW2952 7952517 YP_002926879.1 CDS yecE NC_012759.1 1841478 1842296 D MG1655 equivalent: b1868; hypothetical protein 1841478..1842296 Escherichia coli BW2952 7954967 YP_002926880.1 CDS yecN NC_012759.1 1842349 1842744 D MG1655 equivalent: b1869; putative inner membrane protein 1842349..1842744 Escherichia coli BW2952 7952985 YP_002926881.1 CDS cmoA NC_012759.1 1842785 1843528 D MG1655 equivalent: b1870; putative methyltransferase 1842785..1843528 Escherichia coli BW2952 7955046 YP_002926882.1 CDS cmoB NC_012759.1 1843525 1844496 D MG1655 equivalent: b1871; putative S-adenosyl-L-methionine-dependent methyltransferase 1843525..1844496 Escherichia coli BW2952 7955159 YP_002926883.1 CDS torZ NC_012759.1 1844661 1847090 R MG1655 equivalent: b1872; trimethylamine N-oxide reductase system III, catalytic subunit complement(1844661..1847090) Escherichia coli BW2952 7955580 YP_002926884.1 CDS torY NC_012759.1 1847115 1848215 R MG1655 equivalent: b1873; TMAO reductase III (TorYZ), cytochrome c-type subunit complement(1847115..1848215) Escherichia coli BW2952 7956192 YP_002926885.1 CDS cutC NC_012759.1 1848603 1849349 R MG1655 equivalent: b1874; copper homeostasis protein CutC complement(1848603..1849349) Escherichia coli BW2952 7956152 YP_002926886.1 CDS yecM NC_012759.1 1849363 1849929 R MG1655 equivalent: b1875; hypothetical protein complement(1849363..1849929) Escherichia coli BW2952 7953096 YP_002926887.1 CDS argS NC_012759.1 1850145 1851878 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1850145..1851878 Escherichia coli BW2952 7955146 YP_002926888.1 CDS yecT NC_012759.1 1852055 1852543 D MG1655 equivalent: b1877; hypothetical protein 1852055..1852543 Escherichia coli BW2952 7952503 YP_002926889.1 CDS flhE NC_012759.1 1852663 1853055 R MG1655 equivalent: b1878; hypothetical protein complement(1852663..1853055) Escherichia coli BW2952 7955483 YP_002926890.1 CDS flhA NC_012759.1 1853055 1855133 R membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA complement(1853055..1855133) Escherichia coli BW2952 7952821 YP_002926891.1 CDS flhB NC_012759.1 1855126 1856274 R membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB complement(1855126..1856274) Escherichia coli BW2952 7954904 YP_002926892.1 CDS cheZ NC_012759.1 1856476 1857120 R cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ complement(1856476..1857120) Escherichia coli BW2952 7954905 YP_002926893.1 CDS cheY NC_012759.1 1857131 1857520 R chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY complement(1857131..1857520) Escherichia coli BW2952 7952632 YP_002926894.1 CDS cheB NC_012759.1 1857535 1858584 R regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase complement(1857535..1858584) Escherichia coli BW2952 7952631 YP_002926895.1 CDS cheR NC_012759.1 1858587 1859447 R methylates the MCP; chemotaxis methyltransferase CheR complement(1858587..1859447) Escherichia coli BW2952 7953662 YP_002926896.1 CDS tap NC_012759.1 1859466 1861067 R mediates taxis toward dipeptides; methyl-accepting protein IV complement(1859466..1861067) Escherichia coli BW2952 7952633 YP_002926897.1 CDS tar NC_012759.1 1861113 1862774 R MG1655 equivalent: b1886; methyl-accepting chemotaxis protein II complement(1861113..1862774) Escherichia coli BW2952 7954251 YP_002926898.1 CDS cheW NC_012759.1 1862919 1863422 R MG1655 equivalent: b1887; purine-binding chemotaxis protein complement(1862919..1863422) Escherichia coli BW2952 7954249 YP_002926899.1 CDS cheA NC_012759.1 1863443 1865407 R chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA complement(1863443..1865407) Escherichia coli BW2952 7955824 YP_002926900.1 CDS motB NC_012759.1 1865412 1866338 R with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB complement(1865412..1866338) Escherichia coli BW2952 7953661 YP_002926901.1 CDS motA NC_012759.1 1866335 1867222 R With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA complement(1866335..1867222) Escherichia coli BW2952 7955808 YP_002926902.1 CDS flhC NC_012759.1 1867349 1867927 R With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC complement(1867349..1867927) Escherichia coli BW2952 7955816 YP_002926903.1 CDS BWG_1707 NC_012759.1 1868725 1869741 R Transposase insH for insertion sequence element IS5 complement(1868725..1869741) Escherichia coli BW2952 7952208 YP_002926904.1 CDS uspC NC_012759.1 1870260 1870688 D ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 1870260..1870688 Escherichia coli BW2952 7956185 YP_002926905.1 CDS otsA NC_012759.1 1870695 1872119 R MG1655 equivalent: b1896; trehalose-6-phosphate synthase complement(1870695..1872119) Escherichia coli BW2952 7956254 YP_002926906.1 CDS otsB NC_012759.1 1872094 1872894 R biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase complement(1872094..1872894) Escherichia coli BW2952 7956189 YP_002926907.1 CDS araH NC_012759.1 1873061 1874047 R Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease complement(1873061..1874047) Escherichia coli BW2952 7956188 YP_002926908.1 CDS araG NC_012759.1 1874062 1875576 R Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein complement(1874062..1875576) Escherichia coli BW2952 7953692 YP_002926909.1 CDS araF NC_012759.1 1875646 1876635 R MG1655 equivalent: b1901; L-arabinose transporter subunit complement(1875646..1876635) Escherichia coli BW2952 7953691 YP_002926910.1 CDS ftnB NC_012759.1 1877432 1877935 D MG1655 equivalent: b1902; putative ferritin-like protein 1877432..1877935 Escherichia coli BW2952 7954116 YP_002926911.1 CDS yecJ NC_012759.1 1878014 1878265 R MG1655 equivalent: b4537; hypothetical protein complement(1878014..1878265) Escherichia coli BW2952 7954870 YP_002926912.1 CDS yecR NC_012759.1 1878729 1879052 D MG1655 equivalent: b1904; hypothetical protein 1878729..1879052 Escherichia coli BW2952 7952085 YP_002926913.1 CDS ftnA NC_012759.1 1879223 1879720 D cytoplasmic iron storage protein; ferritin 1879223..1879720 Escherichia coli BW2952 7955484 YP_002926914.1 CDS yecH NC_012759.1 1879758 1879997 R MG1655 equivalent: b1906; hypothetical protein complement(1879758..1879997) Escherichia coli BW2952 7953572 YP_002926915.1 CDS tyrP NC_012759.1 1880188 1881399 D MG1655 equivalent: b1907; tyrosine transporter 1880188..1881399 Escherichia coli BW2952 7955376 YP_002926916.1 CDS yecA NC_012759.1 1881461 1882126 R MG1655 equivalent: b1908; hypothetical protein complement(1881461..1882126) Escherichia coli BW2952 7956223 YP_002926917.1 CDS pgsA NC_012759.1 1882776 1883324 R MG1655 equivalent: b1912; phosphatidylglycerophosphate synthetase complement(1882776..1883324) Escherichia coli BW2952 7952055 YP_002926918.1 CDS uvrC NC_012759.1 1883381 1885213 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(1883381..1885213) Escherichia coli BW2952 7954524 YP_002926919.1 CDS uvrY NC_012759.1 1885210 1885866 R in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator complement(1885210..1885866) Escherichia coli BW2952 7953536 YP_002926920.1 CDS yecF NC_012759.1 1886325 1886549 D MG1655 equivalent: b1915; hypothetical protein 1886325..1886549 Escherichia coli BW2952 7953345 YP_002926921.1 CDS sdiA NC_012759.1 1886617 1887339 R regulates genes involved in cell division; DNA-binding transcriptional activator SdiA complement(1886617..1887339) Escherichia coli BW2952 7955485 YP_002926922.1 CDS yecC NC_012759.1 1887569 1888321 R MG1655 equivalent: b1917; putative amino-acid ABC transporter ATP-binding protein YecC complement(1887569..1888321) Escherichia coli BW2952 7953367 YP_002926923.1 CDS yecS NC_012759.1 1888318 1888986 R MG1655 equivalent: b1918; putative transporter subunit: membrane component of ABC superfamily complement(1888318..1888986) Escherichia coli BW2952 7955717 YP_002926924.1 CDS dcyD NC_012759.1 1889001 1889987 R catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase complement(1889001..1889987) Escherichia coli BW2952 7955728 YP_002926925.1 CDS fliY NC_012759.1 1890092 1890892 R MG1655 equivalent: b1920; cystine transporter subunit complement(1890092..1890892) Escherichia coli BW2952 7953229 YP_002926926.1 CDS fliZ NC_012759.1 1890980 1891531 R expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ complement(1890980..1891531) Escherichia coli BW2952 7953187 YP_002926927.1 CDS fliA NC_012759.1 1891577 1892296 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor complement(1891577..1892296) Escherichia coli BW2952 7955564 YP_002926928.1 CDS fliC NC_012759.1 1892617 1894113 R structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes; flagellin complement(1892617..1894113) Escherichia coli BW2952 7955988 YP_002926929.1 CDS fliD NC_012759.1 1894379 1895785 D involved in flagellin assembly; flagellar capping protein 1894379..1895785 Escherichia coli BW2952 7953595 YP_002926930.1 CDS fliS NC_012759.1 1895810 1896220 D flagellin specific chaperone; flagellar protein FliS 1895810..1896220 Escherichia coli BW2952 7953594 YP_002926931.1 CDS fliT NC_012759.1 1896220 1896585 D binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 1896220..1896585 Escherichia coli BW2952 7953606 YP_002926932.1 CDS amyA NC_012759.1 1896663 1898150 D converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 1896663..1898150 Escherichia coli BW2952 7954688 YP_002926933.1 CDS yedD NC_012759.1 1898184 1898597 R MG1655 equivalent: b1928; hypothetical protein complement(1898184..1898597) Escherichia coli BW2952 7953200 YP_002926934.1 CDS yedE NC_012759.1 1898784 1899989 D MG1655 equivalent: b1929; putative inner membrane protein 1898784..1899989 Escherichia coli BW2952 7955377 YP_002926935.1 CDS yedF NC_012759.1 1899986 1900219 D MG1655 equivalent: b1930; hypothetical protein 1899986..1900219 Escherichia coli BW2952 7955047 YP_002926936.1 CDS yedK NC_012759.1 1900328 1900996 D MG1655 equivalent: b1931; hypothetical protein 1900328..1900996 Escherichia coli BW2952 7952986 YP_002926937.1 CDS yedL NC_012759.1 1901107 1901586 D MG1655 equivalent: b1932; putative acyltransferase 1901107..1901586 Escherichia coli BW2952 7955486 YP_002926938.1 CDS fliE NC_012759.1 1903207 1903521 R forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE complement(1903207..1903521) Escherichia coli BW2952 7954614 YP_002926939.1 CDS fliF NC_012759.1 1903736 1905394 D the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 1903736..1905394 Escherichia coli BW2952 7953582 YP_002926940.1 CDS fliG NC_012759.1 1905387 1906382 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 1905387..1906382 Escherichia coli BW2952 7953583 YP_002926941.1 CDS fliH NC_012759.1 1906375 1907061 D binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 1906375..1907061 Escherichia coli BW2952 7953601 YP_002926942.1 CDS fliI NC_012759.1 1907061 1908434 D involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 1907061..1908434 Escherichia coli BW2952 7953584 YP_002926943.1 CDS fliJ NC_012759.1 1908453 1908896 D rod/hook and filament chaperone; flagellar biosynthesis chaperone 1908453..1908896 Escherichia coli BW2952 7953607 YP_002926944.1 CDS fliK NC_012759.1 1908893 1910020 D MG1655 equivalent: b1943; flagellar hook-length control protein 1908893..1910020 Escherichia coli BW2952 7953604 YP_002926945.1 CDS fliL NC_012759.1 1910125 1910589 D interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 1910125..1910589 Escherichia coli BW2952 7953600 YP_002926946.1 CDS fliM NC_012759.1 1910594 1911598 D with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 1910594..1911598 Escherichia coli BW2952 7953585 YP_002926947.1 CDS fliN NC_012759.1 1911595 1912008 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 1911595..1912008 Escherichia coli BW2952 7953602 YP_002926948.1 CDS fliO NC_012759.1 1912011 1912376 D with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 1912011..1912376 Escherichia coli BW2952 7953603 YP_002926949.1 CDS fliP NC_012759.1 1912376 1913113 D FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 1912376..1913113 Escherichia coli BW2952 7953586 YP_002926950.1 CDS fliQ NC_012759.1 1913123 1913392 D with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 1913123..1913392 Escherichia coli BW2952 7953587 YP_002926951.1 CDS fliR NC_012759.1 1913400 1914185 D FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 1913400..1914185 Escherichia coli BW2952 7953588 YP_002926952.1 CDS rcsA NC_012759.1 1914475 1915098 D MG1655 equivalent: b1951; DNA-binding transcriptional activator, co-regulator with RcsB 1914475..1915098 Escherichia coli BW2952 7953593 YP_002926953.1 CDS dsrB NC_012759.1 1915142 1915330 R MG1655 equivalent: b1952; hypothetical protein complement(1915142..1915330) Escherichia coli BW2952 7953395 YP_002926954.1 CDS yodD NC_012759.1 1915493 1915720 D MG1655 equivalent: b1953; hypothetical protein 1915493..1915720 Escherichia coli BW2952 7955378 YP_002926955.1 CDS yedP NC_012759.1 1916018 1916833 D catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 1916018..1916833 Escherichia coli BW2952 7952086 YP_002926956.1 CDS yedQ NC_012759.1 1916830 1918524 R MG1655 equivalent: b1956; putative diguanylate cyclase complement(1916830..1918524) Escherichia coli BW2952 7952987 YP_002926957.1 CDS yodC NC_012759.1 1918695 1918877 R MG1655 equivalent: b1957; hypothetical protein complement(1918695..1918877) Escherichia coli BW2952 7954723 YP_002926958.1 CDS yedI NC_012759.1 1918956 1919873 R MG1655 equivalent: b1958; hypothetical protein complement(1918956..1919873) Escherichia coli BW2952 7955379 YP_002926959.1 CDS yedA NC_012759.1 1920046 1920966 D MG1655 equivalent: b1959; hypothetical protein 1920046..1920966 Escherichia coli BW2952 7952673 YP_002926960.1 CDS vsr NC_012759.1 1920955 1921425 R MG1655 equivalent: b1960; DNA mismatch endonuclease of very short patch repair complement(1920955..1921425) Escherichia coli BW2952 7955048 YP_002926961.1 CDS dcm NC_012759.1 1921406 1922824 R MG1655 equivalent: b1961; DNA cytosine methylase complement(1921406..1922824) Escherichia coli BW2952 7953314 YP_002926962.1 CDS yedJ NC_012759.1 1922891 1923586 R MG1655 equivalent: b1962; hypothetical protein complement(1922891..1923586) Escherichia coli BW2952 7953302 YP_002926963.1 CDS yedR NC_012759.1 1923626 1923991 R MG1655 equivalent: b1963; putative inner membrane protein complement(1923626..1923991) Escherichia coli BW2952 7955316 YP_002926964.1 CDS hchA NC_012759.1 1926342 1927193 D Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 1926342..1927193 Escherichia coli BW2952 7952181 YP_002926965.1 CDS yedV NC_012759.1 1927301 1928659 R MG1655 equivalent: b1968; putative sensory kinase in two-component regulatory system with YedW complement(1927301..1928659) Escherichia coli BW2952 7953924 YP_002926966.1 CDS yedW NC_012759.1 1928659 1929330 R induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW complement(1928659..1929330) Escherichia coli BW2952 7955586 YP_002926967.1 CDS yedX NC_012759.1 1929463 1929876 D MG1655 equivalent: b1970; hypothetical protein 1929463..1929876 Escherichia coli BW2952 7954742 YP_002926968.1 CDS yedY NC_012759.1 1929985 1930989 D in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; putative sulfite oxidase subunit YedY 1929985..1930989 Escherichia coli BW2952 7952988 YP_002926969.1 CDS yedZ NC_012759.1 1930990 1931625 D in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; putative sulfite oxidase subunit YedZ 1930990..1931625 Escherichia coli BW2952 7955557 YP_002926970.1 CDS yodA NC_012759.1 1931882 1932532 D MG1655 equivalent: b1973; hypothetical protein 1931882..1932532 Escherichia coli BW2952 7952715 YP_002926971.1 CDS yodB NC_012759.1 1932875 1933405 D MG1655 equivalent: b1974; putative cytochrome 1932875..1933405 Escherichia coli BW2952 7952747 YP_002926972.1 CDS mtfA NC_012759.1 1934158 1934955 D MG1655 equivalent: b1976; hypothetical protein 1934158..1934955 Escherichia coli BW2952 7952056 YP_002926973.1 CDS yeeJ NC_012759.1 1935445 1942521 D MG1655 equivalent: b1978; adhesin 1935445..1942521 Escherichia coli BW2952 7952132 YP_002926974.1 CDS shiA NC_012759.1 1944150 1945466 D MG1655 equivalent: b1981; shikimate transporter 1944150..1945466 Escherichia coli BW2952 7952427 YP_002926975.1 CDS amn NC_012759.1 1945568 1947022 D Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 1945568..1947022 Escherichia coli BW2952 7956039 YP_002926976.1 CDS yeeN NC_012759.1 1947365 1948081 D MG1655 equivalent: b1983; hypothetical protein 1947365..1948081 Escherichia coli BW2952 7952475 YP_002926977.1 CDS yeeO NC_012759.1 1948710 1950353 R MG1655 equivalent: b1985; hypothetical protein complement(1948710..1950353) Escherichia coli BW2952 7952057 YP_002926978.1 CDS cbl NC_012759.1 1950471 1951421 R LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl complement(1950471..1951421) Escherichia coli BW2952 7952133 YP_002926979.1 CDS nac NC_012759.1 1951523 1952440 R Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator complement(1951523..1952440) Escherichia coli BW2952 7953389 YP_002926980.1 CDS erfK NC_012759.1 1952898 1953830 R MG1655 equivalent: b1990; hypothetical protein complement(1952898..1953830) Escherichia coli BW2952 7952134 YP_002926981.1 CDS cobT NC_012759.1 1953895 1954974 R catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase complement(1953895..1954974) Escherichia coli BW2952 7953081 YP_002926982.1 CDS cobS NC_012759.1 1954986 1955729 R catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase complement(1954986..1955729) Escherichia coli BW2952 7954384 YP_002926983.1 CDS cobU NC_012759.1 1955726 1956271 R catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase complement(1955726..1956271) Escherichia coli BW2952 7952647 YP_002926984.1 CDS insH NC_012759.1 1956812 1957828 R MG1655 equivalent: b1994; IS5 transposase and trans-activator complement(1956812..1957828) Escherichia coli BW2952 7952564 YP_002926985.1 CDS insD NC_012759.1 1959459 1960364 R IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD complement(1959459..1960364) Escherichia coli BW2952 7954040 YP_002926986.1 CDS insC NC_012759.1 1960322 1960687 R IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein complement(1960322..1960687) Escherichia coli BW2952 7954078 YP_002926987.1 CDS flu NC_012759.1 1962046 1965165 D MG1655 equivalent: b2000; CP4-44 prophage; antigen 43 (Ag43) phase-variable biofilm formation autotransporter 1962046..1965165 Escherichia coli BW2952 7952182 YP_002926988.1 CDS yeeR NC_012759.1 1965286 1966818 D MG1655 equivalent: b2001; CP4-44 prophage; putative membrane protein 1965286..1966818 Escherichia coli BW2952 7953103 YP_002926989.1 CDS yeeS NC_012759.1 1966815 1967261 D MG1655 equivalent: b2002; CP4-44 prophage; putative DNA repair protein 1966815..1967261 Escherichia coli BW2952 7953106 YP_002926990.1 CDS yeeT NC_012759.1 1967324 1967545 D MG1655 equivalent: b2003; CP4-44 prophage protein 1967324..1967545 Escherichia coli BW2952 7953105 YP_002926991.1 CDS yeeU NC_012759.1 1967619 1967987 D MG1655 equivalent: b2004; CP4-44 prophage; antitoxin of the YeeV-YeeU toxin-antitoxin system 1967619..1967987 Escherichia coli BW2952 7953107 YP_002926992.1 CDS yeeV NC_012759.1 1968076 1968450 D MG1655 equivalent: b2005; CP4-44 prophage; toxin of the YeeV-YeeU toxin-antitoxin system 1968076..1968450 Escherichia coli BW2952 7953104 YP_002926993.1 CDS yeeX NC_012759.1 1969539 1969868 R MG1655 equivalent: b2007; hypothetical protein complement(1969539..1969868) Escherichia coli BW2952 7953108 YP_002926994.1 CDS yeeA NC_012759.1 1970040 1971098 R MG1655 equivalent: b2008; hypothetical protein complement(1970040..1971098) Escherichia coli BW2952 7952822 YP_002926995.1 CDS sbmC NC_012759.1 1971296 1971769 R MG1655 equivalent: b2009; DNA gyrase inhibitor complement(1971296..1971769) Escherichia coli BW2952 7952674 YP_002926996.1 CDS dacD NC_012759.1 1971888 1973054 R removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase complement(1971888..1973054) Escherichia coli BW2952 7953307 YP_002926997.1 CDS sbcB NC_012759.1 1973263 1974690 D Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 1973263..1974690 Escherichia coli BW2952 7953220 YP_002926998.1 CDS yeeD NC_012759.1 1974733 1974960 R MG1655 equivalent: b2012; hypothetical protein complement(1974733..1974960) Escherichia coli BW2952 7953539 YP_002926999.1 CDS yeeE NC_012759.1 1974974 1976032 R MG1655 equivalent: b2013; putative inner membrane protein complement(1974974..1976032) Escherichia coli BW2952 7952823 YP_002927000.1 CDS yeeF NC_012759.1 1976211 1977569 R MG1655 equivalent: b2014; putative amino-acid transporter complement(1976211..1977569) Escherichia coli BW2952 7955000 YP_002927001.1 CDS yeeY NC_012759.1 1977836 1978765 R MG1655 equivalent: b2015; putative DNA-binding transcriptional regulator complement(1977836..1978765) Escherichia coli BW2952 7954641 YP_002927002.1 CDS yeeZ NC_012759.1 1978811 1979635 R MG1655 equivalent: b2016; putative epimerase, with NAD(P)-binding Rossmann-fold domain complement(1978811..1979635) Escherichia coli BW2952 7954765 YP_002927003.1 CDS yoeB NC_012759.1 1979718 1979972 R MG1655 equivalent: b4539; toxin of the YoeB-YefM toxin-antitoxin system complement(1979718..1979972) Escherichia coli BW2952 7954860 YP_002927004.1 CDS yefM NC_012759.1 1979969 1980220 R Antitoxin that counteracts the effect of the YoeB toxin; antitoxin YefM complement(1979969..1980220) Escherichia coli BW2952 7956162 YP_002927006.1 CDS hisG NC_012759.1 1980699 1981598 D long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 1980699..1981598 Escherichia coli BW2952 7953908 YP_002927007.1 CDS hisD NC_012759.1 1981604 1982908 D catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 1981604..1982908 Escherichia coli BW2952 7952521 YP_002927008.1 CDS hisC NC_012759.1 1982905 1983975 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1982905..1983975 Escherichia coli BW2952 7952569 YP_002927009.1 CDS hisB NC_012759.1 1983975 1985042 D catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 1983975..1985042 Escherichia coli BW2952 7953913 YP_002927010.1 CDS hisH NC_012759.1 1985042 1985632 D with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 1985042..1985632 Escherichia coli BW2952 7953687 YP_002927011.1 CDS hisA NC_012759.1 1985632 1986369 D catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 1985632..1986369 Escherichia coli BW2952 7953992 YP_002927012.1 CDS hisF NC_012759.1 1986351 1987127 D catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 1986351..1987127 Escherichia coli BW2952 7954326 YP_002927013.1 CDS hisI NC_012759.1 1987121 1987732 D catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 1987121..1987732 Escherichia coli BW2952 7953991 YP_002927014.1 CDS cld NC_012759.1 1987828 1988808 R MG1655 equivalent: b2027; regulator of length of O-antigen component of lipopolysaccharide chains complement(1987828..1988808) Escherichia coli BW2952 7953706 YP_002927015.1 CDS ugd NC_012759.1 1988954 1990120 R MG1655 equivalent: b2028; UDP-glucose 6-dehydrogenase complement(1988954..1990120) Escherichia coli BW2952 7955920 YP_002927016.1 CDS gnd NC_012759.1 1990369 1991775 R catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase complement(1990369..1991775) Escherichia coli BW2952 7956234 YP_002927017.1 CDS insH NC_012759.1 1992402 1993418 R MG1655 equivalent: b2030; IS5 transposase and trans-activator complement(1992402..1993418) Escherichia coli BW2952 7953801 YP_002927018.1 CDS wbbK NC_012759.1 1993898 1995016 R MG1655 equivalent: b2032; lipopolysaccharide biosynthesis protein complement(1993898..1995016) Escherichia coli BW2952 7954041 YP_002927019.1 CDS wbbJ NC_012759.1 1995001 1995591 R WbbJ; catalyzes the transfer of the O-acetyl moiety to the O antigen; part of the lipopolysaccharide biosynthetic pathway; putative lipopolysaccharide biosynthesis O-acetyl transferase WbbJ complement(1995001..1995591) Escherichia coli BW2952 7954149 YP_002927020.1 CDS wbbI NC_012759.1 1995572 1996564 R MG1655 equivalent: b2034; hypothetical protein complement(1995572..1996564) Escherichia coli BW2952 7954606 YP_002927021.1 CDS rfc NC_012759.1 1996567 1997733 R MG1655 equivalent: b2035; O-antigen polymerase complement(1996567..1997733) Escherichia coli BW2952 7952824 YP_002927022.1 CDS glf NC_012759.1 1997733 1998836 R MG1655 equivalent: b2036; UDP-galactopyranose mutase, FAD/NAD(P)-binding complement(1997733..1998836) Escherichia coli BW2952 7954418 YP_002927023.1 CDS rfbX NC_012759.1 1998844 2000091 R MG1655 equivalent: b2037; putative polisoprenol-linked O-antigen transporter complement(1998844..2000091) Escherichia coli BW2952 7956231 YP_002927024.1 CDS rfbC NC_012759.1 2000088 2000645 R MG1655 equivalent: b2038; dTDP-4-deoxyrhamnose-3,5-epimerase complement(2000088..2000645) Escherichia coli BW2952 7955324 YP_002927025.1 CDS rfbA NC_012759.1 2000645 2001526 R MG1655 equivalent: b2039; glucose-1-phosphate thymidylyltransferase complement(2000645..2001526) Escherichia coli BW2952 7953502 YP_002927026.1 CDS rfbD NC_012759.1 2001584 2002483 R with dTDP-4-dehydrorhamnose 3,5-epimerase forms a complex known as dTDP-L-rhamnose synthetase; catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose; dTDP-4-dehydrorhamnose reductase complement(2001584..2002483) Escherichia coli BW2952 7953806 YP_002927027.1 CDS rfbB NC_012759.1 2002483 2003568 R NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose; dTDP-glucose-4,6-dehydratase complement(2002483..2003568) Escherichia coli BW2952 7953501 YP_002927028.1 CDS galF NC_012759.1 2003941 2004834 R together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalF complement(2003941..2004834) Escherichia coli BW2952 7953503 YP_002927029.1 CDS wcaM NC_012759.1 2005009 2006403 R WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; putative colanic acid biosynthesis protein complement(2005009..2006403) Escherichia coli BW2952 7955602 YP_002927030.1 CDS wcaL NC_012759.1 2006414 2007634 R MG1655 equivalent: b2044; putative glycosyl transferase complement(2006414..2007634) Escherichia coli BW2952 7954699 YP_002927031.1 CDS wcaK NC_012759.1 2007631 2008911 R MG1655 equivalent: b2045; putative pyruvyl transferase complement(2007631..2008911) Escherichia coli BW2952 7954933 YP_002927032.1 CDS wzxC NC_012759.1 2009187 2010665 R MG1655 equivalent: b2046; colanic acid exporter complement(2009187..2010665) Escherichia coli BW2952 7955553 YP_002927033.1 CDS wcaJ NC_012759.1 2010667 2012061 R WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; putative UDP-glucose lipid carrier transferase complement(2010667..2012061) Escherichia coli BW2952 7952651 YP_002927034.1 CDS cpsG NC_012759.1 2012116 2013486 R MG1655 equivalent: b2048; phosphomannomutase complement(2012116..2013486) Escherichia coli BW2952 7955745 YP_002927035.1 CDS cpsB NC_012759.1 2013591 2015027 R MG1655 equivalent: b2049; mannose-1-phosphate guanyltransferase complement(2013591..2015027) Escherichia coli BW2952 7954542 YP_002927036.1 CDS wcaI NC_012759.1 2015030 2016253 R MG1655 equivalent: b2050; putative glycosyl transferase complement(2015030..2016253) Escherichia coli BW2952 7954214 YP_002927037.1 CDS gmm NC_012759.1 2016250 2016729 R MG1655 equivalent: b2051; GDP-mannose mannosyl hydrolase complement(2016250..2016729) Escherichia coli BW2952 7954934 YP_002927038.1 CDS fcl NC_012759.1 2016732 2017697 R MG1655 equivalent: b2052; bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase/ GDP-4-dehydro-6-L-deoxygalactose reductase complement(2016732..2017697) Escherichia coli BW2952 7953777 YP_002927039.1 CDS gmd NC_012759.1 2017700 2018821 R MG1655 equivalent: b2053; GDP-D-mannose dehydratase, NAD(P)-binding complement(2017700..2018821) Escherichia coli BW2952 7952568 YP_002927040.1 CDS wcaF NC_012759.1 2018847 2019395 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); putative colanic acid biosynthesis acetyltransferase WcaF complement(2018847..2019395) Escherichia coli BW2952 7953776 YP_002927041.1 CDS wcaE NC_012759.1 2019411 2020157 R MG1655 equivalent: b2055; putative glycosyl transferase complement(2019411..2020157) Escherichia coli BW2952 7954607 YP_002927042.1 CDS wcaD NC_012759.1 2020168 2021385 R essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; putative colanic acid biosynthesis protein complement(2020168..2021385) Escherichia coli BW2952 7954935 YP_002927043.1 CDS wcaC NC_012759.1 2021360 2022577 R MG1655 equivalent: b2057; putative glycosyl transferase complement(2021360..2022577) Escherichia coli BW2952 7954700 YP_002927044.1 CDS wcaB NC_012759.1 2022574 2023062 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; putative colanic acid biosynthesis acetyltransferase WcaB complement(2022574..2023062) Escherichia coli BW2952 7954936 YP_002927045.1 CDS wcaA NC_012759.1 2023065 2023904 R MG1655 equivalent: b2059; putative glycosyl transferase complement(2023065..2023904) Escherichia coli BW2952 7954608 YP_002927046.1 CDS wzc NC_012759.1 2023997 2026159 R Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase complement(2023997..2026159) Escherichia coli BW2952 7954937 YP_002927047.1 CDS wzb NC_012759.1 2026162 2026605 R Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase complement(2026162..2026605) Escherichia coli BW2952 7955812 YP_002927048.1 CDS wza NC_012759.1 2026611 2027750 R MG1655 equivalent: b2062; lipoprotein required for capsular polysaccharide translocation through the outer membrane complement(2026611..2027750) Escherichia coli BW2952 7955813 YP_002927049.1 CDS yegH NC_012759.1 2028409 2029992 D MG1655 equivalent: b2063; fused putative membrane protein/putative membrane protein 2028409..2029992 Escherichia coli BW2952 7954158 YP_002927050.1 CDS asmA NC_012759.1 2030266 2032119 R YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; putative assembly protein complement(2030266..2032119) Escherichia coli BW2952 7953714 YP_002927051.1 CDS dcd NC_012759.1 2032141 2032722 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(2032141..2032722) Escherichia coli BW2952 7954660 YP_002927052.1 CDS udk NC_012759.1 2032814 2033455 R functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase complement(2032814..2033455) Escherichia coli BW2952 7952256 YP_002927053.1 CDS yegE NC_012759.1 2033773 2037090 D contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction; putative sensor protein 2033773..2037090 Escherichia coli BW2952 7956263 YP_002927054.1 CDS alkA NC_012759.1 2037199 2038047 R inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyladenine DNA glycosylase complement(2037199..2038047) Escherichia coli BW2952 7954734 YP_002927055.1 CDS yegD NC_012759.1 2038181 2039533 D MG1655 equivalent: b2069; putative chaperone 2038181..2039533 Escherichia coli BW2952 7952314 YP_002927056.1 CDS yegI NC_012759.1 2039546 2041492 R MG1655 equivalent: b2070; hypothetical protein complement(2039546..2041492) Escherichia coli BW2952 7954689 YP_002927057.1 CDS yegJ NC_012759.1 2041692 2042153 D MG1655 equivalent: b2071; hypothetical protein 2041692..2042153 Escherichia coli BW2952 7952825 YP_002927058.1 CDS yegK NC_012759.1 2042218 2042979 R MG1655 equivalent: b2072; hypothetical protein complement(2042218..2042979) Escherichia coli BW2952 7955488 YP_002927059.1 CDS yegL NC_012759.1 2042976 2043635 R MG1655 equivalent: b2073; hypothetical protein complement(2042976..2043635) Escherichia coli BW2952 7955380 YP_002927060.1 CDS mdtA NC_012759.1 2044523 2045770 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2044523..2045770 Escherichia coli BW2952 7952184 YP_002927061.1 CDS mdtB NC_012759.1 2045770 2048892 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2045770..2048892 Escherichia coli BW2952 7954311 YP_002927062.1 CDS mdtC NC_012759.1 2048893 2051970 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2048893..2051970 Escherichia coli BW2952 7954312 YP_002927063.1 CDS mdtD NC_012759.1 2051971 2053386 D MG1655 equivalent: b2077; multidrug efflux system protein MdtE 2051971..2053386 Escherichia coli BW2952 7954313 YP_002927064.1 CDS baeS NC_012759.1 2053383 2054786 D MG1655 equivalent: b2078; signal transduction histidine-protein kinase BaeS 2053383..2054786 Escherichia coli BW2952 7954302 YP_002927065.1 CDS baeR NC_012759.1 2054783 2055505 D response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2054783..2055505 Escherichia coli BW2952 7956012 YP_002927066.1 CDS yegP NC_012759.1 2055696 2056028 D MG1655 equivalent: b2080; hypothetical protein 2055696..2056028 Escherichia coli BW2952 7953344 YP_002927067.1 CDS yegQ NC_012759.1 2056175 2057536 D MG1655 equivalent: b2081; putative peptidase 2056175..2057536 Escherichia coli BW2952 7955489 YP_002927068.1 CDS ogrK NC_012759.1 2057809 2058027 R in E. coli K-12 this is in prophage P2 remnant; DNA-binding transcriptional regulator complement(2057809..2058027) Escherichia coli BW2952 7952185 YP_002927069.1 CDS yegR NC_012759.1 2058496 2058813 R MG1655 equivalent: b2085; hypothetical protein complement(2058496..2058813) Escherichia coli BW2952 7953448 YP_002927070.1 CDS yegS NC_012759.1 2059219 2060118 D cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2059219..2060118 Escherichia coli BW2952 7955381 YP_002927071.1 CDS insE NC_012759.1 2060734 2061042 D MG1655 equivalent: b2088; IS3 element protein InsE 2060734..2061042 Escherichia coli BW2952 7954520 YP_002927072.1 CDS insF NC_012759.1 2061039 2061905 D MG1655 equivalent: b2089; IS3 element protein InsF 2061039..2061905 Escherichia coli BW2952 7954031 YP_002927073.1 CDS gatD NC_012759.1 2062340 2063380 R Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase complement(2062340..2063380) Escherichia coli BW2952 7954035 YP_002927074.1 CDS gatC NC_012759.1 2063428 2064783 R MG1655 equivalent: b2092; PTS system galactitol-specific transporter subunit IIC complement(2063428..2064783) Escherichia coli BW2952 7953754 YP_002927075.1 CDS gatB NC_012759.1 2064787 2065071 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB complement(2064787..2065071) Escherichia coli BW2952 7953757 YP_002927076.1 CDS gatA NC_012759.1 2065102 2065554 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA complement(2065102..2065554) Escherichia coli BW2952 7953756 YP_002927077.1 CDS gatZ NC_012759.1 2065564 2066826 R MG1655 equivalent: b2095; D-tagatose 1,6-bisphosphate aldolase 2, subunit complement(2065564..2066826) Escherichia coli BW2952 7953755 YP_002927078.1 CDS gatY NC_012759.1 2066855 2067709 R catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase complement(2066855..2067709) Escherichia coli BW2952 7953500 YP_002927079.1 CDS fbaB NC_012759.1 2068017 2069069 R catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase complement(2068017..2069069) Escherichia coli BW2952 7953499 YP_002927080.1 CDS yegT NC_012759.1 2069326 2070603 D MG1655 equivalent: b2098; putative nucleoside transporter 2069326..2070603 Escherichia coli BW2952 7953637 YP_002927081.1 CDS yegU NC_012759.1 2070600 2071604 D MG1655 equivalent: b2099; putative hydrolase 2070600..2071604 Escherichia coli BW2952 7955185 YP_002927082.1 CDS yegV NC_012759.1 2071601 2072566 D MG1655 equivalent: b2100; putative kinase 2071601..2072566 Escherichia coli BW2952 7954968 YP_002927083.1 CDS yegW NC_012759.1 2072540 2073286 R MG1655 equivalent: b2101; putative DNA-binding transcriptional regulator complement(2072540..2073286) Escherichia coli BW2952 7955094 YP_002927084.1 CDS yegX NC_012759.1 2073338 2074156 R MG1655 equivalent: b2102; putative hydrolase complement(2073338..2074156) Escherichia coli BW2952 7954766 YP_002927085.1 CDS thiD NC_012759.1 2074221 2075021 R catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase complement(2074221..2075021) Escherichia coli BW2952 7954956 YP_002927086.1 CDS thiM NC_012759.1 2075018 2075806 R catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase complement(2075018..2075806) Escherichia coli BW2952 7952570 YP_002927087.1 CDS rcnR NC_012759.1 2076029 2076301 R MG1655 equivalent: b2105; hypothetical protein complement(2076029..2076301) Escherichia coli BW2952 7953934 YP_002927088.1 CDS rcnA NC_012759.1 2076422 2077246 D membrane protein conferring nickel and cobalt resistance; nickel/cobalt efflux protein RcnA 2076422..2077246 Escherichia coli BW2952 7952827 YP_002927089.1 CDS yohN NC_012759.1 2077465 2077803 D MG1655 equivalent: b2107; hypothetical protein 2077465..2077803 Escherichia coli BW2952 7954228 YP_002927090.1 CDS yehA NC_012759.1 2077885 2078919 R MG1655 equivalent: b2108; putative fimbrial-like adhesin protein complement(2077885..2078919) Escherichia coli BW2952 7955490 YP_002927091.1 CDS yehB NC_012759.1 2078935 2081415 R MG1655 equivalent: b2109; putative outer membrane protein complement(2078935..2081415) Escherichia coli BW2952 7954886 YP_002927092.1 CDS yehC NC_012759.1 2081431 2082150 R MG1655 equivalent: b2110; putative periplasmic pilin chaperone complement(2081431..2082150) Escherichia coli BW2952 7955212 YP_002927093.1 CDS yehD NC_012759.1 2082185 2082727 R MG1655 equivalent: b2111; putative fimbrial-like adhesin protein complement(2082185..2082727) Escherichia coli BW2952 7955301 YP_002927094.1 CDS yehE NC_012759.1 2083020 2083301 R MG1655 equivalent: b2112; hypothetical protein complement(2083020..2083301) Escherichia coli BW2952 7954887 YP_002927095.1 CDS mrp NC_012759.1 2083564 2084673 R MG1655 equivalent: b2113; putative ATPase complement(2083564..2084673) Escherichia coli BW2952 7955382 YP_002927096.1 CDS metG NC_012759.1 2084805 2086838 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2084805..2086838 Escherichia coli BW2952 7952481 YP_002927097.1 CDS yehI NC_012759.1 2090784 2094416 D MG1655 equivalent: b2118; hypothetical protein 2090784..2094416 Escherichia coli BW2952 7954247 YP_002927098.1 CDS yehK NC_012759.1 2094477 2094794 D MG1655 equivalent: b4541; hypothetical protein 2094477..2094794 Escherichia coli BW2952 7952991 YP_002927099.1 CDS yehL NC_012759.1 2095101 2096189 D MG1655 equivalent: b2119; putative transporter subunit: ATP-binding component of ABC superfamily 2095101..2096189 Escherichia coli BW2952 7955532 YP_002927100.1 CDS yehM NC_012759.1 2096200 2098479 D MG1655 equivalent: b2120; hypothetical protein 2096200..2098479 Escherichia coli BW2952 7955724 YP_002927101.1 CDS yehP NC_012759.1 2098472 2099608 D MG1655 equivalent: b2121; hypothetical protein 2098472..2099608 Escherichia coli BW2952 7955491 YP_002927102.1 CDS yehR NC_012759.1 2101730 2102191 D MG1655 equivalent: b2123; hypothetical protein 2101730..2102191 Escherichia coli BW2952 7952992 YP_002927103.1 CDS yehS NC_012759.1 2102231 2102701 R MG1655 equivalent: b2124; hypothetical protein complement(2102231..2102701) Escherichia coli BW2952 7952993 YP_002927104.1 CDS yehT NC_012759.1 2102748 2103467 R unknown function; when overproduced it confers drug-resistance; putative two-component response-regulatory protein YehT complement(2102748..2103467) Escherichia coli BW2952 7952828 YP_002927105.1 CDS yehU NC_012759.1 2103464 2105149 R MG1655 equivalent: b2126; putative sensory kinase in two-component system with YehT complement(2103464..2105149) Escherichia coli BW2952 7955567 YP_002927106.1 CDS mlrA NC_012759.1 2105371 2106102 D MG1655 equivalent: b2127; DNA-binding transcriptional regulator 2105371..2106102 Escherichia coli BW2952 7955588 YP_002927107.1 CDS yohO NC_012759.1 2106162 2106269 D MG1655 equivalent: b4542; hypothetical protein 2106162..2106269 Escherichia coli BW2952 7953444 YP_002927108.1 CDS yehW NC_012759.1 2106250 2106981 R MG1655 equivalent: b2128; putative transporter subunit: membrane component of ABC superfamily complement(2106250..2106981) Escherichia coli BW2952 7955533 YP_002927109.1 CDS yehX NC_012759.1 2106986 2107912 R MG1655 equivalent: b2129; putative transporter subunit: ATP-binding component of ABC superfamily complement(2106986..2107912) Escherichia coli BW2952 7955729 YP_002927110.1 CDS yehY NC_012759.1 2107905 2109062 R MG1655 equivalent: b2130; putative transporter subunit: membrane component of ABC superfamily complement(2107905..2109062) Escherichia coli BW2952 7955718 YP_002927111.1 CDS osmF NC_012759.1 2109069 2109986 R MG1655 equivalent: b2131; putative transporter subunit: periplasmic-binding component of ABC superfamily complement(2109069..2109986) Escherichia coli BW2952 7955730 YP_002927112.1 CDS bglX NC_012759.1 2110197 2112494 R MG1655 equivalent: b2132; beta-D-glucoside glucohydrolase, periplasmic complement(2110197..2112494) Escherichia coli BW2952 7955735 YP_002927113.1 CDS dld NC_012759.1 2112690 2114405 D component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2112690..2114405 Escherichia coli BW2952 7952546 YP_002927114.1 CDS pbpG NC_012759.1 2114443 2115375 R specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase complement(2114443..2115375) Escherichia coli BW2952 7953272 YP_002927115.1 CDS yohC NC_012759.1 2115549 2116136 R MG1655 equivalent: b2135; putative inner membrane protein complement(2115549..2116136) Escherichia coli BW2952 7953221 YP_002927116.1 CDS yohD NC_012759.1 2116306 2116884 D MG1655 equivalent: b2136; hypothetical protein 2116306..2116884 Escherichia coli BW2952 7955001 YP_002927117.1 CDS yohF NC_012759.1 2117014 2117775 R MG1655 equivalent: b2137; acetoin dehydrogenase complement(2117014..2117775) Escherichia coli BW2952 7952716 YP_002927118.1 CDS dusC NC_012759.1 2119943 2120890 R MG1655 equivalent: b2140; tRNA-dihydrouridine synthase C complement(2119943..2120890) Escherichia coli BW2952 7955246 YP_002927119.1 CDS yohJ NC_012759.1 2121129 2121527 D MG1655 equivalent: b2141; hypothetical protein 2121129..2121527 Escherichia coli BW2952 7956206 YP_002927120.1 CDS yohK NC_012759.1 2121524 2122219 D MG1655 equivalent: b2142; hypothetical protein 2121524..2122219 Escherichia coli BW2952 7952717 YP_002927121.1 CDS cdd NC_012759.1 2122349 2123233 D Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2122349..2123233 Escherichia coli BW2952 7955049 YP_002927122.1 CDS sanA NC_012759.1 2123383 2124102 D MG1655 equivalent: b2144; hypothetical protein 2123383..2124102 Escherichia coli BW2952 7953188 YP_002927123.1 CDS yeiS NC_012759.1 2124105 2124344 D MG1655 equivalent: b2145; putative inner membrane protein 2124105..2124344 Escherichia coli BW2952 7955492 YP_002927124.1 CDS yeiT NC_012759.1 2124538 2125776 D function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; putative oxidoreductase 2124538..2125776 Escherichia coli BW2952 7955050 YP_002927125.1 CDS yeiA NC_012759.1 2125770 2127005 D catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2125770..2127005 Escherichia coli BW2952 7955234 YP_002927126.1 CDS mglC NC_012759.1 2127248 2128258 R ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein complement(2127248..2128258) Escherichia coli BW2952 7955235 YP_002927127.1 CDS mglA NC_012759.1 2128274 2129794 R with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein complement(2128274..2129794) Escherichia coli BW2952 7954257 YP_002927128.1 CDS mglB NC_012759.1 2129855 2130853 R MG1655 equivalent: b2150; methyl-galactoside transporter subunit complement(2129855..2130853) Escherichia coli BW2952 7953700 YP_002927129.1 CDS galS NC_012759.1 2131133 2132173 R negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS complement(2131133..2132173) Escherichia coli BW2952 7954258 YP_002927130.1 CDS yeiB NC_012759.1 2132315 2133472 R MG1655 equivalent: b2152; hypothetical protein complement(2132315..2133472) Escherichia coli BW2952 7953453 YP_002927131.1 CDS folE NC_012759.1 2133489 2134157 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(2133489..2134157) Escherichia coli BW2952 7952675 YP_002927132.1 CDS yeiG NC_012759.1 2134415 2135251 D MG1655 equivalent: b2154; putative esterase 2134415..2135251 Escherichia coli BW2952 7953874 YP_002927133.1 CDS cirA NC_012759.1 2135283 2137274 R Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor complement(2135283..2137274) Escherichia coli BW2952 7954863 YP_002927134.1 CDS lysP NC_012759.1 2137568 2139037 R MG1655 equivalent: b2156; lysine transporter complement(2137568..2139037) Escherichia coli BW2952 7953569 YP_002927135.1 CDS yeiE NC_012759.1 2139242 2140123 R MG1655 equivalent: b2157; putative DNA-binding transcriptional regulator complement(2139242..2140123) Escherichia coli BW2952 7954182 YP_002927136.1 CDS yeiH NC_012759.1 2140222 2141271 D MG1655 equivalent: b2158; hypothetical protein 2140222..2141271 Escherichia coli BW2952 7954767 YP_002927137.1 CDS nfo NC_012759.1 2141345 2142202 D Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2141345..2142202 Escherichia coli BW2952 7952718 YP_002927138.1 CDS yeiI NC_012759.1 2142205 2143293 D MG1655 equivalent: b2160; hypothetical protein 2142205..2143293 Escherichia coli BW2952 7953517 YP_002927139.1 CDS nupX NC_012759.1 2143400 2144650 R MG1655 equivalent: b2161; putative nucleoside transporter complement(2143400..2144650) Escherichia coli BW2952 7955095 YP_002927140.1 CDS rihB NC_012759.1 2144750 2145691 R Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 complement(2144750..2145691) Escherichia coli BW2952 7955183 YP_002927141.1 CDS yeiL NC_012759.1 2145860 2146519 D activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 2145860..2146519 Escherichia coli BW2952 7955967 YP_002927142.1 CDS yeiM NC_012759.1 2146590 2147840 R MG1655 equivalent: b2164; putative nucleoside transporter complement(2146590..2147840) Escherichia coli BW2952 7953393 YP_002927143.1 CDS yeiN NC_012759.1 2147934 2148872 R MG1655 equivalent: b2165; hypothetical protein complement(2147934..2148872) Escherichia coli BW2952 7955184 YP_002927144.1 CDS yeiC NC_012759.1 2148860 2149801 R MG1655 equivalent: b2166; hypothetical protein complement(2148860..2149801) Escherichia coli BW2952 7952829 YP_002927145.1 CDS fruA NC_012759.1 2150224 2151915 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunit IIBC complement(2150224..2151915) Escherichia coli BW2952 7955093 YP_002927146.1 CDS fruK NC_012759.1 2151229 2151939 D MG1655 equivalent: b2168; fructose-1-phosphate kinase 2151229..2151939 Escherichia coli BW2952 7953681 YP_002927147.1 CDS lpxT NC_012759.1 2152837 2153394 D MG1655 equivalent: b2174; UDP pyrophosphate phosphatase 2152837..2153394 Escherichia coli BW2952 7956298 YP_002927148.1 CDS spr NC_012759.1 2153806 2154372 D by similarity, Spr seems to have peptidase activity; involved in thermoresistance; putative outer membrane lipoprotein 2153806..2154372 Escherichia coli BW2952 7956251 YP_002927149.1 CDS rtn NC_012759.1 2154553 2156109 D MG1655 equivalent: b2176; hypothetical protein 2154553..2156109 Escherichia coli BW2952 7955292 YP_002927150.1 CDS yejA NC_012759.1 2156191 2158005 D MG1655 equivalent: b2177; putative oligopeptide transporter subunit 2156191..2158005 Escherichia coli BW2952 7952994 YP_002927151.1 CDS yejB NC_012759.1 2158006 2159100 D MG1655 equivalent: b2178; putative oligopeptide transporter subunit 2158006..2159100 Escherichia coli BW2952 7955192 YP_002927152.1 CDS yejE NC_012759.1 2159100 2160125 D MG1655 equivalent: b2179; putative oligopeptide transporter subunit 2159100..2160125 Escherichia coli BW2952 7955193 YP_002927153.1 CDS yejF NC_012759.1 2160127 2161716 D MG1655 equivalent: b2180; fused putative oligopeptide transporter subunits of ABC superfamilly: ATP-binding components 2160127..2161716 Escherichia coli BW2952 7955194 YP_002927154.1 CDS yejG NC_012759.1 2161720 2162064 R MG1655 equivalent: b2181; hypothetical protein complement(2161720..2162064) Escherichia coli BW2952 7953719 YP_002927155.1 CDS bcr NC_012759.1 2162397 2163587 R Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein complement(2162397..2163587) Escherichia coli BW2952 7955383 YP_002927156.1 CDS rsuA NC_012759.1 2163615 2164310 R catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A complement(2163615..2164310) Escherichia coli BW2952 7952554 YP_002927157.1 CDS yejH NC_012759.1 2164459 2166219 D MG1655 equivalent: b2184; ATP-dependent helicase 2164459..2166219 Escherichia coli BW2952 7952225 YP_002927158.1 CDS rplY NC_012759.1 2166344 2166628 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 2166344..2166628 Escherichia coli BW2952 7954665 YP_002927159.1 CDS yejK NC_012759.1 2166767 2167774 R MG1655 equivalent: b2186; nucleoid-associated protein NdpA complement(2166767..2167774) Escherichia coli BW2952 7952353 YP_002927160.1 CDS yejL NC_012759.1 2167956 2168183 D MG1655 equivalent: b2187; hypothetical protein 2167956..2168183 Escherichia coli BW2952 7954414 YP_002927161.1 CDS yejM NC_012759.1 2168203 2169963 D MG1655 equivalent: b2188; putative hydrolase, inner membrane 2168203..2169963 Escherichia coli BW2952 7952995 YP_002927162.1 CDS insH NC_012759.1 2172892 2173908 R MG1655 equivalent: b2192; IS5 transposase and trans-activator complement(2172892..2173908) Escherichia coli BW2952 7952135 YP_002927163.1 CDS narP NC_012759.1 2174327 2174974 D nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 2174327..2174974 Escherichia coli BW2952 7954042 YP_002927164.1 CDS ccmH NC_012759.1 2175185 2176237 R MG1655 equivalent: b2194; heme lyase, CcmH subunit complement(2175185..2176237) Escherichia coli BW2952 7953355 YP_002927165.1 CDS ccmG NC_012759.1 2176234 2176791 R MG1655 equivalent: b2195; periplasmic thioredoxin of cytochrome c-type biogenesis complement(2176234..2176791) Escherichia coli BW2952 7953903 YP_002927166.1 CDS ccmF NC_012759.1 2176788 2178731 R MG1655 equivalent: b2196; heme lyase, CcmF subunit complement(2176788..2178731) Escherichia coli BW2952 7954501 YP_002927167.1 CDS ccmE NC_012759.1 2178728 2179207 R CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE complement(2178728..2179207) Escherichia coli BW2952 7953902 YP_002927168.1 CDS ccmD NC_012759.1 2179204 2179413 R MG1655 equivalent: b2198; cytochrome c biogenesis protein complement(2179204..2179413) Escherichia coli BW2952 7954492 YP_002927169.1 CDS ccmC NC_012759.1 2179410 2180147 R MG1655 equivalent: b2199; heme exporter subunit complement(2179410..2180147) Escherichia coli BW2952 7953193 YP_002927170.1 CDS ccmB NC_012759.1 2180189 2180851 R MG1655 equivalent: b2200; heme exporter subunit complement(2180189..2180851) Escherichia coli BW2952 7953896 YP_002927171.1 CDS ccmA NC_012759.1 2180848 2181471 R ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA complement(2180848..2181471) Escherichia coli BW2952 7953897 YP_002927172.1 CDS napC NC_012759.1 2181484 2182086 R with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC complement(2181484..2182086) Escherichia coli BW2952 7953898 YP_002927173.1 CDS napB NC_012759.1 2182096 2182545 R small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit complement(2182096..2182545) Escherichia coli BW2952 7954394 YP_002927174.1 CDS napH NC_012759.1 2182542 2183405 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component complement(2182542..2183405) Escherichia coli BW2952 7954396 YP_002927175.1 CDS napG NC_012759.1 2183392 2184087 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component complement(2183392..2184087) Escherichia coli BW2952 7953565 YP_002927176.1 CDS napA NC_012759.1 2184094 2186580 R periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit complement(2184094..2186580) Escherichia coli BW2952 7953566 YP_002927177.1 CDS napD NC_012759.1 2186577 2186840 R MG1655 equivalent: b2207; assembly protein for periplasmic nitrate reductase complement(2186577..2186840) Escherichia coli BW2952 7954395 YP_002927178.1 CDS napF NC_012759.1 2186830 2187324 R Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA.; ferredoxin-type protein complement(2186830..2187324) Escherichia coli BW2952 7952519 YP_002927179.1 CDS yojO NC_012759.1 2187433 2187597 D MG1655 equivalent: b4604; hypothetical protein 2187433..2187597 Escherichia coli BW2952 7953567 YP_002927180.1 CDS eco NC_012759.1 2187732 2188220 D serine protease inhibitor, inhibits trypsin and other proteases; ecotin 2187732..2188220 Escherichia coli BW2952 7953981 YP_002927181.1 CDS mqo NC_012759.1 2188935 2190581 R malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase complement(2188935..2190581) Escherichia coli BW2952 7953513 YP_002927182.1 CDS yojI NC_012759.1 2190799 2192442 R efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane protein/ATP-binding component complement(2190799..2192442) Escherichia coli BW2952 7954198 YP_002927183.1 CDS alkB NC_012759.1 2192518 2193168 R MG1655 equivalent: b2212; oxidative demethylase of N1-methyladenine or N3-methylcytosine DNA lesions complement(2192518..2193168) Escherichia coli BW2952 7953715 YP_002927184.1 CDS ada NC_012759.1 2193168 2194232 R MG1655 equivalent: b2213; fused DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase complement(2193168..2194232) Escherichia coli BW2952 7954455 YP_002927185.1 CDS apbE NC_012759.1 2194306 2195361 R catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE complement(2194306..2195361) Escherichia coli BW2952 7953675 YP_002927186.1 CDS ompC NC_012759.1 2195473 2196576 R allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C complement(2195473..2196576) Escherichia coli BW2952 7955619 YP_002927187.1 CDS rcsD NC_012759.1 2197315 2199987 D MG1655 equivalent: b2216; phosphotransfer intermediate protein in two-component regulatory system with RcsBC 2197315..2199987 Escherichia coli BW2952 7952186 YP_002927188.1 CDS rcsB NC_012759.1 2200004 2200654 D two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 2200004..2200654 Escherichia coli BW2952 7954555 YP_002927189.1 CDS rcsC NC_012759.1 2200854 2203703 R MG1655 equivalent: b2218; hybrid sensory kinase in two-component regulatory system with RcsB and YojN complement(2200854..2203703) Escherichia coli BW2952 7953360 YP_002927190.1 CDS atoS NC_012759.1 2203870 2205696 D with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; sensory histidine kinase AtoS 2203870..2205696 Escherichia coli BW2952 7953932 YP_002927191.1 CDS atoC NC_012759.1 2205693 2207078 D with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; acetoacetate metabolism regulatory protein AtoC 2205693..2207078 Escherichia coli BW2952 7956011 YP_002927192.1 CDS atoD NC_012759.1 2207274 2207936 D MG1655 equivalent: b2221; acetyl-CoA:acetoacetyl-CoA transferase subunit alpha 2207274..2207936 Escherichia coli BW2952 7953738 YP_002927193.1 CDS atoA NC_012759.1 2207936 2208586 D MG1655 equivalent: b2222; acetyl-CoA:acetoacetyl-CoA transferase, beta subunit 2207936..2208586 Escherichia coli BW2952 7952403 YP_002927194.1 CDS atoE NC_012759.1 2208583 2209905 D MG1655 equivalent: b2223; short chain fatty acid transporter 2208583..2209905 Escherichia coli BW2952 7952404 YP_002927195.1 CDS atoB NC_012759.1 2209936 2211120 D MG1655 equivalent: b2224; acetyl-CoA acetyltransferase 2209936..2211120 Escherichia coli BW2952 7956041 YP_002927196.1 CDS yfaP NC_012759.1 2211194 2211970 R MG1655 equivalent: b2225; hypothetical protein complement(2211194..2211970) Escherichia coli BW2952 7952398 YP_002927197.1 CDS yfaQ NC_012759.1 2211975 2213624 R MG1655 equivalent: b2226; hypothetical protein complement(2211975..2213624) Escherichia coli BW2952 7952830 YP_002927198.1 CDS yfaT NC_012759.1 2218163 2218786 R MG1655 equivalent: b2229; hypothetical protein complement(2218163..2218786) Escherichia coli BW2952 7955384 YP_002927199.1 CDS yfaA NC_012759.1 2218783 2220471 R MG1655 equivalent: b2230; hypothetical protein complement(2218783..2220471) Escherichia coli BW2952 7955385 YP_002927200.1 CDS gyrA NC_012759.1 2220620 2223247 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A complement(2220620..2223247) Escherichia coli BW2952 7955386 YP_002927201.1 CDS ubiG NC_012759.1 2223394 2224116 D Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 2223394..2224116 Escherichia coli BW2952 7953306 YP_002927202.1 CDS yfaL NC_012759.1 2224244 2227996 R MG1655 equivalent: b2233; adhesin complement(2224244..2227996) Escherichia coli BW2952 7952558 YP_002927203.1 CDS ypaB NC_012759.1 2228421 2228564 R MG1655 equivalent: b4605; hypothetical protein complement(2228421..2228564) Escherichia coli BW2952 7952426 YP_002927204.1 CDS nrdA NC_012759.1 2228692 2230977 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2228692..2230977 Escherichia coli BW2952 7953968 YP_002927205.1 CDS nrdB NC_012759.1 2231211 2232341 D B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 2231211..2232341 Escherichia coli BW2952 7955964 YP_002927206.1 CDS yfaE NC_012759.1 2232341 2232595 D plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 2232341..2232595 Escherichia coli BW2952 7955965 YP_002927207.1 CDS inaA NC_012759.1 2232649 2233299 R MG1655 equivalent: b2237; hypothetical protein complement(2232649..2233299) Escherichia coli BW2952 7954586 YP_002927208.1 CDS glpQ NC_012759.1 2233762 2234838 R hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase complement(2233762..2234838) Escherichia coli BW2952 7952831 YP_002927209.1 CDS glpT NC_012759.1 2234843 2236201 R catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter complement(2234843..2236201) Escherichia coli BW2952 7954491 YP_002927210.1 CDS glpA NC_012759.1 2236474 2238102 D anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 2236474..2238102 Escherichia coli BW2952 7956054 YP_002927211.1 CDS glpB NC_012759.1 2238092 2239351 D sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 2238092..2239351 Escherichia coli BW2952 7956050 YP_002927212.1 CDS glpC NC_012759.1 2239348 2240538 D anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 2239348..2240538 Escherichia coli BW2952 7956051 YP_002927213.1 CDS yfaD NC_012759.1 2240731 2241630 D MG1655 equivalent: b2244; hypothetical protein 2240731..2241630 Escherichia coli BW2952 7956052 YP_002927214.1 CDS ypaA NC_012759.1 2241643 2241828 D MG1655 equivalent: b4543; hypothetical protein 2241643..2241828 Escherichia coli BW2952 7952996 YP_002927215.1 CDS yfaU NC_012759.1 2241869 2242672 R MG1655 equivalent: b2245; putative aldolase complement(2241869..2242672) Escherichia coli BW2952 7955534 YP_002927216.1 CDS yfaV NC_012759.1 2242690 2243979 R MG1655 equivalent: b2246; putative transporter complement(2242690..2243979) Escherichia coli BW2952 7954583 YP_002927217.1 CDS yfaW NC_012759.1 2244036 2245253 R MG1655 equivalent: b2247; putative enolase complement(2244036..2245253) Escherichia coli BW2952 7955659 YP_002927218.1 CDS yfaX NC_012759.1 2245256 2246038 R MG1655 equivalent: b2248; putative DNA-binding transcriptional regulator complement(2245256..2246038) Escherichia coli BW2952 7954837 YP_002927219.1 CDS yfaY NC_012759.1 2246258 2247460 R MG1655 equivalent: b2249; competence damage-inducible protein A complement(2246258..2247460) Escherichia coli BW2952 7954768 YP_002927220.1 CDS yfaZ NC_012759.1 2247560 2248102 R MG1655 equivalent: b2250; putative outer membrane porin protein complement(2247560..2248102) Escherichia coli BW2952 7952832 YP_002927221.1 CDS nudI NC_012759.1 2248381 2248806 D MG1655 equivalent: b2251; putative NUDIX hydrolase 2248381..2248806 Escherichia coli BW2952 7955209 YP_002927222.1 CDS ais NC_012759.1 2248845 2249447 R MG1655 equivalent: b2252; hypothetical protein complement(2248845..2249447) Escherichia coli BW2952 7955191 YP_002927223.1 CDS arnB NC_012759.1 2249755 2250894 D catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 2249755..2250894 Escherichia coli BW2952 7952833 YP_002927224.1 CDS arnC NC_012759.1 2250898 2251866 D catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; UDP phosphate 4-deoxy-4-formamido-L-arabinose transferase 2250898..2251866 Escherichia coli BW2952 7956261 YP_002927225.1 CDS arnA NC_012759.1 2251866 2253848 D Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 2251866..2253848 Escherichia coli BW2952 7956247 YP_002927226.1 CDS arnD NC_012759.1 2253845 2254735 D MG1655 equivalent: b2256; hypothetical protein 2253845..2254735 Escherichia coli BW2952 7953751 YP_002927227.1 CDS arnT NC_012759.1 2254735 2256387 D catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 2254735..2256387 Escherichia coli BW2952 7952997 YP_002927228.1 CDS arnE NC_012759.1 2256384 2256719 D MG1655 equivalent: b4544; hypothetical protein 2256384..2256719 Escherichia coli BW2952 7952329 YP_002927229.1 CDS arnF NC_012759.1 2256719 2257105 D MG1655 equivalent: b2258; hypothetical protein 2256719..2257105 Escherichia coli BW2952 7953074 YP_002927230.1 CDS pmrD NC_012759.1 2257099 2257365 R MG1655 equivalent: b2259; polymyxin resistance protein B complement(2257099..2257365) Escherichia coli BW2952 7955051 YP_002927231.1 CDS menE NC_012759.1 2257475 2258830 R MG1655 equivalent: b2260; O-succinylbenzoic acid--CoA ligase complement(2257475..2258830) Escherichia coli BW2952 7954567 YP_002927232.1 CDS menC NC_012759.1 2258827 2259789 R catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase complement(2258827..2259789) Escherichia coli BW2952 7954435 YP_002927233.1 CDS menB NC_012759.1 2259789 2260646 R catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase complement(2259789..2260646) Escherichia coli BW2952 7954436 YP_002927234.1 CDS yfbB NC_012759.1 2260661 2261419 R catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB complement(2260661..2261419) Escherichia coli BW2952 7953260 YP_002927235.1 CDS menD NC_012759.1 2261416 2263086 R SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase complement(2261416..2263086) Escherichia coli BW2952 7955274 YP_002927236.1 CDS menF NC_012759.1 2263175 2264470 R MG1655 equivalent: b2265; isochorismate synthase 2 complement(2263175..2264470) Escherichia coli BW2952 7952557 YP_002927237.1 CDS elaB NC_012759.1 2264549 2264854 R MG1655 equivalent: b2266; hypothetical protein complement(2264549..2264854) Escherichia coli BW2952 7954050 YP_002927238.1 CDS elaA NC_012759.1 2264909 2265370 R MG1655 equivalent: b2267; hypothetical protein complement(2264909..2265370) Escherichia coli BW2952 7952834 YP_002927239.1 CDS rbn NC_012759.1 2265435 2266352 D member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 2265435..2266352 Escherichia coli BW2952 7954616 YP_002927240.1 CDS elaD NC_012759.1 2266540 2267751 D ElaD; specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins; SseL in Salmonella is required for macrophage killing and virulence, and it is secreted by the salmonella pathogenicity island 2 type III secretion system; deubiquitinase 2266540..2267751 Escherichia coli BW2952 7952576 YP_002927241.1 CDS yfbK NC_012759.1 2267822 2269549 R MG1655 equivalent: b2270; hypothetical protein complement(2267822..2269549) Escherichia coli BW2952 7954845 YP_002927242.1 CDS yfbL NC_012759.1 2269687 2270658 D MG1655 equivalent: b2271; putative peptidase 2269687..2270658 Escherichia coli BW2952 7952835 YP_002927243.1 CDS yfbM NC_012759.1 2270761 2271264 D MG1655 equivalent: b2272; hypothetical protein 2270761..2271264 Escherichia coli BW2952 7955282 YP_002927244.1 CDS yfbN NC_012759.1 2271537 2272253 R MG1655 equivalent: b2273; hypothetical protein complement(2271537..2272253) Escherichia coli BW2952 7955493 YP_002927245.1 CDS yfbO NC_012759.1 2272408 2272884 D MG1655 equivalent: b2274; hypothetical protein 2272408..2272884 Escherichia coli BW2952 7955387 YP_002927246.1 CDS yfbP NC_012759.1 2272940 2273791 D MG1655 equivalent: b2275; hypothetical protein 2272940..2273791 Escherichia coli BW2952 7955494 YP_002927247.1 CDS nuoN NC_012759.1 2273875 2275332 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N complement(2273875..2275332) Escherichia coli BW2952 7955495 YP_002927248.1 CDS nuoM NC_012759.1 2275339 2276868 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M complement(2275339..2276868) Escherichia coli BW2952 7954368 YP_002927249.1 CDS nuoL NC_012759.1 2277032 2278873 R Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L complement(2277032..2278873) Escherichia coli BW2952 7954367 YP_002927250.1 CDS nuoK NC_012759.1 2278870 2279172 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K complement(2278870..2279172) Escherichia coli BW2952 7954366 YP_002927251.1 CDS nuoJ NC_012759.1 2279169 2279723 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J complement(2279169..2279723) Escherichia coli BW2952 7954365 YP_002927252.1 CDS nuoI NC_012759.1 2279735 2280277 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I complement(2279735..2280277) Escherichia coli BW2952 7954364 YP_002927253.1 CDS nuoH NC_012759.1 2280292 2281269 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H complement(2280292..2281269) Escherichia coli BW2952 7954361 YP_002927254.1 CDS nuoG NC_012759.1 2281266 2283992 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G complement(2281266..2283992) Escherichia coli BW2952 7954363 YP_002927255.1 CDS nuoF NC_012759.1 2284045 2285382 R shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F complement(2284045..2285382) Escherichia coli BW2952 7954360 YP_002927256.1 CDS nuoE NC_012759.1 2285379 2285879 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E complement(2285379..2285879) Escherichia coli BW2952 7954359 YP_002927257.1 CDS nuoC NC_012759.1 2285882 2287672 R NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D complement(2285882..2287672) Escherichia coli BW2952 7954358 YP_002927258.1 CDS nuoB NC_012759.1 2287778 2288440 R The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B complement(2287778..2288440) Escherichia coli BW2952 7954357 YP_002927259.1 CDS nuoA NC_012759.1 2288456 2288899 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A complement(2288456..2288899) Escherichia coli BW2952 7954356 YP_002927260.1 CDS lrhA NC_012759.1 2289530 2290468 R MG1655 equivalent: b2289; DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes complement(2289530..2290468) Escherichia coli BW2952 7954362 YP_002927261.1 CDS yfbQ NC_012759.1 2291388 2292605 D broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 2291388..2292605 Escherichia coli BW2952 7953472 YP_002927262.1 CDS yfbR NC_012759.1 2292689 2293288 D MG1655 equivalent: b2291; hypothetical protein 2292689..2293288 Escherichia coli BW2952 7954647 YP_002927263.1 CDS yfbS NC_012759.1 2293347 2295179 R MG1655 equivalent: b2292; putative transporter complement(2293347..2295179) Escherichia coli BW2952 7953236 YP_002927264.1 CDS yfbT NC_012759.1 2295266 2295916 R MG1655 equivalent: b2293; putative phosphatase complement(2295266..2295916) Escherichia coli BW2952 7955660 YP_002927265.1 CDS yfbU NC_012759.1 2295927 2296421 R MG1655 equivalent: b2294; hypothetical protein complement(2295927..2296421) Escherichia coli BW2952 7954976 YP_002927266.1 CDS yfbV NC_012759.1 2296504 2296959 R MG1655 equivalent: b2295; hypothetical protein complement(2296504..2296959) Escherichia coli BW2952 7952836 YP_002927267.1 CDS ackA NC_012759.1 2297297 2298499 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 2297297..2298499 Escherichia coli BW2952 7952676 YP_002927268.1 CDS pta NC_012759.1 2298574 2300718 D catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 2298574..2300718 Escherichia coli BW2952 7952388 YP_002927269.1 CDS yfcC NC_012759.1 2300908 2302428 D MG1655 equivalent: b2298; hypothetical protein 2300908..2302428 Escherichia coli BW2952 7954513 YP_002927270.1 CDS yfcD NC_012759.1 2302461 2303003 R MG1655 equivalent: b2299; putative NUDIX hydrolase complement(2302461..2303003) Escherichia coli BW2952 7955052 YP_002927271.1 CDS yfcE NC_012759.1 2303061 2303615 R MG1655 equivalent: b2300; phosphodiesterase complement(2303061..2303615) Escherichia coli BW2952 7955188 YP_002927272.1 CDS yfcF NC_012759.1 2303668 2304312 R MG1655 equivalent: b2301; putative enzyme complement(2303668..2304312) Escherichia coli BW2952 7955311 YP_002927273.1 CDS yfcG NC_012759.1 2304448 2305095 D MG1655 equivalent: b2302; glutathione S-transferase 2304448..2305095 Escherichia coli BW2952 7954841 YP_002927274.1 CDS folX NC_012759.1 2305152 2305514 D catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 2305152..2305514 Escherichia coli BW2952 7954928 YP_002927275.1 CDS yfcH NC_012759.1 2305535 2306428 D MG1655 equivalent: b2304; hypothetical protein 2305535..2306428 Escherichia coli BW2952 7953239 YP_002927276.1 CDS yfcI NC_012759.1 2306476 2307366 R MG1655 equivalent: b2305; hypothetical protein complement(2306476..2307366) Escherichia coli BW2952 7953082 YP_002927277.1 CDS hisP NC_012759.1 2307563 2308336 R MG1655 equivalent: b2306; histidine/lysine/arginine/ornithine transporter subunit complement(2307563..2308336) Escherichia coli BW2952 7952837 YP_002927278.1 CDS hisM NC_012759.1 2308344 2309060 R MG1655 equivalent: b2307; histidine/lysine/arginine/ornithine transporter subunit complement(2308344..2309060) Escherichia coli BW2952 7953909 YP_002927279.1 CDS hisQ NC_012759.1 2309057 2309743 R MG1655 equivalent: b2308; histidine/lysine/arginine/ornithine transporter subunit complement(2309057..2309743) Escherichia coli BW2952 7953910 YP_002927280.1 CDS hisJ NC_012759.1 2309833 2310615 R MG1655 equivalent: b2309; histidine/lysine/arginine/ornithine transporter subunit complement(2309833..2310615) Escherichia coli BW2952 7953911 YP_002927281.1 CDS argT NC_012759.1 2310836 2311618 R MG1655 equivalent: b2310; lysine/arginine/ornithine transporter subunit complement(2310836..2311618) Escherichia coli BW2952 7953912 YP_002927282.1 CDS ubiX NC_012759.1 2311884 2312453 R catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(2311884..2312453) Escherichia coli BW2952 7954185 YP_002927283.1 CDS purF NC_012759.1 2312548 2314065 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(2312548..2314065) Escherichia coli BW2952 7952315 YP_002927284.1 CDS cvpA NC_012759.1 2314102 2314590 R membrane protein required for colicin V production; colicin V production protein complement(2314102..2314590) Escherichia coli BW2952 7952463 YP_002927285.1 CDS dedD NC_012759.1 2314849 2315511 R MG1655 equivalent: b2314; hypothetical protein complement(2314849..2315511) Escherichia coli BW2952 7954231 YP_002927286.1 CDS folC NC_012759.1 2315501 2316769 R MG1655 equivalent: b2315; bifunctional folylpolyglutamate synthase/ dihydrofolate synthase complement(2315501..2316769) Escherichia coli BW2952 7952838 YP_002927287.1 CDS accD NC_012759.1 2316839 2317753 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta complement(2316839..2317753) Escherichia coli BW2952 7952567 YP_002927288.1 CDS dedA NC_012759.1 2317909 2318568 R MG1655 equivalent: b2317; hypothetical protein complement(2317909..2318568) Escherichia coli BW2952 7952399 YP_002927289.1 CDS truA NC_012759.1 2318651 2319463 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(2318651..2319463) Escherichia coli BW2952 7952677 YP_002927290.1 CDS usg NC_012759.1 2319463 2320476 R MG1655 equivalent: b2319; putative semialdehyde dehydrogenase complement(2319463..2320476) Escherichia coli BW2952 7955821 YP_002927291.1 CDS pdxB NC_012759.1 2320542 2321678 R MG1655 equivalent: b2320; erythronate-4-phosphate dehydrogenase complement(2320542..2321678) Escherichia coli BW2952 7955585 YP_002927292.1 CDS flk NC_012759.1 2321777 2322772 D in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 2321777..2322772 Escherichia coli BW2952 7953531 YP_002927293.1 CDS yfcJ NC_012759.1 2322769 2323947 R MG1655 equivalent: b2322; hypothetical protein complement(2322769..2323947) Escherichia coli BW2952 7954902 YP_002927294.1 CDS fabB NC_012759.1 2324212 2325432 R FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase complement(2324212..2325432) Escherichia coli BW2952 7955661 YP_002927295.1 CDS mnmC NC_012759.1 2325591 2327597 D catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 2325591..2327597 Escherichia coli BW2952 7952318 YP_002927296.1 CDS yfcL NC_012759.1 2327718 2327996 R MG1655 equivalent: b2325; hypothetical protein complement(2327718..2327996) Escherichia coli BW2952 7953652 YP_002927297.1 CDS yfcM NC_012759.1 2328030 2328578 R MG1655 equivalent: b2326; hypothetical protein complement(2328030..2328578) Escherichia coli BW2952 7955388 YP_002927298.1 CDS yfcA NC_012759.1 2328578 2329387 R MG1655 equivalent: b2327; hypothetical protein complement(2328578..2329387) Escherichia coli BW2952 7952839 YP_002927299.1 CDS mepA NC_012759.1 2329387 2330211 R D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase complement(2329387..2330211) Escherichia coli BW2952 7952678 YP_002927300.1 CDS aroC NC_012759.1 2330215 2331300 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(2330215..2331300) Escherichia coli BW2952 7954320 YP_002927301.1 CDS prmB NC_012759.1 2331335 2332267 R involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(2331335..2332267) Escherichia coli BW2952 7952636 YP_002927302.1 CDS yfcN NC_012759.1 2332433 2332984 D MG1655 equivalent: b2331; hypothetical protein 2332433..2332984 Escherichia coli BW2952 7954332 YP_002927303.1 CDS yfcO NC_012759.1 2333055 2333876 R MG1655 equivalent: b2332; hypothetical protein complement(2333055..2333876) Escherichia coli BW2952 7952998 YP_002927304.1 CDS yfcP NC_012759.1 2333878 2334417 R MG1655 equivalent: b2333; putative fimbrial-like adhesin protein complement(2333878..2334417) Escherichia coli BW2952 7955389 YP_002927305.1 CDS yfcQ NC_012759.1 2334414 2334902 R MG1655 equivalent: b2334; putative fimbrial-like adhesin protein complement(2334414..2334902) Escherichia coli BW2952 7954888 YP_002927306.1 CDS yfcR NC_012759.1 2334899 2335411 R MG1655 equivalent: b2335; putative fimbrial-like adhesin protein complement(2334899..2335411) Escherichia coli BW2952 7954889 YP_002927307.1 CDS yfcS NC_012759.1 2335411 2336163 R MG1655 equivalent: b2336; putative periplasmic pilus chaperone complement(2335411..2336163) Escherichia coli BW2952 7954890 YP_002927308.1 CDS yfcV NC_012759.1 2338910 2339473 R MG1655 equivalent: b2339; putative fimbrial-like adhesin protein complement(2338910..2339473) Escherichia coli BW2952 7955306 YP_002927309.1 CDS sixA NC_012759.1 2340154 2340639 R MG1655 equivalent: b2340; phosphohistidine phosphatase complement(2340154..2340639) Escherichia coli BW2952 7954891 YP_002927310.1 CDS fadJ NC_012759.1 2340842 2342986 R multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha complement(2340842..2342986) Escherichia coli BW2952 7954539 YP_002927311.1 CDS fadI NC_012759.1 2342986 2344296 R FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase complement(2342986..2344296) Escherichia coli BW2952 7953679 YP_002927312.1 CDS yfcZ NC_012759.1 2344477 2344761 R MG1655 equivalent: b2343; hypothetical protein complement(2344477..2344761) Escherichia coli BW2952 7952550 YP_002927313.1 CDS fadL NC_012759.1 2345133 2346473 D MG1655 equivalent: b2344; long-chain fatty acid outer membrane transporter 2345133..2346473 Escherichia coli BW2952 7952840 YP_002927314.1 CDS yfdF NC_012759.1 2346839 2347897 D MG1655 equivalent: b2345; hypothetical protein 2346839..2347897 Escherichia coli BW2952 7954163 YP_002927315.1 CDS vacJ NC_012759.1 2348079 2348834 R MG1655 equivalent: b2346; putative lipoprotein complement(2348079..2348834) Escherichia coli BW2952 7955496 YP_002927316.1 CDS yfdC NC_012759.1 2349128 2350060 D MG1655 equivalent: b2347; putative inner membrane protein 2349128..2350060 Escherichia coli BW2952 7955111 YP_002927317.1 CDS intS NC_012759.1 2350372 2351529 D MG1655 equivalent: b2349; CPS-53 (KpLE1) prophage; putative prophage CPS-53 integrase 2350372..2351529 Escherichia coli BW2952 7952136 YP_002927318.1 CDS yfdG NC_012759.1 2351682 2352044 D MG1655 equivalent: b2350; CPS-53 (KpLE1) prophage; bactoprenol-linked glucose translocase (flippase) 2351682..2352044 Escherichia coli BW2952 7953147 YP_002927319.1 CDS yfdH NC_012759.1 2352041 2352961 D MG1655 equivalent: b2351; CPS-53 (KpLE1) prophage; bactoprenol glucosyl transferase 2352041..2352961 Escherichia coli BW2952 7953143 YP_002927320.1 CDS yfdI NC_012759.1 2352958 2354289 D MG1655 equivalent: b2352; CPS-53 (KpLE1) prophage; putative inner membrane protein 2352958..2354289 Escherichia coli BW2952 7953142 YP_002927321.1 CDS yfdK NC_012759.1 2354904 2355344 R MG1655 equivalent: b2354; CPS-53 (KpLE1) prophage protein complement(2354904..2355344) Escherichia coli BW2952 7953146 YP_002927322.1 CDS yfdN NC_012759.1 2356214 2356708 R MG1655 equivalent: b2357; CPS-53 (KpLE1) prophage protein complement(2356214..2356708) Escherichia coli BW2952 7953144 YP_002927323.1 CDS yfdP NC_012759.1 2357431 2357793 D MG1655 equivalent: b2359; CPS-53 (KpLE1) prophage protein 2357431..2357793 Escherichia coli BW2952 7953148 YP_002927324.1 CDS yfdQ NC_012759.1 2357859 2358683 D MG1655 equivalent: b2360; CPS-53 (KpLE1) prophage protein 2357859..2358683 Escherichia coli BW2952 7953149 YP_002927325.1 CDS yfdR NC_012759.1 2358811 2359347 D MG1655 equivalent: b2361; CPS-53 (KpLE1) prophage protein 2358811..2359347 Escherichia coli BW2952 7953150 YP_002927326.1 CDS yfdS NC_012759.1 2359338 2359700 D MG1655 equivalent: b2362; CPS-53 (KpLE1) prophage protein 2359338..2359700 Escherichia coli BW2952 7953145 YP_002927327.1 CDS yfdT NC_012759.1 2359700 2360005 D MG1655 equivalent: b2363; CPS-53 (KpLE1) prophage protein 2359700..2360005 Escherichia coli BW2952 7953151 YP_002927328.1 CDS torI NC_012759.1 2360137 2360337 D MG1655 equivalent: b4501; response regulator inhibitor for tor operon 2360137..2360337 Escherichia coli BW2952 7953152 YP_002927329.1 CDS dsdC NC_012759.1 2360521 2361456 R regulates the synthesis and expression of the dsdXA operon and dadA gene; DNA-binding transcriptional regulator DsdC complement(2360521..2361456) Escherichia coli BW2952 7952137 YP_002927330.1 CDS dsdX NC_012759.1 2361674 2363011 D member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; permease DsdX 2361674..2363011 Escherichia coli BW2952 7953407 YP_002927331.1 CDS dsdA NC_012759.1 2363029 2364357 D catalyzes the formation of pyruvate from serine; D-serine dehydratase 2363029..2364357 Escherichia coli BW2952 7955695 YP_002927332.1 CDS emrY NC_012759.1 2364465 2366003 R MG1655 equivalent: b2367; putative multidrug efflux system complement(2364465..2366003) Escherichia coli BW2952 7953497 YP_002927333.1 CDS emrK NC_012759.1 2366003 2367166 R MG1655 equivalent: b2368; EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein component complement(2366003..2367166) Escherichia coli BW2952 7955173 YP_002927334.1 CDS evgA NC_012759.1 2367582 2368196 D response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; DNA-binding transcriptional activator EvgA 2367582..2368196 Escherichia coli BW2952 7953515 YP_002927335.1 CDS evgS NC_012759.1 2368201 2371794 D MG1655 equivalent: b2370; hybrid sensory histidine kinase in two-component regulatory system with EvgA 2368201..2371794 Escherichia coli BW2952 7953353 YP_002927336.1 CDS yfdE NC_012759.1 2371850 2372995 R MG1655 equivalent: b2371; hypothetical protein complement(2371850..2372995) Escherichia coli BW2952 7953929 YP_002927337.1 CDS yfdV NC_012759.1 2373069 2374013 R member of the AEC family of auxin efflux transporters; unknown function; putative transporter YfdV complement(2373069..2374013) Escherichia coli BW2952 7954697 YP_002927338.1 CDS oxc NC_012759.1 2374083 2375777 R catalyzes the formation of formyl-CoA from oxalyl-CoA; putative oxalyl-CoA decarboxylase complement(2374083..2375777) Escherichia coli BW2952 7955662 YP_002927339.1 CDS frc NC_012759.1 2375831 2377081 R catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase complement(2375831..2377081) Escherichia coli BW2952 7955220 YP_002927340.1 CDS yfdX NC_012759.1 2377594 2378229 R MG1655 equivalent: b2375; hypothetical protein complement(2377594..2378229) Escherichia coli BW2952 7953629 YP_002927341.1 CDS ypdI NC_012759.1 2378525 2378800 D MG1655 equivalent: b2376; putative lipoprotein involved in colanic acid biosynthesis 2378525..2378800 Escherichia coli BW2952 7955390 YP_002927342.1 CDS yfdY NC_012759.1 2378877 2379119 R MG1655 equivalent: b2377; putative inner membrane protein complement(2378877..2379119) Escherichia coli BW2952 7955121 YP_002927343.1 CDS lpxP NC_012759.1 2379472 2380392 D Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 2379472..2380392 Escherichia coli BW2952 7955002 YP_002927344.1 CDS yfdZ NC_012759.1 2380884 2382122 R MG1655 equivalent: b2379; aminotransferase complement(2380884..2382122) Escherichia coli BW2952 7954461 YP_002927345.1 CDS ypdA NC_012759.1 2382498 2384195 D MG1655 equivalent: b2380; putative sensory kinase in two-component system with YpdB 2382498..2384195 Escherichia coli BW2952 7955759 YP_002927346.1 CDS ypdB NC_012759.1 2384210 2384944 D MG1655 equivalent: b2381; putative response regulator in two-component system withYpdA 2384210..2384944 Escherichia coli BW2952 7955589 YP_002927347.1 CDS ypdC NC_012759.1 2384957 2385814 D MG1655 equivalent: b2382; putative DNA-binding protein 2384957..2385814 Escherichia coli BW2952 7955568 YP_002927348.1 CDS fryA NC_012759.1 2385817 2388312 R MG1655 equivalent: b2383; fused putative PTS enzymes: Hpr component/enzyme I component/enzyme IIA component complement(2385817..2388312) Escherichia coli BW2952 7954738 YP_002927349.1 CDS ypdE NC_012759.1 2388337 2389374 R metalloprotein; exoaminopeptidase complement(2388337..2389374) Escherichia coli BW2952 7953723 YP_002927350.1 CDS ypdF NC_012759.1 2389374 2390459 R Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase complement(2389374..2390459) Escherichia coli BW2952 7955275 YP_002927351.1 CDS fryC NC_012759.1 2390474 2391721 R MG1655 equivalent: b2386; putative enzyme IIC component of PTS complement(2390474..2391721) Escherichia coli BW2952 7955276 YP_002927352.1 CDS fryB NC_012759.1 2391743 2392069 R MG1655 equivalent: b2387; putative enzyme IIB component of PTS complement(2391743..2392069) Escherichia coli BW2952 7954856 YP_002927353.1 CDS glk NC_012759.1 2392288 2393253 R catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase complement(2392288..2393253) Escherichia coli BW2952 7954852 YP_002927354.1 CDS yfeO NC_012759.1 2393457 2394713 D MG1655 equivalent: b2389; hypothetical protein 2393457..2394713 Escherichia coli BW2952 7953796 YP_002927355.1 CDS ypeC NC_012759.1 2394828 2395154 D MG1655 equivalent: b2390; hypothetical protein 2394828..2395154 Escherichia coli BW2952 7955086 YP_002927356.1 CDS mntH NC_012759.1 2395295 2396533 R MG1655 equivalent: b2392; manganese transport protein MntH complement(2395295..2396533) Escherichia coli BW2952 7952999 YP_002927357.1 CDS nupC NC_012759.1 2396869 2398071 D MG1655 equivalent: b2393; nucleoside (except guanosine) transporter 2396869..2398071 Escherichia coli BW2952 7954210 YP_002927358.1 CDS insL NC_012759.1 2398158 2399270 D MG1655 equivalent: b2394; IS186/IS421 transposase 2398158..2399270 Escherichia coli BW2952 7954409 YP_002927359.1 CDS yfeA NC_012759.1 2399470 2401659 R MG1655 equivalent: b2395; putative diguanylate cyclase complement(2399470..2401659) Escherichia coli BW2952 7954027 YP_002927360.1 CDS yfeC NC_012759.1 2402294 2402638 D MG1655 equivalent: b2398; putative DNA-binding transcriptional regulator 2402294..2402638 Escherichia coli BW2952 7952059 YP_002927361.1 CDS yfeD NC_012759.1 2402661 2403032 D MG1655 equivalent: b2399; putative DNA-binding transcriptional regulator 2402661..2403032 Escherichia coli BW2952 7954804 YP_002927362.1 CDS gltX NC_012759.1 2403084 2404499 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(2403084..2404499) Escherichia coli BW2952 7954805 YP_002927363.1 CDS xapR NC_012759.1 2405420 2406304 R MG1655 equivalent: b2405; DNA-binding transcriptional activator XapR complement(2405420..2406304) Escherichia coli BW2952 7952141 YP_002927364.1 CDS xapB NC_012759.1 2406556 2407812 R MG1655 equivalent: b2406; xanthosine transporter complement(2406556..2407812) Escherichia coli BW2952 7953368 YP_002927365.1 CDS xapA NC_012759.1 2407872 2408705 R catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase complement(2407872..2408705) Escherichia coli BW2952 7956279 YP_002927366.1 CDS yfeN NC_012759.1 2408954 2409718 D MG1655 equivalent: b2408; hypothetical protein 2408954..2409718 Escherichia coli BW2952 7955823 YP_002927367.1 CDS yfeR NC_012759.1 2409757 2410683 R MG1655 equivalent: b2409; putative DNA-binding transcriptional regulator complement(2409757..2410683) Escherichia coli BW2952 7952750 YP_002927368.1 CDS yfeH NC_012759.1 2410773 2411771 D MG1655 equivalent: b2410; putative inner membrane protein 2410773..2411771 Escherichia coli BW2952 7954769 YP_002927369.1 CDS ypeB NC_012759.1 2411768 2411986 R MG1655 equivalent: b4546; hypothetical protein complement(2411768..2411986) Escherichia coli BW2952 7955054 YP_002927370.1 CDS ligA NC_012759.1 2411988 2414003 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(2411988..2414003) Escherichia coli BW2952 7955434 YP_002927371.1 CDS zipA NC_012759.1 2414074 2415060 R interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA complement(2414074..2415060) Escherichia coli BW2952 7953311 YP_002927372.1 CDS cysZ NC_012759.1 2415290 2416051 D putative role in sulfur assimilation; putative sulfate transport protein CysZ 2415290..2416051 Escherichia coli BW2952 7952617 YP_002927373.1 CDS cysK NC_012759.1 2416236 2417207 D CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 2416236..2417207 Escherichia coli BW2952 7955055 YP_002927374.1 CDS ptsH NC_012759.1 2417591 2417848 D MG1655 equivalent: b2415; PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr 2417591..2417848 Escherichia coli BW2952 7953184 YP_002927375.1 CDS ptsI NC_012759.1 2417893 2419620 D Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 2417893..2419620 Escherichia coli BW2952 7954541 YP_002927376.1 CDS crr NC_012759.1 2419661 2420170 D functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter 2419661..2420170 Escherichia coli BW2952 7954471 YP_002927377.1 CDS pdxK NC_012759.1 2420213 2421064 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase complement(2420213..2421064) Escherichia coli BW2952 7953812 YP_002927378.1 CDS yfeK NC_012759.1 2421169 2421543 D MG1655 equivalent: b2419; hypothetical protein 2421169..2421543 Escherichia coli BW2952 7955839 YP_002927379.1 CDS yfeS NC_012759.1 2421576 2422310 D MG1655 equivalent: b2420; hypothetical protein 2421576..2422310 Escherichia coli BW2952 7955497 YP_002927380.1 CDS cysM NC_012759.1 2422499 2423410 R catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B complement(2422499..2423410) Escherichia coli BW2952 7953000 YP_002927381.1 CDS cysA NC_012759.1 2423544 2424641 R MG1655 equivalent: b2422; sulfate/thiosulfate transporter subunit complement(2423544..2424641) Escherichia coli BW2952 7953185 YP_002927382.1 CDS cysW NC_012759.1 2424631 2425506 R Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit complement(2424631..2425506) Escherichia coli BW2952 7956091 YP_002927383.1 CDS cysU NC_012759.1 2425506 2426339 R MG1655 equivalent: b2424; sulfate/thiosulfate transporter subunit complement(2425506..2426339) Escherichia coli BW2952 7956092 YP_002927384.1 CDS cysP NC_012759.1 2426339 2427355 R MG1655 equivalent: b2425; thiosulfate transporter subunit complement(2426339..2427355) Escherichia coli BW2952 7956093 YP_002927385.1 CDS ucpA NC_012759.1 2427659 2428450 R MG1655 equivalent: b2426; short chain dehydrogenase complement(2427659..2428450) Escherichia coli BW2952 7956137 YP_002927386.1 CDS yfeT NC_012759.1 2428579 2429436 R MG1655 equivalent: b2427; putative DNA-binding transcriptional regulator complement(2428579..2429436) Escherichia coli BW2952 7955267 YP_002927387.1 CDS murQ NC_012759.1 2429600 2430496 D catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 2429600..2430496 Escherichia coli BW2952 7954770 YP_002927388.1 CDS murP NC_012759.1 2430500 2431924 D belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunit IIBC 2430500..2431924 Escherichia coli BW2952 7955548 YP_002927389.1 CDS yfeW NC_012759.1 2431929 2433233 D MG1655 equivalent: b2430; hypothetical protein 2431929..2433233 Escherichia coli BW2952 7953726 YP_002927390.1 CDS yfeX NC_012759.1 2433473 2434372 R MG1655 equivalent: b2431; hypothetical protein complement(2433473..2434372) Escherichia coli BW2952 7955299 YP_002927391.1 CDS yfeY NC_012759.1 2434468 2435043 R MG1655 equivalent: b2432; hypothetical protein complement(2434468..2435043) Escherichia coli BW2952 7952841 YP_002927392.1 CDS yfeZ NC_012759.1 2435104 2435553 R MG1655 equivalent: b2433; putative inner membrane protein complement(2435104..2435553) Escherichia coli BW2952 7955391 YP_002927393.1 CDS ypeA NC_012759.1 2435540 2435965 R MG1655 equivalent: b2434; putative acetyltransferase complement(2435540..2435965) Escherichia coli BW2952 7955003 YP_002927394.1 CDS amiA NC_012759.1 2436179 2437048 D MG1655 equivalent: b2435; N-acetylmuramoyl-l-alanine amidase I 2436179..2437048 Escherichia coli BW2952 7954617 YP_002927395.1 CDS hemF NC_012759.1 2437052 2437951 D catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 2437052..2437951 Escherichia coli BW2952 7954344 YP_002927396.1 CDS eutR NC_012759.1 2437957 2439009 R activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR complement(2437957..2439009) Escherichia coli BW2952 7953101 YP_002927397.1 CDS eutK NC_012759.1 2439055 2439555 R MG1655 equivalent: b2438; putative carboxysome structural protein with putative role in ethanolamine utilization complement(2439055..2439555) Escherichia coli BW2952 7954771 YP_002927398.1 CDS eutL NC_012759.1 2439568 2440227 R MG1655 equivalent: b2439; putative carboxysome structural protein with putative role in ethanolamine utilization complement(2439568..2440227) Escherichia coli BW2952 7954678 YP_002927399.1 CDS eutC NC_012759.1 2440237 2441124 R catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit complement(2440237..2441124) Escherichia coli BW2952 7954679 YP_002927400.1 CDS eutB NC_012759.1 2441145 2442506 R MG1655 equivalent: b2441; ethanolamine ammonia-lyase, large subunit, heavy chain complement(2441145..2442506) Escherichia coli BW2952 7953535 YP_002927401.1 CDS intZ NC_012759.1 2442685 2443893 D MG1655 equivalent: b2442; CPZ-55 prophage; putative integrase 2442685..2443893 Escherichia coli BW2952 7953534 YP_002927402.1 CDS yffL NC_012759.1 2444084 2444725 D MG1655 equivalent: b2443; CPZ-55 prophage protein 2444084..2444725 Escherichia coli BW2952 7953153 YP_002927403.1 CDS yffM NC_012759.1 2445195 2445440 D MG1655 equivalent: b2444; CPZ-55 prophage protein 2445195..2445440 Escherichia coli BW2952 7953154 YP_002927404.1 CDS yffN NC_012759.1 2445452 2445820 D MG1655 equivalent: b2445; CPZ-55 prophage protein 2445452..2445820 Escherichia coli BW2952 7953155 YP_002927405.1 CDS yffO NC_012759.1 2445938 2446354 D MG1655 equivalent: b2446; CPZ-55 prophage protein 2445938..2446354 Escherichia coli BW2952 7953156 YP_002927406.1 CDS yffP NC_012759.1 2446351 2446944 D MG1655 equivalent: b2447; CPZ-55 prophage protein 2446351..2446944 Escherichia coli BW2952 7953157 YP_002927407.1 CDS yffQ NC_012759.1 2447419 2447796 D MG1655 equivalent: b2448; CPZ-55 prophage protein 2447419..2447796 Escherichia coli BW2952 7953158 YP_002927408.1 CDS yffR NC_012759.1 2447807 2448199 D MG1655 equivalent: b2449; CPZ-55 prophage protein 2447807..2448199 Escherichia coli BW2952 7953159 YP_002927409.1 CDS yffS NC_012759.1 2448350 2449159 D MG1655 equivalent: b2450; CPZ-55 prophage protein 2448350..2449159 Escherichia coli BW2952 7953160 YP_002927410.1 CDS eutA NC_012759.1 2449308 2450711 R ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase complement(2449308..2450711) Escherichia coli BW2952 7953161 YP_002927411.1 CDS eutH NC_012759.1 2450708 2451934 R MG1655 equivalent: b2452; putative inner membrane protein complement(2450708..2451934) Escherichia coli BW2952 7955914 YP_002927412.1 CDS eutG NC_012759.1 2452151 2453338 R MG1655 equivalent: b2453; putative alcohol dehydrogenase in ethanolamine utilization complement(2452151..2453338) Escherichia coli BW2952 7955004 YP_002927413.1 CDS eutJ NC_012759.1 2453328 2454164 R MG1655 equivalent: b2454; putative chaperonin, ethanolamine utilization protein complement(2453328..2454164) Escherichia coli BW2952 7954625 YP_002927414.1 CDS eutE NC_012759.1 2454175 2455578 R MG1655 equivalent: b2455; putative aldehyde dehydrogenase, ethanolamine utilization protein complement(2454175..2455578) Escherichia coli BW2952 7954691 YP_002927415.1 CDS eutN NC_012759.1 2455590 2455877 R MG1655 equivalent: b2456; putative carboxysome structural protein, ethanolamine utilization protein complement(2455590..2455877) Escherichia coli BW2952 7954628 YP_002927416.1 CDS eutM NC_012759.1 2455984 2456277 R MG1655 equivalent: b2457; putative carboxysome structural protein, ethanolamine utilization protein complement(2455984..2456277) Escherichia coli BW2952 7954680 YP_002927417.1 CDS eutD NC_012759.1 2456316 2457332 R in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase complement(2456316..2457332) Escherichia coli BW2952 7954681 YP_002927418.1 CDS eutT NC_012759.1 2457329 2458132 R MG1655 equivalent: b2459; putative cobalamin adenosyltransferase in ethanolamine utilization complement(2457329..2458132) Escherichia coli BW2952 7955320 YP_002927419.1 CDS eutQ NC_012759.1 2458129 2458830 R MG1655 equivalent: b2460; hypothetical protein complement(2458129..2458830) Escherichia coli BW2952 7954698 YP_002927420.1 CDS eutP NC_012759.1 2458805 2459284 R MG1655 equivalent: b2461; hypothetical protein complement(2458805..2459284) Escherichia coli BW2952 7952842 YP_002927421.1 CDS eutS NC_012759.1 2459297 2459632 R MG1655 equivalent: b2462; putative carboxysome structural protein with putative role in ethanol utilization complement(2459297..2459632) Escherichia coli BW2952 7953085 YP_002927422.1 CDS maeB NC_012759.1 2459925 2462204 R NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme complement(2459925..2462204) Escherichia coli BW2952 7954677 YP_002927423.1 CDS talA NC_012759.1 2462493 2463443 D MG1655 equivalent: b2464; transaldolase A 2462493..2463443 Escherichia coli BW2952 7953695 YP_002927424.1 CDS tktB NC_012759.1 2463463 2465466 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2463463..2465466 Escherichia coli BW2952 7956164 YP_002927425.1 CDS ypfG NC_012759.1 2465561 2466604 R MG1655 equivalent: b2466; hypothetical protein complement(2465561..2466604) Escherichia coli BW2952 7956175 YP_002927426.1 CDS nudK NC_012759.1 2466730 2467305 R MG1655 equivalent: b2467; putative NUDIX hydrolase complement(2466730..2467305) Escherichia coli BW2952 7955392 YP_002927427.1 CDS aegA NC_012759.1 2467373 2469352 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); putative oxidoreductase Fe-S binding subunit complement(2467373..2469352) Escherichia coli BW2952 7955189 YP_002927428.1 CDS narQ NC_012759.1 2469558 2471258 D MG1655 equivalent: b2469; nitrate/nitrite sensor protein NarQ 2469558..2471258 Escherichia coli BW2952 7953720 YP_002927429.1 CDS acrD NC_012759.1 2471422 2474535 D MG1655 equivalent: b2470; aminoglycoside/multidrug efflux system 2471422..2474535 Escherichia coli BW2952 7956021 YP_002927431.1 CDS yffB NC_012759.1 2475074 2475430 D MG1655 equivalent: b2471; hypothetical protein 2475074..2475430 Escherichia coli BW2952 7953969 YP_002927432.1 CDS dapE NC_012759.1 2475434 2476561 D dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2475434..2476561 Escherichia coli BW2952 7953001 YP_002927433.1 CDS ypfN NC_012759.1 2476589 2476789 D MG1655 equivalent: b4547; hypothetical protein 2476589..2476789 Escherichia coli BW2952 7954407 YP_002927434.1 CDS ypfH NC_012759.1 2476899 2477597 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YpfH complement(2476899..2477597) Escherichia coli BW2952 7955535 YP_002927435.1 CDS ypfI NC_012759.1 2477671 2479686 R MG1655 equivalent: b2474; putative hydrolase complement(2477671..2479686) Escherichia coli BW2952 7954957 YP_002927436.1 CDS ypfJ NC_012759.1 2479701 2480564 R MG1655 equivalent: b2475; hypothetical protein complement(2479701..2480564) Escherichia coli BW2952 7954958 YP_002927437.1 CDS purC NC_012759.1 2480732 2481445 R catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase complement(2480732..2481445) Escherichia coli BW2952 7952843 YP_002927438.1 CDS bamC NC_012759.1 2481658 2482692 R MG1655 equivalent: b2477; lipoprotein complement(2481658..2482692) Escherichia coli BW2952 7954549 YP_002927439.1 CDS dapA NC_012759.1 2482709 2483587 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(2482709..2483587) Escherichia coli BW2952 7954156 YP_002927440.1 CDS gcvR NC_012759.1 2483733 2484305 D negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 2483733..2484305 Escherichia coli BW2952 7953250 YP_002927441.1 CDS bcp NC_012759.1 2484305 2484775 D bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 2484305..2484775 Escherichia coli BW2952 7953480 YP_002927442.1 CDS hyfA NC_012759.1 2485028 2485645 D MG1655 equivalent: b2481; hydrogenase 4, 4Fe-4S subunit 2485028..2485645 Escherichia coli BW2952 7956133 YP_002927443.1 CDS hyfB NC_012759.1 2485645 2487663 D MG1655 equivalent: b2482; hydrogenase 4 subunit B 2485645..2487663 Escherichia coli BW2952 7953948 YP_002927444.1 CDS hyfC NC_012759.1 2487674 2488621 D MG1655 equivalent: b2483; hydrogenase 4, membrane subunit 2487674..2488621 Escherichia coli BW2952 7953951 YP_002927445.1 CDS hyfD NC_012759.1 2488638 2490077 D MG1655 equivalent: b2484; hydrogenase 4 subunit D 2488638..2490077 Escherichia coli BW2952 7953952 YP_002927446.1 CDS hyfE NC_012759.1 2490089 2490739 D interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide; hydrogenase 4 membrane subunit 2490089..2490739 Escherichia coli BW2952 7953953 YP_002927447.1 CDS hyfF NC_012759.1 2490744 2492324 D MG1655 equivalent: b2486; hydrogenase 4 subunit F 2490744..2492324 Escherichia coli BW2952 7953954 YP_002927448.1 CDS hyfG NC_012759.1 2492314 2493981 D MG1655 equivalent: b2487; hydrogenase 4 subunit 2492314..2493981 Escherichia coli BW2952 7953955 YP_002927449.1 CDS hyfH NC_012759.1 2493991 2494536 D probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far; hydrogenase 4 subunit H 2493991..2494536 Escherichia coli BW2952 7953956 YP_002927450.1 CDS hyfI NC_012759.1 2494533 2495291 D MG1655 equivalent: b2489; hydrogenase 4, Fe-S subunit 2494533..2495291 Escherichia coli BW2952 7953949 YP_002927451.1 CDS hyfJ NC_012759.1 2495284 2495697 D MG1655 equivalent: b2490; putative processing element hydrogenase 4 2495284..2495697 Escherichia coli BW2952 7953950 YP_002927452.1 CDS hyfR NC_012759.1 2495727 2497739 D MG1655 equivalent: b2491; DNA-binding transcriptional activator, formate sensing 2495727..2497739 Escherichia coli BW2952 7955329 YP_002927453.1 CDS focB NC_012759.1 2497761 2498609 D inner membrane protein presumed to act as a formate transporter; member of the hyf operon; putative formate transporter 2497761..2498609 Escherichia coli BW2952 7953396 YP_002927454.1 CDS yfgO NC_012759.1 2498647 2499708 R MG1655 equivalent: b2493; putative inner membrane protein complement(2498647..2499708) Escherichia coli BW2952 7954911 YP_002927455.1 CDS yfgC NC_012759.1 2499921 2501384 D MG1655 equivalent: b2494; putative peptidase 2499921..2501384 Escherichia coli BW2952 7955005 YP_002927456.1 CDS yfgD NC_012759.1 2501405 2501764 D MG1655 equivalent: b2495; putative oxidoreductase 2501405..2501764 Escherichia coli BW2952 7955283 YP_002927457.1 CDS hda NC_012759.1 2501902 2502648 R controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor complement(2501902..2502648) Escherichia coli BW2952 7955236 YP_002927458.1 CDS uraA NC_012759.1 2502698 2503987 R MG1655 equivalent: b2497; uracil transporter complement(2502698..2503987) Escherichia coli BW2952 7952526 YP_002927459.1 CDS upp NC_012759.1 2504073 2504699 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(2504073..2504699) Escherichia coli BW2952 7956257 YP_002927460.1 CDS purM NC_012759.1 2505024 2506061 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 2505024..2506061 Escherichia coli BW2952 7956256 YP_002927461.1 CDS purN NC_012759.1 2506061 2506699 D glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 2506061..2506699 Escherichia coli BW2952 7954548 YP_002927462.1 CDS ppk NC_012759.1 2506871 2508937 D catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 2506871..2508937 Escherichia coli BW2952 7954551 YP_002927463.1 CDS ppx NC_012759.1 2508942 2510483 D MG1655 equivalent: b2502; exopolyphosphatase 2508942..2510483 Escherichia coli BW2952 7954569 YP_002927464.1 CDS yfgF NC_012759.1 2510522 2512765 R MG1655 equivalent: b2503; putative inner membrane protein complement(2510522..2512765) Escherichia coli BW2952 7953548 YP_002927465.1 CDS yfgG NC_012759.1 2513117 2513308 D MG1655 equivalent: b2504; hypothetical protein 2513117..2513308 Escherichia coli BW2952 7955006 YP_002927466.1 CDS yfgH NC_012759.1 2513619 2514137 D MG1655 equivalent: b2505; putative outer membrane lipoprotein 2513619..2514137 Escherichia coli BW2952 7955498 YP_002927467.1 CDS yfgI NC_012759.1 2514153 2514692 D MG1655 equivalent: b2506; hypothetical protein 2514153..2514692 Escherichia coli BW2952 7955202 YP_002927468.1 CDS guaA NC_012759.1 2514785 2516362 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(2514785..2516362) Escherichia coli BW2952 7953002 YP_002927469.1 CDS guaB NC_012759.1 2516431 2517897 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(2516431..2517897) Escherichia coli BW2952 7953873 YP_002927470.1 CDS xseA NC_012759.1 2518059 2519429 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 2518059..2519429 Escherichia coli BW2952 7953993 YP_002927471.1 CDS yfgJ NC_012759.1 2519426 2519641 R MG1655 equivalent: b2510; hypothetical protein complement(2519426..2519641) Escherichia coli BW2952 7953545 YP_002927472.1 CDS engA NC_012759.1 2519711 2521183 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(2519711..2521183) Escherichia coli BW2952 7955393 YP_002927473.1 CDS bamB NC_012759.1 2521301 2522479 R with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL complement(2521301..2522479) Escherichia coli BW2952 7954942 YP_002927474.1 CDS yfgM NC_012759.1 2522490 2523110 R MG1655 equivalent: b2513; hypothetical protein complement(2522490..2523110) Escherichia coli BW2952 7955781 YP_002927475.1 CDS hisS NC_012759.1 2523128 2524402 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(2523128..2524402) Escherichia coli BW2952 7952844 YP_002927476.1 CDS ispG NC_012759.1 2524513 2525631 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(2524513..2525631) Escherichia coli BW2952 7953914 YP_002927477.1 CDS yfgA NC_012759.1 2525658 2526671 R MG1655 equivalent: b2516; cytoskeletal protein RodZ complement(2525658..2526671) Escherichia coli BW2952 7952230 YP_002927478.1 CDS rlmN NC_012759.1 2526956 2528110 R 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N complement(2526956..2528110) Escherichia coli BW2952 7952845 YP_002927479.1 CDS ndk NC_012759.1 2528260 2528691 R catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase complement(2528260..2528691) Escherichia coli BW2952 7954842 YP_002927480.1 CDS pbpC NC_012759.1 2528840 2531152 R penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C complement(2528840..2531152) Escherichia coli BW2952 7954318 YP_002927481.1 CDS yfhM NC_012759.1 2531153 2536114 R MG1655 equivalent: b2520; hypothetical protein complement(2531153..2536114) Escherichia coli BW2952 7953747 YP_002927482.1 CDS sseA NC_012759.1 2536321 2537166 D catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 2536321..2537166 Escherichia coli BW2952 7952846 YP_002927483.1 CDS sseB NC_012759.1 2537984 2538760 R enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB complement(2537984..2538760) Escherichia coli BW2952 7952187 YP_002927484.1 CDS pepB NC_012759.1 2538902 2540185 R catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B complement(2538902..2540185) Escherichia coli BW2952 7955948 YP_002927485.1 CDS iscX NC_012759.1 2540363 2540563 R MG1655 equivalent: b2524; hypothetical protein complement(2540363..2540563) Escherichia coli BW2952 7952471 YP_002927486.1 CDS fdx NC_012759.1 2540575 2540910 R MG1655 equivalent: b2525; [2Fe-2S] ferredoxin complement(2540575..2540910) Escherichia coli BW2952 7952847 YP_002927487.1 CDS hscA NC_012759.1 2540912 2542762 R involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA complement(2540912..2542762) Escherichia coli BW2952 7952218 YP_002927488.1 CDS hscB NC_012759.1 2542779 2543294 R J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB complement(2542779..2543294) Escherichia coli BW2952 7953490 YP_002927489.1 CDS iscA NC_012759.1 2543390 2543713 R forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein complement(2543390..2543713) Escherichia coli BW2952 7953488 YP_002927490.1 CDS iscU NC_012759.1 2543730 2544116 R MG1655 equivalent: b2529; scaffold protein complement(2543730..2544116) Escherichia coli BW2952 7953575 YP_002927491.1 CDS iscS NC_012759.1 2544144 2545358 R catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase complement(2544144..2545358) Escherichia coli BW2952 7956001 YP_002927492.1 CDS iscR NC_012759.1 2545470 2545958 R regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR complement(2545470..2545958) Escherichia coli BW2952 7953182 YP_002927493.1 CDS trmJ NC_012759.1 2546410 2547150 R MG1655 equivalent: b2532; putative methyltransferase complement(2546410..2547150) Escherichia coli BW2952 7953454 YP_002927494.1 CDS suhB NC_012759.1 2547269 2548072 D MG1655 equivalent: b2533; inositol monophosphatase 2547269..2548072 Escherichia coli BW2952 7955153 YP_002927495.1 CDS yfhR NC_012759.1 2548190 2549071 D MG1655 equivalent: b2534; putative peptidase 2548190..2549071 Escherichia coli BW2952 7954001 YP_002927496.1 CDS csiE NC_012759.1 2549262 2550542 D MG1655 equivalent: b2535; stationary phase inducible protein CsiE 2549262..2550542 Escherichia coli BW2952 7955284 YP_002927497.1 CDS hcaT NC_012759.1 2550534 2551673 R putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; putative 3-phenylpropionic acid transporter complement(2550534..2551673) Escherichia coli BW2952 7956066 YP_002927498.1 CDS hcaR NC_012759.1 2551833 2552723 R activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional regulator HcaR complement(2551833..2552723) Escherichia coli BW2952 7954589 YP_002927499.1 CDS hcaE NC_012759.1 2552859 2554220 D MG1655 equivalent: b2538; 3-phenylpropionate dioxygenase, large (alpha) subunit 2552859..2554220 Escherichia coli BW2952 7953387 YP_002927500.1 CDS hcaF NC_012759.1 2554217 2554735 D MG1655 equivalent: b2539; 3-phenylpropionate dioxygenase subunit beta 2554217..2554735 Escherichia coli BW2952 7952321 YP_002927501.1 CDS hcaC NC_012759.1 2554735 2555055 D MG1655 equivalent: b2540; 3-phenylpropionate dioxygenase ferredoxin subunit 2554735..2555055 Escherichia coli BW2952 7952323 YP_002927502.1 CDS hcaB NC_012759.1 2555052 2555864 D Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate; 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase 2555052..2555864 Escherichia coli BW2952 7952322 YP_002927503.1 CDS hcaD NC_012759.1 2555874 2557076 D MG1655 equivalent: b2542; phenylpropionate dioxygenase ferredoxin reductase subunit 2555874..2557076 Escherichia coli BW2952 7952234 YP_002927504.1 CDS yphA NC_012759.1 2557173 2557595 D MG1655 equivalent: b2543; putative inner membrane protein 2557173..2557595 Escherichia coli BW2952 7954512 YP_002927505.1 CDS yphB NC_012759.1 2557643 2558515 R MG1655 equivalent: b2544; hypothetical protein complement(2557643..2558515) Escherichia coli BW2952 7955056 YP_002927506.1 CDS yphC NC_012759.1 2558527 2559588 R MG1655 equivalent: b2545; putative oxidoreductase, Zn-dependent and NAD(P)-binding complement(2558527..2559588) Escherichia coli BW2952 7952848 YP_002927507.1 CDS yphD NC_012759.1 2559654 2560652 R MG1655 equivalent: b2546; putative sugar transporter subunit: membrane component of ABC superfamily complement(2559654..2560652) Escherichia coli BW2952 7955261 YP_002927508.1 CDS yphE NC_012759.1 2560677 2562188 R MG1655 equivalent: b2547; fused putative sugar transporter subunits of ABC superfamily: ATP-binding components complement(2560677..2562188) Escherichia coli BW2952 7955606 YP_002927509.1 CDS yphF NC_012759.1 2562211 2563194 R MG1655 equivalent: b2548; putative sugar transporter subunit: periplasmic-binding component of ABC superfamily complement(2562211..2563194) Escherichia coli BW2952 7953728 YP_002927510.1 CDS yphG NC_012759.1 2563291 2566572 R MG1655 equivalent: b2549; hypothetical protein complement(2563291..2566572) Escherichia coli BW2952 7955609 YP_002927511.1 CDS yphH NC_012759.1 2566690 2567883 D MG1655 equivalent: b2550; putative DNA-binding transcriptional regulator 2566690..2567883 Escherichia coli BW2952 7952849 YP_002927512.1 CDS glyA NC_012759.1 2568081 2569334 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(2568081..2569334) Escherichia coli BW2952 7954806 YP_002927513.1 CDS hmp NC_012759.1 2569662 2570852 D flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 2569662..2570852 Escherichia coli BW2952 7956032 YP_002927514.1 CDS glnB NC_012759.1 2570897 2571235 R indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 complement(2570897..2571235) Escherichia coli BW2952 7953704 YP_002927515.1 CDS yfhA NC_012759.1 2571296 2572630 R MG1655 equivalent: b2554; putative DNA-binding response regulator in two-component system complement(2571296..2572630) Escherichia coli BW2952 7955936 YP_002927516.1 CDS yfhG NC_012759.1 2572620 2573333 R MG1655 equivalent: b2555; hypothetical protein complement(2572620..2573333) Escherichia coli BW2952 7954741 YP_002927517.1 CDS yfhK NC_012759.1 2573498 2574925 R MG1655 equivalent: b2556; putative sensory kinase in two-component system complement(2573498..2574925) Escherichia coli BW2952 7952850 YP_002927518.1 CDS purL NC_012759.1 2575483 2579370 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase complement(2575483..2579370) Escherichia coli BW2952 7952087 YP_002927519.1 CDS yfhD NC_012759.1 2579628 2581184 D YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; putative transglycosylase 2579628..2581184 Escherichia coli BW2952 7954550 YP_002927520.1 CDS tadA NC_012759.1 2581181 2581684 R MG1655 equivalent: b2559; tRNA-specific adenosine deaminase complement(2581181..2581684) Escherichia coli BW2952 7955297 YP_002927521.1 CDS yfhB NC_012759.1 2581742 2582377 R MG1655 equivalent: b2560; hypothetical protein complement(2581742..2582377) Escherichia coli BW2952 7956208 YP_002927522.1 CDS yfhH NC_012759.1 2582586 2583434 D MG1655 equivalent: b2561; putative DNA-binding transcriptional regulator 2582586..2583434 Escherichia coli BW2952 7952851 YP_002927523.1 CDS yfhL NC_012759.1 2583490 2583750 D MG1655 equivalent: b2562; putative 4Fe-4S cluster-containing protein 2583490..2583750 Escherichia coli BW2952 7954807 YP_002927524.1 CDS acpS NC_012759.1 2584445 2584825 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(2584445..2584825) Escherichia coli BW2952 7952188 YP_002927525.1 CDS pdxJ NC_012759.1 2584825 2585556 R involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase complement(2584825..2585556) Escherichia coli BW2952 7953917 YP_002927526.1 CDS recO NC_012759.1 2585568 2586296 R involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO complement(2585568..2586296) Escherichia coli BW2952 7955841 YP_002927527.1 CDS era NC_012759.1 2586308 2587213 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(2586308..2587213) Escherichia coli BW2952 7953773 YP_002927528.1 CDS rnc NC_012759.1 2587210 2587890 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(2587210..2587890) Escherichia coli BW2952 7954238 YP_002927529.1 CDS lepB NC_012759.1 2588162 2589136 R catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I complement(2588162..2589136) Escherichia coli BW2952 7955994 YP_002927530.1 CDS lepA NC_012759.1 2589152 2590951 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(2589152..2590951) Escherichia coli BW2952 7954123 YP_002927531.1 CDS rseC NC_012759.1 2591149 2591628 R involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC complement(2591149..2591628) Escherichia coli BW2952 7953880 YP_002927532.1 CDS rseB NC_012759.1 2591625 2592581 R periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE complement(2591625..2592581) Escherichia coli BW2952 7955995 YP_002927533.1 CDS rseA NC_012759.1 2592581 2593231 R MG1655 equivalent: b2572; anti-RNA polymerase sigma factor SigE complement(2592581..2593231) Escherichia coli BW2952 7952482 YP_002927534.1 CDS rpoE NC_012759.1 2593264 2593839 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE complement(2593264..2593839) Escherichia coli BW2952 7952483 YP_002927535.1 CDS nadB NC_012759.1 2594247 2595869 D catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 2594247..2595869 Escherichia coli BW2952 7955987 YP_002927536.1 CDS yfiC NC_012759.1 2595854 2596591 R MG1655 equivalent: b2575; putative S-adenosyl-L-methionine-dependent methyltransferase complement(2595854..2596591) Escherichia coli BW2952 7955887 YP_002927537.1 CDS srmB NC_012759.1 2596723 2598057 D facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 2596723..2598057 Escherichia coli BW2952 7955575 YP_002927538.1 CDS yfiE NC_012759.1 2598266 2599147 R MG1655 equivalent: b2577; putative DNA-binding transcriptional regulator complement(2598266..2599147) Escherichia coli BW2952 7952536 YP_002927539.1 CDS eamB NC_012759.1 2599250 2599837 D MG1655 equivalent: b2578; neutral amino-acid efflux protein 2599250..2599837 Escherichia coli BW2952 7954772 YP_002927540.1 CDS yfiD NC_012759.1 2599893 2600276 R stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA complement(2599893..2600276) Escherichia coli BW2952 7954375 YP_002927541.1 CDS ung NC_012759.1 2600581 2601270 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 2600581..2601270 Escherichia coli BW2952 7955850 YP_002927542.1 CDS yfiF NC_012759.1 2601318 2602355 R MG1655 equivalent: b2581; putative methyltransferase complement(2601318..2602355) Escherichia coli BW2952 7956258 YP_002927543.1 CDS trxC NC_012759.1 2602562 2602981 D MG1655 equivalent: b2582; thioredoxin 2 2602562..2602981 Escherichia coli BW2952 7955154 YP_002927544.1 CDS yfiP NC_012759.1 2603050 2603748 D MG1655 equivalent: b2583; hypothetical protein 2603050..2603748 Escherichia coli BW2952 7956135 YP_002927545.1 CDS yfiQ NC_012759.1 2603780 2606440 D MG1655 equivalent: b2584; fused putative acyl-CoA synthetase: NAD(P)-binding subunit/ATP-binding subunit 2603780..2606440 Escherichia coli BW2952 7953003 YP_002927546.1 CDS pssA NC_012759.1 2606554 2607909 D catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 2606554..2607909 Escherichia coli BW2952 7953709 YP_002927547.1 CDS yfiM NC_012759.1 2607955 2608278 D MG1655 equivalent: b2586; hypothetical protein 2607955..2608278 Escherichia coli BW2952 7954526 YP_002927548.1 CDS kgtP NC_012759.1 2608275 2609573 R MG1655 equivalent: b2587; alpha-ketoglutarate transporter complement(2608275..2609573) Escherichia coli BW2952 7955499 YP_002927549.1 CDS clpB NC_012759.1 2615434 2618007 R MG1655 equivalent: b2592; protein disaggregation chaperone complement(2615434..2618007) Escherichia coli BW2952 7952036 YP_002927550.1 CDS yfiH NC_012759.1 2618137 2618868 R MG1655 equivalent: b2593; hypothetical protein complement(2618137..2618868) Escherichia coli BW2952 7952089 YP_002927551.1 CDS rluD NC_012759.1 2618865 2619845 R responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D complement(2618865..2619845) Escherichia coli BW2952 7952852 YP_002927552.1 CDS bamD NC_012759.1 2619980 2620717 D with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 2619980..2620717 Escherichia coli BW2952 7952247 YP_002927553.1 CDS raiA NC_012759.1 2620988 2621329 D associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA 2620988..2621329 Escherichia coli BW2952 7955117 YP_002927555.1 CDS pheA NC_012759.1 2621579 2622739 D catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 2621579..2622739 Escherichia coli BW2952 7954505 YP_002927556.1 CDS tyrA NC_012759.1 2622782 2623903 R catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase complement(2622782..2623903) Escherichia coli BW2952 7953663 YP_002927557.1 CDS aroF NC_012759.1 2623914 2624984 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(2623914..2624984) Escherichia coli BW2952 7953664 YP_002927558.1 CDS yfiL NC_012759.1 2625194 2625559 D MG1655 equivalent: b2602; hypothetical protein 2625194..2625559 Escherichia coli BW2952 7952299 YP_002927559.1 CDS yfiR NC_012759.1 2625709 2626227 D MG1655 equivalent: b2603; hypothetical protein 2625709..2626227 Escherichia coli BW2952 7955500 YP_002927560.1 CDS yfiN NC_012759.1 2626217 2627443 D MG1655 equivalent: b2604; hypothetical protein 2626217..2627443 Escherichia coli BW2952 7955501 YP_002927561.1 CDS yfiB NC_012759.1 2627459 2627941 D MG1655 equivalent: b2605; putative outer membrane lipoprotein 2627459..2627941 Escherichia coli BW2952 7954732 YP_002927562.1 CDS rplS NC_012759.1 2628017 2628364 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(2628017..2628364) Escherichia coli BW2952 7955203 YP_002927563.1 CDS trmD NC_012759.1 2628406 2629173 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(2628406..2629173) Escherichia coli BW2952 7952346 YP_002927564.1 CDS rimM NC_012759.1 2629204 2629752 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(2629204..2629752) Escherichia coli BW2952 7956196 YP_002927565.1 CDS rpsP NC_012759.1 2629771 2630019 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(2629771..2630019) Escherichia coli BW2952 7952224 YP_002927566.1 CDS ffh NC_012759.1 2630268 2631629 R with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein complement(2630268..2631629) Escherichia coli BW2952 7952279 YP_002927567.1 CDS ypjD NC_012759.1 2631796 2632587 D MG1655 equivalent: b2611; putative inner membrane protein 2631796..2632587 Escherichia coli BW2952 7956045 YP_002927568.1 CDS yfjD NC_012759.1 2632632 2633894 D MG1655 equivalent: b4461; hypothetical protein 2632632..2633894 Escherichia coli BW2952 7955057 YP_002927569.1 CDS grpE NC_012759.1 2633949 2634542 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(2633949..2634542) Escherichia coli BW2952 7955074 YP_002927570.1 CDS ppnK NC_012759.1 2634665 2635543 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 2634665..2635543 Escherichia coli BW2952 7953892 YP_002927571.1 CDS recN NC_012759.1 2635629 2637290 D MG1655 equivalent: b2616; recombination and repair protein 2635629..2637290 Escherichia coli BW2952 7954348 YP_002927572.1 CDS smpA NC_012759.1 2637439 2637780 D MG1655 equivalent: b2617; hypothetical protein 2637439..2637780 Escherichia coli BW2952 7955915 YP_002927573.1 CDS yfjF NC_012759.1 2637842 2638132 R MG1655 equivalent: b2618; hypothetical protein complement(2637842..2638132) Escherichia coli BW2952 7956049 YP_002927574.1 CDS yfjG NC_012759.1 2638122 2638598 R MG1655 equivalent: b2619; hypothetical protein complement(2638122..2638598) Escherichia coli BW2952 7955394 YP_002927575.1 CDS smpB NC_012759.1 2638730 2639212 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 2638730..2639212 Escherichia coli BW2952 7952853 YP_002927576.1 CDS intA NC_012759.1 2639993 2641234 D CP4-57 prophage; integrase; integrase 2639993..2641234 Escherichia coli BW2952 7952203 YP_002927577.1 CDS yfjH NC_012759.1 2641478 2642434 R MG1655 equivalent: b2623; CP4-57 prophage protein complement(2641478..2642434) Escherichia coli BW2952 7953112 YP_002927578.1 CDS alpA NC_012759.1 2642478 2642690 D MG1655 equivalent: b2624; CP4-57 prophage; DNA-binding transcriptional activator 2642478..2642690 Escherichia coli BW2952 7953119 YP_002927579.1 CDS yfjI NC_012759.1 2642819 2644228 D MG1655 equivalent: b2625; CP4-57 prophage protein 2642819..2644228 Escherichia coli BW2952 7953111 YP_002927580.1 CDS yfjJ NC_012759.1 2644381 2645007 D MG1655 equivalent: b2626; CP4-57 prophage protein 2644381..2645007 Escherichia coli BW2952 7953122 YP_002927581.1 CDS yfjK NC_012759.1 2645185 2647374 R MG1655 equivalent: b2627; CP4-57 prophage protein complement(2645185..2647374) Escherichia coli BW2952 7953123 YP_002927582.1 CDS yfjL NC_012759.1 2647371 2648987 R MG1655 equivalent: b2628; CP4-57 prophage protein complement(2647371..2648987) Escherichia coli BW2952 7953110 YP_002927583.1 CDS yfjM NC_012759.1 2649347 2649610 R MG1655 equivalent: b2629; CP4-57 prophage protein complement(2649347..2649610) Escherichia coli BW2952 7953120 YP_002927584.1 CDS rnlA NC_012759.1 2649752 2650825 D MG1655 equivalent: b2630; CP4-57 prophage; RNase LS 2649752..2650825 Escherichia coli BW2952 7953121 YP_002927585.1 CDS yfjO NC_012759.1 2650818 2651189 D MG1655 equivalent: b2631; CP4-57 prophage protein 2650818..2651189 Escherichia coli BW2952 7953128 YP_002927586.1 CDS yfjP NC_012759.1 2651544 2652407 D MG1655 equivalent: b2632; CP4-57 prophage; putative GTP-binding protein 2651544..2652407 Escherichia coli BW2952 7953124 YP_002927587.1 CDS yfjQ NC_012759.1 2652499 2653320 D MG1655 equivalent: b2633; CP4-57 prophage protein 2652499..2653320 Escherichia coli BW2952 7953116 YP_002927588.1 CDS yfjR NC_012759.1 2653537 2654238 D MG1655 equivalent: b2634; CP4-57 prophage; putative DNA-binding transcriptional regulator 2653537..2654238 Escherichia coli BW2952 7953125 YP_002927589.1 CDS ypjK NC_012759.1 2654279 2654515 D MG1655 equivalent: b2635; CP4-57 prophage; putative inner membrane protein 2654279..2654515 Escherichia coli BW2952 7953115 YP_002927590.1 CDS yfjS NC_012759.1 2654515 2654958 D MG1655 equivalent: b2636; CP4-57 prophage protein 2654515..2654958 Escherichia coli BW2952 7953117 YP_002927591.1 CDS yfjT NC_012759.1 2654982 2655449 D MG1655 equivalent: b2637; CP4-57 prophage protein 2654982..2655449 Escherichia coli BW2952 7953126 YP_002927592.1 CDS yfjW NC_012759.1 2657152 2658855 D MG1655 equivalent: b2642; CP4-57 prophage; putative inner membrane protein 2657152..2658855 Escherichia coli BW2952 7953127 YP_002927593.1 CDS yfjX NC_012759.1 2659753 2660211 D MG1655 equivalent: b2643; CP4-57 prophage; putative antirestriction protein 2659753..2660211 Escherichia coli BW2952 7953118 YP_002927594.1 CDS yfjY NC_012759.1 2660220 2660702 D MG1655 equivalent: b2644; CP4-57 prophage; putative DNA repair protein 2660220..2660702 Escherichia coli BW2952 7953113 YP_002927595.1 CDS ypjJ NC_012759.1 2660711 2660911 D MG1655 equivalent: b4548; hypothetical protein 2660711..2660911 Escherichia coli BW2952 7953114 YP_002927596.1 CDS yfjZ NC_012759.1 2660949 2661266 D MG1655 equivalent: b2645; CP4-57 prophage; antitoxin of the YpjF-YfjZ toxin-antitoxin system 2660949..2661266 Escherichia coli BW2952 7955536 YP_002927597.1 CDS ypjF NC_012759.1 2661287 2661616 D MG1655 equivalent: b2646; CP4-57 prophage; toxin of the YpjF-YfjZ toxin-antitoxin system 2661287..2661616 Escherichia coli BW2952 7953109 YP_002927598.1 CDS ypjA NC_012759.1 2661980 2666560 R MG1655 equivalent: b2647; adhesin-like autotransporter complement(2661980..2666560) Escherichia coli BW2952 7952204 YP_002927599.1 CDS csiD NC_012759.1 2672819 2673796 D in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 2672819..2673796 Escherichia coli BW2952 7952061 YP_002927600.1 CDS ygaF NC_012759.1 2673816 2675084 D catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 2673816..2675084 Escherichia coli BW2952 7955502 YP_002927601.1 CDS gabD NC_012759.1 2675107 2676555 D catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I 2675107..2676555 Escherichia coli BW2952 7954846 YP_002927602.1 CDS gabT NC_012759.1 2676569 2677849 D catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 2676569..2677849 Escherichia coli BW2952 7956080 YP_002927603.1 CDS gabP NC_012759.1 2678087 2679487 D MG1655 equivalent: b2663; gamma-aminobutyrate transporter 2678087..2679487 Escherichia coli BW2952 7952330 YP_002927604.1 CDS csiR NC_012759.1 2679508 2680170 D regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 2679508..2680170 Escherichia coli BW2952 7953763 YP_002927605.1 CDS ygaU NC_012759.1 2680171 2680620 R MG1655 equivalent: b2665; LysM domain/BON superfamily protein complement(2680171..2680620) Escherichia coli BW2952 7953421 YP_002927606.1 CDS yqaE NC_012759.1 2680704 2680862 R MG1655 equivalent: b2666; hypothetical protein complement(2680704..2680862) Escherichia coli BW2952 7955395 YP_002927607.1 CDS ygaV NC_012759.1 2681045 2681344 D MG1655 equivalent: b2667; putative DNA-binding transcriptional regulator 2681045..2681344 Escherichia coli BW2952 7955140 YP_002927608.1 CDS ygaP NC_012759.1 2681354 2681878 D MG1655 equivalent: b2668; putative inner membrane protein with hydrolase activity 2681354..2681878 Escherichia coli BW2952 7954808 YP_002927609.1 CDS stpA NC_012759.1 2681925 2682329 R MG1655 equivalent: b2669; DNA binding protein complement(2681925..2682329) Escherichia coli BW2952 7955077 YP_002927610.1 CDS ygaW NC_012759.1 2682998 2683447 D MG1655 equivalent: b2670; putative inner membrane protein 2682998..2683447 Escherichia coli BW2952 7953299 YP_002927611.1 CDS ygaC NC_012759.1 2683484 2683828 R MG1655 equivalent: b2671; hypothetical protein complement(2683484..2683828) Escherichia coli BW2952 7955058 YP_002927612.1 CDS ygaM NC_012759.1 2683968 2684309 D MG1655 equivalent: b2672; hypothetical protein 2683968..2684309 Escherichia coli BW2952 7955396 YP_002927613.1 CDS nrdH NC_012759.1 2684557 2684802 D MG1655 equivalent: b2673; glutaredoxin-like protein 2684557..2684802 Escherichia coli BW2952 7955503 YP_002927614.1 CDS nrdI NC_012759.1 2684799 2685209 D in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 2684799..2685209 Escherichia coli BW2952 7953838 YP_002927615.1 CDS nrdE NC_012759.1 2685182 2687326 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2685182..2687326 Escherichia coli BW2952 7955811 YP_002927616.1 CDS nrdF NC_012759.1 2687336 2688295 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 2687336..2688295 Escherichia coli BW2952 7955969 YP_002927617.1 CDS proV NC_012759.1 2688649 2689851 D with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit 2688649..2689851 Escherichia coli BW2952 7955970 YP_002927618.1 CDS proW NC_012759.1 2689844 2690908 D with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 2689844..2690908 Escherichia coli BW2952 7953855 YP_002927619.1 CDS proX NC_012759.1 2690966 2691958 D with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 2690966..2691958 Escherichia coli BW2952 7953856 YP_002927620.1 CDS ygaZ NC_012759.1 2693451 2694188 D MG1655 equivalent: b2682; putative transporter 2693451..2694188 Escherichia coli BW2952 7953857 YP_002927621.1 CDS ygaH NC_012759.1 2694178 2694513 D MG1655 equivalent: b2683; hypothetical protein 2694178..2694513 Escherichia coli BW2952 7955696 YP_002927622.1 CDS mprA NC_012759.1 2694604 2695134 D DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 2694604..2695134 Escherichia coli BW2952 7955059 YP_002927623.1 CDS emrA NC_012759.1 2695261 2696433 D MG1655 equivalent: b2685; multidrug efflux system 2695261..2696433 Escherichia coli BW2952 7953473 YP_002927624.1 CDS emrB NC_012759.1 2696450 2697988 D MG1655 equivalent: b2686; multidrug efflux system protein 2696450..2697988 Escherichia coli BW2952 7954298 YP_002927625.1 CDS luxS NC_012759.1 2698052 2698567 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(2698052..2698567) Escherichia coli BW2952 7954303 YP_002927626.1 CDS gshA NC_012759.1 2698717 2700273 R involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase complement(2698717..2700273) Escherichia coli BW2952 7952189 YP_002927627.1 CDS yqaA NC_012759.1 2700346 2700774 R MG1655 equivalent: b2689; hypothetical protein complement(2700346..2700774) Escherichia coli BW2952 7953769 YP_002927628.1 CDS yqaB NC_012759.1 2700771 2701337 R YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase complement(2700771..2701337) Escherichia coli BW2952 7952679 YP_002927629.1 CDS csrA NC_012759.1 2702795 2702980 R affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator complement(2702795..2702980) Escherichia coli BW2952 7952066 YP_002927630.1 CDS alaS NC_012759.1 2703215 2705845 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(2703215..2705845) Escherichia coli BW2952 7954561 YP_002927631.1 CDS recX NC_012759.1 2705973 2706473 R binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX complement(2705973..2706473) Escherichia coli BW2952 7952440 YP_002927632.1 CDS recA NC_012759.1 2706542 2707603 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(2706542..2707603) Escherichia coli BW2952 7955934 YP_002927633.1 CDS ygaD NC_012759.1 2707683 2708180 R MG1655 equivalent: b2700; competence damage-inducible protein A complement(2707683..2708180) Escherichia coli BW2952 7953332 YP_002927634.1 CDS mltB NC_012759.1 2708325 2709410 R membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B complement(2708325..2709410) Escherichia coli BW2952 7952854 YP_002927635.1 CDS srlA NC_012759.1 2709666 2710229 D MG1655 equivalent: b2702; glucitol/sorbitol-specific enzyme IIC component of PTS 2709666..2710229 Escherichia coli BW2952 7954240 YP_002927636.1 CDS srlE NC_012759.1 2710226 2711185 D MG1655 equivalent: b2703; glucitol/sorbitol-specific enzyme IIB component of PTS 2710226..2711185 Escherichia coli BW2952 7953795 YP_002927637.1 CDS srlB NC_012759.1 2711196 2711567 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA 2711196..2711567 Escherichia coli BW2952 7953794 YP_002927638.1 CDS srlD NC_012759.1 2711571 2712350 D catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 2711571..2712350 Escherichia coli BW2952 7953793 YP_002927639.1 CDS gutM NC_012759.1 2712455 2712814 D regulator for glucitol utilization; DNA-binding transcriptional activator GutM 2712455..2712814 Escherichia coli BW2952 7956058 YP_002927640.1 CDS srlR NC_012759.1 2712881 2713654 D regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 2712881..2713654 Escherichia coli BW2952 7953390 YP_002927641.1 CDS gutQ NC_012759.1 2713647 2714612 D catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 2713647..2714612 Escherichia coli BW2952 7953484 YP_002927642.1 CDS norR NC_012759.1 2714609 2716123 R Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcriptional regulator complement(2714609..2716123) Escherichia coli BW2952 7955319 YP_002927643.1 CDS norV NC_012759.1 2716310 2717749 D detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin 2716310..2717749 Escherichia coli BW2952 7953369 YP_002927644.1 CDS norW NC_012759.1 2717746 2718879 D catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 2717746..2718879 Escherichia coli BW2952 7953612 YP_002927645.1 CDS hypF NC_012759.1 2719007 2721259 R MG1655 equivalent: b2712; carbamoyl phosphate phosphatase and maturation protein for [NiFe] hydrogenases complement(2719007..2721259) Escherichia coli BW2952 7954355 YP_002927646.1 CDS hydN NC_012759.1 2721412 2721939 R involved in electron transport from formate to hydrogen; electron transport protein HydN complement(2721412..2721939) Escherichia coli BW2952 7952591 YP_002927647.1 CDS ascG NC_012759.1 2722088 2723101 R MG1655 equivalent: b2714; DNA-binding transcriptional repressor complement(2722088..2723101) Escherichia coli BW2952 7953617 YP_002927648.1 CDS ascF NC_012759.1 2723358 2724815 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC 2723358..2724815 Escherichia coli BW2952 7953455 YP_002927649.1 CDS ascB NC_012759.1 2724824 2726248 D MG1655 equivalent: b2716; cryptic 6-phospho-beta-glucosidase 2724824..2726248 Escherichia coli BW2952 7953660 YP_002927650.1 CDS hycI NC_012759.1 2726407 2726877 R involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease complement(2726407..2726877) Escherichia coli BW2952 7953165 YP_002927651.1 CDS hycH NC_012759.1 2726870 2727280 R MG1655 equivalent: b2718; protein required for maturation of hydrogenase 3 complement(2726870..2727280) Escherichia coli BW2952 7955777 YP_002927652.1 CDS hycG NC_012759.1 2727277 2728044 R MG1655 equivalent: b2719; hydrogenase 3 and formate hydrogenase complex, HycG subunit complement(2727277..2728044) Escherichia coli BW2952 7955804 YP_002927653.1 CDS hycF NC_012759.1 2728044 2728586 R electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit complement(2728044..2728586) Escherichia coli BW2952 7953943 YP_002927654.1 CDS hycE NC_012759.1 2728596 2730305 R MG1655 equivalent: b2721; hydrogenase 3, large subunit complement(2728596..2730305) Escherichia coli BW2952 7953625 YP_002927655.1 CDS hycD NC_012759.1 2730323 2731246 R MG1655 equivalent: b2722; hydrogenase 3, membrane subunit complement(2730323..2731246) Escherichia coli BW2952 7953945 YP_002927656.1 CDS hycC NC_012759.1 2731249 2733075 R catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 complement(2731249..2733075) Escherichia coli BW2952 7953946 YP_002927657.1 CDS hycB NC_012759.1 2733072 2733683 R MG1655 equivalent: b2724; hydrogenase 3, Fe-S subunit complement(2733072..2733683) Escherichia coli BW2952 7953947 YP_002927658.1 CDS hycA NC_012759.1 2733808 2734269 R regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA complement(2733808..2734269) Escherichia coli BW2952 7953944 YP_002927659.1 CDS hypA NC_012759.1 2734481 2734831 D plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 2734481..2734831 Escherichia coli BW2952 7955925 YP_002927660.1 CDS hypB NC_012759.1 2734835 2735707 D GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 2734835..2735707 Escherichia coli BW2952 7955796 YP_002927661.1 CDS hypC NC_012759.1 2735698 2735970 D HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 2735698..2735970 Escherichia coli BW2952 7953877 YP_002927662.1 CDS hypD NC_012759.1 2735970 2737091 D MG1655 equivalent: b2729; hydrogenase maturation protein 2735970..2737091 Escherichia coli BW2952 7955806 YP_002927663.1 CDS hypE NC_012759.1 2737130 2738098 D MG1655 equivalent: b2730; carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein 2737130..2738098 Escherichia coli BW2952 7955805 YP_002927664.1 CDS fhlA NC_012759.1 2738172 2740250 D MG1655 equivalent: b2731; DNA-binding transcriptional activator 2738172..2740250 Escherichia coli BW2952 7952592 YP_002927665.1 CDS ygbA NC_012759.1 2740287 2740640 R MG1655 equivalent: b2732; hypothetical protein complement(2740287..2740640) Escherichia coli BW2952 7953380 YP_002927666.1 CDS mutS NC_012759.1 2740927 2743488 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 2740927..2743488 Escherichia coli BW2952 7955397 YP_002927667.1 CDS pphB NC_012759.1 2743594 2744250 D MG1655 equivalent: b2734; serine/threonine-specific protein phosphatase 2 2743594..2744250 Escherichia coli BW2952 7954254 YP_002927668.1 CDS ygbI NC_012759.1 2744301 2745098 R MG1655 equivalent: b2735; putative DNA-binding transcriptional regulator complement(2744301..2745098) Escherichia coli BW2952 7956035 YP_002927669.1 CDS ygbJ NC_012759.1 2745264 2746172 D MG1655 equivalent: b2736; putative dehydrogenase, with NAD(P)-binding Rossmann-fold domain 2745264..2746172 Escherichia coli BW2952 7954773 YP_002927670.1 CDS ygbK NC_012759.1 2746169 2747335 D MG1655 equivalent: b2737; hypothetical protein 2746169..2747335 Escherichia coli BW2952 7954717 YP_002927671.1 CDS ygbL NC_012759.1 2747427 2748065 D MG1655 equivalent: b2738; putative aldolase 2747427..2748065 Escherichia coli BW2952 7953004 YP_002927672.1 CDS ygbM NC_012759.1 2748070 2748846 D MG1655 equivalent: b2739; hypothetical protein 2748070..2748846 Escherichia coli BW2952 7954694 YP_002927673.1 CDS ygbN NC_012759.1 2748935 2750299 D member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; inner membrane permease YgbN 2748935..2750299 Escherichia coli BW2952 7953005 YP_002927674.1 CDS rpoS NC_012759.1 2750393 2751385 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS complement(2750393..2751385) Escherichia coli BW2952 7955697 YP_002927675.1 CDS nlpD NC_012759.1 2751448 2752587 R outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD complement(2751448..2752587) Escherichia coli BW2952 7955992 YP_002927676.1 CDS pcm NC_012759.1 2752727 2753353 R catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase complement(2752727..2753353) Escherichia coli BW2952 7955199 YP_002927677.1 CDS surE NC_012759.1 2753347 2754108 R catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE complement(2753347..2754108) Escherichia coli BW2952 7954160 YP_002927678.1 CDS truD NC_012759.1 2754089 2755138 R catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D complement(2754089..2755138) Escherichia coli BW2952 7952584 YP_002927679.1 CDS ispF NC_012759.1 2755135 2755614 R catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(2755135..2755614) Escherichia coli BW2952 7955819 YP_002927680.1 CDS ispD NC_012759.1 2755614 2756324 R 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(2755614..2756324) Escherichia coli BW2952 7952254 YP_002927681.1 CDS ftsB NC_012759.1 2756343 2756654 R forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB complement(2756343..2756654) Escherichia coli BW2952 7952331 YP_002927682.1 CDS ygbE NC_012759.1 2756848 2757171 R MG1655 equivalent: b2749; hypothetical protein complement(2756848..2757171) Escherichia coli BW2952 7952616 YP_002927683.1 CDS cysC NC_012759.1 2757221 2757826 R converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase complement(2757221..2757826) Escherichia coli BW2952 7952680 YP_002927684.1 CDS cysN NC_012759.1 2757826 2759253 R may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 complement(2757826..2759253) Escherichia coli BW2952 7952420 YP_002927685.1 CDS cysD NC_012759.1 2759255 2760163 R with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 complement(2759255..2760163) Escherichia coli BW2952 7956088 YP_002927686.1 CDS iap NC_012759.1 2760415 2761452 D catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase isozyme conversion aminopeptidase 2760415..2761452 Escherichia coli BW2952 7956089 YP_002927687.1 CDS ygbF NC_012759.1 2762403 2762687 R MG1655 equivalent: b2754; hypothetical protein complement(2762403..2762687) Escherichia coli BW2952 7952472 YP_002927688.1 CDS ygbT NC_012759.1 2762689 2763606 R MG1655 equivalent: b2755; hypothetical protein complement(2762689..2763606) Escherichia coli BW2952 7955398 YP_002927689.1 CDS ygcH NC_012759.1 2763622 2764221 R MG1655 equivalent: b2756; hypothetical protein complement(2763622..2764221) Escherichia coli BW2952 7952855 YP_002927690.1 CDS ygcI NC_012759.1 2764208 2764882 R MG1655 equivalent: b2757; hypothetical protein complement(2764208..2764882) Escherichia coli BW2952 7955399 YP_002927691.1 CDS ygcJ NC_012759.1 2764885 2765976 R MG1655 equivalent: b2758; hypothetical protein complement(2764885..2765976) Escherichia coli BW2952 7955400 YP_002927692.1 CDS ygcK NC_012759.1 2765989 2766471 R MG1655 equivalent: b2759; hypothetical protein complement(2765989..2766471) Escherichia coli BW2952 7955401 YP_002927693.1 CDS ygcL NC_012759.1 2766464 2767972 R unknown function; in E. coli this protein is regulated by BaeR, a protein involved in resistance to novobiocin and deoxycholate; hypothetical protein complement(2766464..2767972) Escherichia coli BW2952 7955402 YP_002927694.1 CDS ygcB NC_012759.1 2768387 2771053 R MG1655 equivalent: b2761; hypothetical protein complement(2768387..2771053) Escherichia coli BW2952 7955403 YP_002927695.1 CDS cysH NC_012759.1 2771412 2772146 R catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase complement(2771412..2772146) Escherichia coli BW2952 7953093 YP_002927696.1 CDS cysI NC_012759.1 2772221 2773933 R hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta complement(2772221..2773933) Escherichia coli BW2952 7952324 YP_002927697.1 CDS cysJ NC_012759.1 2773933 2775732 R catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha complement(2773933..2775732) Escherichia coli BW2952 7956095 YP_002927698.1 CDS sscR NC_012759.1 2776048 2776413 D MG1655 equivalent: b2765; 6-pyruvoyl tetrahydrobiopterin synthase 2776048..2776413 Escherichia coli BW2952 7956094 YP_002927699.1 CDS ygcN NC_012759.1 2776491 2777762 D MG1655 equivalent: b2766; putative oxidoreductase with FAD/NAD(P)-binding domain 2776491..2777762 Escherichia coli BW2952 7952381 YP_002927700.1 CDS ygcO NC_012759.1 2777753 2778013 D MG1655 equivalent: b2767; putative 4Fe-4S cluster-containing protein 2777753..2778013 Escherichia coli BW2952 7955243 YP_002927701.1 CDS ygcP NC_012759.1 2778030 2778605 D MG1655 equivalent: b2768; putative anti-terminator regulatory protein 2778030..2778605 Escherichia coli BW2952 7954591 YP_002927702.1 CDS ygcQ NC_012759.1 2778753 2779613 R MG1655 equivalent: b2769; putative flavoprotein complement(2778753..2779613) Escherichia coli BW2952 7954654 YP_002927703.1 CDS ygcR NC_012759.1 2779610 2780389 R MG1655 equivalent: b2770; putative flavoprotein complement(2779610..2780389) Escherichia coli BW2952 7954906 YP_002927704.1 CDS ygcS NC_012759.1 2780367 2781704 R MG1655 equivalent: b2771; putative transporter complement(2780367..2781704) Escherichia coli BW2952 7954907 YP_002927705.1 CDS ygcU NC_012759.1 2781798 2783252 R MG1655 equivalent: b4463; putative FAD containing dehydrogenase complement(2781798..2783252) Escherichia coli BW2952 7955663 YP_002927706.1 CDS ygcW NC_012759.1 2783322 2784107 R MG1655 equivalent: b2774; putative deoxygluconate dehydrogenase complement(2783322..2784107) Escherichia coli BW2952 7954866 YP_002927707.1 CDS yqcE NC_012759.1 2784426 2785703 D MG1655 equivalent: b2775; putative transporter 2784426..2785703 Escherichia coli BW2952 7954718 YP_002927708.1 CDS ygcE NC_012759.1 2785730 2787208 D MG1655 equivalent: b2776; putative kinase 2785730..2787208 Escherichia coli BW2952 7955698 YP_002927709.1 CDS ygcF NC_012759.1 2788581 2789252 R MG1655 equivalent: b2777; hypothetical protein complement(2788581..2789252) Escherichia coli BW2952 7955096 YP_002927710.1 CDS ygcG NC_012759.1 2789545 2790417 D MG1655 equivalent: b2778; hypothetical protein 2789545..2790417 Escherichia coli BW2952 7952856 YP_002927711.1 CDS eno NC_012759.1 2790477 2791775 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(2790477..2791775) Escherichia coli BW2952 7955504 YP_002927712.1 CDS pyrG NC_012759.1 2791863 2793500 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(2791863..2793500) Escherichia coli BW2952 7953522 YP_002927713.1 CDS mazG NC_012759.1 2793728 2794519 R functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase complement(2793728..2794519) Escherichia coli BW2952 7953173 YP_002927714.1 CDS chpA NC_012759.1 2794590 2794925 R MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system; toxin ChpA complement(2794590..2794925) Escherichia coli BW2952 7954412 YP_002927715.1 CDS chpR NC_012759.1 2794925 2795173 R part of the MazF-MazE toxin-antitoxin system; conteracts MazF; antitoxin MazE complement(2794925..2795173) Escherichia coli BW2952 7956160 YP_002927716.1 CDS relA NC_012759.1 2795251 2797257 R MG1655 equivalent: b2714; GTP diphosphokinase complement(2795251..2797257) Escherichia coli BW2952 7952486 YP_002927717.1 CDS BWG_2520 NC_012759.1 2797242 2798147 R IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD complement(2797242..2798147) Escherichia coli BW2952 7953876 YP_002927718.1 CDS BWG_2521 NC_012759.1 2798105 2798470 R IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein complement(2798105..2798470) Escherichia coli BW2952 7956183 YP_002927719.1 CDS rumA NC_012759.1 2798869 2800170 R in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase complement(2798869..2800170) Escherichia coli BW2952 7952206 YP_002927720.1 CDS barA NC_012759.1 2800227 2802983 D part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 2800227..2802983 Escherichia coli BW2952 7952242 YP_002927721.1 CDS gudD NC_012759.1 2803215 2804555 R MG1655 equivalent: b2787; (D)-glucarate dehydratase 1 complement(2803215..2804555) Escherichia coli BW2952 7953931 YP_002927722.1 CDS gudX NC_012759.1 2804576 2805916 R MG1655 equivalent: b2788; putative glucarate dehydratase complement(2804576..2805916) Escherichia coli BW2952 7952217 YP_002927723.1 CDS gudP NC_012759.1 2805918 2807270 R MG1655 equivalent: b2789; putative D-glucarate transporter complement(2805918..2807270) Escherichia coli BW2952 7954917 YP_002927724.1 CDS yqcA NC_012759.1 2807705 2808154 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(2807705..2808154) Escherichia coli BW2952 7954720 YP_002927725.1 CDS truC NC_012759.1 2808172 2808954 R catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C complement(2808172..2808954) Escherichia coli BW2952 7954908 YP_002927726.1 CDS yqcC NC_012759.1 2808954 2809283 R MG1655 equivalent: b2792; hypothetical protein complement(2808954..2809283) Escherichia coli BW2952 7956201 YP_002927727.1 CDS syd NC_012759.1 2809905 2810450 R putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd complement(2809905..2810450) Escherichia coli BW2952 7952090 YP_002927728.1 CDS queF NC_012759.1 2810518 2811366 D catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 2810518..2811366 Escherichia coli BW2952 7955404 YP_002927729.1 CDS ygdH NC_012759.1 2811478 2812842 D MG1655 equivalent: b2795; hypothetical protein 2811478..2812842 Escherichia coli BW2952 7952385 YP_002927730.1 CDS sdaC NC_012759.1 2813399 2814688 D MG1655 equivalent: b2796; putative serine transporter 2813399..2814688 Escherichia coli BW2952 7953006 YP_002927731.1 CDS sdaB NC_012759.1 2814746 2816113 D MG1655 equivalent: b2797; L-serine deaminase II 2814746..2816113 Escherichia coli BW2952 7955590 YP_002927732.1 CDS xni NC_012759.1 2816135 2816980 D has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 2816135..2816980 Escherichia coli BW2952 7954171 YP_002927733.1 CDS fucO NC_012759.1 2817035 2818186 R MG1655 equivalent: b2799; L-1,2-propanediol oxidoreductase complement(2817035..2818186) Escherichia coli BW2952 7956064 YP_002927734.1 CDS fucA NC_012759.1 2818211 2818858 R catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase complement(2818211..2818858) Escherichia coli BW2952 7954106 YP_002927735.1 CDS fucP NC_012759.1 2819405 2820721 D MG1655 equivalent: b2801; L-fucose transporter 2819405..2820721 Escherichia coli BW2952 7954140 YP_002927736.1 CDS fucI NC_012759.1 2820754 2822529 D catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 2820754..2822529 Escherichia coli BW2952 7954138 YP_002927737.1 CDS fucK NC_012759.1 2822608 2824056 D MG1655 equivalent: b2803; L-fuculokinase 2822608..2824056 Escherichia coli BW2952 7954136 YP_002927738.1 CDS fucU NC_012759.1 2824058 2824480 D MG1655 equivalent: b2804; L-fucose mutarotase 2824058..2824480 Escherichia coli BW2952 7954139 YP_002927739.1 CDS fucR NC_012759.1 2824538 2825269 D regulates expression of genes involved in L-fucose utilization; DNA-binding transcriptional activator FucR 2824538..2825269 Escherichia coli BW2952 7954137 YP_002927740.1 CDS ygdE NC_012759.1 2825313 2826413 R MG1655 equivalent: b2806; putative RNA 2'-O-ribose methyltransferase complement(2825313..2826413) Escherichia coli BW2952 7953381 YP_002927741.1 CDS ygdD NC_012759.1 2826406 2826801 R MG1655 equivalent: b2807; hypothetical protein complement(2826406..2826801) Escherichia coli BW2952 7955155 YP_002927742.1 CDS gcvA NC_012759.1 2826820 2827737 R Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA complement(2826820..2827737) Escherichia coli BW2952 7952681 YP_002927743.1 CDS ygdI NC_012759.1 2828088 2828315 R MG1655 equivalent: b2809; hypothetical protein complement(2828088..2828315) Escherichia coli BW2952 7952190 YP_002927744.1 CDS csdA NC_012759.1 2828507 2829712 D MG1655 equivalent: b2810; cysteine sulfinate desulfinase 2828507..2829712 Escherichia coli BW2952 7955405 YP_002927745.1 CDS csdE NC_012759.1 2829712 2830155 D MG1655 equivalent: b2811; putative Fe-S metabolism protein 2829712..2830155 Escherichia coli BW2952 7953183 YP_002927746.1 CDS ygdL NC_012759.1 2830206 2831012 R MG1655 equivalent: b2812; hypothetical protein complement(2830206..2831012) Escherichia coli BW2952 7954872 YP_002927747.1 CDS mltA NC_012759.1 2831251 2832348 R membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A complement(2831251..2832348) Escherichia coli BW2952 7952858 YP_002927748.1 CDS amiC NC_012759.1 2832927 2834180 R MG1655 equivalent: b2817; N-acetylmuramoyl-L-alanine amidase complement(2832927..2834180) Escherichia coli BW2952 7952144 YP_002927749.1 CDS argA NC_012759.1 2834412 2835743 D catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 2834412..2835743 Escherichia coli BW2952 7954343 YP_002927750.1 CDS recD NC_012759.1 2835805 2837631 R helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha complement(2835805..2837631) Escherichia coli BW2952 7953654 YP_002927751.1 CDS recB NC_012759.1 2837631 2841173 R helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta complement(2837631..2841173) Escherichia coli BW2952 7953541 YP_002927752.1 CDS ptrA NC_012759.1 2841166 2844054 R MG1655 equivalent: b2821; protease III complement(2841166..2844054) Escherichia coli BW2952 7953542 YP_002927753.1 CDS recC NC_012759.1 2844230 2847598 R catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma complement(2844230..2847598) Escherichia coli BW2952 7955776 YP_002927754.1 CDS ppdC NC_012759.1 2847611 2847934 R MG1655 equivalent: b2823; hypothetical protein complement(2847611..2847934) Escherichia coli BW2952 7953543 YP_002927755.1 CDS ygdB NC_012759.1 2847919 2848326 R MG1655 equivalent: b2824; hypothetical protein complement(2847919..2848326) Escherichia coli BW2952 7955406 YP_002927756.1 CDS ppdB NC_012759.1 2848323 2848886 R MG1655 equivalent: b2825; hypothetical protein complement(2848323..2848886) Escherichia coli BW2952 7955407 YP_002927757.1 CDS ppdA NC_012759.1 2848877 2849347 R MG1655 equivalent: b2826; hypothetical protein complement(2848877..2849347) Escherichia coli BW2952 7952859 YP_002927758.1 CDS thyA NC_012759.1 2849531 2850325 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(2849531..2850325) Escherichia coli BW2952 7952860 YP_002927759.1 CDS lgt NC_012759.1 2850332 2851207 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(2850332..2851207) Escherichia coli BW2952 7956151 YP_002927760.1 CDS ptsP NC_012759.1 2851358 2853604 R member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain complement(2851358..2853604) Escherichia coli BW2952 7954521 YP_002927761.1 CDS rppH NC_012759.1 2853617 2854147 R hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase complement(2853617..2854147) Escherichia coli BW2952 7953737 YP_002927762.1 CDS ygdT NC_012759.1 2854500 2854646 R MG1655 equivalent: b4610; hypothetical protein complement(2854500..2854646) Escherichia coli BW2952 7954415 YP_002927763.1 CDS mutH NC_012759.1 2854832 2855521 D MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 2854832..2855521 Escherichia coli BW2952 7953970 YP_002927764.1 CDS ygdQ NC_012759.1 2855590 2856303 D MG1655 equivalent: b2832; putative inner membrane protein 2855590..2856303 Escherichia coli BW2952 7954255 YP_002927765.1 CDS ygdR NC_012759.1 2856441 2856659 D MG1655 equivalent: b2833; hypothetical protein 2856441..2856659 Escherichia coli BW2952 7955060 YP_002927766.1 CDS tas NC_012759.1 2856767 2857807 D complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; putative aldo-keto reductase 2856767..2857807 Escherichia coli BW2952 7955505 YP_002927767.1 CDS lplT NC_012759.1 2857839 2859032 R MG1655 equivalent: b2835; lysophospholipid transporter LplT complement(2857839..2859032) Escherichia coli BW2952 7955257 YP_002927768.1 CDS aas NC_012759.1 2859025 2861184 R Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase complement(2859025..2861184) Escherichia coli BW2952 7955007 YP_002927769.1 CDS galR NC_012759.1 2861769 2862800 D controls transcription of galETKM; DNA-binding transcriptional regulator GalR 2861769..2862800 Escherichia coli BW2952 7952092 YP_002927770.1 CDS lysA NC_012759.1 2862807 2864069 R catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase complement(2862807..2864069) Escherichia coli BW2952 7953465 YP_002927771.1 CDS lysR NC_012759.1 2864191 2865126 D activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; LysR family transcriptional regulator 2864191..2865126 Escherichia coli BW2952 7953247 YP_002927772.1 CDS ygeA NC_012759.1 2865113 2865805 R MG1655 equivalent: b2840; putative racemase complement(2865113..2865805) Escherichia coli BW2952 7953422 YP_002927773.1 CDS araE NC_012759.1 2865934 2867352 R MG1655 equivalent: b2841; arabinose transporter complement(2865934..2867352) Escherichia coli BW2952 7955555 YP_002927774.1 CDS kduD NC_012759.1 2867667 2868428 R catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase complement(2867667..2868428) Escherichia coli BW2952 7952492 YP_002927775.1 CDS kduI NC_012759.1 2868458 2869294 R 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase complement(2868458..2869294) Escherichia coli BW2952 7952257 YP_002927776.1 CDS yqeF NC_012759.1 2869581 2870762 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase complement(2869581..2870762) Escherichia coli BW2952 7954597 YP_002927777.1 CDS yqeG NC_012759.1 2871017 2872246 D MG1655 equivalent: b2845; putative transporter 2871017..2872246 Escherichia coli BW2952 7954613 YP_002927778.1 CDS yqeH NC_012759.1 2872706 2873338 D MG1655 equivalent: b2846; hypothetical protein 2872706..2873338 Escherichia coli BW2952 7955699 YP_002927779.1 CDS yqeI NC_012759.1 2873672 2874481 D MG1655 equivalent: b2847; putative transcriptional regulator 2873672..2874481 Escherichia coli BW2952 7953077 YP_002927780.1 CDS yqeJ NC_012759.1 2874474 2874956 D MG1655 equivalent: b2848; hypothetical protein 2874474..2874956 Escherichia coli BW2952 7955635 YP_002927781.1 CDS yqeK NC_012759.1 2875105 2875530 R MG1655 equivalent: b2849; hypothetical protein complement(2875105..2875530) Escherichia coli BW2952 7955506 YP_002927782.1 CDS ygeG NC_012759.1 2876438 2876929 D MG1655 equivalent: b2851; putative chaperone 2876438..2876929 Escherichia coli BW2952 7955408 YP_002927783.1 CDS ygeH NC_012759.1 2877264 2878640 D MG1655 equivalent: b2852; transcriptional regulator 2877264..2878640 Escherichia coli BW2952 7954690 YP_002927784.1 CDS ygeI NC_012759.1 2878808 2879026 D MG1655 equivalent: b2853; hypothetical protein 2878808..2879026 Escherichia coli BW2952 7955757 YP_002927785.1 CDS insD NC_012759.1 2881542 2882447 R IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD complement(2881542..2882447) Escherichia coli BW2952 7955507 YP_002927786.1 CDS insC NC_012759.1 2882405 2882770 R IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein complement(2882405..2882770) Escherichia coli BW2952 7954079 YP_002927787.1 CDS ygeR NC_012759.1 2884306 2885061 R MG1655 equivalent: b2865; hypothetical protein complement(2884306..2885061) Escherichia coli BW2952 7952067 YP_002927788.1 CDS xdhA NC_012759.1 2885515 2887773 D putative molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 2885515..2887773 Escherichia coli BW2952 7956121 YP_002927789.1 CDS xdhB NC_012759.1 2887784 2888662 D FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 2887784..2888662 Escherichia coli BW2952 7956278 YP_002927790.1 CDS xdhC NC_012759.1 2888659 2889138 D iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; xanthine dehydrogenase subunit XdhC 2888659..2889138 Escherichia coli BW2952 7956276 YP_002927791.1 CDS ygeV NC_012759.1 2889178 2890956 R MG1655 equivalent: b2869; putative DNA-binding transcriptional regulator complement(2889178..2890956) Escherichia coli BW2952 7956277 YP_002927792.1 CDS ygeW NC_012759.1 2891432 2892622 D MG1655 equivalent: b2870; aspartate/ornithine carbamoyltransferase family protein 2891432..2892622 Escherichia coli BW2952 7954774 YP_002927793.1 CDS ygeX NC_012759.1 2892680 2893876 D catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 2892680..2893876 Escherichia coli BW2952 7953007 YP_002927794.1 CDS ygeY NC_012759.1 2893934 2895145 D Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 2893934..2895145 Escherichia coli BW2952 7952232 YP_002927795.1 CDS hyuA NC_012759.1 2895198 2896583 D catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 2895198..2896583 Escherichia coli BW2952 7955285 YP_002927796.1 CDS yqeA NC_012759.1 2896631 2897563 D catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 2896631..2897563 Escherichia coli BW2952 7953498 YP_002927797.1 CDS yqeB NC_012759.1 2897784 2899409 R MG1655 equivalent: b2875; hypothetical protein complement(2897784..2899409) Escherichia coli BW2952 7954639 YP_002927798.1 CDS yqeC NC_012759.1 2899457 2900227 R MG1655 equivalent: b2876; hypothetical protein complement(2899457..2900227) Escherichia coli BW2952 7953079 YP_002927799.1 CDS ygfJ NC_012759.1 2900330 2900908 D MG1655 equivalent: b2877; hypothetical protein 2900330..2900908 Escherichia coli BW2952 7952861 YP_002927800.1 CDS ygfK NC_012759.1 2901230 2904328 D with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; putative selenate reductase subunit YgfK 2901230..2904328 Escherichia coli BW2952 7953008 YP_002927801.1 CDS ssnA NC_012759.1 2904331 2905659 D in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; putative chlorohydrolase/aminohydrolase 2904331..2905659 Escherichia coli BW2952 7955252 YP_002927802.1 CDS ygfM NC_012759.1 2905710 2906489 D with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; putative selenate reductase subunit YgfM 2905710..2906489 Escherichia coli BW2952 7954693 YP_002927803.1 CDS xdhD NC_012759.1 2906486 2909356 D with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; putative selenate reductase subunit YgfN 2906486..2909356 Escherichia coli BW2952 7955237 YP_002927804.1 CDS ygfO NC_012759.1 2909521 2910921 D MG1655 equivalent: b2882; putative transporter 2909521..2910921 Escherichia coli BW2952 7953735 YP_002927805.1 CDS guaD NC_012759.1 2910936 2912255 D Catalyzes the deamination of guanine; guanine deaminase 2910936..2912255 Escherichia coli BW2952 7955700 YP_002927806.1 CDS ygfQ NC_012759.1 2912291 2913658 D MG1655 equivalent: b4464; putative transporter 2912291..2913658 Escherichia coli BW2952 7953884 YP_002927807.1 CDS ygfS NC_012759.1 2913694 2914182 R MG1655 equivalent: b2886; putative oxidoreductase, 4Fe-4S ferredoxin-type subunit complement(2913694..2914182) Escherichia coli BW2952 7955716 YP_002927808.1 CDS ygfT NC_012759.1 2914182 2916101 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); putative oxidoreductase Fe-S binding subunit complement(2914182..2916101) Escherichia coli BW2952 7955251 YP_002927809.1 CDS ygfU NC_012759.1 2916537 2917985 D MG1655 equivalent: b2888; putative transporter 2916537..2917985 Escherichia coli BW2952 7953721 YP_002927810.1 CDS idi NC_012759.1 2918235 2918783 D catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 2918235..2918783 Escherichia coli BW2952 7955701 YP_002927811.1 CDS lysS NC_012759.1 2918827 2920344 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(2918827..2920344) Escherichia coli BW2952 7954054 YP_002927812.1 CDS prfB NC_012759.1 2920354 2921452 R recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 complement(join(2920354..2921377,2921379..2921452)) Escherichia coli BW2952 7954183 YP_002927813.1 CDS recJ NC_012759.1 2921543 2923276 R 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ complement(2921543..2923276) Escherichia coli BW2952 7954475 YP_002927814.1 CDS dsbC NC_012759.1 2923282 2923992 R DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC complement(2923282..2923992) Escherichia coli BW2952 7956065 YP_002927815.1 CDS xerD NC_012759.1 2924017 2924913 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD complement(2924017..2924913) Escherichia coli BW2952 7955791 YP_002927816.1 CDS fldB NC_012759.1 2925025 2925546 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 2925025..2925546 Escherichia coli BW2952 7956047 YP_002927817.1 CDS ygfX NC_012759.1 2925586 2925993 R MG1655 equivalent: b2896; hypothetical protein complement(2925586..2925993) Escherichia coli BW2952 7953610 YP_002927818.1 CDS ygfY NC_012759.1 2925974 2926240 R MG1655 equivalent: b2897; hypothetical protein complement(2925974..2926240) Escherichia coli BW2952 7955409 YP_002927819.1 CDS ygfZ NC_012759.1 2926483 2927463 D physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; putative global regulator 2926483..2927463 Escherichia coli BW2952 7952862 YP_002927820.1 CDS yqfA NC_012759.1 2927659 2928318 R MG1655 equivalent: b2899; putative oxidoreductase, inner membrane subunit complement(2927659..2928318) Escherichia coli BW2952 7954909 YP_002927821.1 CDS yqfB NC_012759.1 2928482 2928793 R MG1655 equivalent: b2900; hypothetical protein complement(2928482..2928793) Escherichia coli BW2952 7955254 YP_002927822.1 CDS bglA NC_012759.1 2928832 2930271 D MG1655 equivalent: b2901; 6-phospho-beta-glucosidase 2928832..2930271 Escherichia coli BW2952 7952863 YP_002927823.1 CDS ygfF NC_012759.1 2930328 2931071 R MG1655 equivalent: b2902; hypothetical protein complement(2930328..2931071) Escherichia coli BW2952 7952376 YP_002927824.1 CDS gcvP NC_012759.1 2931338 2934211 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase complement(2931338..2934211) Escherichia coli BW2952 7955180 YP_002927825.1 CDS gcvH NC_012759.1 2934330 2934719 R part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H complement(2934330..2934719) Escherichia coli BW2952 7953860 YP_002927826.1 CDS gcvT NC_012759.1 2934743 2935837 R catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T complement(2934743..2935837) Escherichia coli BW2952 7953859 YP_002927827.1 CDS visC NC_012759.1 2936285 2937487 R MG1655 equivalent: b2906; hypothetical protein complement(2936285..2937487) Escherichia coli BW2952 7952469 YP_002927828.1 CDS ubiH NC_012759.1 2937510 2938688 R Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase complement(2937510..2938688) Escherichia coli BW2952 7955239 YP_002927829.1 CDS pepP NC_012759.1 2938685 2940010 R exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II complement(2938685..2940010) Escherichia coli BW2952 7952265 YP_002927830.1 CDS ygfB NC_012759.1 2940036 2940614 R the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein complement(2940036..2940614) Escherichia coli BW2952 7955767 YP_002927831.1 CDS zapA NC_012759.1 2940782 2941111 D MG1655 equivalent: b2910; Z-ring-associated protein 2940782..2941111 Escherichia coli BW2952 7955410 YP_002927832.1 CDS ygfA NC_012759.1 2941411 2941959 D ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; putative ligase 2941411..2941959 Escherichia coli BW2952 7952191 YP_002927833.1 CDS serA NC_012759.1 2942348 2943580 R catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase complement(2942348..2943580) Escherichia coli BW2952 7952192 YP_002927834.1 CDS rpiA NC_012759.1 2943836 2944495 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(2943836..2944495) Escherichia coli BW2952 7953207 YP_002927835.1 CDS argP NC_012759.1 2944923 2945816 D specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 2944923..2945816 Escherichia coli BW2952 7955973 YP_002927836.1 CDS scpA NC_012759.1 2946020 2948164 D MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 2946020..2948164 Escherichia coli BW2952 7953400 YP_002927837.1 CDS argK NC_012759.1 2948157 2949152 D functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase 2948157..2949152 Escherichia coli BW2952 7954261 YP_002927838.1 CDS scpB NC_012759.1 2949163 2949948 D catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA; methylmalonyl-CoA decarboxylase 2949163..2949948 Escherichia coli BW2952 7954225 YP_002927839.1 CDS scpC NC_012759.1 2949972 2951450 D MG1655 equivalent: b2920; propionyl-CoA:succinate-CoA transferase 2949972..2951450 Escherichia coli BW2952 7954260 YP_002927840.1 CDS ygfI NC_012759.1 2951447 2952343 R MG1655 equivalent: b2921; putative DNA-binding transcriptional regulator complement(2951447..2952343) Escherichia coli BW2952 7955774 YP_002927841.1 CDS yggE NC_012759.1 2952510 2953250 R MG1655 equivalent: b2922; hypothetical protein complement(2952510..2953250) Escherichia coli BW2952 7954775 YP_002927842.1 CDS argO NC_012759.1 2953343 2953978 R Involved in the export of arginine; arginine exporter protein complement(2953343..2953978) Escherichia coli BW2952 7952864 YP_002927843.1 CDS mscS NC_012759.1 2954117 2954977 R participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS complement(2954117..2954977) Escherichia coli BW2952 7952494 YP_002927844.1 CDS fbaA NC_012759.1 2955335 2956414 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase complement(2955335..2956414) Escherichia coli BW2952 7954218 YP_002927845.1 CDS pgk NC_012759.1 2956629 2957792 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(2956629..2957792) Escherichia coli BW2952 7953638 YP_002927846.1 CDS epd NC_012759.1 2957842 2958861 R NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase complement(2957842..2958861) Escherichia coli BW2952 7954533 YP_002927847.1 CDS frcK NC_012759.1 2959146 2959859 R MG1655 equivalent: b2928; putative fructose transport system kinase complement(2959146..2959859) Escherichia coli BW2952 7953240 YP_002927848.1 CDS yggD NC_012759.1 2959856 2960365 R MG1655 equivalent: b2929; putative DNA-binding transcriptional regulator complement(2959856..2960365) Escherichia coli BW2952 7953086 YP_002927849.1 CDS yggF NC_012759.1 2960387 2961352 R MG1655 equivalent: b2930; fructose-1,6-bisphosphatase II-like protein complement(2960387..2961352) Escherichia coli BW2952 7954776 YP_002927850.1 CDS yggP NC_012759.1 2961349 2962626 R MG1655 equivalent: b4465; putative dehydrogenase complement(2961349..2962626) Escherichia coli BW2952 7954944 YP_002927851.1 CDS cmtA NC_012759.1 2962641 2964029 R MG1655 equivalent: b2933; putative fused mannitol-specific PTS enzymes: IIB component/IIC component complement(2962641..2964029) Escherichia coli BW2952 7954713 YP_002927852.1 CDS cmtB NC_012759.1 2964057 2964500 R TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; putative mannitol phosphotransferase subunit EIIA complement(2964057..2964500) Escherichia coli BW2952 7954914 YP_002927853.1 CDS tktA NC_012759.1 2964814 2966805 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(2964814..2966805) Escherichia coli BW2952 7955132 YP_002927854.1 CDS yggG NC_012759.1 2967083 2967841 D MG1655 equivalent: b2936; putative peptidase 2967083..2967841 Escherichia coli BW2952 7956174 YP_002927855.1 CDS speB NC_012759.1 2968047 2968967 R catalyzes the formation of putrescine from agmatine; agmatinase complement(2968047..2968967) Escherichia coli BW2952 7955286 YP_002927856.1 CDS speA NC_012759.1 2969105 2971081 R catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase complement(2969105..2971081) Escherichia coli BW2952 7952434 YP_002927857.1 CDS yqgB NC_012759.1 2971090 2971221 R MG1655 equivalent: b2939; hypothetical protein complement(2971090..2971221) Escherichia coli BW2952 7952579 YP_002927858.1 CDS yqgC NC_012759.1 2971357 2971572 D MG1655 equivalent: b2940; hypothetical protein 2971357..2971572 Escherichia coli BW2952 7955411 YP_002927859.1 CDS yqgD NC_012759.1 2971569 2971820 R MG1655 equivalent: b2941; putative inner membrane protein complement(2971569..2971820) Escherichia coli BW2952 7955508 YP_002927860.1 CDS metK NC_012759.1 2971876 2973030 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 2971876..2973030 Escherichia coli BW2952 7955008 YP_002927861.1 CDS galP NC_012759.1 2973454 2974848 D MG1655 equivalent: b2943; D-galactose transporter 2973454..2974848 Escherichia coli BW2952 7954242 YP_002927862.1 CDS yggI NC_012759.1 2974925 2975422 D MG1655 equivalent: b2944; hypothetical protein 2974925..2975422 Escherichia coli BW2952 7953243 YP_002927863.1 CDS endA NC_012759.1 2975517 2976224 D MG1655 equivalent: b2945; DNA-specific endonuclease I 2975517..2976224 Escherichia coli BW2952 7953009 YP_002927864.1 CDS rsmE NC_012759.1 2976304 2977035 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 2976304..2977035 Escherichia coli BW2952 7953492 YP_002927865.1 CDS gshB NC_012759.1 2977048 2977998 D catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 2977048..2977998 Escherichia coli BW2952 7955509 YP_002927866.1 CDS yqgE NC_012759.1 2978107 2978670 D MG1655 equivalent: b2948; hypothetical protein 2978107..2978670 Escherichia coli BW2952 7953840 YP_002927867.1 CDS yqgF NC_012759.1 2978670 2979086 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 2978670..2979086 Escherichia coli BW2952 7955510 YP_002927868.1 CDS yggR NC_012759.1 2979270 2980250 R MG1655 equivalent: b2950; putative transporter complement(2979270..2980250) Escherichia coli BW2952 7954946 YP_002927869.1 CDS yggS NC_012759.1 2980268 2980972 D MG1655 equivalent: b2951; putative enzyme 2980268..2980972 Escherichia coli BW2952 7955664 YP_002927870.1 CDS yggT NC_012759.1 2980990 2981556 D MG1655 equivalent: b2952; putative inner membrane protein 2980990..2981556 Escherichia coli BW2952 7954847 YP_002927871.1 CDS yggU NC_012759.1 2981553 2981843 D MG1655 equivalent: b2953; hypothetical protein 2981553..2981843 Escherichia coli BW2952 7955061 YP_002927872.1 CDS rdgB NC_012759.1 2981851 2982444 D HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 2981851..2982444 Escherichia coli BW2952 7953010 YP_002927873.1 CDS yggW NC_012759.1 2982437 2983573 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 2982437..2983573 Escherichia coli BW2952 7953270 YP_002927874.1 CDS yggM NC_012759.1 2983728 2984735 R MG1655 equivalent: b2956; hypothetical protein complement(2983728..2984735) Escherichia coli BW2952 7955238 YP_002927875.1 CDS ansB NC_012759.1 2984852 2985898 R catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II complement(2984852..2985898) Escherichia coli BW2952 7952865 YP_002927876.1 CDS yggN NC_012759.1 2986074 2986793 R MG1655 equivalent: b2958; hypothetical protein complement(2986074..2986793) Escherichia coli BW2952 7954493 YP_002927877.1 CDS yggL NC_012759.1 2986977 2987303 R MG1655 equivalent: b2959; hypothetical protein complement(2986977..2987303) Escherichia coli BW2952 7955412 YP_002927878.1 CDS trmB NC_012759.1 2987303 2988022 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(2987303..2988022) Escherichia coli BW2952 7955413 YP_002927879.1 CDS mutY NC_012759.1 2988183 2989235 D MG1655 equivalent: b2961; adenine DNA glycosylase 2988183..2989235 Escherichia coli BW2952 7956198 YP_002927880.1 CDS yggX NC_012759.1 2989263 2989538 D MG1655 equivalent: b2962; hypothetical protein 2989263..2989538 Escherichia coli BW2952 7952418 YP_002927881.1 CDS mltC NC_012759.1 2989603 2990682 D Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 2989603..2990682 Escherichia coli BW2952 7955810 YP_002927882.1 CDS nupG NC_012759.1 2990884 2992140 D MG1655 equivalent: b2964; nucleoside transporter 2990884..2992140 Escherichia coli BW2952 7954241 YP_002927883.1 CDS speC NC_012759.1 2992190 2994325 R MG1655 equivalent: b2965; ornithine decarboxylase complement(2992190..2994325) Escherichia coli BW2952 7954411 YP_002927884.1 CDS yqgA NC_012759.1 2994723 2995430 D MG1655 equivalent: b2966; putative inner membrane protein 2994723..2995430 Escherichia coli BW2952 7954430 YP_002927885.1 CDS yghD NC_012759.1 2995760 2996296 R MG1655 equivalent: b2968; putative general secretion pathway protein YghD complement(2995760..2996296) Escherichia coli BW2952 7952145 YP_002927886.1 CDS yghG NC_012759.1 2998237 2998647 R MG1655 equivalent: b2971; hypothetical protein complement(2998237..2998647) Escherichia coli BW2952 7955584 YP_002927887.1 CDS pppA NC_012759.1 2998713 2999522 R MG1655 equivalent: b2972; bifunctional prepilin leader peptidase/ methylase complement(2998713..2999522) Escherichia coli BW2952 7955414 YP_002927888.1 CDS yghJ NC_012759.1 2999720 3004282 R MG1655 equivalent: b4466; putative inner membrane lipoprotein complement(2999720..3004282) Escherichia coli BW2952 7952571 YP_002927889.1 CDS glcA NC_012759.1 3004767 3006449 R MG1655 equivalent: b2975; glycolate transporter complement(3004767..3006449) Escherichia coli BW2952 7954981 YP_002927890.1 CDS glcB NC_012759.1 3006804 3008975 R catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G complement(3006804..3008975) Escherichia coli BW2952 7953869 YP_002927891.1 CDS glcG NC_012759.1 3008997 3009401 R MG1655 equivalent: b2977; hypothetical protein complement(3008997..3009401) Escherichia coli BW2952 7954201 YP_002927892.1 CDS glcF NC_012759.1 3009406 3010629 R MG1655 equivalent: b4467; glycolate oxidase iron-sulfur subunit complement(3009406..3010629) Escherichia coli BW2952 7952866 YP_002927893.1 CDS glcE NC_012759.1 3010640 3011692 R MG1655 equivalent: b4468; glycolate oxidase FAD binding subunit complement(3010640..3011692) Escherichia coli BW2952 7953867 YP_002927894.1 CDS glcD NC_012759.1 3011692 3013191 R MG1655 equivalent: b2979; glycolate oxidase subunit GlcD complement(3011692..3013191) Escherichia coli BW2952 7953866 YP_002927895.1 CDS glcC NC_012759.1 3013442 3014206 D MG1655 equivalent: b2980; DNA-binding transcriptional regulator GlcC 3013442..3014206 Escherichia coli BW2952 7953868 YP_002927896.1 CDS insH NC_012759.1 3015348 3016364 D MG1655 equivalent: b2982; IS5 transposase and trans-activator 3015348..3016364 Escherichia coli BW2952 7953432 YP_002927897.1 CDS yghQ NC_012759.1 3016511 3017578 R MG1655 equivalent: b2983; putative inner membrane protein complement(3016511..3017578) Escherichia coli BW2952 7954046 YP_002927898.1 CDS yghR NC_012759.1 3017624 3018382 R MG1655 equivalent: b2984; hypothetical protein complement(3017624..3018382) Escherichia coli BW2952 7955009 YP_002927899.1 CDS yghS NC_012759.1 3018414 3019127 R MG1655 equivalent: b2985; hypothetical protein complement(3018414..3019127) Escherichia coli BW2952 7955543 YP_002927900.1 CDS yghT NC_012759.1 3019301 3019993 D MG1655 equivalent: b2986; hypothetical protein 3019301..3019993 Escherichia coli BW2952 7955544 YP_002927901.1 CDS pitB NC_012759.1 3020042 3021541 R MG1655 equivalent: b2987; phosphate transporter complement(3020042..3021541) Escherichia coli BW2952 7955545 YP_002927902.1 CDS gsp NC_012759.1 3021833 3023692 R catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase complement(3021833..3023692) Escherichia coli BW2952 7954514 YP_002927903.1 CDS yghU NC_012759.1 3023897 3024763 D YghU; B2989; one of eight putative glutathione transferase proteins from E. coli; putative glutathione S-transferase YghU 3023897..3024763 Escherichia coli BW2952 7953684 YP_002927904.1 CDS hybG NC_012759.1 3024886 3025134 R MG1655 equivalent: b2990; hydrogenase 2 accessory protein HypG complement(3024886..3025134) Escherichia coli BW2952 7955598 YP_002927905.1 CDS hybF NC_012759.1 3025147 3025488 R plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF complement(3025147..3025488) Escherichia coli BW2952 7953939 YP_002927906.1 CDS hybE NC_012759.1 3025481 3025969 R MG1655 equivalent: b2992; hydrogenase 2-specific chaperone complement(3025481..3025969) Escherichia coli BW2952 7955799 YP_002927907.1 CDS hybD NC_012759.1 3025962 3026456 R protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase complement(3025962..3026456) Escherichia coli BW2952 7953942 YP_002927908.1 CDS hybC NC_012759.1 3026456 3028159 R involved in hydrogen uptake; hydrogenase 2 large subunit complement(3026456..3028159) Escherichia coli BW2952 7955134 YP_002927909.1 CDS hybB NC_012759.1 3028156 3029334 R HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; putative hydrogenase 2 b cytochrome subunit complement(3028156..3029334) Escherichia coli BW2952 7953940 YP_002927910.1 CDS hybA NC_012759.1 3029324 3030310 R Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA complement(3029324..3030310) Escherichia coli BW2952 7954948 YP_002927911.1 CDS hybO NC_012759.1 3030313 3031431 R involved in hydrogen uptake; hydrogenase 2 small subunit complement(3030313..3031431) Escherichia coli BW2952 7953938 YP_002927912.1 CDS yghW NC_012759.1 3031620 3031907 R MG1655 equivalent: b2998; hypothetical protein complement(3031620..3031907) Escherichia coli BW2952 7953941 YP_002927913.1 CDS yghZ NC_012759.1 3033067 3034107 D MG1655 equivalent: b3001; aldo-keto reductase 3033067..3034107 Escherichia coli BW2952 7955415 YP_002927914.1 CDS yqhA NC_012759.1 3034147 3034641 R MG1655 equivalent: b3002; hypothetical protein complement(3034147..3034641) Escherichia coli BW2952 7952445 YP_002927915.1 CDS yghA NC_012759.1 3034832 3035716 D MG1655 equivalent: b3003; oxidoreductase 3034832..3035716 Escherichia coli BW2952 7952682 YP_002927916.1 CDS exbD NC_012759.1 3035988 3036413 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD complement(3035988..3036413) Escherichia coli BW2952 7954929 YP_002927917.1 CDS exbB NC_012759.1 3036420 3037154 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB complement(3036420..3037154) Escherichia coli BW2952 7954235 YP_002927918.1 CDS metC NC_012759.1 3037406 3038593 D catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3037406..3038593 Escherichia coli BW2952 7954236 YP_002927919.1 CDS yghB NC_012759.1 3038733 3039392 D MG1655 equivalent: b3009; hypothetical protein 3038733..3039392 Escherichia coli BW2952 7953179 YP_002927920.1 CDS yqhC NC_012759.1 3039432 3040388 R MG1655 equivalent: b3010; putative DNA-binding transcriptional regulator complement(3039432..3040388) Escherichia coli BW2952 7952719 YP_002927921.1 CDS yqhD NC_012759.1 3040525 3041688 D MG1655 equivalent: b3011; alcohol dehydrogenase 3040525..3041688 Escherichia coli BW2952 7954777 YP_002927922.1 CDS dkgA NC_012759.1 3041793 3042620 D methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 3041793..3042620 Escherichia coli BW2952 7952442 YP_002927923.1 CDS yqhG NC_012759.1 3042820 3043746 D MG1655 equivalent: b3013; hypothetical protein 3042820..3043746 Escherichia coli BW2952 7952238 YP_002927924.1 CDS yqhH NC_012759.1 3043797 3044054 D MG1655 equivalent: b3014; putative outer membrane lipoprotein 3043797..3044054 Escherichia coli BW2952 7953011 YP_002927925.1 CDS ygiQ NC_012759.1 3044097 3046316 R MG1655 equivalent: b4469; hypothetical protein complement(3044097..3046316) Escherichia coli BW2952 7955204 YP_002927926.1 CDS ftsP NC_012759.1 3046427 3047839 R MG1655 equivalent: b3017; repressor protein for FtsI complement(3046427..3047839) Escherichia coli BW2952 7952909 YP_002927927.1 CDS plsC NC_012759.1 3047914 3048651 R MG1655 equivalent: b3018; 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(3047914..3048651) Escherichia coli BW2952 7955942 YP_002927928.1 CDS parC NC_012759.1 3048885 3051143 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A complement(3048885..3051143) Escherichia coli BW2952 7952226 YP_002927929.1 CDS ygiS NC_012759.1 3051281 3052888 R YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system; putative binding protein complement(3051281..3052888) Escherichia coli BW2952 7953335 YP_002927930.1 CDS ygiT NC_012759.1 3053021 3053416 R MG1655 equivalent: b3021; putative DNA-binding transcriptional regulator complement(3053021..3053416) Escherichia coli BW2952 7955736 YP_002927931.1 CDS mqsR NC_012759.1 3053418 3053714 R MG1655 equivalent: b3022; putative cyanide hydratase complement(3053418..3053714) Escherichia coli BW2952 7954778 YP_002927932.1 CDS ygiV NC_012759.1 3053919 3054401 R MG1655 equivalent: b3023; putative transcriptional regulator complement(3053919..3054401) Escherichia coli BW2952 7954705 YP_002927933.1 CDS ygiW NC_012759.1 3054454 3054846 R MG1655 equivalent: b3024; hypothetical protein complement(3054454..3054846) Escherichia coli BW2952 7955629 YP_002927934.1 CDS qseB NC_012759.1 3054998 3055657 D response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 3054998..3055657 Escherichia coli BW2952 7952867 YP_002927935.1 CDS qseC NC_012759.1 3055654 3057003 D MG1655 equivalent: b3026; sensor protein QseC 3055654..3057003 Escherichia coli BW2952 7953359 YP_002927936.1 CDS ygiZ NC_012759.1 3057049 3057381 R MG1655 equivalent: b3027; hypothetical protein complement(3057049..3057381) Escherichia coli BW2952 7956024 YP_002927937.1 CDS mdaB NC_012759.1 3057700 3058281 D MG1655 equivalent: b3028; NADPH quinone reductase 3057700..3058281 Escherichia coli BW2952 7952683 YP_002927938.1 CDS ygiN NC_012759.1 3058312 3058626 D MG1655 equivalent: b3029; quinol monooxygenase 3058312..3058626 Escherichia coli BW2952 7954370 YP_002927939.1 CDS parE NC_012759.1 3058674 3060566 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(3058674..3060566) Escherichia coli BW2952 7955885 YP_002927940.1 CDS yqiA NC_012759.1 3060595 3061176 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YqiA complement(3060595..3061176) Escherichia coli BW2952 7953336 YP_002927941.1 CDS cpdA NC_012759.1 3061176 3062003 R MG1655 equivalent: b3032; cyclic 3',5'-adenosine monophosphate phosphodiesterase complement(3061176..3062003) Escherichia coli BW2952 7954862 YP_002927942.1 CDS yqiB NC_012759.1 3062028 3062450 R MG1655 equivalent: b3033; hypothetical protein complement(3062028..3062450) Escherichia coli BW2952 7953177 YP_002927943.1 CDS nudF NC_012759.1 3062451 3063080 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase NudF complement(3062451..3063080) Escherichia coli BW2952 7954712 YP_002927944.1 CDS tolC NC_012759.1 3063285 3064766 D trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 3063285..3064766 Escherichia coli BW2952 7952433 YP_002927945.1 CDS ygiB NC_012759.1 3064914 3065585 D MG1655 equivalent: b3037; hypothetical protein 3064914..3065585 Escherichia coli BW2952 7956179 YP_002927946.1 CDS ygiC NC_012759.1 3065591 3066751 D MG1655 equivalent: b3038; putative enzyme 3065591..3066751 Escherichia coli BW2952 7952751 YP_002927947.1 CDS ygiD NC_012759.1 3066789 3067604 R seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein complement(3066789..3067604) Escherichia coli BW2952 7954848 YP_002927948.1 CDS zupT NC_012759.1 3067720 3068493 D MG1655 equivalent: b3040; zinc transporter ZupT 3067720..3068493 Escherichia coli BW2952 7954735 YP_002927949.1 CDS ribB NC_012759.1 3068983 3069636 R DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase complement(3068983..3069636) Escherichia coli BW2952 7956284 YP_002927950.1 CDS yqiC NC_012759.1 3070010 3070300 D MG1655 equivalent: b3042; hypothetical protein 3070010..3070300 Escherichia coli BW2952 7952271 YP_002927951.1 CDS ygiL NC_012759.1 3070584 3071135 D MG1655 equivalent: b3043; putative fimbrial protein 3070584..3071135 Escherichia coli BW2952 7953012 YP_002927952.1 CDS insC NC_012759.1 3071357 3071722 D IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 3071357..3071722 Escherichia coli BW2952 7954899 YP_002927953.1 CDS insD NC_012759.1 3071680 3072585 D IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 3071680..3072585 Escherichia coli BW2952 7954075 YP_002927954.1 CDS yqiH NC_012759.1 3075051 3075800 D MG1655 equivalent: b3047; putative periplasmic pilin chaperone 3075051..3075800 Escherichia coli BW2952 7954081 YP_002927955.1 CDS yqiI NC_012759.1 3075802 3076866 D MG1655 equivalent: b3048; hypothetical protein 3075802..3076866 Escherichia coli BW2952 7955303 YP_002927956.1 CDS glgS NC_012759.1 3076909 3077109 R Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS complement(3076909..3077109) Escherichia coli BW2952 7953013 YP_002927957.1 CDS yqiJ NC_012759.1 3077378 3078007 D MG1655 equivalent: b3050; putative inner membrane protein 3077378..3078007 Escherichia coli BW2952 7954930 YP_002927958.1 CDS yqiK NC_012759.1 3078034 3079695 D MG1655 equivalent: b3051; hypothetical protein 3078034..3079695 Escherichia coli BW2952 7955063 YP_002927959.1 CDS rfaE NC_012759.1 3080490 3081923 R catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase complement(3080490..3081923) Escherichia coli BW2952 7952094 YP_002927960.1 CDS glnE NC_012759.1 3081971 3084811 R catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase complement(3081971..3084811) Escherichia coli BW2952 7953686 YP_002927961.1 CDS ygiF NC_012759.1 3084834 3086135 R MG1655 equivalent: b3054; putative adenylate cyclase complement(3084834..3086135) Escherichia coli BW2952 7953671 YP_002927962.1 CDS htrG NC_012759.1 3086377 3086997 D MG1655 equivalent: b3055; putative signal transduction protein 3086377..3086997 Escherichia coli BW2952 7954623 YP_002927963.1 CDS cca NC_012759.1 3087061 3088299 D catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 3087061..3088299 Escherichia coli BW2952 7955593 YP_002927964.1 CDS bacA NC_012759.1 3088480 3089301 R BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase complement(3088480..3089301) Escherichia coli BW2952 7953750 YP_002927965.1 CDS folB NC_012759.1 3089391 3089759 R catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase complement(3089391..3089759) Escherichia coli BW2952 7956249 YP_002927966.1 CDS ygiH NC_012759.1 3089864 3090481 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY 3089864..3090481 Escherichia coli BW2952 7952565 YP_002927967.1 CDS ttdR NC_012759.1 3090494 3091426 R activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR complement(3090494..3091426) Escherichia coli BW2952 7952720 YP_002927968.1 CDS ttdA NC_012759.1 3091633 3092544 D Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 3091633..3092544 Escherichia coli BW2952 7954779 YP_002927969.1 CDS ttdB NC_012759.1 3092541 3093146 D Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 3092541..3093146 Escherichia coli BW2952 7954174 YP_002927970.1 CDS ttdT NC_012759.1 3093194 3094657 D MG1655 equivalent: b3063; putative tartrate:succinate antiporter 3093194..3094657 Escherichia coli BW2952 7954175 YP_002927971.1 CDS ygjD NC_012759.1 3094700 3095713 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease complement(3094700..3095713) Escherichia coli BW2952 7955618 YP_002927972.1 CDS rpsU NC_012759.1 3095951 3096166 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 3095951..3096166 Escherichia coli BW2952 7955277 YP_002927973.1 CDS dnaG NC_012759.1 3096277 3098022 D synthesizes RNA primers at the replication forks; DNA primase 3096277..3098022 Escherichia coli BW2952 7952285 YP_002927974.1 CDS rpoD NC_012759.1 3098217 3100058 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 3098217..3100058 Escherichia coli BW2952 7953330 YP_002927975.1 CDS mug NC_012759.1 3100137 3100643 R MG1655 equivalent: b3068; G/U mismatch-specific DNA glycosylase complement(3100137..3100643) Escherichia coli BW2952 7955991 YP_002927976.1 CDS yqjH NC_012759.1 3100897 3101661 R MG1655 equivalent: b3070; putative siderophore interacting protein complement(3100897..3101661) Escherichia coli BW2952 7952146 YP_002927977.1 CDS yqjI NC_012759.1 3101949 3102572 D MG1655 equivalent: b3071; putative transcriptional regulator 3101949..3102572 Escherichia coli BW2952 7955591 YP_002927978.1 CDS aer NC_012759.1 3102726 3104246 R MG1655 equivalent: b3072; fused signal transducer for aerotaxis sensory component/methyl accepting chemotaxis component complement(3102726..3104246) Escherichia coli BW2952 7955636 YP_002927979.1 CDS ygjG NC_012759.1 3104664 3106043 D catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 3104664..3106043 Escherichia coli BW2952 7953743 YP_002927980.1 CDS ygjH NC_012759.1 3106085 3106417 R MG1655 equivalent: b3074; hypothetical protein complement(3106085..3106417) Escherichia coli BW2952 7955833 YP_002927981.1 CDS ebgR NC_012759.1 3106636 3107619 D MG1655 equivalent: b3075; DNA-binding transcriptional repressor EbgR 3106636..3107619 Escherichia coli BW2952 7952868 YP_002927982.1 CDS ebgA NC_012759.1 3107803 3110895 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 3107803..3110895 Escherichia coli BW2952 7953466 YP_002927983.1 CDS ebgC NC_012759.1 3110892 3111341 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 3110892..3111341 Escherichia coli BW2952 7953168 YP_002927984.1 CDS ygjI NC_012759.1 3111404 3112837 D MG1655 equivalent: b3078; putative transporter 3111404..3112837 Escherichia coli BW2952 7953169 YP_002927985.1 CDS ygjJ NC_012759.1 3112971 3114041 D MG1655 equivalent: b3079; hypothetical protein 3112971..3114041 Escherichia coli BW2952 7955702 YP_002927986.1 CDS ygjK NC_012759.1 3114058 3116409 D MG1655 equivalent: b3080; putative glycosyl hydrolase 3114058..3116409 Escherichia coli BW2952 7953015 YP_002927987.1 CDS fadH NC_012759.1 3116835 3118853 D MG1655 equivalent: b3081; 2,4-dienoyl-CoA reductase 3116835..3118853 Escherichia coli BW2952 7954931 YP_002927988.1 CDS ygjM NC_012759.1 3118898 3119314 R MG1655 equivalent: b3082; putative DNA-binding transcriptional regulator complement(3118898..3119314) Escherichia coli BW2952 7952237 YP_002927989.1 CDS ygjN NC_012759.1 3119311 3119625 R MG1655 equivalent: b3083; hypothetical protein complement(3119311..3119625) Escherichia coli BW2952 7954780 YP_002927990.1 CDS rlmG NC_012759.1 3119909 3121045 R MG1655 equivalent: b3084; putative methyltransferase small domain protein complement(3119909..3121045) Escherichia coli BW2952 7952869 YP_002927991.1 CDS ygjP NC_012759.1 3121130 3121633 D MG1655 equivalent: b3085; putative metal dependent hydrolase 3121130..3121633 Escherichia coli BW2952 7955162 YP_002927992.1 CDS ygjQ NC_012759.1 3121710 3122402 D MG1655 equivalent: b3086; putative thioredoxin-like protein 3121710..3122402 Escherichia coli BW2952 7955145 YP_002927993.1 CDS ygjR NC_012759.1 3122481 3123467 D MG1655 equivalent: b3087; putative NAD(P)-binding dehydrogenase 3122481..3123467 Escherichia coli BW2952 7955622 YP_002927994.1 CDS alx NC_012759.1 3123750 3124715 D MG1655 equivalent: b3088; putative inner membrane protein, part of terminus 3123750..3124715 Escherichia coli BW2952 7952193 YP_002927995.1 CDS sstT NC_012759.1 3125114 3126358 D involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 3125114..3126358 Escherichia coli BW2952 7955078 YP_002927996.1 CDS ygjV NC_012759.1 3126363 3126914 R MG1655 equivalent: b3090; hypothetical protein complement(3126363..3126914) Escherichia coli BW2952 7956056 YP_002927997.1 CDS uxaA NC_012759.1 3126997 3128484 R MG1655 equivalent: b3091; altronate hydrolase complement(3126997..3128484) Escherichia coli BW2952 7952684 YP_002927998.1 CDS uxaC NC_012759.1 3128499 3129911 R catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase complement(3128499..3129911) Escherichia coli BW2952 7952461 YP_002927999.1 CDS exuT NC_012759.1 3130274 3131692 D MG1655 equivalent: b3093; hexuronate transporter 3130274..3131692 Escherichia coli BW2952 7956266 YP_002928000.1 CDS exuR NC_012759.1 3131822 3132598 D regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 3131822..3132598 Escherichia coli BW2952 7953906 YP_002928001.1 CDS yqjA NC_012759.1 3132943 3133605 D MG1655 equivalent: b3095; hypothetical protein 3132943..3133605 Escherichia coli BW2952 7953467 YP_002928002.1 CDS yqjB NC_012759.1 3133609 3133992 D MG1655 equivalent: b3096; hypothetical protein 3133609..3133992 Escherichia coli BW2952 7952721 YP_002928003.1 CDS yqjC NC_012759.1 3134139 3134507 D MG1655 equivalent: b3097; hypothetical protein 3134139..3134507 Escherichia coli BW2952 7953016 YP_002928004.1 CDS yqjD NC_012759.1 3134545 3134850 D MG1655 equivalent: b3098; hypothetical protein 3134545..3134850 Escherichia coli BW2952 7953017 YP_002928005.1 CDS yqjE NC_012759.1 3134853 3135257 D MG1655 equivalent: b3099; hypothetical protein 3134853..3135257 Escherichia coli BW2952 7953018 YP_002928006.1 CDS yqjK NC_012759.1 3135247 3135546 D MG1655 equivalent: b3100; hypothetical protein 3135247..3135546 Escherichia coli BW2952 7952722 YP_002928007.1 CDS yqjF NC_012759.1 3135732 3136124 D MG1655 equivalent: b3101; putative quinol oxidase subunit 3135732..3136124 Escherichia coli BW2952 7953019 YP_002928008.1 CDS yqjG NC_012759.1 3136194 3137180 D MG1655 equivalent: b3102; putative S-transferase 3136194..3137180 Escherichia coli BW2952 7955554 YP_002928009.1 CDS yhaH NC_012759.1 3137474 3137839 D MG1655 equivalent: b3103; putative inner membrane protein 3137474..3137839 Escherichia coli BW2952 7955599 YP_002928010.1 CDS yhaI NC_012759.1 3138081 3138437 D MG1655 equivalent: b3104; putative inner membrane protein 3138081..3138437 Escherichia coli BW2952 7955064 YP_002928011.1 CDS yhaJ NC_012759.1 3138488 3139384 R MG1655 equivalent: b3105; putative DNA-binding transcriptional regulator complement(3138488..3139384) Escherichia coli BW2952 7955065 YP_002928012.1 CDS yhaK NC_012759.1 3139489 3140190 D MG1655 equivalent: b3106; putative pirin-related protein 3139489..3140190 Escherichia coli BW2952 7954781 YP_002928013.1 CDS yhaL NC_012759.1 3140213 3140377 D MG1655 equivalent: b3107; hypothetical protein 3140213..3140377 Escherichia coli BW2952 7955323 YP_002928014.1 CDS yhaM NC_012759.1 3140511 3141821 R MG1655 equivalent: b4470; hypothetical protein complement(3140511..3141821) Escherichia coli BW2952 7955511 YP_002928015.1 CDS yhaO NC_012759.1 3141849 3143180 R MG1655 equivalent: b3110; putative transporter complement(3141849..3143180) Escherichia coli BW2952 7952910 YP_002928016.1 CDS tdcG NC_012759.1 3143455 3144819 R MG1655 equivalent: b4471; L-serine dehydratase 3 complement(3143455..3144819) Escherichia coli BW2952 7955665 YP_002928017.1 CDS tdcF NC_012759.1 3144891 3145280 R MG1655 equivalent: b3113; hypothetical protein complement(3144891..3145280) Escherichia coli BW2952 7954172 YP_002928018.1 CDS tdcE NC_012759.1 3145294 3147588 R MG1655 equivalent: b3114; pyruvate formate-lyase 4/2-ketobutyrate formate-lyase complement(3145294..3147588) Escherichia coli BW2952 7955124 YP_002928019.1 CDS tdcD NC_012759.1 3147622 3148830 R catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase complement(3147622..3148830) Escherichia coli BW2952 7955851 YP_002928020.1 CDS tdcC NC_012759.1 3148856 3150187 R involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC complement(3148856..3150187) Escherichia coli BW2952 7955773 YP_002928021.1 CDS tdcB NC_012759.1 3150209 3151198 R catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase complement(3150209..3151198) Escherichia coli BW2952 7954176 YP_002928022.1 CDS tdcA NC_012759.1 3151297 3152235 R regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA complement(3151297..3152235) Escherichia coli BW2952 7952610 YP_002928023.1 CDS tdcR NC_012759.1 3152550 3152768 D participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 3152550..3152768 Escherichia coli BW2952 7953370 YP_002928024.1 CDS yhaB NC_012759.1 3153024 3153563 D MG1655 equivalent: b3120; hypothetical protein 3153024..3153563 Escherichia coli BW2952 7953382 YP_002928025.1 CDS yhaC NC_012759.1 3153585 3154772 D MG1655 equivalent: b3121; hypothetical protein 3153585..3154772 Escherichia coli BW2952 7955512 YP_002928026.1 CDS garK NC_012759.1 3155795 3156940 R MG1655 equivalent: b3124; glycerate kinase complement(3155795..3156940) Escherichia coli BW2952 7952095 YP_002928027.1 CDS garR NC_012759.1 3157037 3157921 R catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase complement(3157037..3157921) Escherichia coli BW2952 7953843 YP_002928028.1 CDS garL NC_012759.1 3157957 3158727 R cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase complement(3157957..3158727) Escherichia coli BW2952 7956107 YP_002928029.1 CDS garP NC_012759.1 3158743 3160077 R MG1655 equivalent: b3127; putative (D)-galactarate transporter complement(3158743..3160077) Escherichia coli BW2952 7952456 YP_002928030.1 CDS garD NC_012759.1 3160452 3162023 D MG1655 equivalent: b3128; (D)-galactarate dehydrogenase 3160452..3162023 Escherichia coli BW2952 7954582 YP_002928031.1 CDS sohA NC_012759.1 3162172 3162507 D SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation; putative regulator PrlF 3162172..3162507 Escherichia coli BW2952 7952216 YP_002928032.1 CDS yhaV NC_012759.1 3162507 3162971 D MG1655 equivalent: b3130; hypothetical protein 3162507..3162971 Escherichia coli BW2952 7955561 YP_002928033.1 CDS agaR NC_012759.1 3163026 3163835 R transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR complement(3163026..3163835) Escherichia coli BW2952 7953020 YP_002928034.1 CDS kbaZ NC_012759.1 3164084 3165364 D MG1655 equivalent: b3132; tagatose 6-phosphate aldolase 1, kbaZ subunit 3164084..3165364 Escherichia coli BW2952 7953409 YP_002928035.1 CDS agaV NC_012759.1 3165387 3165860 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3165387..3165860 Escherichia coli BW2952 7956103 YP_002928036.1 CDS agaS NC_012759.1 3167146 3168300 D MG1655 equivalent: b3136; tagatose-6-phosphate ketose/aldose isomerase 3167146..3168300 Escherichia coli BW2952 7954336 YP_002928037.1 CDS kbaY NC_012759.1 3168313 3169173 D catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3168313..3169173 Escherichia coli BW2952 7956104 YP_002928038.1 CDS agaB NC_012759.1 3169340 3169816 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3169340..3169816 Escherichia coli BW2952 7956102 YP_002928039.1 CDS agaC NC_012759.1 3169855 3170658 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIC 3169855..3170658 Escherichia coli BW2952 7954337 YP_002928040.1 CDS agaD NC_012759.1 3170648 3171439 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID 3170648..3171439 Escherichia coli BW2952 7954338 YP_002928041.1 CDS agaI NC_012759.1 3171440 3172195 D MG1655 equivalent: b3141; galactosamine-6-phosphate isomerase 3171440..3172195 Escherichia coli BW2952 7954339 YP_002928042.1 CDS yraH NC_012759.1 3172596 3173180 D MG1655 equivalent: b3142; putative fimbrial-like adhesin protein 3172596..3173180 Escherichia coli BW2952 7953760 YP_002928043.1 CDS yraI NC_012759.1 3173260 3173955 D MG1655 equivalent: b3143; putative periplasmic pilin chaperone 3173260..3173955 Escherichia coli BW2952 7954900 YP_002928044.1 CDS yraJ NC_012759.1 3173984 3176500 D MG1655 equivalent: b3144; putative outer membrane protein 3173984..3176500 Escherichia coli BW2952 7955304 YP_002928045.1 CDS yraK NC_012759.1 3176511 3177602 D MG1655 equivalent: b3145; putative fimbrial-like adhesin protein 3176511..3177602 Escherichia coli BW2952 7955213 YP_002928046.1 CDS yraL NC_012759.1 3177645 3178505 R MG1655 equivalent: b3146; putative methyltransferase complement(3177645..3178505) Escherichia coli BW2952 7954901 YP_002928047.1 CDS yraM NC_012759.1 3178570 3180606 D MG1655 equivalent: b3147; hypothetical protein 3178570..3180606 Escherichia coli BW2952 7955156 YP_002928048.1 CDS yraN NC_012759.1 3180564 3180959 D MG1655 equivalent: b3148; hypothetical protein 3180564..3180959 Escherichia coli BW2952 7953021 YP_002928049.1 CDS diaA NC_012759.1 3180979 3181569 D Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 3180979..3181569 Escherichia coli BW2952 7953022 YP_002928050.1 CDS yraP NC_012759.1 3181579 3182154 D MG1655 equivalent: b3150; hypothetical protein 3181579..3182154 Escherichia coli BW2952 7953337 YP_002928051.1 CDS yraQ NC_012759.1 3182268 3183308 R MG1655 equivalent: b3151; putative permease complement(3182268..3183308) Escherichia coli BW2952 7955514 YP_002928052.1 CDS yraR NC_012759.1 3183381 3184016 R MG1655 equivalent: b3152; putative nucleoside-diphosphate-sugar epimerase complement(3183381..3184016) Escherichia coli BW2952 7955307 YP_002928053.1 CDS yhbO NC_012759.1 3184144 3184662 D MG1655 equivalent: b3153; putative intracellular protease 3184144..3184662 Escherichia coli BW2952 7955186 YP_002928054.1 CDS yhbP NC_012759.1 3184642 3185085 R MG1655 equivalent: b3154; hypothetical protein complement(3184642..3185085) Escherichia coli BW2952 7955080 YP_002928055.1 CDS yhbQ NC_012759.1 3185136 3185438 D MG1655 equivalent: b3155; GIY-YIG nuclease superfamily protein 3185136..3185438 Escherichia coli BW2952 7952870 YP_002928056.1 CDS yhbS NC_012759.1 3185425 3185928 R MG1655 equivalent: b3156; putative acyltransferase with acyl-CoA N-acyltransferase domain complement(3185425..3185928) Escherichia coli BW2952 7954835 YP_002928057.1 CDS yhbT NC_012759.1 3185922 3186446 R MG1655 equivalent: b3157; putative lipid carrier protein complement(3185922..3186446) Escherichia coli BW2952 7954618 YP_002928058.1 CDS yhbU NC_012759.1 3186655 3187650 D MG1655 equivalent: b3158; putative peptidase (collagenase-like) 3186655..3187650 Escherichia coli BW2952 7955101 YP_002928059.1 CDS yhbV NC_012759.1 3187659 3188537 D MG1655 equivalent: b3159; putative protease 3187659..3188537 Escherichia coli BW2952 7955287 YP_002928060.1 CDS yhbW NC_012759.1 3188618 3189625 D MG1655 equivalent: b3160; hypothetical protein 3188618..3189625 Escherichia coli BW2952 7955331 YP_002928061.1 CDS mtr NC_012759.1 3189743 3190987 R tryptophan transporter of high affinity; tryptophan permease complement(3189743..3190987) Escherichia coli BW2952 7954849 YP_002928062.1 CDS deaD NC_012759.1 3191141 3193030 R participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD complement(3191141..3193030) Escherichia coli BW2952 7956213 YP_002928063.1 CDS nlpI NC_012759.1 3193210 3194094 R lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI complement(3193210..3194094) Escherichia coli BW2952 7952534 YP_002928064.1 CDS pnp NC_012759.1 3194203 3196338 R MG1655 equivalent: b3164; polynucleotide phosphorylase/polyadenylase complement(3194203..3196338) Escherichia coli BW2952 7952871 YP_002928065.1 CDS rpsO NC_012759.1 3196585 3196854 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(3196585..3196854) Escherichia coli BW2952 7952194 YP_002928066.1 CDS truB NC_012759.1 3197003 3197947 R catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(3197003..3197947) Escherichia coli BW2952 7952278 YP_002928067.1 CDS rbfA NC_012759.1 3197947 3198348 R associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A complement(3197947..3198348) Escherichia coli BW2952 7956202 YP_002928068.1 CDS infB NC_012759.1 3198512 3201184 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(3198512..3201184) Escherichia coli BW2952 7952294 YP_002928069.1 CDS nusA NC_012759.1 3201209 3202696 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(3201209..3202696) Escherichia coli BW2952 7953736 YP_002928070.1 CDS yhbC NC_012759.1 3202724 3203182 R in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein complement(3202724..3203182) Escherichia coli BW2952 7956171 YP_002928071.1 CDS argG NC_012759.1 3203807 3205150 D catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 3203807..3205150 Escherichia coli BW2952 7952068 YP_002928072.1 CDS yhbX NC_012759.1 3205158 3206783 R MG1655 equivalent: b3173; putative hydrolase, inner membrane complement(3205158..3206783) Escherichia coli BW2952 7952502 YP_002928073.1 CDS secG NC_012759.1 3207343 3207675 R MG1655 equivalent: b3175; preprotein translocase subunit SecG complement(3207343..3207675) Escherichia coli BW2952 7952069 YP_002928074.1 CDS glmM NC_012759.1 3207903 3209240 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(3207903..3209240) Escherichia coli BW2952 7955760 YP_002928075.1 CDS folP NC_012759.1 3209233 3210081 R catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase complement(3209233..3210081) Escherichia coli BW2952 7954532 YP_002928076.1 CDS hflB NC_012759.1 3210171 3212105 R inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease complement(3210171..3212105) Escherichia coli BW2952 7952383 YP_002928077.1 CDS rrmJ NC_012759.1 3212205 3212834 R Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J complement(3212205..3212834) Escherichia coli BW2952 7955780 YP_002928078.1 CDS yhbY NC_012759.1 3212960 3213253 D RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 3212960..3213253 Escherichia coli BW2952 7952245 YP_002928079.1 CDS greA NC_012759.1 3213409 3213885 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(3213409..3213885) Escherichia coli BW2952 7955573 YP_002928080.1 CDS dacB NC_012759.1 3214133 3215566 D penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 3214133..3215566 Escherichia coli BW2952 7956167 YP_002928081.1 CDS obgE NC_012759.1 3215752 3216924 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(3215752..3216924) Escherichia coli BW2952 7953217 YP_002928082.1 CDS yhbE NC_012759.1 3216940 3217905 R MG1655 equivalent: b3184; hypothetical protein complement(3216940..3217905) Escherichia coli BW2952 7953879 YP_002928083.1 CDS rpmA NC_012759.1 3218032 3218289 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(3218032..3218289) Escherichia coli BW2952 7952685 YP_002928084.1 CDS rplU NC_012759.1 3218310 3218621 R MG1655 equivalent: b3186; 50S ribosomal protein L21 complement(3218310..3218621) Escherichia coli BW2952 7952354 YP_002928085.1 CDS ispB NC_012759.1 3218880 3219851 D MG1655 equivalent: b3187; octaprenyl diphosphate synthase 3218880..3219851 Escherichia coli BW2952 7952349 YP_002928086.1 CDS sfsB NC_012759.1 3220079 3220357 D activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 3220079..3220357 Escherichia coli BW2952 7954420 YP_002928087.1 CDS murA NC_012759.1 3220405 3221664 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(3220405..3221664) Escherichia coli BW2952 7953391 YP_002928088.1 CDS yrbA NC_012759.1 3221719 3221973 R MG1655 equivalent: b3190; putative DNA-binding transcriptional regulator complement(3221719..3221973) Escherichia coli BW2952 7956239 YP_002928089.1 CDS yrbB NC_012759.1 3222133 3222426 R MG1655 equivalent: b3191; hypothetical protein complement(3222133..3222426) Escherichia coli BW2952 7954782 YP_002928090.1 CDS yrbC NC_012759.1 3222426 3223061 R MG1655 equivalent: b3192; putative ABC-type organic solvent transporter complement(3222426..3223061) Escherichia coli BW2952 7955416 YP_002928091.1 CDS yrbD NC_012759.1 3223080 3223631 R MG1655 equivalent: b3193; putative ABC-type organic solvent transporter complement(3223080..3223631) Escherichia coli BW2952 7954599 YP_002928092.1 CDS yrbE NC_012759.1 3223636 3224418 R MG1655 equivalent: b3194; putative toluene transporter subunit: membrane component of ABC superfamily complement(3223636..3224418) Escherichia coli BW2952 7954600 YP_002928093.1 CDS yrbF NC_012759.1 3224426 3225235 R ATP-binding subunit of a putative ABC toluene efflux transporter; putative ABC transporter ATP-binding protein YrbF complement(3224426..3225235) Escherichia coli BW2952 7955625 YP_002928094.1 CDS yrbG NC_012759.1 3225445 3226422 D YrbG; inner membrane protein involved in cell envelope integrity; putative sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; putative calcium/sodium:proton antiporter 3225445..3226422 Escherichia coli BW2952 7955624 YP_002928095.1 CDS kdsD NC_012759.1 3226436 3227422 D MG1655 equivalent: b3197; D-arabinose 5-phosphate isomerase 3226436..3227422 Escherichia coli BW2952 7954673 YP_002928096.1 CDS kdsC NC_012759.1 3227443 3228009 D forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 3227443..3228009 Escherichia coli BW2952 7953227 YP_002928097.1 CDS yrbK NC_012759.1 3228006 3228581 D MG1655 equivalent: b3199; hypothetical protein 3228006..3228581 Escherichia coli BW2952 7952300 YP_002928098.1 CDS lptA NC_012759.1 3228550 3229107 D LptA; periplasmic binding protein part of a putative ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 3228550..3229107 Escherichia coli BW2952 7953023 YP_002928099.1 CDS lptB NC_012759.1 3229114 3229839 D MG1655 equivalent: b3201; putative ABC transporter ATP-binding protein YhbG 3229114..3229839 Escherichia coli BW2952 7955737 YP_002928100.1 CDS rpoN NC_012759.1 3229887 3231320 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 3229887..3231320 Escherichia coli BW2952 7955725 YP_002928101.1 CDS hpf NC_012759.1 3231343 3231630 D YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; putative sigma(54) modulation protein 3231343..3231630 Escherichia coli BW2952 7955990 YP_002928102.1 CDS ptsN NC_012759.1 3231748 3232239 D MG1655 equivalent: b3204; PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 3231748..3232239 Escherichia coli BW2952 7955571 YP_002928103.1 CDS yhbJ NC_012759.1 3232285 3233139 D MG1655 equivalent: b3205; hypothetical protein 3232285..3233139 Escherichia coli BW2952 7956087 YP_002928104.1 CDS npr NC_012759.1 3233136 3233408 D MG1655 equivalent: b3206; phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 3233136..3233408 Escherichia coli BW2952 7955546 YP_002928105.1 CDS yrbL NC_012759.1 3233622 3234254 D MG1655 equivalent: b3207; hypothetical protein 3233622..3234254 Escherichia coli BW2952 7954540 YP_002928106.1 CDS mtgA NC_012759.1 3234251 3234979 R glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase complement(3234251..3234979) Escherichia coli BW2952 7955515 YP_002928107.1 CDS elbB NC_012759.1 3234976 3235629 R MG1655 equivalent: b3209; isoprenoid biosynthesis protein with amidotransferase-like domain complement(3234976..3235629) Escherichia coli BW2952 7952580 YP_002928108.1 CDS arcB NC_012759.1 3235859 3238195 R sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB complement(3235859..3238195) Escherichia coli BW2952 7952195 YP_002928109.1 CDS yhcC NC_012759.1 3238291 3239220 R MG1655 equivalent: b3211; putative Fe-S oxidoreductase complement(3238291..3239220) Escherichia coli BW2952 7953928 YP_002928110.1 CDS gltB NC_012759.1 3239802 3244355 D catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 3239802..3244355 Escherichia coli BW2952 7954873 YP_002928111.1 CDS gltD NC_012759.1 3244368 3245786 D glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3244368..3245786 Escherichia coli BW2952 7953823 YP_002928112.1 CDS gltF NC_012759.1 3246346 3247110 D MG1655 equivalent: b3214; hypothetical protein 3246346..3247110 Escherichia coli BW2952 7953822 YP_002928113.1 CDS yhcA NC_012759.1 3247282 3247956 D member of the periplasmic pilus chaperone family of proteins; putative periplasmic chaperone protein 3247282..3247956 Escherichia coli BW2952 7954495 YP_002928114.1 CDS yhcD NC_012759.1 3247977 3250358 D MG1655 equivalent: b3216; putative outer membrane protein 3247977..3250358 Escherichia coli BW2952 7955298 YP_002928115.1 CDS insH NC_012759.1 3250872 3251888 R MG1655 equivalent: b3218; IS5 transposase and trans-activator complement(3250872..3251888) Escherichia coli BW2952 7955214 YP_002928116.1 CDS yhcF NC_012759.1 3252096 3252812 D MG1655 equivalent: b3219; putative transcriptional regulator 3252096..3252812 Escherichia coli BW2952 7954043 YP_002928117.1 CDS yhcG NC_012759.1 3252997 3254124 D MG1655 equivalent: b3220; hypothetical protein 3252997..3254124 Escherichia coli BW2952 7955637 YP_002928118.1 CDS yhcH NC_012759.1 3254184 3254648 R MG1655 equivalent: b3221; hypothetical protein complement(3254184..3254648) Escherichia coli BW2952 7953024 YP_002928119.1 CDS nanK NC_012759.1 3254645 3255520 R catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase complement(3254645..3255520) Escherichia coli BW2952 7952873 YP_002928120.1 CDS nanE NC_012759.1 3255517 3256206 R Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase complement(3255517..3256206) Escherichia coli BW2952 7955177 YP_002928121.1 CDS nanT NC_012759.1 3256254 3257744 R MG1655 equivalent: b3224; putative sialic acid transporter complement(3256254..3257744) Escherichia coli BW2952 7955178 YP_002928122.1 CDS nanA NC_012759.1 3257853 3258746 R catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase complement(3257853..3258746) Escherichia coli BW2952 7956042 YP_002928123.1 CDS nanR NC_012759.1 3258868 3259659 R Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR complement(3258868..3259659) Escherichia coli BW2952 7954346 YP_002928124.1 CDS dcuD NC_012759.1 3260039 3261406 D YhcL; uncharacterized member of the DcuC family of anaerobic dicarboxylate transporters; probable role in transport of carboxylates across the inner membrane from the periplasm; its encoding gene is not essential for growth and is probably cryptic; putative cryptic C4-dicarboxylate transporter DcuD 3260039..3261406 Escherichia coli BW2952 7953410 YP_002928125.1 CDS sspB NC_012759.1 3261449 3261946 R MG1655 equivalent: b3228; ClpXP protease specificity-enhancing factor complement(3261449..3261946) Escherichia coli BW2952 7955703 YP_002928126.1 CDS sspA NC_012759.1 3261952 3262590 R transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A complement(3261952..3262590) Escherichia coli BW2952 7952645 YP_002928127.1 CDS rpsI NC_012759.1 3262985 3263377 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(3262985..3263377) Escherichia coli BW2952 7956075 YP_002928128.1 CDS rplM NC_012759.1 3263393 3263821 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(3263393..3263821) Escherichia coli BW2952 7952293 YP_002928129.1 CDS yhcM NC_012759.1 3264040 3265167 R MG1655 equivalent: b3232; hypothetical protein complement(3264040..3265167) Escherichia coli BW2952 7952340 YP_002928130.1 CDS yhcB NC_012759.1 3265361 3265759 D MG1655 equivalent: b3233; cytochrome d ubiquinol oxidase subunit III 3265361..3265759 Escherichia coli BW2952 7953087 YP_002928131.1 CDS degQ NC_012759.1 3265913 3267280 D MG1655 equivalent: b3234; serine endoprotease 3265913..3267280 Escherichia coli BW2952 7953025 YP_002928132.1 CDS degS NC_012759.1 3267370 3268437 D MG1655 equivalent: b3235; serine endoprotease 3267370..3268437 Escherichia coli BW2952 7956030 YP_002928133.1 CDS mdh NC_012759.1 3268500 3269438 R oxidizes malate to oxaloacetate; malate dehydrogenase complement(3268500..3269438) Escherichia coli BW2952 7956031 YP_002928134.1 CDS argR NC_012759.1 3269873 3270343 D regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 3269873..3270343 Escherichia coli BW2952 7954199 YP_002928135.1 CDS yhcN NC_012759.1 3270708 3270971 D MG1655 equivalent: b3238; hypothetical protein 3270708..3270971 Escherichia coli BW2952 7953433 YP_002928136.1 CDS yhcO NC_012759.1 3271027 3271299 R MG1655 equivalent: b3239; putative barnase inhibitor complement(3271027..3271299) Escherichia coli BW2952 7953026 YP_002928137.1 CDS aaeB NC_012759.1 3271391 3273358 R with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB complement(3271391..3273358) Escherichia coli BW2952 7954666 YP_002928138.1 CDS aaeA NC_012759.1 3273364 3274296 R with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA complement(3273364..3274296) Escherichia coli BW2952 7954558 YP_002928139.1 CDS aaeX NC_012759.1 3274304 3274507 R membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein complement(3274304..3274507) Escherichia coli BW2952 7954559 YP_002928140.1 CDS aaeR NC_012759.1 3274690 3275619 D MG1655 equivalent: b3243; putative DNA-binding transcriptional regulator 3274690..3275619 Escherichia coli BW2952 7954229 YP_002928141.1 CDS tldD NC_012759.1 3275753 3277198 R responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD complement(3275753..3277198) Escherichia coli BW2952 7954823 YP_002928142.1 CDS yhdP NC_012759.1 3277628 3281428 R MG1655 equivalent: b4472; hypothetical protein complement(3277628..3281428) Escherichia coli BW2952 7955278 YP_002928143.1 CDS rng NC_012759.1 3281496 3282965 R involved in the processing of the 5'end of 16S rRNA; ribonuclease G complement(3281496..3282965) Escherichia coli BW2952 7952744 YP_002928144.1 CDS yhdE NC_012759.1 3282955 3283548 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(3282955..3283548) Escherichia coli BW2952 7955958 YP_002928145.1 CDS mreD NC_012759.1 3283557 3284045 R part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD complement(3283557..3284045) Escherichia coli BW2952 7952874 YP_002928146.1 CDS mreC NC_012759.1 3284045 3285148 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(3284045..3285148) Escherichia coli BW2952 7952621 YP_002928147.1 CDS mreB NC_012759.1 3285214 3286257 R functions in MreBCD complex in some organisms; rod shape-determining protein MreB complement(3285214..3286257) Escherichia coli BW2952 7952620 YP_002928148.1 CDS csrD NC_012759.1 3286562 3288502 R regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD complement(3286562..3288502) Escherichia coli BW2952 7952622 YP_002928149.1 CDS yhdH NC_012759.1 3288654 3289628 D MG1655 equivalent: b3253; putative oxidoreductase, Zn-dependent and NAD(P)-binding 3288654..3289628 Escherichia coli BW2952 7952686 YP_002928150.1 CDS accB NC_012759.1 3290606 3291076 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3290606..3291076 Escherichia coli BW2952 7955265 YP_002928151.1 CDS accC NC_012759.1 3291087 3292436 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 3291087..3292436 Escherichia coli BW2952 7952395 YP_002928152.1 CDS yhdT NC_012759.1 3292545 3292787 D MG1655 equivalent: b3257; hypothetical protein 3292545..3292787 Escherichia coli BW2952 7952400 YP_002928153.1 CDS panF NC_012759.1 3292777 3294228 D mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 3292777..3294228 Escherichia coli BW2952 7952723 YP_002928154.1 CDS prmA NC_012759.1 3294240 3295121 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 3294240..3295121 Escherichia coli BW2952 7954466 YP_002928155.1 CDS dusB NC_012759.1 3295450 3296415 D MG1655 equivalent: b3260; tRNA-dihydrouridine synthase B 3295450..3296415 Escherichia coli BW2952 7954252 YP_002928156.1 CDS fis NC_012759.1 3296441 3296737 D Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 3296441..3296737 Escherichia coli BW2952 7956205 YP_002928157.1 CDS yhdJ NC_012759.1 3296823 3297707 D MG1655 equivalent: b3262; putative methyltransferase 3296823..3297707 Escherichia coli BW2952 7953788 YP_002928158.1 CDS yhdU NC_012759.1 3297791 3297970 D MG1655 equivalent: b3263; hypothetical protein 3297791..3297970 Escherichia coli BW2952 7955160 YP_002928159.1 CDS envR NC_012759.1 3297973 3298635 R MG1655 equivalent: b3264; DNA-binding transcriptional regulator EnvR complement(3297973..3298635) Escherichia coli BW2952 7955141 YP_002928160.1 CDS acrE NC_012759.1 3299034 3300191 D MG1655 equivalent: b3265; hypothetical protein 3299034..3300191 Escherichia coli BW2952 7953440 YP_002928161.1 CDS acrF NC_012759.1 3300203 3303307 D MG1655 equivalent: b3266; multidrug efflux system protein 3300203..3303307 Escherichia coli BW2952 7953203 YP_002928162.1 CDS yhdV NC_012759.1 3303560 3303781 D MG1655 equivalent: b3267; putative outer membrane protein 3303560..3303781 Escherichia coli BW2952 7954304 YP_002928163.1 CDS yhdX NC_012759.1 3305304 3306485 D MG1655 equivalent: b3269; putative amino-acid transporter subunit 3305304..3306485 Escherichia coli BW2952 7955215 YP_002928164.1 CDS yhdY NC_012759.1 3306495 3307598 D MG1655 equivalent: b3270; putative amino-acid transporter subunit 3306495..3307598 Escherichia coli BW2952 7954642 YP_002928165.1 CDS yhdZ NC_012759.1 3307606 3308364 D MG1655 equivalent: b3271; putative amino-acid transporter subunit 3307606..3308364 Escherichia coli BW2952 7954643 YP_002928166.1 CDS yrdA NC_012759.1 3314415 3314969 D MG1655 equivalent: b3279; hypothetical protein 3314415..3314969 Escherichia coli BW2952 7952040 YP_002928167.1 CDS yrdB NC_012759.1 3314945 3315202 R MG1655 equivalent: b3280; hypothetical protein complement(3314945..3315202) Escherichia coli BW2952 7953027 YP_002928168.1 CDS aroE NC_012759.1 3315199 3316017 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(3315199..3316017) Escherichia coli BW2952 7952875 YP_002928169.1 CDS rimN NC_012759.1 3316022 3316594 R RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; putative ribosome maturation factor complement(3316022..3316594) Escherichia coli BW2952 7953232 YP_002928170.1 CDS yrdD NC_012759.1 3316599 3317141 R MG1655 equivalent: b3283; putative DNA topoisomerase complement(3316599..3317141) Escherichia coli BW2952 7955570 YP_002928171.1 CDS smg NC_012759.1 3317170 3317643 R MG1655 equivalent: b3284; hypothetical protein complement(3317170..3317643) Escherichia coli BW2952 7954737 YP_002928172.1 CDS smf NC_012759.1 3317615 3318739 R MG1655 equivalent: b4473; DNA protecting protein DprA complement(3317615..3318739) Escherichia coli BW2952 7952876 YP_002928173.1 CDS def NC_012759.1 3318869 3319378 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 3318869..3319378 Escherichia coli BW2952 7952911 YP_002928174.1 CDS fmt NC_012759.1 3319393 3320340 D modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 3319393..3320340 Escherichia coli BW2952 7954477 YP_002928175.1 CDS rsmB NC_012759.1 3320386 3321675 D catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase B 3320386..3321675 Escherichia coli BW2952 7952221 YP_002928176.1 CDS trkA NC_012759.1 3321697 3323073 D involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 3321697..3323073 Escherichia coli BW2952 7952223 YP_002928177.1 CDS mscL NC_012759.1 3323203 3323613 D forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3323203..3323613 Escherichia coli BW2952 7954353 YP_002928178.1 CDS yhdL NC_012759.1 3323610 3323828 R MG1655 equivalent: b4550; hypothetical protein complement(3323610..3323828) Escherichia coli BW2952 7954219 YP_002928179.1 CDS zntR NC_012759.1 3323884 3324309 R mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator complement(3323884..3324309) Escherichia coli BW2952 7952912 YP_002928180.1 CDS yhdN NC_012759.1 3324320 3324688 R MG1655 equivalent: b3293; hypothetical protein complement(3324320..3324688) Escherichia coli BW2952 7953385 YP_002928181.1 CDS rplQ NC_012759.1 3324795 3325178 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(3324795..3325178) Escherichia coli BW2952 7952877 YP_002928182.1 CDS rpoA NC_012759.1 3325219 3326208 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(3325219..3326208) Escherichia coli BW2952 7952344 YP_002928183.1 CDS rpsD NC_012759.1 3326234 3326854 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(3326234..3326854) Escherichia coli BW2952 7955983 YP_002928184.1 CDS rpsK NC_012759.1 3326888 3327277 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(3326888..3327277) Escherichia coli BW2952 7952288 YP_002928185.1 CDS rpsM NC_012759.1 3327294 3327650 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(3327294..3327650) Escherichia coli BW2952 7952274 YP_002928186.1 CDS rpmJ NC_012759.1 3327797 3327913 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 complement(3327797..3327913) Escherichia coli BW2952 7952276 YP_002928187.1 CDS secY NC_012759.1 3327945 3329276 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(3327945..3329276) Escherichia coli BW2952 7952364 YP_002928188.1 CDS rplO NC_012759.1 3329284 3329718 R late assembly protein; 50S ribosomal protein L15 complement(3329284..3329718) Escherichia coli BW2952 7955761 YP_002928189.1 CDS rpmD NC_012759.1 3329722 3329901 R L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 complement(3329722..3329901) Escherichia coli BW2952 7952342 YP_002928190.1 CDS rpsE NC_012759.1 3329905 3330408 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(3329905..3330408) Escherichia coli BW2952 7952358 YP_002928191.1 CDS rplR NC_012759.1 3330423 3330776 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(3330423..3330776) Escherichia coli BW2952 7952289 YP_002928192.1 CDS rplF NC_012759.1 3330786 3331319 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(3330786..3331319) Escherichia coli BW2952 7952345 YP_002928193.1 CDS rpsH NC_012759.1 3331332 3331724 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(3331332..3331724) Escherichia coli BW2952 7952367 YP_002928194.1 CDS rpsN NC_012759.1 3331758 3332063 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(3331758..3332063) Escherichia coli BW2952 7952292 YP_002928195.1 CDS rplE NC_012759.1 3332078 3332617 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(3332078..3332617) Escherichia coli BW2952 7952277 YP_002928196.1 CDS rplX NC_012759.1 3332632 3332946 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(3332632..3332946) Escherichia coli BW2952 7952366 YP_002928197.1 CDS rplN NC_012759.1 3332957 3333328 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(3332957..3333328) Escherichia coli BW2952 7952352 YP_002928198.1 CDS rpsQ NC_012759.1 3333493 3333747 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(3333493..3333747) Escherichia coli BW2952 7952341 YP_002928199.1 CDS rpmC NC_012759.1 3333747 3333938 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(3333747..3333938) Escherichia coli BW2952 7952280 YP_002928200.1 CDS rplP NC_012759.1 3333938 3334348 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(3333938..3334348) Escherichia coli BW2952 7952356 YP_002928201.1 CDS rpsC NC_012759.1 3334361 3335062 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(3334361..3335062) Escherichia coli BW2952 7952343 YP_002928202.1 CDS rplV NC_012759.1 3335080 3335412 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(3335080..3335412) Escherichia coli BW2952 7952287 YP_002928203.1 CDS rpsS NC_012759.1 3335427 3335705 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(3335427..3335705) Escherichia coli BW2952 7952350 YP_002928204.1 CDS rplB NC_012759.1 3335722 3336543 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(3335722..3336543) Escherichia coli BW2952 7952282 YP_002928205.1 CDS rplW NC_012759.1 3336561 3336863 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(3336561..3336863) Escherichia coli BW2952 7952347 YP_002928206.1 CDS rplD NC_012759.1 3336860 3337465 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(3336860..3337465) Escherichia coli BW2952 7952351 YP_002928207.1 CDS rplC NC_012759.1 3337476 3338105 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(3337476..3338105) Escherichia coli BW2952 7952365 YP_002928208.1 CDS rpsJ NC_012759.1 3338138 3338449 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(3338138..3338449) Escherichia coli BW2952 7952357 YP_002928209.1 CDS gspB NC_012759.1 3338687 3339106 R calcium-binding protein that may be required for the initiation of chromosome replication; chromosome replication protein PioO complement(3338687..3339106) Escherichia coli BW2952 7952273 YP_002928210.1 CDS gspA NC_012759.1 3339108 3340577 R MG1655 equivalent: b3323; general secretory pathway component, cryptic complement(3339108..3340577) Escherichia coli BW2952 7954470 YP_002928211.1 CDS gspC NC_012759.1 3340757 3341572 D MG1655 equivalent: b3324; general secretory pathway component, cryptic 3340757..3341572 Escherichia coli BW2952 7953778 YP_002928212.1 CDS gspD NC_012759.1 3341556 3343508 D MG1655 equivalent: b3325; general secretory pathway component, cryptic 3341556..3343508 Escherichia coli BW2952 7953779 YP_002928213.1 CDS gspE NC_012759.1 3343518 3344999 D MG1655 equivalent: b3326; general secretory pathway component, cryptic 3343518..3344999 Escherichia coli BW2952 7953780 YP_002928214.1 CDS gspF NC_012759.1 3344996 3346192 D MG1655 equivalent: b3327; general secretory pathway component, cryptic 3344996..3346192 Escherichia coli BW2952 7953781 YP_002928215.1 CDS gspG NC_012759.1 3346202 3346639 D MG1655 equivalent: b3328; pseudopilin, cryptic, general secretion pathway 3346202..3346639 Escherichia coli BW2952 7953782 YP_002928216.1 CDS gspH NC_012759.1 3346647 3347156 D MG1655 equivalent: b3329; putative general secretory pathway component, cryptic 3346647..3347156 Escherichia coli BW2952 7955818 YP_002928217.1 CDS gspI NC_012759.1 3347153 3347530 D MG1655 equivalent: b3330; general secretory pathway component, cryptic 3347153..3347530 Escherichia coli BW2952 7954915 YP_002928218.1 CDS gspJ NC_012759.1 3347523 3348110 D MG1655 equivalent: b3331; putative general secretory pathway component, cryptic 3347523..3348110 Escherichia coli BW2952 7953783 YP_002928219.1 CDS gspK NC_012759.1 3348103 3349086 D MG1655 equivalent: b3332; general secretory pathway component, cryptic 3348103..3349086 Escherichia coli BW2952 7954916 YP_002928220.1 CDS gspL NC_012759.1 3349101 3350264 D MG1655 equivalent: b3333; general secretory pathway component, cryptic 3349101..3350264 Escherichia coli BW2952 7953784 YP_002928221.1 CDS gspM NC_012759.1 3350261 3350722 D MG1655 equivalent: b3334; general secretory pathway component, cryptic 3350261..3350722 Escherichia coli BW2952 7953785 YP_002928222.1 CDS gspO NC_012759.1 3350722 3351399 D MG1655 equivalent: b3335; bifunctional prepilin leader peptidase/ methylase 3350722..3351399 Escherichia coli BW2952 7953786 YP_002928223.1 CDS bfr NC_012759.1 3351428 3351904 R iron storage protein; bacterioferritin complement(3351428..3351904) Escherichia coli BW2952 7952572 YP_002928224.1 CDS bfd NC_012759.1 3351976 3352170 R MG1655 equivalent: b3337; bacterioferritin-associated ferredoxin complement(3351976..3352170) Escherichia coli BW2952 7952541 YP_002928225.1 CDS chiA NC_012759.1 3352339 3355032 R MG1655 equivalent: b3338; periplasmic endochitinase complement(3352339..3355032) Escherichia coli BW2952 7952542 YP_002928226.1 CDS tufA NC_012759.1 3355324 3356508 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(3355324..3356508) Escherichia coli BW2952 7954490 YP_002928227.1 CDS fusA NC_012759.1 3356579 3358693 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(3356579..3358693) Escherichia coli BW2952 7955788 YP_002928228.1 CDS rpsG NC_012759.1 3358721 3359260 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(3358721..3359260) Escherichia coli BW2952 7955785 YP_002928229.1 CDS rpsL NC_012759.1 3359357 3359731 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(3359357..3359731) Escherichia coli BW2952 7952291 YP_002928230.1 CDS yheL NC_012759.1 3359857 3360144 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB complement(3359857..3360144) Escherichia coli BW2952 7952275 YP_002928231.1 CDS yheM NC_012759.1 3360152 3360511 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC complement(3360152..3360511) Escherichia coli BW2952 7955081 YP_002928232.1 CDS yheN NC_012759.1 3360511 3360897 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD complement(3360511..3360897) Escherichia coli BW2952 7955083 YP_002928233.1 CDS yheO NC_012759.1 3360897 3361619 R MG1655 equivalent: b3346; putative DNA-binding transcriptional regulator complement(3360897..3361619) Escherichia coli BW2952 7955082 YP_002928234.1 CDS fkpA NC_012759.1 3361786 3362598 R rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase complement(3361786..3362598) Escherichia coli BW2952 7954783 YP_002928235.1 CDS slyX NC_012759.1 3362819 3363037 D MG1655 equivalent: b3348; hypothetical protein 3362819..3363037 Escherichia coli BW2952 7953579 YP_002928236.1 CDS slyD NC_012759.1 3363086 3363676 R rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase complement(3363086..3363676) Escherichia coli BW2952 7953028 YP_002928237.1 CDS yheV NC_012759.1 3363771 3363971 R MG1655 equivalent: b4551; hypothetical protein complement(3363771..3363971) Escherichia coli BW2952 7953578 YP_002928238.1 CDS kefB NC_012759.1 3363981 3365786 R involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB complement(3363981..3365786) Escherichia coli BW2952 7955435 YP_002928239.1 CDS kefG NC_012759.1 3365786 3366340 R required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG complement(3365786..3366340) Escherichia coli BW2952 7954578 YP_002928240.1 CDS yheS NC_012759.1 3366468 3368381 D MG1655 equivalent: b3352; putative ABC transporter ATP-binding protein 3366468..3368381 Escherichia coli BW2952 7952656 YP_002928241.1 CDS yheT NC_012759.1 3368381 3369403 D MG1655 equivalent: b3353; putative hydrolase 3368381..3369403 Escherichia coli BW2952 7953734 YP_002928242.1 CDS yheU NC_012759.1 3369397 3369615 D MG1655 equivalent: b3354; hypothetical protein 3369397..3369615 Escherichia coli BW2952 7954969 YP_002928243.1 CDS prkB NC_012759.1 3369669 3370538 D MG1655 equivalent: b3355; putative phosphoribulokinase 3369669..3370538 Escherichia coli BW2952 7953029 YP_002928244.1 CDS yhfA NC_012759.1 3370593 3370997 R MG1655 equivalent: b3356; hypothetical protein complement(3370593..3370997) Escherichia coli BW2952 7955318 YP_002928245.1 CDS crp NC_012759.1 3371299 3371931 D complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 3371299..3371931 Escherichia coli BW2952 7952878 YP_002928246.1 CDS yhfK NC_012759.1 3371970 3374072 D MG1655 equivalent: b3358; hypothetical protein 3371970..3374072 Escherichia coli BW2952 7953423 YP_002928247.1 CDS argD NC_012759.1 3374139 3375359 R DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein complement(3374139..3375359) Escherichia coli BW2952 7952724 YP_002928248.1 CDS pabA NC_012759.1 3375445 3376008 R aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II complement(3375445..3376008) Escherichia coli BW2952 7952560 YP_002928249.1 CDS fic NC_012759.1 3376040 3376642 R MG1655 equivalent: b3361; cell filamentation protein Fic complement(3376040..3376642) Escherichia coli BW2952 7952466 YP_002928250.1 CDS yhfG NC_012759.1 3376632 3376799 R MG1655 equivalent: b3362; hypothetical protein complement(3376632..3376799) Escherichia coli BW2952 7956068 YP_002928251.1 CDS ppiA NC_012759.1 3376904 3377476 R MG1655 equivalent: b3363; peptidyl-prolyl cis-trans isomerase A complement(3376904..3377476) Escherichia coli BW2952 7955417 YP_002928252.1 CDS tsgA NC_012759.1 3377747 3378928 D MG1655 equivalent: b3364; hypothetical protein 3377747..3378928 Escherichia coli BW2952 7954482 YP_002928253.1 CDS nirB NC_012759.1 3379190 3381733 D MG1655 equivalent: b3365; nitrite reductase, large subunit, NAD(P)H-binding 3379190..3381733 Escherichia coli BW2952 7955704 YP_002928254.1 CDS nirD NC_012759.1 3381730 3382056 D involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 3381730..3382056 Escherichia coli BW2952 7954401 YP_002928255.1 CDS nirC NC_012759.1 3382182 3382988 D member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 3382182..3382988 Escherichia coli BW2952 7954402 YP_002928256.1 CDS cysG NC_012759.1 3383007 3384380 D multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 3383007..3384380 Escherichia coli BW2952 7954403 YP_002928257.1 CDS yhfL NC_012759.1 3384627 3384794 D MG1655 equivalent: b3369; hypothetical protein 3384627..3384794 Escherichia coli BW2952 7953744 YP_002928258.1 CDS frlA NC_012759.1 3385089 3386426 D inner membrane protein possibly involved in fructoselysine transport; member of the flr operon; putative fructoselysine transporter 3385089..3386426 Escherichia coli BW2952 7953094 YP_002928259.1 CDS frlB NC_012759.1 3386447 3387469 D catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine; fructoselysine-6-P-deglycase 3386447..3387469 Escherichia coli BW2952 7954913 YP_002928260.1 CDS frlC NC_012759.1 3387519 3388349 D YhfOP; YhfP; YhfO; FrlC; catalyzes the interconversion of fructoselysine and psicoselysine; fructoselysine 3-epimerase 3387519..3388349 Escherichia coli BW2952 7953640 YP_002928261.1 CDS frlD NC_012759.1 3388346 3389131 D MG1655 equivalent: b3374; fructoselysine 6-kinase 3388346..3389131 Escherichia coli BW2952 7955090 YP_002928262.1 CDS frlR NC_012759.1 3389231 3389962 D may act as a transcriptional regulator of a putative fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes; DNA-binding transcriptional regulator FrlR 3389231..3389962 Escherichia coli BW2952 7953639 YP_002928263.1 CDS yhfS NC_012759.1 3390114 3391199 R MG1655 equivalent: b3376; hypothetical protein complement(3390114..3391199) Escherichia coli BW2952 7954809 YP_002928264.1 CDS yhfT NC_012759.1 3391211 3392515 R MG1655 equivalent: b3377; putative inner membrane protein complement(3391211..3392515) Escherichia coli BW2952 7952879 YP_002928265.1 CDS yhfU NC_012759.1 3392527 3392880 R MG1655 equivalent: b3378; hypothetical protein complement(3392527..3392880) Escherichia coli BW2952 7955010 YP_002928266.1 CDS php NC_012759.1 3392891 3393769 R phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE); putative hydrolase complement(3392891..3393769) Escherichia coli BW2952 7955418 YP_002928267.1 CDS yhfW NC_012759.1 3393766 3394992 R MG1655 equivalent: b3380; putative mutase complement(3393766..3394992) Escherichia coli BW2952 7954960 YP_002928268.1 CDS yhfX NC_012759.1 3394992 3396155 R MG1655 equivalent: b3381; putative amino acid racemase complement(3394992..3396155) Escherichia coli BW2952 7955176 YP_002928269.1 CDS yhfY NC_012759.1 3396239 3396601 R MG1655 equivalent: b3382; hypothetical protein complement(3396239..3396601) Escherichia coli BW2952 7954640 YP_002928270.1 CDS yhfZ NC_012759.1 3396618 3397523 R MG1655 equivalent: b3383; hypothetical protein complement(3396618..3397523) Escherichia coli BW2952 7952880 YP_002928271.1 CDS trpS NC_012759.1 3397813 3398817 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(3397813..3398817) Escherichia coli BW2952 7952881 YP_002928272.1 CDS gph NC_012759.1 3398810 3399568 R catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase complement(3398810..3399568) Escherichia coli BW2952 7956217 YP_002928273.1 CDS rpe NC_012759.1 3399561 3400238 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(3399561..3400238) Escherichia coli BW2952 7954538 YP_002928274.1 CDS dam NC_012759.1 3400256 3401092 R MG1655 equivalent: b3387; DNA adenine methylase complement(3400256..3401092) Escherichia coli BW2952 7953495 YP_002928275.1 CDS damX NC_012759.1 3401199 3402485 R MG1655 equivalent: b3388; hypothetical protein complement(3401199..3402485) Escherichia coli BW2952 7953298 YP_002928276.1 CDS aroB NC_012759.1 3402577 3403665 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(3402577..3403665) Escherichia coli BW2952 7955419 YP_002928277.1 CDS aroK NC_012759.1 3403722 3404243 R type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I complement(3403722..3404243) Escherichia coli BW2952 7952296 YP_002928278.1 CDS hofQ NC_012759.1 3404644 3405882 R outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ complement(3404644..3405882) Escherichia coli BW2952 7956037 YP_002928279.1 CDS hofP NC_012759.1 3405794 3406198 R MG1655 equivalent: b3392; hypothetical protein complement(3405794..3406198) Escherichia coli BW2952 7954875 YP_002928280.1 CDS hofO NC_012759.1 3406188 3406628 R MG1655 equivalent: b3393; hypothetical protein complement(3406188..3406628) Escherichia coli BW2952 7955420 YP_002928281.1 CDS hofN NC_012759.1 3406612 3407151 R MG1655 equivalent: b3394; putative fimbrial assembly protein complement(3406612..3407151) Escherichia coli BW2952 7952743 YP_002928282.1 CDS hofM NC_012759.1 3407151 3407930 R MG1655 equivalent: b3395; putative pilus assembly protein complement(3407151..3407930) Escherichia coli BW2952 7954874 YP_002928283.1 CDS mrcA NC_012759.1 3408050 3410602 D bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 3408050..3410602 Escherichia coli BW2952 7955322 YP_002928284.1 CDS nudE NC_012759.1 3410768 3411328 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE complement(3410768..3411328) Escherichia coli BW2952 7953705 YP_002928285.1 CDS yrfF NC_012759.1 3411648 3413783 D MG1655 equivalent: b3398; putative inner membrane protein 3411648..3413783 Escherichia coli BW2952 7952432 YP_002928286.1 CDS yrfG NC_012759.1 3413848 3414516 D MG1655 equivalent: b3399; putative hydrolase 3413848..3414516 Escherichia coli BW2952 7955066 YP_002928287.1 CDS hslR NC_012759.1 3414527 3414928 D MG1655 equivalent: b3400; ribosome-associated heat shock protein Hsp15 3414527..3414928 Escherichia coli BW2952 7954970 YP_002928288.1 CDS hslO NC_012759.1 3414953 3415831 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 3414953..3415831 Escherichia coli BW2952 7955980 YP_002928289.1 CDS yhgE NC_012759.1 3415894 3417618 R MG1655 equivalent: b3402; putative inner membrane protein complement(3415894..3417618) Escherichia coli BW2952 7953894 YP_002928290.1 CDS pck NC_012759.1 3417997 3419619 D PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 3417997..3419619 Escherichia coli BW2952 7955011 YP_002928291.1 CDS envZ NC_012759.1 3419695 3421047 R membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein complement(3419695..3421047) Escherichia coli BW2952 7954528 YP_002928292.1 CDS ompR NC_012759.1 3421044 3421763 R part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator complement(3421044..3421763) Escherichia coli BW2952 7956022 YP_002928293.1 CDS greB NC_012759.1 3421991 3422467 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 3421991..3422467 Escherichia coli BW2952 7953352 YP_002928294.1 CDS yhgF NC_012759.1 3422564 3424885 D MG1655 equivalent: b3407; putative transcriptional accessory protein 3422564..3424885 Escherichia coli BW2952 7956168 YP_002928295.1 CDS feoA NC_012759.1 3425342 3425569 D MG1655 equivalent: b3408; ferrous iron transport protein A 3425342..3425569 Escherichia coli BW2952 7955628 YP_002928296.1 CDS feoB NC_012759.1 3425586 3427907 D cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 3425586..3427907 Escherichia coli BW2952 7953574 YP_002928297.1 CDS feoC NC_012759.1 3427907 3428143 D MG1655 equivalent: b3410; putative DNA-binding transcriptional regulator 3427907..3428143 Escherichia coli BW2952 7953680 YP_002928298.1 CDS yhgA NC_012759.1 3428346 3429224 D MG1655 equivalent: b3411; hypothetical protein 3428346..3429224 Escherichia coli BW2952 7954810 YP_002928299.1 CDS bioH NC_012759.1 3429253 3430023 R Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH complement(3429253..3430023) Escherichia coli BW2952 7955741 YP_002928300.1 CDS gntX NC_012759.1 3430061 3430744 D involved in high-affinity gluconate transport; gluconate periplasmic binding protein 3430061..3430744 Escherichia coli BW2952 7952606 YP_002928301.1 CDS gntY NC_012759.1 3430803 3431378 D cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; putative DNA uptake protein 3430803..3431378 Escherichia coli BW2952 7953798 YP_002928302.1 CDS BWG_3106 NC_012759.1 3431849 3432214 D IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 3431849..3432214 Escherichia coli BW2952 7954918 YP_002928303.1 CDS BWG_3107 NC_012759.1 3432172 3432567 D insertion element IS2 transposase InsD 3432172..3432567 Escherichia coli BW2952 7954007 YP_002928304.1 CDS BWG_3108 NC_012759.1 3432536 3433078 D OSJNBa0065H10.1 protein 3432536..3433078 Escherichia coli BW2952 7954005 YP_002928305.1 CDS gntT NC_012759.1 3433063 3434391 D MG1655 equivalent: b3415; gluconate transporter, high-affinity GNT I system 3433063..3434391 Escherichia coli BW2952 7954433 YP_002928306.1 CDS malQ NC_012759.1 3434502 3436586 R amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase complement(3434502..3436586) Escherichia coli BW2952 7953799 YP_002928307.1 CDS malP NC_012759.1 3436596 3438989 R MG1655 equivalent: b3417; maltodextrin phosphorylase complement(3436596..3438989) Escherichia coli BW2952 7952327 YP_002928308.1 CDS malT NC_012759.1 3439601 3442306 D Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 3439601..3442306 Escherichia coli BW2952 7954204 YP_002928309.1 CDS rtcA NC_012759.1 3442349 3443365 R catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase complement(3442349..3443365) Escherichia coli BW2952 7953667 YP_002928310.1 CDS rtcB NC_012759.1 3443369 3444595 R MG1655 equivalent: b3421; hypothetical protein complement(3443369..3444595) Escherichia coli BW2952 7955981 YP_002928311.1 CDS rtcR NC_012759.1 3444784 3446382 D MG1655 equivalent: b3422; sigma 54-dependent transcriptional regulator of rtcBA expression 3444784..3446382 Escherichia coli BW2952 7952882 YP_002928312.1 CDS glpR NC_012759.1 3446364 3447122 R represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR complement(3446364..3447122) Escherichia coli BW2952 7956044 YP_002928313.1 CDS glpG NC_012759.1 3447139 3447969 R protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG complement(3447139..3447969) Escherichia coli BW2952 7953456 YP_002928314.1 CDS glpE NC_012759.1 3448014 3448340 R belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase complement(3448014..3448340) Escherichia coli BW2952 7955084 YP_002928315.1 CDS glpD NC_012759.1 3448530 3450035 D in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 3448530..3450035 Escherichia coli BW2952 7956138 YP_002928316.1 CDS glgP NC_012759.1 3450651 3453098 R MG1655 equivalent: b3428; glycogen phosphorylase complement(3450651..3453098) Escherichia coli BW2952 7956053 YP_002928317.1 CDS glgA NC_012759.1 3453117 3454550 R catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase complement(3453117..3454550) Escherichia coli BW2952 7953864 YP_002928318.1 CDS glgC NC_012759.1 3454550 3455845 R catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase complement(3454550..3455845) Escherichia coli BW2952 7953865 YP_002928319.1 CDS glgX NC_012759.1 3455863 3457836 R catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching protein complement(3455863..3457836) Escherichia coli BW2952 7953805 YP_002928320.1 CDS glgB NC_012759.1 3457833 3460019 R catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein complement(3457833..3460019) Escherichia coli BW2952 7953863 YP_002928321.1 CDS asd NC_012759.1 3460292 3461395 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(3460292..3461395) Escherichia coli BW2952 7952219 YP_002928322.1 CDS yhgN NC_012759.1 3461588 3462181 D YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); putative dITP- and XTP- hydrolase 3461588..3462181 Escherichia coli BW2952 7952515 YP_002928323.1 CDS gntU NC_012759.1 3462238 3463578 R MG1655 equivalent: b4476; low affinity gluconate transporter complement(3462238..3463578) Escherichia coli BW2952 7954648 YP_002928324.1 CDS gntK NC_012759.1 3463582 3464109 R thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase complement(3463582..3464109) Escherichia coli BW2952 7953800 YP_002928325.1 CDS gntR NC_012759.1 3464248 3465243 R MG1655 equivalent: b3438; DNA-binding transcriptional repressor complement(3464248..3465243) Escherichia coli BW2952 7953797 YP_002928326.1 CDS yhhW NC_012759.1 3465467 3466162 R MG1655 equivalent: b3439; hypothetical protein complement(3465467..3466162) Escherichia coli BW2952 7953457 YP_002928327.1 CDS yhhX NC_012759.1 3466285 3467322 R MG1655 equivalent: b3440; putative dehydrogenase complement(3466285..3467322) Escherichia coli BW2952 7955421 YP_002928328.1 CDS yhhY NC_012759.1 3467655 3468143 D YhhY; regulated by the fur regulator; unknown function; putative acetyltransferase YhhY 3467655..3468143 Escherichia coli BW2952 7952096 YP_002928329.1 CDS yhhZ NC_012759.1 3468380 3469558 D MG1655 equivalent: b3442; hypothetical protein 3468380..3469558 Escherichia coli BW2952 7954603 YP_002928330.1 CDS insA NC_012759.1 3470000 3470275 D MG1655 equivalent: b3444; KpLE2 phage-like element; IS1 repressor protein InsA 3470000..3470275 Escherichia coli BW2952 7953030 YP_002928331.1 CDS insB NC_012759.1 3470194 3470697 D MG1655 equivalent: b3445; IS1 transposase InsAB' 3470194..3470697 Escherichia coli BW2952 7954068 YP_002928332.1 CDS yrhD NC_012759.1 3470921 3471076 D MG1655 equivalent: b4612; hypothetical protein 3470921..3471076 Escherichia coli BW2952 7954022 YP_002928333.1 CDS yrhB NC_012759.1 3471276 3471560 D MG1655 equivalent: b3446; hypothetical protein 3471276..3471560 Escherichia coli BW2952 7953982 YP_002928334.1 CDS ggt NC_012759.1 3471598 3473340 R periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase complement(3471598..3473340) Escherichia coli BW2952 7955516 YP_002928335.1 CDS yhhA NC_012759.1 3473460 3473900 D MG1655 equivalent: b3448; hypothetical protein 3473460..3473900 Escherichia coli BW2952 7953772 YP_002928336.1 CDS ugpQ NC_012759.1 3473887 3474630 R hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; glycerophosphodiester phosphodiesterase complement(3473887..3474630) Escherichia coli BW2952 7953031 YP_002928337.1 CDS ugpC NC_012759.1 3474627 3475697 R part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit complement(3474627..3475697) Escherichia coli BW2952 7953854 YP_002928338.1 CDS ugpE NC_012759.1 3475699 3476544 R with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein complement(3475699..3476544) Escherichia coli BW2952 7953850 YP_002928339.1 CDS ugpA NC_012759.1 3476541 3477428 R with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease complement(3476541..3477428) Escherichia coli BW2952 7953851 YP_002928340.1 CDS ugpB NC_012759.1 3477526 3478842 R with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein complement(3477526..3478842) Escherichia coli BW2952 7953852 YP_002928341.1 CDS livF NC_012759.1 3479241 3479954 R with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(3479241..3479954) Escherichia coli BW2952 7953853 YP_002928342.1 CDS livG NC_012759.1 3479956 3480723 R Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(3479956..3480723) Escherichia coli BW2952 7954126 YP_002928343.1 CDS livM NC_012759.1 3480720 3481997 R Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit complement(3480720..3481997) Escherichia coli BW2952 7954127 YP_002928344.1 CDS livH NC_012759.1 3481994 3482920 R LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH complement(3481994..3482920) Escherichia coli BW2952 7954128 YP_002928345.1 CDS livK NC_012759.1 3482968 3484077 R MG1655 equivalent: b3458; leucine transporter subunit complement(3482968..3484077) Escherichia coli BW2952 7954129 YP_002928346.1 CDS yhhK NC_012759.1 3484501 3484884 D MG1655 equivalent: b3459; hypothetical protein 3484501..3484884 Escherichia coli BW2952 7954125 YP_002928347.1 CDS livJ NC_012759.1 3485072 3486175 R MG1655 equivalent: b3460; leucine/isoleucine/valine transporter subunit complement(3485072..3486175) Escherichia coli BW2952 7953032 YP_002928348.1 CDS rpoH NC_012759.1 3486446 3487300 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(3486446..3487300) Escherichia coli BW2952 7954130 YP_002928349.1 CDS ftsX NC_012759.1 3487545 3488603 R putative ABC transporter, membrane protein; cell division protein FtsX complement(3487545..3488603) Escherichia coli BW2952 7955989 YP_002928350.1 CDS ftsE NC_012759.1 3488596 3489264 R putative ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE complement(3488596..3489264) Escherichia coli BW2952 7955731 YP_002928351.1 CDS ftsY NC_012759.1 3489267 3490760 R signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY complement(3489267..3490760) Escherichia coli BW2952 7955719 YP_002928352.1 CDS rsmD NC_012759.1 3490910 3491506 D catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 3490910..3491506 Escherichia coli BW2952 7953742 YP_002928353.1 CDS yhhL NC_012759.1 3491496 3491765 D MG1655 equivalent: b3466; hypothetical protein 3491496..3491765 Escherichia coli BW2952 7955161 YP_002928354.1 CDS yhhM NC_012759.1 3491768 3492127 R MG1655 equivalent: b3467; hypothetical protein complement(3491768..3492127) Escherichia coli BW2952 7952725 YP_002928355.1 CDS yhhN NC_012759.1 3492268 3492894 D MG1655 equivalent: b3468; hypothetical protein 3492268..3492894 Escherichia coli BW2952 7952883 YP_002928356.1 CDS zntA NC_012759.1 3492968 3495166 D P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 3492968..3495166 Escherichia coli BW2952 7952726 YP_002928357.1 CDS sirA NC_012759.1 3495268 3495513 R TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA complement(3495268..3495513) Escherichia coli BW2952 7956289 YP_002928358.1 CDS yhhQ NC_012759.1 3495734 3496399 D MG1655 equivalent: b3471; hypothetical protein 3495734..3496399 Escherichia coli BW2952 7953076 YP_002928359.1 CDS dcrB NC_012759.1 3496472 3497029 D MG1655 equivalent: b3472; hypothetical protein 3496472..3497029 Escherichia coli BW2952 7952727 YP_002928360.1 CDS yhhS NC_012759.1 3497033 3498250 R MG1655 equivalent: b3473; major facilitator superfamily transporter complement(3497033..3498250) Escherichia coli BW2952 7954496 YP_002928361.1 CDS yhhT NC_012759.1 3498382 3499431 D MG1655 equivalent: b3474; putative inner membrane protein 3498382..3499431 Escherichia coli BW2952 7955666 YP_002928362.1 CDS acpT NC_012759.1 3499486 3500073 D MG1655 equivalent: b3475; holo-(acyl carrier protein) synthase 2 3499486..3500073 Escherichia coli BW2952 7955067 YP_002928363.1 CDS nikA NC_012759.1 3500184 3501758 D MG1655 equivalent: b3476; nickel transporter subunit 3500184..3501758 Escherichia coli BW2952 7953916 YP_002928364.1 CDS nikB NC_012759.1 3501758 3502702 D with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 3501758..3502702 Escherichia coli BW2952 7954377 YP_002928365.1 CDS nikC NC_012759.1 3502699 3503532 D with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 3502699..3503532 Escherichia coli BW2952 7954378 YP_002928366.1 CDS nikD NC_012759.1 3503532 3504296 D with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 3503532..3504296 Escherichia coli BW2952 7954379 YP_002928367.1 CDS nikE NC_012759.1 3504293 3505099 D with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 3504293..3505099 Escherichia coli BW2952 7954380 YP_002928368.1 CDS nikR NC_012759.1 3505105 3505506 D Inhibits transcription at high concentrations of nickel; nickel responsive regulator 3505105..3505506 Escherichia coli BW2952 7954381 YP_002928369.1 CDS rhsB NC_012759.1 3505709 3509944 D MG1655 equivalent: b3482; rhsB element core protein RshB 3505709..3509944 Escherichia coli BW2952 7953479 YP_002928370.1 CDS yhhH NC_012759.1 3509916 3510299 D MG1655 equivalent: b3483; hypothetical protein 3509916..3510299 Escherichia coli BW2952 7955950 YP_002928371.1 CDS yhhI NC_012759.1 3510895 3512031 D MG1655 equivalent: b3484; putative transposase 3510895..3512031 Escherichia coli BW2952 7955517 YP_002928372.1 CDS yhhJ NC_012759.1 3512196 3513323 R MG1655 equivalent: b3485; putative transporter subunit: membrane component of ABC superfamily complement(3512196..3513323) Escherichia coli BW2952 7955742 YP_002928373.1 CDS rbbA NC_012759.1 3513320 3516055 R MG1655 equivalent: b3486; fused ribosome-associated ATPase: ATP-binding protein/ATP-binding protein/putative membrane protein complement(3513320..3516055) Escherichia coli BW2952 7955732 YP_002928374.1 CDS yhiI NC_012759.1 3516052 3517119 R MG1655 equivalent: b3487; putative HlyD family secretion protein complement(3516052..3517119) Escherichia coli BW2952 7953740 YP_002928375.1 CDS yhiJ NC_012759.1 3517485 3519107 R MG1655 equivalent: b3488; hypothetical protein complement(3517485..3519107) Escherichia coli BW2952 7954945 YP_002928376.1 CDS yhiM NC_012759.1 3521316 3522410 D MG1655 equivalent: b3491; hypothetical protein 3521316..3522410 Escherichia coli BW2952 7955422 YP_002928377.1 CDS yhiN NC_012759.1 3522725 3523927 R MG1655 equivalent: b3492; putative oxidoreductase with FAD/NAD(P)-binding domain complement(3522725..3523927) Escherichia coli BW2952 7952728 YP_002928378.1 CDS pitA NC_012759.1 3524159 3525658 D MG1655 equivalent: b3493; phosphate transporter, low-affinity 3524159..3525658 Escherichia coli BW2952 7955240 YP_002928379.1 CDS uspB NC_012759.1 3525902 3526237 R ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB complement(3525902..3526237) Escherichia coli BW2952 7954519 YP_002928380.1 CDS uspA NC_012759.1 3526628 3527062 D MG1655 equivalent: b3495; universal stress global response regulator 3526628..3527062 Escherichia coli BW2952 7955746 YP_002928381.1 CDS yhiP NC_012759.1 3527379 3528848 D member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 3527379..3528848 Escherichia coli BW2952 7956253 YP_002928382.1 CDS yhiQ NC_012759.1 3528897 3529649 R predicted SAM-dependent methyltransferase; putative methyltransferase complement(3528897..3529649) Escherichia coli BW2952 7955705 YP_002928383.1 CDS prlC NC_012759.1 3529657 3531699 R MG1655 equivalent: b3498; oligopeptidase A complement(3529657..3531699) Escherichia coli BW2952 7955582 YP_002928384.1 CDS yhiR NC_012759.1 3531902 3532744 D MG1655 equivalent: b3499; putative DNA processing protein 3531902..3532744 Escherichia coli BW2952 7954421 YP_002928385.1 CDS gor NC_012759.1 3532816 3534168 D catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 3532816..3534168 Escherichia coli BW2952 7954736 YP_002928386.1 CDS dinQ NC_012759.1 3534222 3534350 R MG1655 equivalent: b4613; Damage inducible protein complement(3534222..3534350) Escherichia coli BW2952 7953839 YP_002928387.1 CDS arsR NC_012759.1 3535045 3535398 D regulates the expression of of the arsRBC involved in resistance to arsenic; DNA-binding transcriptional repressor ArsR 3535045..3535398 Escherichia coli BW2952 7953225 YP_002928388.1 CDS arsB NC_012759.1 3535452 3536741 D MG1655 equivalent: b3502; arsenite/antimonite transporter 3535452..3536741 Escherichia coli BW2952 7953468 YP_002928389.1 CDS arsC NC_012759.1 3536754 3537179 D MG1655 equivalent: b3503; arsenate reductase 3536754..3537179 Escherichia coli BW2952 7952506 YP_002928390.1 CDS insH NC_012759.1 3538699 3539715 R MG1655 equivalent: b3505; IS5 transposase and trans-activator complement(3538699..3539715) Escherichia coli BW2952 7952505 YP_002928391.1 CDS slp NC_012759.1 3540478 3541044 D MG1655 equivalent: b3506; outer membrane lipoprotein 3540478..3541044 Escherichia coli BW2952 7954044 YP_002928392.1 CDS dctR NC_012759.1 3541200 3541730 D MG1655 equivalent: b3507; putative DNA-binding ranscriptional regulator 3541200..3541730 Escherichia coli BW2952 7954439 YP_002928393.1 CDS yhiD NC_012759.1 3541772 3542419 R inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; putative Mg(2+) transport ATPase complement(3541772..3542419) Escherichia coli BW2952 7954739 YP_002928394.1 CDS hdeB NC_012759.1 3542483 3542809 R MG1655 equivalent: b3509; acid-resistance protein complement(3542483..3542809) Escherichia coli BW2952 7955163 YP_002928395.1 CDS hdeA NC_012759.1 3542925 3543257 R inactive form; acid-resistance protein complement(3542925..3543257) Escherichia coli BW2952 7952410 YP_002928396.1 CDS hdeD NC_012759.1 3543512 3544084 D MG1655 equivalent: b3511; acid-resistance membrane protein 3543512..3544084 Escherichia coli BW2952 7956071 YP_002928397.1 CDS gadE NC_012759.1 3544883 3545410 D MG1655 equivalent: b3512; DNA-binding transcriptional activator 3544883..3545410 Escherichia coli BW2952 7952409 YP_002928398.1 CDS mdtE NC_012759.1 3545749 3546906 D with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 3545749..3546906 Escherichia coli BW2952 7953383 YP_002928399.1 CDS mdtF NC_012759.1 3546931 3550044 D MG1655 equivalent: b3514; multidrug transporter, RpoS-dependent 3546931..3550044 Escherichia coli BW2952 7954314 YP_002928400.1 CDS gadW NC_012759.1 3550407 3551135 R MG1655 equivalent: b3515; DNA-binding transcriptional activator complement(3550407..3551135) Escherichia coli BW2952 7954315 YP_002928401.1 CDS gadX NC_012759.1 3551503 3552327 R regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX complement(3551503..3552327) Escherichia coli BW2952 7952196 YP_002928402.1 CDS gadA NC_012759.1 3552697 3554097 R MG1655 equivalent: b3517; glutamate decarboxylase complement(3552697..3554097) Escherichia coli BW2952 7953411 YP_002928403.1 CDS yhjA NC_012759.1 3554308 3555705 R MG1655 equivalent: b3518; putative cytochrome C peroxidase complement(3554308..3555705) Escherichia coli BW2952 7953818 YP_002928404.1 CDS treF NC_012759.1 3556109 3557758 D cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 3556109..3557758 Escherichia coli BW2952 7954709 YP_002928405.1 CDS yhjB NC_012759.1 3557809 3558411 R MG1655 equivalent: b3520; putative DNA-binding response regulator in two-component regulatory system complement(3557809..3558411) Escherichia coli BW2952 7953205 YP_002928406.1 CDS yhjC NC_012759.1 3558931 3559830 D MG1655 equivalent: b3521; putative DNA-binding transcriptional regulator 3558931..3559830 Escherichia coli BW2952 7954740 YP_002928407.1 CDS yhjD NC_012759.1 3559879 3560892 D MG1655 equivalent: b3522; hypothetical protein 3559879..3560892 Escherichia coli BW2952 7954811 YP_002928408.1 CDS yhjE NC_012759.1 3561303 3562625 D MG1655 equivalent: b3523; putative transporter 3561303..3562625 Escherichia coli BW2952 7952729 YP_002928409.1 CDS yhjG NC_012759.1 3562807 3564882 R MG1655 equivalent: b3524; putative outer membrane biogenesis protein complement(3562807..3564882) Escherichia coli BW2952 7955706 YP_002928410.1 CDS yhjH NC_012759.1 3564937 3565704 R in Escherichia coli this protein is involved in flagellar function; EAL domain-containing protein complement(3564937..3565704) Escherichia coli BW2952 7955195 YP_002928411.1 CDS kdgK NC_012759.1 3565936 3566865 D MG1655 equivalent: b3526; ketodeoxygluconokinase 3565936..3566865 Escherichia coli BW2952 7953512 YP_002928412.1 CDS yhjJ NC_012759.1 3566961 3568457 R MG1655 equivalent: b3527; putative zinc-dependent peptidase complement(3566961..3568457) Escherichia coli BW2952 7954059 YP_002928413.1 CDS dctA NC_012759.1 3568678 3569964 R involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA complement(3568678..3569964) Escherichia coli BW2952 7955755 YP_002928414.1 CDS yhjK NC_012759.1 3570147 3572102 R HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a putative phosphodiesterase protein from E. coli; putative phosphodiesterase complement(3570147..3572102) Escherichia coli BW2952 7952588 YP_002928415.1 CDS bcsC NC_012759.1 3572217 3575639 R cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC complement(3572217..3575639) Escherichia coli BW2952 7954725 YP_002928416.1 CDS bcsZ NC_012759.1 3575672 3576778 R catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase complement(3575672..3576778) Escherichia coli BW2952 7952623 YP_002928417.1 CDS bcsB NC_012759.1 3576785 3579124 R binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein complement(3576785..3579124) Escherichia coli BW2952 7953516 YP_002928418.1 CDS bcsA NC_012759.1 3579135 3581753 R polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit complement(3579135..3581753) Escherichia coli BW2952 7955919 YP_002928419.1 CDS yhjR NC_012759.1 3582514 3582702 R MG1655 equivalent: b3535; hypothetical protein complement(3582514..3582702) Escherichia coli BW2952 7952624 YP_002928420.1 CDS bcsE NC_012759.1 3582975 3584546 D MG1655 equivalent: b3536; hypothetical protein 3582975..3584546 Escherichia coli BW2952 7952884 YP_002928421.1 CDS bcsF NC_012759.1 3584543 3584734 D MG1655 equivalent: b3537; hypothetical protein 3584543..3584734 Escherichia coli BW2952 7953033 YP_002928422.1 CDS bcsG NC_012759.1 3584731 3586410 D MG1655 equivalent: b3538; putative inner membrane protein 3584731..3586410 Escherichia coli BW2952 7955518 YP_002928423.1 CDS ldrD NC_012759.1 3586497 3586604 R MG1655 equivalent: b4453; toxic polypeptide, small complement(3586497..3586604) Escherichia coli BW2952 7955068 YP_002928424.1 CDS yhjV NC_012759.1 3587080 3588351 D MG1655 equivalent: b3539; putative transporter 3587080..3588351 Escherichia coli BW2952 7952197 YP_002928425.1 CDS dppF NC_012759.1 3588381 3589385 R Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit complement(3588381..3589385) Escherichia coli BW2952 7955707 YP_002928426.1 CDS dppD NC_012759.1 3589382 3590365 R DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit complement(3589382..3590365) Escherichia coli BW2952 7953264 YP_002928427.1 CDS dppC NC_012759.1 3590376 3591278 R MG1655 equivalent: b3542; dipeptide transporter complement(3590376..3591278) Escherichia coli BW2952 7953265 YP_002928428.1 CDS dppB NC_012759.1 3591288 3592307 R transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB complement(3591288..3592307) Escherichia coli BW2952 7953266 YP_002928429.1 CDS dppA NC_012759.1 3592615 3594222 R MG1655 equivalent: b3544; dipeptide transporter complement(3592615..3594222) Escherichia coli BW2952 7953267 YP_002928430.1 CDS eptB NC_012759.1 3595133 3596824 R catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase complement(3595133..3596824) Escherichia coli BW2952 7952073 YP_002928431.1 CDS yhjX NC_012759.1 3597148 3598356 R MG1655 equivalent: b3547; putative transporter complement(3597148..3598356) Escherichia coli BW2952 7955143 YP_002928432.1 CDS yhjY NC_012759.1 3598585 3599283 R MG1655 equivalent: b3548; hypothetical protein complement(3598585..3599283) Escherichia coli BW2952 7955667 YP_002928433.1 CDS tag NC_012759.1 3599441 3600004 D constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyladenine DNA glycosylase 3599441..3600004 Escherichia coli BW2952 7952885 YP_002928434.1 CDS yiaC NC_012759.1 3600001 3600441 D MG1655 equivalent: b3550; hypothetical protein 3600001..3600441 Escherichia coli BW2952 7952313 YP_002928435.1 CDS bisC NC_012759.1 3600410 3602743 R MG1655 equivalent: b3551; biotin sulfoxide reductase complement(3600410..3602743) Escherichia coli BW2952 7954621 YP_002928436.1 CDS yiaD NC_012759.1 3602896 3603555 D MG1655 equivalent: b3552; putative outer membrane lipoprotein 3602896..3603555 Escherichia coli BW2952 7952581 YP_002928437.1 CDS ghrB NC_012759.1 3603659 3604633 D MG1655 equivalent: b3553; 2-keto-D-gluconate reductase (glyoxalate reductase) (2-ketoaldonate reductase) 3603659..3604633 Escherichia coli BW2952 7955205 YP_002928438.1 CDS yiaF NC_012759.1 3604683 3605393 R MG1655 equivalent: b3554; hypothetical protein complement(3604683..3605393) Escherichia coli BW2952 7952263 YP_002928439.1 CDS yiaG NC_012759.1 3605827 3606117 D MG1655 equivalent: b3555; putative transcriptional regulator 3605827..3606117 Escherichia coli BW2952 7952886 YP_002928440.1 CDS cspA NC_012759.1 3606398 3606610 D MG1655 equivalent: b3556; major cold shock protein 3606398..3606610 Escherichia coli BW2952 7955638 YP_002928441.1 CDS hokA NC_012759.1 3606797 3606949 R MG1655 equivalent: b4455; small toxic polypeptide complement(3606797..3606949) Escherichia coli BW2952 7954193 YP_002928442.1 CDS insJ NC_012759.1 3607029 3607550 D MG1655 equivalent: b3557; IS150 protein InsA 3607029..3607550 Escherichia coli BW2952 7956158 YP_002928443.1 CDS insK NC_012759.1 3607547 3608398 D MG1655 equivalent: b3558; transposase IS150 3607547..3608398 Escherichia coli BW2952 7954024 YP_002928444.1 CDS glyS NC_012759.1 3608677 3610746 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(3608677..3610746) Escherichia coli BW2952 7952205 YP_002928445.1 CDS glyQ NC_012759.1 3610756 3611667 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(3610756..3611667) Escherichia coli BW2952 7953862 YP_002928446.1 CDS ysaB NC_012759.1 3611762 3612061 R MG1655 equivalent: b4553; hypothetical protein complement(3611762..3612061) Escherichia coli BW2952 7953861 YP_002928447.1 CDS wecH NC_012759.1 3612236 3613231 D MG1655 equivalent: b3561; hypothetical protein 3612236..3613231 Escherichia coli BW2952 7955436 YP_002928448.1 CDS yiaA NC_012759.1 3613273 3613710 R MG1655 equivalent: b3562; hypothetical protein complement(3613273..3613710) Escherichia coli BW2952 7952730 YP_002928449.1 CDS yiaB NC_012759.1 3613756 3614097 R MG1655 equivalent: b3563; hypothetical protein complement(3613756..3614097) Escherichia coli BW2952 7952687 YP_002928450.1 CDS xylB NC_012759.1 3614266 3615720 R MG1655 equivalent: b3564; xylulokinase complement(3614266..3615720) Escherichia coli BW2952 7952688 YP_002928451.1 CDS xylA NC_012759.1 3615792 3617114 R catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase complement(3615792..3617114) Escherichia coli BW2952 7956281 YP_002928452.1 CDS xylF NC_012759.1 3617480 3618472 D periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 3617480..3618472 Escherichia coli BW2952 7953507 YP_002928453.1 CDS xylG NC_012759.1 3618550 3620091 D with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 3618550..3620091 Escherichia coli BW2952 7953509 YP_002928454.1 CDS xylH NC_012759.1 3620069 3621250 D MG1655 equivalent: b3568; D-xylose transporter subunit 3620069..3621250 Escherichia coli BW2952 7953678 YP_002928455.1 CDS xylR NC_012759.1 3621328 3622506 D MG1655 equivalent: b3569; DNA-binding transcriptional activator, xylose-binding 3621328..3622506 Escherichia coli BW2952 7953510 YP_002928456.1 CDS bax NC_012759.1 3622702 3623526 R MG1655 equivalent: b3570; hypothetical protein complement(3622702..3623526) Escherichia coli BW2952 7953401 YP_002928457.1 CDS malS NC_012759.1 3623846 3625876 D periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 3623846..3625876 Escherichia coli BW2952 7952887 YP_002928458.1 CDS avtA NC_012759.1 3626054 3627307 D transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 3626054..3627307 Escherichia coli BW2952 7952455 YP_002928459.1 CDS ysaA NC_012759.1 3627458 3627931 R MG1655 equivalent: b3573; putative hydrogenase, 4Fe-4S ferredoxin-type component complement(3627458..3627931) Escherichia coli BW2952 7956269 YP_002928460.1 CDS yiaJ NC_012759.1 3628033 3628881 R MG1655 equivalent: b3574; putative DNA-binding transcriptional repressor complement(3628033..3628881) Escherichia coli BW2952 7954949 YP_002928461.1 CDS yiaK NC_012759.1 3629082 3630080 D NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 3629082..3630080 Escherichia coli BW2952 7954824 YP_002928462.1 CDS yiaL NC_012759.1 3630092 3630559 D MG1655 equivalent: b3576; hypothetical protein 3630092..3630559 Escherichia coli BW2952 7952236 YP_002928463.1 CDS yiaM NC_012759.1 3630677 3631150 D membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO; 2,3-diketo-L-gulonate TRAP transporter small permease 3630677..3631150 Escherichia coli BW2952 7953034 YP_002928464.1 CDS yiaN NC_012759.1 3631153 3632430 D MG1655 equivalent: b3578; putative transporter 3631153..3632430 Escherichia coli BW2952 7955708 YP_002928465.1 CDS yiaO NC_012759.1 3632443 3633429 D MG1655 equivalent: b3579; putative transporter 3632443..3633429 Escherichia coli BW2952 7955709 YP_002928466.1 CDS lyx NC_012759.1 3633433 3634929 D MG1655 equivalent: b3580; L-xylulose kinase 3633433..3634929 Escherichia coli BW2952 7955710 YP_002928467.1 CDS sgbH NC_012759.1 3634926 3635588 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate; 3-keto-L-gulonate-6-phosphate decarboxylase 3634926..3635588 Escherichia coli BW2952 7954178 YP_002928468.1 CDS sgbU NC_012759.1 3635581 3636441 D L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; putative L-xylulose 5-phosphate 3-epimerase 3635581..3636441 Escherichia coli BW2952 7952309 YP_002928469.1 CDS sgbE NC_012759.1 3636435 3637130 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 3636435..3637130 Escherichia coli BW2952 7955125 YP_002928470.1 CDS yiaT NC_012759.1 3637477 3638217 R MG1655 equivalent: b3584; hypothetical protein complement(3637477..3638217) Escherichia coli BW2952 7954169 YP_002928471.1 CDS yiaU NC_012759.1 3638341 3639315 D MG1655 equivalent: b3585; putative DNA-binding transcriptional regulator 3638341..3639315 Escherichia coli BW2952 7955423 YP_002928472.1 CDS yiaV NC_012759.1 3639312 3640448 R MG1655 equivalent: b3586; membrane fusion protein (MFP) component of efflux pump, signal anchor complement(3639312..3640448) Escherichia coli BW2952 7954812 YP_002928473.1 CDS yiaW NC_012759.1 3640454 3640777 R MG1655 equivalent: b3587; hypothetical protein complement(3640454..3640777) Escherichia coli BW2952 7954227 YP_002928474.1 CDS aldB NC_012759.1 3641322 3642860 R MG1655 equivalent: b3588; aldehyde dehydrogenase B complement(3641322..3642860) Escherichia coli BW2952 7952689 YP_002928475.1 CDS yiaY NC_012759.1 3643025 3644176 R MG1655 equivalent: b3589; putative alcohol dehydrogenase complement(3643025..3644176) Escherichia coli BW2952 7952444 YP_002928476.1 CDS selB NC_012759.1 3644366 3646210 R MG1655 equivalent: b3590; selenocysteinyl-tRNA-specific translation factor complement(3644366..3646210) Escherichia coli BW2952 7954869 YP_002928477.1 CDS selA NC_012759.1 3646207 3647598 R catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase complement(3646207..3647598) Escherichia coli BW2952 7956008 YP_002928478.1 CDS yibF NC_012759.1 3647696 3648304 R MG1655 equivalent: b3592; putative glutathione S-transferase complement(3647696..3648304) Escherichia coli BW2952 7956007 YP_002928479.1 CDS rhsA NC_012759.1 3648532 3652665 D MG1655 equivalent: b3593; rhsA element core protein RshA 3648532..3652665 Escherichia coli BW2952 7954927 YP_002928480.1 CDS yibA NC_012759.1 3652686 3653528 D MG1655 equivalent: b3594; hypothetical protein 3652686..3653528 Escherichia coli BW2952 7955949 YP_002928481.1 CDS yibG NC_012759.1 3654526 3654987 D MG1655 equivalent: b3596; hypothetical protein 3654526..3654987 Escherichia coli BW2952 7954179 YP_002928482.1 CDS yibV NC_012759.1 3655694 3656029 D MG1655 equivalent: b4615; hypothetical protein 3655694..3656029 Escherichia coli BW2952 7953035 YP_002928483.1 CDS yibH NC_012759.1 3656592 3657728 R MG1655 equivalent: b3597; hypothetical protein complement(3656592..3657728) Escherichia coli BW2952 7953986 YP_002928484.1 CDS yibI NC_012759.1 3657731 3658093 R MG1655 equivalent: b3598; putative inner membrane protein complement(3657731..3658093) Escherichia coli BW2952 7955424 YP_002928485.1 CDS mtlA NC_012759.1 3658630 3660543 D MG1655 equivalent: b3599; fused mannitol-specific PTS enzymes: IIA components/IIB components/IIC components 3658630..3660543 Escherichia coli BW2952 7955012 YP_002928486.1 CDS mtlD NC_012759.1 3660773 3661921 D MG1655 equivalent: b3600; mannitol-1-phosphate 5-dehydrogenase 3660773..3661921 Escherichia coli BW2952 7953698 YP_002928487.1 CDS mtlR NC_012759.1 3661921 3662508 D Acts as a repressor of the mtlAD operon; mannitol repressor protein 3661921..3662508 Escherichia coli BW2952 7954211 YP_002928488.1 CDS yibT NC_012759.1 3662520 3662729 R MG1655 equivalent: b4554; hypothetical protein complement(3662520..3662729) Escherichia coli BW2952 7953342 YP_002928489.1 CDS yibL NC_012759.1 3663014 3663376 D MG1655 equivalent: b3602; hypothetical protein 3663014..3663376 Escherichia coli BW2952 7955437 YP_002928490.1 CDS lldP NC_012759.1 3663748 3665403 D MG1655 equivalent: b3603; L-lactate permease 3663748..3665403 Escherichia coli BW2952 7953036 YP_002928491.1 CDS lldR NC_012759.1 3665403 3666179 D represses the lctPRD operon; DNA-binding transcriptional repressor LldR 3665403..3666179 Escherichia coli BW2952 7954162 YP_002928492.1 CDS lldD NC_012759.1 3666176 3667366 D flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 3666176..3667366 Escherichia coli BW2952 7953469 YP_002928493.1 CDS yibK NC_012759.1 3667564 3668037 D member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; putative tRNA/rRNA methyltransferase YibK 3667564..3668037 Escherichia coli BW2952 7954161 YP_002928494.1 CDS cysE NC_012759.1 3668090 3668911 R catalyzes the O-acetylation of serine; serine acetyltransferase complement(3668090..3668911) Escherichia coli BW2952 7955574 YP_002928495.1 CDS gpsA NC_012759.1 3668991 3670010 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(3668991..3670010) Escherichia coli BW2952 7956028 YP_002928496.1 CDS secB NC_012759.1 3670010 3670477 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB complement(3670010..3670477) Escherichia coli BW2952 7953848 YP_002928497.1 CDS grxC NC_012759.1 3670540 3670791 R MG1655 equivalent: b3610; glutaredoxin 3 complement(3670540..3670791) Escherichia coli BW2952 7955792 YP_002928498.1 CDS yibN NC_012759.1 3670933 3671364 R MG1655 equivalent: b3611; putative rhodanese-related sulfurtransferase complement(3670933..3671364) Escherichia coli BW2952 7953837 YP_002928499.1 CDS gpmM NC_012759.1 3671609 3673153 D catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 3671609..3673153 Escherichia coli BW2952 7955569 YP_002928500.1 CDS envC NC_012759.1 3673187 3674446 D MG1655 equivalent: b3613; hypothetical protein 3673187..3674446 Escherichia coli BW2952 7954534 YP_002928501.1 CDS yibQ NC_012759.1 3674450 3675409 D MG1655 equivalent: b3614; putative polysaccharide deacetylase 3674450..3675409 Escherichia coli BW2952 7955779 YP_002928502.1 CDS yibD NC_012759.1 3675396 3676430 R MG1655 equivalent: b3615; putative glycosyl transferase complement(3675396..3676430) Escherichia coli BW2952 7955325 YP_002928503.1 CDS tdh NC_012759.1 3676669 3677694 R converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase complement(3676669..3677694) Escherichia coli BW2952 7954938 YP_002928504.1 CDS kbl NC_012759.1 3677704 3678900 R catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase complement(3677704..3678900) Escherichia coli BW2952 7956142 YP_002928505.1 CDS htrL NC_012759.1 3679175 3680032 R MG1655 equivalent: b3618; hypothetical protein complement(3679175..3680032) Escherichia coli BW2952 7953858 YP_002928506.1 CDS rfaD NC_012759.1 3680336 3681268 D catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 3680336..3681268 Escherichia coli BW2952 7955425 YP_002928507.1 CDS rfaF NC_012759.1 3681278 3682324 D catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose--LPS heptosyltransferase 3681278..3682324 Escherichia coli BW2952 7952431 YP_002928508.1 CDS rfaC NC_012759.1 3682328 3683287 D MG1655 equivalent: b3621; ADP-heptose--LPS heptosyltransferase 3682328..3683287 Escherichia coli BW2952 7952430 YP_002928509.1 CDS rfaL NC_012759.1 3683297 3684556 D MG1655 equivalent: b3622; O-antigen ligase 3683297..3684556 Escherichia coli BW2952 7952429 YP_002928510.1 CDS waaU NC_012759.1 3684588 3685661 R MG1655 equivalent: b3623; lipopolysaccharide core biosynthesis complement(3684588..3685661) Escherichia coli BW2952 7954417 YP_002928511.1 CDS rfaZ NC_012759.1 3685694 3686545 R MG1655 equivalent: b3624; lipopolysaccharide core biosynthesis protein complement(3685694..3686545) Escherichia coli BW2952 7954150 YP_002928512.1 CDS rfaY NC_012759.1 3686616 3687314 R MG1655 equivalent: b3625; lipopolysaccharide core biosynthesis protein complement(3686616..3687314) Escherichia coli BW2952 7954151 YP_002928513.1 CDS rfaJ NC_012759.1 3687332 3688348 R MG1655 equivalent: b3626; UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase complement(3687332..3688348) Escherichia coli BW2952 7954152 YP_002928514.1 CDS rfaI NC_012759.1 3688388 3689407 R MG1655 equivalent: b3627; UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase complement(3688388..3689407) Escherichia coli BW2952 7956230 YP_002928515.1 CDS rfaB NC_012759.1 3689407 3690516 R MG1655 equivalent: b3628; UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase complement(3689407..3690516) Escherichia coli BW2952 7956229 YP_002928516.1 CDS rfaS NC_012759.1 3690530 3691465 R MG1655 equivalent: b3629; lipopolysaccharide core biosynthesis protein complement(3690530..3691465) Escherichia coli BW2952 7956228 YP_002928517.1 CDS rfaP NC_012759.1 3691502 3692299 R MG1655 equivalent: b3630; kinase that phosphorylates core heptose of lipopolysaccharide complement(3691502..3692299) Escherichia coli BW2952 7954153 YP_002928518.1 CDS rfaG NC_012759.1 3692292 3693416 R MG1655 equivalent: b3631; glucosyltransferase I complement(3692292..3693416) Escherichia coli BW2952 7954061 YP_002928519.1 CDS rfaQ NC_012759.1 3693413 3694447 R MG1655 equivalent: b3632; lipopolysaccharide core biosynthesis protein complement(3693413..3694447) Escherichia coli BW2952 7953813 YP_002928520.1 CDS waaA NC_012759.1 3694889 3696166 D catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 3694889..3696166 Escherichia coli BW2952 7954154 YP_002928521.1 CDS coaD NC_012759.1 3696174 3696653 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 3696174..3696653 Escherichia coli BW2952 7952302 YP_002928522.1 CDS mutM NC_012759.1 3696692 3697501 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(3696692..3697501) Escherichia coli BW2952 7954463 YP_002928523.1 CDS rpmG NC_012759.1 3697599 3697766 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(3697599..3697766) Escherichia coli BW2952 7953614 YP_002928524.1 CDS rpmB NC_012759.1 3697787 3698023 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(3697787..3698023) Escherichia coli BW2952 7952361 YP_002928525.1 CDS radC NC_012759.1 3698240 3698908 R Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC complement(3698240..3698908) Escherichia coli BW2952 7952355 YP_002928526.1 CDS dfp NC_012759.1 3699080 3700300 D catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 3699080..3700300 Escherichia coli BW2952 7955783 YP_002928527.1 CDS dut NC_012759.1 3700281 3700736 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 3700281..3700736 Escherichia coli BW2952 7953651 YP_002928528.1 CDS slmA NC_012759.1 3700843 3701439 D FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 3700843..3701439 Escherichia coli BW2952 7953237 YP_002928529.1 CDS pyrE NC_012759.1 3701476 3702117 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(3701476..3702117) Escherichia coli BW2952 7953271 YP_002928530.1 CDS rph NC_012759.1 3702183 3702899 R RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH complement(3702183..3702899) Escherichia coli BW2952 7954431 YP_002928531.1 CDS yicC NC_012759.1 3703026 3703889 D MG1655 equivalent: b3644; hypothetical protein 3703026..3703889 Escherichia coli BW2952 7953231 YP_002928532.1 CDS dinD NC_012759.1 3704110 3704934 D MG1655 equivalent: b3645; DNA-damage-inducible protein D 3704110..3704934 Escherichia coli BW2952 7953037 YP_002928533.1 CDS yicG NC_012759.1 3705224 3705841 D MG1655 equivalent: b3646; hypothetical protein 3705224..3705841 Escherichia coli BW2952 7953485 YP_002928534.1 CDS ligB NC_012759.1 3705838 3707520 R this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB complement(3705838..3707520) Escherichia coli BW2952 7952731 YP_002928535.1 CDS gmk NC_012759.1 3707778 3708401 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 3707778..3708401 Escherichia coli BW2952 7953312 YP_002928536.1 CDS rpoZ NC_012759.1 3708456 3708731 D promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 3708456..3708731 Escherichia coli BW2952 7953887 YP_002928537.1 CDS spoT NC_012759.1 3708750 3710864 D MG1655 equivalent: b3650; bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 3708750..3710864 Escherichia coli BW2952 7955986 YP_002928538.1 CDS trmH NC_012759.1 3710871 3711560 D specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 3710871..3711560 Escherichia coli BW2952 7952555 YP_002928539.1 CDS recG NC_012759.1 3711566 3713647 D catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 3711566..3713647 Escherichia coli BW2952 7956197 YP_002928540.1 CDS gltS NC_012759.1 3713816 3715021 R MG1655 equivalent: b3653; glutamate transporter complement(3713816..3715021) Escherichia coli BW2952 7952530 YP_002928541.1 CDS yicE NC_012759.1 3715301 3716692 D MG1655 equivalent: b3654; putative transporter 3715301..3716692 Escherichia coli BW2952 7953824 YP_002928542.1 CDS yicH NC_012759.1 3716813 3718522 D MG1655 equivalent: b3655; hypothetical protein 3716813..3718522 Escherichia coli BW2952 7955711 YP_002928543.1 CDS yicI NC_012759.1 3718575 3720893 R catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase complement(3718575..3720893) Escherichia coli BW2952 7953038 YP_002928544.1 CDS yicJ NC_012759.1 3720903 3722285 R may be involved in the transport of galactosides-pentoses-hexuronides; putative transporter complement(3720903..3722285) Escherichia coli BW2952 7954634 YP_002928545.1 CDS setC NC_012759.1 3723309 3724493 D MG1655 equivalent: b3659; putative sugar efflux system 3723309..3724493 Escherichia coli BW2952 7952147 YP_002928546.1 CDS yicL NC_012759.1 3724604 3725527 D MG1655 equivalent: b3660; putative inner membrane protein 3724604..3725527 Escherichia coli BW2952 7955603 YP_002928547.1 CDS nlpA NC_012759.1 3725531 3726349 R MG1655 equivalent: b3661; hypothetical protein complement(3725531..3726349) Escherichia coli BW2952 7955069 YP_002928548.1 CDS yicS NC_012759.1 3726571 3726864 D MG1655 equivalent: b4555; hypothetical protein 3726571..3726864 Escherichia coli BW2952 7953204 YP_002928549.1 CDS nepI NC_012759.1 3726905 3728095 R experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS; ribonucleoside transporter complement(3726905..3728095) Escherichia coli BW2952 7955537 YP_002928550.1 CDS yicN NC_012759.1 3728306 3728758 R MG1655 equivalent: b3663; hypothetical protein complement(3728306..3728758) Escherichia coli BW2952 7955669 YP_002928551.1 CDS yicO NC_012759.1 3728811 3730145 R MG1655 equivalent: b3664; putative xanthine/uracil permase complement(3728811..3730145) Escherichia coli BW2952 7952888 YP_002928552.1 CDS ade NC_012759.1 3730320 3732086 D catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 3730320..3732086 Escherichia coli BW2952 7955752 YP_002928553.1 CDS uhpT NC_012759.1 3732132 3733523 R cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter complement(3732132..3733523) Escherichia coli BW2952 7953166 YP_002928554.1 CDS uhpC NC_012759.1 3733661 3734980 R membrane protein regulates uhpT expression; regulatory protein UhpC complement(3733661..3734980) Escherichia coli BW2952 7953905 YP_002928555.1 CDS uhpB NC_012759.1 3734990 3736492 R Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB complement(3734990..3736492) Escherichia coli BW2952 7954230 YP_002928556.1 CDS uhpA NC_012759.1 3736492 3737082 R response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA complement(3736492..3737082) Escherichia coli BW2952 7956027 YP_002928557.1 CDS ilvN NC_012759.1 3737158 3737448 R with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit complement(3737158..3737448) Escherichia coli BW2952 7953363 YP_002928558.1 CDS ilvB NC_012759.1 3737452 3739140 R MG1655 equivalent: b3671; acetolactate synthase catalytic subunit complement(3737452..3739140) Escherichia coli BW2952 7952391 YP_002928559.1 CDS ivbL NC_012759.1 3739246 3739344 R MG1655 equivalent: b3672; ilvB operon leader peptide complement(3739246..3739344) Escherichia coli BW2952 7952390 YP_002928560.1 CDS tisA NC_012759.1 3739799 3739912 D MG1655 equivalent: b4617; hypothetical protein 3739799..3739912 Escherichia coli BW2952 7952097 YP_002928561.1 CDS tisB NC_012759.1 3739909 3739998 D MG1655 equivalent: b4618; toxic peptide TisB 3739909..3739998 Escherichia coli BW2952 7954134 YP_002928562.1 CDS emrD NC_012759.1 3740278 3741462 D multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 3740278..3741462 Escherichia coli BW2952 7954135 YP_002928563.1 CDS yidF NC_012759.1 3741470 3741967 R MG1655 equivalent: b3674; putative DNA-binding transcriptional regulator complement(3741470..3741967) Escherichia coli BW2952 7954305 YP_002928564.1 CDS yidG NC_012759.1 3741964 3742326 R MG1655 equivalent: b3675; putative inner membrane protein complement(3741964..3742326) Escherichia coli BW2952 7954784 YP_002928565.1 CDS yidH NC_012759.1 3742316 3742663 R MG1655 equivalent: b3676; hypothetical protein complement(3742316..3742663) Escherichia coli BW2952 7955013 YP_002928566.1 CDS yidI NC_012759.1 3742771 3743220 D MG1655 equivalent: b3677; putative inner membrane protein 3742771..3743220 Escherichia coli BW2952 7952690 YP_002928567.1 CDS yidJ NC_012759.1 3743267 3744760 R MG1655 equivalent: b3678; putative sulfatase/phosphatase complement(3743267..3744760) Escherichia coli BW2952 7955070 YP_002928568.1 CDS yidK NC_012759.1 3744757 3746472 R uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; putative symporter YidK complement(3744757..3746472) Escherichia coli BW2952 7955615 YP_002928569.1 CDS yidL NC_012759.1 3746609 3747532 D MG1655 equivalent: b3680; putative DNA-binding transcriptional regulator 3746609..3747532 Escherichia coli BW2952 7955670 YP_002928570.1 CDS yidP NC_012759.1 3750255 3750971 D MG1655 equivalent: b3684; putative DNA-binding transcriptional regulator 3750255..3750971 Escherichia coli BW2952 7954813 YP_002928571.1 CDS yidE NC_012759.1 3750968 3752629 R MG1655 equivalent: b3685; hypothetical protein complement(3750968..3752629) Escherichia coli BW2952 7954814 YP_002928572.1 CDS ibpB NC_012759.1 3752825 3753253 R 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB complement(3752825..3753253) Escherichia coli BW2952 7955671 YP_002928573.1 CDS ibpA NC_012759.1 3753365 3753778 R with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA complement(3753365..3753778) Escherichia coli BW2952 7953890 YP_002928574.1 CDS yidQ NC_012759.1 3754084 3754416 D MG1655 equivalent: b3688; hypothetical protein 3754084..3754416 Escherichia coli BW2952 7953891 YP_002928575.1 CDS yidR NC_012759.1 3754418 3755632 R MG1655 equivalent: b3689; hypothetical protein complement(3754418..3755632) Escherichia coli BW2952 7952752 YP_002928576.1 CDS cbrA NC_012759.1 3755733 3756797 D FAD/NAD(P)-binding domain; putative oxidoreductase 3755733..3756797 Escherichia coli BW2952 7952889 YP_002928577.1 CDS dgoT NC_012759.1 3756794 3758086 R MG1655 equivalent: b3691; D-galactonate transporter complement(3756794..3758086) Escherichia coli BW2952 7955244 YP_002928578.1 CDS dgoD NC_012759.1 3758206 3759354 R MG1655 equivalent: b4478; galactonate dehydratase complement(3758206..3759354) Escherichia coli BW2952 7953242 YP_002928579.1 CDS dgoA NC_012759.1 3759351 3759968 R catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase complement(3759351..3759968) Escherichia coli BW2952 7953759 YP_002928580.1 CDS dgoK NC_012759.1 3759952 3760830 R MG1655 equivalent: b3693; 2-oxo-3-deoxygalactonate kinase complement(3759952..3760830) Escherichia coli BW2952 7952267 YP_002928581.1 CDS dgoR NC_012759.1 3760827 3761516 R MG1655 equivalent: b4479; putative DNA-binding transcriptional regulator complement(3760827..3761516) Escherichia coli BW2952 7952268 YP_002928582.1 CDS yidX NC_012759.1 3761794 3762450 D MG1655 equivalent: b3696; hypothetical protein 3761794..3762450 Escherichia coli BW2952 7954788 YP_002928583.1 CDS yidA NC_012759.1 3762496 3763308 R YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase complement(3762496..3763308) Escherichia coli BW2952 7955122 YP_002928584.1 CDS yidB NC_012759.1 3763423 3763821 R MG1655 equivalent: b3698; hypothetical protein complement(3763423..3763821) Escherichia coli BW2952 7954961 YP_002928585.1 CDS gyrB NC_012759.1 3764061 3766475 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(3764061..3766475) Escherichia coli BW2952 7952890 YP_002928586.1 CDS recF NC_012759.1 3766504 3767577 R Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F complement(3766504..3767577) Escherichia coli BW2952 7953308 YP_002928587.1 CDS dnaN NC_012759.1 3767577 3768677 R binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta complement(3767577..3768677) Escherichia coli BW2952 7953774 YP_002928588.1 CDS dnaA NC_012759.1 3768682 3770085 R binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein complement(3768682..3770085) Escherichia coli BW2952 7953320 YP_002928589.1 CDS rpmH NC_012759.1 3770692 3770832 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 3770692..3770832 Escherichia coli BW2952 7952638 YP_002928590.1 CDS rnpA NC_012759.1 3770849 3771208 D protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 3770849..3771208 Escherichia coli BW2952 7952362 YP_002928591.1 CDS yidD NC_012759.1 3771172 3771429 D MG1655 equivalent: b4557; hypothetical protein 3771172..3771429 Escherichia coli BW2952 7955784 YP_002928592.1 CDS yidC NC_012759.1 3771432 3773078 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 3771432..3773078 Escherichia coli BW2952 7955538 YP_002928593.1 CDS trmE NC_012759.1 3773184 3774548 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 3773184..3774548 Escherichia coli BW2952 7953201 YP_002928594.1 CDS tnaC NC_012759.1 3774791 3774865 D MG1655 equivalent: b3707; tryptophanase leader peptide 3774791..3774865 Escherichia coli BW2952 7953878 YP_002928595.1 CDS tnaA NC_012759.1 3775086 3776501 D tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 3775086..3776501 Escherichia coli BW2952 7956215 YP_002928596.1 CDS tnaB NC_012759.1 3776592 3777839 D tryptophan transporter of low affinity; tryptophan permease TnaB 3776592..3777839 Escherichia coli BW2952 7956216 YP_002928597.1 CDS mdtL NC_012759.1 3777971 3779146 D Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 3777971..3779146 Escherichia coli BW2952 7956214 YP_002928598.1 CDS yidZ NC_012759.1 3779121 3780080 D Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 3779121..3780080 Escherichia coli BW2952 7954306 YP_002928599.1 CDS yieE NC_012759.1 3780225 3780986 D MG1655 equivalent: b3712; putative phosphopantetheinyl transferase 3780225..3780986 Escherichia coli BW2952 7954815 YP_002928600.1 CDS yieF NC_012759.1 3781008 3781574 D MG1655 equivalent: b3713; chromate reductase, Class I, flavoprotein 3781008..3781574 Escherichia coli BW2952 7955317 YP_002928601.1 CDS yieG NC_012759.1 3781628 3782965 R MG1655 equivalent: b3714; putative inner membrane protein complement(3781628..3782965) Escherichia coli BW2952 7952637 YP_002928602.1 CDS yieH NC_012759.1 3783130 3783795 D YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 3783130..3783795 Escherichia coli BW2952 7955014 YP_002928603.1 CDS cbrB NC_012759.1 3783862 3784329 D might be involved in hypersensitivity to nitrofurzone; putative inner membrane protein 3783862..3784329 Escherichia coli BW2952 7954971 YP_002928604.1 CDS cbrC NC_012759.1 3784378 3784965 D MG1655 equivalent: b3717; hypothetical protein 3784378..3784965 Escherichia coli BW2952 7955071 YP_002928605.1 CDS yieK NC_012759.1 3785027 3785749 R MG1655 equivalent: b3718; putative 6-phosphogluconolactonase complement(3785027..3785749) Escherichia coli BW2952 7953039 YP_002928606.1 CDS yieL NC_012759.1 3785764 3786933 R MG1655 equivalent: b3719; putative xylanase complement(3785764..3786933) Escherichia coli BW2952 7954598 YP_002928607.1 CDS bglH NC_012759.1 3786960 3788576 R MG1655 equivalent: b3720; carbohydrate-specific outer membrane porin, cryptic complement(3786960..3788576) Escherichia coli BW2952 7955753 YP_002928608.1 CDS bglB NC_012759.1 3788645 3790057 R MG1655 equivalent: b3721; cryptic phospho-beta-glucosidase B complement(3788645..3790057) Escherichia coli BW2952 7952595 YP_002928609.1 CDS bglF NC_012759.1 3790076 3791953 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system beta-glucoside-specific transporter subunit IIABC complement(3790076..3791953) Escherichia coli BW2952 7953171 YP_002928610.1 CDS bglG NC_012759.1 3792087 3792923 R positive regulator of the beta-glucoside operon; transcriptional antiterminator; transcriptional antiterminator BglG complement(3792087..3792923) Escherichia coli BW2952 7953659 YP_002928611.1 CDS phoU NC_012759.1 3793209 3793934 R regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU complement(3793209..3793934) Escherichia coli BW2952 7956172 YP_002928612.1 CDS pstB NC_012759.1 3793949 3794722 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(3793949..3794722) Escherichia coli BW2952 7954371 YP_002928613.1 CDS pstA NC_012759.1 3794905 3795795 R Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA complement(3794905..3795795) Escherichia coli BW2952 7954515 YP_002928614.1 CDS pstC NC_012759.1 3795795 3796754 R part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC complement(3795795..3796754) Escherichia coli BW2952 7954516 YP_002928615.1 CDS pstS NC_012759.1 3796841 3797881 R MG1655 equivalent: b3728; phosphate ABC transporter substrate-binding protein complement(3796841..3797881) Escherichia coli BW2952 7954517 YP_002928616.1 CDS glmS NC_012759.1 3798195 3800024 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(3798195..3800024) Escherichia coli BW2952 7954518 YP_002928617.1 CDS glmU NC_012759.1 3800186 3801556 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(3800186..3801556) Escherichia coli BW2952 7954141 YP_002928618.1 CDS atpC NC_012759.1 3801909 3802328 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(3801909..3802328) Escherichia coli BW2952 7953703 YP_002928619.1 CDS atpD NC_012759.1 3802349 3803731 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(3802349..3803731) Escherichia coli BW2952 7953559 YP_002928620.1 CDS atpG NC_012759.1 3803758 3804621 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(3803758..3804621) Escherichia coli BW2952 7953557 YP_002928621.1 CDS atpA NC_012759.1 3804672 3806213 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(3804672..3806213) Escherichia coli BW2952 7953560 YP_002928622.1 CDS atpH NC_012759.1 3806226 3806759 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(3806226..3806759) Escherichia coli BW2952 7953556 YP_002928623.1 CDS atpF NC_012759.1 3806774 3807244 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B complement(3806774..3807244) Escherichia coli BW2952 7953558 YP_002928624.1 CDS atpE NC_012759.1 3807306 3807545 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C complement(3807306..3807545) Escherichia coli BW2952 7953554 YP_002928625.1 CDS atpB NC_012759.1 3807592 3808407 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(3807592..3808407) Escherichia coli BW2952 7953555 YP_002928626.1 CDS atpI NC_012759.1 3808416 3808796 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I complement(3808416..3808796) Escherichia coli BW2952 7953553 YP_002928627.1 CDS gidB NC_012759.1 3809413 3810036 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(3809413..3810036) Escherichia coli BW2952 7952522 YP_002928628.1 CDS mnmG NC_012759.1 3810100 3811989 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(3810100..3811989) Escherichia coli BW2952 7954262 YP_002928629.1 CDS mioC NC_012759.1 3812368 3812811 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(3812368..3812811) Escherichia coli BW2952 7953810 YP_002928630.1 CDS asnC NC_012759.1 3812901 3813359 R transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC complement(3812901..3813359) Escherichia coli BW2952 7953613 YP_002928631.1 CDS asnA NC_012759.1 3813511 3814503 D catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 3813511..3814503 Escherichia coli BW2952 7953412 YP_002928632.1 CDS yieM NC_012759.1 3814508 3815959 R contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein complement(3814508..3815959) Escherichia coli BW2952 7952507 YP_002928633.1 CDS ravA NC_012759.1 3815953 3817449 R interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA complement(3815953..3817449) Escherichia coli BW2952 7955750 YP_002928634.1 CDS trkD NC_012759.1 3817672 3819540 D Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 3817672..3819540 Escherichia coli BW2952 7953729 YP_002928635.1 CDS rbsD NC_012759.1 3819707 3820126 D cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 3819707..3820126 Escherichia coli BW2952 7954576 YP_002928636.1 CDS rbsA NC_012759.1 3820134 3821639 D with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP-binding protein 3820134..3821639 Escherichia coli BW2952 7954710 YP_002928637.1 CDS rbsC NC_012759.1 3821644 3822609 D functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 3821644..3822609 Escherichia coli BW2952 7953677 YP_002928638.1 CDS rbsB NC_012759.1 3822634 3823524 D periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 3822634..3823524 Escherichia coli BW2952 7953493 YP_002928639.1 CDS rbsK NC_012759.1 3823650 3824579 D catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 3823650..3824579 Escherichia coli BW2952 7953494 YP_002928640.1 CDS BWG_3445 NC_012759.1 3825220 3825585 D IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 3825220..3825585 Escherichia coli BW2952 7955918 YP_002928641.1 CDS BWG_3446 NC_012759.1 3825543 3826448 D IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 3825543..3826448 Escherichia coli BW2952 7954008 YP_002928642.1 CDS hsrA NC_012759.1 3826877 3828304 R MG1655 equivalent: b3754; putative multidrug or homocysteine efflux system complement(3826877..3828304) Escherichia coli BW2952 7952209 YP_002928643.1 CDS yieP NC_012759.1 3828327 3829019 R MG1655 equivalent: b3755; putative transcriptional regulator complement(3828327..3829019) Escherichia coli BW2952 7955175 YP_002928644.1 CDS hdfR NC_012759.1 3834820 3835659 R Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR complement(3834820..3835659) Escherichia coli BW2952 7952150 YP_002928645.1 CDS yifE NC_012759.1 3835778 3836116 D MG1655 equivalent: b3764; hypothetical protein 3835778..3836116 Escherichia coli BW2952 7953441 YP_002928646.1 CDS yifB NC_012759.1 3836141 3837661 R among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function; putative ATP-dependent protease complement(3836141..3837661) Escherichia coli BW2952 7953040 YP_002928647.1 CDS ilvL NC_012759.1 3838014 3838112 D MG1655 equivalent: b3766; ilvG operon leader peptide 3838014..3838112 Escherichia coli BW2952 7954670 YP_002928648.1 CDS ilvM NC_012759.1 3839893 3840156 D MG1655 equivalent: b3769; acetolactate synthase 2 regulatory subunit 3839893..3840156 Escherichia coli BW2952 7953990 YP_002928649.1 CDS ilvE NC_012759.1 3840176 3841105 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 3840176..3841105 Escherichia coli BW2952 7952392 YP_002928650.1 CDS ilvD NC_012759.1 3841170 3843020 D catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 3841170..3843020 Escherichia coli BW2952 7952583 YP_002928651.1 CDS ilvA NC_012759.1 3843023 3844567 D threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 3843023..3844567 Escherichia coli BW2952 7953259 YP_002928652.1 CDS ilvY NC_012759.1 3844619 3845512 R participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY complement(3844619..3845512) Escherichia coli BW2952 7956144 YP_002928653.1 CDS ilvC NC_012759.1 3845662 3847137 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 3845662..3847137 Escherichia coli BW2952 7953413 YP_002928654.1 CDS ppiC NC_012759.1 3847224 3847505 R MG1655 equivalent: b3775; peptidyl-prolyl cis-trans isomerase C complement(3847224..3847505) Escherichia coli BW2952 7954060 YP_002928655.1 CDS rep NC_012759.1 3848369 3850390 D single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 3848369..3850390 Escherichia coli BW2952 7954484 YP_002928656.1 CDS gpp NC_012759.1 3850437 3851921 R catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase complement(3850437..3851921) Escherichia coli BW2952 7953309 YP_002928657.1 CDS rhlB NC_012759.1 3852057 3853322 R enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB complement(3852057..3853322) Escherichia coli BW2952 7953886 YP_002928658.1 CDS trxA NC_012759.1 3853453 3853782 D MG1655 equivalent: b3781; thioredoxin 3853453..3853782 Escherichia coli BW2952 7952535 YP_002928659.1 CDS rho NC_012759.1 3854109 3855368 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 3854109..3855368 Escherichia coli BW2952 7956134 YP_002928660.1 CDS rfe NC_012759.1 3855608 3856711 D MG1655 equivalent: b3784; UDP-GlcNAc:UDPphosphate GlcNAc-1-phosphate transferase 3855608..3856711 Escherichia coli BW2952 7956169 YP_002928661.1 CDS wzzE NC_012759.1 3856723 3857769 D Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 3856723..3857769 Escherichia coli BW2952 7956233 YP_002928662.1 CDS rffE NC_012759.1 3857825 3858955 D MG1655 equivalent: b3786; UDP-N-acetyl glucosamine-2-epimerase 3857825..3858955 Escherichia coli BW2952 7953529 YP_002928663.1 CDS wecC NC_012759.1 3858952 3860214 D catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 3858952..3860214 Escherichia coli BW2952 7956235 YP_002928664.1 CDS rffG NC_012759.1 3860214 3861281 D MG1655 equivalent: b3788; dTDP-glucose 4,6-dehydratase 3860214..3861281 Escherichia coli BW2952 7956236 YP_002928665.1 CDS rffH NC_012759.1 3861300 3862181 D MG1655 equivalent: b3789; glucose-1-phosphate thymidylyltransferase 3861300..3862181 Escherichia coli BW2952 7953504 YP_002928666.1 CDS rffC NC_012759.1 3862159 3862833 D MG1655 equivalent: b3790; TDP-fucosamine acetyltransferase 3862159..3862833 Escherichia coli BW2952 7953807 YP_002928667.1 CDS rffA NC_012759.1 3862838 3863968 D catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 3862838..3863968 Escherichia coli BW2952 7956119 YP_002928668.1 CDS wzxE NC_012759.1 3863970 3865220 D MG1655 equivalent: b3792; O-antigen translocase 3863970..3865220 Escherichia coli BW2952 7956117 YP_002928669.1 CDS rffT NC_012759.1 3865217 3866296 D catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 3865217..3866296 Escherichia coli BW2952 7954419 YP_002928670.1 CDS wzyE NC_012759.1 3866293 3867645 D enterobacterial common antigen polymerase; putative common antigen polymerase 3866293..3867645 Escherichia coli BW2952 7956118 YP_002928671.1 CDS rffM NC_012759.1 3867648 3868388 D MG1655 equivalent: b3794; putative UDP-N-acetyl-D-mannosaminuronic acid transferase 3867648..3868388 Escherichia coli BW2952 7955751 YP_002928672.1 CDS yifK NC_012759.1 3868579 3869964 D uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; putative transport protein YifK 3868579..3869964 Escherichia coli BW2952 7956237 YP_002928673.1 CDS aslB NC_012759.1 3870650 3871885 D MG1655 equivalent: b3800; putative regulator of arylsulfatase activity 3870650..3871885 Escherichia coli BW2952 7952154 YP_002928674.1 CDS aslA NC_012759.1 3872044 3873699 R MG1655 equivalent: b3801; acrylsulfatase-like enzyme complement(3872044..3873699) Escherichia coli BW2952 7955562 YP_002928675.1 CDS hemY NC_012759.1 3874378 3875574 R MG1655 equivalent: b3802; putative protoheme IX biogenesis protein complement(3874378..3875574) Escherichia coli BW2952 7952198 YP_002928676.1 CDS hemX NC_012759.1 3875577 3876758 R MG1655 equivalent: b3803; putative uroporphyrinogen III C-methyltransferase complement(3875577..3876758) Escherichia coli BW2952 7955547 YP_002928677.1 CDS hemD NC_012759.1 3876780 3877520 R catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase complement(3876780..3877520) Escherichia coli BW2952 7955748 YP_002928678.1 CDS hemC NC_012759.1 3877517 3878458 R transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase complement(3877517..3878458) Escherichia coli BW2952 7956268 YP_002928679.1 CDS cyaA NC_012759.1 3878845 3881391 D catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 3878845..3881391 Escherichia coli BW2952 7953959 YP_002928680.1 CDS cyaY NC_012759.1 3881431 3881751 R defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein complement(3881431..3881751) Escherichia coli BW2952 7952422 YP_002928681.1 CDS yifL NC_012759.1 3882214 3882417 D MG1655 equivalent: b4558; putative lipoprotein 3882214..3882417 Escherichia coli BW2952 7953631 YP_002928682.1 CDS dapF NC_012759.1 3882454 3883278 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 3882454..3883278 Escherichia coli BW2952 7955119 YP_002928683.1 CDS xerC NC_012759.1 3883979 3884875 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 3883979..3884875 Escherichia coli BW2952 7953248 YP_002928684.1 CDS yigB NC_012759.1 3884875 3885591 D YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 3884875..3885591 Escherichia coli BW2952 7956048 YP_002928685.1 CDS uvrD NC_012759.1 3885675 3887837 D unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 3885675..3887837 Escherichia coli BW2952 7954972 YP_002928686.1 CDS yigE NC_012759.1 3887984 3888748 R MG1655 equivalent: b4482; hypothetical protein complement(3887984..3888748) Escherichia coli BW2952 7953487 YP_002928687.1 CDS corA NC_012759.1 3889118 3890068 D responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 3889118..3890068 Escherichia coli BW2952 7955431 YP_002928688.1 CDS yigF NC_012759.1 3890111 3890491 R MG1655 equivalent: b3817; hypothetical protein complement(3890111..3890491) Escherichia coli BW2952 7954192 YP_002928689.1 CDS yigG NC_012759.1 3890505 3890885 R MG1655 equivalent: b3818; hypothetical protein complement(3890505..3890885) Escherichia coli BW2952 7952691 YP_002928690.1 CDS rarD NC_012759.1 3890980 3891870 R MG1655 equivalent: b3819; putative chloramphenical resistance permease complement(3890980..3891870) Escherichia coli BW2952 7955015 YP_002928691.1 CDS yigI NC_012759.1 3891922 3892389 R MG1655 equivalent: b3820; hypothetical protein complement(3891922..3892389) Escherichia coli BW2952 7954692 YP_002928692.1 CDS pldA NC_012759.1 3892554 3893423 D catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 3892554..3893423 Escherichia coli BW2952 7952891 YP_002928693.1 CDS recQ NC_012759.1 3893556 3895385 D functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 3893556..3895385 Escherichia coli BW2952 7954441 YP_002928694.1 CDS rhtC NC_012759.1 3895449 3896069 D MG1655 equivalent: b3823; threonine efflux system 3895449..3896069 Escherichia coli BW2952 7952531 YP_002928695.1 CDS rhtB NC_012759.1 3896131 3896751 R MG1655 equivalent: b3824; homoserine/homoserine lactone efflux protein complement(3896131..3896751) Escherichia coli BW2952 7956145 YP_002928696.1 CDS pldB NC_012759.1 3896862 3897884 D lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 3896862..3897884 Escherichia coli BW2952 7954374 YP_002928697.1 CDS yigL NC_012759.1 3897892 3898692 D purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; putative sugar phosphatase 3897892..3898692 Escherichia coli BW2952 7954186 YP_002928698.1 CDS yigM NC_012759.1 3898768 3899667 D MG1655 equivalent: b3827; putative inner membrane protein 3898768..3899667 Escherichia coli BW2952 7954973 YP_002928699.1 CDS metR NC_012759.1 3899555 3900508 R MG1655 equivalent: b3828; DNA-binding transcriptional activator, homocysteine-binding complement(3899555..3900508) Escherichia coli BW2952 7955072 YP_002928700.1 CDS metE NC_012759.1 3900745 3903006 D catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 3900745..3903006 Escherichia coli BW2952 7953397 YP_002928701.1 CDS ysgA NC_012759.1 3903046 3903861 R MG1655 equivalent: b3830; putative hydrolase complement(3903046..3903861) Escherichia coli BW2952 7952374 YP_002928702.1 CDS udp NC_012759.1 3904123 3904884 D catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 3904123..3904884 Escherichia coli BW2952 7954962 YP_002928703.1 CDS rmuC NC_012759.1 3905025 3906452 D YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 3905025..3906452 Escherichia coli BW2952 7956262 YP_002928704.1 CDS ubiE NC_012759.1 3906547 3907302 D Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 3906547..3907302 Escherichia coli BW2952 7955556 YP_002928705.1 CDS yigP NC_012759.1 3907316 3907921 D MG1655 equivalent: b3834; hypothetical protein 3907316..3907921 Escherichia coli BW2952 7952556 YP_002928706.1 CDS ubiB NC_012759.1 3907918 3909558 D an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; putative ubiquinone biosynthesis protein UbiB 3907918..3909558 Escherichia coli BW2952 7953041 YP_002928707.1 CDS tatA NC_012759.1 3909637 3909906 D TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 3909637..3909906 Escherichia coli BW2952 7952266 YP_002928708.1 CDS tatB NC_012759.1 3909910 3910425 D mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 3909910..3910425 Escherichia coli BW2952 7956110 YP_002928709.1 CDS tatC NC_012759.1 3910428 3911204 D with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 3910428..3911204 Escherichia coli BW2952 7956111 YP_002928710.1 CDS tatD NC_012759.1 3911246 3912028 D magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 3911246..3912028 Escherichia coli BW2952 7956112 YP_002928711.1 CDS rfaH NC_012759.1 3912025 3912513 R MG1655 equivalent: b3842; transcriptional activator RfaH complement(3912025..3912513) Escherichia coli BW2952 7953491 YP_002928712.1 CDS ubiD NC_012759.1 3912680 3914173 D catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 3912680..3914173 Escherichia coli BW2952 7953402 YP_002928713.1 CDS fre NC_012759.1 3914219 3914920 D NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 3914219..3914920 Escherichia coli BW2952 7952316 YP_002928714.1 CDS fadA NC_012759.1 3915301 3916464 R FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase complement(3915301..3916464) Escherichia coli BW2952 7953608 YP_002928715.1 CDS fadB NC_012759.1 3916474 3918663 R includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha complement(3916474..3918663) Escherichia coli BW2952 7952308 YP_002928716.1 CDS pepQ NC_012759.1 3918853 3920184 D catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 3918853..3920184 Escherichia coli BW2952 7953650 YP_002928717.1 CDS yigZ NC_012759.1 3920184 3920798 D MG1655 equivalent: b3848; hypothetical protein 3920184..3920798 Escherichia coli BW2952 7955768 YP_002928718.1 CDS trkH NC_012759.1 3920837 3922288 D MG1655 equivalent: b3849; potassium transporter 3920837..3922288 Escherichia coli BW2952 7954832 YP_002928719.1 CDS hemG NC_012759.1 3922300 3922845 D catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 3922300..3922845 Escherichia coli BW2952 7954577 YP_002928720.1 CDS mobB NC_012759.1 3928598 3929125 R in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein B complement(3928598..3929125) Escherichia coli BW2952 7952108 YP_002928721.1 CDS mobA NC_012759.1 3929107 3929691 R in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA complement(3929107..3929691) Escherichia coli BW2952 7954294 YP_002928722.1 CDS yihD NC_012759.1 3929761 3930030 D MG1655 equivalent: b3858; hypothetical protein 3929761..3930030 Escherichia coli BW2952 7954295 YP_002928723.1 CDS rdoA NC_012759.1 3930107 3931093 D catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 3930107..3931093 Escherichia coli BW2952 7953042 YP_002928724.1 CDS dsbA NC_012759.1 3931110 3931736 D MG1655 equivalent: b3860; protein disulfide isomerase I 3931110..3931736 Escherichia coli BW2952 7956141 YP_002928725.1 CDS yihF NC_012759.1 3931891 3933321 D MG1655 equivalent: b3861; hypothetical protein 3931891..3933321 Escherichia coli BW2952 7954499 YP_002928726.1 CDS yihG NC_012759.1 3933362 3934294 R MG1655 equivalent: b3862; putative acyltransferase complement(3933362..3934294) Escherichia coli BW2952 7953043 YP_002928727.1 CDS polA NC_012759.1 3934658 3937444 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 3934658..3937444 Escherichia coli BW2952 7954834 YP_002928728.1 CDS engB NC_012759.1 3937825 3938457 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(3937825..3938457) Escherichia coli BW2952 7952199 YP_002928729.1 CDS yihI NC_012759.1 3939039 3939548 D MG1655 equivalent: b3866; hypothetical protein 3939039..3939548 Escherichia coli BW2952 7952200 YP_002928730.1 CDS hemN NC_012759.1 3939737 3941110 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3939737..3941110 Escherichia coli BW2952 7953044 YP_002928731.1 CDS glnG NC_012759.1 3941561 3942970 R response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) complement(3941561..3942970) Escherichia coli BW2952 7953102 YP_002928732.1 CDS glnL NC_012759.1 3942982 3944031 R sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) complement(3942982..3944031) Escherichia coli BW2952 7953673 YP_002928733.1 CDS glnA NC_012759.1 3944317 3945726 R forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase complement(3944317..3945726) Escherichia coli BW2952 7956019 YP_002928734.1 CDS typA NC_012759.1 3946099 3947922 D MG1655 equivalent: b3871; GTP-binding protein 3946099..3947922 Escherichia coli BW2952 7953827 YP_002928735.1 CDS yihL NC_012759.1 3948139 3948849 D MG1655 equivalent: b3872; putative DNA-binding transcriptional regulator 3948139..3948849 Escherichia coli BW2952 7953882 YP_002928736.1 CDS yihM NC_012759.1 3948857 3949837 D MG1655 equivalent: b3873; putative sugar phosphate isomerase 3948857..3949837 Escherichia coli BW2952 7954816 YP_002928737.1 CDS yihN NC_012759.1 3949939 3951204 D MG1655 equivalent: b3874; putative transporter 3949939..3951204 Escherichia coli BW2952 7955605 YP_002928738.1 CDS ompL NC_012759.1 3951295 3951987 R porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown; outer membrane porin L complement(3951295..3951987) Escherichia coli BW2952 7955713 YP_002928739.1 CDS yihO NC_012759.1 3952055 3953458 R MG1655 equivalent: b3876; putative transporter complement(3952055..3953458) Escherichia coli BW2952 7955207 YP_002928740.1 CDS yihP NC_012759.1 3953501 3954886 R MG1655 equivalent: b3877; putative transporter complement(3953501..3954886) Escherichia coli BW2952 7955672 YP_002928741.1 CDS yihQ NC_012759.1 3954932 3956968 R MG1655 equivalent: b3878; alpha-glucosidase complement(3954932..3956968) Escherichia coli BW2952 7955673 YP_002928742.1 CDS yihR NC_012759.1 3957167 3958093 R MG1655 equivalent: b3879; putative aldose-1-epimerase complement(3957167..3958093) Escherichia coli BW2952 7952458 YP_002928743.1 CDS yihS NC_012759.1 3958207 3959448 R MG1655 equivalent: b3880; putative glucosamine isomerase complement(3958207..3959448) Escherichia coli BW2952 7954631 YP_002928744.1 CDS yihT NC_012759.1 3959465 3960343 R MG1655 equivalent: b3881; putative aldolase complement(3959465..3960343) Escherichia coli BW2952 7954919 YP_002928745.1 CDS yihU NC_012759.1 3960367 3961263 R MG1655 equivalent: b3882; putative oxidoreductase with NAD(P)-binding Rossmann-fold domain complement(3960367..3961263) Escherichia coli BW2952 7954630 YP_002928746.1 CDS yihV NC_012759.1 3961431 3962327 D MG1655 equivalent: b3883; putative sugar kinase 3961431..3962327 Escherichia coli BW2952 7955248 YP_002928747.1 CDS yihW NC_012759.1 3962361 3963146 D MG1655 equivalent: b3884; putative DNA-binding transcriptional regulator 3962361..3963146 Escherichia coli BW2952 7955604 YP_002928748.1 CDS yihX NC_012759.1 3963245 3963844 D MG1655 equivalent: b3885; phosphatase 3963245..3963844 Escherichia coli BW2952 7954817 YP_002928749.1 CDS rbn NC_012759.1 3963838 3964710 D RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 3963838..3964710 Escherichia coli BW2952 7954974 YP_002928750.1 CDS dtd NC_012759.1 3964707 3965144 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 3964707..3965144 Escherichia coli BW2952 7955073 YP_002928751.1 CDS yiiD NC_012759.1 3965141 3966130 D MG1655 equivalent: b3888; putative acetyltransferase 3965141..3966130 Escherichia coli BW2952 7953505 YP_002928752.1 CDS yiiE NC_012759.1 3966989 3967201 D MG1655 equivalent: b3889; putative transcriptional regulator 3966989..3967201 Escherichia coli BW2952 7954604 YP_002928753.1 CDS yiiF NC_012759.1 3967443 3967661 D MG1655 equivalent: b3890; hypothetical protein 3967443..3967661 Escherichia coli BW2952 7955639 YP_002928754.1 CDS fdhE NC_012759.1 3967991 3968920 R required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE complement(3967991..3968920) Escherichia coli BW2952 7953045 YP_002928755.1 CDS fdoI NC_012759.1 3968917 3969552 R cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma complement(3968917..3969552) Escherichia coli BW2952 7953615 YP_002928756.1 CDS fdoH NC_012759.1 3969549 3970451 R MG1655 equivalent: b3893; formate dehydrogenase-O, Fe-S subunit complement(3969549..3970451) Escherichia coli BW2952 7953622 YP_002928757.1 CDS fdoG NC_012759.1 3970464 3973514 R MG1655 equivalent: b3894; formate dehydrogenase-O, large subunit complement(3970464..3973514) Escherichia coli BW2952 7953623 YP_002928758.1 CDS fdhD NC_012759.1 3973708 3974541 D involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 3973708..3974541 Escherichia coli BW2952 7953624 YP_002928759.1 CDS yiiG NC_012759.1 3974694 3975749 D MG1655 equivalent: b3896; hypothetical protein 3974694..3975749 Escherichia coli BW2952 7953616 YP_002928760.1 CDS frvR NC_012759.1 3975799 3977547 R putative repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system; putative frv operon regulatory protein complement(3975799..3977547) Escherichia coli BW2952 7953046 YP_002928761.1 CDS frvX NC_012759.1 3977547 3978617 R with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars; putative fructose-specific phosphotransferase system protein FrvX complement(3977547..3978617) Escherichia coli BW2952 7955559 YP_002928762.1 CDS frvB NC_012759.1 3978607 3980058 R MG1655 equivalent: b3899; putative PTS system transporter subunits IIBC complement(3978607..3980058) Escherichia coli BW2952 7954833 YP_002928763.1 CDS frvA NC_012759.1 3980069 3980515 R with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system; putative fructose-like phosphotransferase system subunit EIIA complement(3980069..3980515) Escherichia coli BW2952 7953725 YP_002928764.1 CDS rhaM NC_012759.1 3980816 3981130 R MG1655 equivalent: b3901; L-rhamnose mutarotase complement(3980816..3981130) Escherichia coli BW2952 7954851 YP_002928765.1 CDS rhaD NC_012759.1 3981140 3981964 R MG1655 equivalent: b3902; rhamnulose-1-phosphate aldolase complement(3981140..3981964) Escherichia coli BW2952 7954165 YP_002928766.1 CDS rhaA NC_012759.1 3982415 3983674 R catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase complement(3982415..3983674) Escherichia coli BW2952 7955947 YP_002928767.1 CDS rhaB NC_012759.1 3983671 3985140 R catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase complement(3983671..3985140) Escherichia coli BW2952 7954164 YP_002928768.1 CDS rhaS NC_012759.1 3985428 3986264 D activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 3985428..3986264 Escherichia coli BW2952 7955946 YP_002928769.1 CDS rhaR NC_012759.1 3986338 3987186 D activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 3986338..3987186 Escherichia coli BW2952 7953398 YP_002928770.1 CDS rhaT NC_012759.1 3987183 3988217 R transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter complement(3987183..3988217) Escherichia coli BW2952 7953399 YP_002928771.1 CDS sodA NC_012759.1 3988502 3989122 D SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 3988502..3989122 Escherichia coli BW2952 7954166 YP_002928772.1 CDS kdgT NC_012759.1 3989382 3990365 D transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 3989382..3990365 Escherichia coli BW2952 7956101 YP_002928773.1 CDS yiiM NC_012759.1 3990514 3991188 D MG1655 equivalent: b3910; hypothetical protein 3990514..3991188 Escherichia coli BW2952 7952260 YP_002928774.1 CDS cpxA NC_012759.1 3991294 3992667 R part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein complement(3991294..3992667) Escherichia coli BW2952 7953047 YP_002928775.1 CDS cpxR NC_012759.1 3992664 3993362 R response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR complement(3992664..3993362) Escherichia coli BW2952 7956015 YP_002928776.1 CDS cpxP NC_012759.1 3993512 3994012 D repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; repressor CpxP 3993512..3994012 Escherichia coli BW2952 7953348 YP_002928777.1 CDS fieF NC_012759.1 3994161 3995063 D member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 3994161..3995063 Escherichia coli BW2952 7954498 YP_002928778.1 CDS pfkA NC_012759.1 3995244 3996206 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 3995244..3996206 Escherichia coli BW2952 7956285 YP_002928779.1 CDS sbp NC_012759.1 3996526 3997515 D MG1655 equivalent: b3917; sulfate transporter subunit 3996526..3997515 Escherichia coli BW2952 7952377 YP_002928780.1 CDS cdh NC_012759.1 3997622 3998377 D MG1655 equivalent: b3918; CDP-diacylglycerol pyrophosphatase 3997622..3998377 Escherichia coli BW2952 7956090 YP_002928781.1 CDS tpiA NC_012759.1 3998432 3999199 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(3998432..3999199) Escherichia coli BW2952 7952612 YP_002928782.1 CDS yiiQ NC_012759.1 3999307 3999906 R MG1655 equivalent: b3920; hypothetical protein complement(3999307..3999906) Escherichia coli BW2952 7956193 YP_002928783.1 CDS yiiR NC_012759.1 4000007 4000447 D MG1655 equivalent: b3921; hypothetical protein 4000007..4000447 Escherichia coli BW2952 7952892 YP_002928784.1 CDS yiiS NC_012759.1 4000659 4000958 D MG1655 equivalent: b3922; hypothetical protein 4000659..4000958 Escherichia coli BW2952 7952732 YP_002928785.1 CDS uspD NC_012759.1 4000985 4001413 D with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 4000985..4001413 Escherichia coli BW2952 7953048 YP_002928786.1 CDS fpr NC_012759.1 4001418 4002164 R MG1655 equivalent: b3924; ferredoxin-NADP reductase complement(4001418..4002164) Escherichia coli BW2952 7956073 YP_002928787.1 CDS glpX NC_012759.1 4002261 4003271 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(4002261..4003271) Escherichia coli BW2952 7953564 YP_002928788.1 CDS glpK NC_012759.1 4003406 4004914 R Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase complement(4003406..4004914) Escherichia coli BW2952 7953633 YP_002928789.1 CDS glpF NC_012759.1 4004937 4005782 R MG1655 equivalent: b3927; glycerol facilitator complement(4004937..4005782) Escherichia coli BW2952 7953847 YP_002928790.1 CDS yiiU NC_012759.1 4006207 4006452 D MG1655 equivalent: b3928; hypothetical protein 4006207..4006452 Escherichia coli BW2952 7953846 YP_002928791.1 CDS rraA NC_012759.1 4006537 4007022 R regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA complement(4006537..4007022) Escherichia coli BW2952 7953049 YP_002928792.1 CDS menA NC_012759.1 4007115 4008041 R catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase complement(4007115..4008041) Escherichia coli BW2952 7955957 YP_002928793.1 CDS hslU NC_012759.1 4008108 4009439 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU complement(4008108..4009439) Escherichia coli BW2952 7952220 YP_002928794.1 CDS hslV NC_012759.1 4009449 4009979 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit complement(4009449..4009979) Escherichia coli BW2952 7954281 YP_002928795.1 CDS ftsN NC_012759.1 4010072 4011031 R MG1655 equivalent: b3933; essential cell division protein FtsN complement(4010072..4011031) Escherichia coli BW2952 7954472 YP_002928796.1 CDS cytR NC_012759.1 4011123 4012148 R negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR complement(4011123..4012148) Escherichia coli BW2952 7953532 YP_002928797.1 CDS priA NC_012759.1 4012304 4014502 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(4012304..4014502) Escherichia coli BW2952 7953414 YP_002928798.1 CDS rpmE NC_012759.1 4014705 4014917 D RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 4014705..4014917 Escherichia coli BW2952 7955766 YP_002928799.1 CDS yiiX NC_012759.1 4014978 4015586 R member of the NlpC/P60 superfamily of peptidases; putative peptidoglycan peptidase complement(4014978..4015586) Escherichia coli BW2952 7952359 YP_002928800.1 CDS metJ NC_012759.1 4015770 4016087 R when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ complement(4015770..4016087) Escherichia coli BW2952 7955296 YP_002928801.1 CDS metB NC_012759.1 4016364 4017524 D catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 4016364..4017524 Escherichia coli BW2952 7953481 YP_002928802.1 CDS metL NC_012759.1 4017527 4019959 D multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 4017527..4019959 Escherichia coli BW2952 7953180 YP_002928803.1 CDS metF NC_012759.1 4020308 4021198 D MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 4020308..4021198 Escherichia coli BW2952 7953658 YP_002928804.1 CDS katG NC_012759.1 4021527 4023707 D MG1655 equivalent: b3942; catalase/hydroperoxidase HPI(I) 4021527..4023707 Escherichia coli BW2952 7952336 YP_002928805.1 CDS yijE NC_012759.1 4023800 4024705 D MG1655 equivalent: b3943; putative permease 4023800..4024705 Escherichia coli BW2952 7952611 YP_002928806.1 CDS yijF NC_012759.1 4024732 4025349 R MG1655 equivalent: b3944; hypothetical protein complement(4024732..4025349) Escherichia coli BW2952 7955308 YP_002928807.1 CDS gldA NC_012759.1 4025624 4026727 R forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase complement(4025624..4026727) Escherichia coli BW2952 7952893 YP_002928808.1 CDS fsaB NC_012759.1 4026738 4027400 R similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase complement(4026738..4027400) Escherichia coli BW2952 7953845 YP_002928809.1 CDS ptsA NC_012759.1 4027412 4029913 R MG1655 equivalent: b3947; fused putative PTS enzymes: Hpr component/enzyme I component/enzyme IIA component complement(4027412..4029913) Escherichia coli BW2952 7953636 YP_002928810.1 CDS frwC NC_012759.1 4030222 4031301 D FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; putative fructose-like permease EIIC subunit 2 4030222..4031301 Escherichia coli BW2952 7953724 YP_002928811.1 CDS frwB NC_012759.1 4031316 4031636 D FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; putative PTS system fructose-like transporter subunit EIIB 4031316..4031636 Escherichia coli BW2952 7954857 YP_002928812.1 CDS pflD NC_012759.1 4031687 4033984 D involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; putative formate acetyltransferase 2 4031687..4033984 Escherichia coli BW2952 7954854 YP_002928813.1 CDS pflC NC_012759.1 4033950 4034828 D MG1655 equivalent: b3952; pyruvate formate lyase II activase 4033950..4034828 Escherichia coli BW2952 7954910 YP_002928814.1 CDS frwD NC_012759.1 4034830 4035171 D FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; putative fructose-like phosphotransferase EIIB subunit 3 4034830..4035171 Escherichia coli BW2952 7955849 YP_002928815.1 CDS yijO NC_012759.1 4035158 4036009 R MG1655 equivalent: b3954; putative DNA-binding transcriptional regulator complement(4035158..4036009) Escherichia coli BW2952 7954855 YP_002928816.1 CDS yijP NC_012759.1 4036224 4037957 R MG1655 equivalent: b3955; hypothetical protein complement(4036224..4037957) Escherichia coli BW2952 7954785 YP_002928817.1 CDS ppc NC_012759.1 4038139 4040790 R catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase complement(4038139..4040790) Escherichia coli BW2952 7952692 YP_002928818.1 CDS argE NC_012759.1 4041388 4042539 R catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase complement(4041388..4042539) Escherichia coli BW2952 7954529 YP_002928819.1 CDS argC NC_012759.1 4042693 4043697 D catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 4042693..4043697 Escherichia coli BW2952 7952406 YP_002928820.1 CDS argB NC_012759.1 4043705 4044481 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 4043705..4044481 Escherichia coli BW2952 7954340 YP_002928821.1 CDS argH NC_012759.1 4044542 4045915 D catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 4044542..4045915 Escherichia coli BW2952 7952405 YP_002928822.1 CDS oxyR NC_012759.1 4046182 4047099 D Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 4046182..4047099 Escherichia coli BW2952 7952098 YP_002928823.1 CDS sthA NC_012759.1 4047082 4048482 R catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase complement(4047082..4048482) Escherichia coli BW2952 7953424 YP_002928824.1 CDS fabR NC_012759.1 4048816 4049463 D negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 4048816..4049463 Escherichia coli BW2952 7955837 YP_002928825.1 CDS yijD NC_012759.1 4049463 4049822 D MG1655 equivalent: b3964; hypothetical protein 4049463..4049822 Escherichia coli BW2952 7953470 YP_002928826.1 CDS trmA NC_012759.1 4049862 4050962 R catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase complement(4049862..4050962) Escherichia coli BW2952 7952733 YP_002928827.1 CDS btuB NC_012759.1 4051331 4053175 D involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 4051331..4053175 Escherichia coli BW2952 7956199 YP_002928828.1 CDS murI NC_012759.1 4053120 4053977 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 4053120..4053977 Escherichia coli BW2952 7956274 YP_002928829.1 CDS murB NC_012759.1 4059760 4060788 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 4059760..4060788 Escherichia coli BW2952 7952111 YP_002928830.1 CDS birA NC_012759.1 4060785 4061750 D catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 4060785..4061750 Escherichia coli BW2952 7956238 YP_002928831.1 CDS coaA NC_012759.1 4061779 4062729 R catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase complement(4061779..4062729) Escherichia coli BW2952 7952563 YP_002928832.1 CDS tufB NC_012759.1 4063647 4064831 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 4063647..4064831 Escherichia coli BW2952 7952161 YP_002928833.1 CDS secE NC_012759.1 4065061 4065444 D forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 4065061..4065444 Escherichia coli BW2952 7955787 YP_002928834.1 CDS nusG NC_012759.1 4065446 4065991 D Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 4065446..4065991 Escherichia coli BW2952 7955762 YP_002928835.1 CDS rplK NC_012759.1 4066150 4066578 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 4066150..4066578 Escherichia coli BW2952 7956170 YP_002928836.1 CDS rplA NC_012759.1 4066582 4067286 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 4066582..4067286 Escherichia coli BW2952 7952339 YP_002928837.1 CDS rplJ NC_012759.1 4067699 4068196 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 4067699..4068196 Escherichia coli BW2952 7952337 YP_002928838.1 CDS rplL NC_012759.1 4068263 4068628 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 4068263..4068628 Escherichia coli BW2952 7952338 YP_002928839.1 CDS rpoB NC_012759.1 4068948 4072976 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 4068948..4072976 Escherichia coli BW2952 7952368 YP_002928840.1 CDS rpoC NC_012759.1 4073053 4077276 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 4073053..4077276 Escherichia coli BW2952 7955985 YP_002928841.1 CDS yjaZ NC_012759.1 4077489 4078028 D MG1655 equivalent: b3989; heat shock protein 4077489..4078028 Escherichia coli BW2952 7955984 YP_002928842.1 CDS thiH NC_012759.1 4078438 4079571 R in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH complement(4078438..4079571) Escherichia coli BW2952 7953893 YP_002928843.1 CDS thiG NC_012759.1 4079568 4080338 R functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase complement(4079568..4080338) Escherichia coli BW2952 7956124 YP_002928844.1 CDS thiS NC_012759.1 4080340 4080540 R with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS complement(4080340..4080540) Escherichia coli BW2952 7956125 YP_002928845.1 CDS thiF NC_012759.1 4080524 4081279 R MG1655 equivalent: b3992; thiamin (thiazole moiety) biosynthesis protein complement(4080524..4081279) Escherichia coli BW2952 7956098 YP_002928846.1 CDS thiE NC_012759.1 4081272 4081907 R catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase complement(4081272..4081907) Escherichia coli BW2952 7956123 YP_002928847.1 CDS thiC NC_012759.1 4081907 4083802 R required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC complement(4081907..4083802) Escherichia coli BW2952 7956128 YP_002928848.1 CDS rsd NC_012759.1 4084035 4084511 R binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor complement(4084035..4084511) Escherichia coli BW2952 7956122 YP_002928849.1 CDS nudC NC_012759.1 4084606 4085379 D can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 4084606..4085379 Escherichia coli BW2952 7956067 YP_002928850.1 CDS hemE NC_012759.1 4085419 4086483 D catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 4085419..4086483 Escherichia coli BW2952 7954354 YP_002928851.1 CDS nfi NC_012759.1 4086493 4087164 D Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 4086493..4087164 Escherichia coli BW2952 7956267 YP_002928852.1 CDS yjaG NC_012759.1 4087207 4087797 D MG1655 equivalent: b3999; hypothetical protein 4087207..4087797 Escherichia coli BW2952 7953520 YP_002928853.1 CDS hupA NC_012759.1 4087984 4088256 D histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 4087984..4088256 Escherichia coli BW2952 7953050 YP_002928854.1 CDS yjaH NC_012759.1 4088269 4088964 D MG1655 equivalent: b4001; hypothetical protein 4088269..4088964 Escherichia coli BW2952 7953926 YP_002928855.1 CDS zraP NC_012759.1 4088966 4089391 R MG1655 equivalent: b4002; zinc resistance protein complement(4088966..4089391) Escherichia coli BW2952 7953051 YP_002928856.1 CDS zraS NC_012759.1 4089629 4091026 D MG1655 equivalent: b4003; sensor protein ZraS 4089629..4091026 Escherichia coli BW2952 7956290 YP_002928857.1 CDS zraR NC_012759.1 4091023 4092348 D DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR 4091023..4092348 Escherichia coli BW2952 7956026 YP_002928858.1 CDS purD NC_012759.1 4092345 4093634 R catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase complement(4092345..4093634) Escherichia coli BW2952 7953674 YP_002928859.1 CDS purH NC_012759.1 4093646 4095235 R involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase complement(4093646..4095235) Escherichia coli BW2952 7954553 YP_002928860.1 CDS yjaA NC_012759.1 4100937 4101320 D MG1655 equivalent: b4011; hypothetical protein 4100937..4101320 Escherichia coli BW2952 7952114 YP_002928861.1 CDS yjaB NC_012759.1 4101383 4101826 R MG1655 equivalent: b4012; hypothetical protein complement(4101383..4101826) Escherichia coli BW2952 7953052 YP_002928862.1 CDS metA NC_012759.1 4101983 4102912 D catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 4101983..4102912 Escherichia coli BW2952 7954601 YP_002928863.1 CDS aceB NC_012759.1 4103181 4104782 D Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 4103181..4104782 Escherichia coli BW2952 7953920 YP_002928864.1 CDS aceA NC_012759.1 4104812 4106116 D MG1655 equivalent: b4015; isocitrate lyase 4104812..4106116 Escherichia coli BW2952 7954200 YP_002928865.1 CDS aceK NC_012759.1 4106299 4108035 D catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase protein 4106299..4108035 Escherichia coli BW2952 7954052 YP_002928866.1 CDS arpA NC_012759.1 4108004 4110190 R MG1655 equivalent: b4017; ankyrin complement(4108004..4110190) Escherichia coli BW2952 7954051 YP_002928867.1 CDS iclR NC_012759.1 4110507 4111331 R regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; IclR family transcriptional regulator complement(4110507..4111331) Escherichia coli BW2952 7952480 YP_002928868.1 CDS metH NC_012759.1 4111531 4115214 D one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 4111531..4115214 Escherichia coli BW2952 7953458 YP_002928869.1 CDS yjbB NC_012759.1 4115434 4117065 D MG1655 equivalent: b4020; putative transporter 4115434..4117065 Escherichia coli BW2952 7953918 YP_002928870.1 CDS pepE NC_012759.1 4117156 4117845 R alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E complement(4117156..4117845) Escherichia coli BW2952 7955714 YP_002928871.1 CDS rluF NC_012759.1 4118057 4118929 D catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 4118057..4118929 Escherichia coli BW2952 7952215 YP_002928872.1 CDS pagB NC_012759.1 4119062 4119334 R MG1655 equivalent: b4023; hypothetical protein complement(4119062..4119334) Escherichia coli BW2952 7952248 YP_002928873.1 CDS lysC NC_012759.1 4119587 4120936 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase III complement(4119587..4120936) Escherichia coli BW2952 7952894 YP_002928874.1 CDS pgi NC_012759.1 4121461 4123110 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 4121461..4123110 Escherichia coli BW2952 7952516 YP_002928875.1 CDS yjbE NC_012759.1 4123609 4123851 D MG1655 equivalent: b4026; hypothetical protein 4123609..4123851 Escherichia coli BW2952 7953811 YP_002928876.1 CDS yjbF NC_012759.1 4123965 4124603 D MG1655 equivalent: b4027; putative lipoprotein 4123965..4124603 Escherichia coli BW2952 7955519 YP_002928877.1 CDS yjbG NC_012759.1 4124600 4125337 D MG1655 equivalent: b4028; hypothetical protein 4124600..4125337 Escherichia coli BW2952 7955118 YP_002928878.1 CDS yjbH NC_012759.1 4125337 4127433 D MG1655 equivalent: b4029; putative porin 4125337..4127433 Escherichia coli BW2952 7953053 YP_002928879.1 CDS yjbT NC_012759.1 4127480 4127758 R MG1655 equivalent: b4620; hypothetical protein complement(4127480..4127758) Escherichia coli BW2952 7955327 YP_002928880.1 CDS psiE NC_012759.1 4128028 4128438 D MG1655 equivalent: b4030; phosphate-starvation-inducible protein PsiE 4128028..4128438 Escherichia coli BW2952 7953985 YP_002928881.1 CDS xylE NC_012759.1 4128482 4129957 R xylose/proton symporter; member of the major facilitator superfamily (MFS) of transporter; D-xylose transporter XylE complement(4128482..4129957) Escherichia coli BW2952 7955313 YP_002928882.1 CDS malG NC_012759.1 4130329 4131300 R with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease complement(4130329..4131300) Escherichia coli BW2952 7953508 YP_002928883.1 CDS BWG_3689 NC_012759.1 4131538 4132128 R Repressor protein CI complement(4131538..4132128) Escherichia coli BW2952 7956299 YP_002928884.1 CDS BWG_3690 NC_012759.1 4132527 4133786 D Transposase 4132527..4133786 Escherichia coli BW2952 7955940 YP_002928885.1 CDS BWG_3691 NC_012759.1 4133862 4134518 D Transposase 4133862..4134518 Escherichia coli BW2952 7956181 YP_002928886.1 CDS BWG_3692 NC_012759.1 4135063 4135245 R hypothetical protein complement(4135063..4135245) Escherichia coli BW2952 7956182 YP_002928887.1 CDS BWG_3693 NC_012759.1 4135356 4135469 R Xis complement(4135356..4135469) Escherichia coli BW2952 7953961 YP_002928888.1 CDS BWG_3694 NC_012759.1 4135699 4136379 R Exonuclease complement(4135699..4136379) Escherichia coli BW2952 7956280 YP_002928889.1 CDS BWG_3695 NC_012759.1 4136376 4137161 R Recombination protein bet complement(4136376..4137161) Escherichia coli BW2952 7953538 YP_002928890.1 CDS BWG_3696 NC_012759.1 4137167 4137463 R Host-nuclease inhibitor protein gam complement(4137167..4137463) Escherichia coli BW2952 7955917 YP_002928891.1 CDS BWG_3697 NC_012759.1 4137538 4137681 R Protein kil complement(4137538..4137681) Escherichia coli BW2952 7953922 YP_002928892.1 CDS BWG_3698 NC_012759.1 4138158 4138919 R Aminoglucoside phosphotransferase derived originally from Tn903 complement(4138158..4138919) Escherichia coli BW2952 7955800 YP_002928893.1 CDS BWG_3699 NC_012759.1 4139137 4139505 R Lambda prophage-derived protein ea10 complement(4139137..4139505) Escherichia coli BW2952 7952467 YP_002928894.1 CDS BWG_3700 NC_012759.1 4139688 4139810 R Lambda ant-restriction protein complement(4139688..4139810) Escherichia coli BW2952 7954114 YP_002928895.1 CDS BWG_3701 NC_012759.1 4140638 4140961 R Lambda genome from map unit 74 backward to map unit 67 complement(4140638..4140961) Escherichia coli BW2952 7954111 YP_002928896.1 CDS BWG_3702 NC_012759.1 4141876 4142715 R Protein rexA complement(4141876..4142715) Escherichia coli BW2952 7954112 YP_002928897.1 CDS BWG_3703 NC_012759.1 4142828 4143541 R Repressor protein CI complement(4142828..4143541) Escherichia coli BW2952 7955807 YP_002928898.1 CDS BWG_3704 NC_012759.1 4143642 4143842 D Regulatory protein cro 4143642..4143842 Escherichia coli BW2952 7955941 YP_002928899.1 CDS BWG_3705 NC_012759.1 4144117 4144254 D Phage regulatory protein 4144117..4144254 Escherichia coli BW2952 7955929 YP_002928900.1 CDS BWG_3706 NC_012759.1 4144287 4145186 D Replication protein O 4144287..4145186 Escherichia coli BW2952 7954503 YP_002928901.1 CDS BWG_3707 NC_012759.1 4145183 4145884 D Replication protein P 4145183..4145884 Escherichia coli BW2952 7955937 YP_002928902.1 CDS BWG_3708 NC_012759.1 4146245 4146685 D Protein ninB 4146245..4146685 Escherichia coli BW2952 7955938 YP_002928903.1 CDS BWG_3709 NC_012759.1 4146664 4147554 D Nin-like protein 4146664..4147554 Escherichia coli BW2952 7955801 YP_002928904.1 CDS BWG_3710 NC_012759.1 4148447 4148644 D Protein ninG 4148447..4148644 Escherichia coli BW2952 7954386 YP_002928905.1 CDS BWG_3711 NC_012759.1 4148641 4148847 D Protein ninH 4148641..4148847 Escherichia coli BW2952 7955802 YP_002928906.1 CDS BWG_3712 NC_012759.1 4148825 4149490 D Serine/threonine-protein phosphatase 4148825..4149490 Escherichia coli BW2952 7955803 YP_002928907.1 CDS BWG_3713 NC_012759.1 4149487 4150110 D Antitermination protein Q 4149487..4150110 Escherichia coli BW2952 7956033 YP_002928908.1 CDS BWG_3714 NC_012759.1 4150787 4151110 D Includes: Lysis protein S; Lysis inhibitor; Holin (gpS protein) 4150787..4151110 Escherichia coli BW2952 7952485 YP_002928909.1 CDS BWG_3715 NC_012759.1 4151094 4151570 D lysozyme 4151094..4151570 Escherichia coli BW2952 7953915 YP_002928910.1 CDS rzpD NC_012759.1 4151567 4152028 D MG1655 equivalent: unique; DLP12 prophage; putative murein endopeptidase 4151567..4152028 Escherichia coli BW2952 7954187 YP_002928911.1 CDS rzoD NC_012759.1 4151787 4151969 D MG1655 equivalent: unique; DLP12 prophage; putative lipoprotein 4151787..4151969 Escherichia coli BW2952 7956293 YP_002928912.1 CDS borD NC_012759.1 4152060 4152353 R MG1655 equivalent: unique; DLP12 prophage; putative lipoprotein complement(4152060..4152353) Escherichia coli BW2952 7956294 YP_002928913.1 CDS ybcV NC_012759.1 4152643 4153053 R MG1655 equivalent: unique; DLP12 prophage protein complement(4152643..4153053) Escherichia coli BW2952 7956291 YP_002928914.1 CDS ybcW NC_012759.1 4153339 4153545 D MG1655 equivalent: unique; DLP12 prophage protein 4153339..4153545 Escherichia coli BW2952 7956292 YP_002928915.1 CDS nohB NC_012759.1 4154293 4154838 D MG1655 equivalent: unique; DLP12 prophage; DNA packaging protein 4154293..4154838 Escherichia coli BW2952 7956295 YP_002928916.1 CDS BWG_3722 NC_012759.1 4156735 4156941 D Lambda prophage-derived head-to-tail joining protein W 4156735..4156941 Escherichia coli BW2952 7956296 YP_002928917.1 CDS BWG_3723 NC_012759.1 4156938 4158539 D Contains: Protein B*; Portal protein B (GpB) (Minor capsid protein B) 4156938..4158539 Escherichia coli BW2952 7954113 YP_002928918.1 CDS BWG_3724 NC_012759.1 4158520 4159839 D Contains: Capsid assembly protein NU3; Minor capsid protein C (GPC) 4158520..4159839 Escherichia coli BW2952 7954571 YP_002928919.1 CDS BWG_3725 NC_012759.1 4159849 4160181 D Head decoration protein 4159849..4160181 Escherichia coli BW2952 7954263 YP_002928920.1 CDS BWG_3726 NC_012759.1 4160243 4161262 D Major head protein 4160243..4161262 Escherichia coli BW2952 7953889 YP_002928921.1 CDS BWG_3727 NC_012759.1 4161304 4161702 D DNA packaging protein FI 4161304..4161702 Escherichia coli BW2952 7954194 YP_002928922.1 CDS BWG_3728 NC_012759.1 4161714 4162067 D Tail attachment protein 4161714..4162067 Escherichia coli BW2952 7953315 YP_002928923.1 CDS BWG_3729 NC_012759.1 4162079 4162657 D Minor tail protein Z 4162079..4162657 Escherichia coli BW2952 7956106 YP_002928924.1 CDS BWG_3730 NC_012759.1 4162654 4163049 D Minor tail protein U 4162654..4163049 Escherichia coli BW2952 7954274 YP_002928925.1 CDS BWG_3731 NC_012759.1 4163057 4163797 D Major tail protein V 4163057..4163797 Escherichia coli BW2952 7954273 YP_002928926.1 CDS BWG_3732 NC_012759.1 4163813 4164235 D Minor tail protein G 4163813..4164235 Escherichia coli BW2952 7954195 YP_002928927.1 CDS BWG_3733 NC_012759.1 4164217 4164651 D Minor tail protein T 4164217..4164651 Escherichia coli BW2952 7954269 YP_002928928.1 CDS BWG_3734 NC_012759.1 4164644 4167205 D Contains: Minor tail protein H*; Minor tail protein H 4164644..4167205 Escherichia coli BW2952 7954272 YP_002928929.1 CDS BWG_3735 NC_012759.1 4167202 4167531 D Minor tail protein M 4167202..4167531 Escherichia coli BW2952 7954270 YP_002928930.1 CDS BWG_3736 NC_012759.1 4167531 4168229 D COG4672; hypothetical protein 4167531..4168229 Escherichia coli BW2952 7954271 YP_002928931.1 CDS BWG_3737 NC_012759.1 4168235 4168978 D COG0791; Cell wall-associated hydrolases (invasion-associated proteins) 4168235..4168978 Escherichia coli BW2952 7952650 YP_002928932.1 CDS BWG_3738 NC_012759.1 4169279 4169548 D Tail assembly protein I 4169279..4169548 Escherichia coli BW2952 7952649 YP_002928933.1 CDS BWG_3739 NC_012759.1 4169609 4173007 D Host specificity protein J 4169609..4173007 Escherichia coli BW2952 7956105 YP_002928934.1 CDS BWG_3740 NC_012759.1 4173069 4173689 D Outer membrane protein lom precursor 4173069..4173689 Escherichia coli BW2952 7953921 YP_002928935.1 CDS BWG_3741 NC_012759.1 4173754 4174173 D Side tail fiber protein 4173754..4174173 Escherichia coli BW2952 7954449 YP_002928936.1 CDS lacY NC_012759.1 4174500 4175753 R lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease complement(4174500..4175753) Escherichia coli BW2952 7952213 YP_002928937.1 CDS lacZ NC_012759.1 4175805 4179047 R forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase complement(4175805..4179047) Escherichia coli BW2952 7954107 YP_002928938.1 CDS BWG_3745 NC_012759.1 4179047 4180240 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(4179047..4180240) Escherichia coli BW2952 7952548 YP_002928939.1 CDS malF NC_012759.1 4180399 4181943 R with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein complement(4180399..4181943) Escherichia coli BW2952 7952211 YP_002928940.1 CDS malE NC_012759.1 4182097 4183287 R functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein complement(4182097..4183287) Escherichia coli BW2952 7954208 YP_002928941.1 CDS malK NC_012759.1 4183652 4184767 D with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 4183652..4184767 Escherichia coli BW2952 7954209 YP_002928942.1 CDS lamB NC_012759.1 4184839 4186179 D porin involved in the transport of maltose and maltodextrins; maltoporin 4184839..4186179 Escherichia coli BW2952 7953697 YP_002928943.1 CDS malM NC_012759.1 4186422 4187342 D MG1655 equivalent: b4037; maltose regulon periplasmic protein 4186422..4187342 Escherichia coli BW2952 7954206 YP_002928944.1 CDS ubiC NC_012759.1 4189374 4189871 D catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 4189374..4189871 Escherichia coli BW2952 7954207 YP_002928945.1 CDS ubiA NC_012759.1 4189884 4190756 D catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 4189884..4190756 Escherichia coli BW2952 7952635 YP_002928946.1 CDS plsB NC_012759.1 4190911 4193334 R PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase complement(4190911..4193334) Escherichia coli BW2952 7954557 YP_002928947.1 CDS dgkA NC_012759.1 4193505 4193873 D MG1655 equivalent: b4042; diacylglycerol kinase 4193505..4193873 Escherichia coli BW2952 7953849 YP_002928948.1 CDS lexA NC_012759.1 4193983 4194591 D Represses a number of genes involved in the response to DNA damage; LexA repressor 4193983..4194591 Escherichia coli BW2952 7953245 YP_002928949.1 CDS dinF NC_012759.1 4194610 4195989 D MG1655 equivalent: b4044; DNA-damage-inducible SOS response protein 4194610..4195989 Escherichia coli BW2952 7953476 YP_002928950.1 CDS yjbJ NC_012759.1 4196105 4196314 D unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; putative stress-response protein 4196105..4196314 Escherichia coli BW2952 7953486 YP_002928951.1 CDS zur NC_012759.1 4196356 4196871 R Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor complement(4196356..4196871) Escherichia coli BW2952 7955600 YP_002928952.1 CDS yjbL NC_012759.1 4197189 4197443 D MG1655 equivalent: b4047; hypothetical protein 4197189..4197443 Escherichia coli BW2952 7953483 YP_002928953.1 CDS yjbM NC_012759.1 4197467 4198174 D MG1655 equivalent: b4048; hypothetical protein 4197467..4198174 Escherichia coli BW2952 7955520 YP_002928954.1 CDS dusA NC_012759.1 4198582 4199574 D MG1655 equivalent: b4049; tRNA-dihydrouridine synthase A 4198582..4199574 Escherichia coli BW2952 7955521 YP_002928955.1 CDS pspG NC_012759.1 4199708 4199950 D coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 4199708..4199950 Escherichia coli BW2952 7956204 YP_002928956.1 CDS qor NC_012759.1 4200116 4201099 R MG1655 equivalent: b4051; quinone oxidoreductase complement(4200116..4201099) Escherichia coli BW2952 7954504 YP_002928957.1 CDS dnaB NC_012759.1 4201182 4202597 D unwinds double stranded DNA; replicative DNA helicase 4201182..4202597 Escherichia coli BW2952 7955889 YP_002928958.1 CDS alr NC_012759.1 4202650 4203729 D converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 4202650..4203729 Escherichia coli BW2952 7955939 YP_002928959.1 CDS tyrB NC_012759.1 4203982 4205175 D catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 4203982..4205175 Escherichia coli BW2952 7952438 YP_002928960.1 CDS yjbS NC_012759.1 4205677 4205880 R MG1655 equivalent: b4621; hypothetical protein complement(4205677..4205880) Escherichia coli BW2952 7956221 YP_002928961.1 CDS aphA NC_012759.1 4206282 4206995 D Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 4206282..4206995 Escherichia coli BW2952 7953971 YP_002928962.1 CDS yjbQ NC_012759.1 4207106 4207522 D MG1655 equivalent: b4056; hypothetical protein 4207106..4207522 Escherichia coli BW2952 7952407 YP_002928963.1 CDS yjbR NC_012759.1 4207526 4207882 D MG1655 equivalent: b4057; hypothetical protein 4207526..4207882 Escherichia coli BW2952 7953054 YP_002928964.1 CDS uvrA NC_012759.1 4207917 4210739 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(4207917..4210739) Escherichia coli BW2952 7953055 YP_002928965.1 CDS ssb NC_012759.1 4210993 4211529 D binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 4210993..4211529 Escherichia coli BW2952 7952523 YP_002928966.1 CDS yjcB NC_012759.1 4211628 4211909 R MG1655 equivalent: b4060; putative inner membrane protein complement(4211628..4211909) Escherichia coli BW2952 7956046 YP_002928967.1 CDS yjcC NC_012759.1 4212339 4213925 D MG1655 equivalent: b4061; putative signal transduction protein (EAL domain containing protein) 4212339..4213925 Escherichia coli BW2952 7955016 YP_002928968.1 CDS soxS NC_012759.1 4213928 4214251 R regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS complement(4213928..4214251) Escherichia coli BW2952 7955592 YP_002928969.1 CDS soxR NC_012759.1 4214337 4214801 D MG1655 equivalent: b4063; DNA-binding transcriptional dual regulator, Fe-S center for redox-sensing 4214337..4214801 Escherichia coli BW2952 7953415 YP_002928970.1 CDS yjcD NC_012759.1 4215347 4216696 D MG1655 equivalent: b4064; putative permease 4215347..4216696 Escherichia coli BW2952 7952099 YP_002928971.1 CDS yjcE NC_012759.1 4216848 4218497 D MG1655 equivalent: b4065; putative cation/proton antiporter 4216848..4218497 Escherichia coli BW2952 7955309 YP_002928972.1 CDS actP NC_012759.1 4220122 4221771 R member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease complement(4220122..4221771) Escherichia coli BW2952 7952207 YP_002928973.1 CDS yjcH NC_012759.1 4221768 4222082 R MG1655 equivalent: b4068; acetate transport inner membrane protein complement(4221768..4222082) Escherichia coli BW2952 7952389 YP_002928974.1 CDS acs NC_012759.1 4222282 4224240 R Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase complement(4222282..4224240) Escherichia coli BW2952 7952742 YP_002928975.1 CDS nrfA NC_012759.1 4224633 4226069 D catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 4224633..4226069 Escherichia coli BW2952 7952402 YP_002928976.1 CDS nrfB NC_012759.1 4226114 4226680 D part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 4226114..4226680 Escherichia coli BW2952 7954399 YP_002928977.1 CDS nrfC NC_012759.1 4226677 4227348 D MG1655 equivalent: b4072; formate-dependent nitrite reductase, 4Fe4S subunit 4226677..4227348 Escherichia coli BW2952 7954400 YP_002928978.1 CDS nrfD NC_012759.1 4227345 4228301 D MG1655 equivalent: b4073; formate-dependent nitrite reductase, membrane subunit 4227345..4228301 Escherichia coli BW2952 7953627 YP_002928979.1 CDS nrfE NC_012759.1 4228381 4230039 D with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 4228381..4230039 Escherichia coli BW2952 7953628 YP_002928980.1 CDS nrfF NC_012759.1 4230032 4230415 D MG1655 equivalent: b4075; formate-dependent nitrite reductase complex subunit NrfF 4230032..4230415 Escherichia coli BW2952 7953899 YP_002928981.1 CDS nrfG NC_012759.1 4230412 4231008 D MG1655 equivalent: b4076; formate-dependent nitrite reductase complex subunit NrfG 4230412..4231008 Escherichia coli BW2952 7953900 YP_002928982.1 CDS gltP NC_012759.1 4231350 4232663 D carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 4231350..4232663 Escherichia coli BW2952 7953901 YP_002928983.1 CDS yjcO NC_012759.1 4233194 4233883 R MG1655 equivalent: b4078; hypothetical protein complement(4233194..4233883) Escherichia coli BW2952 7953825 YP_002928984.1 CDS fdhF NC_012759.1 4233977 4236124 R MG1655 equivalent: b4079; formate dehydrogenase-H, selenopolypeptide subunit complement(4233977..4236124) Escherichia coli BW2952 7952895 YP_002928985.1 CDS mdtP NC_012759.1 4236322 4237788 R part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; putative outer membrane efflux protein MdtP complement(4236322..4237788) Escherichia coli BW2952 7953618 YP_002928986.1 CDS mdtO NC_012759.1 4237785 4239836 R possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO complement(4237785..4239836) Escherichia coli BW2952 7955197 YP_002928987.1 CDS mdtN NC_012759.1 4239836 4240867 R with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN complement(4239836..4240867) Escherichia coli BW2952 7955174 YP_002928988.1 CDS ytcA NC_012759.1 4240886 4241161 R MG1655 equivalent: b4622; hypothetical protein complement(4240886..4241161) Escherichia coli BW2952 7955139 YP_002928989.1 CDS yjcS NC_012759.1 4241370 4243355 R MG1655 equivalent: b4083; putative alkyl sulfatase complement(4241370..4243355) Escherichia coli BW2952 7953972 YP_002928990.1 CDS alsK NC_012759.1 4243628 4244557 R MG1655 equivalent: b4084; D-allose kinase complement(4243628..4244557) Escherichia coli BW2952 7954632 YP_002928991.1 CDS alsE NC_012759.1 4244541 4245236 R MG1655 equivalent: b4085; allulose-6-phosphate 3-epimerase complement(4244541..4245236) Escherichia coli BW2952 7953222 YP_002928992.1 CDS alsC NC_012759.1 4245247 4246227 R MG1655 equivalent: b4086; D-allose transporter subunit complement(4245247..4246227) Escherichia coli BW2952 7952454 YP_002928993.1 CDS alsA NC_012759.1 4246206 4247738 R with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains; D-allose transporter ATP-binding protein complement(4246206..4247738) Escherichia coli BW2952 7953223 YP_002928994.1 CDS alsB NC_012759.1 4247865 4248800 R MG1655 equivalent: b4088; D-allose transporter subunit complement(4247865..4248800) Escherichia coli BW2952 7953670 YP_002928995.1 CDS rpiR NC_012759.1 4248859 4249749 R involved in rpiB and als operon repression; DNA-binding transcriptional repressor RpiR complement(4248859..4249749) Escherichia coli BW2952 7953224 YP_002928996.1 CDS rpiB NC_012759.1 4250108 4250557 D catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 4250108..4250557 Escherichia coli BW2952 7953459 YP_002928997.1 CDS yjdP NC_012759.1 4250626 4250955 D MG1655 equivalent: b4487; hypothetical protein 4250626..4250955 Escherichia coli BW2952 7955972 YP_002928998.1 CDS phnP NC_012759.1 4251102 4251860 R required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein complement(4251102..4251860) Escherichia coli BW2952 7953069 YP_002928999.1 CDS phnO NC_012759.1 4251862 4252296 R PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role; aminoalkylphosphonic acid N-acetyltransferase complement(4251862..4252296) Escherichia coli BW2952 7952598 YP_002929000.1 CDS phnN NC_012759.1 4252283 4252840 R MG1655 equivalent: b4094; ribose 1,5-bisphosphokinase complement(4252283..4252840) Escherichia coli BW2952 7954619 YP_002929001.1 CDS phnM NC_012759.1 4252840 4253976 R MG1655 equivalent: b4095; carbon-phosphorus lyase complex subunit complement(4252840..4253976) Escherichia coli BW2952 7955971 YP_002929002.1 CDS phnL NC_012759.1 4253973 4254653 R MG1655 equivalent: b4096; carbon-phosphorus lyase complex subunit complement(4253973..4254653) Escherichia coli BW2952 7952599 YP_002929003.1 CDS phnK NC_012759.1 4254764 4255522 R MG1655 equivalent: b4097; phosphonate C-P lyase system protein PhnK complement(4254764..4255522) Escherichia coli BW2952 7952600 YP_002929004.1 CDS phnJ NC_012759.1 4255519 4256364 R MG1655 equivalent: b4098; carbon-phosphorus lyase complex subunit complement(4255519..4256364) Escherichia coli BW2952 7952601 YP_002929005.1 CDS phnI NC_012759.1 4256357 4257421 R MG1655 equivalent: b4099; carbon-phosphorus lyase complex subunit complement(4256357..4257421) Escherichia coli BW2952 7952602 YP_002929006.1 CDS phnH NC_012759.1 4257421 4258005 R MG1655 equivalent: b4100; carbon-phosphorus lyase complex subunit complement(4257421..4258005) Escherichia coli BW2952 7952603 YP_002929007.1 CDS phnG NC_012759.1 4258002 4258454 R MG1655 equivalent: b4101; carbon-phosphorus lyase complex subunit complement(4258002..4258454) Escherichia coli BW2952 7952604 YP_002929008.1 CDS phnF NC_012759.1 4258455 4259180 R may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF complement(4258455..4259180) Escherichia coli BW2952 7952605 YP_002929009.1 CDS phnD NC_012759.1 4260094 4261110 R MG1655 equivalent: b4105; phosphonate/organophosphate ester transporter subunit complement(4260094..4261110) Escherichia coli BW2952 7954821 YP_002929010.1 CDS phnC NC_012759.1 4261135 4261923 R MG1655 equivalent: b4106; phosphonate/organophosphate ester transporter subunit complement(4261135..4261923) Escherichia coli BW2952 7954544 YP_002929011.1 CDS yjdN NC_012759.1 4262056 4262499 R MG1655 equivalent: b4107; hypothetical protein complement(4262056..4262499) Escherichia coli BW2952 7954545 YP_002929012.1 CDS yjdM NC_012759.1 4263157 4263492 R MG1655 equivalent: b4108; hypothetical protein complement(4263157..4263492) Escherichia coli BW2952 7952896 YP_002929013.1 CDS yjdA NC_012759.1 4263893 4266121 D MG1655 equivalent: b4109; hypothetical protein 4263893..4266121 Escherichia coli BW2952 7952897 YP_002929014.1 CDS yjcZ NC_012759.1 4266118 4266996 D MG1655 equivalent: b4110; hypothetical protein 4266118..4266996 Escherichia coli BW2952 7953092 YP_002929015.1 CDS proP NC_012759.1 4267260 4268762 D MG1655 equivalent: b4111; proline/glycine betaine transporter 4267260..4268762 Escherichia coli BW2952 7953056 YP_002929016.1 CDS basS NC_012759.1 4268939 4270030 R MG1655 equivalent: b4112; sensor protein BasS/PmrB complement(4268939..4270030) Escherichia coli BW2952 7955769 YP_002929017.1 CDS basR NC_012759.1 4270040 4270708 R response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR complement(4270040..4270708) Escherichia coli BW2952 7956013 YP_002929018.1 CDS eptA NC_012759.1 4270705 4272348 R with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; putative cell division protein complement(4270705..4272348) Escherichia coli BW2952 7953346 YP_002929019.1 CDS adiC NC_012759.1 4272452 4273789 R MG1655 equivalent: b4115; arginine:agmatin antiporter complement(4272452..4273789) Escherichia coli BW2952 7955144 YP_002929020.1 CDS adiY NC_012759.1 4273926 4274687 R MG1655 equivalent: b4116; DNA-binding transcriptional activator complement(4273926..4274687) Escherichia coli BW2952 7952500 YP_002929021.1 CDS adiA NC_012759.1 4275012 4277282 R MG1655 equivalent: b4117; biodegradative arginine decarboxylase complement(4275012..4277282) Escherichia coli BW2952 7953372 YP_002929022.1 CDS melR NC_012759.1 4277478 4278386 R MG1655 equivalent: b4118; DNA-binding transcriptional regulator MelR complement(4277478..4278386) Escherichia coli BW2952 7952577 YP_002929023.1 CDS melA NC_012759.1 4278669 4280024 D MG1655 equivalent: b4119; alpha-galactosidase, NAD(P)-binding 4278669..4280024 Escherichia coli BW2952 7953416 YP_002929024.1 CDS melB NC_012759.1 4280139 4281548 D MG1655 equivalent: b4120; melibiose:sodium symporter 4280139..4281548 Escherichia coli BW2952 7952457 YP_002929025.1 CDS yjdF NC_012759.1 4281687 4282316 R MG1655 equivalent: b4121; hypothetical protein complement(4281687..4282316) Escherichia coli BW2952 7954221 YP_002929026.1 CDS fumB NC_012759.1 4282438 4284084 R MG1655 equivalent: b4122; anaerobic class I fumarate hydratase (fumarase B) complement(4282438..4284084) Escherichia coli BW2952 7952693 YP_002929027.1 CDS dcuB NC_012759.1 4284162 4285502 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter complement(4284162..4285502) Escherichia coli BW2952 7952477 YP_002929028.1 CDS dcuR NC_012759.1 4286073 4286792 R response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DNA-binding transcriptional activator DcuR complement(4286073..4286792) Escherichia coli BW2952 7952586 YP_002929029.1 CDS dcuS NC_012759.1 4286789 4288420 R C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS complement(4286789..4288420) Escherichia coli BW2952 7953351 YP_002929030.1 CDS yjdI NC_012759.1 4288601 4288831 D MG1655 equivalent: b4126; hypothetical protein 4288601..4288831 Escherichia coli BW2952 7956018 YP_002929031.1 CDS yjdJ NC_012759.1 4288843 4289115 D MG1655 equivalent: b4127; putative acyltransferase with acyl-CoA N-acyltransferase domain 4288843..4289115 Escherichia coli BW2952 7953057 YP_002929032.1 CDS yjdK NC_012759.1 4289342 4289638 D MG1655 equivalent: b4128; hypothetical protein 4289342..4289638 Escherichia coli BW2952 7954622 YP_002929033.1 CDS yjdO NC_012759.1 4289666 4289839 D MG1655 equivalent: b4559; hypothetical protein 4289666..4289839 Escherichia coli BW2952 7955522 YP_002929034.1 CDS lysU NC_012759.1 4289958 4291475 R class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(4289958..4291475) Escherichia coli BW2952 7955539 YP_002929035.1 CDS yjdL NC_012759.1 4291712 4293169 R MG1655 equivalent: b4130; putative transporter complement(4291712..4293169) Escherichia coli BW2952 7954184 YP_002929036.1 CDS cadA NC_012759.1 4293228 4295375 R MG1655 equivalent: b4131; lysine decarboxylase 1 complement(4293228..4295375) Escherichia coli BW2952 7955674 YP_002929037.1 CDS cadB NC_012759.1 4295455 4296789 R antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter complement(4295455..4296789) Escherichia coli BW2952 7954180 YP_002929038.1 CDS cadC NC_012759.1 4297154 4298692 R regulates the cadBA operon; DNA-binding transcriptional activator CadC complement(4297154..4298692) Escherichia coli BW2952 7955128 YP_002929039.1 CDS yjdC NC_012759.1 4299491 4300066 R MG1655 equivalent: b4135; putative transcriptional regulator complement(4299491..4300066) Escherichia coli BW2952 7952074 YP_002929040.1 CDS dipZ NC_012759.1 4300103 4301800 R two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein complement(4300103..4301800) Escherichia coli BW2952 7955631 YP_002929041.1 CDS cutA NC_012759.1 4301776 4302114 R copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA complement(4301776..4302114) Escherichia coli BW2952 7953746 YP_002929042.1 CDS dcuA NC_012759.1 4302230 4303531 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter complement(4302230..4303531) Escherichia coli BW2952 7953095 YP_002929043.1 CDS aspA NC_012759.1 4303649 4305085 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(4303649..4305085) Escherichia coli BW2952 7952587 YP_002929044.1 CDS fxsA NC_012759.1 4305422 4305898 D F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 4305422..4305898 Escherichia coli BW2952 7952512 YP_002929045.1 CDS yjeH NC_012759.1 4305914 4307170 R uncharacterized member of the APC superfamily of amino acid transporters; unknown function; inner membrane protein YjeH complement(4305914..4307170) Escherichia coli BW2952 7953997 YP_002929046.1 CDS groES NC_012759.1 4307446 4307739 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 4307446..4307739 Escherichia coli BW2952 7955675 YP_002929047.1 CDS groEL NC_012759.1 4307783 4309429 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 4307783..4309429 Escherichia coli BW2952 7953140 YP_002929048.1 CDS yjeI NC_012759.1 4309567 4309920 D MG1655 equivalent: b4144; hypothetical protein 4309567..4309920 Escherichia coli BW2952 7953141 YP_002929049.1 CDS yjeJ NC_012759.1 4310123 4310992 R MG1655 equivalent: b4145; hypothetical protein complement(4310123..4310992) Escherichia coli BW2952 7953058 YP_002929050.1 CDS yjeK NC_012759.1 4311387 4312415 R MG1655 equivalent: b4146; putative lysine aminomutase complement(4311387..4312415) Escherichia coli BW2952 7955426 YP_002929051.1 CDS efp NC_012759.1 4312457 4313023 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 4312457..4313023 Escherichia coli BW2952 7955127 YP_002929052.1 CDS ecnA NC_012759.1 4313075 4313200 D acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex; entericidin A 4313075..4313200 Escherichia coli BW2952 7953514 YP_002929053.1 CDS ecnB NC_012759.1 4313311 4313457 D MG1655 equivalent: b4411; entericidin B membrane lipoprotein 4313311..4313457 Escherichia coli BW2952 7953525 YP_002929054.1 CDS sugE NC_012759.1 4313633 4313950 D member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; quaternary ammonium compound-resistance protein SugE 4313633..4313950 Escherichia coli BW2952 7953526 YP_002929055.1 CDS blc NC_012759.1 4313947 4314480 R lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc complement(4313947..4314480) Escherichia coli BW2952 7954307 YP_002929056.1 CDS ampC NC_012759.1 4314569 4315702 R MG1655 equivalent: b4150; beta-lactamase complement(4314569..4315702) Escherichia coli BW2952 7954440 YP_002929057.1 CDS frdD NC_012759.1 4315765 4316124 R in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D complement(4315765..4316124) Escherichia coli BW2952 7952553 YP_002929058.1 CDS frdC NC_012759.1 4316135 4316530 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C complement(4316135..4316530) Escherichia coli BW2952 7953646 YP_002929059.1 CDS frdB NC_012759.1 4316541 4317275 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit complement(4316541..4317275) Escherichia coli BW2952 7953647 YP_002929060.1 CDS frdA NC_012759.1 4317268 4319076 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(4317268..4319076) Escherichia coli BW2952 7953645 YP_002929061.1 CDS poxA NC_012759.1 4319401 4320378 D lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 4319401..4320378 Escherichia coli BW2952 7953644 YP_002929062.1 CDS yjeM NC_012759.1 4320597 4322099 D MG1655 equivalent: b4156; putative transporter 4320597..4322099 Escherichia coli BW2952 7955130 YP_002929063.1 CDS yjeN NC_012759.1 4322151 4322465 D MG1655 equivalent: b4157; hypothetical protein 4322151..4322465 Escherichia coli BW2952 7955715 YP_002929064.1 CDS yjeO NC_012759.1 4322462 4322776 D MG1655 equivalent: b4158; hypothetical protein 4322462..4322776 Escherichia coli BW2952 7955523 YP_002929065.1 CDS yjeP NC_012759.1 4322805 4326128 R MG1655 equivalent: b4159; hypothetical protein complement(4322805..4326128) Escherichia coli BW2952 7952734 YP_002929066.1 CDS psd NC_012759.1 4326150 4327118 R catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase complement(4326150..4327118) Escherichia coli BW2952 7955137 YP_002929067.1 CDS rsgA NC_012759.1 4327215 4328267 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(4327215..4328267) Escherichia coli BW2952 7954525 YP_002929068.1 CDS orn NC_012759.1 4328362 4328907 D 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 4328362..4328907 Escherichia coli BW2952 7955979 YP_002929069.1 CDS yjeS NC_012759.1 4329686 4330825 R MG1655 equivalent: b4166; putative Fe-S electron transport protein complement(4329686..4330825) Escherichia coli BW2952 7952165 YP_002929070.1 CDS yjeF NC_012759.1 4330824 4332371 D MG1655 equivalent: b4167; hypothetical protein 4330824..4332371 Escherichia coli BW2952 7954871 YP_002929071.1 CDS yjeE NC_012759.1 4332343 4332804 D possibly involved in cell wall synthesis; putative ATPase 4332343..4332804 Escherichia coli BW2952 7954675 YP_002929072.1 CDS amiB NC_012759.1 4332823 4334160 D MG1655 equivalent: b4169; N-acetylmuramoyl-l-alanine amidase II 4332823..4334160 Escherichia coli BW2952 7952527 YP_002929073.1 CDS mutL NC_012759.1 4334170 4336017 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 4334170..4336017 Escherichia coli BW2952 7954345 YP_002929074.1 CDS miaA NC_012759.1 4336010 4336960 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 4336010..4336960 Escherichia coli BW2952 7954256 YP_002929075.1 CDS hfq NC_012759.1 4337046 4337354 D Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 4337046..4337354 Escherichia coli BW2952 7953233 YP_002929076.1 CDS hflX NC_012759.1 4337430 4338710 D involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; putative GTPase HflX 4337430..4338710 Escherichia coli BW2952 7953907 YP_002929077.1 CDS hflK NC_012759.1 4338796 4340055 D with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 4338796..4340055 Escherichia coli BW2952 7954940 YP_002929078.1 CDS hflC NC_012759.1 4340058 4341062 D with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 4340058..4341062 Escherichia coli BW2952 7954275 YP_002929079.1 CDS yjeT NC_012759.1 4341144 4341341 D MG1655 equivalent: b4176; hypothetical protein 4341144..4341341 Escherichia coli BW2952 7954276 YP_002929080.1 CDS purA NC_012759.1 4341445 4342743 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 4341445..4342743 Escherichia coli BW2952 7952735 YP_002929081.1 CDS nsrR NC_012759.1 4342948 4343373 D negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 4342948..4343373 Escherichia coli BW2952 7952425 YP_002929082.1 CDS rnr NC_012759.1 4343412 4345853 D 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 4343412..4345853 Escherichia coli BW2952 7954818 YP_002929083.1 CDS rlmB NC_012759.1 4346033 4346764 D Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 4346033..4346764 Escherichia coli BW2952 7953549 YP_002929084.1 CDS yjfI NC_012759.1 4346891 4347292 D MG1655 equivalent: b4181; hypothetical protein 4346891..4347292 Escherichia coli BW2952 7952241 YP_002929085.1 CDS yjfJ NC_012759.1 4347311 4348009 D MG1655 equivalent: b4182; putative transcriptional regulator effector protein 4347311..4348009 Escherichia coli BW2952 7953059 YP_002929086.1 CDS yjfK NC_012759.1 4348060 4348719 D MG1655 equivalent: b4183; hypothetical protein 4348060..4348719 Escherichia coli BW2952 7955642 YP_002929087.1 CDS yjfL NC_012759.1 4348737 4349135 D MG1655 equivalent: b4184; hypothetical protein 4348737..4349135 Escherichia coli BW2952 7953060 YP_002929088.1 CDS yjfM NC_012759.1 4349145 4349783 D MG1655 equivalent: b4185; hypothetical protein 4349145..4349783 Escherichia coli BW2952 7952736 YP_002929089.1 CDS yjfC NC_012759.1 4349786 4350949 D MG1655 equivalent: b4186; putative synthetase/amidase 4349786..4350949 Escherichia coli BW2952 7953061 YP_002929090.1 CDS aidB NC_012759.1 4351033 4352658 D catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 4351033..4352658 Escherichia coli BW2952 7955617 YP_002929091.1 CDS yjfN NC_012759.1 4352775 4353050 R MG1655 equivalent: b4188; hypothetical protein complement(4352775..4353050) Escherichia coli BW2952 7954057 YP_002929092.1 CDS yjfO NC_012759.1 4353199 4353528 R in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; putative biofilm stress and motility protein A complement(4353199..4353528) Escherichia coli BW2952 7955427 YP_002929093.1 CDS yjfP NC_012759.1 4353710 4354459 D YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 4353710..4354459 Escherichia coli BW2952 7952898 YP_002929094.1 CDS ulaR NC_012759.1 4354456 4355211 R negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR complement(4354456..4355211) Escherichia coli BW2952 7954975 YP_002929095.1 CDS ulaG NC_012759.1 4355319 4356383 R MG1655 equivalent: b4192; putative L-ascorbate 6-phosphate lactonase complement(4355319..4356383) Escherichia coli BW2952 7953417 YP_002929096.1 CDS ulaA NC_012759.1 4356738 4358135 D membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 4356738..4358135 Escherichia coli BW2952 7955099 YP_002929097.1 CDS ulaB NC_012759.1 4358151 4358456 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIB 4358151..4358456 Escherichia coli BW2952 7954119 YP_002929098.1 CDS ulaC NC_012759.1 4358466 4358930 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIA 4358466..4358930 Escherichia coli BW2952 7954118 YP_002929099.1 CDS ulaD NC_012759.1 4358944 4359594 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 4358944..4359594 Escherichia coli BW2952 7954117 YP_002929100.1 CDS ulaE NC_012759.1 4359604 4360458 D UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 4359604..4360458 Escherichia coli BW2952 7952310 YP_002929101.1 CDS sgaE NC_012759.1 4360458 4361144 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4360458..4361144 Escherichia coli BW2952 7954177 YP_002929102.1 CDS yjfY NC_012759.1 4361274 4361549 R MG1655 equivalent: b4199; hypothetical protein complement(4361274..4361549) Escherichia coli BW2952 7954168 YP_002929103.1 CDS rpsF NC_012759.1 4361876 4362271 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 4361876..4362271 Escherichia coli BW2952 7955428 YP_002929104.1 CDS priB NC_012759.1 4362278 4362592 D binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 4362278..4362592 Escherichia coli BW2952 7952290 YP_002929105.1 CDS rpsR NC_012759.1 4362597 4362824 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 4362597..4362824 Escherichia coli BW2952 7955764 YP_002929106.1 CDS rplI NC_012759.1 4362866 4363315 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 4362866..4363315 Escherichia coli BW2952 7952281 YP_002929107.1 CDS yjfZ NC_012759.1 4363386 4364180 R MG1655 equivalent: b4204; hypothetical protein complement(4363386..4364180) Escherichia coli BW2952 7952369 YP_002929108.1 CDS ytfB NC_012759.1 4364837 4365475 R MG1655 equivalent: b4206; putative cell envelope opacity-associated protein complement(4364837..4365475) Escherichia coli BW2952 7955429 YP_002929109.1 CDS fklB NC_012759.1 4365693 4366313 D FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 4365693..4366313 Escherichia coli BW2952 7954686 YP_002929110.1 CDS cycA NC_012759.1 4366622 4368034 D involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 4366622..4368034 Escherichia coli BW2952 7953581 YP_002929111.1 CDS ytfE NC_012759.1 4368079 4368741 R Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein complement(4368079..4368741) Escherichia coli BW2952 7953214 YP_002929112.1 CDS ytfF NC_012759.1 4368849 4369823 R MG1655 equivalent: b4210; putative inner membrane protein complement(4368849..4369823) Escherichia coli BW2952 7955563 YP_002929113.1 CDS ytfG NC_012759.1 4369922 4370782 R MG1655 equivalent: b4211; NAD(P)H:quinone oxidoreductase complement(4369922..4370782) Escherichia coli BW2952 7955017 YP_002929114.1 CDS ytfH NC_012759.1 4370871 4371251 D MG1655 equivalent: b4212; putative transcriptional regulator 4370871..4371251 Escherichia coli BW2952 7954351 YP_002929115.1 CDS cpdB NC_012759.1 4371380 4373323 R periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein complement(4371380..4373323) Escherichia coli BW2952 7955640 YP_002929116.1 CDS cysQ NC_012759.1 4373513 4374253 D catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 4373513..4374253 Escherichia coli BW2952 7952240 YP_002929117.1 CDS ytfI NC_012759.1 4374465 4375403 D MG1655 equivalent: b4215; hypothetical protein 4374465..4375403 Escherichia coli BW2952 7954467 YP_002929118.1 CDS ytfJ NC_012759.1 4375466 4376020 R MG1655 equivalent: b4216; putative transcriptional regulator complement(4375466..4376020) Escherichia coli BW2952 7955524 YP_002929119.1 CDS ytfK NC_012759.1 4376345 4376551 D MG1655 equivalent: b4217; hypothetical protein 4376345..4376551 Escherichia coli BW2952 7955632 YP_002929120.1 CDS ytfL NC_012759.1 4376630 4377973 R MG1655 equivalent: b4218; putative inner membrane protein complement(4376630..4377973) Escherichia coli BW2952 7953062 YP_002929121.1 CDS msrA NC_012759.1 4378296 4378934 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A complement(4378296..4378934) Escherichia coli BW2952 7955018 YP_002929122.1 CDS ytfM NC_012759.1 4379140 4380873 D MG1655 equivalent: b4220; putative outer membrane protein and surface antigen 4379140..4380873 Escherichia coli BW2952 7954245 YP_002929123.1 CDS ytfN NC_012759.1 4380870 4384649 D MG1655 equivalent: b4221; hypothetical protein 4380870..4384649 Escherichia coli BW2952 7955216 YP_002929124.1 CDS ytfP NC_012759.1 4384652 4384993 D MG1655 equivalent: b4222; hypothetical protein 4384652..4384993 Escherichia coli BW2952 7953063 YP_002929125.1 CDS chpS NC_012759.1 4385205 4385456 D part of the toxin-antitoxin ChpB-ChpS system; antitoxin ChpS 4385205..4385456 Escherichia coli BW2952 7953064 YP_002929126.1 CDS chpB NC_012759.1 4385450 4385800 D toxin of the ChpB-ChpS toxin-antitoxin system; toxin ChpB 4385450..4385800 Escherichia coli BW2952 7952487 YP_002929127.1 CDS ppa NC_012759.1 4385880 4386410 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(4385880..4386410) Escherichia coli BW2952 7956161 YP_002929128.1 CDS ytfQ NC_012759.1 4386720 4387676 D MG1655 equivalent: b4227; putative sugar transporter subunit: periplasmic-binding component of ABC superfamily 4386720..4387676 Escherichia coli BW2952 7953999 YP_002929129.1 CDS ytfR NC_012759.1 4387816 4389318 D MG1655 equivalent: b4485; putative sugar transporter subunit: ATP-binding component of ABC superfamily 4387816..4389318 Escherichia coli BW2952 7955611 YP_002929130.1 CDS ytfT NC_012759.1 4389329 4390354 D MG1655 equivalent: b4230; putative sugar transporter subunit: membrane component of ABC superfamily 4389329..4390354 Escherichia coli BW2952 7955612 YP_002929131.1 CDS yjfF NC_012759.1 4390341 4391336 D membrane component of a putative sugar ABC transporter system; inner membrane ABC transporter permease YjfF 4390341..4391336 Escherichia coli BW2952 7955614 YP_002929132.1 CDS fbp NC_012759.1 4391369 4392367 R catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase complement(4391369..4392367) Escherichia coli BW2952 7955608 YP_002929133.1 CDS mpl NC_012759.1 4392543 4393916 D MG1655 equivalent: b4233; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 4392543..4393916 Escherichia coli BW2952 7953634 YP_002929134.1 CDS yjgA NC_012759.1 4394072 4394623 R MG1655 equivalent: b4234; hypothetical protein complement(4394072..4394623) Escherichia coli BW2952 7956242 YP_002929135.1 CDS pmbA NC_012759.1 4394717 4396069 D protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 4394717..4396069 Escherichia coli BW2952 7952899 YP_002929136.1 CDS nrdG NC_012759.1 4396658 4397122 R activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein complement(4396658..4397122) Escherichia coli BW2952 7955288 YP_002929137.1 CDS nrdD NC_012759.1 4397280 4399418 R Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase complement(4397280..4399418) Escherichia coli BW2952 7952479 YP_002929138.1 CDS treC NC_012759.1 4399812 4401467 R MG1655 equivalent: b4239; trehalose-6-phosphate hydrolase complement(4399812..4401467) Escherichia coli BW2952 7952478 YP_002929139.1 CDS treB NC_012759.1 4401517 4402938 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunit IIBC complement(4401517..4402938) Escherichia coli BW2952 7956187 YP_002929140.1 CDS treR NC_012759.1 4403057 4404004 R regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor complement(4403057..4404004) Escherichia coli BW2952 7953749 YP_002929141.1 CDS mgtA NC_012759.1 4404383 4407079 D P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 4404383..4407079 Escherichia coli BW2952 7953460 YP_002929142.1 CDS yjgF NC_012759.1 4407285 4407671 R MG1655 equivalent: b4243; ketoacid-binding protein complement(4407285..4407671) Escherichia coli BW2952 7954191 YP_002929143.1 CDS pyrI NC_012759.1 4407744 4408205 R involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase regulatory subunit complement(4407744..4408205) Escherichia coli BW2952 7954058 YP_002929144.1 CDS pyrB NC_012759.1 4408218 4409153 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit complement(4408218..4409153) Escherichia coli BW2952 7952514 YP_002929145.1 CDS pyrL NC_012759.1 4409157 4409291 R MG1655 equivalent: b4246; pyrBI operon leader peptide complement(4409157..4409291) Escherichia coli BW2952 7952513 YP_002929146.1 CDS yjgH NC_012759.1 4409572 4409967 R MG1655 equivalent: b4248; putative mRNA endoribonuclease complement(4409572..4409967) Escherichia coli BW2952 7955834 YP_002929147.1 CDS yjgI NC_012759.1 4410098 4410811 R MG1655 equivalent: b4249; oxidoreductase complement(4410098..4410811) Escherichia coli BW2952 7955166 YP_002929148.1 CDS yjgJ NC_012759.1 4410882 4411475 D MG1655 equivalent: b4251; putative transcriptional regulator 4410882..4411475 Escherichia coli BW2952 7955249 YP_002929149.1 CDS yjgK NC_012759.1 4411620 4412072 D MG1655 equivalent: b4252; hypothetical protein 4411620..4412072 Escherichia coli BW2952 7955641 YP_002929150.1 CDS yjgL NC_012759.1 4412195 4414009 D MG1655 equivalent: b4253; hypothetical protein 4412195..4414009 Escherichia coli BW2952 7953065 YP_002929151.1 CDS argI NC_012759.1 4414065 4415069 R catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.; ornithine carbamoyltransferase subunit I complement(4414065..4415069) Escherichia coli BW2952 7955525 YP_002929152.1 CDS rraB NC_012759.1 4415231 4415647 D MG1655 equivalent: b4255; hypothetical protein 4415231..4415647 Escherichia coli BW2952 7954428 YP_002929153.1 CDS yjgM NC_012759.1 4415792 4416295 R MG1655 equivalent: b4256; putative acetyltransferase complement(4415792..4416295) Escherichia coli BW2952 7953066 YP_002929154.1 CDS yjgN NC_012759.1 4416488 4417684 D MG1655 equivalent: b4257; hypothetical protein 4416488..4417684 Escherichia coli BW2952 7954602 YP_002929155.1 CDS valS NC_012759.1 4417740 4420595 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(4417740..4420595) Escherichia coli BW2952 7952737 YP_002929156.1 CDS holC NC_012759.1 4420595 4421038 R binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi complement(4420595..4421038) Escherichia coli BW2952 7956270 YP_002929157.1 CDS pepA NC_012759.1 4421198 4422709 R catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase complement(4421198..4422709) Escherichia coli BW2952 7953321 YP_002929158.1 CDS yjgP NC_012759.1 4422976 4424076 D MG1655 equivalent: b4261; hypothetical protein 4422976..4424076 Escherichia coli BW2952 7952470 YP_002929159.1 CDS yjgQ NC_012759.1 4424076 4425158 D MG1655 equivalent: b4262; hypothetical protein 4424076..4425158 Escherichia coli BW2952 7952738 YP_002929160.1 CDS yjgR NC_012759.1 4425319 4426821 R MG1655 equivalent: b4263; putative ATPase complement(4425319..4426821) Escherichia coli BW2952 7952739 YP_002929161.1 CDS idnR NC_012759.1 4426899 4427897 R MG1655 equivalent: b4264; DNA-binding transcriptional repressor, 5-gluconate-binding complement(4426899..4427897) Escherichia coli BW2952 7954661 YP_002929162.1 CDS idnT NC_012759.1 4427964 4429283 R MG1655 equivalent: b4265; L-idonate and D-gluconate transporter complement(4427964..4429283) Escherichia coli BW2952 7953477 YP_002929163.1 CDS idnO NC_012759.1 4429345 4430109 R Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase complement(4429345..4430109) Escherichia coli BW2952 7954143 YP_002929164.1 CDS idnD NC_012759.1 4430133 4431164 R NAD-binding; L-idonate 5-dehydrogenase complement(4430133..4431164) Escherichia coli BW2952 7952371 YP_002929165.1 CDS idnK NC_012759.1 4431381 4431944 D MG1655 equivalent: b4268; D-gluconate kinase 4431381..4431944 Escherichia coli BW2952 7954142 YP_002929166.1 CDS yjgB NC_012759.1 4431948 4432967 R MG1655 equivalent: b4269; putative alcohol dehydrogenase, Zn-dependent and NAD(P)-binding complement(4431948..4432967) Escherichia coli BW2952 7953244 YP_002929167.1 CDS insC NC_012759.1 4435030 4435395 D IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 4435030..4435395 Escherichia coli BW2952 7952166 YP_002929168.1 CDS insD NC_012759.1 4435353 4436258 D IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 4435353..4436258 Escherichia coli BW2952 7954076 YP_002929169.1 CDS yjgZ NC_012759.1 4438018 4438347 D MG1655 equivalent: b4277; KpLE2 phage protein 4438018..4438347 Escherichia coli BW2952 7954082 YP_002929170.1 CDS insG NC_012759.1 4438861 4440189 R MG1655 equivalent: b4278; KpLE2 phage-like element; IS4 putative transposase complement(4438861..4440189) Escherichia coli BW2952 7954100 YP_002929171.1 CDS yjhB NC_012759.1 4440816 4442033 D MG1655 equivalent: b4279; putative sialic acid transporter 4440816..4442033 Escherichia coli BW2952 7954086 YP_002929172.1 CDS yjhC NC_012759.1 4442045 4443163 D MG1655 equivalent: b4280; KpLE2 phage-like element; putative oxidoreductase 4442045..4443163 Escherichia coli BW2952 7954102 YP_002929173.1 CDS ythA NC_012759.1 4443206 4443331 D MG1655 equivalent: b4655; hypothetical protein 4443206..4443331 Escherichia coli BW2952 7954097 YP_002929174.1 CDS insI NC_012759.1 4444224 4445375 R MG1655 equivalent: b4284; KpLE2 phage-like element; IS30 transposase complement(4444224..4445375) Escherichia coli BW2952 7953552 YP_002929175.1 CDS fecE NC_012759.1 4447448 4448215 R Part of the FecBCDE citrate-dependent iron (III) transport system; iron-dicitrate transporter ATP-binding subunit complement(4447448..4448215) Escherichia coli BW2952 7954083 YP_002929176.1 CDS fecD NC_012759.1 4448216 4449172 R Ferric citrate binds FecA and is transported across the outer membrane while transmits a signal across the cytoplasmic membrane protein FecR. FecR transmits a signal across the membrane and activates the cytoplasmic FecI that directs the RNA polymerase to express the fecABCDE operon (which encodes the ferric citrate outer membrane receptor and the ferric citrate ABC transporter), as well as fecIR. FecD is one of two (along with FecC) integral membrane protein components of the iron dicitrate ABC transporter.; iron-dicitrate transporter subunit FecD complement(4448216..4449172) Escherichia coli BW2952 7954063 YP_002929177.1 CDS fecC NC_012759.1 4449169 4450167 R part of the FecBCDE citrate-dependent iron (III) transport system; iron-dicitrate transporter permease subunit complement(4449169..4450167) Escherichia coli BW2952 7954064 YP_002929178.1 CDS fecB NC_012759.1 4450164 4451066 R part of the ABC transporter involved in the uptake of citrate-dependent Fe(3+); iron-dicitrate transporter substrate-binding subunit complement(4450164..4451066) Escherichia coli BW2952 7954065 YP_002929179.1 CDS fecA NC_012759.1 4451111 4453435 R MG1655 equivalent: b4291; KpLE2 phage-like element; ferric citrate outer membrane transporter complement(4451111..4453435) Escherichia coli BW2952 7954066 YP_002929180.1 CDS fecR NC_012759.1 4453522 4454475 R with FecA forms the FecAR signal transduction system; ferric citrate binds FecA and transmits a signal across the outer membrane to FecR. FecR transmits a signal across the cytoplasmic membrane and activates the sigma 70 protein FecI that directs the RNA polymerase to express the fecABCDE operon; fec operon regulator FecR complement(4453522..4454475) Escherichia coli BW2952 7954062 YP_002929181.1 CDS fecI NC_012759.1 4454472 4454993 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor regulates the genes for iron dicitrate transport; RNA polymerase sigma factor FecI complement(4454472..4454993) Escherichia coli BW2952 7954104 YP_002929182.1 CDS insA NC_012759.1 4455285 4455560 D MG1655 equivalent: b4294; KpLE2 phage-like element; IS1 repressor protein InsA 4455285..4455560 Escherichia coli BW2952 7954103 YP_002929183.1 CDS yjhU NC_012759.1 4456096 4457082 R MG1655 equivalent: b4295; KpLE2 phage-like element; putative DNA-binding transcriptional regulator complement(4456096..4457082) Escherichia coli BW2952 7954069 YP_002929184.1 CDS yjhF NC_012759.1 4457429 4458778 R MG1655 equivalent: b4296; KpLE2 phage-like element; putative transporter complement(4457429..4458778) Escherichia coli BW2952 7954089 YP_002929185.1 CDS yjhG NC_012759.1 4458885 4460852 R MG1655 equivalent: b4297; hypothetical protein complement(4458885..4460852) Escherichia coli BW2952 7954101 YP_002929186.1 CDS yjhH NC_012759.1 4460863 4461768 R MG1655 equivalent: b4298; KpLE2 phage-like element; putative lyase/synthase complement(4460863..4461768) Escherichia coli BW2952 7954088 YP_002929187.1 CDS yjhI NC_012759.1 4461773 4462561 R MG1655 equivalent: b4299; KpLE2 phage-like element; putative DNA-binding transcriptional regulator complement(4461773..4462561) Escherichia coli BW2952 7954094 YP_002929188.1 CDS sgcR NC_012759.1 4462864 4463646 R MG1655 equivalent: b4300; KpLE2 phage-like element; putative DNA-binding transcriptional regulator complement(4462864..4463646) Escherichia coli BW2952 7954090 YP_002929189.1 CDS sgcE NC_012759.1 4463663 4464295 R MG1655 equivalent: b4301; epimerase complement(4463663..4464295) Escherichia coli BW2952 7954091 YP_002929190.1 CDS sgcA NC_012759.1 4464307 4464738 R MG1655 equivalent: b4302; KpLE2 phage-like element; putative phosphotransferase enzyme IIA component complement(4464307..4464738) Escherichia coli BW2952 7954093 YP_002929191.1 CDS sgcQ NC_012759.1 4464869 4465675 R MG1655 equivalent: b4303; KpLE2 phage-like element; putative nucleoside triphosphatase complement(4464869..4465675) Escherichia coli BW2952 7952201 YP_002929192.1 CDS sgcC NC_012759.1 4465688 4467001 R MG1655 equivalent: b4304; KpLE2 phage-like element; putative phosphotransferase enzyme IIC component complement(4465688..4467001) Escherichia coli BW2952 7954096 YP_002929193.1 CDS sgcB NC_012759.1 4467013 4467291 R MG1655 equivalent: b4565; putative enzyme IIB component of PTS complement(4467013..4467291) Escherichia coli BW2952 7954099 YP_002929194.1 CDS sgcX NC_012759.1 4467288 4468409 R MG1655 equivalent: b4305; putative endoglucanase with Zn-dependent exopeptidase domain protein complement(4467288..4468409) Escherichia coli BW2952 7954853 YP_002929195.1 CDS yjhP NC_012759.1 4469195 4469941 R MG1655 equivalent: b4306; KpLE2 phage-like element; putative methyltransferase complement(4469195..4469941) Escherichia coli BW2952 7954092 YP_002929196.1 CDS yjhQ NC_012759.1 4469997 4470542 R MG1655 equivalent: b4307; KpLE2 phage-like element; putative acetyltransferase complement(4469997..4470542) Escherichia coli BW2952 7954095 YP_002929197.1 CDS yjhX NC_012759.1 4470554 4470811 R MG1655 equivalent: b4566; hypothetical protein complement(4470554..4470811) Escherichia coli BW2952 7954087 YP_002929198.1 CDS yjhS NC_012759.1 4473372 4474352 R MG1655 equivalent: b4309; hypothetical protein complement(4473372..4474352) Escherichia coli BW2952 7952913 YP_002929199.1 CDS nanM NC_012759.1 4474417 4475523 R MG1655 equivalent: b4310; N-acetylneuraminic acid mutarotase complement(4474417..4475523) Escherichia coli BW2952 7952900 YP_002929200.1 CDS nanC NC_012759.1 4475543 4476259 R MG1655 equivalent: b4311; N-acetylnuraminic acid outer membrane channel protein complement(4475543..4476259) Escherichia coli BW2952 7952901 YP_002929201.1 CDS BWG_4010 NC_012759.1 4478031 4478534 D Insertion element IS1 1/5/6 protein insB 4478031..4478534 Escherichia coli BW2952 7954347 YP_002929202.1 CDS fimE NC_012759.1 4478536 4479141 D inversion of on/off regulator of fimA; tyrosine recombinase 4478536..4479141 Escherichia coli BW2952 7954004 YP_002929203.1 CDS fimA NC_012759.1 4479623 4480171 D MG1655 equivalent: b4314; major type 1 subunit fimbrin (pilin) 4479623..4480171 Escherichia coli BW2952 7956222 YP_002929204.1 CDS fimI NC_012759.1 4480236 4480775 D MG1655 equivalent: b4315; type 1 pilus biosynthesis fimbrial protein 4480236..4480775 Escherichia coli BW2952 7954196 YP_002929205.1 CDS fimC NC_012759.1 4480812 4481537 D MG1655 equivalent: b4316; chaperone, periplasmic 4480812..4481537 Escherichia coli BW2952 7953577 YP_002929206.1 CDS fimD NC_012759.1 4481604 4484240 D MG1655 equivalent: b4317; outer membrane usher protein, type 1 fimbrial synthesis 4481604..4484240 Escherichia coli BW2952 7952630 YP_002929207.1 CDS fimF NC_012759.1 4484250 4484780 D MG1655 equivalent: b4318; minor component of type 1 fimbriae 4484250..4484780 Escherichia coli BW2952 7954451 YP_002929208.1 CDS fimG NC_012759.1 4484793 4485296 D MG1655 equivalent: b4319; minor component of type 1 fimbriae 4484793..4485296 Escherichia coli BW2952 7954264 YP_002929209.1 CDS fimH NC_012759.1 4485316 4486218 D MG1655 equivalent: b4320; minor component of type 1 fimbriae 4485316..4486218 Escherichia coli BW2952 7954265 YP_002929210.1 CDS gntP NC_012759.1 4486461 4487804 R MG1655 equivalent: b4321; fructuronate transporter complement(4486461..4487804) Escherichia coli BW2952 7954266 YP_002929211.1 CDS uxuA NC_012759.1 4488144 4489328 D catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 4488144..4489328 Escherichia coli BW2952 7953641 YP_002929212.1 CDS uxuB NC_012759.1 4489409 4490869 D MG1655 equivalent: b4323; D-mannonate oxidoreductase, NAD-binding 4489409..4490869 Escherichia coli BW2952 7954213 YP_002929213.1 CDS uxuR NC_012759.1 4491084 4491857 D regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR 4491084..4491857 Escherichia coli BW2952 7953297 YP_002929214.1 CDS yjiC NC_012759.1 4491998 4492828 R MG1655 equivalent: b4325; hypothetical protein complement(4491998..4492828) Escherichia coli BW2952 7953471 YP_002929215.1 CDS iraD NC_012759.1 4493501 4493893 D inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS; DNA replication/recombination/repair protein 4493501..4493893 Escherichia coli BW2952 7955430 YP_002929216.1 CDS yjiE NC_012759.1 4493886 4494797 R MG1655 equivalent: b4327; putative DNA-binding transcriptional regulator complement(4493886..4494797) Escherichia coli BW2952 7953331 YP_002929217.1 CDS iadA NC_012759.1 4494862 4496034 R MG1655 equivalent: b4328; isoaspartyl dipeptidase complement(4494862..4496034) Escherichia coli BW2952 7954786 YP_002929218.1 CDS yjiG NC_012759.1 4496047 4496508 R MG1655 equivalent: b4329; hypothetical protein complement(4496047..4496508) Escherichia coli BW2952 7954047 YP_002929219.1 CDS yjiH NC_012759.1 4496505 4497188 R MG1655 equivalent: b4330; hypothetical protein complement(4496505..4497188) Escherichia coli BW2952 7952694 YP_002929220.1 CDS kptA NC_012759.1 4497438 4497992 D in yeast cells this enzyme removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate; functions in tRNA splicing; the function and substrate of bacterial enzymes in organisms that do not perform splicing is unknown; RNA 2'-phosphotransferase-like protein 4497438..4497992 Escherichia coli BW2952 7952695 YP_002929221.1 CDS yjiJ NC_012759.1 4498005 4499183 R MG1655 equivalent: b4332; putative inner membrane protein complement(4498005..4499183) Escherichia coli BW2952 7952270 YP_002929222.1 CDS yjiK NC_012759.1 4499251 4500111 R MG1655 equivalent: b4333; hypothetical protein complement(4499251..4500111) Escherichia coli BW2952 7955019 YP_002929223.1 CDS yjiL NC_012759.1 4500429 4501196 R MG1655 equivalent: b4334; putative ATPase, activator of (R)-hydroxyglutaryl-CoA dehydratase complement(4500429..4501196) Escherichia coli BW2952 7952902 YP_002929224.1 CDS yjiM NC_012759.1 4501206 4502357 R MG1655 equivalent: b4335; putative 2-hydroxyglutaryl-CoA dehydratase complement(4501206..4502357) Escherichia coli BW2952 7954662 YP_002929225.1 CDS yjiN NC_012759.1 4502473 4503753 R MG1655 equivalent: b4336; hypothetical protein complement(4502473..4503753) Escherichia coli BW2952 7954587 YP_002929226.1 CDS mdtM NC_012759.1 4503794 4505026 R MG1655 equivalent: b4337; multidrug efflux system protein complement(4503794..4505026) Escherichia coli BW2952 7952696 YP_002929227.1 CDS yjiR NC_012759.1 4506669 4508081 R MG1655 equivalent: b4340; fused putative DNA-binding transcriptional regulator/putative aminotransferase complement(4506669..4508081) Escherichia coli BW2952 7954300 YP_002929228.1 CDS yjiS NC_012759.1 4508258 4508422 D MG1655 equivalent: b4341; hypothetical protein 4508258..4508422 Escherichia coli BW2952 7953712 YP_002929229.1 CDS mcrC NC_012759.1 4513419 4514465 R McrC protein together with McrB forms the McrBC restriction system; recognizes N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines); appears to act against 5-methylcytosine preceded by a purine residue; MrcC modulates the specificty of McrB and has DNA cleavage activity; 5-methylcytosine-specific restriction enzyme subunit McrC complement(4513419..4514465) Escherichia coli BW2952 7953067 YP_002929230.1 CDS mcrB NC_012759.1 4514465 4515844 R McrB protein together with McrC forms the McrBC restriction system; recognizes N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines); appears to act against 5-methylcytosine preceded by a purine residue; 5-methylcytosine-specific restriction enzyme subunit McrB complement(4514465..4515844) Escherichia coli BW2952 7952373 YP_002929231.1 CDS symE NC_012759.1 4516006 4516347 R involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE complement(4516006..4516347) Escherichia coli BW2952 7952372 YP_002929232.1 CDS hsdS NC_012759.1 4516575 4517969 R specificity determinant for hsdM and hsdR; EcoKI restriction-modification system protein HsdS complement(4516575..4517969) Escherichia coli BW2952 7952202 YP_002929233.1 CDS hsdM NC_012759.1 4517966 4519555 R MG1655 equivalent: b4349; DNA methylase M complement(4517966..4519555) Escherichia coli BW2952 7956060 YP_002929234.1 CDS hsdR NC_012759.1 4519756 4523322 R restriction endonuclease; the EcoKI enzyme recognizes 5'-AACN(6)GTGC-3'; subunit R is required for both nuclease and ATPase activities; type I restriction enzyme EcoKI subunit R complement(4519756..4523322) Escherichia coli BW2952 7953313 YP_002929235.1 CDS mrr NC_012759.1 4523456 4524370 D MG1655 equivalent: b4351; methylated adenine and cytosine restriction protein 4523456..4524370 Escherichia coli BW2952 7953519 YP_002929236.1 CDS yjiA NC_012759.1 4524416 4525372 R MG1655 equivalent: b4352; putative GTP-binding protein YjiA complement(4524416..4525372) Escherichia coli BW2952 7954253 YP_002929237.1 CDS yjiX NC_012759.1 4525383 4525586 R MG1655 equivalent: b4353; hypothetical protein complement(4525383..4525586) Escherichia coli BW2952 7954939 YP_002929238.1 CDS yjiY NC_012759.1 4525636 4527786 R MG1655 equivalent: b4354; putative inner membrane protein complement(4525636..4527786) Escherichia coli BW2952 7952904 YP_002929239.1 CDS tsr NC_012759.1 4528164 4529819 D MG1655 equivalent: b4355; methyl-accepting chemotaxis protein I, serine sensor receptor 4528164..4529819 Escherichia coli BW2952 7955020 YP_002929240.1 CDS yjjL NC_012759.1 4529868 4531229 R MG1655 equivalent: b4356; putative transporter complement(4529868..4531229) Escherichia coli BW2952 7954248 YP_002929241.1 CDS yjjM NC_012759.1 4531444 4532358 R MG1655 equivalent: b4357; putative DNA-binding transcriptional regulator complement(4531444..4532358) Escherichia coli BW2952 7955676 YP_002929242.1 CDS yjjN NC_012759.1 4532506 4533519 D MG1655 equivalent: b4358; putative oxidoreductase, Zn-dependent and NAD(P)-binding 4532506..4533519 Escherichia coli BW2952 7954787 YP_002929243.1 CDS mdoB NC_012759.1 4533657 4535948 R catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I complement(4533657..4535948) Escherichia coli BW2952 7955266 YP_002929244.1 CDS yjjA NC_012759.1 4536202 4536696 R MG1655 equivalent: b4360; hypothetical protein complement(4536202..4536696) Escherichia coli BW2952 7954535 YP_002929245.1 CDS dnaC NC_012759.1 4536745 4537482 R acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC complement(4536745..4537482) Escherichia coli BW2952 7952905 YP_002929246.1 CDS dnaT NC_012759.1 4537485 4538024 R This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI complement(4537485..4538024) Escherichia coli BW2952 7953300 YP_002929247.1 CDS yjjB NC_012759.1 4538131 4538604 R MG1655 equivalent: b4363; hypothetical protein complement(4538131..4538604) Escherichia coli BW2952 7953301 YP_002929248.1 CDS yjjP NC_012759.1 4538595 4539365 R MG1655 equivalent: b4364; putative inner membrane protein complement(4538595..4539365) Escherichia coli BW2952 7952697 YP_002929249.1 CDS yjjQ NC_012759.1 4539984 4540709 D MG1655 equivalent: b4365; putative DNA-binding transcriptional regulator 4539984..4540709 Escherichia coli BW2952 7955021 YP_002929250.1 CDS bglJ NC_012759.1 4540817 4541344 D regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 4540817..4541344 Escherichia coli BW2952 7954819 YP_002929251.1 CDS fhuF NC_012759.1 4541382 4542170 R MG1655 equivalent: b4367; ferric hydroximate transport ferric iron reductase complement(4541382..4542170) Escherichia coli BW2952 7953384 YP_002929252.1 CDS yjjZ NC_012759.1 4542311 4542547 D MG1655 equivalent: b4567; hypothetical protein 4542311..4542547 Escherichia coli BW2952 7953568 YP_002929253.1 CDS rsmC NC_012759.1 4543176 4544207 R 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase complement(4543176..4544207) Escherichia coli BW2952 7952077 YP_002929254.1 CDS holD NC_012759.1 4544310 4544723 D with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 4544310..4544723 Escherichia coli BW2952 7952222 YP_002929255.1 CDS rimI NC_012759.1 4544692 4545138 D alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 4544692..4545138 Escherichia coli BW2952 7953324 YP_002929256.1 CDS yjjG NC_012759.1 4545153 4545830 D manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 4545153..4545830 Escherichia coli BW2952 7952397 YP_002929257.1 CDS prfC NC_012759.1 4545921 4547510 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 4545921..4547510 Escherichia coli BW2952 7953506 YP_002929258.1 CDS osmY NC_012759.1 4547903 4548508 D MG1655 equivalent: b4376; hypothetical protein 4547903..4548508 Escherichia coli BW2952 7954476 YP_002929259.1 CDS ytjA NC_012759.1 4548635 4548796 D MG1655 equivalent: b4568; hypothetical protein 4548635..4548796 Escherichia coli BW2952 7954497 YP_002929260.1 CDS yjjU NC_012759.1 4548918 4549991 D MG1655 equivalent: b4377; putative esterase 4548918..4549991 Escherichia coli BW2952 7955541 YP_002929261.1 CDS yjjV NC_012759.1 4549988 4550767 D MG1655 equivalent: b4378; putative deoxyribonuclease YjjV 4549988..4550767 Escherichia coli BW2952 7954864 YP_002929262.1 CDS yjjW NC_012759.1 4551187 4552050 R MG1655 equivalent: b4379; putative pyruvate formate lyase activating enzyme complement(4551187..4552050) Escherichia coli BW2952 7954826 YP_002929263.1 CDS yjjI NC_012759.1 4552022 4553572 R MG1655 equivalent: b4380; hypothetical protein complement(4552022..4553572) Escherichia coli BW2952 7955552 YP_002929264.1 CDS deoC NC_012759.1 4553830 4554609 D catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 4553830..4554609 Escherichia coli BW2952 7952906 YP_002929265.1 CDS deoA NC_012759.1 4554736 4556058 D Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 4554736..4556058 Escherichia coli BW2952 7952258 YP_002929266.1 CDS deoB NC_012759.1 4556110 4557333 D catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 4556110..4557333 Escherichia coli BW2952 7956149 YP_002929267.1 CDS deoD NC_012759.1 4557390 4558109 D catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 4557390..4558109 Escherichia coli BW2952 7954547 YP_002929268.1 CDS yjjJ NC_012759.1 4558276 4559607 D MG1655 equivalent: b4385; hypothetical protein 4558276..4559607 Escherichia coli BW2952 7955825 YP_002929269.1 CDS lplA NC_012759.1 4559608 4560624 R Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A complement(4559608..4560624) Escherichia coli BW2952 7954820 YP_002929270.1 CDS ytjB NC_012759.1 4560652 4561296 R MG1655 equivalent: b4387; hypothetical protein complement(4560652..4561296) Escherichia coli BW2952 7954148 YP_002929271.1 CDS serB NC_012759.1 4561402 4562370 D catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 4561402..4562370 Escherichia coli BW2952 7952907 YP_002929272.1 CDS radA NC_012759.1 4562419 4563801 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 4562419..4563801 Escherichia coli BW2952 7952325 YP_002929273.1 CDS nadR NC_012759.1 4563822 4565054 D catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 4563822..4565054 Escherichia coli BW2952 7955566 YP_002929274.1 CDS yjjK NC_012759.1 4565362 4567029 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein complement(4565362..4567029) Escherichia coli BW2952 7952566 YP_002929275.1 CDS slt NC_012759.1 4567240 4569177 D catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 4567240..4569177 Escherichia coli BW2952 7953731 YP_002929276.1 CDS trpR NC_012759.1 4569267 4569593 D When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 4569267..4569593 Escherichia coli BW2952 7954189 YP_002929277.1 CDS yjjX NC_012759.1 4569740 4570252 R pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase complement(4569740..4570252) Escherichia coli BW2952 7953482 YP_002929278.1 CDS ytjC NC_012759.1 4570304 4570951 D catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 4570304..4570951 Escherichia coli BW2952 7956127 YP_002929279.1 CDS rob NC_012759.1 4570948 4571817 R MG1655 equivalent: b4396; DNA-binding transcriptional activator complement(4570948..4571817) Escherichia coli BW2952 7954537 YP_002929280.1 CDS creA NC_012759.1 4572028 4572501 D MG1655 equivalent: b4397; hypothetical protein 4572028..4572501 Escherichia coli BW2952 7953374 YP_002929281.1 CDS creB NC_012759.1 4572514 4573203 D response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 4572514..4573203 Escherichia coli BW2952 7953068 YP_002929282.1 CDS creC NC_012759.1 4573203 4574627 D part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 4573203..4574627 Escherichia coli BW2952 7953349 YP_002929283.1 CDS creD NC_012759.1 4574685 4576037 D MG1655 equivalent: b4400; hypothetical protein 4574685..4576037 Escherichia coli BW2952 7956016 YP_002929284.1 CDS arcA NC_012759.1 4576097 4576813 R MG1655 equivalent: b4401; two-component response regulator complement(4576097..4576813) Escherichia coli BW2952 7953998 YP_002929285.1 CDS yjjY NC_012759.1 4576909 4577049 D MG1655 equivalent: b4402; hypothetical protein 4576909..4577049 Escherichia coli BW2952 7953343 YP_002929286.1 CDS yjtD NC_012759.1 4577449 4578135 D member of the SPOUT superfamily of methyltransferases; putative RNA methyltransferase 4577449..4578135 Escherichia coli BW2952 7955526 BWG_4118 tRNA ileV NC_012759.1 225380 225456 D tRNA-Ile 225380..225456 Escherichia coli BW2952 7952100 BWG_4119 tRNA alaV NC_012759.1 225499 225574 D tRNA-Ala 225499..225574 Escherichia coli BW2952 7952115 BWG_4120 tRNA aspU NC_012759.1 228927 229003 D tRNA-Asp 228927..229003 Escherichia coli BW2952 7952102 BWG_4121 tRNA aspV NC_012759.1 236930 237006 D tRNA-Asp 236930..237006 Escherichia coli BW2952 7953319 BWG_4122 tRNA thrW NC_012759.1 262094 262169 D tRNA-Thr 262094..262169 Escherichia coli BW2952 7953771 BWG_4123 tRNA argU NC_012759.1 466706 466782 D tRNA-Arg 466706..466782 Escherichia coli BW2952 7954746 BWG_4124 tRNA pauD NC_012759.1 488040 488084 D tRNA-OTHER 488040..488084 Escherichia coli BW2952 7953281 BWG_4125 tRNA glnX NC_012759.1 598413 598487 R tRNA-Gln complement(598413..598487) Escherichia coli BW2952 7952264 BWG_4126 tRNA glnV NC_012759.1 598525 598599 R tRNA-Gln complement(598525..598599) Escherichia coli BW2952 7952041 BWG_4127 tRNA metU NC_012759.1 598647 598723 R tRNA-Met complement(598647..598723) Escherichia coli BW2952 7952042 BWG_4128 tRNA glnW NC_012759.1 598739 598813 R tRNA-Gln complement(598739..598813) Escherichia coli BW2952 7952043 BWG_4129 tRNA glnU NC_012759.1 598848 598922 R tRNA-Gln complement(598848..598922) Escherichia coli BW2952 7952044 BWG_4130 tRNA leuW NC_012759.1 598946 599030 R tRNA-Leu complement(598946..599030) Escherichia coli BW2952 7952045 BWG_4131 tRNA metT NC_012759.1 599040 599116 R tRNA-Met complement(599040..599116) Escherichia coli BW2952 7952046 BWG_4132 tRNA lysT NC_012759.1 682537 682612 D tRNA-Lys 682537..682612 Escherichia coli BW2952 7955447 BWG_4133 tRNA valT NC_012759.1 682748 682823 D tRNA-Val 682748..682823 Escherichia coli BW2952 7952122 BWG_4134 tRNA lysW NC_012759.1 682826 682901 D tRNA-Lys 682826..682901 Escherichia coli BW2952 7952123 BWG_4135 tRNA valZ NC_012759.1 683051 683126 D tRNA-Val 683051..683126 Escherichia coli BW2952 7952124 BWG_4136 tRNA lysY NC_012759.1 683130 683205 D tRNA-Lys 683130..683205 Escherichia coli BW2952 7952125 BWG_4137 tRNA lysZ NC_012759.1 683352 683427 D tRNA-Lys 683352..683427 Escherichia coli BW2952 7952126 BWG_4138 tRNA lysQ NC_012759.1 683560 683635 D tRNA-Lys 683560..683635 Escherichia coli BW2952 7952127 BWG_4139 tRNA lysQ NC_012759.1 683768 683843 D tRNA-Lys 683768..683843 Escherichia coli BW2952 7952128 BWG_4140 tRNA serW NC_012759.1 828075 828162 R tRNA-Ser complement(828075..828162) Escherichia coli BW2952 7952524 BWG_4141 tRNA serT NC_012759.1 933816 933903 R tRNA-Ser complement(933816..933903) Escherichia coli BW2952 7953996 BWG_4142 tRNA serX NC_012759.1 1000713 1000800 R tRNA-Ser complement(1000713..1000800) Escherichia coli BW2952 7955032 BWG_4143 tRNA tyrV NC_012759.1 1175188 1175272 R tRNA-Tyr complement(1175188..1175272) Escherichia coli BW2952 7955330 BWG_4144 tRNA tyrT NC_012759.1 1175482 1175566 R tRNA-Tyr complement(1175482..1175566) Escherichia coli BW2952 7952051 BWG_4145 tRNA valV NC_012759.1 1636518 1636594 D tRNA-Val 1636518..1636594 Escherichia coli BW2952 7952806 BWG_4146 tRNA valW NC_012759.1 1636599 1636675 D tRNA-Val 1636599..1636675 Escherichia coli BW2952 7952130 BWG_4147 tRNA leuZ NC_012759.1 1882322 1882408 R tRNA-Leu complement(1882322..1882408) Escherichia coli BW2952 7952745 BWG_4148 tRNA cysT NC_012759.1 1882421 1882494 R tRNA-Cys complement(1882421..1882494) Escherichia coli BW2952 7952053 BWG_4149 tRNA glyW NC_012759.1 1882549 1882624 R tRNA-Gly complement(1882549..1882624) Escherichia coli BW2952 7952054 BWG_4150 tRNA serU NC_012759.1 1933975 1934064 R tRNA-Ser complement(1933975..1934064) Escherichia coli BW2952 7954707 BWG_4151 tRNA asnT NC_012759.1 1935056 1935131 D tRNA-Asn 1935056..1935131 Escherichia coli BW2952 7952989 BWG_4152 tRNA asnW NC_012759.1 1948534 1948609 R tRNA-Asn complement(1948534..1948609) Escherichia coli BW2952 7952990 BWG_4153 tRNA asnU NC_012759.1 1950358 1950433 D tRNA-Asn 1950358..1950433 Escherichia coli BW2952 7955172 BWG_4154 tRNA asnV NC_012759.1 1952767 1952842 D tRNA-Asn 1952767..1952842 Escherichia coli BW2952 7953426 BWG_4155 tRNA proL NC_012759.1 2170038 2170114 D tRNA-Pro 2170038..2170114 Escherichia coli BW2952 7954979 BWG_4156 tRNA argW NC_012759.1 2350136 2350210 D tRNA-Arg 2350136..2350210 Escherichia coli BW2952 7955053 BWG_4157 tRNA pawZ NC_012759.1 2360411 2360425 D tRNA-OTHER 2360411..2360425 Escherichia coli BW2952 7955944 BWG_4158 tRNA alaX NC_012759.1 2401868 2401943 R tRNA-Ala complement(2401868..2401943) Escherichia coli BW2952 7954724 BWG_4159 tRNA alaW NC_012759.1 2401983 2402058 R tRNA-Ala complement(2401983..2402058) Escherichia coli BW2952 7952058 BWG_4160 tRNA valU NC_012759.1 2404758 2404833 D tRNA-Val 2404758..2404833 Escherichia coli BW2952 7953833 BWG_4161 tRNA valX NC_012759.1 2404878 2404953 D tRNA-Val 2404878..2404953 Escherichia coli BW2952 7952138 BWG_4162 tRNA valY NC_012759.1 2405000 2405075 D tRNA-Val 2405000..2405075 Escherichia coli BW2952 7952139 BWG_4163 tRNA lysV NC_012759.1 2405080 2405155 D tRNA-Lys 2405080..2405155 Escherichia coli BW2952 7952140 BWG_4164 tRNA gltW NC_012759.1 2613205 2613280 R tRNA-Glu complement(2613205..2613280) Escherichia coli BW2952 7952035 BWG_4165 tRNA ileY NC_012759.1 2669596 2669671 R tRNA-Ile complement(2669596..2669671) Escherichia coli BW2952 7952428 BWG_4166 tRNA argQ NC_012759.1 2701618 2701694 R tRNA-Arg complement(2701618..2701694) Escherichia coli BW2952 7954959 BWG_4167 tRNA argZ NC_012759.1 2701893 2701969 R tRNA-Arg complement(2701893..2701969) Escherichia coli BW2952 7952062 BWG_4168 tRNA argY NC_012759.1 2702032 2702108 R tRNA-Arg complement(2702032..2702108) Escherichia coli BW2952 7952063 BWG_4169 tRNA argV NC_012759.1 2702307 2702383 R tRNA-Arg complement(2702307..2702383) Escherichia coli BW2952 7952064 BWG_4170 tRNA serV NC_012759.1 2702387 2702479 R tRNA-Ser complement(2702387..2702479) Escherichia coli BW2952 7952065 BWG_4171 tRNA metZ NC_012759.1 2832557 2832633 D tRNA-Met 2832557..2832633 Escherichia coli BW2952 7954239 BWG_4172 tRNA metW NC_012759.1 2832667 2832743 D tRNA-Met 2832667..2832743 Escherichia coli BW2952 7952142 BWG_4173 tRNA metV NC_012759.1 2832777 2832853 D tRNA-Met 2832777..2832853 Escherichia coli BW2952 7952143 BWG_4174 tRNA glyU NC_012759.1 2884154 2884227 R tRNA-Gly complement(2884154..2884227) Escherichia coli BW2952 7954073 BWG_4175 tRNA pheV NC_012759.1 2995536 2995611 D tRNA-Phe 2995536..2995611 Escherichia coli BW2952 7955062 BWG_4176 tRNA ileX NC_012759.1 3100768 3100843 D tRNA-Ile 3100768..3100843 Escherichia coli BW2952 7953752 BWG_4177 tRNA metY NC_012759.1 3203383 3203459 R tRNA-Met complement(3203383..3203459) Escherichia coli BW2952 7952872 BWG_4178 tRNA leuU NC_012759.1 3207242 3207328 R tRNA-Leu complement(3207242..3207328) Escherichia coli BW2952 7954978 BWG_4179 tRNA thrV NC_012759.1 3308750 3308825 R tRNA-Thr complement(3308750..3308825) Escherichia coli BW2952 7952037 BWG_4180 tRNA alaU NC_012759.1 3312137 3312212 R tRNA-Ala complement(3312137..3312212) Escherichia coli BW2952 7952039 BWG_4181 tRNA ileU NC_012759.1 3312255 3312331 R tRNA-Ile complement(3312255..3312331) Escherichia coli BW2952 7952071 BWG_4182 tRNA proK NC_012759.1 3594965 3595041 R tRNA-Pro complement(3594965..3595041) Escherichia coli BW2952 7953268 BWG_4183 tRNA selC NC_012759.1 3722578 3722672 D tRNA-Sec 3722578..3722672 Escherichia coli BW2952 7955668 BWG_4185 tRNA gltU NC_012759.1 3831127 3831202 D tRNA-Glu 3831127..3831202 Escherichia coli BW2952 7952103 BWG_4186 tRNA aspT NC_012759.1 3834564 3834640 D tRNA-Asp 3834564..3834640 Escherichia coli BW2952 7952105 BWG_4187 tRNA trpT NC_012759.1 3834649 3834724 D tRNA-Trp 3834649..3834724 Escherichia coli BW2952 7952149 BWG_4188 tRNA argX NC_012759.1 3870067 3870143 D tRNA-Arg 3870067..3870143 Escherichia coli BW2952 7955712 BWG_4189 tRNA hisR NC_012759.1 3870201 3870277 D tRNA-His 3870201..3870277 Escherichia coli BW2952 7952151 BWG_4190 tRNA leuT NC_012759.1 3870298 3870384 D tRNA-Leu 3870298..3870384 Escherichia coli BW2952 7952152 BWG_4191 tRNA proM NC_012759.1 3870427 3870503 D tRNA-Pro 3870427..3870503 Escherichia coli BW2952 7952153 BWG_4192 tRNA ileT NC_012759.1 3924833 3924909 D tRNA-Ile 3924833..3924909 Escherichia coli BW2952 7952106 BWG_4193 tRNA alaT NC_012759.1 3924952 3925027 D tRNA-Ala 3924952..3925027 Escherichia coli BW2952 7952155 BWG_4195 tRNA thrU NC_012759.1 4063091 4063166 D tRNA-Thr 4063091..4063166 Escherichia coli BW2952 7954464 BWG_4196 tRNA tyrU NC_012759.1 4063175 4063259 D tRNA-Tyr 4063175..4063259 Escherichia coli BW2952 7952158 BWG_4197 tRNA glyT NC_012759.1 4063376 4063450 D tRNA-Gly 4063376..4063450 Escherichia coli BW2952 7952159 BWG_4198 tRNA thrT NC_012759.1 4063457 4063532 D tRNA-Thr 4063457..4063532 Escherichia coli BW2952 7952160 BWG_4199 tRNA gltV NC_012759.1 4097477 4097552 D tRNA-Glu 4097477..4097552 Escherichia coli BW2952 7952112 BWG_4200 tRNA pheU NC_012759.1 4299309 4299384 R tRNA-Phe complement(4299309..4299384) Escherichia coli BW2952 7953373 BWG_4201 tRNA glyV NC_012759.1 4329118 4329193 D tRNA-Gly 4329118..4329193 Escherichia coli BW2952 7954427 BWG_4202 tRNA glyX NC_012759.1 4329230 4329305 D tRNA-Gly 4329230..4329305 Escherichia coli BW2952 7952163 BWG_4203 tRNA glyY NC_012759.1 4329341 4329416 D tRNA-Gly 4329341..4329416 Escherichia coli BW2952 7952164 BWG_4204 tRNA leuX NC_012759.1 4433163 4433247 D tRNA-Leu 4433163..4433247 Escherichia coli BW2952 7954626 BWG_4205 tRNA leuV NC_012759.1 4542586 4542672 R tRNA-Leu complement(4542586..4542672) Escherichia coli BW2952 7955540 BWG_4206 tRNA leuP NC_012759.1 4542707 4542793 R tRNA-Leu complement(4542707..4542793) Escherichia coli BW2952 7952075 BWG_4207 tRNA leuQ NC_012759.1 4542822 4542908 R tRNA-Leu complement(4542822..4542908) Escherichia coli BW2952 7952076 BWG_4096 rRNA rrsH NC_012759.1 223770 225311 D 16S ribosomal RNA of rrnH operon 223770..225311 Escherichia coli BW2952 7953206 BWG_4097 rRNA rrlH NC_012759.1 225758 228661 D 23S ribosomal RNA of rrnH operon 225758..228661 Escherichia coli BW2952 7952116 BWG_4098 rRNA rrfH NC_012759.1 228755 228874 D 5S ribosomal RNA of rrnH operon 228755..228874 Escherichia coli BW2952 7952101 BWG_4099 rRNA rrfG NC_012759.1 2609896 2610015 R 5S ribosomal RNA of rrnG operon complement(2609896..2610015) Escherichia coli BW2952 7952459 BWG_4100 rRNA rrlG NC_012759.1 2610108 2613011 R 23S ribosomal RNA of rrnG operon complement(2610108..2613011) Escherichia coli BW2952 7952034 BWG_4101 rRNA rrsG NC_012759.1 2613452 2614991 R 16S ribosomal RNA of rrnG operon complement(2613452..2614991) Escherichia coli BW2952 7952060 BWG_4102 rRNA rrfF NC_012759.1 3308593 3308712 R 5S ribosomal RNA of rrnD operon complement(3308593..3308712) Escherichia coli BW2952 7954644 BWG_4103 rRNA rrfD NC_012759.1 3308838 3308957 R 5S ribosomal RNA of rrnD operon complement(3308838..3308957) Escherichia coli BW2952 7952070 BWG_4104 rRNA rrlD NC_012759.1 3309050 3311953 R 23S ribosomal RNA of rrnD operon complement(3309050..3311953) Escherichia coli BW2952 7952038 BWG_4105 rRNA rrsD NC_012759.1 3312400 3313941 R 16S ribosomal RNA of rrnD operon complement(3312400..3313941) Escherichia coli BW2952 7952072 BWG_4106 rRNA rrsC NC_012759.1 3829500 3831041 D 16S ribosomal RNA of rrnC operon 3829500..3831041 Escherichia coli BW2952 7955630 BWG_4107 rRNA rrlC NC_012759.1 3831396 3834299 D 23S ribosomal RNA of rrnC operon 3831396..3834299 Escherichia coli BW2952 7952148 BWG_4108 rRNA rrfC NC_012759.1 3834392 3834511 D 5S ribosomal RNA of rrnC operon 3834392..3834511 Escherichia coli BW2952 7952104 BWG_4109 rRNA rrsA NC_012759.1 3923223 3924764 D 16S ribosomal RNA of rrnA operon 3923223..3924764 Escherichia coli BW2952 7955817 BWG_4110 rRNA rrlA NC_012759.1 3925211 3928115 D 23S ribosomal RNA of rrnA operon 3925211..3928115 Escherichia coli BW2952 7952156 BWG_4111 rRNA rrfA NC_012759.1 3928209 3928328 D 5S ribosomal RNA of rrnA operon 3928209..3928328 Escherichia coli BW2952 7952107 BWG_4112 rRNA rrsB NC_012759.1 4054351 4055892 D 16S ribosomal RNA of rrnB operon 4054351..4055892 Escherichia coli BW2952 7953821 BWG_4113 rRNA rrlB NC_012759.1 4056344 4059247 D 23S ribosomal RNA of rrnB operon 4056344..4059247 Escherichia coli BW2952 7952157 BWG_4114 rRNA rrfB NC_012759.1 4059340 4059459 D 5S ribosomal RNA of rrnB operon 4059340..4059459 Escherichia coli BW2952 7952110 BWG_4115 rRNA rrsE NC_012759.1 4095850 4097391 D 16S ribosomal RNA of rrnE operon 4095850..4097391 Escherichia coli BW2952 7953688 BWG_4116 rRNA rrlE NC_012759.1 4097746 4100649 D 23S ribosomal RNA of rrnE operon 4097746..4100649 Escherichia coli BW2952 7952162 BWG_4117 rRNA rrfE NC_012759.1 4100743 4100862 D 5S ribosomal RNA of rrnE operon 4100743..4100862 Escherichia coli BW2952 7952113