-- dump date 20140619_081721 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 199310000001 SEQ_END SEQ_END NC_004431.1 5231428 5231428 DR NC_004431.1; contig end 5231428..5231428 Escherichia coli CFT073 NP_751957.1 CDS thrL NC_004431.1 190 255 D involved in threonine biosynthesis; controls the expression of the thrLABC operon; thr operon leader peptide 190..255 Escherichia coli CFT073 1040154 NP_751958.1 CDS c0002 NC_004431.1 534 911 D Residues 2 to 125 of 125 are 94.35 pct identical to residues 29 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein 534..911 Escherichia coli CFT073 1035914 NP_751959.2 CDS thrA NC_004431.1 1048 3510 D multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 1048..3510 Escherichia coli CFT073 1038322 NP_751960.1 CDS thrB NC_004431.1 3512 4444 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 3512..4444 Escherichia coli CFT073 1038469 NP_751961.1 CDS thrC NC_004431.1 4445 5731 D catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 4445..5731 Escherichia coli CFT073 1036001 NP_751962.1 CDS c0006 NC_004431.1 5799 5948 D hypothetical protein 5799..5948 Escherichia coli CFT073 1037959 NP_751963.1 CDS yaaX NC_004431.1 5945 6241 D Escherichia coli K-12 ortholog: b0005; Escherichia coli O157:H7 ortholog: z0005; hypothetical protein 5945..6241 Escherichia coli CFT073 1038052 NP_751964.1 CDS c0008 NC_004431.1 6021 6269 R hypothetical protein complement(6021..6269) Escherichia coli CFT073 1038110 NP_751965.1 CDS c0009 NC_004431.1 6060 6323 D hypothetical protein 6060..6323 Escherichia coli CFT073 1035917 NP_751966.1 CDS yaaA NC_004431.1 6301 7077 R Escherichia coli K-12 ortholog: b0006; Escherichia coli O157:H7 ortholog: z0006; hypothetical protein complement(6301..7077) Escherichia coli CFT073 1037723 NP_751967.1 CDS yaaJ NC_004431.1 7147 8577 R Escherichia coli K-12 ortholog: b0007; Escherichia coli O157:H7 ortholog: z0007; transporter yaaJ complement(7147..8577) Escherichia coli CFT073 1037720 NP_751968.2 CDS talB NC_004431.1 8856 9809 D Maintains the balance of metabolites in the pentose-phosphate pathway; transaldolase B 8856..9809 Escherichia coli CFT073 1036025 NP_751969.1 CDS mogA NC_004431.1 9921 10511 D forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 9921..10511 Escherichia coli CFT073 1035942 YP_004853794.1 CDS c0014 NC_004431.1 10535 10672 R hypothetical protein complement(10535..10672) Escherichia coli CFT073 1040509 NP_751971.1 CDS yaaH NC_004431.1 10716 11282 R Escherichia coli K-12 ortholog: b0010; Escherichia coli O157:H7 ortholog: z0010; hypothetical protein complement(10716..11282) Escherichia coli CFT073 1035962 NP_751972.1 CDS yaaW NC_004431.1 11431 12144 R Escherichia coli K-12 ortholog: b0011; Escherichia coli O157:H7 ortholog: z0011; hypothetical protein complement(11431..12144) Escherichia coli CFT073 1037634 NP_751973.1 CDS yaaI NC_004431.1 12170 12574 R Escherichia coli K-12 ortholog: b0013; Escherichia coli O157:H7 ortholog: z0013; hypothetical protein complement(12170..12574) Escherichia coli CFT073 1037616 NP_751974.1 CDS c0018 NC_004431.1 12904 14940 R Residues 35 to 675 of 678 are 31.91 pct identical to residues 331 to 954 of 959 from GenPept.129 : >gb|AAG23119.1| (AF069527) glutamate dehydrogenase [Haloferax mediterranei]; glutamate dehydrogenase complement(12904..14940) Escherichia coli CFT073 1037615 NP_751975.1 CDS dnaK NC_004431.1 12946 14862 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 12946..14862 Escherichia coli CFT073 1036508 NP_751976.1 CDS dnaJ NC_004431.1 14951 16081 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 14951..16081 Escherichia coli CFT073 1037422 NP_751977.1 CDS c0021 NC_004431.1 16953 17714 D Residues 5 to 253 of 253 are 30.79 pct identical to residues 2 to 254 of 254 from MG1655 : b2408; hypothetical protein 16953..17714 Escherichia coli CFT073 1036465 NP_751978.1 CDS c0022 NC_004431.1 17698 19227 D Residues 13 to 509 of 509 are 87.92 pct identical to residues 1 to 497 of 497 from GenPept.129 : >gb|AAL18999.1| (AE008695) arylsulfatase [Salmonella typhimurium LT2]; hypothetical protein 17698..19227 Escherichia coli CFT073 1037626 NP_751979.1 CDS c0023 NC_004431.1 19356 20615 D Residues 1 to 411 of 419 are 67.15 pct identical to residues 3 to 413 of 417 from GenPept.129 : >gb|AAL19001.1| (AE008695) cytoplasmic protein [Salmonella typhimurium LT2]; hypothetical protein 19356..20615 Escherichia coli CFT073 1037604 NP_751980.1 CDS nhaA NC_004431.1 20850 22016 D exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 20850..22016 Escherichia coli CFT073 1037840 NP_751981.2 CDS nhaR NC_004431.1 22082 22981 D Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 22082..22981 Escherichia coli CFT073 1035929 NP_751982.1 CDS c0026 NC_004431.1 22948 23076 R hypothetical protein complement(22948..23076) Escherichia coli CFT073 1038106 NP_751983.1 CDS rpsT NC_004431.1 23077 23340 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(23077..23340) Escherichia coli CFT073 1035920 NP_751984.1 CDS yaaY NC_004431.1 23443 23661 D Escherichia coli K-12 ortholog: b0024; Escherichia coli O157:H7 ortholog: z0028; hypothetical protein 23443..23661 Escherichia coli CFT073 1038116 NP_751985.1 CDS ribF NC_004431.1 23669 24610 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 23669..24610 Escherichia coli CFT073 1035912 NP_751986.1 CDS ileS NC_004431.1 24653 27469 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 24653..27469 Escherichia coli CFT073 1038281 NP_751987.1 CDS lspA NC_004431.1 27469 27963 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 27469..27963 Escherichia coli CFT073 1036002 NP_751988.1 CDS slpA NC_004431.1 28071 28520 D Escherichia coli K-12 ortholog: b0028; Escherichia coli O157:H7 ortholog: z0033; FKBP-type peptidylprolyl isomerase 28071..28520 Escherichia coli CFT073 1036009 NP_751989.2 CDS ispH NC_004431.1 28522 29472 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 28522..29472 Escherichia coli CFT073 1038695 NP_751990.1 CDS c0036 NC_004431.1 30475 30840 D Residues 6 to 117 of 121 are 38.05 pct identical to residues 7 to 107 of 116 from GenPept.129 : >gb|AAF96824.1| (AE004420) conserved hypothetical protein [Vibrio cholerae]; hypothetical protein 30475..30840 Escherichia coli CFT073 1036209 NP_751991.1 CDS dapB NC_004431.1 31001 31822 D catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 31001..31822 Escherichia coli CFT073 1036149 NP_751992.1 CDS c0038 NC_004431.1 31864 32031 R hypothetical protein complement(31864..32031) Escherichia coli CFT073 1036154 NP_751993.1 CDS c0039 NC_004431.1 32101 32238 D hypothetical protein 32101..32238 Escherichia coli CFT073 1040037 NP_751994.1 CDS carA NC_004431.1 32251 33426 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 32251..33426 Escherichia coli CFT073 1038618 NP_751995.1 CDS carB NC_004431.1 33444 36665 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 33444..36665 Escherichia coli CFT073 1038143 NP_751996.1 CDS c0042 NC_004431.1 36673 36891 R Escherichia coli O157:H7 ortholog: z0039; hypothetical protein complement(36673..36891) Escherichia coli CFT073 1035994 NP_751997.2 CDS caiF NC_004431.1 36926 37321 D regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 36926..37321 Escherichia coli CFT073 1039091 NP_751998.1 CDS caiE NC_004431.1 37440 38051 R involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE complement(37440..38051) Escherichia coli CFT073 1038841 NP_751999.2 CDS caiD NC_004431.1 38036 38821 R catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase complement(38036..38821) Escherichia coli CFT073 1035947 NP_752000.1 CDS caiC NC_004431.1 38930 40498 R Escherichia coli K-12 ortholog: b0037; Escherichia coli O157:H7 ortholog: z0043; crotonobetaine/carnitine-CoA ligase complement(38930..40498) Escherichia coli CFT073 1036117 NP_752001.1 CDS caiB NC_004431.1 40556 41773 R catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase complement(40556..41773) Escherichia coli CFT073 1039569 NP_752002.1 CDS caiA NC_004431.1 41901 43043 R catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase complement(41901..43043) Escherichia coli CFT073 1035910 NP_752003.1 CDS caiT NC_004431.1 43074 44588 R catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter complement(43074..44588) Escherichia coli CFT073 1036049 NP_752004.2 CDS fixA NC_004431.1 45061 45831 D required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; electron transfer flavoprotein FixA 45061..45831 Escherichia coli CFT073 1036200 NP_752005.1 CDS fixC NC_004431.1 46809 48095 D FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; oxidoreductase FixC 46809..48095 Escherichia coli CFT073 1039636 NP_752006.1 CDS fixX NC_004431.1 48092 48379 D Escherichia coli K-12 ortholog: b0044; Escherichia coli O157:H7 ortholog: z0050; ferredoxin-like protein 48092..48379 Escherichia coli CFT073 1035905 NP_752007.1 CDS yaaU NC_004431.1 48438 49769 D Escherichia coli K-12 ortholog: b0045; Escherichia coli O157:H7 ortholog: z0051; metabolite transporter 48438..49769 Escherichia coli CFT073 1039632 NP_752008.1 CDS yabF NC_004431.1 49877 50407 D Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 49877..50407 Escherichia coli CFT073 1040497 NP_752009.1 CDS kefC NC_004431.1 50400 52262 D transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 50400..52262 Escherichia coli CFT073 1035128 NP_752010.1 CDS folA NC_004431.1 52319 52933 D catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 52319..52933 Escherichia coli CFT073 1035973 NP_752011.1 CDS c0059 NC_004431.1 53019 53252 D Escherichia coli O157:H7 ortholog: z0056; antitoxin of gyrase inhibiting toxin-antitoxin system 53019..53252 Escherichia coli CFT073 1037711 NP_752012.1 CDS c0060 NC_004431.1 53255 53569 D Escherichia coli O157:H7 ortholog: z0057; toxin of gyrase inhibiting toxin-antitoxin system 53255..53569 Escherichia coli CFT073 1034976 NP_752013.1 CDS apaH NC_004431.1 53566 54414 R hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase complement(53566..54414) Escherichia coli CFT073 1038673 NP_752014.1 CDS c0062 NC_004431.1 54385 54738 D hypothetical protein 54385..54738 Escherichia coli CFT073 1034956 NP_752015.1 CDS apaG NC_004431.1 54421 54798 R protein associated with Co2+ and Mg2+ efflux; ApaG protein complement(54421..54798) Escherichia coli CFT073 1036565 NP_752016.1 CDS ksgA NC_004431.1 54801 55622 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(54801..55622) Escherichia coli CFT073 1035880 NP_752017.1 CDS pdxA NC_004431.1 55619 56608 R catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase complement(55619..56608) Escherichia coli CFT073 1035368 NP_752018.1 CDS surA NC_004431.1 56608 57894 R Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA complement(56608..57894) Escherichia coli CFT073 1035369 NP_752019.1 CDS imp NC_004431.1 57947 60301 R determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein complement(57947..60301) Escherichia coli CFT073 1037628 NP_752020.2 CDS djlA NC_004431.1 60556 61371 D functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 60556..61371 Escherichia coli CFT073 1035622 NP_752021.1 CDS yabO NC_004431.1 61489 62148 R catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A complement(61489..62148) Escherichia coli CFT073 1040435 NP_752022.1 CDS hepA NC_004431.1 62160 65066 R transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA complement(62160..65066) Escherichia coli CFT073 1035881 NP_752023.1 CDS polB NC_004431.1 65231 67582 R Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II complement(65231..67582) Escherichia coli CFT073 1038159 NP_752024.1 CDS c0072 NC_004431.1 67723 68232 D Residues 18 to 169 of 169 are 94.07 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; transposase 67723..68232 Escherichia coli CFT073 1038698 NP_752025.1 CDS araD NC_004431.1 68369 69064 R catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase complement(68369..69064) Escherichia coli CFT073 1035252 NP_752026.1 CDS araA NC_004431.1 69349 70851 R catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase complement(69349..70851) Escherichia coli CFT073 1038173 NP_752027.1 CDS araB NC_004431.1 70862 72562 R catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase complement(70862..72562) Escherichia coli CFT073 1040445 NP_752028.1 CDS araC NC_004431.1 72901 73746 D positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; DNA-binding transcriptional regulator AraC 72901..73746 Escherichia coli CFT073 1034955 NP_752029.1 CDS c0077 NC_004431.1 74011 74133 D Residues 5 to 40 of 40 are 66.66 pct identical to residues 308 to 343 of 343 from GenPept.129 : >gb|AAL72384.1| (AF386526) hypothetical protein [Shigella flexneri 2a]; hypothetical protein 74011..74133 Escherichia coli CFT073 1035883 NP_752030.1 CDS c0078 NC_004431.1 74258 74494 D Residues 2 to 76 of 78 are 38.46 pct identical to residues 1 to 72 of 231 from GenPept.129 : >emb|CAC92308.1| (AJ414155) hypothetical protein [Yersinia pestis]; hypothetical protein 74258..74494 Escherichia coli CFT073 1035206 NP_752031.1 CDS c0079 NC_004431.1 74536 75108 D Residues 14 to 125 of 190 are 44.64 pct identical to residues 54 to 164 of 189 from GenPept.129 : >emb|CAC90441.1| (AJ414149) hypothetical protein [Yersinia pestis]; hypothetical protein 74536..75108 Escherichia coli CFT073 1035949 NP_752032.1 CDS c0080 NC_004431.1 75115 75537 D hypothetical protein 75115..75537 Escherichia coli CFT073 1036542 NP_752033.1 CDS yabI NC_004431.1 75692 76456 D Escherichia coli K-12 ortholog: b0065; Escherichia coli O157:H7 ortholog: z0074; hypothetical protein 75692..76456 Escherichia coli CFT073 1038727 NP_752034.2 CDS thiQ NC_004431.1 76570 77268 R with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit complement(76570..77268) Escherichia coli CFT073 1036401 NP_752035.1 CDS thiP NC_004431.1 77252 78862 R permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein complement(77252..78862) Escherichia coli CFT073 1035173 NP_752036.2 CDS tbpA NC_004431.1 78838 79821 R part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit complement(78838..79821) Escherichia coli CFT073 1038158 NP_752037.1 CDS yabN NC_004431.1 79985 81661 R activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR complement(79985..81661) Escherichia coli CFT073 1038194 NP_752038.1 CDS c0086 NC_004431.1 82026 82535 D Residues 18 to 169 of 169 are 95.39 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; transposase 82026..82535 Escherichia coli CFT073 1038203 NP_752039.1 CDS leuD NC_004431.1 82679 83284 R catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit complement(82679..83284) Escherichia coli CFT073 1038100 NP_752040.1 CDS c0088 NC_004431.1 82730 82915 D hypothetical protein 82730..82915 Escherichia coli CFT073 1036072 NP_752041.1 CDS leuC NC_004431.1 83295 84695 R dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit complement(83295..84695) Escherichia coli CFT073 1036454 NP_752042.2 CDS leuB NC_004431.1 84698 85789 R catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase complement(84698..85789) Escherichia coli CFT073 1036210 NP_752043.1 CDS leuA NC_004431.1 85789 87402 R catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase complement(85789..87402) Escherichia coli CFT073 1038600 NP_752044.1 CDS leuL NC_004431.1 87451 87537 R involved in attenuation control of the leuABCD operon in leucine biosynthesis; leu operon leader peptide complement(87451..87537) Escherichia coli CFT073 1036568 NP_752045.1 CDS c0092 NC_004431.1 87996 88118 D hypothetical protein 87996..88118 Escherichia coli CFT073 1038206 NP_752046.2 CDS leuO NC_004431.1 88177 89139 D activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 88177..89139 Escherichia coli CFT073 1036529 NP_752047.1 CDS c0094 NC_004431.1 89175 89303 R hypothetical protein complement(89175..89303) Escherichia coli CFT073 1038214 NP_752048.2 CDS ilvI NC_004431.1 89457 91181 D catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 89457..91181 Escherichia coli CFT073 1038215 NP_752049.2 CDS ilvH NC_004431.1 91184 91675 D with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 91184..91675 Escherichia coli CFT073 1035721 YP_004853795.1 CDS c5493 NC_004431.1 91687 91773 D hypothetical protein 91687..91773 Escherichia coli CFT073 1038230 NP_752051.1 CDS c0097 NC_004431.1 91727 91858 D hypothetical protein 91727..91858 Escherichia coli CFT073 1038226 NP_752052.1 CDS fruR NC_004431.1 91855 92859 D binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 91855..92859 Escherichia coli CFT073 1035886 NP_752053.1 CDS yabB NC_004431.1 93425 93919 D MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 93425..93919 Escherichia coli CFT073 1035671 NP_752054.1 CDS mraW NC_004431.1 93921 94862 D Escherichia coli K-12 ortholog: b0082; Escherichia coli O157:H7 ortholog: z0092; S-adenosyl-methyltransferase MraW 93921..94862 Escherichia coli CFT073 1038217 NP_752055.1 CDS ftsL NC_004431.1 94859 95224 D membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 94859..95224 Escherichia coli CFT073 1038220 NP_752056.1 CDS ftsI NC_004431.1 95240 97006 D Penicillin-binding protein 3; Escherichia coli K-12 ortholog: b0084; Escherichia coli O157:H7 ortholog: z0094; peptidoglycan synthetase ftsI 95240..97006 Escherichia coli CFT073 1040459 NP_752057.1 CDS murE NC_004431.1 96993 98480 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 96993..98480 Escherichia coli CFT073 1035233 NP_752058.1 CDS murF NC_004431.1 98477 99835 D Escherichia coli K-12 ortholog: b0086; Escherichia coli O157:H7 ortholog: z0096; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 98477..99835 Escherichia coli CFT073 1035941 NP_752059.1 CDS mraY NC_004431.1 99829 100911 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 99829..100911 Escherichia coli CFT073 1035664 NP_752060.1 CDS murD NC_004431.1 100914 102230 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 100914..102230 Escherichia coli CFT073 1038341 NP_752061.1 CDS ftsW NC_004431.1 102227 103474 D integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 102227..103474 Escherichia coli CFT073 1035981 NP_752062.1 CDS murG NC_004431.1 103471 104538 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 103471..104538 Escherichia coli CFT073 1036005 NP_752063.1 CDS murC NC_004431.1 104592 106067 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 104592..106067 Escherichia coli CFT073 1038105 NP_752064.1 CDS ddl NC_004431.1 106060 106980 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 106060..106980 Escherichia coli CFT073 1038266 NP_752065.1 CDS ftsQ NC_004431.1 106982 107812 D involved in septum formation; cell division protein FtsQ 106982..107812 Escherichia coli CFT073 1035662 NP_752066.1 CDS ftsA NC_004431.1 107809 109071 D ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 107809..109071 Escherichia coli CFT073 1038103 NP_752067.1 CDS ftsZ NC_004431.1 109132 110283 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 109132..110283 Escherichia coli CFT073 1035944 NP_752068.1 CDS lpxC NC_004431.1 110384 111301 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 110384..111301 Escherichia coli CFT073 1037189 NP_752069.2 CDS yacA NC_004431.1 111532 112044 D secM translational pause allows for the initiation of secA translation; SecA regulator SecM 111532..112044 Escherichia coli CFT073 1037447 NP_752070.1 CDS secA NC_004431.1 112106 114811 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 112106..114811 Escherichia coli CFT073 1035616 NP_752071.1 CDS mutT NC_004431.1 114871 115269 D 7,8-dihydro-8-oxoguanine-triphosphatase; Escherichia coli K-12 ortholog: b0099; Escherichia coli O157:H7 ortholog: z0109; nucleoside triphosphate pyrophosphohydrolase 114871..115269 Escherichia coli CFT073 1038581 NP_752072.1 CDS c0118 NC_004431.1 115372 115893 D Residues 1 to 173 of 173 are 99.42 pct identical to residues 1 to 173 of 173 from SwissProt.40 : >sp|Q47309|YI9A_ECOLI INSERTION ELEMENT IS1397 HYPOTHETICAL 20.1 KD PROTEIN (ORFA); hypothetical protein 115372..115893 Escherichia coli CFT073 1035330 NP_752073.1 CDS c0119 NC_004431.1 115993 116715 D Escherichia coli K-12 ortholog: b3558; transposase insK 115993..116715 Escherichia coli CFT073 1038102 NP_752074.1 CDS c0120 NC_004431.1 116785 116982 D hypothetical protein 116785..116982 Escherichia coli CFT073 1035000 NP_752075.1 CDS yacG NC_004431.1 116788 116985 R Escherichia coli K-12 ortholog: b0101; Escherichia coli O157:H7 ortholog: z0111; zinc-binding protein complement(116788..116985) Escherichia coli CFT073 1035890 NP_752076.1 CDS yacF NC_004431.1 116995 117738 R Escherichia coli K-12 ortholog: b0102; Escherichia coli O157:H7 ortholog: z0112; hypothetical protein complement(116995..117738) Escherichia coli CFT073 1035891 NP_752077.1 CDS coaE NC_004431.1 117738 118358 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(117738..118358) Escherichia coli CFT073 1039004 NP_752078.1 CDS guaC NC_004431.1 118583 119626 D catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 118583..119626 Escherichia coli CFT073 1037488 NP_752079.1 CDS hofC NC_004431.1 119661 120863 R Escherichia coli K-12 ortholog: b0106; Escherichia coli O157:H7 ortholog: z0116; type IV pilin biogenesis protein complement(119661..120863) Escherichia coli CFT073 1035893 NP_752080.1 CDS hofB NC_004431.1 120853 122238 R Escherichia coli K-12 ortholog: b0107; Escherichia coli O157:H7 ortholog: z0117; hypothetical protein complement(120853..122238) Escherichia coli CFT073 1038132 NP_752081.1 CDS ppdD NC_004431.1 122248 122688 R Escherichia coli K-12 ortholog: b0108; Escherichia coli O157:H7 ortholog: z0118; major pilin subunit complement(122248..122688) Escherichia coli CFT073 1038736 NP_752082.2 CDS nadC NC_004431.1 122892 123785 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase complement(122892..123785) Escherichia coli CFT073 1036374 NP_752083.1 CDS ampD NC_004431.1 123873 124424 D Escherichia coli K-12 ortholog: b0110; Escherichia coli O157:H7 ortholog: z0120; N-acetyl-anhydromuranmyl-L-alanine amidase 123873..124424 Escherichia coli CFT073 1036599 NP_752084.1 CDS ampE NC_004431.1 124421 125275 D involved in regulation of beta-lactamase; signaling protein; regulatory protein AmpE 124421..125275 Escherichia coli CFT073 1036494 NP_752085.1 CDS aroP NC_004431.1 125318 126688 R General aromatic amino acid permease; Escherichia coli K-12 ortholog: b0112; Escherichia coli O157:H7 ortholog: z0122; aromatic amino acid transporter complement(125318..126688) Escherichia coli CFT073 1036490 NP_752086.1 CDS c0133 NC_004431.1 128997 129293 D Residues 5 to 95 of 98 are 45.16 pct identical to residues 2 to 85 of 87 from SwissProt.40 : >sp|Q03708|IMM7_ECOLI COLICIN E7 IMMUNITY PROTEIN (IMME7) (MICROCIN E7 IMMUNITY PROTEIN); hypothetical protein 128997..129293 Escherichia coli CFT073 1036502 NP_752087.1 CDS c0134 NC_004431.1 129267 129410 R hypothetical protein complement(129267..129410) Escherichia coli CFT073 1036484 NP_752088.1 CDS c0136 NC_004431.1 129968 130090 R hypothetical protein complement(129968..130090) Escherichia coli CFT073 1036341 NP_752089.1 CDS c0137 NC_004431.1 130380 130670 D Residues 5 to 93 of 96 are 46.06 pct identical to residues 4 to 85 of 87 from SwissProt.40 : >sp|Q03708|IMM7_ECOLI COLICIN E7 IMMUNITY PROTEIN (IMME7) (MICROCIN E7 IMMUNITY PROTEIN); hypothetical protein 130380..130670 Escherichia coli CFT073 1036552 NP_752090.1 CDS c0138 NC_004431.1 131044 131370 D Escherichia coli O157:H7 ortholog: z2982; hypothetical protein 131044..131370 Escherichia coli CFT073 1036081 NP_752091.1 CDS c0139 NC_004431.1 131367 132257 D Escherichia coli O157:H7 ortholog: z3297; transposase IS629 131367..132257 Escherichia coli CFT073 1035861 NP_752092.2 CDS pdhR NC_004431.1 132439 133203 D activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 132439..133203 Escherichia coli CFT073 1036476 NP_752093.1 CDS c0141 NC_004431.1 133200 133382 R hypothetical protein complement(133200..133382) Escherichia coli CFT073 1035906 NP_752094.1 CDS aceE NC_004431.1 133364 136027 D E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 133364..136027 Escherichia coli CFT073 1040471 NP_752095.2 CDS lpdA NC_004431.1 138143 139567 D E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 138143..139567 Escherichia coli CFT073 1037753 NP_752096.1 CDS yacH NC_004431.1 139809 141590 R Escherichia coli K-12 ortholog: b0117; Escherichia coli O157:H7 ortholog: z0127; hypothetical protein complement(139809..141590) Escherichia coli CFT073 1040499 NP_752097.2 CDS acnB NC_004431.1 141945 144542 D catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 141945..144542 Escherichia coli CFT073 1036517 NP_752098.2 CDS yacL NC_004431.1 144717 145079 D Escherichia coli K-12 ortholog: b0119; Escherichia coli O157:H7 ortholog: z0129; hypothetical protein 144717..145079 Escherichia coli CFT073 1035678 NP_752099.1 CDS speD NC_004431.1 145117 145911 R S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase complement(145117..145911) Escherichia coli CFT073 1037308 NP_752100.1 CDS speE NC_004431.1 145927 146793 R catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase complement(145927..146793) Escherichia coli CFT073 1040054 NP_752101.1 CDS yacC NC_004431.1 146899 147417 R Escherichia coli K-12 ortholog: b0122; Escherichia coli O157:H7 ortholog: z0132; hypothetical protein complement(146899..147417) Escherichia coli CFT073 1039884 NP_752102.2 CDS yacK NC_004431.1 147412 148962 D laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 147412..148962 Escherichia coli CFT073 1040023 NP_752103.1 CDS gcd NC_004431.1 149040 151448 R Pyrroloquinoline-quinone; Escherichia coli K-12 ortholog: b0124; Escherichia coli O157:H7 ortholog: z0134; glucose dehydrogenase complement(149040..151448) Escherichia coli CFT073 1037173 NP_752104.2 CDS hpt NC_004431.1 151636 152172 D Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; hypoxanthine-guanine phosphoribosyltransferase 151636..152172 Escherichia coli CFT073 1040065 NP_752105.1 CDS yadF NC_004431.1 152213 152875 R catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase complement(152213..152875) Escherichia coli CFT073 1037331 NP_752106.1 CDS yadG NC_004431.1 152984 153910 D Escherichia coli K-12 ortholog: b0127; Escherichia coli O157:H7 ortholog: z0138; ABC transporter ATP-binding protein 152984..153910 Escherichia coli CFT073 1035410 NP_752107.1 CDS yadH NC_004431.1 153907 154677 D Escherichia coli K-12 ortholog: b0128; Escherichia coli O157:H7 ortholog: z0139; hypothetical protein 153907..154677 Escherichia coli CFT073 1035963 NP_752108.1 CDS yadI NC_004431.1 154782 155222 D Escherichia coli K-12 ortholog: b0129; Escherichia coli O157:H7 ortholog: z0140; PTS system IIA component yadI 154782..155222 Escherichia coli CFT073 1038099 NP_752109.1 CDS yadE NC_004431.1 155286 156515 D Escherichia coli K-12 ortholog: b0130; Escherichia coli O157:H7 ortholog: z0141; hypothetical protein 155286..156515 Escherichia coli CFT073 1036680 NP_752110.1 CDS panD NC_004431.1 156519 156899 R Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase complement(156519..156899) Escherichia coli CFT073 1037618 NP_752111.1 CDS c0161 NC_004431.1 156867 157052 D hypothetical protein 156867..157052 Escherichia coli CFT073 1040423 NP_752112.1 CDS yadD NC_004431.1 157173 158117 D Escherichia coli K-12 ortholog: b0132; Escherichia coli O157:H7 ortholog: z0143; hypothetical protein 157173..158117 Escherichia coli CFT073 1035964 NP_752113.1 CDS c0163 NC_004431.1 158186 158383 D Residues 4 to 63 of 65 are 68.75 pct identical to residues 235 to 298 of 298 from GenPept.129 : >gb|AAG54436.1|AE005189_9 (AE005189) orf, hypothetical protein [Escherichia coli O157:H7 EDL933]; hypothetical protein 158186..158383 Escherichia coli CFT073 1039167 NP_752114.1 CDS panC NC_004431.1 158465 159238 R catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase complement(158465..159238) Escherichia coli CFT073 1039422 NP_752115.1 CDS panB NC_004431.1 159329 160123 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(159329..160123) Escherichia coli CFT073 1036661 NP_752116.1 CDS yadC NC_004431.1 160235 161524 R Escherichia coli K-12 ortholog: b0135; fimbrial-like adhesin protein complement(160235..161524) Escherichia coli CFT073 1036698 NP_752117.1 CDS yadK NC_004431.1 161550 162146 R Escherichia coli K-12 ortholog: b0136; hypothetical protein complement(161550..162146) Escherichia coli CFT073 1039659 NP_752118.1 CDS yadL NC_004431.1 162173 162787 R Escherichia coli K-12 ortholog: b0137; Escherichia coli O157:H7 ortholog: z0148; hypothetical protein complement(162173..162787) Escherichia coli CFT073 1039625 NP_752119.1 CDS yadM NC_004431.1 162793 163359 R Escherichia coli K-12 ortholog: b0138; Escherichia coli O157:H7 ortholog: z0149; hypothetical protein complement(162793..163359) Escherichia coli CFT073 1039623 NP_752120.1 CDS htrE NC_004431.1 163376 165964 R similar to the fimbrial usher protein PapC; outer membrane usher protein complement(163376..165964) Escherichia coli CFT073 1039139 NP_752121.1 CDS ecpD NC_004431.1 165999 166739 R Escherichia coli K-12 ortholog: b0140; Escherichia coli O157:H7 ortholog: z0151; chaperone protein EcpD complement(165999..166739) Escherichia coli CFT073 1037625 NP_752122.1 CDS yadN NC_004431.1 166848 167462 R Escherichia coli K-12 ortholog: b0141; Escherichia coli O157:H7 ortholog: z0152; fimbrial-like protein yadN complement(166848..167462) Escherichia coli CFT073 1038086 NP_752123.1 CDS c0173 NC_004431.1 167431 167571 R hypothetical protein complement(167431..167571) Escherichia coli CFT073 1035277 NP_752124.1 CDS c0174 NC_004431.1 167479 167607 D hypothetical protein 167479..167607 Escherichia coli CFT073 1040426 NP_752125.1 CDS folK NC_004431.1 167802 168281 R catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase complement(167802..168281) Escherichia coli CFT073 1039898 NP_752126.1 CDS pcnB NC_004431.1 168278 169696 R Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase complement(168278..169696) Escherichia coli CFT073 1037253 NP_752127.2 CDS yadB NC_004431.1 169735 170631 R this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase complement(169735..170631) Escherichia coli CFT073 1038583 NP_752128.2 CDS dksA NC_004431.1 170698 171153 R Escherichia coli K-12 ortholog: b0145; Escherichia coli O157:H7 ortholog: z0156; RNA polymerase-binding transcription factor complement(170698..171153) Escherichia coli CFT073 1038134 NP_752129.1 CDS sfsA NC_004431.1 171331 172035 R Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A complement(171331..172035) Escherichia coli CFT073 1039832 NP_752130.1 CDS yadP NC_004431.1 172050 172589 R Escherichia coli K-12 ortholog: b0147; Escherichia coli O157:H7 ortholog: z0158; 2'-5' RNA ligase complement(172050..172589) Escherichia coli CFT073 1039113 NP_752131.1 CDS hrpB NC_004431.1 172609 175083 D similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 172609..175083 Escherichia coli CFT073 1037155 NP_752132.1 CDS c0182 NC_004431.1 175011 175178 R hypothetical protein complement(175011..175178) Escherichia coli CFT073 1040478 NP_752133.1 CDS mrcB NC_004431.1 175177 177711 D bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 175177..177711 Escherichia coli CFT073 1040454 NP_752134.1 CDS c0184 NC_004431.1 177776 177958 R hypothetical protein complement(177776..177958) Escherichia coli CFT073 1040468 NP_752135.1 CDS fhuA NC_004431.1 177931 180189 D involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 177931..180189 Escherichia coli CFT073 1035322 NP_752136.2 CDS fhuC NC_004431.1 180240 181037 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 180240..181037 Escherichia coli CFT073 1038423 NP_752137.1 CDS fhuD NC_004431.1 181034 181927 D Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 181034..181927 Escherichia coli CFT073 1035877 NP_752138.1 CDS fhuB NC_004431.1 181924 183906 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 181924..183906 Escherichia coli CFT073 1038971 NP_752139.1 CDS hemL NC_004431.1 183941 185221 R Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase complement(183941..185221) Escherichia coli CFT073 1035152 NP_752140.1 CDS yadQ NC_004431.1 185446 186867 D Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 185446..186867 Escherichia coli CFT073 1037702 NP_752141.1 CDS yadR NC_004431.1 186916 187293 D essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 186916..187293 Escherichia coli CFT073 1035141 NP_752142.1 CDS c0192 NC_004431.1 187045 187305 R hypothetical protein complement(187045..187305) Escherichia coli CFT073 1035863 NP_752143.1 CDS yadS NC_004431.1 187340 187963 R Escherichia coli K-12 ortholog: b0157; Escherichia coli O157:H7 ortholog: z0168; hypothetical protein complement(187340..187963) Escherichia coli CFT073 1035163 NP_752144.1 CDS yadT NC_004431.1 188001 188801 R solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF complement(188001..188801) Escherichia coli CFT073 1038962 NP_752145.1 CDS pfs NC_004431.1 188794 189492 R enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase complement(188794..189492) Escherichia coli CFT073 1035162 NP_752146.1 CDS dgt NC_004431.1 189576 191093 D forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 189576..191093 Escherichia coli CFT073 1038164 NP_752147.1 CDS htrA NC_004431.1 191223 192647 D protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 191223..192647 Escherichia coli CFT073 1035843 NP_752148.1 CDS c0198 NC_004431.1 192782 193291 D Residues 18 to 169 of 169 are 95.39 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; transposase 192782..193291 Escherichia coli CFT073 1035272 NP_752149.2 CDS yaeG NC_004431.1 193513 194670 D regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 193513..194670 Escherichia coli CFT073 1035191 NP_752150.1 CDS yaeH NC_004431.1 194723 195109 R Escherichia coli K-12 ortholog: b0163; Escherichia coli O157:H7 ortholog: z0175; hypothetical protein complement(194723..195109) Escherichia coli CFT073 1039053 NP_752151.1 CDS dapD NC_004431.1 195421 196245 R catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase complement(195421..196245) Escherichia coli CFT073 1037369 NP_752152.1 CDS glnD NC_004431.1 196276 198948 R catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase complement(196276..198948) Escherichia coli CFT073 1035903 NP_752153.1 CDS map NC_004431.1 199010 199804 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase complement(199010..199804) Escherichia coli CFT073 1035347 NP_752154.2 CDS rpsB NC_004431.1 200172 200897 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 200172..200897 Escherichia coli CFT073 1036400 NP_752155.1 CDS c0205 NC_004431.1 200849 201778 R hypothetical protein complement(200849..201778) Escherichia coli CFT073 1037643 NP_752156.1 CDS tsf NC_004431.1 201032 201883 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 201032..201883 Escherichia coli CFT073 1039042 NP_752157.1 CDS pyrH NC_004431.1 202030 202755 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 202030..202755 Escherichia coli CFT073 1040461 NP_752158.1 CDS frr NC_004431.1 202905 203462 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 202905..203462 Escherichia coli CFT073 1035876 NP_752159.1 CDS yaeS NC_004431.1 204938 205699 D catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 204938..205699 Escherichia coli CFT073 1035882 NP_752160.1 CDS cdsA NC_004431.1 205712 206569 D catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 205712..206569 Escherichia coli CFT073 1035795 NP_752161.1 CDS yaeL NC_004431.1 206536 207933 D catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 206536..207933 Escherichia coli CFT073 1035797 NP_752162.1 CDS yaeT NC_004431.1 207963 210395 D part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 207963..210395 Escherichia coli CFT073 1038708 NP_752163.1 CDS hlpA NC_004431.1 210517 211002 D DNA-binding 17 kDa protein; Escherichia coli K-12 ortholog: b0178; Escherichia coli O157:H7 ortholog: z0190; periplasmic chaperone 210517..211002 Escherichia coli CFT073 1035875 NP_752164.1 CDS lpxD NC_004431.1 211006 212031 D adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 211006..212031 Escherichia coli CFT073 1035816 NP_752165.1 CDS fabZ NC_004431.1 212043 212591 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 212043..212591 Escherichia coli CFT073 1037553 NP_752166.1 CDS lpxA NC_004431.1 212595 213383 D catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 212595..213383 Escherichia coli CFT073 1039054 NP_752167.1 CDS lpxB NC_004431.1 213383 214531 D catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 213383..214531 Escherichia coli CFT073 1035825 NP_752168.1 CDS rnhB NC_004431.1 214528 215124 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 214528..215124 Escherichia coli CFT073 1035867 NP_752169.1 CDS dnaE NC_004431.1 215161 218643 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 215161..218643 Escherichia coli CFT073 1038041 NP_752170.1 CDS c0222 NC_004431.1 218587 219522 R hypothetical protein complement(218587..219522) Escherichia coli CFT073 1035778 NP_752171.1 CDS accA NC_004431.1 218656 219615 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 218656..219615 Escherichia coli CFT073 1035804 NP_752172.1 CDS ldcC NC_004431.1 219713 221854 D Escherichia coli K-12 ortholog: b0186; Escherichia coli O157:H7 ortholog: z0198; lysine decarboxylase, constitutive 219713..221854 Escherichia coli CFT073 1039108 NP_752173.2 CDS yaeR NC_004431.1 221911 222300 D Escherichia coli K-12 ortholog: b0187; Escherichia coli O157:H7 ortholog: z0199; hypothetical protein 221911..222300 Escherichia coli CFT073 1035895 NP_752174.1 CDS tilS NC_004431.1 222365 223678 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 222365..223678 Escherichia coli CFT073 1035896 NP_752175.1 CDS yaeO NC_004431.1 223712 223972 R Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator complement(223712..223972) Escherichia coli CFT073 1040430 NP_752176.1 CDS c0228 NC_004431.1 223959 224159 R Residues 1 to 66 of 66 are 98.48 pct identical to residues 1 to 66 of 66 from SwissProt.40 : >sp|P52099|YAEP_ECOLI Hypothetical protein yaeP; hypothetical protein complement(223959..224159) Escherichia coli CFT073 1036145 NP_752177.1 CDS yaeQ NC_004431.1 224325 224870 D Escherichia coli K-12 ortholog: b0190; Escherichia coli O157:H7 ortholog: z0202; hypothetical protein 224325..224870 Escherichia coli CFT073 1035958 NP_752178.1 CDS yaeJ NC_004431.1 224867 225289 D Escherichia coli K-12 ortholog: b0191; Escherichia coli O157:H7 ortholog: z0203; peptidyl-tRNA hydrolase domain protein 224867..225289 Escherichia coli CFT073 1039631 NP_752179.1 CDS cutF NC_004431.1 225303 226013 D Lipoprotein nlpE; Escherichia coli K-12 ortholog: b0192; Escherichia coli O157:H7 ortholog: z0204; lipoprotein involved with copper homeostasis and adhesion 225303..226013 Escherichia coli CFT073 1035184 NP_752180.1 CDS c0232 NC_004431.1 226161 226883 R Escherichia coli K-12 ortholog: b3558; transposase insK complement(226161..226883) Escherichia coli CFT073 1037489 NP_752181.1 CDS c0233 NC_004431.1 226983 227513 R Residues 4 to 176 of 176 are 99.42 pct identical to residues 1 to 173 of 173 from SwissProt.40 : >sp|Q47309|YI9A_ECOLI INSERTION ELEMENT IS1397 HYPOTHETICAL 20.1 KD PROTEIN (ORFA); hypothetical protein complement(226983..227513) Escherichia coli CFT073 1036589 NP_752182.2 CDS yaeF NC_004431.1 227599 228423 R Escherichia coli K-12 ortholog: b0193; Escherichia coli O157:H7 ortholog: z0205; hypothetical protein complement(227599..228423) Escherichia coli CFT073 1038507 NP_752183.2 CDS proS NC_004431.1 228476 230194 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(228476..230194) Escherichia coli CFT073 1037637 NP_752184.1 CDS yaeB NC_004431.1 230305 231012 R Escherichia coli K-12 ortholog: b0195; Escherichia coli O157:H7 ortholog: z0207; hypothetical protein complement(230305..231012) Escherichia coli CFT073 1036674 NP_752185.1 CDS rcsF NC_004431.1 231009 231413 R Escherichia coli K-12 ortholog: b0196; Escherichia coli O157:H7 ortholog: z0208; outer membrane lipoprotein complement(231009..231413) Escherichia coli CFT073 1040431 NP_752186.1 CDS metQ NC_004431.1 231531 232343 R Escherichia coli K-12 ortholog: b0197; Escherichia coli O157:H7 ortholog: z0209; DL-methionine transporter substrate-binding subunit complement(231531..232343) Escherichia coli CFT073 1035167 NP_752187.1 CDS yaeE NC_004431.1 232383 233036 R part of the MetNIQ methionine uptake system; DL-methionine transporter permease subunit complement(232383..233036) Escherichia coli CFT073 1039647 NP_752188.1 CDS metN NC_004431.1 233029 234060 R part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit complement(233029..234060) Escherichia coli CFT073 1039648 NP_752189.1 CDS yaeD NC_004431.1 234248 234820 D Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 234248..234820 Escherichia coli CFT073 1040234 NP_752190.1 CDS dkgB NC_004431.1 240568 241371 D catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 240568..241371 Escherichia coli CFT073 1035470 NP_752191.1 CDS yafC NC_004431.1 241368 242282 R Escherichia coli K-12 ortholog: b0208; Escherichia coli O157:H7 ortholog: z0230; transcriptional regulator YafC complement(241368..242282) Escherichia coli CFT073 1035687 NP_752192.1 CDS yafD NC_004431.1 242499 243323 D Escherichia coli K-12 ortholog: b0209; Escherichia coli O157:H7 ortholog: z0232; hypothetical protein 242499..243323 Escherichia coli CFT073 1036014 NP_752193.1 CDS yafE NC_004431.1 243401 244171 D Escherichia coli K-12 ortholog: b0210; Escherichia coli O157:H7 ortholog: z0233; hypothetical protein 243401..244171 Escherichia coli CFT073 1035838 NP_752194.1 CDS mltD NC_004431.1 244220 245578 R catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D complement(244220..245578) Escherichia coli CFT073 1036039 NP_752195.1 CDS gloB NC_004431.1 245650 246405 R catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase complement(245650..246405) Escherichia coli CFT073 1040410 NP_752196.1 CDS yafS NC_004431.1 246421 247161 D Escherichia coli K-12 ortholog: b0213; Escherichia coli O157:H7 ortholog: z0237; hypothetical protein 246421..247161 Escherichia coli CFT073 1039521 NP_752197.2 CDS rnhA NC_004431.1 247158 247625 R An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H complement(247158..247625) Escherichia coli CFT073 1036861 NP_752198.1 CDS dnaQ NC_004431.1 247681 248421 D 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 247681..248421 Escherichia coli CFT073 1035245 NP_752199.1 CDS c0253 NC_004431.1 248670 249014 D hypothetical protein 248670..249014 Escherichia coli CFT073 1038034 NP_752200.1 CDS c0254 NC_004431.1 248751 248996 R Residues 1 to 75 of 81 are 53.33 pct identical to residues 205 to 279 of 280 from GenPept.129 : >gb|AAL57572.1|AF453442_1 (AF453442) unknown [Escherichia coli]; hypothetical protein complement(248751..248996) Escherichia coli CFT073 1036564 NP_752201.1 CDS c0255 NC_004431.1 249162 249608 R Residues 1 to 148 of 148 are 70.94 pct identical to residues 1 to 148 of 174 from GenPept.129 : >gb|AAL67385.1|AF447814_53 (AF447814) L0010-like protein [Escherichia coli]; hypothetical protein complement(249162..249608) Escherichia coli CFT073 1040495 NP_752202.1 CDS c0256 NC_004431.1 249923 250144 D Residues 7 to 69 of 73 are 66.66 pct identical to residues 5 to 67 of 141 from GenPept.129 : >gb|AAG55763.1|AE005312_9 (AE005312) unknown in ISEc8 [Escherichia coli O157:H7 EDL933]; hypothetical protein 249923..250144 Escherichia coli CFT073 1039592 NP_752203.1 CDS c0257 NC_004431.1 250214 250564 D Escherichia coli O157:H7 ortholog: z1599; hypothetical protein 250214..250564 Escherichia coli CFT073 1036555 NP_752204.1 CDS c0258 NC_004431.1 250595 251242 D Residues 1 to 215 of 215 are 100.00 pct identical to residues 10 to 224 of 224 from GenPept.129 : >gb|AAL67334.1|AF447814_2 (AF447814) L0015-like protein [Escherichia coli]; hypothetical protein 250595..251242 Escherichia coli CFT073 1036558 NP_752205.1 CDS c0259 NC_004431.1 251193 252143 D Residues 42 to 316 of 316 are 100.00 pct identical to residues 1 to 275 of 275 from GenPept.129 : >gb|AAL67335.1|AF447814_3 (AF447814) L0015-like protein [Escherichia coli]; hypothetical protein 251193..252143 Escherichia coli CFT073 1036557 NP_752206.1 CDS c0260 NC_004431.1 251502 251666 R hypothetical protein complement(251502..251666) Escherichia coli CFT073 1036549 NP_752207.1 CDS c0261 NC_004431.1 252253 253386 R Residues 8 to 372 of 377 are 47.26 pct identical to residues 39 to 390 of 390 from SwissProt.40 : >sp|P55626|Y4QE_RHISN TRANSPOSASE Y4QE; hypothetical protein complement(252253..253386) Escherichia coli CFT073 1036553 NP_752208.1 CDS c0262 NC_004431.1 253450 253635 D Residues 1 to 61 of 61 are 100.00 pct identical to residues 477 to 537 of 537 from GenPept.129 : >gb|AAG55715.1|AE005309_5 (AE005309) unknown in ISEc8 [Escherichia coli O157:H7 EDL933]; hypothetical protein 253450..253635 Escherichia coli CFT073 1036551 NP_752209.1 CDS c0263 NC_004431.1 253783 254469 D Escherichia coli O157:H7 ortholog: z4330; transposase 253783..254469 Escherichia coli CFT073 1036546 NP_752210.1 CDS c0264 NC_004431.1 254517 254771 D Residues 1 to 84 of 84 are 97.61 pct identical to residues 260 to 343 of 343 from GenPept.129 : >emb|CAA29389.1| (X05955) ORF (343 AA) [Shigella sonnei]; hypothetical protein 254517..254771 Escherichia coli CFT073 1036545 NP_752211.1 CDS c0265 NC_004431.1 254850 255197 R Residues 1 to 115 of 115 are 100.00 pct identical to residues 1 to 115 of 115 from GenPept.129 : >gb|AAL67339.1|AF447814_7 (AF447814) L0008-like protein [Escherichia coli]; hypothetical protein complement(254850..255197) Escherichia coli CFT073 1036541 NP_752212.1 CDS c0268 NC_004431.1 256927 257682 D Residues 1 to 244 of 251 are 41.60 pct identical to residues 1 to 250 of 298 from SwissProt.40 : >sp|P55500|Y4IQ_RHISN INSERTION SEQUENCE ATP-BINDING PROTEIN Y4IQ/Y4ND/Y4SD; hypothetical protein 256927..257682 Escherichia coli CFT073 1036538 NP_752213.1 CDS c0269 NC_004431.1 257757 258134 R Escherichia coli K-12 ortholog: b2005; Escherichia coli O157:H7 ortholog: z5091; hypothetical protein complement(257757..258134) Escherichia coli CFT073 1036534 NP_752214.1 CDS c0270 NC_004431.1 258181 258645 R Escherichia coli K-12 ortholog: b2004; Escherichia coli O157:H7 ortholog: z1658; hypothetical protein complement(258181..258645) Escherichia coli CFT073 1036531 NP_752215.1 CDS c0271 NC_004431.1 258605 259249 R Residues 178 to 214 of 214 are 72.97 pct identical to residues 1 to 37 of 37 from GenPept.129 : >gb|AAL57577.1|AF453442_6 (AF453442) unknown [Escherichia coli]; hypothetical protein complement(258605..259249) Escherichia coli CFT073 1036533 NP_752216.1 CDS c0272 NC_004431.1 259268 259489 R Escherichia coli K-12 ortholog: b2003; Escherichia coli O157:H7 ortholog: z1218; hypothetical protein complement(259268..259489) Escherichia coli CFT073 1036528 NP_752217.1 CDS c0273 NC_004431.1 259552 260043 R Escherichia coli K-12 ortholog: b2002; Escherichia coli O157:H7 ortholog: z1217; radC-like protein yeeS complement(259552..260043) Escherichia coli CFT073 1036498 NP_752218.1 CDS c0274 NC_004431.1 259564 260523 D Residues 1 to 319 of 319 are 100.00 pct identical to residues 1 to 319 of 319 from GenPept.129 : >gb|AAL67347.1|AF447814_15 (AF447814) unknown [Escherichia coli]; hypothetical protein 259564..260523 Escherichia coli CFT073 1036520 NP_752219.1 CDS c0275 NC_004431.1 260044 260589 R Escherichia coli K-12 ortholog: b0248; Escherichia coli O157:H7 ortholog: z1656; hypothetical protein complement(260044..260589) Escherichia coli CFT073 1036519 NP_752220.1 CDS c0276 NC_004431.1 260611 260835 R Residues 1 to 45 of 74 are 97.77 pct identical to residues 8 to 52 of 271 from GenPept.129 : >gb|AAK00478.1| (AF200692) unknown [Shigella flexneri 2a]; hypothetical protein complement(260611..260835) Escherichia coli CFT073 1036513 NP_752221.1 CDS c0277 NC_004431.1 260823 261671 D Residues 90 to 282 of 282 are 100.00 pct identical to residues 1 to 193 of 193 from GenPept.129 : >gb|AAL67348.1|AF447814_16 (AF447814) unknown [Escherichia coli]; hypothetical protein 260823..261671 Escherichia coli CFT073 1036518 NP_752222.1 CDS c0278 NC_004431.1 260856 261677 R Escherichia coli K-12 ortholog: b0252; Escherichia coli O157:H7 ortholog: z1655; hypothetical protein complement(260856..261677) Escherichia coli CFT073 1036516 NP_752223.1 CDS c0279 NC_004431.1 261777 262010 R Escherichia coli K-12 ortholog: b0249; hypothetical protein complement(261777..262010) Escherichia coli CFT073 1036505 NP_752224.1 CDS c0280 NC_004431.1 262128 262613 R Residues 12 to 161 of 161 are 100.00 pct identical to residues 1 to 150 of 150 from GenPept.129 : >gb|AAL67352.1|AF447814_20 (AF447814) unknown [Escherichia coli]; hypothetical protein complement(262128..262613) Escherichia coli CFT073 1036514 NP_752225.1 CDS c0281 NC_004431.1 262736 262984 R Residues 1 to 82 of 82 are 100.00 pct identical to residues 1 to 82 of 82 from GenPept.129 : >gb|AAL67353.1|AF447814_21 (AF447814) unknown [Escherichia coli]; hypothetical protein complement(262736..262984) Escherichia coli CFT073 1040256 NP_752226.1 CDS c0282 NC_004431.1 263015 263653 R Residues 4 to 212 of 212 are 100.00 pct identical to residues 1 to 209 of 209 from GenPept.129 : >gb|AAL67354.1|AF447814_22 (AF447814) unknown [Escherichia coli]; hypothetical protein complement(263015..263653) Escherichia coli CFT073 1036506 NP_752227.1 CDS c0283 NC_004431.1 263700 264206 R Residues 1 to 168 of 168 are 100.00 pct identical to residues 1 to 168 of 168 from GenPept.129 : >gb|AAL67355.1|AF447814_23 (AF447814) intergenic-region protein [Escherichia coli]; hypothetical protein complement(263700..264206) Escherichia coli CFT073 1036503 NP_752228.1 CDS c0284 NC_004431.1 264296 265366 R Escherichia coli O157:H7 ortholog: z1654; hypothetical protein complement(264296..265366) Escherichia coli CFT073 1036491 NP_752229.1 CDS c0285 NC_004431.1 265363 266268 R Escherichia coli O157:H7 ortholog: z1653; hypothetical protein complement(265363..266268) Escherichia coli CFT073 1040035 NP_752230.1 CDS c0286 NC_004431.1 266265 268076 R Escherichia coli O157:H7 ortholog: z1652; hypothetical protein complement(266265..268076) Escherichia coli CFT073 1036499 NP_752231.1 CDS c0287 NC_004431.1 268315 268662 R Residues 1 to 108 of 115 are 97.22 pct identical to residues 2 to 109 of 795 from GenPept.129 : >gb|AAG55767.1|AE005313_2 (AE005313) unknown [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(268315..268662) Escherichia coli CFT073 1036486 NP_752232.1 CDS c0288 NC_004431.1 268880 269005 R Residues 1 to 41 of 41 are 97.56 pct identical to residues 63 to 103 of 103 from GenPept.129 : >gb|AAL67360.1|AF447814_28 (AF447814) unknown [Escherichia coli]; hypothetical protein complement(268880..269005) Escherichia coli CFT073 1039658 NP_752233.1 CDS c0289 NC_004431.1 269022 269378 R Residues 22 to 86 of 118 are 98.46 pct identical to residues 1 to 65 of 290 from GenPept.129 : >gb|AAL99256.1| (AY082443) unknown [Escherichia coli]; hypothetical protein complement(269022..269378) Escherichia coli CFT073 1036483 NP_752234.1 CDS c0290 NC_004431.1 269537 270640 R Residues 32 to 289 of 367 are 93.82 pct identical to residues 5 to 263 of 268 from GenPept.129 : >gb|AAL67361.1|AF447814_29 (AF447814) unknown [Escherichia coli]; hypothetical protein complement(269537..270640) Escherichia coli CFT073 1036470 NP_752235.1 CDS c0291 NC_004431.1 271030 271638 D Residues 3 to 202 of 202 are 100.00 pct identical to residues 1 to 200 of 200 from GenPept.129 : >gb|AAL67363.1|AF447814_31 (AF447814) recombinase [Escherichia coli]; hypothetical protein 271030..271638 Escherichia coli CFT073 1036481 YP_004853796.1 CDS c0292 NC_004431.1 271866 272603 D hypothetical protein 271866..272603 Escherichia coli CFT073 1036468 NP_752237.1 CDS c0293 NC_004431.1 272721 273530 R Residues 1 to 269 of 269 are 100.00 pct identical to residues 1 to 269 of 269 from GenPept.129 : >gb|AAL67365.1|AF447814_33 (AF447814) unknown [Escherichia coli]; hypothetical protein complement(272721..273530) Escherichia coli CFT073 1037725 NP_752238.1 CDS c0294 NC_004431.1 274013 276178 D Residues 1 to 530 of 721 are 100.00 pct identical to residues 1 to 530 of 536 from GenPept.129 : >gb|AAL67366.1|AF447814_34 (AF447814) truncated ferric siderophore receptor [Escherichia coli]; hypothetical protein 274013..276178 Escherichia coli CFT073 1040052 NP_752239.1 CDS c0295 NC_004431.1 276186 277178 D Residues 1 to 330 of 330 are 99.39 pct identical to residues 1 to 332 of 332 from GenPept.129 : >gb|AAL67368.1|AF447814_36 (AF447814) iron-chelating periplasmic-binding protein [Escherichia coli]; hypothetical protein 276186..277178 Escherichia coli CFT073 1036464 NP_752240.1 CDS c0296 NC_004431.1 277197 278255 D Residues 1 to 352 of 352 are 100.00 pct identical to residues 1 to 352 of 352 from GenPept.129 : >gb|AAL67369.1|AF447814_37 (AF447814) permease [Escherichia coli]; hypothetical protein 277197..278255 Escherichia coli CFT073 1036457 NP_752241.1 CDS c0297 NC_004431.1 278252 279019 D Residues 1 to 255 of 255 are 100.00 pct identical to residues 1 to 255 of 255 from GenPept.129 : >gb|AAL67370.1|AF447814_38 (AF447814) ferric-enterobactin-transport protein [Escherichia coli]; hypothetical protein 278252..279019 Escherichia coli CFT073 1036460 NP_752242.1 CDS c0298 NC_004431.1 279868 280236 D hypothetical protein 279868..280236 Escherichia coli CFT073 1036583 NP_752243.1 CDS c0299 NC_004431.1 279881 280306 D hypothetical protein 279881..280306 Escherichia coli CFT073 1036456 NP_752244.1 CDS c0300 NC_004431.1 279920 280066 R hypothetical protein complement(279920..280066) Escherichia coli CFT073 1036442 NP_752245.1 CDS c0301 NC_004431.1 280838 281023 D hypothetical protein 280838..281023 Escherichia coli CFT073 1036452 NP_752246.1 CDS c0302 NC_004431.1 281124 281261 D hypothetical protein 281124..281261 Escherichia coli CFT073 1036458 NP_752247.1 CDS c0303 NC_004431.1 281170 281313 R hypothetical protein complement(281170..281313) Escherichia coli CFT073 1036436 NP_752248.1 CDS c0304 NC_004431.1 281760 281960 D hypothetical protein 281760..281960 Escherichia coli CFT073 1036453 NP_752249.1 CDS c0305 NC_004431.1 281863 282471 R Residues 1 to 202 of 202 are 92.07 pct identical to residues 1 to 202 of 202 from GenPept.129 : >gb|AAL08467.1| (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein complement(281863..282471) Escherichia coli CFT073 1036445 NP_752250.1 CDS c0306 NC_004431.1 282559 282765 R Escherichia coli O157:H7 ortholog: z1627; hypothetical protein complement(282559..282765) Escherichia coli CFT073 1036446 NP_752251.1 CDS c0307 NC_004431.1 283149 283940 R Residues 9 to 164 of 263 are 96.15 pct identical to residues 1 to 156 of 156 from GenPept.129 : >gb|AAK00470.1| (AF200692) unknown [Shigella flexneri 2a]; hypothetical protein complement(283149..283940) Escherichia coli CFT073 1036440 NP_752252.1 CDS c0308 NC_004431.1 285015 285155 D Escherichia coli K-12 ortholog: b0460; Escherichia coli O157:H7 ortholog: z0573; hemolysin expression modulating protein 285015..285155 Escherichia coli CFT073 1035985 NP_752253.1 CDS c0309 NC_004431.1 285387 285986 D Escherichia coli O157:H7 ortholog: z1567; hypothetical protein 285387..285986 Escherichia coli CFT073 1036435 NP_752254.1 CDS c0310 NC_004431.1 286352 286741 D Residues 3 to 129 of 129 are 88.97 pct identical to residues 1 to 127 of 127 from GenPept.129 : >gb|AAK00467.1| (AF200692) unknown [Shigella flexneri 2a]; hypothetical protein 286352..286741 Escherichia coli CFT073 1036443 NP_752255.1 CDS c0311 NC_004431.1 286738 287163 D Residues 15 to 119 of 141 are 36.36 pct identical to residues 44 to 153 of 173 from GenPept.129 : >gb|AAL08463.1|AF326777_38 (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 286738..287163 Escherichia coli CFT073 1036439 NP_752256.1 CDS c0312 NC_004431.1 287365 287607 D Residues 30 to 80 of 80 are 76.47 pct identical to residues 48 to 98 of 98 from GenPept.129 : >gb|AAL08431.1|AF326777_6 (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 287365..287607 Escherichia coli CFT073 1036424 NP_752257.1 CDS c0313 NC_004431.1 287635 288201 D hypothetical protein 287635..288201 Escherichia coli CFT073 1036433 NP_752258.1 CDS c0314 NC_004431.1 288254 288409 D hypothetical protein 288254..288409 Escherichia coli CFT073 1036428 NP_752259.1 CDS c0315 NC_004431.1 288306 288521 D Residues 8 to 71 of 71 are 93.75 pct identical to residues 1 to 64 of 64 from GenPept.129 : >dbj|BAB34790.1| (AP002554) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 288306..288521 Escherichia coli CFT073 1036420 NP_752260.1 CDS c0316 NC_004431.1 288427 288717 R Residues 1 to 68 of 96 are 70.58 pct identical to residues 69 to 136 of 148 from GenPept.129 : >gb|AAL67420.1|AF447814_88 (AF447814) unknown [Escherichia coli]; hypothetical protein complement(288427..288717) Escherichia coli CFT073 1036427 NP_752261.1 CDS c0317 NC_004431.1 288649 288786 D Escherichia coli O157:H7 ortholog: z1627; hypothetical protein 288649..288786 Escherichia coli CFT073 1036422 NP_752262.1 CDS c0318 NC_004431.1 289106 289744 R Residues 1 to 210 of 212 are 65.87 pct identical to residues 1 to 211 of 212 from GenPept.129 : >gb|AAL20848.1| (AE008786) ribose 5-phosphate isomerase [Salmonella typhimurium LT2]; hypothetical protein complement(289106..289744) Escherichia coli CFT073 1036430 NP_752263.1 CDS c0319 NC_004431.1 289986 291158 D Residues 1 to 386 of 390 are 65.02 pct identical to residues 1 to 386 of 388 from SwissProt.40 : >sp|Q59418|OGL_ERWCA OLIGOGALACTURONIDE LYASE; oligogalacturonide lyase 289986..291158 Escherichia coli CFT073 1036419 NP_752264.1 CDS c0320 NC_004431.1 290959 291114 R hypothetical protein complement(290959..291114) Escherichia coli CFT073 1036426 NP_752265.1 CDS c0321 NC_004431.1 291188 291988 D Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase 291188..291988 Escherichia coli CFT073 1040242 NP_752266.1 CDS c0322 NC_004431.1 292732 294246 D Residues 16 to 496 of 504 are 56.93 pct identical to residues 13 to 495 of 508 from GenPept.129 : >emb|CAC44457.1| (AJ305143) oligogalacturonide transporter [Pectobacterium chrysanthemi]; oligogalacturonide transporter 292732..294246 Escherichia coli CFT073 1036423 NP_752267.1 CDS c0323 NC_004431.1 294176 296482 D Residues 21 to 729 of 768 are 40.62 pct identical to residues 8 to 686 of 732 from GenPept.129 : >gb|AAL51034.1|AF454849_1 (AF454849) pectate lyase [Klebsiella oxytoca]; exopolygalacturonate lyase 294176..296482 Escherichia coli CFT073 1036416 NP_752268.1 CDS c0324 NC_004431.1 295181 295303 R hypothetical protein complement(295181..295303) Escherichia coli CFT073 1036417 NP_752269.1 CDS c0325 NC_004431.1 296575 297555 D hypothetical protein 296575..297555 Escherichia coli CFT073 1034963 NP_752270.1 CDS c0326 NC_004431.1 297875 298303 R Residues 1 to 142 of 142 are 86.71 pct identical to residues 83 to 225 of 228 from GenPept.129 : >emb|CAC43418.1| (X16664) hypothetical protein [Escherichia coli]; hypothetical protein complement(297875..298303) Escherichia coli CFT073 1036418 NP_752271.1 CDS c0327 NC_004431.1 298646 299116 R Escherichia coli O157:H7 ortholog: z1633; hypothetical protein complement(298646..299116) Escherichia coli CFT073 1036403 NP_752272.1 CDS c0328 NC_004431.1 299622 299861 R hypothetical protein complement(299622..299861) Escherichia coli CFT073 1036408 NP_752273.1 CDS c0329 NC_004431.1 299991 300116 D hypothetical protein 299991..300116 Escherichia coli CFT073 1036406 NP_752274.1 CDS c0330 NC_004431.1 300643 301428 R Residues 2 to 261 of 261 are 83.58 pct identical to residues 1 to 261 of 261 from GenPept.129 : >gb|AAL22652.1| (AE008876) regulatory protein, deoR family [Salmonella typhimurium LT2]; deoxyribose operon repressor complement(300643..301428) Escherichia coli CFT073 1036413 NP_752275.1 CDS c0331 NC_004431.1 301731 302651 D Residues 1 to 306 of 306 are 96.07 pct identical to residues 1 to 306 of 306 from GenPept.129 : >emb|CAC34669.1| (AX087925) unnamed protein product [Salmonella typhi]; ribokinase 301731..302651 Escherichia coli CFT073 1036407 NP_752276.1 CDS c0332 NC_004431.1 302679 303995 D Residues 1 to 438 of 438 are 96.11 pct identical to residues 1 to 438 of 438 from GenPept.129 : >gb|AAL22650.1| (AE008876) L-fucose permease [Salmonella typhimurium LT2]; L-fucose permease 302679..303995 Escherichia coli CFT073 1036394 NP_752277.1 CDS c0333 NC_004431.1 304007 305020 D Residues 1 to 336 of 337 are 83.03 pct identical to residues 1 to 336 of 337 from GenPept.129 : >gb|AAL22649.1| (AE008876) cytoplasmic protein [Salmonella typhimurium LT2]; cytoplasmic protein 304007..305020 Escherichia coli CFT073 1036399 NP_752278.1 CDS ulaA NC_004431.1 305943 307199 R membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC complement(305943..307199) Escherichia coli CFT073 1036393 NP_752279.1 CDS c0335 NC_004431.1 307212 307499 R Residues 1 to 95 of 95 are 96.84 pct identical to residues 1 to 95 of 95 from GenPept.129 : >gb|AAK27336.1| (AF286670) unknown [Escherichia coli]; hypothetical protein complement(307212..307499) Escherichia coli CFT073 1036389 NP_752280.1 CDS c0336 NC_004431.1 307515 307958 R EIIA-(C)MTL; Escherichia coli K-12 ortholog: b2934; Escherichia coli O157:H7 ortholog: z4278; PTS system, mannitol (Cryptic)-specific IIA component complement(307515..307958) Escherichia coli CFT073 1036383 NP_752281.1 CDS c0337 NC_004431.1 308229 309260 D Residues 12 to 307 of 343 are 33.11 pct identical to residues 5 to 298 of 313 from MG1655 : b3438; hypothetical protein 308229..309260 Escherichia coli CFT073 1036376 NP_752282.1 CDS c0338 NC_004431.1 309547 309678 R hypothetical protein complement(309547..309678) Escherichia coli CFT073 1036388 NP_752283.1 CDS c0339 NC_004431.1 309763 309915 R hypothetical protein complement(309763..309915) Escherichia coli CFT073 1036382 NP_752284.1 CDS c0340 NC_004431.1 309979 310638 D Escherichia coli O157:H7 ortholog: z1635; hypothetical protein 309979..310638 Escherichia coli CFT073 1036385 NP_752285.1 CDS c0341 NC_004431.1 310629 310817 R hypothetical protein complement(310629..310817) Escherichia coli CFT073 1036373 NP_752286.1 CDS c0345 NC_004431.1 312645 322295 D Residues 9 to 3039 of 3216 are 32.79 pct identical to residues 52 to 3078 of 3295 from GenPept.129 : >emb|CAC89456.1| (AJ414143) adhesin [Yersinia pestis]; ShlA/HecA/FhaA exofamily protein 312645..322295 Escherichia coli CFT073 1036378 NP_752287.1 CDS c0348 NC_004431.1 323695 323937 D hypothetical protein 323695..323937 Escherichia coli CFT073 1040030 NP_752288.1 CDS c0349 NC_004431.1 324082 325206 D Escherichia coli O157:H7 ortholog: z2082; transposase 324082..325206 Escherichia coli CFT073 1036461 NP_752289.1 CDS c0350 NC_004431.1 326209 330324 R Residues 1 to 1371 of 1371 are 96.28 pct identical to residues 1 to 1372 of 1372 from GenPept.129 : >gb|AAD23953.1|AF097644_1 (AF097644) Pic serine protease precursor [Escherichia coli]; Pic serine protease complement(326209..330324) Escherichia coli CFT073 1036227 NP_752290.1 CDS c0351 NC_004431.1 330391 330552 D hypothetical protein 330391..330552 Escherichia coli CFT073 1036363 NP_752291.1 CDS c0352 NC_004431.1 331417 331623 R Escherichia coli O157:H7 ortholog: z1647; partial transposase complement(331417..331623) Escherichia coli CFT073 1036358 NP_752292.1 CDS c0354 NC_004431.1 332304 332630 R Escherichia coli O157:H7 ortholog: z2982; hypothetical protein complement(332304..332630) Escherichia coli CFT073 1036360 NP_752293.1 CDS c0355 NC_004431.1 333750 334046 D Residues 2 to 98 of 98 are 83.50 pct identical to residues 166 to 262 of 539 from GenPept.129 : >gb|AAL57569.1|AF453441_53 (AF453441) transposase [Escherichia coli]; hypothetical protein 333750..334046 Escherichia coli CFT073 1036361 NP_752294.1 CDS c0357 NC_004431.1 334492 334875 D Residues 1 to 127 of 127 are 89.31 pct identical to residues 409 to 539 of 539 from GenPept.129 : >gb|AAL57569.1|AF453441_53 (AF453441) transposase [Escherichia coli]; hypothetical protein 334492..334875 Escherichia coli CFT073 1036356 NP_752295.1 CDS c0358 NC_004431.1 334872 335351 D hypothetical protein 334872..335351 Escherichia coli CFT073 1036349 NP_752296.1 CDS c0359 NC_004431.1 335169 335291 R Residues 1 to 38 of 40 are 65.78 pct identical to residues 1 to 38 of 173 from GenPept.129 : >gb|AAK29065.1|AF345899_1 (AF345899) OrfA [Klebsiella pneumoniae]; hypothetical protein complement(335169..335291) Escherichia coli CFT073 1036355 NP_752297.1 CDS c0360 NC_004431.1 336046 337293 D Residues 93 to 374 of 415 are 22.55 pct identical to residues 108 to 400 of 445 from GenPept.129 : >gb|AAF94774.1| (AE004240) agglutination protein [Vibrio cholerae]; hypothetical protein 336046..337293 Escherichia coli CFT073 1036346 NP_752298.1 CDS c0361 NC_004431.1 337318 339465 D Escherichia coli O157:H7 ortholog: z0634; cytoplasmic membrane export protein 337318..339465 Escherichia coli CFT073 1036345 NP_752299.1 CDS c0362 NC_004431.1 339511 340773 D Escherichia coli O157:H7 ortholog: z0635; membrane spanning export protein 339511..340773 Escherichia coli CFT073 1036351 NP_752300.1 CDS c0363 NC_004431.1 340972 345804 D Residues 83 to 1160 of 1610 are 23.56 pct identical to residues 3030 to 4053 of 4106 from GenPept.129 : >emb|CAD18331.1| (AL646083) HEMAGGLUTININ/HEMOLYSIN-RELATED PROTEIN [Ralstonia solanacearum]; RTX family exoprotein A gene 340972..345804 Escherichia coli CFT073 1036339 NP_752301.1 CDS c0364 NC_004431.1 345925 346407 D Residues 1 to 156 of 160 are 33.12 pct identical to residues 1 to 157 of 157 from GenPept.129 : >gb|AAL31494.1|AF399847_3 (AF399847) ORF-156F [Escherichia coli]; hypothetical protein 345925..346407 Escherichia coli CFT073 1036344 NP_752302.1 CDS c0365 NC_004431.1 346408 346938 D hypothetical protein 346408..346938 Escherichia coli CFT073 1039792 NP_752303.1 CDS c0366 NC_004431.1 346889 347158 R hypothetical protein complement(346889..347158) Escherichia coli CFT073 1036350 NP_752304.1 CDS c0367 NC_004431.1 347299 347775 R Residues 14 to 152 of 158 are 29.11 pct identical to residues 6 to 160 of 160 from GenPept.129 : >emb|CAA79750.1| (Z21626) transposase [Geobacillus stearothermophilus]; hypothetical protein complement(347299..347775) Escherichia coli CFT073 1036336 NP_752305.1 CDS c0368 NC_004431.1 348228 348353 D hypothetical protein 348228..348353 Escherichia coli CFT073 1036337 NP_752306.1 CDS yafV NC_004431.1 348625 349404 R Escherichia coli K-12 ortholog: b0219; Escherichia coli O157:H7 ortholog: z0276; hypothetical protein complement(348625..349404) Escherichia coli CFT073 1035094 NP_752307.1 CDS ykfE NC_004431.1 349549 350022 D inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 349549..350022 Escherichia coli CFT073 1036338 NP_752308.2 CDS fadE NC_004431.1 350065 352509 R functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase complement(350065..352509) Escherichia coli CFT073 1040416 NP_752309.2 CDS gmhA NC_004431.1 352749 353327 D catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 352749..353327 Escherichia coli CFT073 1036332 NP_752310.1 CDS yafJ NC_004431.1 353517 354299 D Escherichia coli K-12 ortholog: b0223; Escherichia coli O157:H7 ortholog: z0281; hypothetical protein 353517..354299 Escherichia coli CFT073 1035969 NP_752311.1 CDS yafK NC_004431.1 354270 355010 R Escherichia coli K-12 ortholog: b0224; Escherichia coli O157:H7 ortholog: z0282; hypothetical protein complement(354270..355010) Escherichia coli CFT073 1036334 NP_752312.1 CDS c0375 NC_004431.1 355267 355404 R hypothetical protein complement(355267..355404) Escherichia coli CFT073 1036327 NP_752313.1 CDS yafL NC_004431.1 355379 356071 D Escherichia coli K-12 ortholog: b0227; Escherichia coli O157:H7 ortholog: z0287; lipoprotein yafL 355379..356071 Escherichia coli CFT073 1036330 NP_752314.1 CDS fhiA NC_004431.1 356346 358085 R Escherichia coli K-12 ortholog: b0229; Escherichia coli O157:H7 ortholog: z0290; FhiA protein complement(356346..358085) Escherichia coli CFT073 1036328 NP_752315.1 CDS mbhA NC_004431.1 358027 358815 D Escherichia coli K-12 ortholog: b0230; Escherichia coli O157:H7 ortholog: z0291; hypothetical protein 358027..358815 Escherichia coli CFT073 1039617 NP_752316.1 CDS dinP NC_004431.1 358886 359941 D involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 358886..359941 Escherichia coli CFT073 1036320 NP_752317.1 CDS yafP NC_004431.1 359938 360390 D Escherichia coli K-12 ortholog: b0234; Escherichia coli O157:H7 ortholog: z0295; hypothetical protein 359938..360390 Escherichia coli CFT073 1036325 NP_752318.2 CDS c0381 NC_004431.1 360580 361719 D mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY; hypothetical protein 360580..361719 Escherichia coli CFT073 1036322 NP_752319.2 CDS prfH NC_004431.1 361830 362330 D similar to release factor 1 and 2; peptide chain release factor-like protein 361830..362330 Escherichia coli CFT073 1036323 NP_752320.1 CDS pepD NC_004431.1 362387 363844 R Escherichia coli K-12 ortholog: b0237; Escherichia coli O157:H7 ortholog: z0298; aminoacyl-histidine dipeptidase complement(362387..363844) Escherichia coli CFT073 1036317 NP_752321.1 CDS gpt NC_004431.1 364105 364563 D catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 364105..364563 Escherichia coli CFT073 1036319 NP_752322.1 CDS c0385 NC_004431.1 364237 364689 R hypothetical protein complement(364237..364689) Escherichia coli CFT073 1036311 NP_752323.1 CDS frsA NC_004431.1 364655 365899 D forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 364655..365899 Escherichia coli CFT073 1036321 NP_752324.1 CDS crl NC_004431.1 365957 366358 D involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 365957..366358 Escherichia coli CFT073 1036309 NP_752325.1 CDS phoE NC_004431.1 366397 367458 R Escherichia coli K-12 ortholog: b0241; Escherichia coli O157:H7 ortholog: z0302; outer membrane phosphoporin protein E complement(366397..367458) Escherichia coli CFT073 1036315 NP_752326.2 CDS proB NC_004431.1 367741 368844 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 367741..368844 Escherichia coli CFT073 1036313 NP_752327.1 CDS proA NC_004431.1 368856 370109 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 368856..370109 Escherichia coli CFT073 1036306 NP_752328.1 CDS c0391 NC_004431.1 370454 370792 D Residues 1 to 111 of 112 are 63.06 pct identical to residues 1 to 111 of 404 from GenPept.129 : >emb|CAC89731.1| (AJ414145) integrase [Yersinia pestis]; CP4-like integrase 370454..370792 Escherichia coli CFT073 1036310 NP_752329.1 CDS c0392 NC_004431.1 371227 371751 R Residues 11 to 172 of 174 are 46.91 pct identical to residues 1 to 162 of 166 from SwissProt.40 : >sp|P42192|PRSX_ECOLI PRSX PROTEIN; hypothetical protein complement(371227..371751) Escherichia coli CFT073 1036305 NP_752330.1 CDS c0393 NC_004431.1 371877 376007 R Residues 1 to 1376 of 1376 are 79.04 pct identical to residues 1 to 1377 of 1377 from GenPept.129 : >emb|CAA11507.1| (AJ223631) haemoglobin protease [Escherichia coli]; hemoglobin protease complement(371877..376007) Escherichia coli CFT073 1034958 NP_752331.1 CDS c0394 NC_004431.1 376320 376517 D hypothetical protein 376320..376517 Escherichia coli CFT073 1039704 NP_752332.1 CDS c0395 NC_004431.1 376435 376560 D hypothetical protein 376435..376560 Escherichia coli CFT073 1036307 NP_752333.1 CDS c0396 NC_004431.1 376600 376815 D IS1a/IS1b/IS1c/IS1d; Escherichia coli K-12 ortholog: b3444; insertion element IS1 1/2/3/5/6 protein insA 376600..376815 Escherichia coli CFT073 1036303 NP_752334.1 CDS c0397 NC_004431.1 377117 377293 D Residues 1 to 58 of 58 are 87.93 pct identical to residues 74 to 131 of 131 from GenPept.129 : >gb|AAF28142.1|AF153317_40 (AF153317) InsB [Shigella dysenteriae]; InsB protein 377117..377293 Escherichia coli CFT073 1036302 NP_752335.1 CDS c0398 NC_004431.1 377672 377854 D hypothetical protein 377672..377854 Escherichia coli CFT073 1036304 NP_752336.1 CDS yagU NC_004431.1 378117 378731 D Escherichia coli K-12 ortholog: b0287; Escherichia coli O157:H7 ortholog: z0353; hypothetical protein 378117..378731 Escherichia coli CFT073 1036298 NP_752337.1 CDS yagV NC_004431.1 379616 380371 R Escherichia coli K-12 ortholog: b0289; Escherichia coli O157:H7 ortholog: z0356; hypothetical protein complement(379616..380371) Escherichia coli CFT073 1036301 NP_752338.1 CDS yagW NC_004431.1 380295 381938 R Escherichia coli K-12 ortholog: b0290; Escherichia coli O157:H7 ortholog: z0357; hypothetical protein complement(380295..381938) Escherichia coli CFT073 1036297 NP_752339.1 CDS yagX NC_004431.1 381928 384453 R Escherichia coli K-12 ortholog: b0291; Escherichia coli O157:H7 ortholog: z0358; hypothetical protein complement(381928..384453) Escherichia coli CFT073 1036299 NP_752340.1 CDS yagY NC_004431.1 384479 385195 R Escherichia coli K-12 ortholog: b0292; Escherichia coli O157:H7 ortholog: z0359; hypothetical protein complement(384479..385195) Escherichia coli CFT073 1040494 NP_752341.1 CDS matB NC_004431.1 385204 385791 R Escherichia coli K-12 ortholog: b0293; Escherichia coli O157:H7 ortholog: z0360; hypothetical protein complement(385204..385791) Escherichia coli CFT073 1036296 NP_752342.1 CDS matA NC_004431.1 385866 386456 R Escherichia coli K-12 ortholog: b0294; Escherichia coli O157:H7 ortholog: z0361; hypothetical protein complement(385866..386456) Escherichia coli CFT073 1036295 NP_752343.1 CDS rpmJ NC_004431.1 387492 387635 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 complement(387492..387635) Escherichia coli CFT073 1036291 NP_752344.2 CDS rpmE2 NC_004431.1 387632 387895 R RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(387632..387895) Escherichia coli CFT073 1040414 NP_752345.1 CDS c0408 NC_004431.1 388835 388978 R Residues 1 to 47 of 47 are 91.48 pct identical to residues 334 to 380 of 380 from GenPept.129 : >gb|AAG54626.1|AE005207_1 (AE005207) oxidoreductase [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(388835..388978) Escherichia coli CFT073 1036294 NP_752346.1 CDS c0409 NC_004431.1 388990 389979 R Escherichia coli O157:H7 ortholog: z0369; oxidoreductase complement(388990..389979) Escherichia coli CFT073 1036293 NP_752347.1 CDS c0410 NC_004431.1 390151 391071 R Escherichia coli K-12 ortholog: b1327; Escherichia coli O157:H7 ortholog: z0370; hypothetical protein complement(390151..391071) Escherichia coli CFT073 1036292 NP_752348.1 CDS c0411 NC_004431.1 391165 392154 D Escherichia coli O157:H7 ortholog: z0371; LysR family transcriptional regulator 391165..392154 Escherichia coli CFT073 1036796 NP_752349.1 CDS c0412 NC_004431.1 392279 393247 D Escherichia coli K-12 ortholog: b1328; Escherichia coli O157:H7 ortholog: z2439; transcriptional regulator YcjZ 392279..393247 Escherichia coli CFT073 1036288 NP_752350.1 CDS c0413 NC_004431.1 393278 394267 R Residues 6 to 290 of 329 are 50.51 pct identical to residues 13 to 301 of 307 from SwissProt.40 : >sp|P40691|A115_TOBAC AUXIN-INDUCED PROTEIN PCNT115; aldo/keto reductase complement(393278..394267) Escherichia coli CFT073 1035013 NP_752351.1 CDS c0414 NC_004431.1 394294 395145 R Escherichia coli K-12 ortholog: b3012; Escherichia coli O157:H7 ortholog: z0374; 2,5-diketo-D-gluconate reductase A complement(394294..395145) Escherichia coli CFT073 1036290 NP_752352.1 CDS eaeH NC_004431.1 395711 399961 D Escherichia coli O157:H7 ortholog: z0375; adhesin 395711..399961 Escherichia coli CFT073 1036283 NP_752353.1 CDS ykgA NC_004431.1 400086 400976 R Escherichia coli K-12 ortholog: b0300; Escherichia coli O157:H7 ortholog: z0376; transcriptional regulator YkgA complement(400086..400976) Escherichia coli CFT073 1036289 NP_752354.1 CDS c0417 NC_004431.1 401176 402060 D Escherichia coli K-12 ortholog: b3012; Escherichia coli O157:H7 ortholog: z0377; 2,5-diketo-D-gluconate reductase A 401176..402060 Escherichia coli CFT073 1036281 NP_752355.1 CDS ykgB NC_004431.1 402220 402822 R Escherichia coli K-12 ortholog: b0301; Escherichia coli O157:H7 ortholog: z0378; hypothetical protein complement(402220..402822) Escherichia coli CFT073 1040057 NP_752356.1 CDS ykgI NC_004431.1 402825 403076 R Escherichia coli K-12 ortholog: b0303; Escherichia coli O157:H7 ortholog: z0380; hypothetical protein complement(402825..403076) Escherichia coli CFT073 1036275 NP_752357.2 CDS ykgC NC_004431.1 403170 404495 R Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase complement(403170..404495) Escherichia coli CFT073 1035927 NP_752358.1 CDS ykgD NC_004431.1 404671 405576 D Escherichia coli K-12 ortholog: b0305; Escherichia coli O157:H7 ortholog: z0382; transcriptional regulator YkgD 404671..405576 Escherichia coli CFT073 1036282 NP_752359.1 CDS ykgE NC_004431.1 406102 406821 D Escherichia coli K-12 ortholog: b0306; Escherichia coli O157:H7 ortholog: z0384; hypothetical protein 406102..406821 Escherichia coli CFT073 1036277 NP_752360.1 CDS ykgF NC_004431.1 406832 408259 D Escherichia coli K-12 ortholog: b0307; Escherichia coli O157:H7 ortholog: z0385; electron transport protein ykgF 406832..408259 Escherichia coli CFT073 1036266 NP_752361.3 CDS ykgG NC_004431.1 408099 408947 D Escherichia coli K-12 ortholog: b0308; Escherichia coli O157:H7 ortholog: z0386; hypothetical protein 408099..408947 Escherichia coli CFT073 1036269 NP_752362.1 CDS ykgH NC_004431.1 409190 409858 R Escherichia coli K-12 ortholog: b0310; Escherichia coli O157:H7 ortholog: z0388; hypothetical protein complement(409190..409858) Escherichia coli CFT073 1036270 NP_752363.1 CDS c0426 NC_004431.1 410042 412372 R Residues 7 to 372 of 776 are 88.31 pct identical to residues 1 to 366 of 369 from GenPept.129 : >gb|AAG54646.1|AE005209_2 (AE005209) Z0390 gene product [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(410042..412372) Escherichia coli CFT073 1036267 NP_752364.1 CDS c0427 NC_004431.1 412381 413142 R Escherichia coli O157:H7 ortholog: z0391; hypothetical protein complement(412381..413142) Escherichia coli CFT073 1036264 NP_752365.1 CDS c0428 NC_004431.1 413296 414000 R Escherichia coli O157:H7 ortholog: z0392; hypothetical protein complement(413296..414000) Escherichia coli CFT073 1038753 NP_752366.1 CDS c0429 NC_004431.1 413972 414127 R Escherichia coli O157:H7 ortholog: z0393; hypothetical protein complement(413972..414127) Escherichia coli CFT073 1036259 NP_752367.1 CDS c0430 NC_004431.1 414420 415022 R Escherichia coli K-12 ortholog: b4312; Type 1 fimbriae regulatory protein fimB complement(414420..415022) Escherichia coli CFT073 1036265 NP_752368.2 CDS betA NC_004431.1 416069 417739 R catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase complement(416069..417739) Escherichia coli CFT073 1036260 NP_752369.1 CDS betB NC_004431.1 417753 419228 R catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase complement(417753..419228) Escherichia coli CFT073 1036263 NP_752370.1 CDS betI NC_004431.1 419239 419844 R HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI complement(419239..419844) Escherichia coli CFT073 1036258 NP_752371.1 CDS betT NC_004431.1 419955 421988 D proton-motive-force-driven choline transporter; choline transport protein BetT 419955..421988 Escherichia coli CFT073 1036262 NP_752372.1 CDS c0435 NC_004431.1 422858 423952 D Escherichia coli K-12 ortholog: b0315; Escherichia coli O157:H7 ortholog: z0403; hypothetical protein 422858..423952 Escherichia coli CFT073 1036256 NP_752373.1 CDS yahB NC_004431.1 423994 424926 R Escherichia coli K-12 ortholog: b0316; Escherichia coli O157:H7 ortholog: z0405; transcriptional regulator YahB complement(423994..424926) Escherichia coli CFT073 1036257 NP_752374.1 CDS yahC NC_004431.1 425018 425515 R Escherichia coli K-12 ortholog: b0317; Escherichia coli O157:H7 ortholog: z0406; hypothetical protein complement(425018..425515) Escherichia coli CFT073 1034971 NP_752375.1 CDS c0438 NC_004431.1 425592 425834 D hypothetical protein 425592..425834 Escherichia coli CFT073 1036727 NP_752376.1 CDS yahD NC_004431.1 425773 426378 D Escherichia coli K-12 ortholog: b0318; Escherichia coli O157:H7 ortholog: z0407; ankyrin repeat-containing protein 425773..426378 Escherichia coli CFT073 1036250 NP_752377.1 CDS yahE NC_004431.1 426418 427281 D Escherichia coli K-12 ortholog: b0319; Escherichia coli O157:H7 ortholog: z0408; hypothetical protein 426418..427281 Escherichia coli CFT073 1036253 NP_752378.1 CDS c0441 NC_004431.1 427271 428818 D Escherichia coli K-12 ortholog: b0320; Escherichia coli O157:H7 ortholog: z0409; hypothetical protein 427271..428818 Escherichia coli CFT073 1036255 NP_752379.1 CDS c0444 NC_004431.1 430662 431612 D forms a homodimer; may be used to synthesize carbomyl phosphate from ATP and carbamate; carbamate kinase 430662..431612 Escherichia coli CFT073 1036252 NP_752380.1 CDS yahJ NC_004431.1 431622 433004 D metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain; deaminase 431622..433004 Escherichia coli CFT073 1036244 NP_752381.1 CDS c0446 NC_004431.1 433226 433381 R hypothetical protein complement(433226..433381) Escherichia coli CFT073 1036247 NP_752382.1 CDS yahK NC_004431.1 433381 434430 D Escherichia coli K-12 ortholog: b0325; Escherichia coli O157:H7 ortholog: z0420; hypothetical protein 433381..434430 Escherichia coli CFT073 1036286 NP_752383.1 CDS yahN NC_004431.1 435312 435986 R Escherichia coli K-12 ortholog: b0328; Escherichia coli O157:H7 ortholog: z0424; hypothetical protein complement(435312..435986) Escherichia coli CFT073 1036230 NP_752384.1 CDS yahO NC_004431.1 436133 436408 D Escherichia coli K-12 ortholog: b0329; Escherichia coli O157:H7 ortholog: z0425; hypothetical protein 436133..436408 Escherichia coli CFT073 1036242 NP_752385.1 CDS prpR NC_004431.1 436509 438095 R Escherichia coli K-12 ortholog: b0330; Escherichia coli O157:H7 ortholog: z0426; propionate catabolism operon regulatory protein complement(436509..438095) Escherichia coli CFT073 1036232 NP_752386.1 CDS prpB NC_004431.1 438334 439224 D catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 438334..439224 Escherichia coli CFT073 1039779 NP_752387.1 CDS prpC NC_004431.1 439384 440553 D catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 439384..440553 Escherichia coli CFT073 1036234 NP_752388.1 CDS prpD NC_004431.1 440587 442038 D functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase 440587..442038 Escherichia coli CFT073 1037564 NP_752389.1 CDS prpE NC_004431.1 442078 443964 D catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase 442078..443964 Escherichia coli CFT073 1038450 NP_752390.1 CDS codB NC_004431.1 444289 445548 D Escherichia coli K-12 ortholog: b0336; Escherichia coli O157:H7 ortholog: z0432; cytosine permease 444289..445548 Escherichia coli CFT073 1036222 NP_752391.1 CDS codA NC_004431.1 445523 446821 D Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase 445523..446821 Escherichia coli CFT073 1040512 NP_752392.1 CDS lacA NC_004431.1 446942 447604 R transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown; galactoside O-acetyltransferase complement(446942..447604) Escherichia coli CFT073 1036231 NP_752393.1 CDS lacY NC_004431.1 447619 448872 R lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease complement(447619..448872) Escherichia coli CFT073 1036217 NP_752394.1 CDS lacZ NC_004431.1 448924 451998 R forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase complement(448924..451998) Escherichia coli CFT073 1036228 NP_752395.1 CDS c0460 NC_004431.1 452122 452388 R Residues 12 to 88 of 88 are 88.31 pct identical to residues 284 to 360 of 360 from GenPept.129 : >gb|AAL59004.1| (AY070365) Lac repressor [Expression vector pFHC2102]; LacI protein complement(452122..452388) Escherichia coli CFT073 1040087 NP_752396.3 CDS yaiL NC_004431.1 453388 453945 D Escherichia coli K-12 ortholog: b0354; Escherichia coli O157:H7 ortholog: z0454; hypothetical protein 453388..453945 Escherichia coli CFT073 1036225 NP_752397.1 CDS c0463 NC_004431.1 453448 453999 R hypothetical protein complement(453448..453999) Escherichia coli CFT073 1036215 NP_752398.1 CDS yaiM NC_004431.1 454173 455006 R Escherichia coli K-12 ortholog: b0355; Escherichia coli O157:H7 ortholog: z0455; hypothetical protein complement(454173..455006) Escherichia coli CFT073 1040106 NP_752399.1 CDS adhC NC_004431.1 455099 456208 R Escherichia coli K-12 ortholog: b0356; Escherichia coli O157:H7 ortholog: z0456; alcohol dehydrogenase complement(455099..456208) Escherichia coli CFT073 1036214 NP_752400.1 CDS yaiN NC_004431.1 456243 456539 R formaldehyde-induced negative regulator of the frmRAB operon; regulator protein FrmR complement(456243..456539) Escherichia coli CFT073 1036220 NP_752401.1 CDS c0467 NC_004431.1 456705 457478 R Escherichia coli K-12 ortholog: b0358; hypothetical protein complement(456705..457478) Escherichia coli CFT073 1035951 NP_752402.1 CDS c0468 NC_004431.1 457480 458004 R Escherichia coli K-12 ortholog: b0359; transferase complement(457480..458004) Escherichia coli CFT073 1036211 NP_752403.1 CDS c0469 NC_004431.1 458039 459235 R Escherichia coli K-12 ortholog: b0363; hypothetical protein complement(458039..459235) Escherichia coli CFT073 1040149 NP_752404.1 CDS c0470 NC_004431.1 459245 459931 R Residues 55 to 190 of 228 are 94.11 pct identical to residues 1 to 136 of 136 from MG1655 : b0364; hypothetical protein complement(459245..459931) Escherichia coli CFT073 1036213 NP_752405.1 CDS c0471 NC_004431.1 460376 460570 R hypothetical protein complement(460376..460570) Escherichia coli CFT073 1036197 NP_752406.3 CDS tauA NC_004431.1 460467 461486 D with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 460467..461486 Escherichia coli CFT073 1036201 NP_752407.1 CDS tauB NC_004431.1 461499 462266 D Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit 461499..462266 Escherichia coli CFT073 1036206 NP_752408.1 CDS c0474 NC_004431.1 461900 462214 R hypothetical protein complement(461900..462214) Escherichia coli CFT073 1036203 NP_752409.1 CDS tauC NC_004431.1 462263 463090 D Escherichia coli K-12 ortholog: b0367; Escherichia coli O157:H7 ortholog: z0466; taurine transporter subunit 462263..463090 Escherichia coli CFT073 1036195 NP_752410.1 CDS tauD NC_004431.1 463087 463938 D catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 463087..463938 Escherichia coli CFT073 1036193 NP_752411.1 CDS hemB NC_004431.1 463978 464985 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(463978..464985) Escherichia coli CFT073 1036196 NP_752412.1 CDS c0478 NC_004431.1 465478 468465 D Escherichia coli O157:H7 ortholog: z0469; SapA-like; structural protein 465478..468465 Escherichia coli CFT073 1036198 NP_752413.1 CDS yaiV NC_004431.1 468506 469174 D Escherichia coli K-12 ortholog: b0375; Escherichia coli O157:H7 ortholog: z0470; DNA-binding transcriptional regulator 468506..469174 Escherichia coli CFT073 1036185 NP_752414.1 CDS yaiH NC_004431.1 469175 470332 R this protein has no known enzymatic function; beta-lactam binding protein AmpH complement(469175..470332) Escherichia coli CFT073 1036189 NP_752415.1 CDS c0481 NC_004431.1 470470 470664 D hypothetical protein 470470..470664 Escherichia coli CFT073 1036184 NP_752416.1 CDS sbmA NC_004431.1 470678 471904 D in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transport protein 470678..471904 Escherichia coli CFT073 1036188 NP_752417.1 CDS yaiW NC_004431.1 471917 473011 D Escherichia coli K-12 ortholog: b0378; Escherichia coli O157:H7 ortholog: z0474; hypothetical protein 471917..473011 Escherichia coli CFT073 1036177 NP_752418.1 CDS yaiY NC_004431.1 473070 473378 R Escherichia coli K-12 ortholog: b0379; Escherichia coli O157:H7 ortholog: z0475; hypothetical protein complement(473070..473378) Escherichia coli CFT073 1036182 NP_752419.1 CDS c0485 NC_004431.1 473308 473442 D hypothetical protein 473308..473442 Escherichia coli CFT073 1036175 NP_752420.1 CDS yaiZ NC_004431.1 473506 473850 D Escherichia coli K-12 ortholog: b0380; Escherichia coli O157:H7 ortholog: z0476; hypothetical protein 473506..473850 Escherichia coli CFT073 1036183 NP_752421.1 CDS ddl NC_004431.1 473874 474968 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(473874..474968) Escherichia coli CFT073 1036174 NP_752422.1 CDS c0488 NC_004431.1 475046 475168 D hypothetical protein 475046..475168 Escherichia coli CFT073 1036169 NP_752423.1 CDS yaiB NC_004431.1 475431 475691 D Escherichia coli K-12 ortholog: b0382; Escherichia coli O157:H7 ortholog: z0478; hypothetical protein 475431..475691 Escherichia coli CFT073 1036178 NP_752424.1 CDS phoA NC_004431.1 475723 477207 D Escherichia coli K-12 ortholog: b0383; Escherichia coli O157:H7 ortholog: z0479; alkaline phosphatase 475723..477207 Escherichia coli CFT073 1036181 NP_752425.1 CDS psiF NC_004431.1 477308 477646 D Escherichia coli K-12 ortholog: b0384; Escherichia coli O157:H7 ortholog: z0480; hypothetical protein 477308..477646 Escherichia coli CFT073 1036168 NP_752426.1 CDS adrA NC_004431.1 477748 478863 D catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 477748..478863 Escherichia coli CFT073 1036170 NP_752427.3 CDS proC NC_004431.1 478880 479797 R catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase complement(478880..479797) Escherichia coli CFT073 1036167 NP_752429.1 CDS aroL NC_004431.1 480450 480974 D type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase II 480450..480974 Escherichia coli CFT073 1036156 NP_752430.1 CDS yaiA NC_004431.1 481024 481215 D Escherichia coli K-12 ortholog: b0389; Escherichia coli O157:H7 ortholog: z0485; hypothetical protein 481024..481215 Escherichia coli CFT073 1036164 NP_752431.1 CDS c0497 NC_004431.1 481406 481552 D hypothetical protein 481406..481552 Escherichia coli CFT073 1036163 NP_752432.1 CDS aroM NC_004431.1 481473 482150 D Escherichia coli K-12 ortholog: b0390; Escherichia coli O157:H7 ortholog: z0486; hypothetical protein 481473..482150 Escherichia coli CFT073 1036157 NP_752433.1 CDS yaiE NC_004431.1 482222 482506 D Escherichia coli K-12 ortholog: b0391; Escherichia coli O157:H7 ortholog: z0487; hypothetical protein 482222..482506 Escherichia coli CFT073 1034987 NP_752434.1 CDS c0500 NC_004431.1 482610 482765 R hypothetical protein complement(482610..482765) Escherichia coli CFT073 1036155 NP_752435.1 CDS ykiA NC_004431.1 482714 482995 D Escherichia coli K-12 ortholog: b0392; Escherichia coli O157:H7 ortholog: z0489; hypothetical protein 482714..482995 Escherichia coli CFT073 1036139 NP_752436.2 CDS rdgC NC_004431.1 483153 484064 R Required for efficient pilin antigenic variation; recombination associated protein complement(483153..484064) Escherichia coli CFT073 1036150 NP_752437.2 CDS c0503 NC_004431.1 484189 485097 D catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 484189..485097 Escherichia coli CFT073 1036134 NP_752438.1 CDS araJ NC_004431.1 485366 486634 R member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ complement(485366..486634) Escherichia coli CFT073 1036135 NP_752439.1 CDS sbcC NC_004431.1 486676 489819 R with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease SbcC complement(486676..489819) Escherichia coli CFT073 1036137 NP_752440.1 CDS sbcD NC_004431.1 489816 491018 R with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease SbcD complement(489816..491018) Escherichia coli CFT073 1036147 NP_752441.1 CDS c0507 NC_004431.1 491004 491135 D hypothetical protein 491004..491135 Escherichia coli CFT073 1036126 NP_752442.1 CDS phoB NC_004431.1 491208 491897 D two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB 491208..491897 Escherichia coli CFT073 1036128 NP_752443.1 CDS phoR NC_004431.1 491955 493250 D membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 491955..493250 Escherichia coli CFT073 1036130 NP_752444.1 CDS c0510 NC_004431.1 493463 493612 R hypothetical protein complement(493463..493612) Escherichia coli CFT073 1036119 NP_752445.1 CDS brnQ NC_004431.1 493657 494976 D LIV-II; Escherichia coli K-12 ortholog: b0401; Escherichia coli O157:H7 ortholog: z0499; branched chain amino acid ABC transporter carrier protein 493657..494976 Escherichia coli CFT073 1036122 NP_752446.1 CDS proY NC_004431.1 495049 496425 D cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; proline-specific permease 495049..496425 Escherichia coli CFT073 1036123 NP_752447.1 CDS malZ NC_004431.1 496581 498398 D Escherichia coli K-12 ortholog: b0403; Escherichia coli O157:H7 ortholog: z0501; maltodextrin glucosidase 496581..498398 Escherichia coli CFT073 1036127 NP_752448.2 CDS yajB NC_004431.1 498403 498984 R Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; ACP phosphodieterase complement(498403..498984) Escherichia coli CFT073 1036110 NP_752449.1 CDS queA NC_004431.1 499203 500273 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 499203..500273 Escherichia coli CFT073 1036106 NP_752450.1 CDS tgt NC_004431.1 500328 501455 D Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 500328..501455 Escherichia coli CFT073 1036109 NP_752451.2 CDS yajC NC_004431.1 501478 501810 D member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 501478..501810 Escherichia coli CFT073 1036111 NP_752452.1 CDS secD NC_004431.1 501838 503685 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 501838..503685 Escherichia coli CFT073 1036102 NP_752453.2 CDS secF NC_004431.1 503696 504667 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 503696..504667 Escherichia coli CFT073 1036099 NP_752454.1 CDS yajD NC_004431.1 504728 505144 D Escherichia coli K-12 ortholog: b0410; Escherichia coli O157:H7 ortholog: z0511; hypothetical protein 504728..505144 Escherichia coli CFT073 1036095 NP_752455.1 CDS tsx NC_004431.1 505182 506114 R Escherichia coli K-12 ortholog: b0411; Escherichia coli O157:H7 ortholog: z0512; nucleoside-specific channel-forming protein tsx complement(505182..506114) Escherichia coli CFT073 1036105 NP_752456.2 CDS yajI NC_004431.1 506365 506904 R Escherichia coli K-12 ortholog: b0412; Escherichia coli O157:H7 ortholog: z0513; hypothetical protein complement(506365..506904) Escherichia coli CFT073 1036097 NP_752457.1 CDS nrdR NC_004431.1 507055 507504 D Escherichia coli K-12 ortholog: b0413; Escherichia coli O157:H7 ortholog: z0514; transcriptional regulator NrdR 507055..507504 Escherichia coli CFT073 1036096 NP_752458.1 CDS ribD NC_004431.1 507508 508611 D riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 507508..508611 Escherichia coli CFT073 1036098 NP_752459.2 CDS ribH NC_004431.1 508700 509170 D RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 508700..509170 Escherichia coli CFT073 1036104 NP_752460.1 CDS c0526 NC_004431.1 509160 509693 R hypothetical protein complement(509160..509693) Escherichia coli CFT073 1036090 NP_752461.1 CDS nusB NC_004431.1 509190 509609 D Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 509190..509609 Escherichia coli CFT073 1036082 NP_752462.1 CDS thiL NC_004431.1 509687 510664 D catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 509687..510664 Escherichia coli CFT073 1036092 NP_752463.1 CDS pgpA NC_004431.1 510642 511160 D hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 510642..511160 Escherichia coli CFT073 1036086 NP_752464.1 CDS yajO NC_004431.1 511214 512188 R Escherichia coli K-12 ortholog: b0419; Escherichia coli O157:H7 ortholog: z0522; oxidoreductase yajO complement(511214..512188) Escherichia coli CFT073 1036083 NP_752465.1 CDS dxs NC_004431.1 512243 514105 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(512243..514105) Escherichia coli CFT073 1036087 NP_752466.1 CDS ispA NC_004431.1 514130 515029 R Escherichia coli K-12 ortholog: b0421; Escherichia coli O157:H7 ortholog: z0524; geranyltranstransferase complement(514130..515029) Escherichia coli CFT073 1036084 NP_752467.1 CDS xseB NC_004431.1 515029 515271 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(515029..515271) Escherichia coli CFT073 1036089 NP_752468.1 CDS yajK NC_004431.1 515477 516925 D Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 515477..516925 Escherichia coli CFT073 1036077 NP_752469.1 CDS thiJ NC_004431.1 516979 517575 R Escherichia coli K-12 ortholog: b0424; Escherichia coli O157:H7 ortholog: z0527; DJ-1 family protein complement(516979..517575) Escherichia coli CFT073 1036080 NP_752470.1 CDS apbA NC_004431.1 517532 518443 R ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase complement(517532..518443) Escherichia coli CFT073 1036079 NP_752471.2 CDS yajQ NC_004431.1 518611 519102 D nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 518611..519102 Escherichia coli CFT073 1036078 NP_752472.1 CDS yajR NC_004431.1 519230 520792 R Escherichia coli K-12 ortholog: b0427; Escherichia coli O157:H7 ortholog: z0530; transport protein YajR complement(519230..520792) Escherichia coli CFT073 1036067 NP_752473.1 CDS cyoE NC_004431.1 520743 521633 R converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase complement(520743..521633) Escherichia coli CFT073 1036068 NP_752474.1 CDS cyoD NC_004431.1 521645 521974 R Ubiquinol oxidase chain D; Escherichia coli K-12 ortholog: b0429; Escherichia coli O157:H7 ortholog: z0532; cytochrome o ubiquinol oxidase subunit IV complement(521645..521974) Escherichia coli CFT073 1036076 NP_752475.1 CDS cyoC NC_004431.1 521974 522588 R Escherichia coli K-12 ortholog: b0430; Escherichia coli O157:H7 ortholog: z0533; cytochrome o ubiquinol oxidase subunit III complement(521974..522588) Escherichia coli CFT073 1036073 NP_752476.1 CDS cyoB NC_004431.1 522578 524569 R Escherichia coli K-12 ortholog: b0431; Escherichia coli O157:H7 ortholog: z0534; cytochrome o ubiquinol oxidase subunit I complement(522578..524569) Escherichia coli CFT073 1036065 NP_752477.1 CDS cyoA NC_004431.1 524591 525538 R Escherichia coli K-12 ortholog: b0432; Escherichia coli O157:H7 ortholog: z0535; cytochrome o ubiquinol oxidase subunit II complement(524591..525538) Escherichia coli CFT073 1036056 NP_752478.1 CDS ampG NC_004431.1 525997 527472 R in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter complement(525997..527472) Escherichia coli CFT073 1036062 NP_752479.1 CDS c0545 NC_004431.1 527471 528070 D hypothetical protein 527471..528070 Escherichia coli CFT073 1036063 NP_752480.2 CDS yajG NC_004431.1 527516 528094 R Escherichia coli K-12 ortholog: b0434; Escherichia coli O157:H7 ortholog: z0537; hypothetical protein complement(527516..528094) Escherichia coli CFT073 1038095 NP_752481.1 CDS c0547 NC_004431.1 528144 528275 R hypothetical protein complement(528144..528275) Escherichia coli CFT073 1035864 NP_752482.2 CDS bolA NC_004431.1 528399 528716 D positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 528399..528716 Escherichia coli CFT073 1038029 NP_752483.1 CDS c0549 NC_004431.1 528643 529065 R hypothetical protein complement(528643..529065) Escherichia coli CFT073 1036060 NP_752484.1 CDS c0550 NC_004431.1 528725 528913 D hypothetical protein 528725..528913 Escherichia coli CFT073 1035216 NP_752485.1 CDS tig NC_004431.1 529060 530358 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 529060..530358 Escherichia coli CFT073 1035172 NP_752486.1 CDS c0552 NC_004431.1 529069 530370 R hypothetical protein complement(529069..530370) Escherichia coli CFT073 1035161 NP_752487.1 CDS clpP NC_004431.1 530604 531227 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 530604..531227 Escherichia coli CFT073 1035224 NP_752488.1 CDS clpX NC_004431.1 531353 532627 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 531353..532627 Escherichia coli CFT073 1039027 NP_752489.1 CDS lon NC_004431.1 532770 535169 D Escherichia coli K-12 ortholog: b0439; Escherichia coli O157:H7 ortholog: z0545; DNA-binding ATP-dependent protease La 532770..535169 Escherichia coli CFT073 1035203 NP_752490.1 CDS hupB NC_004431.1 535378 535650 D histone-like DNA-binding protein; transcriptional regulator HU subunit beta 535378..535650 Escherichia coli CFT073 1035227 NP_752491.1 CDS ybaU NC_004431.1 535842 537713 D Escherichia coli K-12 ortholog: b0441; Escherichia coli O157:H7 ortholog: z0548; peptidyl-prolyl cis-trans isomerase (rotamase D) 535842..537713 Escherichia coli CFT073 1040432 NP_752492.1 CDS ybaV NC_004431.1 537864 538235 D Escherichia coli K-12 ortholog: b0442; Escherichia coli O157:H7 ortholog: z0549; hypothetical protein 537864..538235 Escherichia coli CFT073 1035219 NP_752493.1 CDS ybaW NC_004431.1 538341 538739 D Escherichia coli K-12 ortholog: b0443; Escherichia coli O157:H7 ortholog: z0550; hypothetical protein 538341..538739 Escherichia coli CFT073 1036609 NP_752494.1 CDS ybaX NC_004431.1 538791 539486 R YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC complement(538791..539486) Escherichia coli CFT073 1035089 NP_752495.1 CDS ybaE NC_004431.1 539551 541266 R Escherichia coli K-12 ortholog: b0445; Escherichia coli O157:H7 ortholog: z0552; hypothetical protein complement(539551..541266) Escherichia coli CFT073 1035106 NP_752496.1 CDS cof NC_004431.1 541339 542169 D Escherichia coli K-12 ortholog: b0446; Escherichia coli O157:H7 ortholog: z0553; Cof protein 541339..542169 Escherichia coli CFT073 1035143 NP_752497.1 CDS c0563 NC_004431.1 542302 542811 D Residues 18 to 169 of 169 are 94.07 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein 542302..542811 Escherichia coli CFT073 1035736 NP_752498.1 CDS ybaO NC_004431.1 542925 543491 D Escherichia coli K-12 ortholog: b0447; Escherichia coli O157:H7 ortholog: z0555; transcriptional regulator YbaO 542925..543491 Escherichia coli CFT073 1034928 NP_752499.1 CDS mdlA NC_004431.1 543521 545293 D Escherichia coli K-12 ortholog: b0448; Escherichia coli O157:H7 ortholog: z0557; multidrug transporter membrane\ATP-binding components 543521..545293 Escherichia coli CFT073 1040487 NP_752500.2 CDS mdlB NC_004431.1 545286 547067 D Escherichia coli K-12 ortholog: b0449; Escherichia coli O157:H7 ortholog: z0559; multidrug transporter membrane\ATP-binding components 545286..547067 Escherichia coli CFT073 1040474 NP_752501.1 CDS c0567 NC_004431.1 547081 547221 R hypothetical protein complement(547081..547221) Escherichia coli CFT073 1034985 NP_752502.1 CDS glnK NC_004431.1 547248 547586 D indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 547248..547586 Escherichia coli CFT073 1036790 NP_752503.1 CDS c0569 NC_004431.1 547305 547538 R hypothetical protein complement(547305..547538) Escherichia coli CFT073 1040469 NP_752504.1 CDS amtB NC_004431.1 547616 548902 D Escherichia coli K-12 ortholog: b0451; Escherichia coli O157:H7 ortholog: z0563; ammonium transporter 547616..548902 Escherichia coli CFT073 1035428 NP_752505.1 CDS tesB NC_004431.1 548951 549895 R Escherichia coli K-12 ortholog: b0452; Escherichia coli O157:H7 ortholog: z0564; acyl-CoA thioesterase complement(548951..549895) Escherichia coli CFT073 1040477 NP_752506.1 CDS ybaY NC_004431.1 550029 550601 D Escherichia coli K-12 ortholog: b0453; Escherichia coli O157:H7 ortholog: z0565; hypothetical protein 550029..550601 Escherichia coli CFT073 1040420 NP_752507.1 CDS ybaZ NC_004431.1 550632 551042 R Escherichia coli K-12 ortholog: b0454; Escherichia coli O157:H7 ortholog: z0566; hypothetical protein complement(550632..551042) Escherichia coli CFT073 1039941 NP_752508.1 CDS ybaA NC_004431.1 551322 551675 D Escherichia coli K-12 ortholog: b0456; Escherichia coli O157:H7 ortholog: z0568; hypothetical protein 551322..551675 Escherichia coli CFT073 1035401 NP_752509.1 CDS ylaB NC_004431.1 551717 553273 R Escherichia coli K-12 ortholog: b0457; Escherichia coli O157:H7 ortholog: z0569; hypothetical protein complement(551717..553273) Escherichia coli CFT073 1036619 NP_752510.1 CDS ylaC NC_004431.1 553431 553940 R Escherichia coli K-12 ortholog: b0458; Escherichia coli O157:H7 ortholog: z0570; hypothetical protein complement(553431..553940) Escherichia coli CFT073 1040489 NP_752511.1 CDS ylaD NC_004431.1 554017 554568 R Escherichia coli K-12 ortholog: b0459; Escherichia coli O157:H7 ortholog: z0571; maltose O-acetyltransferase complement(554017..554568) Escherichia coli CFT073 1035420 NP_752512.1 CDS hha NC_004431.1 554741 554971 R with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein complement(554741..554971) Escherichia coli CFT073 1035413 NP_752513.1 CDS ybaJ NC_004431.1 554985 555359 R Escherichia coli K-12 ortholog: b0461; Escherichia coli O157:H7 ortholog: z0574; hypothetical protein complement(554985..555359) Escherichia coli CFT073 1039693 NP_752514.1 CDS acrB NC_004431.1 555904 559053 R Escherichia coli K-12 ortholog: b0462; Escherichia coli O157:H7 ortholog: z0576; acriflavin resistance protein B complement(555904..559053) Escherichia coli CFT073 1035438 NP_752515.1 CDS acrA NC_004431.1 559076 560305 R Escherichia coli K-12 ortholog: b0463; Escherichia coli O157:H7 ortholog: z0578; acriflavin resistance protein A complement(559076..560305) Escherichia coli CFT073 1035417 NP_752516.1 CDS acrR NC_004431.1 560411 561058 D regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 560411..561058 Escherichia coli CFT073 1035995 NP_752517.1 CDS c0583 NC_004431.1 561140 561304 D hypothetical protein 561140..561304 Escherichia coli CFT073 1035541 NP_752518.1 CDS aefA NC_004431.1 561186 564548 D small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 561186..564548 Escherichia coli CFT073 1035456 NP_752519.1 CDS ybaM NC_004431.1 564760 564921 R Escherichia coli K-12 ortholog: b0466; Escherichia coli O157:H7 ortholog: z0583; hypothetical protein complement(564760..564921) Escherichia coli CFT073 1035545 NP_752520.1 CDS priC NC_004431.1 564935 565462 R PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' complement(564935..565462) Escherichia coli CFT073 1035924 NP_752521.1 CDS ybaN NC_004431.1 565532 565909 D Escherichia coli K-12 ortholog: b0468; Escherichia coli O157:H7 ortholog: z0585; hypothetical protein 565532..565909 Escherichia coli CFT073 1035989 NP_752522.1 CDS apt NC_004431.1 566008 566613 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 566008..566613 Escherichia coli CFT073 1037590 NP_752523.1 CDS dnaX NC_004431.1 566742 568673 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 566742..568673 Escherichia coli CFT073 1036055 NP_752524.1 CDS c0590 NC_004431.1 568702 569079 R Residues 1 to 125 of 125 are 99.19 pct identical to residues 1 to 125 of 125 from GenPept.129 : >gb|AAB40225.1| (U82664) hypothetical protein [Escherichia coli]; hypothetical protein complement(568702..569079) Escherichia coli CFT073 1036011 NP_752525.1 CDS ybaB NC_004431.1 568711 569055 D Escherichia coli K-12 ortholog: b0471; Escherichia coli O157:H7 ortholog: z0588; hypothetical protein 568711..569055 Escherichia coli CFT073 1037598 NP_752526.1 CDS recR NC_004431.1 569055 569660 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 569055..569660 Escherichia coli CFT073 1036101 NP_752527.1 CDS htpG NC_004431.1 569770 571644 D molecular chaperone; heat shock protein 90 569770..571644 Escherichia coli CFT073 1037575 NP_752528.2 CDS adk NC_004431.1 571825 572469 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 571825..572469 Escherichia coli CFT073 1035723 NP_752529.1 CDS hemH NC_004431.1 572601 573563 D protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 572601..573563 Escherichia coli CFT073 1036165 NP_752530.1 CDS ybaC NC_004431.1 573560 574519 R Escherichia coli K-12 ortholog: b0476; Escherichia coli O157:H7 ortholog: z0593; acetyl esterase complement(573560..574519) Escherichia coli CFT073 1035679 NP_752531.1 CDS gsk NC_004431.1 574671 575975 D Escherichia coli K-12 ortholog: b0477; Escherichia coli O157:H7 ortholog: z0596; inosine-guanosine kinase 574671..575975 Escherichia coli CFT073 1036004 NP_752532.1 CDS ybaL NC_004431.1 576105 577781 R YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; cation:proton antiport protein complement(576105..577781) Escherichia coli CFT073 1038193 NP_752533.1 CDS fsr NC_004431.1 578019 579239 R Escherichia coli K-12 ortholog: b0479; Escherichia coli O157:H7 ortholog: z0598; fosmidomycin resistance protein complement(578019..579239) Escherichia coli CFT073 1040025 NP_752534.1 CDS ushA NC_004431.1 579457 581109 D catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 579457..581109 Escherichia coli CFT073 1038205 NP_752535.1 CDS ybaK NC_004431.1 581146 581625 R Escherichia coli K-12 ortholog: b0481; Escherichia coli O157:H7 ortholog: z0600; hypothetical protein complement(581146..581625) Escherichia coli CFT073 1036840 NP_752536.1 CDS ybaP NC_004431.1 581829 582623 R Escherichia coli K-12 ortholog: b0482; Escherichia coli O157:H7 ortholog: z0601; hypothetical protein complement(581829..582623) Escherichia coli CFT073 1036237 NP_752537.1 CDS ybaQ NC_004431.1 583093 583434 D Escherichia coli K-12 ortholog: b0483; Escherichia coli O157:H7 ortholog: z0602; hypothetical protein 583093..583434 Escherichia coli CFT073 1035360 NP_752538.1 CDS copA NC_004431.1 583492 585996 R Escherichia coli K-12 ortholog: b0484; Escherichia coli O157:H7 ortholog: z0604; copper exporting ATPase complement(583492..585996) Escherichia coli CFT073 1036268 NP_752539.1 CDS ybaS NC_004431.1 586259 587191 D catalyzes the formation of glutamate from glutamine; glutaminase 586259..587191 Escherichia coli CFT073 1036278 NP_752540.1 CDS ybaT NC_004431.1 587194 588486 D Escherichia coli K-12 ortholog: b0486; Escherichia coli O157:H7 ortholog: z0607; transport protein YbaT 587194..588486 Escherichia coli CFT073 1039634 NP_752541.1 CDS ybbI NC_004431.1 588611 589018 D activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 588611..589018 Escherichia coli CFT073 1038258 NP_752542.1 CDS c0608 NC_004431.1 589019 590242 R Residues 1 to 406 of 407 are 55.58 pct identical to residues 1 to 411 of 412 from GenPept.129 : >gb|AAL19611.1| (AE008726) cytoplasmic protein [Salmonella typhimurium LT2]; hypothetical protein complement(589019..590242) Escherichia coli CFT073 1036444 NP_752543.1 CDS ybbJ NC_004431.1 590361 590819 R Escherichia coli K-12 ortholog: b0488; Escherichia coli O157:H7 ortholog: z0641; hypothetical protein complement(590361..590819) Escherichia coli CFT073 1036276 NP_752544.1 CDS ybbK NC_004431.1 590816 591733 R Escherichia coli K-12 ortholog: b0489; Escherichia coli O157:H7 ortholog: z0642; hypothetical protein complement(590816..591733) Escherichia coli CFT073 1040282 NP_752545.1 CDS ybbL NC_004431.1 591876 592556 D Escherichia coli K-12 ortholog: b0490; Escherichia coli O157:H7 ortholog: z0643; ABC transporter ATP-binding protein YbbL 591876..592556 Escherichia coli CFT073 1035919 NP_752546.1 CDS ybbN NC_004431.1 593386 594276 R Escherichia coli K-12 ortholog: b0492; Escherichia coli O157:H7 ortholog: z0645; hypothetical protein complement(593386..594276) Escherichia coli CFT073 1040455 NP_752547.1 CDS ybbO NC_004431.1 594301 595110 R Escherichia coli K-12 ortholog: b0493; Escherichia coli O157:H7 ortholog: z0646; short chain dehydrogenase complement(594301..595110) Escherichia coli CFT073 1036368 NP_752548.1 CDS tesA NC_004431.1 595100 595756 R Escherichia coli K-12 ortholog: b0494; Escherichia coli O157:H7 ortholog: z0647; multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 complement(595100..595756) Escherichia coli CFT073 1036492 NP_752549.1 CDS ybbA NC_004431.1 595694 596380 D Escherichia coli K-12 ortholog: b0495; Escherichia coli O157:H7 ortholog: z0648; ABC transporter ATP-binding protein YbbA 595694..596380 Escherichia coli CFT073 1039534 NP_752550.1 CDS ybbP NC_004431.1 596377 598791 D Escherichia coli K-12 ortholog: b0496; Escherichia coli O157:H7 ortholog: z0649; hypothetical protein 596377..598791 Escherichia coli CFT073 1036171 NP_752551.1 CDS ybbB NC_004431.1 598942 599901 R catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase complement(598942..599901) Escherichia coli CFT073 1036042 NP_752552.1 CDS ybbS NC_004431.1 600096 601022 R activator of the allDC-ylbA operon involved in allantoin utilization; DNA-binding transcriptional activator AllS complement(600096..601022) Escherichia coli CFT073 1039678 NP_752553.1 CDS ybbT NC_004431.1 601252 601734 D catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 601252..601734 Escherichia coli CFT073 1036248 NP_752554.1 CDS ybbU NC_004431.1 601812 602627 D regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 601812..602627 Escherichia coli CFT073 1036274 NP_752555.2 CDS gcl NC_004431.1 602717 604498 D catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 602717..604498 Escherichia coli CFT073 1036035 NP_752556.1 CDS gip NC_004431.1 604511 605287 D Escherichia coli K-12 ortholog: b0508; Escherichia coli O157:H7 ortholog: z0662; hydroxypyruvate isomerase 604511..605287 Escherichia coli CFT073 1036160 NP_752557.1 CDS ybbQ NC_004431.1 605387 606265 D Escherichia coli K-12 ortholog: b0509; Escherichia coli O157:H7 ortholog: z0663; 2-hydroxy-3-oxopropionate reductase 605387..606265 Escherichia coli CFT073 1036046 NP_752558.1 CDS ybbW NC_004431.1 606435 607889 D Allantoin transport protein; Escherichia coli K-12 ortholog: b0511; Escherichia coli O157:H7 ortholog: z0665; allantoin permease 606435..607889 Escherichia coli CFT073 1036050 NP_752559.1 CDS ybbX NC_004431.1 607949 609310 D Plays a crucial role on both purine and pyrimidine metabolism; allantoinase 607949..609310 Escherichia coli CFT073 1036012 NP_752560.1 CDS ybbY NC_004431.1 609360 610667 D Escherichia coli K-12 ortholog: b0513; Escherichia coli O157:H7 ortholog: z0668; purine permease YbbY 609360..610667 Escherichia coli CFT073 1036037 NP_752561.1 CDS ybbZ NC_004431.1 610683 611834 D Escherichia coli K-12 ortholog: b0514; Escherichia coli O157:H7 ortholog: z0669; glycerate kinase II 610683..611834 Escherichia coli CFT073 1036043 NP_752562.1 CDS ylbA NC_004431.1 611963 612748 R Escherichia coli K-12 ortholog: b0515; Escherichia coli O157:H7 ortholog: z0670; hypothetical protein complement(611963..612748) Escherichia coli CFT073 1036034 NP_752563.1 CDS ylbB NC_004431.1 612759 614012 R allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase complement(612759..614012) Escherichia coli CFT073 1035999 NP_752564.1 CDS c0631 NC_004431.1 614016 615065 R Escherichia coli K-12 ortholog: b0517; Escherichia coli O157:H7 ortholog: z0672; ureidoglycolate dehydrogenase complement(614016..615065) Escherichia coli CFT073 1036000 NP_752565.1 CDS fdrA NC_004431.1 615382 617049 D multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 615382..617049 Escherichia coli CFT073 1036020 NP_752566.1 CDS ylbE NC_004431.1 617059 618318 D Escherichia coli K-12 ortholog: b0519; Escherichia coli O157:H7 ortholog: z0674; hypothetical protein 617059..618318 Escherichia coli CFT073 1036010 NP_752567.1 CDS ylbF NC_004431.1 618236 619144 D Escherichia coli K-12 ortholog: b0520; Escherichia coli O157:H7 ortholog: z0675; hypothetical protein 618236..619144 Escherichia coli CFT073 1039644 NP_752568.1 CDS arcC NC_004431.1 619141 620034 D forms a homodimer; may be used to synthesize carbomyl phosphate from ATP and carbamate; carbamate kinase 619141..620034 Escherichia coli CFT073 1035993 NP_752569.1 CDS purK NC_004431.1 620167 621234 R With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit complement(620167..621234) Escherichia coli CFT073 1035093 NP_752570.1 CDS purE NC_004431.1 621231 621767 R Catalyzes a step in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase catalytic subunit complement(621231..621767) Escherichia coli CFT073 1040159 NP_752571.1 CDS c0638 NC_004431.1 621836 622165 R hypothetical protein complement(621836..622165) Escherichia coli CFT073 1035965 NP_752572.1 CDS ybbF NC_004431.1 622276 622998 R catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase complement(622276..622998) Escherichia coli CFT073 1035968 NP_752573.1 CDS c0640 NC_004431.1 622989 623675 D Residues 1 to 228 of 228 are 96.49 pct identical to residues 1 to 228 of 228 from GenPept.129 : >gb|AAB40278.1| (U82664) hypothetical protein [Escherichia coli]; hypothetical protein 622989..623675 Escherichia coli CFT073 1035362 NP_752574.1 CDS ppiB NC_004431.1 623001 623495 R Escherichia coli K-12 ortholog: b0525; Escherichia coli O157:H7 ortholog: z0680; peptidyl-prolyl cis-trans isomerase B (rotamase B) complement(623001..623495) Escherichia coli CFT073 1038645 NP_752575.1 CDS cysS NC_004431.1 623669 625054 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 623669..625054 Escherichia coli CFT073 1040498 NP_752576.1 CDS ybcI NC_004431.1 625090 625527 R Escherichia coli K-12 ortholog: b0527; Escherichia coli O157:H7 ortholog: z0682; hypothetical protein complement(625090..625527) Escherichia coli CFT073 1035966 NP_752577.2 CDS ybcJ NC_004431.1 625720 625932 R Escherichia coli K-12 ortholog: b0528; Escherichia coli O157:H7 ortholog: z0683; hypothetical protein complement(625720..625932) Escherichia coli CFT073 1035957 NP_752578.1 CDS folD NC_004431.1 625934 626800 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(625934..626800) Escherichia coli CFT073 1035902 NP_752579.1 CDS c0646 NC_004431.1 626841 627038 D hypothetical protein 626841..627038 Escherichia coli CFT073 1038490 NP_752580.1 CDS ydfM NC_004431.1 627789 628145 D Escherichia coli K-12 ortholog: b1546; Escherichia coli O157:H7 ortholog: z1920; tail fiber assembly protein 627789..628145 Escherichia coli CFT073 1035946 NP_752581.1 CDS c0650 NC_004431.1 628118 628243 D hypothetical protein 628118..628243 Escherichia coli CFT073 1039654 NP_752582.1 CDS c0651 NC_004431.1 628200 628865 R Escherichia coli K-12 ortholog: b0562; Escherichia coli O157:H7 ortholog: z1925; hypothetical protein complement(628200..628865) Escherichia coli CFT073 1039676 NP_752583.1 CDS ompT NC_004431.1 629100 630053 R outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease complement(629100..630053) Escherichia coli CFT073 1035234 NP_752584.1 CDS ybcH NC_004431.1 630712 631602 R Escherichia coli K-12 ortholog: b0567; Escherichia coli O157:H7 ortholog: z0697; hypothetical protein complement(630712..631602) Escherichia coli CFT073 1035298 NP_752585.1 CDS nfrA NC_004431.1 631603 634596 R Escherichia coli K-12 ortholog: b0568; Escherichia coli O157:H7 ortholog: z0698; bacteriophage N4 receptor, outer membrane subunit complement(631603..634596) Escherichia coli CFT073 1040198 NP_752586.1 CDS nfrB NC_004431.1 634562 636724 R Escherichia coli K-12 ortholog: b0569; Escherichia coli O157:H7 ortholog: z0699; bacteriophage N4 adsorption protein B complement(634562..636724) Escherichia coli CFT073 1035290 NP_752587.1 CDS cusS NC_004431.1 636949 638391 R Escherichia coli K-12 ortholog: b0570; Escherichia coli O157:H7 ortholog: z0708; sensor kinase CusS complement(636949..638391) Escherichia coli CFT073 1039642 NP_752588.1 CDS cusR NC_004431.1 638381 639064 R response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR complement(638381..639064) Escherichia coli CFT073 1036802 NP_752589.1 CDS cusC NC_004431.1 639221 640603 D with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 639221..640603 Escherichia coli CFT073 1040042 NP_752590.1 CDS cusX NC_004431.1 640627 640959 D Escherichia coli K-12 ortholog: b0573; Escherichia coli O157:H7 ortholog: z0712; periplasmic copper-binding protein 640627..640959 Escherichia coli CFT073 1035280 NP_752591.1 CDS cusB NC_004431.1 640975 642198 D with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 640975..642198 Escherichia coli CFT073 1039714 NP_752592.1 CDS cusA NC_004431.1 642210 645353 D Escherichia coli K-12 ortholog: b0575; Escherichia coli O157:H7 ortholog: z0714; cation efflux system protein cusA 642210..645353 Escherichia coli CFT073 1035331 NP_752593.1 CDS pheP NC_004431.1 645419 646837 D Escherichia coli K-12 ortholog: b0576; Escherichia coli O157:H7 ortholog: z0715; phenylalanine transporter 645419..646837 Escherichia coli CFT073 1040425 NP_752594.1 CDS ybdG NC_004431.1 646994 648241 R Escherichia coli K-12 ortholog: b0577; Escherichia coli O157:H7 ortholog: z0716; hypothetical protein complement(646994..648241) Escherichia coli CFT073 1035315 NP_752595.1 CDS nfnB NC_004431.1 648349 649002 R catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase complement(648349..649002) Escherichia coli CFT073 1035082 NP_752596.1 CDS ybdF NC_004431.1 649081 649464 R Escherichia coli K-12 ortholog: b0579; Escherichia coli O157:H7 ortholog: z0718; hypothetical protein complement(649081..649464) Escherichia coli CFT073 1035655 NP_752597.1 CDS ybdJ NC_004431.1 649529 649777 R Escherichia coli K-12 ortholog: b0580; Escherichia coli O157:H7 ortholog: z0719; hypothetical protein complement(649529..649777) Escherichia coli CFT073 1034951 NP_752598.1 CDS ybdK NC_004431.1 649843 650961 R ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase complement(649843..650961) Escherichia coli CFT073 1040424 NP_752599.1 CDS entD NC_004431.1 651687 652457 R Escherichia coli K-12 ortholog: b0583; Escherichia coli O157:H7 ortholog: z0723; phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex complement(651687..652457) Escherichia coli CFT073 1035265 NP_752600.1 CDS fepA NC_004431.1 652482 654722 R Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA complement(652482..654722) Escherichia coli CFT073 1034981 NP_752601.1 CDS c0670 NC_004431.1 654715 654846 D hypothetical protein 654715..654846 Escherichia coli CFT073 1036685 NP_752602.1 CDS fes NC_004431.1 654965 656167 D Ferric enterobactin esterase; Escherichia coli K-12 ortholog: b0585; Escherichia coli O157:H7 ortholog: z0725; enterobactin/ferric enterobactin esterase 654965..656167 Escherichia coli CFT073 1035107 NP_752603.3 CDS c0672 NC_004431.1 656164 656388 D Escherichia coli O157:H7 ortholog: z0726; hypothetical protein 656164..656388 Escherichia coli CFT073 1035415 NP_752604.1 CDS entF NC_004431.1 656385 660266 D with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 656385..660266 Escherichia coli CFT073 1035086 NP_752605.1 CDS fepE NC_004431.1 660513 661646 D part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 660513..661646 Escherichia coli CFT073 1039935 NP_752606.1 CDS fepC NC_004431.1 661643 662458 R with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein complement(661643..662458) Escherichia coli CFT073 1035338 NP_752607.1 CDS fepG NC_004431.1 662455 663447 R with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease complement(662455..663447) Escherichia coli CFT073 1035293 NP_752608.1 CDS fepD NC_004431.1 663444 664460 R with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein complement(663444..664460) Escherichia coli CFT073 1035286 NP_752609.1 CDS ybdA NC_004431.1 664559 665809 D protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 664559..665809 Escherichia coli CFT073 1035393 NP_752610.1 CDS fepB NC_004431.1 665813 666769 R with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein complement(665813..666769) Escherichia coli CFT073 1035309 NP_752611.1 CDS entC NC_004431.1 666946 668133 D synthesizes isochorismate acid from chorismate; isochorismate synthase 666946..668133 Escherichia coli CFT073 1035606 NP_752612.1 CDS entE NC_004431.1 668143 669753 D bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 668143..669753 Escherichia coli CFT073 1035604 NP_752613.1 CDS entB NC_004431.1 669767 670624 D Escherichia coli K-12 ortholog: b0595; Escherichia coli O157:H7 ortholog: z0737; isochorismatase 669767..670624 Escherichia coli CFT073 1035596 NP_752614.1 CDS entA NC_004431.1 670624 671370 D catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 670624..671370 Escherichia coli CFT073 1035595 NP_752615.1 CDS ybdB NC_004431.1 671373 671786 D P15; Escherichia coli K-12 ortholog: b0597; Escherichia coli O157:H7 ortholog: z0739; hypothetical protein 671373..671786 Escherichia coli CFT073 1035608 NP_752616.1 CDS cstA NC_004431.1 671967 674072 D Escherichia coli K-12 ortholog: b0598; Escherichia coli O157:H7 ortholog: z0740; carbon starvation protein A 671967..674072 Escherichia coli CFT073 1035597 NP_752617.1 CDS c0686 NC_004431.1 674185 674382 D Escherichia coli K-12 ortholog: b4353; Escherichia coli O157:H7 ortholog: z5952; hypothetical protein 674185..674382 Escherichia coli CFT073 1035607 NP_752618.1 CDS ybdH NC_004431.1 674392 675480 R member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein complement(674392..675480) Escherichia coli CFT073 1035610 NP_752619.1 CDS ybdL NC_004431.1 675589 676749 D catalyzes the transfer of an amino moiety; aminotransferase 675589..676749 Escherichia coli CFT073 1035707 NP_752620.1 CDS c0689 NC_004431.1 676750 677379 R Escherichia coli K-12 ortholog: b0601; Escherichia coli O157:H7 ortholog: z0744; hypothetical protein complement(676750..677379) Escherichia coli CFT073 1035611 NP_752621.1 CDS c0690 NC_004431.1 677352 678572 R Escherichia coli K-12 ortholog: b0602; Escherichia coli O157:H7 ortholog: z0746; hypothetical protein complement(677352..678572) Escherichia coli CFT073 1035638 NP_752622.1 CDS ybdO NC_004431.1 678719 679657 R Escherichia coli K-12 ortholog: b0603; Escherichia coli O157:H7 ortholog: z0747; transcriptional regulator YbdO complement(678719..679657) Escherichia coli CFT073 1035717 NP_752623.3 CDS dsbG NC_004431.1 679826 680632 R Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase complement(679826..680632) Escherichia coli CFT073 1035712 NP_752624.1 CDS c0693 NC_004431.1 680911 681426 R hypothetical protein complement(680911..681426) Escherichia coli CFT073 1035746 NP_752625.1 CDS ahpC NC_004431.1 680944 681507 D with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase 680944..681507 Escherichia coli CFT073 1035753 NP_752626.1 CDS ahpF NC_004431.1 681648 683243 D Escherichia coli K-12 ortholog: b0606; Escherichia coli O157:H7 ortholog: z0750; alkyl hydroperoxide reductase 681648..683243 Escherichia coli CFT073 1035771 NP_752627.1 CDS ybdQ NC_004431.1 683364 683825 R Spots PR25/LM16/2D_000LR3; Escherichia coli K-12 ortholog: b0607; Escherichia coli O157:H7 ortholog: z0751; hypothetical protein complement(683364..683825) Escherichia coli CFT073 1036875 NP_752628.1 CDS c0697 NC_004431.1 684077 684460 D Escherichia coli K-12 ortholog: b0609; Escherichia coli O157:H7 ortholog: z0753; hypothetical protein 684077..684460 Escherichia coli CFT073 1035943 NP_752629.1 CDS rnk NC_004431.1 684149 684559 R Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator complement(684149..684559) Escherichia coli CFT073 1035714 NP_752630.1 CDS rna NC_004431.1 684789 685613 R Escherichia coli K-12 ortholog: b0611; Escherichia coli O157:H7 ortholog: z0755; ribonuclease I complement(684789..685613) Escherichia coli CFT073 1036052 NP_752631.1 CDS ybdS NC_004431.1 685709 687172 R Escherichia coli K-12 ortholog: b0612; Escherichia coli O157:H7 ortholog: z0756; citrate transporter complement(685709..687172) Escherichia coli CFT073 1035609 NP_752632.1 CDS citG NC_004431.1 687223 688101 R catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase complement(687223..688101) Escherichia coli CFT073 1040223 NP_752633.1 CDS citX NC_004431.1 688076 688627 R 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo- citrate lyase complement(688076..688627) Escherichia coli CFT073 1036335 NP_752634.1 CDS c0703 NC_004431.1 688595 689989 D hypothetical protein 688595..689989 Escherichia coli CFT073 1040288 NP_752635.1 CDS citF NC_004431.1 688631 690163 R Escherichia coli K-12 ortholog: b0615; Escherichia coli O157:H7 ortholog: z0759; citrate lyase subunit alpha complement(688631..690163) Escherichia coli CFT073 1036665 NP_752636.1 CDS c0705 NC_004431.1 690165 691211 D hypothetical protein 690165..691211 Escherichia coli CFT073 1036300 NP_752637.1 CDS citE NC_004431.1 690174 691097 R Escherichia coli K-12 ortholog: b0616; Escherichia coli O157:H7 ortholog: z0760; citrate lyase subunit beta complement(690174..691097) Escherichia coli CFT073 1035930 NP_752638.1 CDS citC NC_004431.1 691390 692397 R Escherichia coli K-12 ortholog: b0618; Escherichia coli O157:H7 ortholog: z0762; [citrate (pro-3S)-lyase] ligase complement(691390..692397) Escherichia coli CFT073 1036664 NP_752639.1 CDS citA NC_004431.1 692768 694486 D Escherichia coli K-12 ortholog: b0619; Escherichia coli O157:H7 ortholog: z0764; sensor kinase dpiB 692768..694486 Escherichia coli CFT073 1035932 NP_752640.1 CDS dpiA NC_004431.1 694455 695135 D regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 694455..695135 Escherichia coli CFT073 1036713 NP_752641.1 CDS dcuC NC_004431.1 695176 696561 R responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC complement(695176..696561) Escherichia coli CFT073 1036791 NP_752642.1 CDS pagP NC_004431.1 697148 697708 D catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 697148..697708 Escherichia coli CFT073 1036775 NP_752643.2 CDS cspE NC_004431.1 697883 698092 D member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 697883..698092 Escherichia coli CFT073 1036735 NP_752645.1 CDS ccrB NC_004431.1 698146 698529 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(698146..698529) Escherichia coli CFT073 1036678 NP_752646.1 CDS ybeM NC_004431.1 698616 699410 D Escherichia coli K-12 ortholog: b0626; Escherichia coli O157:H7 ortholog: z0771; amidase 698616..699410 Escherichia coli CFT073 1036877 NP_752647.1 CDS tatE NC_004431.1 699539 699742 D TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein E 699539..699742 Escherichia coli CFT073 1036793 NP_752648.1 CDS lipA NC_004431.1 699842 700807 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(699842..700807) Escherichia coli CFT073 1036894 NP_752649.1 CDS c0719 NC_004431.1 701039 701380 R Residues 61 to 111 of 114 are 98.00 pct identical to residues 72 to 124 of 321 from MG1655 : b0629; hypothetical protein complement(701039..701380) Escherichia coli CFT073 1036823 NP_752650.1 CDS lipB NC_004431.1 701627 702268 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(701627..702268) Escherichia coli CFT073 1036853 NP_752651.1 CDS ybeD NC_004431.1 702369 702632 R Escherichia coli K-12 ortholog: b0631; Escherichia coli O157:H7 ortholog: z0776; hypothetical protein complement(702369..702632) Escherichia coli CFT073 1036824 NP_752652.1 CDS dacA NC_004431.1 702742 703953 R penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase fraction A complement(702742..703953) Escherichia coli CFT073 1036908 NP_752653.1 CDS c0723 NC_004431.1 703991 704116 D hypothetical protein 703991..704116 Escherichia coli CFT073 1036933 NP_752654.1 CDS rlpA NC_004431.1 704093 705181 R Escherichia coli K-12 ortholog: b0633; Escherichia coli O157:H7 ortholog: z0778; rare lipoprotein A complement(704093..705181) Escherichia coli CFT073 1036857 NP_752655.1 CDS mrdB NC_004431.1 705192 706304 R Escherichia coli K-12 ortholog: b0634; Escherichia coli O157:H7 ortholog: z0780; cell wall shape-determining protein complement(705192..706304) Escherichia coli CFT073 1036902 NP_752656.1 CDS mrdA NC_004431.1 706307 708208 R PBP-2; Escherichia coli K-12 ortholog: b0635; Escherichia coli O157:H7 ortholog: z0781; penicillin-binding protein 2 complement(706307..708208) Escherichia coli CFT073 1037029 NP_752657.1 CDS ybeA NC_004431.1 708239 708706 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(708239..708706) Escherichia coli CFT073 1036966 NP_752658.1 CDS ybeB NC_004431.1 708710 709027 R Escherichia coli K-12 ortholog: b0637; Escherichia coli O157:H7 ortholog: z0783; hypothetical protein complement(708710..709027) Escherichia coli CFT073 1035925 NP_752659.1 CDS phpB NC_004431.1 709287 709901 R Escherichia coli K-12 ortholog: b0638; Escherichia coli O157:H7 ortholog: z0785; alpha-ribazole-5'-phosphate phosphatase complement(709287..709901) Escherichia coli CFT073 1037014 NP_752660.1 CDS nadD NC_004431.1 709922 710626 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase complement(709922..710626) Escherichia coli CFT073 1034961 NP_752661.1 CDS holA NC_004431.1 710565 711596 R required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta complement(710565..711596) Escherichia coli CFT073 1037044 NP_752662.1 CDS rlpB NC_004431.1 711596 712177 R rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB complement(711596..712177) Escherichia coli CFT073 1037058 NP_752663.1 CDS leuS NC_004431.1 712192 714915 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(712192..714915) Escherichia coli CFT073 1035928 NP_752664.1 CDS ybeL NC_004431.1 715009 715491 D Escherichia coli K-12 ortholog: b0643; Escherichia coli O157:H7 ortholog: z0790; hypothetical protein 715009..715491 Escherichia coli CFT073 1037141 NP_752665.2 CDS rihA NC_004431.1 715536 716471 R Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 complement(715536..716471) Escherichia coli CFT073 1037100 NP_752666.1 CDS gltL NC_004431.1 716589 717314 R Escherichia coli K-12 ortholog: b0652; Escherichia coli O157:H7 ortholog: z0802; glutamate/aspartate transport ATP-binding protein gltL complement(716589..717314) Escherichia coli CFT073 1037153 NP_752667.1 CDS gltK NC_004431.1 717314 717988 R Escherichia coli K-12 ortholog: b0653; Escherichia coli O157:H7 ortholog: z0803; glutamate/aspartate transport system permease gltK complement(717314..717988) Escherichia coli CFT073 1037092 NP_752668.1 CDS gltJ NC_004431.1 717988 718728 R Escherichia coli K-12 ortholog: b0654; Escherichia coli O157:H7 ortholog: z0804; glutamate/aspartate transport system permease gltJ complement(717988..718728) Escherichia coli CFT073 1035918 NP_752669.1 CDS ybeJ NC_004431.1 718898 719875 R Escherichia coli K-12 ortholog: b0655; Escherichia coli O157:H7 ortholog: z0805; glutamate and aspartate transporter subunit complement(718898..719875) Escherichia coli CFT073 1037265 NP_752670.1 CDS c0740 NC_004431.1 719941 720063 D hypothetical protein 719941..720063 Escherichia coli CFT073 1035926 NP_752671.1 CDS c0741 NC_004431.1 720260 722137 D Residues 15 to 253 of 625 are 35.54 pct identical to residues 22 to 275 of 281 from GenPept.129 : >gb|AAA61597.1| (L28755) 2'-N-acetyltransferase [Providencia stuartii]; hypothetical protein 720260..722137 Escherichia coli CFT073 1038156 NP_752672.1 CDS lnt NC_004431.1 722215 723753 R Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase complement(722215..723753) Escherichia coli CFT073 1038228 NP_752673.1 CDS ybeX NC_004431.1 723778 724656 R Escherichia coli K-12 ortholog: b0658; Escherichia coli O157:H7 ortholog: z0807; magnesium and cobalt efflux protein corC complement(723778..724656) Escherichia coli CFT073 1038236 NP_752674.1 CDS ybeY NC_004431.1 724746 725213 R Escherichia coli K-12 ortholog: b0659; Escherichia coli O157:H7 ortholog: z0808; metalloprotease complement(724746..725213) Escherichia coli CFT073 1038121 NP_752675.1 CDS ybeZ NC_004431.1 725210 726289 R Escherichia coli K-12 ortholog: b0660; Escherichia coli O157:H7 ortholog: z0809; PhoH-like protein complement(725210..726289) Escherichia coli CFT073 1038262 NP_752676.1 CDS c0746 NC_004431.1 726269 726412 D hypothetical protein 726269..726412 Escherichia coli CFT073 1038248 NP_752677.1 CDS yleA NC_004431.1 726403 727827 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(726403..727827) Escherichia coli CFT073 1038259 NP_752678.2 CDS ubiF NC_004431.1 727973 729148 D catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 727973..729148 Escherichia coli CFT073 1038240 NP_752679.2 CDS asnB NC_004431.1 730388 732052 R functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B complement(730388..732052) Escherichia coli CFT073 1035909 NP_752680.1 CDS nagD NC_004431.1 732308 733060 R Escherichia coli K-12 ortholog: b0675; Escherichia coli O157:H7 ortholog: z0822; UMP phosphatase complement(732308..733060) Escherichia coli CFT073 1040062 NP_752681.1 CDS nagC NC_004431.1 733108 734328 R Escherichia coli K-12 ortholog: b0676; Escherichia coli O157:H7 ortholog: z0823; N-acetylglucosamine repressor complement(733108..734328) Escherichia coli CFT073 1040199 NP_752682.1 CDS nagA NC_004431.1 734337 735485 R catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase complement(734337..735485) Escherichia coli CFT073 1040413 NP_752683.1 CDS nagB NC_004431.1 735545 736345 R catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase complement(735545..736345) Escherichia coli CFT073 1040280 NP_752684.1 CDS c0754 NC_004431.1 736394 736528 R hypothetical protein complement(736394..736528) Escherichia coli CFT073 1036036 NP_752685.1 CDS nagE NC_004431.1 736678 738624 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunits IIABC 736678..738624 Escherichia coli CFT073 1040298 NP_752686.1 CDS c0756 NC_004431.1 738594 738746 R hypothetical protein complement(738594..738746) Escherichia coli CFT073 1036580 NP_752687.1 CDS c0757 NC_004431.1 738713 739993 R Residues 1 to 425 of 426 are 26.49 pct identical to residues 27 to 447 of 450 from GenPept.129 : >emb|CAD07871.1| (AL627278) possible membrane transport protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein complement(738713..739993) Escherichia coli CFT073 1036410 NP_752688.1 CDS c0758 NC_004431.1 740007 740477 R Residues 1 to 149 of 156 are 36.00 pct identical to residues 1 to 147 of 150 from GenPept.129 : >emb|CAD06928.1| (AL627283) conserved hypothetical protein [Salmonella enterica subsp. enterica serovar Typhi]; hypthetical protein complement(740007..740477) Escherichia coli CFT073 1039933 NP_752689.1 CDS c0759 NC_004431.1 740474 741643 R Residues 3 to 385 of 389 are 46.78 pct identical to residues 6 to 391 of 396 from GenPept.129 : >gb|AAL45764.1| (AE008932) conserved hypothetical protein [Agrobacterium tumefaciens str. C58 (U. Washington)]; hypthetical protein complement(740474..741643) Escherichia coli CFT073 1035352 NP_752690.1 CDS c0760 NC_004431.1 741679 742437 R Escherichia coli K-12 ortholog: b2832; Escherichia coli O157:H7 ortholog: z4150; hypothetical protein complement(741679..742437) Escherichia coli CFT073 1035617 NP_752691.1 CDS c0761 NC_004431.1 742497 743384 R Residues 11 to 294 of 295 are 43.50 pct identical to residues 8 to 292 of 297 from GenPept.129 : >gb|AAL45759.1| (AE008931) dihydrodipicolinate synthase [Agrobacterium tumefaciens str. C58 (U. Washington)]; dihydrodipicolinate synthase complement(742497..743384) Escherichia coli CFT073 1035207 NP_752692.1 CDS c0762 NC_004431.1 743388 744545 R Residues 11 to 378 of 385 are 33.87 pct identical to residues 33 to 399 of 399 from GenPept.129 : >gb|AAL13074.2| (AY052389) AttL [Agrobacterium tumefaciens]; alcohol dehydrogenase complement(743388..744545) Escherichia coli CFT073 1035126 NP_752693.1 CDS c0763 NC_004431.1 744820 745950 D Residues 11 to 372 of 376 are 40.21 pct identical to residues 41 to 418 of 423 from GenPept.129 : >gb|AAL19126.1| (AE008701) inner membrane protein [Salmonella typhimurium LT2]; inner membrane protein 744820..745950 Escherichia coli CFT073 1035961 NP_752694.1 CDS pdxA NC_004431.1 745943 746929 D catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 745943..746929 Escherichia coli CFT073 1035397 NP_752695.1 CDS c0765 NC_004431.1 746931 747692 D LysR family; Residues 1 to 234 of 253 are 70.08 pct identical to residues 1 to 234 of 255 from GenPept.129 : >gb|AAL19128.1| (AE008701) transcriptional regulator (LysR family) [Salmonella typhimurium LT2]; transcriptional regulator 746931..747692 Escherichia coli CFT073 1035396 NP_752696.1 CDS glnS NC_004431.1 747912 749576 D catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 747912..749576 Escherichia coli CFT073 1040092 NP_752697.1 CDS c0767 NC_004431.1 749807 750265 D Residues 1 to 152 of 152 are 94.07 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein 749807..750265 Escherichia coli CFT073 1035950 NP_752698.1 CDS ybfM NC_004431.1 750730 752136 D Escherichia coli K-12 ortholog: b0681; Escherichia coli O157:H7 ortholog: z0829; hypothetical protein 750730..752136 Escherichia coli CFT073 1036235 NP_752699.1 CDS ybfN NC_004431.1 752186 752512 D Escherichia coli K-12 ortholog: b0682; Escherichia coli O157:H7 ortholog: z0830; lipoprotein ybfN 752186..752512 Escherichia coli CFT073 1038176 NP_752700.1 CDS fur NC_004431.1 752596 753042 R negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator complement(752596..753042) Escherichia coli CFT073 1037658 NP_752701.2 CDS fldA NC_004431.1 753331 753861 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA complement(753331..753861) Escherichia coli CFT073 1035998 NP_752702.1 CDS ybfE NC_004431.1 754001 754363 R Escherichia coli K-12 ortholog: b0685; Escherichia coli O157:H7 ortholog: z0834; LexA regulated protein complement(754001..754363) Escherichia coli CFT073 1035980 NP_752703.1 CDS ybfF NC_004431.1 754434 755198 R Escherichia coli K-12 ortholog: b0686; Escherichia coli O157:H7 ortholog: z0835; hypothetical protein complement(754434..755198) Escherichia coli CFT073 1037693 NP_752704.2 CDS seqA NC_004431.1 755383 755928 D negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 755383..755928 Escherichia coli CFT073 1036013 NP_752705.1 CDS pgm NC_004431.1 755903 757594 D catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 755903..757594 Escherichia coli CFT073 1036333 NP_752706.1 CDS potE NC_004431.1 757651 758970 R catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter complement(757651..758970) Escherichia coli CFT073 1036030 NP_752707.1 CDS speF NC_004431.1 758967 761174 R Escherichia coli K-12 ortholog: b0693; Escherichia coli O157:H7 ortholog: z0839; ornithine decarboxylase complement(758967..761174) Escherichia coli CFT073 1036141 NP_752708.1 CDS c0778 NC_004431.1 761179 761331 R hypothetical protein complement(761179..761331) Escherichia coli CFT073 1036943 NP_752709.1 CDS kdpE NC_004431.1 761791 762468 R response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE complement(761791..762468) Escherichia coli CFT073 1035398 NP_752710.1 CDS kdpD NC_004431.1 762465 765152 R sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD complement(762465..765152) Escherichia coli CFT073 1035720 NP_752711.1 CDS kdpC NC_004431.1 765142 765738 R One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C complement(765142..765738) Escherichia coli CFT073 1036279 NP_752712.1 CDS kdpB NC_004431.1 765723 767771 R One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B complement(765723..767771) Escherichia coli CFT073 1035814 NP_752713.1 CDS kdpA NC_004431.1 767794 769467 R catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A complement(767794..769467) Escherichia coli CFT073 1036015 NP_752714.1 CDS c0784 NC_004431.1 769467 769670 R Residues 39 to 67 of 67 are 93.10 pct identical to residues 1 to 29 of 29 from GenPept.129 : >dbj|BAA35357.1| (D90709) KdpF protein. [Escherichia coli]; hypothetical protein complement(769467..769670) Escherichia coli CFT073 1035605 NP_752715.1 CDS ybfA NC_004431.1 769869 770075 D Escherichia coli K-12 ortholog: b0699; Escherichia coli O157:H7 ortholog: z0846; hypothetical protein 769869..770075 Escherichia coli CFT073 1036018 NP_752716.1 CDS ybgA NC_004431.1 770176 770685 D TKP; Escherichia coli K-12 ortholog: b0707; Escherichia coli O157:H7 ortholog: z0858; hypothetical protein 770176..770685 Escherichia coli CFT073 1036722 NP_752717.1 CDS phrB NC_004431.1 770682 772100 D UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 770682..772100 Escherichia coli CFT073 1035982 NP_752718.1 CDS ybgH NC_004431.1 772142 773623 R Escherichia coli K-12 ortholog: b0709; Escherichia coli O157:H7 ortholog: z0860; transporter YbgH complement(772142..773623) Escherichia coli CFT073 1036919 NP_752719.1 CDS ybgI NC_004431.1 773894 774637 D Escherichia coli K-12 ortholog: b0710; Escherichia coli O157:H7 ortholog: z0861; hydrolase-oxidase 773894..774637 Escherichia coli CFT073 1036967 NP_752720.1 CDS ybgJ NC_004431.1 774660 775316 D Escherichia coli K-12 ortholog: b0711; Escherichia coli O157:H7 ortholog: z0862; hypothetical protein 774660..775316 Escherichia coli CFT073 1035996 NP_752721.1 CDS ybgK NC_004431.1 775310 776242 D Escherichia coli K-12 ortholog: b0712; Escherichia coli O157:H7 ortholog: z0863; hypothetical protein 775310..776242 Escherichia coli CFT073 1035978 NP_752722.1 CDS ybgL NC_004431.1 776232 776966 D Escherichia coli K-12 ortholog: b0713; Escherichia coli O157:H7 ortholog: z0864; LamB/YcsF family protein 776232..776966 Escherichia coli CFT073 1036862 NP_752723.1 CDS nei NC_004431.1 777002 777793 D 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity; endonuclease VIII 777002..777793 Escherichia coli CFT073 1035763 NP_752724.1 CDS abrB NC_004431.1 777790 778881 R AidB regulator; Escherichia coli K-12 ortholog: b0715; Escherichia coli O157:H7 ortholog: z0867; AbrB protein complement(777790..778881) Escherichia coli CFT073 1036844 NP_752725.1 CDS c0795 NC_004431.1 779120 779362 R Residues 1 to 80 of 80 are 94.99 pct identical to residues 239 to 318 of 362 from MG1655 : b0716; hypothetical protein complement(779120..779362) Escherichia coli CFT073 1040361 NP_752726.1 CDS gltA NC_004431.1 779510 780793 R type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase complement(779510..780793) Escherichia coli CFT073 1036856 NP_752727.1 CDS c0797 NC_004431.1 780775 780966 D Residues 27 to 63 of 63 are 67.56 pct identical to residues 2 to 38 of 81 from GenPept.129 : >emb|CAD05193.1| (AL627268) hypothetical protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein 780775..780966 Escherichia coli CFT073 1035346 NP_752728.2 CDS sdhC NC_004431.1 781502 781891 D Escherichia coli K-12 ortholog: b0721; Escherichia coli O157:H7 ortholog: z0875; succinate dehydrogenase cytochrome b556 large membrane subunit 781502..781891 Escherichia coli CFT073 1036744 NP_752729.1 CDS c0799 NC_004431.1 781544 781774 R hypothetical protein complement(781544..781774) Escherichia coli CFT073 1039949 NP_752730.1 CDS sdhD NC_004431.1 781885 782232 D Escherichia coli K-12 ortholog: b0722; Escherichia coli O157:H7 ortholog: z0876; succinate dehydrogenase cytochrome b556 small membrane subunit 781885..782232 Escherichia coli CFT073 1039528 NP_752731.2 CDS sdhA NC_004431.1 782232 783998 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 782232..783998 Escherichia coli CFT073 1039505 NP_752732.1 CDS sdhB NC_004431.1 784014 784730 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 784014..784730 Escherichia coli CFT073 1040343 NP_752733.1 CDS sucA NC_004431.1 785281 788082 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 785281..788082 Escherichia coli CFT073 1035834 NP_752734.1 CDS sucB NC_004431.1 788097 789314 D component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 788097..789314 Escherichia coli CFT073 1036634 NP_752735.1 CDS sucC NC_004431.1 789408 790574 D catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 789408..790574 Escherichia coli CFT073 1039366 NP_752736.1 CDS sucD NC_004431.1 790574 791443 D Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 790574..791443 Escherichia coli CFT073 1040403 NP_752737.1 CDS c0807 NC_004431.1 791683 792642 D Residues 16 to 223 of 319 are 32.74 pct identical to residues 1594 to 1812 of 1819 from GenPept.129 : >gb|AAK79055.1|AE007624_2 (AE007624) Uncharacterized protein, probably surface-located [Clostridium acetobutylicum]; hypothetical protein 791683..792642 Escherichia coli CFT073 1039950 NP_752738.1 CDS c0808 NC_004431.1 792671 793024 D hypothetical protein 792671..793024 Escherichia coli CFT073 1040334 NP_752739.1 CDS c0809 NC_004431.1 793092 793214 R hypothetical protein complement(793092..793214) Escherichia coli CFT073 1035835 NP_752740.1 CDS c0810 NC_004431.1 793232 793378 R hypothetical protein complement(793232..793378) Escherichia coli CFT073 1039140 NP_752741.1 CDS cydA NC_004431.1 794125 795696 D Escherichia coli K-12 ortholog: b0733; Escherichia coli O157:H7 ortholog: z0900; cytochrome D ubiquinol oxidase subunit I 794125..795696 Escherichia coli CFT073 1035833 NP_752742.1 CDS cydB NC_004431.1 795712 796851 D Escherichia coli K-12 ortholog: b0734; Escherichia coli O157:H7 ortholog: z0901; cytochrome D ubiquinol oxidase subunit II 795712..796851 Escherichia coli CFT073 1038924 NP_752743.1 CDS c0813 NC_004431.1 795766 796881 R hypothetical protein complement(795766..796881) Escherichia coli CFT073 1039020 NP_752744.1 CDS ybgE NC_004431.1 796979 797272 D Escherichia coli K-12 ortholog: b0735; Escherichia coli O157:H7 ortholog: z0903; hypothetical protein 796979..797272 Escherichia coli CFT073 1039436 NP_752745.1 CDS ybgC NC_004431.1 797422 797826 D catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase 797422..797826 Escherichia coli CFT073 1039037 NP_752746.1 CDS tolQ NC_004431.1 797823 798515 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 797823..798515 Escherichia coli CFT073 1039008 NP_752747.1 CDS tolR NC_004431.1 798519 798947 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 798519..798947 Escherichia coli CFT073 1038834 NP_752748.1 CDS tolA NC_004431.1 799012 800277 D inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 799012..800277 Escherichia coli CFT073 1039041 NP_752749.1 CDS tolB NC_004431.1 800407 801702 D forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 800407..801702 Escherichia coli CFT073 1038911 NP_752750.1 CDS c0820 NC_004431.1 801671 802291 R hypothetical protein complement(801671..802291) Escherichia coli CFT073 1038903 NP_752751.1 CDS pal NC_004431.1 801713 802258 D Escherichia coli K-12 ortholog: b0741; Escherichia coli O157:H7 ortholog: z0909; peptidoglycan-associated outer membrane lipoprotein 801713..802258 Escherichia coli CFT073 1038851 NP_752752.1 CDS ybgF NC_004431.1 802268 802933 D Escherichia coli K-12 ortholog: b0742; Escherichia coli O157:H7 ortholog: z0910; hypothetical protein 802268..802933 Escherichia coli CFT073 1036640 NP_752753.1 CDS c0823 NC_004431.1 802857 803060 D Residues 5 to 67 of 67 are 100.00 pct identical to residues 201 to 263 of 263 from MG1655 : b0742; hypothetical protein 802857..803060 Escherichia coli CFT073 1038672 NP_752754.1 CDS c0824 NC_004431.1 802905 803204 R hypothetical protein complement(802905..803204) Escherichia coli CFT073 1038817 NP_752755.1 CDS nadA NC_004431.1 804206 805249 D 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 804206..805249 Escherichia coli CFT073 1039955 NP_752756.1 CDS pnuC NC_004431.1 805287 806006 D Escherichia coli K-12 ortholog: b0751; Escherichia coli O157:H7 ortholog: z0920; protein pnuC 805287..806006 Escherichia coli CFT073 1038277 NP_752757.1 CDS c0827 NC_004431.1 806003 806401 R Residues 10 to 132 of 132 are 98.37 pct identical to residues 191 to 313 of 313 from MG1655 : b0752; hypothetical protein complement(806003..806401) Escherichia coli CFT073 1038410 NP_752758.1 CDS c0828 NC_004431.1 806488 806919 D hypothetical protein 806488..806919 Escherichia coli CFT073 1038646 NP_752759.1 CDS ybgS NC_004431.1 806505 806885 R Escherichia coli K-12 ortholog: b0753; Escherichia coli O157:H7 ortholog: z0923; hypothetical protein complement(806505..806885) Escherichia coli CFT073 1038488 NP_752760.1 CDS aroG NC_004431.1 807201 808253 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 807201..808253 Escherichia coli CFT073 1038119 NP_752761.1 CDS gpmA NC_004431.1 808419 809186 R 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase complement(808419..809186) Escherichia coli CFT073 1037999 NP_752762.1 CDS galM NC_004431.1 809374 810414 R catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase complement(809374..810414) Escherichia coli CFT073 1038053 NP_752763.1 CDS galK NC_004431.1 810408 811556 R catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase complement(810408..811556) Escherichia coli CFT073 1038288 NP_752764.1 CDS galT NC_004431.1 811560 812606 R catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase complement(811560..812606) Escherichia coli CFT073 1037875 NP_752765.1 CDS galE NC_004431.1 812616 813632 R Escherichia coli K-12 ortholog: b0759; Escherichia coli O157:H7 ortholog: z0929; UDP-galactose-4-epimerase complement(812616..813632) Escherichia coli CFT073 1036650 NP_752766.2 CDS modF NC_004431.1 813894 815366 R contains 2 ATP-binding cassettes; involved in the transport of molybdenum; molybdenum transport ATP-binding protein ModF complement(813894..815366) Escherichia coli CFT073 1037980 NP_752767.1 CDS modE NC_004431.1 815434 816222 R represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE complement(815434..816222) Escherichia coli CFT073 1039959 NP_752768.1 CDS ybhT NC_004431.1 816345 816500 D Escherichia coli K-12 ortholog: b0762; Escherichia coli O157:H7 ortholog: z0932; hypothetical protein 816345..816500 Escherichia coli CFT073 1038066 NP_752769.1 CDS c0839 NC_004431.1 816436 816645 D hypothetical protein 816436..816645 Escherichia coli CFT073 1037847 NP_752770.1 CDS modA NC_004431.1 816667 817440 D with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 816667..817440 Escherichia coli CFT073 1037955 NP_752771.1 CDS modB NC_004431.1 817440 818129 D part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 817440..818129 Escherichia coli CFT073 1037798 NP_752772.1 CDS modC NC_004431.1 818132 819190 D Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 818132..819190 Escherichia coli CFT073 1037777 NP_752773.1 CDS ybhA NC_004431.1 819191 820009 R YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase complement(819191..820009) Escherichia coli CFT073 1037728 NP_752774.1 CDS ybhE NC_004431.1 820164 821159 D catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 820164..821159 Escherichia coli CFT073 1035826 NP_752775.1 CDS ybhD NC_004431.1 821200 822216 R Escherichia coli K-12 ortholog: b0768; Escherichia coli O157:H7 ortholog: z0939; transcriptional regulator YbhD complement(821200..822216) Escherichia coli CFT073 1037699 NP_752776.1 CDS ybhH NC_004431.1 822337 823389 D Escherichia coli K-12 ortholog: b0769; Escherichia coli O157:H7 ortholog: z0940; hypothetical protein 822337..823389 Escherichia coli CFT073 1035824 NP_752777.1 CDS ybhI NC_004431.1 823465 824898 D Escherichia coli K-12 ortholog: b0770; Escherichia coli O157:H7 ortholog: z0941; hypothetical protein 823465..824898 Escherichia coli CFT073 1036654 NP_752778.2 CDS ybhJ NC_004431.1 825081 827342 D Escherichia coli K-12 ortholog: b0771; Escherichia coli O157:H7 ortholog: z0942; hypothetical protein 825081..827342 Escherichia coli CFT073 1038048 NP_752779.1 CDS ybhC NC_004431.1 827482 828765 R outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family; pectinesterase complement(827482..828765) Escherichia coli CFT073 1037715 NP_752780.1 CDS ybhB NC_004431.1 828917 829393 R YbhB; similar to rat and human kinase inhibitory proteins; kinase inhibitor protein complement(828917..829393) Escherichia coli CFT073 1035822 NP_752781.1 CDS gipA NC_004431.1 829502 830632 D Residues 1 to 373 of 376 are 54.52 pct identical to residues 5 to 379 of 402 from SwissProt.40 : >sp|P54992|YSNA_STRPR Hypothetical 45.4 kDa protein in SNAA-SNAB intergenic region (ORF401); Peyer's patch-specific virulence factor GipA 829502..830632 Escherichia coli CFT073 1037757 NP_752782.1 CDS c0852 NC_004431.1 829652 829858 R hypothetical protein complement(829652..829858) Escherichia coli CFT073 1037735 NP_752783.2 CDS bioA NC_004431.1 830743 832032 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase complement(830743..832032) Escherichia coli CFT073 1037742 NP_752784.1 CDS c0854 NC_004431.1 830809 831006 D hypothetical protein 830809..831006 Escherichia coli CFT073 1037705 NP_752785.1 CDS bioB NC_004431.1 832119 833159 D Escherichia coli K-12 ortholog: b0775; Escherichia coli O157:H7 ortholog: z0994; biotin synthase 832119..833159 Escherichia coli CFT073 1037718 NP_752786.1 CDS bioF NC_004431.1 833156 834310 D catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 833156..834310 Escherichia coli CFT073 1039962 NP_752788.1 CDS bioD NC_004431.1 835045 835722 D DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 835045..835722 Escherichia coli CFT073 1036660 NP_752789.1 CDS c0859 NC_004431.1 835889 836026 R hypothetical protein complement(835889..836026) Escherichia coli CFT073 1037741 NP_752790.1 CDS uvrB NC_004431.1 836301 838322 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 836301..838322 Escherichia coli CFT073 1037760 NP_752791.1 CDS ybhK NC_004431.1 838360 839328 R Escherichia coli K-12 ortholog: b0780; Escherichia coli O157:H7 ortholog: z0999; hypothetical protein complement(838360..839328) Escherichia coli CFT073 1037727 NP_752792.1 CDS moaA NC_004431.1 839584 840654 D together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 839584..840654 Escherichia coli CFT073 1036662 NP_752793.1 CDS moaB NC_004431.1 840676 841188 D Escherichia coli K-12 ortholog: b0782; Escherichia coli O157:H7 ortholog: z1001; molybdenum cofactor biosynthesis protein B 840676..841188 Escherichia coli CFT073 1037746 NP_752794.1 CDS c0864 NC_004431.1 840930 841421 R hypothetical protein complement(840930..841421) Escherichia coli CFT073 1037755 NP_752795.1 CDS moaC NC_004431.1 841191 841676 D MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 841191..841676 Escherichia coli CFT073 1040472 NP_752796.2 CDS moaD NC_004431.1 841669 841914 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 841669..841914 Escherichia coli CFT073 1037756 NP_752797.1 CDS moaE NC_004431.1 841916 842368 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 841916..842368 Escherichia coli CFT073 1037772 NP_752798.1 CDS ybhL NC_004431.1 842424 843209 D Escherichia coli K-12 ortholog: b0786; Escherichia coli O157:H7 ortholog: z1005; hypothetical protein 842424..843209 Escherichia coli CFT073 1037790 NP_752799.1 CDS c0869 NC_004431.1 843141 843272 R Residues 6 to 43 of 43 are 94.73 pct identical to residues 8 to 45 of 45 from GenPept.129 : >dbj|BAA35445.1| (D90716) ORF_ID:o203#8 [Escherichia coli]; hypothetical protein complement(843141..843272) Escherichia coli CFT073 1037796 NP_752800.1 CDS ybhM NC_004431.1 843388 844128 D Escherichia coli K-12 ortholog: b0787; Escherichia coli O157:H7 ortholog: z1006; hypothetical protein 843388..844128 Escherichia coli CFT073 1037773 NP_752801.1 CDS ybhN NC_004431.1 844164 845120 R Escherichia coli K-12 ortholog: b0788; Escherichia coli O157:H7 ortholog: z1007; hypothetical protein complement(844164..845120) Escherichia coli CFT073 1037771 NP_752802.1 CDS ybhO NC_004431.1 845120 846361 R Escherichia coli K-12 ortholog: b0789; Escherichia coli O157:H7 ortholog: z1008; cardiolipin synthase 2 complement(845120..846361) Escherichia coli CFT073 1037779 NP_752803.1 CDS ybhP NC_004431.1 846358 847119 R Escherichia coli K-12 ortholog: b0790; Escherichia coli O157:H7 ortholog: z1009; hypothetical protein complement(846358..847119) Escherichia coli CFT073 1037799 NP_752804.1 CDS ybhQ NC_004431.1 847252 847662 D Escherichia coli K-12 ortholog: b0791; Escherichia coli O157:H7 ortholog: z1010; hypothetical protein 847252..847662 Escherichia coli CFT073 1037805 NP_752805.1 CDS ybhR NC_004431.1 847624 848730 R Escherichia coli K-12 ortholog: b0792; Escherichia coli O157:H7 ortholog: z1012; hypothetical protein complement(847624..848730) Escherichia coli CFT073 1035809 NP_752806.1 CDS ybhS NC_004431.1 848741 849874 R Escherichia coli K-12 ortholog: b0793; Escherichia coli O157:H7 ortholog: z1013; hypothetical protein complement(848741..849874) Escherichia coli CFT073 1037834 NP_752807.1 CDS ybhF NC_004431.1 849867 851618 R Escherichia coli K-12 ortholog: b0794; Escherichia coli O157:H7 ortholog: z1014; ABC transporter ATP-binding protein complement(849867..851618) Escherichia coli CFT073 1035802 NP_752808.1 CDS ybhG NC_004431.1 851596 852594 R Escherichia coli K-12 ortholog: b0795; Escherichia coli O157:H7 ortholog: z1015; hypothetical protein complement(851596..852594) Escherichia coli CFT073 1037815 NP_752809.1 CDS ybiH NC_004431.1 852594 853277 R Escherichia coli K-12 ortholog: b0796; Escherichia coli O157:H7 ortholog: z1016; DNA-binding transcriptional regulator complement(852594..853277) Escherichia coli CFT073 1037808 NP_752810.1 CDS rhlE NC_004431.1 853494 854855 D this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 853494..854855 Escherichia coli CFT073 1037845 YP_004853797.1 CDS c0881 NC_004431.1 854932 855072 R hypothetical protein complement(854932..855072) Escherichia coli CFT073 1036691 NP_752812.1 CDS c0882 NC_004431.1 855088 855393 R Residues 32 to 101 of 101 are 80.00 pct identical to residues 91 to 160 of 160 from MG1655 : b0798; hypothetical protein complement(855088..855393) Escherichia coli CFT073 1035803 NP_752813.1 CDS dinG NC_004431.1 855392 857542 D helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 855392..857542 Escherichia coli CFT073 1037800 NP_752814.1 CDS ybiB NC_004431.1 857570 858532 D Escherichia coli K-12 ortholog: b0800; Escherichia coli O157:H7 ortholog: z1021; glycosyl transferase family protein 857570..858532 Escherichia coli CFT073 1037851 NP_752815.1 CDS ybiC NC_004431.1 858673 859758 D Escherichia coli K-12 ortholog: b0801; Escherichia coli O157:H7 ortholog: z1022; hypothetical protein 858673..859758 Escherichia coli CFT073 1037826 NP_752816.1 CDS ybiJ NC_004431.1 859986 860246 R Escherichia coli K-12 ortholog: b0802; Escherichia coli O157:H7 ortholog: z1023; hypothetical protein complement(859986..860246) Escherichia coli CFT073 1037831 YP_004853798.1 CDS c0887 NC_004431.1 860501 860866 R hypothetical protein complement(860501..860866) Escherichia coli CFT073 1039966 NP_752818.1 CDS c0888 NC_004431.1 860511 860777 R Escherichia coli K-12 ortholog: b0803; Escherichia coli O157:H7 ortholog: z1024; hypothetical protein complement(860511..860777) Escherichia coli CFT073 1035788 NP_752819.2 CDS ybiX NC_004431.1 860851 861528 R Escherichia coli K-12 ortholog: b0804; Escherichia coli O157:H7 ortholog: z1025; hydroxylase complement(860851..861528) Escherichia coli CFT073 1037849 NP_752820.1 CDS ybiL NC_004431.1 861744 864026 R Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu complement(861744..864026) Escherichia coli CFT073 1037863 NP_752821.1 CDS ybiM NC_004431.1 864291 864695 R Escherichia coli K-12 ortholog: b0806; Escherichia coli O157:H7 ortholog: z1027; hypothetical protein complement(864291..864695) Escherichia coli CFT073 1037841 NP_752822.1 CDS ybiN NC_004431.1 864737 865753 D Escherichia coli K-12 ortholog: b0807; Escherichia coli O157:H7 ortholog: z1028; SAM-dependent methyltransferase 864737..865753 Escherichia coli CFT073 1037684 NP_752823.2 CDS ybiO NC_004431.1 865750 867975 R Escherichia coli K-12 ortholog: b0808; Escherichia coli O157:H7 ortholog: z1030; hypothetical protein complement(865750..867975) Escherichia coli CFT073 1037837 NP_752824.1 CDS glnQ NC_004431.1 868092 868814 R similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein complement(868092..868814) Escherichia coli CFT073 1037899 NP_752825.1 CDS glnP NC_004431.1 868811 869470 R similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease complement(868811..869470) Escherichia coli CFT073 1037881 NP_752826.1 CDS glnH NC_004431.1 869609 870355 R similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein complement(869609..870355) Escherichia coli CFT073 1037866 NP_752827.1 CDS c0897 NC_004431.1 870282 870473 R hypothetical protein complement(870282..870473) Escherichia coli CFT073 1037880 NP_752828.2 CDS dps NC_004431.1 870759 871262 R binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps complement(870759..871262) Escherichia coli CFT073 1037923 NP_752829.1 CDS ybiF NC_004431.1 871563 872462 R Escherichia coli K-12 ortholog: b0813; Escherichia coli O157:H7 ortholog: z1035; threonine and homoserine efflux system complement(871563..872462) Escherichia coli CFT073 1039968 NP_752830.1 CDS ompX NC_004431.1 872797 873318 D OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 872797..873318 Escherichia coli CFT073 1037896 NP_752831.1 CDS ybiP NC_004431.1 873368 874951 R Escherichia coli K-12 ortholog: b0815; Escherichia coli O157:H7 ortholog: z1037; hypothetical protein complement(873368..874951) Escherichia coli CFT073 1037891 NP_752832.1 CDS c0902 NC_004431.1 875223 875351 R hypothetical protein complement(875223..875351) Escherichia coli CFT073 1037900 NP_752833.1 CDS c0903 NC_004431.1 875537 876004 D Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 875537..876004 Escherichia coli CFT073 1037887 NP_752834.1 CDS ybiR NC_004431.1 876001 877119 D Escherichia coli K-12 ortholog: b0818; Escherichia coli O157:H7 ortholog: z1040; hypothetical protein 876001..877119 Escherichia coli CFT073 1037938 NP_752835.1 CDS ybiS NC_004431.1 877177 878097 R Escherichia coli K-12 ortholog: b0819; Escherichia coli O157:H7 ortholog: z1041; hypothetical protein complement(877177..878097) Escherichia coli CFT073 1037947 NP_752836.1 CDS ybiT NC_004431.1 878316 879908 D Escherichia coli K-12 ortholog: b0820; Escherichia coli O157:H7 ortholog: z1042; ABC transporter ATP-binding protein 878316..879908 Escherichia coli CFT073 1037954 NP_752837.1 CDS ybiV NC_004431.1 880108 880923 R Escherichia coli K-12 ortholog: b0822; Escherichia coli O157:H7 ortholog: z1044; hypothetical protein complement(880108..880923) Escherichia coli CFT073 1039970 NP_752838.1 CDS ybiW NC_004431.1 881069 883501 R Escherichia coli K-12 ortholog: b0823; Escherichia coli O157:H7 ortholog: z1045; formate acetyltransferase 3 complement(881069..883501) Escherichia coli CFT073 1037922 NP_752839.1 CDS c0909 NC_004431.1 883507 884433 R Escherichia coli K-12 ortholog: b0824; Escherichia coli O157:H7 ortholog: z1047; pyruvate formate-lyase 3 activating enzyme complement(883507..884433) Escherichia coli CFT073 1037979 NP_752840.2 CDS mipB NC_004431.1 884537 885199 D similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 884537..885199 Escherichia coli CFT073 1037976 NP_752841.1 CDS moeB NC_004431.1 885275 886024 R ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB complement(885275..886024) Escherichia coli CFT073 1035793 NP_752842.1 CDS moeA NC_004431.1 886024 887259 R is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA complement(886024..887259) Escherichia coli CFT073 1038013 NP_752843.1 CDS ybiK NC_004431.1 887463 888428 D Escherichia coli K-12 ortholog: b0828; Escherichia coli O157:H7 ortholog: z1052; L-asparaginase 887463..888428 Escherichia coli CFT073 1035820 NP_752844.1 CDS yliA NC_004431.1 888397 890286 D with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 888397..890286 Escherichia coli CFT073 1037970 NP_752845.1 CDS c0915 NC_004431.1 890150 891844 D Escherichia coli K-12 ortholog: b0830; Escherichia coli O157:H7 ortholog: z1054; binding protein yliB 890150..891844 Escherichia coli CFT073 1037986 NP_752846.1 CDS yliC NC_004431.1 891862 892782 D Escherichia coli K-12 ortholog: b0831; Escherichia coli O157:H7 ortholog: z1055; ABC transporter permease 891862..892782 Escherichia coli CFT073 1037991 NP_752847.1 CDS yliD NC_004431.1 892785 893696 D Escherichia coli K-12 ortholog: b0832; Escherichia coli O157:H7 ortholog: z1056; ABC transporter permease 892785..893696 Escherichia coli CFT073 1037977 NP_752848.1 CDS yliE NC_004431.1 893873 896221 D Escherichia coli K-12 ortholog: b0833; Escherichia coli O157:H7 ortholog: z1057; hypothetical protein 893873..896221 Escherichia coli CFT073 1037993 NP_752849.1 CDS yliF NC_004431.1 896229 897557 D Escherichia coli K-12 ortholog: b0834; Escherichia coli O157:H7 ortholog: z1058; membrane protein yliF 896229..897557 Escherichia coli CFT073 1036723 NP_752850.1 CDS rimO NC_004431.1 897604 898929 R catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase complement(897604..898929) Escherichia coli CFT073 1037995 NP_752851.2 CDS bssR NC_004431.1 899142 899525 D BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 899142..899525 Escherichia coli CFT073 1038056 NP_752852.1 CDS yliI NC_004431.1 899636 900751 D Escherichia coli K-12 ortholog: b0837; Escherichia coli O157:H7 ortholog: z1063; hypothetical protein 899636..900751 Escherichia coli CFT073 1038001 NP_752853.1 CDS yliJ NC_004431.1 900748 901380 R Escherichia coli K-12 ortholog: b0838; Escherichia coli O157:H7 ortholog: z1064; GST-like protein yliJ complement(900748..901380) Escherichia coli CFT073 1038015 NP_752854.1 CDS dacC NC_004431.1 901600 902823 D penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase fraction C 901600..902823 Escherichia coli CFT073 1038062 NP_752855.1 CDS deoR NC_004431.1 902870 903628 R Escherichia coli K-12 ortholog: b0840; Escherichia coli O157:H7 ortholog: z1067; DNA-binding transcriptional repressor DeoR complement(902870..903628) Escherichia coli CFT073 1037990 NP_752856.1 CDS ybjG NC_004431.1 903686 904282 R Escherichia coli K-12 ortholog: b0841; Escherichia coli O157:H7 ortholog: z1068; undecaprenyl pyrophosphate phosphatase complement(903686..904282) Escherichia coli CFT073 1039972 NP_752857.1 CDS cmr NC_004431.1 904537 905799 D Chloramphenicol resistance pump cmr; Escherichia coli K-12 ortholog: b0842; Escherichia coli O157:H7 ortholog: z1069; multidrug translocase mdfA 904537..905799 Escherichia coli CFT073 1038021 NP_752858.1 CDS ybjH NC_004431.1 905840 906124 R Escherichia coli K-12 ortholog: b0843; Escherichia coli O157:H7 ortholog: z1070; hypothetical protein complement(905840..906124) Escherichia coli CFT073 1038074 NP_752859.1 CDS c0929 NC_004431.1 906210 907028 R Escherichia coli K-12 ortholog: b0844; Escherichia coli O157:H7 ortholog: z1071; hypothetical protein complement(906210..907028) Escherichia coli CFT073 1038014 NP_752860.1 CDS ybjJ NC_004431.1 907025 908296 R Escherichia coli K-12 ortholog: b0845; Escherichia coli O157:H7 ortholog: z1072; hypothetical protein complement(907025..908296) Escherichia coli CFT073 1036747 NP_752861.1 CDS ybjK NC_004431.1 908287 908853 D Escherichia coli K-12 ortholog: b0846; Escherichia coli O157:H7 ortholog: z1073; hypothetical protein 908287..908853 Escherichia coli CFT073 1038055 NP_752862.1 CDS intT NC_004431.1 909332 910363 R Escherichia coli O157:H7 ortholog: z2966; integrase for prophage complement(909332..910363) Escherichia coli CFT073 1038068 NP_752863.1 CDS c0933 NC_004431.1 910450 911421 R hypothetical protein complement(910450..911421) Escherichia coli CFT073 1035786 NP_752864.1 CDS c0934 NC_004431.1 911434 912360 R Residues 114 to 307 of 308 are 47.42 pct identical to residues 5 to 198 of 198 from SwissProt.40 : >sp|P21323|YR7I_ECOLI HYPOTHETICAL 21.9 KD PROTEIN (ORFI) (RETRON EC67); hypothetical protein complement(911434..912360) Escherichia coli CFT073 1038070 NP_752865.1 CDS coxT NC_004431.1 912449 912670 D Escherichia coli O157:H7 ortholog: z2970; regulator for prophage 912449..912670 Escherichia coli CFT073 1038063 NP_752866.1 CDS c0936 NC_004431.1 912649 913212 D Residues 19 to 187 of 187 are 99.40 pct identical to residues 1 to 169 of 169 from SwissProt.40 : >sp|P21316|YR7B_ECOLI HYPOTHETICAL 18.1 KD PROTEIN (ORFB) (RETRON EC67); hypothetical protein 912649..913212 Escherichia coli CFT073 1039982 NP_752867.1 CDS c0937 NC_004431.1 913190 913420 D Residues 11 to 60 of 76 are 81.99 pct identical to residues 1 to 50 of 75 from SwissProt.40 : >sp|P15236|VFIL_BP186 FIL PROTEIN; hypothetical protein 913190..913420 Escherichia coli CFT073 1038133 NP_752868.1 CDS c0938 NC_004431.1 913522 913725 D Residues 1 to 67 of 67 are 100.00 pct identical to residues 47 to 113 of 113 from GenPept.129 : >emb|CAD09425.1| (AL627279) conserved hypothetical protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein 913522..913725 Escherichia coli CFT073 1038096 NP_752869.1 CDS c0939 NC_004431.1 913787 914026 D Residues 9 to 79 of 79 are 46.47 pct identical to residues 7 to 77 of 77 from SwissProt.40 : >sp|P21682|CP79_BP186 Hypothetical 8.8 kDa protein in GPA 5'region; hypothetical protein 913787..914026 Escherichia coli CFT073 1038115 NP_752870.1 CDS c0940 NC_004431.1 914038 914253 D Escherichia coli K-12 ortholog: b0803; Escherichia coli O157:H7 ortholog: z1024; hypothetical protein 914038..914253 Escherichia coli CFT073 1038089 NP_752871.1 CDS c0941 NC_004431.1 914250 915107 D Escherichia coli K-12 ortholog: b3387; Escherichia coli O157:H7 ortholog: z4740; DNA adenine methylase 914250..915107 Escherichia coli CFT073 1038112 NP_752872.1 CDS c0942 NC_004431.1 915104 917518 D Escherichia coli O157:H7 ortholog: z2978; replication protein for prophage 915104..917518 Escherichia coli CFT073 1038292 NP_752873.1 CDS c0943 NC_004431.1 917799 918104 D Residues 25 to 101 of 101 are 98.70 pct identical to residues 1 to 77 of 77 from SwissProt.40 : >sp|P21320|DIIR_ECOLI DinI-like protein in Retron EC67; hypothetical protein 917799..918104 Escherichia coli CFT073 1038160 NP_752874.1 CDS c0944 NC_004431.1 918325 918525 D hypothetical protein 918325..918525 Escherichia coli CFT073 1038190 NP_752875.1 CDS c0945 NC_004431.1 918529 919311 D hypothetical protein 918529..919311 Escherichia coli CFT073 1038286 NP_752876.1 CDS c0946 NC_004431.1 919531 920685 D Residues 28 to 104 of 384 are 36.36 pct identical to residues 154 to 230 of 266 from GenPept.129 : >gb|AAB91582.2| (AF242881) ymh [Agrobacterium tumefaciens]; hypothetical protein 919531..920685 Escherichia coli CFT073 1035785 NP_752877.1 CDS c0947 NC_004431.1 920737 921774 R Residues 2 to 300 of 345 are 96.98 pct identical to residues 1 to 299 of 326 from SwissProt.40 : >sp|P21314|YR75_ECOLI HYPOTHETICAL 36.8 KD PROTEIN (ORF5) (RETRON EC67); capsid portal protein complement(920737..921774) Escherichia coli CFT073 1038303 NP_752878.1 CDS c0948 NC_004431.1 921771 923537 R Residues 3 to 588 of 588 are 63.38 pct identical to residues 4 to 590 of 590 from SwissProt.40 : >sp|P25479|VPP_BPP2 TERMINASE, ATPASE SUBUNIT (GPP); terminase, ATPase subunit complement(921771..923537) Escherichia coli CFT073 1036751 NP_752879.1 CDS c0949 NC_004431.1 923547 923708 R hypothetical protein complement(923547..923708) Escherichia coli CFT073 1035373 NP_752880.1 CDS c0950 NC_004431.1 923686 924513 D Residues 3 to 275 of 275 are 46.42 pct identical to residues 6 to 284 of 284 from SwissProt.40 : >sp|P25478|VPO_BPP2 PRESUMED CAPSID SCAFFOLDING PROTEIN (GPO); capsid scaffolding protein 923686..924513 Escherichia coli CFT073 1038287 NP_752881.1 CDS c0951 NC_004431.1 924410 925702 R hypothetical protein complement(924410..925702) Escherichia coli CFT073 1039978 NP_752882.1 CDS c0952 NC_004431.1 924530 925588 D Residues 1 to 352 of 352 are 58.82 pct identical to residues 1 to 357 of 357 from SwissProt.40 : >sp|P25477|VPN_BPP2 MAJOR CAPSID PROTEIN PRECURSOR (GPN); major capsid protein 924530..925588 Escherichia coli CFT073 1038309 NP_752883.1 CDS c0953 NC_004431.1 925691 926242 D Residues 1 to 179 of 183 are 49.72 pct identical to residues 34 to 214 of 247 from SwissProt.40 : >sp|P25476|VPM_BPP2 TERMINASE, ENDONUCLEASE SUBUNIT (GPM); terminase, endonuclease subunit 925691..926242 Escherichia coli CFT073 1038315 NP_752884.1 CDS c0954 NC_004431.1 926275 926802 D Residues 1 to 175 of 175 are 98.28 pct identical to residues 1 to 175 of 175 from GenPept.129 : >emb|CAD09440.1| (AL627279) capsid completion protein [Salmonella enterica subsp. enterica serovar Typhi]; capsid completion protein 926275..926802 Escherichia coli CFT073 1038218 NP_752885.1 CDS c0955 NC_004431.1 926802 927005 D Residues 1 to 67 of 67 are 61.19 pct identical to residues 1 to 67 of 67 from SwissProt.40 : >sp|P51772|VPX_BPP2 TAIL PROTEIN X (GPX); phage tail protein 926802..927005 Escherichia coli CFT073 1035784 NP_752886.1 CDS c0956 NC_004431.1 927009 927224 D Residues 1 to 71 of 71 are 98.59 pct identical to residues 1 to 71 of 71 from GenPept.129 : >emb|CAD09442.1| (AL627279) possible secretory protein [Salmonella enterica subsp. enterica serovar Typhi]; secretory protein 927009..927224 Escherichia coli CFT073 1038343 NP_752887.1 CDS c0957 NC_004431.1 927205 927717 D Residues 1 to 168 of 170 are 91.66 pct identical to residues 1 to 168 of 169 from GenPept.129 : >gb|AAL21602.1| (AE008823) Fels-2 prophage: probable prophage lysozyme [Salmonella typhimurium LT2]; Fels-2 prophage: prophage lysozyme 927205..927717 Escherichia coli CFT073 1038294 NP_752888.1 CDS c0958 NC_004431.1 927677 928096 D Residues 15 to 139 of 139 are 98.40 pct identical to residues 1 to 125 of 125 from GenPept.129 : >emb|CAD09444.1| (AL627279) membrane protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein 927677..928096 Escherichia coli CFT073 1038301 NP_752889.1 CDS c0959 NC_004431.1 928093 928521 D Residues 1 to 142 of 142 are 95.07 pct identical to residues 1 to 142 of 142 from GenPept.129 : >emb|CAD09445.1| (AL627279) regulatory protein [Salmonella enterica subsp. enterica serovar Typhi]; regulatory protein 928093..928521 Escherichia coli CFT073 1039980 NP_752890.1 CDS c0960 NC_004431.1 928596 929048 D Residues 10 to 142 of 150 are 50.37 pct identical to residues 3 to 135 of 155 from SwissProt.40 : >sp|P36933|VPR_BPP2 TAIL COMPLETION PROTEIN R (GPR); phage tail protein 928596..929048 Escherichia coli CFT073 1038328 NP_752891.1 CDS c0961 NC_004431.1 928963 929520 R hypothetical protein complement(928963..929520) Escherichia coli CFT073 1038330 NP_752892.1 CDS c0962 NC_004431.1 929041 929487 D Residues 1 to 148 of 148 are 98.64 pct identical to residues 1 to 148 of 148 from GenPept.129 : >emb|CAD09447.1| (AL627279) phage tail protein [Salmonella enterica subsp. enterica serovar Typhi]; phage tail protein 929041..929487 Escherichia coli CFT073 1038342 NP_752893.1 CDS c0963 NC_004431.1 929556 930134 D Residues 3 to 192 of 192 are 40.19 pct identical to residues 5 to 211 of 211 from SwissProt.40 : >sp|P31340|VPV_BPP2 BASEPLATE ASSEMBLY PROTEIN V (GPV); Phage baseplate assembly protein 929556..930134 Escherichia coli CFT073 1038354 NP_752894.1 CDS c0964 NC_004431.1 930131 930490 D Residues 4 to 110 of 119 are 53.70 pct identical to residues 5 to 112 of 115 from SwissProt.40 : >sp|P51768|VPW_BPP2 BASEPLATE ASSEMBLY PROTEIN W (GPW); Phage baseplate assembly protein 930131..930490 Escherichia coli CFT073 1038367 NP_752895.1 CDS c0965 NC_004431.1 930477 931385 D Residues 1 to 302 of 302 are 65.89 pct identical to residues 1 to 302 of 302 from SwissProt.40 : >sp|P51767|VPJ_BPP2 BASEPLATE ASSEMBLY PROTEIN J (GPJ); Phage baseplate assembly protein 930477..931385 Escherichia coli CFT073 1038360 NP_752896.1 CDS c0966 NC_004431.1 931378 931983 D Residues 4 to 173 of 201 are 57.05 pct identical to residues 6 to 175 of 176 from SwissProt.40 : >sp|P26701|VPI_BPP2 TAIL PROTEIN I (GPI); phage tail protein 931378..931983 Escherichia coli CFT073 1038356 NP_752897.1 CDS c0967 NC_004431.1 931408 931989 R hypothetical protein complement(931408..931989) Escherichia coli CFT073 1036757 NP_752898.1 CDS c0968 NC_004431.1 931980 933419 D Residues 1 to 353 of 479 are 96.03 pct identical to residues 1 to 353 of 504 from GenPept.129 : >emb|CAD09452.1| (AL627279) probable variable tail fibre protein [Salmonella enterica subsp. enterica serovar Typhi]; variable tail fiber protein 931980..933419 Escherichia coli CFT073 1038355 NP_752899.1 CDS yfdK NC_004431.1 933422 933898 D Escherichia coli K-12 ortholog: b2354; hypothetical protein 933422..933898 Escherichia coli CFT073 1038348 NP_752900.1 CDS c0970 NC_004431.1 933882 934913 R Residues 2 to 297 of 343 are 26.87 pct identical to residues 5 to 301 of 401 from GenPept.129 : >emb|CAC07472.1| (AX009415) product = eps11 [Lactobacillus helveticus]; hypothetical protein complement(933882..934913) Escherichia coli CFT073 1038402 NP_752901.1 CDS c0971 NC_004431.1 935127 936299 D Escherichia coli O157:H7 ortholog: z2991; major tail sheath protein 935127..936299 Escherichia coli CFT073 1038398 NP_752902.1 CDS c0972 NC_004431.1 936309 936824 D Escherichia coli O157:H7 ortholog: z2990; tail fiber component of prophage 936309..936824 Escherichia coli CFT073 1038390 NP_752903.1 CDS c0973 NC_004431.1 936327 936911 R hypothetical protein complement(936327..936911) Escherichia coli CFT073 1038427 NP_752904.1 CDS c0974 NC_004431.1 936879 937181 D Residues 1 to 100 of 100 are 99.00 pct identical to residues 1 to 100 of 100 from GenPept.129 : >emb|CAD09459.1| (AL627279) phage tail protein [Salmonella enterica subsp. enterica serovar Typhi]; phage tail protein 936879..937181 Escherichia coli CFT073 1038413 NP_752905.1 CDS c0975 NC_004431.1 936908 937363 R hypothetical protein complement(936908..937363) Escherichia coli CFT073 1038374 NP_752906.1 CDS c0976 NC_004431.1 937542 940385 D Residues 1 to 947 of 947 are 97.67 pct identical to residues 79 to 1025 of 1025 from GenPept.129 : >emb|CAD09461.1| (AL627279) hypothetical protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein 937542..940385 Escherichia coli CFT073 1038411 NP_752907.1 CDS c0977 NC_004431.1 940382 940867 D Escherichia coli O157:H7 ortholog: z2985; tail fiber protein of prophage 940382..940867 Escherichia coli CFT073 1038394 NP_752908.1 CDS c0978 NC_004431.1 940864 941964 D Residues 15 to 364 of 366 are 56.52 pct identical to residues 15 to 381 of 389 from SwissProt.40 : >sp|P21679|VPD_BP186 LATE CONTROL GENE D PROTEIN (GPD); regulator of late gene expression 940864..941964 Escherichia coli CFT073 1035781 NP_752909.1 CDS ogrK NC_004431.1 942022 942273 D Escherichia coli K-12 ortholog: b2082; prophage P2 Ogr protein 942022..942273 Escherichia coli CFT073 1038434 NP_752910.1 CDS ybjL NC_004431.1 942509 944194 R Escherichia coli K-12 ortholog: b0847; Escherichia coli O157:H7 ortholog: z1074; hypothetical protein complement(942509..944194) Escherichia coli CFT073 1035782 NP_752911.1 CDS ybjM NC_004431.1 944464 944841 D Escherichia coli K-12 ortholog: b0848; Escherichia coli O157:H7 ortholog: z1075; hypothetical protein 944464..944841 Escherichia coli CFT073 1038432 NP_752912.2 CDS grxA NC_004431.1 944871 945128 R functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 1 complement(944871..945128) Escherichia coli CFT073 1038384 NP_752913.1 CDS ybjC NC_004431.1 945288 945575 D YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 945288..945575 Escherichia coli CFT073 1038452 NP_752914.1 CDS mdaA NC_004431.1 945559 946281 D NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 945559..946281 Escherichia coli CFT073 1038385 NP_752915.1 CDS rimK NC_004431.1 946342 947244 D responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 946342..947244 Escherichia coli CFT073 1035783 NP_752916.1 CDS ybjN NC_004431.1 947284 947808 D Escherichia coli K-12 ortholog: b0853; Escherichia coli O157:H7 ortholog: z1080; hypothetical protein 947284..947808 Escherichia coli CFT073 1038391 NP_752917.1 CDS potF NC_004431.1 948013 949269 D Escherichia coli K-12 ortholog: b0854; Escherichia coli O157:H7 ortholog: z1081; putrescine transporter subunit: periplasmic-binding component of ABC superfamily 948013..949269 Escherichia coli CFT073 1038465 NP_752918.2 CDS potG NC_004431.1 949364 950497 D part of the PotFGHI ATP-dependent putrescine transporter; putrescine transporter ATP-binding subunit 949364..950497 Escherichia coli CFT073 1038426 NP_752919.1 CDS potH NC_004431.1 950507 951451 D Escherichia coli K-12 ortholog: b0856; Escherichia coli O157:H7 ortholog: z1083; putrescine transporter subunit: membrane component of ABC superfamily 950507..951451 Escherichia coli CFT073 1038425 NP_752920.1 CDS potI NC_004431.1 951406 952293 D Escherichia coli K-12 ortholog: b0857; Escherichia coli O157:H7 ortholog: z1084; putrescine transporter subunit: membrane component of ABC superfamily 951406..952293 Escherichia coli CFT073 1040158 NP_752921.1 CDS ybjO NC_004431.1 952353 952841 D Escherichia coli K-12 ortholog: b0858; Escherichia coli O157:H7 ortholog: z1085; hypothetical protein 952353..952841 Escherichia coli CFT073 1035780 NP_752922.1 CDS rumB NC_004431.1 952882 954009 D RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 952882..954009 Escherichia coli CFT073 1036761 NP_752923.1 CDS artJ NC_004431.1 954038 954820 R Escherichia coli K-12 ortholog: b0860; Escherichia coli O157:H7 ortholog: z1090; arginine-binding periplasmic protein 2 complement(954038..954820) Escherichia coli CFT073 1038468 NP_752924.1 CDS artM NC_004431.1 954995 955663 R with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM complement(954995..955663) Escherichia coli CFT073 1038458 NP_752925.1 CDS artQ NC_004431.1 955663 956379 R with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ complement(955663..956379) Escherichia coli CFT073 1038501 NP_752926.1 CDS artI NC_004431.1 956386 957117 R Escherichia coli K-12 ortholog: b0863; Escherichia coli O157:H7 ortholog: z1093; arginine-binding periplasmic protein 1 complement(956386..957117) Escherichia coli CFT073 1038479 NP_752927.2 CDS artP NC_004431.1 957135 957863 R With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit complement(957135..957863) Escherichia coli CFT073 1038444 NP_752928.1 CDS ybjP NC_004431.1 958081 958620 R induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; lipoprotein complement(958081..958620) Escherichia coli CFT073 1035653 NP_752929.1 CDS ybjQ NC_004431.1 958722 959045 D Escherichia coli K-12 ortholog: b0866; Escherichia coli O157:H7 ortholog: z1099; hypothetical protein 958722..959045 Escherichia coli CFT073 1038521 NP_752930.1 CDS ybjR NC_004431.1 959042 959872 D Escherichia coli K-12 ortholog: b0867; Escherichia coli O157:H7 ortholog: z1100; N-acetylmuramoyl-L-alanine amidase 959042..959872 Escherichia coli CFT073 1038522 NP_752931.1 CDS c1001 NC_004431.1 959869 960945 R Escherichia coli K-12 ortholog: b0868; Escherichia coli O157:H7 ortholog: z1102; hypothetical protein complement(959869..960945) Escherichia coli CFT073 1036763 NP_752932.1 CDS ybjT NC_004431.1 960981 962486 R Escherichia coli K-12 ortholog: b0869; Escherichia coli O157:H7 ortholog: z1103; hypothetical protein complement(960981..962486) Escherichia coli CFT073 1038497 NP_752933.1 CDS ybjU NC_004431.1 962422 963423 R low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase complement(962422..963423) Escherichia coli CFT073 1038542 NP_752934.1 CDS poxB NC_004431.1 963460 965178 R catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase complement(963460..965178) Escherichia coli CFT073 1038558 NP_752935.1 CDS c1005 NC_004431.1 965311 966285 R Escherichia coli K-12 ortholog: b0872; Escherichia coli O157:H7 ortholog: z1106; HCP oxidoreductase, NADH-dependent complement(965311..966285) Escherichia coli CFT073 1036765 NP_752936.2 CDS ybjW NC_004431.1 966291 967943 R catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase complement(966291..967943) Escherichia coli CFT073 1038506 NP_752937.1 CDS ybjE NC_004431.1 968087 968986 R Escherichia coli K-12 ortholog: b0874; Escherichia coli O157:H7 ortholog: z1108; hypothetical protein complement(968087..968986) Escherichia coli CFT073 1038535 NP_752938.1 CDS c1008 NC_004431.1 968964 969098 D hypothetical protein 968964..969098 Escherichia coli CFT073 1038546 NP_752939.1 CDS aqpZ NC_004431.1 969480 970181 R porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z complement(969480..970181) Escherichia coli CFT073 1038573 NP_752940.1 CDS c1010 NC_004431.1 970388 970543 R hypothetical protein complement(970388..970543) Escherichia coli CFT073 1035779 NP_752941.1 CDS ybjD NC_004431.1 970601 972259 D Escherichia coli K-12 ortholog: b0876; Escherichia coli O157:H7 ortholog: z1110; hypothetical protein 970601..972259 Escherichia coli CFT073 1036768 NP_752942.1 CDS ybjX NC_004431.1 972256 973248 R Escherichia coli K-12 ortholog: b0877; Escherichia coli O157:H7 ortholog: z1112; hypothetical protein complement(972256..973248) Escherichia coli CFT073 1035773 NP_752943.1 CDS c1013 NC_004431.1 973317 973451 D Residues 1 to 44 of 44 are 93.18 pct identical to residues 1 to 44 of 44 from GenPept.129 : >dbj|BAA35596.1| (D90725) ORF_ID:o213#2 [Escherichia coli]; hypothetical protein 973317..973451 Escherichia coli CFT073 1038528 NP_752944.2 CDS macA NC_004431.1 973363 974478 D confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 973363..974478 Escherichia coli CFT073 1038502 NP_752945.1 CDS c1016 NC_004431.1 976078 976422 D Residues 1 to 114 of 114 are 99.12 pct identical to residues 535 to 648 of 648 from GenPept.129 : >gb|AAG55261.1|AE005269_5 (AE005269) ATP-binding component of a transport system [Escherichia coli O157:H7 EDL933]; hypothetical protein 976078..976422 Escherichia coli CFT073 1038537 NP_752946.1 CDS cspD NC_004431.1 976495 976749 R inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible; stationary phase/starvation inducible regulatory protein CspD complement(976495..976749) Escherichia coli CFT073 1035774 NP_752947.1 CDS clpS NC_004431.1 977042 977362 D involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 977042..977362 Escherichia coli CFT073 1038534 NP_752948.2 CDS clpA NC_004431.1 977393 979669 D ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 977393..979669 Escherichia coli CFT073 1038589 YP_004853799.1 CDS c1020 NC_004431.1 979726 980118 R hypothetical protein complement(979726..980118) Escherichia coli CFT073 1038552 NP_752950.1 CDS infA NC_004431.1 980354 980572 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(980354..980572) Escherichia coli CFT073 1035770 NP_752951.1 CDS aat NC_004431.1 980857 981561 R leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase complement(980857..981561) Escherichia coli CFT073 1038609 NP_752952.1 CDS cydC NC_004431.1 981603 983324 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding component complement(981603..983324) Escherichia coli CFT073 1038571 NP_752953.1 CDS cydD NC_004431.1 983325 985091 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding component complement(983325..985091) Escherichia coli CFT073 1038606 NP_752954.1 CDS trxB NC_004431.1 985214 986299 R catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase complement(985214..986299) Escherichia coli CFT073 1038595 NP_752955.2 CDS lrp NC_004431.1 986723 987217 D mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 986723..987217 Escherichia coli CFT073 1038629 NP_752956.1 CDS ftsK NC_004431.1 987352 991395 D DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 987352..991395 Escherichia coli CFT073 1038631 NP_752957.1 CDS lolA NC_004431.1 991551 992165 D participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 991551..992165 Escherichia coli CFT073 1039991 NP_752958.1 CDS ycaJ NC_004431.1 992176 993519 D Escherichia coli K-12 ortholog: b0892; Escherichia coli O157:H7 ortholog: z1238; recombination factor protein RarA 992176..993519 Escherichia coli CFT073 1038658 NP_752959.1 CDS serS NC_004431.1 993610 994902 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 993610..994902 Escherichia coli CFT073 1036773 NP_752960.1 CDS dmsA NC_004431.1 995141 997585 D Escherichia coli K-12 ortholog: b0894; Escherichia coli O157:H7 ortholog: z1240; anaerobic dimethyl sulfoxide reductase chain A 995141..997585 Escherichia coli CFT073 1038617 NP_752961.1 CDS dmsB NC_004431.1 997596 998213 D DMSO reductase iron-sulfur subunit; Escherichia coli K-12 ortholog: b0895; Escherichia coli O157:H7 ortholog: z1241; anaerobic dimethyl sulfoxide reductase chain B 997596..998213 Escherichia coli CFT073 1038639 NP_752962.1 CDS dmsC NC_004431.1 998215 999078 D DMSO reductase anchor subunit; Escherichia coli K-12 ortholog: b0896; Escherichia coli O157:H7 ortholog: z1242; anaerobic dimethyl sulfoxide reductase chain C 998215..999078 Escherichia coli CFT073 1038623 NP_752963.1 CDS ycaC NC_004431.1 999114 999839 R Escherichia coli K-12 ortholog: b0897; Escherichia coli O157:H7 ortholog: z1243; hypothetical protein complement(999114..999839) Escherichia coli CFT073 1036774 NP_752964.1 CDS c1035 NC_004431.1 999895 1000023 R hypothetical protein complement(999895..1000023) Escherichia coli CFT073 1038651 NP_752965.1 CDS c1036 NC_004431.1 999971 1000108 D hypothetical protein 999971..1000108 Escherichia coli CFT073 1038648 NP_752966.1 CDS ycaD NC_004431.1 1000054 1001202 D ORF Y; Escherichia coli K-12 ortholog: b0898; Escherichia coli O157:H7 ortholog: z1244; MFS family transporter protein 1000054..1001202 Escherichia coli CFT073 1038692 NP_752967.2 CDS pflA NC_004431.1 1001299 1002039 R activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 complement(1001299..1002039) Escherichia coli CFT073 1038676 NP_752968.1 CDS c1040 NC_004431.1 1003279 1004493 D hypothetical protein 1003279..1004493 Escherichia coli CFT073 1038678 NP_752969.1 CDS focA_2 NC_004431.1 1004569 1005765 R Formate channel 1; Escherichia coli K-12 ortholog: b0904; Escherichia coli O157:H7 ortholog: z1250; formate transporter complement(1004569..1005765) Escherichia coli CFT073 1038659 NP_752970.1 CDS ycaO NC_004431.1 1005832 1007625 R Escherichia coli K-12 ortholog: b0905; Escherichia coli O157:H7 ortholog: z1251; hypothetical protein complement(1005832..1007625) Escherichia coli CFT073 1036777 NP_752971.1 CDS ycaP NC_004431.1 1007722 1008414 D Escherichia coli K-12 ortholog: b0906; Escherichia coli O157:H7 ortholog: z1252; hypothetical protein 1007722..1008414 Escherichia coli CFT073 1035768 NP_752972.1 CDS serC NC_004431.1 1008613 1009701 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1008613..1009701 Escherichia coli CFT073 1039994 NP_752973.1 CDS aroA NC_004431.1 1009772 1011055 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1009772..1011055 Escherichia coli CFT073 1035769 NP_752974.1 CDS ycaL NC_004431.1 1011216 1011989 D Escherichia coli K-12 ortholog: b0909; Escherichia coli O157:H7 ortholog: z1255; metalloprotease ycaL 1011216..1011989 Escherichia coli CFT073 1038735 NP_752975.1 CDS cmk NC_004431.1 1012162 1012845 D Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1012162..1012845 Escherichia coli CFT073 1038671 NP_752976.1 CDS rpsA NC_004431.1 1012956 1014629 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1012956..1014629 Escherichia coli CFT073 1038789 NP_752977.1 CDS ihfB NC_004431.1 1014789 1015073 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1014789..1015073 Escherichia coli CFT073 1038705 NP_752978.1 CDS c1051 NC_004431.1 1014798 1015106 R hypothetical protein complement(1014798..1015106) Escherichia coli CFT073 1038020 NP_752979.2 CDS ycaI NC_004431.1 1015279 1017543 D Escherichia coli K-12 ortholog: b0913; Escherichia coli O157:H7 ortholog: z1259; hypothetical protein 1015279..1017543 Escherichia coli CFT073 1038691 YP_004853800.1 CDS c1053 NC_004431.1 1016634 1016768 D hypothetical protein 1016634..1016768 Escherichia coli CFT073 1038772 NP_752981.1 CDS msbA NC_004431.1 1017580 1019328 D involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease 1017580..1019328 Escherichia coli CFT073 1038715 NP_752982.1 CDS ycaQ NC_004431.1 1020349 1021581 D Escherichia coli K-12 ortholog: b0916; Escherichia coli O157:H7 ortholog: z1262; hypothetical protein 1020349..1021581 Escherichia coli CFT073 1036780 NP_752983.1 CDS ycaR NC_004431.1 1021633 1021815 D Escherichia coli K-12 ortholog: b0917; Escherichia coli O157:H7 ortholog: z1263; hypothetical protein 1021633..1021815 Escherichia coli CFT073 1038719 NP_752984.1 CDS kdsB NC_004431.1 1021812 1022558 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 1021812..1022558 Escherichia coli CFT073 1038778 NP_752985.1 CDS ycbJ NC_004431.1 1022712 1023605 D Escherichia coli K-12 ortholog: b0919; Escherichia coli O157:H7 ortholog: z1265; hypothetical protein 1022712..1023605 Escherichia coli CFT073 1038766 NP_752986.1 CDS ycbC NC_004431.1 1023582 1024361 R Escherichia coli K-12 ortholog: b0920; Escherichia coli O157:H7 ortholog: z1267; hypothetical protein complement(1023582..1024361) Escherichia coli CFT073 1038770 NP_752987.1 CDS c1062 NC_004431.1 1024264 1024428 R hypothetical protein complement(1024264..1024428) Escherichia coli CFT073 1038818 NP_752988.1 CDS smtA NC_004431.1 1024485 1025282 D involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; metallothionein SmtA 1024485..1025282 Escherichia coli CFT073 1038811 NP_752989.1 CDS mukF NC_004431.1 1025279 1026601 D acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 1025279..1026601 Escherichia coli CFT073 1038835 NP_752990.1 CDS mukE NC_004431.1 1026555 1027286 D acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 1026555..1027286 Escherichia coli CFT073 1038800 NP_752991.1 CDS mukB NC_004431.1 1027286 1031746 D SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 1027286..1031746 Escherichia coli CFT073 1038807 NP_752992.1 CDS ycbB NC_004431.1 1032007 1033854 D Escherichia coli K-12 ortholog: b0925; Escherichia coli O157:H7 ortholog: z1272; hypothetical protein 1032007..1033854 Escherichia coli CFT073 1038825 NP_752993.1 CDS ycbK NC_004431.1 1034026 1034583 D Escherichia coli K-12 ortholog: b0926; Escherichia coli O157:H7 ortholog: z1273; hypothetical protein 1034026..1034583 Escherichia coli CFT073 1038827 NP_752994.1 CDS ycbL NC_004431.1 1034610 1035257 D Escherichia coli K-12 ortholog: b0927; Escherichia coli O157:H7 ortholog: z1274; hypothetical protein 1034610..1035257 Escherichia coli CFT073 1038823 NP_752995.1 CDS aspC NC_004431.1 1035307 1036497 R catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase complement(1035307..1036497) Escherichia coli CFT073 1038848 NP_752996.1 CDS ompF NC_004431.1 1036682 1037770 R outer membrane porin F; 1a; Ia; b; outer membrane protein F complement(1036682..1037770) Escherichia coli CFT073 1038831 NP_752997.1 CDS asnC NC_004431.1 1038373 1039773 R catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase complement(1038373..1039773) Escherichia coli CFT073 1036783 NP_752998.1 CDS pncB NC_004431.1 1039942 1041192 R catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(1039942..1041192) Escherichia coli CFT073 1038812 NP_752999.1 CDS c1074 NC_004431.1 1039960 1040145 D hypothetical protein 1039960..1040145 Escherichia coli CFT073 1038840 NP_753000.1 CDS pepN NC_004431.1 1041410 1044022 D Escherichia coli K-12 ortholog: b0932; Escherichia coli O157:H7 ortholog: z1280; aminopeptidase 1041410..1044022 Escherichia coli CFT073 1035766 NP_753001.1 CDS ssuB NC_004431.1 1044217 1044984 R part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit complement(1044217..1044984) Escherichia coli CFT073 1038887 NP_753002.1 CDS ssuC NC_004431.1 1044981 1045775 R part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease subunit complement(1044981..1045775) Escherichia coli CFT073 1035762 NP_753003.1 CDS ycbN NC_004431.1 1045784 1046929 R catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase complement(1045784..1046929) Escherichia coli CFT073 1038862 NP_753004.2 CDS ycbO NC_004431.1 1046926 1047885 R part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit complement(1046926..1047885) Escherichia coli CFT073 1038819 NP_753005.1 CDS ycbP NC_004431.1 1047878 1048453 R Escherichia coli K-12 ortholog: b0937; Escherichia coli O157:H7 ortholog: z1285; NAD(P)H-dependent FMN reductase complement(1047878..1048453) Escherichia coli CFT073 1038901 NP_753006.1 CDS pyrD NC_004431.1 1048663 1049700 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1048663..1049700 Escherichia coli CFT073 1039998 NP_753007.1 CDS ycbW NC_004431.1 1049838 1050416 D Escherichia coli K-12 ortholog: b0946; Escherichia coli O157:H7 ortholog: z1295; hypothetical protein 1049838..1050416 Escherichia coli CFT073 1035764 NP_753008.1 CDS ycbX NC_004431.1 1050413 1051522 R Escherichia coli K-12 ortholog: b0947; Escherichia coli O157:H7 ortholog: z1297; hypothetical protein complement(1050413..1051522) Escherichia coli CFT073 1038837 NP_753009.1 CDS rlmL NC_004431.1 1051620 1053728 D catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1051620..1053728 Escherichia coli CFT073 1038883 NP_753010.1 CDS uup NC_004431.1 1053740 1055647 D Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase component 1053740..1055647 Escherichia coli CFT073 1038871 NP_753011.1 CDS pqiA NC_004431.1 1055777 1057030 D Escherichia coli K-12 ortholog: b0950; Escherichia coli O157:H7 ortholog: z1300; paraquat-inducible protein A 1055777..1057030 Escherichia coli CFT073 1035761 NP_753012.1 CDS pqiB NC_004431.1 1056975 1058675 D Escherichia coli K-12 ortholog: b0951; Escherichia coli O157:H7 ortholog: z1301; paraquat-inducible protein B 1056975..1058675 Escherichia coli CFT073 1038905 NP_753013.1 CDS ymbA NC_004431.1 1058672 1059235 D Escherichia coli K-12 ortholog: b0952; Escherichia coli O157:H7 ortholog: z1302; hypothetical protein 1058672..1059235 Escherichia coli CFT073 1038912 NP_753014.1 CDS c1089 NC_004431.1 1059400 1059531 R hypothetical protein complement(1059400..1059531) Escherichia coli CFT073 1038894 NP_753015.2 CDS fabA NC_004431.1 1059727 1060245 R catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase complement(1059727..1060245) Escherichia coli CFT073 1038890 NP_753016.1 CDS c1091 NC_004431.1 1060314 1062074 R Escherichia coli K-12 ortholog: b0955; Escherichia coli O157:H7 ortholog: z1305; protease La-like protein complement(1060314..1062074) Escherichia coli CFT073 1038931 NP_753017.1 CDS ycbG NC_004431.1 1062260 1062712 D Escherichia coli K-12 ortholog: b0956; Escherichia coli O157:H7 ortholog: z1306; hypothetical protein 1062260..1062712 Escherichia coli CFT073 1038947 NP_753018.1 CDS ompA NC_004431.1 1062790 1063929 R OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A complement(1062790..1063929) Escherichia coli CFT073 1039999 NP_753019.1 CDS c1094 NC_004431.1 1063996 1064214 D hypothetical protein 1063996..1064214 Escherichia coli CFT073 1036798 NP_753020.1 CDS sulA NC_004431.1 1064198 1064713 R Escherichia coli K-12 ortholog: b0958; Escherichia coli O157:H7 ortholog: z1308; SOS cell division inhibitor complement(1064198..1064713) Escherichia coli CFT073 1038951 NP_753021.1 CDS yccR NC_004431.1 1064926 1065555 D Escherichia coli K-12 ortholog: b0959; Escherichia coli O157:H7 ortholog: z1309; hypothetical protein 1064926..1065555 Escherichia coli CFT073 1038964 NP_753022.1 CDS yccS NC_004431.1 1065518 1067680 R Escherichia coli K-12 ortholog: b0960; Escherichia coli O157:H7 ortholog: z1311; hypothetical protein complement(1065518..1067680) Escherichia coli CFT073 1038952 NP_753023.1 CDS yccF NC_004431.1 1067690 1068136 R Escherichia coli K-12 ortholog: b0961; Escherichia coli O157:H7 ortholog: z1312; hypothetical protein complement(1067690..1068136) Escherichia coli CFT073 1038934 NP_753024.2 CDS helD NC_004431.1 1068259 1070313 D catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1068259..1070313 Escherichia coli CFT073 1038988 NP_753025.2 CDS mgsA NC_004431.1 1070345 1070803 R catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase complement(1070345..1070803) Escherichia coli CFT073 1038977 NP_753026.1 CDS yccT NC_004431.1 1070899 1071561 R Escherichia coli K-12 ortholog: b0964; Escherichia coli O157:H7 ortholog: z1315; hypothetical protein complement(1070899..1071561) Escherichia coli CFT073 1038991 NP_753027.1 CDS c1102 NC_004431.1 1071653 1072147 D Escherichia coli K-12 ortholog: b0965; Escherichia coli O157:H7 ortholog: z1317; hypothetical protein 1071653..1072147 Escherichia coli CFT073 1038965 NP_753028.1 CDS c1103 NC_004431.1 1072116 1072511 D hypothetical protein 1072116..1072511 Escherichia coli CFT073 1035759 NP_753029.1 CDS yccV NC_004431.1 1072192 1072560 R Escherichia coli K-12 ortholog: b0966; Escherichia coli O157:H7 ortholog: z1318; heat shock protein HspQ complement(1072192..1072560) Escherichia coli CFT073 1039016 NP_753030.1 CDS yccW NC_004431.1 1072567 1073757 R Escherichia coli K-12 ortholog: b0967; Escherichia coli O157:H7 ortholog: z1319; hypothetical protein complement(1072567..1073757) Escherichia coli CFT073 1035760 NP_753031.1 CDS c1106 NC_004431.1 1073732 1074130 D catalyzes the hydrolysis of acylphosphate; acylphosphatase 1073732..1074130 Escherichia coli CFT073 1039010 NP_753032.1 CDS yccK NC_004431.1 1074127 1074456 R transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE complement(1074127..1074456) Escherichia coli CFT073 1038946 YP_004853801.1 CDS c1108 NC_004431.1 1074172 1074474 D hypothetical protein 1074172..1074474 Escherichia coli CFT073 1039031 YP_004853802.1 CDS c1109 NC_004431.1 1074542 1075186 D hypothetical protein 1074542..1075186 Escherichia coli CFT073 1038980 NP_753035.1 CDS yccA NC_004431.1 1074548 1075207 R Escherichia coli K-12 ortholog: b0970; Escherichia coli O157:H7 ortholog: z1322; hypothetical protein complement(1074548..1075207) Escherichia coli CFT073 1035757 YP_004853803.1 CDS c1111 NC_004431.1 1075409 1075585 R hypothetical protein complement(1075409..1075585) Escherichia coli CFT073 1039007 NP_753037.1 CDS c1112 NC_004431.1 1075769 1075909 R hypothetical protein complement(1075769..1075909) Escherichia coli CFT073 1038996 NP_753038.1 CDS hyaA NC_004431.1 1075901 1077046 D Escherichia coli K-12 ortholog: b0972; Escherichia coli O157:H7 ortholog: z1389; hydrogenase-1 small chain 1075901..1077046 Escherichia coli CFT073 1040006 NP_753039.1 CDS hyaB NC_004431.1 1077043 1078836 D involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 1077043..1078836 Escherichia coli CFT073 1035758 NP_753040.1 CDS hyaC NC_004431.1 1078855 1079562 D Escherichia coli K-12 ortholog: b0974; Escherichia coli O157:H7 ortholog: z1391; hydrogenase 1 b-type cytochrome subunit 1078855..1079562 Escherichia coli CFT073 1036808 NP_753041.1 CDS hyaD NC_004431.1 1079559 1080146 D HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 1079559..1080146 Escherichia coli CFT073 1039024 NP_753042.1 CDS hyaE NC_004431.1 1080143 1080541 D involved in processing hydrogenase proteins HyaA and HyaB; hydrogenase-1 operon protein HyaE 1080143..1080541 Escherichia coli CFT073 1039028 NP_753043.1 CDS hyaF NC_004431.1 1080538 1081395 D Escherichia coli K-12 ortholog: b0977; Escherichia coli O157:H7 ortholog: z1394; hydrogenase-1 operon protein HyaF 1080538..1081395 Escherichia coli CFT073 1039059 NP_753044.1 CDS appC NC_004431.1 1081529 1083073 D Escherichia coli K-12 ortholog: b0978; Escherichia coli O157:H7 ortholog: z1395; cytochrome bd-II oxidase subunit I 1081529..1083073 Escherichia coli CFT073 1039033 NP_753045.1 CDS appB NC_004431.1 1083085 1084221 D Escherichia coli K-12 ortholog: b0979; Escherichia coli O157:H7 ortholog: z1396; cytochrome bd-II oxidase subunit II 1083085..1084221 Escherichia coli CFT073 1039056 NP_753046.1 CDS appA NC_004431.1 1084376 1085716 D Escherichia coli K-12 ortholog: b0980; Escherichia coli O157:H7 ortholog: z1397; bifunctional; phosphoanhydride phosphorylase 1084376..1085716 Escherichia coli CFT073 1039047 NP_753047.1 CDS cspH NC_004431.1 1085704 1085916 R CSP-H; Escherichia coli K-12 ortholog: b0989; Escherichia coli O157:H7 ortholog: z1405; cold shock-like protein cspH complement(1085704..1085916) Escherichia coli CFT073 1039038 NP_753048.1 CDS cspG NC_004431.1 1086202 1086414 D CSP-G; Escherichia coli K-12 ortholog: b0990; Escherichia coli O157:H7 ortholog: z1406; cold shock protein CspG 1086202..1086414 Escherichia coli CFT073 1039086 NP_753049.1 CDS sfa NC_004431.1 1086555 1086818 D Escherichia coli K-12 ortholog: b0991; Escherichia coli O157:H7 ortholog: z1408; cold shock gene 1086555..1086818 Escherichia coli CFT073 1039036 NP_753050.1 CDS c1125 NC_004431.1 1086808 1086981 D Escherichia coli K-12 ortholog: b1550; GnsB protein 1086808..1086981 Escherichia coli CFT073 1040007 NP_753051.1 CDS c1126 NC_004431.1 1086823 1086996 R hypothetical protein complement(1086823..1086996) Escherichia coli CFT073 1039123 NP_753052.1 CDS yccM NC_004431.1 1087030 1088103 R Escherichia coli K-12 ortholog: b0992; Escherichia coli O157:H7 ortholog: z1409; electron transport protein yccM complement(1087030..1088103) Escherichia coli CFT073 1036811 NP_753053.2 CDS torS NC_004431.1 1088186 1090918 R Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS complement(1088186..1090918) Escherichia coli CFT073 1039114 YP_004853804.1 CDS c1129 NC_004431.1 1090698 1090967 R hypothetical protein complement(1090698..1090967) Escherichia coli CFT073 1039065 NP_753055.1 CDS torT NC_004431.1 1091001 1092029 D periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 1091001..1092029 Escherichia coli CFT073 1039138 NP_753056.1 CDS torR NC_004431.1 1092002 1092694 R response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR complement(1092002..1092694) Escherichia coli CFT073 1039104 NP_753057.1 CDS torC NC_004431.1 1092776 1093996 D Escherichia coli K-12 ortholog: b0996; Escherichia coli O157:H7 ortholog: z1414; cytochrome c-type protein torC 1092776..1093996 Escherichia coli CFT073 1039281 NP_753058.1 CDS torA NC_004431.1 1093996 1096542 D Escherichia coli K-12 ortholog: b0997; Escherichia coli O157:H7 ortholog: z1415; trimethylamine-N-oxide reductase 1 1093996..1096542 Escherichia coli CFT073 1039106 NP_753059.2 CDS torD NC_004431.1 1096539 1097138 D TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1096539..1097138 Escherichia coli CFT073 1039357 NP_753060.1 CDS yccD NC_004431.1 1097494 1097799 R with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM complement(1097494..1097799) Escherichia coli CFT073 1039103 NP_753061.1 CDS cbpA NC_004431.1 1097799 1098719 R functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA complement(1097799..1098719) Escherichia coli CFT073 1039135 NP_753062.1 CDS agp NC_004431.1 1099254 1100210 D Escherichia coli K-12 ortholog: b1002; Escherichia coli O157:H7 ortholog: z1421; glucose-1-phosphatase/inositol phosphatase 1099254..1100210 Escherichia coli CFT073 1035752 NP_753063.1 CDS c1138 NC_004431.1 1100241 1100495 D Residues 21 to 84 of 84 are 96.87 pct identical to residues 350 to 413 of 413 from GenPept.129 : >gb|AAG55550.1|AE005294_5 (AE005294) periplasmic glucose-1-phosphatase [Escherichia coli O157:H7 EDL933]; hypothetical protein 1100241..1100495 Escherichia coli CFT073 1039141 NP_753064.1 CDS yccJ NC_004431.1 1100533 1100760 R Escherichia coli K-12 ortholog: b1003; Escherichia coli O157:H7 ortholog: z1422; hypothetical protein complement(1100533..1100760) Escherichia coli CFT073 1035751 NP_753065.1 CDS wrbA NC_004431.1 1100781 1101377 R stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA complement(1100781..1101377) Escherichia coli CFT073 1039126 NP_753066.1 CDS c1141 NC_004431.1 1101781 1101939 D hypothetical protein 1101781..1101939 Escherichia coli CFT073 1039117 NP_753067.1 CDS c1142 NC_004431.1 1101936 1102073 D hypothetical protein 1101936..1102073 Escherichia coli CFT073 1036820 NP_753068.1 CDS ycdG NC_004431.1 1102006 1103400 R Escherichia coli K-12 ortholog: b1006; Escherichia coli O157:H7 ortholog: z1505; purine permease ycdG complement(1102006..1103400) Escherichia coli CFT073 1039134 NP_753069.1 CDS c1144 NC_004431.1 1103355 1103909 R Escherichia coli K-12 ortholog: b1007; Escherichia coli O157:H7 ortholog: z1506; flavin:NADH reductase ycdH complement(1103355..1103909) Escherichia coli CFT073 1035755 NP_753070.1 CDS c1145 NC_004431.1 1103860 1104450 R Escherichia coli K-12 ortholog: b1008; Escherichia coli O157:H7 ortholog: z1507; hypothetical protein complement(1103860..1104450) Escherichia coli CFT073 1039177 NP_753071.3 CDS ycdJ NC_004431.1 1104460 1105287 R Escherichia coli K-12 ortholog: b1009; Escherichia coli O157:H7 ortholog: z1508; hypothetical protein complement(1104460..1105287) Escherichia coli CFT073 1035754 NP_753072.1 CDS ycdK NC_004431.1 1105268 1105654 R Escherichia coli K-12 ortholog: b1010; Escherichia coli O157:H7 ortholog: z1509; hypothetical protein complement(1105268..1105654) Escherichia coli CFT073 1039370 NP_753073.1 CDS ycdL NC_004431.1 1105666 1106400 R Escherichia coli K-12 ortholog: b1011; Escherichia coli O157:H7 ortholog: z1510; isochorismatase family protein ycdL complement(1105666..1106400) Escherichia coli CFT073 1039352 NP_753074.1 CDS c1149 NC_004431.1 1106358 1107539 R Escherichia coli K-12 ortholog: b1012; Escherichia coli O157:H7 ortholog: z1511; monooxygenase ycdM complement(1106358..1107539) Escherichia coli CFT073 1039358 NP_753075.1 CDS ycdC NC_004431.1 1107710 1108375 D Escherichia coli K-12 ortholog: b1013; Escherichia coli O157:H7 ortholog: z1512; transcriptional regulator YcdC 1107710..1108375 Escherichia coli CFT073 1039388 NP_753076.3 CDS putA NC_004431.1 1108415 1112443 R proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase complement(1108415..1112443) Escherichia coli CFT073 1040013 NP_753077.1 CDS c1152 NC_004431.1 1112432 1112641 D hypothetical protein 1112432..1112641 Escherichia coli CFT073 1039379 NP_753078.1 CDS c1153 NC_004431.1 1112529 1112720 R Residues 1 to 63 of 63 are 100.00 pct identical to residues 1 to 63 of 111 from GenPept.129 : >emb|CAA29142.1| (X05653) ORF (AA 1-111) [Escherichia coli]; hypothetical protein complement(1112529..1112720) Escherichia coli CFT073 1039412 NP_753079.1 CDS putP NC_004431.1 1112800 1114308 D Proline permease; Escherichia coli K-12 ortholog: b1015; Escherichia coli O157:H7 ortholog: z1515; Sodium/proline symporter 1112800..1114308 Escherichia coli CFT073 1039423 NP_753080.1 CDS c1155 NC_004431.1 1114592 1115359 D Escherichia coli K-12 ortholog: b1017; Escherichia coli O157:H7 ortholog: z1519; cytochrome 1114592..1115359 Escherichia coli CFT073 1039415 NP_753081.1 CDS ycdO NC_004431.1 1115417 1116544 D Escherichia coli K-12 ortholog: b1018; Escherichia coli O157:H7 ortholog: z1520; hypothetical protein 1115417..1116544 Escherichia coli CFT073 1036827 NP_753082.1 CDS ycdB NC_004431.1 1116550 1117821 D Escherichia coli K-12 ortholog: b1019; Escherichia coli O157:H7 ortholog: z1521; hypothetical protein 1116550..1117821 Escherichia coli CFT073 1039418 NP_753083.1 CDS c1158 NC_004431.1 1117958 1118092 R hypothetical protein complement(1117958..1118092) Escherichia coli CFT073 1039413 NP_753084.1 CDS phoH NC_004431.1 1118312 1119235 D Phosphate starvation-inducible protein psiH; Escherichia coli K-12 ortholog: b1020; Escherichia coli O157:H7 ortholog: z1522; hypothetical protein 1118312..1119235 Escherichia coli CFT073 1039402 NP_753085.1 CDS pgaD NC_004431.1 1119285 1119698 R in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export; PGA biosynthesis protein complement(1119285..1119698) Escherichia coli CFT073 1039447 NP_753086.1 CDS ycdQ NC_004431.1 1119700 1121025 R predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase complement(1119700..1121025) Escherichia coli CFT073 1039434 NP_753087.1 CDS pgaB NC_004431.1 1121018 1123036 R in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export; outer membrane N-deacetylase complement(1121018..1123036) Escherichia coli CFT073 1039403 NP_753088.1 CDS pgaA NC_004431.1 1123045 1125468 R outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA complement(1123045..1125468) Escherichia coli CFT073 1039425 NP_753089.1 CDS ycdT NC_004431.1 1125933 1127423 D Escherichia coli K-12 ortholog: b1025; Escherichia coli O157:H7 ortholog: z1527; hypothetical protein 1125933..1127423 Escherichia coli CFT073 1039416 NP_753090.1 CDS c1165 NC_004431.1 1127702 1128904 D Escherichia coli O157:H7 ortholog: z1559; P4 family integrase 1127702..1128904 Escherichia coli CFT073 1035745 NP_753091.1 CDS c1166 NC_004431.1 1129092 1130909 R Escherichia coli O157:H7 ortholog: z1560; hypothetical protein complement(1129092..1130909) Escherichia coli CFT073 1039464 NP_753092.1 CDS c1167 NC_004431.1 1131195 1131359 D Residues 8 to 54 of 54 are 76.59 pct identical to residues 37 to 83 of 90 from GenPept.129 : >gb|AAL72381.1| (AF386526) INSA [Shigella flexneri 2a]; hypothetical protein 1131195..1131359 Escherichia coli CFT073 1035741 NP_753093.1 CDS c1168 NC_004431.1 1131407 1131799 D Escherichia coli O157:H7 ortholog: z1562; hypothetical protein 1131407..1131799 Escherichia coli CFT073 1039414 NP_753094.1 CDS alpA NC_004431.1 1132071 1132319 D Escherichia coli K-12 ortholog: b2624; Escherichia coli O157:H7 ortholog: z1563; prophage CP4-57 regulatory protein alpA 1132071..1132319 Escherichia coli CFT073 1039489 NP_753095.1 CDS c1170 NC_004431.1 1132944 1134404 D Escherichia coli K-12 ortholog: b2625; Escherichia coli O157:H7 ortholog: z1565; hypothetical protein 1132944..1134404 Escherichia coli CFT073 1039452 NP_753096.1 CDS c1171 NC_004431.1 1135368 1135961 D Escherichia coli O157:H7 ortholog: z1567; hypothetical protein 1135368..1135961 Escherichia coli CFT073 1035750 NP_753097.1 CDS c1172 NC_004431.1 1136060 1136317 R hypothetical protein complement(1136060..1136317) Escherichia coli CFT073 1039471 NP_753098.1 CDS c1173 NC_004431.1 1136063 1136269 D Residues 19 to 68 of 68 are 83.99 pct identical to residues 204 to 253 of 287 from GenPept.129 : >gb|AAL22135.1| (AE008850) methyltransferase [Salmonella typhimurium LT2]; hypothetical protein 1136063..1136269 Escherichia coli CFT073 1039497 NP_753099.1 CDS c1174 NC_004431.1 1136438 1138438 R Residues 89 to 661 of 666 are 54.87 pct identical to residues 54 to 622 of 636 from GenPept.129 : >gb|AAL73391.1|AF419157_1 (AF419157) enterotoxin [Aeromonas hydrophila]; hypothetical protein complement(1136438..1138438) Escherichia coli CFT073 1039456 NP_753100.1 CDS c1175 NC_004431.1 1138353 1139519 R Residues 2 to 387 of 388 are 34.62 pct identical to residues 1 to 377 of 384 from GenPept.129 : >gb|AAK80912.1|AE007794_4 (AE007794) PLP-dependent aminotransferase, [Clostridium acetobutylicum]; aminotransferase complement(1138353..1139519) Escherichia coli CFT073 1039479 NP_753101.1 CDS c1176 NC_004431.1 1139941 1140564 R Fusion of Escherichia coli K-12 B3132 and B3136; Residues 94 to 207 of 207 are 80.70 pct identical to residues 268 to 381 of 384 from GenPept.129 : >gb|AAC76170.1| (AE000395) tagatose-6-phosphate aldose/ketose isomerase [Escherichia coli K12]; hypothetical protein complement(1139941..1140564) Escherichia coli CFT073 1035749 NP_753102.1 CDS c1183 NC_004431.1 1142429 1142953 D hypothetical protein 1142429..1142953 Escherichia coli CFT073 1039507 NP_753103.1 CDS c1184 NC_004431.1 1142992 1143417 D Escherichia coli O157:H7 ortholog: z1634; hypothetical protein 1142992..1143417 Escherichia coli CFT073 1039499 NP_753104.1 CDS c1185 NC_004431.1 1143016 1143180 R hypothetical protein complement(1143016..1143180) Escherichia coli CFT073 1039546 NP_753105.1 CDS c1186 NC_004431.1 1143727 1144956 R FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase complement(1143727..1144956) Escherichia coli CFT073 1039543 NP_753106.1 CDS fabG NC_004431.1 1144953 1145684 R Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(1144953..1145684) Escherichia coli CFT073 1040314 NP_753107.1 CDS c1188 NC_004431.1 1145684 1146148 R Escherichia coli O157:H7 ortholog: z4864; hypothetical protein complement(1145684..1146148) Escherichia coli CFT073 1036884 NP_753108.1 CDS c1189 NC_004431.1 1146145 1147323 R FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase complement(1146145..1147323) Escherichia coli CFT073 1040306 NP_753109.1 CDS c1190 NC_004431.1 1147316 1147900 R Escherichia coli O157:H7 ortholog: z4862; hypothetical protein complement(1147316..1147900) Escherichia coli CFT073 1040313 NP_753110.1 CDS c1191 NC_004431.1 1147897 1150215 R Escherichia coli O157:H7 ortholog: z4861; hypothetical protein complement(1147897..1150215) Escherichia coli CFT073 1035740 NP_753111.1 CDS c1192 NC_004431.1 1150184 1150789 R Escherichia coli O157:H7 ortholog: z4860; hypothetical protein complement(1150184..1150789) Escherichia coli CFT073 1040321 NP_753112.1 CDS c1193 NC_004431.1 1150786 1151208 R Escherichia coli O157:H7 ortholog: z4859; hypothetical protein complement(1150786..1151208) Escherichia coli CFT073 1040331 NP_753113.1 CDS c1194 NC_004431.1 1151212 1152834 R Escherichia coli O157:H7 ortholog: z4858; hypothetical protein complement(1151212..1152834) Escherichia coli CFT073 1035744 NP_753114.1 CDS c1195 NC_004431.1 1152806 1152928 R hypothetical protein complement(1152806..1152928) Escherichia coli CFT073 1040315 NP_753115.1 CDS c1196 NC_004431.1 1152879 1153256 R Escherichia coli O157:H7 ortholog: z4857; hypothetical protein complement(1152879..1153256) Escherichia coli CFT073 1040327 NP_753116.1 CDS c1197 NC_004431.1 1153219 1154577 R Escherichia coli O157:H7 ortholog: z4856; hypothetical protein complement(1153219..1154577) Escherichia coli CFT073 1035743 NP_753117.1 CDS c1198 NC_004431.1 1154574 1155158 R Escherichia coli O157:H7 ortholog: z4855; hypothetical protein complement(1154574..1155158) Escherichia coli CFT073 1040302 NP_753118.1 CDS c1199 NC_004431.1 1155160 1155411 R carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein complement(1155160..1155411) Escherichia coli CFT073 1040364 NP_753119.1 CDS c1200 NC_004431.1 1155423 1155680 R Escherichia coli O157:H7 ortholog: z4853; acyl carrier protein complement(1155423..1155680) Escherichia coli CFT073 1039903 NP_753120.1 CDS c1201 NC_004431.1 1155655 1156494 R Escherichia coli O157:H7 ortholog: z4852; phospholipid biosynthesis acyltransferase complement(1155655..1156494) Escherichia coli CFT073 1040322 NP_753121.1 CDS c1202 NC_004431.1 1156473 1157219 R Escherichia coli O157:H7 ortholog: z4851; hypothetical protein complement(1156473..1157219) Escherichia coli CFT073 1040330 NP_753122.1 CDS c1203 NC_004431.1 1157236 1158294 R Escherichia coli O157:H7 ortholog: z4850; O-methyltransferase complement(1157236..1158294) Escherichia coli CFT073 1035742 NP_753123.1 CDS c1204 NC_004431.1 1158359 1158748 R Escherichia coli O157:H7 ortholog: z4849; hypothetical protein complement(1158359..1158748) Escherichia coli CFT073 1040337 NP_753124.1 CDS c1205 NC_004431.1 1159313 1162039 D Residues 678 to 908 of 908 are 24.05 pct identical to residues 2464 to 2674 of 3535 from GenPept.129 : >gb|AAG03431.1|AE004443_9 (AE004443) probable hemagglutinin [Pseudomonas aeruginosa]; hypothetical protein 1159313..1162039 Escherichia coli CFT073 1040359 NP_753125.1 CDS c1206 NC_004431.1 1161999 1163231 D Residues 8 to 375 of 410 are 24.61 pct identical to residues 1490 to 1839 of 2535 from GenPept.129 : >emb|CAC91295.1| (AJ414152) hemolysin [Yersinia pestis]; hypothetical protein 1161999..1163231 Escherichia coli CFT073 1040325 NP_753126.1 CDS c1207 NC_004431.1 1163191 1164804 D Residues 13 to 409 of 537 are 50.72 pct identical to residues 1970 to 2381 of 2535 from GenPept.129 : >emb|CAC91295.1| (AJ414152) hemolysin [Yersinia pestis]; hypothetical protein 1163191..1164804 Escherichia coli CFT073 1040356 NP_753127.1 CDS c1208 NC_004431.1 1165325 1165702 D Residues 3 to 121 of 125 are 57.14 pct identical to residues 3098 to 3216 of 3295 from GenPept.129 : >emb|CAC89456.1| (AJ414143) adhesin [Yersinia pestis]; hypothetical protein 1165325..1165702 Escherichia coli CFT073 1040381 NP_753128.1 CDS c1209 NC_004431.1 1166202 1166597 D hypothetical protein 1166202..1166597 Escherichia coli CFT073 1040378 NP_753129.1 CDS c1210 NC_004431.1 1166395 1166571 R hypothetical protein complement(1166395..1166571) Escherichia coli CFT073 1040346 NP_753130.1 CDS c1213 NC_004431.1 1167823 1168386 D Residues 33 to 186 of 187 are 94.15 pct identical to residues 128 to 281 of 282 from GenPept.129 : >dbj|BAA75091.1| (AB021078) 61 pct identical to 126 residues of 138 aa protein sp:YTL1_SALTY[hypothetical 15.2kd protein near tlpA operon of S. typhimurium plasmid] [Plasmid ColIb-P9]; hypothetical protein 1167823..1168386 Escherichia coli CFT073 1040396 NP_753131.1 CDS c1214 NC_004431.1 1168463 1168702 R Residues 1 to 72 of 79 are 94.44 pct identical to residues 1 to 72 of 521 from GenPept.129 : >gb|AAA98156.1| (M37218) cea gene product [Plasmid pKY1]; Cea protein complement(1168463..1168702) Escherichia coli CFT073 1040400 NP_753132.1 CDS c1215 NC_004431.1 1169460 1169669 D Residues 1 to 68 of 69 are 97.05 pct identical to residues 69 to 136 of 139 from GenPept.129 : >gb|AAB59140.1| (J01566) entry exclusion protein 2 (exc2) [Plasmid ColE1]; entry exclusion protein 2 1169460..1169669 Escherichia coli CFT073 1040405 NP_753133.1 CDS c1216 NC_004431.1 1169792 1169947 R Residues 14 to 51 of 51 are 71.42 pct identical to residues 272 to 313 of 313 from GenPept.129 : >gb|AAL23539.1| (AE006471) cytoplasmic protein [Salmonella typhimurium LT2]; hypothetical protein complement(1169792..1169947) Escherichia coli CFT073 1040380 NP_753134.1 CDS c1217 NC_004431.1 1169968 1170276 R hypothetical protein complement(1169968..1170276) Escherichia coli CFT073 1040373 NP_753135.1 CDS c1218 NC_004431.1 1170358 1170861 R Residues 1 to 167 of 167 are 96.40 pct identical to residues 373 to 539 of 539 from GenPept.129 : >gb|AAL57569.1|AF453441_53 (AF453441) transposase [Escherichia coli]; hypothetical protein complement(1170358..1170861) Escherichia coli CFT073 1037012 NP_753136.1 CDS c1219 NC_004431.1 1170833 1171582 R Residues 1 to 237 of 249 are 96.20 pct identical to residues 133 to 369 of 539 from GenPept.129 : >gb|AAL57569.1|AF453441_53 (AF453441) transposase [Escherichia coli]; transposase complement(1170833..1171582) Escherichia coli CFT073 1037060 NP_753137.1 CDS c1220 NC_004431.1 1172485 1173561 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose-4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 1172485..1173561 Escherichia coli CFT073 1037008 NP_753138.1 CDS c1221 NC_004431.1 1173449 1173682 D hypothetical protein 1173449..1173682 Escherichia coli CFT073 1037028 NP_753139.1 CDS c1222 NC_004431.1 1174032 1174163 D hypothetical protein 1174032..1174163 Escherichia coli CFT073 1035737 NP_753140.1 CDS c1224 NC_004431.1 1174628 1175380 R Escherichia coli K-12 ortholog: b2089; Escherichia coli O157:H7 ortholog: z1573; transposase insF complement(1174628..1175380) Escherichia coli CFT073 1035739 NP_753141.1 CDS c1225 NC_004431.1 1175364 1175588 R Escherichia coli K-12 ortholog: b2088; transposase insE complement(1175364..1175588) Escherichia coli CFT073 1040406 NP_753142.1 CDS mchB NC_004431.1 1176756 1177049 D Possible fusion with mchI; Residues 23 to 97 of 97 are 100.00 pct identical to residues 1 to 75 of 75 from SwissProt.40 : >sp|Q9RM53|MCHB_ECOLI Microcin H47 precursor (MccH47); MchB protein 1176756..1177049 Escherichia coli CFT073 1039907 NP_753143.1 CDS mchC NC_004431.1 1177321 1178871 D Residues 1 to 516 of 516 are 73.44 pct identical to residues 9 to 524 of 524 from GenPept.129 : >gb|AAL08403.1| (AF063590) MceJ [Klebsiella pneumoniae]; MchC protein 1177321..1178871 Escherichia coli CFT073 1040409 NP_753144.1 CDS mchD NC_004431.1 1178897 1179349 D Residues 1 to 149 of 150 are 88.59 pct identical to residues 4 to 152 of 163 from GenPept.129 : >gb|AAL08402.1| (AF063590) MceI [Klebsiella pneumoniae]; MchD protein 1178897..1179349 Escherichia coli CFT073 1036982 NP_753145.1 CDS mchE NC_004431.1 1179502 1180776 D Residues 1 to 424 of 424 are 98.82 pct identical to residues 1 to 424 of 424 from SwissProt.40 : >sp|Q9EXN6|MCHE_ECOLI Microcin H47 secretion protein mchE; microcin H47 secretion protein 1179502..1180776 Escherichia coli CFT073 1036922 NP_753146.1 CDS mchF NC_004431.1 1180751 1182865 D ABC transporter; Residues 7 to 704 of 704 are 98.71 pct identical to residues 1 to 698 of 698 from SwissProt.40 : >sp|Q9EXN5|MCHF_ECOLI Probable microcin H47 secretion ATP-binding protein mchF; microcin H47 secretion ATP-binding protein 1180751..1182865 Escherichia coli CFT073 1036950 NP_753147.1 CDS c1233 NC_004431.1 1183572 1184258 R Residues 1 to 228 of 228 are 96.92 pct identical to residues 1 to 228 of 228 from GenPept.129 : >emb|CAC43418.1| (X16664) hypothetical protein [Escherichia coli]; hypothetical protein complement(1183572..1184258) Escherichia coli CFT073 1036879 NP_753148.1 CDS c1234 NC_004431.1 1184358 1184828 R Escherichia coli O157:H7 ortholog: z1633; hypothetical protein complement(1184358..1184828) Escherichia coli CFT073 1036904 NP_753149.1 CDS c1235 NC_004431.1 1185274 1185786 D Escherichia coli O157:H7 ortholog: z1634; hypothetical protein 1185274..1185786 Escherichia coli CFT073 1036910 NP_753150.1 CDS c1236 NC_004431.1 1186019 1186597 D Escherichia coli O157:H7 ortholog: z1635; hypothetical protein 1186019..1186597 Escherichia coli CFT073 1035732 NP_753151.1 CDS sfaC NC_004431.1 1186872 1187156 R Residues 22 to 94 of 94 are 93.15 pct identical to residues 5 to 77 of 77 from SwissProt.40 : >sp|P04743|PAPI_ECOLI Major pilus subunit operon regulatory protein; F1C and S fimbrial switch regulatory protein complement(1186872..1187156) Escherichia coli CFT073 1036837 NP_753152.1 CDS sfaB NC_004431.1 1187512 1187841 D Residues 1 to 102 of 109 are 82.35 pct identical to residues 1 to 102 of 104 from SwissProt.40 : >sp|P04744|PAPB_ECOLI MAJOR PILU SUBUNIT OPERON REGULATORY PROTEIN PAPB; F1C and S fimbrial switch regulatory protein 1187512..1187841 Escherichia coli CFT073 1036582 NP_753153.1 CDS focA NC_004431.1 1188213 1188755 D Escherichia coli K-12 ortholog: b4314; Escherichia coli O157:H7 ortholog: z5912; F1C major fimbrial subunit 1188213..1188755 Escherichia coli CFT073 1036891 NP_753154.1 CDS sfaD NC_004431.1 1188841 1189365 D Escherichia coli K-12 ortholog: b4315; Escherichia coli O157:H7 ortholog: z5913; minor F1C fimbrial subunit 1188841..1189365 Escherichia coli CFT073 1036876 NP_753155.1 CDS focC NC_004431.1 1189406 1190101 D Escherichia coli K-12 ortholog: b4316; Escherichia coli O157:H7 ortholog: z5914; F1C periplasmic chaperone 1189406..1190101 Escherichia coli CFT073 1036920 NP_753156.1 CDS focD NC_004431.1 1190123 1192801 D Escherichia coli K-12 ortholog: b4317; Escherichia coli O157:H7 ortholog: z5915; F1C fimbrial usher 1190123..1192801 Escherichia coli CFT073 1036693 NP_753157.1 CDS focF NC_004431.1 1192814 1193341 D Escherichia coli K-12 ortholog: b4318; Escherichia coli O157:H7 ortholog: z5916; F1C minor fimbrial subunit F 1192814..1193341 Escherichia coli CFT073 1035733 NP_753158.1 CDS focG NC_004431.1 1193363 1193866 D Escherichia coli K-12 ortholog: b4319; Escherichia coli O157:H7 ortholog: z5917; F1C minor fimbrial subunit protein G presursor 1193363..1193866 Escherichia coli CFT073 1036842 NP_753159.1 CDS focH NC_004431.1 1193817 1194827 D Residues 38 to 336 of 336 are 81.60 pct identical to residues 1 to 291 of 291 from SwissProt.40 : >sp|P13431|SFAH_ECOLI S-FIMBRIAL ADHESIN PROTEIN SFAH PRECURSOR; F1C fimbrial adhesin 1193817..1194827 Escherichia coli CFT073 1036402 NP_753160.1 CDS c1246 NC_004431.1 1195131 1195871 D Residues 21 to 238 of 246 are 27.35 pct identical to residues 12 to 226 of 232 from GenPept.129 : >emb|CAC93018.1| (AJ414153) conserved hypothetical protein [Yersinia pestis]; hypothetical protein 1195131..1195871 Escherichia coli CFT073 1034924 NP_753161.1 CDS focX NC_004431.1 1196018 1196569 D Residues 18 to 183 of 183 are 100.00 pct identical to residues 1 to 166 of 166 from SwissProt.40 : >sp|P42192|PRSX_ECOLI PRSX PROTEIN; regulatory protein 1196018..1196569 Escherichia coli CFT073 1034927 NP_753162.1 CDS c1248 NC_004431.1 1196895 1197932 R Residues 168 to 321 of 345 are 30.57 pct identical to residues 20 to 172 of 188 from GenPept.129 : >dbj|BAB06239.1| (AP001515) transposase related protein (20) [Bacillus halodurans]; hypothetical protein complement(1196895..1197932) Escherichia coli CFT073 1034929 NP_753163.1 CDS c1249 NC_004431.1 1197942 1198136 D hypothetical protein 1197942..1198136 Escherichia coli CFT073 1034930 NP_753164.1 CDS iroN NC_004431.1 1198162 1200339 D Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 1198162..1200339 Escherichia coli CFT073 1034931 NP_753165.1 CDS iroE NC_004431.1 1200384 1201340 R Residues 1 to 318 of 318 are 99.37 pct identical to residues 1 to 318 of 318 from GenPept.129 : >emb|CAC43425.1| (X16664) IroE protein [Escherichia coli]; IroE protein complement(1200384..1201340) Escherichia coli CFT073 1034932 NP_753166.1 CDS iroD NC_004431.1 1201425 1202654 R Residues 1 to 409 of 409 are 99.75 pct identical to residues 1 to 409 of 409 from GenPept.129 : >emb|CAC43426.1| (X16664) IroD protein [Escherichia coli]; ferric enterochelin esterase complement(1201425..1202654) Escherichia coli CFT073 1034933 NP_753167.1 CDS iroC NC_004431.1 1202758 1206495 R Residues 27 to 1231 of 1245 are 80.16 pct identical to residues 1 to 1209 of 1218 from GenPept.129 : >emb|CAD05883.1| (AL627276) ABC transporter protein [Salmonella enterica subsp. enterica serovar Typhi]; ABC transporter ATP-binding protein complement(1202758..1206495) Escherichia coli CFT073 1034934 NP_753168.1 CDS iroB NC_004431.1 1206557 1207720 R Escherichia coli O157:H7 ortholog: z1190; glucosyltransferase complement(1206557..1207720) Escherichia coli CFT073 1034935 NP_753169.1 CDS c1255 NC_004431.1 1208210 1208509 D hypothetical protein 1208210..1208509 Escherichia coli CFT073 1034936 NP_753170.1 CDS c1256 NC_004431.1 1208636 1209145 D Residues 18 to 169 of 169 are 94.07 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein 1208636..1209145 Escherichia coli CFT073 1034937 NP_753171.1 CDS c1257 NC_004431.1 1209273 1209635 R Residues 8 to 120 of 120 are 98.23 pct identical to residues 316 to 428 of 442 from MG1655 : b4278; hypothetical protein complement(1209273..1209635) Escherichia coli CFT073 1034938 NP_753172.1 CDS c1258 NC_004431.1 1210326 1210688 D hypothetical protein 1210326..1210688 Escherichia coli CFT073 1034939 NP_753173.1 CDS c1259 NC_004431.1 1210510 1210944 D Residues 1 to 139 of 144 are 50.71 pct identical to residues 104 to 242 of 258 from GenPept.129 : >gb|AAK18487.1|AF348706_176 (AF348706) orf, hypothetical [Shigella flexneri]; hypothetical protein 1210510..1210944 Escherichia coli CFT073 1034940 NP_753174.1 CDS c1260 NC_004431.1 1211507 1211965 R Escherichia coli O157:H7 ortholog: z4324; transposase complement(1211507..1211965) Escherichia coli CFT073 1034942 NP_753175.1 CDS c1261 NC_004431.1 1211977 1212342 R Residues 1 to 35 of 121 are 97.14 pct identical to residues 59 to 93 of 316 from GenPept.129 : >gb|AAK18437.1|AF348706_126 (AF348706) transposase [Shigella flexneri]; hypothetical protein complement(1211977..1212342) Escherichia coli CFT073 1034943 NP_753176.1 CDS c1262 NC_004431.1 1212504 1213394 R Escherichia coli O157:H7 ortholog: z3297; transposase IS629 complement(1212504..1213394) Escherichia coli CFT073 1034944 NP_753177.1 CDS c1263 NC_004431.1 1213391 1213717 R Escherichia coli O157:H7 ortholog: z2982; hypothetical protein complement(1213391..1213717) Escherichia coli CFT073 1034945 NP_753178.1 CDS c1264 NC_004431.1 1213743 1214183 R Residues 9 to 146 of 146 are 42.75 pct identical to residues 16 to 160 of 480 from GenPept.129 : >gb|AAG42314.1|AF306519_2 (AF306519) Tn5 transposase [Plasposon pTnMod2-OKm3]; hypothetical protein complement(1213743..1214183) Escherichia coli CFT073 1034946 NP_753179.1 CDS c1265 NC_004431.1 1214529 1216499 D Escherichia coli O157:H7 ortholog: z4911; outer membrane heme/hemoglobin receptor 1214529..1216499 Escherichia coli CFT073 1034947 NP_753180.1 CDS c1266 NC_004431.1 1216518 1217309 D Residues 2 to 260 of 263 are 27.61 pct identical to residues 1 to 261 of 268 from GenPept.129 : >emb|CAB84914.1| (AL162756) [Neisseria meningitidis Z2491]; hypothetical protein 1216518..1217309 Escherichia coli CFT073 1034948 NP_753181.1 CDS c1267 NC_004431.1 1217510 1218772 D Residues 20 to 413 of 420 are 28.81 pct identical to residues 1 to 390 of 395 from GenPept.129 : >dbj|BAB05509.1| (AP001513) BH1790; unknown conserved protein [Bacillus halodurans]; hypothetical protein 1217510..1218772 Escherichia coli CFT073 1034949 NP_753182.1 CDS c1268 NC_004431.1 1218879 1219061 R Residues 1 to 59 of 60 are 91.52 pct identical to residues 477 to 535 of 537 from GenPept.129 : >gb|AAG55715.1|AE005309_5 (AE005309) unknown in ISEc8 [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(1218879..1219061) Escherichia coli CFT073 1034950 NP_753183.1 CDS c1269 NC_004431.1 1219723 1220859 D Residues 25 to 254 of 378 are 43.04 pct identical to residues 83 to 310 of 327 from MG1655 : b0644; hypothetical protein 1219723..1220859 Escherichia coli CFT073 1034952 NP_753184.1 CDS c1270 NC_004431.1 1220895 1221437 D Residues 1 to 173 of 180 are 37.35 pct identical to residues 1 to 174 of 178 from GenPept.129 : >emb|CAC89258.1| (AJ414142) hypothetical protein [Yersinia pestis]; hypothetical protein 1220895..1221437 Escherichia coli CFT073 1034953 NP_753185.1 CDS c1271 NC_004431.1 1223811 1224107 R Residues 1 to 80 of 98 are 48.75 pct identical to residues 19 to 92 of 520 from GenPept.129 : >emb|CAA31541.1| (X13145) hsdM protein (AA 1-520) [Escherichia coli]; hypothetical protein complement(1223811..1224107) Escherichia coli CFT073 1034954 NP_753186.1 CDS c1272 NC_004431.1 1224407 1225279 D Escherichia coli K-12 ortholog: b1999; Escherichia coli O157:H7 ortholog: z1650; hypothetical protein 1224407..1225279 Escherichia coli CFT073 1034957 NP_753187.1 CDS c1273 NC_004431.1 1225454 1228729 D AG43; Sap; Escherichia coli K-12 ortholog: b2000; Escherichia coli O157:H7 ortholog: z1651; antigen 43 1225454..1228729 Escherichia coli CFT073 1034959 NP_753188.1 CDS c1274 NC_004431.1 1228844 1231366 D Escherichia coli K-12 ortholog: b2001; hypothetical protein 1228844..1231366 Escherichia coli CFT073 1034960 NP_753189.1 CDS c1275 NC_004431.1 1231442 1231897 D Residues 9 to 151 of 151 are 98.60 pct identical to residues 1 to 143 of 143 from GenPept.129 : >gb|AAK00476.1| (AF200692) unknown [Shigella flexneri 2a]; hypothetical protein 1231442..1231897 Escherichia coli CFT073 1034962 NP_753190.1 CDS c1276 NC_004431.1 1231915 1232043 D hypothetical protein 1231915..1232043 Escherichia coli CFT073 1034964 NP_753191.1 CDS c1277 NC_004431.1 1232016 1232204 R hypothetical protein complement(1232016..1232204) Escherichia coli CFT073 1034965 NP_753192.1 CDS c1278 NC_004431.1 1232308 1233129 D Escherichia coli K-12 ortholog: b0252; Escherichia coli O157:H7 ortholog: z1655; hypothetical protein 1232308..1233129 Escherichia coli CFT073 1034966 NP_753193.1 CDS c1279 NC_004431.1 1232314 1233222 R Residues 110 to 302 of 302 are 91.19 pct identical to residues 1 to 193 of 193 from GenPept.129 : >gb|AAL67348.1|AF447814_16 (AF447814) unknown [Escherichia coli]; hypothetical protein complement(1232314..1233222) Escherichia coli CFT073 1034967 NP_753194.1 CDS c1280 NC_004431.1 1233320 1233865 D Escherichia coli K-12 ortholog: b0248; Escherichia coli O157:H7 ortholog: z1656; hypothetical protein 1233320..1233865 Escherichia coli CFT073 1034968 NP_753195.1 CDS c1281 NC_004431.1 1233386 1234345 R Residues 1 to 319 of 319 are 92.78 pct identical to residues 1 to 319 of 319 from GenPept.129 : >gb|AAL67347.1|AF447814_15 (AF447814) unknown [Escherichia coli]; hypothetical protein complement(1233386..1234345) Escherichia coli CFT073 1034969 NP_753196.1 CDS c1282 NC_004431.1 1233881 1234357 D Escherichia coli K-12 ortholog: b2002; Escherichia coli O157:H7 ortholog: z1217; radC-like protein yeeS 1233881..1234357 Escherichia coli CFT073 1034970 NP_753197.1 CDS c1284 NC_004431.1 1236836 1237057 D Escherichia coli K-12 ortholog: b2003; Escherichia coli O157:H7 ortholog: z1218; hypothetical protein 1236836..1237057 Escherichia coli CFT073 1034972 NP_753198.1 CDS c1285 NC_004431.1 1237076 1237720 D Residues 178 to 214 of 214 are 78.37 pct identical to residues 1 to 37 of 37 from GenPept.129 : >gb|AAL57577.1|AF453442_6 (AF453442) unknown [Escherichia coli]; hypothetical protein 1237076..1237720 Escherichia coli CFT073 1034974 NP_753199.1 CDS c1286 NC_004431.1 1237770 1237961 D Residues 1 to 63 of 63 are 98.41 pct identical to residues 37 to 99 of 160 from GenPept.129 : >gb|AAL67343.1|AF447814_11 (AF447814) intergenic-region protein [Escherichia coli]; hypothetical protein 1237770..1237961 Escherichia coli CFT073 1034975 NP_753200.1 CDS c1287 NC_004431.1 1237977 1238144 D Residues 1 to 55 of 55 are 98.18 pct identical to residues 106 to 160 of 160 from GenPept.129 : >gb|AAL67343.1|AF447814_11 (AF447814) intergenic-region protein [Escherichia coli]; hypothetical protein 1237977..1238144 Escherichia coli CFT073 1034978 NP_753201.1 CDS c1288 NC_004431.1 1238191 1238571 D Escherichia coli K-12 ortholog: b2005; Escherichia coli O157:H7 ortholog: z5091; hypothetical protein 1238191..1238571 Escherichia coli CFT073 1034979 NP_753202.1 CDS c1289 NC_004431.1 1238568 1239056 D Escherichia coli O157:H7 ortholog: z5092; hypothetical protein 1238568..1239056 Escherichia coli CFT073 1034980 NP_753203.1 CDS c1290 NC_004431.1 1239076 1239273 D Escherichia coli O157:H7 ortholog: z1663; hypothetical protein 1239076..1239273 Escherichia coli CFT073 1034982 NP_753204.1 CDS c1291 NC_004431.1 1239426 1239935 D Residues 18 to 169 of 169 are 95.39 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein 1239426..1239935 Escherichia coli CFT073 1034983 NP_753205.1 CDS c1292 NC_004431.1 1240069 1240896 D Escherichia coli O157:H7 ortholog: z1664; hypothetical protein 1240069..1240896 Escherichia coli CFT073 1034984 NP_753206.1 CDS c1293 NC_004431.1 1240486 1240752 R Residues 42 to 88 of 88 are 87.23 pct identical to residues 8 to 54 of 75 from GenPept.129 : >gb|AAL08482.1| (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein complement(1240486..1240752) Escherichia coli CFT073 1034986 NP_753207.1 CDS c1294 NC_004431.1 1241249 1241404 R hypothetical protein complement(1241249..1241404) Escherichia coli CFT073 1034989 NP_753208.1 CDS ycdW NC_004431.1 1241384 1242322 D Escherichia coli K-12 ortholog: b1033; Escherichia coli O157:H7 ortholog: z1666; 2-hydroxyacid dehydrogenase ycdW 1241384..1242322 Escherichia coli CFT073 1034990 NP_753209.1 CDS ycdX NC_004431.1 1242377 1243114 D Escherichia coli K-12 ortholog: b1034; Escherichia coli O157:H7 ortholog: z1667; hydrolase 1242377..1243114 Escherichia coli CFT073 1034991 NP_753210.1 CDS ycdY NC_004431.1 1243138 1243692 D Escherichia coli K-12 ortholog: b1035; Escherichia coli O157:H7 ortholog: z1668; hypothetical protein 1243138..1243692 Escherichia coli CFT073 1034992 NP_753211.1 CDS ycdZ NC_004431.1 1243746 1244285 D Escherichia coli K-12 ortholog: b1036; Escherichia coli O157:H7 ortholog: z1669; hypothetical protein 1243746..1244285 Escherichia coli CFT073 1034993 NP_753212.1 CDS csgG NC_004431.1 1244350 1245183 R Escherichia coli K-12 ortholog: b1037; Escherichia coli O157:H7 ortholog: z1670; curli production assembly/transport component csgG complement(1244350..1245183) Escherichia coli CFT073 1034994 NP_753213.1 CDS csgF NC_004431.1 1245210 1245626 R nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF complement(1245210..1245626) Escherichia coli CFT073 1034995 NP_753214.1 CDS csgE NC_004431.1 1245651 1246040 R chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE complement(1245651..1246040) Escherichia coli CFT073 1034997 NP_753215.1 CDS csgD NC_004431.1 1246045 1246695 R activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD complement(1246045..1246695) Escherichia coli CFT073 1034998 NP_753216.1 CDS c1303 NC_004431.1 1246669 1246809 D hypothetical protein 1246669..1246809 Escherichia coli CFT073 1035001 NP_753217.1 CDS c1304 NC_004431.1 1247220 1247354 R Residues 4 to 43 of 44 are 92.50 pct identical to residues 1 to 40 of 79 from GenPept.129 : >dbj|BAB34841.1| (AP002554) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein complement(1247220..1247354) Escherichia coli CFT073 1035002 NP_753218.1 CDS csgB NC_004431.1 1247421 1247903 D CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1247421..1247903 Escherichia coli CFT073 1035004 NP_753219.1 CDS csgA NC_004431.1 1247944 1248402 D Escherichia coli K-12 ortholog: b1042; Escherichia coli O157:H7 ortholog: z1676; cryptic curlin major subunit 1247944..1248402 Escherichia coli CFT073 1035005 NP_753220.1 CDS csgC NC_004431.1 1248461 1248793 D involved in autoagglutination of curliated cells; not involved in production of curli fibers; autoagglutination protein 1248461..1248793 Escherichia coli CFT073 1035006 NP_753221.1 CDS ymdA NC_004431.1 1248914 1249225 D Escherichia coli K-12 ortholog: b1044; Escherichia coli O157:H7 ortholog: z1678; hypothetical protein 1248914..1249225 Escherichia coli CFT073 1035007 NP_753222.1 CDS ymdB NC_004431.1 1249320 1249853 D Escherichia coli K-12 ortholog: b1045; Escherichia coli O157:H7 ortholog: z1679; hypothetical protein 1249320..1249853 Escherichia coli CFT073 1035008 NP_753223.1 CDS ymdC NC_004431.1 1249795 1251276 D Escherichia coli K-12 ortholog: b1046; Escherichia coli O157:H7 ortholog: z1680; hypothetical protein 1249795..1251276 Escherichia coli CFT073 1035009 NP_753224.1 CDS mdoC NC_004431.1 1251284 1252441 R required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein complement(1251284..1252441) Escherichia coli CFT073 1035010 NP_753225.1 CDS c1312 NC_004431.1 1252486 1252629 R hypothetical protein complement(1252486..1252629) Escherichia coli CFT073 1035011 NP_753226.1 CDS mdoG NC_004431.1 1252817 1254370 D involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1252817..1254370 Escherichia coli CFT073 1035012 NP_753227.1 CDS mdoH NC_004431.1 1254333 1256906 D necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1254333..1256906 Escherichia coli CFT073 1035014 NP_753228.1 CDS c1315 NC_004431.1 1256915 1257139 D Residues 1 to 35 of 74 are 68.57 pct identical to residues 20 to 54 of 54 from GenPept.129 : >gb|AAC76157.1| (AE000394) orf, hypothetical protein [Escherichia coli K12]; hypothetical protein 1256915..1257139 Escherichia coli CFT073 1035015 NP_753229.1 CDS yceK NC_004431.1 1257078 1257305 D Escherichia coli K-12 ortholog: b1050; Escherichia coli O157:H7 ortholog: z1685; hypothetical protein 1257078..1257305 Escherichia coli CFT073 1035016 NP_753230.1 CDS c1317 NC_004431.1 1257287 1257661 R hypothetical protein complement(1257287..1257661) Escherichia coli CFT073 1035017 NP_753231.1 CDS msyB NC_004431.1 1257306 1257683 R Escherichia coli K-12 ortholog: b1051; Escherichia coli O157:H7 ortholog: z1686; hypothetical protein complement(1257306..1257683) Escherichia coli CFT073 1035018 NP_753232.1 CDS yceE NC_004431.1 1257763 1258989 R Confers resistance to fosfomycin and deoxycholate; drug efflux system protein MdtG complement(1257763..1258989) Escherichia coli CFT073 1035019 NP_753233.2 CDS htrB NC_004431.1 1259161 1260081 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(1259161..1260081) Escherichia coli CFT073 1035020 NP_753234.1 CDS yceA NC_004431.1 1260252 1261358 D ORF39.; Escherichia coli K-12 ortholog: b1055; Escherichia coli O157:H7 ortholog: z1691; hypothetical protein 1260252..1261358 Escherichia coli CFT073 1035021 NP_753235.1 CDS yceI NC_004431.1 1261400 1261975 R Escherichia coli K-12 ortholog: b1056; Escherichia coli O157:H7 ortholog: z1692; hypothetical protein complement(1261400..1261975) Escherichia coli CFT073 1035022 NP_753236.1 CDS c1323 NC_004431.1 1261979 1262557 R Escherichia coli K-12 ortholog: b1057; Escherichia coli O157:H7 ortholog: z1693; cytochrome b561 2 complement(1261979..1262557) Escherichia coli CFT073 1035023 NP_753237.1 CDS c1324 NC_004431.1 1262535 1262681 D hypothetical protein 1262535..1262681 Escherichia coli CFT073 1035024 NP_753238.1 CDS yceO NC_004431.1 1262807 1262944 R Escherichia coli K-12 ortholog: b1058; Escherichia coli O157:H7 ortholog: z1695; hypothetical protein complement(1262807..1262944) Escherichia coli CFT073 1035025 NP_753239.1 CDS solA NC_004431.1 1262965 1264083 R catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase complement(1262965..1264083) Escherichia coli CFT073 1035026 NP_753240.2 CDS bssS NC_004431.1 1264198 1264452 R BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS complement(1264198..1264452) Escherichia coli CFT073 1035027 NP_753241.2 CDS dinI NC_004431.1 1264742 1264987 R Escherichia coli K-12 ortholog: b1061; Escherichia coli O157:H7 ortholog: z1698; DNA damage-inducible protein I complement(1264742..1264987) Escherichia coli CFT073 1035028 NP_753242.1 CDS pyrC NC_004431.1 1265061 1266107 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(1265061..1266107) Escherichia coli CFT073 1035029 NP_753243.1 CDS yceB NC_004431.1 1266213 1266830 R Escherichia coli K-12 ortholog: b1063; Escherichia coli O157:H7 ortholog: z1700; hypothetical protein complement(1266213..1266830) Escherichia coli CFT073 1035030 NP_753244.1 CDS grxB NC_004431.1 1266907 1267554 R cofactor involved in the reduction of disulfides; glutaredoxin 2 complement(1266907..1267554) Escherichia coli CFT073 1035031 NP_753245.2 CDS yceL NC_004431.1 1267618 1268826 R Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH complement(1267618..1268826) Escherichia coli CFT073 1035032 NP_753246.1 CDS rimJ NC_004431.1 1269062 1269646 D Escherichia coli K-12 ortholog: b1066; Escherichia coli O157:H7 ortholog: z1703; Acetylating enzyme for N-terminal of ribosomal protein S5; ribosomal-protein-S5-alanine N-acetyltransferase 1269062..1269646 Escherichia coli CFT073 1035033 NP_753247.1 CDS yceH NC_004431.1 1269657 1270304 D G20.3; Escherichia coli K-12 ortholog: b1067; Escherichia coli O157:H7 ortholog: z1704; hypothetical protein 1269657..1270304 Escherichia coli CFT073 1035034 NP_753248.1 CDS c1337 NC_004431.1 1270867 1271265 R hypothetical protein complement(1270867..1271265) Escherichia coli CFT073 1035037 NP_753249.1 CDS mviN NC_004431.1 1271342 1272877 D Escherichia coli K-12 ortholog: b1069; Escherichia coli O157:H7 ortholog: z1707; virulence factor mviN-like protein 1271342..1272877 Escherichia coli CFT073 1035038 NP_753250.1 CDS flgN NC_004431.1 1272917 1273333 R Escherichia coli K-12 ortholog: b1070; Escherichia coli O157:H7 ortholog: z1708; flagellar synthesis protein FlgN complement(1272917..1273333) Escherichia coli CFT073 1035039 NP_753251.1 CDS flgM NC_004431.1 1273338 1273631 R regulates the flagellar specific sigma28 transcription factor; anti-sigma28 factor FlgM complement(1273338..1273631) Escherichia coli CFT073 1035040 NP_753252.1 CDS flgA NC_004431.1 1273707 1274366 R required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA complement(1273707..1274366) Escherichia coli CFT073 1035041 NP_753253.1 CDS flgB NC_004431.1 1274522 1274938 D with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal-body rod protein FlgB 1274522..1274938 Escherichia coli CFT073 1035042 NP_753254.1 CDS flgC NC_004431.1 1274942 1275346 D with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1274942..1275346 Escherichia coli CFT073 1035043 NP_753255.1 CDS flgD NC_004431.1 1275358 1276053 D acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1275358..1276053 Escherichia coli CFT073 1035044 NP_753256.1 CDS flgE NC_004431.1 1276078 1277283 D the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1276078..1277283 Escherichia coli CFT073 1035045 NP_753257.1 CDS flgF NC_004431.1 1277303 1278058 D FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1277303..1278058 Escherichia coli CFT073 1035046 NP_753258.1 CDS flgG NC_004431.1 1278230 1279012 D makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1278230..1279012 Escherichia coli CFT073 1035047 NP_753259.1 CDS flgH NC_004431.1 1279050 1279763 D part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1279050..1279763 Escherichia coli CFT073 1035048 NP_753260.1 CDS flgI NC_004431.1 1279772 1280872 D part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring biosynthesis protein FlgA 1279772..1280872 Escherichia coli CFT073 1035049 NP_753261.2 CDS flgJ NC_004431.1 1280872 1281813 D Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1280872..1281813 Escherichia coli CFT073 1035050 NP_753262.1 CDS flgK NC_004431.1 1281879 1283522 D with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1281879..1283522 Escherichia coli CFT073 1035051 NP_753263.1 CDS flgL NC_004431.1 1283534 1284487 D with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1283534..1284487 Escherichia coli CFT073 1035052 NP_753264.1 CDS rne NC_004431.1 1284682 1287867 R bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E complement(1284682..1287867) Escherichia coli CFT073 1035053 NP_753265.1 CDS c1354 NC_004431.1 1287948 1288322 D Escherichia coli K-12 ortholog: b1085; Escherichia coli O157:H7 ortholog: z1724; hypothetical protein 1287948..1288322 Escherichia coli CFT073 1035054 NP_753266.1 CDS rluC NC_004431.1 1288440 1289399 D catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1288440..1289399 Escherichia coli CFT073 1035055 NP_753267.2 CDS maf NC_004431.1 1289511 1290095 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(1289511..1290095) Escherichia coli CFT073 1035056 NP_753268.1 CDS c1357 NC_004431.1 1290107 1290235 R hypothetical protein complement(1290107..1290235) Escherichia coli CFT073 1035057 NP_753269.1 CDS yceD NC_004431.1 1290293 1290814 D G30K; Escherichia coli K-12 ortholog: b1088; Escherichia coli O157:H7 ortholog: z1727; hypothetical protein 1290293..1290814 Escherichia coli CFT073 1035058 NP_753270.1 CDS plsX NC_004431.1 1291120 1292190 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1291120..1292190 Escherichia coli CFT073 1035059 NP_753271.1 CDS fabH NC_004431.1 1292258 1293211 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1292258..1293211 Escherichia coli CFT073 1035060 NP_753272.1 CDS fabD NC_004431.1 1293227 1294156 D Escherichia coli K-12 ortholog: b1092; Escherichia coli O157:H7 ortholog: z1731; ACP S-malonyltransferase 1293227..1294156 Escherichia coli CFT073 1035061 NP_753273.1 CDS c1363 NC_004431.1 1295063 1295437 R hypothetical protein complement(1295063..1295437) Escherichia coli CFT073 1035062 NP_753274.1 CDS acpP NC_004431.1 1295117 1295353 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1295117..1295353 Escherichia coli CFT073 1035063 NP_753275.1 CDS fabF NC_004431.1 1295440 1296681 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1295440..1296681 Escherichia coli CFT073 1035064 NP_753276.1 CDS pabC NC_004431.1 1296801 1297583 D catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1296801..1297583 Escherichia coli CFT073 1035065 YP_004853805.1 CDS c1367 NC_004431.1 1297593 1297772 D hypothetical protein 1297593..1297772 Escherichia coli CFT073 1035066 YP_004853806.1 CDS c1368 NC_004431.1 1297612 1297746 D hypothetical protein 1297612..1297746 Escherichia coli CFT073 1035067 NP_753279.1 CDS yceG NC_004431.1 1297826 1298635 D Escherichia coli K-12 ortholog: b1097; Escherichia coli O157:H7 ortholog: z1736; hypothetical protein 1297826..1298635 Escherichia coli CFT073 1035068 NP_753280.1 CDS tmk NC_004431.1 1298625 1299266 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1298625..1299266 Escherichia coli CFT073 1035069 NP_753281.1 CDS holB NC_004431.1 1299263 1300267 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1299263..1300267 Escherichia coli CFT073 1035070 NP_753282.2 CDS ycfH NC_004431.1 1300278 1301075 D Escherichia coli K-12 ortholog: b1100; Escherichia coli O157:H7 ortholog: z1739; metallodependent hydrolase 1300278..1301075 Escherichia coli CFT073 1035071 NP_753283.1 CDS ptsG NC_004431.1 1301370 1302803 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunits IIBC 1301370..1302803 Escherichia coli CFT073 1035072 NP_753284.1 CDS fhuE NC_004431.1 1302863 1305052 R Outer-membrane receptor for Fe(III)-coprogen, Fe(III)-ferrioxamine B and Fe(III)-rhodotrulic acid; Escherichia coli K-12 ortholog: b1102; Escherichia coli O157:H7 ortholog: z1741; ferric-rhodotorulic acid outer membrane transporter complement(1302863..1305052) Escherichia coli CFT073 1035073 NP_753285.1 CDS c1375 NC_004431.1 1305085 1305255 R hypothetical protein complement(1305085..1305255) Escherichia coli CFT073 1035074 NP_753286.1 CDS ycfF NC_004431.1 1305368 1305745 D Escherichia coli K-12 ortholog: b1103; Escherichia coli O157:H7 ortholog: z1742; purine nucleoside phosphoramidase 1305368..1305745 Escherichia coli CFT073 1035075 NP_753287.1 CDS ycfL NC_004431.1 1305748 1306125 D Escherichia coli K-12 ortholog: b1104; Escherichia coli O157:H7 ortholog: z1743; hypothetical protein 1305748..1306125 Escherichia coli CFT073 1035076 NP_753288.1 CDS ycfM NC_004431.1 1306136 1306780 D Escherichia coli K-12 ortholog: b1105; Escherichia coli O157:H7 ortholog: z1744; hypothetical protein 1306136..1306780 Escherichia coli CFT073 1035077 NP_753289.1 CDS thiK NC_004431.1 1306761 1307585 D catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1306761..1307585 Escherichia coli CFT073 1035078 NP_753290.1 CDS nagZ NC_004431.1 1307596 1308621 D hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1307596..1308621 Escherichia coli CFT073 1035079 NP_753291.2 CDS ycfP NC_004431.1 1308644 1309186 D Escherichia coli K-12 ortholog: b1108; Escherichia coli O157:H7 ortholog: z1747; hypothetical protein 1308644..1309186 Escherichia coli CFT073 1035080 NP_753292.1 CDS ndh NC_004431.1 1309558 1310889 D Escherichia coli K-12 ortholog: b1109; Escherichia coli O157:H7 ortholog: z1748; NADH dehydrogenase 1309558..1310889 Escherichia coli CFT073 1035081 NP_753293.1 CDS ycfJ NC_004431.1 1311077 1311655 D Escherichia coli K-12 ortholog: b1110; Escherichia coli O157:H7 ortholog: z1749; hypothetical protein 1311077..1311655 Escherichia coli CFT073 1035083 NP_753294.1 CDS c1384 NC_004431.1 1311803 1312312 D Residues 18 to 169 of 169 are 95.39 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein 1311803..1312312 Escherichia coli CFT073 1035084 NP_753295.1 CDS ycfQ NC_004431.1 1312428 1313138 R Escherichia coli K-12 ortholog: b1111; Escherichia coli O157:H7 ortholog: z1750; transcriptional regulator YcfQ complement(1312428..1313138) Escherichia coli CFT073 1035085 NP_753296.1 CDS ycfR NC_004431.1 1313301 1313558 D Escherichia coli K-12 ortholog: b1112; Escherichia coli O157:H7 ortholog: z1751; hypothetical protein 1313301..1313558 Escherichia coli CFT073 1035087 NP_753297.1 CDS ycfS NC_004431.1 1313640 1314773 R Escherichia coli K-12 ortholog: b1113; Escherichia coli O157:H7 ortholog: z1752; hypothetical protein complement(1313640..1314773) Escherichia coli CFT073 1035088 NP_753298.1 CDS mfd NC_004431.1 1315400 1318255 R TRCF; Escherichia coli K-12 ortholog: b1114; Escherichia coli O157:H7 ortholog: z1754; transcription-repair coupling factor complement(1315400..1318255) Escherichia coli CFT073 1035091 NP_753299.1 CDS ycfT NC_004431.1 1318320 1319393 R Escherichia coli K-12 ortholog: b1115; Escherichia coli O157:H7 ortholog: z1756; hypothetical protein complement(1318320..1319393) Escherichia coli CFT073 1035092 NP_753300.1 CDS lolC NC_004431.1 1319654 1320853 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1319654..1320853 Escherichia coli CFT073 1035095 NP_753301.1 CDS lolD NC_004431.1 1320846 1321547 D outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1320846..1321547 Escherichia coli CFT073 1035096 NP_753302.1 CDS lolE NC_004431.1 1321547 1322791 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1321547..1322791 Escherichia coli CFT073 1035097 NP_753303.1 CDS ycfX NC_004431.1 1322820 1323731 D catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1322820..1323731 Escherichia coli CFT073 1035098 NP_753304.1 CDS cobB NC_004431.1 1323747 1324568 D Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1323747..1324568 Escherichia coli CFT073 1035099 NP_753305.1 CDS ycfZ NC_004431.1 1324706 1325494 R Escherichia coli K-12 ortholog: b1121; hypothetical protein complement(1324706..1325494) Escherichia coli CFT073 1035100 NP_753306.1 CDS ymfA NC_004431.1 1325491 1325994 R Escherichia coli K-12 ortholog: b1122; hypothetical protein complement(1325491..1325994) Escherichia coli CFT073 1035101 NP_753307.1 CDS potD NC_004431.1 1326010 1327056 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter periplasmic substrate-binding protein complement(1326010..1327056) Escherichia coli CFT073 1035102 NP_753308.1 CDS potC NC_004431.1 1327053 1327847 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1327053..1327847) Escherichia coli CFT073 1035103 NP_753309.1 CDS c1400 NC_004431.1 1328014 1329132 R Int(Lambda); Escherichia coli K-12 ortholog: b1140; Escherichia coli O157:H7 ortholog: z1764; prophage lambda integrase complement(1328014..1329132) Escherichia coli CFT073 1035104 NP_753310.1 CDS xisN NC_004431.1 1329101 1329379 R Escherichia coli O157:H7 ortholog: z1765; excisionase for prophage complement(1329101..1329379) Escherichia coli CFT073 1035105 NP_753311.1 CDS recE NC_004431.1 1329432 1331873 R Escherichia coli K-12 ortholog: b1350; exodeoxyribonuclease VIII complement(1329432..1331873) Escherichia coli CFT073 1035108 NP_753312.1 CDS c1403 NC_004431.1 1331937 1332482 D hypothetical protein 1331937..1332482 Escherichia coli CFT073 1035109 NP_753313.1 CDS ydfD NC_004431.1 1331967 1332167 R Escherichia coli K-12 ortholog: b1576; Escherichia coli O157:H7 ortholog: z6079; hypothetical protein complement(1331967..1332167) Escherichia coli CFT073 1035110 NP_753314.1 CDS dicB NC_004431.1 1332155 1332448 R Escherichia coli K-12 ortholog: b1575; Escherichia coli O157:H7 ortholog: z6078; division inhibition protein dicB complement(1332155..1332448) Escherichia coli CFT073 1035112 NP_753315.1 CDS c1406 NC_004431.1 1332454 1332609 D hypothetical protein 1332454..1332609 Escherichia coli CFT073 1035113 NP_753316.1 CDS ydfC NC_004431.1 1332912 1333130 R Escherichia coli K-12 ortholog: b1573; Escherichia coli O157:H7 ortholog: z6076; hypothetical protein complement(1332912..1333130) Escherichia coli CFT073 1035114 NP_753317.1 CDS ydfB NC_004431.1 1333160 1333330 R Escherichia coli K-12 ortholog: b1572; Escherichia coli O157:H7 ortholog: z1330; hypothetical protein complement(1333160..1333330) Escherichia coli CFT073 1035115 NP_753318.1 CDS ydfA NC_004431.1 1333290 1333526 R Escherichia coli K-12 ortholog: b1571; Escherichia coli O157:H7 ortholog: z2089; hypothetical protein complement(1333290..1333526) Escherichia coli CFT073 1035116 NP_753319.1 CDS c1410 NC_004431.1 1333711 1334130 R Residues 90 to 139 of 139 are 72.00 pct identical to residues 54 to 103 of 103 from GenPept.129 : >dbj|BAB35364.1| (AP002556) transcriptional regulator [Escherichia coli O157:H7]; hypothetical protein complement(1333711..1334130) Escherichia coli CFT073 1035117 NP_753320.1 CDS c1411 NC_004431.1 1334496 1334921 D Escherichia coli O157:H7 ortholog: z1335; hypothetical protein 1334496..1334921 Escherichia coli CFT073 1035118 NP_753321.1 CDS c1412 NC_004431.1 1335062 1336057 D Residues 97 to 331 of 331 are 79.14 pct identical to residues 177 to 400 of 400 from GenPept.129 : >gb|AAG55470.1|AE005288_1 (AE005288) unknown protein encoded by cryptic prophage CP-933M [Escherichia coli O157:H7 EDL933]; hypothetical protein 1335062..1336057 Escherichia coli CFT073 1035119 NP_753322.1 CDS c1413 NC_004431.1 1336098 1336520 D Escherichia coli O157:H7 ortholog: z2394; hypothetical protein 1336098..1336520 Escherichia coli CFT073 1035120 NP_753323.1 CDS c1414 NC_004431.1 1336521 1336934 D Residues 3 to 137 of 137 are 94.07 pct identical to residues 1 to 135 of 135 from GenPept.129 : >emb|CAD05603.1| (AL627272) bacteriophage protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein 1336521..1336934 Escherichia coli CFT073 1035121 NP_753324.1 CDS c1415 NC_004431.1 1336989 1337126 R hypothetical protein complement(1336989..1337126) Escherichia coli CFT073 1035122 NP_753325.1 CDS c1416 NC_004431.1 1337028 1337210 D hypothetical protein 1337028..1337210 Escherichia coli CFT073 1035123 NP_753326.1 CDS c1417 NC_004431.1 1337203 1337379 D Residues 1 to 58 of 58 are 86.20 pct identical to residues 21 to 78 of 78 from GenPept.129 : >dbj|BAB12674.1| (AP002527) yheA [Escherichia coli]; hypothetical protein 1337203..1337379 Escherichia coli CFT073 1035124 NP_753327.1 CDS c1418 NC_004431.1 1337824 1338042 D hypothetical protein 1337824..1338042 Escherichia coli CFT073 1035127 NP_753328.1 CDS c1419 NC_004431.1 1338495 1338626 D hypothetical protein 1338495..1338626 Escherichia coli CFT073 1035129 NP_753329.1 CDS c1420 NC_004431.1 1338498 1338659 R hypothetical protein complement(1338498..1338659) Escherichia coli CFT073 1035130 NP_753330.1 CDS c1421 NC_004431.1 1338915 1339193 D Residues 1 to 92 of 92 are 93.47 pct identical to residues 1 to 92 of 92 from GenPept.129 : >dbj|BAB34944.1| (AP002555) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 1338915..1339193 Escherichia coli CFT073 1035131 NP_753331.1 CDS c1422 NC_004431.1 1338933 1339112 R Residues 1 to 59 of 59 are 69.49 pct identical to residues 1 to 59 of 107 from GenPept.129 : >gb|AAG57026.1|AE005422_1 (AE005422) unknown protein encoded within prophage CP-933U [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(1338933..1339112) Escherichia coli CFT073 1035132 NP_753332.1 CDS c1423 NC_004431.1 1339195 1340244 D Escherichia coli K-12 ortholog: b1560; Escherichia coli O157:H7 ortholog: z3116; hypothetical protein 1339195..1340244 Escherichia coli CFT073 1035133 YP_004853807.1 CDS c1424 NC_004431.1 1340250 1340450 D hypothetical protein 1340250..1340450 Escherichia coli CFT073 1035134 NP_753334.1 CDS c1425 NC_004431.1 1340428 1340613 D Residues 1 to 60 of 61 are 94.99 pct identical to residues 58 to 117 of 124 from GenPept.129 : >gb|AAG55477.1|AE005288_8 (AE005288) endonuclease of cryptic prophage CP-933M [Escherichia coli O157:H7 EDL933]; hypothetical protein 1340428..1340613 Escherichia coli CFT073 1035135 NP_753335.1 CDS c1426 NC_004431.1 1340628 1341449 D Escherichia coli O157:H7 ortholog: z1345; cryptic prophage antitermination protein Q 1340628..1341449 Escherichia coli CFT073 1035136 NP_753336.1 CDS c1427 NC_004431.1 1341649 1342158 D Residues 18 to 169 of 169 are 94.07 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein 1341649..1342158 Escherichia coli CFT073 1035137 NP_753337.1 CDS c1428 NC_004431.1 1343053 1343184 D hypothetical protein 1343053..1343184 Escherichia coli CFT073 1035142 NP_753338.1 CDS ycgW NC_004431.1 1343465 1343800 R Escherichia coli K-12 ortholog: b1160; hypothetical protein complement(1343465..1343800) Escherichia coli CFT073 1035144 NP_753339.1 CDS c1430 NC_004431.1 1343926 1344075 R hypothetical protein complement(1343926..1344075) Escherichia coli CFT073 1035145 NP_753340.1 CDS c1431 NC_004431.1 1344049 1344249 D Residues 5 to 66 of 66 are 93.54 pct identical to residues 1 to 62 of 616 from GenPept.129 : >emb|CAC05558.1| (AJ251754) ORF616 [Escherichia coli]; hypothetical protein 1344049..1344249 Escherichia coli CFT073 1035146 NP_753341.1 CDS c1432 NC_004431.1 1344246 1344407 D Residues 8 to 53 of 53 are 86.95 pct identical to residues 572 to 617 of 617 from GenPept.129 : >gb|AAG57020.1|AE005421_8 (AE005421) unknown protein encoded within prophage CP-933U [Escherichia coli O157:H7 EDL933]; hypothetical protein 1344246..1344407 Escherichia coli CFT073 1035147 NP_753342.1 CDS c1433 NC_004431.1 1344452 1344772 D Escherichia coli K-12 ortholog: b0554; Escherichia coli O157:H7 ortholog: z3106; lambdoid prophage DLP12 lysis protein S 1344452..1344772 Escherichia coli CFT073 1035148 NP_753343.1 CDS ydfR NC_004431.1 1344777 1345121 D Escherichia coli K-12 ortholog: b1555; Escherichia coli O157:H7 ortholog: z2070; hypothetical protein 1344777..1345121 Escherichia coli CFT073 1035149 NP_753344.1 CDS c1435 NC_004431.1 1345087 1345365 R hypothetical protein complement(1345087..1345365) Escherichia coli CFT073 1035150 NP_753345.1 CDS c1436 NC_004431.1 1345465 1345998 D Escherichia coli K-12 ortholog: b1554; Escherichia coli O157:H7 ortholog: z1796; lysozyme from lambdoid prophage Qin 1345465..1345998 Escherichia coli CFT073 1035151 NP_753346.1 CDS c1437 NC_004431.1 1345980 1346462 D Escherichia coli K-12 ortholog: b0556; Escherichia coli O157:H7 ortholog: z0961; Rz endopeptidase from lambdoid prophage DLP12 1345980..1346462 Escherichia coli CFT073 1035153 NP_753347.1 CDS c1438 NC_004431.1 1346450 1346602 D Residues 1 to 50 of 50 are 92.00 pct identical to residues 1 to 50 of 50 from GenPept.129 : >dbj|BAB34245.1| (AP002553) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 1346450..1346602 Escherichia coli CFT073 1035154 NP_753348.1 CDS c1439 NC_004431.1 1346769 1347329 D Residues 1 to 185 of 186 are 74.59 pct identical to residues 1 to 183 of 184 from GenPept.129 : >gb|AAA82105.1| (L40418) alternate start at bp 59; ORF [Bacteriophage phi-80]; hypothetical protein 1346769..1347329 Escherichia coli CFT073 1035155 NP_753349.1 CDS ydfO NC_004431.1 1347632 1348057 R Escherichia coli K-12 ortholog: b1549; Escherichia coli O157:H7 ortholog: z1879; hypothetical protein complement(1347632..1348057) Escherichia coli CFT073 1035156 NP_753350.1 CDS c1441 NC_004431.1 1348095 1348244 D hypothetical protein 1348095..1348244 Escherichia coli CFT073 1035157 NP_753351.1 CDS c1442 NC_004431.1 1348100 1348333 R Escherichia coli O157:H7 ortholog: z2366; hypothetical protein complement(1348100..1348333) Escherichia coli CFT073 1035158 NP_753352.1 CDS c1443 NC_004431.1 1348481 1348606 D hypothetical protein 1348481..1348606 Escherichia coli CFT073 1035159 NP_753353.1 CDS c1444 NC_004431.1 1348728 1349237 D Escherichia coli K-12 ortholog: b1548; Escherichia coli O157:H7 ortholog: z2365; prophage Qin DNA packaging protein NU1-like protein 1348728..1349237 Escherichia coli CFT073 1035160 NP_753354.1 CDS c1445 NC_004431.1 1349209 1351137 D Escherichia coli O157:H7 ortholog: z2364; DNA packaging protein of prophage; terminase large subunit 1349209..1351137 Escherichia coli CFT073 1035164 NP_753355.1 CDS c1446 NC_004431.1 1351121 1351327 D Escherichia coli O157:H7 ortholog: z2363; DNA packaging protein of prophage 1351121..1351327 Escherichia coli CFT073 1035165 NP_753356.1 CDS c1447 NC_004431.1 1351324 1352916 D Escherichia coli O157:H7 ortholog: z2362; capsid protein of prophage 1351324..1352916 Escherichia coli CFT073 1035166 NP_753357.1 CDS c1448 NC_004431.1 1352906 1354411 D Escherichia coli O157:H7 ortholog: z2361; capsid assembly protein of prophage 1352906..1354411 Escherichia coli CFT073 1035168 NP_753358.1 CDS c1449 NC_004431.1 1354427 1354798 R hypothetical protein complement(1354427..1354798) Escherichia coli CFT073 1035169 NP_753359.1 CDS c1450 NC_004431.1 1354448 1354795 D Escherichia coli O157:H7 ortholog: z2360; capsid protein of prophage 1354448..1354795 Escherichia coli CFT073 1035170 NP_753360.1 CDS c1451 NC_004431.1 1354853 1355881 D Escherichia coli O157:H7 ortholog: z1888; capsid protein of prophage 1354853..1355881 Escherichia coli CFT073 1035171 NP_753361.1 CDS c1452 NC_004431.1 1355885 1356316 D Residues 17 to 143 of 143 are 40.15 pct identical to residues 1 to 124 of 124 from SwissProt.40 : >sp|P36276|YG78_BPP21 Hypothetical 13.5 kDa protein in GP7-GP8 intergenic region; hypothetical protein 1355885..1356316 Escherichia coli CFT073 1035174 NP_753362.1 CDS c1453 NC_004431.1 1356309 1356662 D Escherichia coli O157:H7 ortholog: z1890; head-tail joining protein of prophage 1356309..1356662 Escherichia coli CFT073 1035175 NP_753363.1 CDS c1454 NC_004431.1 1356678 1357211 D Escherichia coli O157:H7 ortholog: z0970; tail component of prophage 1356678..1357211 Escherichia coli CFT073 1035176 NP_753364.1 CDS c1455 NC_004431.1 1357208 1357603 D Escherichia coli O157:H7 ortholog: z1893; tail component of prophage 1357208..1357603 Escherichia coli CFT073 1035177 NP_753365.1 CDS c1456 NC_004431.1 1357611 1358357 D Escherichia coli O157:H7 ortholog: z3087; tail fiber component V of prophage 1357611..1358357 Escherichia coli CFT073 1035178 NP_753366.1 CDS c1457 NC_004431.1 1358354 1359004 R hypothetical protein complement(1358354..1359004) Escherichia coli CFT073 1035179 NP_753367.1 CDS c1458 NC_004431.1 1358376 1358807 D Escherichia coli O157:H7 ortholog: z2357; tail component of prophage 1358376..1358807 Escherichia coli CFT073 1035180 NP_753368.1 CDS c1459 NC_004431.1 1358834 1359247 D Escherichia coli O157:H7 ortholog: z2356; tail component of prophage 1358834..1359247 Escherichia coli CFT073 1035181 NP_753369.1 CDS c1460 NC_004431.1 1359228 1361789 D Escherichia coli O157:H7 ortholog: z2140; tail component of prophage 1359228..1361789 Escherichia coli CFT073 1035182 NP_753370.1 CDS c1461 NC_004431.1 1361786 1362115 D Escherichia coli O157:H7 ortholog: z3083; tail fiber component M of prophage 1361786..1362115 Escherichia coli CFT073 1035183 NP_753371.1 CDS c1462 NC_004431.1 1362115 1362813 D Escherichia coli O157:H7 ortholog: z2142; tail component of prophage 1362115..1362813 Escherichia coli CFT073 1035185 NP_753372.1 CDS c1463 NC_004431.1 1362166 1362969 R hypothetical protein complement(1362166..1362969) Escherichia coli CFT073 1035186 NP_753373.1 CDS c1464 NC_004431.1 1362864 1363562 D Escherichia coli O157:H7 ortholog: z3081; tail fiber component K of prophage 1362864..1363562 Escherichia coli CFT073 1035187 NP_753374.1 CDS c1465 NC_004431.1 1363526 1364140 D Escherichia coli O157:H7 ortholog: z6031; tail assembly protein of cryptic prophage 1363526..1364140 Escherichia coli CFT073 1035188 NP_753375.1 CDS c1466 NC_004431.1 1364484 1368176 D Escherichia coli O157:H7 ortholog: z2145; tail component of prophage 1364484..1368176 Escherichia coli CFT073 1035189 NP_753376.1 CDS lomP NC_004431.1 1368244 1368843 D Escherichia coli O157:H7 ortholog: z6028; Lom-like outer membrane protein of prophage 1368244..1368843 Escherichia coli CFT073 1035190 NP_753377.1 CDS c1468 NC_004431.1 1368995 1371058 D Residues 4 to 248 of 687 are 29.38 pct identical to residues 196 to 438 of 973 from GenPept.129 : >gb|AAG56007.1|AE005333_4 (AE005333) membrane protein of prophage CP-933X [Escherichia coli O157:H7 EDL933]; hypothetical protein 1368995..1371058 Escherichia coli CFT073 1035192 NP_753378.1 CDS c1469 NC_004431.1 1369339 1369503 R hypothetical protein complement(1369339..1369503) Escherichia coli CFT073 1035193 NP_753379.1 CDS c1470 NC_004431.1 1371055 1371333 D hypothetical protein 1371055..1371333 Escherichia coli CFT073 1035194 NP_753380.1 CDS c1471 NC_004431.1 1371343 1371636 D hypothetical protein 1371343..1371636 Escherichia coli CFT073 1035195 NP_753381.1 CDS c1472 NC_004431.1 1371423 1371797 R hypothetical protein complement(1371423..1371797) Escherichia coli CFT073 1035196 NP_753382.1 CDS c1473 NC_004431.1 1371747 1371872 D hypothetical protein 1371747..1371872 Escherichia coli CFT073 1035197 NP_753383.1 CDS c1474 NC_004431.1 1371829 1372494 R Escherichia coli K-12 ortholog: b0562; Escherichia coli O157:H7 ortholog: z1925; hypothetical protein complement(1371829..1372494) Escherichia coli CFT073 1035198 NP_753384.1 CDS ylcE NC_004431.1 1372554 1372820 D Escherichia coli K-12 ortholog: b0563; Escherichia coli O157:H7 ortholog: z1926; hypothetical protein 1372554..1372820 Escherichia coli CFT073 1035199 NP_753385.1 CDS potB NC_004431.1 1373052 1373915 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1373052..1373915) Escherichia coli CFT073 1035200 NP_753386.1 CDS potA NC_004431.1 1373899 1375035 R functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase protein complement(1373899..1375035) Escherichia coli CFT073 1035201 NP_753387.1 CDS c1478 NC_004431.1 1375014 1375265 R hypothetical protein complement(1375014..1375265) Escherichia coli CFT073 1035202 NP_753388.1 CDS pepT NC_004431.1 1375240 1376511 D catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1375240..1376511 Escherichia coli CFT073 1035204 NP_753389.1 CDS ycfD NC_004431.1 1376560 1377690 R Escherichia coli K-12 ortholog: b1128; Escherichia coli O157:H7 ortholog: z1833; hypothetical protein complement(1376560..1377690) Escherichia coli CFT073 1035205 NP_753390.1 CDS c1481 NC_004431.1 1377761 1378072 R hypothetical protein complement(1377761..1378072) Escherichia coli CFT073 1035208 YP_004853808.1 CDS c1482 NC_004431.1 1377903 1378040 R hypothetical protein complement(1377903..1378040) Escherichia coli CFT073 1035209 NP_753392.1 CDS c1483 NC_004431.1 1378215 1379159 D Escherichia coli O157:H7 ortholog: z1835; integrase of prophage 1378215..1379159 Escherichia coli CFT073 1035210 YP_004853809.1 CDS c1484 NC_004431.1 1378670 1378936 D hypothetical protein 1378670..1378936 Escherichia coli CFT073 1035211 NP_753394.1 CDS c1485 NC_004431.1 1379245 1379370 R hypothetical protein complement(1379245..1379370) Escherichia coli CFT073 1035212 NP_753395.1 CDS c1486 NC_004431.1 1379395 1379535 R hypothetical protein complement(1379395..1379535) Escherichia coli CFT073 1035213 NP_753396.1 CDS c1487 NC_004431.1 1379766 1381052 D Residues 114 to 279 of 428 are 55.36 pct identical to residues 20 to 196 of 247 from GenPept.129 : >dbj|BAB34999.1| (AP002555) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 1379766..1381052 Escherichia coli CFT073 1035214 NP_753397.1 CDS c1488 NC_004431.1 1381049 1381279 D Residues 3 to 61 of 76 are 52.54 pct identical to residues 2 to 60 of 63 from GenPept.129 : >dbj|BAB35002.1| (AP002555) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 1381049..1381279 Escherichia coli CFT073 1035215 NP_753398.1 CDS c1489 NC_004431.1 1381242 1381601 R hypothetical protein complement(1381242..1381601) Escherichia coli CFT073 1035217 NP_753399.1 CDS c1490 NC_004431.1 1381269 1381490 D hypothetical protein 1381269..1381490 Escherichia coli CFT073 1035218 NP_753400.1 CDS c1491 NC_004431.1 1381465 1381704 D hypothetical protein 1381465..1381704 Escherichia coli CFT073 1035220 NP_753401.1 CDS c1492 NC_004431.1 1381706 1381939 D hypothetical protein 1381706..1381939 Escherichia coli CFT073 1035221 NP_753402.1 CDS c1493 NC_004431.1 1381945 1382244 D Residues 1 to 99 of 99 are 82.82 pct identical to residues 1 to 99 of 99 from GenPept.129 : >dbj|BAB35004.1| (AP002555) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 1381945..1382244 Escherichia coli CFT073 1035222 NP_753403.1 CDS c1494 NC_004431.1 1381966 1382253 R hypothetical protein complement(1381966..1382253) Escherichia coli CFT073 1035223 NP_753404.1 CDS c1495 NC_004431.1 1382241 1383995 D Residues 116 to 561 of 584 are 49.34 pct identical to residues 269 to 725 of 763 from GenPept.129 : >emb|CAC89726.1| (AJ414145) primase [Yersinia pestis]; hypothetical protein 1382241..1383995 Escherichia coli CFT073 1035225 NP_753405.1 CDS c1496 NC_004431.1 1384284 1384541 D Escherichia coli O157:H7 ortholog: z1844; hypothetical protein 1384284..1384541 Escherichia coli CFT073 1035226 NP_753406.1 CDS c1497 NC_004431.1 1384538 1384948 D Escherichia coli O157:H7 ortholog: z1845; single stranded DNA-binding protein of prophage 1384538..1384948 Escherichia coli CFT073 1035228 NP_753407.1 CDS c1498 NC_004431.1 1385462 1385668 D hypothetical protein 1385462..1385668 Escherichia coli CFT073 1035229 NP_753408.1 CDS c1499 NC_004431.1 1385668 1386723 D Escherichia coli O157:H7 ortholog: z1888; capsid protein of prophage 1385668..1386723 Escherichia coli CFT073 1035230 NP_753409.1 CDS c1500 NC_004431.1 1386735 1387070 D Residues 6 to 105 of 111 are 36.63 pct identical to residues 13 to 110 of 115 from GenPept.129 : >gb|AAA32345.1| (M81255) capsid protein small subunit [Bacteriophage 21]; hypothetical protein 1386735..1387070 Escherichia coli CFT073 1035231 NP_753410.1 CDS c1501 NC_004431.1 1387083 1387496 D hypothetical protein 1387083..1387496 Escherichia coli CFT073 1035235 NP_753411.1 CDS c1502 NC_004431.1 1387524 1387706 R hypothetical protein complement(1387524..1387706) Escherichia coli CFT073 1035236 NP_753412.1 CDS c1503 NC_004431.1 1387752 1388093 D hypothetical protein 1387752..1388093 Escherichia coli CFT073 1035237 NP_753413.1 CDS c1504 NC_004431.1 1388123 1388284 D hypothetical protein 1388123..1388284 Escherichia coli CFT073 1035238 NP_753414.1 CDS c1505 NC_004431.1 1388373 1388654 D Escherichia coli O157:H7 ortholog: z1855; hypothetical protein 1388373..1388654 Escherichia coli CFT073 1035240 NP_753415.1 CDS c1506 NC_004431.1 1388397 1388834 R Escherichia coli O157:H7 ortholog: z1856; hypothetical protein complement(1388397..1388834) Escherichia coli CFT073 1035241 NP_753416.1 CDS c1507 NC_004431.1 1388812 1388952 D hypothetical protein 1388812..1388952 Escherichia coli CFT073 1035242 NP_753417.1 CDS phoQ NC_004431.1 1389209 1390669 R Escherichia coli K-12 ortholog: b1129; Escherichia coli O157:H7 ortholog: z1858; sensor protein PhoQ complement(1389209..1390669) Escherichia coli CFT073 1035243 NP_753418.1 CDS phoP NC_004431.1 1390669 1391340 R response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP complement(1390669..1391340) Escherichia coli CFT073 1035244 NP_753419.1 CDS purB NC_004431.1 1391510 1392880 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(1391510..1392880) Escherichia coli CFT073 1035246 NP_753420.1 CDS ycfC NC_004431.1 1392884 1393531 R HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein complement(1392884..1393531) Escherichia coli CFT073 1035247 NP_753421.2 CDS mnmA NC_004431.1 1393561 1394667 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(1393561..1394667) Escherichia coli CFT073 1035248 NP_753422.1 CDS c1513 NC_004431.1 1394721 1395182 R Escherichia coli K-12 ortholog: b1134; Escherichia coli O157:H7 ortholog: z1863; Nudix hydrolase ymfB complement(1394721..1395182) Escherichia coli CFT073 1035249 NP_753423.1 CDS c1514 NC_004431.1 1395370 1395726 R Residues 1 to 112 of 118 are 98.21 pct identical to residues 31 to 142 of 207 from GenPept.129 : >gb|AAG55961.1|AE005329_5 (AE005329) orf, hypothetical protein [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(1395370..1395726) Escherichia coli CFT073 1035250 NP_753424.1 CDS c1515 NC_004431.1 1395766 1395888 D hypothetical protein 1395766..1395888 Escherichia coli CFT073 1035251 NP_753425.1 CDS c1516 NC_004431.1 1395934 1397115 R hypothetical protein complement(1395934..1397115) Escherichia coli CFT073 1035253 NP_753426.1 CDS icdA NC_004431.1 1396018 1397268 D Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1396018..1397268 Escherichia coli CFT073 1035254 NP_753427.1 CDS c1518 NC_004431.1 1397313 1397456 D hypothetical protein 1397313..1397456 Escherichia coli CFT073 1035255 NP_753428.1 CDS c1519 NC_004431.1 1397370 1398512 R Int(Lambda); Escherichia coli K-12 ortholog: b1140; Escherichia coli O157:H7 ortholog: z1866; prophage lambda integrase complement(1397370..1398512) Escherichia coli CFT073 1035256 NP_753429.1 CDS c1520 NC_004431.1 1398656 1398982 D Escherichia coli O157:H7 ortholog: z2982; hypothetical protein 1398656..1398982 Escherichia coli CFT073 1035257 NP_753430.1 CDS c1521 NC_004431.1 1398979 1399869 D Escherichia coli O157:H7 ortholog: z3297; transposase IS629 1398979..1399869 Escherichia coli CFT073 1035258 NP_753431.1 CDS c1522 NC_004431.1 1400191 1400430 R Residues 1 to 79 of 79 are 40.00 pct identical to residues 42 to 121 of 121 from GenPept.129 : >emb|CAC83521.1| (AJ298298) hypothetical protein [Bacteriophage P27]; hypothetical protein complement(1400191..1400430) Escherichia coli CFT073 1035259 NP_753432.1 CDS c1523 NC_004431.1 1400456 1400824 R Escherichia coli O157:H7 ortholog: z1428; hypothetical protein complement(1400456..1400824) Escherichia coli CFT073 1035260 NP_753433.1 CDS c1524 NC_004431.1 1400733 1401473 R Residues 1 to 201 of 246 are 49.42 pct identical to residues 1 to 257 of 317 from SwissProt.40 : >sp|Q03544|VEAA_BPP22 Eaa protein; hypothetical protein complement(1400733..1401473) Escherichia coli CFT073 1035261 NP_753434.1 CDS c1525 NC_004431.1 1401470 1401721 R Residues 11 to 82 of 83 are 87.50 pct identical to residues 21 to 92 of 95 from GenPept.129 : >dbj|BAB87939.1| (AP004402) hypothetical protein [Stx2 converting bacteriophage I]; hypothetical protein complement(1401470..1401721) Escherichia coli CFT073 1035263 NP_753435.1 CDS c1526 NC_004431.1 1401681 1402241 R Residues 35 to 121 of 186 are 81.60 pct identical to residues 94 to 180 of 187 from GenPept.129 : >gb|AAG57028.1|AE005422_3 (AE005422) unknown protein encoded within prophage CP-933U [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(1401681..1402241) Escherichia coli CFT073 1035264 NP_753436.1 CDS c1527 NC_004431.1 1402232 1402507 R Residues 8 to 57 of 91 are 77.99 pct identical to residues 1 to 50 of 118 from GenPept.129 : >gb|AAG57254.1|AE005444_4 (AE005444) unknown protein encoded within prophage CP-933V [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(1402232..1402507) Escherichia coli CFT073 1035266 NP_753437.1 CDS c1528 NC_004431.1 1402488 1402817 R Residues 57 to 109 of 109 are 71.69 pct identical to residues 98 to 150 of 151 from GenPept.129 : >dbj|BAB12619.1| (AP002527) ycgB [Escherichia coli]; hypothetical protein complement(1402488..1402817) Escherichia coli CFT073 1035268 NP_753438.1 CDS c1529 NC_004431.1 1402870 1403625 R Residues 1 to 244 of 251 are 41.60 pct identical to residues 1 to 250 of 298 from SwissProt.40 : >sp|P55500|Y4IQ_RHISN INSERTION SEQUENCE ATP-BINDING PROTEIN Y4IQ/Y4ND/Y4SD; hypothetical protein complement(1402870..1403625) Escherichia coli CFT073 1035269 NP_753439.1 CDS c1530 NC_004431.1 1403622 1405121 R Residues 7 to 492 of 499 are 40.77 pct identical to residues 10 to 495 of 504 from SwissProt.40 : >sp|P55501|Y4JA_RHISN HYPOTHETICAL 57.2 KD PROTEIN Y4JA/Y4NE/Y4SE; hypothetical protein complement(1403622..1405121) Escherichia coli CFT073 1035270 NP_753440.1 CDS c1531 NC_004431.1 1405210 1405668 R Residues 1 to 124 of 152 are 85.48 pct identical to residues 1 to 124 of 238 from GenPept.129 : >gb|AAK28855.1|AF335538_7 (AF335538) unknown [Bacteriophage HK620]; hypothetical protein complement(1405210..1405668) Escherichia coli CFT073 1035271 NP_753441.1 CDS c1532 NC_004431.1 1405985 1406266 R Escherichia coli O157:H7 ortholog: z3369; hypothetical protein complement(1405985..1406266) Escherichia coli CFT073 1035273 NP_753442.1 CDS c1533 NC_004431.1 1406441 1406629 R Residues 3 to 62 of 62 are 96.66 pct identical to residues 1 to 60 of 60 from GenPept.129 : >gb|AAL02051.1| (AY048746) orf60a protein [Red recombinase plasmid pKD46]; hypothetical protein complement(1406441..1406629) Escherichia coli CFT073 1035274 NP_753443.1 CDS c1534 NC_004431.1 1406620 1407300 R Escherichia coli O157:H7 ortholog: z0951; exonuclease encoded by prophage complement(1406620..1407300) Escherichia coli CFT073 1035275 NP_753444.1 CDS c1535 NC_004431.1 1406629 1406940 D Residues 1 to 90 of 103 are 94.44 pct identical to residues 46 to 135 of 186 from MG1655 : b0538; hypothetical protein 1406629..1406940 Escherichia coli CFT073 1035276 NP_753445.1 CDS c1536 NC_004431.1 1407297 1408082 R Escherichia coli O157:H7 ortholog: z3366; recombination protein Bet of prophage complement(1407297..1408082) Escherichia coli CFT073 1035278 NP_753446.1 CDS gamW NC_004431.1 1408088 1408384 R Escherichia coli O157:H7 ortholog: z1438; host-nuclease inhibitor protein Gam of bacteriphage complement(1408088..1408384) Escherichia coli CFT073 1035279 NP_753447.1 CDS c1538 NC_004431.1 1408353 1408505 R Residues 1 to 50 of 50 are 95.99 pct identical to residues 1 to 50 of 50 from GenPept.129 : >dbj|BAB36422.1| (AP002560) host-nuclease inhibitor protein gam [Escherichia coli O157:H7]; hypothetical protein complement(1408353..1408505) Escherichia coli CFT073 1035281 NP_753448.1 CDS c1539 NC_004431.1 1408460 1408603 R Residues 1 to 47 of 47 are 97.87 pct identical to residues 1 to 47 of 47 from GenPept.129 : >gb|AAA96572.1| (J02459) kil(host-killing;54) [bacteriophage lambda]; hypothetical protein complement(1408460..1408603) Escherichia coli CFT073 1035282 NP_753449.1 CDS c1540 NC_004431.1 1408572 1408736 R Residues 1 to 54 of 54 are 98.14 pct identical to residues 1 to 54 of 54 from SwissProt.40 : >sp|P03044|RPC3_LAMBD REGULATORY PROTEIN CIII; lambda regulatory protein CIII complement(1408572..1408736) Escherichia coli CFT073 1035283 NP_753450.1 CDS c1541 NC_004431.1 1408809 1409177 R Escherichia coli O157:H7 ortholog: z3363; single-stranded DNA binding protein of prophage complement(1408809..1409177) Escherichia coli CFT073 1035285 NP_753451.1 CDS c1542 NC_004431.1 1409360 1409560 R Residues 1 to 66 of 66 are 98.48 pct identical to residues 1 to 66 of 66 from SwissProt.40 : >sp|P03703|VRAL_LAMBD Restriction inhibitor protein ral (Antirestriction protein); lambda ant-restriction protein complement(1409360..1409560) Escherichia coli CFT073 1035287 NP_753452.1 CDS c1543 NC_004431.1 1409774 1410355 D Escherichia coli O157:H7 ortholog: z3362; superinfection exclusion protein B of prophage 1409774..1410355 Escherichia coli CFT073 1035288 NP_753453.1 CDS c1544 NC_004431.1 1411081 1411833 R hypothetical protein complement(1411081..1411833) Escherichia coli CFT073 1035289 NP_753454.1 CDS c1545 NC_004431.1 1411830 1412387 R hypothetical protein complement(1411830..1412387) Escherichia coli CFT073 1035291 NP_753455.1 CDS c1546 NC_004431.1 1412427 1412849 R Residues 1 to 140 of 140 are 97.14 pct identical to residues 30 to 169 of 169 from GenPept.129 : >dbj|BAA84306.1| (AP000363) similar to CI repressor of bacteriophage lambda [Bacteriophage VT2-Sa]; repressor protein complement(1412427..1412849) Escherichia coli CFT073 1035292 NP_753456.1 CDS c1547 NC_004431.1 1413040 1413420 D Residues 56 to 126 of 126 are 100.00 pct identical to residues 1 to 71 of 71 from GenPept.129 : >dbj|BAA84307.1| (AP000363) similar to C2 of bacteriophage L [Bacteriophage VT2-Sa]; hypothetical protein 1413040..1413420 Escherichia coli CFT073 1035294 NP_753457.1 CDS c1548 NC_004431.1 1413562 1413858 D Escherichia coli O157:H7 ortholog: z1449; regulatory protein CII of bacteriophage 1413562..1413858 Escherichia coli CFT073 1035295 NP_753458.1 CDS c1549 NC_004431.1 1413891 1414790 D Escherichia coli O157:H7 ortholog: z1450; replication protein O of bacteriophage 1413891..1414790 Escherichia coli CFT073 1035296 NP_753459.1 CDS c1550 NC_004431.1 1414787 1415488 D Escherichia coli O157:H7 ortholog: z1451; replication protein P of bacteriophage 1414787..1415488 Escherichia coli CFT073 1035297 NP_753460.1 CDS c1551 NC_004431.1 1415485 1415775 D Escherichia coli O157:H7 ortholog: z3354; exclusion protein ren of prophage 1415485..1415775 Escherichia coli CFT073 1035300 NP_753461.1 CDS c1552 NC_004431.1 1415867 1416193 D Escherichia coli O157:H7 ortholog: z2982; hypothetical protein 1415867..1416193 Escherichia coli CFT073 1035301 NP_753462.1 CDS c1553 NC_004431.1 1416190 1417080 D Escherichia coli O157:H7 ortholog: z3297; transposase IS629 1416190..1417080 Escherichia coli CFT073 1035302 NP_753463.1 CDS c1554 NC_004431.1 1417162 1417602 D Escherichia coli O157:H7 ortholog: z3351; hypothetical protein 1417162..1417602 Escherichia coli CFT073 1035303 NP_753464.1 CDS c1555 NC_004431.1 1417569 1418126 D Escherichia coli O157:H7 ortholog: z1454; DNA N-6-adenine-methyltransferase of bacteriophage 1417569..1418126 Escherichia coli CFT073 1035304 NP_753465.1 CDS c1556 NC_004431.1 1418302 1418643 D Residues 1 to 113 of 113 are 61.01 pct identical to residues 3 to 112 of 112 from SwissProt.40 : >sp|Q38665|NINX_BPP22 protein ninX; hypothetical protein 1418302..1418643 Escherichia coli CFT073 1035305 NP_753466.1 CDS rus NC_004431.1 1418850 1419212 D DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 1418850..1419212 Escherichia coli CFT073 1035306 NP_753467.1 CDS c1558 NC_004431.1 1419209 1419349 D Residues 1 to 46 of 46 are 95.65 pct identical to residues 1 to 46 of 46 from SwissProt.40 : >sp|Q47272|YLCG_ECOLI Hypothetical protein ylcG in lambdoid DLP12 prophage region; hypothetical protein 1419209..1419349 Escherichia coli CFT073 1035307 NP_753468.1 CDS ybcQ NC_004431.1 1419420 1419818 D Escherichia coli K-12 ortholog: b0551; Escherichia coli O157:H7 ortholog: z1786; lambdoid prophage DLP12 antitermination protein Q 1419420..1419818 Escherichia coli CFT073 1035308 NP_753469.1 CDS nmpC NC_004431.1 1420007 1421149 R Escherichia coli K-12 ortholog: b0553; Escherichia coli O157:H7 ortholog: z2239; outer membrane porin protein nmpC complement(1420007..1421149) Escherichia coli CFT073 1035311 NP_753470.1 CDS c1561 NC_004431.1 1421678 1421893 D Escherichia coli K-12 ortholog: b0554; Escherichia coli O157:H7 ortholog: z3340; lambdoid prophage DLP12 lysis protein S 1421678..1421893 Escherichia coli CFT073 1035312 NP_753471.1 CDS ybcS NC_004431.1 1421893 1422390 D Escherichia coli K-12 ortholog: b0555; Escherichia coli O157:H7 ortholog: z0960; lysozyme from lambdoid prophage DLP12 1421893..1422390 Escherichia coli CFT073 1035313 NP_753472.1 CDS c1563 NC_004431.1 1422375 1422848 D Escherichia coli K-12 ortholog: b0556; Escherichia coli O157:H7 ortholog: z1473; Rz endopeptidase from lambdoid prophage DLP12 1422375..1422848 Escherichia coli CFT073 1035314 NP_753473.1 CDS ybcU NC_004431.1 1422880 1423221 R Escherichia coli K-12 ortholog: b0557; Escherichia coli O157:H7 ortholog: z1878; lambdoid prophage DLP12 Bor-like protein complement(1422880..1423221) Escherichia coli CFT073 1035316 NP_753474.1 CDS c1565 NC_004431.1 1423600 1423980 D Escherichia coli O157:H7 ortholog: z1799; tonB-like membrane protein encoded within prophage 1423600..1423980 Escherichia coli CFT073 1035317 NP_753475.1 CDS c1566 NC_004431.1 1423628 1423780 R hypothetical protein complement(1423628..1423780) Escherichia coli CFT073 1035318 NP_753476.1 CDS c1567 NC_004431.1 1424187 1424369 D hypothetical protein 1424187..1424369 Escherichia coli CFT073 1035319 NP_753477.1 CDS nohA NC_004431.1 1424932 1425480 D Escherichia coli K-12 ortholog: b1548; Escherichia coli O157:H7 ortholog: z1882; prophage Qin DNA packaging protein NU1-like protein 1424932..1425480 Escherichia coli CFT073 1035320 NP_753478.1 CDS c1569 NC_004431.1 1425428 1427380 D Escherichia coli O157:H7 ortholog: z2364; DNA packaging protein of prophage; terminase large subunit 1425428..1427380 Escherichia coli CFT073 1035321 NP_753479.1 CDS c1570 NC_004431.1 1427364 1427570 D Escherichia coli O157:H7 ortholog: z2363; DNA packaging protein of prophage 1427364..1427570 Escherichia coli CFT073 1035323 NP_753480.1 CDS c1571 NC_004431.1 1427567 1429159 D Escherichia coli O157:H7 ortholog: z2362; capsid protein of prophage 1427567..1429159 Escherichia coli CFT073 1035324 NP_753481.1 CDS c1572 NC_004431.1 1429149 1430654 D Escherichia coli O157:H7 ortholog: z2361; capsid assembly protein of prophage 1429149..1430654 Escherichia coli CFT073 1035325 NP_753482.1 CDS c1573 NC_004431.1 1430670 1431041 R hypothetical protein complement(1430670..1431041) Escherichia coli CFT073 1035326 NP_753483.1 CDS c1574 NC_004431.1 1430691 1431038 D Escherichia coli O157:H7 ortholog: z2360; capsid protein of prophage 1430691..1431038 Escherichia coli CFT073 1035327 NP_753484.1 CDS c1575 NC_004431.1 1431096 1432124 D Escherichia coli O157:H7 ortholog: z1888; capsid protein of prophage 1431096..1432124 Escherichia coli CFT073 1035328 NP_753485.1 CDS c1576 NC_004431.1 1432128 1432550 D Residues 17 to 140 of 140 are 100.00 pct identical to residues 1 to 124 of 124 from SwissProt.40 : >sp|P36276|YG78_BPP21 Hypothetical 13.5 kDa protein in GP7-GP8 intergenic region; hypothetical protein 1432128..1432550 Escherichia coli CFT073 1035329 NP_753486.1 CDS c1577 NC_004431.1 1432522 1432896 D Escherichia coli O157:H7 ortholog: z1890; head-tail joining protein of prophage 1432522..1432896 Escherichia coli CFT073 1035332 NP_753487.1 CDS c1578 NC_004431.1 1432908 1433486 D Escherichia coli O157:H7 ortholog: z3089; tail fiber component Z of prophage 1432908..1433486 Escherichia coli CFT073 1035333 NP_753488.1 CDS c1579 NC_004431.1 1433483 1433878 D Escherichia coli O157:H7 ortholog: z1893; tail component of prophage 1433483..1433878 Escherichia coli CFT073 1035334 NP_753489.1 CDS c1580 NC_004431.1 1433856 1434020 D Residues 1 to 53 of 54 are 96.22 pct identical to residues 1 to 53 of 256 from GenPept.129 : >gb|AAG55990.1|AE005331_3 (AE005331) tail component of prophage CP-933X [Escherichia coli O157:H7 EDL933]; tail protein 1433856..1434020 Escherichia coli CFT073 1035335 NP_753490.1 CDS c1581 NC_004431.1 1434181 1434612 R hypothetical protein complement(1434181..1434612) Escherichia coli CFT073 1035336 NP_753491.1 CDS c1583 NC_004431.1 1434638 1435060 D Escherichia coli O157:H7 ortholog: z1895; tail component of prophage 1434638..1435060 Escherichia coli CFT073 1035339 NP_753492.1 CDS c1584 NC_004431.1 1435042 1435476 D Escherichia coli O157:H7 ortholog: z1896; tail component of prophage 1435042..1435476 Escherichia coli CFT073 1035340 NP_753493.1 CDS c1585 NC_004431.1 1435469 1438030 D Escherichia coli O157:H7 ortholog: z2140; tail component of prophage 1435469..1438030 Escherichia coli CFT073 1035341 NP_753494.1 CDS c1586 NC_004431.1 1438260 1438910 R hypothetical protein complement(1438260..1438910) Escherichia coli CFT073 1035342 NP_753495.1 CDS c1587 NC_004431.1 1438356 1439054 D Escherichia coli O157:H7 ortholog: z0977; tail component of prophage 1438356..1439054 Escherichia coli CFT073 1035343 NP_753496.1 CDS c1588 NC_004431.1 1439060 1439803 D Escherichia coli O157:H7 ortholog: z0978; tail component of prophage 1439060..1439803 Escherichia coli CFT073 1035344 NP_753497.1 CDS c1589 NC_004431.1 1439740 1440372 D Escherichia coli O157:H7 ortholog: z0979; tail component of prophage 1439740..1440372 Escherichia coli CFT073 1035345 NP_753498.1 CDS c1590 NC_004431.1 1440433 1443915 D Escherichia coli O157:H7 ortholog: z2145; tail component of prophage 1440433..1443915 Escherichia coli CFT073 1035348 NP_753499.1 CDS c1591 NC_004431.1 1443968 1445635 D Residues 116 to 226 of 555 are 36.44 pct identical to residues 389 to 506 of 1122 from GenPept.129 : >gb|AAC74454.1| (AE000234) membrane protein [Escherichia coli K12]; hypothetical protein 1443968..1445635 Escherichia coli CFT073 1035349 NP_753500.1 CDS c1592 NC_004431.1 1444336 1444590 R Residues 3 to 82 of 84 are 48.23 pct identical to residues 65 to 149 of 206 from GenPept.129 : >gb|AAA96556.1| (J02459) orf206b [bacteriophage lambda]; hypothetical protein complement(1444336..1444590) Escherichia coli CFT073 1035350 NP_753501.1 CDS c1593 NC_004431.1 1445744 1446034 D hypothetical protein 1445744..1446034 Escherichia coli CFT073 1035351 NP_753502.1 CDS c1594 NC_004431.1 1446031 1446309 D hypothetical protein 1446031..1446309 Escherichia coli CFT073 1035354 NP_753503.1 CDS c1595 NC_004431.1 1446322 1446615 D hypothetical protein 1446322..1446615 Escherichia coli CFT073 1035355 NP_753504.1 CDS c1596 NC_004431.1 1446337 1446777 R hypothetical protein complement(1446337..1446777) Escherichia coli CFT073 1035356 NP_753505.1 CDS sitD NC_004431.1 1446707 1447564 R Residues 1 to 272 of 285 are 53.30 pct identical to residues 4 to 275 of 297 from SwissProt.40 : >sp|Q56955|YFED_YERPE Chelated iron transport system membrane protein yfeD; SitD protein complement(1446707..1447564) Escherichia coli CFT073 1035357 NP_753506.1 CDS sitC NC_004431.1 1447561 1448418 R Residues 1 to 276 of 285 are 65.94 pct identical to residues 2 to 277 of 294 from SwissProt.40 : >sp|Q56954|YFEC_YERPE Chelated iron transport system membrane protein yfeC; SitC protein complement(1447561..1448418) Escherichia coli CFT073 1035358 NP_753507.1 CDS sitB NC_004431.1 1448415 1449242 R Residues 7 to 263 of 275 are 62.03 pct identical to residues 11 to 276 of 296 from SwissProt.40 : >sp|Q56953|YFEB_YERPE Chelated iron transport system membrane protein yfeB; SitB protein complement(1448415..1449242) Escherichia coli CFT073 1035359 NP_753508.1 CDS sitA NC_004431.1 1449293 1450150 R Residues 2 to 263 of 285 are 62.97 pct identical to residues 3 to 257 of 293 from SwissProt.40 : >sp|Q57449|Y362_HAEIN PERIPLASMIC IRON-BINDING PROTEIN HI0362 PRECURSOR; SitA protein complement(1449293..1450150) Escherichia coli CFT073 1035361 NP_753509.1 CDS c1601 NC_004431.1 1450837 1451607 D hypothetical protein 1450837..1451607 Escherichia coli CFT073 1035363 NP_753510.1 CDS c1602 NC_004431.1 1452079 1452231 D Residues 1 to 50 of 50 are 98.00 pct identical to residues 5 to 54 of 54 from GenPept.129 : >gb|AAC48887.1| (AF017626) isocitrate dehydrogenase [Bacteriophage 21]; hypothetical protein 1452079..1452231 Escherichia coli CFT073 1035364 NP_753511.1 CDS ycgX NC_004431.1 1452493 1452897 R Escherichia coli K-12 ortholog: b1161; Escherichia coli O157:H7 ortholog: z1879; hypothetical protein complement(1452493..1452897) Escherichia coli CFT073 1035365 NP_753512.1 CDS ycgE NC_004431.1 1453118 1453849 R Escherichia coli K-12 ortholog: b1162; Escherichia coli O157:H7 ortholog: z3376; transcriptional regulator YcgE complement(1453118..1453849) Escherichia coli CFT073 1035366 NP_753513.1 CDS c1605 NC_004431.1 1453759 1453911 R hypothetical protein complement(1453759..1453911) Escherichia coli CFT073 1035367 NP_753514.1 CDS ycgF NC_004431.1 1454054 1455343 R Escherichia coli K-12 ortholog: b1163; hypothetical protein complement(1454054..1455343) Escherichia coli CFT073 1035370 NP_753515.1 CDS ycgZ NC_004431.1 1455579 1455815 D Escherichia coli K-12 ortholog: b1164; hypothetical protein 1455579..1455815 Escherichia coli CFT073 1035371 NP_753516.1 CDS c1608 NC_004431.1 1455792 1455965 R hypothetical protein complement(1455792..1455965) Escherichia coli CFT073 1035372 NP_753517.1 CDS ymgB NC_004431.1 1456159 1456425 D Escherichia coli K-12 ortholog: b1166; hypothetical protein 1456159..1456425 Escherichia coli CFT073 1035374 NP_753518.1 CDS c1610 NC_004431.1 1457126 1457977 D Escherichia coli O157:H7 ortholog: z0403; hypothetical protein 1457126..1457977 Escherichia coli CFT073 1035375 NP_753519.1 CDS c1611 NC_004431.1 1458073 1458327 D Residues 13 to 83 of 84 are 98.59 pct identical to residues 1 to 71 of 72 from SwissProt.40 : >sp|P58034|YMGF_ECOLI Hypothetical protein ymgF; hypothetical protein 1458073..1458327 Escherichia coli CFT073 1035376 NP_753520.1 CDS c1615 NC_004431.1 1459716 1460243 D Residues 1 to 47 of 175 are 97.87 pct identical to residues 42 to 88 of 338 from MG1655 : b1170; hypothetical protein 1459716..1460243 Escherichia coli CFT073 1035380 NP_753521.1 CDS ymgD NC_004431.1 1460301 1460636 R Escherichia coli K-12 ortholog: b1171; hypothetical protein complement(1460301..1460636) Escherichia coli CFT073 1035381 NP_753522.1 CDS c1617 NC_004431.1 1460640 1460984 R Escherichia coli K-12 ortholog: b1172; hypothetical protein complement(1460640..1460984) Escherichia coli CFT073 1035382 NP_753523.1 CDS c1618 NC_004431.1 1460986 1461159 R hypothetical protein complement(1460986..1461159) Escherichia coli CFT073 1035383 NP_753524.1 CDS c1619 NC_004431.1 1461577 1461903 D Residues 1 to 108 of 108 are 94.44 pct identical to residues 1462 to 1569 of 1569 from MG1655 : b2647; hypothetical protein 1461577..1461903 Escherichia coli CFT073 1035384 NP_753525.1 CDS c1620 NC_004431.1 1461949 1462134 D hypothetical protein 1461949..1462134 Escherichia coli CFT073 1035385 NP_753526.1 CDS minE NC_004431.1 1462276 1462542 R works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE complement(1462276..1462542) Escherichia coli CFT073 1035386 NP_753527.1 CDS minD NC_004431.1 1462546 1463358 R ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD complement(1462546..1463358) Escherichia coli CFT073 1035387 NP_753528.2 CDS minC NC_004431.1 1463382 1464077 R blocks the formation of polar Z-ring septums; septum formation inhibitor complement(1463382..1464077) Escherichia coli CFT073 1035388 NP_753529.1 CDS c1624 NC_004431.1 1464217 1464444 D hypothetical protein 1464217..1464444 Escherichia coli CFT073 1035389 NP_753530.1 CDS ycgJ NC_004431.1 1464597 1464965 D Escherichia coli K-12 ortholog: b1177; Escherichia coli O157:H7 ortholog: z1939; hypothetical protein 1464597..1464965 Escherichia coli CFT073 1035390 NP_753531.1 CDS ycgK NC_004431.1 1465085 1465486 R Escherichia coli K-12 ortholog: b1178; Escherichia coli O157:H7 ortholog: z1940; hypothetical protein complement(1465085..1465486) Escherichia coli CFT073 1035391 NP_753532.1 CDS ycgL NC_004431.1 1465695 1466021 D Escherichia coli K-12 ortholog: b1179; Escherichia coli O157:H7 ortholog: z1941; hypothetical protein 1465695..1466021 Escherichia coli CFT073 1035392 NP_753533.1 CDS c1628 NC_004431.1 1466093 1466752 D Escherichia coli K-12 ortholog: b1180; Escherichia coli O157:H7 ortholog: z1942; hypothetical protein 1466093..1466752 Escherichia coli CFT073 1035394 NP_753534.2 CDS ycgN NC_004431.1 1466844 1467290 D Escherichia coli K-12 ortholog: b1181; Escherichia coli O157:H7 ortholog: z1943; hypothetical protein 1466844..1467290 Escherichia coli CFT073 1035395 NP_753535.1 CDS c1630 NC_004431.1 1467497 1467778 R Residues 1 to 93 of 93 are 92.47 pct identical to residues 213 to 305 of 305 from MG1655 : b1182; hypothetical protein complement(1467497..1467778) Escherichia coli CFT073 1035399 NP_753536.1 CDS umuD NC_004431.1 1468083 1468502 D binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1468083..1468502 Escherichia coli CFT073 1035400 NP_753537.1 CDS umuC NC_004431.1 1468502 1469770 D binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1468502..1469770 Escherichia coli CFT073 1035402 NP_753538.2 CDS dsbB NC_004431.1 1469815 1470345 R disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B complement(1469815..1470345) Escherichia coli CFT073 1035403 NP_753539.2 CDS nhaB NC_004431.1 1470491 1472032 R involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter complement(1470491..1472032) Escherichia coli CFT073 1035404 NP_753540.1 CDS fadR NC_004431.1 1472254 1472973 D Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1472254..1472973 Escherichia coli CFT073 1035406 NP_753541.1 CDS c1636 NC_004431.1 1472961 1473086 R hypothetical protein complement(1472961..1473086) Escherichia coli CFT073 1035407 NP_753542.1 CDS ycgB NC_004431.1 1473136 1474668 R Escherichia coli K-12 ortholog: b1188; Escherichia coli O157:H7 ortholog: z1951; SpoVR family protein complement(1473136..1474668) Escherichia coli CFT073 1035408 NP_753543.2 CDS dadA NC_004431.1 1474998 1476296 D catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1474998..1476296 Escherichia coli CFT073 1035409 NP_753544.1 CDS dadX NC_004431.1 1476306 1477376 D catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1476306..1477376 Escherichia coli CFT073 1035411 NP_753545.1 CDS ycgO NC_004431.1 1477433 1479169 R the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter complement(1477433..1479169) Escherichia coli CFT073 1035412 NP_753546.1 CDS ldcA NC_004431.1 1479264 1480178 R catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A complement(1479264..1480178) Escherichia coli CFT073 1035414 YP_004853810.1 CDS c1642 NC_004431.1 1480151 1480339 D hypothetical protein 1480151..1480339 Escherichia coli CFT073 1035416 NP_753548.1 CDS mltE NC_004431.1 1480164 1480889 D Escherichia coli K-12 ortholog: b1193; Escherichia coli O157:H7 ortholog: z1956; membrane-bound lytic murein transglycosylase E 1480164..1480889 Escherichia coli CFT073 1035418 NP_753549.1 CDS ycgR NC_004431.1 1480891 1481625 R Escherichia coli K-12 ortholog: b1194; Escherichia coli O157:H7 ortholog: z1959; hypothetical protein complement(1480891..1481625) Escherichia coli CFT073 1035419 NP_753550.1 CDS ymgE NC_004431.1 1481793 1482080 D Escherichia coli K-12 ortholog: b1195; Escherichia coli O157:H7 ortholog: z1960; transglycosylase associated protein 1481793..1482080 Escherichia coli CFT073 1035421 NP_753551.1 CDS prrA NC_004431.1 1482130 1484121 R Escherichia coli O157:H7 ortholog: z1961; outer membrane receptor complement(1482130..1484121) Escherichia coli CFT073 1035422 NP_753552.1 CDS modD NC_004431.1 1484126 1484980 R involved in molybdenum transport; molybdenum transport protein ModD complement(1484126..1484980) Escherichia coli CFT073 1035423 NP_753553.1 CDS c1648 NC_004431.1 1484977 1485684 R Escherichia coli O157:H7 ortholog: z1963; hypothetical protein complement(1484977..1485684) Escherichia coli CFT073 1035424 NP_753554.1 CDS c1649 NC_004431.1 1485730 1485879 D hypothetical protein 1485730..1485879 Escherichia coli CFT073 1035425 NP_753555.1 CDS c1650 NC_004431.1 1485799 1486557 R Escherichia coli O157:H7 ortholog: z1964; iron compound ABC transporter, ATP-binding protein complement(1485799..1486557) Escherichia coli CFT073 1035426 NP_753556.1 CDS fecD NC_004431.1 1486554 1487450 R Escherichia coli K-12 ortholog: b4288; Escherichia coli O157:H7 ortholog: z1965; iron ABC transporter permease complement(1486554..1487450) Escherichia coli CFT073 1035427 NP_753557.1 CDS c1652 NC_004431.1 1487534 1488556 R Escherichia coli O157:H7 ortholog: z1966; hypothetical protein complement(1487534..1488556) Escherichia coli CFT073 1035429 NP_753558.1 CDS c1653 NC_004431.1 1488624 1488749 R hypothetical protein complement(1488624..1488749) Escherichia coli CFT073 1035430 NP_753559.1 CDS treA NC_004431.1 1488887 1490584 R periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase complement(1488887..1490584) Escherichia coli CFT073 1035431 NP_753560.1 CDS c1655 NC_004431.1 1490529 1490744 D hypothetical protein 1490529..1490744 Escherichia coli CFT073 1035432 NP_753561.1 CDS ycgC NC_004431.1 1490903 1492327 R phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL; dihydroxyacetone kinase subunit M complement(1490903..1492327) Escherichia coli CFT073 1035433 NP_753562.1 CDS c1657 NC_004431.1 1492332 1493042 R with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL complement(1492332..1493042) Escherichia coli CFT073 1035434 NP_753563.1 CDS ycgT NC_004431.1 1492975 1494075 R with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK complement(1492975..1494075) Escherichia coli CFT073 1035435 NP_753564.1 CDS c1659 NC_004431.1 1494264 1496192 D Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 1494264..1496192 Escherichia coli CFT073 1035436 NP_753565.1 CDS c1660 NC_004431.1 1496229 1496459 R hypothetical protein complement(1496229..1496459) Escherichia coli CFT073 1035437 NP_753566.1 CDS ychF NC_004431.1 1496597 1497688 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(1496597..1497688) Escherichia coli CFT073 1035439 NP_753567.1 CDS pth NC_004431.1 1497805 1498389 R Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase complement(1497805..1498389) Escherichia coli CFT073 1035440 NP_753568.1 CDS ychH NC_004431.1 1498667 1498945 D YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1498667..1498945 Escherichia coli CFT073 1035441 NP_753569.1 CDS ychM NC_004431.1 1499000 1500679 R role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; sulfate transporter YchM complement(1499000..1500679) Escherichia coli CFT073 1035442 NP_753570.1 CDS prsA NC_004431.1 1500804 1501817 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(1500804..1501817) Escherichia coli CFT073 1035443 NP_753571.1 CDS ipk NC_004431.1 1501902 1502753 R An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(1501902..1502753) Escherichia coli CFT073 1035444 NP_753572.1 CDS lolB NC_004431.1 1502753 1503442 R Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; molecular chaperone LolB complement(1502753..1503442) Escherichia coli CFT073 1035445 NP_753573.2 CDS hemA NC_004431.1 1503590 1504846 D catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1503590..1504846 Escherichia coli CFT073 1035446 NP_753574.1 CDS prfA NC_004431.1 1504888 1505970 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1504888..1505970 Escherichia coli CFT073 1035447 NP_753575.1 CDS hemK NC_004431.1 1505970 1506803 D HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1505970..1506803 Escherichia coli CFT073 1035448 NP_753576.1 CDS c1671 NC_004431.1 1506800 1507192 D Escherichia coli K-12 ortholog: b1213; Escherichia coli O157:H7 ortholog: z1984; transcriptional regulator 1506800..1507192 Escherichia coli CFT073 1035449 NP_753577.1 CDS ychA NC_004431.1 1507196 1508005 D Escherichia coli K-12 ortholog: b1214; Escherichia coli O157:H7 ortholog: z1985; transcriptional regulator 1507196..1508005 Escherichia coli CFT073 1035450 NP_753578.1 CDS c1673 NC_004431.1 1508002 1508964 R hypothetical protein complement(1508002..1508964) Escherichia coli CFT073 1035451 NP_753579.1 CDS kdsA NC_004431.1 1508041 1508895 D catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1508041..1508895 Escherichia coli CFT073 1035452 NP_753580.1 CDS c1675 NC_004431.1 1509044 1509322 R Escherichia coli O157:H7 ortholog: z4955; hypothetical protein complement(1509044..1509322) Escherichia coli CFT073 1035453 NP_753581.1 CDS chaA NC_004431.1 1509561 1510748 R Escherichia coli K-12 ortholog: b1216; Escherichia coli O157:H7 ortholog: z1991; calcium/sodium:proton antiporter complement(1509561..1510748) Escherichia coli CFT073 1035454 NP_753582.1 CDS chaB NC_004431.1 1510931 1511161 D in Escherichia coli this protein ly regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 1510931..1511161 Escherichia coli CFT073 1035455 NP_753583.1 CDS chaC NC_004431.1 1511271 1512002 D Escherichia coli K-12 ortholog: b1218; Escherichia coli O157:H7 ortholog: z1993; cation transport protein chaC 1511271..1512002 Escherichia coli CFT073 1035457 NP_753584.1 CDS ychN NC_004431.1 1512046 1512399 R Escherichia coli K-12 ortholog: b1219; Escherichia coli O157:H7 ortholog: z1994; hypothetical protein complement(1512046..1512399) Escherichia coli CFT073 1035458 NP_753585.1 CDS ychP NC_004431.1 1512584 1513978 D Escherichia coli K-12 ortholog: b1220; Escherichia coli O157:H7 ortholog: z1995; hypothetical protein 1512584..1513978 Escherichia coli CFT073 1035459 NP_753586.1 CDS narL NC_004431.1 1513979 1514695 R two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL complement(1513979..1514695) Escherichia coli CFT073 1035460 NP_753587.1 CDS narX NC_004431.1 1514622 1516418 R Escherichia coli K-12 ortholog: b1222; Escherichia coli O157:H7 ortholog: z1998; nitrate/nitrite sensor protein NarX complement(1514622..1516418) Escherichia coli CFT073 1035461 NP_753588.1 CDS c1683 NC_004431.1 1516444 1516662 D hypothetical protein 1516444..1516662 Escherichia coli CFT073 1035462 NP_753589.1 CDS narK NC_004431.1 1516751 1518148 D Nitrite facilitator 1; Escherichia coli K-12 ortholog: b1223; Escherichia coli O157:H7 ortholog: z2000; nitrite extrusion protein 1 1516751..1518148 Escherichia coli CFT073 1035463 NP_753590.1 CDS narG NC_004431.1 1518541 1522284 D Escherichia coli K-12 ortholog: b1224; Escherichia coli O157:H7 ortholog: z2001; respiratory nitrate reductase 1 subunit alpha 1518541..1522284 Escherichia coli CFT073 1035464 NP_753591.1 CDS narH NC_004431.1 1522281 1523819 D Escherichia coli K-12 ortholog: b1225; Escherichia coli O157:H7 ortholog: z2002; respiratory nitrate reductase 1 subunit beta 1522281..1523819 Escherichia coli CFT073 1035465 NP_753592.1 CDS narJ NC_004431.1 1523816 1524526 D Escherichia coli K-12 ortholog: b1226; Escherichia coli O157:H7 ortholog: z2003; respiratory nitrate reductase 1 subunit delta 1523816..1524526 Escherichia coli CFT073 1035466 NP_753593.1 CDS narI NC_004431.1 1524526 1525203 D Escherichia coli K-12 ortholog: b1227; Escherichia coli O157:H7 ortholog: z2004; respiratory nitrate reductase 1 subunit gamma 1524526..1525203 Escherichia coli CFT073 1035467 NP_753594.1 CDS c1689 NC_004431.1 1525279 1526322 D Residues 176 to 347 of 347 are 80.81 pct identical to residues 4 to 175 of 175 from GenPept.129 : >emb|CAA21325.1| (AL031866) ORF3, len: 175 aa,similar to C-terminal end of XCU70053_2 Xanthomonas campestris gumO (435 aa), possible frameshift, this ORF is the prolongation of ORF 4 also similar to XCU70053_2. Fasta score: opt: 367, E(): 1.8e-17 39.5%identity in 172 aa overlap [Yersinia pestis]; hypothetical protein 1525279..1526322 Escherichia coli CFT073 1035468 NP_753595.1 CDS c1690 NC_004431.1 1526319 1527335 D Escherichia coli K-12 ortholog: b0868; Escherichia coli O157:H7 ortholog: z1102; hypothetical protein 1526319..1527335 Escherichia coli CFT073 1035469 NP_753596.1 CDS c1691 NC_004431.1 1527313 1528119 D Residues 1 to 268 of 268 are 69.02 pct identical to residues 1 to 268 of 268 from GenPept.129 : >emb|CAC90793.1| (AJ414150) conserved hypothetical protein [Yersinia pestis]; gumP-like protein 1527313..1528119 Escherichia coli CFT073 1035471 NP_753597.1 CDS c1692 NC_004431.1 1528116 1529402 D Residues 1 to 424 of 428 are 66.03 pct identical to residues 1 to 424 of 428 from GenPept.129 : >emb|CAC90794.1| (AJ414150) coenzyme synthetase [Yersinia pestis]; hypothetical protein 1528116..1529402 Escherichia coli CFT073 1035472 NP_753598.1 CDS c1693 NC_004431.1 1529387 1530001 D Residues 24 to 188 of 204 are 27.52 pct identical to residues 23 to 198 of 219 from GenPept.129 : >gb|AAK79457.1|AE007659_12 (AE007659) Protein of phosphatidic acid phosphatase family, YNBD E.coli ortholog [Clostridium acetobutylicum]; hypothetical protein 1529387..1530001 Escherichia coli CFT073 1035473 NP_753599.1 CDS c1694 NC_004431.1 1529994 1531118 D Residues 12 to 235 of 374 are 32.46 pct identical to residues 19 to 246 of 317 from GenPept.129 : >dbj|BAB48523.1| (AP002996) hypothetical protein [Mesorhizobium loti]; hypothetical protein 1529994..1531118 Escherichia coli CFT073 1035474 NP_753600.1 CDS c1695 NC_004431.1 1531105 1532196 D Residues 23 to 359 of 363 are 24.20 pct identical to residues 19 to 357 of 359 from GenPept.129 : >dbj|BAA18502.1| (D90914) delta-6 desaturase [Synechocystis sp. PCC 6803]; hypothetical protein 1531105..1532196 Escherichia coli CFT073 1035475 NP_753601.1 CDS purU NC_004431.1 1532753 1533595 R produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase complement(1532753..1533595) Escherichia coli CFT073 1035478 NP_753602.2 CDS ychJ NC_004431.1 1533645 1534103 R Escherichia coli K-12 ortholog: b1233; Escherichia coli O157:H7 ortholog: z2009; hypothetical protein complement(1533645..1534103) Escherichia coli CFT073 1035479 NP_753603.1 CDS ychK NC_004431.1 1534177 1535121 D Escherichia coli K-12 ortholog: b1234; Escherichia coli O157:H7 ortholog: z2010; hypothetical protein 1534177..1535121 Escherichia coli CFT073 1035480 NP_753604.1 CDS hnr NC_004431.1 1535213 1536226 D Escherichia coli K-12 ortholog: b1235; Escherichia coli O157:H7 ortholog: z2011; response regulator of RpoS 1535213..1536226 Escherichia coli CFT073 1035481 NP_753605.1 CDS galU NC_004431.1 1536428 1537336 D together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase 1536428..1537336 Escherichia coli CFT073 1035482 NP_753606.1 CDS hns NC_004431.1 1537480 1537893 R Histone-like protein HLP-II; Escherichia coli K-12 ortholog: b1237; Escherichia coli O157:H7 ortholog: z2013; global DNA-binding transcriptional dual regulator H-NS complement(1537480..1537893) Escherichia coli CFT073 1035483 NP_753607.1 CDS c1702 NC_004431.1 1537985 1538113 R hypothetical protein complement(1537985..1538113) Escherichia coli CFT073 1035484 NP_753608.1 CDS tdk NC_004431.1 1538497 1539114 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1538497..1539114 Escherichia coli CFT073 1035485 NP_753609.1 CDS c1704 NC_004431.1 1539241 1540446 R Escherichia coli K-12 ortholog: b4278; transposase insG complement(1539241..1540446) Escherichia coli CFT073 1035486 NP_753610.1 CDS adhE NC_004431.1 1540572 1543247 R Escherichia coli K-12 ortholog: b1241; Escherichia coli O157:H7 ortholog: z2016; multifunctional; bifunctional acetaldehyde-CoA/alcohol dehydrogenase complement(1540572..1543247) Escherichia coli CFT073 1035487 NP_753611.1 CDS ychE NC_004431.1 1543724 1544371 D Escherichia coli K-12 ortholog: b1242; Escherichia coli O157:H7 ortholog: z2017; hypothetical protein 1543724..1544371 Escherichia coli CFT073 1035488 NP_753612.1 CDS oppA NC_004431.1 1545037 1546740 D Escherichia coli K-12 ortholog: b1243; Escherichia coli O157:H7 ortholog: z2019; periplasmic oligopeptide-binding protein 1545037..1546740 Escherichia coli CFT073 1035489 NP_753613.1 CDS oppB NC_004431.1 1546826 1547746 D Escherichia coli K-12 ortholog: b1244; Escherichia coli O157:H7 ortholog: z2020; oligopeptide transporter permease 1546826..1547746 Escherichia coli CFT073 1035490 NP_753614.1 CDS oppC NC_004431.1 1547761 1548669 D Escherichia coli K-12 ortholog: b1245; Escherichia coli O157:H7 ortholog: z2021; oligopeptide transport system permease oppC 1547761..1548669 Escherichia coli CFT073 1035491 NP_753615.1 CDS oppD NC_004431.1 1548681 1549694 D Escherichia coli K-12 ortholog: b1246; Escherichia coli O157:H7 ortholog: z2022; oligopeptide transporter ATP-binding component 1548681..1549694 Escherichia coli CFT073 1035492 NP_753616.1 CDS oppF NC_004431.1 1549691 1550695 D Escherichia coli K-12 ortholog: b1247; Escherichia coli O157:H7 ortholog: z2023; oligopeptide transport ATP-binding protein oppF 1549691..1550695 Escherichia coli CFT073 1035493 NP_753617.2 CDS yciU NC_004431.1 1550748 1551077 R highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein complement(1550748..1551077) Escherichia coli CFT073 1035494 NP_753618.1 CDS cls NC_004431.1 1551112 1552572 R catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase complement(1551112..1552572) Escherichia coli CFT073 1035495 NP_753619.1 CDS c1714 NC_004431.1 1552604 1552888 D hypothetical protein 1552604..1552888 Escherichia coli CFT073 1035496 NP_753620.1 CDS kch NC_004431.1 1552943 1554214 R Escherichia coli K-12 ortholog: b1250; Escherichia coli O157:H7 ortholog: z2028; voltage-gated potassium channel complement(1552943..1554214) Escherichia coli CFT073 1035497 NP_753621.2 CDS yciI NC_004431.1 1554496 1554792 R unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; hypothetical protein complement(1554496..1554792) Escherichia coli CFT073 1035498 NP_753622.1 CDS tonB NC_004431.1 1554965 1555732 D membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transport protein TonB 1554965..1555732 Escherichia coli CFT073 1035499 NP_753623.1 CDS c1718 NC_004431.1 1555198 1555443 R hypothetical protein complement(1555198..1555443) Escherichia coli CFT073 1035500 NP_753624.1 CDS yciA NC_004431.1 1555772 1556170 R YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins; acyl-CoA thioester hydrolase complement(1555772..1556170) Escherichia coli CFT073 1035501 NP_753625.1 CDS ispZ NC_004431.1 1556275 1556814 R Involved in cell division; probably involved in intracellular septation; intracellular septation protein A complement(1556275..1556814) Escherichia coli CFT073 1035502 NP_753626.1 CDS yciC NC_004431.1 1556844 1557587 R Escherichia coli K-12 ortholog: b1255; Escherichia coli O157:H7 ortholog: z2033; hypothetical protein complement(1556844..1557587) Escherichia coli CFT073 1035503 NP_753627.1 CDS ompW NC_004431.1 1557866 1558582 D receptor for colicin S4; outer membrane protein W 1557866..1558582 Escherichia coli CFT073 1035505 NP_753628.1 CDS yciE NC_004431.1 1558641 1559147 R Escherichia coli K-12 ortholog: b1257; Escherichia coli O157:H7 ortholog: z2555; hypothetical protein complement(1558641..1559147) Escherichia coli CFT073 1035506 NP_753629.1 CDS yciF NC_004431.1 1559193 1559696 R Escherichia coli K-12 ortholog: b1258; Escherichia coli O157:H7 ortholog: z2554; hypothetical protein complement(1559193..1559696) Escherichia coli CFT073 1035507 NP_753630.1 CDS trpA NC_004431.1 1560020 1560826 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1560020..1560826) Escherichia coli CFT073 1035508 NP_753631.1 CDS trpB NC_004431.1 1560826 1562019 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1560826..1562019) Escherichia coli CFT073 1035509 NP_753632.1 CDS trpD NC_004431.1 1563393 1564988 R bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase complement(1563393..1564988) Escherichia coli CFT073 1035512 NP_753633.1 CDS trpE NC_004431.1 1564988 1566550 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1564988..1566550) Escherichia coli CFT073 1035513 NP_753635.1 CDS trpH NC_004431.1 1566824 1567705 D Escherichia coli K-12 ortholog: b1266; Escherichia coli O157:H7 ortholog: z2544; protein trpH 1566824..1567705 Escherichia coli CFT073 1035515 NP_753636.1 CDS yciO NC_004431.1 1567666 1568322 D Escherichia coli K-12 ortholog: b1267; Escherichia coli O157:H7 ortholog: z2543; hypothetical protein 1567666..1568322 Escherichia coli CFT073 1035516 NP_753637.1 CDS yciQ NC_004431.1 1568347 1570239 D Escherichia coli K-12 ortholog: b1268; hypothetical protein 1568347..1570239 Escherichia coli CFT073 1035517 NP_753638.1 CDS yciL NC_004431.1 1570452 1571327 D catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1570452..1571327 Escherichia coli CFT073 1035518 NP_753639.1 CDS btuR NC_004431.1 1571367 1571957 R catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase complement(1571367..1571957) Escherichia coli CFT073 1035519 NP_753640.1 CDS yciK NC_004431.1 1571954 1572712 R Escherichia coli K-12 ortholog: b1271; Escherichia coli O157:H7 ortholog: z2539; short chain dehydrogenase complement(1571954..1572712) Escherichia coli CFT073 1035520 NP_753641.1 CDS sohB NC_004431.1 1572932 1573981 D SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 1572932..1573981 Escherichia coli CFT073 1035521 NP_753642.1 CDS c1738 NC_004431.1 1574161 1574619 D Residues 1 to 152 of 152 are 95.39 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein 1574161..1574619 Escherichia coli CFT073 1035522 NP_753643.1 CDS yciN NC_004431.1 1574728 1574979 R Escherichia coli K-12 ortholog: b1273; Escherichia coli O157:H7 ortholog: z2537; hypothetical protein complement(1574728..1574979) Escherichia coli CFT073 1035523 NP_753644.1 CDS c1740 NC_004431.1 1574972 1575127 D hypothetical protein 1574972..1575127 Escherichia coli CFT073 1035524 NP_753645.1 CDS topA NC_004431.1 1575317 1577956 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1575317..1577956 Escherichia coli CFT073 1035525 NP_753646.1 CDS cysB NC_004431.1 1578166 1579140 D LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1578166..1579140 Escherichia coli CFT073 1035526 NP_753647.1 CDS c1743 NC_004431.1 1579435 1579599 D Escherichia coli O157:H7 ortholog: z2534; hypothetical protein 1579435..1579599 Escherichia coli CFT073 1035527 NP_753648.1 CDS c1744 NC_004431.1 1579581 1579769 D Escherichia coli O157:H7 ortholog: z2533; hypothetical protein 1579581..1579769 Escherichia coli CFT073 1035528 NP_753649.1 CDS acnA NC_004431.1 1580128 1582803 D Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1580128..1582803 Escherichia coli CFT073 1035529 NP_753650.2 CDS ribA NC_004431.1 1582867 1583457 R catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II complement(1582867..1583457) Escherichia coli CFT073 1035530 NP_753651.1 CDS pgpB NC_004431.1 1583627 1584391 D Escherichia coli K-12 ortholog: b1278; Escherichia coli O157:H7 ortholog: z2529; phosphatidylglycerophosphatase B 1583627..1584391 Escherichia coli CFT073 1035531 NP_753652.1 CDS yciS NC_004431.1 1584540 1584848 D Escherichia coli K-12 ortholog: b1279; Escherichia coli O157:H7 ortholog: z2528; hypothetical protein 1584540..1584848 Escherichia coli CFT073 1035532 NP_753653.1 CDS yciM NC_004431.1 1584855 1586024 D Escherichia coli K-12 ortholog: b1280; Escherichia coli O157:H7 ortholog: z2526; tetratricopeptide repeat protein 1584855..1586024 Escherichia coli CFT073 1035533 NP_753654.1 CDS pyrF NC_004431.1 1586064 1586951 D OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1586064..1586951 Escherichia coli CFT073 1035534 NP_753655.1 CDS yciH NC_004431.1 1586948 1587277 D involved in start site selection during the initiation of translation; translation initiation factor Sui1 1586948..1587277 Escherichia coli CFT073 1035535 NP_753656.1 CDS c1752 NC_004431.1 1587301 1587453 D hypothetical protein 1587301..1587453 Escherichia coli CFT073 1035536 NP_753657.1 CDS osmB NC_004431.1 1587403 1587621 R Escherichia coli K-12 ortholog: b1283; Escherichia coli O157:H7 ortholog: z2523; lipoprotein complement(1587403..1587621) Escherichia coli CFT073 1035537 NP_753658.1 CDS yciT NC_004431.1 1587890 1588639 R Escherichia coli K-12 ortholog: b1284; Escherichia coli O157:H7 ortholog: z2521; transcriptional regulator YciT complement(1587890..1588639) Escherichia coli CFT073 1035538 NP_753659.1 CDS c1755 NC_004431.1 1588728 1588901 R Escherichia coli O157:H7 ortholog: z2519; hypothetical protein complement(1588728..1588901) Escherichia coli CFT073 1035539 NP_753660.1 CDS yciR NC_004431.1 1589049 1591034 R c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator complement(1589049..1591034) Escherichia coli CFT073 1035540 NP_753661.1 CDS rnb NC_004431.1 1591268 1593202 R Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II complement(1591268..1593202) Escherichia coli CFT073 1035542 NP_753662.3 CDS yciW NC_004431.1 1593270 1594475 R Escherichia coli K-12 ortholog: b1287; Escherichia coli O157:H7 ortholog: z2513; hypothetical protein complement(1593270..1594475) Escherichia coli CFT073 1035543 NP_753663.1 CDS fabI NC_004431.1 1594542 1595330 R Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase complement(1594542..1595330) Escherichia coli CFT073 1035544 NP_753664.1 CDS c1760 NC_004431.1 1595709 1596374 D Escherichia coli O157:H7 ortholog: z2510; transcriptional repressor 1595709..1596374 Escherichia coli CFT073 1035546 NP_753665.1 CDS c1761 NC_004431.1 1596490 1597644 D Escherichia coli K-12 ortholog: b0463; Escherichia coli O157:H7 ortholog: z2509; acriflavin resistance protein A 1596490..1597644 Escherichia coli CFT073 1035547 NP_753666.1 CDS c1762 NC_004431.1 1597613 1597756 D hypothetical protein 1597613..1597756 Escherichia coli CFT073 1035548 NP_753667.1 CDS c1763 NC_004431.1 1597620 1597748 R hypothetical protein complement(1597620..1597748) Escherichia coli CFT073 1035549 NP_753668.1 CDS c1764 NC_004431.1 1597734 1600751 D Escherichia coli K-12 ortholog: b0462; Escherichia coli O157:H7 ortholog: z2508; acriflavin resistance protein B 1597734..1600751 Escherichia coli CFT073 1035550 NP_753669.1 CDS c1765 NC_004431.1 1600755 1602128 D Escherichia coli O157:H7 ortholog: z2506; hypothetical protein 1600755..1602128 Escherichia coli CFT073 1035551 NP_753670.1 CDS c1766 NC_004431.1 1602137 1603300 D Residues 1 to 387 of 387 are 98.96 pct identical to residues 1 to 387 of 387 from GenPept.129 : >dbj|BAB35289.1| (AP002556) membrane transport protein [Escherichia coli O157:H7]; membrane transporter 1602137..1603300 Escherichia coli CFT073 1035552 NP_753671.1 CDS sapF NC_004431.1 1603348 1604154 R Escherichia coli K-12 ortholog: b1290; Escherichia coli O157:H7 ortholog: z2500; peptide transport system ATP-binding protein sapF complement(1603348..1604154) Escherichia coli CFT073 1035553 NP_753672.1 CDS sapD NC_004431.1 1604156 1605148 R Escherichia coli K-12 ortholog: b1291; Escherichia coli O157:H7 ortholog: z2499; peptide transport system ATP-binding protein sapD complement(1604156..1605148) Escherichia coli CFT073 1035554 NP_753673.1 CDS sapC NC_004431.1 1605148 1606038 R Escherichia coli K-12 ortholog: b1292; Escherichia coli O157:H7 ortholog: z2498; peptide transport system permease sapC complement(1605148..1606038) Escherichia coli CFT073 1035555 NP_753674.1 CDS sapB NC_004431.1 1606025 1606990 R Escherichia coli K-12 ortholog: b1293; Escherichia coli O157:H7 ortholog: z2496; peptide transport system permease sapB complement(1606025..1606990) Escherichia coli CFT073 1035556 NP_753675.1 CDS sapA NC_004431.1 1606987 1608630 R Escherichia coli K-12 ortholog: b1294; Escherichia coli O157:H7 ortholog: z2494; peptide transport periplasmic protein sapA complement(1606987..1608630) Escherichia coli CFT073 1035557 NP_753676.1 CDS ymjA NC_004431.1 1608943 1609188 R Escherichia coli K-12 ortholog: b1295; Escherichia coli O157:H7 ortholog: z2493; hypothetical protein complement(1608943..1609188) Escherichia coli CFT073 1035558 NP_753677.3 CDS pspF NC_004431.1 1609615 1610607 R transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator complement(1609615..1610607) Escherichia coli CFT073 1035559 NP_753678.1 CDS pspA NC_004431.1 1610758 1611426 D involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1610758..1611426 Escherichia coli CFT073 1035560 NP_753679.1 CDS pspB NC_004431.1 1611480 1611704 D acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1611480..1611704 Escherichia coli CFT073 1035561 NP_753680.1 CDS c1776 NC_004431.1 1611499 1611756 R hypothetical protein complement(1611499..1611756) Escherichia coli CFT073 1035562 NP_753681.1 CDS pspC NC_004431.1 1611704 1612063 D with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1611704..1612063 Escherichia coli CFT073 1035563 NP_753682.1 CDS pspD NC_004431.1 1612072 1612293 D Escherichia coli K-12 ortholog: b1307; Escherichia coli O157:H7 ortholog: z2478; peripheral inner membrane phage-shock protein 1612072..1612293 Escherichia coli CFT073 1035564 NP_753683.1 CDS pspE NC_004431.1 1612368 1612682 D rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1612368..1612682 Escherichia coli CFT073 1035565 NP_753684.1 CDS ycjM NC_004431.1 1612869 1614575 D Escherichia coli K-12 ortholog: b1309; Escherichia coli O157:H7 ortholog: z2475; sucrose phosphorylase 1612869..1614575 Escherichia coli CFT073 1035566 NP_753685.1 CDS c1781 NC_004431.1 1614390 1614590 R hypothetical protein complement(1614390..1614590) Escherichia coli CFT073 1035567 NP_753686.1 CDS ycjN NC_004431.1 1614589 1615881 D Escherichia coli K-12 ortholog: b1310; ABC transporter periplasmic-binding protein 1614589..1615881 Escherichia coli CFT073 1035568 NP_753687.1 CDS ycjO NC_004431.1 1615902 1616783 D Escherichia coli K-12 ortholog: b1311; Escherichia coli O157:H7 ortholog: z2472; ABC transporter permease 1615902..1616783 Escherichia coli CFT073 1035569 NP_753688.1 CDS ycjP NC_004431.1 1616770 1617612 D Escherichia coli K-12 ortholog: b1312; Escherichia coli O157:H7 ortholog: z2471; ABC transporter permease 1616770..1617612 Escherichia coli CFT073 1035570 NP_753689.1 CDS ycjQ NC_004431.1 1617643 1618695 D Escherichia coli K-12 ortholog: b1313; Escherichia coli O157:H7 ortholog: z2470; hypothetical protein 1617643..1618695 Escherichia coli CFT073 1035571 NP_753690.1 CDS ycjR NC_004431.1 1618705 1619502 D Escherichia coli K-12 ortholog: b1314; Escherichia coli O157:H7 ortholog: z2469; hypothetical protein 1618705..1619502 Escherichia coli CFT073 1035572 NP_753691.1 CDS ycjS NC_004431.1 1619512 1620567 D Escherichia coli K-12 ortholog: b1315; Escherichia coli O157:H7 ortholog: z2468; oxidoreductase ycjS 1619512..1620567 Escherichia coli CFT073 1035573 NP_753692.1 CDS ycjT NC_004431.1 1620564 1622831 D Escherichia coli K-12 ortholog: b1316; Escherichia coli O157:H7 ortholog: z2467; transport protein YcjT 1620564..1622831 Escherichia coli CFT073 1035574 NP_753693.1 CDS ycjU NC_004431.1 1622828 1623487 D Escherichia coli K-12 ortholog: b1317; Escherichia coli O157:H7 ortholog: z2465; beta-phosphoglucomutase 1622828..1623487 Escherichia coli CFT073 1035575 NP_753694.1 CDS ycjV NC_004431.1 1623501 1624583 D Escherichia coli K-12 ortholog: b1318; Escherichia coli O157:H7 ortholog: z2463; ABC transporter ATP-binding protein 1623501..1624583 Escherichia coli CFT073 1035576 NP_753695.1 CDS ompG NC_004431.1 1624577 1625533 D Escherichia coli K-12 ortholog: b1319; Escherichia coli O157:H7 ortholog: z2462; outer membrane protein G 1624577..1625533 Escherichia coli CFT073 1035577 NP_753696.1 CDS ycjW NC_004431.1 1625584 1626582 R Escherichia coli K-12 ortholog: b1320; Escherichia coli O157:H7 ortholog: z2461; transcriptional regulator YcjW complement(1625584..1626582) Escherichia coli CFT073 1035578 NP_753697.1 CDS ycjX NC_004431.1 1626666 1628135 D Escherichia coli K-12 ortholog: b1321; Escherichia coli O157:H7 ortholog: z2458; hypothetical protein 1626666..1628135 Escherichia coli CFT073 1035579 NP_753698.1 CDS ycjF NC_004431.1 1628132 1629193 D Escherichia coli K-12 ortholog: b1322; Escherichia coli O157:H7 ortholog: z2456; hypothetical protein 1628132..1629193 Escherichia coli CFT073 1035580 NP_753699.1 CDS tyrR NC_004431.1 1629314 1630882 D regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1629314..1630882 Escherichia coli CFT073 1035581 NP_753700.1 CDS tpx NC_004431.1 1630926 1631432 R antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase complement(1630926..1631432) Escherichia coli CFT073 1035582 NP_753701.1 CDS ycjG NC_004431.1 1631509 1632516 D Escherichia coli K-12 ortholog: b1325; Escherichia coli O157:H7 ortholog: z2450; hypothetical protein 1631509..1632516 Escherichia coli CFT073 1035583 NP_753702.1 CDS c1800 NC_004431.1 1633510 1634148 R Escherichia coli O157:H7 ortholog: z2446; hypothetical protein complement(1633510..1634148) Escherichia coli CFT073 1035586 NP_753703.1 CDS c1801 NC_004431.1 1634219 1635151 R Escherichia coli K-12 ortholog: b1327; Escherichia coli O157:H7 ortholog: z2442; hypothetical protein complement(1634219..1635151) Escherichia coli CFT073 1035588 NP_753704.1 CDS c1802 NC_004431.1 1635277 1636176 D Escherichia coli K-12 ortholog: b1328; Escherichia coli O157:H7 ortholog: z2439; transcriptional regulator YcjZ 1635277..1636176 Escherichia coli CFT073 1035589 NP_753705.1 CDS mppA NC_004431.1 1636492 1638126 D Escherichia coli K-12 ortholog: b1329; Escherichia coli O157:H7 ortholog: z2438; periplasmic murein peptide-binding protein 1636492..1638126 Escherichia coli CFT073 1035590 NP_753706.1 CDS ynaI NC_004431.1 1638177 1639208 R Escherichia coli K-12 ortholog: b1330; Escherichia coli O157:H7 ortholog: z2437; hypothetical protein complement(1638177..1639208) Escherichia coli CFT073 1035591 NP_753707.1 CDS ynaJ NC_004431.1 1639452 1639709 D Escherichia coli K-12 ortholog: b1332; Escherichia coli O157:H7 ortholog: z2436; hypothetical protein 1639452..1639709 Escherichia coli CFT073 1035592 NP_753708.1 CDS ydaA NC_004431.1 1639759 1640709 R with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE complement(1639759..1640709) Escherichia coli CFT073 1035593 NP_753709.2 CDS fnr NC_004431.1 1640861 1641613 R Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator complement(1640861..1641613) Escherichia coli CFT073 1035594 NP_753710.1 CDS ogt NC_004431.1 1641808 1642323 R Escherichia coli K-12 ortholog: b1335; Escherichia coli O157:H7 ortholog: z2432; O-6-alkylguanine-DNA:cysteine-protein methyltransferase complement(1641808..1642323) Escherichia coli CFT073 1035598 NP_753711.1 CDS c1809 NC_004431.1 1642334 1642525 R Residues 14 to 63 of 63 are 75.92 pct identical to residues 179 to 230 of 230 from GenPept.129 : >gb|AAG56464.1|AE005372_9 (AE005372) partial pump protein; disrupted by IS629 [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(1642334..1642525) Escherichia coli CFT073 1035599 NP_753712.1 CDS c1810 NC_004431.1 1642836 1643651 R Residues 10 to 258 of 271 are 35.34 pct identical to residues 18 to 260 of 268 from GenPept.129 : >emb|CAD16771.1| (AL646073) PROBABLE TRANSCRIPTION REGULATOR PROTEIN [Ralstonia solanacearum]; hypothetical protein complement(1642836..1643651) Escherichia coli CFT073 1035600 NP_753713.1 CDS c1811 NC_004431.1 1643745 1644053 D Residues 14 to 89 of 102 are 51.31 pct identical to residues 37 to 111 of 367 from GenPept.129 : >dbj|BAB49683.1| (AP003000) probable secretion protein [Mesorhizobium loti]; hypothetical protein 1643745..1644053 Escherichia coli CFT073 1035602 NP_753714.1 CDS c1812 NC_004431.1 1644038 1644436 D Residues 1 to 126 of 132 are 46.03 pct identical to residues 378 to 503 of 518 from GenPept.129 : >dbj|BAB49682.1| (AP003000) probable transporter [Mesorhizobium loti]; hypothetical protein 1644038..1644436 Escherichia coli CFT073 1035603 NP_753715.1 CDS c1813 NC_004431.1 1644184 1644312 R hypothetical protein complement(1644184..1644312) Escherichia coli CFT073 1035612 NP_753716.1 CDS ydaL NC_004431.1 1644631 1645194 D Escherichia coli K-12 ortholog: b1340; Escherichia coli O157:H7 ortholog: z2422; hypothetical protein 1644631..1645194 Escherichia coli CFT073 1035614 NP_753717.1 CDS ydaM NC_004431.1 1645215 1646507 R Escherichia coli K-12 ortholog: b1341; Escherichia coli O157:H7 ortholog: z2421; hypothetical protein complement(1645215..1646507) Escherichia coli CFT073 1035615 NP_753718.1 CDS zntB NC_004431.1 1646702 1647685 D Escherichia coli K-12 ortholog: b1342; Escherichia coli O157:H7 ortholog: z2419; zinc transporter 1646702..1647685 Escherichia coli CFT073 1035618 NP_753719.1 CDS dbpA NC_004431.1 1648163 1649536 D exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1648163..1649536 Escherichia coli CFT073 1035619 NP_753720.1 CDS ydaO NC_004431.1 1649665 1650600 R TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase complement(1649665..1650600) Escherichia coli CFT073 1035620 NP_753721.1 CDS c1819 NC_004431.1 1650652 1650960 R Residues 27 to 102 of 102 are 98.68 pct identical to residues 336 to 411 of 411 from MG1655 : b1345; hypothetical protein complement(1650652..1650960) Escherichia coli CFT073 1035621 NP_753722.1 CDS c1820 NC_004431.1 1652469 1652837 R Residues 4 to 90 of 122 are 72.41 pct identical to residues 18 to 104 of 282 from GenPept.129 : >gb|AAL21744.1| (AE008830) Salmonella iron transporter: fur regulated [Salmonella typhimurium LT2]; hypothetical protein complement(1652469..1652837) Escherichia coli CFT073 1035623 NP_753723.1 CDS ynaF NC_004431.1 1652926 1653432 R Escherichia coli K-12 ortholog: b1376; Escherichia coli O157:H7 ortholog: z2335; hypothetical protein complement(1652926..1653432) Escherichia coli CFT073 1035624 NP_753724.1 CDS ompN NC_004431.1 1653501 1654634 R Porin ompN; Escherichia coli K-12 ortholog: b1377; Escherichia coli O157:H7 ortholog: z2334; outer membrane protein N complement(1653501..1654634) Escherichia coli CFT073 1035625 NP_753725.1 CDS ydbK NC_004431.1 1655000 1658524 R Escherichia coli K-12 ortholog: b1378; Escherichia coli O157:H7 ortholog: z2332; pyruvate-flavodoxin oxidoreductase complement(1655000..1658524) Escherichia coli CFT073 1035626 NP_753726.1 CDS c1824 NC_004431.1 1658595 1658930 R Residues 18 to 85 of 111 are 52.94 pct identical to residues 2 to 69 of 99 from GenPept.129 : >gb|AAL20568.1| (AE008773) reverse transcriptase [Salmonella typhimurium LT2]; hypothetical protein complement(1658595..1658930) Escherichia coli CFT073 1035627 NP_753727.1 CDS c1825 NC_004431.1 1658909 1659064 D Residues 1 to 51 of 51 are 100.00 pct identical to residues 1 to 51 of 51 from GenPept.129 : >dbj|BAA14988.1| (D90776) ORF_ID:o264#6; similar to [SwissProt Accession Number P52646] [Escherichia coli]; hypothetical protein 1658909..1659064 Escherichia coli CFT073 1035628 NP_753728.1 CDS hslJ NC_004431.1 1659061 1659495 R Escherichia coli K-12 ortholog: b1379; Escherichia coli O157:H7 ortholog: z2330; heat-inducible protein complement(1659061..1659495) Escherichia coli CFT073 1035629 NP_753729.1 CDS ldhA NC_004431.1 1659594 1660583 R Catalyzes the reduction of sulfopyruvate to (R)-sulfolactate much more efficiently than the reverse reaction. Also catalyzes the reduction of oxaloacetate, alpha-ketoglutarate, and to a much lower extent, KHTCA, but not pyruvate. Involved in the biosynthes; D-lactate dehydrogenase complement(1659594..1660583) Escherichia coli CFT073 1035630 NP_753730.1 CDS ydbH NC_004431.1 1660791 1663430 D Escherichia coli K-12 ortholog: b1381; Escherichia coli O157:H7 ortholog: z2328; hypothetical protein 1660791..1663430 Escherichia coli CFT073 1035631 NP_753731.1 CDS ynbE NC_004431.1 1663427 1663612 D Escherichia coli K-12 ortholog: b1382; Escherichia coli O157:H7 ortholog: z2327; hypothetical protein 1663427..1663612 Escherichia coli CFT073 1035632 NP_753732.1 CDS ydbL NC_004431.1 1663587 1663946 D Escherichia coli K-12 ortholog: b1383; Escherichia coli O157:H7 ortholog: z2326; hypothetical protein 1663587..1663946 Escherichia coli CFT073 1035633 NP_753733.1 CDS ydbC NC_004431.1 1670579 1671439 D Escherichia coli K-12 ortholog: b1406; Escherichia coli O157:H7 ortholog: z2321; oxidoreductase 1670579..1671439 Escherichia coli CFT073 1035636 NP_753734.1 CDS c1833 NC_004431.1 1671484 1671708 R hypothetical protein complement(1671484..1671708) Escherichia coli CFT073 1035637 NP_753735.1 CDS ynbA NC_004431.1 1671738 1672343 D Escherichia coli K-12 ortholog: b1408; Escherichia coli O157:H7 ortholog: z2319; hypothetical protein 1671738..1672343 Escherichia coli CFT073 1035639 NP_753736.1 CDS ynbB NC_004431.1 1672343 1673239 D Escherichia coli K-12 ortholog: b1409; Escherichia coli O157:H7 ortholog: z2318; hypothetical protein 1672343..1673239 Escherichia coli CFT073 1035640 NP_753737.1 CDS ynbC NC_004431.1 1673255 1675012 D Escherichia coli K-12 ortholog: b1410; Escherichia coli O157:H7 ortholog: z2317; hypothetical protein 1673255..1675012 Escherichia coli CFT073 1035641 NP_753738.1 CDS ynbD NC_004431.1 1674927 1676318 D Escherichia coli K-12 ortholog: b1411; Escherichia coli O157:H7 ortholog: z2316; hypothetical protein 1674927..1676318 Escherichia coli CFT073 1035642 NP_753739.1 CDS c1838 NC_004431.1 1676303 1676965 D hypothetical protein 1676303..1676965 Escherichia coli CFT073 1035643 NP_753740.1 CDS acpD NC_004431.1 1676372 1676977 R FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase complement(1676372..1676977) Escherichia coli CFT073 1035644 NP_753741.2 CDS hrpA NC_004431.1 1677235 1681080 D involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1677235..1681080 Escherichia coli CFT073 1035645 NP_753742.1 CDS ydcF NC_004431.1 1681353 1682153 D Escherichia coli K-12 ortholog: b1414; Escherichia coli O157:H7 ortholog: z2308; hypothetical protein 1681353..1682153 Escherichia coli CFT073 1035647 NP_753743.1 CDS aldA NC_004431.1 1682350 1683789 D NAD-linked; aldehyde dehydrogenase 1682350..1683789 Escherichia coli CFT073 1035648 NP_753744.1 CDS c1843 NC_004431.1 1683831 1684832 R Escherichia coli K-12 ortholog: b1779; Escherichia coli O157:H7 ortholog: z2304; glyceraldehyde 3-phosphate dehydrogenase A complement(1683831..1684832) Escherichia coli CFT073 1035649 NP_753745.2 CDS cybB NC_004431.1 1685021 1685551 D B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1685021..1685551 Escherichia coli CFT073 1035650 NP_753746.1 CDS ydcA NC_004431.1 1685796 1685969 D Escherichia coli K-12 ortholog: b1419; Escherichia coli O157:H7 ortholog: z2302; hypothetical protein 1685796..1685969 Escherichia coli CFT073 1035654 NP_753747.1 CDS c1846 NC_004431.1 1686126 1686596 D Residues 10 to 156 of 156 are 95.91 pct identical to residues 400 to 546 of 546 from MG1655 : b1421; hypothetical protein 1686126..1686596 Escherichia coli CFT073 1035656 NP_753748.1 CDS ycdI NC_004431.1 1686634 1687698 R Escherichia coli K-12 ortholog: b1422; Escherichia coli O157:H7 ortholog: z2299; transcriptional regulator YdcI complement(1686634..1687698) Escherichia coli CFT073 1035658 NP_753749.1 CDS ydcJ NC_004431.1 1687774 1689117 D Escherichia coli K-12 ortholog: b1423; hypothetical protein 1687774..1689117 Escherichia coli CFT073 1035659 NP_753750.1 CDS mdoD NC_004431.1 1689342 1690997 D involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1689342..1690997 Escherichia coli CFT073 1035660 NP_753751.1 CDS ydcH NC_004431.1 1691131 1691361 D Escherichia coli K-12 ortholog: b1426; Escherichia coli O157:H7 ortholog: z2292; hypothetical protein 1691131..1691361 Escherichia coli CFT073 1035661 NP_753752.1 CDS rimL NC_004431.1 1691409 1691963 D Escherichia coli K-12 ortholog: b1427; ribosomal-protein-L7/L12-serine acetyltransferase 1691409..1691963 Escherichia coli CFT073 1035663 NP_753753.1 CDS ydcK NC_004431.1 1691955 1692935 R Escherichia coli K-12 ortholog: b1428; Escherichia coli O157:H7 ortholog: z2290; hypothetical protein complement(1691955..1692935) Escherichia coli CFT073 1035665 NP_753754.1 CDS tehA NC_004431.1 1692951 1694051 D Escherichia coli K-12 ortholog: b1429; Escherichia coli O157:H7 ortholog: z2289; potassium-tellurite ethidium and proflavin transporter 1692951..1694051 Escherichia coli CFT073 1035674 NP_753755.1 CDS tehB NC_004431.1 1694048 1694641 D with TehA confers resistance to tellurite; tellurite resistance protein TehB 1694048..1694641 Escherichia coli CFT073 1035675 NP_753756.1 CDS c1855 NC_004431.1 1694925 1695053 R hypothetical protein complement(1694925..1695053) Escherichia coli CFT073 1035676 NP_753757.1 CDS ydcL NC_004431.1 1694944 1695612 D Escherichia coli K-12 ortholog: b1431; Escherichia coli O157:H7 ortholog: z2287; lipoprotein ydcL 1694944..1695612 Escherichia coli CFT073 1035680 NP_753758.1 CDS ydcO NC_004431.1 1695647 1696942 R Escherichia coli K-12 ortholog: b1433; Escherichia coli O157:H7 ortholog: z2286; hypothetical protein complement(1695647..1696942) Escherichia coli CFT073 1035681 NP_753759.1 CDS ydcN NC_004431.1 1696911 1697447 D Escherichia coli K-12 ortholog: b1434; Escherichia coli O157:H7 ortholog: z2285; hypothetical protein 1696911..1697447 Escherichia coli CFT073 1035682 NP_753760.1 CDS ydcP NC_004431.1 1697478 1699481 D Escherichia coli K-12 ortholog: b1435; Escherichia coli O157:H7 ortholog: z2284; protease ydcP 1697478..1699481 Escherichia coli CFT073 1035683 NP_753761.1 CDS yncJ NC_004431.1 1699573 1699803 R Escherichia coli K-12 ortholog: b1436; Escherichia coli O157:H7 ortholog: z2283; hypothetical protein complement(1699573..1699803) Escherichia coli CFT073 1035684 NP_753762.1 CDS c1861 NC_004431.1 1699860 1699988 R hypothetical protein complement(1699860..1699988) Escherichia coli CFT073 1035685 NP_753763.1 CDS c1862 NC_004431.1 1700015 1700218 D Residues 1 to 67 of 67 are 95.52 pct identical to residues 79 to 145 of 145 from GenPept.129 : >gb|AAC74520.1| (AE000241) orf, hypothetical protein [Escherichia coli K12]; hypothetical protein 1700015..1700218 Escherichia coli CFT073 1035686 NP_753764.1 CDS ydcR NC_004431.1 1700297 1701703 D Escherichia coli K-12 ortholog: b1439; Escherichia coli O157:H7 ortholog: z2280; hypothetical protein 1700297..1701703 Escherichia coli CFT073 1035688 NP_753765.1 CDS ydcS NC_004431.1 1701948 1703093 D Escherichia coli K-12 ortholog: b1440; Escherichia coli O157:H7 ortholog: z2279; ABC transporter periplasmic-binding protein 1701948..1703093 Escherichia coli CFT073 1035689 NP_753766.1 CDS ydcT NC_004431.1 1703111 1704124 D Escherichia coli K-12 ortholog: b1441; Escherichia coli O157:H7 ortholog: z2278; ABC transporter ATP-binding protein 1703111..1704124 Escherichia coli CFT073 1035690 NP_753767.1 CDS ydcU NC_004431.1 1704125 1705066 D Escherichia coli K-12 ortholog: b1442; Escherichia coli O157:H7 ortholog: z2277; ABC transporter permease 1704125..1705066 Escherichia coli CFT073 1035691 NP_753768.1 CDS ydcV NC_004431.1 1705056 1705700 D Escherichia coli K-12 ortholog: b1443; Escherichia coli O157:H7 ortholog: z2276; ABC transporter permease 1705056..1705700 Escherichia coli CFT073 1035693 NP_753769.1 CDS ydcW NC_004431.1 1705873 1707297 D catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1705873..1707297 Escherichia coli CFT073 1035695 NP_753770.1 CDS c1870 NC_004431.1 1707609 1707857 D Escherichia coli K-12 ortholog: b1445; Escherichia coli O157:H7 ortholog: z2274; hypothetical protein 1707609..1707857 Escherichia coli CFT073 1035696 NP_753771.1 CDS ydc NC_004431.1 1707943 1708176 D Escherichia coli K-12 ortholog: b1446; Escherichia coli O157:H7 ortholog: z2273; hypothetical protein 1707943..1708176 Escherichia coli CFT073 1035697 NP_753772.1 CDS ydcZ NC_004431.1 1708177 1708626 R Escherichia coli K-12 ortholog: b1447; Escherichia coli O157:H7 ortholog: z2272; hypothetical protein complement(1708177..1708626) Escherichia coli CFT073 1035698 NP_753773.1 CDS yncA NC_004431.1 1708623 1709204 R Escherichia coli K-12 ortholog: b1448; Escherichia coli O157:H7 ortholog: z2271; acetyltransferase yncA complement(1708623..1709204) Escherichia coli CFT073 1035699 NP_753774.1 CDS c1874 NC_004431.1 1709348 1709584 D Residues 11 to 66 of 78 are 89.28 pct identical to residues 71 to 126 of 240 from MG1655 : b1450; hypothetical protein 1709348..1709584 Escherichia coli CFT073 1035700 NP_753775.1 CDS yncE NC_004431.1 1711967 1713028 D Escherichia coli K-12 ortholog: b1452; Escherichia coli O157:H7 ortholog: z2267; hypothetical protein 1711967..1713028 Escherichia coli CFT073 1035703 NP_753776.1 CDS ansP NC_004431.1 1713141 1714691 R L-asparagine transport protein; Escherichia coli K-12 ortholog: b1453; Escherichia coli O157:H7 ortholog: z2266; L-asparagine permease complement(1713141..1714691) Escherichia coli CFT073 1035705 NP_753777.1 CDS c1879 NC_004431.1 1714907 1715083 D Residues 1 to 58 of 58 are 96.55 pct identical to residues 1 to 58 of 205 from GenPept.129 : >gb|AAG56321.1|AE005361_2 (AE005361) transferase [Escherichia coli O157:H7 EDL933]; hypothetical protein 1714907..1715083 Escherichia coli CFT073 1035706 NP_753778.1 CDS c1880 NC_004431.1 1715196 1715525 D Residues 1 to 109 of 109 are 90.82 pct identical to residues 97 to 205 of 205 from MG1655 : b1454; hypothetical protein 1715196..1715525 Escherichia coli CFT073 1035708 NP_753779.1 CDS c1881 NC_004431.1 1715945 1716094 R hypothetical protein complement(1715945..1716094) Escherichia coli CFT073 1035713 NP_753780.1 CDS c1882 NC_004431.1 1716066 1716350 D Residues 11 to 94 of 94 are 67.85 pct identical to residues 11 to 94 of 94 from GenPept.129 : >gb|AAF96019.1| (AE004353) conserved hypothetical protein [Vibrio cholerae]; hypothetical protein 1716066..1716350 Escherichia coli CFT073 1035719 NP_753781.1 CDS c1883 NC_004431.1 1716369 1718327 D Escherichia coli O157:H7 ortholog: z0707; hypothetical protein 1716369..1718327 Escherichia coli CFT073 1035722 NP_753782.1 CDS c1884 NC_004431.1 1718427 1719167 D hypothetical protein 1718427..1719167 Escherichia coli CFT073 1035724 NP_753783.1 CDS c1885 NC_004431.1 1719505 1720740 D hypothetical protein 1719505..1720740 Escherichia coli CFT073 1035729 NP_753784.1 CDS c1886 NC_004431.1 1720751 1721794 D hypothetical protein 1720751..1721794 Escherichia coli CFT073 1035730 NP_753785.1 CDS c1887 NC_004431.1 1721906 1722190 D Residues 11 to 94 of 94 are 66.66 pct identical to residues 11 to 94 of 94 from GenPept.129 : >gb|AAF96019.1| (AE004353) conserved hypothetical protein [Vibrio cholerae]; hypothetical protein 1721906..1722190 Escherichia coli CFT073 1035731 NP_753786.1 CDS c1888 NC_004431.1 1722209 1724614 D Escherichia coli O157:H7 ortholog: z0267; hypothetical protein 1722209..1724614 Escherichia coli CFT073 1035735 NP_753787.1 CDS c1889 NC_004431.1 1724601 1725203 D hypothetical protein 1724601..1725203 Escherichia coli CFT073 1035747 NP_753788.1 CDS c1890 NC_004431.1 1725540 1725992 D hypothetical protein 1725540..1725992 Escherichia coli CFT073 1035748 NP_753789.1 CDS c1891 NC_004431.1 1726211 1726717 D hypothetical protein 1726211..1726717 Escherichia coli CFT073 1035772 NP_753790.1 CDS c1892 NC_004431.1 1726714 1727181 D hypothetical protein 1726714..1727181 Escherichia coli CFT073 1035775 NP_753791.1 CDS c1893 NC_004431.1 1727294 1727437 D Residues 1 to 47 of 47 are 87.23 pct identical to residues 68 to 114 of 203 from GenPept.129 : >gb|AAG56311.1|AE005360_3 (AE005360) H repeat-associated protein of Rhs element [Escherichia coli O157:H7 EDL933]; hypothetical protein 1727294..1727437 Escherichia coli CFT073 1035790 NP_753792.1 CDS yddH NC_004431.1 1728047 1728616 R Escherichia coli K-12 ortholog: b1462; Escherichia coli O157:H7 ortholog: z2251; hypothetical protein complement(1728047..1728616) Escherichia coli CFT073 1035791 NP_753793.1 CDS nhoA NC_004431.1 1728791 1729636 D Escherichia coli K-12 ortholog: b1463; Escherichia coli O157:H7 ortholog: z2250; N-hydroxyarylamine O-acetyltransferase 1728791..1729636 Escherichia coli CFT073 1035792 NP_753794.1 CDS yddE NC_004431.1 1729732 1730625 R ORFB; Escherichia coli K-12 ortholog: b1464; Escherichia coli O157:H7 ortholog: z2248; hypothetical protein complement(1729732..1730625) Escherichia coli CFT073 1035794 NP_753795.1 CDS narV NC_004431.1 1730705 1731385 R Escherichia coli K-12 ortholog: b1465; Escherichia coli O157:H7 ortholog: z2247; respiratory nitrate reductase 2 subunit gamma complement(1730705..1731385) Escherichia coli CFT073 1035796 NP_753796.1 CDS narW NC_004431.1 1731382 1732077 R Escherichia coli K-12 ortholog: b1466; Escherichia coli O157:H7 ortholog: z2246; respiratory nitrate reductase 2 subunit delta complement(1731382..1732077) Escherichia coli CFT073 1035798 NP_753797.1 CDS narY NC_004431.1 1732077 1733621 R Escherichia coli K-12 ortholog: b1467; Escherichia coli O157:H7 ortholog: z2245; respiratory nitrate reductase 2 subunit beta complement(1732077..1733621) Escherichia coli CFT073 1035799 NP_753798.1 CDS narZ NC_004431.1 1733618 1737481 R Escherichia coli K-12 ortholog: b1468; Escherichia coli O157:H7 ortholog: z2244; respiratory nitrate reductase 2 subunit alpha complement(1733618..1737481) Escherichia coli CFT073 1035800 NP_753799.1 CDS narU NC_004431.1 1737453 1738841 R Nitrite facilitator 2; Escherichia coli K-12 ortholog: b1469; Escherichia coli O157:H7 ortholog: z2243; nitrite extrusion protein 2 complement(1737453..1738841) Escherichia coli CFT073 1035801 NP_753800.1 CDS yddG NC_004431.1 1739114 1739995 R Escherichia coli K-12 ortholog: b1473; Escherichia coli O157:H7 ortholog: z2238; hypothetical protein complement(1739114..1739995) Escherichia coli CFT073 1035805 NP_753801.1 CDS fdnG NC_004431.1 1740228 1743275 D Escherichia coli K-12 ortholog: b1474; Escherichia coli O157:H7 ortholog: z2236; formate dehydrogenase, nitrate-inducible, major subunit 1740228..1743275 Escherichia coli CFT073 1035806 NP_753802.1 CDS c1905 NC_004431.1 1743252 1744196 R hypothetical protein complement(1743252..1744196) Escherichia coli CFT073 1035807 NP_753803.1 CDS fdnH NC_004431.1 1743288 1744172 D Nitrate-inducible; Iron-sulfur subunit; Escherichia coli K-12 ortholog: b1475; Escherichia coli O157:H7 ortholog: z2235; formate dehydrogenase-N beta subunit 1743288..1744172 Escherichia coli CFT073 1035808 NP_753804.1 CDS fdnI NC_004431.1 1744165 1744818 D nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1744165..1744818 Escherichia coli CFT073 1035811 NP_753805.1 CDS c1908 NC_004431.1 1745018 1745290 D hypothetical protein 1745018..1745290 Escherichia coli CFT073 1035812 NP_753806.1 CDS yddM NC_004431.1 1745044 1745328 R Escherichia coli K-12 ortholog: b1477; Escherichia coli O157:H7 ortholog: z2233; hypothetical protein complement(1745044..1745328) Escherichia coli CFT073 1035813 NP_753807.1 CDS c1910 NC_004431.1 1745328 1745600 R Residues 2 to 90 of 90 are 56.17 pct identical to residues 4 to 92 of 92 from GenPept.129 : >gb|AAC43982.1| (U43847) killer protein [Plasmid Rts1]; hypothetical protein complement(1745328..1745600) Escherichia coli CFT073 1035815 NP_753808.2 CDS adhP NC_004431.1 1745792 1746802 R similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase complement(1745792..1746802) Escherichia coli CFT073 1035817 NP_753809.2 CDS sfcA NC_004431.1 1746936 1748633 R malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase complement(1746936..1748633) Escherichia coli CFT073 1035818 NP_753810.1 CDS rpsV NC_004431.1 1748790 1748927 R protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase; 30S ribosomal subunit S22 complement(1748790..1748927) Escherichia coli CFT073 1035819 NP_753811.2 CDS c1914 NC_004431.1 1749029 1749244 R Biofilm-dependent modulation protein; Escherichia coli K-12 ortholog: b1481; Escherichia coli O157:H7 ortholog: z2229; biofilm-dependent modulation protein complement(1749029..1749244) Escherichia coli CFT073 1035821 NP_753812.1 CDS c1915 NC_004431.1 1749411 1749551 D hypothetical protein 1749411..1749551 Escherichia coli CFT073 1035823 NP_753813.1 CDS osmC NC_004431.1 1749589 1750020 D Escherichia coli K-12 ortholog: b1482; Escherichia coli O157:H7 ortholog: z2228; osmotically inducible protein C 1749589..1750020 Escherichia coli CFT073 1035827 NP_753814.1 CDS c1918 NC_004431.1 1751294 1752634 R Escherichia coli O157:H7 ortholog: z2220; sensor kinase complement(1751294..1752634) Escherichia coli CFT073 1035829 NP_753815.1 CDS c1919 NC_004431.1 1752635 1752853 R Residues 19 to 72 of 72 are 98.14 pct identical to residues 407 to 460 of 460 from MG1655 : b1490; hypothetical protein complement(1752635..1752853) Escherichia coli CFT073 1035831 NP_753816.1 CDS yddW NC_004431.1 1753177 1754496 R Escherichia coli K-12 ortholog: b1491; Escherichia coli O157:H7 ortholog: z2217; lipoprotein yddW complement(1753177..1754496) Escherichia coli CFT073 1035836 NP_753817.1 CDS xasA NC_004431.1 1754627 1756162 R Extreme acid sensitivity protein; Escherichia coli K-12 ortholog: b1492; Escherichia coli O157:H7 ortholog: z2216; amino acid antiporter complement(1754627..1756162) Escherichia coli CFT073 1035837 NP_753818.1 CDS gadB NC_004431.1 1756318 1757787 R Escherichia coli K-12 ortholog: b1493; Escherichia coli O157:H7 ortholog: z2215; glutamate decarboxylase beta complement(1756318..1757787) Escherichia coli CFT073 1035839 NP_753819.1 CDS pqqL NC_004431.1 1758079 1760874 R Escherichia coli K-12 ortholog: b1494; Escherichia coli O157:H7 ortholog: z2214; zinc protease pqqL complement(1758079..1760874) Escherichia coli CFT073 1035840 NP_753820.1 CDS yddB NC_004431.1 1760919 1763291 R CDS103; Escherichia coli K-12 ortholog: b1495; Escherichia coli O157:H7 ortholog: z2213; hypothetical protein complement(1760919..1763291) Escherichia coli CFT073 1035841 NP_753821.1 CDS yddA NC_004431.1 1763329 1765014 R CDS102; Escherichia coli K-12 ortholog: b1496; Escherichia coli O157:H7 ortholog: z2212; ABC transporter ATP-binding protein complement(1763329..1765014) Escherichia coli CFT073 1035844 NP_753822.1 CDS ydeM NC_004431.1 1765305 1766477 R Escherichia coli K-12 ortholog: b1497; Escherichia coli O157:H7 ortholog: z2211; hypothetical protein complement(1765305..1766477) Escherichia coli CFT073 1035845 NP_753823.1 CDS ydeN NC_004431.1 1766514 1768229 R Escherichia coli K-12 ortholog: b1498; Escherichia coli O157:H7 ortholog: z2210; sulfatase ydeN complement(1766514..1768229) Escherichia coli CFT073 1035847 NP_753824.1 CDS ydeO NC_004431.1 1768598 1769359 R regulates the cellular response to acid resistance; transcriptional regulator YdeO complement(1768598..1769359) Escherichia coli CFT073 1035848 NP_753825.1 CDS c1929 NC_004431.1 1769435 1769632 R Escherichia coli K-12 ortholog: b1500; Escherichia coli O157:H7 ortholog: z2208; hypothetical protein complement(1769435..1769632) Escherichia coli CFT073 1035849 NP_753826.1 CDS ydeP NC_004431.1 1769880 1772159 R in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family; oxidoreductase complement(1769880..1772159) Escherichia coli CFT073 1035851 NP_753827.1 CDS ydeQ NC_004431.1 1772498 1773412 R Escherichia coli K-12 ortholog: b1502; Escherichia coli O157:H7 ortholog: z2206; fimbrial-like protein ydeQ complement(1772498..1773412) Escherichia coli CFT073 1035852 NP_753828.1 CDS ydeR NC_004431.1 1773472 1773975 R Escherichia coli K-12 ortholog: b1503; Escherichia coli O157:H7 ortholog: z2205; fimbrial-like protein ydeR complement(1773472..1773975) Escherichia coli CFT073 1035853 NP_753829.1 CDS ydeS NC_004431.1 1773988 1774518 R Escherichia coli K-12 ortholog: b1504; Escherichia coli O157:H7 ortholog: z2204; fimbrial-like protein ydeS complement(1773988..1774518) Escherichia coli CFT073 1035854 NP_753830.1 CDS c1934 NC_004431.1 1774532 1777183 R Escherichia coli K-12 ortholog: b4317; Escherichia coli O157:H7 ortholog: z2203; outer membrane usher protein fimD complement(1774532..1777183) Escherichia coli CFT073 1035855 NP_753831.1 CDS c1935 NC_004431.1 1777225 1777935 R Escherichia coli K-12 ortholog: b4316; Escherichia coli O157:H7 ortholog: z2201; chaperone protein fimC complement(1777225..1777935) Escherichia coli CFT073 1035856 NP_753832.1 CDS c1936 NC_004431.1 1778297 1778908 R Type-1A pilin; Escherichia coli K-12 ortholog: b4314; Escherichia coli O157:H7 ortholog: z2200; Type-1 fimbrial protein, A chain complement(1778297..1778908) Escherichia coli CFT073 1035857 NP_753833.1 CDS c1937 NC_004431.1 1779636 1780418 R Residues 1 to 222 of 260 are 34.22 pct identical to residues 1 to 219 of 219 from GenPept.129 : >dbj|BAA18102.1| (D90911) ORF_ID:sll1218; hypothetical protein [Synechocystis sp. PCC 6803]; hypothetical protein complement(1779636..1780418) Escherichia coli CFT073 1035858 NP_753834.1 CDS oprR NC_004431.1 1780528 1781475 D Escherichia coli K-12 ortholog: b1328; Escherichia coli O157:H7 ortholog: z2439; transcriptional regulator YcjZ 1780528..1781475 Escherichia coli CFT073 1035859 NP_753835.1 CDS c1939 NC_004431.1 1781157 1781609 D Residues 1 to 134 of 150 are 81.34 pct identical to residues 139 to 272 of 363 from GenPept.129 : >emb|CAC90815.1| (AJ414151) conserved hypothetical protein [Yersinia pestis]; hypothetical protein 1781157..1781609 Escherichia coli CFT073 1035860 NP_753836.1 CDS hipA NC_004431.1 1781779 1783197 R Escherichia coli K-12 ortholog: b1507; Escherichia coli O157:H7 ortholog: z2197; protein hipA complement(1781779..1783197) Escherichia coli CFT073 1035862 NP_753837.1 CDS hipB NC_004431.1 1783191 1783475 R Escherichia coli K-12 ortholog: b1508; DNA-binding transcriptional regulator HipB complement(1783191..1783475) Escherichia coli CFT073 1035865 NP_753838.1 CDS tam NC_004431.1 1783765 1784523 D catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 1783765..1784523 Escherichia coli CFT073 1035868 NP_753839.1 CDS yneE NC_004431.1 1784527 1785492 R Escherichia coli K-12 ortholog: b1520; Escherichia coli O157:H7 ortholog: z2185; hypothetical protein complement(1784527..1785492) Escherichia coli CFT073 1035869 NP_753840.1 CDS yneF NC_004431.1 1787317 1788735 R Escherichia coli K-12 ortholog: b1522; Escherichia coli O157:H7 ortholog: z2182; hypothetical protein complement(1787317..1788735) Escherichia coli CFT073 1035871 NP_753841.1 CDS yneG NC_004431.1 1788874 1789233 R Escherichia coli K-12 ortholog: b1523; Escherichia coli O157:H7 ortholog: z2180; hypothetical protein complement(1788874..1789233) Escherichia coli CFT073 1035872 NP_753842.1 CDS yneH NC_004431.1 1789233 1790159 R catalyzes the formation of glutamate from glutamine; glutaminase complement(1789233..1790159) Escherichia coli CFT073 1035873 NP_753843.1 CDS yneI NC_004431.1 1790223 1791635 R in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; succinate semialdehyde dehydrogenase complement(1790223..1791635) Escherichia coli CFT073 1035874 NP_753844.1 CDS yneJ NC_004431.1 1791712 1792593 D Escherichia coli K-12 ortholog: b1526; Escherichia coli O157:H7 ortholog: z2177; transcriptional regulator YneJ 1791712..1792593 Escherichia coli CFT073 1035878 NP_753845.1 CDS sotB NC_004431.1 1792932 1794122 D Escherichia coli K-12 ortholog: b1528; Escherichia coli O157:H7 ortholog: z2173; sugar efflux transporter 1792932..1794122 Escherichia coli CFT073 1035879 NP_753846.1 CDS marC NC_004431.1 1794147 1794812 R protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC complement(1794147..1794812) Escherichia coli CFT073 1035884 NP_753847.1 CDS marR NC_004431.1 1795024 1795458 D Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 1795024..1795458 Escherichia coli CFT073 1035885 NP_753848.2 CDS marA NC_004431.1 1795479 1795862 D transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 1795479..1795862 Escherichia coli CFT073 1035887 NP_753849.1 CDS marB NC_004431.1 1795894 1796112 D Escherichia coli K-12 ortholog: b1532; Escherichia coli O157:H7 ortholog: z2169; hypothetical protein 1795894..1796112 Escherichia coli CFT073 1035888 NP_753850.1 CDS celA NC_004431.1 1796169 1797614 R converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism; 6-phospho-beta-glucosidase complement(1796169..1797614) Escherichia coli CFT073 1035889 NP_753851.1 CDS c1956 NC_004431.1 1797633 1799306 R Escherichia coli K-12 ortholog: b3720; hypothetical protein complement(1797633..1799306) Escherichia coli CFT073 1035894 NP_753852.1 CDS c1957 NC_004431.1 1799361 1799675 R EIIA-Cel; Escherichia coli K-12 ortholog: b1736; Escherichia coli O157:H7 ortholog: z2766; PTS system, cellobiose-specific IIA component complement(1799361..1799675) Escherichia coli CFT073 1035897 NP_753853.1 CDS c1958 NC_004431.1 1799700 1801061 R Residues 17 to 448 of 453 are 36.79 pct identical to residues 1 to 435 of 452 from MG1655 : b1737; hypothetical protein complement(1799700..1801061) Escherichia coli CFT073 1035898 NP_753854.1 CDS c1959 NC_004431.1 1801137 1801448 R EIIB-Cel; Escherichia coli K-12 ortholog: b1738; Escherichia coli O157:H7 ortholog: z2768; PTS system, cellobiose-specific IIB component complement(1801137..1801448) Escherichia coli CFT073 1035900 NP_753855.1 CDS c1960 NC_004431.1 1801647 1802345 D Residues 1 to 232 of 232 are 35.77 pct identical to residues 1 to 232 of 238 from MG1655 : b3684; hypothetical protein 1801647..1802345 Escherichia coli CFT073 1035901 NP_753856.2 CDS ydeD NC_004431.1 1802390 1803289 R Escherichia coli K-12 ortholog: b1533; Escherichia coli O157:H7 ortholog: z2168; O-acetylserine/cysteine export protein complement(1802390..1803289) Escherichia coli CFT073 1035904 NP_753857.1 CDS ydeF NC_004431.1 1803484 1804671 D YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; MFS-type transporter YdeE 1803484..1804671 Escherichia coli CFT073 1035907 NP_753858.1 CDS ydeH NC_004431.1 1805113 1806009 R Escherichia coli K-12 ortholog: b1535; Escherichia coli O157:H7 ortholog: z2163; hypothetical protein complement(1805113..1806009) Escherichia coli CFT073 1035908 NP_753859.1 CDS dcp NC_004431.1 1806510 1808621 R Escherichia coli K-12 ortholog: b1538; Escherichia coli O157:H7 ortholog: z2160; dipeptidyl carboxypeptidase II complement(1806510..1808621) Escherichia coli CFT073 1035911 NP_753860.1 CDS ydfG NC_004431.1 1808677 1809438 D NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 1808677..1809438 Escherichia coli CFT073 1035913 NP_753861.1 CDS ydfH NC_004431.1 1809527 1810213 D Escherichia coli K-12 ortholog: b1540; Escherichia coli O157:H7 ortholog: z2157; transcriptional regulator YdfH 1809527..1810213 Escherichia coli CFT073 1035915 NP_753862.1 CDS ydfZ NC_004431.1 1810390 1810593 D Escherichia coli K-12 ortholog: b1541; Escherichia coli O157:H7 ortholog: z2156; hypothetical protein 1810390..1810593 Escherichia coli CFT073 1035916 NP_753863.1 CDS c1968 NC_004431.1 1810629 1812089 R Escherichia coli K-12 ortholog: b1542; Escherichia coli O157:H7 ortholog: z2155; oxidoreductase ydfI complement(1810629..1812089) Escherichia coli CFT073 1035921 NP_753864.1 CDS ydfJ NC_004431.1 1812178 1813545 R Escherichia coli K-12 ortholog: b1543; Escherichia coli O157:H7 ortholog: z2153; metabolite transport protein complement(1812178..1813545) Escherichia coli CFT073 1035922 NP_753865.2 CDS rspB NC_004431.1 1813603 1814622 R Escherichia coli K-12 ortholog: b1580; dehydrogenase complement(1813603..1814622) Escherichia coli CFT073 1035923 NP_753866.1 CDS rspA NC_004431.1 1814634 1815881 R Escherichia coli K-12 ortholog: b1581; starvation sensing protein rspA complement(1814634..1815881) Escherichia coli CFT073 1035931 NP_753867.1 CDS ynfA NC_004431.1 1816054 1816389 R Escherichia coli K-12 ortholog: b1582; Escherichia coli O157:H7 ortholog: z2569; hypothetical protein complement(1816054..1816389) Escherichia coli CFT073 1035935 NP_753868.1 CDS ynfB NC_004431.1 1816515 1816856 D Escherichia coli K-12 ortholog: b1583; Escherichia coli O157:H7 ortholog: z2570; hypothetical protein 1816515..1816856 Escherichia coli CFT073 1035945 NP_753869.1 CDS speG NC_004431.1 1816891 1817451 D Escherichia coli K-12 ortholog: b1584; Escherichia coli O157:H7 ortholog: z2571; spermidine N(1)-acetyltransferase 1816891..1817451 Escherichia coli CFT073 1035948 NP_753870.2 CDS ynfC NC_004431.1 1817454 1818164 R Escherichia coli K-12 ortholog: b1585; Escherichia coli O157:H7 ortholog: z2572; hypothetical protein complement(1817454..1818164) Escherichia coli CFT073 1035952 NP_753871.1 CDS ynfD NC_004431.1 1818230 1818577 D Escherichia coli K-12 ortholog: b1586; Escherichia coli O157:H7 ortholog: z2573; hypothetical protein 1818230..1818577 Escherichia coli CFT073 1035953 NP_753872.1 CDS ynfE NC_004431.1 1818776 1821202 D Escherichia coli K-12 ortholog: b1587; Escherichia coli O157:H7 ortholog: z2575; dimethyl sulfoxide reductase chain ynfE 1818776..1821202 Escherichia coli CFT073 1035954 NP_753873.1 CDS ynfF NC_004431.1 1821260 1823686 D Escherichia coli K-12 ortholog: b1588; Escherichia coli O157:H7 ortholog: z2576; dimethyl sulfoxide reductase chain ynfF 1821260..1823686 Escherichia coli CFT073 1035955 NP_753874.1 CDS ynfG NC_004431.1 1823697 1824314 D DMSO reductase iron-sulfur subunit ynfG; Escherichia coli K-12 ortholog: b1589; Escherichia coli O157:H7 ortholog: z2577; anaerobic dimethyl sulfoxide reductase chain ynfG 1823697..1824314 Escherichia coli CFT073 1035960 NP_753875.1 CDS c1980 NC_004431.1 1824295 1824441 R hypothetical protein complement(1824295..1824441) Escherichia coli CFT073 1035967 NP_753876.1 CDS ynfH NC_004431.1 1824316 1825170 D DMSO reductase anchor subunit ynfH; Escherichia coli K-12 ortholog: b1590; Escherichia coli O157:H7 ortholog: z2579; anaerobic dimethyl sulfoxide reductase chain ynfH 1824316..1825170 Escherichia coli CFT073 1035970 NP_753877.2 CDS ynfI NC_004431.1 1825213 1825827 D binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 1825213..1825827 Escherichia coli CFT073 1035971 NP_753878.2 CDS ynfJ NC_004431.1 1826022 1827278 D Escherichia coli K-12 ortholog: b1592; Escherichia coli O157:H7 ortholog: z2583; voltage-gated ClC-type chloride channel ClcB 1826022..1827278 Escherichia coli CFT073 1035974 NP_753879.2 CDS bioD NC_004431.1 1827231 1827926 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase complement(1827231..1827926) Escherichia coli CFT073 1035979 NP_753880.1 CDS mlc NC_004431.1 1828051 1829271 R Making large colonies protein; Escherichia coli K-12 ortholog: b1594; Escherichia coli O157:H7 ortholog: z2587; Mlc protein complement(1828051..1829271) Escherichia coli CFT073 1035983 NP_753881.1 CDS ynfL NC_004431.1 1829406 1830299 R Escherichia coli K-12 ortholog: b1595; Escherichia coli O157:H7 ortholog: z2589; transcriptional regulator YnfL complement(1829406..1830299) Escherichia coli CFT073 1035984 NP_753882.1 CDS ynfM NC_004431.1 1830406 1831659 D Escherichia coli K-12 ortholog: b1596; Escherichia coli O157:H7 ortholog: z2590; transport protein YnfM 1830406..1831659 Escherichia coli CFT073 1035986 NP_753883.2 CDS asr NC_004431.1 1832071 1832379 D required for growth and survival under moderately acid conditions; acid shock protein 1832071..1832379 Escherichia coli CFT073 1035987 YP_004853811.1 CDS c1989 NC_004431.1 1832093 1832470 D acid shock protein 1832093..1832470 Escherichia coli CFT073 1035990 NP_753885.1 CDS c1990 NC_004431.1 1832655 1833476 D Escherichia coli K-12 ortholog: b1598; Escherichia coli O157:H7 ortholog: z2592; protease ydgD 1832655..1833476 Escherichia coli CFT073 1036003 NP_753886.1 CDS ydgE NC_004431.1 1833515 1833844 R with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI complement(1833515..1833844) Escherichia coli CFT073 1036006 NP_753887.1 CDS ydgF NC_004431.1 1833831 1834196 R with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtJ complement(1833831..1834196) Escherichia coli CFT073 1036008 NP_753888.1 CDS tqsA NC_004431.1 1834608 1835642 D transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; transport protein 1834608..1835642 Escherichia coli CFT073 1036021 NP_753889.1 CDS pntB NC_004431.1 1835667 1837055 R catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase complement(1835667..1837055) Escherichia coli CFT073 1036023 NP_753890.1 CDS pntA NC_004431.1 1837066 1838652 R forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha complement(1837066..1838652) Escherichia coli CFT073 1036024 NP_753891.1 CDS ydgH NC_004431.1 1839122 1840066 D Escherichia coli K-12 ortholog: b1604; Escherichia coli O157:H7 ortholog: z2603; hypothetical protein 1839122..1840066 Escherichia coli CFT073 1036026 NP_753892.1 CDS ydgI NC_004431.1 1840225 1841634 D Escherichia coli K-12 ortholog: b1605; Escherichia coli O157:H7 ortholog: z2605; arginine/ornithine antiporter 1840225..1841634 Escherichia coli CFT073 1036027 NP_753893.1 CDS ydgB NC_004431.1 1841671 1842393 D Escherichia coli K-12 ortholog: b1606; Escherichia coli O157:H7 ortholog: z2606; short chain dehydrogenase 1841671..1842393 Escherichia coli CFT073 1036028 NP_753894.1 CDS ydgC NC_004431.1 1842390 1842725 R Escherichia coli K-12 ortholog: b1607; Escherichia coli O157:H7 ortholog: z2608; hypothetical protein complement(1842390..1842725) Escherichia coli CFT073 1036032 NP_753895.1 CDS rstA NC_004431.1 1842794 1843573 D response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 1842794..1843573 Escherichia coli CFT073 1036033 NP_753896.1 CDS rstB NC_004431.1 1843577 1844878 D Escherichia coli K-12 ortholog: b1609; Escherichia coli O157:H7 ortholog: z2610; sensor protein RstB 1843577..1844878 Escherichia coli CFT073 1036038 NP_753897.1 CDS tus NC_004431.1 1844942 1845883 D binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 1844942..1845883 Escherichia coli CFT073 1036040 NP_753898.1 CDS fumC NC_004431.1 1845880 1847283 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(1845880..1847283) Escherichia coli CFT073 1036041 NP_753899.1 CDS fumA NC_004431.1 1847426 1849072 R Escherichia coli K-12 ortholog: b1612; Escherichia coli O157:H7 ortholog: z2615; fumarate hydratase class I, aerobic complement(1847426..1849072) Escherichia coli CFT073 1036044 NP_753900.1 CDS manA NC_004431.1 1849271 1850446 D Escherichia coli K-12 ortholog: b1613; Escherichia coli O157:H7 ortholog: z2616; mannose-6-phosphate isomerase 1849271..1850446 Escherichia coli CFT073 1036047 NP_753901.1 CDS ydgA NC_004431.1 1850547 1852055 D Escherichia coli K-12 ortholog: b1614; Escherichia coli O157:H7 ortholog: z2617; hypothetical protein 1850547..1852055 Escherichia coli CFT073 1036048 NP_753902.1 CDS uidC NC_004431.1 1852100 1853365 R Escherichia coli K-12 ortholog: b1615; Escherichia coli O157:H7 ortholog: z2619; outer membrane porin protein complement(1852100..1853365) Escherichia coli CFT073 1036053 NP_753903.1 CDS uidB NC_004431.1 1853404 1854777 R Glucuronide permease; Escherichia coli K-12 ortholog: b1616; Escherichia coli O157:H7 ortholog: z2620; glucuronide transporter complement(1853404..1854777) Escherichia coli CFT073 1036058 NP_753904.1 CDS uidA NC_004431.1 1854774 1856585 R Escherichia coli K-12 ortholog: b1617; Escherichia coli O157:H7 ortholog: z2621; beta-D-glucuronidase complement(1854774..1856585) Escherichia coli CFT073 1036059 NP_753905.1 CDS uidR NC_004431.1 1856975 1857565 R Gus operon repressor; Escherichia coli K-12 ortholog: b1618; Escherichia coli O157:H7 ortholog: z2623; uid operon repressor complement(1856975..1857565) Escherichia coli CFT073 1036061 NP_753906.1 CDS hdhA NC_004431.1 1857794 1858561 R Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase complement(1857794..1858561) Escherichia coli CFT073 1036064 NP_753907.1 CDS malI NC_004431.1 1858673 1859701 R regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI complement(1858673..1859701) Escherichia coli CFT073 1036066 NP_753908.2 CDS malX NC_004431.1 1859876 1861468 D phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; bifunctional PTS system maltose and glucose-specific transporter subunits IICB 1859876..1861468 Escherichia coli CFT073 1036069 NP_753909.1 CDS malY NC_004431.1 1861478 1862650 D Escherichia coli K-12 ortholog: b1622; Escherichia coli O157:H7 ortholog: z2627; bifunctional; cystathionine beta-lyase 1861478..1862650 Escherichia coli CFT073 1036071 NP_753910.1 CDS add NC_004431.1 1862754 1863755 D catalyzes the formation of inosine from adenosine; adenosine deaminase 1862754..1863755 Escherichia coli CFT073 1036085 NP_753911.2 CDS ydgJ NC_004431.1 1863791 1864831 R Escherichia coli K-12 ortholog: b1624; Escherichia coli O157:H7 ortholog: z2629; oxidoreductase complement(1863791..1864831) Escherichia coli CFT073 1036088 NP_753912.1 CDS ydgT NC_004431.1 1865472 1865687 D YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 1865472..1865687 Escherichia coli CFT073 1036093 NP_753913.1 CDS ydgK NC_004431.1 1865749 1866213 D Escherichia coli K-12 ortholog: b1626; Escherichia coli O157:H7 ortholog: z2632; hypothetical protein 1865749..1866213 Escherichia coli CFT073 1036094 NP_753914.1 CDS c2019 NC_004431.1 1866290 1866871 D Escherichia coli K-12 ortholog: b1627; Escherichia coli O157:H7 ortholog: z2633; Na(+)-translocating NADH-quinone reductase subunit E 1866290..1866871 Escherichia coli CFT073 1036103 NP_753915.1 CDS c2020 NC_004431.1 1866871 1867449 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1866871..1867449 Escherichia coli CFT073 1036107 NP_753916.1 CDS c2021 NC_004431.1 1867442 1869670 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1867442..1869670 Escherichia coli CFT073 1036108 NP_753917.1 CDS rnfD NC_004431.1 1869671 1870729 D RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1869671..1870729 Escherichia coli CFT073 1036112 NP_753918.1 CDS c2023 NC_004431.1 1870733 1871353 D part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1870733..1871353 Escherichia coli CFT073 1036113 NP_753919.1 CDS ydgQ NC_004431.1 1871357 1872052 D in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex RsxE subunit 1871357..1872052 Escherichia coli CFT073 1036115 NP_753920.1 CDS nth NC_004431.1 1872052 1872687 D DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 1872052..1872687 Escherichia coli CFT073 1036116 NP_753921.1 CDS tppB NC_004431.1 1873298 1874800 D mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; tripeptide transporter permease 1873298..1874800 Escherichia coli CFT073 1036118 NP_753922.1 CDS gst NC_004431.1 1874906 1875511 D Escherichia coli K-12 ortholog: b1635; Escherichia coli O157:H7 ortholog: z2647; glutathionine S-transferase 1874906..1875511 Escherichia coli CFT073 1036120 NP_753923.1 CDS pdxY NC_004431.1 1875555 1876418 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase complement(1875555..1876418) Escherichia coli CFT073 1036121 NP_753924.1 CDS tyrS NC_004431.1 1876477 1877763 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(1876477..1877763) Escherichia coli CFT073 1036124 NP_753925.1 CDS pdxH NC_004431.1 1877880 1878536 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase complement(1877880..1878536) Escherichia coli CFT073 1036125 NP_753926.1 CDS ydhA NC_004431.1 1878595 1878924 R MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor complement(1878595..1878924) Escherichia coli CFT073 1036129 NP_753927.1 CDS anmK NC_004431.1 1879022 1880131 R catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase complement(1879022..1880131) Escherichia coli CFT073 1036131 NP_753928.1 CDS slyB NC_004431.1 1880405 1880872 D Escherichia coli K-12 ortholog: b1641; Escherichia coli O157:H7 ortholog: z2655; outer membrane lipoprotein slyB 1880405..1880872 Escherichia coli CFT073 1036133 NP_753929.2 CDS slyA NC_004431.1 1880919 1881353 R Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA complement(1880919..1881353) Escherichia coli CFT073 1036136 NP_753930.1 CDS ydhI NC_004431.1 1881554 1881790 D Escherichia coli K-12 ortholog: b1643; Escherichia coli O157:H7 ortholog: z2658; hypothetical protein 1881554..1881790 Escherichia coli CFT073 1036138 NP_753931.1 CDS ydhJ NC_004431.1 1881751 1882650 D Escherichia coli K-12 ortholog: b1644; Escherichia coli O157:H7 ortholog: z2659; hypothetical protein 1881751..1882650 Escherichia coli CFT073 1036140 NP_753932.1 CDS ydhK NC_004431.1 1882650 1884662 D Escherichia coli K-12 ortholog: b1645; Escherichia coli O157:H7 ortholog: z2660; hypothetical protein 1882650..1884662 Escherichia coli CFT073 1036142 NP_753933.1 CDS sodC NC_004431.1 1884663 1885235 R SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase complement(1884663..1885235) Escherichia coli CFT073 1036143 NP_753934.1 CDS ydhF NC_004431.1 1885265 1886161 R Escherichia coli K-12 ortholog: b1647; Escherichia coli O157:H7 ortholog: z2664; oxidoreductase ydhF complement(1885265..1886161) Escherichia coli CFT073 1036144 NP_753935.1 CDS ydhL NC_004431.1 1886210 1886587 R Escherichia coli K-12 ortholog: b1648; Escherichia coli O157:H7 ortholog: z2665; hypothetical protein complement(1886210..1886587) Escherichia coli CFT073 1036146 NP_753936.1 CDS c2041 NC_004431.1 1886218 1886340 D hypothetical protein 1886218..1886340 Escherichia coli CFT073 1036148 NP_753937.1 CDS ydhM NC_004431.1 1886552 1887151 D Escherichia coli K-12 ortholog: b1649; Escherichia coli O157:H7 ortholog: z2666; transcriptional regulator YdhM 1886552..1887151 Escherichia coli CFT073 1036152 NP_753938.1 CDS nemA NC_004431.1 1887188 1888285 D FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 1887188..1888285 Escherichia coli CFT073 1036153 NP_753939.1 CDS gloA NC_004431.1 1888366 1888773 D Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 1888366..1888773 Escherichia coli CFT073 1036158 NP_753940.1 CDS rnt NC_004431.1 1888876 1889523 D Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 1888876..1889523 Escherichia coli CFT073 1036159 NP_753941.1 CDS c2046 NC_004431.1 1889585 1889728 R hypothetical protein complement(1889585..1889728) Escherichia coli CFT073 1036162 NP_753942.1 CDS c2047 NC_004431.1 1889616 1889759 D Residues 1 to 37 of 47 are 94.59 pct identical to residues 1 to 37 of 1538 from GenPept.129 : >gb|AAG56642.1|AE005388_7 (AE005388) member of ATP-dependent helicase superfamily II [Escherichia coli O157:H7 EDL933]; hypothetical protein 1889616..1889759 Escherichia coli CFT073 1036172 NP_753943.1 CDS ydhD NC_004431.1 1889895 1890242 R Escherichia coli K-12 ortholog: b1654; Escherichia coli O157:H7 ortholog: z2676; hypothetical protein complement(1889895..1890242) Escherichia coli CFT073 1036173 NP_753944.1 CDS ydhO NC_004431.1 1890577 1891404 D Escherichia coli K-12 ortholog: b1655; Escherichia coli O157:H7 ortholog: z2677; hypothetical protein 1890577..1891404 Escherichia coli CFT073 1036176 NP_753945.1 CDS sodB NC_004431.1 1891532 1892113 D SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 1891532..1892113 Escherichia coli CFT073 1036179 NP_753946.1 CDS ydhP NC_004431.1 1892259 1893428 R Escherichia coli K-12 ortholog: b1657; Escherichia coli O157:H7 ortholog: z2679; transport protein YdhP complement(1892259..1893428) Escherichia coli CFT073 1036180 NP_753947.1 CDS purR NC_004431.1 1893982 1895007 D binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1893982..1895007 Escherichia coli CFT073 1036187 NP_753948.1 CDS ydhB NC_004431.1 1895004 1895936 R Escherichia coli K-12 ortholog: b1659; Escherichia coli O157:H7 ortholog: z2682; DNA-binding transcriptional regulator complement(1895004..1895936) Escherichia coli CFT073 1036190 NP_753949.1 CDS ydhC NC_004431.1 1896049 1897260 D uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 1896049..1897260 Escherichia coli CFT073 1036194 NP_753950.1 CDS cfa NC_004431.1 1897551 1898699 D catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane fatty acyl phospholipid synthase 1897551..1898699 Escherichia coli CFT073 1036202 NP_753951.1 CDS ribE NC_004431.1 1898739 1899380 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(1898739..1899380) Escherichia coli CFT073 1036204 NP_753952.1 CDS ydhE NC_004431.1 1899595 1900968 D NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1899595..1900968 Escherichia coli CFT073 1036205 NP_753953.1 CDS ydhQ NC_004431.1 1901009 1902265 R Escherichia coli K-12 ortholog: b1664; Escherichia coli O157:H7 ortholog: z2691; hypothetical protein complement(1901009..1902265) Escherichia coli CFT073 1036207 NP_753954.1 CDS c2059 NC_004431.1 1902839 1903144 D Escherichia coli K-12 ortholog: b1667; Escherichia coli O157:H7 ortholog: z2694; hypothetical protein 1902839..1903144 Escherichia coli CFT073 1036218 NP_753955.1 CDS ydhS NC_004431.1 1903270 1904880 D Escherichia coli K-12 ortholog: b1668; Escherichia coli O157:H7 ortholog: z2695; hypothetical protein 1903270..1904880 Escherichia coli CFT073 1036219 NP_753956.1 CDS c2061 NC_004431.1 1904867 1904992 R hypothetical protein complement(1904867..1904992) Escherichia coli CFT073 1036221 NP_753957.1 CDS ydhT NC_004431.1 1904886 1905698 R Escherichia coli K-12 ortholog: b1669; Escherichia coli O157:H7 ortholog: z2696; hypothetical protein complement(1904886..1905698) Escherichia coli CFT073 1036223 NP_753958.1 CDS c2063 NC_004431.1 1905087 1905833 D hypothetical protein 1905087..1905833 Escherichia coli CFT073 1036226 NP_753959.1 CDS ydhU NC_004431.1 1905702 1906487 R Escherichia coli K-12 ortholog: b1670; Escherichia coli O157:H7 ortholog: z2697; PhsC protein complement(1905702..1906487) Escherichia coli CFT073 1036229 NP_753960.1 CDS c2065 NC_004431.1 1906484 1907203 R Escherichia coli K-12 ortholog: b1671; Escherichia coli O157:H7 ortholog: z2698; ferredoxin-like protein ydhX complement(1906484..1907203) Escherichia coli CFT073 1036236 NP_753961.1 CDS ydhW NC_004431.1 1907216 1907863 R Escherichia coli K-12 ortholog: b1672; Escherichia coli O157:H7 ortholog: z2700; hypothetical protein complement(1907216..1907863) Escherichia coli CFT073 1036238 NP_753962.2 CDS ydhV NC_004431.1 1907867 1909969 R Escherichia coli K-12 ortholog: b1673; Escherichia coli O157:H7 ortholog: z2701; oxidoreductase complement(1907867..1909969) Escherichia coli CFT073 1036243 NP_753963.1 CDS c2068 NC_004431.1 1909990 1910616 R Escherichia coli K-12 ortholog: b1674; Escherichia coli O157:H7 ortholog: z2702; hypothetical protein complement(1909990..1910616) Escherichia coli CFT073 1036249 NP_753964.1 CDS ydhZ NC_004431.1 1911072 1911281 R Escherichia coli K-12 ortholog: b1675; Escherichia coli O157:H7 ortholog: z2703; hypothetical protein complement(1911072..1911281) Escherichia coli CFT073 1036251 NP_753965.1 CDS c2070 NC_004431.1 1911393 1911521 D hypothetical protein 1911393..1911521 Escherichia coli CFT073 1036254 NP_753966.1 CDS pykF NC_004431.1 1911623 1913251 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1911623..1913251 Escherichia coli CFT073 1036261 NP_753967.1 CDS lpp NC_004431.1 1913562 1913798 D Murein-lipoprotein; Escherichia coli K-12 ortholog: b1677; Escherichia coli O157:H7 ortholog: z2705; major outer membrane lipoprotein 1913562..1913798 Escherichia coli CFT073 1036271 NP_753968.1 CDS ynhG NC_004431.1 1913861 1914865 R Escherichia coli K-12 ortholog: b1678; Escherichia coli O157:H7 ortholog: z2706; hypothetical protein complement(1913861..1914865) Escherichia coli CFT073 1036272 NP_753969.1 CDS ynhA NC_004431.1 1915014 1915430 R Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE complement(1915014..1915430) Escherichia coli CFT073 1036273 NP_753970.1 CDS c2075 NC_004431.1 1915443 1916663 R catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase complement(1915443..1916663) Escherichia coli CFT073 1036285 NP_753971.1 CDS ynhC NC_004431.1 1916660 1917931 R with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD complement(1916660..1917931) Escherichia coli CFT073 1036312 NP_753972.1 CDS sufC NC_004431.1 1917906 1918652 R part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase ATPase component complement(1917906..1918652) Escherichia coli CFT073 1036316 NP_753973.1 CDS ynhE NC_004431.1 1918662 1920188 R with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB complement(1918662..1920188) Escherichia coli CFT073 1036318 NP_753974.1 CDS sufA NC_004431.1 1920158 1920526 R functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein complement(1920158..1920526) Escherichia coli CFT073 1036331 NP_753975.1 CDS ydiH NC_004431.1 1921075 1921344 R Escherichia coli K-12 ortholog: b1685; Escherichia coli O157:H7 ortholog: z2713; hypothetical protein complement(1921075..1921344) Escherichia coli CFT073 1036340 NP_753976.1 CDS ydiI NC_004431.1 1921363 1921773 R Escherichia coli K-12 ortholog: b1686; Escherichia coli O157:H7 ortholog: z2714; hypothetical protein complement(1921363..1921773) Escherichia coli CFT073 1036342 NP_753977.1 CDS ydiJ NC_004431.1 1921770 1924826 R Escherichia coli K-12 ortholog: b1687; Escherichia coli O157:H7 ortholog: z2715; hypothetical protein complement(1921770..1924826) Escherichia coli CFT073 1036348 NP_753978.1 CDS ydiK NC_004431.1 1925040 1926152 D YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; inner membrane protein 1925040..1926152 Escherichia coli CFT073 1036354 NP_753979.1 CDS ydiL NC_004431.1 1926554 1926937 D Escherichia coli K-12 ortholog: b1689; Escherichia coli O157:H7 ortholog: z2717; hypothetical protein 1926554..1926937 Escherichia coli CFT073 1036357 NP_753980.1 CDS ydiM NC_004431.1 1927037 1928251 D Escherichia coli K-12 ortholog: b1690; Escherichia coli O157:H7 ortholog: z2718; transport protein YdiM 1927037..1928251 Escherichia coli CFT073 1036359 NP_753981.1 CDS ydiN NC_004431.1 1928472 1929743 D Escherichia coli K-12 ortholog: b1691; Escherichia coli O157:H7 ortholog: z2719; transport protein YdiN 1928472..1929743 Escherichia coli CFT073 1036365 NP_753982.1 CDS aroE NC_004431.1 1929755 1930621 D YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 1929755..1930621 Escherichia coli CFT073 1036366 NP_753983.1 CDS aroD NC_004431.1 1930652 1931410 D catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1930652..1931410 Escherichia coli CFT073 1036367 NP_753984.1 CDS ydiF NC_004431.1 1931556 1933151 D Escherichia coli K-12 ortholog: b1694; Escherichia coli O157:H7 ortholog: z2722; hypothetical protein 1931556..1933151 Escherichia coli CFT073 1036370 NP_753985.2 CDS ydiO NC_004431.1 1933165 1934316 D may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; acyl-CoA dehydrogenase 1933165..1934316 Escherichia coli CFT073 1036372 NP_753986.1 CDS ydiP NC_004431.1 1934359 1935270 R Escherichia coli K-12 ortholog: b1696; Escherichia coli O157:H7 ortholog: z2724; transcriptional regulator YdiP complement(1934359..1935270) Escherichia coli CFT073 1036377 NP_753987.1 CDS c2092 NC_004431.1 1935373 1935549 R hypothetical protein complement(1935373..1935549) Escherichia coli CFT073 1036386 NP_753988.2 CDS ydiQ NC_004431.1 1935586 1936350 D YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; electron transfer flavoprotein YdiQ 1935586..1936350 Escherichia coli CFT073 1036390 NP_753989.1 CDS ydiR NC_004431.1 1936370 1937308 D May play a role in a redox process; electron transfer flavoprotein subunit YdiR 1936370..1937308 Escherichia coli CFT073 1036391 NP_753990.1 CDS ydiS NC_004431.1 1937363 1938652 D Escherichia coli K-12 ortholog: b1699; Escherichia coli O157:H7 ortholog: z2728; hypothetical protein 1937363..1938652 Escherichia coli CFT073 1036392 NP_753991.1 CDS ydiT NC_004431.1 1938649 1938942 D Escherichia coli K-12 ortholog: b1700; Escherichia coli O157:H7 ortholog: z2729; ferredoxin-like protein ydiT 1938649..1938942 Escherichia coli CFT073 1036395 NP_753992.1 CDS ydiD NC_004431.1 1938945 1940645 D acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids; short chain acyl-CoA synthetase 1938945..1940645 Escherichia coli CFT073 1036396 NP_753993.1 CDS ppsA NC_004431.1 1940702 1943080 R catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase complement(1940702..1943080) Escherichia coli CFT073 1036397 NP_753994.1 CDS ydiA NC_004431.1 1943413 1944246 D Escherichia coli K-12 ortholog: b1703; Escherichia coli O157:H7 ortholog: z2732; hypothetical protein 1943413..1944246 Escherichia coli CFT073 1036398 NP_753995.1 CDS aroH NC_004431.1 1944403 1945449 D tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 1944403..1945449 Escherichia coli CFT073 1036404 NP_753996.1 CDS ydiE NC_004431.1 1945554 1945772 D Escherichia coli K-12 ortholog: b1705; Escherichia coli O157:H7 ortholog: z2734; hypothetical protein 1945554..1945772 Escherichia coli CFT073 1036409 NP_753997.1 CDS ydiU NC_004431.1 1945776 1947212 R Escherichia coli K-12 ortholog: b1706; Escherichia coli O157:H7 ortholog: z2735; hypothetical protein complement(1945776..1947212) Escherichia coli CFT073 1036411 NP_753998.1 CDS ydiV NC_004431.1 1947275 1947988 R Escherichia coli K-12 ortholog: b1707; Escherichia coli O157:H7 ortholog: z2736; hypothetical protein complement(1947275..1947988) Escherichia coli CFT073 1036412 NP_753999.1 CDS nlpC NC_004431.1 1948235 1948699 R ORF-17; Escherichia coli K-12 ortholog: b1708; Escherichia coli O157:H7 ortholog: z2737; lipoprotein NlpC complement(1948235..1948699) Escherichia coli CFT073 1036414 NP_754000.1 CDS btuD NC_004431.1 1948777 1949526 R ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase complement(1948777..1949526) Escherichia coli CFT073 1036415 NP_754001.1 CDS btuE NC_004431.1 1949526 1950077 R similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; glutathione peroxidase complement(1949526..1950077) Escherichia coli CFT073 1036421 NP_754002.1 CDS btuC NC_004431.1 1950139 1951119 R with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease complement(1950139..1951119) Escherichia coli CFT073 1036429 NP_754003.1 CDS c2108 NC_004431.1 1951016 1951144 R hypothetical protein complement(1951016..1951144) Escherichia coli CFT073 1036431 NP_754004.1 CDS ihfA NC_004431.1 1951220 1951519 R This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha complement(1951220..1951519) Escherichia coli CFT073 1036432 NP_754005.2 CDS pheS NC_004431.1 1953927 1954910 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha complement(1953927..1954910) Escherichia coli CFT073 1036438 NP_754007.1 CDS rplT NC_004431.1 1955361 1955717 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(1955361..1955717) Escherichia coli CFT073 1036447 NP_754008.1 CDS c2114 NC_004431.1 1955839 1956450 D hypothetical protein 1955839..1956450 Escherichia coli CFT073 1036451 NP_754009.1 CDS infC NC_004431.1 1956064 1956498 R IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 complement(1956064..1956498) Escherichia coli CFT073 1036455 NP_754010.1 CDS thrS NC_004431.1 1956610 1958538 R catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase complement(1956610..1958538) Escherichia coli CFT073 1036459 NP_754011.1 CDS c2117 NC_004431.1 1959224 1959589 D Residues 12 to 97 of 121 are 88.37 pct identical to residues 66 to 151 of 157 from MG1655 : b1720; hypothetical protein 1959224..1959589 Escherichia coli CFT073 1036467 NP_754012.1 CDS c2118 NC_004431.1 1959607 1959918 D Residues 1 to 83 of 103 are 93.97 pct identical to residues 22 to 104 of 471 from MG1655 : b1721; hypothetical protein 1959607..1959918 Escherichia coli CFT073 1036473 NP_754013.1 CDS c2119 NC_004431.1 1959899 1960090 D Residues 2 to 63 of 63 are 93.54 pct identical to residues 571 to 632 of 632 from GenPept.129 : >gb|AAG56707.1|AE005395_3 (AE005395) Z2749 gene product [Escherichia coli O157:H7 EDL933]; hypothetical protein 1959899..1960090 Escherichia coli CFT073 1036480 NP_754014.1 CDS ydiY NC_004431.1 1960421 1961179 R Escherichia coli K-12 ortholog: b1722; Escherichia coli O157:H7 ortholog: z2751; hypothetical protein complement(1960421..1961179) Escherichia coli CFT073 1036495 NP_754015.1 CDS pfkB NC_004431.1 1961463 1962395 D Escherichia coli K-12 ortholog: b1723; Escherichia coli O157:H7 ortholog: z2752; 6-phosphofructokinase 1961463..1962395 Escherichia coli CFT073 1036501 NP_754016.1 CDS c2122 NC_004431.1 1962424 1962801 R hypothetical protein complement(1962424..1962801) Escherichia coli CFT073 1036510 NP_754017.1 CDS ydiZ NC_004431.1 1962496 1962786 D Escherichia coli K-12 ortholog: b1724; Escherichia coli O157:H7 ortholog: z2753; hypothetical protein 1962496..1962786 Escherichia coli CFT073 1036522 NP_754018.1 CDS yniA NC_004431.1 1962892 1963752 D Escherichia coli K-12 ortholog: b1725; Escherichia coli O157:H7 ortholog: z2754; hypothetical protein 1962892..1963752 Escherichia coli CFT073 1036523 NP_754019.1 CDS yniB NC_004431.1 1963793 1964329 R Escherichia coli K-12 ortholog: b1726; Escherichia coli O157:H7 ortholog: z2755; hypothetical protein complement(1963793..1964329) Escherichia coli CFT073 1036524 NP_754020.1 CDS yniC NC_004431.1 1964476 1965144 D YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 1964476..1965144 Escherichia coli CFT073 1036526 NP_754021.2 CDS ydjM NC_004431.1 1965308 1965898 D Escherichia coli K-12 ortholog: b1728; Escherichia coli O157:H7 ortholog: z2757; hypothetical protein 1965308..1965898 Escherichia coli CFT073 1036530 NP_754022.1 CDS ydjN NC_004431.1 1966031 1967422 D Escherichia coli K-12 ortholog: b1729; Escherichia coli O157:H7 ortholog: z2758; symporter ydjN 1966031..1967422 Escherichia coli CFT073 1036532 NP_754023.1 CDS c2129 NC_004431.1 1967469 1967732 R Escherichia coli K-12 ortholog: b1731; Escherichia coli O157:H7 ortholog: z2760; cell division modulator complement(1967469..1967732) Escherichia coli CFT073 1036535 NP_754024.1 CDS c2130 NC_004431.1 1967898 1968056 R hypothetical protein complement(1967898..1968056) Escherichia coli CFT073 1036536 NP_754025.1 CDS katE NC_004431.1 1967915 1970176 D Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 1967915..1970176 Escherichia coli CFT073 1036537 NP_754026.1 CDS ydjC NC_004431.1 1970223 1970981 R Escherichia coli K-12 ortholog: b1733; Escherichia coli O157:H7 ortholog: z2763; hypothetical protein complement(1970223..1970981) Escherichia coli CFT073 1036539 NP_754027.1 CDS celF NC_004431.1 1970994 1972400 R Escherichia coli K-12 ortholog: b1734; Escherichia coli O157:H7 ortholog: z2764; 6-phospho-beta-glucosidase complement(1970994..1972400) Escherichia coli CFT073 1036543 NP_754028.1 CDS celD NC_004431.1 1972449 1973291 R represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR complement(1972449..1973291) Escherichia coli CFT073 1036544 NP_754029.1 CDS celC NC_004431.1 1973299 1973649 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA complement(1973299..1973649) Escherichia coli CFT073 1036547 NP_754030.1 CDS celB NC_004431.1 1973700 1975058 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC complement(1973700..1975058) Escherichia coli CFT073 1036548 NP_754031.1 CDS celA NC_004431.1 1975143 1975463 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB complement(1975143..1975463) Escherichia coli CFT073 1036550 NP_754032.1 CDS osmE NC_004431.1 1975763 1976101 R osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE complement(1975763..1976101) Escherichia coli CFT073 1036554 NP_754033.1 CDS nadE NC_004431.1 1976303 1977130 D catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1976303..1977130 Escherichia coli CFT073 1036556 NP_754034.1 CDS ydjQ NC_004431.1 1977360 1978247 D 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 1977360..1978247 Escherichia coli CFT073 1036559 NP_754035.1 CDS ydjR NC_004431.1 1978207 1978845 R Escherichia coli K-12 ortholog: b1742; Escherichia coli O157:H7 ortholog: z2774; hypothetical protein complement(1978207..1978845) Escherichia coli CFT073 1036563 NP_754036.1 CDS c2142 NC_004431.1 1978973 1979461 D hypothetical protein 1978973..1979461 Escherichia coli CFT073 1036566 NP_754037.1 CDS spy NC_004431.1 1978985 1979470 R periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; periplasmic protein complement(1978985..1979470) Escherichia coli CFT073 1036567 NP_754038.1 CDS ydjS NC_004431.1 1979800 1980768 R catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase complement(1979800..1980768) Escherichia coli CFT073 1036569 NP_754039.1 CDS c2145 NC_004431.1 1980761 1982104 R catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase complement(1980761..1982104) Escherichia coli CFT073 1036570 NP_754040.1 CDS astD NC_004431.1 1982101 1983579 R a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase complement(1982101..1983579) Escherichia coli CFT073 1036571 NP_754041.1 CDS c2147 NC_004431.1 1983663 1984610 R Escherichia coli K-12 ortholog: b1747; Escherichia coli O157:H7 ortholog: z2779; arginine succinyltransferase complement(1983663..1984610) Escherichia coli CFT073 1036572 NP_754042.1 CDS argD NC_004431.1 1984607 1985827 R catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase complement(1984607..1985827) Escherichia coli CFT073 1036573 NP_754043.1 CDS c2149 NC_004431.1 1986090 1986260 D hypothetical protein 1986090..1986260 Escherichia coli CFT073 1036576 NP_754044.2 CDS xthA NC_004431.1 1986273 1987079 D removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1986273..1987079 Escherichia coli CFT073 1036577 NP_754045.1 CDS ydjX NC_004431.1 1987198 1987956 D Escherichia coli K-12 ortholog: b1750; Escherichia coli O157:H7 ortholog: z2782; hypothetical protein 1987198..1987956 Escherichia coli CFT073 1036579 NP_754046.1 CDS ydjY NC_004431.1 1987799 1988638 D Escherichia coli K-12 ortholog: b1751; Escherichia coli O157:H7 ortholog: z2783; hypothetical protein 1987799..1988638 Escherichia coli CFT073 1036581 NP_754047.1 CDS ydjZ NC_004431.1 1988652 1989359 D Escherichia coli K-12 ortholog: b1752; Escherichia coli O157:H7 ortholog: z2784; hypothetical protein 1988652..1989359 Escherichia coli CFT073 1036584 NP_754048.1 CDS ynjA NC_004431.1 1989359 1989907 D Escherichia coli K-12 ortholog: b1753; Escherichia coli O157:H7 ortholog: z2785; hypothetical protein 1989359..1989907 Escherichia coli CFT073 1036585 NP_754049.1 CDS c2155 NC_004431.1 1989917 1991083 D Escherichia coli K-12 ortholog: b1754; Escherichia coli O157:H7 ortholog: z2786; ABC transporter solute-binding protein 1989917..1991083 Escherichia coli CFT073 1036586 NP_754050.1 CDS ynjC NC_004431.1 1991032 1992591 D Escherichia coli K-12 ortholog: b1755; Escherichia coli O157:H7 ortholog: z2787; ABC transporter permease 1991032..1992591 Escherichia coli CFT073 1036588 NP_754051.1 CDS ynjD NC_004431.1 1992558 1993244 D Escherichia coli K-12 ortholog: b1756; Escherichia coli O157:H7 ortholog: z2788; ABC transporter ATP-binding protein 1992558..1993244 Escherichia coli CFT073 1036590 NP_754052.1 CDS c2158 NC_004431.1 1993296 1994618 D Escherichia coli K-12 ortholog: b1757; Escherichia coli O157:H7 ortholog: z2789; thiosulfate sulfurtransferase ynjE 1993296..1994618 Escherichia coli CFT073 1036591 NP_754053.1 CDS ynjF NC_004431.1 1994627 1995253 R Escherichia coli K-12 ortholog: b1758; Escherichia coli O157:H7 ortholog: z2790; hypothetical protein complement(1994627..1995253) Escherichia coli CFT073 1036592 NP_754054.1 CDS c2160 NC_004431.1 1995334 1995741 D Escherichia coli K-12 ortholog: b1759; Escherichia coli O157:H7 ortholog: z2791; pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 1995334..1995741 Escherichia coli CFT073 1036593 NP_754055.1 CDS ynjH NC_004431.1 1995707 1995979 R Escherichia coli K-12 ortholog: b1760; Escherichia coli O157:H7 ortholog: z2792; hypothetical protein complement(1995707..1995979) Escherichia coli CFT073 1036595 NP_754056.1 CDS gdhA NC_004431.1 1996215 1997558 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1996215..1997558 Escherichia coli CFT073 1036597 NP_754057.1 CDS c2163 NC_004431.1 1997614 1999557 R Residues 319 to 628 of 647 are 30.22 pct identical to residues 22 to 328 of 331 from GenPept.129 : >gb|AAL19605.1| (AE008726) TPR repeat protein [Salmonella typhimurium LT2]; hypothetical protein complement(1997614..1999557) Escherichia coli CFT073 1036598 NP_754058.1 CDS ybeW NC_004431.1 1999554 2001254 R Hsc62; Escherichia coli K-12 ortholog: b0650; Escherichia coli O157:H7 ortholog: z0800; chaperone protein hscC complement(1999554..2001254) Escherichia coli CFT073 1036600 NP_754059.1 CDS c2165 NC_004431.1 2001324 2002124 R hypothetical protein complement(2001324..2002124) Escherichia coli CFT073 1036601 NP_754060.1 CDS topB NC_004431.1 2002243 2004246 R decatenates replicating daughter chromosomes; DNA topoisomerase III complement(2002243..2004246) Escherichia coli CFT073 1036602 NP_754061.1 CDS selD NC_004431.1 2004194 2005243 R catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase complement(2004194..2005243) Escherichia coli CFT073 1036603 NP_754062.2 CDS ydjA NC_004431.1 2005354 2005905 R Escherichia coli K-12 ortholog: b1765; Escherichia coli O157:H7 ortholog: z2798; hypothetical protein complement(2005354..2005905) Escherichia coli CFT073 1036604 NP_754063.1 CDS c2169 NC_004431.1 2005959 2006123 D hypothetical protein 2005959..2006123 Escherichia coli CFT073 1036605 NP_754064.1 CDS sppA NC_004431.1 2006066 2007922 D SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 2006066..2007922 Escherichia coli CFT073 1036606 NP_754065.1 CDS ansA NC_004431.1 2008089 2009105 D converts asparagine to aspartate and ammonia; cytoplasmic asparaginase I 2008089..2009105 Escherichia coli CFT073 1036607 NP_754066.2 CDS ydjB NC_004431.1 2009116 2009757 D catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 2009116..2009757 Escherichia coli CFT073 1036608 NP_754067.1 CDS ydjE NC_004431.1 2009850 2011277 R Escherichia coli K-12 ortholog: b1769; Escherichia coli O157:H7 ortholog: z2803; metabolite transporter complement(2009850..2011277) Escherichia coli CFT073 1036610 NP_754068.1 CDS ydjF NC_004431.1 2011326 2012084 R Escherichia coli K-12 ortholog: b1770; Escherichia coli O157:H7 ortholog: z2808; transcriptional regulator YdjF complement(2011326..2012084) Escherichia coli CFT073 1036611 NP_754069.1 CDS ydjG NC_004431.1 2012221 2013201 R Escherichia coli K-12 ortholog: b1771; Escherichia coli O157:H7 ortholog: z2809; oxidoreductase ydjG complement(2012221..2013201) Escherichia coli CFT073 1036613 NP_754070.1 CDS ydjH NC_004431.1 2013211 2014179 R Escherichia coli K-12 ortholog: b1772; Escherichia coli O157:H7 ortholog: z2810; sugar kinase ydjH complement(2013211..2014179) Escherichia coli CFT073 1036614 NP_754071.1 CDS ydjI NC_004431.1 2014163 2014999 R Escherichia coli K-12 ortholog: b1773; Escherichia coli O157:H7 ortholog: z2811; hypothetical protein complement(2014163..2014999) Escherichia coli CFT073 1036615 NP_754072.1 CDS ydjJ NC_004431.1 2015020 2016063 R Escherichia coli K-12 ortholog: b1774; Escherichia coli O157:H7 ortholog: z2812; hypothetical protein complement(2015020..2016063) Escherichia coli CFT073 1036616 NP_754073.1 CDS ydjK NC_004431.1 2016080 2017459 R Escherichia coli K-12 ortholog: b1775; Escherichia coli O157:H7 ortholog: z2813; metabolite transporter complement(2016080..2017459) Escherichia coli CFT073 1036617 NP_754074.1 CDS c2180 NC_004431.1 2017344 2017496 R hypothetical protein complement(2017344..2017496) Escherichia coli CFT073 1036620 NP_754075.1 CDS ydjL NC_004431.1 2017486 2018562 R Escherichia coli K-12 ortholog: b1776; Escherichia coli O157:H7 ortholog: z2815; hypothetical protein complement(2017486..2018562) Escherichia coli CFT073 1036621 NP_754076.1 CDS yeaC NC_004431.1 2018932 2019249 R Escherichia coli K-12 ortholog: b1777; Escherichia coli O157:H7 ortholog: z2816; hypothetical protein complement(2018932..2019249) Escherichia coli CFT073 1036622 NP_754077.1 CDS yeaA NC_004431.1 2019246 2019689 R this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B complement(2019246..2019689) Escherichia coli CFT073 1036623 NP_754078.1 CDS gapA NC_004431.1 2019992 2020996 D catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase 2019992..2020996 Escherichia coli CFT073 1036624 NP_754079.1 CDS yeaD NC_004431.1 2021059 2021964 D Spots T26/PR37; Escherichia coli K-12 ortholog: b1780; Escherichia coli O157:H7 ortholog: z2820; hypothetical protein 2021059..2021964 Escherichia coli CFT073 1036625 NP_754080.1 CDS yeaE NC_004431.1 2022015 2022914 R Escherichia coli K-12 ortholog: b1781; Escherichia coli O157:H7 ortholog: z2821; hypothetical protein complement(2022015..2022914) Escherichia coli CFT073 1036626 NP_754081.1 CDS yeaF NC_004431.1 2022959 2023705 R Escherichia coli K-12 ortholog: b1782; Escherichia coli O157:H7 ortholog: z2822; MltA-interacting protein complement(2022959..2023705) Escherichia coli CFT073 1036627 NP_754082.1 CDS yeaG NC_004431.1 2024141 2026075 D Escherichia coli K-12 ortholog: b1783; Escherichia coli O157:H7 ortholog: z2823; hypothetical protein 2024141..2026075 Escherichia coli CFT073 1036628 NP_754083.1 CDS yeaH NC_004431.1 2026188 2027471 D Escherichia coli K-12 ortholog: b1784; Escherichia coli O157:H7 ortholog: z2824; hypothetical protein 2026188..2027471 Escherichia coli CFT073 1036629 NP_754084.1 CDS yeaI NC_004431.1 2027618 2029093 D Escherichia coli K-12 ortholog: b1785; Escherichia coli O157:H7 ortholog: z2825; hypothetical protein 2027618..2029093 Escherichia coli CFT073 1036630 NP_754085.3 CDS yeaJ NC_004431.1 2029094 2030764 D Escherichia coli K-12 ortholog: b1786; Escherichia coli O157:H7 ortholog: z2826; hypothetical protein 2029094..2030764 Escherichia coli CFT073 1036631 NP_754086.1 CDS yeaK NC_004431.1 2030807 2031310 D Escherichia coli K-12 ortholog: b1787; Escherichia coli O157:H7 ortholog: z2827; hypothetical protein 2030807..2031310 Escherichia coli CFT073 1036632 NP_754087.1 CDS c2193 NC_004431.1 2031311 2031463 R Escherichia coli K-12 ortholog: b1788; Escherichia coli O157:H7 ortholog: z2828; hypothetical protein complement(2031311..2031463) Escherichia coli CFT073 1036633 NP_754088.1 CDS yeaL NC_004431.1 2031585 2032031 D Escherichia coli K-12 ortholog: b1789; Escherichia coli O157:H7 ortholog: z2829; hypothetical protein 2031585..2032031 Escherichia coli CFT073 1036635 NP_754089.1 CDS yeaM NC_004431.1 2031988 2032809 R Escherichia coli K-12 ortholog: b1790; Escherichia coli O157:H7 ortholog: z2831; transcriptional regulator YeaM complement(2031988..2032809) Escherichia coli CFT073 1036636 NP_754090.1 CDS yeaN NC_004431.1 2032906 2034087 D Escherichia coli K-12 ortholog: b1791; Escherichia coli O157:H7 ortholog: z2833; transport protein YeaN 2032906..2034087 Escherichia coli CFT073 1036637 NP_754091.3 CDS yeaO NC_004431.1 2034121 2034489 D Escherichia coli K-12 ortholog: b1792; Escherichia coli O157:H7 ortholog: z2834; hypothetical protein 2034121..2034489 Escherichia coli CFT073 1036638 NP_754092.1 CDS yoaF NC_004431.1 2034511 2034765 R Escherichia coli K-12 ortholog: b1793; Escherichia coli O157:H7 ortholog: z2835; hypothetical protein complement(2034511..2034765) Escherichia coli CFT073 1036641 NP_754093.1 CDS yeaP NC_004431.1 2034819 2035973 D Escherichia coli K-12 ortholog: b1794; Escherichia coli O157:H7 ortholog: z2836; hypothetical protein 2034819..2035973 Escherichia coli CFT073 1036642 NP_754094.1 CDS yeaQ NC_004431.1 2036241 2036489 R Escherichia coli K-12 ortholog: b1795; Escherichia coli O157:H7 ortholog: z2837; hypothetical protein complement(2036241..2036489) Escherichia coli CFT073 1036643 NP_754095.1 CDS c2201 NC_004431.1 2036501 2036623 R hypothetical protein complement(2036501..2036623) Escherichia coli CFT073 1036644 NP_754096.1 CDS yoaG NC_004431.1 2036637 2036819 R Escherichia coli K-12 ortholog: b1796; Escherichia coli O157:H7 ortholog: z2838; hypothetical protein complement(2036637..2036819) Escherichia coli CFT073 1036645 NP_754097.1 CDS c2203 NC_004431.1 2036655 2037146 D hypothetical protein 2036655..2037146 Escherichia coli CFT073 1036646 NP_754098.1 CDS yeaR NC_004431.1 2036823 2037182 R Escherichia coli K-12 ortholog: b1797; Escherichia coli O157:H7 ortholog: z2839; hypothetical protein complement(2036823..2037182) Escherichia coli CFT073 1036647 NP_754099.1 CDS yeaS NC_004431.1 2037355 2037993 R Escherichia coli K-12 ortholog: b1798; Escherichia coli O157:H7 ortholog: z2841; leucine export protein LeuE complement(2037355..2037993) Escherichia coli CFT073 1036648 NP_754100.1 CDS c2206 NC_004431.1 2038120 2038452 R Residues 56 to 110 of 110 are 94.54 pct identical to residues 260 to 314 of 314 from GenPept.129 : >gb|AAG56788.1|AE005402_14 (AE005402) transcriptional regulator LYSR-type [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(2038120..2038452) Escherichia coli CFT073 1036649 NP_754101.1 CDS c2207 NC_004431.1 2038276 2038446 D Residues 5 to 56 of 56 are 92.30 pct identical to residues 121 to 172 of 361 from GenPept.129 : >gb|AAG56789.1|AE005402_15 (AE005402) tartrate dehydrogenase [Escherichia coli O157:H7 EDL933]; hypothetical protein 2038276..2038446 Escherichia coli CFT073 1036651 NP_754102.1 CDS rnd NC_004431.1 2038536 2039663 R Escherichia coli K-12 ortholog: b1804; Escherichia coli O157:H7 ortholog: z2847; ribonuclease D complement(2038536..2039663) Escherichia coli CFT073 1036652 NP_754103.1 CDS fadD NC_004431.1 2039733 2041484 R Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(2039733..2041484) Escherichia coli CFT073 1036653 NP_754104.1 CDS yeaY NC_004431.1 2041623 2042204 R Escherichia coli K-12 ortholog: b1806; Escherichia coli O157:H7 ortholog: z2849; lipoprotein yeaY complement(2041623..2042204) Escherichia coli CFT073 1036656 NP_754105.1 CDS yeaZ NC_004431.1 2042244 2042939 R Escherichia coli K-12 ortholog: b1807; Escherichia coli O157:H7 ortholog: z2850; hypothetical protein complement(2042244..2042939) Escherichia coli CFT073 1036657 NP_754106.1 CDS c2212 NC_004431.1 2042997 2044907 R Escherichia coli K-12 ortholog: b1808; Escherichia coli O157:H7 ortholog: z2851; ATP-dependent helicase yoaA complement(2042997..2044907) Escherichia coli CFT073 1036659 NP_754107.1 CDS yoaB NC_004431.1 2044991 2045383 D Escherichia coli K-12 ortholog: b1809; Escherichia coli O157:H7 ortholog: z2852; hypothetical protein 2044991..2045383 Escherichia coli CFT073 1036666 NP_754108.1 CDS yoaC NC_004431.1 2045745 2046104 D Escherichia coli K-12 ortholog: b1810; Escherichia coli O157:H7 ortholog: z2853; hypothetical protein 2045745..2046104 Escherichia coli CFT073 1036668 NP_754109.1 CDS c2215 NC_004431.1 2046221 2046385 D hypothetical protein 2046221..2046385 Escherichia coli CFT073 1036669 NP_754110.1 CDS yoaH NC_004431.1 2046224 2046403 R Escherichia coli K-12 ortholog: b1811; Escherichia coli O157:H7 ortholog: z2854; hypothetical protein complement(2046224..2046403) Escherichia coli CFT073 1036677 NP_754111.1 CDS pabB NC_004431.1 2046477 2047838 D catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine; para-aminobenzoate synthase component I 2046477..2047838 Escherichia coli CFT073 1036679 NP_754112.1 CDS yeaB NC_004431.1 2047842 2048420 D Escherichia coli K-12 ortholog: b1813; Escherichia coli O157:H7 ortholog: z2856; hypothetical protein 2047842..2048420 Escherichia coli CFT073 1036681 NP_754113.1 CDS sdaA NC_004431.1 2048604 2049968 D Escherichia coli K-12 ortholog: b1814; Escherichia coli O157:H7 ortholog: z2857; L-serine dehydratase 1 2048604..2049968 Escherichia coli CFT073 1036688 NP_754114.1 CDS c2220 NC_004431.1 2049996 2050124 D hypothetical protein 2049996..2050124 Escherichia coli CFT073 1036694 NP_754115.1 CDS yoaD NC_004431.1 2050069 2051697 D Escherichia coli K-12 ortholog: b1815; Escherichia coli O157:H7 ortholog: z2858; hypothetical protein 2050069..2051697 Escherichia coli CFT073 1036695 NP_754116.1 CDS yoaE NC_004431.1 2051701 2053257 R Escherichia coli K-12 ortholog: b1816; Escherichia coli O157:H7 ortholog: z2859; hypothetical protein complement(2051701..2053257) Escherichia coli CFT073 1036699 NP_754117.1 CDS manX NC_004431.1 2053720 2054691 D EIIAB-Man; Escherichia coli K-12 ortholog: b1817; Escherichia coli O157:H7 ortholog: z2860; PTS system, mannose-specific IIAB component 2053720..2054691 Escherichia coli CFT073 1036702 NP_754118.1 CDS manY NC_004431.1 2054754 2055554 D EIIC-Man; Escherichia coli K-12 ortholog: b1818; Escherichia coli O157:H7 ortholog: z2861; PTS system, mannose-specific IIC component 2054754..2055554 Escherichia coli CFT073 1036703 NP_754119.1 CDS c2225 NC_004431.1 2054850 2055611 R hypothetical protein complement(2054850..2055611) Escherichia coli CFT073 1036704 NP_754120.1 CDS manZ NC_004431.1 2055558 2056418 D hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 2055558..2056418 Escherichia coli CFT073 1036705 NP_754121.1 CDS yobD NC_004431.1 2056473 2056931 D Escherichia coli K-12 ortholog: b1820; Escherichia coli O157:H7 ortholog: z2863; hypothetical protein 2056473..2056931 Escherichia coli CFT073 1036706 NP_754122.1 CDS yebN NC_004431.1 2057306 2057926 D membrane protein YebN; hypothetical protein 2057306..2057926 Escherichia coli CFT073 1036710 NP_754123.1 CDS rrmA NC_004431.1 2057923 2058732 R methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase complement(2057923..2058732) Escherichia coli CFT073 1036714 NP_754124.1 CDS c2230 NC_004431.1 2058862 2059149 D hypothetical protein 2058862..2059149 Escherichia coli CFT073 1036717 NP_754125.1 CDS cspC NC_004431.1 2058898 2059107 R CSP-C; Escherichia coli K-12 ortholog: b1823; Escherichia coli O157:H7 ortholog: z2868; cold shock-like protein CspC complement(2058898..2059107) Escherichia coli CFT073 1036718 NP_754126.1 CDS yobF NC_004431.1 2059120 2059263 R Escherichia coli K-12 ortholog: b1824; Escherichia coli O157:H7 ortholog: z2869; hypothetical protein complement(2059120..2059263) Escherichia coli CFT073 1036721 NP_754127.1 CDS yebO NC_004431.1 2059933 2060220 R Escherichia coli K-12 ortholog: b1825; Escherichia coli O157:H7 ortholog: z2871; hypothetical protein complement(2059933..2060220) Escherichia coli CFT073 1036728 NP_754128.1 CDS yobG NC_004431.1 2060295 2060438 R Escherichia coli K-12 ortholog: b1826; Escherichia coli O157:H7 ortholog: z2872; hypothetical protein complement(2060295..2060438) Escherichia coli CFT073 1036740 NP_754129.1 CDS c2235 NC_004431.1 2060597 2060836 D Escherichia coli O157:H7 ortholog: z2873; hypothetical protein 2060597..2060836 Escherichia coli CFT073 1036748 NP_754130.1 CDS c2236 NC_004431.1 2060980 2061771 R Escherichia coli K-12 ortholog: b1827; Escherichia coli O157:H7 ortholog: z2874; transcriptional regulator kdgR complement(2060980..2061771) Escherichia coli CFT073 1036749 NP_754131.1 CDS yebQ NC_004431.1 2061837 2063321 D Escherichia coli K-12 ortholog: b1828; Escherichia coli O157:H7 ortholog: z2875; transport protein YebQ 2061837..2063321 Escherichia coli CFT073 1036750 NP_754132.1 CDS htpX NC_004431.1 2063367 2064248 R metalloprotease; heat shock protein HtpX complement(2063367..2064248) Escherichia coli CFT073 1036752 NP_754133.1 CDS prc NC_004431.1 2064440 2066488 R Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease complement(2064440..2066488) Escherichia coli CFT073 1036753 NP_754134.1 CDS proQ NC_004431.1 2066508 2067206 R affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector complement(2066508..2067206) Escherichia coli CFT073 1036754 NP_754135.1 CDS c2241 NC_004431.1 2067303 2067749 R Escherichia coli K-12 ortholog: b1832; Escherichia coli O157:H7 ortholog: z2879; hypothetical protein complement(2067303..2067749) Escherichia coli CFT073 1036755 NP_754136.1 CDS yebS NC_004431.1 2067863 2069218 D Escherichia coli K-12 ortholog: b1833; Escherichia coli O157:H7 ortholog: z2880; hypothetical protein 2067863..2069218 Escherichia coli CFT073 1036756 NP_754137.1 CDS yebT NC_004431.1 2069145 2071820 D Escherichia coli K-12 ortholog: b1834; Escherichia coli O157:H7 ortholog: z2881; hypothetical protein 2069145..2071820 Escherichia coli CFT073 1036758 NP_754138.1 CDS yebU NC_004431.1 2071894 2073339 D in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 2071894..2073339 Escherichia coli CFT073 1036759 NP_754139.1 CDS yebV NC_004431.1 2073442 2073693 D Escherichia coli K-12 ortholog: b1836; Escherichia coli O157:H7 ortholog: z2883; hypothetical protein 2073442..2073693 Escherichia coli CFT073 1036760 NP_754140.1 CDS yebW NC_004431.1 2073714 2073989 D Escherichia coli K-12 ortholog: b1837; Escherichia coli O157:H7 ortholog: z2884; hypothetical protein 2073714..2073989 Escherichia coli CFT073 1036764 NP_754141.1 CDS pphA NC_004431.1 2073990 2074649 R Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 complement(2073990..2074649) Escherichia coli CFT073 1036766 NP_754142.1 CDS c2248 NC_004431.1 2074871 2075023 R hypothetical protein complement(2074871..2075023) Escherichia coli CFT073 1036767 NP_754143.1 CDS yebY NC_004431.1 2075041 2075382 R Escherichia coli K-12 ortholog: b1839; Escherichia coli O157:H7 ortholog: z2887; hypothetical protein complement(2075041..2075382) Escherichia coli CFT073 1036769 NP_754144.1 CDS yebZ NC_004431.1 2075395 2076267 R Escherichia coli K-12 ortholog: b1840; Escherichia coli O157:H7 ortholog: z2888; hypothetical protein complement(2075395..2076267) Escherichia coli CFT073 1036770 NP_754145.1 CDS c2251 NC_004431.1 2076271 2076645 R Escherichia coli K-12 ortholog: b1841; Escherichia coli O157:H7 ortholog: z2889; hypothetical protein complement(2076271..2076645) Escherichia coli CFT073 1036771 NP_754146.3 CDS holE NC_004431.1 2076697 2077014 D Escherichia coli K-12 ortholog: b1842; Escherichia coli O157:H7 ortholog: z2891; DNA polymerase III subunit theta 2076697..2077014 Escherichia coli CFT073 1036772 NP_754147.1 CDS yobB NC_004431.1 2077117 2077773 D Escherichia coli K-12 ortholog: b1843; Escherichia coli O157:H7 ortholog: z2893; hypothetical protein 2077117..2077773 Escherichia coli CFT073 1036776 NP_754148.2 CDS c2254 NC_004431.1 2077797 2078459 D 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 2077797..2078459 Escherichia coli CFT073 1036778 NP_754149.1 CDS c2255 NC_004431.1 2078456 2078851 R Residues 1 to 131 of 131 are 96.94 pct identical to residues 556 to 686 of 686 from GenPept.129 : >gb|AAC74915.1| (AE000278) protease II [Escherichia coli K12]; hypothetical protein complement(2078456..2078851) Escherichia coli CFT073 1036779 NP_754150.1 CDS ptrB NC_004431.1 2078852 2080516 R Escherichia coli K-12 ortholog: b1845; Escherichia coli O157:H7 ortholog: z2896; protease II complement(2078852..2080516) Escherichia coli CFT073 1036782 NP_754151.1 CDS c2257 NC_004431.1 2080602 2081204 D hypothetical protein 2080602..2081204 Escherichia coli CFT073 1036784 NP_754152.1 CDS yebE NC_004431.1 2080725 2081384 R Escherichia coli K-12 ortholog: b1846; Escherichia coli O157:H7 ortholog: z2897; hypothetical protein complement(2080725..2081384) Escherichia coli CFT073 1036785 NP_754153.1 CDS yebF NC_004431.1 2081711 2082079 R secreted protein; unknown function; hypothetical protein complement(2081711..2082079) Escherichia coli CFT073 1036792 NP_754154.1 CDS yebG NC_004431.1 2082134 2082424 R Escherichia coli K-12 ortholog: b1848; Escherichia coli O157:H7 ortholog: z2900; DNA damage-inducible protein YebG complement(2082134..2082424) Escherichia coli CFT073 1036797 NP_754155.1 CDS eda NC_004431.1 2083792 2084433 R catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(2083792..2084433) Escherichia coli CFT073 1036805 NP_754156.2 CDS edd NC_004431.1 2084470 2086281 R catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase complement(2084470..2086281) Escherichia coli CFT073 1036806 NP_754157.1 CDS zwf NC_004431.1 2086516 2087991 R catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(2086516..2087991) Escherichia coli CFT073 1036807 NP_754158.1 CDS c2266 NC_004431.1 2088157 2088306 R hypothetical protein complement(2088157..2088306) Escherichia coli CFT073 1036810 NP_754159.1 CDS yebK NC_004431.1 2088329 2089198 D Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 2088329..2089198 Escherichia coli CFT073 1036812 NP_754160.2 CDS pykA NC_004431.1 2089326 2090768 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2089326..2090768 Escherichia coli CFT073 1036813 NP_754161.1 CDS msbB NC_004431.1 2090900 2091871 R Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase complement(2090900..2091871) Escherichia coli CFT073 1036816 NP_754162.1 CDS yebA NC_004431.1 2091990 2093312 R ORFU; Escherichia coli K-12 ortholog: b1856; Escherichia coli O157:H7 ortholog: z2908; hypothetical protein complement(2091990..2093312) Escherichia coli CFT073 1036817 NP_754163.2 CDS znuA NC_004431.1 2093328 2094260 R involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic component complement(2093328..2094260) Escherichia coli CFT073 1036822 NP_754164.1 CDS znuC NC_004431.1 2094339 2095094 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 2094339..2095094 Escherichia coli CFT073 1036825 NP_754165.1 CDS znuB NC_004431.1 2095091 2095876 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane component 2095091..2095876 Escherichia coli CFT073 1036826 NP_754166.1 CDS ruvB NC_004431.1 2096023 2097033 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(2096023..2097033) Escherichia coli CFT073 1036828 NP_754167.1 CDS ruvA NC_004431.1 2097042 2097653 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(2097042..2097653) Escherichia coli CFT073 1036829 NP_754168.2 CDS yebB NC_004431.1 2097929 2098531 D Escherichia coli K-12 ortholog: b1862; Escherichia coli O157:H7 ortholog: z2914; hypothetical protein 2097929..2098531 Escherichia coli CFT073 1036830 NP_754169.1 CDS ruvC NC_004431.1 2098533 2099057 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(2098533..2099057) Escherichia coli CFT073 1036831 NP_754170.1 CDS yebC NC_004431.1 2099089 2099829 R Escherichia coli K-12 ortholog: b1864; Escherichia coli O157:H7 ortholog: z2916; hypothetical protein complement(2099089..2099829) Escherichia coli CFT073 1036832 NP_754171.1 CDS ntpA NC_004431.1 2099858 2100301 R converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase complement(2099858..2100301) Escherichia coli CFT073 1036833 NP_754172.1 CDS aspS NC_004431.1 2100303 2102075 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(2100303..2102075) Escherichia coli CFT073 1036836 NP_754173.2 CDS yecD NC_004431.1 2102385 2102951 D Escherichia coli K-12 ortholog: b1867; Escherichia coli O157:H7 ortholog: z2920; hypothetical protein 2102385..2102951 Escherichia coli CFT073 1036839 NP_754174.1 CDS yecE NC_004431.1 2102948 2103766 D Escherichia coli K-12 ortholog: b1868; Escherichia coli O157:H7 ortholog: z2921; hypothetical protein 2102948..2103766 Escherichia coli CFT073 1036847 NP_754175.3 CDS yecN NC_004431.1 2103789 2104214 D Escherichia coli K-12 ortholog: b1869; Escherichia coli O157:H7 ortholog: z2922; hypothetical protein 2103789..2104214 Escherichia coli CFT073 1036848 NP_754176.1 CDS yecO NC_004431.1 2104255 2104998 D Escherichia coli K-12 ortholog: b1870; Escherichia coli O157:H7 ortholog: z2923; hypothetical protein 2104255..2104998 Escherichia coli CFT073 1036849 NP_754177.1 CDS yecP NC_004431.1 2104995 2105966 D Escherichia coli K-12 ortholog: b1871; Escherichia coli O157:H7 ortholog: z2924; hypothetical protein 2104995..2105966 Escherichia coli CFT073 1036852 NP_754178.1 CDS bisZ NC_004431.1 2106131 2108578 R Escherichia coli K-12 ortholog: b1872; Escherichia coli O157:H7 ortholog: z2925; trimethylamine-N-oxide reductase 2 complement(2106131..2108578) Escherichia coli CFT073 1036854 NP_754179.1 CDS yecK NC_004431.1 2108585 2109685 R Escherichia coli K-12 ortholog: b1873; Escherichia coli O157:H7 ortholog: z2926; cytochrome c-type protein torY complement(2108585..2109685) Escherichia coli CFT073 1036855 NP_754180.1 CDS c2288 NC_004431.1 2109591 2109722 R hypothetical protein complement(2109591..2109722) Escherichia coli CFT073 1036858 NP_754181.1 CDS c2289 NC_004431.1 2110073 2110819 R Residues 103 to 248 of 248 are 97.26 pct identical to residues 1 to 146 of 146 from MG1655 : b1874; copper homeostasis protein CutC complement(2110073..2110819) Escherichia coli CFT073 1036859 NP_754182.1 CDS yecM NC_004431.1 2110833 2111405 R Escherichia coli K-12 ortholog: b1875; Escherichia coli O157:H7 ortholog: z2928; hypothetical protein complement(2110833..2111405) Escherichia coli CFT073 1036864 NP_754183.1 CDS argS NC_004431.1 2111615 2113348 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2111615..2113348 Escherichia coli CFT073 1036865 NP_754184.1 CDS flhE NC_004431.1 2113401 2113793 R Escherichia coli K-12 ortholog: b1878; Escherichia coli O157:H7 ortholog: z2931; flagellar protein flhE complement(2113401..2113793) Escherichia coli CFT073 1036868 NP_754185.3 CDS flhA NC_004431.1 2113793 2115946 R membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA complement(2113793..2115946) Escherichia coli CFT073 1036871 NP_754186.1 CDS flhB NC_004431.1 2115864 2117012 R membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB complement(2115864..2117012) Escherichia coli CFT073 1036873 NP_754187.1 CDS c2295 NC_004431.1 2117045 2117191 D hypothetical protein 2117045..2117191 Escherichia coli CFT073 1036878 NP_754188.2 CDS cheZ NC_004431.1 2117221 2117865 R cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ complement(2117221..2117865) Escherichia coli CFT073 1036881 NP_754189.1 CDS cheY NC_004431.1 2117876 2118265 R chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY complement(2117876..2118265) Escherichia coli CFT073 1036883 NP_754190.1 CDS cheB NC_004431.1 2118280 2119329 R regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase complement(2118280..2119329) Escherichia coli CFT073 1036885 NP_754191.1 CDS cheR NC_004431.1 2119332 2120192 R methylates the MCP; chemotaxis methyltransferase CheR complement(2119332..2120192) Escherichia coli CFT073 1036886 NP_754192.1 CDS c2300 NC_004431.1 2120318 2120440 R Residues 2 to 34 of 40 are 93.93 pct identical to residues 1 to 33 of 535 from GenPept.129 : >gb|AAA23567.1| (M13463) sensory transducer protein [Escherichia coli]; hypothetical protein complement(2120318..2120440) Escherichia coli CFT073 1036889 NP_754193.1 CDS tar NC_004431.1 2120483 2122165 R MCP-II; Escherichia coli K-12 ortholog: b1886; Escherichia coli O157:H7 ortholog: z2940; methyl-accepting chemotaxis protein II complement(2120483..2122165) Escherichia coli CFT073 1036890 NP_754194.1 CDS cheW NC_004431.1 2122289 2122792 R Escherichia coli K-12 ortholog: b1887; Escherichia coli O157:H7 ortholog: z2941; purine-binding chemotaxis protein complement(2122289..2122792) Escherichia coli CFT073 1036897 NP_754195.1 CDS cheA NC_004431.1 2122813 2124831 R chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA complement(2122813..2124831) Escherichia coli CFT073 1036900 NP_754196.1 CDS motB NC_004431.1 2124782 2125708 R with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB complement(2124782..2125708) Escherichia coli CFT073 1036903 NP_754197.1 CDS motA NC_004431.1 2125705 2126592 R With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA complement(2125705..2126592) Escherichia coli CFT073 1036906 NP_754198.1 CDS flhC NC_004431.1 2126718 2127296 R With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC complement(2126718..2127296) Escherichia coli CFT073 1036907 YP_004853812.1 CDS c2307 NC_004431.1 2126795 2126941 R hypothetical protein complement(2126795..2126941) Escherichia coli CFT073 1036909 NP_754200.1 CDS flhD NC_004431.1 2127299 2127658 R with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD complement(2127299..2127658) Escherichia coli CFT073 1036911 NP_754201.1 CDS yecG NC_004431.1 2128429 2128857 D ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 2128429..2128857 Escherichia coli CFT073 1036912 NP_754202.1 CDS otsA NC_004431.1 2128864 2130297 R Escherichia coli K-12 ortholog: b1896; Escherichia coli O157:H7 ortholog: z2949; trehalose-6-phosphate synthase complement(2128864..2130297) Escherichia coli CFT073 1036913 NP_754203.1 CDS otsB NC_004431.1 2130263 2131120 R biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase complement(2130263..2131120) Escherichia coli CFT073 1036914 NP_754204.1 CDS araH NC_004431.1 2131230 2132219 R Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease complement(2131230..2132219) Escherichia coli CFT073 1036915 NP_754205.2 CDS araG NC_004431.1 2132231 2133745 R Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein complement(2132231..2133745) Escherichia coli CFT073 1036917 NP_754206.1 CDS araF NC_004431.1 2133815 2134855 R ABP; Escherichia coli K-12 ortholog: b1901; Escherichia coli O157:H7 ortholog: z2954; L-arabinose-binding periplasmic protein complement(2133815..2134855) Escherichia coli CFT073 1036918 NP_754207.1 CDS yecI NC_004431.1 2135601 2136104 D Escherichia coli K-12 ortholog: b1902; Escherichia coli O157:H7 ortholog: z2956; ferritin 2135601..2136104 Escherichia coli CFT073 1036921 NP_754208.1 CDS c2316 NC_004431.1 2136183 2136434 R Residues 1 to 83 of 83 are 100.00 pct identical to residues 1 to 83 of 83 from SwissProt.40 : >sp|P52092|YECJ_ECOLI Hypothetical protein yecJ; hypothetical protein complement(2136183..2136434) Escherichia coli CFT073 1036925 NP_754209.1 CDS c2317 NC_004431.1 2136546 2136692 D hypothetical protein 2136546..2136692 Escherichia coli CFT073 1036929 NP_754210.1 CDS c2318 NC_004431.1 2136549 2136695 R hypothetical protein complement(2136549..2136695) Escherichia coli CFT073 1036930 NP_754211.1 CDS yecR NC_004431.1 2136898 2137221 D Escherichia coli K-12 ortholog: b1904; Escherichia coli O157:H7 ortholog: z2959; hypothetical protein 2136898..2137221 Escherichia coli CFT073 1036931 NP_754212.1 CDS c2320 NC_004431.1 2137231 2137368 R hypothetical protein complement(2137231..2137368) Escherichia coli CFT073 1036932 NP_754213.1 CDS ftn NC_004431.1 2137378 2137890 D cytoplasmic iron storage protein; ferritin 2137378..2137890 Escherichia coli CFT073 1036934 NP_754214.1 CDS yecH NC_004431.1 2137928 2138167 R Escherichia coli K-12 ortholog: b1906; Escherichia coli O157:H7 ortholog: z2962; hypothetical protein complement(2137928..2138167) Escherichia coli CFT073 1036936 NP_754215.1 CDS tyrP NC_004431.1 2138358 2139569 D Tyrosine permease; Escherichia coli K-12 ortholog: b1907; Escherichia coli O157:H7 ortholog: z2963; tyrosine transporter 2138358..2139569 Escherichia coli CFT073 1036938 NP_754216.1 CDS yecA NC_004431.1 2139631 2140296 R Escherichia coli K-12 ortholog: b1908; Escherichia coli O157:H7 ortholog: z2964; hypothetical protein complement(2139631..2140296) Escherichia coli CFT073 1036940 NP_754217.1 CDS pgsA NC_004431.1 2140945 2141493 R Escherichia coli K-12 ortholog: b1912; Escherichia coli O157:H7 ortholog: z3000; phosphatidylglycerophosphate synthetase complement(2140945..2141493) Escherichia coli CFT073 1036953 NP_754218.1 CDS uvrC NC_004431.1 2141550 2143382 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(2141550..2143382) Escherichia coli CFT073 1036954 NP_754219.1 CDS uvrY NC_004431.1 2143379 2144035 R in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator complement(2143379..2144035) Escherichia coli CFT073 1036955 NP_754220.1 CDS c2328 NC_004431.1 2144274 2144402 R hypothetical protein complement(2144274..2144402) Escherichia coli CFT073 1036956 NP_754221.1 CDS yecF NC_004431.1 2144494 2144718 D Escherichia coli K-12 ortholog: b1915; Escherichia coli O157:H7 ortholog: z3003; hypothetical protein 2144494..2144718 Escherichia coli CFT073 1036957 NP_754222.2 CDS sdiA NC_004431.1 2144786 2145508 R regulates genes involved in cell division; DNA-binding transcriptional activator SdiA complement(2144786..2145508) Escherichia coli CFT073 1036959 NP_754223.1 CDS yecC NC_004431.1 2145738 2146490 R Escherichia coli K-12 ortholog: b1917; Escherichia coli O157:H7 ortholog: z3005; amino-acid ABC transporter ATP-binding protein YecC complement(2145738..2146490) Escherichia coli CFT073 1036960 NP_754224.1 CDS yecS NC_004431.1 2146487 2147155 R Escherichia coli K-12 ortholog: b1918; Escherichia coli O157:H7 ortholog: z3006; amino-acid ABC transporter permease YecS complement(2146487..2147155) Escherichia coli CFT073 1036962 NP_754225.1 CDS yedO NC_004431.1 2147170 2148156 R catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase complement(2147170..2148156) Escherichia coli CFT073 1036963 NP_754226.1 CDS c2334 NC_004431.1 2148324 2148833 R Residues 18 to 169 of 169 are 94.07 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; transposase complement(2148324..2148833) Escherichia coli CFT073 1036968 NP_754227.1 CDS fliY NC_004431.1 2148973 2149830 R CBP; Escherichia coli K-12 ortholog: b1920; Escherichia coli O157:H7 ortholog: z3010; cystine transporter subunit complement(2148973..2149830) Escherichia coli CFT073 1036969 NP_754228.1 CDS fliZ NC_004431.1 2149861 2150448 R expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ complement(2149861..2150448) Escherichia coli CFT073 1036971 NP_754229.1 CDS fliA NC_004431.1 2150458 2151177 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor complement(2150458..2151177) Escherichia coli CFT073 1036974 NP_754230.1 CDS fliC NC_004431.1 2151497 2153284 R structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes; flagellin complement(2151497..2153284) Escherichia coli CFT073 1036977 NP_754231.1 CDS fliD NC_004431.1 2153550 2154956 D involved in flagellin assembly; flagellar capping protein 2153550..2154956 Escherichia coli CFT073 1036978 NP_754232.1 CDS fliS NC_004431.1 2154981 2155391 D flagellin specific chaperone; flagellar protein FliS 2154981..2155391 Escherichia coli CFT073 1036980 NP_754233.1 CDS fliT NC_004431.1 2155391 2155756 D binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 2155391..2155756 Escherichia coli CFT073 1036983 NP_754234.1 CDS amyA NC_004431.1 2155834 2157321 D converts 1,4-alpha-D-glucans to maltodextrin; cytoplasmic alpha-amylase 2155834..2157321 Escherichia coli CFT073 1036986 NP_754235.1 CDS yedD NC_004431.1 2157355 2157771 R Escherichia coli K-12 ortholog: b1928; Escherichia coli O157:H7 ortholog: z3018; hypothetical protein complement(2157355..2157771) Escherichia coli CFT073 1036991 NP_754236.1 CDS yedE NC_004431.1 2157922 2159160 D Escherichia coli K-12 ortholog: b1929; Escherichia coli O157:H7 ortholog: z3019; inner membrane protein 2157922..2159160 Escherichia coli CFT073 1036994 NP_754237.1 CDS yedF NC_004431.1 2159157 2159390 D Escherichia coli K-12 ortholog: b1930; Escherichia coli O157:H7 ortholog: z3020; hypothetical protein 2159157..2159390 Escherichia coli CFT073 1036997 NP_754238.1 CDS yedK NC_004431.1 2159499 2160167 D Escherichia coli K-12 ortholog: b1931; Escherichia coli O157:H7 ortholog: z3021; hypothetical protein 2159499..2160167 Escherichia coli CFT073 1036998 NP_754239.1 CDS c2347 NC_004431.1 2160619 2160765 D hypothetical protein 2160619..2160765 Escherichia coli CFT073 1037000 NP_754240.1 CDS c2348 NC_004431.1 2160734 2161762 D Escherichia coli K-12 ortholog: b0553; Escherichia coli O157:H7 ortholog: z2239; outer membrane porin protein nmpC 2160734..2161762 Escherichia coli CFT073 1037003 NP_754241.1 CDS ybcM NC_004431.1 2162264 2163061 R Escherichia coli K-12 ortholog: b0546; transcriptional regulator YbcM complement(2162264..2163061) Escherichia coli CFT073 1037004 NP_754242.1 CDS ybcL NC_004431.1 2163071 2163622 R DLP12 prophage; similar to PEBP/RK1P protein family in eukaryotes that inhibits MEK phosphorylation by Raf-1; crystal structure suggests similar properties but exact function is unknown; kinase inhibitor complement(2163071..2163622) Escherichia coli CFT073 1037005 NP_754243.1 CDS c2351 NC_004431.1 2163238 2163360 D hypothetical protein 2163238..2163360 Escherichia coli CFT073 1037010 NP_754244.2 CDS emrE NC_004431.1 2163791 2164123 R member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein complement(2163791..2164123) Escherichia coli CFT073 1037011 NP_754245.2 CDS fliE NC_004431.1 2164468 2164782 R forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE complement(2164468..2164782) Escherichia coli CFT073 1037015 NP_754246.1 CDS fliF NC_004431.1 2164997 2166655 D the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 2164997..2166655 Escherichia coli CFT073 1037017 NP_754247.1 CDS fliG NC_004431.1 2166648 2167643 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 2166648..2167643 Escherichia coli CFT073 1037019 NP_754248.1 CDS c2356 NC_004431.1 2166801 2167730 R hypothetical protein complement(2166801..2167730) Escherichia coli CFT073 1037021 NP_754249.2 CDS fliH NC_004431.1 2167636 2168322 D binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 2167636..2168322 Escherichia coli CFT073 1037024 NP_754250.1 CDS fliI NC_004431.1 2168322 2169695 D involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 2168322..2169695 Escherichia coli CFT073 1037026 NP_754251.1 CDS fliJ NC_004431.1 2169714 2170157 D rod/hook and filament chaperone; flagellar biosynthesis chaperone 2169714..2170157 Escherichia coli CFT073 1037027 NP_754252.1 CDS fliK NC_004431.1 2170154 2171281 D Escherichia coli K-12 ortholog: b1943; Escherichia coli O157:H7 ortholog: z3033; flagellar hook-length control protein 2170154..2171281 Escherichia coli CFT073 1037033 NP_754253.1 CDS fliL NC_004431.1 2171386 2171850 D interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body protein FliL 2171386..2171850 Escherichia coli CFT073 1037035 NP_754254.1 CDS fliM NC_004431.1 2171810 2172859 D with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 2171810..2172859 Escherichia coli CFT073 1037037 NP_754255.1 CDS fliN NC_004431.1 2172856 2173269 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 2172856..2173269 Escherichia coli CFT073 1037038 NP_754256.1 CDS fliO NC_004431.1 2173269 2173637 D with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 2173269..2173637 Escherichia coli CFT073 1037039 NP_754257.1 CDS fliP NC_004431.1 2173637 2174374 D FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 2173637..2174374 Escherichia coli CFT073 1037040 NP_754258.1 CDS fliQ NC_004431.1 2174384 2174653 D with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 2174384..2174653 Escherichia coli CFT073 1037041 NP_754259.1 CDS fliR NC_004431.1 2174662 2175447 D FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 2174662..2175447 Escherichia coli CFT073 1037042 YP_004853813.1 CDS c2368 NC_004431.1 2174685 2175083 D hypothetical protein 2174685..2175083 Escherichia coli CFT073 1037046 NP_754261.1 CDS rcsA NC_004431.1 2175737 2176360 D Escherichia coli K-12 ortholog: b1951; Escherichia coli O157:H7 ortholog: z3041; colanic acid capsular biosynthesis activation protein A 2175737..2176360 Escherichia coli CFT073 1037047 NP_754262.1 CDS dsrB NC_004431.1 2176404 2176592 R Escherichia coli K-12 ortholog: b1952; Escherichia coli O157:H7 ortholog: z3042; hypothetical protein complement(2176404..2176592) Escherichia coli CFT073 1037048 NP_754263.1 CDS c2371 NC_004431.1 2176689 2176952 R hypothetical protein complement(2176689..2176952) Escherichia coli CFT073 1037049 NP_754264.1 CDS yodD NC_004431.1 2176740 2176982 D Escherichia coli K-12 ortholog: b1953; Escherichia coli O157:H7 ortholog: z3043; hypothetical protein 2176740..2176982 Escherichia coli CFT073 1037051 NP_754265.1 CDS yedP NC_004431.1 2177280 2178095 D catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 2177280..2178095 Escherichia coli CFT073 1037052 NP_754266.1 CDS yedQ NC_004431.1 2178092 2179801 R Escherichia coli K-12 ortholog: b1956; Escherichia coli O157:H7 ortholog: z3047; hypothetical protein complement(2178092..2179801) Escherichia coli CFT073 1037057 NP_754267.1 CDS c2375 NC_004431.1 2179707 2179895 R hypothetical protein complement(2179707..2179895) Escherichia coli CFT073 1037059 NP_754268.1 CDS yodC NC_004431.1 2179957 2180139 R Escherichia coli K-12 ortholog: b1957; Escherichia coli O157:H7 ortholog: z3048; hypothetical protein complement(2179957..2180139) Escherichia coli CFT073 1037061 NP_754269.1 CDS yedI NC_004431.1 2180218 2181135 R Escherichia coli K-12 ortholog: b1958; Escherichia coli O157:H7 ortholog: z3049; hypothetical protein complement(2180218..2181135) Escherichia coli CFT073 1037063 NP_754270.1 CDS yedA NC_004431.1 2181308 2182228 D Escherichia coli K-12 ortholog: b1959; Escherichia coli O157:H7 ortholog: z3050; hypothetical protein 2181308..2182228 Escherichia coli CFT073 1037080 NP_754271.1 CDS vsr NC_004431.1 2182217 2182687 R Escherichia coli K-12 ortholog: b1960; Escherichia coli O157:H7 ortholog: z3053; very short patch repair protein complement(2182217..2182687) Escherichia coli CFT073 1037084 NP_754272.1 CDS dcm NC_004431.1 2182668 2184086 R Escherichia coli K-12 ortholog: b1961; Escherichia coli O157:H7 ortholog: z3054; DNA cytosine methylase complement(2182668..2184086) Escherichia coli CFT073 1037085 NP_754273.1 CDS yedJ NC_004431.1 2184198 2184875 R Escherichia coli K-12 ortholog: b1962; Escherichia coli O157:H7 ortholog: z3055; hypothetical protein complement(2184198..2184875) Escherichia coli CFT073 1037099 NP_754274.1 CDS yedR NC_004431.1 2184888 2185271 R Escherichia coli K-12 ortholog: b1963; Escherichia coli O157:H7 ortholog: z3056; hypothetical protein complement(2184888..2185271) Escherichia coli CFT073 1037109 NP_754275.1 CDS c2383 NC_004431.1 2185750 2186877 D Porin ompN; Escherichia coli K-12 ortholog: b1377; Escherichia coli O157:H7 ortholog: z0302; outer membrane protein N 2185750..2186877 Escherichia coli CFT073 1037128 YP_004853814.1 CDS c2384 NC_004431.1 2186327 2186551 D hypothetical protein 2186327..2186551 Escherichia coli CFT073 1037137 NP_754277.1 CDS yedU NC_004431.1 2187473 2188324 D Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 2187473..2188324 Escherichia coli CFT073 1037145 NP_754278.1 CDS yedV NC_004431.1 2188432 2189790 R Escherichia coli K-12 ortholog: b1968; Escherichia coli O157:H7 ortholog: z3060; sensor-like histidine kinase yedV complement(2188432..2189790) Escherichia coli CFT073 1037165 NP_754279.2 CDS yedW NC_004431.1 2189790 2190461 R induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW complement(2189790..2190461) Escherichia coli CFT073 1037181 NP_754280.1 CDS c2388 NC_004431.1 2190594 2191007 D Escherichia coli K-12 ortholog: b1970; Escherichia coli O157:H7 ortholog: z3062; transthyretin-like protein 2190594..2191007 Escherichia coli CFT073 1037211 NP_754281.1 CDS yedY NC_004431.1 2191116 2192120 D in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 2191116..2192120 Escherichia coli CFT073 1037215 NP_754282.1 CDS yedZ NC_004431.1 2192121 2192756 D in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 2192121..2192756 Escherichia coli CFT073 1037234 NP_754283.1 CDS yodA NC_004431.1 2193014 2193646 D Escherichia coli K-12 ortholog: b1973; Escherichia coli O157:H7 ortholog: z3065; hypothetical protein 2193014..2193646 Escherichia coli CFT073 1037244 NP_754284.1 CDS c2392 NC_004431.1 2194512 2195732 D Escherichia coli O157:H7 ortholog: z1559; P4 family integrase 2194512..2195732 Escherichia coli CFT073 1037246 NP_754285.1 CDS c2393 NC_004431.1 2195846 2197666 D Residues 9 to 606 of 606 are 31.75 pct identical to residues 13 to 622 of 624 from GenPept.129 : >gb|AAL21647.1| (AE008825) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein 2195846..2197666 Escherichia coli CFT073 1037266 NP_754286.1 CDS c2394 NC_004431.1 2197781 2199244 R Residues 5 to 407 of 487 are 26.82 pct identical to residues 6 to 347 of 417 from GenPept.129 : >dbj|BAB12639.1| (AP002527) 100 pct identical to gp:ECINCI2_2[PilV of plasmid R721]; 48 pct identical(7 gaps) to397 residues of 474 aa protein gp:D88588_18[PilV of plasmid R64] [Escherichia coli]; PilV-like protein complement(2197781..2199244) Escherichia coli CFT073 1037274 NP_754287.1 CDS c2395 NC_004431.1 2199297 2199854 R Residues 7 to 184 of 185 are 27.37 pct identical to residues 21 to 183 of 185 from GenPept.129 : >dbj|BAB12642.1| (AP002527) 30 pct identical(11 gaps) to gp:D88588_15[PilS of plasmid R64] [Escherichia coli]; type IV pilin protein complement(2199297..2199854) Escherichia coli CFT073 1037284 NP_754288.1 CDS c2396 NC_004431.1 2200253 2200567 R hypothetical protein complement(2200253..2200567) Escherichia coli CFT073 1037285 NP_754289.1 CDS c2397 NC_004431.1 2201204 2202706 D Residues 1 to 201 of 500 are 45.77 pct identical to residues 1 to 200 of 714 from GenPept.129 : >gb|AAK13432.1| (AF322908) repB/MobA-like protein [Xylella fastidiosa]; hypothetical protein 2201204..2202706 Escherichia coli CFT073 1037286 NP_754290.1 CDS c2398 NC_004431.1 2202763 2203686 D Residues 171 to 299 of 307 are 55.03 pct identical to residues 119 to 246 of 250 from GenPept.129 : >gb|AAL52855.1| (AE009602) Hypothetical Protein [Brucella melitensis]; hypothetical protein 2202763..2203686 Escherichia coli CFT073 1037287 NP_754291.1 CDS c2399 NC_004431.1 2203818 2204327 R Residues 1 to 108 of 169 are 35.19 pct identical to residues 1 to 119 of 186 from GenPept.129 : >dbj|BAB73899.1| (AP003588) ORF_ID:all2200; unknown protein [Nostoc sp. PCC 7120]; hypothetical protein complement(2203818..2204327) Escherichia coli CFT073 1037289 NP_754292.1 CDS c2400 NC_004431.1 2204464 2205300 D Residues 1 to 278 of 278 are 66.18 pct identical to residues 5 to 282 of 282 from GenPept.129 : >emb|CAD16319.1| (AL646071) HYPOTHETICAL TRANSMEMBRANE PROTEIN [Ralstonia solanacearum]; hypothetical protein 2204464..2205300 Escherichia coli CFT073 1037295 NP_754293.1 CDS c2401 NC_004431.1 2205646 2206221 R hypothetical protein complement(2205646..2206221) Escherichia coli CFT073 1037296 NP_754294.1 CDS c2402 NC_004431.1 2206262 2206399 R hypothetical protein complement(2206262..2206399) Escherichia coli CFT073 1037297 NP_754295.1 CDS c2403 NC_004431.1 2206594 2207082 D hypothetical protein 2206594..2207082 Escherichia coli CFT073 1037298 NP_754296.1 CDS c2404 NC_004431.1 2207072 2207284 D Residues 23 to 67 of 70 are 57.77 pct identical to residues 16 to 60 of 131 from GenPept.129 : >dbj|BAB36929.1| (AP002562) hypothetical lipoprotein [Escherichia coli O157:H7]; hypothetical protein 2207072..2207284 Escherichia coli CFT073 1037300 NP_754297.1 CDS c2405 NC_004431.1 2207572 2208753 R hypothetical protein complement(2207572..2208753) Escherichia coli CFT073 1037301 NP_754298.1 CDS c2406 NC_004431.1 2208805 2209767 R hypothetical protein complement(2208805..2209767) Escherichia coli CFT073 1037304 NP_754299.1 CDS c2407 NC_004431.1 2210085 2210237 D hypothetical protein 2210085..2210237 Escherichia coli CFT073 1037305 NP_754300.1 CDS c2408 NC_004431.1 2211120 2211701 D Residues 11 to 168 of 193 are 33.33 pct identical to residues 8 to 171 of 193 from GenPept.129 : >dbj|BAA92822.1| (AB022096) replication protein [Pseudoalteromonas sp. PS1M3]; hypothetical protein 2211120..2211701 Escherichia coli CFT073 1037306 NP_754301.1 CDS c2409 NC_004431.1 2211786 2212517 R hypothetical protein complement(2211786..2212517) Escherichia coli CFT073 1037307 NP_754302.1 CDS c2410 NC_004431.1 2212691 2213170 D hypothetical protein 2212691..2213170 Escherichia coli CFT073 1037309 NP_754303.1 CDS c2411 NC_004431.1 2213329 2213733 D Histone-like protein HLP-II; Escherichia coli K-12 ortholog: b1237; Escherichia coli O157:H7 ortholog: z2013; DNA-binding protein H-NS 2213329..2213733 Escherichia coli CFT073 1037311 NP_754304.1 CDS c2412 NC_004431.1 2213797 2214177 R Residues 24 to 125 of 126 are 52.94 pct identical to residues 1 to 102 of 102 from GenPept.129 : >gb|AAA23184.1| (M13819) unknown [Plasmid ColIa]; hypothetical protein complement(2213797..2214177) Escherichia coli CFT073 1037314 NP_754305.1 CDS c2413 NC_004431.1 2214256 2214498 R hypothetical protein complement(2214256..2214498) Escherichia coli CFT073 1037315 NP_754306.1 CDS c2414 NC_004431.1 2214571 2214867 R hypothetical protein complement(2214571..2214867) Escherichia coli CFT073 1037317 NP_754307.1 CDS c2415 NC_004431.1 2214920 2215222 R hypothetical protein complement(2214920..2215222) Escherichia coli CFT073 1037321 NP_754308.1 CDS c2416 NC_004431.1 2215727 2216620 R Residues 24 to 281 of 297 are 26.97 pct identical to residues 7 to 269 of 283 from GenPept.129 : >gb|AAG57759.1|AE005493_12 (AE005493) Z3947 gene product [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(2215727..2216620) Escherichia coli CFT073 1037322 NP_754309.1 CDS yeeI NC_004431.1 2216985 2217821 D Escherichia coli K-12 ortholog: b1976; Escherichia coli O157:H7 ortholog: z3132; hypothetical protein 2216985..2217821 Escherichia coli CFT073 1037325 NP_754310.1 CDS c2418 NC_004431.1 2218378 2219421 D Int(P4); Escherichia coli K-12 ortholog: b4271; Escherichia coli O157:H7 ortholog: z4313; prophage P4 integrase 2218378..2219421 Escherichia coli CFT073 1037330 NP_754311.1 CDS c2419 NC_004431.1 2219615 2220919 R catalyzes the conversion of chorismate to salicylate in the biosynthesis of the siderophore yersiniabactin; salicylate synthase Irp9 complement(2219615..2220919) Escherichia coli CFT073 1037332 NP_754312.1 CDS c2420 NC_004431.1 2220947 2222350 R Similar to YbtX [Yersinia pestis] and Irp8 [Yersinia enterocolitica]; Residues 6 to 467 of 467 are 99.35 pct identical to residues 1 to 462 of 462 from GenPept.129 : >emb|CAA21386.1| (AL031866) ORF63,len=462 aa, transmembrane protein, similarity to Escherichia coli ECAMPG3_1 E.coli ampG3 gene, 27.1% identity in 376 aa overlap, Fasta scores: opt: 311, E(): 1.1e-12 [Yersinia pestis]; cytoplasmic transmembrane protein complement(2220947..2222350) Escherichia coli CFT073 1037333 NP_754313.1 CDS c2421 NC_004431.1 2222220 2224049 R Similar to YbtQ [Yersinia pestis] and Irp7 [Yersinia enterocolitica]; Residues 10 to 609 of 609 are 99.50 pct identical to residues 1 to 600 of 600 from GenPept.129 : >emb|CAC90730.1| (AJ414150) inner membrane ABC-transporter YbtQ [Yersinia pestis]; ABC transporter complement(2222220..2224049) Escherichia coli CFT073 1037334 NP_754314.1 CDS c2422 NC_004431.1 2224009 2225811 R Similar to YbtP [Yersinia pestis] and Irp6 [Yersinia enterocolitica]; Residues 1 to 600 of 600 are 100.00 pct identical to residues 1 to 600 of 600 from GenPept.129 : >gb|AAC69585.1| (AF091251) YbtP [Yersinia pestis]; inner membrane ABC-transporter complement(2224009..2225811) Escherichia coli CFT073 1037336 NP_754315.1 CDS c2423 NC_004431.1 2225978 2226937 D Similar to YbtA, AraC type regulator [Yersinia pestis]; Residues 1 to 319 of 319 are 99.37 pct identical to residues 1 to 319 of 319 from GenPept.129 : >emb|CAC90728.1| (AJ414150) transcriptional regulator YbtA [Yersinia pestis]; AraC type regulator 2225978..2226937 Escherichia coli CFT073 1037338 NP_754316.1 CDS c2424 NC_004431.1 2227110 2231378 D Similar to middle of Ybt peptide synthetase HMWP2 [Yersinia pestis]; Residues 7 to 1418 of 1422 are 98.22 pct identical to residues 1 to 1412 of 2035 from SwissProt.40 : >sp|P48633|HMP2_YEREN High-molecular-weight protein 2 (HMWP2); peptide synthetase 2227110..2231378 Escherichia coli CFT073 1037339 NP_754317.1 CDS c2425 NC_004431.1 2231467 2231844 R Residues 2 to 125 of 125 are 93.54 pct identical to residues 29 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein complement(2231467..2231844) Escherichia coli CFT073 1037341 NP_754318.1 CDS c2426 NC_004431.1 2231817 2233946 D Similar to C-terminus of Ybt peptide synthetase HMWP2 [Yersinia pestis]; Residues 95 to 597 of 709 are 35.05 pct identical to residues 34 to 551 of 2035 from GenPept.129 : >emb|CAC90727.1| (AJ414150) yersiniabactin biosynthetic protein [Yersinia pestis]; peptide synthetase 2231817..2233946 Escherichia coli CFT073 1037342 NP_754319.1 CDS c2427 NC_004431.1 2234022 2236217 D Similar to the N-terminus of the synthetase for the yersiniabactin siderophore [Yersinia enterocolitica]; Residues 5 to 721 of 731 are 99.72 pct identical to residues 1 to 717 of 3163 from GenPept.129 : >emb|CAC90726.1| (AJ414150) yersiniabactin biosynthetic protein [Yersinia pestis]; peptide/polyketide synthetase protein 2234022..2236217 Escherichia coli CFT073 1037343 NP_754320.1 CDS c2428 NC_004431.1 2236117 2239014 D Residues 276 to 576 of 965 are 29.73 pct identical to residues 2481 to 2770 of 3163 from GenPept.129 : >emb|CAC90726.1| (AJ414150) yersiniabactin biosynthetic protein [Yersinia pestis]; hypothetical protein 2236117..2239014 Escherichia coli CFT073 1037345 NP_754321.1 CDS c2429 NC_004431.1 2238812 2243521 D Residues 887 to 1176 of 1569 are 29.73 pct identical to residues 970 to 1270 of 3163 from GenPept.129 : >emb|CAC90726.1| (AJ414150) yersiniabactin biosynthetic protein [Yersinia pestis]; hypothetical protein 2238812..2243521 Escherichia coli CFT073 1037348 NP_754322.1 CDS c2430 NC_004431.1 2243518 2244618 D Residues 1 to 366 of 366 are 99.72 pct identical to residues 1 to 366 of 366 from GenPept.129 : >emb|CAC90725.1| (AJ414150) yersiniabactin biosynthetic protein YbtU [Yersinia pestis]; hypothetical protein 2243518..2244618 Escherichia coli CFT073 1037349 NP_754323.1 CDS c2431 NC_004431.1 2244588 2244722 R hypothetical protein complement(2244588..2244722) Escherichia coli CFT073 1037381 NP_754324.1 CDS c2432 NC_004431.1 2244762 2245418 D Similar to YbtT [Yersinia pestis]; Residues 1 to 187 of 218 are 40.95 pct identical to residues 48 to 235 of 252 from SwissProt.40 : >sp|P19829|SAST_VIBAN Probable anguibactin biosynthesis thioesterase; thioesterase 2244762..2245418 Escherichia coli CFT073 1037387 NP_754325.1 CDS c2433 NC_004431.1 2245422 2246669 D Enterochelin synthase E; Escherichia coli K-12 ortholog: b0594; Escherichia coli O157:H7 ortholog: z0736; bifunctional; Enterobactin synthetase component E; S-dihydroxybenzoyltransferase; 2,3-dihydroxybenzoate-AMP ligase 2245422..2246669 Escherichia coli CFT073 1037388 NP_754326.1 CDS c2434 NC_004431.1 2246714 2246998 D Similar to ligase YbtE [Yersinia pestis]; Residues 1 to 94 of 94 are 98.93 pct identical to residues 432 to 525 of 525 from GenPept.129 : >emb|CAC90723.1| (AJ414150) yersiniabactin siderophore biosynthetic protein [Yersinia pestis]; salicyl-AMP ligase 2246714..2246998 Escherichia coli CFT073 1037395 NP_754327.1 CDS c2435 NC_004431.1 2246735 2247004 R hypothetical protein complement(2246735..2247004) Escherichia coli CFT073 1037401 NP_754328.1 CDS c2436 NC_004431.1 2247129 2249150 D Similar to FyuA precursor [Yersinia pestis]; Residues 1 to 673 of 673 are 99.85 pct identical to residues 1 to 673 of 673 from SwissProt.40 : >sp|P46359|FYUA_YERPE Pesticin receptor precursor (IRPC); pesticin receptor 2247129..2249150 Escherichia coli CFT073 1037428 NP_754329.1 CDS c2437 NC_004431.1 2249741 2250547 D Residues 14 to 136 of 268 are 98.37 pct identical to residues 2 to 124 of 128 from GenPept.129 : >gb|AAC69596.1| (AF091251) unknown [Yersinia pestis]; hypothetical protein 2249741..2250547 Escherichia coli CFT073 1037431 NP_754330.1 CDS c2438 NC_004431.1 2250474 2250644 D Residues 1 to 47 of 56 are 93.61 pct identical to residues 1459 to 1505 of 2383 from GenPept.129 : >gb|AAC75042.1| (AE000289) factor [Escherichia coli K12]; hypothetical protein 2250474..2250644 Escherichia coli CFT073 1037434 NP_754331.1 CDS c2439 NC_004431.1 2250680 2252149 D Residues 35 to 487 of 489 are 26.20 pct identical to residues 531 to 997 of 2383 from GenPept.129 : >gb|AAC75042.1| (AE000289) factor [Escherichia coli K12]; hypothetical protein 2250680..2252149 Escherichia coli CFT073 1037449 NP_754332.1 CDS c2440 NC_004431.1 2252162 2252638 D Residues 1 to 148 of 158 are 82.43 pct identical to residues 2127 to 2273 of 2383 from GenPept.129 : >gb|AAC75042.1| (AE000289) factor [Escherichia coli K12]; hypothetical protein 2252162..2252638 Escherichia coli CFT073 1037467 NP_754333.1 CDS c2441 NC_004431.1 2252766 2253386 R Residues 1 to 206 of 206 are 95.14 pct identical to residues 145 to 350 of 350 from GenPept.129 : >dbj|BAB36200.1| (AP002559) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein complement(2252766..2253386) Escherichia coli CFT073 1037496 NP_754334.1 CDS c2442 NC_004431.1 2253361 2253879 R Residues 22 to 157 of 172 are 98.52 pct identical to residues 1 to 136 of 350 from GenPept.129 : >gb|AAG57043.1|AE005424_1 (AE005424) Z3137 gene product [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(2253361..2253879) Escherichia coli CFT073 1037534 NP_754335.1 CDS shiA NC_004431.1 2254131 2255447 D Escherichia coli K-12 ortholog: b1981; Escherichia coli O157:H7 ortholog: z3138; shikimate transporter 2254131..2255447 Escherichia coli CFT073 1037558 NP_754336.2 CDS amn NC_004431.1 2255549 2257003 D Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 2255549..2257003 Escherichia coli CFT073 1037571 NP_754337.1 CDS yeeN NC_004431.1 2257346 2258062 D Escherichia coli K-12 ortholog: b1983; Escherichia coli O157:H7 ortholog: z3140; hypothetical protein 2257346..2258062 Escherichia coli CFT073 1037574 NP_754338.2 CDS nac NC_004431.1 2258918 2259835 D Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator 2258918..2259835 Escherichia coli CFT073 1037586 NP_754339.1 CDS cbl NC_004431.1 2259937 2260887 D LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl 2259937..2260887 Escherichia coli CFT073 1037592 NP_754340.1 CDS yeeO NC_004431.1 2261008 2262648 D Escherichia coli K-12 ortholog: b1985; Escherichia coli O157:H7 ortholog: z3144; hypothetical protein 2261008..2262648 Escherichia coli CFT073 1037627 NP_754341.1 CDS c2449 NC_004431.1 2262986 2264257 D Int(P4); Escherichia coli K-12 ortholog: b4271; Escherichia coli O157:H7 ortholog: z4313; prophage P4 integrase 2262986..2264257 Escherichia coli CFT073 1037632 NP_754342.1 CDS c2450 NC_004431.1 2264537 2265049 R Residues 1 to 166 of 170 are 53.61 pct identical to residues 1 to 165 of 172 from GenPept.129 : >gb|AAF60966.1|AF188737_1 (AF188737) unknown [Escherichia coli]; hypothetical protein complement(2264537..2265049) Escherichia coli CFT073 1037633 NP_754343.1 CDS c2451 NC_004431.1 2265084 2265806 R Residues 4 to 233 of 240 are 33.91 pct identical to residues 1 to 228 of 234 from GenPept.129 : >gb|AAD21211.1| (AF007865) BacT [Bacillus licheniformis]; thioesterase complement(2265084..2265806) Escherichia coli CFT073 1037635 NP_754344.1 CDS c2452 NC_004431.1 2265799 2267313 R Residues 41 to 499 of 504 are 27.77 pct identical to residues 41 to 494 of 498 from GenPept.129 : >dbj|BAB58603.1| (AP003365) hypothetical protein [Staphylococcus aureus subsp. aureus Mu50]; hypothetical protein complement(2265799..2267313) Escherichia coli CFT073 1037636 NP_754345.1 CDS c2453 NC_004431.1 2267326 2269785 R polyketide synthase; Residues 13 to 647 of 819 are 36.74 pct identical to residues 1458 to 2126 of 3291 from GenPept.129 : >gb|AAF19812.1|AF188287_4 (AF188287) MtaD [Stigmatella aurantiaca]; polyketide synthase complement(2267326..2269785) Escherichia coli CFT073 1037638 NP_754346.1 CDS c2454 NC_004431.1 2269816 2270931 R Residues 47 to 278 of 371 are 30.20 pct identical to residues 1809 to 2049 of 2157 from GenPept.129 : >gb|AAL44495.1| (AE009298) peptide synthetase [Agrobacterium tumefaciens str. C58 (U. Washington)]; hypothetical protein complement(2269816..2270931) Escherichia coli CFT073 1037644 NP_754347.1 CDS c2455 NC_004431.1 2270909 2274271 R peptide synthetase; Residues 35 to 363 of 1120 are 22.25 pct identical to residues 4932 to 5253 of 5369 from GenPept.129 : >gb|AAF08796.1|AF184956_3 (AF184956) MycB [Bacillus subtilis]; peptide synthetase complement(2270909..2274271) Escherichia coli CFT073 1037646 NP_754348.1 CDS c2456 NC_004431.1 2274181 2275620 R Residues 26 to 457 of 479 are 29.47 pct identical to residues 14 to 449 of 461 from GenPept.129 : >gb|AAL80832.1| (AE010190) hypothetical protein [Pyrococcus furiosus DSM 3638]; hypothetical protein complement(2274181..2275620) Escherichia coli CFT073 1037656 NP_754349.1 CDS c2457 NC_004431.1 2275682 2277169 R Residues 17 to 492 of 495 are 35.31 pct identical to residues 12 to 484 of 507 from GenPept.129 : >gb|AAG30199.1| (AF293442) enantiomer selective amidase [Streptomyces sp. R1128]; amidase complement(2275682..2277169) Escherichia coli CFT073 1037661 NP_754350.1 CDS c2458 NC_004431.1 2277138 2283602 R Residues 1988 to 2110 of 2154 are 33.33 pct identical to residues 947 to 1067 of 2459 from GenPept.129 : >dbj|BAB74344.1| (AP003590) peptide synthetase [Nostoc sp. PCC 7120]; peptide synthetase complement(2277138..2283602) Escherichia coli CFT073 1037664 NP_754351.1 CDS c2459 NC_004431.1 2283613 2290113 R Residues 1998 to 2132 of 2166 are 30.37 pct identical to residues 2271 to 2401 of 2459 from GenPept.129 : >dbj|BAB74344.1| (AP003590) peptide synthetase [Nostoc sp. PCC 7120]; peptide synthetase complement(2283613..2290113) Escherichia coli CFT073 1037665 NP_754352.1 CDS c2460 NC_004431.1 2290157 2293189 R Residues 4 to 882 of 1010 are 46.58 pct identical to residues 8 to 898 of 1244 from GenPept.129 : >gb|AAF15892.2|AF204805_2 (AF204805) NosB [Nostoc sp. GSV224]; polyketide synthase complement(2290157..2293189) Escherichia coli CFT073 1037666 NP_754353.1 CDS c2461 NC_004431.1 2293239 2298050 R Residues 46 to 514 of 1603 are 34.82 pct identical to residues 2731 to 3210 of 3317 from GenPept.129 : >gb|AAF17280.1| (AF204805) NosC [Nostoc sp. GSV224]; hypothetical protein complement(2293239..2298050) Escherichia coli CFT073 1037668 NP_754354.1 CDS c2462 NC_004431.1 2295405 2295536 D hypothetical protein 2295405..2295536 Escherichia coli CFT073 1037673 NP_754355.1 CDS c2463 NC_004431.1 2298083 2299351 R Residues 4 to 392 of 422 are 29.30 pct identical to residues 3 to 374 of 400 from GenPept.129 : >dbj|BAB69697.1| (AB050629) malonyl-CoA transacylase [Bacillus subtilis]; transacylase complement(2298083..2299351) Escherichia coli CFT073 1037674 NP_754356.1 CDS c2464 NC_004431.1 2299348 2300376 R Residues 3 to 335 of 342 are 35.02 pct identical to residues 35 to 368 of 382 from GenPept.129 : >gb|AAD40109.1|AF155831_3 (AF155831) unknown [Bacillus cereus]; acyl-coa dehydrogenase complement(2299348..2300376) Escherichia coli CFT073 1037678 NP_754357.1 CDS c2465 NC_004431.1 2300422 2300619 D hypothetical protein 2300422..2300619 Escherichia coli CFT073 1037692 NP_754358.1 CDS c2466 NC_004431.1 2300482 2300730 R Residues 1 to 78 of 82 are 30.76 pct identical to residues 1 to 77 of 81 from GenPept.129 : >gb|AAL32271.1| (AF235003) D-alanyl carrier protein [Bacillus thuringiensis serovar kurstaki]; hypothetical protein complement(2300482..2300730) Escherichia coli CFT073 1037695 NP_754359.1 CDS c2467 NC_004431.1 2300760 2301629 R Residues 2 to 282 of 289 are 45.55 pct identical to residues 1 to 278 of 278 from SwissProt.40 : >sp|Q9RVG1|HBD_DEIRA Probable 3-hydroxybutyryl-CoA dehydrogenase (Beta-hydroxybutyryl-CoA dehydrogenase) (BHBD); 3-hydroxyacyl-CoA dehydrogenase complement(2300760..2301629) Escherichia coli CFT073 1037697 NP_754360.1 CDS c2468 NC_004431.1 2301639 2304248 R Residues 15 to 504 of 869 are 46.97 pct identical to residues 1458 to 1953 of 3291 from GenPept.129 : >gb|AAF19812.1|AF188287_4 (AF188287) MtaD [Stigmatella aurantiaca]; polyketide synthase complement(2301639..2304248) Escherichia coli CFT073 1037698 NP_754361.1 CDS c2469 NC_004431.1 2304280 2308338 R Residues 34 to 562 of 1352 are 24.60 pct identical to residues 2344 to 2882 of 7257 from GenPept.129 : >gb|AAF62883.1|AF217189_6 (AF217189) epoD [Polyangium cellulosum]; polyketide synthase complement(2304280..2308338) Escherichia coli CFT073 1037706 NP_754362.1 CDS c2470 NC_004431.1 2308283 2313910 R Residues 527 to 1874 of 1875 are 32.28 pct identical to residues 47 to 1483 of 2632 from GenPept.129 : >dbj|BAB12213.1| (AB032549) peptide synthetase and polyketide synthase [Microcystis aeruginosa]; peptide/polyketide synthase complement(2308283..2313910) Escherichia coli CFT073 1037707 NP_754363.1 CDS c2471 NC_004431.1 2314524 2315258 D Residues 22 to 171 of 244 are 38.41 pct identical to residues 32 to 178 of 249 from GenPept.129 : >gb|AAD10395.1| (U46488) NrpG [Proteus mirabilis]; hypothetical protein 2314524..2315258 Escherichia coli CFT073 1037708 NP_754364.1 CDS c2472 NC_004431.1 2315404 2315670 D Residues 1 to 88 of 88 are 71.59 pct identical to residues 1 to 88 of 88 from SwissProt.40 : >sp|Q00931|LCRS_YERPE Low calcium response locus protein S; transposase 2315404..2315670 Escherichia coli CFT073 1037712 NP_754365.1 CDS c2473 NC_004431.1 2315775 2316254 D Residues 3 to 148 of 159 are 46.57 pct identical to residues 24 to 169 of 183 from SwissProt.40 : >sp|P24577|YI71_BURCE INSERTION ELEMENT IS407 HYPOTHETICAL 20.5 KD PROTEIN (ORF1); transposase 2315775..2316254 Escherichia coli CFT073 1037713 NP_754366.1 CDS c2474 NC_004431.1 2316245 2316472 D Residues 3 to 75 of 75 are 85.00 pct identical to residues 115 to 194 of 194 from GenPept.129 : >gb|AAL72372.1| (AF386526) transposase [Shigella flexneri 2a]; transposase 2316245..2316472 Escherichia coli CFT073 1037714 NP_754367.1 CDS c2475 NC_004431.1 2316562 2316987 R hypothetical protein complement(2316562..2316987) Escherichia coli CFT073 1037717 NP_754368.1 CDS erfK NC_004431.1 2317279 2318214 R Escherichia coli K-12 ortholog: b1990; Escherichia coli O157:H7 ortholog: z3150; hypothetical protein complement(2317279..2318214) Escherichia coli CFT073 1037719 NP_754369.1 CDS cobT NC_004431.1 2318276 2319355 R catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase complement(2318276..2319355) Escherichia coli CFT073 1037722 NP_754370.1 CDS cobS NC_004431.1 2319367 2320146 R catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase complement(2319367..2320146) Escherichia coli CFT073 1037726 NP_754371.1 CDS cobU NC_004431.1 2320107 2320652 R catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase complement(2320107..2320652) Escherichia coli CFT073 1037729 NP_754372.1 CDS c2480 NC_004431.1 2320804 2320926 R hypothetical protein complement(2320804..2320926) Escherichia coli CFT073 1037730 NP_754373.1 CDS c2481 NC_004431.1 2321117 2321281 R hypothetical protein complement(2321117..2321281) Escherichia coli CFT073 1037731 NP_754374.1 CDS c2482 NC_004431.1 2322324 2324471 D Escherichia coli O157:H7 ortholog: z3159; outer membrane receptor for iron compound or colicin 2322324..2324471 Escherichia coli CFT073 1037732 NP_754375.1 CDS c2483 NC_004431.1 2324459 2324587 D hypothetical protein 2324459..2324587 Escherichia coli CFT073 1037733 NP_754376.1 CDS c2484 NC_004431.1 2324842 2325486 R Escherichia coli K-12 ortholog: b0601; Escherichia coli O157:H7 ortholog: z1644; hypothetical protein complement(2324842..2325486) Escherichia coli CFT073 1037734 NP_754377.1 CDS c2485 NC_004431.1 2325471 2326760 R Escherichia coli K-12 ortholog: b0602; Escherichia coli O157:H7 ortholog: z1643; hypothetical protein complement(2325471..2326760) Escherichia coli CFT073 1037736 NP_754378.1 CDS c2486 NC_004431.1 2327685 2328395 D Residues 17 to 198 of 236 are 64.86 pct identical to residues 1 to 185 of 185 from SwissProt.40 : >sp|P71311|YAIS_ECOLI HYPOTHETICAL 20.5 KDA PROTEIN IN ADHC-TAUA INTERGENIC REGION; hypothetical protein 2327685..2328395 Escherichia coli CFT073 1037737 NP_754379.1 CDS c2489 NC_004431.1 2329640 2330164 D Escherichia coli K-12 ortholog: b0359; transferase 2329640..2330164 Escherichia coli CFT073 1037739 NP_754380.1 CDS c2490 NC_004431.1 2330118 2330939 D Escherichia coli K-12 ortholog: b0358; hypothetical protein 2330118..2330939 Escherichia coli CFT073 1037740 NP_754381.1 CDS c2492 NC_004431.1 2331944 2333158 D Residues 1 to 404 of 404 are 80.69 pct identical to residues 1 to 404 of 404 from GenPept.129 : >gb|AAL22407.1| (AE008863) transcriptional regulator of sugar metabolism [Salmonella typhimurium LT2]; carbohydrate kinase 2331944..2333158 Escherichia coli CFT073 1037744 NP_754382.1 CDS c2493 NC_004431.1 2333172 2333930 D Residues 1 to 252 of 252 are 81.74 pct identical to residues 1 to 252 of 253 from GenPept.129 : >gb|AAL22408.1| (AE008863) cytoplasmic protein [Salmonella typhimurium LT2]; hypothetical protein 2333172..2333930 Escherichia coli CFT073 1037745 NP_754383.1 CDS c2494 NC_004431.1 2333984 2334949 D Residues 1 to 321 of 321 are 93.76 pct identical to residues 1 to 321 of 323 from GenPept.129 : >emb|CAD08080.1| (AL627281) membrane protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein 2333984..2334949 Escherichia coli CFT073 1037748 NP_754384.1 CDS c2495 NC_004431.1 2334952 2335986 D Residues 1 to 344 of 344 are 86.62 pct identical to residues 1 to 344 of 344 from GenPept.129 : >gb|AAL22410.1| (AE008863) phosphotriesterase [Salmonella typhimurium LT2]; phosphotriesterase-related protein 2334952..2335986 Escherichia coli CFT073 1037749 NP_754385.1 CDS c2496 NC_004431.1 2336398 2336559 R Residues 1 to 53 of 53 are 94.33 pct identical to residues 487 to 539 of 539 from GenPept.129 : >gb|AAL57569.1|AF453441_53 (AF453441) transposase [Escherichia coli]; hypothetical protein complement(2336398..2336559) Escherichia coli CFT073 1037752 NP_754386.1 CDS c2497 NC_004431.1 2336638 2337495 R Residues 2 to 285 of 285 are 92.25 pct identical to residues 176 to 459 of 539 from GenPept.129 : >gb|AAL57569.1|AF453441_53 (AF453441) transposase [Escherichia coli]; transposase complement(2336638..2337495) Escherichia coli CFT073 1037754 NP_754387.1 CDS c2498 NC_004431.1 2338301 2338711 R Residues 1 to 129 of 136 are 97.67 pct identical to residues 30 to 158 of 173 from GenPept.129 : >gb|AAL08463.1|AF326777_38 (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein complement(2338301..2338711) Escherichia coli CFT073 1037758 NP_754388.1 CDS c2499 NC_004431.1 2338699 2339100 R Residues 1 to 121 of 133 are 87.60 pct identical to residues 1 to 121 of 127 from GenPept.129 : >gb|AAK00467.1| (AF200692) unknown [Shigella flexneri 2a]; hypothetical protein complement(2338699..2339100) Escherichia coli CFT073 1037759 NP_754389.1 CDS c2500 NC_004431.1 2339266 2339871 R Residues 17 to 201 of 201 are 40.43 pct identical to residues 6 to 235 of 246 from GenPept.129 : >gb|AAL67401.1|AF447814_69 (AF447814) intergenic-region protein [Escherichia coli]; hypothetical protein complement(2339266..2339871) Escherichia coli CFT073 1037761 NP_754390.1 CDS c2501 NC_004431.1 2340476 2340652 R Residues 1 to 43 of 58 are 97.67 pct identical to residues 1 to 43 of 58 from GenPept.129 : >gb|AAL08465.1|AF326777_40 (AF326777) transcriptional regulator [Shigella flexneri 2a]; hypothetical protein complement(2340476..2340652) Escherichia coli CFT073 1037762 NP_754391.1 CDS c2502 NC_004431.1 2340603 2340983 D hypothetical protein 2340603..2340983 Escherichia coli CFT073 1037763 NP_754392.1 CDS c2503 NC_004431.1 2341416 2342612 D Residues 6 to 393 of 398 are 58.82 pct identical to residues 3 to 393 of 405 from SwissProt.40 : >sp|P19780|YIS1_STRCO Insertion element IS110 hypothetical 43.6 kDa protein; transposase 2341416..2342612 Escherichia coli CFT073 1037764 NP_754393.1 CDS c2504 NC_004431.1 2342382 2342519 R hypothetical protein complement(2342382..2342519) Escherichia coli CFT073 1037765 NP_754394.1 CDS c2505 NC_004431.1 2342736 2343014 D Residues 1 to 92 of 92 are 93.47 pct identical to residues 1 to 92 of 92 from GenPept.129 : >gb|AAL08466.1| (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 2342736..2343014 Escherichia coli CFT073 1037766 NP_754395.1 CDS c2506 NC_004431.1 2343093 2343332 D Residues 4 to 78 of 79 are 97.33 pct identical to residues 1 to 75 of 202 from GenPept.129 : >gb|AAL08467.1| (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 2343093..2343332 Escherichia coli CFT073 1037767 NP_754396.1 CDS c2508 NC_004431.1 2344396 2344920 D Residues 1 to 174 of 174 are 99.42 pct identical to residues 315 to 488 of 488 from GenPept.129 : >gb|AAL67386.1|AF447814_54 (AF447814) R6-like protein [Escherichia coli]; hypothetical protein 2344396..2344920 Escherichia coli CFT073 1037768 NP_754397.1 CDS c2509 NC_004431.1 2344917 2345672 D Residues 1 to 244 of 251 are 41.60 pct identical to residues 1 to 250 of 298 from SwissProt.40 : >sp|P55500|Y4IQ_RHISN INSERTION SEQUENCE ATP-BINDING PROTEIN Y4IQ/Y4ND/Y4SD; insertion sequence ATP-binding protein 2344917..2345672 Escherichia coli CFT073 1037769 NP_754398.1 CDS c2510 NC_004431.1 2345772 2346125 D Residues 1 to 113 of 117 are 84.95 pct identical to residues 86 to 198 of 202 from GenPept.129 : >gb|AAL08467.1| (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 2345772..2346125 Escherichia coli CFT073 1037770 NP_754399.1 CDS c2511 NC_004431.1 2347151 2347933 R Residues 10 to 256 of 260 are 46.96 pct identical to residues 4 to 248 of 265 from SwissProt.40 : >sp|P15026|ISTB_PSEAE Insertion sequence IS21 ATP-binding protein; transposase/IS protein complement(2347151..2347933) Escherichia coli CFT073 1037774 NP_754400.1 CDS c2512 NC_004431.1 2347930 2348952 R Residues 1 to 340 of 340 are 99.70 pct identical to residues 1 to 340 of 340 from GenPept.129 : >emb|CAC43410.1| (X16664) Y1093 protein [Escherichia coli]; transposase complement(2347930..2348952) Escherichia coli CFT073 1037776 NP_754401.1 CDS c2513 NC_004431.1 2349503 2349880 R hypothetical protein complement(2349503..2349880) Escherichia coli CFT073 1037778 NP_754402.1 CDS c2514 NC_004431.1 2350449 2351621 D hypothetical protein 2350449..2351621 Escherichia coli CFT073 1037780 NP_754403.1 CDS c2515 NC_004431.1 2352463 2353230 R Residues 1 to 255 of 255 are 100.00 pct identical to residues 1 to 255 of 255 from GenPept.129 : >gb|AAL67370.1|AF447814_38 (AF447814) ferric-enterobactin-transport protein [Escherichia coli]; ABC transporter complement(2352463..2353230) Escherichia coli CFT073 1037781 NP_754404.1 CDS c2516 NC_004431.1 2353227 2354285 R Residues 1 to 352 of 352 are 100.00 pct identical to residues 1 to 352 of 352 from GenPept.129 : >gb|AAL67369.1|AF447814_37 (AF447814) permease [Escherichia coli]; ABC transporter complement(2353227..2354285) Escherichia coli CFT073 1037782 NP_754405.1 CDS c2517 NC_004431.1 2354304 2355296 R Residues 1 to 330 of 330 are 99.39 pct identical to residues 1 to 332 of 332 from GenPept.129 : >gb|AAL67368.1|AF447814_36 (AF447814) iron-chelating periplasmic-binding protein [Escherichia coli]; periplasmic binding protein complement(2354304..2355296) Escherichia coli CFT073 1037783 NP_754406.1 CDS c2518 NC_004431.1 2355304 2357469 R Residues 1 to 530 of 721 are 100.00 pct identical to residues 1 to 530 of 536 from GenPept.129 : >gb|AAL67366.1|AF447814_34 (AF447814) truncated ferric siderophore receptor [Escherichia coli]; TonB dependent receptor complement(2355304..2357469) Escherichia coli CFT073 1037784 NP_754407.1 CDS c2520 NC_004431.1 2358550 2360934 D Escherichia coli O157:H7 ortholog: z1652; hypothetical protein 2358550..2360934 Escherichia coli CFT073 1037786 NP_754408.1 CDS c2521 NC_004431.1 2360110 2360286 R hypothetical protein complement(2360110..2360286) Escherichia coli CFT073 1037787 NP_754409.1 CDS c2522 NC_004431.1 2360931 2361836 D Escherichia coli O157:H7 ortholog: z1653; hypothetical protein 2360931..2361836 Escherichia coli CFT073 1037788 NP_754410.1 CDS c2523 NC_004431.1 2361833 2362903 D Escherichia coli O157:H7 ortholog: z1654; hypothetical protein 2361833..2362903 Escherichia coli CFT073 1037789 NP_754411.1 CDS c2524 NC_004431.1 2362931 2363716 D Residues 37 to 261 of 261 are 91.18 pct identical to residues 1 to 227 of 227 from GenPept.129 : >dbj|BAB36222.1| (AP002559) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 2362931..2363716 Escherichia coli CFT073 1037791 NP_754412.1 CDS c2525 NC_004431.1 2363732 2364142 D Residues 1 to 135 of 136 are 95.55 pct identical to residues 1 to 135 of 136 from GenPept.129 : >dbj|BAB36223.1| (AP002559) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 2363732..2364142 Escherichia coli CFT073 1037792 NP_754413.1 CDS c2526 NC_004431.1 2364363 2365184 D Escherichia coli K-12 ortholog: b0252; Escherichia coli O157:H7 ortholog: z1655; hypothetical protein 2364363..2365184 Escherichia coli CFT073 1037793 NP_754414.1 CDS c2527 NC_004431.1 2365275 2365760 D Escherichia coli K-12 ortholog: b0248; Escherichia coli O157:H7 ortholog: z1656; hypothetical protein 2365275..2365760 Escherichia coli CFT073 1037794 NP_754415.1 CDS c2528 NC_004431.1 2365329 2365868 R Residues 1 to 174 of 179 are 87.93 pct identical to residues 125 to 298 of 319 from GenPept.129 : >gb|AAL67347.1|AF447814_15 (AF447814) unknown [Escherichia coli]; hypothetical protein complement(2365329..2365868) Escherichia coli CFT073 1037795 NP_754416.1 CDS c2529 NC_004431.1 2365806 2366252 D Escherichia coli K-12 ortholog: b2002; Escherichia coli O157:H7 ortholog: z1217; radC-like protein yeeS 2365806..2366252 Escherichia coli CFT073 1037797 NP_754417.1 CDS c2530 NC_004431.1 2366321 2366542 D Escherichia coli K-12 ortholog: b2003; Escherichia coli O157:H7 ortholog: z3163; hypothetical protein 2366321..2366542 Escherichia coli CFT073 1037801 NP_754418.1 CDS c2531 NC_004431.1 2366616 2366984 D Escherichia coli K-12 ortholog: b2004; Escherichia coli O157:H7 ortholog: z3164; hypothetical protein 2366616..2366984 Escherichia coli CFT073 1037802 NP_754419.1 CDS c2532 NC_004431.1 2367073 2367447 D Escherichia coli K-12 ortholog: b2005; Escherichia coli O157:H7 ortholog: z5091; hypothetical protein 2367073..2367447 Escherichia coli CFT073 1037803 NP_754420.1 CDS yeeW NC_004431.1 2367444 2367638 D Escherichia coli K-12 ortholog: b2006; Escherichia coli O157:H7 ortholog: z3166; hypothetical protein 2367444..2367638 Escherichia coli CFT073 1037804 NP_754421.1 CDS yeeX NC_004431.1 2368536 2368931 R Escherichia coli K-12 ortholog: b2007; Escherichia coli O157:H7 ortholog: z3168; hypothetical protein complement(2368536..2368931) Escherichia coli CFT073 1037806 NP_754422.1 CDS c2535 NC_004431.1 2368950 2369072 D hypothetical protein 2368950..2369072 Escherichia coli CFT073 1037807 NP_754423.1 CDS yeeA NC_004431.1 2369037 2370095 R Escherichia coli K-12 ortholog: b2008; Escherichia coli O157:H7 ortholog: z3169; hypothetical protein complement(2369037..2370095) Escherichia coli CFT073 1037809 NP_754424.1 CDS sbmC NC_004431.1 2370293 2370766 R SbmC protein; Escherichia coli K-12 ortholog: b2009; Escherichia coli O157:H7 ortholog: z3170; DNA gyrase inhibitor complement(2370293..2370766) Escherichia coli CFT073 1037810 NP_754425.1 CDS dacD NC_004431.1 2370885 2372057 R removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase complement(2370885..2372057) Escherichia coli CFT073 1037811 NP_754426.2 CDS sbcB NC_004431.1 2372260 2373687 D Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 2372260..2373687 Escherichia coli CFT073 1037812 NP_754427.1 CDS yeeF NC_004431.1 2373761 2375125 R Escherichia coli K-12 ortholog: b2014; Escherichia coli O157:H7 ortholog: z3176; transport protein YeeF complement(2373761..2375125) Escherichia coli CFT073 1037813 NP_754428.1 CDS c2541 NC_004431.1 2375301 2375438 R hypothetical protein complement(2375301..2375438) Escherichia coli CFT073 1037814 NP_754429.1 CDS yeeY NC_004431.1 2375386 2376336 R Escherichia coli K-12 ortholog: b2015; Escherichia coli O157:H7 ortholog: z3177; transcriptional regulator YeeY complement(2375386..2376336) Escherichia coli CFT073 1037816 NP_754430.1 CDS c2543 NC_004431.1 2376361 2377185 R Escherichia coli K-12 ortholog: b2016; Escherichia coli O157:H7 ortholog: z3178; hypothetical protein complement(2376361..2377185) Escherichia coli CFT073 1037817 NP_754431.1 CDS c2544 NC_004431.1 2377268 2377522 R Residues 1 to 84 of 84 are 98.80 pct identical to residues 1 to 84 of 84 from SwissProt.40 : >sp|P56605|YOEB_ECOLI Hypothetical protein yoeB; hypothetical protein complement(2377268..2377522) Escherichia coli CFT073 1037818 NP_754432.2 CDS yefM NC_004431.1 2377519 2377770 R Antitoxin that counteracts the effect of the YoeB toxin; antitoxin YefM complement(2377519..2377770) Escherichia coli CFT073 1037819 NP_754434.1 CDS hisG NC_004431.1 2378249 2379148 D long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2378249..2379148 Escherichia coli CFT073 1037821 NP_754435.1 CDS hisD NC_004431.1 2379145 2380458 D catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2379145..2380458 Escherichia coli CFT073 1037822 NP_754436.1 CDS hisC NC_004431.1 2380455 2381525 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2380455..2381525 Escherichia coli CFT073 1037823 NP_754437.2 CDS hisB NC_004431.1 2381525 2382592 D catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2381525..2382592 Escherichia coli CFT073 1037824 NP_754438.1 CDS hisH NC_004431.1 2382592 2383182 D with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2382592..2383182 Escherichia coli CFT073 1037825 NP_754439.2 CDS hisA NC_004431.1 2383182 2383919 D catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2383182..2383919 Escherichia coli CFT073 1037827 NP_754440.1 CDS hisF NC_004431.1 2383901 2384677 D catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2383901..2384677 Escherichia coli CFT073 1037828 NP_754441.1 CDS hisI NC_004431.1 2384671 2385282 D catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein 2384671..2385282 Escherichia coli CFT073 1037829 NP_754442.1 CDS wzzB NC_004431.1 2385469 2386482 R Polysaccharide antigen chain regulator; Escherichia coli K-12 ortholog: b2027; Escherichia coli O157:H7 ortholog: z3189; chain length determinant protein complement(2385469..2386482) Escherichia coli CFT073 1037830 NP_754443.1 CDS ugd NC_004431.1 2386589 2387755 R Escherichia coli K-12 ortholog: b2028; Escherichia coli O157:H7 ortholog: z3190; UDP-glucose 6-dehydrogenase complement(2386589..2387755) Escherichia coli CFT073 1037832 NP_754444.1 CDS gnd NC_004431.1 2388005 2389411 R catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase complement(2388005..2389411) Escherichia coli CFT073 1037833 NP_754445.1 CDS manB NC_004431.1 2389574 2390944 R Escherichia coli K-12 ortholog: b2048; Escherichia coli O157:H7 ortholog: z3194; phosphomannomutase complement(2389574..2390944) Escherichia coli CFT073 1037835 NP_754446.1 CDS c2558 NC_004431.1 2391027 2392478 R GDP; Escherichia coli K-12 ortholog: b2049; Escherichia coli O157:H7 ortholog: z3213; mannose-1-phosphate guanylyltransferase complement(2391027..2392478) Escherichia coli CFT073 1037836 NP_754447.1 CDS c2559 NC_004431.1 2392456 2393571 R Residues 2 to 365 of 371 are 50.00 pct identical to residues 28 to 394 of 399 from GenPept.129 : >gb|AAB49389.1| (M84642) orf7.17; function unknown [Salmonella enterica]; hypothetical protein complement(2392456..2393571) Escherichia coli CFT073 1037838 NP_754448.1 CDS c2560 NC_004431.1 2393682 2394689 R Escherichia coli K-12 ortholog: b0759; Escherichia coli O157:H7 ortholog: z0929; UDP-glucose 4-epimerase complement(2393682..2394689) Escherichia coli CFT073 1037839 NP_754449.1 CDS c2561 NC_004431.1 2394706 2395851 R Residues 83 to 355 of 381 are 22.83 pct identical to residues 512 to 777 of 812 from GenPept.129 : >gb|AAM04600.1| (AE010785) glycosyltransferase [Methanosarcina acetivorans str. C2A]; hypothetical protein complement(2394706..2395851) Escherichia coli CFT073 1037842 NP_754450.1 CDS c2562 NC_004431.1 2395838 2396920 R Residues 169 to 353 of 360 are 27.89 pct identical to residues 153 to 336 of 336 from GenPept.129 : >gb|AAL80431.1| (AE010155) glycosyltransferase [Pyrococcus furiosus DSM 3638]; glycosyl transferase complement(2395838..2396920) Escherichia coli CFT073 1037843 NP_754451.1 CDS c2563 NC_004431.1 2396866 2397735 R Residues 9 to 179 of 289 are 31.21 pct identical to residues 8 to 173 of 327 from GenPept.129 : >gb|AAC69672.1| (AF019746) beta1,3-glucosyltransferase WaaV [Escherichia coli]; glycosyl transferase complement(2396866..2397735) Escherichia coli CFT073 1037844 NP_754452.1 CDS c2564 NC_004431.1 2397732 2399093 R Residues 338 to 445 of 453 are 28.81 pct identical to residues 357 to 474 of 477 from GenPept.129 : >gb|AAL00026.1| (AE008494) Hypothetical protein [Streptococcus pneumoniae R6]; hypothetical protein complement(2397732..2399093) Escherichia coli CFT073 1037846 YP_004853815.1 CDS c2565 NC_004431.1 2398412 2398534 R hypothetical protein complement(2398412..2398534) Escherichia coli CFT073 1037848 NP_754454.1 CDS c2566 NC_004431.1 2399075 2400331 R Residues 11 to 409 of 418 are 24.94 pct identical to residues 7 to 412 of 431 from GenPept.129 : >gb|AAK81005.1|AE007803_8 (AE007803) Possible O-antigen/teichoic acid transporter [Clostridium acetobutylicum]; hypothetical protein complement(2399075..2400331) Escherichia coli CFT073 1037850 NP_754455.1 CDS galF NC_004431.1 2400688 2401593 R together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP-glucose-1-phosphate uridylyltransferase complement(2400688..2401593) Escherichia coli CFT073 1037852 NP_754456.1 CDS wcaM NC_004431.1 2401756 2403150 R WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; colanic acid biosynthesis protein complement(2401756..2403150) Escherichia coli CFT073 1037853 NP_754457.1 CDS wcaL NC_004431.1 2403161 2404381 R Escherichia coli K-12 ortholog: b2044; Escherichia coli O157:H7 ortholog: z3208; colanic acid biosynthesis glycosyl transferase wcaL complement(2403161..2404381) Escherichia coli CFT073 1037854 NP_754458.1 CDS wcaK NC_004431.1 2404378 2405658 R Escherichia coli K-12 ortholog: b2045; Escherichia coli O157:H7 ortholog: z3209; pyruvyl transferase complement(2404378..2405658) Escherichia coli CFT073 1037855 NP_754459.1 CDS wzxC NC_004431.1 2406127 2407605 R Escherichia coli K-12 ortholog: b2046; Escherichia coli O157:H7 ortholog: z3210; colanic acid exporter complement(2406127..2407605) Escherichia coli CFT073 1037856 NP_754460.1 CDS wcaJ NC_004431.1 2407607 2409001 R WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; UDP-glucose lipid carrier transferase complement(2407607..2409001) Escherichia coli CFT073 1037858 NP_754461.1 CDS cpsG NC_004431.1 2409057 2410475 R Escherichia coli K-12 ortholog: b2048; Escherichia coli O157:H7 ortholog: z3212; phosphomannomutase complement(2409057..2410475) Escherichia coli CFT073 1037861 NP_754462.1 CDS c2574 NC_004431.1 2410453 2410611 D hypothetical protein 2410453..2410611 Escherichia coli CFT073 1037864 NP_754463.1 CDS cpsB NC_004431.1 2410620 2412056 R GDP; Escherichia coli K-12 ortholog: b2049; Escherichia coli O157:H7 ortholog: z3213; mannose-1-phosphate guanylyltransferase complement(2410620..2412056) Escherichia coli CFT073 1037865 NP_754464.1 CDS wcaI NC_004431.1 2412059 2413282 R Escherichia coli K-12 ortholog: b2050; Escherichia coli O157:H7 ortholog: z3214; glycosyl transferase complement(2412059..2413282) Escherichia coli CFT073 1037867 NP_754465.1 CDS wcaH NC_004431.1 2413279 2413761 R Escherichia coli K-12 ortholog: b2051; Escherichia coli O157:H7 ortholog: z3215; GDP-mannose mannosyl hydrolase complement(2413279..2413761) Escherichia coli CFT073 1037868 NP_754466.1 CDS wcaG NC_004431.1 2413761 2414726 R Escherichia coli K-12 ortholog: b2052; Escherichia coli O157:H7 ortholog: z3216; bifunctional; GDP-fucose synthetase; GDP-mannose-4-keto-6-D epimerase; GDP-4-keto-6-L-galactose reductase complement(2413761..2414726) Escherichia coli CFT073 1037870 NP_754467.1 CDS gmd NC_004431.1 2414729 2415850 R Escherichia coli K-12 ortholog: b2053; Escherichia coli O157:H7 ortholog: z3217; GDP-mannose 4,6-dehydratase complement(2414729..2415850) Escherichia coli CFT073 1037872 NP_754468.1 CDS wcaF NC_004431.1 2415877 2416425 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); colanic acid biosynthesis acetyltransferase WcaF complement(2415877..2416425) Escherichia coli CFT073 1037873 NP_754469.1 CDS wcaE NC_004431.1 2416441 2417187 R Escherichia coli K-12 ortholog: b2055; Escherichia coli O157:H7 ortholog: z3219; glycosyl transferase complement(2416441..2417187) Escherichia coli CFT073 1037874 NP_754470.2 CDS wcaD NC_004431.1 2417198 2418415 R essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; colanic acid biosynthesis protein complement(2417198..2418415) Escherichia coli CFT073 1037877 NP_754471.1 CDS wcaC NC_004431.1 2418390 2419607 R Escherichia coli K-12 ortholog: b2057; Escherichia coli O157:H7 ortholog: z3221; glycosyl transferase complement(2418390..2419607) Escherichia coli CFT073 1037879 NP_754472.1 CDS wcaB NC_004431.1 2419604 2420092 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; colanic acid biosynthesis acetyltransferase WcaB complement(2419604..2420092) Escherichia coli CFT073 1037882 NP_754473.1 CDS wcaA NC_004431.1 2420095 2420934 R Escherichia coli K-12 ortholog: b2059; Escherichia coli O157:H7 ortholog: z3223; glycosyl transferase complement(2420095..2420934) Escherichia coli CFT073 1037883 NP_754474.2 CDS c2586 NC_004431.1 2421027 2423189 R Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase complement(2421027..2423189) Escherichia coli CFT073 1037884 NP_754475.1 CDS c2587 NC_004431.1 2423192 2423422 R Residues 1 to 76 of 76 are 98.68 pct identical to residues 72 to 147 of 147 from GenPept.129 : >gb|AAC77834.1| (U38473) acid phosphatase [Escherichia coli]; hypothetical protein complement(2423192..2423422) Escherichia coli CFT073 1037885 NP_754476.1 CDS c2588 NC_004431.1 2423638 2424141 R Residues 1 to 167 of 167 are 98.80 pct identical to residues 213 to 379 of 379 from GenPept.129 : >gb|AAG57122.1|AE005432_3 (AE005432) polysaccharide export protein [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(2423638..2424141) Escherichia coli CFT073 1037888 NP_754477.1 CDS c2589 NC_004431.1 2424132 2424776 R Residues 1 to 211 of 214 are 99.52 pct identical to residues 1 to 211 of 379 from MG1655 : b2062; hypothetical protein complement(2424132..2424776) Escherichia coli CFT073 1037890 NP_754478.1 CDS yegH NC_004431.1 2425369 2427018 D Escherichia coli K-12 ortholog: b2063; Escherichia coli O157:H7 ortholog: z3229; hypothetical protein 2425369..2427018 Escherichia coli CFT073 1037892 NP_754479.1 CDS asmA NC_004431.1 2427086 2428939 R YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; assembly protein complement(2427086..2428939) Escherichia coli CFT073 1037893 NP_754480.1 CDS dcd NC_004431.1 2428961 2429542 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(2428961..2429542) Escherichia coli CFT073 1037894 NP_754481.2 CDS udk NC_004431.1 2429634 2430275 R functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase complement(2429634..2430275) Escherichia coli CFT073 1037895 NP_754482.1 CDS yegE NC_004431.1 2430593 2433910 D contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction; sensor protein 2430593..2433910 Escherichia coli CFT073 1037897 NP_754483.1 CDS alkA NC_004431.1 2434020 2434868 R inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyl-adenine DNA glycosylase complement(2434020..2434868) Escherichia coli CFT073 1037898 NP_754484.2 CDS yegD NC_004431.1 2435002 2436354 D Escherichia coli K-12 ortholog: b2069; Escherichia coli O157:H7 ortholog: z3238; chaperone 2435002..2436354 Escherichia coli CFT073 1037901 NP_754485.1 CDS yegI NC_004431.1 2436367 2438316 R Escherichia coli K-12 ortholog: b2070; Escherichia coli O157:H7 ortholog: z3239; hypothetical protein complement(2436367..2438316) Escherichia coli CFT073 1037904 NP_754486.1 CDS yegK NC_004431.1 2438304 2439065 R Escherichia coli K-12 ortholog: b2072; Escherichia coli O157:H7 ortholog: z3240; hypothetical protein complement(2438304..2439065) Escherichia coli CFT073 1037905 NP_754487.1 CDS yegL NC_004431.1 2439062 2439721 R Escherichia coli K-12 ortholog: b2073; Escherichia coli O157:H7 ortholog: z3241; hypothetical protein complement(2439062..2439721) Escherichia coli CFT073 1037906 NP_754488.2 CDS yegM NC_004431.1 2440602 2441849 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2440602..2441849 Escherichia coli CFT073 1037908 NP_754489.1 CDS yegN NC_004431.1 2441849 2444971 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2441849..2444971 Escherichia coli CFT073 1037909 NP_754490.1 CDS yegO NC_004431.1 2444972 2448049 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2444972..2448049 Escherichia coli CFT073 1037912 NP_754491.1 CDS yegB NC_004431.1 2448050 2449465 D Escherichia coli K-12 ortholog: b2077; Escherichia coli O157:H7 ortholog: z3246; multidrug efflux system protein MdtE 2448050..2449465 Escherichia coli CFT073 1037913 NP_754492.1 CDS baeS NC_004431.1 2449462 2450865 D Escherichia coli K-12 ortholog: b2078; Escherichia coli O157:H7 ortholog: z3247; signal transduction histidine-protein kinase BaeS 2449462..2450865 Escherichia coli CFT073 1037914 NP_754493.1 CDS baeR NC_004431.1 2450862 2451584 D response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2450862..2451584 Escherichia coli CFT073 1037915 NP_754494.1 CDS yegP NC_004431.1 2451725 2452096 D Escherichia coli K-12 ortholog: b2080; Escherichia coli O157:H7 ortholog: z3249; hypothetical protein 2451725..2452096 Escherichia coli CFT073 1037916 NP_754495.1 CDS c2607 NC_004431.1 2452221 2452835 R Residues 6 to 204 of 204 are 37.61 pct identical to residues 1 to 205 of 205 from GenPept.129 : >emb|CAD02514.1| (AL627273) exported protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein complement(2452221..2452835) Escherichia coli CFT073 1037918 NP_754496.1 CDS c2608 NC_004431.1 2452887 2455034 R Residues 14 to 715 of 715 are 65.00 pct identical to residues 1 to 703 of 703 from GenPept.129 : >gb|AAL21038.1| (AE008795) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein complement(2452887..2455034) Escherichia coli CFT073 1037920 NP_754497.1 CDS c2609 NC_004431.1 2455006 2455722 R Residues 5 to 237 of 238 are 65.38 pct identical to residues 4 to 237 of 238 from GenPept.129 : >gb|AAL21037.1| (AE008795) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein complement(2455006..2455722) Escherichia coli CFT073 1037921 NP_754498.1 CDS c2610 NC_004431.1 2455722 2456936 R Residues 111 to 399 of 404 are 65.39 pct identical to residues 1 to 289 of 294 from GenPept.129 : >emb|CAD02496.1| (AL627273) hypothetical protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein complement(2455722..2456936) Escherichia coli CFT073 1037925 NP_754499.1 CDS yegQ NC_004431.1 2457424 2458785 D Escherichia coli K-12 ortholog: b2081; Escherichia coli O157:H7 ortholog: z3250; protease yegQ 2457424..2458785 Escherichia coli CFT073 1037927 NP_754500.1 CDS c2612 NC_004431.1 2458725 2458862 R hypothetical protein complement(2458725..2458862) Escherichia coli CFT073 1037928 NP_754501.1 CDS yegR NC_004431.1 2459285 2459617 R Escherichia coli K-12 ortholog: b2085; Escherichia coli O157:H7 ortholog: z3251; hypothetical protein complement(2459285..2459617) Escherichia coli CFT073 1037929 NP_754502.1 CDS yegS NC_004431.1 2460017 2460916 D cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2460017..2460916 Escherichia coli CFT073 1037932 NP_754503.1 CDS c2615 NC_004431.1 2460998 2461777 R Possible Fusion of Escherichia coli K-12 B2087 and B2091; Residues 1 to 259 of 259 are 99.61 pct identical to residues 1 to 259 of 259 from SwissProt.40 : >sp|P36930|GATR_ECOLI GALACTITOL UTILIZATION OPERON REPRESSOR; hypothetical protein complement(2460998..2461777) Escherichia coli CFT073 1037933 NP_754504.1 CDS gatD NC_004431.1 2461877 2462917 R Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase complement(2461877..2462917) Escherichia coli CFT073 1037934 NP_754505.1 CDS gatC NC_004431.1 2462965 2464320 R EIIC-GAT; Escherichia coli K-12 ortholog: b2092; Escherichia coli O157:H7 ortholog: z3255; PTS system, galactitol-specific IIC component complement(2462965..2464320) Escherichia coli CFT073 1037935 NP_754506.1 CDS gatB NC_004431.1 2464324 2464608 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB complement(2464324..2464608) Escherichia coli CFT073 1037936 NP_754507.1 CDS gatA NC_004431.1 2464639 2465091 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA complement(2464639..2465091) Escherichia coli CFT073 1037937 NP_754508.1 CDS gatZ NC_004431.1 2465101 2466363 R Escherichia coli K-12 ortholog: b2095; Escherichia coli O157:H7 ortholog: z3258; tagatose 6-phosphate kinase gatZ complement(2465101..2466363) Escherichia coli CFT073 1037939 NP_754509.2 CDS gatY NC_004431.1 2466392 2467246 R catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase complement(2466392..2467246) Escherichia coli CFT073 1037940 NP_754510.1 CDS c2622 NC_004431.1 2467471 2467980 R Residues 18 to 169 of 169 are 95.39 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; transposase complement(2467471..2467980) Escherichia coli CFT073 1037943 NP_754511.2 CDS c2623 NC_004431.1 2468184 2469236 R catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase complement(2468184..2469236) Escherichia coli CFT073 1037944 NP_754512.1 CDS c2624 NC_004431.1 2469295 2469441 D hypothetical protein 2469295..2469441 Escherichia coli CFT073 1037946 NP_754513.1 CDS yegT NC_004431.1 2469493 2470770 D Escherichia coli K-12 ortholog: b2098; Escherichia coli O157:H7 ortholog: z3261; nucleoside transporter yegT 2469493..2470770 Escherichia coli CFT073 1037948 NP_754514.1 CDS yegU NC_004431.1 2470767 2471771 D Escherichia coli K-12 ortholog: b2099; Escherichia coli O157:H7 ortholog: z3262; hypothetical protein 2470767..2471771 Escherichia coli CFT073 1037949 NP_754515.1 CDS yegV NC_004431.1 2471768 2472733 D Escherichia coli K-12 ortholog: b2100; Escherichia coli O157:H7 ortholog: z3263; sugar kinase yegV 2471768..2472733 Escherichia coli CFT073 1037950 NP_754516.1 CDS yegW NC_004431.1 2472707 2473453 R Escherichia coli K-12 ortholog: b2101; Escherichia coli O157:H7 ortholog: z3264; transcriptional regulator YegW complement(2472707..2473453) Escherichia coli CFT073 1037951 NP_754517.1 CDS yegX NC_004431.1 2473505 2474332 R Escherichia coli K-12 ortholog: b2102; Escherichia coli O157:H7 ortholog: z3266; hypothetical protein complement(2473505..2474332) Escherichia coli CFT073 1037952 NP_754518.1 CDS thiD NC_004431.1 2474388 2475188 R catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase complement(2474388..2475188) Escherichia coli CFT073 1037953 NP_754519.1 CDS thiM NC_004431.1 2475185 2475973 R catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase complement(2475185..2475973) Escherichia coli CFT073 1037956 NP_754520.1 CDS yohL NC_004431.1 2476196 2476468 R Escherichia coli K-12 ortholog: b2105; Escherichia coli O157:H7 ortholog: z3273; hypothetical protein complement(2476196..2476468) Escherichia coli CFT073 1037957 NP_754521.1 CDS yohM NC_004431.1 2476589 2477413 D membrane protein conferring nickel and cobalt resistance; nickel/cobalt efflux protein RcnA 2476589..2477413 Escherichia coli CFT073 1037958 NP_754522.1 CDS yohN NC_004431.1 2477452 2477970 D Escherichia coli K-12 ortholog: b2107; Escherichia coli O157:H7 ortholog: z3275; hypothetical protein 2477452..2477970 Escherichia coli CFT073 1037960 NP_754523.1 CDS yehA NC_004431.1 2478052 2479086 R Escherichia coli K-12 ortholog: b2108; hypothetical protein complement(2478052..2479086) Escherichia coli CFT073 1037961 NP_754524.1 CDS yehB NC_004431.1 2479102 2481597 R Escherichia coli K-12 ortholog: b2109; Escherichia coli O157:H7 ortholog: z3277; outer membrane usher protein yehB complement(2479102..2481597) Escherichia coli CFT073 1037962 NP_754525.1 CDS yehC NC_004431.1 2481598 2482272 R Escherichia coli K-12 ortholog: b2110; Escherichia coli O157:H7 ortholog: z3278; fimbrial chaperone yehC complement(2481598..2482272) Escherichia coli CFT073 1037963 NP_754526.1 CDS yehD NC_004431.1 2482353 2482895 R Escherichia coli K-12 ortholog: b2111; Escherichia coli O157:H7 ortholog: z3279; hypothetical protein complement(2482353..2482895) Escherichia coli CFT073 1037964 NP_754527.1 CDS c2639 NC_004431.1 2483231 2483740 R Residues 18 to 169 of 169 are 94.07 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; transposase complement(2483231..2483740) Escherichia coli CFT073 1037965 NP_754528.1 CDS yehE NC_004431.1 2483901 2484182 R Escherichia coli K-12 ortholog: b2112; Escherichia coli O157:H7 ortholog: z3280; hypothetical protein complement(2483901..2484182) Escherichia coli CFT073 1037966 NP_754529.2 CDS mrp NC_004431.1 2484445 2485554 R Escherichia coli K-12 ortholog: b2113; Escherichia coli O157:H7 ortholog: z3281; ATPase complement(2484445..2485554) Escherichia coli CFT073 1037967 NP_754530.1 CDS metG NC_004431.1 2485677 2487719 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2485677..2487719 Escherichia coli CFT073 1037968 NP_754531.1 CDS c2643 NC_004431.1 2487860 2491648 D Fusion of Escherichia coli K-12 B2115 and B2116; Residues 313 to 949 of 1262 are 81.12 pct identical to residues 1 to 639 of 645 from MG1655 : b2116; hypothetical protein 2487860..2491648 Escherichia coli CFT073 1037969 NP_754532.1 CDS yehI NC_004431.1 2491658 2495290 D Escherichia coli K-12 ortholog: b2118; Escherichia coli O157:H7 ortholog: z3287; hypothetical protein 2491658..2495290 Escherichia coli CFT073 1037971 NP_754535.1 CDS c2647 NC_004431.1 2495351 2495536 D Residues 1 to 60 of 61 are 94.99 pct identical to residues 1 to 60 of 105 from GenPept.129 : >gb|AAA60479.1| (U00007) yehK [Escherichia coli]; hypothetical protein 2495351..2495536 Escherichia coli CFT073 1037975 NP_754536.1 CDS c2648 NC_004431.1 2495373 2495543 D hypothetical protein 2495373..2495543 Escherichia coli CFT073 1037978 NP_754537.1 CDS yehL NC_004431.1 2496233 2497387 D Escherichia coli K-12 ortholog: b2119; Escherichia coli O157:H7 ortholog: z3291; hypothetical protein 2496233..2497387 Escherichia coli CFT073 1037981 NP_754538.1 CDS yehM NC_004431.1 2497323 2499677 D Escherichia coli K-12 ortholog: b2120; Escherichia coli O157:H7 ortholog: z3292; hypothetical protein 2497323..2499677 Escherichia coli CFT073 1037982 NP_754539.1 CDS yehP NC_004431.1 2499607 2500806 D Escherichia coli K-12 ortholog: b2121; Escherichia coli O157:H7 ortholog: z3294; hypothetical protein 2499607..2500806 Escherichia coli CFT073 1037983 NP_754540.1 CDS yehQ NC_004431.1 2500803 2502806 D Escherichia coli K-12 ortholog: b2122; Escherichia coli O157:H7 ortholog: z3295; hypothetical protein 2500803..2502806 Escherichia coli CFT073 1037985 NP_754541.1 CDS yehR NC_004431.1 2502919 2503392 D Escherichia coli K-12 ortholog: b2123; Escherichia coli O157:H7 ortholog: z3300; lipoprotein yehR 2502919..2503392 Escherichia coli CFT073 1037987 NP_754542.1 CDS yehS NC_004431.1 2503433 2503960 R Escherichia coli K-12 ortholog: b2124; Escherichia coli O157:H7 ortholog: z3301; hypothetical protein complement(2503433..2503960) Escherichia coli CFT073 1037988 NP_754543.1 CDS yehT NC_004431.1 2503950 2504684 R unknown function; when overproduced it confers drug-resistance; two-component response-regulatory protein YehT complement(2503950..2504684) Escherichia coli CFT073 1037989 NP_754544.1 CDS yehU NC_004431.1 2504666 2506366 R Escherichia coli K-12 ortholog: b2126; Escherichia coli O157:H7 ortholog: z3303; hypothetical protein complement(2504666..2506366) Escherichia coli CFT073 1037992 NP_754545.1 CDS yehV NC_004431.1 2506573 2507304 D Escherichia coli K-12 ortholog: b2127; Escherichia coli O157:H7 ortholog: z3376; MerR-like regulator A 2506573..2507304 Escherichia coli CFT073 1037994 NP_754546.1 CDS yehW NC_004431.1 2507452 2508183 R Escherichia coli K-12 ortholog: b2128; Escherichia coli O157:H7 ortholog: z3377; ABC transporter permease complement(2507452..2508183) Escherichia coli CFT073 1037996 NP_754547.1 CDS yehX NC_004431.1 2508188 2509114 R Escherichia coli K-12 ortholog: b2129; Escherichia coli O157:H7 ortholog: z3378; ABC transporter ATP-binding protein complement(2508188..2509114) Escherichia coli CFT073 1037997 NP_754548.1 CDS yehY NC_004431.1 2509107 2510264 R Escherichia coli K-12 ortholog: b2130; Escherichia coli O157:H7 ortholog: z3379; ABC transporter permease complement(2509107..2510264) Escherichia coli CFT073 1037998 NP_754549.1 CDS yehZ NC_004431.1 2510271 2511188 R Escherichia coli K-12 ortholog: b2131; Escherichia coli O157:H7 ortholog: z3380; hypothetical protein complement(2510271..2511188) Escherichia coli CFT073 1038000 NP_754550.1 CDS c2662 NC_004431.1 2511219 2511371 R hypothetical protein complement(2511219..2511371) Escherichia coli CFT073 1038002 NP_754551.1 CDS bglX NC_004431.1 2511378 2513675 R Escherichia coli K-12 ortholog: b2132; Escherichia coli O157:H7 ortholog: z3381; periplasmic beta-glucosidase complement(2511378..2513675) Escherichia coli CFT073 1038003 NP_754552.2 CDS dld NC_004431.1 2513871 2515586 D component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2513871..2515586 Escherichia coli CFT073 1038004 NP_754553.1 CDS pbpG NC_004431.1 2515625 2516566 R specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase complement(2515625..2516566) Escherichia coli CFT073 1038005 NP_754554.1 CDS c2666 NC_004431.1 2516636 2516758 R hypothetical protein complement(2516636..2516758) Escherichia coli CFT073 1038006 NP_754555.1 CDS yohC NC_004431.1 2516731 2517342 R Escherichia coli K-12 ortholog: b2135; Escherichia coli O157:H7 ortholog: z3384; hypothetical protein complement(2516731..2517342) Escherichia coli CFT073 1038007 NP_754556.1 CDS yohD NC_004431.1 2517452 2518066 D Escherichia coli K-12 ortholog: b2136; Escherichia coli O157:H7 ortholog: z3385; hypothetical protein 2517452..2518066 Escherichia coli CFT073 1038008 NP_754557.1 CDS c2669 NC_004431.1 2518186 2518572 R Residues 1 to 128 of 128 are 97.65 pct identical to residues 126 to 253 of 253 from GenPept.129 : >gb|AAC75198.1| (AE000303) oxidoreductase [Escherichia coli K12]; hypothetical protein complement(2518186..2518572) Escherichia coli CFT073 1038009 NP_754558.1 CDS c2670 NC_004431.1 2518639 2518947 R Residues 1 to 102 of 102 are 99.01 pct identical to residues 1 to 102 of 253 from MG1655 : b2137; hypothetical protein complement(2518639..2518947) Escherichia coli CFT073 1038010 NP_754559.2 CDS yohG NC_004431.1 2519000 2520436 R may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance outer membrane protein MdtQ complement(2519000..2520436) Escherichia coli CFT073 1038011 NP_754560.1 CDS yohI NC_004431.1 2521130 2522146 R Escherichia coli K-12 ortholog: b2140; Escherichia coli O157:H7 ortholog: z3389; tRNA-dihydrouridine synthase C complement(2521130..2522146) Escherichia coli CFT073 1038012 NP_754561.1 CDS yohJ NC_004431.1 2522283 2522717 D Escherichia coli K-12 ortholog: b2141; Escherichia coli O157:H7 ortholog: z3396; hypothetical protein 2522283..2522717 Escherichia coli CFT073 1038017 NP_754562.1 CDS yohK NC_004431.1 2522714 2523409 D Escherichia coli K-12 ortholog: b2142; Escherichia coli O157:H7 ortholog: z3397; hypothetical protein 2522714..2523409 Escherichia coli CFT073 1038018 NP_754563.1 CDS cdd NC_004431.1 2523539 2524423 D Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2523539..2524423 Escherichia coli CFT073 1038019 NP_754564.1 CDS c2676 NC_004431.1 2524268 2524396 R hypothetical protein complement(2524268..2524396) Escherichia coli CFT073 1038022 NP_754565.1 CDS sanA NC_004431.1 2524573 2525292 D Escherichia coli K-12 ortholog: b2144; Escherichia coli O157:H7 ortholog: z3399; hypothetical protein 2524573..2525292 Escherichia coli CFT073 1038023 NP_754566.1 CDS yeiS NC_004431.1 2525295 2525534 D Escherichia coli K-12 ortholog: b2145; Escherichia coli O157:H7 ortholog: z3400; hypothetical protein 2525295..2525534 Escherichia coli CFT073 1038024 NP_754567.1 CDS yeiT NC_004431.1 2525728 2526966 D function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; oxidoreductase 2525728..2526966 Escherichia coli CFT073 1038025 NP_754568.2 CDS yeiA NC_004431.1 2526960 2528195 D catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2526960..2528195 Escherichia coli CFT073 1038027 NP_754569.1 CDS c2681 NC_004431.1 2528217 2528360 D hypothetical protein 2528217..2528360 Escherichia coli CFT073 1038028 NP_754570.1 CDS mglC NC_004431.1 2528438 2529448 R ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane component complement(2528438..2529448) Escherichia coli CFT073 1038030 NP_754571.1 CDS mglA NC_004431.1 2529464 2530984 R with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein complement(2529464..2530984) Escherichia coli CFT073 1038032 NP_754572.1 CDS mglB NC_004431.1 2531045 2532043 R GBP; Escherichia coli K-12 ortholog: b2150; Escherichia coli O157:H7 ortholog: z3405; D-galactose-binding periplasmic protein complement(2531045..2532043) Escherichia coli CFT073 1038033 NP_754573.1 CDS galS NC_004431.1 2532323 2533369 R negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS complement(2532323..2533369) Escherichia coli CFT073 1038035 NP_754574.1 CDS c2686 NC_004431.1 2533353 2533556 D hypothetical protein 2533353..2533556 Escherichia coli CFT073 1038040 NP_754575.1 CDS yeiB NC_004431.1 2533505 2534662 R Escherichia coli K-12 ortholog: b2152; Escherichia coli O157:H7 ortholog: z3408; hypothetical protein complement(2533505..2534662) Escherichia coli CFT073 1038046 NP_754576.1 CDS folE NC_004431.1 2534679 2535347 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(2534679..2535347) Escherichia coli CFT073 1038047 NP_754577.1 CDS yeiG NC_004431.1 2535605 2536441 D Escherichia coli K-12 ortholog: b2154; Escherichia coli O157:H7 ortholog: z3410; hypothetical protein 2535605..2536441 Escherichia coli CFT073 1038049 NP_754578.2 CDS cirA NC_004431.1 2536473 2538464 R Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor complement(2536473..2538464) Escherichia coli CFT073 1038050 NP_754579.1 CDS lysP NC_004431.1 2538756 2540225 R Escherichia coli K-12 ortholog: b2156; Escherichia coli O157:H7 ortholog: z3413; lysine transporter complement(2538756..2540225) Escherichia coli CFT073 1038051 NP_754580.1 CDS yeiE NC_004431.1 2540430 2541311 R Escherichia coli K-12 ortholog: b2157; Escherichia coli O157:H7 ortholog: z3414; DNA-binding transcriptional regulator complement(2540430..2541311) Escherichia coli CFT073 1038054 NP_754581.1 CDS yeiH NC_004431.1 2541410 2542459 D Escherichia coli K-12 ortholog: b2158; Escherichia coli O157:H7 ortholog: z3415; hypothetical protein 2541410..2542459 Escherichia coli CFT073 1038057 NP_754582.1 CDS nfo NC_004431.1 2542533 2543390 D Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2542533..2543390 Escherichia coli CFT073 1038059 NP_754583.1 CDS yeiI NC_004431.1 2543394 2544482 D Escherichia coli K-12 ortholog: b2160; Escherichia coli O157:H7 ortholog: z3417; hypothetical protein 2543394..2544482 Escherichia coli CFT073 1038060 NP_754584.1 CDS rihB NC_004431.1 2544750 2545691 R Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 complement(2544750..2545691) Escherichia coli CFT073 1038061 NP_754585.1 CDS yeiL NC_004431.1 2545821 2546519 D activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 2545821..2546519 Escherichia coli CFT073 1038064 NP_754586.1 CDS yeiM NC_004431.1 2546586 2547836 R Escherichia coli K-12 ortholog: b2164; Escherichia coli O157:H7 ortholog: z3421; transport protein YeiM complement(2546586..2547836) Escherichia coli CFT073 1038065 NP_754587.1 CDS yeiC NC_004431.1 2548858 2549913 R Escherichia coli K-12 ortholog: b2166; Escherichia coli O157:H7 ortholog: z3423; hypothetical protein complement(2548858..2549913) Escherichia coli CFT073 1038072 NP_754588.1 CDS fruA NC_004431.1 2550255 2551946 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunits IIBC complement(2550255..2551946) Escherichia coli CFT073 1038073 NP_754589.1 CDS fruK NC_004431.1 2551963 2552901 R converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase complement(2551963..2552901) Escherichia coli CFT073 1038075 NP_754590.1 CDS fruB NC_004431.1 2552901 2554031 R phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein complement(2552901..2554031) Escherichia coli CFT073 1038076 NP_754591.1 CDS c2705 NC_004431.1 2554196 2554327 D hypothetical protein 2554196..2554327 Escherichia coli CFT073 1038077 NP_754592.1 CDS yeiO NC_004431.1 2554398 2555579 D Escherichia coli K-12 ortholog: b2170; Escherichia coli O157:H7 ortholog: z3428; sugar efflux transporter B 2554398..2555579 Escherichia coli CFT073 1038078 NP_754593.1 CDS c2707 NC_004431.1 2555576 2555764 R Residues 1 to 62 of 62 are 100.00 pct identical to residues 23 to 84 of 84 from SwissProt.40 : >sp|P58039|YEIW_ECOLI Hypothetical protein yeiW; hypothetical protein complement(2555576..2555764) Escherichia coli CFT073 1038079 NP_754594.2 CDS yeiP NC_004431.1 2555985 2556557 D Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 2555985..2556557 Escherichia coli CFT073 1038080 NP_754595.1 CDS yeiQ NC_004431.1 2556771 2558246 D Escherichia coli K-12 ortholog: b2172; Escherichia coli O157:H7 ortholog: z3431; oxidoreductase yeiQ 2556771..2558246 Escherichia coli CFT073 1038083 NP_754596.1 CDS yeiR NC_004431.1 2558364 2559350 D Escherichia coli K-12 ortholog: b2173; Escherichia coli O157:H7 ortholog: z3432; hypothetical protein 2558364..2559350 Escherichia coli CFT073 1038085 NP_754597.1 CDS yeiU NC_004431.1 2559353 2560102 D Escherichia coli K-12 ortholog: b2174; Escherichia coli O157:H7 ortholog: z3433; hypothetical protein 2559353..2560102 Escherichia coli CFT073 1038091 NP_754598.1 CDS spr NC_004431.1 2560514 2561080 D by similarity, Spr seems to have peptidase activity; involved in thermoresistance; outer membrane lipoprotein 2560514..2561080 Escherichia coli CFT073 1038092 NP_754599.1 CDS rtn NC_004431.1 2561261 2562817 D Escherichia coli K-12 ortholog: b2176; Escherichia coli O157:H7 ortholog: z3435; hypothetical protein 2561261..2562817 Escherichia coli CFT073 1038093 NP_754600.3 CDS yejA NC_004431.1 2562893 2564713 D Escherichia coli K-12 ortholog: b2177; Escherichia coli O157:H7 ortholog: z3436; hypothetical protein 2562893..2564713 Escherichia coli CFT073 1038094 NP_754601.1 CDS yejB NC_004431.1 2564714 2565808 D Escherichia coli K-12 ortholog: b2178; Escherichia coli O157:H7 ortholog: z3437; ABC transporter permease 2564714..2565808 Escherichia coli CFT073 1038098 NP_754602.1 CDS yejE NC_004431.1 2565808 2566833 D Escherichia coli K-12 ortholog: b2179; Escherichia coli O157:H7 ortholog: z3438; ABC transporter permease 2565808..2566833 Escherichia coli CFT073 1038107 NP_754603.1 CDS yejF NC_004431.1 2566835 2568424 D Escherichia coli K-12 ortholog: b2180; Escherichia coli O157:H7 ortholog: z3439; ABC transporter ATP-binding protein 2566835..2568424 Escherichia coli CFT073 1038108 NP_754604.1 CDS yejG NC_004431.1 2568428 2568772 R Escherichia coli K-12 ortholog: b2181; Escherichia coli O157:H7 ortholog: z3440; hypothetical protein complement(2568428..2568772) Escherichia coli CFT073 1038109 NP_754605.1 CDS bcr NC_004431.1 2569106 2570296 R Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system complement(2569106..2570296) Escherichia coli CFT073 1038111 NP_754606.3 CDS rsuA NC_004431.1 2570324 2571115 R catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A complement(2570324..2571115) Escherichia coli CFT073 1038113 NP_754607.1 CDS yejH NC_004431.1 2571169 2572929 D Escherichia coli K-12 ortholog: b2184; Escherichia coli O157:H7 ortholog: z3443; hypothetical protein 2571169..2572929 Escherichia coli CFT073 1038117 NP_754609.1 CDS c2723 NC_004431.1 2573039 2573470 R hypothetical protein complement(2573039..2573470) Escherichia coli CFT073 1038124 NP_754608.2 CDS rplY NC_004431.1 2573054 2573338 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 2573054..2573338 Escherichia coli CFT073 1038122 NP_754610.1 CDS yejK NC_004431.1 2573477 2574484 R Escherichia coli K-12 ortholog: b2186; Escherichia coli O157:H7 ortholog: z3445; nucleoid-associated protein NdpA complement(2573477..2574484) Escherichia coli CFT073 1038125 NP_754611.1 CDS yejL NC_004431.1 2574666 2574893 D Escherichia coli K-12 ortholog: b2187; Escherichia coli O157:H7 ortholog: z3446; hypothetical protein 2574666..2574893 Escherichia coli CFT073 1038128 NP_754612.1 CDS yejM NC_004431.1 2574913 2576673 D Escherichia coli K-12 ortholog: b2188; Escherichia coli O157:H7 ortholog: z3447; hypothetical protein 2574913..2576673 Escherichia coli CFT073 1038130 NP_754613.1 CDS c2727 NC_004431.1 2576926 2577081 R Residues 1 to 42 of 51 are 97.61 pct identical to residues 575 to 616 of 836 from GenPept.129 : >gb|AAG57327.1|AE005451_8 (AE005451) ATP-binding component of a transport system [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(2576926..2577081) Escherichia coli CFT073 1038135 NP_754614.1 CDS c2728 NC_004431.1 2577062 2577190 R Residues 3 to 35 of 42 are 100.00 pct identical to residues 536 to 568 of 836 from GenPept.129 : >gb|AAG57327.1|AE005451_8 (AE005451) ATP-binding component of a transport system [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(2577062..2577190) Escherichia coli CFT073 1038136 NP_754615.1 CDS c2729 NC_004431.1 2577163 2577552 R Residues 53 to 81 of 129 are 89.65 pct identical to residues 465 to 493 of 836 from GenPept.129 : >gb|AAG57327.1|AE005451_8 (AE005451) ATP-binding component of a transport system [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(2577163..2577552) Escherichia coli CFT073 1038137 NP_754616.1 CDS narP NC_004431.1 2578154 2578831 D nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 2578154..2578831 Escherichia coli CFT073 1038138 NP_754617.1 CDS ccmH NC_004431.1 2578866 2579918 R Escherichia coli K-12 ortholog: b2194; Escherichia coli O157:H7 ortholog: z3451; cytochrome c-type biogenesis protein ccmH complement(2578866..2579918) Escherichia coli CFT073 1038140 NP_754618.1 CDS dsbE NC_004431.1 2579915 2580472 R Cytochrome c biogenesis protein ccmG; Escherichia coli K-12 ortholog: b2195; Escherichia coli O157:H7 ortholog: z3452; Thiol:disulfide interchange protein dsbE complement(2579915..2580472) Escherichia coli CFT073 1038141 NP_754619.1 CDS ccmF NC_004431.1 2580469 2582412 R Escherichia coli K-12 ortholog: b2196; Escherichia coli O157:H7 ortholog: z3453; cytochrome c-type biogenesis protein ccmF complement(2580469..2582412) Escherichia coli CFT073 1038142 NP_754620.1 CDS ccmE NC_004431.1 2582409 2582888 R CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE complement(2582409..2582888) Escherichia coli CFT073 1038144 NP_754621.1 CDS ccmD NC_004431.1 2582885 2583094 R Cytochrome c-type biogenesis protein ccmD; Escherichia coli K-12 ortholog: b2198; Escherichia coli O157:H7 ortholog: z3455; Heme exporter protein D complement(2582885..2583094) Escherichia coli CFT073 1038146 NP_754622.1 CDS ccmC NC_004431.1 2583091 2583852 R Cytochrome c-type biogenesis protein ccmC; Escherichia coli K-12 ortholog: b2199; Escherichia coli O157:H7 ortholog: z3456; Heme exporter protein C complement(2583091..2583852) Escherichia coli CFT073 1038147 NP_754623.1 CDS ccmB NC_004431.1 2583870 2584532 R Cytochrome c-type biogenesis protein ccmB; Escherichia coli K-12 ortholog: b2200; Escherichia coli O157:H7 ortholog: z3457; Heme exporter protein B complement(2583870..2584532) Escherichia coli CFT073 1038148 NP_754624.1 CDS ccmA NC_004431.1 2584529 2585152 R ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA complement(2584529..2585152) Escherichia coli CFT073 1038149 NP_754625.1 CDS napC NC_004431.1 2585165 2585767 R with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC complement(2585165..2585767) Escherichia coli CFT073 1038151 NP_754626.1 CDS c2740 NC_004431.1 2585204 2585797 D hypothetical protein 2585204..2585797 Escherichia coli CFT073 1038152 NP_754627.2 CDS napB NC_004431.1 2585777 2586226 R small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit complement(2585777..2586226) Escherichia coli CFT073 1038153 NP_754628.1 CDS c2742 NC_004431.1 2585846 2586388 D hypothetical protein 2585846..2586388 Escherichia coli CFT073 1038157 NP_754629.1 CDS napH NC_004431.1 2586223 2587086 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component complement(2586223..2587086) Escherichia coli CFT073 1038161 NP_754630.1 CDS napG NC_004431.1 2587073 2587768 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component complement(2587073..2587768) Escherichia coli CFT073 1038162 NP_754631.1 CDS napA NC_004431.1 2587775 2590261 R periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit complement(2587775..2590261) Escherichia coli CFT073 1038163 NP_754632.1 CDS napD NC_004431.1 2590258 2590521 R Escherichia coli K-12 ortholog: b2207; Escherichia coli O157:H7 ortholog: z3464; assembly protein for periplasmic nitrate reductase complement(2590258..2590521) Escherichia coli CFT073 1038165 NP_754633.1 CDS napF NC_004431.1 2590511 2591005 R Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA.; ferredoxin-type protein complement(2590511..2591005) Escherichia coli CFT073 1038166 NP_754634.1 CDS c2748 NC_004431.1 2591105 2591278 D hypothetical protein 2591105..2591278 Escherichia coli CFT073 1038167 NP_754635.1 CDS c2749 NC_004431.1 2591198 2591326 R hypothetical protein complement(2591198..2591326) Escherichia coli CFT073 1038168 NP_754636.1 CDS eco NC_004431.1 2591392 2591901 D serine protease inhibitor, inhibits trypsin and other proteases; ecotin 2591392..2591901 Escherichia coli CFT073 1038169 NP_754637.1 CDS yojH NC_004431.1 2592051 2593697 R malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase complement(2592051..2593697) Escherichia coli CFT073 1038170 NP_754638.1 CDS yojI NC_004431.1 2593915 2595558 R efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane component/ATP-binding component complement(2593915..2595558) Escherichia coli CFT073 1038174 NP_754639.1 CDS alkB NC_004431.1 2595634 2596284 R Escherichia coli K-12 ortholog: b2212; Escherichia coli O157:H7 ortholog: z3470; alkylated DNA repair protein AlkB complement(2595634..2596284) Escherichia coli CFT073 1038177 NP_754640.1 CDS ada NC_004431.1 2596284 2597348 R Regulatory protein of adaptative response; Escherichia coli K-12 ortholog: b2213; Escherichia coli O157:H7 ortholog: z3471; bifunctional; ADA regulatory protein complement(2596284..2597348) Escherichia coli CFT073 1038183 NP_754641.1 CDS c2755 NC_004431.1 2597082 2597300 D Residues 8 to 56 of 72 are 77.55 pct identical to residues 1 to 49 of 117 from GenPept.129 : >dbj|BAB47178.1| (AB058960) inverted ada-Golga3 fusion protein [Mus musculus]; hypothetical protein 2597082..2597300 Escherichia coli CFT073 1038184 NP_754642.1 CDS yojL NC_004431.1 2597422 2598477 R catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE complement(2597422..2598477) Escherichia coli CFT073 1038186 NP_754643.1 CDS c2757 NC_004431.1 2598529 2599623 D Residues 20 to 72 of 364 are 60.37 pct identical to residues 16 to 68 of 69 from GenPept.129 : >gb|AAA32302.1| (J02580) ORF1 [Bacteriophage PA-2]; hypothetical protein 2598529..2599623 Escherichia coli CFT073 1038187 NP_754644.1 CDS ompC NC_004431.1 2598589 2599716 R allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C complement(2598589..2599716) Escherichia coli CFT073 1038188 NP_754645.1 CDS yojN NC_004431.1 2600455 2603127 D Escherichia coli K-12 ortholog: b2216; Escherichia coli O157:H7 ortholog: z3475; phosphotransfer intermediate protein in two-component regulatory system with RcsBC 2600455..2603127 Escherichia coli CFT073 1038191 NP_754646.1 CDS rcsB NC_004431.1 2603099 2603794 D two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 2603099..2603794 Escherichia coli CFT073 1038196 NP_754647.1 CDS rcsC NC_004431.1 2603880 2606729 R Escherichia coli K-12 ortholog: b2218; Escherichia coli O157:H7 ortholog: z3477; hybrid sensory kinase in two-component regulatory system with RcsB and YojN complement(2603880..2606729) Escherichia coli CFT073 1038197 NP_754648.1 CDS atoS NC_004431.1 2606884 2608722 D with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; sensory histidine kinase AtoS 2606884..2608722 Escherichia coli CFT073 1038209 NP_754649.1 CDS atoC NC_004431.1 2608719 2610104 D with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; acetoacetate metabolism regulatory protein AtoC 2608719..2610104 Escherichia coli CFT073 1038223 NP_754650.1 CDS atoD NC_004431.1 2610300 2610962 D Escherichia coli K-12 ortholog: b2221; acetyl-CoA:acetoacetyl-CoA transferase subunit alpha 2610300..2610962 Escherichia coli CFT073 1038225 NP_754651.1 CDS atoA NC_004431.1 2610962 2611612 D Escherichia coli K-12 ortholog: b2222; acetate CoA-transferase beta subunit 2610962..2611612 Escherichia coli CFT073 1038227 NP_754652.1 CDS atoE NC_004431.1 2611609 2612931 D Escherichia coli K-12 ortholog: b2223; Short-chain fatty acids transporter 2611609..2612931 Escherichia coli CFT073 1038247 NP_754653.1 CDS atoB NC_004431.1 2612962 2614146 D Escherichia coli K-12 ortholog: b2224; Escherichia coli O157:H7 ortholog: z4164; Acetyl-CoA acetyltransferase 2612962..2614146 Escherichia coli CFT073 1038272 NP_754654.1 CDS yfaP NC_004431.1 2614220 2614996 R Escherichia coli K-12 ortholog: b2225; Escherichia coli O157:H7 ortholog: z3478; hypothetical protein complement(2614220..2614996) Escherichia coli CFT073 1038273 NP_754655.1 CDS yfaQ NC_004431.1 2615001 2616650 R Escherichia coli K-12 ortholog: b2226; hypothetical protein complement(2615001..2616650) Escherichia coli CFT073 1038275 NP_754656.1 CDS c2770 NC_004431.1 2616651 2621180 R Escherichia coli K-12 ortholog: b2228; Escherichia coli O157:H7 ortholog: z3481; hypothetical protein complement(2616651..2621180) Escherichia coli CFT073 1038276 NP_754657.3 CDS yfaT NC_004431.1 2621189 2621839 R Escherichia coli K-12 ortholog: b2229; Escherichia coli O157:H7 ortholog: z3482; hypothetical protein complement(2621189..2621839) Escherichia coli CFT073 1038279 NP_754658.3 CDS yfaA NC_004431.1 2621809 2623545 R Escherichia coli K-12 ortholog: b2230; Escherichia coli O157:H7 ortholog: z3483; hypothetical protein complement(2621809..2623545) Escherichia coli CFT073 1038280 NP_754659.1 CDS gyrA NC_004431.1 2623646 2626273 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A complement(2623646..2626273) Escherichia coli CFT073 1038282 NP_754660.1 CDS ubiG NC_004431.1 2626420 2627142 D Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 2626420..2627142 Escherichia coli CFT073 1038283 NP_754661.1 CDS yfaL NC_004431.1 2627282 2631046 R Escherichia coli K-12 ortholog: b2233; Escherichia coli O157:H7 ortholog: z3487; adhesin complement(2627282..2631046) Escherichia coli CFT073 1038285 NP_754662.1 CDS nrdA NC_004431.1 2631722 2634007 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2631722..2634007 Escherichia coli CFT073 1038290 NP_754663.1 CDS nrdB NC_004431.1 2634197 2635327 D B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 2634197..2635327 Escherichia coli CFT073 1038291 NP_754664.1 CDS yfaE NC_004431.1 2635327 2635581 D plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 2635327..2635581 Escherichia coli CFT073 1038293 NP_754665.1 CDS inaA NC_004431.1 2635635 2636285 R Escherichia coli K-12 ortholog: b2237; Escherichia coli O157:H7 ortholog: z3493; hypothetical protein complement(2635635..2636285) Escherichia coli CFT073 1038295 NP_754666.1 CDS glpQ NC_004431.1 2636488 2637564 R hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase complement(2636488..2637564) Escherichia coli CFT073 1038296 NP_754667.1 CDS glpT NC_004431.1 2637569 2638927 R catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter complement(2637569..2638927) Escherichia coli CFT073 1038297 NP_754668.1 CDS glpA NC_004431.1 2639200 2640828 D anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 2639200..2640828 Escherichia coli CFT073 1038298 NP_754669.1 CDS glpB NC_004431.1 2640746 2642077 D sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 2640746..2642077 Escherichia coli CFT073 1038299 NP_754670.2 CDS glpC NC_004431.1 2642074 2643264 D anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 2642074..2643264 Escherichia coli CFT073 1038304 NP_754671.1 CDS c2785 NC_004431.1 2643289 2643414 D hypothetical protein 2643289..2643414 Escherichia coli CFT073 1038305 NP_754672.1 CDS yfaD NC_004431.1 2643457 2644383 D Escherichia coli K-12 ortholog: b2244; Escherichia coli O157:H7 ortholog: z3502; hypothetical protein 2643457..2644383 Escherichia coli CFT073 1038306 NP_754673.1 CDS yfaU NC_004431.1 2644424 2645227 R Escherichia coli K-12 ortholog: b2245; Escherichia coli O157:H7 ortholog: z3503; aldolase complement(2644424..2645227) Escherichia coli CFT073 1038307 NP_754674.1 CDS yfaV NC_004431.1 2645245 2646573 R Escherichia coli K-12 ortholog: b2246; Escherichia coli O157:H7 ortholog: z3504; transport protein YfaV complement(2645245..2646573) Escherichia coli CFT073 1038308 NP_754675.1 CDS yfaW NC_004431.1 2646591 2647808 R Escherichia coli K-12 ortholog: b2247; Escherichia coli O157:H7 ortholog: z3505; hypothetical protein complement(2646591..2647808) Escherichia coli CFT073 1038311 NP_754676.1 CDS yfaX NC_004431.1 2647811 2648593 R Escherichia coli K-12 ortholog: b2248; Escherichia coli O157:H7 ortholog: z3506; transcriptional regulator YfaX complement(2647811..2648593) Escherichia coli CFT073 1038312 NP_754677.1 CDS c2791 NC_004431.1 2648813 2650015 R Escherichia coli K-12 ortholog: b2249; Escherichia coli O157:H7 ortholog: z3507; competence damage-inducible protein A complement(2648813..2650015) Escherichia coli CFT073 1038313 NP_754678.1 CDS yfaZ NC_004431.1 2650115 2650678 R Escherichia coli K-12 ortholog: b2250; Escherichia coli O157:H7 ortholog: z3508; hypothetical protein complement(2650115..2650678) Escherichia coli CFT073 1038314 NP_754679.1 CDS yfaO NC_004431.1 2650936 2651361 D Escherichia coli K-12 ortholog: b2251; Escherichia coli O157:H7 ortholog: z3509; Nudix hydrolase yfaO 2650936..2651361 Escherichia coli CFT073 1038316 NP_754680.1 CDS ais NC_004431.1 2651400 2652029 R Escherichia coli K-12 ortholog: b2252; Escherichia coli O157:H7 ortholog: z3510; Ais protein complement(2651400..2652029) Escherichia coli CFT073 1038317 NP_754681.2 CDS yfbE NC_004431.1 2652310 2653449 D catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 2652310..2653449 Escherichia coli CFT073 1038318 NP_754682.1 CDS c2796 NC_004431.1 2653453 2654421 D catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase 2653453..2654421 Escherichia coli CFT073 1038319 NP_754683.1 CDS yfbG NC_004431.1 2654421 2656403 D Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 2654421..2656403 Escherichia coli CFT073 1038320 NP_754684.1 CDS yfbH NC_004431.1 2656400 2657290 D Escherichia coli K-12 ortholog: b2256; Escherichia coli O157:H7 ortholog: z3514; hypothetical protein 2656400..2657290 Escherichia coli CFT073 1038323 NP_754685.1 CDS arnT NC_004431.1 2657290 2658942 D catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 2657290..2658942 Escherichia coli CFT073 1038324 NP_754686.1 CDS c2800 NC_004431.1 2658939 2659274 D Escherichia coli O157:H7 ortholog: z3516; hypothetical protein 2658939..2659274 Escherichia coli CFT073 1038325 NP_754687.2 CDS yfbJ NC_004431.1 2659274 2659660 D Escherichia coli K-12 ortholog: b2258; Escherichia coli O157:H7 ortholog: z3517; hypothetical protein 2659274..2659660 Escherichia coli CFT073 1038326 NP_754688.1 CDS pmrD NC_004431.1 2659654 2659950 R Escherichia coli K-12 ortholog: b2259; Escherichia coli O157:H7 ortholog: z3519; polymyxin B resistance protein pmrD complement(2659654..2659950) Escherichia coli CFT073 1038329 NP_754689.1 CDS menE NC_004431.1 2660030 2661385 R Escherichia coli K-12 ortholog: b2260; Escherichia coli O157:H7 ortholog: z3520; O-succinylbenzoic acid--CoA ligase complement(2660030..2661385) Escherichia coli CFT073 1038331 NP_754690.1 CDS menC NC_004431.1 2661382 2662344 R catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase complement(2661382..2662344) Escherichia coli CFT073 1038332 NP_754691.1 CDS menB NC_004431.1 2662344 2663201 R catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase complement(2662344..2663201) Escherichia coli CFT073 1038333 NP_754692.1 CDS c2806 NC_004431.1 2662533 2663366 D hypothetical protein 2662533..2663366 Escherichia coli CFT073 1038334 NP_754693.1 CDS yfbB NC_004431.1 2663216 2663974 R catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase complement(2663216..2663974) Escherichia coli CFT073 1038335 NP_754694.2 CDS menD NC_004431.1 2663971 2665641 R SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase complement(2663971..2665641) Escherichia coli CFT073 1038336 NP_754695.1 CDS menF NC_004431.1 2665730 2667025 R synthesizes isochorismate acid from chorismate; menaquinone-specific isochorismate synthase complement(2665730..2667025) Escherichia coli CFT073 1038337 NP_754696.1 CDS elaB NC_004431.1 2667104 2667409 R Escherichia coli K-12 ortholog: b2266; Escherichia coli O157:H7 ortholog: z3526; hypothetical protein complement(2667104..2667409) Escherichia coli CFT073 1038338 NP_754697.1 CDS elaA NC_004431.1 2667464 2667925 R Escherichia coli K-12 ortholog: b2267; Escherichia coli O157:H7 ortholog: z3527; hypothetical protein complement(2667464..2667925) Escherichia coli CFT073 1038339 NP_754698.1 CDS elaC NC_004431.1 2667990 2668907 D member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 2667990..2668907 Escherichia coli CFT073 1038340 NP_754699.1 CDS yfbK NC_004431.1 2669028 2670770 R Escherichia coli K-12 ortholog: b2270; hypothetical protein complement(2669028..2670770) Escherichia coli CFT073 1038344 NP_754700.1 CDS c2814 NC_004431.1 2670902 2671024 D hypothetical protein 2670902..2671024 Escherichia coli CFT073 1038345 NP_754701.1 CDS yfbL NC_004431.1 2671062 2671880 D Escherichia coli K-12 ortholog: b2271; hypothetical protein 2671062..2671880 Escherichia coli CFT073 1038347 NP_754702.1 CDS yfbM NC_004431.1 2671983 2672486 D Escherichia coli K-12 ortholog: b2272; Escherichia coli O157:H7 ortholog: z3533; hypothetical protein 2671983..2672486 Escherichia coli CFT073 1038349 NP_754703.1 CDS nuoN NC_004431.1 2672553 2674010 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N complement(2672553..2674010) Escherichia coli CFT073 1038351 NP_754704.1 CDS nuoM NC_004431.1 2674017 2675546 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M complement(2674017..2675546) Escherichia coli CFT073 1038352 NP_754705.1 CDS nuoL NC_004431.1 2675710 2677551 R Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L complement(2675710..2677551) Escherichia coli CFT073 1038353 NP_754706.1 CDS nuoK NC_004431.1 2677548 2677850 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K complement(2677548..2677850) Escherichia coli CFT073 1038357 NP_754707.1 CDS nuoJ NC_004431.1 2677847 2678401 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J complement(2677847..2678401) Escherichia coli CFT073 1038358 NP_754708.1 CDS nuoI NC_004431.1 2678413 2678955 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I complement(2678413..2678955) Escherichia coli CFT073 1038361 NP_754709.1 CDS nuoH NC_004431.1 2678970 2679947 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H complement(2678970..2679947) Escherichia coli CFT073 1038362 NP_754710.1 CDS nuoG NC_004431.1 2679944 2682676 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G complement(2679944..2682676) Escherichia coli CFT073 1038363 NP_754711.1 CDS nuoF NC_004431.1 2682723 2684060 R shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F complement(2682723..2684060) Escherichia coli CFT073 1038364 NP_754712.1 CDS nuoE NC_004431.1 2684057 2684557 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E complement(2684057..2684557) Escherichia coli CFT073 1038365 NP_754713.1 CDS nuoC NC_004431.1 2684560 2686362 R NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D complement(2684560..2686362) Escherichia coli CFT073 1038366 NP_754714.1 CDS nuoB NC_004431.1 2686456 2687118 R The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B complement(2686456..2687118) Escherichia coli CFT073 1038369 NP_754715.1 CDS nuoA NC_004431.1 2687134 2687577 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A complement(2687134..2687577) Escherichia coli CFT073 1038370 NP_754716.1 CDS lrhA NC_004431.1 2688207 2689145 R Escherichia coli K-12 ortholog: b2289; Escherichia coli O157:H7 ortholog: z3549; transcriptional regulator lrhA complement(2688207..2689145) Escherichia coli CFT073 1038372 NP_754717.1 CDS c2831 NC_004431.1 2690065 2691282 D broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase 2690065..2691282 Escherichia coli CFT073 1038373 NP_754718.1 CDS yfbR NC_004431.1 2691366 2691965 D Escherichia coli K-12 ortholog: b2291; Escherichia coli O157:H7 ortholog: z3552; hypothetical protein 2691366..2691965 Escherichia coli CFT073 1038375 NP_754719.1 CDS yfbS NC_004431.1 2692024 2693856 R Escherichia coli K-12 ortholog: b2292; Escherichia coli O157:H7 ortholog: z3553; hypothetical protein complement(2692024..2693856) Escherichia coli CFT073 1038376 NP_754720.1 CDS yfbT NC_004431.1 2693943 2694593 R Escherichia coli K-12 ortholog: b2293; Escherichia coli O157:H7 ortholog: z3554; phosphatase complement(2693943..2694593) Escherichia coli CFT073 1038377 NP_754721.2 CDS c2835 NC_004431.1 2694604 2695098 R Escherichia coli K-12 ortholog: b2294; Escherichia coli O157:H7 ortholog: z3555; hypothetical protein complement(2694604..2695098) Escherichia coli CFT073 1038378 NP_754722.1 CDS yfbV NC_004431.1 2695180 2695635 R Escherichia coli K-12 ortholog: b2295; Escherichia coli O157:H7 ortholog: z3556; hypothetical protein complement(2695180..2695635) Escherichia coli CFT073 1038379 NP_754723.1 CDS c2837 NC_004431.1 2695704 2695835 R hypothetical protein complement(2695704..2695835) Escherichia coli CFT073 1038380 NP_754724.1 CDS ackA NC_004431.1 2695973 2697175 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 2695973..2697175 Escherichia coli CFT073 1038381 NP_754725.1 CDS c2839 NC_004431.1 2697178 2699448 R hypothetical protein complement(2697178..2699448) Escherichia coli CFT073 1038382 NP_754726.1 CDS pta NC_004431.1 2697250 2699394 D catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 2697250..2699394 Escherichia coli CFT073 1038383 NP_754727.2 CDS yfcC NC_004431.1 2699584 2701104 D Escherichia coli K-12 ortholog: b2298; Escherichia coli O157:H7 ortholog: z3560; hypothetical protein 2699584..2701104 Escherichia coli CFT073 1038386 NP_754728.1 CDS yfcD NC_004431.1 2701137 2701679 R Escherichia coli K-12 ortholog: b2299; Escherichia coli O157:H7 ortholog: z3561; hypothetical protein complement(2701137..2701679) Escherichia coli CFT073 1038387 NP_754729.1 CDS yfcE NC_004431.1 2701737 2702291 R Escherichia coli K-12 ortholog: b2300; Escherichia coli O157:H7 ortholog: z3562; phosphodiesterase complement(2701737..2702291) Escherichia coli CFT073 1038388 NP_754730.1 CDS yfcF NC_004431.1 2702344 2702988 R Escherichia coli K-12 ortholog: b2301; Escherichia coli O157:H7 ortholog: z3563; GST-like protein yfcF complement(2702344..2702988) Escherichia coli CFT073 1038389 NP_754731.1 CDS yfcG NC_004431.1 2703124 2703771 D Escherichia coli K-12 ortholog: b2302; Escherichia coli O157:H7 ortholog: z3564; glutathione S-transferase 2703124..2703771 Escherichia coli CFT073 1038392 NP_754732.1 CDS folX NC_004431.1 2703828 2704190 D catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 2703828..2704190 Escherichia coli CFT073 1038393 NP_754733.1 CDS yfcH NC_004431.1 2704211 2705104 D Escherichia coli K-12 ortholog: b2304; Escherichia coli O157:H7 ortholog: z3566; hypothetical protein 2704211..2705104 Escherichia coli CFT073 1038395 NP_754734.1 CDS hisP NC_004431.1 2705263 2706036 R Escherichia coli K-12 ortholog: b2306; Escherichia coli O157:H7 ortholog: z3568; histidine/lysine/arginine/ornithine transporter subunit complement(2705263..2706036) Escherichia coli CFT073 1038397 NP_754735.1 CDS hisM NC_004431.1 2706044 2706760 R Escherichia coli K-12 ortholog: b2307; Escherichia coli O157:H7 ortholog: z3569; histidine transport system permease hisM complement(2706044..2706760) Escherichia coli CFT073 1038399 NP_754736.1 CDS hisQ NC_004431.1 2706757 2707443 R Escherichia coli K-12 ortholog: b2308; Escherichia coli O157:H7 ortholog: z3570; histidine transport system permease hisQ complement(2706757..2707443) Escherichia coli CFT073 1038400 NP_754737.1 CDS hisJ NC_004431.1 2707533 2708315 R HBP; Escherichia coli K-12 ortholog: b2309; Escherichia coli O157:H7 ortholog: z3571; histidine-binding periplasmic protein complement(2707533..2708315) Escherichia coli CFT073 1038401 NP_754738.1 CDS c2854 NC_004431.1 2709463 2709606 R hypothetical protein complement(2709463..2709606) Escherichia coli CFT073 1038405 NP_754739.1 CDS ubiX NC_004431.1 2709584 2710153 R catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(2709584..2710153) Escherichia coli CFT073 1038407 NP_754740.1 CDS purF NC_004431.1 2710248 2711765 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(2710248..2711765) Escherichia coli CFT073 1038408 NP_754741.1 CDS cvpA NC_004431.1 2711802 2712290 R membrane protein required for colicin V production; colicin V production protein complement(2711802..2712290) Escherichia coli CFT073 1038409 NP_754742.1 CDS c2858 NC_004431.1 2712392 2712562 D Escherichia coli K-12 ortholog: b0100; hypothetical protein 2712392..2712562 Escherichia coli CFT073 1038412 NP_754743.2 CDS dedD NC_004431.1 2712822 2713484 R Escherichia coli K-12 ortholog: b2314; Escherichia coli O157:H7 ortholog: z3576; hypothetical protein complement(2712822..2713484) Escherichia coli CFT073 1038414 NP_754744.1 CDS folC NC_004431.1 2713474 2714742 R Escherichia coli K-12 ortholog: b2315; Escherichia coli O157:H7 ortholog: z3577; bifunctional; bifunctional folylpolyglutamate synthase/ dihydrofolate synthase complement(2713474..2714742) Escherichia coli CFT073 1038415 NP_754745.2 CDS accD NC_004431.1 2714812 2715726 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta complement(2714812..2715726) Escherichia coli CFT073 1038416 NP_754746.1 CDS dedA NC_004431.1 2715882 2716541 R DSG-1 protein; Escherichia coli K-12 ortholog: b2317; Escherichia coli O157:H7 ortholog: z3579; hypothetical protein complement(2715882..2716541) Escherichia coli CFT073 1038417 NP_754747.1 CDS truA NC_004431.1 2716624 2717436 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(2716624..2717436) Escherichia coli CFT073 1038418 NP_754748.1 CDS usg NC_004431.1 2717436 2718449 R Escherichia coli K-12 ortholog: b2319; Escherichia coli O157:H7 ortholog: z3581; semialdehyde dehydrogenase complement(2717436..2718449) Escherichia coli CFT073 1038419 NP_754749.1 CDS pdxB NC_004431.1 2718515 2719651 R catalyzes the formation of 3-hydroxy-4-phospho-hydroxy-alpha-ketobutyrate from erythronate-4-phosphate; erythronate-4-phosphate dehydrogenase complement(2718515..2719651) Escherichia coli CFT073 1038420 NP_754750.1 CDS flk NC_004431.1 2719750 2720745 D in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 2719750..2720745 Escherichia coli CFT073 1038421 NP_754751.1 CDS fabB NC_004431.1 2722183 2723403 R FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase complement(2722183..2723403) Escherichia coli CFT073 1038429 NP_754752.2 CDS mnmC NC_004431.1 2723562 2725568 D catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 2723562..2725568 Escherichia coli CFT073 1038430 NP_754753.1 CDS yfcL NC_004431.1 2725689 2725967 R Escherichia coli K-12 ortholog: b2325; Escherichia coli O157:H7 ortholog: z3588; hypothetical protein complement(2725689..2725967) Escherichia coli CFT073 1038431 NP_754754.1 CDS yfcM NC_004431.1 2726001 2726549 R Escherichia coli K-12 ortholog: b2326; Escherichia coli O157:H7 ortholog: z3589; hypothetical protein complement(2726001..2726549) Escherichia coli CFT073 1038433 NP_754755.1 CDS yfcA NC_004431.1 2726549 2727358 R Escherichia coli K-12 ortholog: b2327; Escherichia coli O157:H7 ortholog: z3590; hypothetical protein complement(2726549..2727358) Escherichia coli CFT073 1038435 NP_754756.1 CDS mepA NC_004431.1 2727358 2728182 R D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase complement(2727358..2728182) Escherichia coli CFT073 1038436 NP_754757.1 CDS aroC NC_004431.1 2728186 2729274 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(2728186..2729274) Escherichia coli CFT073 1038437 NP_754758.1 CDS yfcB NC_004431.1 2729306 2730571 R involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(2729306..2730571) Escherichia coli CFT073 1038438 NP_754759.1 CDS yfcN NC_004431.1 2730404 2730955 D Escherichia coli K-12 ortholog: b2331; Escherichia coli O157:H7 ortholog: z3594; hypothetical protein 2730404..2730955 Escherichia coli CFT073 1038439 NP_754760.1 CDS yfcO NC_004431.1 2731275 2732147 R Escherichia coli K-12 ortholog: b2332; Escherichia coli O157:H7 ortholog: z3595; hypothetical protein complement(2731275..2732147) Escherichia coli CFT073 1038440 NP_754761.1 CDS yfcP NC_004431.1 2732134 2732661 R Escherichia coli K-12 ortholog: b2333; Escherichia coli O157:H7 ortholog: z3596; fimbrial-like protein yfcP complement(2732134..2732661) Escherichia coli CFT073 1038441 NP_754762.1 CDS yfcQ NC_004431.1 2732658 2733137 R Escherichia coli K-12 ortholog: b2334; Escherichia coli O157:H7 ortholog: z3597; fimbrial-like protein yfcQ complement(2732658..2733137) Escherichia coli CFT073 1038442 NP_754763.1 CDS yfcR NC_004431.1 2733134 2733637 R Escherichia coli K-12 ortholog: b2335; Escherichia coli O157:H7 ortholog: z3598; hypothetical protein complement(2733134..2733637) Escherichia coli CFT073 1038443 NP_754764.1 CDS yfcS NC_004431.1 2733654 2734406 R Escherichia coli K-12 ortholog: b2336; Escherichia coli O157:H7 ortholog: z3599; fimbrial chaperone yfcS complement(2733654..2734406) Escherichia coli CFT073 1038445 NP_754765.1 CDS yfcU NC_004431.1 2734426 2737080 R Escherichia coli K-12 ortholog: b2338; Escherichia coli O157:H7 ortholog: z3600; hypothetical protein complement(2734426..2737080) Escherichia coli CFT073 1038446 NP_754766.1 CDS yfcV NC_004431.1 2737155 2737721 R Escherichia coli K-12 ortholog: b2339; Escherichia coli O157:H7 ortholog: z3601; fimbrial-like protein yfcV complement(2737155..2737721) Escherichia coli CFT073 1038447 NP_754767.1 CDS c2885 NC_004431.1 2738288 2738773 R Escherichia coli K-12 ortholog: b2340; Escherichia coli O157:H7 ortholog: z3603; phosphohistidine phosphatase complement(2738288..2738773) Escherichia coli CFT073 1038448 NP_754768.1 CDS fadJ NC_004431.1 2738976 2741120 R multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha complement(2738976..2741120) Escherichia coli CFT073 1038451 NP_754769.1 CDS fadI NC_004431.1 2741120 2742430 R FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase complement(2741120..2742430) Escherichia coli CFT073 1038455 NP_754770.1 CDS yfcZ NC_004431.1 2742610 2742918 R Escherichia coli K-12 ortholog: b2343; Escherichia coli O157:H7 ortholog: z3606; hypothetical protein complement(2742610..2742918) Escherichia coli CFT073 1038456 NP_754771.1 CDS fadL NC_004431.1 2743260 2744606 D Outer membrane FADL protein; Escherichia coli K-12 ortholog: b2344; Escherichia coli O157:H7 ortholog: z3608; long-chain fatty acid outer membrane transporter 2743260..2744606 Escherichia coli CFT073 1038457 NP_754772.1 CDS vacJ NC_004431.1 2744668 2745423 R Escherichia coli K-12 ortholog: b2346; Escherichia coli O157:H7 ortholog: z3610; VacJ lipoprotein complement(2744668..2745423) Escherichia coli CFT073 1038459 NP_754773.1 CDS c2891 NC_004431.1 2745449 2745619 R hypothetical protein complement(2745449..2745619) Escherichia coli CFT073 1038461 NP_754774.1 CDS yfdC NC_004431.1 2745717 2746649 D Escherichia coli K-12 ortholog: b2347; Escherichia coli O157:H7 ortholog: z3611; hypothetical protein 2745717..2746649 Escherichia coli CFT073 1038462 NP_754775.1 CDS c2893 NC_004431.1 2747237 2747767 R hypothetical protein complement(2747237..2747767) Escherichia coli CFT073 1038464 NP_754776.1 CDS ydeU NC_004431.1 2747815 2748690 R Escherichia coli K-12 ortholog: b1509; hypothetical protein complement(2747815..2748690) Escherichia coli CFT073 1038466 NP_754777.1 CDS c2895 NC_004431.1 2748603 2755766 R Residues 45 to 1255 of 2387 are 21.57 pct identical to residues 2499 to 3684 of 3705 from GenPept.129 : >emb|CAC89847.1| (AJ414146) autotransporter protein [Yersinia pestis]; yapH-like protein complement(2748603..2755766) Escherichia coli CFT073 1038467 NP_754778.1 CDS c2896 NC_004431.1 2755791 2756411 R hypothetical protein complement(2755791..2756411) Escherichia coli CFT073 1038470 NP_754779.1 CDS c2897 NC_004431.1 2756729 2757358 R Escherichia coli K-12 ortholog: b4312; Escherichia coli O157:H7 ortholog: z5910; Type 1 fimbriae regulatory protein fimB complement(2756729..2757358) Escherichia coli CFT073 1038471 NP_754780.1 CDS c2898 NC_004431.1 2758106 2758675 D Escherichia coli K-12 ortholog: b4312; Escherichia coli O157:H7 ortholog: z5910; Type 1 fimbriae regulatory protein fimB 2758106..2758675 Escherichia coli CFT073 1038472 NP_754781.1 CDS dsdC NC_004431.1 2759070 2760023 R regulates the synthesis and expression of the dsdXA operon and dadA gene; DNA-binding transcriptional regulator DsdC complement(2759070..2760023) Escherichia coli CFT073 1038477 NP_754782.1 CDS dsdX NC_004431.1 2760235 2761572 D member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; permease DsdX 2760235..2761572 Escherichia coli CFT073 1038478 NP_754783.1 CDS dsdA NC_004431.1 2761590 2762918 D catalyzes the formation of pyruvate from serine; D-serine dehydratase 2761590..2762918 Escherichia coli CFT073 1038480 NP_754784.1 CDS emrY NC_004431.1 2763026 2764564 R Escherichia coli K-12 ortholog: b2367; Escherichia coli O157:H7 ortholog: z3629; multidrug resistance protein Y complement(2763026..2764564) Escherichia coli CFT073 1038481 NP_754785.1 CDS c2903 NC_004431.1 2764251 2764589 D hypothetical protein 2764251..2764589 Escherichia coli CFT073 1038483 NP_754786.1 CDS emrK NC_004431.1 2764564 2765727 R Escherichia coli K-12 ortholog: b2368; Escherichia coli O157:H7 ortholog: z3630; multidrug resistance protein K complement(2764564..2765727) Escherichia coli CFT073 1038484 NP_754787.1 CDS evgA NC_004431.1 2766143 2766757 D response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; DNA-binding transcriptional activator EvgA 2766143..2766757 Escherichia coli CFT073 1038485 NP_754788.1 CDS evgS NC_004431.1 2766762 2770355 D Escherichia coli K-12 ortholog: b2370; Escherichia coli O157:H7 ortholog: z3632; hybrid sensory histidine kinase in two-component regulatory system with EvgA 2766762..2770355 Escherichia coli CFT073 1038486 NP_754789.1 CDS yfdE NC_004431.1 2770411 2771595 R Escherichia coli K-12 ortholog: b2371; Escherichia coli O157:H7 ortholog: z3633; hypothetical protein complement(2770411..2771595) Escherichia coli CFT073 1038487 NP_754790.1 CDS yfdV NC_004431.1 2771630 2772574 R member of the AEC family of auxin efflux transporters; unknown function; transporter YfdV complement(2771630..2772574) Escherichia coli CFT073 1038492 NP_754791.1 CDS c2909 NC_004431.1 2772644 2774338 R catalyzes the formation of formyl-CoA from oxalyl-CoA; oxalyl-CoA decarboxylase complement(2772644..2774338) Escherichia coli CFT073 1038493 NP_754792.1 CDS yfdW NC_004431.1 2774392 2775642 R catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase complement(2774392..2775642) Escherichia coli CFT073 1038494 NP_754793.1 CDS c2911 NC_004431.1 2776154 2776786 R Escherichia coli K-12 ortholog: b2375; Escherichia coli O157:H7 ortholog: z3640; hypothetical protein complement(2776154..2776786) Escherichia coli CFT073 1038495 NP_754794.1 CDS ypdI NC_004431.1 2777081 2777356 D Escherichia coli K-12 ortholog: b2376; Escherichia coli O157:H7 ortholog: z3641; lipoprotein ypdI 2777081..2777356 Escherichia coli CFT073 1038499 NP_754795.1 CDS c2913 NC_004431.1 2777341 2777478 R hypothetical protein complement(2777341..2777478) Escherichia coli CFT073 1038500 NP_754796.1 CDS yfdY NC_004431.1 2777433 2777675 R Escherichia coli K-12 ortholog: b2377; Escherichia coli O157:H7 ortholog: z3642; hypothetical protein complement(2777433..2777675) Escherichia coli CFT073 1038503 NP_754797.2 CDS ddg NC_004431.1 2778028 2778948 D Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 2778028..2778948 Escherichia coli CFT073 1038504 NP_754798.1 CDS yfdZ NC_004431.1 2779440 2780678 R Escherichia coli K-12 ortholog: b2379; Escherichia coli O157:H7 ortholog: z3644; aminotransferase complement(2779440..2780678) Escherichia coli CFT073 1038505 NP_754799.1 CDS c2917 NC_004431.1 2780597 2780728 R hypothetical protein complement(2780597..2780728) Escherichia coli CFT073 1038508 NP_754800.1 CDS c2918 NC_004431.1 2780865 2781002 R hypothetical protein complement(2780865..2781002) Escherichia coli CFT073 1038511 NP_754801.1 CDS ypdA NC_004431.1 2781054 2782751 D Escherichia coli K-12 ortholog: b2380; Escherichia coli O157:H7 ortholog: z3645; hypothetical protein 2781054..2782751 Escherichia coli CFT073 1038513 NP_754802.1 CDS ypdB NC_004431.1 2782748 2783503 D Escherichia coli K-12 ortholog: b2381; Escherichia coli O157:H7 ortholog: z3646; hypothetical protein 2782748..2783503 Escherichia coli CFT073 1038514 NP_754803.1 CDS ypdC NC_004431.1 2783516 2784373 D Escherichia coli K-12 ortholog: b2382; Escherichia coli O157:H7 ortholog: z3647; transcriptional regulator YpdC 2783516..2784373 Escherichia coli CFT073 1038515 NP_754804.1 CDS c2922 NC_004431.1 2784376 2786871 R Escherichia coli K-12 ortholog: b2383; Escherichia coli O157:H7 ortholog: z3648; phosphoenolpyruvate-protein phosphotransferase ypdD complement(2784376..2786871) Escherichia coli CFT073 1038516 NP_754805.1 CDS ypdE NC_004431.1 2786896 2787933 R metalloprotein; exoaminopeptidase complement(2786896..2787933) Escherichia coli CFT073 1038519 NP_754806.1 CDS c2924 NC_004431.1 2787933 2789018 R Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase complement(2787933..2789018) Escherichia coli CFT073 1038523 NP_754807.1 CDS c2925 NC_004431.1 2789034 2790281 R Escherichia coli K-12 ortholog: b2386; Escherichia coli O157:H7 ortholog: z3652; PTS system IIC component ypdG complement(2789034..2790281) Escherichia coli CFT073 1038524 NP_754808.1 CDS c2926 NC_004431.1 2790303 2790680 R Escherichia coli K-12 ortholog: b2387; Escherichia coli O157:H7 ortholog: z3653; PTS system IIB component ypdH complement(2790303..2790680) Escherichia coli CFT073 1038525 NP_754809.1 CDS glk NC_004431.1 2790848 2791813 R catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase complement(2790848..2791813) Escherichia coli CFT073 1038526 NP_754810.1 CDS yfeO NC_004431.1 2792017 2793273 D Escherichia coli K-12 ortholog: b2389; Escherichia coli O157:H7 ortholog: z3655; hypothetical protein 2792017..2793273 Escherichia coli CFT073 1038527 NP_754811.1 CDS ypeC NC_004431.1 2793388 2793714 D Escherichia coli K-12 ortholog: b2390; Escherichia coli O157:H7 ortholog: z3656; hypothetical protein 2793388..2793714 Escherichia coli CFT073 1038529 YP_004853816.1 CDS c2930 NC_004431.1 2793437 2793796 D hypothetical protein 2793437..2793796 Escherichia coli CFT073 1038530 NP_754813.1 CDS c2931 NC_004431.1 2793855 2795093 R Escherichia coli K-12 ortholog: b2392; Escherichia coli O157:H7 ortholog: z3658; manganese transport protein MntH complement(2793855..2795093) Escherichia coli CFT073 1038531 NP_754814.1 CDS nupC NC_004431.1 2795390 2796631 D Nucleoside-transport system protein nupC; Escherichia coli K-12 ortholog: b2393; Escherichia coli O157:H7 ortholog: z3659; nucleoside permease nupC 2795390..2796631 Escherichia coli CFT073 1038532 NP_754815.1 CDS yfeA NC_004431.1 2796680 2798929 R Escherichia coli K-12 ortholog: b2395; Escherichia coli O157:H7 ortholog: z3660; hypothetical protein complement(2796680..2798929) Escherichia coli CFT073 1038533 NP_754816.1 CDS yfeC NC_004431.1 2799487 2799846 D Escherichia coli K-12 ortholog: b2398; Escherichia coli O157:H7 ortholog: z3662; hypothetical protein 2799487..2799846 Escherichia coli CFT073 1038539 NP_754817.1 CDS yfeD NC_004431.1 2799848 2800240 D Escherichia coli K-12 ortholog: b2399; Escherichia coli O157:H7 ortholog: z3663; hypothetical protein 2799848..2800240 Escherichia coli CFT073 1038540 NP_754818.1 CDS gltX NC_004431.1 2800291 2801706 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(2800291..2801706) Escherichia coli CFT073 1038541 NP_754819.1 CDS xapR NC_004431.1 2802472 2803371 R Escherichia coli K-12 ortholog: b2405; DNA-binding transcriptional activator XapR complement(2802472..2803371) Escherichia coli CFT073 1038559 NP_754820.1 CDS c2938 NC_004431.1 2803397 2803555 R Residues 1 to 52 of 52 are 40.38 pct identical to residues 1 to 52 of 53 from GenPept.129 : >dbj|BAB07525.1| (AP001520) BH3806; unknown [Bacillus halodurans]; hypothetical protein complement(2803397..2803555) Escherichia coli CFT073 1038561 NP_754821.1 CDS xapB NC_004431.1 2803608 2804864 R Xanthosine transporter; Escherichia coli K-12 ortholog: b2406; Escherichia coli O157:H7 ortholog: z4309; xanthosine permease complement(2803608..2804864) Escherichia coli CFT073 1038563 NP_754822.1 CDS xapA NC_004431.1 2804925 2805758 R catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase complement(2804925..2805758) Escherichia coli CFT073 1038564 NP_754823.2 CDS yfeN NC_004431.1 2806006 2806770 D Escherichia coli K-12 ortholog: b2408; hypothetical protein 2806006..2806770 Escherichia coli CFT073 1038565 NP_754824.1 CDS yfeR NC_004431.1 2806809 2807735 R Escherichia coli K-12 ortholog: b2409; transcriptional regulator YfeR complement(2806809..2807735) Escherichia coli CFT073 1038566 NP_754825.1 CDS yfeH NC_004431.1 2807825 2808823 D Escherichia coli K-12 ortholog: b2410; Escherichia coli O157:H7 ortholog: z3675; hypothetical protein 2807825..2808823 Escherichia coli CFT073 1038570 NP_754826.1 CDS c2944 NC_004431.1 2808820 2809038 R Escherichia coli O157:H7 ortholog: z3676; hypothetical protein complement(2808820..2809038) Escherichia coli CFT073 1038575 NP_754827.1 CDS ligA NC_004431.1 2809040 2811055 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(2809040..2811055) Escherichia coli CFT073 1038577 NP_754828.1 CDS zipA NC_004431.1 2811126 2812175 R interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA complement(2811126..2812175) Escherichia coli CFT073 1038578 NP_754829.1 CDS cysZ NC_004431.1 2812354 2813115 D role in sulfur assimilation; sulfate transport protein CysZ 2812354..2813115 Escherichia coli CFT073 1038579 NP_754830.1 CDS cysK NC_004431.1 2813300 2814283 D CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 2813300..2814283 Escherichia coli CFT073 1038580 NP_754831.1 CDS c2949 NC_004431.1 2814394 2814519 R hypothetical protein complement(2814394..2814519) Escherichia coli CFT073 1038582 NP_754832.1 CDS ptsH NC_004431.1 2814656 2814913 D Histidine-containing protein; Escherichia coli K-12 ortholog: b2415; Escherichia coli O157:H7 ortholog: z3681; PTS system phosphohistidinoprotein-hexose phosphotransferase subunit Hpr 2814656..2814913 Escherichia coli CFT073 1038584 NP_754833.1 CDS ptsI NC_004431.1 2815190 2816686 D Escherichia coli K-12 ortholog: b2416; Escherichia coli O157:H7 ortholog: z3682; phosphoenolpyruvate-protein phosphotransferase 2815190..2816686 Escherichia coli CFT073 1038585 NP_754834.1 CDS crr NC_004431.1 2816727 2817236 D functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter subunit 2816727..2817236 Escherichia coli CFT073 1038586 NP_754835.1 CDS pdxK NC_004431.1 2817279 2818130 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase complement(2817279..2818130) Escherichia coli CFT073 1038587 NP_754836.1 CDS yfeK NC_004431.1 2818235 2818603 D Escherichia coli K-12 ortholog: b2419; Escherichia coli O157:H7 ortholog: z3685; hypothetical protein 2818235..2818603 Escherichia coli CFT073 1038588 NP_754837.1 CDS cysM NC_004431.1 2818606 2819517 R catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B complement(2818606..2819517) Escherichia coli CFT073 1038591 NP_754838.1 CDS cysA NC_004431.1 2819652 2820749 R Escherichia coli K-12 ortholog: b2422; Escherichia coli O157:H7 ortholog: z3687; sulfate/thiosulfate transporter subunit complement(2819652..2820749) Escherichia coli CFT073 1038592 NP_754839.1 CDS cysW NC_004431.1 2820739 2821614 R Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit complement(2820739..2821614) Escherichia coli CFT073 1038593 NP_754840.1 CDS cysU NC_004431.1 2821614 2822447 R Escherichia coli K-12 ortholog: b2424; Escherichia coli O157:H7 ortholog: z3689; sulfate/thiosulfate transporter subunit complement(2821614..2822447) Escherichia coli CFT073 1038594 NP_754841.1 CDS cysP NC_004431.1 2822447 2823463 R Escherichia coli K-12 ortholog: b2425; Escherichia coli O157:H7 ortholog: z3690; thiosulfate transporter subunit complement(2822447..2823463) Escherichia coli CFT073 1038596 NP_754842.2 CDS ucpA NC_004431.1 2823621 2824412 R Escherichia coli K-12 ortholog: b2426; Escherichia coli O157:H7 ortholog: z3691; short chain dehydrogenase complement(2823621..2824412) Escherichia coli CFT073 1038597 NP_754843.1 CDS murQ NC_004431.1 2824692 2825588 D catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase 2824692..2825588 Escherichia coli CFT073 1038598 NP_754844.1 CDS murP NC_004431.1 2825592 2827016 D belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunits EIIBC 2825592..2827016 Escherichia coli CFT073 1038599 NP_754845.1 CDS c2963 NC_004431.1 2827036 2827179 R hypothetical protein complement(2827036..2827179) Escherichia coli CFT073 1038601 NP_754846.1 CDS c2964 NC_004431.1 2827179 2828105 D hypothetical protein 2827179..2828105 Escherichia coli CFT073 1038603 NP_754847.1 CDS yfeX NC_004431.1 2827194 2828120 R Escherichia coli K-12 ortholog: b2431; Escherichia coli O157:H7 ortholog: z3696; hypothetical protein complement(2827194..2828120) Escherichia coli CFT073 1038605 NP_754848.1 CDS yfeY NC_004431.1 2828189 2828764 R Escherichia coli K-12 ortholog: b2432; Escherichia coli O157:H7 ortholog: z3697; hypothetical protein complement(2828189..2828764) Escherichia coli CFT073 1038607 NP_754849.1 CDS yfeZ NC_004431.1 2828825 2829280 R Escherichia coli K-12 ortholog: b2433; Escherichia coli O157:H7 ortholog: z3698; hypothetical protein complement(2828825..2829280) Escherichia coli CFT073 1038608 NP_754850.2 CDS ypeA NC_004431.1 2829261 2829686 R Escherichia coli K-12 ortholog: b2434; Escherichia coli O157:H7 ortholog: z3699; acetyltransferase complement(2829261..2829686) Escherichia coli CFT073 1038610 NP_754851.1 CDS amiA NC_004431.1 2829900 2830769 D Escherichia coli K-12 ortholog: b2435; Escherichia coli O157:H7 ortholog: z3700; N-acetylmuramoyl-L-alanine amidase 2829900..2830769 Escherichia coli CFT073 1038611 NP_754852.1 CDS hemF NC_004431.1 2830770 2831672 D catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 2830770..2831672 Escherichia coli CFT073 1038612 NP_754853.1 CDS yfeG NC_004431.1 2831678 2832730 R activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR complement(2831678..2832730) Escherichia coli CFT073 1038613 NP_754854.1 CDS c2972 NC_004431.1 2832776 2833282 R Escherichia coli K-12 ortholog: b2438; Escherichia coli O157:H7 ortholog: z3703; ethanolamine utilization protein EutK complement(2832776..2833282) Escherichia coli CFT073 1038614 NP_754855.1 CDS c2973 NC_004431.1 2833289 2833948 R Escherichia coli K-12 ortholog: b2439; Escherichia coli O157:H7 ortholog: z3704; ethanolamine utilization protein EutL complement(2833289..2833948) Escherichia coli CFT073 1038615 NP_754856.1 CDS eutC NC_004431.1 2833958 2834845 R catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit complement(2833958..2834845) Escherichia coli CFT073 1038616 NP_754857.1 CDS eutB NC_004431.1 2834866 2836227 R Escherichia coli K-12 ortholog: b2441; Escherichia coli O157:H7 ortholog: z3706; ethanolamine ammonia-lyase heavy chain complement(2834866..2836227) Escherichia coli CFT073 1038619 NP_754858.1 CDS eutA NC_004431.1 2836239 2837642 R ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase complement(2836239..2837642) Escherichia coli CFT073 1038620 NP_754859.1 CDS eutH NC_004431.1 2837639 2838865 R ethanolamine transporter; Escherichia coli K-12 ortholog: b2452; Escherichia coli O157:H7 ortholog: z3708; ethanolamine utilization protein EutH complement(2837639..2838865) Escherichia coli CFT073 1038621 NP_754860.1 CDS eutG NC_004431.1 2839082 2840296 R Escherichia coli K-12 ortholog: b2453; Escherichia coli O157:H7 ortholog: z3709; ethanolamine utilization protein EutG complement(2839082..2840296) Escherichia coli CFT073 1038622 NP_754861.1 CDS eutJ NC_004431.1 2840259 2841095 R Escherichia coli K-12 ortholog: b2454; Escherichia coli O157:H7 ortholog: z3710; ethanolamine utilization protein EutJ complement(2840259..2841095) Escherichia coli CFT073 1038624 NP_754862.1 CDS eutE NC_004431.1 2841106 2842509 R Escherichia coli K-12 ortholog: b2455; Escherichia coli O157:H7 ortholog: z3711; ethanolamine utilization protein EutE complement(2841106..2842509) Escherichia coli CFT073 1038626 NP_754863.1 CDS cchB NC_004431.1 2842521 2842808 R Escherichia coli K-12 ortholog: b2456; Escherichia coli O157:H7 ortholog: z3712; ethanolamine utilization protein EutN complement(2842521..2842808) Escherichia coli CFT073 1038627 NP_754864.2 CDS cchA NC_004431.1 2842915 2843208 R Escherichia coli K-12 ortholog: b2457; Escherichia coli O157:H7 ortholog: z3713; ethanolamine utilization protein EutM complement(2842915..2843208) Escherichia coli CFT073 1038628 NP_754865.1 CDS eutD NC_004431.1 2843247 2844263 R in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase complement(2843247..2844263) Escherichia coli CFT073 1038630 NP_754866.1 CDS c2984 NC_004431.1 2844260 2845063 R Escherichia coli K-12 ortholog: b2459; Escherichia coli O157:H7 ortholog: z3715; ethanolamine utilization cobalamin adenosyltransferase complement(2844260..2845063) Escherichia coli CFT073 1038632 NP_754867.1 CDS c2985 NC_004431.1 2845060 2845761 R Escherichia coli K-12 ortholog: b2460; Escherichia coli O157:H7 ortholog: z3716; ethanolamine utilization protein EutQ complement(2845060..2845761) Escherichia coli CFT073 1038633 NP_754868.1 CDS c2986 NC_004431.1 2845736 2846215 R Escherichia coli K-12 ortholog: b2461; Escherichia coli O157:H7 ortholog: z3717; ethanolamine utilization protein EutP complement(2845736..2846215) Escherichia coli CFT073 1038634 NP_754869.1 CDS c2987 NC_004431.1 2846228 2846635 R Escherichia coli K-12 ortholog: b2462; Escherichia coli O157:H7 ortholog: z3718; ethanolamine utilization protein EutS complement(2846228..2846635) Escherichia coli CFT073 1038635 NP_754870.1 CDS c2988 NC_004431.1 2846856 2849135 R NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme complement(2846856..2849135) Escherichia coli CFT073 1038636 NP_754871.1 CDS talA NC_004431.1 2849424 2850374 D Maintains the balance of metabolites in the pentose-phosphate pathway; transaldolase A 2849424..2850374 Escherichia coli CFT073 1038637 NP_754872.2 CDS tktB NC_004431.1 2850394 2852397 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2850394..2852397 Escherichia coli CFT073 1038638 NP_754873.1 CDS ypfG NC_004431.1 2852500 2853543 R Escherichia coli K-12 ortholog: b2466; Escherichia coli O157:H7 ortholog: z3722; hypothetical protein complement(2852500..2853543) Escherichia coli CFT073 1038640 NP_754874.1 CDS c2992 NC_004431.1 2853437 2853568 R hypothetical protein complement(2853437..2853568) Escherichia coli CFT073 1038641 NP_754875.1 CDS c2993 NC_004431.1 2853443 2853703 D hypothetical protein 2853443..2853703 Escherichia coli CFT073 1038643 NP_754876.1 CDS yffH NC_004431.1 2853669 2854271 R Escherichia coli K-12 ortholog: b2467; Escherichia coli O157:H7 ortholog: z3723; hypothetical protein complement(2853669..2854271) Escherichia coli CFT073 1038644 NP_754877.1 CDS yffG NC_004431.1 2854312 2856291 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit complement(2854312..2856291) Escherichia coli CFT073 1038647 NP_754878.1 CDS narQ NC_004431.1 2856482 2858197 D Escherichia coli K-12 ortholog: b2469; Escherichia coli O157:H7 ortholog: z3726; nitrate/nitrite sensor protein NarQ 2856482..2858197 Escherichia coli CFT073 1038649 NP_754879.1 CDS acrD NC_004431.1 2858361 2861474 D Acriflavine resistance protein D; Escherichia coli K-12 ortholog: b2470; Escherichia coli O157:H7 ortholog: z3727; aminoglycoside/multidrug efflux system 2858361..2861474 Escherichia coli CFT073 1038650 NP_754880.1 CDS yffB NC_004431.1 2862013 2862369 D Escherichia coli K-12 ortholog: b2471; Escherichia coli O157:H7 ortholog: z3729; hypothetical protein 2862013..2862369 Escherichia coli CFT073 1038652 NP_754881.1 CDS dapE NC_004431.1 2862373 2863500 D dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2862373..2863500 Escherichia coli CFT073 1038653 NP_754882.1 CDS c3000 NC_004431.1 2863528 2863728 D Escherichia coli O157:H7 ortholog: z3731; hypothetical protein 2863528..2863728 Escherichia coli CFT073 1038654 NP_754883.2 CDS ypfH NC_004431.1 2863809 2864507 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase complement(2863809..2864507) Escherichia coli CFT073 1038655 NP_754884.1 CDS ypfI NC_004431.1 2864581 2866596 R Escherichia coli K-12 ortholog: b2474; Escherichia coli O157:H7 ortholog: z3733; hypothetical protein complement(2864581..2866596) Escherichia coli CFT073 1038656 NP_754885.1 CDS ypfJ NC_004431.1 2866611 2867474 R Escherichia coli K-12 ortholog: b2475; Escherichia coli O157:H7 ortholog: z3734; hypothetical protein complement(2866611..2867474) Escherichia coli CFT073 1038657 NP_754886.1 CDS purC NC_004431.1 2867642 2868364 R catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase complement(2867642..2868364) Escherichia coli CFT073 1038660 NP_754887.1 CDS nlpB NC_004431.1 2868568 2869605 R Escherichia coli K-12 ortholog: b2477; Escherichia coli O157:H7 ortholog: z3736; lipoprotein complement(2868568..2869605) Escherichia coli CFT073 1038661 NP_754888.1 CDS dapA NC_004431.1 2869619 2870515 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(2869619..2870515) Escherichia coli CFT073 1038664 NP_754889.2 CDS gcvR NC_004431.1 2870643 2871215 D negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 2870643..2871215 Escherichia coli CFT073 1038665 NP_754890.1 CDS bcp NC_004431.1 2871215 2871685 D bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 2871215..2871685 Escherichia coli CFT073 1038668 NP_754891.1 CDS perM NC_004431.1 2871784 2872845 R Escherichia coli K-12 ortholog: b2493; Escherichia coli O157:H7 ortholog: z3755; permease PerM complement(2871784..2872845) Escherichia coli CFT073 1038669 NP_754892.1 CDS c3010 NC_004431.1 2872876 2873052 D hypothetical protein 2872876..2873052 Escherichia coli CFT073 1038670 NP_754893.1 CDS yfgC NC_004431.1 2873058 2874521 D Escherichia coli K-12 ortholog: b2494; Escherichia coli O157:H7 ortholog: z3757; hypothetical protein 2873058..2874521 Escherichia coli CFT073 1038674 NP_754894.1 CDS c3012 NC_004431.1 2874542 2874901 D Escherichia coli K-12 ortholog: b2495; Escherichia coli O157:H7 ortholog: z3758; hypothetical protein 2874542..2874901 Escherichia coli CFT073 1038675 NP_754895.1 CDS yfgE NC_004431.1 2875039 2875785 R controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor complement(2875039..2875785) Escherichia coli CFT073 1038677 NP_754896.1 CDS uraA NC_004431.1 2875835 2877166 R Uracil transporter; Escherichia coli K-12 ortholog: b2497; Escherichia coli O157:H7 ortholog: z3760; uracil transporter complement(2875835..2877166) Escherichia coli CFT073 1038679 NP_754897.2 CDS upp NC_004431.1 2877210 2877836 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(2877210..2877836) Escherichia coli CFT073 1038680 NP_754898.1 CDS c3016 NC_004431.1 2877798 2878142 D hypothetical protein 2877798..2878142 Escherichia coli CFT073 1038681 NP_754899.1 CDS purM NC_004431.1 2878161 2879198 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 2878161..2879198 Escherichia coli CFT073 1038683 NP_754900.1 CDS purN NC_004431.1 2879198 2879836 D glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 2879198..2879836 Escherichia coli CFT073 1038684 NP_754901.1 CDS ppk NC_004431.1 2880002 2882074 D catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 2880002..2882074 Escherichia coli CFT073 1038685 NP_754902.1 CDS ppx NC_004431.1 2882079 2883620 D Escherichia coli K-12 ortholog: b2502; Escherichia coli O157:H7 ortholog: z3765; exopolyphosphatase 2882079..2883620 Escherichia coli CFT073 1038687 NP_754903.1 CDS yfgF NC_004431.1 2883659 2885902 R Escherichia coli K-12 ortholog: b2503; Escherichia coli O157:H7 ortholog: z3766; hypothetical protein complement(2883659..2885902) Escherichia coli CFT073 1038688 NP_754904.1 CDS c3022 NC_004431.1 2886084 2886236 R Escherichia coli O157:H7 ortholog: z3767; hypothetical protein complement(2886084..2886236) Escherichia coli CFT073 1038689 NP_754905.1 CDS c3023 NC_004431.1 2886119 2886409 R Residues 2 to 63 of 96 are 69.35 pct identical to residues 1 to 62 of 86 from GenPept.129 : >gb|AAL21399.1| (AE008813) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein complement(2886119..2886409) Escherichia coli CFT073 1038690 NP_754906.1 CDS yfgH NC_004431.1 2886756 2887274 D Escherichia coli K-12 ortholog: b2505; Escherichia coli O157:H7 ortholog: z3769; lipoprotein yfgH 2886756..2887274 Escherichia coli CFT073 1038693 NP_754907.1 CDS yfgI NC_004431.1 2887290 2887829 D Escherichia coli K-12 ortholog: b2506; Escherichia coli O157:H7 ortholog: z3770; hypothetical protein 2887290..2887829 Escherichia coli CFT073 1038696 NP_754908.1 CDS guaA NC_004431.1 2887923 2889500 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(2887923..2889500) Escherichia coli CFT073 1038697 NP_754909.1 CDS guaB NC_004431.1 2889569 2891104 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(2889569..2891104) Escherichia coli CFT073 1038699 NP_754910.1 CDS xseA NC_004431.1 2891197 2892573 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 2891197..2892573 Escherichia coli CFT073 1038700 NP_754911.1 CDS c3029 NC_004431.1 2892642 2900693 R Residues 9 to 2408 of 2683 are 42.82 pct identical to residues 13 to 2434 of 2435 from GenPept.129 : >gb|AAL21408.1| (AE008813) outer membrane protein [Salmonella typhimurium LT2]; RatA-like protein complement(2892642..2900693) Escherichia coli CFT073 1038701 NP_754912.1 CDS c3030 NC_004431.1 2900814 2901791 R Residues 1 to 325 of 325 are 46.24 pct identical to residues 1 to 319 of 319 from GenPept.129 : >gb|AAL21410.1| (AE008814) outer membrane protein [Salmonella typhimurium LT2]; SinI-like protein complement(2900814..2901791) Escherichia coli CFT073 1038702 NP_754913.1 CDS c3031 NC_004431.1 2901846 2904053 R Residues 11 to 735 of 735 are 72.77 pct identical to residues 1 to 730 of 730 from GenPept.129 : >gb|AAL21411.1| (AE008814) Similar to Escherichia coli intimin and Y. pestis invasin proteins [Salmonella typhimurium LT2]; SinH-like protein complement(2901846..2904053) Escherichia coli CFT073 1038703 NP_754914.1 CDS yfgJ NC_004431.1 2904232 2904447 R Escherichia coli K-12 ortholog: b2510; hypothetical protein complement(2904232..2904447) Escherichia coli CFT073 1038707 NP_754915.2 CDS engA NC_004431.1 2904510 2905982 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(2904510..2905982) Escherichia coli CFT073 1038709 NP_754916.1 CDS yfgL NC_004431.1 2906100 2907278 R with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL complement(2906100..2907278) Escherichia coli CFT073 1038710 NP_754917.1 CDS yfgM NC_004431.1 2907289 2907909 R Escherichia coli K-12 ortholog: b2513; Escherichia coli O157:H7 ortholog: z3776; hypothetical protein complement(2907289..2907909) Escherichia coli CFT073 1038711 NP_754918.1 CDS hisS NC_004431.1 2907927 2909201 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(2907927..2909201) Escherichia coli CFT073 1038712 NP_754919.1 CDS ispG NC_004431.1 2909312 2910430 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(2909312..2910430) Escherichia coli CFT073 1038713 NP_754920.1 CDS yfgA NC_004431.1 2910457 2911464 R Escherichia coli K-12 ortholog: b2516; Escherichia coli O157:H7 ortholog: z3779; cytoskeletal protein RodZ complement(2910457..2911464) Escherichia coli CFT073 1038716 NP_754921.1 CDS yfgB NC_004431.1 2911749 2912903 R 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N complement(2911749..2912903) Escherichia coli CFT073 1038717 NP_754922.1 CDS c3040 NC_004431.1 2913020 2913547 D hypothetical protein 2913020..2913547 Escherichia coli CFT073 1038718 NP_754923.1 CDS ndk NC_004431.1 2913053 2913484 R catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase complement(2913053..2913484) Escherichia coli CFT073 1038720 NP_754924.1 CDS pbpC NC_004431.1 2913633 2915945 R penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C complement(2913633..2915945) Escherichia coli CFT073 1038721 NP_754925.1 CDS yfhM NC_004431.1 2915946 2920907 R Escherichia coli K-12 ortholog: b2520; Escherichia coli O157:H7 ortholog: z3787; lipoprotein yfhM complement(2915946..2920907) Escherichia coli CFT073 1038722 NP_754926.2 CDS sseA NC_004431.1 2921114 2921959 D catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 2921114..2921959 Escherichia coli CFT073 1038726 NP_754927.1 CDS c3045 NC_004431.1 2921943 2922095 D hypothetical protein 2921943..2922095 Escherichia coli CFT073 1038728 NP_754928.1 CDS c3046 NC_004431.1 2922287 2922424 D hypothetical protein 2922287..2922424 Escherichia coli CFT073 1038730 NP_754929.2 CDS sseB NC_004431.1 2922456 2923232 R enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB complement(2922456..2923232) Escherichia coli CFT073 1038731 NP_754930.1 CDS pepB NC_004431.1 2923375 2924658 R catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase complement(2923375..2924658) Escherichia coli CFT073 1038732 NP_754931.1 CDS yfhJ NC_004431.1 2924717 2924917 R Escherichia coli K-12 ortholog: b2524; Escherichia coli O157:H7 ortholog: z3791; hypothetical protein complement(2924717..2924917) Escherichia coli CFT073 1038733 NP_754932.1 CDS fdx NC_004431.1 2924929 2925264 R Escherichia coli K-12 ortholog: b2525; Escherichia coli O157:H7 ortholog: z3792; (2Fe-2S) ferredoxin complement(2924929..2925264) Escherichia coli CFT073 1038734 NP_754933.2 CDS hscA NC_004431.1 2925266 2927116 R involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA complement(2925266..2927116) Escherichia coli CFT073 1038738 NP_754934.1 CDS hscB NC_004431.1 2927133 2927648 R J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB complement(2927133..2927648) Escherichia coli CFT073 1038740 NP_754935.2 CDS iscA NC_004431.1 2927744 2928067 R forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein complement(2927744..2928067) Escherichia coli CFT073 1038741 NP_754936.1 CDS c3054 NC_004431.1 2928003 2928485 D hypothetical protein 2928003..2928485 Escherichia coli CFT073 1038745 NP_754937.1 CDS c3055 NC_004431.1 2928084 2928470 R Escherichia coli K-12 ortholog: b2529; Escherichia coli O157:H7 ortholog: z3796; scaffold protein complement(2928084..2928470) Escherichia coli CFT073 1038750 NP_754938.1 CDS yfhO NC_004431.1 2928498 2929736 R catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase complement(2928498..2929736) Escherichia coli CFT073 1038751 NP_754939.1 CDS yfhP NC_004431.1 2929824 2930312 R regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR complement(2929824..2930312) Escherichia coli CFT073 1038755 NP_754940.1 CDS yfhQ NC_004431.1 2930583 2931323 R Escherichia coli K-12 ortholog: b2532; Escherichia coli O157:H7 ortholog: z3799; tRNA/rRNA methyltransferase YfhQ complement(2930583..2931323) Escherichia coli CFT073 1038756 NP_754941.1 CDS suhB NC_004431.1 2931442 2932245 D Escherichia coli K-12 ortholog: b2533; inositol monophosphatase 2931442..2932245 Escherichia coli CFT073 1038758 NP_754942.1 CDS yfhR NC_004431.1 2932363 2933244 D Escherichia coli K-12 ortholog: b2534; Escherichia coli O157:H7 ortholog: z3802; hypothetical protein 2932363..2933244 Escherichia coli CFT073 1038759 NP_754943.2 CDS csiE NC_004431.1 2933435 2934715 D Escherichia coli K-12 ortholog: b2535; Escherichia coli O157:H7 ortholog: z3804; stationary phase inducible protein CsiE 2933435..2934715 Escherichia coli CFT073 1038760 NP_754944.1 CDS hcaT NC_004431.1 2934707 2935846 R transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter complement(2934707..2935846) Escherichia coli CFT073 1038761 NP_754945.1 CDS c3063 NC_004431.1 2935880 2936023 R hypothetical protein complement(2935880..2936023) Escherichia coli CFT073 1038762 NP_754946.1 CDS c3064 NC_004431.1 2936066 2936218 D hypothetical protein 2936066..2936218 Escherichia coli CFT073 1038763 NP_754947.1 CDS yphA NC_004431.1 2936209 2936637 D Escherichia coli K-12 ortholog: b2543; Escherichia coli O157:H7 ortholog: z3815; hypothetical protein 2936209..2936637 Escherichia coli CFT073 1038764 NP_754948.1 CDS yphB NC_004431.1 2936797 2937669 R Escherichia coli K-12 ortholog: b2544; Escherichia coli O157:H7 ortholog: z3816; hypothetical protein complement(2936797..2937669) Escherichia coli CFT073 1038765 NP_754949.1 CDS yphC NC_004431.1 2937681 2938775 R Escherichia coli K-12 ortholog: b2545; Escherichia coli O157:H7 ortholog: z3817; hypothetical protein complement(2937681..2938775) Escherichia coli CFT073 1038767 NP_754950.1 CDS yphD NC_004431.1 2938808 2939806 R Escherichia coli K-12 ortholog: b2546; Escherichia coli O157:H7 ortholog: z3819; ABC transporter permease complement(2938808..2939806) Escherichia coli CFT073 1038768 NP_754951.1 CDS yphE NC_004431.1 2939831 2941342 R Escherichia coli K-12 ortholog: b2547; Escherichia coli O157:H7 ortholog: z3821; ABC transporter ATP-binding protein complement(2939831..2941342) Escherichia coli CFT073 1038769 NP_754952.1 CDS yphF NC_004431.1 2941365 2942348 R Escherichia coli K-12 ortholog: b2548; Escherichia coli O157:H7 ortholog: z3823; ABC transporter periplasmic-binding protein complement(2941365..2942348) Escherichia coli CFT073 1038771 NP_754953.1 CDS yphG NC_004431.1 2942445 2945819 R Escherichia coli K-12 ortholog: b2549; Escherichia coli O157:H7 ortholog: z3825; hypothetical protein complement(2942445..2945819) Escherichia coli CFT073 1038773 NP_754954.1 CDS yphH NC_004431.1 2945838 2947037 D Escherichia coli K-12 ortholog: b2550; Escherichia coli O157:H7 ortholog: z3826; hypothetical protein 2945838..2947037 Escherichia coli CFT073 1038774 NP_754955.1 CDS glyA NC_004431.1 2947101 2948360 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(2947101..2948360) Escherichia coli CFT073 1038775 NP_754956.1 CDS hmpA NC_004431.1 2948684 2949874 D flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 2948684..2949874 Escherichia coli CFT073 1038776 NP_754957.1 CDS glnB NC_004431.1 2949919 2950257 R indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 complement(2949919..2950257) Escherichia coli CFT073 1038777 NP_754958.1 CDS yfhA NC_004431.1 2950318 2951691 R ORF-2; Escherichia coli K-12 ortholog: b2554; Escherichia coli O157:H7 ortholog: z3830; hypothetical protein complement(2950318..2951691) Escherichia coli CFT073 1038779 NP_754959.1 CDS yfhG NC_004431.1 2951642 2952361 R Escherichia coli K-12 ortholog: b2555; Escherichia coli O157:H7 ortholog: z3831; hypothetical protein complement(2951642..2952361) Escherichia coli CFT073 1038780 NP_754960.1 CDS yfhK NC_004431.1 2952520 2954010 R Escherichia coli K-12 ortholog: b2556; Escherichia coli O157:H7 ortholog: z3833; sensor-like histidine kinase yfhK complement(2952520..2954010) Escherichia coli CFT073 1038781 NP_754961.1 CDS purL NC_004431.1 2954523 2958410 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase complement(2954523..2958410) Escherichia coli CFT073 1038782 NP_754962.1 CDS yfhD NC_004431.1 2958668 2960224 D YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 2958668..2960224 Escherichia coli CFT073 1038783 NP_754963.1 CDS yfhC NC_004431.1 2960221 2960757 R Escherichia coli K-12 ortholog: b2559; Escherichia coli O157:H7 ortholog: z3839; tRNA-specific adenosine deaminase complement(2960221..2960757) Escherichia coli CFT073 1038784 NP_754964.2 CDS yfhB NC_004431.1 2960782 2961417 R Escherichia coli K-12 ortholog: b2560; Escherichia coli O157:H7 ortholog: z3840; hypothetical protein complement(2960782..2961417) Escherichia coli CFT073 1038785 NP_754965.1 CDS c3084 NC_004431.1 2961378 2961515 R hypothetical protein complement(2961378..2961515) Escherichia coli CFT073 1038786 NP_754966.2 CDS yfhH NC_004431.1 2961626 2962474 D Escherichia coli K-12 ortholog: b2561; Escherichia coli O157:H7 ortholog: z3841; DNA-binding transcriptional regulator 2961626..2962474 Escherichia coli CFT073 1038788 NP_754967.1 CDS yfhL NC_004431.1 2962530 2962790 D Escherichia coli K-12 ortholog: b2562; Escherichia coli O157:H7 ortholog: z3842; ferredoxin-like protein yfhL 2962530..2962790 Escherichia coli CFT073 1038790 NP_754968.1 CDS acpS NC_004431.1 2963485 2963865 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(2963485..2963865) Escherichia coli CFT073 1038791 NP_754969.1 CDS pdxJ NC_004431.1 2963865 2964611 R involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase complement(2963865..2964611) Escherichia coli CFT073 1038793 NP_754970.1 CDS recO NC_004431.1 2964608 2965336 R involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO complement(2964608..2965336) Escherichia coli CFT073 1038794 NP_754971.1 CDS era NC_004431.1 2965348 2966253 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(2965348..2966253) Escherichia coli CFT073 1038795 NP_754972.1 CDS rnc NC_004431.1 2966250 2966930 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(2966250..2966930) Escherichia coli CFT073 1038796 NP_754973.1 CDS lepB NC_004431.1 2967202 2968176 R catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I complement(2967202..2968176) Escherichia coli CFT073 1038797 NP_754974.1 CDS lepA NC_004431.1 2968192 2969991 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(2968192..2969991) Escherichia coli CFT073 1038798 NP_754975.1 CDS rseC NC_004431.1 2970189 2970668 R involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC complement(2970189..2970668) Escherichia coli CFT073 1038799 NP_754976.1 CDS rseB NC_004431.1 2970665 2971621 R periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE complement(2970665..2971621) Escherichia coli CFT073 1038801 NP_754977.1 CDS rseA NC_004431.1 2971621 2972271 R Escherichia coli K-12 ortholog: b2572; Escherichia coli O157:H7 ortholog: z3854; anti-RNA polymerase sigma factor SigE complement(2971621..2972271) Escherichia coli CFT073 1038802 NP_754978.1 CDS rpoE NC_004431.1 2972304 2972912 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE complement(2972304..2972912) Escherichia coli CFT073 1038803 NP_754979.1 CDS nadB NC_004431.1 2973287 2974909 D catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 2973287..2974909 Escherichia coli CFT073 1038804 NP_754980.1 CDS yfiC NC_004431.1 2974894 2975751 R Escherichia coli K-12 ortholog: b2575; Escherichia coli O157:H7 ortholog: z3857; hypothetical protein complement(2974894..2975751) Escherichia coli CFT073 1038805 NP_754981.1 CDS srmB NC_004431.1 2975763 2977097 D facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 2975763..2977097 Escherichia coli CFT073 1038806 NP_754982.1 CDS yfiE NC_004431.1 2977130 2978056 R Escherichia coli K-12 ortholog: b2577; Escherichia coli O157:H7 ortholog: z3860; transcriptional regulator YfiE complement(2977130..2978056) Escherichia coli CFT073 1038808 NP_754983.1 CDS yfiK NC_004431.1 2978114 2978701 D Escherichia coli K-12 ortholog: b2578; Escherichia coli O157:H7 ortholog: z3861; neutral amino-acid efflux protein 2978114..2978701 Escherichia coli CFT073 1038810 NP_754984.2 CDS yfiD NC_004431.1 2978757 2979140 R stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA complement(2978757..2979140) Escherichia coli CFT073 1038814 NP_754985.1 CDS c3104 NC_004431.1 2978874 2979251 D hypothetical protein 2978874..2979251 Escherichia coli CFT073 1038815 NP_754986.1 CDS ung NC_004431.1 2979445 2980134 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 2979445..2980134 Escherichia coli CFT073 1038816 NP_754987.2 CDS yfiF NC_004431.1 2980183 2981220 R Escherichia coli K-12 ortholog: b2581; Escherichia coli O157:H7 ortholog: z3865; methyltransferase complement(2980183..2981220) Escherichia coli CFT073 1038820 NP_754988.1 CDS trxC NC_004431.1 2981427 2981846 D Escherichia coli K-12 ortholog: b2582; Escherichia coli O157:H7 ortholog: z3867; thioredoxin 2 2981427..2981846 Escherichia coli CFT073 1038821 NP_754989.1 CDS yfiP NC_004431.1 2981864 2982613 D Escherichia coli K-12 ortholog: b2583; Escherichia coli O157:H7 ortholog: z3868; hypothetical protein 2981864..2982613 Escherichia coli CFT073 1038822 NP_754990.1 CDS yfiQ NC_004431.1 2982645 2985305 D Escherichia coli K-12 ortholog: b2584; Escherichia coli O157:H7 ortholog: z3869; hypothetical protein 2982645..2985305 Escherichia coli CFT073 1038824 NP_754991.1 CDS pssA NC_004431.1 2985416 2986774 D catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 2985416..2986774 Escherichia coli CFT073 1038826 NP_754992.1 CDS yfiM NC_004431.1 2986799 2987143 D Escherichia coli K-12 ortholog: b2586; Escherichia coli O157:H7 ortholog: z3871; hypothetical protein 2986799..2987143 Escherichia coli CFT073 1038828 NP_754993.1 CDS kgtP NC_004431.1 2987140 2988531 R Escherichia coli K-12 ortholog: b2587; Escherichia coli O157:H7 ortholog: z3872; alpha-ketoglutarate transporter complement(2987140..2988531) Escherichia coli CFT073 1038829 NP_754994.1 CDS c3113 NC_004431.1 2994127 2994261 D hypothetical protein 2994127..2994261 Escherichia coli CFT073 1038838 NP_754995.1 CDS clpB NC_004431.1 2994301 2996886 R Heat shock protein F84.1; Escherichia coli K-12 ortholog: b2592; Escherichia coli O157:H7 ortholog: z3886; protein disaggregation chaperone complement(2994301..2996886) Escherichia coli CFT073 1038839 NP_754996.1 CDS yfiH NC_004431.1 2997004 2997735 R Escherichia coli K-12 ortholog: b2593; Escherichia coli O157:H7 ortholog: z3887; hypothetical protein complement(2997004..2997735) Escherichia coli CFT073 1038842 NP_754997.1 CDS rluD NC_004431.1 2997732 2998712 R responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D complement(2997732..2998712) Escherichia coli CFT073 1038843 NP_754998.1 CDS yfiO NC_004431.1 2998847 2999584 D with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 2998847..2999584 Escherichia coli CFT073 1038844 NP_754999.1 CDS c3118 NC_004431.1 2999773 3000309 R hypothetical protein complement(2999773..3000309) Escherichia coli CFT073 1038845 NP_755000.1 CDS yfiA NC_004431.1 2999854 3000195 D associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA 2999854..3000195 Escherichia coli CFT073 1038846 NP_755002.1 CDS pheA NC_004431.1 3000445 3001605 D catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 3000445..3001605 Escherichia coli CFT073 1038849 NP_755003.1 CDS tyrA NC_004431.1 3001648 3002769 R catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase complement(3001648..3002769) Escherichia coli CFT073 1038850 NP_755004.2 CDS aroF NC_004431.1 3002780 3003850 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(3002780..3003850) Escherichia coli CFT073 1038852 NP_755005.1 CDS yfiL NC_004431.1 3004042 3004425 D URF2; Escherichia coli K-12 ortholog: b2602; Escherichia coli O157:H7 ortholog: z3895; hypothetical protein 3004042..3004425 Escherichia coli CFT073 1038853 NP_755006.1 CDS yfiR NC_004431.1 3004572 3005090 D Escherichia coli K-12 ortholog: b2603; Escherichia coli O157:H7 ortholog: z3897; hypothetical protein 3004572..3005090 Escherichia coli CFT073 1038854 NP_755007.1 CDS yfiN NC_004431.1 3005080 3006306 D Escherichia coli K-12 ortholog: b2604; Escherichia coli O157:H7 ortholog: z3898; hypothetical protein 3005080..3006306 Escherichia coli CFT073 1038855 NP_755008.1 CDS yfiB NC_004431.1 3006322 3006804 D Escherichia coli K-12 ortholog: b2605; Escherichia coli O157:H7 ortholog: z3899; outer membrane lipoprotein 3006322..3006804 Escherichia coli CFT073 1038857 NP_755009.1 CDS rplS NC_004431.1 3006881 3007228 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(3006881..3007228) Escherichia coli CFT073 1038858 NP_755010.1 CDS trmD NC_004431.1 3007270 3008037 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(3007270..3008037) Escherichia coli CFT073 1038859 NP_755011.2 CDS rimM NC_004431.1 3008068 3008616 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(3008068..3008616) Escherichia coli CFT073 1038860 NP_755012.2 CDS rpsP NC_004431.1 3008635 3008883 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(3008635..3008883) Escherichia coli CFT073 1038861 NP_755013.1 CDS ffh NC_004431.1 3009020 3010381 R with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein complement(3009020..3010381) Escherichia coli CFT073 1038863 NP_755014.1 CDS ypjD NC_004431.1 3010473 3011339 D Escherichia coli K-12 ortholog: b2611; Escherichia coli O157:H7 ortholog: z3905; hypothetical protein 3010473..3011339 Escherichia coli CFT073 1038864 NP_755015.2 CDS c3133 NC_004431.1 3011450 3012646 D Fusion of Escherichia coli K-12 B2612 and B2613; Residues 1 to 420 of 420 are 99.28 pct identical to residues 9 to 428 of 428 from SwissProt.40 : >sp|P37908|YFJD_ECOLI HYPOTHETICAL 46.4 KDA PROTEIN IN FFH-GRPE INTERGENIC REGION; hypothetical protein 3011450..3012646 Escherichia coli CFT073 1038865 NP_755016.1 CDS c3134 NC_004431.1 3012668 3013420 D hypothetical protein 3012668..3013420 Escherichia coli CFT073 1038866 NP_755017.1 CDS grpE NC_004431.1 3012701 3013294 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(3012701..3013294) Escherichia coli CFT073 1038867 NP_755018.1 CDS c3136 NC_004431.1 3013291 3013542 R Residues 30 to 83 of 83 are 100.00 pct identical to residues 10 to 63 of 63 from SwissProt.40 : >sp|P37907|YFJC_ECOLI HYPOTHETICAL 7.0 KD PROTEIN IN GRPE-RECN INTERGENIC REGION; hypothetical protein complement(3013291..3013542) Escherichia coli CFT073 1038868 NP_755019.1 CDS ppnK NC_004431.1 3013417 3014295 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 3013417..3014295 Escherichia coli CFT073 1038869 NP_755020.1 CDS recN NC_004431.1 3014381 3016042 D Recombination protein N; Escherichia coli K-12 ortholog: b2616; Escherichia coli O157:H7 ortholog: z3909; recombination and repair protein 3014381..3016042 Escherichia coli CFT073 1038870 NP_755021.1 CDS c3139 NC_004431.1 3016191 3016532 D Residues 1 to 113 of 113 are 100.00 pct identical to residues 1 to 113 of 113 from SwissProt.40 : >sp|P23089|SMPA_ECOLI Small protein A precursor; hypothetical protein 3016191..3016532 Escherichia coli CFT073 1038872 NP_755022.2 CDS c3140 NC_004431.1 3016594 3016884 R Escherichia coli K-12 ortholog: b2618; Escherichia coli O157:H7 ortholog: z3911; hypothetical protein complement(3016594..3016884) Escherichia coli CFT073 1038873 NP_755023.1 CDS yfjG NC_004431.1 3016874 3017350 R Escherichia coli K-12 ortholog: b2619; Escherichia coli O157:H7 ortholog: z3912; hypothetical protein complement(3016874..3017350) Escherichia coli CFT073 1038874 NP_755024.1 CDS smpB NC_004431.1 3017482 3017964 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 3017482..3017964 Escherichia coli CFT073 1038875 NP_755025.1 CDS c3143 NC_004431.1 3018710 3019630 D hypothetical protein 3018710..3019630 Escherichia coli CFT073 1038876 NP_755026.1 CDS c3144 NC_004431.1 3019963 3020169 D Escherichia coli K-12 ortholog: b1061; Escherichia coli O157:H7 ortholog: z3916; DNA-damage-inducible protein I 3019963..3020169 Escherichia coli CFT073 1038877 NP_755027.1 CDS ydfK NC_004431.1 3020745 3021011 D Escherichia coli K-12 ortholog: b1544; hypothetical protein 3020745..3021011 Escherichia coli CFT073 1038878 NP_755028.1 CDS c3146 NC_004431.1 3021386 3021976 D Escherichia coli K-12 ortholog: b1374; Escherichia coli O157:H7 ortholog: z5885; DNA-invertase from lambdoid prophage Rac 3021386..3021976 Escherichia coli CFT073 1038880 NP_755029.1 CDS c3147 NC_004431.1 3022204 3022497 R hypothetical protein complement(3022204..3022497) Escherichia coli CFT073 1038881 NP_755030.1 CDS c3148 NC_004431.1 3022540 3023580 R Residues 110 to 233 of 346 are 31.25 pct identical to residues 486 to 611 of 669 from GenPept.129 : >gb|AAD03286.1| (AF063097) gpH [Enterobacteria phage P2]; hypothetical protein complement(3022540..3023580) Escherichia coli CFT073 1038882 NP_755031.1 CDS c3149 NC_004431.1 3023590 3023871 R hypothetical protein complement(3023590..3023871) Escherichia coli CFT073 1038884 NP_755032.1 CDS c3150 NC_004431.1 3023868 3026297 R Residues 118 to 438 of 809 are 30.28 pct identical to residues 291 to 638 of 973 from GenPept.129 : >gb|AAG56007.1|AE005333_4 (AE005333) membrane protein of prophage CP-933X [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(3023868..3026297) Escherichia coli CFT073 1038885 NP_755033.1 CDS c3151 NC_004431.1 3025462 3025902 D Residues 15 to 146 of 146 are 45.32 pct identical to residues 36 to 174 of 206 from SwissProt.40 : >sp|P03774|Y206_LAMBD HYPOTHETICAL PROTEIN ORF206; hypothetical protein 3025462..3025902 Escherichia coli CFT073 1038886 NP_755034.1 CDS c3152 NC_004431.1 3026388 3026897 R Residues 18 to 169 of 169 are 95.39 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein complement(3026388..3026897) Escherichia coli CFT073 1038888 NP_755035.1 CDS c3153 NC_004431.1 3027043 3027642 R Escherichia coli O157:H7 ortholog: z1917; outer membrane protein of prophage complement(3027043..3027642) Escherichia coli CFT073 1038889 NP_755036.1 CDS c3154 NC_004431.1 3027710 3031189 R Escherichia coli O157:H7 ortholog: z2145; tail component of prophage complement(3027710..3031189) Escherichia coli CFT073 1038891 NP_755037.1 CDS c3155 NC_004431.1 3031250 3031882 R Escherichia coli O157:H7 ortholog: z0979; tail component of prophage complement(3031250..3031882) Escherichia coli CFT073 1038892 NP_755038.1 CDS c3156 NC_004431.1 3031819 3032604 R Escherichia coli O157:H7 ortholog: z3081; tail fiber component K of prophage complement(3031819..3032604) Escherichia coli CFT073 1038893 NP_755039.1 CDS c3157 NC_004431.1 3032561 3033367 D hypothetical protein 3032561..3033367 Escherichia coli CFT073 1038895 NP_755040.1 CDS c3158 NC_004431.1 3032567 3033265 R Escherichia coli O157:H7 ortholog: z0977; tail component of prophage complement(3032567..3033265) Escherichia coli CFT073 1038898 NP_755041.1 CDS c3159 NC_004431.1 3033265 3033594 R Escherichia coli O157:H7 ortholog: z2353; tail component of prophage complement(3033265..3033594) Escherichia coli CFT073 1038899 NP_755042.1 CDS c3160 NC_004431.1 3033591 3036152 R Escherichia coli O157:H7 ortholog: z2140; tail component of prophage complement(3033591..3036152) Escherichia coli CFT073 1038900 NP_755043.1 CDS c3161 NC_004431.1 3036145 3036579 R Escherichia coli O157:H7 ortholog: z1896; tail component of prophage complement(3036145..3036579) Escherichia coli CFT073 1038902 NP_755044.1 CDS c3162 NC_004431.1 3036561 3036983 R Escherichia coli O157:H7 ortholog: z1895; tail component of prophage complement(3036561..3036983) Escherichia coli CFT073 1038904 NP_755045.1 CDS c3163 NC_004431.1 3036999 3037769 R Escherichia coli O157:H7 ortholog: z1894; tail component of prophage complement(3036999..3037769) Escherichia coli CFT073 1038906 NP_755046.1 CDS c3164 NC_004431.1 3037747 3038142 R Escherichia coli O157:H7 ortholog: z1893; tail component of prophage complement(3037747..3038142) Escherichia coli CFT073 1038907 NP_755047.1 CDS c3165 NC_004431.1 3038139 3038717 R Escherichia coli O157:H7 ortholog: z3089; tail fiber component Z of prophage complement(3038139..3038717) Escherichia coli CFT073 1038909 NP_755048.1 CDS c3166 NC_004431.1 3038729 3039082 R Escherichia coli O157:H7 ortholog: z1890; head-tail joining protein of prophage complement(3038729..3039082) Escherichia coli CFT073 1038910 NP_755049.1 CDS c3167 NC_004431.1 3039094 3039528 R Escherichia coli O157:H7 ortholog: z1889; DNA packaging protein of prophage complement(3039094..3039528) Escherichia coli CFT073 1038913 NP_755050.1 CDS c3168 NC_004431.1 3039531 3040556 R Escherichia coli O157:H7 ortholog: z1888; capsid protein of prophage complement(3039531..3040556) Escherichia coli CFT073 1038914 NP_755051.1 CDS c3169 NC_004431.1 3040611 3040949 R Escherichia coli O157:H7 ortholog: z1887; head-DNA stabilization protein of prophage complement(3040611..3040949) Escherichia coli CFT073 1038916 NP_755052.1 CDS c3170 NC_004431.1 3040953 3042386 R Escherichia coli O157:H7 ortholog: z1886; capsid protein of prophage complement(3040953..3042386) Escherichia coli CFT073 1038917 NP_755053.1 CDS c3171 NC_004431.1 3042253 3043854 R Escherichia coli O157:H7 ortholog: z1885; capsid structural protein of prophage complement(3042253..3043854) Escherichia coli CFT073 1038918 NP_755054.1 CDS c3172 NC_004431.1 3043851 3044057 R Escherichia coli O157:H7 ortholog: z1884; head-tail joining protein of prophage complement(3043851..3044057) Escherichia coli CFT073 1038920 NP_755055.1 CDS c3173 NC_004431.1 3044054 3045979 R Escherichia coli O157:H7 ortholog: z1883; DNA packaging protein of prophage complement(3044054..3045979) Escherichia coli CFT073 1038921 NP_755056.1 CDS nohB NC_004431.1 3045954 3046499 R Escherichia coli K-12 ortholog: b0560; Escherichia coli O157:H7 ortholog: z1882; prophage qsr' DNA packaging protein NU1-like protein complement(3045954..3046499) Escherichia coli CFT073 1038922 NP_755057.1 CDS c3175 NC_004431.1 3046059 3046598 D Residues 1 to 179 of 179 are 78.21 pct identical to residues 1 to 179 of 179 from GenPept.129 : >gb|AAB40756.1| (U82598) hypothetical protein [Escherichia coli]; hypothetical protein 3046059..3046598 Escherichia coli CFT073 1038923 NP_755058.3 CDS c3176 NC_004431.1 3047835 3048101 R Escherichia coli K-12 ortholog: b1550; GnsB protein complement(3047835..3048101) Escherichia coli CFT073 1038925 NP_755059.1 CDS cspI NC_004431.1 3048683 3048898 R CSP-I; Escherichia coli K-12 ortholog: b1552; Escherichia coli O157:H7 ortholog: z1406; cold shock-like protein cspI complement(3048683..3048898) Escherichia coli CFT073 1038926 NP_755060.1 CDS c3178 NC_004431.1 3048917 3049075 R hypothetical protein complement(3048917..3049075) Escherichia coli CFT073 1038927 NP_755061.1 CDS ydfP NC_004431.1 3049260 3049757 R Escherichia coli K-12 ortholog: b1553; hypothetical protein complement(3049260..3049757) Escherichia coli CFT073 1038928 NP_755062.1 CDS c3180 NC_004431.1 3049754 3050287 R Escherichia coli K-12 ortholog: b1554; Escherichia coli O157:H7 ortholog: z1796; lysozyme from lambdoid prophage Qin complement(3049754..3050287) Escherichia coli CFT073 1038929 NP_755063.1 CDS c3181 NC_004431.1 3050609 3051181 R Escherichia coli O157:H7 ortholog: z2070; hypothetical protein complement(3050609..3051181) Escherichia coli CFT073 1038930 NP_755064.1 CDS c3182 NC_004431.1 3051165 3051380 R Escherichia coli K-12 ortholog: b1556; Escherichia coli O157:H7 ortholog: z3340; lambdoid prophage Qin lysis protein S complement(3051165..3051380) Escherichia coli CFT073 1038932 NP_755065.1 CDS c3183 NC_004431.1 3051753 3051884 R hypothetical protein complement(3051753..3051884) Escherichia coli CFT073 1038933 NP_755066.1 CDS cspB NC_004431.1 3052133 3052348 R CSP-B; Escherichia coli K-12 ortholog: b1557; Escherichia coli O157:H7 ortholog: z4981; cold shock-like protein cspB complement(3052133..3052348) Escherichia coli CFT073 1038935 NP_755067.1 CDS cspF NC_004431.1 3052649 3052861 D CSP-F; Escherichia coli K-12 ortholog: b1558; Escherichia coli O157:H7 ortholog: z1405; cold shock-like protein cspF 3052649..3052861 Escherichia coli CFT073 1038936 NP_755068.1 CDS c3186 NC_004431.1 3053277 3054059 R Escherichia coli K-12 ortholog: b1559; Escherichia coli O157:H7 ortholog: z1345; lambdoid prophage Qin antitermination protein Q complement(3053277..3054059) Escherichia coli CFT073 1038937 NP_755069.1 CDS c3187 NC_004431.1 3054043 3055038 R Escherichia coli K-12 ortholog: b1560; Escherichia coli O157:H7 ortholog: z2100; hypothetical protein complement(3054043..3055038) Escherichia coli CFT073 1038938 NP_755070.1 CDS c3188 NC_004431.1 3055040 3055837 R Residues 1 to 265 of 265 are 88.84 pct identical to residues 1 to 269 of 269 from GenPept.129 : >gb|AAL89446.1| (U82619) unknown [Shigella flexneri bacteriophage V]; hypothetical protein complement(3055040..3055837) Escherichia coli CFT073 1038939 NP_755071.1 CDS c3189 NC_004431.1 3055857 3056246 R Residues 1 to 129 of 129 are 97.67 pct identical to residues 1 to 129 of 129 from GenPept.129 : >gb|AAL89445.1| (U82619) crossover junction endodeoxyribonuclease [Shigella flexneri bacteriophage V]; hypothetical protein complement(3055857..3056246) Escherichia coli CFT073 1038940 NP_755072.1 CDS c3190 NC_004431.1 3056243 3056602 R Residues 12 to 119 of 119 are 95.37 pct identical to residues 1 to 108 of 108 from GenPept.129 : >gb|AAL89444.1| (U82619) unknown [Shigella flexneri bacteriophage V]; hypothetical protein complement(3056243..3056602) Escherichia coli CFT073 1038941 NP_755073.1 CDS yfdN NC_004431.1 3056569 3057063 R Escherichia coli K-12 ortholog: b2357; hypothetical protein complement(3056569..3057063) Escherichia coli CFT073 1038942 NP_755074.1 CDS c3192 NC_004431.1 3057060 3058001 R Escherichia coli O157:H7 ortholog: z6070; hypothetical protein complement(3057060..3058001) Escherichia coli CFT073 1038943 NP_755077.1 CDS ymfL NC_004431.1 3058346 3058954 R Escherichia coli K-12 ortholog: b1147; hypothetical protein complement(3058346..3058954) Escherichia coli CFT073 1038948 NP_755078.1 CDS c3196 NC_004431.1 3058935 3059135 R Residues 1 to 65 of 66 are 53.84 pct identical to residues 1 to 65 of 75 from GenPept.129 : >dbj|BAB36188.1| (AP002559) cell division control protein [Escherichia coli O157:H7]; hypothetical protein complement(3058935..3059135) Escherichia coli CFT073 1038949 NP_755079.1 CDS c3197 NC_004431.1 3059233 3059859 D Escherichia coli O157:H7 ortholog: z3126; repressor protein of prophage 3059233..3059859 Escherichia coli CFT073 1038953 NP_755080.1 CDS c3198 NC_004431.1 3060075 3060587 R hypothetical protein complement(3060075..3060587) Escherichia coli CFT073 1038954 NP_755081.1 CDS c3199 NC_004431.1 3060560 3061243 R Residues 181 to 211 of 227 are 74.19 pct identical to residues 1 to 31 of 210 from GenPept.129 : >gb|AAG55872.1|AE005322_6 (AE005322) unknown protein encoded by prophage CP-933N [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(3060560..3061243) Escherichia coli CFT073 1038955 NP_755082.1 CDS c3200 NC_004431.1 3060731 3061417 D Residues 103 to 228 of 228 are 97.61 pct identical to residues 23 to 148 of 148 from GenPept.129 : >gb|AAC75418.1| (AE000324) orf, hypothetical protein [Escherichia coli K12]; hypothetical protein 3060731..3061417 Escherichia coli CFT073 1038956 NP_755083.1 CDS yfdQ NC_004431.1 3061483 3062307 D Escherichia coli K-12 ortholog: b2360; hypothetical protein 3061483..3062307 Escherichia coli CFT073 1038957 NP_755084.1 CDS yfdR NC_004431.1 3062408 3062959 D Escherichia coli K-12 ortholog: b2361; hypothetical protein 3062408..3062959 Escherichia coli CFT073 1038958 NP_755085.1 CDS c3203 NC_004431.1 3063044 3063934 D hypothetical protein 3063044..3063934 Escherichia coli CFT073 1038959 NP_755086.1 CDS c3204 NC_004431.1 3064143 3065315 D Residues 12 to 376 of 390 are 31.39 pct identical to residues 4 to 373 of 389 from GenPept.129 : >gb|AAG09988.1|AF251497_6 (AF251497) integrase [Cloning vector HKBS1]; hypothetical protein 3064143..3065315 Escherichia coli CFT073 1038960 NP_755087.1 CDS c3205 NC_004431.1 3065329 3065718 R Residues 3 to 126 of 129 are 32.35 pct identical to residues 1 to 135 of 142 from GenPept.129 : >emb|CAD05563.1| (AL627272) bacteriophage protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein complement(3065329..3065718) Escherichia coli CFT073 1038961 NP_755088.1 CDS c3206 NC_004431.1 3065702 3066517 R hypothetical protein complement(3065702..3066517) Escherichia coli CFT073 1038963 NP_755089.1 CDS ygaT NC_004431.1 3067657 3068634 D in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 3067657..3068634 Escherichia coli CFT073 1038966 NP_755090.1 CDS ygaF NC_004431.1 3068588 3069922 D catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 3068588..3069922 Escherichia coli CFT073 1038967 NP_755091.1 CDS gabD NC_004431.1 3069945 3071393 D catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I 3069945..3071393 Escherichia coli CFT073 1038968 NP_755092.1 CDS gabT NC_004431.1 3071401 3072687 D catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 3071401..3072687 Escherichia coli CFT073 1038970 NP_755093.3 CDS gabP NC_004431.1 3072861 3074324 D 4-amino butyrate transport carrier; Escherichia coli K-12 ortholog: b2663; Escherichia coli O157:H7 ortholog: z3961; gamma-aminobutyrate transporter 3072861..3074324 Escherichia coli CFT073 1038972 NP_755094.2 CDS ygaE NC_004431.1 3074345 3075007 D regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 3074345..3075007 Escherichia coli CFT073 1038973 NP_755095.1 CDS ygaU NC_004431.1 3075008 3075457 R Spot LM6; Escherichia coli K-12 ortholog: b2665; Escherichia coli O157:H7 ortholog: z3964; LysM domain/BON superfamily protein complement(3075008..3075457) Escherichia coli CFT073 1038974 NP_755096.1 CDS c3214 NC_004431.1 3075529 3075714 D hypothetical protein 3075529..3075714 Escherichia coli CFT073 1038975 NP_755097.1 CDS yqaE NC_004431.1 3075541 3075699 R Escherichia coli K-12 ortholog: b2666; Escherichia coli O157:H7 ortholog: z3965; hypothetical protein complement(3075541..3075699) Escherichia coli CFT073 1038976 NP_755098.1 CDS ygaV NC_004431.1 3075882 3076181 D Escherichia coli K-12 ortholog: b2667; Escherichia coli O157:H7 ortholog: z3966; transcriptional regulator YgaV 3075882..3076181 Escherichia coli CFT073 1038978 NP_755099.1 CDS ygaP NC_004431.1 3076191 3076715 D Escherichia coli K-12 ortholog: b2668; Escherichia coli O157:H7 ortholog: z3967; hypothetical protein 3076191..3076715 Escherichia coli CFT073 1038979 NP_755100.1 CDS stpA NC_004431.1 3076762 3077166 R H-NS homolog stpA; Escherichia coli K-12 ortholog: b2669; Escherichia coli O157:H7 ortholog: z3968; DNA binding protein, nucleoid-associated complement(3076762..3077166) Escherichia coli CFT073 1038981 NP_755101.1 CDS c3219 NC_004431.1 3077328 3077459 R hypothetical protein complement(3077328..3077459) Escherichia coli CFT073 1038982 NP_755102.1 CDS c3220 NC_004431.1 3077579 3077707 D hypothetical protein 3077579..3077707 Escherichia coli CFT073 1038983 NP_755103.1 CDS ygaW NC_004431.1 3077833 3078282 D Escherichia coli K-12 ortholog: b2670; Escherichia coli O157:H7 ortholog: z3970; hypothetical protein 3077833..3078282 Escherichia coli CFT073 1038984 NP_755104.1 CDS ygaC NC_004431.1 3078319 3078663 R Escherichia coli K-12 ortholog: b2671; Escherichia coli O157:H7 ortholog: z3971; hypothetical protein complement(3078319..3078663) Escherichia coli CFT073 1038985 NP_755105.1 CDS ygaM NC_004431.1 3078803 3079144 D Escherichia coli K-12 ortholog: b2672; Escherichia coli O157:H7 ortholog: z3972; hypothetical protein 3078803..3079144 Escherichia coli CFT073 1038986 NP_755106.1 CDS c3224 NC_004431.1 3079201 3080535 R Escherichia coli O157:H7 ortholog: z3973; hypothetical protein complement(3079201..3080535) Escherichia coli CFT073 1038987 NP_755107.1 CDS c3225 NC_004431.1 3080623 3081108 D Escherichia coli O157:H7 ortholog: z3974; hypothetical protein 3080623..3081108 Escherichia coli CFT073 1038989 NP_755108.1 CDS nrdH NC_004431.1 3081260 3081505 D Escherichia coli K-12 ortholog: b2673; Escherichia coli O157:H7 ortholog: z3975; glutaredoxin-like protein 3081260..3081505 Escherichia coli CFT073 1038990 NP_755109.1 CDS nrdI NC_004431.1 3081502 3081912 D in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 3081502..3081912 Escherichia coli CFT073 1038992 NP_755110.1 CDS nrdE NC_004431.1 3081885 3084029 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 3081885..3084029 Escherichia coli CFT073 1038993 NP_755111.1 CDS nrdF NC_004431.1 3084039 3084998 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 3084039..3084998 Escherichia coli CFT073 1038994 NP_755112.1 CDS proV NC_004431.1 3085355 3086557 D with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit 3085355..3086557 Escherichia coli CFT073 1038995 NP_755113.1 CDS proW NC_004431.1 3086550 3087614 D with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 3086550..3087614 Escherichia coli CFT073 1038997 NP_755114.2 CDS proX NC_004431.1 3087671 3088663 D with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 3087671..3088663 Escherichia coli CFT073 1038998 NP_755115.1 CDS c3233 NC_004431.1 3088716 3088862 D hypothetical protein 3088716..3088862 Escherichia coli CFT073 1038999 NP_755116.1 CDS c3234 NC_004431.1 3088855 3090039 D Escherichia coli K-12 ortholog: b2681; Escherichia coli O157:H7 ortholog: z3982; transport protein 3088855..3090039 Escherichia coli CFT073 1039000 NP_755117.1 CDS ygaZ NC_004431.1 3090164 3090901 D Escherichia coli K-12 ortholog: b2682; Escherichia coli O157:H7 ortholog: z3983; hypothetical protein 3090164..3090901 Escherichia coli CFT073 1039001 NP_755118.1 CDS ygaH NC_004431.1 3090891 3091226 D Escherichia coli K-12 ortholog: b2683; Escherichia coli O157:H7 ortholog: z3984; hypothetical protein 3090891..3091226 Escherichia coli CFT073 1039002 NP_755119.1 CDS emrR NC_004431.1 3091317 3091847 D DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 3091317..3091847 Escherichia coli CFT073 1039003 NP_755120.1 CDS emrA NC_004431.1 3091962 3093146 D Escherichia coli K-12 ortholog: b2685; Escherichia coli O157:H7 ortholog: z3986; multidrug resistance protein A 3091962..3093146 Escherichia coli CFT073 1039005 NP_755121.1 CDS emrB NC_004431.1 3093154 3094701 D Escherichia coli K-12 ortholog: b2686; Escherichia coli O157:H7 ortholog: z3987; multidrug resistance protein B 3093154..3094701 Escherichia coli CFT073 1039006 NP_755122.1 CDS c3240 NC_004431.1 3094959 3095315 D Residues 6 to 115 of 118 are 38.18 pct identical to residues 4 to 111 of 210 from GenPept.129 : >gb|AAF12618.1|AE001826_87 (AE001826) hypothetical protein [Deinococcus radiodurans]; hypothetical protein 3094959..3095315 Escherichia coli CFT073 1039009 NP_755123.1 CDS c3241 NC_004431.1 3095055 3095450 R hypothetical protein complement(3095055..3095450) Escherichia coli CFT073 1039011 NP_755124.1 CDS c3242 NC_004431.1 3095327 3095656 D hypothetical protein 3095327..3095656 Escherichia coli CFT073 1039012 NP_755125.1 CDS c3243 NC_004431.1 3095653 3096765 D Residues 16 to 359 of 370 are 37.50 pct identical to residues 19 to 360 of 363 from GenPept.129 : >gb|AAK78729.1|AE007591_2 (AE007591) PolyA polymerase related protein (HD hydrolase) and P-loop ATP-ase domain [Clostridium acetobutylicum]; hypothetical protein 3095653..3096765 Escherichia coli CFT073 1039013 NP_755126.1 CDS ygaG NC_004431.1 3096814 3097329 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(3096814..3097329) Escherichia coli CFT073 1039014 NP_755127.1 CDS gshA NC_004431.1 3097479 3099035 R involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase complement(3097479..3099035) Escherichia coli CFT073 1039015 NP_755128.1 CDS yqaA NC_004431.1 3099108 3099536 R Escherichia coli K-12 ortholog: b2689; Escherichia coli O157:H7 ortholog: z3990; hypothetical protein complement(3099108..3099536) Escherichia coli CFT073 1039017 NP_755129.1 CDS yqaB NC_004431.1 3099533 3100099 R YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase complement(3099533..3100099) Escherichia coli CFT073 1039018 NP_755130.1 CDS c3248 NC_004431.1 3100129 3100254 R hypothetical protein complement(3100129..3100254) Escherichia coli CFT073 1039019 NP_755131.1 CDS csrA NC_004431.1 3101427 3101612 R affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator complement(3101427..3101612) Escherichia coli CFT073 1039032 NP_755132.1 CDS c3251 NC_004431.1 3104383 3104553 D Residues 1 to 50 of 56 are 92.00 pct identical to residues 74 to 123 of 133 from GenPept.129 : >gb|AAG57802.1|AE005498_3 (AE005498) Z4000 gene product [Escherichia coli O157:H7 EDL933]; hypothetical protein 3104383..3104553 Escherichia coli CFT073 1039035 NP_755133.1 CDS recX NC_004431.1 3104607 3105107 R binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX complement(3104607..3105107) Escherichia coli CFT073 1039039 NP_755134.1 CDS recA NC_004431.1 3105176 3106237 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(3105176..3106237) Escherichia coli CFT073 1039040 NP_755135.1 CDS ygaD NC_004431.1 3106317 3106817 R Escherichia coli K-12 ortholog: b2700; Escherichia coli O157:H7 ortholog: z4003; competence damage-inducible protein A complement(3106317..3106817) Escherichia coli CFT073 1039043 NP_755136.1 CDS mltB NC_004431.1 3106959 3108149 R membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B complement(3106959..3108149) Escherichia coli CFT073 1039044 NP_755137.1 CDS srlA NC_004431.1 3108301 3108864 D EIIC2-GUT; Escherichia coli K-12 ortholog: b2702; Escherichia coli O157:H7 ortholog: z4005; PTS system, glucitol/sorbitol-specific IIC2 component 3108301..3108864 Escherichia coli CFT073 1039046 NP_755138.1 CDS srlE NC_004431.1 3108861 3109820 D EIIBC-GUT; Escherichia coli K-12 ortholog: b2703; Escherichia coli O157:H7 ortholog: z4009; PTS system, glucitol/sorbitol-specific IIBC component 3108861..3109820 Escherichia coli CFT073 1039048 NP_755139.1 CDS srlB NC_004431.1 3109831 3110202 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA 3109831..3110202 Escherichia coli CFT073 1039049 NP_755140.1 CDS srlD NC_004431.1 3110206 3110985 D catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 3110206..3110985 Escherichia coli CFT073 1039050 NP_755141.1 CDS gutM NC_004431.1 3111091 3111450 D regulator for glucitol utilization; DNA-binding transcriptional activator GutM 3111091..3111450 Escherichia coli CFT073 1039051 NP_755142.1 CDS srlR NC_004431.1 3111517 3112290 D regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 3111517..3112290 Escherichia coli CFT073 1039052 NP_755143.1 CDS gutQ NC_004431.1 3112283 3113248 D catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 3112283..3113248 Escherichia coli CFT073 1039055 NP_755144.2 CDS ygaA NC_004431.1 3113245 3114759 R Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcription regulator complement(3113245..3114759) Escherichia coli CFT073 1039057 NP_755145.1 CDS c3264 NC_004431.1 3114916 3115959 R Residues 288 to 347 of 347 are 94.99 pct identical to residues 1 to 60 of 60 from GenPept.129 : >gb|AAA92664.1| (U03846) ORF >60AA [Escherichia coli]; hypothetical protein complement(3114916..3115959) Escherichia coli CFT073 1039058 NP_755146.1 CDS ygbD NC_004431.1 3116383 3117516 D catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 3116383..3117516 Escherichia coli CFT073 1039063 NP_755147.1 CDS hypF NC_004431.1 3117740 3120064 R Escherichia coli K-12 ortholog: b2712; Escherichia coli O157:H7 ortholog: z4020; hydrogenase maturation protein hypF complement(3117740..3120064) Escherichia coli CFT073 1039064 NP_755148.1 CDS hydN NC_004431.1 3120145 3120687 R involved in electron transport from formate to hydrogen; electron transport protein HydN complement(3120145..3120687) Escherichia coli CFT073 1039066 NP_755149.1 CDS c3270 NC_004431.1 3120766 3120951 R hypothetical protein complement(3120766..3120951) Escherichia coli CFT073 1039067 NP_755150.1 CDS c3271 NC_004431.1 3121057 3121485 D hypothetical protein 3121057..3121485 Escherichia coli CFT073 1039068 NP_755151.1 CDS c3272 NC_004431.1 3121448 3121573 R hypothetical protein complement(3121448..3121573) Escherichia coli CFT073 1039070 NP_755152.1 CDS c3273 NC_004431.1 3121577 3121996 R Escherichia coli K-12 ortholog: b3082; Escherichia coli O157:H7 ortholog: z4435; hypothetical protein complement(3121577..3121996) Escherichia coli CFT073 1039071 NP_755153.1 CDS c3274 NC_004431.1 3121993 3122304 R Residues 1 to 103 of 103 are 58.25 pct identical to residues 1 to 103 of 103 from GenPept.129 : >gb|AAL22870.1| (AE008888) cytoplasmic protein [Salmonella typhimurium LT2]; hypothetical protein complement(3121993..3122304) Escherichia coli CFT073 1039073 NP_755154.1 CDS c3275 NC_004431.1 3122041 3122232 D hypothetical protein 3122041..3122232 Escherichia coli CFT073 1039074 NP_755155.1 CDS c3276 NC_004431.1 3122467 3123240 R Residues 12 to 257 of 257 are 72.17 pct identical to residues 22 to 269 of 269 from GenPept.129 : >gb|AAL21724.1| (AE008830) periplasmic or exported protein [Salmonella typhimurium LT2]; hypothetical protein complement(3122467..3123240) Escherichia coli CFT073 1039075 NP_755156.1 CDS hycI NC_004431.1 3123265 3123735 R involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease complement(3123265..3123735) Escherichia coli CFT073 1039079 NP_755157.1 CDS hycH NC_004431.1 3123728 3124138 R Escherichia coli K-12 ortholog: b2718; Escherichia coli O157:H7 ortholog: z4026; formate hydrogenlyase maturation protein hycH complement(3123728..3124138) Escherichia coli CFT073 1039080 NP_755158.1 CDS hycG NC_004431.1 3124135 3124902 R FHL subunit 7; Escherichia coli K-12 ortholog: b2719; Escherichia coli O157:H7 ortholog: z4027; formate hydrogenlyase subunit 7 complement(3124135..3124902) Escherichia coli CFT073 1039081 NP_755159.1 CDS hycF NC_004431.1 3124902 3125444 R electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit complement(3124902..3125444) Escherichia coli CFT073 1039083 NP_755160.1 CDS hycE NC_004431.1 3125454 3127163 R FHL subunit 5; Escherichia coli K-12 ortholog: b2721; Escherichia coli O157:H7 ortholog: z4029; formate hydrogenlyase subunit 5 complement(3125454..3127163) Escherichia coli CFT073 1039084 NP_755161.1 CDS hycD NC_004431.1 3127181 3128104 R FHL subunit 4; Escherichia coli K-12 ortholog: b2722; Escherichia coli O157:H7 ortholog: z4030; formate hydrogenlyase subunit 4 complement(3127181..3128104) Escherichia coli CFT073 1039085 NP_755162.1 CDS hycC NC_004431.1 3128107 3129933 R catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 complement(3128107..3129933) Escherichia coli CFT073 1039087 NP_755163.1 CDS hycB NC_004431.1 3129930 3130541 R FHL subunit 2; Escherichia coli K-12 ortholog: b2724; Escherichia coli O157:H7 ortholog: z4032; formate hydrogenlyase subunit 2 complement(3129930..3130541) Escherichia coli CFT073 1039088 NP_755164.1 CDS hycA NC_004431.1 3130666 3131127 R regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA complement(3130666..3131127) Escherichia coli CFT073 1039089 NP_755165.1 CDS hypA NC_004431.1 3131327 3131689 D plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 3131327..3131689 Escherichia coli CFT073 1039090 NP_755166.1 CDS hypB NC_004431.1 3131693 3132565 D GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 3131693..3132565 Escherichia coli CFT073 1039092 NP_755167.1 CDS hypC NC_004431.1 3132556 3132828 D HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 3132556..3132828 Escherichia coli CFT073 1039093 NP_755168.1 CDS hypD NC_004431.1 3132828 3133949 D Escherichia coli K-12 ortholog: b2729; Escherichia coli O157:H7 ortholog: z4038; hydrogenase isoenzyme formation protein hypD 3132828..3133949 Escherichia coli CFT073 1039094 NP_755169.1 CDS hypE NC_004431.1 3133946 3134956 D Escherichia coli K-12 ortholog: b2730; Escherichia coli O157:H7 ortholog: z4039; hydrogenase isoenzyme formation protein hypE 3133946..3134956 Escherichia coli CFT073 1039095 NP_755170.1 CDS fhlA NC_004431.1 3134994 3137108 D Escherichia coli K-12 ortholog: b2731; Escherichia coli O157:H7 ortholog: z4040; formate hydrogenlyase transcriptional activator 3134994..3137108 Escherichia coli CFT073 1039096 NP_755171.1 CDS c3292 NC_004431.1 3137114 3137581 D Residues 14 to 155 of 155 are 48.59 pct identical to residues 1 to 142 of 142 from GenPept.129 : >emb|CAA90038.1| (Z49882) potential molybdenum-pterin-binding-protein [Azotobacter vinelandii]; molybdenum-pterin-binding-protein 3137114..3137581 Escherichia coli CFT073 1039098 NP_755172.1 CDS ygbA NC_004431.1 3137620 3137964 R Escherichia coli K-12 ortholog: b2732; Escherichia coli O157:H7 ortholog: z4041; hypothetical protein complement(3137620..3137964) Escherichia coli CFT073 1039099 NP_755173.1 CDS mutS NC_004431.1 3138250 3140811 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 3138250..3140811 Escherichia coli CFT073 1039100 NP_755174.1 CDS pphB NC_004431.1 3140917 3141573 D Escherichia coli K-12 ortholog: b2734; Escherichia coli O157:H7 ortholog: z4044; serine/threonine-specific protein phosphatase 2 3140917..3141573 Escherichia coli CFT073 1039101 NP_755175.1 CDS ygbI NC_004431.1 3141624 3142421 R Escherichia coli K-12 ortholog: b2735; transcriptional regulator YgbI complement(3141624..3142421) Escherichia coli CFT073 1039105 NP_755176.1 CDS ygbJ NC_004431.1 3142587 3143495 D Escherichia coli K-12 ortholog: b2736; oxidoreductase ygbJ 3142587..3143495 Escherichia coli CFT073 1039107 NP_755177.1 CDS ygbK NC_004431.1 3143492 3144754 D Escherichia coli K-12 ortholog: b2737; hypothetical protein 3143492..3144754 Escherichia coli CFT073 1039109 NP_755178.1 CDS ygbL NC_004431.1 3144751 3145389 D Escherichia coli K-12 ortholog: b2738; aldolase 3144751..3145389 Escherichia coli CFT073 1039110 NP_755179.1 CDS ygbM NC_004431.1 3145394 3146170 D Escherichia coli K-12 ortholog: b2739; Escherichia coli O157:H7 ortholog: z0662; hypothetical protein 3145394..3146170 Escherichia coli CFT073 1039111 NP_755180.1 CDS ygbN NC_004431.1 3146259 3147623 D member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; inner membrane permease YgbN 3146259..3147623 Escherichia coli CFT073 1039112 NP_755181.1 CDS c3302 NC_004431.1 3147766 3148809 R Residues 1 to 347 of 347 are 100.00 pct identical to residues 1 to 347 of 347 from GenPept.129 : >gb|AAG27179.1|AF270497_4 (AF270497) unknown [Escherichia coli]; hypothetical protein complement(3147766..3148809) Escherichia coli CFT073 1039115 NP_755182.1 CDS c3303 NC_004431.1 3148828 3148974 D hypothetical protein 3148828..3148974 Escherichia coli CFT073 1039118 NP_755183.1 CDS c3304 NC_004431.1 3149034 3149585 D Residues 1 to 183 of 183 are 100.00 pct identical to residues 1 to 183 of 183 from GenPept.129 : >gb|AAG27178.1|AF270497_3 (AF270497) unknown [Escherichia coli]; hypothetical protein 3149034..3149585 Escherichia coli CFT073 1039119 NP_755184.1 CDS c3305 NC_004431.1 3149703 3150329 D hypothetical protein 3149703..3150329 Escherichia coli CFT073 1039120 NP_755185.1 CDS c3306 NC_004431.1 3149763 3150281 R Residues 1 to 172 of 172 are 100.00 pct identical to residues 159 to 330 of 330 from GenPept.129 : >gb|AAL01414.1|AF410777_1 (AF410777) RpoS [Escherichia coli]; hypothetical protein complement(3149763..3150281) Escherichia coli CFT073 1039121 NP_755186.1 CDS c3307 NC_004431.1 3150362 3150796 R Residues 13 to 144 of 144 are 99.24 pct identical to residues 1 to 132 of 330 from MG1655 : b2741; hypothetical protein complement(3150362..3150796) Escherichia coli CFT073 1039124 NP_755187.1 CDS nlpD NC_004431.1 3150823 3151962 R outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD complement(3150823..3151962) Escherichia coli CFT073 1039128 NP_755188.1 CDS c3309 NC_004431.1 3151820 3151987 D hypothetical protein 3151820..3151987 Escherichia coli CFT073 1039129 NP_755189.1 CDS pcm NC_004431.1 3152102 3152728 R catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase complement(3152102..3152728) Escherichia coli CFT073 1039130 NP_755190.1 CDS surE NC_004431.1 3152722 3153528 R catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE complement(3152722..3153528) Escherichia coli CFT073 1039131 NP_755191.1 CDS truD NC_004431.1 3153464 3154513 R catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D complement(3153464..3154513) Escherichia coli CFT073 1039133 NP_755192.1 CDS ispF NC_004431.1 3154510 3154989 R catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(3154510..3154989) Escherichia coli CFT073 1039136 NP_755193.1 CDS ispD NC_004431.1 3154989 3155699 R 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(3154989..3155699) Escherichia coli CFT073 1039137 NP_755194.1 CDS ftsB NC_004431.1 3155718 3156029 R forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB complement(3155718..3156029) Escherichia coli CFT073 1039142 NP_755195.1 CDS ygbE NC_004431.1 3156222 3156545 R Escherichia coli K-12 ortholog: b2749; Escherichia coli O157:H7 ortholog: z4057; hypothetical protein complement(3156222..3156545) Escherichia coli CFT073 1039143 NP_755196.1 CDS cysC NC_004431.1 3156597 3157202 R converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase complement(3156597..3157202) Escherichia coli CFT073 1039145 NP_755197.1 CDS cysN NC_004431.1 3157202 3158629 R may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 complement(3157202..3158629) Escherichia coli CFT073 1039146 NP_755198.1 CDS cysD NC_004431.1 3158631 3159539 R with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 complement(3158631..3159539) Escherichia coli CFT073 1039147 NP_755199.1 CDS iap NC_004431.1 3159791 3160828 D catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase 3159791..3160828 Escherichia coli CFT073 1039149 NP_755200.1 CDS cysH NC_004431.1 3161370 3162104 R catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase complement(3161370..3162104) Escherichia coli CFT073 1039150 NP_755201.1 CDS cysI NC_004431.1 3162178 3163890 R hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta complement(3162178..3163890) Escherichia coli CFT073 1039153 NP_755202.1 CDS cysJ NC_004431.1 3163890 3165689 R catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha complement(3163890..3165689) Escherichia coli CFT073 1039155 NP_755203.1 CDS ygcM NC_004431.1 3165921 3166370 D Escherichia coli K-12 ortholog: b2765; Escherichia coli O157:H7 ortholog: z4075; 6-pyruvoyl tetrahydrobiopterin synthase 3165921..3166370 Escherichia coli CFT073 1039156 NP_755204.1 CDS ygcN NC_004431.1 3166418 3167719 D Escherichia coli K-12 ortholog: b2766; Escherichia coli O157:H7 ortholog: z4076; electron transfer flavoprotein-quinone oxidoreductase ygcN 3166418..3167719 Escherichia coli CFT073 1039157 NP_755205.1 CDS ygcO NC_004431.1 3167674 3167970 D Escherichia coli K-12 ortholog: b2767; Escherichia coli O157:H7 ortholog: z4077; ferredoxin-like protein ygcO 3167674..3167970 Escherichia coli CFT073 1039158 NP_755206.1 CDS ygcQ NC_004431.1 3168711 3169604 R Escherichia coli K-12 ortholog: b2769; Escherichia coli O157:H7 ortholog: z4080; electron transfer flavoprotein subunit ygcQ complement(3168711..3169604) Escherichia coli CFT073 1039160 NP_755207.1 CDS ygcR NC_004431.1 3169568 3170350 R Escherichia coli K-12 ortholog: b2770; Escherichia coli O157:H7 ortholog: z4081; electron transfer flavoprotein subunit ygcR complement(3169568..3170350) Escherichia coli CFT073 1039161 NP_755208.1 CDS ygcS NC_004431.1 3170322 3171731 R Escherichia coli K-12 ortholog: b2771; Escherichia coli O157:H7 ortholog: z4083; metabolite transport protein complement(3170322..3171731) Escherichia coli CFT073 1039163 NP_755209.1 CDS c3331 NC_004431.1 3171753 3173207 R Residues 221 to 484 of 484 are 98.10 pct identical to residues 1 to 264 of 264 from MG1655 : b2772; hypothetical protein complement(3171753..3173207) Escherichia coli CFT073 1039164 NP_755210.1 CDS ygcW NC_004431.1 3173277 3174137 R Escherichia coli K-12 ortholog: b2774; Escherichia coli O157:H7 ortholog: z4085; oxidoreductase ygcW complement(3173277..3174137) Escherichia coli CFT073 1039165 NP_755211.1 CDS yqcE NC_004431.1 3174381 3175658 D Escherichia coli K-12 ortholog: b2775; Escherichia coli O157:H7 ortholog: z4086; hypothetical protein 3174381..3175658 Escherichia coli CFT073 1039168 NP_755212.1 CDS ygcE NC_004431.1 3175685 3177163 D Escherichia coli K-12 ortholog: b2776; Escherichia coli O157:H7 ortholog: z4087; sugar kinase ygcE 3175685..3177163 Escherichia coli CFT073 1039170 NP_755213.1 CDS ygcF NC_004431.1 3177637 3178308 R Escherichia coli K-12 ortholog: b2777; Escherichia coli O157:H7 ortholog: z4089; hypothetical protein complement(3177637..3178308) Escherichia coli CFT073 1039171 NP_755214.1 CDS c3336 NC_004431.1 3178342 3178467 D hypothetical protein 3178342..3178467 Escherichia coli CFT073 1039172 NP_755215.1 CDS c3337 NC_004431.1 3178481 3179083 D Escherichia coli O157:H7 ortholog: z4090; hypothetical protein 3178481..3179083 Escherichia coli CFT073 1039173 NP_755216.1 CDS c3338 NC_004431.1 3179067 3179990 D Escherichia coli O157:H7 ortholog: z4091; hypothetical protein 3179067..3179990 Escherichia coli CFT073 1039174 NP_755217.1 CDS c3339 NC_004431.1 3179594 3179884 R hypothetical protein complement(3179594..3179884) Escherichia coli CFT073 1039176 NP_755218.1 CDS c3340 NC_004431.1 3180005 3181159 D Escherichia coli O157:H7 ortholog: z4092; hypothetical protein 3180005..3181159 Escherichia coli CFT073 1039178 YP_004853817.1 CDS c3341 NC_004431.1 3180532 3180699 D hypothetical protein 3180532..3180699 Escherichia coli CFT073 1039179 NP_755220.1 CDS ygcG NC_004431.1 3181153 3182037 D Escherichia coli K-12 ortholog: b2778; Escherichia coli O157:H7 ortholog: z4093; hypothetical protein 3181153..3182037 Escherichia coli CFT073 1039180 NP_755221.1 CDS c3343 NC_004431.1 3182052 3183281 D hypothetical protein 3182052..3183281 Escherichia coli CFT073 1039182 NP_755222.1 CDS eno NC_004431.1 3182097 3183395 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(3182097..3183395) Escherichia coli CFT073 1039183 NP_755223.1 CDS pyrG NC_004431.1 3183483 3185120 R CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(3183483..3185120) Escherichia coli CFT073 1039184 NP_755224.1 CDS mazG NC_004431.1 3185348 3186139 R functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase complement(3185348..3186139) Escherichia coli CFT073 1039187 NP_755225.1 CDS relA NC_004431.1 3186235 3188469 R (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase complement(3186235..3188469) Escherichia coli CFT073 1039188 NP_755226.1 CDS rumA NC_004431.1 3188517 3189818 R in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase complement(3188517..3189818) Escherichia coli CFT073 1039189 NP_755227.1 CDS barA NC_004431.1 3189875 3192631 D part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 3189875..3192631 Escherichia coli CFT073 1039190 NP_755228.1 CDS ygcX NC_004431.1 3192862 3193989 R Escherichia coli K-12 ortholog: b2787; Escherichia coli O157:H7 ortholog: z4102; glucarate dehydratase complement(3192862..3193989) Escherichia coli CFT073 1039191 NP_755229.1 CDS ygcY NC_004431.1 3194225 3195565 R Escherichia coli K-12 ortholog: b2788; Escherichia coli O157:H7 ortholog: z4103; glucarate dehydratase-like protein complement(3194225..3195565) Escherichia coli CFT073 1039192 NP_755230.1 CDS c3353 NC_004431.1 3195567 3196919 R D-glucarate permease; Escherichia coli K-12 ortholog: b2789; Escherichia coli O157:H7 ortholog: z4105; glucarate transporter complement(3195567..3196919) Escherichia coli CFT073 1039193 NP_755231.1 CDS c3354 NC_004431.1 3197012 3197137 R hypothetical protein complement(3197012..3197137) Escherichia coli CFT073 1039194 NP_755232.1 CDS c3355 NC_004431.1 3197131 3197259 D hypothetical protein 3197131..3197259 Escherichia coli CFT073 1039195 NP_755233.1 CDS yqcA NC_004431.1 3197352 3197801 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(3197352..3197801) Escherichia coli CFT073 1039196 NP_755234.1 CDS yqcB NC_004431.1 3197819 3198601 R catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C complement(3197819..3198601) Escherichia coli CFT073 1039197 NP_755235.1 CDS yqcC NC_004431.1 3198601 3198930 R Escherichia coli K-12 ortholog: b2792; Escherichia coli O157:H7 ortholog: z4108; hypothetical protein complement(3198601..3198930) Escherichia coli CFT073 1039199 NP_755236.1 CDS syd NC_004431.1 3199552 3200097 R SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd complement(3199552..3200097) Escherichia coli CFT073 1039202 NP_755237.1 CDS queF NC_004431.1 3200165 3201013 D catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 3200165..3201013 Escherichia coli CFT073 1039203 NP_755238.1 CDS ygdH NC_004431.1 3201125 3202489 D Escherichia coli K-12 ortholog: b2795; Escherichia coli O157:H7 ortholog: z4112; hypothetical protein 3201125..3202489 Escherichia coli CFT073 1039204 NP_755239.1 CDS c3362 NC_004431.1 3202573 3202704 D hypothetical protein 3202573..3202704 Escherichia coli CFT073 1039205 NP_755240.1 CDS c3363 NC_004431.1 3203019 3204446 R hypothetical protein complement(3203019..3204446) Escherichia coli CFT073 1039206 NP_755241.1 CDS sdaC NC_004431.1 3203046 3204335 D Escherichia coli K-12 ortholog: b2796; Escherichia coli O157:H7 ortholog: z4113; Serine transporter 3203046..3204335 Escherichia coli CFT073 1039208 NP_755242.1 CDS sdaB NC_004431.1 3204393 3205760 D Escherichia coli K-12 ortholog: b2797; Escherichia coli O157:H7 ortholog: z4114; L-serine dehydratase 2 3204393..3205760 Escherichia coli CFT073 1039211 NP_755243.1 CDS xni NC_004431.1 3205782 3206627 D has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 3205782..3206627 Escherichia coli CFT073 1039213 NP_755244.1 CDS fucO NC_004431.1 3206732 3207883 R Escherichia coli K-12 ortholog: b2799; Escherichia coli O157:H7 ortholog: z4116; L-1,2-propanediol oxidoreductase complement(3206732..3207883) Escherichia coli CFT073 1039215 NP_755245.1 CDS fucA NC_004431.1 3207908 3208555 R catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase complement(3207908..3208555) Escherichia coli CFT073 1039216 NP_755246.1 CDS c3369 NC_004431.1 3208745 3208882 D hypothetical protein 3208745..3208882 Escherichia coli CFT073 1039219 NP_755247.1 CDS fucP NC_004431.1 3209102 3210418 D Escherichia coli K-12 ortholog: b2801; Escherichia coli O157:H7 ortholog: z4118; L-fucose transporter 3209102..3210418 Escherichia coli CFT073 1039220 NP_755248.1 CDS fucI NC_004431.1 3210451 3212226 D catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 3210451..3212226 Escherichia coli CFT073 1039222 NP_755249.1 CDS fucU NC_004431.1 3213754 3214176 D Escherichia coli K-12 ortholog: b2804; Escherichia coli O157:H7 ortholog: z4121; fucose operon fucU protein 3213754..3214176 Escherichia coli CFT073 1039226 NP_755250.1 CDS fucR NC_004431.1 3214225 3214965 D regulates expression of genes involved in L-fucose utilization; DNA-binding transcriptional activator FucR 3214225..3214965 Escherichia coli CFT073 1039228 NP_755251.1 CDS ygdE NC_004431.1 3215009 3216109 R Escherichia coli K-12 ortholog: b2806; Escherichia coli O157:H7 ortholog: z4123; RNA 2'-O-ribose methyltransferase complement(3215009..3216109) Escherichia coli CFT073 1039229 NP_755252.1 CDS ygdD NC_004431.1 3216102 3216404 R Escherichia coli K-12 ortholog: b2807; Escherichia coli O157:H7 ortholog: z4124; hypothetical protein complement(3216102..3216404) Escherichia coli CFT073 1039230 NP_755253.1 CDS gcvA NC_004431.1 3216516 3217433 R Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA complement(3216516..3217433) Escherichia coli CFT073 1039231 NP_755254.1 CDS c3379 NC_004431.1 3217751 3218044 D hypothetical protein 3217751..3218044 Escherichia coli CFT073 1039232 NP_755255.1 CDS ygdI NC_004431.1 3217784 3218014 R Escherichia coli K-12 ortholog: b2809; Escherichia coli O157:H7 ortholog: z4126; lipoprotein ygdI complement(3217784..3218014) Escherichia coli CFT073 1039233 NP_755256.1 CDS c3381 NC_004431.1 3218167 3219408 D Escherichia coli K-12 ortholog: b2810; Escherichia coli O157:H7 ortholog: z4127; cysteine sulfinate desulfinase 3218167..3219408 Escherichia coli CFT073 1039234 NP_755257.1 CDS ygdK NC_004431.1 3219408 3219851 D Escherichia coli K-12 ortholog: b2811; Escherichia coli O157:H7 ortholog: z4128; hypothetical protein 3219408..3219851 Escherichia coli CFT073 1039235 NP_755258.1 CDS ygdL NC_004431.1 3219902 3220708 R Escherichia coli K-12 ortholog: b2812; Escherichia coli O157:H7 ortholog: z4129; hypothetical protein complement(3219902..3220708) Escherichia coli CFT073 1039236 NP_755259.2 CDS mltA NC_004431.1 3220785 3221882 R membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A complement(3220785..3221882) Escherichia coli CFT073 1039237 NP_755260.1 CDS c3385 NC_004431.1 3223002 3223523 D Residues 9 to 171 of 173 are 73.61 pct identical to residues 3 to 165 of 166 from GenPept.129 : >emb|CAC90290.1| (AJ414148) conserved hypothetical protein [Yersinia pestis]; hypothetical protein 3223002..3223523 Escherichia coli CFT073 1039245 NP_755261.1 CDS c3386 NC_004431.1 3223576 3225120 D Escherichia coli O157:H7 ortholog: z0262; hypothetical protein 3223576..3225120 Escherichia coli CFT073 1039247 NP_755262.1 CDS c3387 NC_004431.1 3225140 3226477 D Residues 1 to 444 of 445 are 59.33 pct identical to residues 1 to 449 of 450 from GenPept.129 : >emb|CAC89820.1| (AJ414145) conserved hypothetical protein [Yersinia pestis]; hypothetical protein 3225140..3226477 Escherichia coli CFT073 1039248 NP_755263.1 CDS c3388 NC_004431.1 3226474 3227139 D Residues 8 to 218 of 221 are 51.38 pct identical to residues 13 to 226 of 228 from GenPept.129 : >emb|CAC90293.1| (AJ414148) membrane protein [Yersinia pestis]; hypothetical protein 3226474..3227139 Escherichia coli CFT073 1039249 NP_755264.1 CDS c3389 NC_004431.1 3227152 3228804 D Residues 6 to 550 of 550 are 41.51 pct identical to residues 6 to 562 of 578 from GenPept.129 : >emb|CAC90294.1| (AJ414148) exported protein [Yersinia pestis]; hypothetical protein 3227152..3228804 Escherichia coli CFT073 1039252 NP_755265.1 CDS c3390 NC_004431.1 3228841 3229443 R hypothetical protein complement(3228841..3229443) Escherichia coli CFT073 1039253 NP_755266.1 CDS c3391 NC_004431.1 3228862 3229353 D Residues 1 to 163 of 163 are 83.43 pct identical to residues 1 to 163 of 163 from GenPept.129 : >emb|CAC90295.1| (AJ414148) conserved hypothetical protein [Yersinia pestis]; secreted protein Hcp 3228862..3229353 Escherichia coli CFT073 1039254 NP_755267.1 CDS c3392 NC_004431.1 3229545 3232181 D Heat shock protein F84.1; Escherichia coli K-12 ortholog: b2592; Escherichia coli O157:H7 ortholog: z0254; ClpB protein 3229545..3232181 Escherichia coli CFT073 1039255 NP_755268.1 CDS c3393 NC_004431.1 3232181 3234655 D Residues 10 to 743 of 824 are 62.75 pct identical to residues 10 to 749 of 782 from GenPept.129 : >emb|CAC89815.1| (AJ414145) conserved hypothetical protein [Yersinia pestis]; hypothetical protein 3232181..3234655 Escherichia coli CFT073 1039256 NP_755269.1 CDS c3394 NC_004431.1 3234670 3235494 D hypothetical protein 3234670..3235494 Escherichia coli CFT073 1039257 NP_755270.1 CDS c3395 NC_004431.1 3235491 3237467 D Residues 30 to 634 of 658 are 31.40 pct identical to residues 41 to 639 of 746 from GenPept.129 : >emb|CAD14662.1| (AL646061) CONSERVED HYPOTHETICAL PROTEIN [Ralstonia solanacearum]; hypothetical protein 3235491..3237467 Escherichia coli CFT073 1039259 NP_755271.1 CDS c3396 NC_004431.1 3237477 3237749 D Residues 7 to 83 of 90 are 37.66 pct identical to residues 15 to 91 of 101 from GenPept.129 : >emb|CAC89712.1| (AJ414145) conserved hypothetical protein [Yersinia pestis]; hypothetical protein 3237477..3237749 Escherichia coli CFT073 1039260 NP_755272.1 CDS c3397 NC_004431.1 3237749 3239182 D hypothetical protein 3237749..3239182 Escherichia coli CFT073 1039263 NP_755273.1 CDS c3398 NC_004431.1 3239189 3242527 D Residues 78 to 1111 of 1112 are 50.43 pct identical to residues 97 to 1136 of 1140 from GenPept.129 : >emb|CAC90304.1| (AJ414148) membrane protein [Yersinia pestis]; hypothetical protein 3239189..3242527 Escherichia coli CFT073 1039264 NP_755274.1 CDS c3399 NC_004431.1 3242493 3244130 D Residues 10 to 539 of 545 are 60.82 pct identical to residues 1 to 532 of 533 from GenPept.129 : >emb|CAC90305.1| (AJ414148) hypothetical protein [Yersinia pestis]; hypothetical protein 3242493..3244130 Escherichia coli CFT073 1039266 NP_755275.1 CDS c3400 NC_004431.1 3244161 3246965 D Residues 2 to 539 of 934 are 73.33 pct identical to residues 1 to 539 of 587 from GenPept.129 : >emb|CAC90308.1| (AJ414148) conserved hypothetical protein [Yersinia pestis]; hypothetical protein 3244161..3246965 Escherichia coli CFT073 1039267 NP_755276.1 CDS c3401 NC_004431.1 3246946 3247482 D Residues 19 to 172 of 178 are 47.77 pct identical to residues 1 to 157 of 162 from GenPept.129 : >emb|CAC90310.1| (AJ414148) conserved hypothetical protein [Yersinia pestis]; hypothetical protein 3246946..3247482 Escherichia coli CFT073 1039268 NP_755277.1 CDS c3402 NC_004431.1 3247486 3247914 D Residues 2 to 138 of 142 are 59.12 pct identical to residues 5 to 141 of 150 from GenPept.129 : >emb|CAC90311.1| (AJ414148) conserved hypothetical protein [Yersinia pestis]; hypothetical protein 3247486..3247914 Escherichia coli CFT073 1039270 NP_755278.1 CDS c3403 NC_004431.1 3247914 3249290 D Residues 14 to 450 of 458 are 40.91 pct identical to residues 12 to 449 of 455 from GenPept.129 : >emb|CAC90312.1| (AJ414148) hypothetical protein [Yersinia pestis]; hypothetical protein 3247914..3249290 Escherichia coli CFT073 1039271 NP_755279.1 CDS c3404 NC_004431.1 3248464 3248616 R hypothetical protein complement(3248464..3248616) Escherichia coli CFT073 1039272 NP_755280.1 CDS c3405 NC_004431.1 3249590 3250546 R Residues 5 to 318 of 318 are 37.77 pct identical to residues 3 to 317 of 317 from GenPept.129 : >gb|AAK90773.1| (AE007909) AGR_pAT_578p [Agrobacterium tumefaciens str. C58 (Cereon)]; 2-hydroxyacid dehydrogenase complement(3249590..3250546) Escherichia coli CFT073 1039273 NP_755281.1 CDS c3406 NC_004431.1 3250609 3251205 R Residues 1 to 195 of 198 are 44.10 pct identical to residues 1 to 195 of 322 from SwissProt.40 : >sp|O67500|YF46_AQUAE Hypothetical protein AQ_1546; phosphosugar isomerase complement(3250609..3251205) Escherichia coli CFT073 1039274 NP_755282.1 CDS c3407 NC_004431.1 3251208 3252383 R Residues 1 to 336 of 391 are 99.70 pct identical to residues 1 to 336 of 336 from GenPept.129 : >gb|AAC61731.1| (AF081286) beta-cystathionase [Escherichia coli]; Beta-cystathionase complement(3251208..3252383) Escherichia coli CFT073 1039276 NP_755283.1 CDS c3408 NC_004431.1 3252383 3253963 R Maltose and glucose-permease IIABC component; Escherichia coli K-12 ortholog: b1621; Escherichia coli O157:H7 ortholog: z2626; PTS system, maltose and glucose-specific IIABC component complement(3252383..3253963) Escherichia coli CFT073 1039277 NP_755284.1 CDS c3409 NC_004431.1 3253995 3254876 R Residues 1 to 293 of 293 are 98.63 pct identical to residues 1 to 293 of 293 from GenPept.129 : >gb|AAC61733.1| (AF081286) sacpa operon antiterminator R1 [Escherichia coli]; antiterminator complement(3253995..3254876) Escherichia coli CFT073 1039278 NP_755285.1 CDS c3410 NC_004431.1 3254915 3255067 D hypothetical protein 3254915..3255067 Escherichia coli CFT073 1039279 NP_755286.1 CDS c3411 NC_004431.1 3255077 3256420 R Escherichia coli K-12 ortholog: b2817; Escherichia coli O157:H7 ortholog: z4134; N-acetylmuramoyl-L-alanine amidase complement(3255077..3256420) Escherichia coli CFT073 1039280 NP_755287.2 CDS argA NC_004431.1 3256562 3257893 D catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 3256562..3257893 Escherichia coli CFT073 1039282 NP_755288.1 CDS recD NC_004431.1 3257955 3259781 R helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha complement(3257955..3259781) Escherichia coli CFT073 1039285 NP_755289.1 CDS recB NC_004431.1 3259781 3263332 R helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta complement(3259781..3263332) Escherichia coli CFT073 1039286 NP_755290.1 CDS ptr NC_004431.1 3263316 3266204 R Escherichia coli K-12 ortholog: b2821; Escherichia coli O157:H7 ortholog: z4138; protease III complement(3263316..3266204) Escherichia coli CFT073 1039287 NP_755291.1 CDS recC NC_004431.1 3266380 3269748 R catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma complement(3266380..3269748) Escherichia coli CFT073 1039288 NP_755292.1 CDS ppdC NC_004431.1 3269761 3270084 R Escherichia coli K-12 ortholog: b2823; Escherichia coli O157:H7 ortholog: z4140; hypothetical protein complement(3269761..3270084) Escherichia coli CFT073 1039289 NP_755293.1 CDS ygdB NC_004431.1 3270069 3270476 R Escherichia coli K-12 ortholog: b2824; Escherichia coli O157:H7 ortholog: z4141; hypothetical protein complement(3270069..3270476) Escherichia coli CFT073 1039291 NP_755294.1 CDS ppdB NC_004431.1 3270473 3271060 R Escherichia coli K-12 ortholog: b2825; Escherichia coli O157:H7 ortholog: z4142; hypothetical protein complement(3270473..3271060) Escherichia coli CFT073 1039292 NP_755295.1 CDS ppdA NC_004431.1 3271027 3271497 R Escherichia coli K-12 ortholog: b2826; Escherichia coli O157:H7 ortholog: z4143; hypothetical protein complement(3271027..3271497) Escherichia coli CFT073 1039293 YP_004853818.1 CDS c3421 NC_004431.1 3271486 3271689 D hypothetical protein 3271486..3271689 Escherichia coli CFT073 1039294 NP_755297.1 CDS thyA NC_004431.1 3271682 3272476 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(3271682..3272476) Escherichia coli CFT073 1039295 NP_755298.1 CDS lgt NC_004431.1 3272483 3273358 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(3272483..3273358) Escherichia coli CFT073 1039296 NP_755299.1 CDS ptsP NC_004431.1 3273509 3275755 R member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain complement(3273509..3275755) Escherichia coli CFT073 1039297 NP_755300.1 CDS ygdP NC_004431.1 3275768 3276298 R hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase complement(3275768..3276298) Escherichia coli CFT073 1039298 NP_755301.1 CDS mutH NC_004431.1 3276983 3277672 D MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 3276983..3277672 Escherichia coli CFT073 1039299 NP_755302.1 CDS c3427 NC_004431.1 3277741 3278454 D Escherichia coli K-12 ortholog: b2832; Escherichia coli O157:H7 ortholog: z4150; hypothetical protein 3277741..3278454 Escherichia coli CFT073 1039301 NP_755303.1 CDS ygdR NC_004431.1 3278592 3278810 D Escherichia coli K-12 ortholog: b2833; Escherichia coli O157:H7 ortholog: z4151; lipoprotein ygdR 3278592..3278810 Escherichia coli CFT073 1039302 NP_755304.1 CDS tas NC_004431.1 3278918 3279958 D complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; aldo-keto reductase 3278918..3279958 Escherichia coli CFT073 1039303 NP_755305.1 CDS ygeD NC_004431.1 3279990 3281183 R Escherichia coli K-12 ortholog: b2835; Escherichia coli O157:H7 ortholog: z4153; lysophospholipid transporter LplT complement(3279990..3281183) Escherichia coli CFT073 1039304 NP_755306.1 CDS aas NC_004431.1 3281176 3283335 R Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase complement(3281176..3283335) Escherichia coli CFT073 1039306 NP_755307.1 CDS c3432 NC_004431.1 3283735 3284073 R Residues 1 to 112 of 112 are 96.42 pct identical to residues 41 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; transposase complement(3283735..3284073) Escherichia coli CFT073 1039308 NP_755308.1 CDS c3433 NC_004431.1 3284085 3284552 D hypothetical protein 3284085..3284552 Escherichia coli CFT073 1039310 NP_755309.1 CDS galR NC_004431.1 3284632 3285663 D controls transcription of galETKM; DNA-binding transcriptional regulator GalR 3284632..3285663 Escherichia coli CFT073 1039311 NP_755310.1 CDS lysA NC_004431.1 3285670 3286932 R catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase complement(3285670..3286932) Escherichia coli CFT073 1039312 NP_755311.1 CDS lysR NC_004431.1 3287054 3287989 D activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; LysR family transcriptional regulator 3287054..3287989 Escherichia coli CFT073 1039313 NP_755312.1 CDS ygeA NC_004431.1 3287976 3288668 R Escherichia coli K-12 ortholog: b2840; Escherichia coli O157:H7 ortholog: z4160; racemase complement(3287976..3288668) Escherichia coli CFT073 1039314 NP_755313.1 CDS araE NC_004431.1 3288797 3290344 R Arabinose transporter; Escherichia coli K-12 ortholog: b2841; Escherichia coli O157:H7 ortholog: z4161; arabinose-proton symporter complement(3288797..3290344) Escherichia coli CFT073 1039315 NP_755314.1 CDS kduD NC_004431.1 3290530 3291291 R catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase complement(3290530..3291291) Escherichia coli CFT073 1039316 NP_755315.1 CDS kduI NC_004431.1 3291321 3292157 R 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase complement(3291321..3292157) Escherichia coli CFT073 1039317 NP_755316.2 CDS yqeF NC_004431.1 3292444 3293625 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase complement(3292444..3293625) Escherichia coli CFT073 1039318 NP_755317.1 CDS yqeG NC_004431.1 3293880 3295109 D Escherichia coli K-12 ortholog: b2845; Escherichia coli O157:H7 ortholog: z4165; transport protein YqeG 3293880..3295109 Escherichia coli CFT073 1039319 NP_755318.1 CDS ygeR NC_004431.1 3295578 3296357 R Escherichia coli K-12 ortholog: b2865; Escherichia coli O157:H7 ortholog: z4203; lipoprotein ygeR complement(3295578..3296357) Escherichia coli CFT073 1039323 NP_755319.1 CDS c3444 NC_004431.1 3296747 3299044 D molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 3296747..3299044 Escherichia coli CFT073 1039325 NP_755320.1 CDS ygeT NC_004431.1 3299055 3299933 D FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 3299055..3299933 Escherichia coli CFT073 1039327 NP_755321.1 CDS c3446 NC_004431.1 3299930 3300409 D iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; xanthine dehydrogenase subunit XdhC 3299930..3300409 Escherichia coli CFT073 1039328 NP_755322.1 CDS ygeV NC_004431.1 3300449 3302227 R Escherichia coli K-12 ortholog: b2869; Escherichia coli O157:H7 ortholog: z4208; sigma-54-dependent transcriptional regulator ygeV complement(3300449..3302227) Escherichia coli CFT073 1039329 NP_755323.1 CDS ygeW NC_004431.1 3302703 3303893 D catalyzes the formation of L-citruline from L-ornithine and carbamoylphosphate; aspartate/ornithine carbamoyltransferase 3302703..3303893 Escherichia coli CFT073 1039330 NP_755324.1 CDS ygeX NC_004431.1 3303951 3305147 D catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 3303951..3305147 Escherichia coli CFT073 1039332 NP_755325.1 CDS ygeY NC_004431.1 3305205 3306416 D Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 3305205..3306416 Escherichia coli CFT073 1039333 NP_755326.2 CDS ygeZ NC_004431.1 3306470 3307855 D catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 3306470..3307855 Escherichia coli CFT073 1039334 NP_755327.1 CDS yqeA NC_004431.1 3307903 3308835 D catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 3307903..3308835 Escherichia coli CFT073 1039335 NP_755328.1 CDS yqeB NC_004431.1 3308876 3310501 R Escherichia coli K-12 ortholog: b2875; Escherichia coli O157:H7 ortholog: z4214; hypothetical protein complement(3308876..3310501) Escherichia coli CFT073 1039336 NP_755329.1 CDS yqeC NC_004431.1 3310549 3311319 R Escherichia coli K-12 ortholog: b2876; Escherichia coli O157:H7 ortholog: z4215; hypothetical protein complement(3310549..3311319) Escherichia coli CFT073 1039339 NP_755330.1 CDS ygfJ NC_004431.1 3311423 3312001 D Escherichia coli K-12 ortholog: b2877; Escherichia coli O157:H7 ortholog: z4216; hypothetical protein 3311423..3312001 Escherichia coli CFT073 1039340 NP_755331.1 CDS ygfK NC_004431.1 3312323 3315421 D with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; selenate reductase subunit YgfK 3312323..3315421 Escherichia coli CFT073 1039341 NP_755332.2 CDS c3457 NC_004431.1 3315424 3316752 D in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; chlorohydrolase/aminohydrolase 3315424..3316752 Escherichia coli CFT073 1039342 NP_755333.1 CDS ygfM NC_004431.1 3316803 3317582 D with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; selenate reductase subunit YgfM 3316803..3317582 Escherichia coli CFT073 1039345 NP_755334.1 CDS c3459 NC_004431.1 3317579 3320449 D with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; selenate reductase subunit YgfN 3317579..3320449 Escherichia coli CFT073 1039347 NP_755335.1 CDS ygfO NC_004431.1 3320557 3322014 D Escherichia coli K-12 ortholog: b2882; Escherichia coli O157:H7 ortholog: z4221; purine permease ygfO 3320557..3322014 Escherichia coli CFT073 1039348 NP_755336.1 CDS ygfP NC_004431.1 3321909 3323348 D Catalyzes the deamination of guanine; guanine deaminase 3321909..3323348 Escherichia coli CFT073 1039349 NP_755337.1 CDS c3462 NC_004431.1 3323384 3324751 D Escherichia coli K-12 ortholog: b4064; Escherichia coli O157:H7 ortholog: z4223; hypothetical protein 3323384..3324751 Escherichia coli CFT073 1039350 NP_755338.1 CDS ygfS NC_004431.1 3324787 3325278 R Escherichia coli K-12 ortholog: b2886; Escherichia coli O157:H7 ortholog: z4224; electron transport protein ygfS complement(3324787..3325278) Escherichia coli CFT073 1039351 NP_755339.1 CDS ygfT NC_004431.1 3325275 3327209 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit complement(3325275..3327209) Escherichia coli CFT073 1039353 NP_755340.1 CDS ygfU NC_004431.1 3327501 3329078 D Escherichia coli K-12 ortholog: b2888; Escherichia coli O157:H7 ortholog: z4226; purine permease ygfU 3327501..3329078 Escherichia coli CFT073 1039354 NP_755341.1 CDS c3466 NC_004431.1 3329062 3329205 D hypothetical protein 3329062..3329205 Escherichia coli CFT073 1039355 NP_755342.1 CDS c3467 NC_004431.1 3329328 3329876 D catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 3329328..3329876 Escherichia coli CFT073 1039356 NP_755343.1 CDS c3468 NC_004431.1 3329981 3330490 R Residues 18 to 169 of 169 are 94.07 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; hypothetical protein complement(3329981..3330490) Escherichia coli CFT073 1039359 NP_755344.1 CDS lysS NC_004431.1 3330630 3332147 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(3330630..3332147) Escherichia coli CFT073 1039360 NP_755345.1 CDS c3470 NC_004431.1 3330747 3332162 D hypothetical protein 3330747..3332162 Escherichia coli CFT073 1039361 NP_755346.1 CDS prfB NC_004431.1 3332157 3333255 R RF-2; recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 complement(join(3332157..3333179,3333181..3333255)) Escherichia coli CFT073 1039362 NP_755347.1 CDS recJ NC_004431.1 3333346 3335079 R 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ complement(3333346..3335079) Escherichia coli CFT073 1039363 NP_755348.1 CDS dsbC NC_004431.1 3335085 3335795 R DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC complement(3335085..3335795) Escherichia coli CFT073 1039364 NP_755349.1 CDS xerD NC_004431.1 3335820 3336716 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD complement(3335820..3336716) Escherichia coli CFT073 1039365 NP_755350.1 CDS fldB NC_004431.1 3336828 3337349 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 3336828..3337349 Escherichia coli CFT073 1039367 NP_755351.1 CDS ygfX NC_004431.1 3337389 3337796 R Escherichia coli K-12 ortholog: b2896; Escherichia coli O157:H7 ortholog: z4234; hypothetical protein complement(3337389..3337796) Escherichia coli CFT073 1039368 NP_755352.1 CDS ygfY NC_004431.1 3337777 3338043 R Escherichia coli K-12 ortholog: b2897; Escherichia coli O157:H7 ortholog: z4235; hypothetical protein complement(3337777..3338043) Escherichia coli CFT073 1039369 NP_755353.1 CDS c3478 NC_004431.1 3338018 3338209 D hypothetical protein 3338018..3338209 Escherichia coli CFT073 1039371 NP_755354.1 CDS ygfZ NC_004431.1 3338286 3339266 D physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; global regulator 3338286..3339266 Escherichia coli CFT073 1039372 NP_755355.1 CDS yqfA NC_004431.1 3339343 3340002 R Escherichia coli K-12 ortholog: b2899; Escherichia coli O157:H7 ortholog: z4237; hypothetical protein complement(3339343..3340002) Escherichia coli CFT073 1039374 NP_755356.1 CDS yqfB NC_004431.1 3340166 3340477 R Escherichia coli K-12 ortholog: b2900; Escherichia coli O157:H7 ortholog: z4238; hypothetical protein complement(3340166..3340477) Escherichia coli CFT073 1039375 NP_755357.1 CDS bglA NC_004431.1 3340498 3341955 D Escherichia coli K-12 ortholog: b2901; Escherichia coli O157:H7 ortholog: z4239; 6-phospho-beta-glucosidase 3340498..3341955 Escherichia coli CFT073 1039376 NP_755358.1 CDS gcvP NC_004431.1 3342121 3344994 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase complement(3342121..3344994) Escherichia coli CFT073 1039377 NP_755359.1 CDS gcvH NC_004431.1 3345112 3345504 R part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H complement(3345112..3345504) Escherichia coli CFT073 1039378 NP_755360.1 CDS gcvT NC_004431.1 3345525 3346619 R catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T complement(3345525..3346619) Escherichia coli CFT073 1039380 NP_755361.1 CDS c3486 NC_004431.1 3346627 3346782 R hypothetical protein complement(3346627..3346782) Escherichia coli CFT073 1039381 NP_755362.1 CDS c3487 NC_004431.1 3346795 3346944 R hypothetical protein complement(3346795..3346944) Escherichia coli CFT073 1039382 NP_755363.1 CDS visC NC_004431.1 3347067 3348269 R Escherichia coli K-12 ortholog: b2906; Escherichia coli O157:H7 ortholog: z4243; hypothetical protein complement(3347067..3348269) Escherichia coli CFT073 1039383 NP_755364.1 CDS ubiH NC_004431.1 3348292 3349470 R Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase complement(3348292..3349470) Escherichia coli CFT073 1039384 NP_755365.1 CDS pepP NC_004431.1 3349467 3350792 R exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II complement(3349467..3350792) Escherichia coli CFT073 1039385 NP_755366.2 CDS ygfB NC_004431.1 3350818 3351396 R the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein complement(3350818..3351396) Escherichia coli CFT073 1039386 NP_755367.1 CDS ygfE NC_004431.1 3351564 3351893 D Escherichia coli K-12 ortholog: b2910; Escherichia coli O157:H7 ortholog: z4247; Z-ring-associated protein 3351564..3351893 Escherichia coli CFT073 1039387 NP_755368.2 CDS ygfA NC_004431.1 3352193 3352741 D ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; ligase 3352193..3352741 Escherichia coli CFT073 1039389 NP_755369.1 CDS serA NC_004431.1 3353131 3354363 R catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase complement(3353131..3354363) Escherichia coli CFT073 1039390 NP_755370.1 CDS rpiA NC_004431.1 3354619 3355350 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(3354619..3355350) Escherichia coli CFT073 1039391 NP_755371.1 CDS yqfE NC_004431.1 3355334 3355612 R Escherichia coli K-12 ortholog: b2915; hypothetical protein complement(3355334..3355612) Escherichia coli CFT073 1039392 NP_755372.2 CDS iciA NC_004431.1 3355705 3356598 D specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 3355705..3356598 Escherichia coli CFT073 1039393 NP_755373.1 CDS c3498 NC_004431.1 3356801 3357856 D Residues 1 to 309 of 351 are 86.88 pct identical to residues 1 to 343 of 714 from MG1655 : b2917; hypothetical protein 3356801..3357856 Escherichia coli CFT073 1039394 NP_755374.1 CDS ygfI NC_004431.1 3357853 3358749 R Escherichia coli K-12 ortholog: b2921; Escherichia coli O157:H7 ortholog: z4258; transcriptional regulator YgfI complement(3357853..3358749) Escherichia coli CFT073 1039395 NP_755375.1 CDS yggE NC_004431.1 3358907 3359647 R Escherichia coli K-12 ortholog: b2922; Escherichia coli O157:H7 ortholog: z4259; hypothetical protein complement(3358907..3359647) Escherichia coli CFT073 1039396 NP_755376.1 CDS yggA NC_004431.1 3359740 3360375 R Involved in the export of arginine; arginine exporter protein complement(3359740..3360375) Escherichia coli CFT073 1039397 NP_755377.1 CDS yggB NC_004431.1 3360514 3361374 R participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS complement(3360514..3361374) Escherichia coli CFT073 1039400 NP_755378.2 CDS fba NC_004431.1 3361565 3362644 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase complement(3361565..3362644) Escherichia coli CFT073 1039401 NP_755379.1 CDS pgk NC_004431.1 3362858 3364084 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(3362858..3364084) Escherichia coli CFT073 1039404 NP_755380.2 CDS epd NC_004431.1 3364071 3365090 R NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase complement(3364071..3365090) Escherichia coli CFT073 1039405 NP_755381.1 CDS c3506 NC_004431.1 3365462 3365890 D Escherichia coli O157:H7 ortholog: z4267; hypothetical protein 3365462..3365890 Escherichia coli CFT073 1039406 NP_755382.1 CDS c3507 NC_004431.1 3365917 3366495 D Escherichia coli O157:H7 ortholog: z4268; hypothetical protein 3365917..3366495 Escherichia coli CFT073 1039407 NP_755383.1 CDS c3508 NC_004431.1 3366496 3367203 D Escherichia coli O157:H7 ortholog: z4269; hypothetical protein 3366496..3367203 Escherichia coli CFT073 1039408 NP_755384.1 CDS c3509 NC_004431.1 3367332 3367868 D Escherichia coli O157:H7 ortholog: z4270; ABC transporter ATP-binding protein 3367332..3367868 Escherichia coli CFT073 1039409 NP_755385.1 CDS c3510 NC_004431.1 3367829 3368539 D Escherichia coli O157:H7 ortholog: z4271; ABC transporter ATP-binding protein 3367829..3368539 Escherichia coli CFT073 1039410 NP_755386.1 CDS frcK NC_004431.1 3368511 3369224 R Escherichia coli K-12 ortholog: b2928; Escherichia coli O157:H7 ortholog: z4273; fructose transport system kinase complement(3368511..3369224) Escherichia coli CFT073 1039411 NP_755387.1 CDS yggD NC_004431.1 3369221 3369730 R Escherichia coli K-12 ortholog: b2929; Escherichia coli O157:H7 ortholog: z4274; DNA-binding transcriptional regulator complement(3369221..3369730) Escherichia coli CFT073 1039417 NP_755388.1 CDS c3513 NC_004431.1 3369879 3370067 R Residues 1 to 58 of 62 are 100.00 pct identical to residues 1 to 58 of 321 from MG1655 : b2930; hypothetical protein complement(3369879..3370067) Escherichia coli CFT073 1039419 NP_755389.1 CDS c3514 NC_004431.1 3370064 3371341 R Escherichia coli K-12 ortholog: b2931; Escherichia coli O157:H7 ortholog: z4276; oxidoreductase complement(3370064..3371341) Escherichia coli CFT073 1039420 NP_755390.1 CDS cmtA NC_004431.1 3371356 3372744 R EIIBC-(C)MTL; Escherichia coli K-12 ortholog: b2933; Escherichia coli O157:H7 ortholog: z4277; PTS system, mannitol (Cryptic)-specific IIBC component complement(3371356..3372744) Escherichia coli CFT073 1039421 NP_755391.1 CDS cmtB NC_004431.1 3372772 3373215 R TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; mannitol phosphotransferase subunit EIIA complement(3372772..3373215) Escherichia coli CFT073 1039424 NP_755392.1 CDS c3517 NC_004431.1 3373532 3374266 D Residues 38 to 224 of 244 are 48.93 pct identical to residues 18 to 205 of 308 from GenPept.129 : >emb|CAC90171.1| (AJ414147) SPFH domain protein [Yersinia pestis]; hypothetical protein 3373532..3374266 Escherichia coli CFT073 1039426 YP_004853819.1 CDS c3518 NC_004431.1 3374240 3374698 R hypothetical protein complement(3374240..3374698) Escherichia coli CFT073 1039427 YP_004853820.1 CDS c3519 NC_004431.1 3374337 3374705 R hypothetical protein complement(3374337..3374705) Escherichia coli CFT073 1039429 NP_755395.2 CDS tktA NC_004431.1 3374714 3376705 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(3374714..3376705) Escherichia coli CFT073 1039430 NP_755396.1 CDS yggG NC_004431.1 3376764 3377741 D Escherichia coli K-12 ortholog: b2936; Escherichia coli O157:H7 ortholog: z4280; metalloprotease yggG 3376764..3377741 Escherichia coli CFT073 1039431 NP_755397.1 CDS speB NC_004431.1 3377945 3378865 R catalyzes the formation of putrescine from agmatine; agmatinase complement(3377945..3378865) Escherichia coli CFT073 1039433 NP_755398.1 CDS c3523 NC_004431.1 3379001 3379732 R Escherichia coli O157:H7 ortholog: z4282; hypothetical protein complement(3379001..3379732) Escherichia coli CFT073 1039435 NP_755399.1 CDS speA NC_004431.1 3379878 3381866 R catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase complement(3379878..3381866) Escherichia coli CFT073 1039437 NP_755400.1 CDS yqgB NC_004431.1 3381863 3382009 R Escherichia coli K-12 ortholog: b2939; Escherichia coli O157:H7 ortholog: z4284; hypothetical protein complement(3381863..3382009) Escherichia coli CFT073 1039438 NP_755401.1 CDS c3526 NC_004431.1 3382329 3382454 D hypothetical protein 3382329..3382454 Escherichia coli CFT073 1039439 NP_755402.1 CDS yqgD NC_004431.1 3382342 3382608 R Escherichia coli K-12 ortholog: b2941; Escherichia coli O157:H7 ortholog: z4286; hypothetical protein complement(3382342..3382608) Escherichia coli CFT073 1039440 NP_755403.2 CDS metK NC_004431.1 3382649 3383803 D methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 3382649..3383803 Escherichia coli CFT073 1039441 NP_755404.1 CDS galP NC_004431.1 3384227 3385633 D Galactose transporter; Escherichia coli K-12 ortholog: b2943; Escherichia coli O157:H7 ortholog: z4288; galactose-proton symporter 3384227..3385633 Escherichia coli CFT073 1039442 NP_755405.1 CDS sprT NC_004431.1 3385656 3386207 D Escherichia coli K-12 ortholog: b2944; Escherichia coli O157:H7 ortholog: z4289; hypothetical protein 3385656..3386207 Escherichia coli CFT073 1039443 NP_755406.1 CDS endA NC_004431.1 3386299 3387009 D Escherichia coli K-12 ortholog: b2945; Escherichia coli O157:H7 ortholog: z4290; endonuclease I 3386299..3387009 Escherichia coli CFT073 1039444 NP_755407.2 CDS yggJ NC_004431.1 3387089 3387820 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 3387089..3387820 Escherichia coli CFT073 1039445 NP_755408.1 CDS gshB NC_004431.1 3387833 3388783 D catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 3387833..3388783 Escherichia coli CFT073 1039448 NP_755409.2 CDS yqgE NC_004431.1 3388892 3389455 D Escherichia coli K-12 ortholog: b2948; Escherichia coli O157:H7 ortholog: z4293; hypothetical protein 3388892..3389455 Escherichia coli CFT073 1039449 NP_755410.1 CDS yqgF NC_004431.1 3389455 3389871 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 3389455..3389871 Escherichia coli CFT073 1039450 NP_755411.1 CDS yggR NC_004431.1 3390045 3391100 R Escherichia coli K-12 ortholog: b2950; Escherichia coli O157:H7 ortholog: z4295; hypothetical protein complement(3390045..3391100) Escherichia coli CFT073 1039451 NP_755412.1 CDS yggS NC_004431.1 3391043 3391747 D Escherichia coli K-12 ortholog: b2951; Escherichia coli O157:H7 ortholog: z4296; hypothetical protein 3391043..3391747 Escherichia coli CFT073 1039453 NP_755413.1 CDS yggT NC_004431.1 3391765 3392331 D Escherichia coli K-12 ortholog: b2952; Escherichia coli O157:H7 ortholog: z4297; hypothetical protein 3391765..3392331 Escherichia coli CFT073 1039454 NP_755414.2 CDS yggU NC_004431.1 3392328 3392618 D Escherichia coli K-12 ortholog: b2953; Escherichia coli O157:H7 ortholog: z4298; hypothetical protein 3392328..3392618 Escherichia coli CFT073 1039455 NP_755415.1 CDS yggV NC_004431.1 3392626 3393219 D HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 3392626..3393219 Escherichia coli CFT073 1039457 NP_755416.1 CDS yggW NC_004431.1 3393212 3394348 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3393212..3394348 Escherichia coli CFT073 1039458 NP_755417.1 CDS yggM NC_004431.1 3394417 3395424 R Escherichia coli K-12 ortholog: b2956; Escherichia coli O157:H7 ortholog: z4301; hypothetical protein complement(3394417..3395424) Escherichia coli CFT073 1039459 NP_755418.1 CDS ansB NC_004431.1 3395541 3396587 R catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II complement(3395541..3396587) Escherichia coli CFT073 1039460 NP_755419.1 CDS yggN NC_004431.1 3396763 3397482 R Escherichia coli K-12 ortholog: b2958; Escherichia coli O157:H7 ortholog: z4303; hypothetical protein complement(3396763..3397482) Escherichia coli CFT073 1039461 NP_755420.1 CDS c3545 NC_004431.1 3397503 3397643 R hypothetical protein complement(3397503..3397643) Escherichia coli CFT073 1039462 NP_755421.2 CDS yggL NC_004431.1 3397666 3397992 R Escherichia coli K-12 ortholog: b2959; Escherichia coli O157:H7 ortholog: z4304; hypothetical protein complement(3397666..3397992) Escherichia coli CFT073 1039463 NP_755422.1 CDS trmB NC_004431.1 3397992 3398711 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(3397992..3398711) Escherichia coli CFT073 1039465 NP_755423.1 CDS mutY NC_004431.1 3398842 3399924 D Escherichia coli K-12 ortholog: b2961; Escherichia coli O157:H7 ortholog: z4306; adenine DNA glycosylase 3398842..3399924 Escherichia coli CFT073 1039467 NP_755424.1 CDS c3549 NC_004431.1 3399901 3400194 R hypothetical protein complement(3399901..3400194) Escherichia coli CFT073 1039468 NP_755425.1 CDS yggX NC_004431.1 3399952 3400227 D Escherichia coli K-12 ortholog: b2962; Escherichia coli O157:H7 ortholog: z4307; hypothetical protein 3399952..3400227 Escherichia coli CFT073 1039469 NP_755426.1 CDS mltC NC_004431.1 3400289 3401371 D Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 3400289..3401371 Escherichia coli CFT073 1039470 NP_755427.1 CDS nupG NC_004431.1 3401525 3402829 D Nucleoside-transport system protein nupG; Escherichia coli K-12 ortholog: b2964; Escherichia coli O157:H7 ortholog: z4309; nucleoside permease nupG 3401525..3402829 Escherichia coli CFT073 1039472 NP_755428.1 CDS speC NC_004431.1 3402878 3405013 R Escherichia coli K-12 ortholog: b2965; Escherichia coli O157:H7 ortholog: z4310; ornithine decarboxylase complement(3402878..3405013) Escherichia coli CFT073 1039473 NP_755429.1 CDS c3554 NC_004431.1 3405094 3405297 R hypothetical protein complement(3405094..3405297) Escherichia coli CFT073 1039474 NP_755430.1 CDS yqgA NC_004431.1 3405412 3406119 D Escherichia coli K-12 ortholog: b2966; Escherichia coli O157:H7 ortholog: z4311; hypothetical protein 3405412..3406119 Escherichia coli CFT073 1039475 NP_755431.1 CDS c3556 NC_004431.1 3406498 3407763 D Int(P4); Escherichia coli K-12 ortholog: b4271; Escherichia coli O157:H7 ortholog: z4313; prophage P4 integrase 3406498..3407763 Escherichia coli CFT073 1039478 NP_755432.1 CDS c3557 NC_004431.1 3408019 3409062 D Residues 1 to 347 of 347 are 83.28 pct identical to residues 1 to 347 of 347 from GenPept.129 : >gb|AAD44731.1|AF141323_2 (AF141323) ShiA [Shigella flexneri]; ShiA-like protein 3408019..3409062 Escherichia coli CFT073 1039480 NP_755433.1 CDS c3558 NC_004431.1 3409205 3409423 D hypothetical protein 3409205..3409423 Escherichia coli CFT073 1039482 NP_755434.1 CDS c3559 NC_004431.1 3409389 3410474 R Escherichia coli K-12 B4275 pseudogene; Residues 43 to 325 of 361 are 91.16 pct identical to residues 89 to 371 of 371 from SwissProt.40 : >sp|P39349|YJGX_ECOLI HYPOTHETICAL PROTEIN YJGX PRECURSOR; hypothetical protein complement(3409389..3410474) Escherichia coli CFT073 1039483 NP_755435.1 CDS c3560 NC_004431.1 3410473 3410877 D Escherichia coli O157:H7 ortholog: z5096; hypothetical protein 3410473..3410877 Escherichia coli CFT073 1039484 NP_755436.1 CDS c3561 NC_004431.1 3410874 3411221 D Escherichia coli O157:H7 ortholog: z4336; hypothetical protein 3410874..3411221 Escherichia coli CFT073 1039485 NP_755437.1 CDS c3562 NC_004431.1 3411270 3411677 D Residues 1 to 135 of 135 are 83.70 pct identical to residues 1 to 135 of 461 from GenPept.129 : >gb|AAL08460.1|AF326777_35 (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 3411270..3411677 Escherichia coli CFT073 1039486 NP_755438.1 CDS c3563 NC_004431.1 3411690 3412808 D Escherichia coli O157:H7 ortholog: z5098; hypothetical protein 3411690..3412808 Escherichia coli CFT073 1039487 NP_755439.1 CDS c3564 NC_004431.1 3413218 3414690 R Residues 169 to 490 of 490 are 26.31 pct identical to residues 162 to 473 of 475 from GenPept.129 : >gb|AAK81155.1|AE007818_1 (AE007818) Membrane associated histidine kinase with HAMP domain [Clostridium acetobutylicum]; hypothetical protein complement(3413218..3414690) Escherichia coli CFT073 1039488 NP_755440.1 CDS c3565 NC_004431.1 3414691 3415413 R Residues 6 to 232 of 240 are 47.16 pct identical to residues 12 to 240 of 247 from GenPept.129 : >gb|AAD36722.1|AE001807_13 (AE001807) response regulator DrrA [Thermotoga maritima]; response regulator complement(3414691..3415413) Escherichia coli CFT073 1039491 NP_755441.1 CDS c3566 NC_004431.1 3415551 3415946 D Residues 5 to 128 of 131 are 50.00 pct identical to residues 18 to 141 of 212 from GenPept.129 : >emb|CAD14149.1| (AL646060) TRANSMEMBRANE HYDROGENASE CYTOCHROME B-TYPE SUBUNIT OXIDOREDUCTASE PROTEIN [Ralstonia solanacearum]; hypothetical protein 3415551..3415946 Escherichia coli CFT073 1039492 NP_755442.1 CDS c3567 NC_004431.1 3416056 3416892 D Residues 42 to 278 of 278 are 54.20 pct identical to residues 11 to 248 of 257 from GenPept.129 : >emb|CAD14150.1| (AL646060) CONSERVED HYPOTHETICAL PROTEIN [Ralstonia solanacearum]; hypothetical protein 3416056..3416892 Escherichia coli CFT073 1039493 NP_755443.1 CDS c3568 NC_004431.1 3416947 3417189 D hypothetical protein 3416947..3417189 Escherichia coli CFT073 1039494 NP_755444.1 CDS hlyC NC_004431.1 3418210 3418884 D Residues 55 to 224 of 224 are 97.64 pct identical to residues 1 to 170 of 170 from SwissProt.40 : >sp|P09984|HLC1_ECOLI HEMOLYSIN-ACTIVATING LYSINE-ACYLTRANSFERASE HLYC (TOXIN-ACTIVATING PROTEIN C, J96) (HEMOLYSIN C); hemolysin C 3418210..3418884 Escherichia coli CFT073 1039495 NP_755445.1 CDS hlyA NC_004431.1 3418896 3421970 D Residues 1 to 1024 of 1024 are 98.63 pct identical to residues 1 to 1023 of 1023 from SwissProt.40 : >sp|P09983|HLY1_ECOLI HEMOLYSIN, CHROMOSOMAL; hemolysin A 3418896..3421970 Escherichia coli CFT073 1039496 NP_755446.1 CDS c3571 NC_004431.1 3421458 3421610 R hypothetical protein complement(3421458..3421610) Escherichia coli CFT073 1039498 NP_755447.1 CDS c3572 NC_004431.1 3421802 3422014 R hypothetical protein complement(3421802..3422014) Escherichia coli CFT073 1039500 NP_755448.1 CDS hlyB NC_004431.1 3422041 3424164 D Residues 1 to 707 of 707 are 99.57 pct identical to residues 1 to 707 of 707 from SwissProt.40 : >sp|P10089|HLY2_ECOLI Hemolysin secretion ATP-binding protein, chromosomal; hemolysin B 3422041..3424164 Escherichia coli CFT073 1039501 NP_755449.1 CDS hlyD NC_004431.1 3424183 3425619 D Residues 1 to 478 of 478 are 98.95 pct identical to residues 1 to 478 of 478 from SwissProt.40 : >sp|P09986|HLY4_ECOLI Hemolysin secretion protein D, chromosomal; hemolysin D 3424183..3425619 Escherichia coli CFT073 1039502 NP_755450.1 CDS c3575 NC_004431.1 3425931 3426749 R Escherichia coli K-12 ortholog: b2089; Escherichia coli O157:H7 ortholog: z1573; transposase insF complement(3425931..3426749) Escherichia coli CFT073 1039504 NP_755451.1 CDS c3576 NC_004431.1 3426785 3427087 R Escherichia coli O157:H7 ortholog: z1589; hypothetical protein complement(3426785..3427087) Escherichia coli CFT073 1039510 NP_755452.1 CDS c3577 NC_004431.1 3427169 3427570 D Escherichia coli O157:H7 ortholog: z5096; hypothetical protein 3427169..3427570 Escherichia coli CFT073 1039511 NP_755453.1 CDS c3578 NC_004431.1 3427567 3427914 D Escherichia coli O157:H7 ortholog: z5097; hypothetical protein 3427567..3427914 Escherichia coli CFT073 1039512 NP_755454.1 CDS c3579 NC_004431.1 3427962 3428432 R Residues 118 to 151 of 156 are 97.05 pct identical to residues 36 to 69 of 95 from GenPept.129 : >emb|CAC81894.1| (AJ277443) ST56 protein [Escherichia coli]; hypothetical protein complement(3427962..3428432) Escherichia coli CFT073 1039513 NP_755455.1 CDS c3580 NC_004431.1 3427964 3428356 D Residues 1 to 108 of 130 are 100.00 pct identical to residues 1 to 108 of 461 from GenPept.129 : >gb|AAL08460.1|AF326777_35 (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 3427964..3428356 Escherichia coli CFT073 1039514 NP_755456.1 CDS c3581 NC_004431.1 3428529 3428678 R hypothetical protein complement(3428529..3428678) Escherichia coli CFT073 1039515 NP_755457.1 CDS papX NC_004431.1 3428779 3429330 R Residues 18 to 183 of 183 are 96.38 pct identical to residues 1 to 166 of 166 from SwissProt.40 : >sp|P42192|PRSX_ECOLI PRSX PROTEIN; PapX protein complement(3428779..3429330) Escherichia coli CFT073 1039516 NP_755458.1 CDS papG NC_004431.1 3429593 3430603 R Residues 1 to 336 of 336 are 57.01 pct identical to residues 1 to 335 of 335 from SwissProt.40 : >sp|P42188|PRSG_ECOLI FIMBRIAL PROTEIN PRSG PRECURSOR (ADHESIN); PapG protein complement(3429593..3430603) Escherichia coli CFT073 1039518 NP_755459.1 CDS papF NC_004431.1 3430647 3431177 R Residues 11 to 176 of 176 are 92.81 pct identical to residues 1 to 167 of 167 from SwissProt.40 : >sp|P42187|PRSF_ECOLI MINOR FIMBRIAL PROTEIN PRSF PRECURSOR; PapF protein complement(3430647..3431177) Escherichia coli CFT073 1039519 NP_755460.1 CDS papE NC_004431.1 3431222 3431761 R Residues 7 to 179 of 179 are 91.32 pct identical to residues 1 to 173 of 173 from SwissProt.40 : >sp|P08407|PAPE_ECOLI FIMBRIAL PROTEIN PAPE PRECURSOR; PapE protein complement(3431222..3431761) Escherichia coli CFT073 1039520 NP_755461.1 CDS papK NC_004431.1 3431770 3432309 R Residues 2 to 179 of 179 are 100.00 pct identical to residues 1 to 178 of 178 from SwissProt.40 : >sp|P42190|PAPK_ECOLI PROTEIN PAPK PRECURSOR; PapK protein complement(3431770..3432309) Escherichia coli CFT073 1039523 NP_755462.1 CDS c3587 NC_004431.1 3431915 3432529 D hypothetical protein 3431915..3432529 Escherichia coli CFT073 1039524 NP_755463.1 CDS papJ NC_004431.1 3432316 3432897 R Residues 1 to 193 of 193 are 96.37 pct identical to residues 1 to 193 of 193 from SwissProt.40 : >sp|P42189|PRSJ_ECOLI PRSJ PROTEIN PRECURSOR; PapJ protein complement(3432316..3432897) Escherichia coli CFT073 1039525 NP_755464.1 CDS papD NC_004431.1 3432934 3433539 R Residues 1 to 201 of 201 are 41.58 pct identical to residues 46 to 246 of 250 from MG1655 : b2336; PapD protein complement(3432934..3433539) Escherichia coli CFT073 1039526 NP_755465.1 CDS papC NC_004431.1 3433739 3436261 R Residues 5 to 836 of 840 are 43.20 pct identical to residues 1 to 842 of 879 from EDL933 : z3600; PapC protein complement(3433739..3436261) Escherichia coli CFT073 1039527 NP_755466.1 CDS papH NC_004431.1 3436308 3436895 R Residues 1 to 195 of 195 are 98.97 pct identical to residues 1 to 195 of 195 from SwissProt.40 : >sp|P42185|PRSH_ECOLI PRS FIMBRIAL MINOR PILIN PROTEIN PRECURSOR; PapH protein complement(3436308..3436895) Escherichia coli CFT073 1039529 NP_755467.1 CDS papA NC_004431.1 3436965 3437564 R Residues 12 to 199 of 199 are 100.00 pct identical to residues 1 to 188 of 188 from SwissProt.40 : >sp|P02972|FMF2_ECOLI F7-2 FIMBRIAL PROTEIN PRECURSOR (F7-2 PILIN); PapA protein complement(3436965..3437564) Escherichia coli CFT073 1039530 NP_755468.1 CDS papI NC_004431.1 3438457 3438690 D Residues 1 to 77 of 77 are 98.70 pct identical to residues 1 to 77 of 77 from SwissProt.40 : >sp|P25395|KS7A_ECOLI P FIMBRIAL REGULATORY PROTEIN KS71A; PapI protein 3438457..3438690 Escherichia coli CFT073 1039535 NP_755469.1 CDS c3594 NC_004431.1 3439254 3439772 R Escherichia coli O157:H7 ortholog: z5880; transposase complement(3439254..3439772) Escherichia coli CFT073 1039536 NP_755470.1 CDS c3595 NC_004431.1 3439784 3440140 R Residues 1 to 118 of 118 are 98.30 pct identical to residues 1 to 118 of 118 from GenPept.129 : >gb|AAC61721.1| (AF081285) transposase R14 [Escherichia coli]; transposase complement(3439784..3440140) Escherichia coli CFT073 1039537 NP_755471.1 CDS c3596 NC_004431.1 3440140 3440466 R Escherichia coli O157:H7 ortholog: z5879; hypothetical protein complement(3440140..3440466) Escherichia coli CFT073 1039538 NP_755472.1 CDS c3597 NC_004431.1 3441312 3441902 R Residues 1 to 196 of 196 are 83.16 pct identical to residues 173 to 368 of 406 from GenPept.129 : >gb|AAF60967.1|AF188737_2 (AF188737) transposase [Escherichia coli]; transposase complement(3441312..3441902) Escherichia coli CFT073 1039539 NP_755473.1 CDS c3598 NC_004431.1 3441905 3442066 R hypothetical protein complement(3441905..3442066) Escherichia coli CFT073 1039540 NP_755474.1 CDS c3599 NC_004431.1 3442496 3442756 D Residues 1 to 86 of 86 are 100.00 pct identical to residues 1 to 86 of 86 from GenPept.129 : >gb|AAC61724.1| (AF081285) R10 [Escherichia coli]; hypothetical protein 3442496..3442756 Escherichia coli CFT073 1039541 NP_755475.1 CDS c3600 NC_004431.1 3442798 3443358 D Residues 3 to 165 of 186 are 27.54 pct identical to residues 7 to 173 of 201 from GenPept.129 : >dbj|BAB76266.1| (AP003596) transcriptional regulator [Nostoc sp. PCC 7120]; hypothetical protein 3442798..3443358 Escherichia coli CFT073 1039542 NP_755476.1 CDS c3601 NC_004431.1 3443368 3443826 D Residues 11 to 152 of 152 are 100.00 pct identical to residues 1 to 142 of 142 from GenPept.129 : >gb|AAC61725.1| (AF081285) F200 [Escherichia coli]; hypothetical protein 3443368..3443826 Escherichia coli CFT073 1039544 NP_755477.1 CDS c3602 NC_004431.1 3444379 3444594 R hypothetical protein complement(3444379..3444594) Escherichia coli CFT073 1039547 NP_755478.1 CDS c3603 NC_004431.1 3444598 3444981 R hypothetical protein complement(3444598..3444981) Escherichia coli CFT073 1039548 NP_755479.1 CDS c3604 NC_004431.1 3444661 3445062 D hypothetical protein 3444661..3445062 Escherichia coli CFT073 1039549 NP_755480.1 CDS c3605 NC_004431.1 3444978 3445169 R hypothetical protein complement(3444978..3445169) Escherichia coli CFT073 1039550 NP_755481.1 CDS c3606 NC_004431.1 3445257 3445577 R hypothetical protein complement(3445257..3445577) Escherichia coli CFT073 1039551 NP_755482.1 CDS c3607 NC_004431.1 3445858 3447357 D Residues 7 to 492 of 499 are 40.77 pct identical to residues 10 to 495 of 504 from SwissProt.40 : >sp|P55501|Y4JA_RHISN HYPOTHETICAL 57.2 KD PROTEIN Y4JA/Y4NE/Y4SE; hypothetical protein 3445858..3447357 Escherichia coli CFT073 1039553 NP_755483.1 CDS c3608 NC_004431.1 3447354 3448109 D Residues 1 to 244 of 251 are 41.60 pct identical to residues 1 to 250 of 298 from SwissProt.40 : >sp|P55500|Y4IQ_RHISN INSERTION SEQUENCE ATP-BINDING PROTEIN Y4IQ/Y4ND/Y4SD; hypothetical protein 3447354..3448109 Escherichia coli CFT073 1039554 NP_755484.1 CDS c3609 NC_004431.1 3448318 3448542 R Residues 1 to 74 of 74 are 97.29 pct identical to residues 1 to 74 of 74 from GenPept.129 : >dbj|BAB34782.1| (AP002554) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein complement(3448318..3448542) Escherichia coli CFT073 1039556 NP_755485.1 CDS c3610 NC_004431.1 3448776 3450866 R IrgA-homologue adhesin (Iha); TonB-dependent; acts as a specific receptor of enterobactin; fur-regulated; urovirulence factor; bifunctional enterobactin receptor/adhesin protein complement(3448776..3450866) Escherichia coli CFT073 1039557 NP_755486.1 CDS c3611 NC_004431.1 3451366 3452271 R IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD complement(3451366..3452271) Escherichia coli CFT073 1039558 NP_755487.1 CDS c3612 NC_004431.1 3452264 3452638 R Escherichia coli K-12 ortholog: b4272; transposase insC complement(3452264..3452638) Escherichia coli CFT073 1039563 NP_755488.1 CDS c3613 NC_004431.1 3452810 3452968 D Residues 1 to 44 of 52 are 75.00 pct identical to residues 47 to 90 of 116 from GenPept.129 : >gb|AAG58804.1|AE005593_6 (AE005593) unknown protein encoded by IS911 within prophage CP-933L [Escherichia coli O157:H7 EDL933]; hypothetical protein 3452810..3452968 Escherichia coli CFT073 1039566 NP_755489.1 CDS c3614 NC_004431.1 3452972 3453157 R Residues 1 to 61 of 61 are 100.00 pct identical to residues 477 to 537 of 537 from GenPept.129 : >gb|AAG55715.1|AE005309_5 (AE005309) unknown in ISEc8 [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(3452972..3453157) Escherichia coli CFT073 1039567 NP_755490.1 CDS c3615 NC_004431.1 3453103 3454584 R Escherichia coli O157:H7 ortholog: z1600; hypothetical protein complement(3453103..3454584) Escherichia coli CFT073 1039568 NP_755491.1 CDS c3616 NC_004431.1 3454615 3454965 R Escherichia coli O157:H7 ortholog: z1599; hypothetical protein complement(3454615..3454965) Escherichia coli CFT073 1039570 NP_755492.1 CDS c3617 NC_004431.1 3454962 3455399 R Escherichia coli O157:H7 ortholog: z1648; hypothetical protein complement(3454962..3455399) Escherichia coli CFT073 1039571 NP_755493.1 CDS c3618 NC_004431.1 3455734 3456432 R Residues 40 to 232 of 232 are 98.44 pct identical to residues 1 to 193 of 193 from GenPept.129 : >gb|AAK00460.1| (AF200692) unknown [Shigella flexneri 2a]; hypothetical protein complement(3455734..3456432) Escherichia coli CFT073 1039572 NP_755494.1 CDS sat NC_004431.1 3456362 3460261 R Residues 5 to 1299 of 1299 are 100.00 pct identical to residues 1 to 1295 of 1295 from GenPept.129 : >gb|AAG30168.1|AF289092_1 (AF289092) secreted autotransporter toxin [Escherichia coli]; secreted auto transporter toxin complement(3456362..3460261) Escherichia coli CFT073 1039573 NP_755497.1 CDS c3622 NC_004431.1 3460499 3460642 D hypothetical protein 3460499..3460642 Escherichia coli CFT073 1039577 NP_755498.1 CDS iutA NC_004431.1 3461193 3463472 R Residues 28 to 759 of 759 are 87.56 pct identical to residues 2 to 732 of 732 from SwissProt.40 : >sp|P14542|IUTA_ECOLI FERRIC AEROBACTIN RECEPTOR PRECURSOR (CLOACIN RECEPTOR); IutA protein complement(3461193..3463472) Escherichia coli CFT073 1039578 NP_755499.1 CDS iucD NC_004431.1 3463394 3464731 R Residues 1 to 425 of 445 are 97.88 pct identical to residues 1 to 425 of 425 from SwissProt.40 : >sp|P11295|IUCD_ECOLI L-LYSINE 6-MONOOXYGENASE (LYSINE N6-HYDROXYLASE); IucD protein complement(3463394..3464731) Escherichia coli CFT073 1039579 NP_755500.1 CDS iucC NC_004431.1 3464728 3466470 R Residues 1 to 580 of 580 are 96.89 pct identical to residues 1 to 580 of 580 from SwissProt.40 : >sp|Q47318|IUCC_ECOLI AEROBACTIN SIDEROPHORE BIOSYNTHESIS PROTEIN IUCC; IucC protein complement(3464728..3466470) Escherichia coli CFT073 1039580 NP_755501.1 CDS iucB NC_004431.1 3466470 3467417 R Residues 1 to 315 of 315 are 94.92 pct identical to residues 1 to 315 of 315 from SwissProt.40 : >sp|Q47317|IUCB_ECOLI AEROBACTIN SIDEROPHORE BIOSYNTHESIS PROTEIN IUCB; IucB protein complement(3466470..3467417) Escherichia coli CFT073 1039581 NP_755502.1 CDS iucA NC_004431.1 3467418 3469205 R Residues 22 to 595 of 595 are 93.04 pct identical to residues 1 to 575 of 575 from SwissProt.40 : >sp|Q47316|IUCA_ECOLI AEROBACTIN SIDEROPHORE BIOSYNTHESIS PROTEIN IUCA; IucA protein complement(3467418..3469205) Escherichia coli CFT073 1039582 NP_755503.1 CDS shiF NC_004431.1 3469278 3470471 D Residues 1 to 397 of 397 are 99.74 pct identical to residues 1 to 397 of 397 from GenPept.129 : >gb|AAD44744.1|AF141323_15 (AF141323) ShiF [Shigella flexneri]; shiF protein 3469278..3470471 Escherichia coli CFT073 1039583 NP_755504.1 CDS c3629 NC_004431.1 3469679 3469801 R hypothetical protein complement(3469679..3469801) Escherichia coli CFT073 1039586 NP_755505.1 CDS c3630 NC_004431.1 3470630 3471619 R Escherichia coli K-12 ortholog: b4309; hypothetical protein complement(3470630..3471619) Escherichia coli CFT073 1039587 NP_755506.1 CDS c3631 NC_004431.1 3471917 3472081 R hypothetical protein complement(3471917..3472081) Escherichia coli CFT073 1039589 NP_755507.1 CDS c3632 NC_004431.1 3472357 3472488 R hypothetical protein complement(3472357..3472488) Escherichia coli CFT073 1039590 NP_755508.1 CDS c3633 NC_004431.1 3472475 3473413 R Residues 55 to 310 of 312 are 37.89 pct identical to residues 73 to 327 of 328 from GenPept.129 : >gb|AAK24284.1| (AE005901) hypothetical protein [Caulobacter crescentus CB15]; hypothetical protein complement(3472475..3473413) Escherichia coli CFT073 1039591 NP_755509.1 CDS c3634 NC_004431.1 3473463 3474581 R Escherichia coli K-12 ortholog: b4310; Escherichia coli O157:H7 ortholog: z5906; N-acetylneuraminic acid mutarotase complement(3473463..3474581) Escherichia coli CFT073 1039593 NP_755510.1 CDS c3635 NC_004431.1 3474585 3475325 R Escherichia coli K-12 ortholog: b4311; Escherichia coli O157:H7 ortholog: z5907; hypothetical protein complement(3474585..3475325) Escherichia coli CFT073 1039594 NP_755511.1 CDS c3636 NC_004431.1 3475341 3476150 R Residues 37 to 266 of 269 are 40.65 pct identical to residues 81 to 326 of 328 from GenPept.129 : >gb|AAK24284.1| (AE005901) hypothetical protein [Caulobacter crescentus CB15]; hypothetical protein complement(3475341..3476150) Escherichia coli CFT073 1039596 NP_755512.2 CDS c3637 NC_004431.1 3476175 3477647 R Escherichia coli K-12 ortholog: b3224; Escherichia coli O157:H7 ortholog: z4582; sialic acid transporter complement(3476175..3477647) Escherichia coli CFT073 1039597 NP_755513.1 CDS c3638 NC_004431.1 3477696 3478571 R catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase complement(3477696..3478571) Escherichia coli CFT073 1039598 NP_755514.1 CDS c3639 NC_004431.1 3478605 3479522 R catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase complement(3478605..3479522) Escherichia coli CFT073 1039599 NP_755515.1 CDS c3640 NC_004431.1 3480253 3480615 D Escherichia coli O157:H7 ortholog: z1598; hypothetical protein 3480253..3480615 Escherichia coli CFT073 1039601 NP_755516.1 CDS c3641 NC_004431.1 3480612 3480962 D Escherichia coli O157:H7 ortholog: z1599; hypothetical protein 3480612..3480962 Escherichia coli CFT073 1039602 NP_755517.1 CDS c3642 NC_004431.1 3480627 3480971 R hypothetical protein complement(3480627..3480971) Escherichia coli CFT073 1039603 NP_755518.1 CDS c3643 NC_004431.1 3480993 3482093 D Escherichia coli O157:H7 ortholog: z1600; hypothetical protein 3480993..3482093 Escherichia coli CFT073 1039604 NP_755519.1 CDS c3644 NC_004431.1 3481920 3482084 R hypothetical protein complement(3481920..3482084) Escherichia coli CFT073 1039605 NP_755520.1 CDS c3645 NC_004431.1 3482090 3483628 D Escherichia coli O157:H7 ortholog: z5098; hypothetical protein 3482090..3483628 Escherichia coli CFT073 1039607 NP_755521.1 CDS c3646 NC_004431.1 3483544 3483738 R Residues 26 to 64 of 64 are 100.00 pct identical to residues 89 to 127 of 127 from GenPept.129 : >gb|AAD30026.1|AF119170_1 (AF119170) truncated BfpA [Escherichia coli]; hypothetical protein complement(3483544..3483738) Escherichia coli CFT073 1039608 NP_755522.1 CDS c3647 NC_004431.1 3483812 3484267 R Residues 13 to 136 of 151 are 91.12 pct identical to residues 1 to 124 of 127 from GenPept.129 : >gb|AAK00467.1| (AF200692) unknown [Shigella flexneri 2a]; hypothetical protein complement(3483812..3484267) Escherichia coli CFT073 1039613 NP_755523.1 CDS c3648 NC_004431.1 3484397 3484966 R Residues 5 to 189 of 189 are 39.56 pct identical to residues 6 to 235 of 246 from GenPept.129 : >gb|AAL67401.1|AF447814_69 (AF447814) intergenic-region protein [Escherichia coli]; hypothetical protein complement(3484397..3484966) Escherichia coli CFT073 1039616 NP_755524.1 CDS c3649 NC_004431.1 3485694 3485918 R Escherichia coli K-12 ortholog: b0460; Escherichia coli O157:H7 ortholog: z0573; hemolysin expression modulating protein complement(3485694..3485918) Escherichia coli CFT073 1039618 NP_755525.1 CDS c3650 NC_004431.1 3486747 3487007 D Residues 11 to 86 of 86 are 96.05 pct identical to residues 17 to 92 of 92 from GenPept.129 : >gb|AAL08466.1| (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 3486747..3487007 Escherichia coli CFT073 1039619 NP_755526.1 CDS c3651 NC_004431.1 3487066 3487665 D Residues 28 to 199 of 199 are 97.67 pct identical to residues 1 to 172 of 172 from GenPept.129 : >gb|AAK00471.1| (AF200692) unknown [Shigella flexneri 2a]; hypothetical protein 3487066..3487665 Escherichia coli CFT073 1039621 NP_755527.1 CDS c3652 NC_004431.1 3487786 3489294 R Escherichia coli K-12 ortholog: b2625; hypothetical protein complement(3487786..3489294) Escherichia coli CFT073 1039622 NP_755528.1 CDS c3653 NC_004431.1 3489471 3489692 R hypothetical protein complement(3489471..3489692) Escherichia coli CFT073 1039646 NP_755529.1 CDS c3654 NC_004431.1 3490608 3491480 D Escherichia coli K-12 ortholog: b1999; Escherichia coli O157:H7 ortholog: z1650; hypothetical protein 3490608..3491480 Escherichia coli CFT073 1039679 NP_755530.1 CDS c3655 NC_004431.1 3491808 3494936 D AG43; Sap; Escherichia coli K-12 ortholog: b2000; Escherichia coli O157:H7 ortholog: z1651; antigen 43 3491808..3494936 Escherichia coli CFT073 1039680 NP_755531.1 CDS c3656 NC_004431.1 3495115 3495444 D Residues 1 to 109 of 109 are 68.80 pct identical to residues 1 to 109 of 109 from GenPept.129 : >dbj|BAB34765.1| (AP002554) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein 3495115..3495444 Escherichia coli CFT073 1039681 NP_755532.1 CDS c3657 NC_004431.1 3495431 3495823 D Escherichia coli O157:H7 ortholog: z1602; hypothetical protein 3495431..3495823 Escherichia coli CFT073 1039682 NP_755533.1 CDS c3658 NC_004431.1 3495830 3497431 D Residues 13 to 298 of 533 are 71.32 pct identical to residues 1 to 277 of 285 from GenPept.129 : >gb|AAG55716.1|AE005309_6 (AE005309) unknown in ISEc8 [Escherichia coli O157:H7 EDL933]; hypothetical protein 3495830..3497431 Escherichia coli CFT073 1039683 NP_755534.1 CDS c3659 NC_004431.1 3497824 3498471 D Escherichia coli O157:H7 ortholog: z4315; hypothetical protein 3497824..3498471 Escherichia coli CFT073 1039684 NP_755535.1 CDS c3660 NC_004431.1 3498471 3498818 D Escherichia coli O157:H7 ortholog: z4316; hypothetical protein 3498471..3498818 Escherichia coli CFT073 1039685 NP_755536.1 CDS c3661 NC_004431.1 3498552 3498731 R hypothetical protein complement(3498552..3498731) Escherichia coli CFT073 1039686 NP_755537.1 CDS c3662 NC_004431.1 3498838 3499941 D Escherichia coli O157:H7 ortholog: z4317; hypothetical protein 3498838..3499941 Escherichia coli CFT073 1039687 NP_755538.1 CDS c3663 NC_004431.1 3500024 3500404 D Residues 1 to 126 of 126 are 95.23 pct identical to residues 398 to 523 of 523 from GenPept.129 : >dbj|BAA84886.1| (AB024946) orf51 [Escherichia coli]; hypothetical protein 3500024..3500404 Escherichia coli CFT073 1039689 NP_755539.1 CDS c3664 NC_004431.1 3500527 3503049 D Escherichia coli K-12 ortholog: b2001; hypothetical protein 3500527..3503049 Escherichia coli CFT073 1039690 NP_755540.1 CDS c3665 NC_004431.1 3503125 3503580 D Residues 9 to 151 of 151 are 98.60 pct identical to residues 1 to 143 of 143 from GenPept.129 : >gb|AAK00476.1| (AF200692) unknown [Shigella flexneri 2a]; hypothetical protein 3503125..3503580 Escherichia coli CFT073 1039691 NP_755541.1 CDS c3666 NC_004431.1 3503659 3503892 D Escherichia coli K-12 ortholog: b0249; hypothetical protein 3503659..3503892 Escherichia coli CFT073 1039695 NP_755542.1 CDS c3667 NC_004431.1 3503701 3503889 R hypothetical protein complement(3503701..3503889) Escherichia coli CFT073 1039696 NP_755543.1 CDS c3668 NC_004431.1 3503993 3504811 D Escherichia coli K-12 ortholog: b0252; Escherichia coli O157:H7 ortholog: z1655; hypothetical protein 3503993..3504811 Escherichia coli CFT073 1039697 NP_755544.1 CDS c3669 NC_004431.1 3504866 3505351 D Escherichia coli K-12 ortholog: b2643; Escherichia coli O157:H7 ortholog: z1656; hypothetical protein 3504866..3505351 Escherichia coli CFT073 1039698 NP_755545.1 CDS c3670 NC_004431.1 3504920 3505831 R Residues 1 to 298 of 303 are 93.28 pct identical to residues 1 to 298 of 319 from GenPept.129 : >gb|AAL67347.1|AF447814_15 (AF447814) unknown [Escherichia coli]; hypothetical protein complement(3504920..3505831) Escherichia coli CFT073 1039700 NP_755546.1 CDS c3671 NC_004431.1 3505352 3505843 D Escherichia coli K-12 ortholog: b2002; Escherichia coli O157:H7 ortholog: z1217; radC-like protein yeeS 3505352..3505843 Escherichia coli CFT073 1039702 NP_755547.1 CDS c3672 NC_004431.1 3505840 3506568 R Residues 140 to 221 of 242 are 40.24 pct identical to residues 71 to 152 of 164 from GenPept.129 : >gb|AAB08666.1| (U70214) hypothetical protein [Escherichia coli]; hypothetical protein complement(3505840..3506568) Escherichia coli CFT073 1039703 NP_755548.1 CDS c3673 NC_004431.1 3505906 3506127 D Escherichia coli K-12 ortholog: b2003; Escherichia coli O157:H7 ortholog: z3163; hypothetical protein 3505906..3506127 Escherichia coli CFT073 1039705 NP_755549.1 CDS c3674 NC_004431.1 3506146 3506790 D Residues 178 to 214 of 214 are 78.37 pct identical to residues 1 to 37 of 37 from GenPept.129 : >gb|AAL57577.1|AF453442_6 (AF453442) unknown [Escherichia coli]; hypothetical protein 3506146..3506790 Escherichia coli CFT073 1039706 NP_755550.1 CDS c3675 NC_004431.1 3506813 3507376 R Residues 92 to 160 of 187 are 82.60 pct identical to residues 1 to 69 of 176 from GenPept.129 : >gb|AAL67390.1|AF447814_58 (AF447814) unknown [Escherichia coli]; hypothetical protein complement(3506813..3507376) Escherichia coli CFT073 1039709 NP_755551.1 CDS c3676 NC_004431.1 3506840 3507220 D Escherichia coli K-12 ortholog: b2004; Escherichia coli O157:H7 ortholog: z3164; hypothetical protein 3506840..3507220 Escherichia coli CFT073 1039710 NP_755552.1 CDS c3677 NC_004431.1 3507297 3507674 D Escherichia coli K-12 ortholog: b2005; Escherichia coli O157:H7 ortholog: z5091; hypothetical protein 3507297..3507674 Escherichia coli CFT073 1039711 NP_755553.1 CDS c3678 NC_004431.1 3507671 3508159 D Escherichia coli O157:H7 ortholog: z1662; hypothetical protein 3507671..3508159 Escherichia coli CFT073 1039713 NP_755554.1 CDS c3679 NC_004431.1 3508176 3508373 D Escherichia coli O157:H7 ortholog: z1663; hypothetical protein 3508176..3508373 Escherichia coli CFT073 1039715 NP_755555.1 CDS c3680 NC_004431.1 3508458 3509303 D Escherichia coli O157:H7 ortholog: z1664; hypothetical protein 3508458..3509303 Escherichia coli CFT073 1039716 NP_755556.1 CDS c3681 NC_004431.1 3509372 3509767 D hypothetical protein 3509372..3509767 Escherichia coli CFT073 1039720 NP_755557.1 CDS c3682 NC_004431.1 3509760 3510677 D hypothetical protein 3509760..3510677 Escherichia coli CFT073 1039721 NP_755558.1 CDS c3683 NC_004431.1 3510482 3510694 D hypothetical protein 3510482..3510694 Escherichia coli CFT073 1039722 NP_755559.1 CDS c3684 NC_004431.1 3511126 3511281 D Residues 9 to 51 of 51 are 76.74 pct identical to residues 64 to 106 of 112 from GenPept.129 : >gb|AAK18488.1|AF348706_177 (AF348706) transposase [Shigella flexneri]; hypothetical protein 3511126..3511281 Escherichia coli CFT073 1039723 NP_755560.1 CDS c3685 NC_004431.1 3511449 3511592 R hypothetical protein complement(3511449..3511592) Escherichia coli CFT073 1039724 NP_755561.1 CDS c3686 NC_004431.1 3512056 3513075 D Escherichia coli K-12 ortholog: b3197; Escherichia coli O157:H7 ortholog: z4560; hypothetical protein 3512056..3513075 Escherichia coli CFT073 1039725 NP_755562.1 CDS kpsE NC_004431.1 3513147 3514295 D Residues 1 to 382 of 382 are 100.00 pct identical to residues 1 to 382 of 382 from SwissProt.40 : >sp|P42214|KSE5_ECOLI CAPSULE POLYSACCHARIDE EXPORT INNER-MEMBRANE PROTEIN KPSE; KpsE protein 3513147..3514295 Escherichia coli CFT073 1039726 NP_755563.1 CDS kpsD NC_004431.1 3514316 3515995 D Residues 2 to 559 of 559 are 99.46 pct identical to residues 1 to 558 of 558 from SwissProt.40 : >sp|P42213|KSD5_ECOLI POLYSIALIC ACID TRANSPORT PROTEIN KPSD PRECURSOR; KpsD protein 3514316..3515995 Escherichia coli CFT073 1039727 NP_755564.1 CDS c3689 NC_004431.1 3516005 3516745 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 3516005..3516745 Escherichia coli CFT073 1039728 NP_755565.1 CDS kpsC NC_004431.1 3516742 3518769 D Residues 1 to 675 of 675 are 96.29 pct identical to residues 1 to 675 of 675 from SwissProt.40 : >sp|P42217|KSC5_ECOLI Capsule polysaccharide export protein KPSC; KpsC protein 3516742..3518769 Escherichia coli CFT073 1039730 NP_755566.1 CDS kpsS NC_004431.1 3518804 3520042 D Residues 1 to 389 of 412 are 97.17 pct identical to residues 1 to 389 of 389 from SwissProt.40 : >sp|P42218|KSS5_ECOLI CAPSULE POLYSACCHARIDE EXPORT PROTEIN KPSS; KpsS protein 3518804..3520042 Escherichia coli CFT073 1039731 NP_755567.1 CDS c3692 NC_004431.1 3520204 3521199 R hypothetical protein complement(3520204..3521199) Escherichia coli CFT073 1039732 NP_755568.1 CDS c3693 NC_004431.1 3521205 3522233 R Residues 11 to 332 of 342 are 23.26 pct identical to residues 225 to 543 of 543 from GenPept.129 : >gb|AAK05018.1|AE006326_9 (AE006326) UNKNOWN PROTEIN [Lactococcus lactis subsp. lactis]; hypothetical protein complement(3521205..3522233) Escherichia coli CFT073 1039733 NP_755569.1 CDS c3694 NC_004431.1 3522336 3526136 R Residues 495 to 1078 of 1266 are 33.16 pct identical to residues 10 to 602 of 807 from GenPept.129 : >gb|AAK05019.1|AE006326_10 (AE006326) teichoic acid biosynthesis protein [Lactococcus lactis subsp. lactis]; hypothetical protein complement(3522336..3526136) Escherichia coli CFT073 1039734 NP_755570.1 CDS c3695 NC_004431.1 3526190 3527425 R Residues 210 to 367 of 411 are 29.10 pct identical to residues 50 to 232 of 246 from GenPept.129 : >dbj|BAB80328.1| (AP003187) hypothetical protein [Clostridium perfringens]; hypothetical protein complement(3526190..3527425) Escherichia coli CFT073 1039735 NP_755571.1 CDS c3696 NC_004431.1 3527441 3527848 R Residues 5 to 131 of 135 are 49.60 pct identical to residues 1 to 126 of 129 from SwissProt.40 : >sp|P27623|TAGD_BACSU Glycerol-3-phosphate cytidylyltransferase (GCT) (CDP-glycerol pyrophosphorylase) (Teichoic acid biosynthesis protein D); glycerol-3-phosphate cytidyltransferase complement(3527441..3527848) Escherichia coli CFT073 1039736 NP_755572.1 CDS kpsT NC_004431.1 3527848 3528519 R Residues 1 to 223 of 223 are 88.78 pct identical to residues 1 to 223 of 224 from SwissProt.40 : >sp|P24586|KST5_ECOLI POLYSIALIC ACID TRANSPORT ATP-BINDING PROTEIN KPST; KpsT protein complement(3527848..3528519) Escherichia coli CFT073 1039737 NP_755573.1 CDS kpsM NC_004431.1 3528516 3529292 R Residues 1 to 258 of 258 are 96.89 pct identical to residues 1 to 258 of 258 from SwissProt.40 : >sp|P24584|KPM2_ECOLI POLYSIALIC ACID TRANSPORT PROTEIN KPSM; KpsM protein complement(3528516..3529292) Escherichia coli CFT073 1039739 NP_755574.1 CDS yghD NC_004431.1 3530466 3531002 R Escherichia coli K-12 ortholog: b2968; general secretion pathway protein YghD complement(3530466..3531002) Escherichia coli CFT073 1039740 NP_755575.1 CDS c3702 NC_004431.1 3532178 3532591 R Residues 1 to 137 of 137 are 98.54 pct identical to residues 189 to 325 of 325 from GenPept.129 : >gb|AAL60191.1|AF426313_11 (AF426313) hypothetical type II secretion protein GspK [Escherichia coli]; hypothetical protein complement(3532178..3532591) Escherichia coli CFT073 1039744 NP_755576.1 CDS c3703 NC_004431.1 3532771 3534120 R Escherichia coli K-12 ortholog: b4278; transposase insG complement(3532771..3534120) Escherichia coli CFT073 1039745 NP_755577.1 CDS yghK NC_004431.1 3534256 3535938 R Escherichia coli K-12 ortholog: b2975; Escherichia coli O157:H7 ortholog: z5030; glycolate transporter complement(3534256..3535938) Escherichia coli CFT073 1039746 NP_755578.1 CDS glcB NC_004431.1 3536293 3538464 R catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G complement(3536293..3538464) Escherichia coli CFT073 1039747 NP_755579.1 CDS glcG NC_004431.1 3538486 3538908 R Escherichia coli K-12 ortholog: b2977; hypothetical protein complement(3538486..3538908) Escherichia coli CFT073 1039748 NP_755580.1 CDS glcD NC_004431.1 3541181 3542680 R Escherichia coli K-12 ortholog: b2979; glycolate oxidase subunit GlcD complement(3541181..3542680) Escherichia coli CFT073 1039751 NP_755581.1 CDS glcC NC_004431.1 3542871 3543695 D Escherichia coli K-12 ortholog: b2980; DNA-binding transcriptional regulator GlcC 3542871..3543695 Escherichia coli CFT073 1039754 NP_755582.1 CDS yghO NC_004431.1 3543702 3544910 R Fragment; Escherichia coli K-12 ortholog: b2981; hypothetical protein complement(3543702..3544910) Escherichia coli CFT073 1039755 NP_755583.1 CDS c3712 NC_004431.1 3545212 3546942 D activates fatty acids by binding to coenzyme A; acyl-CoA synthetase 3545212..3546942 Escherichia coli CFT073 1039758 NP_755584.1 CDS c3713 NC_004431.1 3546939 3547853 D Residues 5 to 287 of 304 are 33.21 pct identical to residues 9 to 288 of 317 from GenPept.129 : >gb|AAK23148.1| (AE005794) conserved hypothetical protein [Caulobacter crescentus CB15]; hypothetical protein 3546939..3547853 Escherichia coli CFT073 1039760 NP_755585.1 CDS c3714 NC_004431.1 3547885 3548133 D hypothetical protein 3547885..3548133 Escherichia coli CFT073 1039764 NP_755586.1 CDS c3715 NC_004431.1 3548133 3549305 D Residues 1 to 388 of 390 are 53.47 pct identical to residues 1 to 389 of 404 from GenPept.129 : >gb|AAK23146.1| (AE005794) aminotransferase, class II [Caulobacter crescentus CB15]; hypothetical protein 3548133..3549305 Escherichia coli CFT073 1039767 NP_755587.1 CDS c3716 NC_004431.1 3549340 3550500 R Residues 30 to 379 of 386 are 29.17 pct identical to residues 4 to 354 of 358 from GenPept.129 : >emb|CAC92669.1| (AJ414157) membrane protein [Yersinia pestis]; hypothetical protein complement(3549340..3550500) Escherichia coli CFT073 1039768 NP_755588.1 CDS c3717 NC_004431.1 3550416 3551486 R Residues 3 to 342 of 356 are 29.54 pct identical to residues 2 to 350 of 372 from GenPept.129 : >gb|AAG07215.1|AE004800_4 (AE004800) conserved hypothetical protein [Pseudomonas aeruginosa]; hypothetical protein complement(3550416..3551486) Escherichia coli CFT073 1039775 NP_755589.1 CDS c3718 NC_004431.1 3551517 3552080 R Escherichia coli K-12 ortholog: b4216; Escherichia coli O157:H7 ortholog: z5827; hypothetical protein complement(3551517..3552080) Escherichia coli CFT073 1039776 NP_755590.1 CDS c3719 NC_004431.1 3552089 3552913 R hypothetical protein complement(3552089..3552913) Escherichia coli CFT073 1039777 NP_755591.1 CDS yghQ NC_004431.1 3552913 3554262 R Escherichia coli K-12 ortholog: b2983; hypothetical protein complement(3552913..3554262) Escherichia coli CFT073 1039778 NP_755592.1 CDS yghR NC_004431.1 3554308 3555066 R Escherichia coli K-12 ortholog: b2984; ATP-binding protein yghR complement(3554308..3555066) Escherichia coli CFT073 1039780 NP_755593.1 CDS yghS NC_004431.1 3555098 3555811 R Escherichia coli K-12 ortholog: b2985; ATP-binding protein yghS complement(3555098..3555811) Escherichia coli CFT073 1039781 NP_755594.1 CDS yghT NC_004431.1 3555986 3556678 D Escherichia coli K-12 ortholog: b2986; ATP-binding protein yghT 3555986..3556678 Escherichia coli CFT073 1039782 NP_755595.1 CDS pitB NC_004431.1 3556727 3558226 R Escherichia coli K-12 ortholog: b2987; Escherichia coli O157:H7 ortholog: z4893; inorganic phosphate transporter complement(3556727..3558226) Escherichia coli CFT073 1039783 NP_755596.1 CDS gsp NC_004431.1 3558518 3560380 R catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase complement(3558518..3560380) Escherichia coli CFT073 1039784 NP_755597.1 CDS yghU NC_004431.1 3560534 3561448 D YghU; B2989; one of eight glutathione transferase proteins from E. coli; glutathione S-transferase YghU 3560534..3561448 Escherichia coli CFT073 1039785 NP_755598.1 CDS hybG NC_004431.1 3561590 3561838 R Escherichia coli K-12 ortholog: b2990; Escherichia coli O157:H7 ortholog: z4344; hydrogenase 2 accessory protein HypG complement(3561590..3561838) Escherichia coli CFT073 1039786 NP_755599.1 CDS hypA NC_004431.1 3561851 3562192 R plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF complement(3561851..3562192) Escherichia coli CFT073 1039787 NP_755600.1 CDS hybE NC_004431.1 3562185 3562673 R Escherichia coli K-12 ortholog: b2992; Escherichia coli O157:H7 ortholog: z4346; hydrogenase 2-specific chaperone complement(3562185..3562673) Escherichia coli CFT073 1039788 NP_755601.1 CDS hybD NC_004431.1 3562666 3563160 R protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase complement(3562666..3563160) Escherichia coli CFT073 1039789 NP_755602.1 CDS hybC NC_004431.1 3563160 3564863 R involved in hydrogen uptake; hydrogenase 2 large subunit complement(3563160..3564863) Escherichia coli CFT073 1039790 NP_755603.1 CDS hybB NC_004431.1 3564860 3566038 R HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; hydrogenase 2 b cytochrome subunit complement(3564860..3566038) Escherichia coli CFT073 1039791 NP_755604.1 CDS hybA NC_004431.1 3566028 3567014 R Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA complement(3566028..3567014) Escherichia coli CFT073 1039793 NP_755605.1 CDS c3734 NC_004431.1 3567017 3568135 R involved in hydrogen uptake; hydrogenase 2 small subunit complement(3567017..3568135) Escherichia coli CFT073 1039794 NP_755606.1 CDS yghW NC_004431.1 3568324 3568611 R Escherichia coli K-12 ortholog: b2998; Escherichia coli O157:H7 ortholog: z4352; hypothetical protein complement(3568324..3568611) Escherichia coli CFT073 1039795 NP_755607.1 CDS c3736 NC_004431.1 3568730 3569656 R Escherichia coli O157:H7 ortholog: z4353; hypothetical protein complement(3568730..3569656) Escherichia coli CFT073 1039796 NP_755608.1 CDS yghZ NC_004431.1 3569774 3570814 D Escherichia coli K-12 ortholog: b3001; Escherichia coli O157:H7 ortholog: z4354; aldo/keto reductase 3569774..3570814 Escherichia coli CFT073 1039797 NP_755609.1 CDS yqhA NC_004431.1 3570854 3571378 R Escherichia coli K-12 ortholog: b3002; Escherichia coli O157:H7 ortholog: z4355; hypothetical protein complement(3570854..3571378) Escherichia coli CFT073 1039798 NP_755610.1 CDS yghA NC_004431.1 3571536 3572423 D Escherichia coli K-12 ortholog: b3003; Escherichia coli O157:H7 ortholog: z4356; oxidoreductase 3571536..3572423 Escherichia coli CFT073 1039799 NP_755611.1 CDS exbD NC_004431.1 3572462 3572887 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD complement(3572462..3572887) Escherichia coli CFT073 1039801 NP_755612.1 CDS exbB NC_004431.1 3572894 3573628 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB complement(3572894..3573628) Escherichia coli CFT073 1039802 NP_755613.1 CDS metC NC_004431.1 3573745 3575067 D catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3573745..3575067 Escherichia coli CFT073 1039803 NP_755614.1 CDS yghB NC_004431.1 3575207 3575866 D Escherichia coli K-12 ortholog: b3009; Escherichia coli O157:H7 ortholog: z4362; hypothetical protein 3575207..3575866 Escherichia coli CFT073 1039804 NP_755615.1 CDS yqhC NC_004431.1 3575906 3577033 R Escherichia coli K-12 ortholog: b3010; Escherichia coli O157:H7 ortholog: z4363; transcriptional regulator YqhC complement(3575906..3577033) Escherichia coli CFT073 1039805 NP_755616.1 CDS yqhD NC_004431.1 3576999 3578162 D Escherichia coli K-12 ortholog: b3011; Escherichia coli O157:H7 ortholog: z4364; oxidoreductase yqhD 3576999..3578162 Escherichia coli CFT073 1039806 NP_755617.1 CDS dkgA NC_004431.1 3578267 3579094 D methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 3578267..3579094 Escherichia coli CFT073 1039807 NP_755618.1 CDS yqhG NC_004431.1 3579568 3580221 D Escherichia coli K-12 ortholog: b3013; Escherichia coli O157:H7 ortholog: z4368; hypothetical protein 3579568..3580221 Escherichia coli CFT073 1039808 NP_755619.1 CDS yqhH NC_004431.1 3580272 3580529 D Escherichia coli K-12 ortholog: b3014; Escherichia coli O157:H7 ortholog: z4369; outer membrane lipoprotein 3580272..3580529 Escherichia coli CFT073 1039810 NP_755620.1 CDS c3749 NC_004431.1 3580571 3582790 R Escherichia coli O157:H7 ortholog: z4370; hypothetical protein complement(3580571..3582790) Escherichia coli CFT073 1039811 NP_755621.1 CDS c3750 NC_004431.1 3583042 3583791 D Residues 1 to 248 of 249 are 78.62 pct identical to residues 18 to 265 of 266 from GenPept.129 : >gb|AAL21959.1| (AE008842) regulatory protein, gntR family [Salmonella typhimurium LT2]; regulator 3583042..3583791 Escherichia coli CFT073 1039812 NP_755622.1 CDS c3751 NC_004431.1 3584078 3585586 D Escherichia coli K-12 ortholog: b1542; Escherichia coli O157:H7 ortholog: z2155; oxidoreductase ydfI 3584078..3585586 Escherichia coli CFT073 1039813 NP_755623.1 CDS c3752 NC_004431.1 3585583 3586599 D Escherichia coli K-12 ortholog: b4358; Escherichia coli O157:H7 ortholog: z5958; hypothetical protein 3585583..3586599 Escherichia coli CFT073 1039814 NP_755624.1 CDS c3753 NC_004431.1 3586610 3587620 D Escherichia coli K-12 ortholog: b0517; Escherichia coli O157:H7 ortholog: z0672; ureidoglycolate dehydrogenase 3586610..3587620 Escherichia coli CFT073 1039815 NP_755625.1 CDS c3754 NC_004431.1 3587693 3588676 D Residues 1 to 327 of 327 are 84.09 pct identical to residues 1 to 327 of 327 from GenPept.129 : >gb|AAL22043.1| (AE008845) dicarboxylate-binding periplasmic protein [Salmonella typhimurium LT2]; c4-dicarboxylate transport system binding protein 3587693..3588676 Escherichia coli CFT073 1039816 NP_755626.1 CDS c3755 NC_004431.1 3588718 3589200 D Residues 1 to 158 of 160 are 78.48 pct identical to residues 1 to 158 of 160 from GenPept.129 : >gb|AAL22044.1| (AE008845) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein 3588718..3589200 Escherichia coli CFT073 1039817 NP_755627.1 CDS ygiK NC_004431.1 3589169 3590515 D Residues 15 to 447 of 448 are 89.83 pct identical to residues 1 to 433 of 435 from SwissProt.40 : >sp|P40800|YGIK_SALTY Hypothetical 46.1 kDa protein in PLSC 3'region; c4-dicarboxylate permease 3589169..3590515 Escherichia coli CFT073 1039818 NP_755628.1 CDS sufI NC_004431.1 3590586 3591998 R Escherichia coli K-12 ortholog: b3017; Escherichia coli O157:H7 ortholog: z4371; repressor protein for FtsI complement(3590586..3591998) Escherichia coli CFT073 1039819 NP_755629.1 CDS plsC NC_004431.1 3592073 3592810 R Escherichia coli K-12 ortholog: b3018; Escherichia coli O157:H7 ortholog: z4372; 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(3592073..3592810) Escherichia coli CFT073 1039820 NP_755630.1 CDS c3759 NC_004431.1 3592859 3593014 R hypothetical protein complement(3592859..3593014) Escherichia coli CFT073 1039822 NP_755631.1 CDS parC NC_004431.1 3593045 3595303 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A complement(3593045..3595303) Escherichia coli CFT073 1039823 NP_755632.1 CDS c3761 NC_004431.1 3595441 3597111 R YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system; binding protein complement(3595441..3597111) Escherichia coli CFT073 1039876 NP_755633.1 CDS ygiV NC_004431.1 3597157 3597639 R Escherichia coli K-12 ortholog: b3023; Escherichia coli O157:H7 ortholog: z4375; hypothetical protein complement(3597157..3597639) Escherichia coli CFT073 1039900 NP_755634.1 CDS ygiW NC_004431.1 3597692 3598141 R Escherichia coli K-12 ortholog: b3024; Escherichia coli O157:H7 ortholog: z4376; hypothetical protein complement(3597692..3598141) Escherichia coli CFT073 1039901 NP_755635.1 CDS ygiX NC_004431.1 3598236 3598895 D response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 3598236..3598895 Escherichia coli CFT073 1039902 NP_755636.1 CDS ygiY NC_004431.1 3598892 3600241 D Escherichia coli K-12 ortholog: b3026; Escherichia coli O157:H7 ortholog: z4378; sensor protein QseC 3598892..3600241 Escherichia coli CFT073 1039904 NP_755637.1 CDS c3766 NC_004431.1 3600626 3601363 R hypothetical protein complement(3600626..3601363) Escherichia coli CFT073 1039905 NP_755638.1 CDS c3767 NC_004431.1 3601339 3601818 R Escherichia coli O157:H7 ortholog: z0248; hypothetical protein complement(3601339..3601818) Escherichia coli CFT073 1039906 NP_755639.1 CDS mdaB NC_004431.1 3602068 3602649 D Escherichia coli K-12 ortholog: b3028; Escherichia coli O157:H7 ortholog: z4379; modulator of drug activity B 3602068..3602649 Escherichia coli CFT073 1039908 NP_755640.1 CDS ygiN NC_004431.1 3602680 3602994 D Escherichia coli K-12 ortholog: b3029; Escherichia coli O157:H7 ortholog: z4380; hypothetical protein 3602680..3602994 Escherichia coli CFT073 1039909 NP_755641.1 CDS c3770 NC_004431.1 3603039 3603926 R Escherichia coli O157:H7 ortholog: z4381; hypothetical protein complement(3603039..3603926) Escherichia coli CFT073 1039910 NP_755642.1 CDS c3771 NC_004431.1 3603923 3604933 R Escherichia coli O157:H7 ortholog: z4382; iron ABC transporter substrate-binding protein complement(3603923..3604933) Escherichia coli CFT073 1039911 NP_755643.1 CDS c3772 NC_004431.1 3604881 3605930 R Escherichia coli O157:H7 ortholog: z4383; iron ABC transporter permease complement(3604881..3605930) Escherichia coli CFT073 1039912 NP_755644.1 CDS c3773 NC_004431.1 3605927 3606910 R Escherichia coli O157:H7 ortholog: z4384; iron ABC transporter permease complement(3605927..3606910) Escherichia coli CFT073 1039913 NP_755645.1 CDS c3774 NC_004431.1 3606907 3607716 R Escherichia coli K-12 ortholog: b0588; Escherichia coli O157:H7 ortholog: z4385; ferric enterobactin transport ATP-binding protein fepC complement(3606907..3607716) Escherichia coli CFT073 1039914 NP_755646.1 CDS c3775 NC_004431.1 3608090 3610231 D Escherichia coli O157:H7 ortholog: z4386; iron compound receptor 3608090..3610231 Escherichia coli CFT073 1039915 NP_755647.1 CDS parE NC_004431.1 3610295 3612187 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(3610295..3612187) Escherichia coli CFT073 1039916 NP_755648.1 CDS yqiA NC_004431.1 3612216 3612797 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase complement(3612216..3612797) Escherichia coli CFT073 1039917 NP_755649.1 CDS icc NC_004431.1 3612797 3613624 R Escherichia coli K-12 ortholog: b3032; Escherichia coli O157:H7 ortholog: z4389; cyclic 3',5'-adenosine monophosphate phosphodiesterase complement(3612797..3613624) Escherichia coli CFT073 1039918 NP_755650.1 CDS yqiB NC_004431.1 3613649 3614071 R Escherichia coli K-12 ortholog: b3033; Escherichia coli O157:H7 ortholog: z4390; hypothetical protein complement(3613649..3614071) Escherichia coli CFT073 1039919 NP_755651.1 CDS nudF NC_004431.1 3614072 3614701 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase complement(3614072..3614701) Escherichia coli CFT073 1039920 NP_755652.2 CDS tolC NC_004431.1 3614906 3616387 D trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 3614906..3616387 Escherichia coli CFT073 1039921 NP_755653.1 CDS ygiA NC_004431.1 3616387 3616647 D Escherichia coli K-12 ortholog: b3036; Escherichia coli O157:H7 ortholog: z4393; hypothetical protein 3616387..3616647 Escherichia coli CFT073 1039922 NP_755654.2 CDS ygiB NC_004431.1 3616535 3617206 D Escherichia coli K-12 ortholog: b3037; Escherichia coli O157:H7 ortholog: z4394; hypothetical protein 3616535..3617206 Escherichia coli CFT073 1039923 NP_755655.1 CDS ygiC NC_004431.1 3617212 3618372 D Escherichia coli K-12 ortholog: b3038; Escherichia coli O157:H7 ortholog: z4395; hypothetical protein 3617212..3618372 Escherichia coli CFT073 1039924 NP_755656.1 CDS asst NC_004431.1 3618857 3620653 D Residues 1 to 598 of 598 are 100.00 pct identical to residues 1 to 598 of 598 from GenPept.129 : >gb|AAB49808.1| (U32616) Klebsiella sp. arylsulfate sulfotransferase; arylsulfate sulfotransferase 3618857..3620653 Escherichia coli CFT073 1039925 NP_755657.1 CDS c3786 NC_004431.1 3620671 3621339 D Residues 1 to 222 of 222 are 100.00 pct identical to residues 1 to 222 of 222 from SwissProt.40 : >sp|P97037|DSBA_KLEPN Thiol:disulfide interchange protein dsbA precursor; disulfide isomerase 3620671..3621339 Escherichia coli CFT073 1039926 NP_755658.1 CDS c3787 NC_004431.1 3621354 3622025 D Residues 3 to 223 of 223 are 87.33 pct identical to residues 4 to 224 of 225 from GenPept.129 : >gb|AAL22068.1| (AE008846) disulfide isomerase [Salmonella typhimurium LT2]; disulfide oxidoreductase 3621354..3622025 Escherichia coli CFT073 1039927 NP_755659.1 CDS ygiD NC_004431.1 3622071 3622886 R seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein complement(3622071..3622886) Escherichia coli CFT073 1039928 NP_755660.1 CDS ygiE NC_004431.1 3622960 3623775 D Escherichia coli K-12 ortholog: b3040; Escherichia coli O157:H7 ortholog: z4397; zinc transporter ZupT 3622960..3623775 Escherichia coli CFT073 1039929 NP_755661.1 CDS c3790 NC_004431.1 3623837 3624022 R Escherichia coli O157:H7 ortholog: z4398; hypothetical protein complement(3623837..3624022) Escherichia coli CFT073 1039930 NP_755662.1 CDS ygiL NC_004431.1 3624578 3625141 D Escherichia coli K-12 ortholog: b3043; Escherichia coli O157:H7 ortholog: z0872; fimbrial protein 3624578..3625141 Escherichia coli CFT073 1039931 NP_755663.1 CDS yqiG NC_004431.1 3625228 3627750 D Escherichia coli K-12 ortholog: b3046; Escherichia coli O157:H7 ortholog: z0871; outer membrane usher protein yqiG 3625228..3627750 Escherichia coli CFT073 1039932 NP_755664.1 CDS yqiH NC_004431.1 3627757 3628506 D Escherichia coli K-12 ortholog: b3047; Escherichia coli O157:H7 ortholog: z0869; fimbrial chaperone yqiH 3627757..3628506 Escherichia coli CFT073 1039936 NP_755665.1 CDS c3794 NC_004431.1 3628503 3629552 D Residues 7 to 349 of 349 are 37.92 pct identical to residues 8 to 353 of 353 from GenPept.129 : >gb|AAG55039.1|AE005249_10 (AE005249) ybgO gene product [Escherichia coli O157:H7 EDL933]; hypothetical protein 3628503..3629552 Escherichia coli CFT073 1039938 NP_755666.1 CDS ribB NC_004431.1 3629606 3630259 R DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase complement(3629606..3630259) Escherichia coli CFT073 1039939 NP_755667.1 CDS yqiC NC_004431.1 3630573 3630932 D Escherichia coli K-12 ortholog: b3042; Escherichia coli O157:H7 ortholog: z4400; hypothetical protein 3630573..3630932 Escherichia coli CFT073 1039940 NP_755668.1 CDS glgS NC_004431.1 3630967 3631173 R Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS complement(3630967..3631173) Escherichia coli CFT073 1039942 NP_755669.1 CDS yqiJ NC_004431.1 3631437 3632066 D Escherichia coli K-12 ortholog: b3050; Escherichia coli O157:H7 ortholog: z4402; hypothetical protein 3631437..3632066 Escherichia coli CFT073 1039943 NP_755670.1 CDS yqiK NC_004431.1 3632093 3633754 D Escherichia coli K-12 ortholog: b3051; Escherichia coli O157:H7 ortholog: z4403; hypothetical protein 3632093..3633754 Escherichia coli CFT073 1039944 NP_755671.1 CDS c3800 NC_004431.1 3634173 3635606 R catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase complement(3634173..3635606) Escherichia coli CFT073 1039945 NP_755672.2 CDS glnE NC_004431.1 3635654 3638494 R catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase complement(3635654..3638494) Escherichia coli CFT073 1039946 NP_755673.1 CDS ygiF NC_004431.1 3638517 3639845 R ORFXE; Escherichia coli K-12 ortholog: b3054; Escherichia coli O157:H7 ortholog: z4407; hypothetical protein complement(3638517..3639845) Escherichia coli CFT073 1039947 NP_755674.1 CDS c3803 NC_004431.1 3639888 3640340 R Escherichia coli O157:H7 ortholog: z5815; transposase complement(3639888..3640340) Escherichia coli CFT073 1039948 NP_755675.1 CDS ydcM NC_004431.1 3640353 3641558 D Escherichia coli K-12 ortholog: b1432; Escherichia coli O157:H7 ortholog: z3664; hypothetical protein 3640353..3641558 Escherichia coli CFT073 1039951 NP_755676.1 CDS ygiM NC_004431.1 3641901 3642521 D Escherichia coli K-12 ortholog: b3055; Escherichia coli O157:H7 ortholog: z4408; signal transduction protein 3641901..3642521 Escherichia coli CFT073 1039952 NP_755677.1 CDS cca NC_004431.1 3642585 3643823 D catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 3642585..3643823 Escherichia coli CFT073 1039953 NP_755678.1 CDS uppP NC_004431.1 3643903 3644727 R BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase complement(3643903..3644727) Escherichia coli CFT073 1039954 NP_755679.1 CDS folB NC_004431.1 3644815 3645186 R catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase complement(3644815..3645186) Escherichia coli CFT073 1039956 NP_755680.1 CDS ygiH NC_004431.1 3645288 3645905 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 3645288..3645905 Escherichia coli CFT073 1039957 NP_755681.1 CDS ygiP NC_004431.1 3645918 3646898 R activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR complement(3645918..3646898) Escherichia coli CFT073 1039958 NP_755682.1 CDS c3811 NC_004431.1 3646881 3647003 D hypothetical protein 3646881..3647003 Escherichia coli CFT073 1039960 NP_755683.1 CDS ttdA NC_004431.1 3647057 3647968 D Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 3647057..3647968 Escherichia coli CFT073 1039961 NP_755684.1 CDS ttdB NC_004431.1 3647965 3648570 D Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 3647965..3648570 Escherichia coli CFT073 1039963 NP_755685.1 CDS ygjE NC_004431.1 3648618 3650081 D Escherichia coli K-12 ortholog: b3063; Escherichia coli O157:H7 ortholog: z4416; tartrate carrier/transporter 3648618..3650081 Escherichia coli CFT073 1039964 NP_755686.1 CDS ygjD NC_004431.1 3650124 3651137 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease complement(3650124..3651137) Escherichia coli CFT073 1039965 NP_755687.1 CDS rpsU NC_004431.1 3651375 3651590 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 3651375..3651590 Escherichia coli CFT073 1039967 NP_755688.1 CDS dnaG NC_004431.1 3651701 3653446 D synthesizes RNA primers at the replication forks; DNA primase 3651701..3653446 Escherichia coli CFT073 1039969 NP_755689.1 CDS c3818 NC_004431.1 3653460 3653582 D hypothetical protein 3653460..3653582 Escherichia coli CFT073 1039971 NP_755690.1 CDS c3819 NC_004431.1 3653641 3654747 D Residues 1 to 313 of 319 are 89.00 pct identical to residues 51 to 363 of 613 from MG1655 : b3067; hypothetical protein 3653641..3654747 Escherichia coli CFT073 1039973 NP_755691.1 CDS c3820 NC_004431.1 3654441 3655538 R hypothetical protein complement(3654441..3655538) Escherichia coli CFT073 1039974 NP_755692.1 CDS rpoD NC_004431.1 3654744 3655484 D Polymerase sigma factor; Residues 2 to 246 of 246 are 99.59 pct identical to residues 416 to 660 of 660 from GenPept.129 : >gb|AAL22085.1| (AE008847) sigma D (sigma 70) factor of RNA polymerase, major sigma factor during exponential growth [Salmonella typhimurium LT2]; RpoD protein 3654744..3655484 Escherichia coli CFT073 1039975 NP_755693.1 CDS ygjF NC_004431.1 3655562 3656068 R Escherichia coli K-12 ortholog: b3068; Escherichia coli O157:H7 ortholog: z4421; G/U mismatch-specific DNA glycosylase complement(3655562..3656068) Escherichia coli CFT073 1039976 NP_755694.1 CDS yqjH NC_004431.1 3656322 3657101 R Escherichia coli K-12 ortholog: b3070; Escherichia coli O157:H7 ortholog: z4423; hypothetical protein complement(3656322..3657101) Escherichia coli CFT073 1039979 NP_755695.1 CDS yqjI NC_004431.1 3657374 3657997 D Escherichia coli K-12 ortholog: b3071; Escherichia coli O157:H7 ortholog: z4424; hypothetical protein 3657374..3657997 Escherichia coli CFT073 1039981 NP_755696.1 CDS aer NC_004431.1 3658151 3659671 R Escherichia coli K-12 ortholog: b3072; Escherichia coli O157:H7 ortholog: z4425; aerotaxis receptor complement(3658151..3659671) Escherichia coli CFT073 1039983 NP_755697.1 CDS c3826 NC_004431.1 3659862 3659990 R hypothetical protein complement(3659862..3659990) Escherichia coli CFT073 1039984 NP_755698.1 CDS c3827 NC_004431.1 3659947 3660153 D hypothetical protein 3659947..3660153 Escherichia coli CFT073 1039985 NP_755699.2 CDS ygjG NC_004431.1 3660062 3661468 D catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 3660062..3661468 Escherichia coli CFT073 1039986 NP_755700.1 CDS c3829 NC_004431.1 3661452 3661862 D hypothetical protein 3661452..3661862 Escherichia coli CFT073 1039987 NP_755701.1 CDS ygjH NC_004431.1 3661510 3661842 R Escherichia coli K-12 ortholog: b3074; Escherichia coli O157:H7 ortholog: z4427; hypothetical protein complement(3661510..3661842) Escherichia coli CFT073 1039988 NP_755702.1 CDS c3831 NC_004431.1 3661949 3662131 D hypothetical protein 3661949..3662131 Escherichia coli CFT073 1039989 NP_755703.1 CDS ebgR NC_004431.1 3662061 3663044 D Escherichia coli K-12 ortholog: b3075; Escherichia coli O157:H7 ortholog: z4428; DNA-binding transcriptional repressor EbgR 3662061..3663044 Escherichia coli CFT073 1039992 NP_755704.2 CDS ebgA NC_004431.1 3663228 3666320 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 3663228..3666320 Escherichia coli CFT073 1039993 NP_755705.1 CDS ebgC NC_004431.1 3666317 3666766 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 3666317..3666766 Escherichia coli CFT073 1039995 NP_755706.1 CDS c3835 NC_004431.1 3666617 3666757 R hypothetical protein complement(3666617..3666757) Escherichia coli CFT073 1039996 NP_755707.1 CDS ygjI NC_004431.1 3666829 3668262 D Escherichia coli K-12 ortholog: b3078; Escherichia coli O157:H7 ortholog: z4431; transporter YgjI 3666829..3668262 Escherichia coli CFT073 1039997 NP_755708.1 CDS ygjJ NC_004431.1 3668396 3669466 D Escherichia coli K-12 ortholog: b3079; Escherichia coli O157:H7 ortholog: z4432; hypothetical protein 3668396..3669466 Escherichia coli CFT073 1040000 NP_755709.1 CDS ygjK NC_004431.1 3669483 3671834 D Escherichia coli K-12 ortholog: b3080; Escherichia coli O157:H7 ortholog: z4433; glycosyl hydrolase 3669483..3671834 Escherichia coli CFT073 1040001 NP_755710.1 CDS ygjL NC_004431.1 3672060 3674078 D NADPH; Escherichia coli K-12 ortholog: b3081; Escherichia coli O157:H7 ortholog: z4434; 2,4-dienoyl-CoA reductase 3672060..3674078 Escherichia coli CFT073 1040002 NP_755711.1 CDS c3840 NC_004431.1 3674123 3674539 R Escherichia coli K-12 ortholog: b3082; Escherichia coli O157:H7 ortholog: z4435; hypothetical protein complement(3674123..3674539) Escherichia coli CFT073 1040003 NP_755712.1 CDS c3841 NC_004431.1 3674536 3674706 R Residues 32 to 56 of 56 are 100.00 pct identical to residues 80 to 104 of 104 from GenPept.129 : >gb|AAG58216.1|AE005538_3 (AE005538) orf, hypothetical protein [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(3674536..3674706) Escherichia coli CFT073 1040004 NP_755713.1 CDS ygjO NC_004431.1 3674810 3675946 R Escherichia coli K-12 ortholog: b3084; Escherichia coli O157:H7 ortholog: z4437; ribosomal RNA small subunit methyltransferase D complement(3674810..3675946) Escherichia coli CFT073 1040005 NP_755714.1 CDS ygjP NC_004431.1 3675995 3676534 D Escherichia coli K-12 ortholog: b3085; Escherichia coli O157:H7 ortholog: z4438; hypothetical protein 3675995..3676534 Escherichia coli CFT073 1040008 NP_755715.1 CDS ygjQ NC_004431.1 3676602 3677303 D Escherichia coli K-12 ortholog: b3086; Escherichia coli O157:H7 ortholog: z4439; hypothetical protein 3676602..3677303 Escherichia coli CFT073 1040009 NP_755716.1 CDS ygjR NC_004431.1 3677364 3678368 D Escherichia coli K-12 ortholog: b3087; Escherichia coli O157:H7 ortholog: z4440; oxidoreductase ygjR 3677364..3678368 Escherichia coli CFT073 1040010 NP_755717.1 CDS ygjT NC_004431.1 3678652 3679617 D Escherichia coli K-12 ortholog: b3088; Escherichia coli O157:H7 ortholog: z4441; hypothetical protein 3678652..3679617 Escherichia coli CFT073 1040011 NP_755718.1 CDS ygjU NC_004431.1 3679941 3681185 D involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 3679941..3681185 Escherichia coli CFT073 1040012 NP_755719.1 CDS ygjV NC_004431.1 3681189 3681740 R Escherichia coli K-12 ortholog: b3090; Escherichia coli O157:H7 ortholog: z4443; hypothetical protein complement(3681189..3681740) Escherichia coli CFT073 1040014 NP_755720.1 CDS uxaA NC_004431.1 3681823 3683310 R Escherichia coli K-12 ortholog: b3091; Escherichia coli O157:H7 ortholog: z4444; altronate hydrolase complement(3681823..3683310) Escherichia coli CFT073 1040015 NP_755721.2 CDS uxaC NC_004431.1 3683325 3684737 R catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase complement(3683325..3684737) Escherichia coli CFT073 1040016 NP_755722.1 CDS exuT NC_004431.1 3685100 3686518 D Escherichia coli K-12 ortholog: b3093; Escherichia coli O157:H7 ortholog: z4446; hexuronate transporter 3685100..3686518 Escherichia coli CFT073 1040017 NP_755723.2 CDS exuR NC_004431.1 3686648 3687424 D regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 3686648..3687424 Escherichia coli CFT073 1040018 NP_755724.1 CDS yqjA NC_004431.1 3687769 3688431 D Escherichia coli K-12 ortholog: b3095; Escherichia coli O157:H7 ortholog: z4449; hypothetical protein 3687769..3688431 Escherichia coli CFT073 1040019 NP_755725.1 CDS yqjB NC_004431.1 3688435 3688818 D Escherichia coli K-12 ortholog: b3096; Escherichia coli O157:H7 ortholog: z4450; hypothetical protein 3688435..3688818 Escherichia coli CFT073 1040041 NP_755726.3 CDS yqjC NC_004431.1 3688950 3689333 D Escherichia coli K-12 ortholog: b3097; Escherichia coli O157:H7 ortholog: z4451; hypothetical protein 3688950..3689333 Escherichia coli CFT073 1040047 NP_755727.1 CDS yqjD NC_004431.1 3689371 3689676 D Escherichia coli K-12 ortholog: b3098; Escherichia coli O157:H7 ortholog: z4452; hypothetical protein 3689371..3689676 Escherichia coli CFT073 1040049 NP_755728.1 CDS yqjE NC_004431.1 3689679 3690083 D Escherichia coli K-12 ortholog: b3099; Escherichia coli O157:H7 ortholog: z4453; hypothetical protein 3689679..3690083 Escherichia coli CFT073 1040059 NP_755729.1 CDS yqjK NC_004431.1 3690073 3690372 D Escherichia coli K-12 ortholog: b3100; Escherichia coli O157:H7 ortholog: z4454; hypothetical protein 3690073..3690372 Escherichia coli CFT073 1040061 NP_755730.1 CDS yqjF NC_004431.1 3690546 3690950 D Escherichia coli K-12 ortholog: b3101; Escherichia coli O157:H7 ortholog: z4455; hypothetical protein 3690546..3690950 Escherichia coli CFT073 1040067 NP_755731.1 CDS yhaH NC_004431.1 3692270 3692659 D Escherichia coli K-12 ortholog: b3103; Escherichia coli O157:H7 ortholog: z4457; hypothetical protein 3692270..3692659 Escherichia coli CFT073 1040077 NP_755732.1 CDS yhaJ NC_004431.1 3692693 3693589 R Escherichia coli K-12 ortholog: b3105; Escherichia coli O157:H7 ortholog: z4459; transcriptional regulator YhaJ complement(3692693..3693589) Escherichia coli CFT073 1040078 NP_755733.1 CDS yhaK NC_004431.1 3693694 3694395 D Escherichia coli K-12 ortholog: b3106; Escherichia coli O157:H7 ortholog: z4460; hypothetical protein 3693694..3694395 Escherichia coli CFT073 1040080 NP_755734.1 CDS c3865 NC_004431.1 3694153 3694281 R hypothetical protein complement(3694153..3694281) Escherichia coli CFT073 1040082 NP_755735.1 CDS yhaL NC_004431.1 3694412 3694582 D Escherichia coli K-12 ortholog: b3107; Escherichia coli O157:H7 ortholog: z4461; hypothetical protein 3694412..3694582 Escherichia coli CFT073 1040084 NP_755736.1 CDS c3867 NC_004431.1 3694716 3696026 R Escherichia coli O157:H7 ortholog: z4462; hypothetical protein complement(3694716..3696026) Escherichia coli CFT073 1040085 NP_755737.1 CDS c3870 NC_004431.1 3697665 3699035 R Escherichia coli K-12 ortholog: b1814; Escherichia coli O157:H7 ortholog: z4464; L-serine dehydratase 1 complement(3697665..3699035) Escherichia coli CFT073 1040095 NP_755738.1 CDS yhaR NC_004431.1 3699101 3699553 R Escherichia coli K-12 ortholog: b3113; Escherichia coli O157:H7 ortholog: z4465; hypothetical protein complement(3699101..3699553) Escherichia coli CFT073 1040096 NP_755739.1 CDS tdcE NC_004431.1 3699504 3701798 R Escherichia coli K-12 ortholog: b3114; Escherichia coli O157:H7 ortholog: z4466; keto-acid formate acetyltransferase complement(3699504..3701798) Escherichia coli CFT073 1040101 NP_755740.1 CDS c3873 NC_004431.1 3701832 3701984 R Residues 1 to 50 of 50 are 98.00 pct identical to residues 357 to 406 of 406 from MG1655 : b3115; hypothetical protein complement(3701832..3701984) Escherichia coli CFT073 1040103 NP_755741.1 CDS tdcC NC_004431.1 3703066 3704397 R involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC complement(3703066..3704397) Escherichia coli CFT073 1040107 NP_755742.1 CDS tdcB NC_004431.1 3704419 3705408 R catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase complement(3704419..3705408) Escherichia coli CFT073 1040111 NP_755743.1 CDS tdcA NC_004431.1 3705507 3706445 R regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA complement(3705507..3706445) Escherichia coli CFT073 1040114 NP_755744.3 CDS tdcR NC_004431.1 3706622 3706978 D participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 3706622..3706978 Escherichia coli CFT073 1040115 NP_755745.1 CDS c3878 NC_004431.1 3707204 3707332 D Residues 4 to 41 of 42 are 87.80 pct identical to residues 1 to 41 of 186 from GenPept.129 : >emb|CAC50646.1| (AX188965) unnamed protein product [Escherichia coli]; hypothetical protein 3707204..3707332 Escherichia coli CFT073 1040120 NP_755746.2 CDS yhaD NC_004431.1 3707944 3709089 R Escherichia coli K-12 ortholog: b3124; Escherichia coli O157:H7 ortholog: z4476; glycerate kinase I complement(3707944..3709089) Escherichia coli CFT073 1040121 NP_755747.2 CDS garR NC_004431.1 3709186 3710076 R catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase complement(3709186..3710076) Escherichia coli CFT073 1040122 NP_755748.1 CDS yhaF NC_004431.1 3710106 3710876 R cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase complement(3710106..3710876) Escherichia coli CFT073 1040124 NP_755749.1 CDS yhaU NC_004431.1 3710892 3712226 R D-galactarate permease; Escherichia coli K-12 ortholog: b3127; Escherichia coli O157:H7 ortholog: z4479; galactarate transporter complement(3710892..3712226) Escherichia coli CFT073 1040127 NP_755750.1 CDS yhaG NC_004431.1 3712601 3714172 D Escherichia coli K-12 ortholog: b3128; Escherichia coli O157:H7 ortholog: z4480; D-galactarate dehydratase 3712601..3714172 Escherichia coli CFT073 1040129 NP_755751.1 CDS sohA NC_004431.1 3714321 3714656 D SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation; regulator PrlF 3714321..3714656 Escherichia coli CFT073 1040131 NP_755752.1 CDS yhaV NC_004431.1 3714656 3715120 D Escherichia coli K-12 ortholog: b3130; Escherichia coli O157:H7 ortholog: z4482; hypothetical protein 3714656..3715120 Escherichia coli CFT073 1040132 NP_755753.1 CDS agaR NC_004431.1 3715175 3715984 R transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR complement(3715175..3715984) Escherichia coli CFT073 1040133 NP_755754.1 CDS agaZ NC_004431.1 3716233 3717513 D Escherichia coli K-12 ortholog: b3132; Escherichia coli O157:H7 ortholog: z4484; tagatose 6-phosphate kinase agaZ 3716233..3717513 Escherichia coli CFT073 1040135 NP_755755.1 CDS agaV NC_004431.1 3717500 3718009 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3717500..3718009 Escherichia coli CFT073 1040137 NP_755756.1 CDS c3889 NC_004431.1 3718020 3718799 D Escherichia coli O157:H7 ortholog: z4486; phosphotransferase system enzyme subunit 3718020..3718799 Escherichia coli CFT073 1040144 NP_755757.1 CDS c3890 NC_004431.1 3718783 3719667 D EIID-AGA; Escherichia coli K-12 ortholog: b3140; Escherichia coli O157:H7 ortholog: z4487; PTS system, N-acetylgalactosamine-specific IID component 3718783..3719667 Escherichia coli CFT073 1040146 NP_755758.1 CDS c3891 NC_004431.1 3719685 3720119 D Escherichia coli O157:H7 ortholog: z4488; phosphotransferase system enzyme subunit 3719685..3720119 Escherichia coli CFT073 1040148 NP_755759.1 CDS c3892 NC_004431.1 3720095 3721249 D Escherichia coli O157:H7 ortholog: z4489; N-acetylgalctosamine-6-phosphate deacetylase 3720095..3721249 Escherichia coli CFT073 1040150 NP_755760.1 CDS agaS NC_004431.1 3721598 3722752 D Escherichia coli K-12 ortholog: b3136; Escherichia coli O157:H7 ortholog: z4490; tagatose-6-phosphate ketose/aldose isomerase 3721598..3722752 Escherichia coli CFT073 1040157 NP_755761.1 CDS kbaY NC_004431.1 3722765 3723625 D catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3722765..3723625 Escherichia coli CFT073 1040161 NP_755762.1 CDS agaB NC_004431.1 3723792 3724268 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3723792..3724268 Escherichia coli CFT073 1040162 NP_755763.1 CDS agaC NC_004431.1 3724307 3725110 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIC 3724307..3725110 Escherichia coli CFT073 1040163 NP_755764.1 CDS agaD NC_004431.1 3725031 3725891 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID 3725031..3725891 Escherichia coli CFT073 1040165 NP_755765.1 CDS agaI NC_004431.1 3725892 3726659 D Escherichia coli K-12 ortholog: b3141; Escherichia coli O157:H7 ortholog: z4497; galactosamine-6-phosphate isomerase 3725892..3726659 Escherichia coli CFT073 1040167 NP_755766.1 CDS yraL NC_004431.1 3726709 3727572 R Escherichia coli K-12 ortholog: b3146; Escherichia coli O157:H7 ortholog: z4505; hypothetical protein complement(3726709..3727572) Escherichia coli CFT073 1040168 NP_755767.1 CDS yraM NC_004431.1 3727512 3729674 D Escherichia coli K-12 ortholog: b3147; Escherichia coli O157:H7 ortholog: z4506; hypothetical protein 3727512..3729674 Escherichia coli CFT073 1040171 NP_755768.1 CDS yraN NC_004431.1 3729632 3730027 D Escherichia coli K-12 ortholog: b3148; Escherichia coli O157:H7 ortholog: z4507; hypothetical protein 3729632..3730027 Escherichia coli CFT073 1040172 NP_755769.1 CDS c3902 NC_004431.1 3729896 3730021 R hypothetical protein complement(3729896..3730021) Escherichia coli CFT073 1040173 NP_755770.1 CDS yraO NC_004431.1 3730047 3730637 D Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 3730047..3730637 Escherichia coli CFT073 1040174 NP_755771.1 CDS yraP NC_004431.1 3730647 3731222 D Escherichia coli K-12 ortholog: b3150; Escherichia coli O157:H7 ortholog: z4509; hypothetical protein 3730647..3731222 Escherichia coli CFT073 1040176 NP_755772.1 CDS yraQ NC_004431.1 3731335 3732375 R Escherichia coli K-12 ortholog: b3151; Escherichia coli O157:H7 ortholog: z4510; hypothetical protein complement(3731335..3732375) Escherichia coli CFT073 1040177 NP_755773.1 CDS yraR NC_004431.1 3732448 3733083 R Escherichia coli K-12 ortholog: b3152; Escherichia coli O157:H7 ortholog: z4511; hypothetical protein complement(3732448..3733083) Escherichia coli CFT073 1040179 NP_755774.1 CDS yhbP NC_004431.1 3733125 3733547 R Escherichia coli K-12 ortholog: b3154; Escherichia coli O157:H7 ortholog: z4514; hypothetical protein complement(3733125..3733547) Escherichia coli CFT073 1040180 NP_755775.1 CDS yhbQ NC_004431.1 3733598 3733900 D Escherichia coli K-12 ortholog: b3155; Escherichia coli O157:H7 ortholog: z4516; GIY-YIG nuclease superfamily protein 3733598..3733900 Escherichia coli CFT073 1040182 NP_755776.1 CDS yhbS NC_004431.1 3733887 3734390 R Escherichia coli K-12 ortholog: b3156; Escherichia coli O157:H7 ortholog: z4517; acetyltransferase YhbS complement(3733887..3734390) Escherichia coli CFT073 1040184 NP_755777.1 CDS yhbT NC_004431.1 3734384 3734932 R Escherichia coli K-12 ortholog: b3157; Escherichia coli O157:H7 ortholog: z4518; hypothetical protein complement(3734384..3734932) Escherichia coli CFT073 1040187 NP_755778.1 CDS yhbU NC_004431.1 3735090 3736112 D Escherichia coli K-12 ortholog: b3158; Escherichia coli O157:H7 ortholog: z4519; protease yhbU 3735090..3736112 Escherichia coli CFT073 1040193 NP_755779.1 CDS yhbV NC_004431.1 3736103 3736999 D Escherichia coli K-12 ortholog: b3159; Escherichia coli O157:H7 ortholog: z4520; hypothetical protein 3736103..3736999 Escherichia coli CFT073 1040195 NP_755780.1 CDS yhbW NC_004431.1 3737080 3738087 D Escherichia coli K-12 ortholog: b3160; Escherichia coli O157:H7 ortholog: z4521; hypothetical protein 3737080..3738087 Escherichia coli CFT073 1040204 NP_755781.1 CDS mtr NC_004431.1 3738206 3739450 R tryptophan transporter of high affinity; tryptophan permease complement(3738206..3739450) Escherichia coli CFT073 1040206 NP_755782.1 CDS c3915 NC_004431.1 3739466 3739603 D hypothetical protein 3739466..3739603 Escherichia coli CFT073 1040209 NP_755783.2 CDS deaD NC_004431.1 3739604 3741493 R participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD complement(3739604..3741493) Escherichia coli CFT073 1040245 NP_755784.1 CDS c3917 NC_004431.1 3741630 3741788 D hypothetical protein 3741630..3741788 Escherichia coli CFT073 1040248 NP_755785.1 CDS yhbM NC_004431.1 3741673 3742557 R lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI complement(3741673..3742557) Escherichia coli CFT073 1040250 NP_755786.1 CDS c3919 NC_004431.1 3742603 3744825 D hypothetical protein 3742603..3744825 Escherichia coli CFT073 1040251 NP_755787.1 CDS pnp NC_004431.1 3742666 3744888 R Escherichia coli K-12 ortholog: b3164; Escherichia coli O157:H7 ortholog: z4525; polynucleotide phosphorylase complement(3742666..3744888) Escherichia coli CFT073 1040255 NP_755788.1 CDS rpsO NC_004431.1 3745048 3745317 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(3745048..3745317) Escherichia coli CFT073 1040257 NP_755789.1 CDS truB NC_004431.1 3745466 3746410 R catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(3745466..3746410) Escherichia coli CFT073 1040258 NP_755790.2 CDS rbfA NC_004431.1 3746410 3746811 R associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A complement(3746410..3746811) Escherichia coli CFT073 1040259 NP_755791.1 CDS infB NC_004431.1 3746975 3749647 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(3746975..3749647) Escherichia coli CFT073 1040260 NP_755792.1 CDS c3925 NC_004431.1 3749504 3750973 D hypothetical protein 3749504..3750973 Escherichia coli CFT073 1040261 NP_755793.1 CDS nusA NC_004431.1 3749672 3751159 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(3749672..3751159) Escherichia coli CFT073 1040263 NP_755794.2 CDS yhbC NC_004431.1 3751187 3751639 R in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein complement(3751187..3751639) Escherichia coli CFT073 1040264 YP_004853821.1 CDS c3928 NC_004431.1 3751822 3752184 D hypothetical protein 3751822..3752184 Escherichia coli CFT073 1040266 NP_755796.1 CDS argG NC_004431.1 3752270 3753613 D catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 3752270..3753613 Escherichia coli CFT073 1040269 NP_755797.1 CDS yhbX NC_004431.1 3753621 3755279 R Escherichia coli K-12 ortholog: b3173; Escherichia coli O157:H7 ortholog: z4535; outer-membrane protein yhbX complement(3753621..3755279) Escherichia coli CFT073 1040270 NP_755798.2 CDS secG NC_004431.1 3755804 3756136 R Preprotein translocase band 1 subunit; Escherichia coli K-12 ortholog: b3175; Escherichia coli O157:H7 ortholog: z4537; preprotein translocase subunit SecG complement(3755804..3756136) Escherichia coli CFT073 1040273 NP_755799.1 CDS glmM NC_004431.1 3756364 3757701 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(3756364..3757701) Escherichia coli CFT073 1040274 NP_755800.2 CDS folP NC_004431.1 3757694 3758542 R catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase complement(3757694..3758542) Escherichia coli CFT073 1040275 NP_755801.1 CDS c3935 NC_004431.1 3760536 3760670 D hypothetical protein 3760536..3760670 Escherichia coli CFT073 1040277 NP_755802.1 CDS rrmJ NC_004431.1 3760667 3761296 R Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase complement(3760667..3761296) Escherichia coli CFT073 1040278 NP_755803.1 CDS yhbY NC_004431.1 3761422 3761715 D RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 3761422..3761715 Escherichia coli CFT073 1040279 NP_755804.1 CDS greA NC_004431.1 3761871 3762347 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(3761871..3762347) Escherichia coli CFT073 1040284 NP_755805.1 CDS dacB NC_004431.1 3762596 3764029 D penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase/endopeptidase 3762596..3764029 Escherichia coli CFT073 1040285 NP_755806.1 CDS obgE NC_004431.1 3764070 3765242 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(3764070..3765242) Escherichia coli CFT073 1040289 NP_755807.1 CDS yhbE NC_004431.1 3765258 3766223 R Escherichia coli K-12 ortholog: b3184; Escherichia coli O157:H7 ortholog: z4546; transport protein YhbE complement(3765258..3766223) Escherichia coli CFT073 1040290 NP_755808.1 CDS rpmA NC_004431.1 3766350 3766607 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(3766350..3766607) Escherichia coli CFT073 1040292 NP_755809.1 CDS c3943 NC_004431.1 3766437 3766562 D hypothetical protein 3766437..3766562 Escherichia coli CFT073 1040293 NP_755810.1 CDS c3944 NC_004431.1 3766601 3767146 D hypothetical protein 3766601..3767146 Escherichia coli CFT073 1040295 NP_755811.1 CDS ispB NC_004431.1 3767198 3768169 D Escherichia coli K-12 ortholog: b3187; Escherichia coli O157:H7 ortholog: z4550; octaprenyl diphosphate synthase 3767198..3768169 Escherichia coli CFT073 1040301 NP_755812.1 CDS nlp NC_004431.1 3768402 3768680 D activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 3768402..3768680 Escherichia coli CFT073 1040303 NP_755813.1 CDS murA NC_004431.1 3768728 3769987 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(3768728..3769987) Escherichia coli CFT073 1040304 NP_755814.1 CDS yrbA NC_004431.1 3770042 3770311 R Escherichia coli K-12 ortholog: b3190; Escherichia coli O157:H7 ortholog: z4553; hypothetical protein complement(3770042..3770311) Escherichia coli CFT073 1040305 NP_755815.1 CDS c3949 NC_004431.1 3770108 3770449 D hypothetical protein 3770108..3770449 Escherichia coli CFT073 1040307 NP_755816.1 CDS yrbB NC_004431.1 3770456 3770845 R Escherichia coli K-12 ortholog: b3191; Escherichia coli O157:H7 ortholog: z4554; hypothetical protein complement(3770456..3770845) Escherichia coli CFT073 1040308 NP_755817.1 CDS c3951 NC_004431.1 3770737 3771372 D hypothetical protein 3770737..3771372 Escherichia coli CFT073 1040309 NP_755818.1 CDS yrbC NC_004431.1 3770749 3771384 R Escherichia coli K-12 ortholog: b3192; Escherichia coli O157:H7 ortholog: z4555; hypothetical protein complement(3770749..3771384) Escherichia coli CFT073 1040310 NP_755819.1 CDS yrbD NC_004431.1 3771403 3771969 R Escherichia coli K-12 ortholog: b3193; Escherichia coli O157:H7 ortholog: z4556; hypothetical protein complement(3771403..3771969) Escherichia coli CFT073 1040311 NP_755820.1 CDS yrbE NC_004431.1 3771959 3772741 R Escherichia coli K-12 ortholog: b3194; Escherichia coli O157:H7 ortholog: z4557; hypothetical protein complement(3771959..3772741) Escherichia coli CFT073 1040312 NP_755821.1 CDS yrbF NC_004431.1 3772749 3773558 R ATP-binding subunit of a ABC toluene efflux transporter; ABC transporter ATP-binding protein YrbF complement(3772749..3773558) Escherichia coli CFT073 1040316 NP_755822.1 CDS yrbG NC_004431.1 3773768 3774745 D YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; calcium/sodium:proton antiporter 3773768..3774745 Escherichia coli CFT073 1040317 NP_755823.1 CDS c3957 NC_004431.1 3774738 3775745 D Escherichia coli K-12 ortholog: b3197; Escherichia coli O157:H7 ortholog: z4560; D-arabinose 5-phosphate isomerase 3774738..3775745 Escherichia coli CFT073 1040318 NP_755824.1 CDS yrbI NC_004431.1 3775766 3776332 D forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 3775766..3776332 Escherichia coli CFT073 1040319 NP_755825.1 CDS yrbK NC_004431.1 3776329 3776904 D Escherichia coli K-12 ortholog: b3199; Escherichia coli O157:H7 ortholog: z4562; hypothetical protein 3776329..3776904 Escherichia coli CFT073 1040320 NP_755826.1 CDS yhbN NC_004431.1 3776852 3777430 D LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 3776852..3777430 Escherichia coli CFT073 1040323 NP_755827.1 CDS yhbG NC_004431.1 3777437 3778162 D Escherichia coli K-12 ortholog: b3201; Escherichia coli O157:H7 ortholog: z4564; ABC transporter ATP-binding protein YhbG 3777437..3778162 Escherichia coli CFT073 1040324 NP_755828.1 CDS rpoN NC_004431.1 3778210 3779643 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 3778210..3779643 Escherichia coli CFT073 1040326 NP_755829.1 CDS yhbH NC_004431.1 3779666 3779953 D YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; sigma(54) modulation protein 3779666..3779953 Escherichia coli CFT073 1040328 NP_755830.1 CDS ptsN NC_004431.1 3780047 3780562 D Escherichia coli K-12 ortholog: b3204; Escherichia coli O157:H7 ortholog: z4567; PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 3780047..3780562 Escherichia coli CFT073 1040329 NP_755831.1 CDS yhbJ NC_004431.1 3780608 3781462 D Escherichia coli K-12 ortholog: b3205; Escherichia coli O157:H7 ortholog: z4568; hypothetical protein 3780608..3781462 Escherichia coli CFT073 1040332 NP_755832.1 CDS ptsO NC_004431.1 3781459 3781731 D Nitrogen related HPr; Escherichia coli K-12 ortholog: b3206; Escherichia coli O157:H7 ortholog: z4569; phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 3781459..3781731 Escherichia coli CFT073 1040333 NP_755833.1 CDS yrbL NC_004431.1 3781944 3782576 D Escherichia coli K-12 ortholog: b3207; Escherichia coli O157:H7 ortholog: z4570; hypothetical protein 3781944..3782576 Escherichia coli CFT073 1040335 NP_755834.1 CDS mtgA NC_004431.1 3782573 3783301 R glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase complement(3782573..3783301) Escherichia coli CFT073 1040336 NP_755835.1 CDS yhbL NC_004431.1 3783298 3783951 R Sigma cross-reacting protein 27A; Escherichia coli K-12 ortholog: b3209; Escherichia coli O157:H7 ortholog: z4573; isoprenoid biosynthesis protein with amidotransferase-like domain complement(3783298..3783951) Escherichia coli CFT073 1040338 NP_755836.1 CDS arcB NC_004431.1 3784181 3786517 R sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB complement(3784181..3786517) Escherichia coli CFT073 1040339 NP_755837.1 CDS yhcC NC_004431.1 3786613 3787479 R Escherichia coli K-12 ortholog: b3211; Escherichia coli O157:H7 ortholog: z4575; hypothetical protein complement(3786613..3787479) Escherichia coli CFT073 1040340 NP_755838.1 CDS c3972 NC_004431.1 3787807 3787944 R hypothetical protein complement(3787807..3787944) Escherichia coli CFT073 1040341 NP_755839.2 CDS gltB NC_004431.1 3788124 3792677 D catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 3788124..3792677 Escherichia coli CFT073 1040342 NP_755840.1 CDS gltD NC_004431.1 3792690 3794108 D glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3792690..3794108 Escherichia coli CFT073 1040344 NP_755841.1 CDS yhcH NC_004431.1 3794176 3794640 R Escherichia coli K-12 ortholog: b3221; Escherichia coli O157:H7 ortholog: z4579; hypothetical protein complement(3794176..3794640) Escherichia coli CFT073 1040345 NP_755842.2 CDS c3976 NC_004431.1 3794637 3795512 R catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase complement(3794637..3795512) Escherichia coli CFT073 1040347 NP_755843.1 CDS yhcJ NC_004431.1 3795509 3796240 R Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase complement(3795509..3796240) Escherichia coli CFT073 1040348 NP_755844.2 CDS nanT NC_004431.1 3796246 3797736 R Escherichia coli K-12 ortholog: b3224; Escherichia coli O157:H7 ortholog: z4582; sialic acid transporter complement(3796246..3797736) Escherichia coli CFT073 1040349 NP_755845.1 CDS nanA NC_004431.1 3797845 3798738 R catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase complement(3797845..3798738) Escherichia coli CFT073 1040350 NP_755846.1 CDS yhcK NC_004431.1 3798860 3799651 R Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR complement(3798860..3799651) Escherichia coli CFT073 1040351 NP_755847.1 CDS sspB NC_004431.1 3799759 3800256 R Escherichia coli K-12 ortholog: b3228; Escherichia coli O157:H7 ortholog: z4586; ClpXP protease specificity-enhancing factor complement(3799759..3800256) Escherichia coli CFT073 1040352 NP_755848.1 CDS sspA NC_004431.1 3800262 3800900 R transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A complement(3800262..3800900) Escherichia coli CFT073 1040353 NP_755849.1 CDS c3983 NC_004431.1 3800842 3801051 D hypothetical protein 3800842..3801051 Escherichia coli CFT073 1040354 NP_755850.1 CDS rpsI NC_004431.1 3801295 3801687 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(3801295..3801687) Escherichia coli CFT073 1040355 NP_755851.2 CDS rplM NC_004431.1 3801703 3802131 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(3801703..3802131) Escherichia coli CFT073 1040357 NP_755852.1 CDS yhcM NC_004431.1 3802351 3803478 R Escherichia coli K-12 ortholog: b3232; Escherichia coli O157:H7 ortholog: z4591; hypothetical protein complement(3802351..3803478) Escherichia coli CFT073 1040358 NP_755853.1 CDS yhcB NC_004431.1 3803666 3804070 D Escherichia coli K-12 ortholog: b3233; Escherichia coli O157:H7 ortholog: z4592; cytochrome d ubiquinol oxidase subunit III 3803666..3804070 Escherichia coli CFT073 1040360 NP_755854.1 CDS c3988 NC_004431.1 3803718 3804131 D hypothetical protein 3803718..3804131 Escherichia coli CFT073 1040362 NP_755855.1 CDS degQ NC_004431.1 3804182 3805591 D Escherichia coli K-12 ortholog: b3234; Escherichia coli O157:H7 ortholog: z4593; serine endoprotease 3804182..3805591 Escherichia coli CFT073 1040363 NP_755856.1 CDS degS NC_004431.1 3805681 3806748 D Escherichia coli K-12 ortholog: b3235; Escherichia coli O157:H7 ortholog: z4594; serine endoprotease 3805681..3806748 Escherichia coli CFT073 1040366 NP_755857.2 CDS mdh NC_004431.1 3806811 3807749 R oxidizes malate to oxaloacetate; malate dehydrogenase complement(3806811..3807749) Escherichia coli CFT073 1040367 NP_755858.1 CDS argR NC_004431.1 3808184 3808654 D regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor ArgR 3808184..3808654 Escherichia coli CFT073 1040368 NP_755859.1 CDS yhcN NC_004431.1 3808967 3809281 D Escherichia coli K-12 ortholog: b3238; Escherichia coli O157:H7 ortholog: z4597; hypothetical protein 3808967..3809281 Escherichia coli CFT073 1040370 NP_755860.1 CDS yhcO NC_004431.1 3809336 3809608 R Escherichia coli K-12 ortholog: b3239; Escherichia coli O157:H7 ortholog: z4598; hypothetical protein complement(3809336..3809608) Escherichia coli CFT073 1040371 NP_755861.1 CDS yhcP NC_004431.1 3809700 3811667 R with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB complement(3809700..3811667) Escherichia coli CFT073 1040372 NP_755862.1 CDS yhcQ NC_004431.1 3811673 3812605 R with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA complement(3811673..3812605) Escherichia coli CFT073 1040374 NP_755863.2 CDS yhcR NC_004431.1 3812613 3812816 R membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein complement(3812613..3812816) Escherichia coli CFT073 1040375 NP_755864.1 CDS yhcS NC_004431.1 3812999 3813928 D Escherichia coli K-12 ortholog: b3243; Escherichia coli O157:H7 ortholog: z4602; DNA-binding transcriptional regulator 3812999..3813928 Escherichia coli CFT073 1040376 NP_755865.1 CDS tldD NC_004431.1 3814056 3815501 R responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD complement(3814056..3815501) Escherichia coli CFT073 1040379 NP_755866.1 CDS yhdP NC_004431.1 3815657 3819457 R Escherichia coli K-12 ortholog: b3245; Escherichia coli O157:H7 ortholog: z4604; hypothetical protein complement(3815657..3819457) Escherichia coli CFT073 1040382 NP_755867.2 CDS cafA NC_004431.1 3819525 3820994 R involved in the processing of the 5'end of 16S rRNA; ribonuclease G complement(3819525..3820994) Escherichia coli CFT073 1040383 NP_755868.1 CDS maf NC_004431.1 3820984 3821577 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(3820984..3821577) Escherichia coli CFT073 1040384 NP_755869.1 CDS mreD NC_004431.1 3821586 3822074 R part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD complement(3821586..3822074) Escherichia coli CFT073 1040385 YP_004853822.1 CDS c4004 NC_004431.1 3822058 3822189 R hypothetical protein complement(3822058..3822189) Escherichia coli CFT073 1040386 NP_755871.1 CDS mreC NC_004431.1 3822074 3823177 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(3822074..3823177) Escherichia coli CFT073 1040387 NP_755872.2 CDS mreB NC_004431.1 3823243 3824286 R functions in MreBCD complex in some organisms; rod shape-determining protein MreB complement(3823243..3824286) Escherichia coli CFT073 1040388 NP_755873.1 CDS c4007 NC_004431.1 3824394 3824582 D hypothetical protein 3824394..3824582 Escherichia coli CFT073 1040389 NP_755874.1 CDS yhdA NC_004431.1 3824591 3826531 R regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD complement(3824591..3826531) Escherichia coli CFT073 1040390 NP_755875.1 CDS yhdH NC_004431.1 3826683 3827657 D Escherichia coli K-12 ortholog: b3253; Escherichia coli O157:H7 ortholog: z4612; hypothetical protein 3826683..3827657 Escherichia coli CFT073 1040391 NP_755876.1 CDS c4010 NC_004431.1 3827694 3827858 D hypothetical protein 3827694..3827858 Escherichia coli CFT073 1040392 NP_755877.1 CDS accB NC_004431.1 3828635 3829105 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3828635..3829105 Escherichia coli CFT073 1040393 NP_755878.2 CDS accC NC_004431.1 3829116 3830465 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 3829116..3830465 Escherichia coli CFT073 1040394 NP_755879.1 CDS c4013 NC_004431.1 3830557 3831603 R Residues 10 to 332 of 348 are 34.70 pct identical to residues 18 to 355 of 355 from GenPept.129 : >emb|CAB55728.1| (AL117387) hypothetical protein SCF41.25 [Streptomyces coelicolor A3(2)]; hypothetical protein complement(3830557..3831603) Escherichia coli CFT073 1040395 NP_755880.1 CDS c4014 NC_004431.1 3831600 3832562 R Residues 4 to 312 of 320 are 54.98 pct identical to residues 5 to 315 of 315 from GenPept.129 : >gb|AAL22123.1| (AE008850) sugar kinase, ribokinase family [Salmonella typhimurium LT2]; hypothetical protein complement(3831600..3832562) Escherichia coli CFT073 1040397 NP_755881.1 CDS c4015 NC_004431.1 3832584 3833573 R Escherichia coli K-12 ortholog: b3750; Escherichia coli O157:H7 ortholog: z5690; ribose ABC transporter permease complement(3832584..3833573) Escherichia coli CFT073 1040398 NP_755882.1 CDS c4016 NC_004431.1 3833574 3835100 R Escherichia coli K-12 ortholog: b3749; Escherichia coli O157:H7 ortholog: z5250; ribose ABC transporter ATP-binding protein complement(3833574..3835100) Escherichia coli CFT073 1040399 NP_755883.1 CDS c4017 NC_004431.1 3835131 3836027 R Ribose-binding protein; Residues 5 to 298 of 298 are 60.67 pct identical to residues 2 to 296 of 296 from GenPept.129 : >emb|CAC49355.1| (AL603645) sugar uptake ABC transporter periplasmic solute-binding protein precursor [Sinorhizobium meliloti]; ribose ABC transporter complement(3835131..3836027) Escherichia coli CFT073 1040401 NP_755884.1 CDS gatY NC_004431.1 3836057 3836911 R catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase complement(3836057..3836911) Escherichia coli CFT073 1040402 NP_755885.1 CDS c4019 NC_004431.1 3836886 3837014 D hypothetical protein 3836886..3837014 Escherichia coli CFT073 1040404 NP_755886.1 CDS c4020 NC_004431.1 3837253 3838083 D Residues 8 to 270 of 276 are 42.00 pct identical to residues 3 to 270 of 277 from GenPept.129 : >gb|AAL22124.1| (AE008850) aga operon transcriptional repressor (DeoR family) [Salmonella typhimurium LT2]; hypothetical protein 3837253..3838083 Escherichia coli CFT073 1040407 NP_755887.1 CDS c4021 NC_004431.1 3838040 3839050 D Residues 22 to 335 of 336 are 56.68 pct identical to residues 4 to 313 of 315 from GenPept.129 : >gb|AAL22123.1| (AE008850) sugar kinase, ribokinase family [Salmonella typhimurium LT2]; hypothetical protein 3838040..3839050 Escherichia coli CFT073 1040408 NP_755888.1 CDS yhdT NC_004431.1 3839125 3839385 D Escherichia coli K-12 ortholog: b3257; Escherichia coli O157:H7 ortholog: z4617; hypothetical protein 3839125..3839385 Escherichia coli CFT073 1040412 NP_755889.2 CDS panF NC_004431.1 3839375 3840826 D mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 3839375..3840826 Escherichia coli CFT073 1040421 NP_755890.1 CDS prmA NC_004431.1 3840838 3841719 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 3840838..3841719 Escherichia coli CFT073 1040428 NP_755891.1 CDS c4025 NC_004431.1 3841700 3841828 R hypothetical protein complement(3841700..3841828) Escherichia coli CFT073 1040429 NP_755892.1 CDS yhdG NC_004431.1 3842048 3843013 D Escherichia coli K-12 ortholog: b3260; Escherichia coli O157:H7 ortholog: z4620; tRNA-dihydrouridine synthase B 3842048..3843013 Escherichia coli CFT073 1040433 NP_755893.1 CDS fis NC_004431.1 3843039 3843335 D Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 3843039..3843335 Escherichia coli CFT073 1040434 NP_755894.2 CDS yhdJ NC_004431.1 3843421 3844305 D Escherichia coli K-12 ortholog: b3262; Escherichia coli O157:H7 ortholog: z4622; methyltransferase 3843421..3844305 Escherichia coli CFT073 1040437 NP_755895.1 CDS yhdU NC_004431.1 3844362 3844568 D Escherichia coli K-12 ortholog: b3263; Escherichia coli O157:H7 ortholog: z4623; hypothetical protein 3844362..3844568 Escherichia coli CFT073 1040438 NP_755896.1 CDS envR NC_004431.1 3844571 3845233 R Escherichia coli K-12 ortholog: b3264; Escherichia coli O157:H7 ortholog: z4624; DNA-binding transcriptional regulator EnvR complement(3844571..3845233) Escherichia coli CFT073 1040440 NP_755897.1 CDS acrE NC_004431.1 3845632 3846789 D Protein envC; Escherichia coli K-12 ortholog: b3265; Escherichia coli O157:H7 ortholog: z4625; acriflavin resistance protein E 3845632..3846789 Escherichia coli CFT073 1040443 NP_755898.1 CDS acrF NC_004431.1 3846801 3849905 D Protein envD; Escherichia coli K-12 ortholog: b3266; Escherichia coli O157:H7 ortholog: z0576; acriflavin resistance protein F 3846801..3849905 Escherichia coli CFT073 1040446 NP_755899.1 CDS yhdV NC_004431.1 3850158 3850379 D Escherichia coli K-12 ortholog: b3267; Escherichia coli O157:H7 ortholog: z4628; hypothetical protein 3850158..3850379 Escherichia coli CFT073 1040448 NP_755900.1 CDS yhdW NC_004431.1 3850810 3851835 D Escherichia coli K-12 ortholog: b3268; Escherichia coli O157:H7 ortholog: z4629; amino-acid ABC transporter binding protein yhdW 3850810..3851835 Escherichia coli CFT073 1040449 NP_755901.1 CDS yhdX NC_004431.1 3851885 3853084 D Escherichia coli K-12 ortholog: b3269; Escherichia coli O157:H7 ortholog: z4630; amino-acid ABC transporter permease YhdX 3851885..3853084 Escherichia coli CFT073 1040451 NP_755902.1 CDS yhdY NC_004431.1 3853091 3854197 D Escherichia coli K-12 ortholog: b3270; Escherichia coli O157:H7 ortholog: z4631; amino-acid ABC transporter permease YhdY 3853091..3854197 Escherichia coli CFT073 1040453 NP_755903.1 CDS yhdZ NC_004431.1 3854205 3854963 D Escherichia coli K-12 ortholog: b3271; Escherichia coli O157:H7 ortholog: z4632; amino-acid ABC transporter ATP-binding protein YhdZ 3854205..3854963 Escherichia coli CFT073 1040458 NP_755904.1 CDS yrdA NC_004431.1 3860309 3861157 D Escherichia coli K-12 ortholog: b3279; Escherichia coli O157:H7 ortholog: z4650; hypothetical protein 3860309..3861157 Escherichia coli CFT073 1040481 NP_755905.1 CDS yrdB NC_004431.1 3861133 3861390 R Escherichia coli K-12 ortholog: b3280; Escherichia coli O157:H7 ortholog: z4651; hypothetical protein complement(3861133..3861390) Escherichia coli CFT073 1040482 NP_755906.1 CDS aroE NC_004431.1 3861387 3862205 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(3861387..3862205) Escherichia coli CFT073 1040483 NP_755907.1 CDS yrdC NC_004431.1 3862210 3862827 R RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; ribosome maturation factor complement(3862210..3862827) Escherichia coli CFT073 1040484 NP_755908.1 CDS yrdD NC_004431.1 3862787 3863329 R Escherichia coli K-12 ortholog: b3283; Escherichia coli O157:H7 ortholog: z4654; hypothetical protein complement(3862787..3863329) Escherichia coli CFT073 1040485 NP_755909.1 CDS smg NC_004431.1 3863358 3863831 R Escherichia coli K-12 ortholog: b3284; Escherichia coli O157:H7 ortholog: z4655; hypothetical protein complement(3863358..3863831) Escherichia coli CFT073 1040486 NP_755910.1 CDS smf NC_004431.1 3863803 3864927 R Escherichia coli K-12 ortholog: b3286; Escherichia coli O157:H7 ortholog: z4656; DNA protecting protein DprA complement(3863803..3864927) Escherichia coli CFT073 1040488 NP_755911.1 CDS def NC_004431.1 3865057 3865566 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 3865057..3865566 Escherichia coli CFT073 1040490 NP_755912.1 CDS fmt NC_004431.1 3865581 3866528 D modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 3865581..3866528 Escherichia coli CFT073 1040491 NP_755913.1 CDS sun NC_004431.1 3866580 3867869 D catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase GidB 3866580..3867869 Escherichia coli CFT073 1040492 NP_755914.1 CDS trkA NC_004431.1 3867891 3869267 D involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 3867891..3869267 Escherichia coli CFT073 1040493 NP_755915.1 CDS mscL NC_004431.1 3869397 3869810 D forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3869397..3869810 Escherichia coli CFT073 1040496 NP_755916.1 CDS yhdL NC_004431.1 3869807 3870025 R Residues 1 to 72 of 72 are 98.61 pct identical to residues 1 to 72 of 72 from SwissProt.40 : >sp|P36675|YHDL_ECOLI Hypothetical protein yhdL; regulator complement(3869807..3870025) Escherichia coli CFT073 1040500 NP_755917.1 CDS zntR NC_004431.1 3870081 3870506 R mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator complement(3870081..3870506) Escherichia coli CFT073 1040501 NP_755918.1 CDS yhdN NC_004431.1 3870517 3870885 R Escherichia coli K-12 ortholog: b3293; Escherichia coli O157:H7 ortholog: z4663; hypothetical protein complement(3870517..3870885) Escherichia coli CFT073 1040502 NP_755919.1 CDS rplQ NC_004431.1 3870992 3871375 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(3870992..3871375) Escherichia coli CFT073 1040503 NP_755920.1 CDS rpoA NC_004431.1 3871416 3872405 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(3871416..3872405) Escherichia coli CFT073 1040504 NP_755921.1 CDS rpsD NC_004431.1 3872431 3873051 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(3872431..3873051) Escherichia coli CFT073 1040505 NP_755922.1 CDS rpsK NC_004431.1 3873085 3873474 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(3873085..3873474) Escherichia coli CFT073 1040506 YP_004853823.1 CDS c4059 NC_004431.1 3873121 3873501 D hypothetical protein 3873121..3873501 Escherichia coli CFT073 1040511 NP_755924.1 CDS rpsM NC_004431.1 3873491 3873847 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(3873491..3873847) Escherichia coli CFT073 1034925 NP_755925.1 CDS secY NC_004431.1 3874142 3875473 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(3874142..3875473) Escherichia coli CFT073 1035715 NP_755926.1 CDS rplO NC_004431.1 3875481 3875915 R late assembly protein; 50S ribosomal protein L15 complement(3875481..3875915) Escherichia coli CFT073 1035704 NP_755927.1 CDS rpmD NC_004431.1 3875919 3876098 R L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 complement(3875919..3876098) Escherichia coli CFT073 1035652 NP_755928.1 CDS c4064 NC_004431.1 3876072 3876623 D hypothetical protein 3876072..3876623 Escherichia coli CFT073 1035734 NP_755929.1 CDS rpsE NC_004431.1 3876102 3876605 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(3876102..3876605) Escherichia coli CFT073 1035718 NP_755930.1 CDS rplR NC_004431.1 3876620 3876973 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(3876620..3876973) Escherichia coli CFT073 1035677 NP_755931.1 CDS c4067 NC_004431.1 3876674 3877297 D hypothetical protein 3876674..3877297 Escherichia coli CFT073 1035810 NP_755932.1 CDS rplF NC_004431.1 3876983 3877516 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(3876983..3877516) Escherichia coli CFT073 1035767 NP_755933.1 CDS c4069 NC_004431.1 3877382 3877939 D hypothetical protein 3877382..3877939 Escherichia coli CFT073 1035726 NP_755934.1 CDS rpsH NC_004431.1 3877529 3877921 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(3877529..3877921) Escherichia coli CFT073 1035709 NP_755935.1 CDS rpsN NC_004431.1 3877955 3878260 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(3877955..3878260) Escherichia coli CFT073 1035842 NP_755936.1 CDS rplE NC_004431.1 3878275 3878814 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(3878275..3878814) Escherichia coli CFT073 1035728 NP_755937.1 CDS rplX NC_004431.1 3878829 3879143 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(3878829..3879143) Escherichia coli CFT073 1035787 NP_755938.1 CDS c4074 NC_004431.1 3879025 3879579 D hypothetical protein 3879025..3879579 Escherichia coli CFT073 1035711 NP_755939.1 CDS rplN NC_004431.1 3879154 3879525 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(3879154..3879525) Escherichia coli CFT073 1035870 NP_755940.1 CDS rpsQ NC_004431.1 3879690 3879944 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(3879690..3879944) Escherichia coli CFT073 1035830 NP_755941.1 CDS rpmC NC_004431.1 3879944 3880135 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(3879944..3880135) Escherichia coli CFT073 1037580 YP_004853824.1 CDS c4078 NC_004431.1 3880126 3880542 D hypothetical protein 3880126..3880542 Escherichia coli CFT073 1035789 NP_755943.1 CDS rplP NC_004431.1 3880135 3880545 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(3880135..3880545) Escherichia coli CFT073 1040508 NP_755944.1 CDS rpsC NC_004431.1 3880558 3881259 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(3880558..3881259) Escherichia coli CFT073 1039824 YP_004853825.1 CDS c4081 NC_004431.1 3881259 3881666 D hypothetical protein 3881259..3881666 Escherichia coli CFT073 1035976 NP_755946.1 CDS rplV NC_004431.1 3881277 3881609 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(3881277..3881609) Escherichia coli CFT073 1036587 NP_755947.1 CDS rpsS NC_004431.1 3881624 3881902 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(3881624..3881902) Escherichia coli CFT073 1035959 NP_755948.1 CDS c4084 NC_004431.1 3881886 3882812 D hypothetical protein 3881886..3882812 Escherichia coli CFT073 1039809 NP_755949.1 CDS rplB NC_004431.1 3881919 3882740 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(3881919..3882740) Escherichia coli CFT073 1036324 NP_755950.1 CDS c4086 NC_004431.1 3882740 3883321 D hypothetical protein 3882740..3883321 Escherichia coli CFT073 1035940 NP_755951.1 CDS rplW NC_004431.1 3882758 3883060 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(3882758..3883060) Escherichia coli CFT073 1036387 YP_004853826.1 CDS c4088 NC_004431.1 3883021 3883656 D hypothetical protein 3883021..3883656 Escherichia coli CFT073 1037945 NP_755953.1 CDS rplD NC_004431.1 3883057 3883662 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(3883057..3883662) Escherichia coli CFT073 1036029 NP_755954.1 CDS c4090 NC_004431.1 3883592 3884293 D hypothetical protein 3883592..3884293 Escherichia coli CFT073 1037454 NP_755955.1 CDS rplC NC_004431.1 3883673 3884302 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(3883673..3884302) Escherichia coli CFT073 1036019 NP_755956.1 CDS rpsJ NC_004431.1 3884335 3884646 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(3884335..3884646) Escherichia coli CFT073 1039718 NP_755957.1 CDS pinO NC_004431.1 3884884 3885306 R calcium-binding protein that may be required for the initiation of chromosome replication; chromosome replication protein PioO complement(3884884..3885306) Escherichia coli CFT073 1037588 NP_755958.1 CDS yheD NC_004431.1 3885308 3886777 R Escherichia coli K-12 ortholog: b3323; general secretion pathway protein A complement(3885308..3886777) Escherichia coli CFT073 1036057 NP_755959.1 CDS yheE NC_004431.1 3886957 3887772 D Escherichia coli K-12 ortholog: b3324; general secretion pathway protein C 3886957..3887772 Escherichia coli CFT073 1040036 NP_755960.1 CDS yheF NC_004431.1 3887744 3889708 D Escherichia coli K-12 ortholog: b3325; general secretion pathway protein D 3887744..3889708 Escherichia coli CFT073 1036074 NP_755961.1 CDS yheG NC_004431.1 3889718 3891199 D Type II traffic warden ATPase; Escherichia coli K-12 ortholog: b3326; Escherichia coli O157:H7 ortholog: z0117; general secretion pathway protein E 3889718..3891199 Escherichia coli CFT073 1036594 NP_755962.1 CDS hofF NC_004431.1 3891196 3892392 D Protein transport protein hofF; Escherichia coli K-12 ortholog: b3327; general secretion pathway protein F 3891196..3892392 Escherichia coli CFT073 1037565 NP_755963.1 CDS hofG NC_004431.1 3892402 3892839 D Protein transport protein hofG; Escherichia coli K-12 ortholog: b3328; general secretion pathway protein G 3892402..3892839 Escherichia coli CFT073 1036091 NP_755964.1 CDS hofH NC_004431.1 3892847 3893356 D Protein transport protein hofH; Escherichia coli K-12 ortholog: b3329; general secretion pathway protein H 3892847..3893356 Escherichia coli CFT073 1040247 NP_755965.1 CDS yheH NC_004431.1 3893314 3893730 D Escherichia coli K-12 ortholog: b3330; Escherichia coli O157:H7 ortholog: z5741; general secretion pathway protein I 3893314..3893730 Escherichia coli CFT073 1040286 NP_755966.1 CDS yheI NC_004431.1 3893723 3894310 D Escherichia coli K-12 ortholog: b3331; general secretion pathway protein J 3893723..3894310 Escherichia coli CFT073 1036100 NP_755967.1 CDS yheJ NC_004431.1 3894303 3895208 D Escherichia coli K-12 ortholog: b3332; general secretion pathway protein K 3894303..3895208 Escherichia coli CFT073 1037578 NP_755968.1 CDS yheK NC_004431.1 3895298 3896464 D Escherichia coli K-12 ortholog: b3333; Escherichia coli O157:H7 ortholog: z2633; general secretion pathway protein L 3895298..3896464 Escherichia coli CFT073 1036132 NP_755969.1 CDS pshM NC_004431.1 3896437 3896922 D Transport protein pshM; Escherichia coli K-12 ortholog: b3334; general secretion pathway protein M 3896437..3896922 Escherichia coli CFT073 1040299 NP_755970.1 CDS hofD NC_004431.1 3896922 3897599 D Escherichia coli K-12 ortholog: b3335; Escherichia coli O157:H7 ortholog: z4693; bifunctional; leader peptidase 3896922..3897599 Escherichia coli CFT073 1036161 NP_755971.1 CDS bfr NC_004431.1 3897628 3898104 R iron storage protein; bacterioferritin complement(3897628..3898104) Escherichia coli CFT073 1036151 NP_755972.1 CDS yheA NC_004431.1 3898176 3898370 R Escherichia coli K-12 ortholog: b3337; Escherichia coli O157:H7 ortholog: z4696; bacterioferritin-associated ferredoxin complement(3898176..3898370) Escherichia coli CFT073 1039588 NP_755973.1 CDS chiA NC_004431.1 3898539 3901241 R has endochitinase/lysozyme activity; normally extracellular but does not appear to be secreted by wild-type Escherichia coli under standard laboratory conditions by the type II secretion pathway ; expression is controlled by H-NS; secreted endochitinase complement(3898539..3901241) Escherichia coli CFT073 1036186 NP_755974.1 CDS c4110 NC_004431.1 3901326 3901484 R hypothetical protein complement(3901326..3901484) Escherichia coli CFT073 1040064 NP_755975.2 CDS tuf NC_004431.1 3901533 3902717 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(3901533..3902717) Escherichia coli CFT073 1036191 NP_755976.1 CDS fusA NC_004431.1 3902788 3904902 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(3902788..3904902) Escherichia coli CFT073 1040244 NP_755977.1 CDS c4113 NC_004431.1 3904978 3905412 D Residues 8 to 142 of 144 are 42.96 pct identical to residues 55 to 189 of 197 from GenPept.129 : >gb|AAF63989.1| (AF214675) unknown in vivo-induced protein 131-19 [Pseudomonas aeruginosa]; hypothetical protein 3904978..3905412 Escherichia coli CFT073 1036224 NP_755978.1 CDS rpsG NC_004431.1 3904999 3905469 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(3904999..3905469) Escherichia coli CFT073 1036212 YP_004853827.1 CDS c4115 NC_004431.1 3905482 3905943 D hypothetical protein 3905482..3905943 Escherichia coli CFT073 1040239 NP_755980.2 CDS rpsL NC_004431.1 3905566 3905940 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(3905566..3905940) Escherichia coli CFT073 1036280 NP_755981.1 CDS yheL NC_004431.1 3906066 3906353 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB complement(3906066..3906353) Escherichia coli CFT073 1040051 NP_755982.1 CDS yheM NC_004431.1 3906361 3906720 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC complement(3906361..3906720) Escherichia coli CFT073 1036287 NP_755983.1 CDS yheN NC_004431.1 3906720 3907106 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD complement(3906720..3907106) Escherichia coli CFT073 1036284 NP_755984.1 CDS yheO NC_004431.1 3907106 3907840 R Escherichia coli K-12 ortholog: b3346; Escherichia coli O157:H7 ortholog: z4704; hypothetical protein complement(3907106..3907840) Escherichia coli CFT073 1036314 NP_755985.1 CDS fkpA NC_004431.1 3907995 3908807 R rotamase; FKBP-type peptidylprolyl isomerase complement(3907995..3908807) Escherichia coli CFT073 1036405 NP_755986.1 CDS slyX NC_004431.1 3909028 3909246 D Escherichia coli K-12 ortholog: b3348; Escherichia coli O157:H7 ortholog: z4706; hypothetical protein 3909028..3909246 Escherichia coli CFT073 1036578 NP_755987.1 CDS slyD NC_004431.1 3909295 3909885 R rotamase; FKBP-type peptidylprolyl isomerase complement(3909295..3909885) Escherichia coli CFT073 1036353 NP_755988.1 CDS c4124 NC_004431.1 3909980 3910180 R Escherichia coli O157:H7 ortholog: z4708; hypothetical protein complement(3909980..3910180) Escherichia coli CFT073 1036326 NP_755989.1 CDS kefB NC_004431.1 3910190 3911995 R involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB complement(3910190..3911995) Escherichia coli CFT073 1036618 NP_755990.1 CDS yheR NC_004431.1 3911995 3912549 R required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG complement(3911995..3912549) Escherichia coli CFT073 1036379 NP_755991.1 CDS yheS NC_004431.1 3912677 3914590 D Escherichia coli K-12 ortholog: b3352; Escherichia coli O157:H7 ortholog: z4713; ABC transporter ATP-binding protein 3912677..3914590 Escherichia coli CFT073 1036362 NP_755992.1 CDS yheT NC_004431.1 3914590 3915612 D Escherichia coli K-12 ortholog: b3353; Escherichia coli O157:H7 ortholog: z4714; hydrolase 3914590..3915612 Escherichia coli CFT073 1035646 NP_755993.1 CDS yheU NC_004431.1 3915606 3915824 D Escherichia coli K-12 ortholog: b3354; Escherichia coli O157:H7 ortholog: z4715; hypothetical protein 3915606..3915824 Escherichia coli CFT073 1036671 NP_755994.1 CDS prkB NC_004431.1 3915878 3916747 D Escherichia coli K-12 ortholog: b3355; Escherichia coli O157:H7 ortholog: z4716; phosphoribulokinase 3915878..3916747 Escherichia coli CFT073 1036463 NP_755995.1 CDS yhfA NC_004431.1 3916802 3917206 R Escherichia coli K-12 ortholog: b3356; Escherichia coli O157:H7 ortholog: z4717; hypothetical protein complement(3916802..3917206) Escherichia coli CFT073 1036450 NP_755996.1 CDS crp NC_004431.1 3917508 3918140 D complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 3917508..3918140 Escherichia coli CFT073 1036667 NP_755997.1 CDS yhfK NC_004431.1 3918179 3920281 D Escherichia coli K-12 ortholog: b3358; Escherichia coli O157:H7 ortholog: z4719; hypothetical protein 3918179..3920281 Escherichia coli CFT073 1035992 NP_755998.1 CDS argD NC_004431.1 3920348 3921568 R DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein complement(3920348..3921568) Escherichia coli CFT073 1038036 NP_755999.1 CDS pabA NC_004431.1 3921654 3922217 R aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II complement(3921654..3922217) Escherichia coli CFT073 1036658 NP_756000.1 CDS fic NC_004431.1 3922249 3922851 R Escherichia coli K-12 ortholog: b3361; Escherichia coli O157:H7 ortholog: z4722; cell filamentation protein Fic complement(3922249..3922851) Escherichia coli CFT073 1036690 NP_756001.1 CDS yhfG NC_004431.1 3922841 3923008 R Escherichia coli K-12 ortholog: b3362; Escherichia coli O157:H7 ortholog: z4723; hypothetical protein complement(3922841..3923008) Escherichia coli CFT073 1036670 NP_756002.1 CDS ppiA NC_004431.1 3923113 3923685 R Escherichia coli K-12 ortholog: b3363; Escherichia coli O157:H7 ortholog: z4724; peptidyl-prolyl cis-trans isomerase A (rotamase A) complement(3923113..3923685) Escherichia coli CFT073 1036663 NP_756003.1 CDS yhfC NC_004431.1 3923956 3925137 D Escherichia coli K-12 ortholog: b3364; Escherichia coli O157:H7 ortholog: z4725; hypothetical protein 3923956..3925137 Escherichia coli CFT073 1036682 NP_756004.1 CDS c4140 NC_004431.1 3925270 3925446 R hypothetical protein complement(3925270..3925446) Escherichia coli CFT073 1038044 NP_756005.1 CDS nirB NC_004431.1 3925399 3927942 D Escherichia coli K-12 ortholog: b3365; Escherichia coli O157:H7 ortholog: z4726; nitrite reductase [NAD(P)H] large subunit 3925399..3927942 Escherichia coli CFT073 1036672 NP_756006.1 CDS nirD NC_004431.1 3927939 3928265 D involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 3927939..3928265 Escherichia coli CFT073 1036687 NP_756007.1 CDS nirC NC_004431.1 3928391 3929197 D member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 3928391..3929197 Escherichia coli CFT073 1036675 NP_756008.1 CDS cysG NC_004431.1 3929216 3930589 D multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 3929216..3930589 Escherichia coli CFT073 1036683 NP_756009.1 CDS yhfL NC_004431.1 3930841 3931008 D Escherichia coli K-12 ortholog: b3369; Escherichia coli O157:H7 ortholog: z4730; hypothetical protein 3930841..3931008 Escherichia coli CFT073 1036676 NP_756010.1 CDS yhfS NC_004431.1 3931116 3932201 R Escherichia coli K-12 ortholog: b3376; hypothetical protein complement(3931116..3932201) Escherichia coli CFT073 1036708 NP_756011.1 CDS yhfT NC_004431.1 3932213 3933517 R Escherichia coli K-12 ortholog: b3377; hypothetical protein complement(3932213..3933517) Escherichia coli CFT073 1036673 NP_756012.1 CDS yhfU NC_004431.1 3933529 3933921 R Escherichia coli K-12 ortholog: b3378; hypothetical protein complement(3933529..3933921) Escherichia coli CFT073 1036684 NP_756013.1 CDS yhfV NC_004431.1 3933893 3934771 R phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE); hydrolase complement(3933893..3934771) Escherichia coli CFT073 1036715 NP_756014.1 CDS yhfW NC_004431.1 3934768 3935994 R catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; mutase complement(3934768..3935994) Escherichia coli CFT073 1036701 NP_756015.1 CDS yhfX NC_004431.1 3935995 3937158 R Escherichia coli K-12 ortholog: b3381; hypothetical protein complement(3935995..3937158) Escherichia coli CFT073 1036711 NP_756016.1 CDS yhfY NC_004431.1 3937242 3937646 R Escherichia coli K-12 ortholog: b3382; hypothetical protein complement(3937242..3937646) Escherichia coli CFT073 1036697 NP_756017.1 CDS yhfZ NC_004431.1 3937621 3938469 R Escherichia coli K-12 ortholog: b3383; hypothetical protein complement(3937621..3938469) Escherichia coli CFT073 1036692 NP_756018.1 CDS trpS NC_004431.1 3938687 3939691 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(3938687..3939691) Escherichia coli CFT073 1036689 NP_756019.1 CDS gph NC_004431.1 3939684 3940442 R catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase complement(3939684..3940442) Escherichia coli CFT073 1036709 NP_756020.1 CDS rpe NC_004431.1 3940435 3941112 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(3940435..3941112) Escherichia coli CFT073 1036696 NP_756021.1 CDS dam NC_004431.1 3941130 3941966 R Escherichia coli K-12 ortholog: b3387; Escherichia coli O157:H7 ortholog: z4740; DNA adenine methylase complement(3941130..3941966) Escherichia coli CFT073 1036686 NP_756022.1 CDS damX NC_004431.1 3942073 3943359 R Escherichia coli K-12 ortholog: b3388; Escherichia coli O157:H7 ortholog: z4741; hypothetical protein complement(3942073..3943359) Escherichia coli CFT073 1036700 NP_756023.1 CDS aroB NC_004431.1 3943451 3944539 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(3943451..3944539) Escherichia coli CFT073 1036716 NP_756024.2 CDS aroK NC_004431.1 3944596 3945117 R type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I complement(3944596..3945117) Escherichia coli CFT073 1036725 NP_756025.1 CDS hofQ NC_004431.1 3945518 3946756 R outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ complement(3945518..3946756) Escherichia coli CFT073 1036707 NP_756026.1 CDS yrfA NC_004431.1 3946668 3947111 R Escherichia coli K-12 ortholog: b3392; Escherichia coli O157:H7 ortholog: z4746; hypothetical protein complement(3946668..3947111) Escherichia coli CFT073 1036733 NP_756027.1 CDS yrfB NC_004431.1 3947062 3947502 R Escherichia coli K-12 ortholog: b3393; Escherichia coli O157:H7 ortholog: z4747; hypothetical protein complement(3947062..3947502) Escherichia coli CFT073 1036729 NP_756028.1 CDS yrfC NC_004431.1 3947486 3948025 R Escherichia coli K-12 ortholog: b3394; Escherichia coli O157:H7 ortholog: z4748; hypothetical protein complement(3947486..3948025) Escherichia coli CFT073 1036719 NP_756029.1 CDS yrfD NC_004431.1 3948025 3948831 R Escherichia coli K-12 ortholog: b3395; Escherichia coli O157:H7 ortholog: z4749; hypothetical protein complement(3948025..3948831) Escherichia coli CFT073 1036712 NP_756030.2 CDS mrcA NC_004431.1 3948924 3951476 D bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 3948924..3951476 Escherichia coli CFT073 1036736 NP_756031.1 CDS nudE NC_004431.1 3951642 3952202 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE complement(3951642..3952202) Escherichia coli CFT073 1036737 NP_756032.1 CDS c4168 NC_004431.1 3952403 3952525 D hypothetical protein 3952403..3952525 Escherichia coli CFT073 1036742 NP_756033.1 CDS yrfF NC_004431.1 3952522 3954657 D Escherichia coli K-12 ortholog: b3398; Escherichia coli O157:H7 ortholog: z4752; membrane protein igaA-like protein 3952522..3954657 Escherichia coli CFT073 1036743 NP_756034.1 CDS yrfG NC_004431.1 3954677 3955390 D Escherichia coli K-12 ortholog: b3399; Escherichia coli O157:H7 ortholog: z4753; hypothetical protein 3954677..3955390 Escherichia coli CFT073 1036730 NP_756035.1 CDS yrfH NC_004431.1 3955401 3955802 D HSP15; Escherichia coli K-12 ortholog: b3400; Escherichia coli O157:H7 ortholog: z4754; ribosome-associated heat shock protein Hsp15 3955401..3955802 Escherichia coli CFT073 1036720 NP_756036.2 CDS hslO NC_004431.1 3955827 3956705 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 3955827..3956705 Escherichia coli CFT073 1036731 NP_756037.1 CDS yhgE NC_004431.1 3956843 3958567 R Escherichia coli K-12 ortholog: b3402; Escherichia coli O157:H7 ortholog: z4756; hypothetical protein complement(3956843..3958567) Escherichia coli CFT073 1036726 NP_756038.1 CDS c4174 NC_004431.1 3958573 3958701 R hypothetical protein complement(3958573..3958701) Escherichia coli CFT073 1036789 NP_756039.1 CDS c4175 NC_004431.1 3958643 3958774 R Escherichia coli O157:H7 ortholog: z4757; hypothetical protein complement(3958643..3958774) Escherichia coli CFT073 1036738 NP_756040.1 CDS pckA NC_004431.1 3958877 3960568 D PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 3958877..3960568 Escherichia coli CFT073 1036732 NP_756041.1 CDS c4177 NC_004431.1 3960691 3960870 D hypothetical protein 3960691..3960870 Escherichia coli CFT073 1036788 NP_756042.1 CDS c4178 NC_004431.1 3960843 3960995 D hypothetical protein 3960843..3960995 Escherichia coli CFT073 1036746 NP_756043.1 CDS c4179 NC_004431.1 3961054 3961350 D Escherichia coli K-12 ortholog: b3555; Escherichia coli O157:H7 ortholog: z4980; hypothetical protein 3961054..3961350 Escherichia coli CFT073 1036739 NP_756044.1 CDS envZ NC_004431.1 3961381 3962733 R membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein complement(3961381..3962733) Escherichia coli CFT073 1036734 NP_756045.1 CDS ompR NC_004431.1 3962730 3963449 R part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator complement(3962730..3963449) Escherichia coli CFT073 1036818 NP_756046.1 CDS c4182 NC_004431.1 3963539 3963724 R hypothetical protein complement(3963539..3963724) Escherichia coli CFT073 1036821 NP_756047.2 CDS greB NC_004431.1 3963677 3964153 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 3963677..3964153 Escherichia coli CFT073 1036741 NP_756048.1 CDS yhgF NC_004431.1 3964250 3966571 D Escherichia coli K-12 ortholog: b3407; Escherichia coli O157:H7 ortholog: z4762; hypothetical protein 3964250..3966571 Escherichia coli CFT073 1036794 NP_756049.1 CDS feoA NC_004431.1 3967027 3967254 D Escherichia coli K-12 ortholog: b3408; Escherichia coli O157:H7 ortholog: z4763; ferrous iron transport protein A 3967027..3967254 Escherichia coli CFT073 1036745 NP_756050.2 CDS feoB NC_004431.1 3967271 3969592 D cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 3967271..3969592 Escherichia coli CFT073 1036786 NP_756051.1 CDS yhgG NC_004431.1 3969583 3969828 D Escherichia coli K-12 ortholog: b3410; Escherichia coli O157:H7 ortholog: z4765; hypothetical protein 3969583..3969828 Escherichia coli CFT073 1036850 NP_756052.1 CDS yhgA NC_004431.1 3970061 3970654 D Escherichia coli K-12 ortholog: b3411; Escherichia coli O157:H7 ortholog: z4766; hypothetical protein 3970061..3970654 Escherichia coli CFT073 1036851 NP_756053.1 CDS bioH NC_004431.1 3970683 3971453 R Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH complement(3970683..3971453) Escherichia coli CFT073 1036795 NP_756054.2 CDS yhgH NC_004431.1 3971491 3972174 D involved in high-affinity gluconate transport; gluconate periplasmic binding protein 3971491..3972174 Escherichia coli CFT073 1036787 NP_756055.1 CDS yhgI NC_004431.1 3972233 3972808 D cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein 3972233..3972808 Escherichia coli CFT073 1036834 NP_756056.1 CDS gntT NC_004431.1 3973172 3974488 D Gluconate permease; Escherichia coli K-12 ortholog: b3415; Escherichia coli O157:H7 ortholog: z4770; high-affinity gluconate transporter 3973172..3974488 Escherichia coli CFT073 1036804 NP_756057.1 CDS malQ NC_004431.1 3974599 3976683 R amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase complement(3974599..3976683) Escherichia coli CFT073 1036762 NP_756058.1 CDS malP NC_004431.1 3976693 3979086 R Escherichia coli K-12 ortholog: b3417; Escherichia coli O157:H7 ortholog: z4772; maltodextrin phosphorylase complement(3976693..3979086) Escherichia coli CFT073 1036869 NP_756059.1 CDS c4195 NC_004431.1 3979431 3979577 R hypothetical protein complement(3979431..3979577) Escherichia coli CFT073 1036872 NP_756060.1 CDS malT NC_004431.1 3979709 3982414 D Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 3979709..3982414 Escherichia coli CFT073 1036838 NP_756061.1 CDS c4197 NC_004431.1 3982457 3983476 R catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase complement(3982457..3983476) Escherichia coli CFT073 1036815 NP_756062.1 CDS rtcB NC_004431.1 3983477 3984766 R Escherichia coli K-12 ortholog: b3421; Escherichia coli O157:H7 ortholog: z4779; protein rtcB complement(3983477..3984766) Escherichia coli CFT073 1036860 NP_756063.1 CDS rtcR NC_004431.1 3984892 3986490 D Escherichia coli K-12 ortholog: b3422; Escherichia coli O157:H7 ortholog: z4780; transcriptional regulatory protein rtcR 3984892..3986490 Escherichia coli CFT073 1036845 NP_756064.1 CDS glpR NC_004431.1 3986472 3987281 R represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR complement(3986472..3987281) Escherichia coli CFT073 1036800 NP_756065.1 CDS glpG NC_004431.1 3987247 3988077 R protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG complement(3987247..3988077) Escherichia coli CFT073 1036898 NP_756066.2 CDS glpE NC_004431.1 3988122 3988448 R belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase complement(3988122..3988448) Escherichia coli CFT073 1036899 NP_756067.2 CDS glpD NC_004431.1 3988638 3990143 D in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 3988638..3990143 Escherichia coli CFT073 1036866 NP_756068.1 CDS c4204 NC_004431.1 3990197 3990802 R Escherichia coli O157:H7 ortholog: z4787; hypothetical protein complement(3990197..3990802) Escherichia coli CFT073 1036846 NP_756069.1 CDS c4205 NC_004431.1 3990805 3991572 R hypothetical protein complement(3990805..3991572) Escherichia coli CFT073 1036895 NP_756070.1 CDS c4206 NC_004431.1 3991575 3992285 R hypothetical protein complement(3991575..3992285) Escherichia coli CFT073 1036867 NP_756071.1 CDS c4207 NC_004431.1 3992579 3993589 R Residues 41 to 313 of 336 are 27.40 pct identical to residues 28 to 290 of 351 from GenPept.129 : >gb|AAG58691.1|AE005581_3 (AE005581) fimbrial protein [Escherichia coli O157:H7 EDL933]; fimbrial adhesin complement(3992579..3993589) Escherichia coli CFT073 1036843 NP_756072.1 CDS c4208 NC_004431.1 3993608 3994405 R Residues 27 to 251 of 265 are 37.61 pct identical to residues 15 to 230 of 234 from GenPept.129 : >emb|CAD01181.1| (AL627265) fimbrial chaperone [Salmonella enterica subsp. enterica serovar Typhi]; fimbrial chaperone complement(3993608..3994405) Escherichia coli CFT073 1036882 NP_756073.1 CDS c4209 NC_004431.1 3994350 3994907 R Residues 5 to 185 of 185 are 32.24 pct identical to residues 7 to 187 of 187 from GenPept.129 : >gb|AAG55429.1|AE005284_7 (AE005284) fimbrial-like protein [Escherichia coli O157:H7 EDL933]; minor fimbrial subunit complement(3994350..3994907) Escherichia coli CFT073 1036926 NP_756074.1 CDS c4210 NC_004431.1 3994873 3995325 R Residues 1 to 150 of 150 are 32.69 pct identical to residues 36 to 181 of 181 from GenPept.129 : >gb|AAL18989.1| (AE008694) fimbrial subunit [Salmonella typhimurium LT2]; minor fimbrial subunit complement(3994873..3995325) Escherichia coli CFT073 1036887 NP_756075.1 CDS c4211 NC_004431.1 3995303 3995464 D hypothetical protein 3995303..3995464 Escherichia coli CFT073 1036863 NP_756076.1 CDS ycbS NC_004431.1 3995436 3998030 R Escherichia coli K-12 ortholog: b0940; Escherichia coli O157:H7 ortholog: z5915; outer membrane usher protein ycbS complement(3995436..3998030) Escherichia coli CFT073 1036923 NP_756077.1 CDS c4213 NC_004431.1 3998067 3998846 R Escherichia coli K-12 ortholog: b4316; Escherichia coli O157:H7 ortholog: z2201; chaperone protein fimC complement(3998067..3998846) Escherichia coli CFT073 1036893 NP_756078.1 CDS c4214 NC_004431.1 3998920 3999624 R Residues 56 to 234 of 234 are 32.96 pct identical to residues 26 to 178 of 178 from GenPept.129 : >gb|AAL22500.1| (AE008868) long polar fimbria [Salmonella typhimurium LT2]; major fimbrial subunit complement(3998920..3999624) Escherichia coli CFT073 1036874 NP_756079.1 CDS glgP NC_004431.1 4000119 4002566 R Escherichia coli K-12 ortholog: b3428; Escherichia coli O157:H7 ortholog: z4790; glycogen phosphorylase complement(4000119..4002566) Escherichia coli CFT073 1036949 NP_756080.1 CDS glgA NC_004431.1 4002585 4004018 R catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase complement(4002585..4004018) Escherichia coli CFT073 1036951 NP_756081.2 CDS glgC NC_004431.1 4004018 4005313 R catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase complement(4004018..4005313) Escherichia coli CFT073 1036924 NP_756082.1 CDS glgX NC_004431.1 4005331 4007304 R catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching enzyme complement(4005331..4007304) Escherichia coli CFT073 1036916 NP_756083.1 CDS glgB NC_004431.1 4007301 4009487 R catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme complement(4007301..4009487) Escherichia coli CFT073 1036905 NP_756084.2 CDS asd NC_004431.1 4009760 4010863 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(4009760..4010863) Escherichia coli CFT073 1036947 NP_756085.1 CDS yhgN NC_004431.1 4011055 4011648 D YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); dITP- and XTP- hydrolase 4011055..4011648 Escherichia coli CFT073 1036901 NP_756086.1 CDS c4222 NC_004431.1 4011694 4012989 R Escherichia coli O157:H7 ortholog: z4799; DNA processing protein complement(4011694..4012989) Escherichia coli CFT073 1036927 NP_756087.1 CDS c4223 NC_004431.1 4012896 4014995 R Residues 6 to 340 of 699 are 37.53 pct identical to residues 14 to 331 of 610 from MG1655 : b3822; hypothetical protein complement(4012896..4014995) Escherichia coli CFT073 1036979 NP_756088.1 CDS gntU NC_004431.1 4015133 4016473 R Escherichia coli K-12 ortholog: b3436; Escherichia coli O157:H7 ortholog: z4804; low affinity gluconate transporter complement(4015133..4016473) Escherichia coli CFT073 1036952 NP_756089.2 CDS gntK NC_004431.1 4016477 4017004 R thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase 1 complement(4016477..4017004) Escherichia coli CFT073 1036939 NP_756090.1 CDS c4226 NC_004431.1 4016531 4017163 D hypothetical protein 4016531..4017163 Escherichia coli CFT073 1036937 NP_756091.1 CDS gntR NC_004431.1 4017143 4018138 R Escherichia coli K-12 ortholog: b3438; Escherichia coli O157:H7 ortholog: z4806; gluconate utilization system GNT-I transcriptional repressor complement(4017143..4018138) Escherichia coli CFT073 1036975 NP_756092.1 CDS yhhW NC_004431.1 4018231 4018926 R Escherichia coli K-12 ortholog: b3439; Escherichia coli O157:H7 ortholog: z4807; hypothetical protein complement(4018231..4018926) Escherichia coli CFT073 1036964 NP_756093.1 CDS yhhX NC_004431.1 4019049 4020086 R Escherichia coli K-12 ortholog: b3440; Escherichia coli O157:H7 ortholog: z4808; dehydrogenase complement(4019049..4020086) Escherichia coli CFT073 1036945 NP_756094.1 CDS c4230 NC_004431.1 4020033 4020191 D hypothetical protein 4020033..4020191 Escherichia coli CFT073 1036928 NP_756095.1 CDS yhhZ NC_004431.1 4021144 4022322 D Escherichia coli K-12 ortholog: b3442; hypothetical protein 4021144..4022322 Escherichia coli CFT073 1036961 NP_756096.1 CDS yrhA NC_004431.1 4022319 4022813 D Escherichia coli K-12 ortholog: b3443; hypothetical protein 4022319..4022813 Escherichia coli CFT073 1037009 NP_756097.1 CDS yrhB NC_004431.1 4023263 4023547 D Escherichia coli K-12 ortholog: b3446; hypothetical protein 4023263..4023547 Escherichia coli CFT073 1036992 NP_756098.1 CDS ggt NC_004431.1 4023585 4025318 R periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase complement(4023585..4025318) Escherichia coli CFT073 1036970 NP_756099.1 CDS yhhA NC_004431.1 4025438 4025878 D ORFQ; Escherichia coli K-12 ortholog: b3448; Escherichia coli O157:H7 ortholog: z4815; hypothetical protein 4025438..4025878 Escherichia coli CFT073 1036972 NP_756100.1 CDS ugpQ NC_004431.1 4025865 4026608 R hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; cytoplasmic glycerophosphodiester phosphodiesterase complement(4025865..4026608) Escherichia coli CFT073 1036999 NP_756101.2 CDS ugpC NC_004431.1 4026605 4027675 R part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit complement(4026605..4027675) Escherichia coli CFT073 1037016 NP_756102.1 CDS ugpE NC_004431.1 4027677 4028522 R with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein complement(4027677..4028522) Escherichia coli CFT073 1036988 NP_756103.1 CDS ugpA NC_004431.1 4028519 4029406 R with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease complement(4028519..4029406) Escherichia coli CFT073 1037034 NP_756104.1 CDS ugpB NC_004431.1 4029504 4030820 R with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein complement(4029504..4030820) Escherichia coli CFT073 1037036 NP_756105.1 CDS c4243 NC_004431.1 4031097 4031228 D hypothetical protein 4031097..4031228 Escherichia coli CFT073 1037018 NP_756106.2 CDS livF NC_004431.1 4031217 4031930 R with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(4031217..4031930) Escherichia coli CFT073 1037002 NP_756107.1 CDS livG NC_004431.1 4031932 4032699 R Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(4031932..4032699) Escherichia coli CFT073 1036995 NP_756108.1 CDS livM NC_004431.1 4032696 4033973 R Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit complement(4032696..4033973) Escherichia coli CFT073 1036993 NP_756109.1 CDS livH NC_004431.1 4033970 4034896 R LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH complement(4033970..4034896) Escherichia coli CFT073 1037053 NP_756110.1 CDS livK NC_004431.1 4034944 4036107 R LS-BP; Escherichia coli K-12 ortholog: b3458; Escherichia coli O157:H7 ortholog: z4829; leucine-specific binding protein complement(4034944..4036107) Escherichia coli CFT073 1037043 NP_756111.1 CDS c4249 NC_004431.1 4036080 4036226 D hypothetical protein 4036080..4036226 Escherichia coli CFT073 1037054 NP_756112.1 CDS c4250 NC_004431.1 4036205 4036342 R hypothetical protein complement(4036205..4036342) Escherichia coli CFT073 1037055 NP_756113.1 CDS yhhK NC_004431.1 4036477 4036860 D Escherichia coli K-12 ortholog: b3459; Escherichia coli O157:H7 ortholog: z4831; hypothetical protein 4036477..4036860 Escherichia coli CFT073 1037022 NP_756114.1 CDS c4252 NC_004431.1 4036870 4036992 D Residues 4 to 40 of 40 are 91.89 pct identical to residues 134 to 170 of 170 from GenPept.129 : >gb|AAA83882.1| (J05516) ORF19; [Escherichia coli]; hypothetical protein 4036870..4036992 Escherichia coli CFT073 1037083 NP_756115.1 CDS livJ NC_004431.1 4037048 4038208 R LIV-BP; Escherichia coli K-12 ortholog: b3460; Escherichia coli O157:H7 ortholog: z4834; Leu/Ile/Val-binding protein complement(4037048..4038208) Escherichia coli CFT073 1037007 NP_756116.1 CDS rpoH NC_004431.1 4038422 4039276 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(4038422..4039276) Escherichia coli CFT073 1037023 NP_756117.2 CDS ftsX NC_004431.1 4039521 4040579 R ABC transporter, membrane protein; cell division protein FtsX complement(4039521..4040579) Escherichia coli CFT073 1037013 NP_756118.1 CDS ftsE NC_004431.1 4040572 4041240 R ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE complement(4040572..4041240) Escherichia coli CFT073 1037070 NP_756119.1 CDS ftsY NC_004431.1 4041243 4042739 R signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY complement(4041243..4042739) Escherichia coli CFT073 1037073 NP_756120.1 CDS rsmD NC_004431.1 4042889 4043485 D catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 4042889..4043485 Escherichia coli CFT073 1037074 NP_756121.1 CDS yhhL NC_004431.1 4043472 4043744 D Escherichia coli K-12 ortholog: b3466; Escherichia coli O157:H7 ortholog: z4840; hypothetical protein 4043472..4043744 Escherichia coli CFT073 1037056 NP_756122.1 CDS yhhM NC_004431.1 4043747 4044106 R Escherichia coli K-12 ortholog: b3467; Escherichia coli O157:H7 ortholog: z4841; hypothetical protein complement(4043747..4044106) Escherichia coli CFT073 1037072 NP_756123.1 CDS yhhN NC_004431.1 4044247 4044873 D Escherichia coli K-12 ortholog: b3468; Escherichia coli O157:H7 ortholog: z4842; hypothetical protein 4044247..4044873 Escherichia coli CFT073 1037045 NP_756124.1 CDS zntA NC_004431.1 4044947 4047145 D P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 4044947..4047145 Escherichia coli CFT073 1037032 NP_756125.1 CDS yhhP NC_004431.1 4047406 4047651 R TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA complement(4047406..4047651) Escherichia coli CFT073 1037050 NP_756126.1 CDS yhhQ NC_004431.1 4047872 4048537 D Escherichia coli K-12 ortholog: b3471; Escherichia coli O157:H7 ortholog: z4845; hypothetical protein 4047872..4048537 Escherichia coli CFT073 1037075 NP_756127.2 CDS c4265 NC_004431.1 4048610 4049167 D Escherichia coli K-12 ortholog: b3472; Escherichia coli O157:H7 ortholog: z4846; hypothetical protein 4048610..4049167 Escherichia coli CFT073 1037095 NP_756128.2 CDS yhhS NC_004431.1 4049171 4050388 R Escherichia coli K-12 ortholog: b3473; Escherichia coli O157:H7 ortholog: z4847; major facilitator superfamily transporter complement(4049171..4050388) Escherichia coli CFT073 1037064 NP_756129.1 CDS yhhT NC_004431.1 4050439 4051569 D Escherichia coli K-12 ortholog: b3474; Escherichia coli O157:H7 ortholog: z4848; hypothetical protein 4050439..4051569 Escherichia coli CFT073 1037123 NP_756130.1 CDS yhhU NC_004431.1 4051624 4052211 D Escherichia coli K-12 ortholog: b3475; Escherichia coli O157:H7 ortholog: z4867; holo-(acyl carrier protein) synthase 2 4051624..4052211 Escherichia coli CFT073 1037124 NP_756131.1 CDS nikA NC_004431.1 4052322 4053896 D Escherichia coli K-12 ortholog: b3476; Escherichia coli O157:H7 ortholog: z4868; nickel-binding periplasmic protein 4052322..4053896 Escherichia coli CFT073 1037086 NP_756132.1 CDS nikB NC_004431.1 4053896 4054840 D with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 4053896..4054840 Escherichia coli CFT073 1037079 NP_756133.1 CDS nikC NC_004431.1 4054837 4055670 D with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 4054837..4055670 Escherichia coli CFT073 1037069 NP_756134.1 CDS nikD NC_004431.1 4055670 4056434 D with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 4055670..4056434 Escherichia coli CFT073 1037139 NP_756135.1 CDS nikE NC_004431.1 4056431 4057237 D with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 4056431..4057237 Escherichia coli CFT073 1037104 NP_756136.1 CDS yhhG NC_004431.1 4057243 4057644 D Inhibits transcription at high concentrations of nickel; nickel responsive regulator 4057243..4057644 Escherichia coli CFT073 1037108 NP_756137.1 CDS c4275 NC_004431.1 4057486 4057617 R hypothetical protein complement(4057486..4057617) Escherichia coli CFT073 1037082 NP_756138.1 CDS c4276 NC_004431.1 4057834 4058589 D Escherichia coli O157:H7 ortholog: z4874; regulator 4057834..4058589 Escherichia coli CFT073 1037136 NP_756139.1 CDS c4277 NC_004431.1 4058602 4059087 D Escherichia coli O157:H7 ortholog: z4875; phosphotransferase system enzyme subunit 4058602..4059087 Escherichia coli CFT073 1037132 NP_756140.1 CDS c4278 NC_004431.1 4059084 4059365 D Escherichia coli O157:H7 ortholog: z4876; phosphotransferase system enzyme subunit 4059084..4059365 Escherichia coli CFT073 1037097 NP_756141.1 CDS c4279 NC_004431.1 4059412 4060800 D EIIC-GAT; Escherichia coli K-12 ortholog: b2092; Escherichia coli O157:H7 ortholog: z4877; PTS system, galactitol-specific IIC component 4059412..4060800 Escherichia coli CFT073 1037116 NP_756142.1 CDS c4280 NC_004431.1 4060793 4062241 D Escherichia coli O157:H7 ortholog: z4878; xylulose kinase 4060793..4062241 Escherichia coli CFT073 1037147 NP_756143.1 CDS c4281 NC_004431.1 4062119 4062514 R hypothetical protein complement(4062119..4062514) Escherichia coli CFT073 1037143 NP_756144.1 CDS c4282 NC_004431.1 4062169 4062300 D Residues 1 to 43 of 43 are 95.34 pct identical to residues 460 to 502 of 502 from GenPept.129 : >gb|AAG58613.1|AE005572_11 (AE005572) xylulose kinase [Escherichia coli O157:H7 EDL933]; hypothetical protein 4062169..4062300 Escherichia coli CFT073 1037149 NP_756145.1 CDS c4283 NC_004431.1 4062290 4062559 D Escherichia coli O157:H7 ortholog: z4879; phosphocarrier protein 4062290..4062559 Escherichia coli CFT073 1037150 NP_756146.1 CDS gatY NC_004431.1 4062591 4063442 D class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 4062591..4063442 Escherichia coli CFT073 1037131 NP_756147.1 CDS yhhJ NC_004431.1 4063552 4064760 R Escherichia coli K-12 ortholog: b3485; Escherichia coli O157:H7 ortholog: z4884; hypothetical protein complement(4063552..4064760) Escherichia coli CFT073 1037134 NP_756148.1 CDS yhiH NC_004431.1 4064676 4067411 R Escherichia coli K-12 ortholog: b3486; Escherichia coli O157:H7 ortholog: z4885; ABC transporter ATP-binding protein complement(4064676..4067411) Escherichia coli CFT073 1037117 NP_756149.1 CDS yhiI NC_004431.1 4067408 4068475 R Escherichia coli K-12 ortholog: b3487; Escherichia coli O157:H7 ortholog: z4886; hypothetical protein complement(4067408..4068475) Escherichia coli CFT073 1037127 NP_756150.1 CDS c4288 NC_004431.1 4068468 4068599 R hypothetical protein complement(4068468..4068599) Escherichia coli CFT073 1037126 NP_756151.1 CDS yhiM NC_004431.1 4069197 4070261 D Escherichia coli K-12 ortholog: b3491; Escherichia coli O157:H7 ortholog: z4890; hypothetical protein 4069197..4070261 Escherichia coli CFT073 1037157 NP_756152.1 CDS yhiN NC_004431.1 4070348 4071541 R Escherichia coli K-12 ortholog: b3492; Escherichia coli O157:H7 ortholog: z4891; hypothetical protein complement(4070348..4071541) Escherichia coli CFT073 1037159 NP_756153.1 CDS pitA NC_004431.1 4071773 4073272 D Escherichia coli K-12 ortholog: b3493; Escherichia coli O157:H7 ortholog: z4893; inorganic phosphate transporter 4071773..4073272 Escherichia coli CFT073 1037160 NP_756154.1 CDS yhiO NC_004431.1 4073343 4073678 R ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB complement(4073343..4073678) Escherichia coli CFT073 1037161 NP_756155.1 CDS uspA NC_004431.1 4074069 4074503 D Escherichia coli K-12 ortholog: b3495; Escherichia coli O157:H7 ortholog: z4895; universal stress protein A 4074069..4074503 Escherichia coli CFT073 1037151 NP_756156.1 CDS c4294 NC_004431.1 4074686 4074865 R hypothetical protein complement(4074686..4074865) Escherichia coli CFT073 1037171 NP_756157.1 CDS yhiP NC_004431.1 4074820 4076289 D member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 4074820..4076289 Escherichia coli CFT073 1037146 NP_756158.2 CDS yhiQ NC_004431.1 4076338 4077090 R predicted SAM-dependent methyltransferase; methyltransferase complement(4076338..4077090) Escherichia coli CFT073 1037144 NP_756159.1 CDS prlC NC_004431.1 4077098 4079179 R Escherichia coli K-12 ortholog: b3498; Escherichia coli O157:H7 ortholog: z4898; oligopeptidase A complement(4077098..4079179) Escherichia coli CFT073 1037168 NP_756160.1 CDS yhiR NC_004431.1 4079292 4080185 D Escherichia coli K-12 ortholog: b3499; Escherichia coli O157:H7 ortholog: z4899; hypothetical protein 4079292..4080185 Escherichia coli CFT073 1037164 NP_756161.1 CDS gor NC_004431.1 4080257 4081609 D catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 4080257..4081609 Escherichia coli CFT073 1037162 NP_756162.1 CDS c4300 NC_004431.1 4081663 4081812 R hypothetical protein complement(4081663..4081812) Escherichia coli CFT073 1037167 NP_756163.1 CDS arsC NC_004431.1 4082081 4082506 D Escherichia coli K-12 ortholog: b3503; Escherichia coli O157:H7 ortholog: z4905; arsenate reductase 4082081..4082506 Escherichia coli CFT073 1037172 NP_756164.1 CDS c4302 NC_004431.1 4082560 4082724 D Escherichia coli O157:H7 ortholog: z4906; hypothetical protein 4082560..4082724 Escherichia coli CFT073 1037152 NP_756165.1 CDS c4303 NC_004431.1 4083123 4083296 D Residues 1 to 53 of 57 are 86.79 pct identical to residues 1 to 53 of 260 from MG1655 : b3504; hypothetical protein 4083123..4083296 Escherichia coli CFT073 1037154 NP_756166.1 CDS slp NC_004431.1 4083657 4084256 D Escherichia coli K-12 ortholog: b3506; Escherichia coli O157:H7 ortholog: z4908; outer membrane protein Slp 4083657..4084256 Escherichia coli CFT073 1037175 NP_756167.1 CDS c4305 NC_004431.1 4084297 4084470 D hypothetical protein 4084297..4084470 Escherichia coli CFT073 1037176 NP_756168.1 CDS yhiF NC_004431.1 4084409 4084939 D Escherichia coli K-12 ortholog: b3507; Escherichia coli O157:H7 ortholog: z4909; transcriptional regulator YhiF 4084409..4084939 Escherichia coli CFT073 1037178 NP_756169.1 CDS chuS NC_004431.1 4084996 4086024 R Escherichia coli O157:H7 ortholog: z4910; heme/hemoglobin transport protein complement(4084996..4086024) Escherichia coli CFT073 1037174 NP_756170.1 CDS chuA NC_004431.1 4086073 4088019 R Escherichia coli O157:H7 ortholog: z4911; outer membrane heme/hemoglobin receptor complement(4086073..4088019) Escherichia coli CFT073 1037196 NP_756171.1 CDS c4309 NC_004431.1 4087994 4088152 D hypothetical protein 4087994..4088152 Escherichia coli CFT073 1037180 NP_756172.1 CDS c4310 NC_004431.1 4088156 4088341 R hypothetical protein complement(4088156..4088341) Escherichia coli CFT073 1037163 NP_756173.1 CDS c4311 NC_004431.1 4088424 4088585 D hypothetical protein 4088424..4088585 Escherichia coli CFT073 1037184 NP_756174.1 CDS c4312 NC_004431.1 4088467 4088616 R Residues 1 to 48 of 49 are 79.16 pct identical to residues 1 to 48 of 94 from GenPept.129 : >gb|AAG58642.1|AE005576_1 (AE005576) Z4912 gene product [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(4088467..4088616) Escherichia coli CFT073 1037192 NP_756175.1 CDS chuT NC_004431.1 4088661 4089653 D Escherichia coli O157:H7 ortholog: z4913; periplasmic binding protein 4088661..4089653 Escherichia coli CFT073 1037179 NP_756176.1 CDS chuW NC_004431.1 4089673 4091010 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4089673..4091010 Escherichia coli CFT073 1037191 NP_756177.1 CDS chuX NC_004431.1 4091023 4091517 D Escherichia coli O157:H7 ortholog: z4915; hypothetical protein 4091023..4091517 Escherichia coli CFT073 1037205 NP_756178.1 CDS chuY NC_004431.1 4091517 4092140 D Escherichia coli O157:H7 ortholog: z4917; hypothetical protein 4091517..4092140 Escherichia coli CFT073 1037194 NP_756179.1 CDS chuU NC_004431.1 4092189 4093181 D Escherichia coli O157:H7 ortholog: z4918; iron ABC transporter permease 4092189..4093181 Escherichia coli CFT073 1037170 NP_756180.1 CDS hmuV NC_004431.1 4093148 4093948 D with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 4093148..4093948 Escherichia coli CFT073 1037200 NP_756181.1 CDS yhiD NC_004431.1 4094000 4094647 R inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; Mg(2+) transport ATPase complement(4094000..4094647) Escherichia coli CFT073 1037199 NP_756182.1 CDS hdeB NC_004431.1 4094711 4095049 R 10K-L protein; Escherichia coli K-12 ortholog: b3509; Escherichia coli O157:H7 ortholog: z4921; acid-resistance protein complement(4094711..4095049) Escherichia coli CFT073 1037197 NP_756183.1 CDS hdeA NC_004431.1 4095153 4095485 R inactive form; acid-resistance protein complement(4095153..4095485) Escherichia coli CFT073 1037202 NP_756184.1 CDS hdeD NC_004431.1 4095740 4096312 D Escherichia coli K-12 ortholog: b3511; Escherichia coli O157:H7 ortholog: z4923; acid-resistance membrane protein 4095740..4096312 Escherichia coli CFT073 1037203 NP_756185.1 CDS yhiE NC_004431.1 4097033 4097638 D Escherichia coli K-12 ortholog: b3512; Escherichia coli O157:H7 ortholog: z4925; hypothetical protein 4097033..4097638 Escherichia coli CFT073 1037206 NP_756186.1 CDS yhiU NC_004431.1 4097977 4099134 D with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 4097977..4099134 Escherichia coli CFT073 1037183 NP_756187.1 CDS yhiV NC_004431.1 4099159 4102272 D Escherichia coli K-12 ortholog: b3514; Escherichia coli O157:H7 ortholog: z4927; hypothetical protein 4099159..4102272 Escherichia coli CFT073 1037186 NP_756188.1 CDS yhiW NC_004431.1 4102635 4103363 R Escherichia coli K-12 ortholog: b3515; Escherichia coli O157:H7 ortholog: z4928; transcriptional regulator YhiW complement(4102635..4103363) Escherichia coli CFT073 1037214 NP_756189.1 CDS yhiX NC_004431.1 4103732 4104556 R regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX complement(4103732..4104556) Escherichia coli CFT073 1037207 NP_756190.1 CDS gadA NC_004431.1 4104924 4106387 R Escherichia coli K-12 ortholog: b3517; Escherichia coli O157:H7 ortholog: z4930; glutamate decarboxylase alpha complement(4104924..4106387) Escherichia coli CFT073 1037216 NP_756191.1 CDS yhjA NC_004431.1 4106535 4107932 R Escherichia coli K-12 ortholog: b3518; Escherichia coli O157:H7 ortholog: z4931; cytochrome C peroxidase complement(4106535..4107932) Escherichia coli CFT073 1037210 NP_756192.1 CDS treF NC_004431.1 4108337 4109986 D cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 4108337..4109986 Escherichia coli CFT073 1037213 NP_756193.1 CDS yhjB NC_004431.1 4110037 4110639 R Escherichia coli K-12 ortholog: b3520; Escherichia coli O157:H7 ortholog: z4933; transcriptional regulator YhjB complement(4110037..4110639) Escherichia coli CFT073 1037230 NP_756194.1 CDS yhjC NC_004431.1 4111087 4112058 D Escherichia coli K-12 ortholog: b3521; Escherichia coli O157:H7 ortholog: z4934; transcriptional regulator YhjC 4111087..4112058 Escherichia coli CFT073 1037218 NP_756195.1 CDS yhjD NC_004431.1 4112107 4113120 D Escherichia coli K-12 ortholog: b3522; Escherichia coli O157:H7 ortholog: z4935; hypothetical protein 4112107..4113120 Escherichia coli CFT073 1037217 NP_756196.1 CDS yhjE NC_004431.1 4113513 4114835 D Escherichia coli K-12 ortholog: b3523; Escherichia coli O157:H7 ortholog: z4936; metabolite transport protein 4113513..4114835 Escherichia coli CFT073 1037229 NP_756197.1 CDS yhjG NC_004431.1 4115014 4117089 R Escherichia coli K-12 ortholog: b3524; Escherichia coli O157:H7 ortholog: z4937; hypothetical protein complement(4115014..4117089) Escherichia coli CFT073 1037239 NP_756198.1 CDS yhjH NC_004431.1 4117144 4117914 R in Escherichia coli this protein is involved in flagellar function; diguanylate phosphodiesterase complement(4117144..4117914) Escherichia coli CFT073 1037219 NP_756199.1 CDS kdgK NC_004431.1 4117795 4119072 D Escherichia coli K-12 ortholog: b3526; Escherichia coli O157:H7 ortholog: z4940; 2-dehydro-3-deoxygluconokinase 4117795..4119072 Escherichia coli CFT073 1037228 YP_004853828.1 CDS c4338 NC_004431.1 4117880 4118059 D hypothetical protein 4117880..4118059 Escherichia coli CFT073 1037261 NP_756201.1 CDS yhjJ NC_004431.1 4119168 4120664 R Escherichia coli K-12 ortholog: b3527; Escherichia coli O157:H7 ortholog: z4941; hypothetical protein complement(4119168..4120664) Escherichia coli CFT073 1037241 NP_756202.1 CDS dctA NC_004431.1 4120884 4122170 R involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA complement(4120884..4122170) Escherichia coli CFT073 1037204 NP_756203.2 CDS yhjK NC_004431.1 4122353 4124308 R HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase protein from E. coli; phosphodiesterase complement(4122353..4124308) Escherichia coli CFT073 1037258 NP_756204.1 CDS yhjL NC_004431.1 4124423 4127896 R cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC complement(4124423..4127896) Escherichia coli CFT073 1037248 NP_756205.1 CDS yhjM NC_004431.1 4127878 4128990 R catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase complement(4127878..4128990) Escherichia coli CFT073 1037238 NP_756206.1 CDS yhjN NC_004431.1 4128991 4131417 R binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein complement(4128991..4131417) Escherichia coli CFT073 1037255 NP_756207.2 CDS bcsA NC_004431.1 4131341 4133959 R polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit complement(4131341..4133959) Escherichia coli CFT073 1037224 NP_756208.1 CDS yhjQ NC_004431.1 4133956 4134708 R Escherichia coli K-12 ortholog: b3534; Escherichia coli O157:H7 ortholog: z4949; cell division protein complement(4133956..4134708) Escherichia coli CFT073 1037280 NP_756209.1 CDS yhjR NC_004431.1 4134720 4134908 R Escherichia coli K-12 ortholog: b3535; Escherichia coli O157:H7 ortholog: z4951; hypothetical protein complement(4134720..4134908) Escherichia coli CFT073 1037221 NP_756210.1 CDS yhjS NC_004431.1 4135181 4136752 D Escherichia coli K-12 ortholog: b3536; Escherichia coli O157:H7 ortholog: z4952; hypothetical protein 4135181..4136752 Escherichia coli CFT073 1037291 NP_756211.1 CDS yhjT NC_004431.1 4136749 4136940 D Escherichia coli K-12 ortholog: b3537; Escherichia coli O157:H7 ortholog: z4953; hypothetical protein 4136749..4136940 Escherichia coli CFT073 1037282 NP_756212.1 CDS yhjU NC_004431.1 4136937 4138616 D Escherichia coli K-12 ortholog: b3538; Escherichia coli O157:H7 ortholog: z4954; hypothetical protein 4136937..4138616 Escherichia coli CFT073 1037263 NP_756213.1 CDS c4351 NC_004431.1 4138702 4138944 R Escherichia coli O157:H7 ortholog: z4955; hypothetical protein complement(4138702..4138944) Escherichia coli CFT073 1037288 NP_756214.1 CDS c4352 NC_004431.1 4139049 4139240 D hypothetical protein 4139049..4139240 Escherichia coli CFT073 1037352 NP_756215.1 CDS c4353 NC_004431.1 4139457 4139618 R hypothetical protein complement(4139457..4139618) Escherichia coli CFT073 1037292 NP_756216.1 CDS yhjV NC_004431.1 4139705 4141039 D Escherichia coli K-12 ortholog: b3539; Escherichia coli O157:H7 ortholog: z4956; transport protein YhjV 4139705..4141039 Escherichia coli CFT073 1037313 NP_756217.1 CDS dppF NC_004431.1 4141069 4142073 R Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit complement(4141069..4142073) Escherichia coli CFT073 1037240 NP_756218.1 CDS dppD NC_004431.1 4142070 4143053 R DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit complement(4142070..4143053) Escherichia coli CFT073 1037319 NP_756219.1 CDS dppC NC_004431.1 4143064 4143966 R Escherichia coli K-12 ortholog: b3542; Escherichia coli O157:H7 ortholog: z4959; dipeptide transporter complement(4143064..4143966) Escherichia coli CFT073 1037340 NP_756220.1 CDS dppB NC_004431.1 4143976 4144995 R transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB complement(4143976..4144995) Escherichia coli CFT073 1037294 YP_004853829.1 CDS c4359 NC_004431.1 4144958 4145329 D hypothetical protein 4144958..4145329 Escherichia coli CFT073 1037327 YP_004853830.1 CDS c4360 NC_004431.1 4145013 4145240 D hypothetical protein 4145013..4145240 Escherichia coli CFT073 1037329 NP_756223.1 CDS dppA NC_004431.1 4145302 4146909 R Dipeptide-binding protein; Escherichia coli K-12 ortholog: b3544; Escherichia coli O157:H7 ortholog: z4961; periplasmic dipeptide transport protein complement(4145302..4146909) Escherichia coli CFT073 1037335 YP_004853831.1 CDS c4362 NC_004431.1 4147098 4147253 D hypothetical protein 4147098..4147253 Escherichia coli CFT073 1037350 YP_004853832.1 CDS c4363 NC_004431.1 4147261 4147770 R hypothetical protein complement(4147261..4147770) Escherichia coli CFT073 1037277 NP_756226.2 CDS yhjW NC_004431.1 4147821 4149512 R catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase complement(4147821..4149512) Escherichia coli CFT073 1037384 NP_756227.1 CDS yhjX NC_004431.1 4149836 4151044 R Escherichia coli K-12 ortholog: b3547; Escherichia coli O157:H7 ortholog: z4972; hypothetical protein complement(4149836..4151044) Escherichia coli CFT073 1037374 NP_756228.1 CDS yhjY NC_004431.1 4151273 4151977 R Escherichia coli K-12 ortholog: b3548; Escherichia coli O157:H7 ortholog: z4973; hypothetical protein complement(4151273..4151977) Escherichia coli CFT073 1037375 NP_756229.2 CDS tag NC_004431.1 4152129 4152692 D constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyl-adenine DNA glycosylase I 4152129..4152692 Escherichia coli CFT073 1037396 NP_756230.1 CDS yiaC NC_004431.1 4152689 4153129 D Escherichia coli K-12 ortholog: b3550; Escherichia coli O157:H7 ortholog: z4975; hypothetical protein 4152689..4153129 Escherichia coli CFT073 1037389 NP_756231.1 CDS bisC NC_004431.1 4153098 4155431 R Escherichia coli K-12 ortholog: b3551; Escherichia coli O157:H7 ortholog: z4976; biotin sulfoxide reductase complement(4153098..4155431) Escherichia coli CFT073 1037312 NP_756232.1 CDS yiaD NC_004431.1 4155584 4156243 D Escherichia coli K-12 ortholog: b3552; Escherichia coli O157:H7 ortholog: z4977; outer membrane lipoprotein 4155584..4156243 Escherichia coli CFT073 1037473 NP_756233.1 CDS c4371 NC_004431.1 4156259 4156384 D hypothetical protein 4156259..4156384 Escherichia coli CFT073 1037439 NP_756234.2 CDS yiaE NC_004431.1 4156347 4157321 D Involved in the metabolism of aromatic amino acids; 2-hydroxyacid dehydrogenase 4156347..4157321 Escherichia coli CFT073 1037406 NP_756235.1 CDS yiaF NC_004431.1 4157371 4158201 R Escherichia coli K-12 ortholog: b3554; Escherichia coli O157:H7 ortholog: z4979; hypothetical protein complement(4157371..4158201) Escherichia coli CFT073 1037397 NP_756236.1 CDS c4374 NC_004431.1 4158236 4158385 D hypothetical protein 4158236..4158385 Escherichia coli CFT073 1037392 NP_756237.1 CDS c4375 NC_004431.1 4158515 4158805 D Escherichia coli K-12 ortholog: b3555; Escherichia coli O157:H7 ortholog: z4980; transcriptional regulator 4158515..4158805 Escherichia coli CFT073 1037386 NP_756238.1 CDS c4376 NC_004431.1 4159023 4159385 R hypothetical protein complement(4159023..4159385) Escherichia coli CFT073 1037437 NP_756239.1 CDS cspA NC_004431.1 4159086 4159298 D CSP-A; Escherichia coli K-12 ortholog: b3556; Escherichia coli O157:H7 ortholog: z4981; major cold shock protein 4159086..4159298 Escherichia coli CFT073 1037378 NP_756240.1 CDS glyS NC_004431.1 4159961 4162030 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(4159961..4162030) Escherichia coli CFT073 1037405 NP_756241.1 CDS glyQ NC_004431.1 4162040 4162951 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(4162040..4162951) Escherichia coli CFT073 1037440 NP_756242.1 CDS c4380 NC_004431.1 4163046 4163345 R Escherichia coli O157:H7 ortholog: z4985; hypothetical protein complement(4163046..4163345) Escherichia coli CFT073 1037562 NP_756243.1 CDS yiaH NC_004431.1 4163520 4164515 D Escherichia coli K-12 ortholog: b3561; Escherichia coli O157:H7 ortholog: z4986; hypothetical protein 4163520..4164515 Escherichia coli CFT073 1037411 NP_756244.1 CDS yiaA NC_004431.1 4164557 4164997 R Escherichia coli K-12 ortholog: b3562; Escherichia coli O157:H7 ortholog: z4987; hypothetical protein complement(4164557..4164997) Escherichia coli CFT073 1037408 NP_756245.1 CDS yiaB NC_004431.1 4165040 4165423 R Escherichia coli K-12 ortholog: b3563; Escherichia coli O157:H7 ortholog: z4988; hypothetical protein complement(4165040..4165423) Escherichia coli CFT073 1037566 NP_756246.1 CDS xylB NC_004431.1 4165550 4167004 R Escherichia coli K-12 ortholog: b3564; Escherichia coli O157:H7 ortholog: z4989; xylulokinase complement(4165550..4167004) Escherichia coli CFT073 1037451 NP_756247.2 CDS xylA NC_004431.1 4167076 4168398 R catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase complement(4167076..4168398) Escherichia coli CFT073 1037435 NP_756248.1 CDS xylF NC_004431.1 4168686 4169756 D periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 4168686..4169756 Escherichia coli CFT073 1037599 NP_756249.2 CDS xylG NC_004431.1 4169834 4171375 D with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 4169834..4171375 Escherichia coli CFT073 1037600 NP_756250.1 CDS xylH NC_004431.1 4171353 4172534 D Escherichia coli K-12 ortholog: b3568; Escherichia coli O157:H7 ortholog: z4993; xylose transport system permease xylH 4171353..4172534 Escherichia coli CFT073 1037602 NP_756251.1 CDS xylR NC_004431.1 4172612 4173790 D Escherichia coli K-12 ortholog: b3569; Escherichia coli O157:H7 ortholog: z4994; xylose operon regulatory protein 4172612..4173790 Escherichia coli CFT073 1037569 NP_756252.1 CDS bax NC_004431.1 4173898 4174722 R Escherichia coli K-12 ortholog: b3570; Escherichia coli O157:H7 ortholog: z4995; hypothetical protein complement(4173898..4174722) Escherichia coli CFT073 1037612 NP_756253.1 CDS c4391 NC_004431.1 4174872 4175045 D hypothetical protein 4174872..4175045 Escherichia coli CFT073 1037474 NP_756254.1 CDS malS NC_004431.1 4175042 4177072 D periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 4175042..4177072 Escherichia coli CFT073 1037563 NP_756255.2 CDS avtA NC_004431.1 4177250 4178503 D transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 4177250..4178503 Escherichia coli CFT073 1037603 NP_756256.1 CDS yiaI NC_004431.1 4178655 4179134 R Escherichia coli K-12 ortholog: b3573; Escherichia coli O157:H7 ortholog: z4998; electron transport protein ysaA complement(4178655..4179134) Escherichia coli CFT073 1037610 NP_756257.1 CDS yiaJ NC_004431.1 4179230 4180078 R Escherichia coli K-12 ortholog: b3574; Escherichia coli O157:H7 ortholog: z2874; transcriptional regulator YiaJ complement(4179230..4180078) Escherichia coli CFT073 1037606 NP_756258.1 CDS yiaK NC_004431.1 4180279 4181277 D NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 4180279..4181277 Escherichia coli CFT073 1037613 NP_756259.1 CDS yiaL NC_004431.1 4181289 4181753 D Escherichia coli K-12 ortholog: b3576; hypothetical protein 4181289..4181753 Escherichia coli CFT073 1037601 NP_756260.1 CDS c4398 NC_004431.1 4181776 4182696 D Residues 4 to 305 of 306 are 76.72 pct identical to residues 3 to 307 of 310 from GenPept.129 : >gb|AAL22529.1| (AE008870) chemotaxis protein, resembles cheA [Salmonella typhimurium LT2]; hypothetical protein 4181776..4182696 Escherichia coli CFT073 1037589 NP_756261.1 CDS yiaM NC_004431.1 4182810 4183277 D membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO; 2,3-diketo-L-gulonate TRAP transporter small permease YiaM 4182810..4183277 Escherichia coli CFT073 1037597 NP_756262.1 CDS yiaN NC_004431.1 4183280 4184557 D Escherichia coli K-12 ortholog: b3578; hypothetical protein 4183280..4184557 Escherichia coli CFT073 1037621 NP_756263.1 CDS c4401 NC_004431.1 4184545 4184667 D hypothetical protein 4184545..4184667 Escherichia coli CFT073 1037617 NP_756264.1 CDS yiaO NC_004431.1 4184570 4185556 D Escherichia coli K-12 ortholog: b3579; Escherichia coli O157:H7 ortholog: z1284; ABC transporter periplasmic-binding protein 4184570..4185556 Escherichia coli CFT073 1037623 NP_756265.1 CDS lyxK NC_004431.1 4185560 4187056 D Escherichia coli K-12 ortholog: b3580; Cryptic L-xylulose kinase 4185560..4187056 Escherichia coli CFT073 1037624 NP_756266.1 CDS sgbH NC_004431.1 4187053 4187715 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate; 3-keto-L-gulonate-6-phosphate decarboxylase 4187053..4187715 Escherichia coli CFT073 1037608 NP_756267.1 CDS sgbU NC_004431.1 4187675 4188568 D L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase 4187675..4188568 Escherichia coli CFT073 1037703 NP_756268.1 CDS sgbE NC_004431.1 4188562 4189257 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4188562..4189257 Escherichia coli CFT073 1037607 NP_756269.1 CDS c4407 NC_004431.1 4188565 4189302 R hypothetical protein complement(4188565..4189302) Escherichia coli CFT073 1037620 NP_756270.1 CDS aldB NC_004431.1 4189304 4190932 R Escherichia coli K-12 ortholog: b3588; Escherichia coli O157:H7 ortholog: z5008; aldehyde dehydrogenase complement(4189304..4190932) Escherichia coli CFT073 1037660 NP_756271.1 CDS c4409 NC_004431.1 4190950 4192245 R Escherichia coli O157:H7 ortholog: z5009; hypothetical protein complement(4190950..4192245) Escherichia coli CFT073 1037709 NP_756272.1 CDS yiaY NC_004431.1 4192375 4193526 R Escherichia coli K-12 ortholog: b3589; Escherichia coli O157:H7 ortholog: z5010; alcohol dehydrogenase complement(4192375..4193526) Escherichia coli CFT073 1037622 NP_756273.1 CDS selB NC_004431.1 4193717 4195561 R SelB translation factor; Escherichia coli K-12 ortholog: b3590; Escherichia coli O157:H7 ortholog: z5011; selenocysteinyl-tRNA-specific translation factor complement(4193717..4195561) Escherichia coli CFT073 1037611 NP_756274.1 CDS selA NC_004431.1 4195558 4196949 R catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase complement(4195558..4196949) Escherichia coli CFT073 1037619 NP_756275.1 CDS yibF NC_004431.1 4197047 4197655 R Escherichia coli K-12 ortholog: b3592; Escherichia coli O157:H7 ortholog: z5013; glutathione S-transferase complement(4197047..4197655) Escherichia coli CFT073 1037650 NP_756276.1 CDS yibH NC_004431.1 4197726 4198862 R Escherichia coli K-12 ortholog: b3597; Escherichia coli O157:H7 ortholog: z5021; hypothetical protein complement(4197726..4198862) Escherichia coli CFT073 1037871 NP_756277.1 CDS yibI NC_004431.1 4198865 4199227 R Escherichia coli K-12 ortholog: b3598; Escherichia coli O157:H7 ortholog: z5022; hypothetical protein complement(4198865..4199227) Escherichia coli CFT073 1037926 NP_756278.1 CDS mtlA NC_004431.1 4199764 4201677 D EIIABC-MTL; Escherichia coli K-12 ortholog: b3599; Escherichia coli O157:H7 ortholog: z5023; PTS system, mannitol-specific IIABC component 4199764..4201677 Escherichia coli CFT073 1037930 NP_756279.1 CDS mtlD NC_004431.1 4201917 4203245 D Escherichia coli K-12 ortholog: b3600; Escherichia coli O157:H7 ortholog: z5024; mannitol-1-phosphate 5-dehydrogenase 4201917..4203245 Escherichia coli CFT073 1037857 NP_756280.1 CDS mtlR NC_004431.1 4203245 4203832 D Acts as a repressor of the mtlAD operon; mannitol repressor protein 4203245..4203832 Escherichia coli CFT073 1037649 NP_756281.1 CDS c4419 NC_004431.1 4203843 4204052 R Residues 1 to 67 of 69 are 77.61 pct identical to residues 1 to 67 of 69 from GenPept.129 : >gb|AAL22547.1| (AE008871) cytoplasmic protein [Salmonella typhimurium LT2]; hypothetical protein complement(4203843..4204052) Escherichia coli CFT073 1037629 NP_756282.1 CDS c4420 NC_004431.1 4204255 4204665 R hypothetical protein complement(4204255..4204665) Escherichia coli CFT073 1038090 NP_756283.1 CDS yibL NC_004431.1 4204336 4204698 D Escherichia coli K-12 ortholog: b3602; Escherichia coli O157:H7 ortholog: z5026; hypothetical protein 4204336..4204698 Escherichia coli CFT073 1038097 NP_756284.1 CDS c4422 NC_004431.1 4204954 4205121 R hypothetical protein complement(4204954..4205121) Escherichia coli CFT073 1037859 NP_756285.1 CDS c4423 NC_004431.1 4205257 4205940 D Escherichia coli O157:H7 ortholog: z5028; hypothetical protein 4205257..4205940 Escherichia coli CFT073 1037688 NP_756286.1 CDS c4424 NC_004431.1 4205984 4211320 D Escherichia coli O157:H7 ortholog: z5029; adhesin 4205984..4211320 Escherichia coli CFT073 1038067 NP_756287.1 CDS lldP NC_004431.1 4211711 4213387 D Escherichia coli K-12 ortholog: b3603; Escherichia coli O157:H7 ortholog: z5030; L-lactate permease 4211711..4213387 Escherichia coli CFT073 1037724 NP_756288.1 CDS lldR NC_004431.1 4213372 4214163 D represses the lctPRD operon; DNA-binding transcriptional repressor LldR 4213372..4214163 Escherichia coli CFT073 1038127 NP_756289.1 CDS lldD NC_004431.1 4214160 4215350 D flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 4214160..4215350 Escherichia coli CFT073 1038129 NP_756290.1 CDS yibK NC_004431.1 4215398 4215871 D member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; tRNA/rRNA methyltransferase YibK 4215398..4215871 Escherichia coli CFT073 1038081 NP_756291.1 CDS cysE NC_004431.1 4215926 4216747 R catalyzes the O-acetylation of serine; serine acetyltransferase complement(4215926..4216747) Escherichia coli CFT073 1037917 NP_756292.1 CDS gpsA NC_004431.1 4216827 4217846 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(4216827..4217846) Escherichia coli CFT073 1038114 NP_756293.1 CDS c4431 NC_004431.1 4217825 4218310 D Residues 12 to 161 of 161 are 95.33 pct identical to residues 1 to 150 of 150 from SwissProt.40 : >sp|P15041|YZSB_ECOLI VERY HYPOTHETICAL 17.7 KD PROTEIN IN SECB REGION; hypothetical protein 4217825..4218310 Escherichia coli CFT073 1038087 NP_756294.2 CDS secB NC_004431.1 4217846 4218313 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB complement(4217846..4218313) Escherichia coli CFT073 1037860 NP_756295.1 CDS grxC NC_004431.1 4218377 4218628 R Grx3; Escherichia coli K-12 ortholog: b3610; Escherichia coli O157:H7 ortholog: z5037; glutaredoxin 3 complement(4218377..4218628) Escherichia coli CFT073 1038120 NP_756296.1 CDS c4434 NC_004431.1 4218443 4218706 D hypothetical protein 4218443..4218706 Escherichia coli CFT073 1038155 NP_756297.1 CDS c4435 NC_004431.1 4218725 4218883 R hypothetical protein complement(4218725..4218883) Escherichia coli CFT073 1038118 NP_756298.1 CDS yibN NC_004431.1 4218769 4219212 R Escherichia coli K-12 ortholog: b3611; Escherichia coli O157:H7 ortholog: z5038; hypothetical protein complement(4218769..4219212) Escherichia coli CFT073 1038088 NP_756299.1 CDS c4437 NC_004431.1 4219224 4219421 D hypothetical protein 4219224..4219421 Escherichia coli CFT073 1038178 NP_756300.2 CDS yibO NC_004431.1 4219445 4220989 D catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 4219445..4220989 Escherichia coli CFT073 1038126 NP_756301.1 CDS yibP NC_004431.1 4220999 4222282 D Escherichia coli K-12 ortholog: b3613; Escherichia coli O157:H7 ortholog: z5040; hypothetical protein 4220999..4222282 Escherichia coli CFT073 1038123 NP_756302.1 CDS yibQ NC_004431.1 4222286 4223245 D Escherichia coli K-12 ortholog: b3614; Escherichia coli O157:H7 ortholog: z5041; hypothetical protein 4222286..4223245 Escherichia coli CFT073 1038084 NP_756303.1 CDS yibD NC_004431.1 4223232 4224266 R Escherichia coli K-12 ortholog: b3615; Escherichia coli O157:H7 ortholog: z5042; glycosyl transferase complement(4223232..4224266) Escherichia coli CFT073 1038154 NP_756304.1 CDS c4442 NC_004431.1 4224496 4225521 D hypothetical protein 4224496..4225521 Escherichia coli CFT073 1038208 NP_756305.1 CDS tdh NC_004431.1 4224505 4225530 R converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase complement(4224505..4225530) Escherichia coli CFT073 1038233 NP_756306.1 CDS kbl NC_004431.1 4225540 4226736 R catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate CoA ligase complement(4225540..4226736) Escherichia coli CFT073 1038222 NP_756307.1 CDS rfaD NC_004431.1 4226950 4227882 D catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 4226950..4227882 Escherichia coli CFT073 1038172 NP_756308.1 CDS rfaF NC_004431.1 4227892 4228938 D catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose:LPS heptosyltransferase II 4227892..4228938 Escherichia coli CFT073 1038150 NP_756309.1 CDS rfaC NC_004431.1 4228942 4229922 D Escherichia coli K-12 ortholog: b3621; Escherichia coli O157:H7 ortholog: z5048; ADP-heptose:LPS heptosyl transferase I 4228942..4229922 Escherichia coli CFT073 1038145 NP_756310.1 CDS waaL NC_004431.1 4229992 4231245 R Residues 1 to 417 of 417 are 96.40 pct identical to residues 1 to 417 of 417 from GenPept.129 : >gb|AAC69671.1| (AF019746) lipid A-core:surface polymer ligase WaaL [Escherichia coli]; Lipid A-core, surface polymer ligase complement(4229992..4231245) Escherichia coli CFT073 1038237 NP_756311.1 CDS waaV NC_004431.1 4231291 4232274 R Residues 1 to 327 of 327 are 96.63 pct identical to residues 1 to 327 of 327 from GenPept.129 : >gb|AAC69672.1| (AF019746) beta1,3-glucosyltransferase WaaV [Escherichia coli]; beta1,3-glucosyltransferase complement(4231291..4232274) Escherichia coli CFT073 1038238 NP_756312.1 CDS waaW NC_004431.1 4232356 4233384 R Residues 1 to 341 of 342 are 98.24 pct identical to residues 1 to 341 of 341 from GenPept.129 : >gb|AAC69673.1| (AF019746) UDP-galactose:(galactosyl) LPS alpha1,2-galactosyltransferase WaaW [Escherichia coli]; UDP-galactose:(galactosyl) LPS alpha1,2-galactosyltransferase complement(4232356..4233384) Escherichia coli CFT073 1038245 NP_756313.1 CDS rfaY NC_004431.1 4233410 4234102 R Escherichia coli K-12 ortholog: b3625; Escherichia coli O157:H7 ortholog: z5052; lipopolysaccharide core biosynthesis protein complement(4233410..4234102) Escherichia coli CFT073 1038241 NP_756314.1 CDS rfaJ NC_004431.1 4234112 4235107 R Escherichia coli K-12 ortholog: b3626; Escherichia coli O157:H7 ortholog: z5051; lipopolysaccharide 1,2-glucosyltransferase complement(4234112..4235107) Escherichia coli CFT073 1038224 NP_756315.1 CDS rfaI NC_004431.1 4235124 4236140 R Escherichia coli K-12 ortholog: b3627; Escherichia coli O157:H7 ortholog: z5053; lipopolysaccharide 1,3-galactosyltransferase complement(4235124..4236140) Escherichia coli CFT073 1038256 NP_756316.1 CDS rfaP NC_004431.1 4236156 4236962 R Escherichia coli K-12 ortholog: b3630; Escherichia coli O157:H7 ortholog: z5054; lipopolysaccharide core biosynthesis protein rfaP complement(4236156..4236962) Escherichia coli CFT073 1038179 NP_756317.1 CDS rfaG NC_004431.1 4236946 4238070 R Glucosyltransferase I; Escherichia coli K-12 ortholog: b3631; Escherichia coli O157:H7 ortholog: z5055; lipopolysaccharide core biosynthesis protein rfaG complement(4236946..4238070) Escherichia coli CFT073 1038213 NP_756318.1 CDS rfaQ NC_004431.1 4238067 4239125 R Escherichia coli K-12 ortholog: b3632; Escherichia coli O157:H7 ortholog: z5056; lipopolysaccharide core biosynthesis protein complement(4238067..4239125) Escherichia coli CFT073 1038250 NP_756319.1 CDS kdtA NC_004431.1 4239538 4240815 D catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 4239538..4240815 Escherichia coli CFT073 1038246 NP_756320.1 CDS coaD NC_004431.1 4240823 4241302 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 4240823..4241302 Escherichia coli CFT073 1038251 NP_756321.1 CDS mutM NC_004431.1 4241341 4242150 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(4241341..4242150) Escherichia coli CFT073 1038243 NP_756322.1 CDS rpmG NC_004431.1 4242248 4242415 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(4242248..4242415) Escherichia coli CFT073 1038249 NP_756323.1 CDS rpmB NC_004431.1 4242436 4242672 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(4242436..4242672) Escherichia coli CFT073 1038253 NP_756324.1 CDS radC NC_004431.1 4242889 4243563 R Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC complement(4242889..4243563) Escherichia coli CFT073 1038232 NP_756325.2 CDS dfp NC_004431.1 4243729 4244949 D catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 4243729..4244949 Escherichia coli CFT073 1038234 NP_756326.1 CDS dut NC_004431.1 4244927 4245385 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 4244927..4245385 Escherichia coli CFT073 1038261 NP_756327.2 CDS slmA NC_004431.1 4245492 4246088 D FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 4245492..4246088 Escherichia coli CFT073 1038257 NP_756328.2 CDS pyrE NC_004431.1 4246125 4246766 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(4246125..4246766) Escherichia coli CFT073 1038255 NP_756329.2 CDS rph NC_004431.1 4246832 4247548 R RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH complement(4246832..4247548) Escherichia coli CFT073 1038263 NP_756330.1 CDS yicC NC_004431.1 4247675 4248538 D Escherichia coli K-12 ortholog: b3644; Escherichia coli O157:H7 ortholog: z5069; hypothetical protein 4247675..4248538 Escherichia coli CFT073 1038260 NP_756331.2 CDS dinD NC_004431.1 4248760 4249584 D Escherichia coli K-12 ortholog: b3645; Escherichia coli O157:H7 ortholog: z5070; DNA-damage-inducible protein D 4248760..4249584 Escherichia coli CFT073 1038284 NP_756332.1 CDS yicG NC_004431.1 4249822 4250493 D Escherichia coli K-12 ortholog: b3646; Escherichia coli O157:H7 ortholog: z5071; hypothetical protein 4249822..4250493 Escherichia coli CFT073 1038270 NP_756333.1 CDS ligB NC_004431.1 4250490 4252178 R this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB complement(4250490..4252178) Escherichia coli CFT073 1038244 NP_756334.1 CDS c4472 NC_004431.1 4252033 4252296 R hypothetical protein complement(4252033..4252296) Escherichia coli CFT073 1038268 NP_756335.2 CDS gmk NC_004431.1 4252430 4253053 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 4252430..4253053 Escherichia coli CFT073 1038453 NP_756336.1 CDS rpoZ NC_004431.1 4253108 4253383 D promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 4253108..4253383 Escherichia coli CFT073 1038274 NP_756337.1 CDS spoT NC_004431.1 4253402 4255510 D Escherichia coli K-12 ortholog: b3650; Escherichia coli O157:H7 ortholog: z5076; bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 4253402..4255510 Escherichia coli CFT073 1038278 NP_756338.1 CDS spoU NC_004431.1 4255517 4256206 D specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 4255517..4256206 Escherichia coli CFT073 1038271 NP_756339.2 CDS recG NC_004431.1 4256212 4258293 D catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 4256212..4258293 Escherichia coli CFT073 1038359 NP_756340.1 CDS gltS NC_004431.1 4258327 4259532 R Glutamate permease; Escherichia coli K-12 ortholog: b3653; Escherichia coli O157:H7 ortholog: z5081; Sodium/glutamate symport carrier protein complement(4258327..4259532) Escherichia coli CFT073 1038264 NP_756341.1 CDS yicE NC_004431.1 4259803 4261203 D Escherichia coli K-12 ortholog: b3654; Escherichia coli O157:H7 ortholog: z5082; purine permease yicE 4259803..4261203 Escherichia coli CFT073 1038310 NP_756342.1 CDS yicH NC_004431.1 4261300 4263033 D Escherichia coli K-12 ortholog: b3655; Escherichia coli O157:H7 ortholog: z5083; hypothetical protein 4261300..4263033 Escherichia coli CFT073 1038512 NP_756343.1 CDS c4481 NC_004431.1 4263077 4263796 R Escherichia coli O157:H7 ortholog: z5688; hypothetical protein complement(4263077..4263796) Escherichia coli CFT073 1038517 NP_756344.1 CDS c4482 NC_004431.1 4263738 4264703 R Escherichia coli K-12 ortholog: b0394; Escherichia coli O157:H7 ortholog: z0493; hypothetical protein complement(4263738..4264703) Escherichia coli CFT073 1038368 NP_756345.1 CDS c4483 NC_004431.1 4264718 4265578 R Escherichia coli O157:H7 ortholog: z5687; hypothetical protein complement(4264718..4265578) Escherichia coli CFT073 1038321 NP_756346.1 CDS c4484 NC_004431.1 4265659 4266510 R Residues 1 to 283 of 283 are 39.78 pct identical to residues 1 to 283 of 284 from GenPept.129 : >emb|CAD00212.1| (AL591982) similar to fructose-1,6-biphosphate aldolase type II [Listeria monocytogenes]; aldolase complement(4265659..4266510) Escherichia coli CFT073 1038302 NP_756347.1 CDS c4485 NC_004431.1 4266522 4267613 R Residues 11 to 358 of 363 are 53.10 pct identical to residues 5 to 355 of 363 from GenPept.129 : >emb|CAC97469.1| (AL596171) similar to PTS system, fructose-specific enzyme IIC component [Listeria innocua]; PTS enzyme-II fructose complement(4266522..4267613) Escherichia coli CFT073 1038496 NP_756348.1 CDS c4486 NC_004431.1 4267638 4267952 R Phosphotransferase enzyme II, B component; Escherichia coli K-12 ortholog: b3950; Escherichia coli O157:H7 ortholog: z5506; PTS system, fructose-like-2 IIB component 1 complement(4267638..4267952) Escherichia coli CFT073 1038289 NP_756349.1 CDS c4487 NC_004431.1 4267970 4268440 R Residues 1 to 149 of 156 are 48.32 pct identical to residues 6 to 154 of 157 from GenPept.129 : >emb|CAC97471.1| (AL596171) similar to PTS system, fructose-specific enzyme IIA component [Listeria innocua]; phosphotransferase system (PTS), fructose-specific complement(4267970..4268440) Escherichia coli CFT073 1038406 NP_756350.1 CDS c4488 NC_004431.1 4268467 4270065 R Residues 18 to 515 of 532 are 28.32 pct identical to residues 2 to 483 of 485 from GenPept.129 : >emb|CAD00216.1| (AL591982) similar to transcription regulator [Listeria monocytogenes]; transcriptional antiterminator complement(4268467..4270065) Escherichia coli CFT073 1038572 NP_756351.1 CDS yicI NC_004431.1 4270305 4272623 R catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase YicI complement(4270305..4272623) Escherichia coli CFT073 1038574 NP_756352.2 CDS yicJ NC_004431.1 4272633 4274015 R may be involved in the transport of galactosides-pentoses-hexuronides; transporter complement(4272633..4274015) Escherichia coli CFT073 1038482 NP_756353.1 CDS intC NC_004431.1 4274702 4275886 D Escherichia coli K-12 ortholog: b2349; Escherichia coli O157:H7 ortholog: z5087; prophage integrase 4274702..4275886 Escherichia coli CFT073 1038554 NP_756354.1 CDS c4492 NC_004431.1 4276297 4277340 D Residues 1 to 347 of 347 are 96.82 pct identical to residues 1 to 347 of 347 from GenPept.129 : >gb|AAD44731.1|AF141323_2 (AF141323) ShiA [Shigella flexneri]; ShiA-like protein 4276297..4277340 Escherichia coli CFT073 1038476 NP_756355.1 CDS c4493 NC_004431.1 4277483 4277713 D hypothetical protein 4277483..4277713 Escherichia coli CFT073 1038422 NP_756356.1 CDS c4494 NC_004431.1 4277738 4278832 R Residues 9 to 364 of 364 are 54.03 pct identical to residues 1 to 359 of 360 from GenPept.129 : >emb|CAC89693.1| (AJ414145) LacI-family regulatory protein [Yersinia pestis]; transcriptional regulator complement(4277738..4278832) Escherichia coli CFT073 1038682 NP_756357.1 CDS c4495 NC_004431.1 4279013 4280371 D Escherichia coli K-12 ortholog: b3093; Escherichia coli O157:H7 ortholog: z4446; hexuronate transporter 4279013..4280371 Escherichia coli CFT073 1038562 NP_756358.1 CDS c4496 NC_004431.1 4280380 4281033 D Residues 3 to 213 of 217 are 62.08 pct identical to residues 2 to 212 of 792 from GenPept.129 : >emb|CAC89695.1| (AJ414145) glucosidase [Yersinia pestis]; glucosidase 4280380..4281033 Escherichia coli CFT073 1038555 NP_756359.1 CDS c4497 NC_004431.1 4280984 4282768 D Residues 13 to 581 of 594 are 74.86 pct identical to residues 213 to 781 of 792 from GenPept.129 : >emb|CAC89695.1| (AJ414145) glucosidase [Yersinia pestis]; glucosidase 4280984..4282768 Escherichia coli CFT073 1038509 NP_756360.1 CDS c4498 NC_004431.1 4283544 4283861 R Escherichia coli O157:H7 ortholog: z1632; IS1 protein InsB complement(4283544..4283861) Escherichia coli CFT073 1038666 NP_756361.1 CDS c4499 NC_004431.1 4283872 4284084 R Residues 1 to 69 of 70 are 98.55 pct identical to residues 1 to 69 of 70 from GenPept.129 : >gb|AAK18551.1|AF348706_240 (AF348706) iso-IS1 orf [Shigella flexneri]; hypothetical protein complement(4283872..4284084) Escherichia coli CFT073 1038567 NP_756362.1 CDS c4500 NC_004431.1 4284198 4285697 R Residues 20 to 492 of 499 are 47.78 pct identical to residues 12 to 476 of 483 from GenPept.129 : >gb|AAF73583.1| (AE002332) amino acid permease [Chlamydia muridarum]; amino acid antiporter complement(4284198..4285697) Escherichia coli CFT073 1038489 NP_756363.1 CDS c4501 NC_004431.1 4285772 4288141 R Residues 7 to 750 of 789 are 38.82 pct identical to residues 4 to 744 of 756 from MG1655 : b4117; hypothetical protein complement(4285772..4288141) Escherichia coli CFT073 1038739 NP_756364.1 CDS c4502 NC_004431.1 4288246 4289715 R Residues 5 to 481 of 489 are 50.10 pct identical to residues 2 to 479 of 485 from GenPept.129 : >gb|AAD19168.1| (AE001683) Arginine/Ornithine Antiporter [Chlamydophila pneumoniae CWL029]; antiporter complement(4288246..4289715) Escherichia coli CFT073 1038757 NP_756365.1 CDS c4503 NC_004431.1 4289968 4290240 D IS1a/IS1b/IS1c/IS1d; Escherichia coli K-12 ortholog: b3444; insertion element IS1 1/2/3/5/6 protein insA 4289968..4290240 Escherichia coli CFT073 1038568 NP_756366.1 CDS insB NC_004431.1 4290267 4290626 D Escherichia coli K-12 ortholog: b3445; Escherichia coli O157:H7 ortholog: z1562; insertion element IS1 1/5/6 protein insB 4290267..4290626 Escherichia coli CFT073 1038809 NP_756367.1 CDS c4505 NC_004431.1 4291249 4291626 D Residues 13 to 125 of 125 are 62.83 pct identical to residues 2 to 114 of 324 from GenPept.129 : >gb|AAL22245.1| (AE008855) oxidoreductase [Salmonella typhimurium LT2]; hypothetical protein 4291249..4291626 Escherichia coli CFT073 1038694 NP_756368.1 CDS insI NC_004431.1 4291966 4293117 R Escherichia coli K-12 ortholog: b4284; Escherichia coli O157:H7 ortholog: z2993; transposase insI complement(4291966..4293117) Escherichia coli CFT073 1038625 NP_756369.1 CDS c4507 NC_004431.1 4293266 4294078 D Escherichia coli K-12 ortholog: b2089; transposase insF 4293266..4294078 Escherichia coli CFT073 1038813 NP_756370.1 CDS c4508 NC_004431.1 4294099 4294284 D Residues 1 to 61 of 61 are 98.36 pct identical to residues 477 to 537 of 537 from GenPept.129 : >gb|AAG55715.1|AE005309_5 (AE005309) unknown in ISEc8 [Escherichia coli O157:H7 EDL933]; hypothetical protein 4294099..4294284 Escherichia coli CFT073 1038908 NP_756371.1 CDS c4509 NC_004431.1 4294419 4295747 D Residues 379 to 441 of 442 are 49.20 pct identical to residues 20 to 80 of 90 from GenPept.129 : >gb|AAK99647.1| (AE008459) Hypothetical protein [Streptococcus pneumoniae R6]; hypothetical protein 4294419..4295747 Escherichia coli CFT073 1038856 NP_756372.1 CDS c4510 NC_004431.1 4295755 4296330 D hypothetical protein 4295755..4296330 Escherichia coli CFT073 1038662 NP_756373.1 CDS c4511 NC_004431.1 4296883 4297608 R Residues 3 to 238 of 241 are 48.73 pct identical to residues 2 to 239 of 256 from GenPept.129 : >gb|AAL45712.1| (AE008927) conserved hypothetical protein [Agrobacterium tumefaciens str. C58 (U. Washington)]; hypothetical protein complement(4296883..4297608) Escherichia coli CFT073 1038723 NP_756374.1 CDS c4512 NC_004431.1 4297605 4298924 R Residues 30 to 392 of 439 are 40.10 pct identical to residues 20 to 375 of 423 from GenPept.129 : >gb|AAF12682.1|AE001827_20 (AE001827) hypothetical protein [Deinococcus radiodurans]; hypothetical protein complement(4297605..4298924) Escherichia coli CFT073 1039045 NP_756375.1 CDS c4513 NC_004431.1 4298906 4299658 R Residues 1 to 190 of 250 are 29.41 pct identical to residues 1 to 236 of 298 from GenPept.129 : >gb|AAL45714.1| (AE008927) conserved hypothetical protein [Agrobacterium tumefaciens str. C58 (U. Washington)]; hypothetical protein complement(4298906..4299658) Escherichia coli CFT073 1039072 NP_756376.1 CDS c4514 NC_004431.1 4299658 4301442 R Residues 1 to 594 of 594 are 33.00 pct identical to residues 1 to 606 of 632 from GenPept.129 : >gb|AAL45715.1| (AE008927) conserved hypothetical protein [Agrobacterium tumefaciens str. C58 (U. Washington)]; hypothetical protein complement(4299658..4301442) Escherichia coli CFT073 1039077 NP_756377.1 CDS c4517 NC_004431.1 4303106 4303504 R Residues 1 to 120 of 132 are 39.34 pct identical to residues 324 to 445 of 455 from GenPept.129 : >emb|CAC90312.1| (AJ414148) hypothetical protein [Yersinia pestis]; hypothetical protein complement(4303106..4303504) Escherichia coli CFT073 1038792 NP_756378.1 CDS c4518 NC_004431.1 4303576 4304013 R Residues 30 to 145 of 145 are 97.41 pct identical to residues 1 to 116 of 348 from GenPept.129 : >gb|AAG55755.1|AE005312_1 (AE005312) Z1640 gene product [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(4303576..4304013) Escherichia coli CFT073 1038896 NP_756379.1 CDS c4519 NC_004431.1 4304030 4304158 R hypothetical protein complement(4304030..4304158) Escherichia coli CFT073 1038879 NP_756380.1 CDS c4520 NC_004431.1 4304606 4304797 D Escherichia coli O157:H7 ortholog: z1637; hypothetical protein 4304606..4304797 Escherichia coli CFT073 1039116 NP_756381.1 CDS c4521 NC_004431.1 4304850 4305158 R Escherichia coli O157:H7 ortholog: z1636; hypothetical protein complement(4304850..4305158) Escherichia coli CFT073 1039122 NP_756382.1 CDS c4522 NC_004431.1 4305133 4305537 D hypothetical protein 4305133..4305537 Escherichia coli CFT073 1039102 NP_756383.1 CDS c4523 NC_004431.1 4305179 4305580 R Escherichia coli O157:H7 ortholog: z1635; hypothetical protein complement(4305179..4305580) Escherichia coli CFT073 1039125 NP_756384.1 CDS c4524 NC_004431.1 4306029 4307147 D Residues 10 to 370 of 372 are 44.41 pct identical to residues 9 to 375 of 376 from GenPept.129 : >dbj|BAB80598.1| (AP003188) NADPH-dependent butanol dehydrogenase [Clostridium perfringens]; propanol dehydrogenase 4306029..4307147 Escherichia coli CFT073 1039127 NP_756385.1 CDS c4525 NC_004431.1 4307287 4307973 D Residues 37 to 218 of 228 are 54.64 pct identical to residues 23 to 205 of 210 from GenPept.129 : >gb|AAD35462.1|AE001717_8 (AE001717) hypothetical protein [Thermotoga maritima]; chormophorylate of CpcA 4307287..4307973 Escherichia coli CFT073 1039082 NP_756386.1 CDS c4526 NC_004431.1 4308028 4308786 D Escherichia coli K-12 ortholog: b2454; Escherichia coli O157:H7 ortholog: z3710; ethanolamine utilization protein EutJ 4308028..4308786 Escherichia coli CFT073 1039373 NP_756387.1 CDS c4527 NC_004431.1 4308770 4309495 D hypothetical protein 4308770..4309495 Escherichia coli CFT073 1039069 NP_756388.1 CDS c4528 NC_004431.1 4309507 4309776 D Escherichia coli K-12 ortholog: b2456; Escherichia coli O157:H7 ortholog: z3712; ethanolamine utilization protein EutN 4309507..4309776 Escherichia coli CFT073 1039076 NP_756389.1 CDS c4529 NC_004431.1 4309804 4310301 D Residues 25 to 156 of 165 are 50.00 pct identical to residues 199 to 332 of 336 from GenPept.129 : >gb|AAL20954.1| (AE008790) Propanediol utilization: B12 related [Salmonella typhimurium LT2]; hypothetical protein 4309804..4310301 Escherichia coli CFT073 1039428 NP_756390.1 CDS tdcD NC_004431.1 4310306 4311526 D catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase 4310306..4311526 Escherichia coli CFT073 1039144 NP_756391.1 CDS c4531 NC_004431.1 4310426 4310605 R hypothetical protein complement(4310426..4310605) Escherichia coli CFT073 1039224 NP_756392.1 CDS c4532 NC_004431.1 4311760 4312011 D Residues 18 to 67 of 83 are 89.99 pct identical to residues 1 to 50 of 94 from GenPept.129 : >gb|AAL20942.1| (AE008790) Propanediol utilization: polyhedral bodies [Salmonella typhimurium LT2]; hypothetical protein 4311760..4312011 Escherichia coli CFT073 1039250 NP_756393.1 CDS c4533 NC_004431.1 4312116 4312901 D Residues 33 to 261 of 261 are 63.31 pct identical to residues 6 to 233 of 233 from SwissProt.40 : >sp|P37449|PDUB_SALTY PROPANEDIOL UTILIZATION PROTEIN PDUB; pduB protein 4312116..4312901 Escherichia coli CFT073 1039148 NP_756394.1 CDS c4534 NC_004431.1 4312962 4314479 D Escherichia coli K-12 ortholog: b2455; Escherichia coli O157:H7 ortholog: z3711; ethanolamine utilization protein EutE 4312962..4314479 Escherichia coli CFT073 1039466 NP_756395.1 CDS c4535 NC_004431.1 4314503 4314802 D hypothetical protein 4314503..4314802 Escherichia coli CFT073 1039132 NP_756396.1 CDS c4536 NC_004431.1 4314777 4315388 D Residues 14 to 198 of 203 are 56.75 pct identical to residues 3 to 187 of 188 from GenPept.129 : >gb|AAL45236.1| (AE009373) conserved hypothetical protein [Agrobacterium tumefaciens str. C58 (U. Washington)]; hypothetical protein 4314777..4315388 Escherichia coli CFT073 1039097 NP_756397.1 CDS c4537 NC_004431.1 4315437 4317989 D Residues 10 to 849 of 850 are 34.39 pct identical to residues 2 to 765 of 765 from MG1655 : b3951; hypothetical protein 4315437..4317989 Escherichia coli CFT073 1039560 NP_756398.1 CDS c4538 NC_004431.1 4318098 4319015 D Escherichia coli K-12 ortholog: b0824; Escherichia coli O157:H7 ortholog: z1047; pyruvate formate-lyase 3 activating enzyme 4318098..4319015 Escherichia coli CFT073 1039446 NP_756399.1 CDS c4539 NC_004431.1 4319152 4320057 D Residues 6 to 294 of 301 are 32.72 pct identical to residues 23 to 340 of 349 from GenPept.129 : >gb|AAG20144.1| (AE005092) Vng1965h [Halobacterium sp. NRC-1]; hypothetical protein 4319152..4320057 Escherichia coli CFT073 1039531 NP_756400.1 CDS c4540 NC_004431.1 4320543 4321082 D Residues 47 to 179 of 179 are 43.82 pct identical to residues 2 to 163 of 418 from GenPept.129 : >dbj|BAB04330.1| (AP001509) transposase (11) [Bacillus halodurans]; maturase-related protein 4320543..4321082 Escherichia coli CFT073 1039533 NP_756401.1 CDS c4541 NC_004431.1 4321110 4321631 D Residues 1 to 173 of 173 are 50.85 pct identical to residues 228 to 402 of 490 from GenPept.129 : >gb|AAB68949.1| (U77945) maturase-related protein [Pseudomonas alcaligenes]; maturase-related protein 4321110..4321631 Escherichia coli CFT073 1039477 NP_756402.1 CDS c4542 NC_004431.1 4321370 4321690 D hypothetical protein 4321370..4321690 Escherichia coli CFT073 1039559 NP_756403.1 CDS c4543 NC_004431.1 4321940 4322074 D hypothetical protein 4321940..4322074 Escherichia coli CFT073 1039595 NP_756404.1 CDS c4544 NC_004431.1 4321953 4322141 D hypothetical protein 4321953..4322141 Escherichia coli CFT073 1039584 NP_756405.1 CDS c4545 NC_004431.1 4322181 4323443 D Residues 12 to 416 of 420 are 34.38 pct identical to residues 1 to 407 of 410 from GenPept.129 : >dbj|BAB80633.1| (AP003188) two-component sensor histidine kinase [Clostridium perfringens]; hypothetical protein 4322181..4323443 Escherichia coli CFT073 1039627 NP_756406.1 CDS c4546 NC_004431.1 4323460 4324515 D Residues 245 to 342 of 351 are 45.91 pct identical to residues 178 to 275 of 317 from GenPept.129 : >emb|CAD01088.1| (AJ297723) transcriptional regulator [Lactobacillus collinoides]; hypothetical protein 4323460..4324515 Escherichia coli CFT073 1039575 NP_756407.1 CDS c4547 NC_004431.1 4324644 4325795 D methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 4324644..4325795 Escherichia coli CFT073 1039628 NP_756408.1 CDS c4548 NC_004431.1 4325744 4326385 D Residues 37 to 121 of 213 are 55.29 pct identical to residues 6 to 89 of 94 from GenPept.129 : >gb|AAL94296.1| (AE010523) Ethanolamine utilization protein eutM precursor [Fusobacterium nucleatum subsp. nucleatum ATCC 25586]; hypothetical protein 4325744..4326385 Escherichia coli CFT073 1039624 NP_756409.1 CDS c4549 NC_004431.1 4326878 4327087 R Residues 11 to 60 of 69 are 47.99 pct identical to residues 7 to 56 of 107 from GenPept.129 : >gb|AAL23089.1| (AE008900) transcriptional activator of superoxide response regulon (AraC/XylS family) [Salmonella typhimurium LT2]; hypothetical protein complement(4326878..4327087) Escherichia coli CFT073 1039626 NP_756410.1 CDS c4550 NC_004431.1 4327162 4327731 R Residues 9 to 178 of 189 are 29.31 pct identical to residues 1 to 174 of 212 from GenPept.129 : >gb|AAG06962.1|AE004778_6 (AE004778) probable transcriptional regulator [Pseudomonas aeruginosa]; hypothetical protein complement(4327162..4327731) Escherichia coli CFT073 1039630 NP_756411.1 CDS c4551 NC_004431.1 4327831 4328895 R Residues 33 to 328 of 354 are 21.82 pct identical to residues 185 to 490 of 1046 from GenPept.129 : >gb|AAG03815.1|AE004479_10 (AE004479) RND multidrug efflux transporter MexB [Pseudomonas aeruginosa]; hypothetical protein complement(4327831..4328895) Escherichia coli CFT073 1039629 NP_756412.1 CDS c4552 NC_004431.1 4329034 4329369 D Escherichia coli K-12 ortholog: b4272; transposase insC 4329034..4329369 Escherichia coli CFT073 1039633 YP_004853833.1 CDS c4553 NC_004431.1 4329417 4329608 D hypothetical protein 4329417..4329608 Escherichia coli CFT073 1039656 YP_004853834.1 CDS c4554 NC_004431.1 4329427 4329759 R hypothetical protein complement(4329427..4329759) Escherichia coli CFT073 1039637 YP_004853835.1 CDS c4555 NC_004431.1 4329522 4329647 R hypothetical protein complement(4329522..4329647) Escherichia coli CFT073 1039638 NP_756416.1 CDS c4556 NC_004431.1 4329644 4329877 R Escherichia coli O157:H7 ortholog: z1627; hypothetical protein complement(4329644..4329877) Escherichia coli CFT073 1039635 NP_756417.1 CDS c4557 NC_004431.1 4329946 4330710 R Residues 104 to 248 of 254 are 88.27 pct identical to residues 30 to 174 of 179 from GenPept.129 : >gb|AAL67421.1|AF447814_89 (AF447814) unknown [Escherichia coli]; hypothetical protein complement(4329946..4330710) Escherichia coli CFT073 1039649 NP_756418.1 CDS c4558 NC_004431.1 4330868 4331599 R Residues 1 to 243 of 243 are 85.59 pct identical to residues 1 to 243 of 246 from GenPept.129 : >gb|AAL67401.1|AF447814_69 (AF447814) intergenic-region protein [Escherichia coli]; hypothetical protein complement(4330868..4331599) Escherichia coli CFT073 1039640 NP_756419.1 CDS c4559 NC_004431.1 4331010 4331156 D hypothetical protein 4331010..4331156 Escherichia coli CFT073 1039639 NP_756420.1 CDS c4560 NC_004431.1 4331703 4331861 D hypothetical protein 4331703..4331861 Escherichia coli CFT073 1039665 NP_756421.1 CDS c4561 NC_004431.1 4333119 4334249 R hypothetical protein complement(4333119..4334249) Escherichia coli CFT073 1039666 NP_756424.1 CDS c4564 NC_004431.1 4334434 4335318 D Residues 1 to 294 of 294 are 94.55 pct identical to residues 1 to 294 of 294 from GenPept.129 : >gb|AAL67395.1|AF447814_63 (AF447814) unknown [Escherichia coli]; hypothetical protein 4334434..4335318 Escherichia coli CFT073 1039643 NP_756425.1 CDS c4565 NC_004431.1 4335337 4335492 D hypothetical protein 4335337..4335492 Escherichia coli CFT073 1039661 NP_756426.1 CDS c4566 NC_004431.1 4335521 4336201 D Escherichia coli K-12 ortholog: b2634; transcriptional regulator YfjR 4335521..4336201 Escherichia coli CFT073 1039641 NP_756427.1 CDS c4567 NC_004431.1 4336085 4336216 R hypothetical protein complement(4336085..4336216) Escherichia coli CFT073 1039651 NP_756428.1 CDS c4568 NC_004431.1 4336244 4337026 D Residues 1 to 161 of 260 are 99.37 pct identical to residues 1 to 161 of 260 from GenPept.129 : >gb|AAL67392.1|AF447814_60 (AF447814) intergenic-region protein [Escherichia coli]; hypothetical protein 4336244..4337026 Escherichia coli CFT073 1039645 NP_756429.1 CDS c4569 NC_004431.1 4337032 4337265 D Escherichia coli K-12 ortholog: b0249; hypothetical protein 4337032..4337265 Escherichia coli CFT073 1039655 NP_756430.1 CDS c4570 NC_004431.1 4337355 4338173 D Escherichia coli K-12 ortholog: b0252; Escherichia coli O157:H7 ortholog: z1655; hypothetical protein 4337355..4338173 Escherichia coli CFT073 1039657 NP_756431.1 CDS c4571 NC_004431.1 4338265 4338750 D Escherichia coli K-12 ortholog: b2643; Escherichia coli O157:H7 ortholog: z1656; hypothetical protein 4338265..4338750 Escherichia coli CFT073 1039663 NP_756432.1 CDS c4572 NC_004431.1 4338319 4338765 R Residues 6 to 143 of 148 are 85.50 pct identical to residues 161 to 298 of 319 from GenPept.129 : >gb|AAL67347.1|AF447814_15 (AF447814) unknown [Escherichia coli]; hypothetical protein complement(4338319..4338765) Escherichia coli CFT073 1039662 NP_756433.1 CDS c4573 NC_004431.1 4338795 4339241 D Escherichia coli K-12 ortholog: b2002; Escherichia coli O157:H7 ortholog: z1217; radC-like protein yeeS 4338795..4339241 Escherichia coli CFT073 1039660 NP_756434.1 CDS c4574 NC_004431.1 4339304 4339525 D Escherichia coli K-12 ortholog: b2003; Escherichia coli O157:H7 ortholog: z1218; hypothetical protein 4339304..4339525 Escherichia coli CFT073 1039652 NP_756435.1 CDS c4575 NC_004431.1 4339544 4339969 D Escherichia coli K-12 ortholog: b2004; Escherichia coli O157:H7 ortholog: z1658; hypothetical protein 4339544..4339969 Escherichia coli CFT073 1039670 NP_756436.1 CDS c4576 NC_004431.1 4340059 4340436 D Escherichia coli K-12 ortholog: b2005; Escherichia coli O157:H7 ortholog: z5091; hypothetical protein 4340059..4340436 Escherichia coli CFT073 1039664 NP_756437.1 CDS c4577 NC_004431.1 4340433 4340855 D Residues 79 to 140 of 140 are 98.38 pct identical to residues 4 to 65 of 65 from GenPept.129 : >gb|AAL08480.1| (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein 4340433..4340855 Escherichia coli CFT073 1039671 NP_756438.1 CDS c4578 NC_004431.1 4340940 4341782 D Escherichia coli O157:H7 ortholog: z1664; hypothetical protein 4340940..4341782 Escherichia coli CFT073 1039668 NP_756439.1 CDS c4579 NC_004431.1 4341555 4341758 R hypothetical protein complement(4341555..4341758) Escherichia coli CFT073 1039674 NP_756440.1 CDS c4580 NC_004431.1 4342016 4342237 D Residues 3 to 70 of 73 are 41.24 pct identical to residues 148 to 227 of 327 from GenPept.129 : >emb|CAD03240.1| (AL627280) DNA-binding protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein 4342016..4342237 Escherichia coli CFT073 1039673 NP_756441.1 CDS c4581 NC_004431.1 4342378 4342875 D hypothetical protein 4342378..4342875 Escherichia coli CFT073 1039672 NP_756442.1 CDS yicL NC_004431.1 4342988 4343965 D Escherichia coli K-12 ortholog: b3660; Escherichia coli O157:H7 ortholog: z5146; transport protein YicL 4342988..4343965 Escherichia coli CFT073 1039677 NP_756443.1 CDS nlpA NC_004431.1 4343969 4344787 R Escherichia coli K-12 ortholog: b3661; Escherichia coli O157:H7 ortholog: z5147; cytoplasmic membrane lipoprotein-28 complement(4343969..4344787) Escherichia coli CFT073 1039756 NP_756444.1 CDS c4584 NC_004431.1 4344784 4344927 R hypothetical protein complement(4344784..4344927) Escherichia coli CFT073 1039688 NP_756445.1 CDS c4585 NC_004431.1 4344940 4345302 D Escherichia coli O157:H7 ortholog: z5148; hypothetical protein 4344940..4345302 Escherichia coli CFT073 1039701 NP_756446.2 CDS nepI NC_004431.1 4345343 4346533 R experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS; ribonucleoside transporter complement(4345343..4346533) Escherichia coli CFT073 1039828 NP_756447.1 CDS yicN NC_004431.1 4346744 4347223 R Escherichia coli K-12 ortholog: b3663; Escherichia coli O157:H7 ortholog: z5152; hypothetical protein complement(4346744..4347223) Escherichia coli CFT073 1039708 NP_756448.1 CDS yicO NC_004431.1 4347249 4348661 R Escherichia coli K-12 ortholog: b3664; Escherichia coli O157:H7 ortholog: z5209; hypothetical protein complement(4347249..4348661) Escherichia coli CFT073 1039800 NP_756449.1 CDS yicP NC_004431.1 4348758 4350524 D catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 4348758..4350524 Escherichia coli CFT073 1039826 NP_756450.1 CDS uhpT NC_004431.1 4350571 4351962 R cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter complement(4350571..4351962) Escherichia coli CFT073 1039821 NP_756451.1 CDS uhpC NC_004431.1 4352100 4353422 R membrane protein regulates uhpT expression; regulatory protein UhpC complement(4352100..4353422) Escherichia coli CFT073 1039717 NP_756452.1 CDS uhpB NC_004431.1 4353429 4354937 R Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB complement(4353429..4354937) Escherichia coli CFT073 1039825 NP_756453.1 CDS uhpA NC_004431.1 4354931 4355521 R response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA complement(4354931..4355521) Escherichia coli CFT073 1039847 NP_756454.1 CDS c4594 NC_004431.1 4355936 4356796 D hypothetical protein 4355936..4356796 Escherichia coli CFT073 1039675 NP_756455.1 CDS ilvN NC_004431.1 4356987 4357277 R with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit complement(4356987..4357277) Escherichia coli CFT073 1039669 NP_756456.1 CDS ilvB NC_004431.1 4357281 4358969 R catalyzes the formation of 2-acetolactate from pyruvate; acetolactate synthase catalytic subunit complement(4357281..4358969) Escherichia coli CFT073 1039852 NP_756457.1 CDS ivbL NC_004431.1 4359075 4359173 R Escherichia coli K-12 ortholog: b3672; ilvB operon leader peptide complement(4359075..4359173) Escherichia coli CFT073 1039830 NP_756458.1 CDS emrD NC_004431.1 4359568 4360758 D multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 4359568..4360758 Escherichia coli CFT073 1039829 NP_756459.1 CDS yidF NC_004431.1 4360766 4361263 R Escherichia coli K-12 ortholog: b3674; Escherichia coli O157:H7 ortholog: z5169; hypothetical protein complement(4360766..4361263) Escherichia coli CFT073 1039840 NP_756460.1 CDS yidG NC_004431.1 4361260 4361622 R Escherichia coli K-12 ortholog: b3675; Escherichia coli O157:H7 ortholog: z5170; hypothetical protein complement(4361260..4361622) Escherichia coli CFT073 1039845 NP_756461.1 CDS yidH NC_004431.1 4361612 4362019 R Escherichia coli K-12 ortholog: b3676; Escherichia coli O157:H7 ortholog: z5171; hypothetical protein complement(4361612..4362019) Escherichia coli CFT073 1039878 NP_756462.1 CDS yidJ NC_004431.1 4362019 4363512 R Escherichia coli K-12 ortholog: b3678; Escherichia coli O157:H7 ortholog: z5173; sulfatase yidJ complement(4362019..4363512) Escherichia coli CFT073 1039861 NP_756463.1 CDS yidK NC_004431.1 4363509 4365224 R uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; symporter YidK complement(4363509..4365224) Escherichia coli CFT073 1039774 NP_756464.1 CDS yidL NC_004431.1 4365361 4366257 D Escherichia coli K-12 ortholog: b3680; Escherichia coli O157:H7 ortholog: z5175; transcriptional regulator YidL 4365361..4366257 Escherichia coli CFT073 1039859 NP_756465.2 CDS yidE NC_004431.1 4366347 4368008 R ORFA; Escherichia coli K-12 ortholog: b3685; Escherichia coli O157:H7 ortholog: z5181; hypothetical protein complement(4366347..4368008) Escherichia coli CFT073 1040032 NP_756466.1 CDS c4605 NC_004431.1 4368038 4368208 D hypothetical protein 4368038..4368208 Escherichia coli CFT073 1040033 NP_756467.2 CDS ibpB NC_004431.1 4368205 4368633 R 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB complement(4368205..4368633) Escherichia coli CFT073 1039882 NP_756468.2 CDS ibpA NC_004431.1 4368745 4369158 R with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA complement(4368745..4369158) Escherichia coli CFT073 1039864 NP_756469.2 CDS yidQ NC_004431.1 4369464 4369796 D Escherichia coli K-12 ortholog: b3688; Escherichia coli O157:H7 ortholog: z5184; hypothetical protein 4369464..4369796 Escherichia coli CFT073 1039835 NP_756470.1 CDS yidR NC_004431.1 4369798 4371048 R Escherichia coli K-12 ortholog: b3689; Escherichia coli O157:H7 ortholog: z5185; hypothetical protein complement(4369798..4371048) Escherichia coli CFT073 1040021 NP_756471.1 CDS c4610 NC_004431.1 4370980 4371108 D hypothetical protein 4370980..4371108 Escherichia coli CFT073 1039850 NP_756472.2 CDS yidS NC_004431.1 4371113 4372213 D FAD/NAD(P)-binding domain; oxidoreductase 4371113..4372213 Escherichia coli CFT073 1039885 NP_756473.1 CDS dgoT NC_004431.1 4372174 4373511 R Escherichia coli K-12 ortholog: b3691; Escherichia coli O157:H7 ortholog: z4105; D-galactonate transporter complement(4372174..4373511) Escherichia coli CFT073 1040044 NP_756474.1 CDS dgoK NC_004431.1 4375333 4376211 R Escherichia coli K-12 ortholog: b3693; 2-dehydro-3-deoxygalactonokinase complement(4375333..4376211) Escherichia coli CFT073 1040027 NP_756475.1 CDS c4616 NC_004431.1 4376208 4376897 R Fusion of Escherichia coli K-12 B3694 and B3695; Residues 1 to 229 of 229 are 99.12 pct identical to residues 1 to 229 of 229 from SwissProt.40 : >sp|P31460|DGOR_ECOLI GALACTONATE OPERON TRANSCRIPTIONAL REPRESSOR; hypothetical protein complement(4376208..4376897) Escherichia coli CFT073 1039896 NP_756476.1 CDS c4617 NC_004431.1 4377158 4377649 D Residues 27 to 143 of 163 are 61.86 pct identical to residues 2 to 119 of 223 from MG1655 : b3696; hypothetical protein 4377158..4377649 Escherichia coli CFT073 1040038 NP_756477.1 CDS c4618 NC_004431.1 4377585 4377782 D Residues 6 to 42 of 65 are 62.16 pct identical to residues 250 to 286 of 325 from GenPept.129 : >gb|AAG58893.1|AE005600_11 (AE005600) replicase [Escherichia coli O157:H7 EDL933]; hypothetical protein 4377585..4377782 Escherichia coli CFT073 1039888 NP_756478.1 CDS yidA NC_004431.1 4377876 4378688 R YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase complement(4377876..4378688) Escherichia coli CFT073 1039934 NP_756479.1 CDS yidB NC_004431.1 4378803 4379210 R Escherichia coli K-12 ortholog: b3698; Escherichia coli O157:H7 ortholog: z5189; hypothetical protein complement(4378803..4379210) Escherichia coli CFT073 1040028 NP_756480.1 CDS gyrB NC_004431.1 4379441 4381858 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(4379441..4381858) Escherichia coli CFT073 1040039 NP_756481.1 CDS recF NC_004431.1 4381884 4382957 R Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F complement(4381884..4382957) Escherichia coli CFT073 1040040 NP_756482.1 CDS dnaN NC_004431.1 4382957 4384057 R binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta complement(4382957..4384057) Escherichia coli CFT073 1040053 NP_756483.1 CDS c4626 NC_004431.1 4385760 4385960 R hypothetical protein complement(4385760..4385960) Escherichia coli CFT073 1040056 NP_756484.1 CDS rpmH NC_004431.1 4386073 4386213 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4386073..4386213 Escherichia coli CFT073 1040142 NP_756485.1 CDS rnpA NC_004431.1 4386230 4386589 D protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4386230..4386589 Escherichia coli CFT073 1040070 NP_756486.1 CDS yidC NC_004431.1 4386813 4388459 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 4386813..4388459 Escherichia coli CFT073 1040071 NP_756487.1 CDS trmE NC_004431.1 4388565 4389929 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4388565..4389929 Escherichia coli CFT073 1040063 NP_756488.1 CDS tnaL NC_004431.1 4390171 4390245 D Escherichia coli K-12 ortholog: b3707; tryptophanase leader peptide 4390171..4390245 Escherichia coli CFT073 1040125 NP_756489.1 CDS tnaA NC_004431.1 4390451 4391881 D tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 4390451..4391881 Escherichia coli CFT073 1040088 NP_756490.1 CDS tnaB NC_004431.1 4391973 4393220 D tryptophan transporter of low affinity; tryptophan permease TnaB 4391973..4393220 Escherichia coli CFT073 1040072 NP_756491.1 CDS yidY NC_004431.1 4393352 4394527 D Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 4393352..4394527 Escherichia coli CFT073 1040098 NP_756492.1 CDS yidZ NC_004431.1 4394493 4395461 D Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 4394493..4395461 Escherichia coli CFT073 1040217 NP_756493.1 CDS yieE NC_004431.1 4395606 4396367 D Escherichia coli K-12 ortholog: b3712; Escherichia coli O157:H7 ortholog: z5207; hypothetical protein 4395606..4396367 Escherichia coli CFT073 1040126 NP_756494.1 CDS yieF NC_004431.1 4396389 4396955 D Escherichia coli K-12 ortholog: b3713; Escherichia coli O157:H7 ortholog: z5208; hypothetical protein 4396389..4396955 Escherichia coli CFT073 1040117 NP_756495.1 CDS yieG NC_004431.1 4397009 4398346 R Escherichia coli K-12 ortholog: b3714; Escherichia coli O157:H7 ortholog: z5209; hypothetical protein complement(4397009..4398346) Escherichia coli CFT073 1040215 NP_756496.1 CDS yieH NC_004431.1 4398513 4399178 D YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 4398513..4399178 Escherichia coli CFT073 1040089 NP_756497.1 CDS yieI NC_004431.1 4399245 4399718 D might be involved in hypersensitivity to nitrofurzone; inner membrane protein 4399245..4399718 Escherichia coli CFT073 1040143 NP_756498.1 CDS yieK NC_004431.1 4399800 4400522 R Escherichia coli K-12 ortholog: b3718; 6-phosphogluconolactonase complement(4399800..4400522) Escherichia coli CFT073 1040231 NP_756499.1 CDS yieL NC_004431.1 4400537 4401739 R Escherichia coli K-12 ortholog: b3719; hypothetical protein complement(4400537..4401739) Escherichia coli CFT073 1040228 NP_756500.1 CDS c4642 NC_004431.1 4401733 4403349 R Escherichia coli K-12 ortholog: b3720; hypothetical protein complement(4401733..4403349) Escherichia coli CFT073 1040219 NP_756501.1 CDS bglB NC_004431.1 4403435 4404829 R Escherichia coli K-12 ortholog: b3721; Escherichia coli O157:H7 ortholog: z4024; 6-phospho-beta-glucosidase complement(4403435..4404829) Escherichia coli CFT073 1040186 NP_756502.1 CDS bglF NC_004431.1 4404848 4406797 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system beta-glucoside-specific transporter subunits IIABC complement(4404848..4406797) Escherichia coli CFT073 1040227 NP_756503.1 CDS c4645 NC_004431.1 4405947 4406087 D hypothetical protein 4405947..4406087 Escherichia coli CFT073 1040190 NP_756504.1 CDS bglG NC_004431.1 4406856 4407716 R positive regulator of the beta-glucoside operon; transcriptional antiterminator; transcriptional antiterminator BglG complement(4406856..4407716) Escherichia coli CFT073 1040214 NP_756505.1 CDS c4647 NC_004431.1 4407758 4407880 D hypothetical protein 4407758..4407880 Escherichia coli CFT073 1040147 NP_756506.2 CDS phoU NC_004431.1 4407978 4408703 R regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU complement(4407978..4408703) Escherichia coli CFT073 1040241 NP_756507.1 CDS pstB NC_004431.1 4408718 4409491 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(4408718..4409491) Escherichia coli CFT073 1040237 NP_756508.1 CDS c4650 NC_004431.1 4408751 4409545 D hypothetical protein 4408751..4409545 Escherichia coli CFT073 1040222 NP_756509.1 CDS pstA NC_004431.1 4409582 4410472 R Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA complement(4409582..4410472) Escherichia coli CFT073 1040220 NP_756510.1 CDS pstC NC_004431.1 4410472 4411431 R part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC complement(4410472..4411431) Escherichia coli CFT073 1040236 NP_756511.1 CDS pstS NC_004431.1 4411518 4412558 R PBP; Escherichia coli K-12 ortholog: b3728; Escherichia coli O157:H7 ortholog: z5219; phosphate ABC transporter periplasmic substrate-binding protein PstS complement(4411518..4412558) Escherichia coli CFT073 1040226 NP_756512.1 CDS glmS NC_004431.1 4412872 4414701 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(4412872..4414701) Escherichia coli CFT073 1040221 NP_756513.1 CDS glmU NC_004431.1 4414862 4416232 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(4414862..4416232) Escherichia coli CFT073 1040271 NP_756514.1 CDS c4656 NC_004431.1 4416478 4417029 D hypothetical protein 4416478..4417029 Escherichia coli CFT073 1040238 NP_756515.1 CDS atpC NC_004431.1 4416586 4417005 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon complement(4416586..4417005) Escherichia coli CFT073 1040232 NP_756516.1 CDS atpD NC_004431.1 4417026 4418408 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta complement(4417026..4418408) Escherichia coli CFT073 1040230 NP_756517.1 CDS atpG NC_004431.1 4418435 4419298 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma complement(4418435..4419298) Escherichia coli CFT073 1040268 NP_756518.1 CDS atpA NC_004431.1 4419349 4420890 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha complement(4419349..4420890) Escherichia coli CFT073 1040243 NP_756519.1 CDS c4661 NC_004431.1 4419358 4421037 D hypothetical protein 4419358..4421037 Escherichia coli CFT073 1040235 NP_756520.1 CDS atpH NC_004431.1 4420903 4421436 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta complement(4420903..4421436) Escherichia coli CFT073 1040229 NP_756521.1 CDS c4663 NC_004431.1 4421077 4421814 D hypothetical protein 4421077..4421814 Escherichia coli CFT073 1040296 NP_756522.1 CDS atpF NC_004431.1 4421451 4421921 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B complement(4421451..4421921) Escherichia coli CFT073 1040262 NP_756523.1 CDS atpE NC_004431.1 4421983 4422222 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C complement(4421983..4422222) Escherichia coli CFT073 1040254 NP_756524.1 CDS atpB NC_004431.1 4422269 4423084 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A complement(4422269..4423084) Escherichia coli CFT073 1040240 NP_756525.2 CDS atpI NC_004431.1 4423093 4423473 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I complement(4423093..4423473) Escherichia coli CFT073 1040294 NP_756526.1 CDS gidB NC_004431.1 4424090 4424713 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(4424090..4424713) Escherichia coli CFT073 1040283 NP_756527.1 CDS gidA NC_004431.1 4424777 4426666 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA complement(4424777..4426666) Escherichia coli CFT073 1040249 NP_756528.1 CDS mioC NC_004431.1 4427045 4427488 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(4427045..4427488) Escherichia coli CFT073 1040246 NP_756529.1 CDS asnC NC_004431.1 4427578 4428036 R transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC complement(4427578..4428036) Escherichia coli CFT073 1040422 NP_756530.1 CDS asnA NC_004431.1 4428188 4429180 D catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4428188..4429180 Escherichia coli CFT073 1040297 NP_756531.1 CDS yieM NC_004431.1 4429185 4430636 R contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein complement(4429185..4430636) Escherichia coli CFT073 1040417 NP_756532.2 CDS yieN NC_004431.1 4430630 4432126 R interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA complement(4430630..4432126) Escherichia coli CFT073 1040287 NP_756533.1 CDS trkD NC_004431.1 4432349 4434217 D Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4432349..4434217 Escherichia coli CFT073 1040265 NP_756534.2 CDS rbsD NC_004431.1 4434384 4434803 D cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4434384..4434803 Escherichia coli CFT073 1040419 NP_756535.1 CDS rbsA NC_004431.1 4434811 4436316 D with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP binding protein 4434811..4436316 Escherichia coli CFT073 1040415 NP_756536.1 CDS rbsC NC_004431.1 4436321 4437286 D functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 4436321..4437286 Escherichia coli CFT073 1040281 NP_756537.1 CDS rbsB NC_004431.1 4437305 4438201 D periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4437305..4438201 Escherichia coli CFT073 1040291 NP_756538.2 CDS rbsK NC_004431.1 4438312 4439256 D catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4438312..4439256 Escherichia coli CFT073 1040427 NP_756539.1 CDS rbsR NC_004431.1 4439260 4440252 D DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR 4439260..4440252 Escherichia coli CFT073 1040457 NP_756540.1 CDS yieO NC_004431.1 4440218 4441645 R Escherichia coli K-12 ortholog: b3754; Escherichia coli O157:H7 ortholog: z5255; transport protein YieO complement(4440218..4441645) Escherichia coli CFT073 1040411 NP_756541.1 CDS yieP NC_004431.1 4441668 4442360 R Escherichia coli K-12 ortholog: b3755; Escherichia coli O157:H7 ortholog: z5258; transcriptional regulator YieP complement(4441668..4442360) Escherichia coli CFT073 1040464 NP_756542.1 CDS yifA NC_004431.1 4448165 4449004 R Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR complement(4448165..4449004) Escherichia coli CFT073 1036239 NP_756543.1 CDS yifE NC_004431.1 4449123 4449461 D Escherichia coli K-12 ortholog: b3764; Escherichia coli O157:H7 ortholog: z5276; hypothetical protein 4449123..4449461 Escherichia coli CFT073 1040507 NP_756544.1 CDS yifB NC_004431.1 4449486 4450571 R ORF III; Escherichia coli K-12 ortholog: b3765; Escherichia coli O157:H7 ortholog: z5277; bifunctional; hypothetical protein complement(4449486..4450571) Escherichia coli CFT073 1036114 NP_756545.1 CDS c4688 NC_004431.1 4450708 4451037 R Residues 1 to 95 of 109 are 100.00 pct identical to residues 1 to 95 of 516 from GenPept.129 : >gb|AAG58961.1|AE005608_2 (AE005608) 2-component regulator [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(4450708..4451037) Escherichia coli CFT073 1040473 NP_756546.1 CDS c4689 NC_004431.1 4451028 4451213 R hypothetical protein complement(4451028..4451213) Escherichia coli CFT073 1036343 NP_756547.1 CDS ilvL NC_004431.1 4451360 4451458 D Attenuator peptide; Escherichia coli K-12 ortholog: b3766; ilvG operon leader peptide 4451360..4451458 Escherichia coli CFT073 1040510 NP_756548.1 CDS ilvG NC_004431.1 4451598 4453244 D catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 4451598..4453244 Escherichia coli CFT073 1040479 NP_756549.1 CDS ilvM NC_004431.1 4453241 4453504 D Escherichia coli K-12 ortholog: b3769; Escherichia coli O157:H7 ortholog: z5280; acetolactate synthase 2 regulatory subunit 4453241..4453504 Escherichia coli CFT073 1036240 NP_756550.1 CDS ilvE NC_004431.1 4453524 4454453 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4453524..4454453 Escherichia coli CFT073 1036477 NP_756551.1 CDS ilvD NC_004431.1 4454518 4456368 D catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 4454518..4456368 Escherichia coli CFT073 1036478 NP_756552.1 CDS ilvA NC_004431.1 4456368 4457915 D threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 4456368..4457915 Escherichia coli CFT073 1036471 NP_756553.3 CDS ilvY NC_004431.1 4457912 4458886 R participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY complement(4457912..4458886) Escherichia coli CFT073 1035692 NP_756555.1 CDS ppiC NC_004431.1 4460473 4460754 R Escherichia coli K-12 ortholog: b3775; Escherichia coli O157:H7 ortholog: z5286; peptidyl-prolyl cis-trans isomerase C complement(4460473..4460754) Escherichia coli CFT073 1036466 NP_756556.1 CDS rep NC_004431.1 4460841 4462862 D single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 4460841..4462862 Escherichia coli CFT073 1036347 NP_756557.1 CDS gppA NC_004431.1 4462909 4464402 R catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase complement(4462909..4464402) Escherichia coli CFT073 1036485 NP_756558.1 CDS rhlB NC_004431.1 4464529 4465794 R enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB complement(4464529..4465794) Escherichia coli CFT073 1036487 NP_756559.1 CDS trxA NC_004431.1 4465820 4466254 D TRX1; Escherichia coli K-12 ortholog: b3781; Escherichia coli O157:H7 ortholog: z5291; thioredoxin 4465820..4466254 Escherichia coli CFT073 1036612 NP_756560.1 CDS rhoL NC_004431.1 4466395 4466496 D Escherichia coli K-12 ortholog: b3782; rho operon leader peptide 4466395..4466496 Escherichia coli CFT073 1036482 NP_756561.1 CDS rho NC_004431.1 4466509 4467840 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 4466509..4467840 Escherichia coli CFT073 1036474 NP_756562.1 CDS c4703 NC_004431.1 4467850 4467975 D Residues 1 to 41 of 41 are 97.56 pct identical to residues 1 to 41 of 72 from GenPept.129 : >gb|AAG58978.1|AE005610_2 (AE005610) Z5294 gene product [Escherichia coli O157:H7 EDL933]; hypothetical protein 4467850..4467975 Escherichia coli CFT073 1036475 NP_756563.1 CDS rfe NC_004431.1 4468080 4469183 D Escherichia coli K-12 ortholog: b3784; Escherichia coli O157:H7 ortholog: z5295; undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase 4468080..4469183 Escherichia coli CFT073 1036489 NP_756564.1 CDS wzzE NC_004431.1 4469192 4470241 D Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 4469192..4470241 Escherichia coli CFT073 1036488 NP_756565.1 CDS wecB NC_004431.1 4470255 4471427 D Escherichia coli K-12 ortholog: b3786; Escherichia coli O157:H7 ortholog: z5297; UDP-N-acetylglucosamine 2-epimerase 4470255..4471427 Escherichia coli CFT073 1036575 NP_756566.1 CDS wecC NC_004431.1 4471424 4472686 D catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 4471424..4472686 Escherichia coli CFT073 1035284 NP_756567.1 CDS rffG NC_004431.1 4472686 4473753 D Escherichia coli K-12 ortholog: b3788; Escherichia coli O157:H7 ortholog: z5299; dTDP-glucose 4,6-dehydratase 4472686..4473753 Escherichia coli CFT073 1040140 NP_756568.1 CDS rffH NC_004431.1 4473772 4474653 D Escherichia coli K-12 ortholog: b3789; Escherichia coli O157:H7 ortholog: z5300; glucose-1-phosphate thymidylyltransferase 4473772..4474653 Escherichia coli CFT073 1036425 NP_756569.1 CDS wecD NC_004431.1 4474631 4475305 D Escherichia coli K-12 ortholog: b3790; Escherichia coli O157:H7 ortholog: z5301; TDP-fucosamine acetyltransferase 4474631..4475305 Escherichia coli CFT073 1036364 NP_756570.1 CDS wecE NC_004431.1 4475310 4476440 D catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 4475310..4476440 Escherichia coli CFT073 1036493 NP_756571.1 CDS c4712 NC_004431.1 4475457 4476491 R hypothetical protein complement(4475457..4476491) Escherichia coli CFT073 1036479 NP_756572.1 CDS wzxE NC_004431.1 4476442 4477692 D Escherichia coli K-12 ortholog: b3792; Escherichia coli O157:H7 ortholog: z5303; WzxE protein 4476442..4477692 Escherichia coli CFT073 1036246 NP_756573.1 CDS c4714 NC_004431.1 4477689 4478768 D catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 4477689..4478768 Escherichia coli CFT073 1036507 NP_756574.1 CDS wecF NC_004431.1 4478765 4480117 D enterobacterial common antigen polymerase; common antigen polymerase 4478765..4480117 Escherichia coli CFT073 1035934 NP_756575.1 CDS wecG NC_004431.1 4480120 4480860 D Escherichia coli K-12 ortholog: b3794; Escherichia coli O157:H7 ortholog: z5306; UDP-N-acetyl-D-mannosaminuronic acid transferase 4480120..4480860 Escherichia coli CFT073 1035933 NP_756576.1 CDS yifK NC_004431.1 4481051 4482436 D uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; transport protein YifK 4481051..4482436 Escherichia coli CFT073 1036639 NP_756577.1 CDS aslB NC_004431.1 4483122 4484357 D Escherichia coli K-12 ortholog: b3800; Escherichia coli O157:H7 ortholog: z5313; arylsulfatase regulatory protein 4483122..4484357 Escherichia coli CFT073 1038202 NP_756578.1 CDS aslA NC_004431.1 4484515 4486170 R Escherichia coli K-12 ortholog: b3801; Escherichia coli O157:H7 ortholog: z5314; arylsulfatase complement(4484515..4486170) Escherichia coli CFT073 1038101 NP_756579.1 CDS c4720 NC_004431.1 4486067 4486222 D hypothetical protein 4486067..4486222 Escherichia coli CFT073 1036381 NP_756580.1 CDS hemY NC_004431.1 4486850 4488046 R Escherichia coli K-12 ortholog: b3802; Escherichia coli O157:H7 ortholog: z5316; protoheme IX biogenesis protein complement(4486850..4488046) Escherichia coli CFT073 1036500 NP_756581.1 CDS hemX NC_004431.1 4488049 4489266 R Escherichia coli K-12 ortholog: b3803; Escherichia coli O157:H7 ortholog: z5317; uroporphyrinogen III C-methyltransferase complement(4488049..4489266) Escherichia coli CFT073 1036497 NP_756582.1 CDS hemD NC_004431.1 4489288 4490028 R catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase complement(4489288..4490028) Escherichia coli CFT073 1035988 NP_756583.1 CDS hemC NC_004431.1 4490025 4490987 R transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase complement(4490025..4490987) Escherichia coli CFT073 1036562 NP_756584.1 CDS cyaA NC_004431.1 4491353 4493899 D catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 4491353..4493899 Escherichia coli CFT073 1035601 NP_756585.1 CDS cyaY NC_004431.1 4493939 4494259 R defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein complement(4493939..4494259) Escherichia coli CFT073 1035651 NP_756586.1 CDS c4727 NC_004431.1 4494307 4495626 R Residues 254 to 430 of 439 are 44.06 pct identical to residues 493 to 667 of 669 from GenPept.129 : >emb|CAD09375.1| (AL627279) possible exported protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein complement(4494307..4495626) Escherichia coli CFT073 1037438 NP_756587.1 CDS c4728 NC_004431.1 4495623 4497122 R Residues 11 to 499 of 499 are 62.62 pct identical to residues 1 to 495 of 669 from GenPept.129 : >emb|CAD09375.1| (AL627279) possible exported protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein complement(4495623..4497122) Escherichia coli CFT073 1038919 NP_756588.1 CDS c4729 NC_004431.1 4497281 4497484 D Escherichia coli O157:H7 ortholog: z5325; hypothetical protein 4497281..4497484 Escherichia coli CFT073 1035937 NP_756589.2 CDS dapF NC_004431.1 4497521 4498345 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 4497521..4498345 Escherichia coli CFT073 1035956 NP_756590.1 CDS yigA NC_004431.1 4498342 4499049 D Escherichia coli K-12 ortholog: b3810; Escherichia coli O157:H7 ortholog: z5327; hypothetical protein 4498342..4499049 Escherichia coli CFT073 1037537 NP_756591.1 CDS xerC NC_004431.1 4499046 4499942 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 4499046..4499942 Escherichia coli CFT073 1035725 NP_756592.1 CDS yigB NC_004431.1 4499942 4500658 D YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 4499942..4500658 Escherichia coli CFT073 1038182 NP_756593.2 CDS uvrD NC_004431.1 4500742 4502904 D unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 4500742..4502904 Escherichia coli CFT073 1035765 NP_756594.1 CDS c4735 NC_004431.1 4502959 4503861 R Escherichia coli O157:H7 ortholog: z5331; hypothetical protein complement(4502959..4503861) Escherichia coli CFT073 1038058 NP_756595.1 CDS c4736 NC_004431.1 4503944 4504708 R Escherichia coli O157:H7 ortholog: z5332; hypothetical protein complement(4503944..4504708) Escherichia coli CFT073 1035299 NP_756596.2 CDS corA NC_004431.1 4505078 4506028 D responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 4505078..4506028 Escherichia coli CFT073 1038460 NP_756597.1 CDS c4738 NC_004431.1 4506064 4506561 R Escherichia coli O157:H7 ortholog: z5334; hypothetical protein complement(4506064..4506561) Escherichia coli CFT073 1037641 NP_756598.1 CDS c4739 NC_004431.1 4506558 4507406 R Escherichia coli O157:H7 ortholog: z5335; hypothetical protein complement(4506558..4507406) Escherichia coli CFT073 1035936 NP_756599.1 CDS rarD NC_004431.1 4507717 4508607 R Escherichia coli K-12 ortholog: b3819; Escherichia coli O157:H7 ortholog: z5340; protein rarD complement(4507717..4508607) Escherichia coli CFT073 1035405 NP_756600.2 CDS yigI NC_004431.1 4508659 4509126 R Escherichia coli K-12 ortholog: b3820; Escherichia coli O157:H7 ortholog: z5341; hypothetical protein complement(4508659..4509126) Escherichia coli CFT073 1038510 NP_756601.1 CDS pldA NC_004431.1 4509290 4510159 D catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 4509290..4510159 Escherichia coli CFT073 1036509 NP_756602.1 CDS c4743 NC_004431.1 4510163 4510324 D hypothetical protein 4510163..4510324 Escherichia coli CFT073 1038737 NP_756603.1 CDS recQ NC_004431.1 4510278 4512113 D functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 4510278..4512113 Escherichia coli CFT073 1038269 NP_756604.1 CDS c4745 NC_004431.1 4512177 4512797 D Residues 1 to 206 of 206 are 99.02 pct identical to residues 1 to 206 of 206 from SwissProt.40 : >sp|P27846|RHTC_ECOLI Threonine efflux protein; threonine efflux system 4512177..4512797 Escherichia coli CFT073 1035003 NP_756605.1 CDS rhtB NC_004431.1 4512858 4513478 R Escherichia coli K-12 ortholog: b3824; Escherichia coli O157:H7 ortholog: z5345; homoserine/homoserine lactone efflux protein complement(4512858..4513478) Escherichia coli CFT073 1040456 NP_756606.1 CDS pldB NC_004431.1 4513589 4514611 D lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 4513589..4514611 Escherichia coli CFT073 1035613 NP_756607.1 CDS c4748 NC_004431.1 4514556 4515419 D purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; sugar phosphatase 4514556..4515419 Escherichia coli CFT073 1037281 NP_756608.1 CDS yigM NC_004431.1 4515420 4516394 D Escherichia coli K-12 ortholog: b3827; Escherichia coli O157:H7 ortholog: z5348; membrane protein yigM 4515420..4516394 Escherichia coli CFT073 1038265 NP_756609.1 CDS metR NC_004431.1 4516282 4517235 R Escherichia coli K-12 ortholog: b3828; Escherichia coli O157:H7 ortholog: z5349; transcriptional activator protein metR complement(4516282..4517235) Escherichia coli CFT073 1035353 NP_756610.1 CDS metE NC_004431.1 4517353 4519614 D catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 4517353..4519614 Escherichia coli CFT073 1034999 NP_756611.1 CDS c4752 NC_004431.1 4519621 4519746 R hypothetical protein complement(4519621..4519746) Escherichia coli CFT073 1037193 NP_756612.1 CDS c4753 NC_004431.1 4519783 4520043 R Residues 11 to 77 of 86 are 34.32 pct identical to residues 32 to 98 of 106 from GenPept.129 : >emb|CAD16922.1| (AL646075) CONSERVED HYPOTHETICAL PROTEIN [Ralstonia solanacearum]; hypothetical protein complement(4519783..4520043) Escherichia coli CFT073 1036655 NP_756613.1 CDS c4754 NC_004431.1 4520103 4520360 R Residues 6 to 73 of 85 are 33.82 pct identical to residues 31 to 98 of 106 from GenPept.129 : >emb|CAD16922.1| (AL646075) CONSERVED HYPOTHETICAL PROTEIN [Ralstonia solanacearum]; hypothetical protein complement(4520103..4520360) Escherichia coli CFT073 1035111 NP_756614.1 CDS c4755 NC_004431.1 4520357 4521046 R Residues 31 to 227 of 229 are 44.17 pct identical to residues 188 to 384 of 386 from GenPept.129 : >emb|CAD16923.1| (AL646075) PROBABLE TRANSMEMBRANE PROTEIN [Ralstonia solanacearum]; hypothetical protein complement(4520357..4521046) Escherichia coli CFT073 1035125 NP_756615.1 CDS c4756 NC_004431.1 4521725 4521856 D hypothetical protein 4521725..4521856 Escherichia coli CFT073 1038915 NP_756616.1 CDS c4757 NC_004431.1 4521963 4522532 D Residues 5 to 189 of 189 are 38.37 pct identical to residues 1 to 184 of 184 from GenPept.129 : >emb|CAD22377.1| (AX343668) unnamed protein product [Brevibacillus brevis]; hypothetical protein 4521963..4522532 Escherichia coli CFT073 1034996 NP_756617.1 CDS c4758 NC_004431.1 4522574 4524082 D EIIBC-Glc; Escherichia coli K-12 ortholog: b1101; Escherichia coli O157:H7 ortholog: z1740; PTS system, glucose-specific IIBC component 4522574..4524082 Escherichia coli CFT073 1038189 NP_756618.1 CDS c4759 NC_004431.1 4524133 4526130 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 4524133..4526130 Escherichia coli CFT073 1034973 NP_756619.1 CDS c4760 NC_004431.1 4526160 4527005 R Residues 10 to 262 of 281 are 28.34 pct identical to residues 15 to 268 of 287 from GenPept.129 : >dbj|BAB06394.1| (AP001516) transcriptional regulator (RpiR family) [Bacillus halodurans]; hypothetical protein complement(4526160..4527005) Escherichia coli CFT073 1038724 NP_756620.1 CDS c4761 NC_004431.1 4527206 4528111 R Residues 4 to 297 of 301 are 34.35 pct identical to residues 3 to 296 of 310 from MG1655 : b1659; hypothetical protein complement(4527206..4528111) Escherichia coli CFT073 1035776 NP_756621.1 CDS c4762 NC_004431.1 4528189 4529412 R Residues 14 to 395 of 407 are 28.42 pct identical to residues 27 to 419 of 445 from GenPept.129 : >dbj|BAB05601.1| (AP001513) cytosine permease [Bacillus halodurans]; permease complement(4528189..4529412) Escherichia coli CFT073 1035232 NP_756622.1 CDS c4763 NC_004431.1 4529438 4529827 R Residues 6 to 122 of 129 are 38.33 pct identical to residues 474 to 593 of 619 from GenPept.129 : >dbj|BAB53245.1| (AP003010) glutamyl-tRNA(Gln) amidotransferase subunit A [Mesorhizobium loti]; hypothetical protein complement(4529438..4529827) Escherichia coli CFT073 1037889 NP_756623.1 CDS c4764 NC_004431.1 4529844 4530800 R catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase complement(4529844..4530800) Escherichia coli CFT073 1034977 NP_756624.1 CDS c4765 NC_004431.1 4530793 4532268 R Escherichia coli K-12 ortholog: b0321; Escherichia coli O157:H7 ortholog: z0410; hypothetical protein complement(4530793..4532268) Escherichia coli CFT073 1036511 NP_756625.1 CDS c4766 NC_004431.1 4530799 4530939 D hypothetical protein 4530799..4530939 Escherichia coli CFT073 1037198 NP_756626.1 CDS c4767 NC_004431.1 4532214 4533773 R Escherichia coli K-12 ortholog: b0320; Escherichia coli O157:H7 ortholog: z0409; hypothetical protein complement(4532214..4533773) Escherichia coli CFT073 1035977 NP_756627.1 CDS c4768 NC_004431.1 4533868 4534728 R Residues 24 to 278 of 286 are 25.37 pct identical to residues 18 to 274 of 287 from GenPept.129 : >gb|AAG54663.1|AE005210_7 (AE005210) orf, hypothetical protein [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(4533868..4534728) Escherichia coli CFT073 1035657 NP_756628.1 CDS c4769 NC_004431.1 4534734 4535333 R Residues 1 to 197 of 199 are 56.78 pct identical to residues 34 to 232 of 233 from GenPept.129 : >dbj|BAB53241.1| (AP003010) hypothetical protein [Mesorhizobium loti]; hypothetical protein complement(4534734..4535333) Escherichia coli CFT073 1035239 NP_756629.1 CDS c4770 NC_004431.1 4535368 4535517 R hypothetical protein complement(4535368..4535517) Escherichia coli CFT073 1038242 NP_756630.1 CDS c4771 NC_004431.1 4535659 4536534 R Escherichia coli O157:H7 ortholog: z5352; carboxymethylenebutenolidase complement(4535659..4536534) Escherichia coli CFT073 1035267 NP_756632.2 CDS udp NC_004431.1 4536730 4537494 D catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 4536730..4537494 Escherichia coli CFT073 1038346 NP_756631.1 CDS c4772 NC_004431.1 4536775 4537509 R hypothetical protein complement(4536775..4537509) Escherichia coli CFT073 1037710 NP_756633.1 CDS c4774 NC_004431.1 4537529 4539019 R Residues 19 to 496 of 496 are 46.99 pct identical to residues 16 to 493 of 504 from GenPept.129 : >dbj|BAB05728.1| (AP001514) BH2009; unknown conserved protein in others [Bacillus halodurans]; hypothetical protein complement(4537529..4539019) Escherichia coli CFT073 1036472 NP_756634.1 CDS c4775 NC_004431.1 4539032 4539541 R Residues 52 to 165 of 169 are 31.66 pct identical to residues 28 to 144 of 147 from GenPept.129 : >gb|AAL94188.1| (AE010513) unknown [Fusobacterium nucleatum subsp. nucleatum ATCC 25586]; hypothetical protein complement(4539032..4539541) Escherichia coli CFT073 1035667 NP_756635.1 CDS c4776 NC_004431.1 4539555 4540529 R Residues 31 to 322 of 324 are 33.44 pct identical to residues 15 to 307 of 308 from GenPept.129 : >gb|AAL94187.1| (AE010513) RecA protein [Fusobacterium nucleatum subsp. nucleatum ATCC 25586]; hypothetical protein complement(4539555..4540529) Escherichia coli CFT073 1038104 NP_756636.1 CDS c4777 NC_004431.1 4540554 4541183 R catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase complement(4540554..4541183) Escherichia coli CFT073 1036819 NP_756637.1 CDS c4778 NC_004431.1 4541173 4542177 R Residues 7 to 319 of 334 are 34.38 pct identical to residues 5 to 289 of 292 from MG1655 : b3693; hypothetical protein complement(4541173..4542177) Escherichia coli CFT073 1035670 NP_756638.1 CDS c4779 NC_004431.1 4542201 4543055 R Residues 40 to 273 of 284 are 32.36 pct identical to residues 2 to 242 of 254 from GenPept.129 : >emb|CAC40602.1| (AL591857) IclR-family transcriptional regulatory protein [Streptomyces coelicolor]; transcriptional regulator complement(4542201..4543055) Escherichia coli CFT073 1035310 NP_756639.1 CDS c4780 NC_004431.1 4543132 4543290 D hypothetical protein 4543132..4543290 Escherichia coli CFT073 1038725 NP_756640.1 CDS yigN NC_004431.1 4543185 4544612 D YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 4543185..4544612 Escherichia coli CFT073 1035262 NP_756641.1 CDS ubiE NC_004431.1 4544707 4545462 D Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4544707..4545462 Escherichia coli CFT073 1038327 NP_756642.1 CDS yigP NC_004431.1 4545431 4546081 D Escherichia coli K-12 ortholog: b3834; Escherichia coli O157:H7 ortholog: z5356; hypothetical protein 4545431..4546081 Escherichia coli CFT073 1035938 NP_756643.1 CDS ubiB NC_004431.1 4546078 4547718 D an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; ubiquinone biosynthesis protein UbiB 4546078..4547718 Escherichia coli CFT073 1038139 NP_756644.1 CDS tatA NC_004431.1 4547755 4548066 D TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 4547755..4548066 Escherichia coli CFT073 1036512 NP_756645.1 CDS c4786 NC_004431.1 4548070 4548585 D mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 4548070..4548585 Escherichia coli CFT073 1037187 NP_756646.1 CDS yigU NC_004431.1 4548588 4549364 D with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 4548588..4549364 Escherichia coli CFT073 1035673 NP_756647.1 CDS yigW NC_004431.1 4549394 4550188 D magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 4549394..4550188 Escherichia coli CFT073 1035668 NP_756648.1 CDS rfaH NC_004431.1 4550185 4550673 R Escherichia coli K-12 ortholog: b3842; Escherichia coli O157:H7 ortholog: z5362; transcriptional activator RfaH complement(4550185..4550673) Escherichia coli CFT073 1035846 NP_756649.1 CDS yigC NC_004431.1 4550840 4552333 D catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 4550840..4552333 Escherichia coli CFT073 1035828 NP_756650.2 CDS fre NC_004431.1 4552379 4553080 D NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 4552379..4553080 Escherichia coli CFT073 1035669 NP_756651.1 CDS fadA NC_004431.1 4553272 4554435 R FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase complement(4553272..4554435) Escherichia coli CFT073 1038239 NP_756652.2 CDS fadB NC_004431.1 4554445 4556634 R includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha complement(4554445..4556634) Escherichia coli CFT073 1035892 NP_756653.1 CDS pepQ NC_004431.1 4556824 4558155 D catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 4556824..4558155 Escherichia coli CFT073 1035710 NP_756654.1 CDS yigZ NC_004431.1 4558152 4558769 D Escherichia coli K-12 ortholog: b3848; Escherichia coli O157:H7 ortholog: z5370; hypothetical protein 4558152..4558769 Escherichia coli CFT073 1036031 NP_756655.1 CDS trkH NC_004431.1 4558808 4560259 D Escherichia coli K-12 ortholog: b3849; Escherichia coli O157:H7 ortholog: z5371; potassium transporter 4558808..4560259 Escherichia coli CFT073 1035672 NP_756656.1 CDS hemG NC_004431.1 4560271 4560816 D catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 4560271..4560816 Escherichia coli CFT073 1038229 NP_756657.1 CDS mobB NC_004431.1 4566397 4566924 R in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein B complement(4566397..4566924) Escherichia coli CFT073 1035666 NP_756658.1 CDS mobA NC_004431.1 4566906 4567490 R in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA complement(4566906..4567490) Escherichia coli CFT073 1035939 NP_756659.1 CDS yihD NC_004431.1 4567530 4567829 D Escherichia coli K-12 ortholog: b3858; Escherichia coli O157:H7 ortholog: z5390; hypothetical protein 4567530..4567829 Escherichia coli CFT073 1038221 NP_756660.1 CDS yihE NC_004431.1 4567906 4568892 D catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 4567906..4568892 Escherichia coli CFT073 1038199 NP_756661.1 CDS dsbA NC_004431.1 4568909 4569535 D Escherichia coli K-12 ortholog: b3860; Escherichia coli O157:H7 ortholog: z5392; periplasmic protein disulfide isomerase I 4568909..4569535 Escherichia coli CFT073 1036525 NP_756662.1 CDS c4805 NC_004431.1 4569560 4569700 D hypothetical protein 4569560..4569700 Escherichia coli CFT073 1036045 NP_756663.1 CDS yihF NC_004431.1 4569648 4571120 D Escherichia coli K-12 ortholog: b3861; Escherichia coli O157:H7 ortholog: z5393; hypothetical protein 4569648..4571120 Escherichia coli CFT073 1035727 NP_756664.2 CDS yihG NC_004431.1 4571161 4572093 R Escherichia coli K-12 ortholog: b3862; Escherichia coli O157:H7 ortholog: z5394; acyltransferase complement(4571161..4572093) Escherichia coli CFT073 1038235 NP_756665.1 CDS c4808 NC_004431.1 4572213 4572455 R hypothetical protein complement(4572213..4572455) Escherichia coli CFT073 1038192 NP_756666.1 CDS c4811 NC_004431.1 4575461 4575610 R hypothetical protein complement(4575461..4575610) Escherichia coli CFT073 1038204 NP_756667.2 CDS engB NC_004431.1 4575624 4576256 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(4575624..4576256) Escherichia coli CFT073 1038231 NP_756668.1 CDS c4813 NC_004431.1 4576275 4576415 R hypothetical protein complement(4576275..4576415) Escherichia coli CFT073 1036527 NP_756669.1 CDS c4814 NC_004431.1 4576723 4576869 R hypothetical protein complement(4576723..4576869) Escherichia coli CFT073 1038201 NP_756670.1 CDS yihI NC_004431.1 4576838 4577347 D Escherichia coli K-12 ortholog: b3866; Escherichia coli O157:H7 ortholog: z5402; hypothetical protein 4576838..4577347 Escherichia coli CFT073 1036054 NP_756671.2 CDS hemN NC_004431.1 4577536 4578909 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4577536..4578909 Escherichia coli CFT073 1038210 NP_756672.2 CDS glnG NC_004431.1 4579364 4580773 R response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) complement(4579364..4580773) Escherichia coli CFT073 1035991 NP_756673.1 CDS glnL NC_004431.1 4580785 4581834 R sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) complement(4580785..4581834) Escherichia coli CFT073 1035716 NP_756674.1 CDS glnA NC_004431.1 4582008 4583417 R forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase complement(4582008..4583417) Escherichia coli CFT073 1036016 NP_756675.1 CDS yihK NC_004431.1 4583790 4585613 D Tyrosine phosphorylated protein A; Escherichia coli K-12 ortholog: b3871; Escherichia coli O157:H7 ortholog: z5407; GTP-binding protein 4583790..4585613 Escherichia coli CFT073 1036449 NP_756676.1 CDS yihL NC_004431.1 4585831 4586541 D Escherichia coli K-12 ortholog: b3872; Escherichia coli O157:H7 ortholog: z5408; transcriptional regulator YihL 4585831..4586541 Escherichia coli CFT073 1040466 NP_756677.1 CDS yihM NC_004431.1 4586549 4587529 D Escherichia coli K-12 ortholog: b3873; Escherichia coli O157:H7 ortholog: z5409; hypothetical protein 4586549..4587529 Escherichia coli CFT073 1036007 NP_756678.1 CDS yihN NC_004431.1 4587631 4588896 D Escherichia coli K-12 ortholog: b3874; Escherichia coli O157:H7 ortholog: z5410; hypothetical protein 4587631..4588896 Escherichia coli CFT073 1036017 NP_756679.1 CDS yihW NC_004431.1 4588956 4589744 R Escherichia coli K-12 ortholog: b3884; Escherichia coli O157:H7 ortholog: z5422; transcriptional regulator YihW complement(4588956..4589744) Escherichia coli CFT073 1038216 NP_756680.3 CDS yihV NC_004431.1 4589784 4590731 R Escherichia coli K-12 ortholog: b3883; Escherichia coli O157:H7 ortholog: z5421; sugar kinase yihV complement(4589784..4590731) Escherichia coli CFT073 1038180 NP_756681.1 CDS yihU NC_004431.1 4590652 4591731 D Escherichia coli K-12 ortholog: b3882; Escherichia coli O157:H7 ortholog: z5420; oxidoreductase yihU 4590652..4591731 Escherichia coli CFT073 1038185 NP_756682.1 CDS yihT NC_004431.1 4591756 4592643 D Escherichia coli K-12 ortholog: b3881; Escherichia coli O157:H7 ortholog: z5418; hypothetical protein 4591756..4592643 Escherichia coli CFT073 1038200 NP_756683.1 CDS c4828 NC_004431.1 4592676 4593686 D Zinc binding; Residues 29 to 330 of 336 are 33.64 pct identical to residues 45 to 365 of 368 from GenPept.129 : >gb|AAK71492.1| (AY037946) sorbitol dehydrogenase [Prunus cerasus]; dehydrogenase 4592676..4593686 Escherichia coli CFT073 1035975 NP_756684.1 CDS c4829 NC_004431.1 4593756 4595189 D Residues 30 to 455 of 477 are 22.60 pct identical to residues 62 to 476 of 486 from GenPept.129 : >emb|CAC11594.1| (AL445064) sugar transport protein related protein [Thermoplasma acidophilum]; hypothetical protein 4593756..4595189 Escherichia coli CFT073 1038181 NP_756685.1 CDS c4830 NC_004431.1 4595288 4596637 D Escherichia coli K-12 ortholog: b1981; Escherichia coli O157:H7 ortholog: z3138; shikimate transporter 4595288..4596637 Escherichia coli CFT073 1036448 NP_756686.1 CDS c4831 NC_004431.1 4596570 4597514 D Residues 46 to 310 of 314 are 43.39 pct identical to residues 4 to 259 of 262 from GenPept.129 : >emb|CAB42038.1| (AL049754) hypothetical protein [Streptomyces coelicolor A3(2)]; hypothetical protein 4596570..4597514 Escherichia coli CFT073 1038211 NP_756687.3 CDS yihX NC_004431.1 4597634 4598254 D Escherichia coli K-12 ortholog: b3885; Escherichia coli O157:H7 ortholog: z5424; phosphatase 4597634..4598254 Escherichia coli CFT073 1038207 NP_756688.1 CDS rbn NC_004431.1 4598248 4599120 D RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 4598248..4599120 Escherichia coli CFT073 1036574 NP_756689.1 CDS yihZ NC_004431.1 4599117 4599554 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 4599117..4599554 Escherichia coli CFT073 1036075 NP_756690.1 CDS yiiD NC_004431.1 4599551 4600540 D Escherichia coli K-12 ortholog: b3888; Escherichia coli O157:H7 ortholog: z5427; hypothetical protein 4599551..4600540 Escherichia coli CFT073 1037527 NP_756691.1 CDS c4836 NC_004431.1 4600604 4601524 R Residues 5 to 303 of 306 are 74.91 pct identical to residues 1 to 299 of 309 from GenPept.129 : >emb|CAD09594.1| (AL627279) lipase [Salmonella enterica subsp. enterica serovar Typhi]; lipase complement(4600604..4601524) Escherichia coli CFT073 1038198 NP_756692.1 CDS c4837 NC_004431.1 4601742 4602053 D Residues 2 to 103 of 103 are 41.17 pct identical to residues 4 to 105 of 110 from GenPept.129 : >gb|AAF96372.1| (AE004379) hypothetical protein [Vibrio cholerae]; hypothetical protein 4601742..4602053 Escherichia coli CFT073 1034926 NP_756693.1 CDS c4838 NC_004431.1 4602054 4602344 D Residues 13 to 94 of 96 are 87.80 pct identical to residues 1 to 82 of 84 from GenPept.129 : >gb|AAL22872.1| (AE008888) bacterial regulatory protein, merR family [Salmonella typhimurium LT2]; hypothetical protein 4602054..4602344 Escherichia coli CFT073 1040465 NP_756694.1 CDS c4839 NC_004431.1 4602703 4602981 D hypothetical protein 4602703..4602981 Escherichia coli CFT073 1040462 NP_756695.1 CDS yiiE NC_004431.1 4603350 4603595 D Escherichia coli K-12 ortholog: b3889; Escherichia coli O157:H7 ortholog: z5431; hypothetical protein 4603350..4603595 Escherichia coli CFT073 1040452 NP_756696.1 CDS fdhE NC_004431.1 4603811 4604740 R required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE complement(4603811..4604740) Escherichia coli CFT073 1040447 NP_756697.1 CDS fdoI NC_004431.1 4604737 4605372 R cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma complement(4604737..4605372) Escherichia coli CFT073 1040444 NP_756698.1 CDS fdoH NC_004431.1 4605369 4606271 R Iron-sulfur subunit; Escherichia coli K-12 ortholog: b3893; Escherichia coli O157:H7 ortholog: z5435; formate dehydrogenase-O beta subunit complement(4605369..4606271) Escherichia coli CFT073 1040442 NP_756699.1 CDS fdoG NC_004431.1 4606284 4609334 R Escherichia coli K-12 ortholog: b3894; Escherichia coli O157:H7 ortholog: z5436; formate dehydrogenase-O, major subunit complement(4606284..4609334) Escherichia coli CFT073 1040441 NP_756700.1 CDS c4846 NC_004431.1 4608966 4609592 D hypothetical protein 4608966..4609592 Escherichia coli CFT073 1040439 NP_756701.1 CDS fdhD NC_004431.1 4609528 4610361 D involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 4609528..4610361 Escherichia coli CFT073 1040436 NP_756702.1 CDS c4848 NC_004431.1 4610449 4611003 D Residues 1 to 163 of 184 are 74.51 pct identical to residues 139 to 346 of 351 from MG1655 : b3896; hypothetical protein 4610449..4611003 Escherichia coli CFT073 1040300 NP_756703.1 CDS c4849 NC_004431.1 4611357 4612730 D Escherichia coli O157:H7 ortholog: z5444; glycoporin 4611357..4612730 Escherichia coli CFT073 1040253 NP_756704.1 CDS yiiL NC_004431.1 4612771 4613085 R Escherichia coli K-12 ortholog: b3901; Escherichia coli O157:H7 ortholog: z5445; hypothetical protein complement(4612771..4613085) Escherichia coli CFT073 1040252 NP_756705.1 CDS rhaD NC_004431.1 4613095 4614012 R Escherichia coli K-12 ortholog: b3902; Escherichia coli O157:H7 ortholog: z5446; rhamnulose-1-phosphate aldolase complement(4613095..4614012) Escherichia coli CFT073 1040225 NP_756706.1 CDS rhaA NC_004431.1 4614380 4615645 R catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase complement(4614380..4615645) Escherichia coli CFT073 1040224 NP_756707.1 CDS rhaB NC_004431.1 4615636 4617105 R catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase complement(4615636..4617105) Escherichia coli CFT073 1040218 NP_756708.1 CDS c4854 NC_004431.1 4617184 4617333 D hypothetical protein 4617184..4617333 Escherichia coli CFT073 1040216 NP_756709.1 CDS rhaS NC_004431.1 4617393 4618229 D activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 4617393..4618229 Escherichia coli CFT073 1040213 NP_756710.1 CDS rhaR NC_004431.1 4618192 4619151 D activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 4618192..4619151 Escherichia coli CFT073 1040212 NP_756711.1 CDS rhaT NC_004431.1 4619148 4620182 R transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter complement(4619148..4620182) Escherichia coli CFT073 1040211 NP_756712.1 CDS c4858 NC_004431.1 4620147 4620314 D hypothetical protein 4620147..4620314 Escherichia coli CFT073 1040210 NP_756713.1 CDS sodA NC_004431.1 4620462 4621088 D SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 4620462..4621088 Escherichia coli CFT073 1040208 NP_756714.1 CDS c4860 NC_004431.1 4621117 4621245 R hypothetical protein complement(4621117..4621245) Escherichia coli CFT073 1040207 NP_756715.2 CDS kdgT NC_004431.1 4621348 4622331 D transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 4621348..4622331 Escherichia coli CFT073 1040205 NP_756716.2 CDS yiiM NC_004431.1 4622480 4623154 D Escherichia coli K-12 ortholog: b3910; Escherichia coli O157:H7 ortholog: z5455; hypothetical protein 4622480..4623154 Escherichia coli CFT073 1040203 NP_756717.1 CDS cpxA NC_004431.1 4623260 4624633 R part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein complement(4623260..4624633) Escherichia coli CFT073 1040202 NP_756718.1 CDS cpxR NC_004431.1 4624630 4625328 R response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR complement(4624630..4625328) Escherichia coli CFT073 1040201 NP_756719.2 CDS cpxP NC_004431.1 4625478 4625978 D repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; periplasmic repressor CpxP 4625478..4625978 Escherichia coli CFT073 1040200 NP_756720.2 CDS fieF NC_004431.1 4626127 4627029 D member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 4626127..4627029 Escherichia coli CFT073 1040197 NP_756721.1 CDS pfkA NC_004431.1 4627114 4628172 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 4627114..4628172 Escherichia coli CFT073 1040196 NP_756722.1 CDS c4868 NC_004431.1 4628431 4628568 D hypothetical protein 4628431..4628568 Escherichia coli CFT073 1040194 NP_756723.1 CDS sbp NC_004431.1 4628492 4629481 D Sulfate starvation-induced protein 2; Escherichia coli K-12 ortholog: b3917; Escherichia coli O157:H7 ortholog: z5462; sulfate transporter subunit 4628492..4629481 Escherichia coli CFT073 1040192 NP_756724.1 CDS cdh NC_004431.1 4629396 4630343 D Escherichia coli K-12 ortholog: b3918; Escherichia coli O157:H7 ortholog: z5463; CDP-diacylglycerol pyrophosphatase 4629396..4630343 Escherichia coli CFT073 1040191 NP_756725.1 CDS tpiA NC_004431.1 4630398 4631165 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(4630398..4631165) Escherichia coli CFT073 1040189 NP_756726.1 CDS yiiQ NC_004431.1 4631273 4631872 R Escherichia coli K-12 ortholog: b3920; Escherichia coli O157:H7 ortholog: z5465; hypothetical protein complement(4631273..4631872) Escherichia coli CFT073 1040188 NP_756727.1 CDS yiiR NC_004431.1 4631973 4632413 D Escherichia coli K-12 ortholog: b3921; Escherichia coli O157:H7 ortholog: z5466; hypothetical protein 4631973..4632413 Escherichia coli CFT073 1040185 NP_756728.1 CDS yiiS NC_004431.1 4632625 4632924 D Escherichia coli K-12 ortholog: b3922; Escherichia coli O157:H7 ortholog: z5467; hypothetical protein 4632625..4632924 Escherichia coli CFT073 1040183 NP_756729.1 CDS yiiT NC_004431.1 4632951 4633379 D with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 4632951..4633379 Escherichia coli CFT073 1040181 NP_756730.1 CDS fpr NC_004431.1 4633384 4634130 R Escherichia coli K-12 ortholog: b3924; Escherichia coli O157:H7 ortholog: z5469; ferredoxin-NADP reductase complement(4633384..4634130) Escherichia coli CFT073 1040178 NP_756731.1 CDS glpX NC_004431.1 4634227 4635237 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(4634227..4635237) Escherichia coli CFT073 1040175 NP_756732.1 CDS glpK NC_004431.1 4635408 4637021 R Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase complement(4635408..4637021) Escherichia coli CFT073 1040170 NP_756733.1 CDS glpF NC_004431.1 4636939 4637784 R Aquaglyceroporin; Escherichia coli K-12 ortholog: b3927; Escherichia coli O157:H7 ortholog: z5472; glycerol uptake facilitator protein complement(4636939..4637784) Escherichia coli CFT073 1040169 NP_756734.1 CDS yiiU NC_004431.1 4638191 4638454 D Escherichia coli K-12 ortholog: b3928; Escherichia coli O157:H7 ortholog: z5473; hypothetical protein 4638191..4638454 Escherichia coli CFT073 1040166 NP_756735.1 CDS menG NC_004431.1 4638539 4639024 R regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA complement(4638539..4639024) Escherichia coli CFT073 1040164 NP_756736.1 CDS c4882 NC_004431.1 4638596 4639102 D hypothetical protein 4638596..4639102 Escherichia coli CFT073 1040160 NP_756737.1 CDS menA NC_004431.1 4639117 4640055 R catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase complement(4639117..4640055) Escherichia coli CFT073 1040156 NP_756738.1 CDS hslU NC_004431.1 4640110 4641441 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU complement(4640110..4641441) Escherichia coli CFT073 1040155 NP_756739.1 CDS hslV NC_004431.1 4641451 4641981 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit complement(4641451..4641981) Escherichia coli CFT073 1040153 NP_756740.1 CDS ftsN NC_004431.1 4642074 4643033 R Escherichia coli K-12 ortholog: b3933; Escherichia coli O157:H7 ortholog: z5480; essential cell division protein FtsN complement(4642074..4643033) Escherichia coli CFT073 1040152 NP_756741.1 CDS cytR NC_004431.1 4643125 4644150 R negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR complement(4643125..4644150) Escherichia coli CFT073 1040151 NP_756742.1 CDS priA NC_004431.1 4644306 4646576 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(4644306..4646576) Escherichia coli CFT073 1040145 NP_756743.1 CDS c4889 NC_004431.1 4646689 4646829 R hypothetical protein complement(4646689..4646829) Escherichia coli CFT073 1040141 NP_756744.1 CDS yiiX NC_004431.1 4646980 4647588 R member of the NlpC/P60 superfamily of peptidases; peptidoglycan peptidase complement(4646980..4647588) Escherichia coli CFT073 1040139 NP_756745.1 CDS metJ NC_004431.1 4647648 4648103 R when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ complement(4647648..4648103) Escherichia coli CFT073 1040138 NP_756746.1 CDS metB NC_004431.1 4648128 4649402 D catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 4648128..4649402 Escherichia coli CFT073 1040136 NP_756747.1 CDS metL NC_004431.1 4649405 4651837 D multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 4649405..4651837 Escherichia coli CFT073 1040134 NP_756748.1 CDS c4894 NC_004431.1 4652055 4652915 R Escherichia coli K-12 ortholog: b0411; Escherichia coli O157:H7 ortholog: z0512; nucleoside-specific channel-forming protein tsx complement(4652055..4652915) Escherichia coli CFT073 1040130 NP_756749.1 CDS c4895 NC_004431.1 4652992 4654617 R Residues 10 to 537 of 541 are 64.65 pct identical to residues 5 to 513 of 518 from GenPept.129 : >gb|AAL22944.1| (AE008891) 5'-nucleotidase/2',3'-cyclic phosphodiesterase or related esterase [Salmonella typhimurium LT2]; hypothetical protein complement(4652992..4654617) Escherichia coli CFT073 1040128 NP_756750.1 CDS c4896 NC_004431.1 4654652 4656205 R Residues 3 to 517 of 517 are 58.95 pct identical to residues 7 to 523 of 523 from GenPept.129 : >gb|AAL18997.1| (AE008694) 5'-nucleotidase [Salmonella typhimurium LT2]; hypothetical protein complement(4654652..4656205) Escherichia coli CFT073 1040123 NP_756751.1 CDS c4897 NC_004431.1 4656435 4657559 R Residues 1 to 367 of 374 are 61.68 pct identical to residues 1 to 368 of 374 from GenPept.129 : >gb|AAL22943.1| (AE008891) cytoplasmic protein [Salmonella typhimurium LT2]; hypothetical protein complement(4656435..4657559) Escherichia coli CFT073 1040119 NP_756752.1 CDS c4898 NC_004431.1 4657686 4659245 D Residues 3 to 519 of 519 are 91.87 pct identical to residues 1 to 517 of 518 from GenPept.129 : >gb|AAL22944.1| (AE008891) 5'-nucleotidase/2',3'-cyclic phosphodiesterase or related esterase [Salmonella typhimurium LT2]; hypothetical protein 4657686..4659245 Escherichia coli CFT073 1040116 NP_756753.1 CDS metF NC_004431.1 4659627 4660517 D MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 4659627..4660517 Escherichia coli CFT073 1040113 NP_756754.1 CDS katG NC_004431.1 4660807 4663026 D Escherichia coli K-12 ortholog: b3942; Escherichia coli O157:H7 ortholog: z5497; peroxidase/catalase HPI 4660807..4663026 Escherichia coli CFT073 1040112 NP_756755.1 CDS yijE NC_004431.1 4663054 4664025 D Escherichia coli K-12 ortholog: b3943; Escherichia coli O157:H7 ortholog: z5498; transport protein YijE 4663054..4664025 Escherichia coli CFT073 1040110 NP_756756.1 CDS yijF NC_004431.1 4664052 4664669 R Escherichia coli K-12 ortholog: b3944; Escherichia coli O157:H7 ortholog: z5499; hypothetical protein complement(4664052..4664669) Escherichia coli CFT073 1040109 NP_756757.1 CDS c4903 NC_004431.1 4664569 4664763 R hypothetical protein complement(4664569..4664763) Escherichia coli CFT073 1040108 NP_756758.2 CDS gldA NC_004431.1 4664945 4666048 R forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase complement(4664945..4666048) Escherichia coli CFT073 1040105 NP_756759.1 CDS talC NC_004431.1 4666059 4666721 R similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase complement(4666059..4666721) Escherichia coli CFT073 1040104 NP_756760.1 CDS ptsA NC_004431.1 4666733 4669234 R Escherichia coli K-12 ortholog: b3947; Escherichia coli O157:H7 ortholog: z5502; phosphoenolpyruvate-protein phosphotransferase ptsA complement(4666733..4669234) Escherichia coli CFT073 1040102 NP_756761.1 CDS frwC NC_004431.1 4669543 4670622 D FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; fructose-like permease EIIC subunit 2 4669543..4670622 Escherichia coli CFT073 1040100 NP_756762.1 CDS frwB NC_004431.1 4670637 4670957 D FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; PTS system fructose-like transporter subunit EIIB 4670637..4670957 Escherichia coli CFT073 1040099 NP_756763.1 CDS c4909 NC_004431.1 4670670 4670996 R hypothetical protein complement(4670670..4670996) Escherichia coli CFT073 1040097 NP_756764.1 CDS pflD NC_004431.1 4671008 4673305 D involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; formate acetyltransferase 2 4671008..4673305 Escherichia coli CFT073 1040094 NP_756765.1 CDS pflC NC_004431.1 4673271 4674149 D Escherichia coli K-12 ortholog: b3952; Escherichia coli O157:H7 ortholog: z5508; pyruvate formate lyase II activase 4673271..4674149 Escherichia coli CFT073 1040091 NP_756766.1 CDS frwD NC_004431.1 4674151 4674492 D FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; fructose-like phosphotransferase EIIB subunit 3 4674151..4674492 Escherichia coli CFT073 1040090 NP_756767.1 CDS yijO NC_004431.1 4674479 4675330 R Escherichia coli K-12 ortholog: b3954; Escherichia coli O157:H7 ortholog: z5512; transcriptional regulator YijO complement(4674479..4675330) Escherichia coli CFT073 1040083 NP_756768.2 CDS yijP NC_004431.1 4675556 4677289 R Escherichia coli K-12 ortholog: b3955; Escherichia coli O157:H7 ortholog: z5513; hypothetical protein complement(4675556..4677289) Escherichia coli CFT073 1040081 NP_756769.1 CDS ppc NC_004431.1 4677472 4680123 R catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase complement(4677472..4680123) Escherichia coli CFT073 1040079 NP_756770.1 CDS argE NC_004431.1 4680425 4681615 R catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase complement(4680425..4681615) Escherichia coli CFT073 1040075 NP_756771.1 CDS argC NC_004431.1 4681730 4682734 D catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 4681730..4682734 Escherichia coli CFT073 1040073 NP_756772.2 CDS argB NC_004431.1 4682745 4683518 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 4682745..4683518 Escherichia coli CFT073 1040069 NP_756773.1 CDS argH NC_004431.1 4683579 4684952 D catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 4683579..4684952 Escherichia coli CFT073 1040068 NP_756774.1 CDS c4920 NC_004431.1 4685450 4686664 D Escherichia coli K-12 ortholog: b1581; starvation sensing protein rspA 4685450..4686664 Escherichia coli CFT073 1040066 NP_756775.1 CDS yjiZ NC_004431.1 4686731 4688014 D Escherichia coli K-12 ortholog: b4356; Escherichia coli O157:H7 ortholog: z5956; transport protein YjjL 4686731..4688014 Escherichia coli CFT073 1040060 NP_756776.2 CDS oxyR NC_004431.1 4688266 4689183 D Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 4688266..4689183 Escherichia coli CFT073 1040058 NP_756777.1 CDS udhA NC_004431.1 4689166 4690566 R catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase complement(4689166..4690566) Escherichia coli CFT073 1040055 NP_756778.1 CDS c4924 NC_004431.1 4690896 4692062 D Escherichia coli O157:H7 ortholog: z5522; hippuricase 4690896..4692062 Escherichia coli CFT073 1040050 NP_756779.1 CDS c4925 NC_004431.1 4692105 4693421 D Escherichia coli O157:H7 ortholog: z5523; citrate permease 4692105..4693421 Escherichia coli CFT073 1040046 NP_756780.1 CDS yijC NC_004431.1 4693471 4694175 D negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 4693471..4694175 Escherichia coli CFT073 1040045 NP_756781.1 CDS yijD NC_004431.1 4694175 4694534 D Escherichia coli K-12 ortholog: b3964; Escherichia coli O157:H7 ortholog: z5525; hypothetical protein 4694175..4694534 Escherichia coli CFT073 1040034 NP_756782.1 CDS trmA NC_004431.1 4694574 4695674 R catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase complement(4694574..4695674) Escherichia coli CFT073 1040031 NP_756783.2 CDS btuB NC_004431.1 4696043 4697887 D involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 4696043..4697887 Escherichia coli CFT073 1040029 NP_756784.1 CDS murI NC_004431.1 4697832 4698689 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 4697832..4698689 Escherichia coli CFT073 1040024 NP_756785.1 CDS murB NC_004431.1 4704305 4705333 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 4704305..4705333 Escherichia coli CFT073 1039893 NP_756786.1 CDS birA NC_004431.1 4705330 4706295 D catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 4705330..4706295 Escherichia coli CFT073 1039892 NP_756787.1 CDS coaA NC_004431.1 4706324 4707295 R catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase complement(4706324..4707295) Escherichia coli CFT073 1039891 NP_756788.1 CDS c4934 NC_004431.1 4707331 4707492 R Residues 1 to 53 of 53 are 96.22 pct identical to residues 1 to 53 of 53 from SwissProt.40 : >sp|P15045|YZRS_ECOLI VERY HYPOTHETICAL 6.2 KD PROTEIN IN RTS 5'REGION; hypothetical protein complement(4707331..4707492) Escherichia coli CFT073 1039890 NP_756789.1 CDS tuf NC_004431.1 4708192 4709376 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 4708192..4709376 Escherichia coli CFT073 1039881 NP_756790.1 CDS secE NC_004431.1 4709606 4709989 D forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 4709606..4709989 Escherichia coli CFT073 1039880 NP_756791.1 CDS nusG NC_004431.1 4709991 4710536 D Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 4709991..4710536 Escherichia coli CFT073 1039879 NP_756792.1 CDS c4938 NC_004431.1 4710641 4711642 R hypothetical protein complement(4710641..4711642) Escherichia coli CFT073 1039877 NP_756793.1 CDS rplK NC_004431.1 4710695 4711123 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 4710695..4711123 Escherichia coli CFT073 1039875 NP_756794.1 CDS rplA NC_004431.1 4711127 4711831 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 4711127..4711831 Escherichia coli CFT073 1039874 NP_756795.1 CDS rplJ NC_004431.1 4712123 4712620 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 4712123..4712620 Escherichia coli CFT073 1039873 NP_756796.1 CDS c4942 NC_004431.1 4712672 4713178 R hypothetical protein complement(4712672..4713178) Escherichia coli CFT073 1039872 NP_756797.1 CDS rplL NC_004431.1 4712687 4713052 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 4712687..4713052 Escherichia coli CFT073 1039871 NP_756798.1 CDS rpoB NC_004431.1 4713339 4717400 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 4713339..4717400 Escherichia coli CFT073 1039870 NP_756799.1 CDS rpoC NC_004431.1 4717477 4721700 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 4717477..4721700 Escherichia coli CFT073 1039869 NP_756800.1 CDS thiH NC_004431.1 4721942 4723075 R in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH complement(4721942..4723075) Escherichia coli CFT073 1039868 NP_756801.2 CDS thiG NC_004431.1 4723072 4723842 R functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase complement(4723072..4723842) Escherichia coli CFT073 1039866 NP_756802.1 CDS thiS NC_004431.1 4723844 4724044 R with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS complement(4723844..4724044) Escherichia coli CFT073 1039865 NP_756803.3 CDS thiF NC_004431.1 4724028 4724798 R catalyzes the adenylation of ThiS which is involved in the formation of 5-methyl-4-(beta-hydroxyethyl)thiazole phosphate; adenylyltransferase complement(4724028..4724798) Escherichia coli CFT073 1039863 NP_756804.1 CDS thiE NC_004431.1 4724776 4725414 R catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase complement(4724776..4725414) Escherichia coli CFT073 1039862 NP_756805.1 CDS thiC NC_004431.1 4725411 4727318 R required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC complement(4725411..4727318) Escherichia coli CFT073 1039860 NP_756806.1 CDS yjaE NC_004431.1 4727539 4728015 R binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor complement(4727539..4728015) Escherichia coli CFT073 1039858 NP_756807.1 CDS nudC NC_004431.1 4728110 4728883 D can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 4728110..4728883 Escherichia coli CFT073 1039857 NP_756808.1 CDS hemE NC_004431.1 4728923 4729987 D catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 4728923..4729987 Escherichia coli CFT073 1039856 NP_756809.1 CDS nfi NC_004431.1 4729997 4730668 D Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 4729997..4730668 Escherichia coli CFT073 1039855 NP_756810.1 CDS yjaG NC_004431.1 4730711 4731301 D Escherichia coli K-12 ortholog: b3999; Escherichia coli O157:H7 ortholog: z5575; hypothetical protein 4730711..4731301 Escherichia coli CFT073 1039854 NP_756811.1 CDS hupA NC_004431.1 4731488 4731760 D histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 4731488..4731760 Escherichia coli CFT073 1039853 NP_756812.1 CDS yjaH NC_004431.1 4731767 4732468 D Escherichia coli K-12 ortholog: b4001; Escherichia coli O157:H7 ortholog: z5577; hypothetical protein 4731767..4732468 Escherichia coli CFT073 1039851 NP_756813.3 CDS zraP NC_004431.1 4732470 4733030 R Escherichia coli K-12 ortholog: b4002; Escherichia coli O157:H7 ortholog: z5578; zinc resistance protein complement(4732470..4733030) Escherichia coli CFT073 1039849 NP_756814.1 CDS c4960 NC_004431.1 4732892 4733020 R hypothetical protein complement(4732892..4733020) Escherichia coli CFT073 1039848 NP_756815.1 CDS hydH NC_004431.1 4733127 4734503 D Escherichia coli K-12 ortholog: b4003; Escherichia coli O157:H7 ortholog: z5579; sensor protein ZraS 4733127..4734503 Escherichia coli CFT073 1039846 NP_756816.1 CDS hydG NC_004431.1 4734500 4735825 D DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR 4734500..4735825 Escherichia coli CFT073 1039844 NP_756817.1 CDS purD NC_004431.1 4735822 4737111 R catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase complement(4735822..4737111) Escherichia coli CFT073 1039843 NP_756818.1 CDS purH NC_004431.1 4737123 4738712 R involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase complement(4737123..4738712) Escherichia coli CFT073 1039842 NP_756819.1 CDS c4965 NC_004431.1 4738830 4738952 D hypothetical protein 4738830..4738952 Escherichia coli CFT073 1039841 NP_756820.1 CDS yjaA NC_004431.1 4744384 4744803 D Escherichia coli K-12 ortholog: b4011; hypothetical protein 4744384..4744803 Escherichia coli CFT073 1039833 NP_756821.1 CDS yjaB NC_004431.1 4744867 4745310 R Escherichia coli K-12 ortholog: b4012; Escherichia coli O157:H7 ortholog: z5598; hypothetical protein complement(4744867..4745310) Escherichia coli CFT073 1039831 NP_756822.1 CDS metA NC_004431.1 4745467 4746396 D catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 4745467..4746396 Escherichia coli CFT073 1039773 NP_756823.1 CDS aceB NC_004431.1 4746647 4748266 D Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 4746647..4748266 Escherichia coli CFT073 1039772 NP_756824.1 CDS aceA NC_004431.1 4748281 4749600 D Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates; isocitrate lyase 4748281..4749600 Escherichia coli CFT073 1039771 NP_756825.1 CDS c4973 NC_004431.1 4749615 4749761 D Residues 3 to 46 of 48 are 61.70 pct identical to residues 21 to 67 of 103 from GenPept.129 : >gb|AAB18079.1| (U73857) hypothetical protein [Escherichia coli]; hypothetical protein 4749615..4749761 Escherichia coli CFT073 1039770 NP_756826.1 CDS aceK NC_004431.1 4749816 4751540 D catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase protein 4749816..4751540 Escherichia coli CFT073 1039769 NP_756827.2 CDS iclR NC_004431.1 4751557 4752381 R regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; transcriptional repressor IclR complement(4751557..4752381) Escherichia coli CFT073 1039766 NP_756828.1 CDS metH NC_004431.1 4752581 4756264 D one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 4752581..4756264 Escherichia coli CFT073 1039765 NP_756829.1 CDS c4977 NC_004431.1 4756318 4756644 D hypothetical protein 4756318..4756644 Escherichia coli CFT073 1039763 NP_756830.1 CDS c4978 NC_004431.1 4756687 4757136 D Residues 6 to 145 of 149 are 32.85 pct identical to residues 4 to 137 of 138 from GenPept.129 : >emb|CAC92271.1| (AJ414155) membrane protein [Yersinia pestis]; hypothetical protein 4756687..4757136 Escherichia coli CFT073 1039762 NP_756831.1 CDS yjbB NC_004431.1 4757307 4758938 D Escherichia coli K-12 ortholog: b4020; Escherichia coli O157:H7 ortholog: z5611; hypothetical protein 4757307..4758938 Escherichia coli CFT073 1039761 NP_756832.1 CDS pepE NC_004431.1 4759028 4759717 R alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E complement(4759028..4759717) Escherichia coli CFT073 1039759 NP_756833.1 CDS c4981 NC_004431.1 4760099 4761328 R Escherichia coli K-12 ortholog: b2931; Escherichia coli O157:H7 ortholog: z5613; oxidoreductase complement(4760099..4761328) Escherichia coli CFT073 1039757 NP_756834.1 CDS c4982 NC_004431.1 4761380 4762234 R EIID-Man; Escherichia coli K-12 ortholog: b1819; Escherichia coli O157:H7 ortholog: z5614; PTS system, mannose-specific IID component complement(4761380..4762234) Escherichia coli CFT073 1039753 NP_756835.1 CDS c4983 NC_004431.1 4762215 4763012 R EIIC-Man; Escherichia coli K-12 ortholog: b1818; Escherichia coli O157:H7 ortholog: z5615; PTS system, mannose-specific IIC component complement(4762215..4763012) Escherichia coli CFT073 1039752 NP_756836.1 CDS c4984 NC_004431.1 4763078 4763572 R Escherichia coli O157:H7 ortholog: z5616; sorbose PTS component complement(4763078..4763572) Escherichia coli CFT073 1039741 NP_756837.1 CDS c4985 NC_004431.1 4763572 4763979 R Escherichia coli O157:H7 ortholog: z5617; sorbose PTS component complement(4763572..4763979) Escherichia coli CFT073 1039738 NP_756838.1 CDS c4986 NC_004431.1 4763989 4764795 R Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; sorbitol-6-phosphate 2-dehydrogenase complement(4763989..4764795) Escherichia coli CFT073 1039729 NP_756839.1 CDS c4987 NC_004431.1 4764865 4765896 R Escherichia coli O157:H7 ortholog: z5619; transcriptional regulator of sorbose uptake and utilization genes complement(4764865..4765896) Escherichia coli CFT073 1039719 NP_756840.1 CDS yjbC NC_004431.1 4766160 4767032 D catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 4766160..4767032 Escherichia coli CFT073 1039712 NP_756841.1 CDS yjbD NC_004431.1 4767033 4767305 R Escherichia coli K-12 ortholog: b4023; Escherichia coli O157:H7 ortholog: z5621; hypothetical protein complement(4767033..4767305) Escherichia coli CFT073 1039707 NP_756842.1 CDS lysC NC_004431.1 4767558 4768907 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase complement(4767558..4768907) Escherichia coli CFT073 1039699 NP_756843.2 CDS pgi NC_004431.1 4769432 4771081 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 4769432..4771081 Escherichia coli CFT073 1039694 YP_004853836.1 CDS c4992 NC_004431.1 4771477 4771971 R hypothetical protein complement(4771477..4771971) Escherichia coli CFT073 1039692 YP_004853837.1 CDS c4993 NC_004431.1 4771560 4771889 R hypothetical protein complement(4771560..4771889) Escherichia coli CFT073 1039620 NP_756846.1 CDS yjbE NC_004431.1 4771579 4771821 D Escherichia coli K-12 ortholog: b4026; Escherichia coli O157:H7 ortholog: z5624; hypothetical protein 4771579..4771821 Escherichia coli CFT073 1039615 NP_756847.1 CDS yjbF NC_004431.1 4771978 4772646 D Escherichia coli K-12 ortholog: b4027; Escherichia coli O157:H7 ortholog: z5625; lipoprotein yjbF 4771978..4772646 Escherichia coli CFT073 1039614 NP_756848.1 CDS yjbG NC_004431.1 4772643 4773380 D Escherichia coli K-12 ortholog: b4028; Escherichia coli O157:H7 ortholog: z5626; hypothetical protein 4772643..4773380 Escherichia coli CFT073 1039612 NP_756849.1 CDS yjbH NC_004431.1 4773380 4775476 D Escherichia coli K-12 ortholog: b4029; Escherichia coli O157:H7 ortholog: z5627; lipoprotein yjbH 4773380..4775476 Escherichia coli CFT073 1039611 NP_756850.1 CDS c4998 NC_004431.1 4775480 4775641 D hypothetical protein 4775480..4775641 Escherichia coli CFT073 1039610 NP_756851.1 CDS c4999 NC_004431.1 4775523 4775801 R hypothetical protein complement(4775523..4775801) Escherichia coli CFT073 1039609 NP_756852.1 CDS c5000 NC_004431.1 4775798 4775920 R hypothetical protein complement(4775798..4775920) Escherichia coli CFT073 1039606 NP_756853.1 CDS yjbA NC_004431.1 4776016 4776426 D Escherichia coli K-12 ortholog: b4030; Escherichia coli O157:H7 ortholog: z5628; phosphate-starvation-inducible protein PsiE 4776016..4776426 Escherichia coli CFT073 1039600 NP_756854.1 CDS malG NC_004431.1 4776520 4777410 R with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease complement(4776520..4777410) Escherichia coli CFT073 1039585 NP_756855.1 CDS malF NC_004431.1 4777425 4778984 R with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein complement(4777425..4778984) Escherichia coli CFT073 1039565 NP_756856.1 CDS malE NC_004431.1 4779123 4780313 R functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein complement(4779123..4780313) Escherichia coli CFT073 1039564 NP_756857.1 CDS malK NC_004431.1 4780588 4781793 D with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 4780588..4781793 Escherichia coli CFT073 1039562 NP_756858.1 CDS lamB NC_004431.1 4781865 4783205 D porin involved in the transport of maltose and maltodextrins; maltoporin 4781865..4783205 Escherichia coli CFT073 1039561 NP_756859.1 CDS malM NC_004431.1 4783428 4784357 D Escherichia coli K-12 ortholog: b4037; Escherichia coli O157:H7 ortholog: z5635; maltose regulon periplasmic protein 4783428..4784357 Escherichia coli CFT073 1039555 NP_756860.1 CDS c5008 NC_004431.1 4784370 4784522 D hypothetical protein 4784370..4784522 Escherichia coli CFT073 1039552 NP_756861.1 CDS ubiC NC_004431.1 4784536 4785033 D catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 4784536..4785033 Escherichia coli CFT073 1039545 NP_756862.1 CDS ubiA NC_004431.1 4785046 4785918 D catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 4785046..4785918 Escherichia coli CFT073 1039481 NP_756863.2 CDS plsB NC_004431.1 4786073 4788496 R PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase complement(4786073..4788496) Escherichia coli CFT073 1039432 NP_756864.1 CDS c5012 NC_004431.1 4788342 4788704 R hypothetical protein complement(4788342..4788704) Escherichia coli CFT073 1039399 NP_756865.1 CDS dgkA NC_004431.1 4788667 4789035 D Escherichia coli K-12 ortholog: b4042; Escherichia coli O157:H7 ortholog: z5641; diacylglycerol kinase 4788667..4789035 Escherichia coli CFT073 1039398 NP_756866.1 CDS lexA NC_004431.1 4789145 4789753 D Represses a number of genes involved in the response to DNA damage; LexA repressor 4789145..4789753 Escherichia coli CFT073 1039346 NP_756867.2 CDS dinF NC_004431.1 4789826 4791151 D Escherichia coli K-12 ortholog: b4044; Escherichia coli O157:H7 ortholog: z5643; DNA-damage-inducible SOS response protein 4789826..4791151 Escherichia coli CFT073 1039344 NP_756868.1 CDS yjbJ NC_004431.1 4791261 4791476 D unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; stress-response protein 4791261..4791476 Escherichia coli CFT073 1039343 NP_756869.2 CDS yjbK NC_004431.1 4791518 4792033 R Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor complement(4791518..4792033) Escherichia coli CFT073 1039338 NP_756870.1 CDS yjbN NC_004431.1 4792189 4793184 D Escherichia coli K-12 ortholog: b4049; Escherichia coli O157:H7 ortholog: z5647; tRNA-dihydrouridine synthase A 4792189..4793184 Escherichia coli CFT073 1039337 NP_756871.2 CDS pspG NC_004431.1 4793318 4793560 D coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 4793318..4793560 Escherichia coli CFT073 1039331 NP_756872.1 CDS qor NC_004431.1 4793725 4794708 R Escherichia coli K-12 ortholog: b4051; Escherichia coli O157:H7 ortholog: z5649; quinone oxidoreductase, NADPH-dependent complement(4793725..4794708) Escherichia coli CFT073 1039326 NP_756873.1 CDS c5021 NC_004431.1 4794814 4796979 R Residues 70 to 648 of 721 are 36.66 pct identical to residues 6 to 596 of 664 from GenPept.129 : >gb|AAD35512.1|AE001721_11 (AE001721) oxidoreductase, [Thermotoga maritima]; oxidoreductase complement(4794814..4796979) Escherichia coli CFT073 1039324 NP_756874.1 CDS c5022 NC_004431.1 4796852 4798252 R Residues 18 to 448 of 466 are 40.90 pct identical to residues 24 to 452 of 453 from GenPept.129 : >emb|CAB72806.1| (AL139074) transmembrane transport protein [Campylobacter jejuni]; transmembrane transport protein complement(4796852..4798252) Escherichia coli CFT073 1039322 NP_756875.1 CDS c5023 NC_004431.1 4798343 4799122 R Residues 14 to 256 of 259 are 43.20 pct identical to residues 13 to 254 of 256 from GenPept.129 : >gb|AAK65427.1| (AE007264) dehydratase [Sinorhizobium meliloti]; crotonase complement(4798343..4799122) Escherichia coli CFT073 1039320 NP_756876.1 CDS c5024 NC_004431.1 4799115 4800686 R Residues 5 to 517 of 523 are 68.03 pct identical to residues 3 to 514 of 533 from GenPept.129 : >dbj|BAB50030.1| (AP003001) Acetyl-CoA:acetoacetyl-CoA transferase a subunit [Mesorhizobium loti]; propionate CoA-transferase complement(4799115..4800686) Escherichia coli CFT073 1039309 NP_756877.1 CDS c5025 NC_004431.1 4800915 4801976 D Residues 16 to 349 of 353 are 38.46 pct identical to residues 2 to 335 of 347 from GenPept.129 : >emb|CAC47885.1| (AL591793) TRANSCRIPTION REGULATOR PROTEIN [Sinorhizobium meliloti]; regulator 4800915..4801976 Escherichia coli CFT073 1039307 NP_756878.1 CDS dnaB NC_004431.1 4802013 4803464 D unwinds double stranded DNA; replicative DNA helicase 4802013..4803464 Escherichia coli CFT073 1039305 NP_756879.1 CDS c5027 NC_004431.1 4803499 4804239 R hypothetical protein complement(4803499..4804239) Escherichia coli CFT073 1039300 NP_756880.1 CDS alr NC_004431.1 4804186 4805265 D converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 4804186..4805265 Escherichia coli CFT073 1039290 NP_756881.1 CDS c5029 NC_004431.1 4805288 4805845 D Residues 1 to 181 of 185 are 36.81 pct identical to residues 1 to 182 of 191 from GenPept.129 : >gb|AAG05346.1|AE004622_8 (AE004622) probable transporter [Pseudomonas aeruginosa]; transporter 4805288..4805845 Escherichia coli CFT073 1039284 NP_756882.1 CDS c5030 NC_004431.1 4805818 4806846 D Residues 15 to 342 of 342 are 32.32 pct identical to residues 4 to 317 of 323 from GenPept.129 : >emb|CAB07007.1| (Z92669) nadR [Mycobacterium tuberculosis H37Rv]; NadR-like protein 4805818..4806846 Escherichia coli CFT073 1039283 NP_756883.2 CDS tyrB NC_004431.1 4806928 4808121 D catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 4806928..4808121 Escherichia coli CFT073 1039275 NP_756884.1 CDS sucA NC_004431.1 4808228 4811047 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 4808228..4811047 Escherichia coli CFT073 1039269 NP_756885.1 CDS c5033 NC_004431.1 4810920 4811120 R hypothetical protein complement(4810920..4811120) Escherichia coli CFT073 1039265 NP_756886.1 CDS c5034 NC_004431.1 4811179 4812234 D Escherichia coli K-12 ortholog: b0727; Escherichia coli O157:H7 ortholog: z0881; dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex 4811179..4812234 Escherichia coli CFT073 1039262 NP_756887.1 CDS c5035 NC_004431.1 4812246 4813664 D Residues 1 to 468 of 472 are 49.04 pct identical to residues 1 to 470 of 474 from SwissProt.40 : >sp|P52992|DLDH_ALCEU DIHYDROLIPOAMIDE DEHYDROGENASE (E3 COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX); 2-oxoglutarate dehydrogenase 4812246..4813664 Escherichia coli CFT073 1039261 NP_756888.1 CDS c5036 NC_004431.1 4813686 4814855 D Escherichia coli K-12 ortholog: b0728; Escherichia coli O157:H7 ortholog: z0882; succinyl-CoA synthetase subunit beta 4813686..4814855 Escherichia coli CFT073 1039258 NP_756889.1 CDS c5037 NC_004431.1 4814868 4815740 D Escherichia coli K-12 ortholog: b0729; Escherichia coli O157:H7 ortholog: z0883; succinyl-CoA synthetase subunit alpha 4814868..4815740 Escherichia coli CFT073 1039251 NP_756890.1 CDS c5038 NC_004431.1 4815946 4817451 D Residues 10 to 499 of 501 are 60.28 pct identical to residues 20 to 511 of 513 from SwissProt.40 : >sp|Q07252|MEMP_ALCEU MEMBRANE PROTEIN; membrane-bound protein 4815946..4817451 Escherichia coli CFT073 1039246 NP_756891.1 CDS c5039 NC_004431.1 4817427 4818536 D Residues 15 to 344 of 369 are 44.87 pct identical to residues 1 to 332 of 349 from SwissProt.40 : >sp|Q07251|LDH_ALCEU L-lactate dehydrogenase; lactate dehydrogenase 4817427..4818536 Escherichia coli CFT073 1039244 NP_756892.1 CDS c5040 NC_004431.1 4818525 4819883 R Residues 10 to 441 of 452 are 51.61 pct identical to residues 7 to 439 of 448 from SwissProt.40 : >sp|P10046|DCTD_RHILE C4-DICARBOXYLATE TRANSPORT TRANSCRIPTIONAL REGULATORY PROTEIN DCTD; c4-dicarboxylate transport transcriptional regulatory protein complement(4818525..4819883) Escherichia coli CFT073 1039243 NP_756893.1 CDS c5041 NC_004431.1 4819876 4821696 R Residues 20 to 591 of 606 are 31.81 pct identical to residues 28 to 612 of 633 from GenPept.129 : >gb|AAG04725.1|AE004563_2 (AE004563) probable two-component sensor [Pseudomonas aeruginosa]; transport sensor protein complement(4819876..4821696) Escherichia coli CFT073 1039242 NP_756894.1 CDS c5042 NC_004431.1 4821518 4821652 D hypothetical protein 4821518..4821652 Escherichia coli CFT073 1039240 NP_756895.1 CDS c5043 NC_004431.1 4821668 4821808 R hypothetical protein complement(4821668..4821808) Escherichia coli CFT073 1039227 NP_756896.1 CDS c5044 NC_004431.1 4821812 4821964 D hypothetical protein 4821812..4821964 Escherichia coli CFT073 1039221 NP_756897.1 CDS aphA NC_004431.1 4821973 4822686 D Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 4821973..4822686 Escherichia coli CFT073 1039218 NP_756898.1 CDS yjbQ NC_004431.1 4822797 4823213 D Escherichia coli K-12 ortholog: b4056; Escherichia coli O157:H7 ortholog: z5655; hypothetical protein 4822797..4823213 Escherichia coli CFT073 1039217 NP_756899.1 CDS yjbR NC_004431.1 4823217 4823573 D Escherichia coli K-12 ortholog: b4057; Escherichia coli O157:H7 ortholog: z5656; hypothetical protein 4823217..4823573 Escherichia coli CFT073 1039214 NP_756900.1 CDS uvrA NC_004431.1 4823608 4826430 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(4823608..4826430) Escherichia coli CFT073 1039212 NP_756901.1 CDS ssb NC_004431.1 4826685 4827221 D binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 4826685..4827221 Escherichia coli CFT073 1039210 NP_756902.1 CDS yjcB NC_004431.1 4827320 4827700 R Escherichia coli K-12 ortholog: b4060; Escherichia coli O157:H7 ortholog: z5659; hypothetical protein complement(4827320..4827700) Escherichia coli CFT073 1039209 NP_756903.1 CDS c5051 NC_004431.1 4827688 4827822 D hypothetical protein 4827688..4827822 Escherichia coli CFT073 1039207 NP_756904.1 CDS yjcC NC_004431.1 4828021 4829583 D Escherichia coli K-12 ortholog: b4061; Escherichia coli O157:H7 ortholog: z5660; hypothetical protein 4828021..4829583 Escherichia coli CFT073 1039201 NP_756905.1 CDS soxS NC_004431.1 4829619 4829942 R regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS complement(4829619..4829942) Escherichia coli CFT073 1039200 NP_756906.1 CDS soxR NC_004431.1 4830028 4830492 D Escherichia coli K-12 ortholog: b4063; Escherichia coli O157:H7 ortholog: z5662; redox-sensitive transcriptional activator SoxR 4830028..4830492 Escherichia coli CFT073 1039198 NP_756907.1 CDS c5055 NC_004431.1 4830900 4831139 D hypothetical protein 4830900..4831139 Escherichia coli CFT073 1039186 NP_756908.1 CDS c5056 NC_004431.1 4831040 4832389 D Escherichia coli K-12 ortholog: b4064; Escherichia coli O157:H7 ortholog: z5663; hypothetical protein 4831040..4832389 Escherichia coli CFT073 1039185 NP_756909.1 CDS c5057 NC_004431.1 4832540 4834189 D Escherichia coli K-12 ortholog: b4065; Escherichia coli O157:H7 ortholog: z5664; Na(+)/H(+) exchanger yjcE 4832540..4834189 Escherichia coli CFT073 1039181 NP_756910.1 CDS c5058 NC_004431.1 4834225 4835109 R Residues 1 to 291 of 294 are 89.04 pct identical to residues 1 to 292 of 295 from GenPept.129 : >emb|CAD09254.1| (AL627282) lysR family regulatory protein [Salmonella enterica subsp. enterica serovar Typhi]; transcriptional regulator complement(4834225..4835109) Escherichia coli CFT073 1039175 NP_756911.1 CDS c5059 NC_004431.1 4835121 4835249 D hypothetical protein 4835121..4835249 Escherichia coli CFT073 1039169 NP_756912.1 CDS c5060 NC_004431.1 4835219 4835623 D Residues 1 to 133 of 134 are 84.96 pct identical to residues 3 to 135 of 136 from GenPept.129 : >gb|AAL23095.1| (AE008900) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein 4835219..4835623 Escherichia coli CFT073 1039166 NP_756913.1 CDS c5061 NC_004431.1 4835616 4836305 D Residues 1 to 229 of 229 are 89.95 pct identical to residues 1 to 229 of 229 from GenPept.129 : >gb|AAL23096.1| (AE008900) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein 4835616..4836305 Escherichia coli CFT073 1039162 NP_756914.1 CDS actP NC_004431.1 4836344 4837993 R member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease complement(4836344..4837993) Escherichia coli CFT073 1039154 NP_756915.1 CDS yjcH NC_004431.1 4837990 4838307 R Escherichia coli K-12 ortholog: b4068; Escherichia coli O157:H7 ortholog: z5667; hypothetical protein complement(4837990..4838307) Escherichia coli CFT073 1039152 NP_756916.1 CDS acs NC_004431.1 4838698 4840656 R Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase complement(4838698..4840656) Escherichia coli CFT073 1039151 NP_756917.1 CDS c5065 NC_004431.1 4840930 4841127 D hypothetical protein 4840930..4841127 Escherichia coli CFT073 1038787 NP_756918.1 CDS nrfA NC_004431.1 4841048 4842484 D catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 4841048..4842484 Escherichia coli CFT073 1038754 NP_756919.1 CDS nrfB NC_004431.1 4842523 4843095 D part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia; cytochrome c nitrite reductase pentaheme subunit 4842523..4843095 Escherichia coli CFT073 1038752 NP_756920.1 CDS nrfC NC_004431.1 4843092 4843763 D Escherichia coli K-12 ortholog: b4072; Escherichia coli O157:H7 ortholog: z5671; NrfC protein 4843092..4843763 Escherichia coli CFT073 1038749 NP_756921.1 CDS nrfD NC_004431.1 4843760 4844716 D Escherichia coli K-12 ortholog: b4073; Escherichia coli O157:H7 ortholog: z5672; NrfD protein 4843760..4844716 Escherichia coli CFT073 1038748 NP_756922.1 CDS nrfE NC_004431.1 4844772 4846454 D with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 4844772..4846454 Escherichia coli CFT073 1038747 NP_756923.1 CDS nrfF NC_004431.1 4846447 4846830 D Escherichia coli K-12 ortholog: b4075; Escherichia coli O157:H7 ortholog: z5674; formate-dependent nitrite reductase complex subunit NrfF 4846447..4846830 Escherichia coli CFT073 1038746 NP_756924.1 CDS nrfG NC_004431.1 4846827 4847423 D Escherichia coli K-12 ortholog: b4076; Escherichia coli O157:H7 ortholog: z5675; formate-dependent nitrite reductase complex subunit NrfG 4846827..4847423 Escherichia coli CFT073 1038744 NP_756925.1 CDS c5073 NC_004431.1 4847558 4847689 R hypothetical protein complement(4847558..4847689) Escherichia coli CFT073 1038743 NP_756926.1 CDS gltP NC_004431.1 4847766 4849079 D carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 4847766..4849079 Escherichia coli CFT073 1038742 NP_756927.1 CDS c5075 NC_004431.1 4849989 4850147 D hypothetical protein 4849989..4850147 Escherichia coli CFT073 1038667 NP_756928.1 CDS yjcO NC_004431.1 4850133 4850876 R Escherichia coli K-12 ortholog: b4078; Escherichia coli O157:H7 ortholog: z5677; hypothetical protein complement(4850133..4850876) Escherichia coli CFT073 1038642 NP_756929.1 CDS yddO NC_004431.1 4850933 4851637 R Escherichia coli K-12 ortholog: b1483; Escherichia coli O157:H7 ortholog: z2227; ABC transporter ATP-binding protein complement(4850933..4851637) Escherichia coli CFT073 1038604 NP_756930.1 CDS c5078 NC_004431.1 4851624 4852520 R Residues 21 to 287 of 298 are 62.98 pct identical to residues 1 to 281 of 292 from GenPept.129 : >emb|CAC92681.1| (AJ414157) ABC transporter transporter, ATP-binding protein [Yersinia pestis]; oligopeptide ABC transporter complement(4851624..4852520) Escherichia coli CFT073 1038590 NP_756931.1 CDS yddQ NC_004431.1 4852453 4853286 R Escherichia coli K-12 ortholog: b1485; Escherichia coli O157:H7 ortholog: z2225; ABC transporter permease complement(4852453..4853286) Escherichia coli CFT073 1038569 NP_756932.1 CDS yddR NC_004431.1 4853286 4854428 R Escherichia coli K-12 ortholog: b1486; Escherichia coli O157:H7 ortholog: z2224; ABC transporter permease complement(4853286..4854428) Escherichia coli CFT073 1038560 NP_756933.1 CDS c5081 NC_004431.1 4854435 4856003 R Residues 9 to 506 of 522 are 28.96 pct identical to residues 14 to 499 of 516 from MG1655 : b1487; hypothetical protein complement(4854435..4856003) Escherichia coli CFT073 1038557 NP_756934.1 CDS fdhF NC_004431.1 4856378 4858525 R Escherichia coli K-12 ortholog: b4079; Escherichia coli O157:H7 ortholog: z5678; formate dehydrogenase H complement(4856378..4858525) Escherichia coli CFT073 1038553 NP_756935.1 CDS c5083 NC_004431.1 4858103 4858489 D hypothetical protein 4858103..4858489 Escherichia coli CFT073 1038551 NP_756936.1 CDS yjcP NC_004431.1 4858723 4860189 R part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; outer membrane efflux protein MdtP complement(4858723..4860189) Escherichia coli CFT073 1038549 NP_756937.1 CDS yjcQ NC_004431.1 4860186 4862237 R possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO complement(4860186..4862237) Escherichia coli CFT073 1038545 NP_756938.1 CDS yjcR NC_004431.1 4862237 4863268 R with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN complement(4862237..4863268) Escherichia coli CFT073 1038544 NP_756939.1 CDS c5088 NC_004431.1 4863287 4863610 R Residues 17 to 107 of 107 are 95.60 pct identical to residues 1 to 91 of 91 from GenPept.129 : >dbj|BAB38488.1| (AP002568) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein complement(4863287..4863610) Escherichia coli CFT073 1038520 NP_756940.1 CDS yjcS NC_004431.1 4863771 4865768 R Escherichia coli K-12 ortholog: b4083; Escherichia coli O157:H7 ortholog: z5683; hypothetical protein complement(4863771..4865768) Escherichia coli CFT073 1038518 NP_756941.1 CDS yjcT NC_004431.1 4866029 4866958 R Escherichia coli K-12 ortholog: b4084; D-allose kinase complement(4866029..4866958) Escherichia coli CFT073 1038491 NP_756942.1 CDS yjcU NC_004431.1 4866942 4867643 R Escherichia coli K-12 ortholog: b4085; allulose-6-phosphate 3-epimerase complement(4866942..4867643) Escherichia coli CFT073 1038475 NP_756943.1 CDS yjcV NC_004431.1 4867648 4868628 R Escherichia coli K-12 ortholog: b4086; Escherichia coli O157:H7 ortholog: z5251; D-allose transporter subunit complement(4867648..4868628) Escherichia coli CFT073 1038473 NP_756944.1 CDS yjcW NC_004431.1 4868607 4870139 R with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains; D-allose transporter ATP-binding protein complement(4868607..4870139) Escherichia coli CFT073 1038396 NP_756945.1 CDS yjcX NC_004431.1 4870266 4871207 R ALBP; Escherichia coli K-12 ortholog: b4088; D-allose transporter subunit complement(4870266..4871207) Escherichia coli CFT073 1038350 NP_756946.2 CDS rpiR NC_004431.1 4871260 4872150 R involved in rpiB and als operon repression; DNA-binding transcriptional repressor RpiR complement(4871260..4872150) Escherichia coli CFT073 1038300 NP_756947.1 CDS rpiB NC_004431.1 4872509 4872958 D catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 4872509..4872958 Escherichia coli CFT073 1038252 NP_756948.1 CDS c5097 NC_004431.1 4873027 4873356 D Escherichia coli O157:H7 ortholog: z5694; hypothetical protein 4873027..4873356 Escherichia coli CFT073 1038212 NP_756949.1 CDS phnP NC_004431.1 4873384 4874142 R required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein complement(4873384..4874142) Escherichia coli CFT073 1038195 NP_756950.1 CDS phnO NC_004431.1 4874144 4874578 R PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role; aminoalkylphosphonic acid N-acetyltransferase complement(4874144..4874578) Escherichia coli CFT073 1038175 NP_756951.1 CDS phnM NC_004431.1 4875122 4876258 R Escherichia coli K-12 ortholog: b4095; Escherichia coli O157:H7 ortholog: z5698; PhnM protein complement(4875122..4876258) Escherichia coli CFT073 1038171 NP_756952.1 CDS phnL NC_004431.1 4876255 4876935 R Escherichia coli K-12 ortholog: b4096; Escherichia coli O157:H7 ortholog: z5699; phosphonate ABC transporter ATP-binding protein complement(4876255..4876935) Escherichia coli CFT073 1038082 NP_756953.2 CDS phnK NC_004431.1 4877046 4877804 R Escherichia coli K-12 ortholog: b4097; Escherichia coli O157:H7 ortholog: z5700; phosphonate C-P lyase system protein PhnK complement(4877046..4877804) Escherichia coli CFT073 1038045 NP_756954.1 CDS phnJ NC_004431.1 4877801 4878730 R Escherichia coli K-12 ortholog: b4098; Escherichia coli O157:H7 ortholog: z5701; PhnJ protein complement(4877801..4878730) Escherichia coli CFT073 1038043 NP_756955.1 CDS phnI NC_004431.1 4878639 4879709 R Escherichia coli K-12 ortholog: b4099; Escherichia coli O157:H7 ortholog: z5702; PhnI protein complement(4878639..4879709) Escherichia coli CFT073 1038042 NP_756956.1 CDS phnH NC_004431.1 4879703 4880287 R Escherichia coli K-12 ortholog: b4100; Escherichia coli O157:H7 ortholog: z5703; carbon-phosphorus lyase complex subunit complement(4879703..4880287) Escherichia coli CFT073 1038039 NP_756957.1 CDS phnG NC_004431.1 4880284 4880736 R Escherichia coli K-12 ortholog: b4101; Escherichia coli O157:H7 ortholog: z5704; PhnG protein complement(4880284..4880736) Escherichia coli CFT073 1038038 NP_756958.1 CDS phnF NC_004431.1 4880737 4881471 R may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF complement(4880737..4881471) Escherichia coli CFT073 1038037 NP_756959.1 CDS phnE NC_004431.1 4881483 4882325 R Escherichia coli O157:H7 ortholog: z5706; membrane channel protein component of Pn transporter complement(4881483..4882325) Escherichia coli CFT073 1038031 NP_756960.1 CDS phnD NC_004431.1 4882368 4883384 R Escherichia coli K-12 ortholog: b4105; Escherichia coli O157:H7 ortholog: z5707; phosphonates-binding periplasmic protein complement(4882368..4883384) Escherichia coli CFT073 1038026 NP_756961.1 CDS phnC NC_004431.1 4883409 4884197 R Escherichia coli K-12 ortholog: b4106; Escherichia coli O157:H7 ortholog: z5708; phosphonate/organophosphate ester transporter subunit complement(4883409..4884197) Escherichia coli CFT073 1038016 NP_756962.1 CDS phnB NC_004431.1 4884330 4884773 R Escherichia coli K-12 ortholog: b4107; Escherichia coli O157:H7 ortholog: z5709; hypothetical protein complement(4884330..4884773) Escherichia coli CFT073 1037984 NP_756963.1 CDS phnA NC_004431.1 4884933 4885415 R Escherichia coli K-12 ortholog: b4108; Escherichia coli O157:H7 ortholog: z5710; PhnA protein complement(4884933..4885415) Escherichia coli CFT073 1037973 NP_756964.1 CDS yjdA NC_004431.1 4885671 4887899 D Escherichia coli K-12 ortholog: b4109; Escherichia coli O157:H7 ortholog: z5711; hypothetical protein 4885671..4887899 Escherichia coli CFT073 1037942 NP_756965.1 CDS yjcZ NC_004431.1 4887896 4888774 D Escherichia coli K-12 ortholog: b4110; Escherichia coli O157:H7 ortholog: z5712; hypothetical protein 4887896..4888774 Escherichia coli CFT073 1037941 NP_756966.1 CDS proP NC_004431.1 4889005 4890540 D Proline porter II; Escherichia coli K-12 ortholog: b4111; Escherichia coli O157:H7 ortholog: z5713; proline/glycine betaine transporter 4889005..4890540 Escherichia coli CFT073 1037931 NP_756967.1 CDS basS NC_004431.1 4890717 4891817 R Escherichia coli K-12 ortholog: b4112; Escherichia coli O157:H7 ortholog: z5714; sensor protein BasS/PmrB complement(4890717..4891817) Escherichia coli CFT073 1037924 NP_756968.1 CDS basR NC_004431.1 4891818 4892486 R response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR complement(4891818..4892486) Escherichia coli CFT073 1037919 NP_756969.2 CDS yjdB NC_004431.1 4892483 4894156 R with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; cell division protein complement(4892483..4894156) Escherichia coli CFT073 1037911 NP_756970.1 CDS yjdE NC_004431.1 4894230 4895567 R Escherichia coli K-12 ortholog: b4115; Escherichia coli O157:H7 ortholog: z5717; arginine:agmatin antiporter complement(4894230..4895567) Escherichia coli CFT073 1037910 NP_756971.1 CDS adiY NC_004431.1 4895704 4896465 R Escherichia coli K-12 ortholog: b4116; Escherichia coli O157:H7 ortholog: z5718; regulatory protein adiY complement(4895704..4896465) Escherichia coli CFT073 1037907 NP_756972.1 CDS adiA NC_004431.1 4896801 4899071 R Escherichia coli K-12 ortholog: b4117; Escherichia coli O157:H7 ortholog: z5719; biodegradative arginine decarboxylase complement(4896801..4899071) Escherichia coli CFT073 1037903 NP_756973.1 CDS melR NC_004431.1 4899267 4900175 R Escherichia coli K-12 ortholog: b4118; Escherichia coli O157:H7 ortholog: z5720; DNA-binding transcriptional regulator MelR complement(4899267..4900175) Escherichia coli CFT073 1037902 NP_756974.1 CDS melA NC_004431.1 4900458 4901813 D Escherichia coli K-12 ortholog: b4119; Escherichia coli O157:H7 ortholog: z5721; alpha-galactosidase 4900458..4901813 Escherichia coli CFT073 1037886 NP_756975.1 CDS fumB NC_004431.1 4902575 4904221 R Escherichia coli K-12 ortholog: b4122; Escherichia coli O157:H7 ortholog: z5724; fumarate hydratase class I, anaerobic complement(4902575..4904221) Escherichia coli CFT073 1037869 NP_756976.1 CDS dcuB NC_004431.1 4904299 4905639 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter complement(4904299..4905639) Escherichia coli CFT073 1037862 NP_756977.1 CDS c5129 NC_004431.1 4905707 4905865 D hypothetical protein 4905707..4905865 Escherichia coli CFT073 1037775 NP_756978.1 CDS yjdG NC_004431.1 4906210 4906929 R response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DNA-binding transcriptional activator DcuR complement(4906210..4906929) Escherichia coli CFT073 1037751 NP_756979.1 CDS yjdH NC_004431.1 4906926 4908557 R C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS complement(4906926..4908557) Escherichia coli CFT073 1037750 NP_756980.1 CDS c5132 NC_004431.1 4908549 4908683 D hypothetical protein 4908549..4908683 Escherichia coli CFT073 1037721 NP_756981.1 CDS yjdI NC_004431.1 4908738 4908968 D Escherichia coli K-12 ortholog: b4126; Escherichia coli O157:H7 ortholog: z5728; hypothetical protein 4908738..4908968 Escherichia coli CFT073 1037716 NP_756982.1 CDS yjdJ NC_004431.1 4908980 4909252 D Escherichia coli K-12 ortholog: b4127; Escherichia coli O157:H7 ortholog: z5729; hypothetical protein 4908980..4909252 Escherichia coli CFT073 1037704 NP_756983.1 CDS c5135 NC_004431.1 4909009 4909461 R hypothetical protein complement(4909009..4909461) Escherichia coli CFT073 1037701 NP_756984.1 CDS c5136 NC_004431.1 4909805 4909978 D Escherichia coli K-12 ortholog: b1445; Escherichia coli O157:H7 ortholog: z5731; hypothetical protein 4909805..4909978 Escherichia coli CFT073 1037700 NP_756985.1 CDS c5137 NC_004431.1 4909988 4910131 D hypothetical protein 4909988..4910131 Escherichia coli CFT073 1037696 NP_756986.2 CDS lysS NC_004431.1 4910097 4911614 R class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(4910097..4911614) Escherichia coli CFT073 1037694 NP_756987.1 CDS yjdL NC_004431.1 4911851 4913308 R Escherichia coli K-12 ortholog: b4130; Escherichia coli O157:H7 ortholog: z5733; transporter YjdL complement(4911851..4913308) Escherichia coli CFT073 1037691 NP_756988.1 CDS cadA NC_004431.1 4913367 4915520 R Escherichia coli K-12 ortholog: b4131; Escherichia coli O157:H7 ortholog: z5734; lysine decarboxylase, inducible complement(4913367..4915520) Escherichia coli CFT073 1037690 NP_756989.1 CDS cadB NC_004431.1 4915594 4916928 R antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter complement(4915594..4916928) Escherichia coli CFT073 1037689 NP_756990.1 CDS cadC NC_004431.1 4917294 4918832 R regulates the cadBA operon; DNA-binding transcriptional activator CadC complement(4917294..4918832) Escherichia coli CFT073 1037687 NP_756991.1 CDS c5143 NC_004431.1 4919569 4919811 R Residues 1 to 80 of 80 are 100.00 pct identical to residues 1 to 80 of 80 from GenPept.129 : >gb|AAL67384.1|AF447814_52 (AF447814) L0012-like protein [Escherichia coli]; hypothetical protein complement(4919569..4919811) Escherichia coli CFT073 1037686 NP_756992.1 CDS c5144 NC_004431.1 4920004 4921503 D Residues 7 to 492 of 499 are 40.77 pct identical to residues 10 to 495 of 504 from SwissProt.40 : >sp|P55501|Y4JA_RHISN HYPOTHETICAL 57.2 KD PROTEIN Y4JA/Y4NE/Y4SE; hypothetical protein 4920004..4921503 Escherichia coli CFT073 1037685 NP_756993.1 CDS c5145 NC_004431.1 4921500 4922255 D Residues 1 to 244 of 251 are 41.60 pct identical to residues 1 to 250 of 298 from SwissProt.40 : >sp|P55500|Y4IQ_RHISN INSERTION SEQUENCE ATP-BINDING PROTEIN Y4IQ/Y4ND/Y4SD; hypothetical protein 4921500..4922255 Escherichia coli CFT073 1037683 NP_756994.1 CDS c5146 NC_004431.1 4922315 4922839 R Escherichia coli O157:H7 ortholog: z1664; hypothetical protein complement(4922315..4922839) Escherichia coli CFT073 1037682 NP_756995.1 CDS c5147 NC_004431.1 4922924 4923121 R Escherichia coli O157:H7 ortholog: z1663; hypothetical protein complement(4922924..4923121) Escherichia coli CFT073 1037681 NP_756996.1 CDS c5148 NC_004431.1 4923133 4923621 R Escherichia coli O157:H7 ortholog: z5092; hypothetical protein complement(4923133..4923621) Escherichia coli CFT073 1037680 NP_756997.1 CDS c5149 NC_004431.1 4923618 4923995 R Escherichia coli K-12 ortholog: b2005; Escherichia coli O157:H7 ortholog: z5091; hypothetical protein complement(4923618..4923995) Escherichia coli CFT073 1037679 NP_756998.1 CDS c5150 NC_004431.1 4924085 4924513 R Escherichia coli K-12 ortholog: b2004; Escherichia coli O157:H7 ortholog: z3164; hypothetical protein complement(4924085..4924513) Escherichia coli CFT073 1037677 NP_756999.1 CDS c5151 NC_004431.1 4924532 4924753 R Escherichia coli K-12 ortholog: b2003; Escherichia coli O157:H7 ortholog: z1218; hypothetical protein complement(4924532..4924753) Escherichia coli CFT073 1037676 NP_757000.1 CDS c5152 NC_004431.1 4924822 4925298 R Escherichia coli K-12 ortholog: b2002; Escherichia coli O157:H7 ortholog: z1217; radC-like protein yeeS complement(4924822..4925298) Escherichia coli CFT073 1037675 NP_757001.1 CDS c5153 NC_004431.1 4924834 4925364 D Residues 1 to 156 of 176 are 91.02 pct identical to residues 1 to 156 of 319 from GenPept.129 : >gb|AAL67347.1|AF447814_15 (AF447814) unknown [Escherichia coli]; hypothetical protein 4924834..4925364 Escherichia coli CFT073 1037672 NP_757002.1 CDS c5154 NC_004431.1 4925298 4925744 D Residues 6 to 143 of 148 are 86.95 pct identical to residues 161 to 298 of 319 from GenPept.129 : >gb|AAL67347.1|AF447814_15 (AF447814) unknown [Escherichia coli]; hypothetical protein 4925298..4925744 Escherichia coli CFT073 1037671 NP_757003.1 CDS c5155 NC_004431.1 4925313 4925798 R Escherichia coli K-12 ortholog: b2643; Escherichia coli O157:H7 ortholog: z1656; hypothetical protein complement(4925313..4925798) Escherichia coli CFT073 1037670 NP_757004.1 CDS c5156 NC_004431.1 4925889 4926707 R Escherichia coli K-12 ortholog: b0252; Escherichia coli O157:H7 ortholog: z1655; hypothetical protein complement(4925889..4926707) Escherichia coli CFT073 1037669 NP_757005.1 CDS c5157 NC_004431.1 4926797 4927030 R Escherichia coli K-12 ortholog: b0249; hypothetical protein complement(4926797..4927030) Escherichia coli CFT073 1037667 NP_757006.1 CDS c5158 NC_004431.1 4927036 4927818 R Residues 1 to 161 of 260 are 100.00 pct identical to residues 1 to 161 of 260 from GenPept.129 : >gb|AAL67392.1|AF447814_60 (AF447814) intergenic-region protein [Escherichia coli]; hypothetical protein complement(4927036..4927818) Escherichia coli CFT073 1037663 NP_757007.1 CDS c5159 NC_004431.1 4927846 4927977 D hypothetical protein 4927846..4927977 Escherichia coli CFT073 1037662 NP_757008.1 CDS c5160 NC_004431.1 4927861 4928541 R Escherichia coli K-12 ortholog: b2634; transcriptional regulator YfjR complement(4927861..4928541) Escherichia coli CFT073 1037659 NP_757009.1 CDS c5161 NC_004431.1 4928570 4928725 R hypothetical protein complement(4928570..4928725) Escherichia coli CFT073 1037657 NP_757010.1 CDS c5162 NC_004431.1 4928744 4929628 R Residues 12 to 294 of 294 are 35.33 pct identical to residues 12 to 289 of 289 from MG1655 : b2632; hypothetical protein complement(4928744..4929628) Escherichia coli CFT073 1037655 NP_757011.1 CDS c5163 NC_004431.1 4929731 4930684 D Residues 2 to 317 of 317 are 100.00 pct identical to residues 1 to 316 of 316 from GenPept.129 : >gb|AAL67396.1|AF447814_64 (AF447814) unknown [Escherichia coli]; hypothetical protein 4929731..4930684 Escherichia coli CFT073 1037654 NP_757012.1 CDS c5164 NC_004431.1 4930681 4931556 R Residues 30 to 274 of 291 are 100.00 pct identical to residues 1 to 245 of 254 from GenPept.129 : >gb|AAL67397.1|AF447814_65 (AF447814) unknown [Escherichia coli]; hypothetical protein complement(4930681..4931556) Escherichia coli CFT073 1037653 NP_757013.1 CDS c5165 NC_004431.1 4930708 4930890 D hypothetical protein 4930708..4930890 Escherichia coli CFT073 1037652 NP_757014.1 CDS c5166 NC_004431.1 4931923 4932141 R Escherichia coli O157:H7 ortholog: z1647; partial transposase complement(4931923..4932141) Escherichia coli CFT073 1037651 NP_757015.1 CDS c5167 NC_004431.1 4932138 4932815 R Escherichia coli O157:H7 ortholog: z3297; transposase IS629 complement(4932138..4932815) Escherichia coli CFT073 1037648 NP_757016.1 CDS c5168 NC_004431.1 4932812 4933138 R Escherichia coli O157:H7 ortholog: z2982; hypothetical protein complement(4932812..4933138) Escherichia coli CFT073 1037647 NP_757017.1 CDS c5169 NC_004431.1 4933881 4934117 D Residues 1 to 78 of 78 are 100.00 pct identical to residues 1 to 78 of 78 from GenPept.129 : >gb|AAL67400.1|AF447814_68 (AF447814) unknown [Escherichia coli]; hypothetical protein 4933881..4934117 Escherichia coli CFT073 1037645 NP_757018.1 CDS c5170 NC_004431.1 4934123 4934371 R hypothetical protein complement(4934123..4934371) Escherichia coli CFT073 1037642 NP_757019.1 CDS c5171 NC_004431.1 4934166 4934432 D hypothetical protein 4934166..4934432 Escherichia coli CFT073 1037640 NP_757020.1 CDS c5172 NC_004431.1 4934476 4935216 D Residues 1 to 246 of 246 are 100.00 pct identical to residues 1 to 246 of 246 from GenPept.129 : >gb|AAL67401.1|AF447814_69 (AF447814) intergenic-region protein [Escherichia coli]; hypothetical protein 4934476..4935216 Escherichia coli CFT073 1037639 NP_757021.1 CDS c5173 NC_004431.1 4935304 4935522 D hypothetical protein 4935304..4935522 Escherichia coli CFT073 1037631 NP_757022.1 CDS c5174 NC_004431.1 4935990 4938038 D iron-responsive element (ireA); ireA gene is located on pathogenicity island I (PAI I); outer membrane protein; iron-regulated outer membrane virulence protein 4935990..4938038 Escherichia coli CFT073 1037614 NP_757023.1 CDS c5175 NC_004431.1 4938218 4938349 R Residues 1 to 43 of 43 are 88.37 pct identical to residues 358 to 400 of 400 from GenPept.129 : >gb|AAK69271.1|AF336309_66 (AF336309) unknown [Yersinia enterocolitica]; hypothetical protein complement(4938218..4938349) Escherichia coli CFT073 1037609 NP_757024.1 CDS c5176 NC_004431.1 4938378 4939160 R Escherichia coli O157:H7 ortholog: z2082; transposase complement(4938378..4939160) Escherichia coli CFT073 1037605 NP_757025.1 CDS c5177 NC_004431.1 4939432 4939758 D Escherichia coli O157:H7 ortholog: z5879; hypothetical protein 4939432..4939758 Escherichia coli CFT073 1037596 NP_757026.1 CDS c5178 NC_004431.1 4939758 4940645 D Escherichia coli O157:H7 ortholog: z3297; transposase IS629 4939758..4940645 Escherichia coli CFT073 1037595 NP_757027.1 CDS papG_2 NC_004431.1 4940831 4941841 R Residues 1 to 336 of 336 are 56.72 pct identical to residues 1 to 335 of 335 from SwissProt.40 : >sp|P42188|PRSG_ECOLI FIMBRIAL PROTEIN PRSG PRECURSOR (ADHESIN); PapG protein complement(4940831..4941841) Escherichia coli CFT073 1037594 NP_757028.1 CDS papF_2 NC_004431.1 4941885 4942415 R Residues 11 to 176 of 176 are 92.81 pct identical to residues 1 to 167 of 167 from SwissProt.40 : >sp|P42187|PRSF_ECOLI MINOR FIMBRIAL PROTEIN PRSF PRECURSOR; PapF protein complement(4941885..4942415) Escherichia coli CFT073 1037591 NP_757029.1 CDS papE_2 NC_004431.1 4942460 4942999 R Residues 7 to 179 of 179 are 91.32 pct identical to residues 1 to 173 of 173 from SwissProt.40 : >sp|P08407|PAPE_ECOLI FIMBRIAL PROTEIN PAPE PRECURSOR; PapE protein complement(4942460..4942999) Escherichia coli CFT073 1037587 NP_757030.1 CDS papK_2 NC_004431.1 4943008 4943547 R Residues 2 to 179 of 179 are 100.00 pct identical to residues 1 to 178 of 178 from SwissProt.40 : >sp|P42190|PAPK_ECOLI PROTEIN PAPK PRECURSOR; PapK protein complement(4943008..4943547) Escherichia coli CFT073 1037585 NP_757031.1 CDS c5183 NC_004431.1 4943153 4943767 D hypothetical protein 4943153..4943767 Escherichia coli CFT073 1037584 NP_757032.1 CDS papJ_2 NC_004431.1 4943554 4944135 R Residues 1 to 193 of 193 are 96.37 pct identical to residues 1 to 193 of 193 from SwissProt.40 : >sp|P42189|PRSJ_ECOLI PRSJ PROTEIN PRECURSOR; PapJ protein complement(4943554..4944135) Escherichia coli CFT073 1037582 NP_757033.1 CDS papD_2 NC_004431.1 4944172 4944906 R Residues 3 to 244 of 244 are 40.74 pct identical to residues 9 to 246 of 250 from MG1655 : b2336; PapD protein complement(4944172..4944906) Escherichia coli CFT073 1037581 NP_757034.1 CDS papC_2 NC_004431.1 4944977 4947508 R Residues 8 to 839 of 843 are 43.20 pct identical to residues 1 to 842 of 879 from EDL933 : z3600; PapC protein complement(4944977..4947508) Escherichia coli CFT073 1037579 NP_757035.1 CDS papH_2 NC_004431.1 4947546 4948133 R Residues 1 to 195 of 195 are 98.97 pct identical to residues 1 to 195 of 195 from SwissProt.40 : >sp|P42185|PRSH_ECOLI PRS FIMBRIAL MINOR PILIN PROTEIN PRECURSOR; PapH protein complement(4947546..4948133) Escherichia coli CFT073 1037577 NP_757036.1 CDS papA_2 NC_004431.1 4948203 4948799 R Residues 12 to 198 of 198 are 99.46 pct identical to residues 1 to 187 of 187 from SwissProt.40 : >sp|P04740|FMK1_ECOLI KS71A FIMBRILLIN PRECURSOR (P-FIMBRIAL ANTIGEN); PapA protein complement(4948203..4948799) Escherichia coli CFT073 1037576 NP_757037.1 CDS papI_2 NC_004431.1 4949723 4949944 D Residues 1 to 73 of 73 are 100.00 pct identical to residues 5 to 77 of 77 from SwissProt.40 : >sp|P25395|KS7A_ECOLI P FIMBRIAL REGULATORY PROTEIN KS71A; PapI protein 4949723..4949944 Escherichia coli CFT073 1037573 NP_757038.1 CDS c5190 NC_004431.1 4949967 4950092 R hypothetical protein complement(4949967..4950092) Escherichia coli CFT073 1037572 NP_757039.1 CDS c5191 NC_004431.1 4950188 4950634 D Residues 1 to 148 of 148 are 100.00 pct identical to residues 1 to 148 of 148 from GenPept.129 : >gb|AAL67420.1|AF447814_88 (AF447814) unknown [Escherichia coli]; hypothetical protein 4950188..4950634 Escherichia coli CFT073 1037570 NP_757040.1 CDS c5192 NC_004431.1 4950287 4950520 R Escherichia coli O157:H7 ortholog: z1627; hypothetical protein complement(4950287..4950520) Escherichia coli CFT073 1037568 NP_757041.1 CDS c5193 NC_004431.1 4950589 4951305 R Residues 89 to 238 of 238 are 100.00 pct identical to residues 30 to 179 of 179 from GenPept.129 : >gb|AAL67421.1|AF447814_89 (AF447814) unknown [Escherichia coli]; hypothetical protein complement(4950589..4951305) Escherichia coli CFT073 1037567 NP_757042.1 CDS c5194 NC_004431.1 4951420 4951572 R hypothetical protein complement(4951420..4951572) Escherichia coli CFT073 1037561 NP_757043.1 CDS c5195 NC_004431.1 4951662 4951988 R Residues 4 to 102 of 108 are 32.32 pct identical to residues 7 to 103 of 197 from GenPept.129 : >gb|AAL08430.1|AF326777_5 (AF326777) unknown [Shigella flexneri 2a]; hypothetical protein complement(4951662..4951988) Escherichia coli CFT073 1037560 NP_757044.1 CDS c5196 NC_004431.1 4952414 4952704 D Escherichia coli K-12 ortholog: b1997; transposase insC 4952414..4952704 Escherichia coli CFT073 1037559 NP_757045.1 CDS c5197 NC_004431.1 4952728 4953375 D Escherichia coli K-12 ortholog: b4273; Escherichia coli O157:H7 ortholog: z1825; transposase insD 4952728..4953375 Escherichia coli CFT073 1037557 NP_757046.1 CDS c5198 NC_004431.1 4953372 4953542 D Residues 1 to 56 of 56 are 96.42 pct identical to residues 66 to 121 of 121 from GenPept.129 : >gb|AAG54583.1|AE005203_12 (AE005203) unknown protein encoded by IS2 [Escherichia coli O157:H7 EDL933]; hypothetical protein 4953372..4953542 Escherichia coli CFT073 1037556 NP_757047.1 CDS c5199 NC_004431.1 4953577 4953954 R hypothetical protein complement(4953577..4953954) Escherichia coli CFT073 1037555 NP_757048.1 CDS c5200 NC_004431.1 4953819 4953944 D hypothetical protein 4953819..4953944 Escherichia coli CFT073 1037554 NP_757049.1 CDS pgtP NC_004431.1 4953985 4955349 R Residues 1 to 406 of 454 are 89.16 pct identical to residues 1 to 405 of 406 from SwissProt.40 : >sp|P12681|PGTP_SALTY Phosphoglycerate transporter protein; transporter protein complement(4953985..4955349) Escherichia coli CFT073 1037552 NP_757050.1 CDS pgtC NC_004431.1 4955658 4956965 D Residues 41 to 435 of 435 are 78.48 pct identical to residues 3 to 397 of 397 from SwissProt.40 : >sp|P37591|PGTC_SALTY PHOSPHOGLYCERATE TRANSPORT REGULATORY PROTEIN PGTC PRECURSOR; regulatory protein 4955658..4956965 Escherichia coli CFT073 1037551 NP_757051.1 CDS pgtB NC_004431.1 4956962 4958971 D Residues 139 to 669 of 669 are 79.28 pct identical to residues 63 to 593 of 593 from SwissProt.40 : >sp|P37433|PGTB_SALTY PHOSPHOGLYCERATE TRANSPORT SYSTEM SENSOR PROTEIN PGTB; regulatory protein 4956962..4958971 Escherichia coli CFT073 1037550 NP_757052.1 CDS pgtA NC_004431.1 4958952 4960208 D Residues 4 to 417 of 418 are 79.95 pct identical to residues 1 to 414 of 415 from SwissProt.40 : >sp|P06184|PGTA_SALTY PHOSPHOGLYCERATE TRANSPORT SYSTEM TRANSCRIPTIONAL REGULATORY PROTEIN PGTA; transport activator 4958952..4960208 Escherichia coli CFT073 1037549 NP_757053.1 CDS c5205 NC_004431.1 4961189 4961833 R Escherichia coli O157:H7 ortholog: z1645; hypothetical protein complement(4961189..4961833) Escherichia coli CFT073 1037548 NP_757054.1 CDS c5206 NC_004431.1 4961854 4962162 R Residues 14 to 102 of 102 are 95.50 pct identical to residues 1 to 89 of 89 from GenPept.129 : >dbj|BAB34811.1| (AP002554) transcriptional regulator [Escherichia coli O157:H7]; hypothetical protein complement(4961854..4962162) Escherichia coli CFT073 1037547 NP_757055.1 CDS c5207 NC_004431.1 4962202 4962357 R Residues 19 to 51 of 51 are 100.00 pct identical to residues 180 to 212 of 212 from GenPept.129 : >gb|AAG55759.1|AE005312_5 (AE005312) unknown [Escherichia coli O157:H7 EDL933]; hypothetical protein complement(4962202..4962357) Escherichia coli CFT073 1037546 NP_757056.1 CDS c5208 NC_004431.1 4962284 4962847 R Escherichia coli K-12 ortholog: b0601; Escherichia coli O157:H7 ortholog: z1644; hypothetical protein complement(4962284..4962847) Escherichia coli CFT073 1037545 NP_757057.1 CDS c5209 NC_004431.1 4962832 4964064 R Escherichia coli K-12 ortholog: b0602; Escherichia coli O157:H7 ortholog: z1643; hypothetical protein complement(4962832..4964064) Escherichia coli CFT073 1037544 NP_757058.1 CDS c5210 NC_004431.1 4964200 4964853 R hypothetical protein complement(4964200..4964853) Escherichia coli CFT073 1037543 NP_757059.1 CDS c5211 NC_004431.1 4965038 4966498 R hypothetical protein complement(4965038..4966498) Escherichia coli CFT073 1037542 NP_757060.1 CDS c5212 NC_004431.1 4965775 4965957 D hypothetical protein 4965775..4965957 Escherichia coli CFT073 1037541 NP_757061.1 CDS c5213 NC_004431.1 4966657 4967547 R Escherichia coli O157:H7 ortholog: z3297; transposase IS629 complement(4966657..4967547) Escherichia coli CFT073 1037540 NP_757062.1 CDS c5214 NC_004431.1 4967544 4967870 R Escherichia coli O157:H7 ortholog: z2982; hypothetical protein complement(4967544..4967870) Escherichia coli CFT073 1037539 NP_757063.1 CDS c5215 NC_004431.1 4967922 4969685 R Residues 5 to 587 of 587 are 96.39 pct identical to residues 1 to 583 of 774 from GenPept.129 : >gb|AAK00457.1| (AF200692) unknown [Shigella flexneri 2a]; hypothetical protein complement(4967922..4969685) Escherichia coli CFT073 1037538 NP_757064.1 CDS c5216 NC_004431.1 4970125 4971387 R Int(P4); Escherichia coli K-12 ortholog: b4271; Escherichia coli O157:H7 ortholog: z4313; prophage P4 integrase complement(4970125..4971387) Escherichia coli CFT073 1037536 NP_757065.1 CDS yjdC NC_004431.1 4971767 4972366 R Escherichia coli K-12 ortholog: b4135; Escherichia coli O157:H7 ortholog: z5740; transcriptional regulator complement(4971767..4972366) Escherichia coli CFT073 1037533 NP_757066.1 CDS dipZ NC_004431.1 4972379 4974076 R two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein complement(4972379..4974076) Escherichia coli CFT073 1037532 NP_757067.2 CDS cutA NC_004431.1 4974052 4974390 R copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA complement(4974052..4974390) Escherichia coli CFT073 1037531 NP_757068.1 CDS dcuA NC_004431.1 4974506 4975807 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter complement(4974506..4975807) Escherichia coli CFT073 1037530 NP_757069.1 CDS c5221 NC_004431.1 4975907 4977358 D Residues 349 to 483 of 483 are 100.00 pct identical to residues 1 to 135 of 135 from GenPept.129 : >emb|CAA26174.1| (X02307) URF 4 [Escherichia coli]; hypothetical protein 4975907..4977358 Escherichia coli CFT073 1037529 NP_757070.1 CDS aspA NC_004431.1 4975925 4977406 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(4975925..4977406) Escherichia coli CFT073 1037528 NP_757071.1 CDS fxsA NC_004431.1 4977698 4978174 D F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA 4977698..4978174 Escherichia coli CFT073 1037526 NP_757072.2 CDS yjeH NC_004431.1 4978190 4979446 R uncharacterized member of the APC superfamily of amino acid transporters; unknown function; hypothetical protein complement(4978190..4979446) Escherichia coli CFT073 1037525 NP_757073.1 CDS c5225 NC_004431.1 4979719 4980036 R hypothetical protein complement(4979719..4980036) Escherichia coli CFT073 1037524 NP_757074.1 CDS groES NC_004431.1 4979722 4980015 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 4979722..4980015 Escherichia coli CFT073 1037523 NP_757075.1 CDS groEL NC_004431.1 4980059 4981705 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 4980059..4981705 Escherichia coli CFT073 1037522 NP_757076.1 CDS yjeI NC_004431.1 4981810 4982196 D Escherichia coli K-12 ortholog: b4144; Escherichia coli O157:H7 ortholog: z5749; hypothetical protein 4981810..4982196 Escherichia coli CFT073 1037521 NP_757077.1 CDS c5229 NC_004431.1 4981882 4982286 R hypothetical protein complement(4981882..4982286) Escherichia coli CFT073 1037520 NP_757078.1 CDS yjeJ NC_004431.1 4982246 4983115 R Escherichia coli K-12 ortholog: b4145; Escherichia coli O157:H7 ortholog: z5750; hypothetical protein complement(4982246..4983115) Escherichia coli CFT073 1037519 NP_757079.1 CDS yjeK NC_004431.1 4983350 4984378 R Escherichia coli K-12 ortholog: b4146; Escherichia coli O157:H7 ortholog: z5751; hypothetical protein complement(4983350..4984378) Escherichia coli CFT073 1037518 NP_757080.1 CDS efp NC_004431.1 4984420 4984986 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 4984420..4984986 Escherichia coli CFT073 1037517 NP_757081.1 CDS c5233 NC_004431.1 4984468 4985022 R hypothetical protein complement(4984468..4985022) Escherichia coli CFT073 1037516 NP_757082.1 CDS ecnA NC_004431.1 4985038 4985163 D acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex; entericidin A 4985038..4985163 Escherichia coli CFT073 1037515 NP_757083.1 CDS ecnB NC_004431.1 4985274 4985420 D Escherichia coli O157:H7 ortholog: z5754; entericidin B 4985274..4985420 Escherichia coli CFT073 1037514 NP_757084.1 CDS sugE NC_004431.1 4985446 4985913 D Escherichia coli K-12 ortholog: b4148; Escherichia coli O157:H7 ortholog: z5755; SugE protein 4985446..4985913 Escherichia coli CFT073 1037513 NP_757085.1 CDS blc NC_004431.1 4985910 4986443 R lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc complement(4985910..4986443) Escherichia coli CFT073 1037512 NP_757086.2 CDS ampC NC_004431.1 4986532 4987665 R Escherichia coli K-12 ortholog: b4150; Escherichia coli O157:H7 ortholog: z5757; beta-lactamase complement(4986532..4987665) Escherichia coli CFT073 1037511 NP_757087.1 CDS frdD NC_004431.1 4987728 4988117 R in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D complement(4987728..4988117) Escherichia coli CFT073 1037510 NP_757088.1 CDS frdC NC_004431.1 4988098 4988493 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C complement(4988098..4988493) Escherichia coli CFT073 1037509 NP_757089.1 CDS frdB NC_004431.1 4988504 4989238 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit complement(4988504..4989238) Escherichia coli CFT073 1037508 NP_757090.1 CDS frdA NC_004431.1 4989231 4991039 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(4989231..4991039) Escherichia coli CFT073 1037507 NP_757091.2 CDS yjeA NC_004431.1 4991364 4992341 D lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 4991364..4992341 Escherichia coli CFT073 1037506 NP_757092.1 CDS yjeM NC_004431.1 4992518 4994062 D Escherichia coli K-12 ortholog: b4156; Escherichia coli O157:H7 ortholog: z5764; transporter YjeM 4992518..4994062 Escherichia coli CFT073 1037505 NP_757093.1 CDS yjeP NC_004431.1 4994213 4997536 R Escherichia coli K-12 ortholog: b4159; Escherichia coli O157:H7 ortholog: z5765; hypothetical protein complement(4994213..4997536) Escherichia coli CFT073 1037504 NP_757094.1 CDS c5246 NC_004431.1 4997456 4998481 D hypothetical protein 4997456..4998481 Escherichia coli CFT073 1037503 NP_757095.1 CDS psd NC_004431.1 4997558 4998526 R catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase complement(4997558..4998526) Escherichia coli CFT073 1037502 NP_757096.2 CDS yjeQ NC_004431.1 4998623 4999675 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(4998623..4999675) Escherichia coli CFT073 1037501 NP_757097.2 CDS yjeR NC_004431.1 4999770 5000315 D 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 4999770..5000315 Escherichia coli CFT073 1037500 NP_757098.1 CDS yjeS NC_004431.1 5001094 5002278 R Escherichia coli K-12 ortholog: b4166; Escherichia coli O157:H7 ortholog: z5773; electron transport protein yjeS complement(5001094..5002278) Escherichia coli CFT073 1037495 NP_757099.1 CDS yjeF NC_004431.1 5002211 5003779 D Escherichia coli K-12 ortholog: b4167; Escherichia coli O157:H7 ortholog: z5774; hypothetical protein 5002211..5003779 Escherichia coli CFT073 1037494 NP_757100.1 CDS yjeE NC_004431.1 5003751 5004212 D possibly involved in cell wall synthesis; ATPase 5003751..5004212 Escherichia coli CFT073 1037493 NP_757101.1 CDS amiB NC_004431.1 5004216 5005562 D Escherichia coli K-12 ortholog: b4169; Escherichia coli O157:H7 ortholog: z5776; N-acetylmuramoyl-L-alanine amidase 5004216..5005562 Escherichia coli CFT073 1037492 NP_757102.1 CDS mutL NC_004431.1 5005569 5007419 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 5005569..5007419 Escherichia coli CFT073 1037491 NP_757103.1 CDS miaA NC_004431.1 5007412 5008362 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 5007412..5008362 Escherichia coli CFT073 1037490 NP_757104.1 CDS hfq NC_004431.1 5008448 5008756 D Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 5008448..5008756 Escherichia coli CFT073 1037487 NP_757105.1 CDS hflX NC_004431.1 5008832 5010112 D involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; GTPase HflX 5008832..5010112 Escherichia coli CFT073 1037486 NP_757106.1 CDS hflK NC_004431.1 5010198 5011457 D with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 5010198..5011457 Escherichia coli CFT073 1037485 NP_757107.1 CDS hflC NC_004431.1 5011460 5012464 D with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 5011460..5012464 Escherichia coli CFT073 1037484 NP_757108.1 CDS yjeT NC_004431.1 5012546 5012743 D Escherichia coli K-12 ortholog: b4176; Escherichia coli O157:H7 ortholog: z5783; hypothetical protein 5012546..5012743 Escherichia coli CFT073 1037483 NP_757109.1 CDS purA NC_004431.1 5012847 5014145 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 5012847..5014145 Escherichia coli CFT073 1037482 NP_757110.1 CDS yjeB NC_004431.1 5014350 5014775 D negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 5014350..5014775 Escherichia coli CFT073 1037481 NP_757111.2 CDS vacB NC_004431.1 5014814 5017255 D 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 5014814..5017255 Escherichia coli CFT073 1037480 NP_757112.1 CDS yjfH NC_004431.1 5017346 5018077 D Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 5017346..5018077 Escherichia coli CFT073 1037479 NP_757113.1 CDS yjfI NC_004431.1 5018204 5018605 D Escherichia coli K-12 ortholog: b4181; Escherichia coli O157:H7 ortholog: z5788; hypothetical protein 5018204..5018605 Escherichia coli CFT073 1037478 NP_757114.1 CDS yjfJ NC_004431.1 5018624 5019322 D Escherichia coli K-12 ortholog: b4182; Escherichia coli O157:H7 ortholog: z5789; hypothetical protein 5018624..5019322 Escherichia coli CFT073 1037477 NP_757115.1 CDS yjfK NC_004431.1 5019372 5020031 D Escherichia coli K-12 ortholog: b4183; Escherichia coli O157:H7 ortholog: z5790; hypothetical protein 5019372..5020031 Escherichia coli CFT073 1037476 NP_757116.1 CDS yjfL NC_004431.1 5020049 5020438 D Escherichia coli K-12 ortholog: b4184; Escherichia coli O157:H7 ortholog: z5791; hypothetical protein 5020049..5020438 Escherichia coli CFT073 1037475 NP_757117.1 CDS c5269 NC_004431.1 5020279 5020446 D Residues 23 to 55 of 55 are 90.90 pct identical to residues 100 to 132 of 132 from GenPept.129 : >gb|AAG59380.1|AE005651_9 (AE005651) yjfL gene product [Escherichia coli O157:H7 EDL933]; hypothetical protein 5020279..5020446 Escherichia coli CFT073 1037472 NP_757118.1 CDS c5270 NC_004431.1 5020333 5020500 R hypothetical protein complement(5020333..5020500) Escherichia coli CFT073 1037471 NP_757119.1 CDS c5271 NC_004431.1 5020365 5020517 R hypothetical protein complement(5020365..5020517) Escherichia coli CFT073 1037470 NP_757120.1 CDS yjfM NC_004431.1 5020579 5021094 D Escherichia coli K-12 ortholog: b4185; Escherichia coli O157:H7 ortholog: z5792; hypothetical protein 5020579..5021094 Escherichia coli CFT073 1037469 NP_757121.1 CDS yjfC NC_004431.1 5021339 5022259 D Escherichia coli K-12 ortholog: b4186; Escherichia coli O157:H7 ortholog: z5793; hypothetical protein 5021339..5022259 Escherichia coli CFT073 1037468 NP_757122.1 CDS aidB NC_004431.1 5022325 5023968 D catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 5022325..5023968 Escherichia coli CFT073 1037466 NP_757123.1 CDS yjfN NC_004431.1 5024085 5024387 R Escherichia coli K-12 ortholog: b4188; Escherichia coli O157:H7 ortholog: z5795; hypothetical protein complement(5024085..5024387) Escherichia coli CFT073 1037465 NP_757124.2 CDS yjfO NC_004431.1 5024509 5024838 R in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; biofilm stress and motility protein A complement(5024509..5024838) Escherichia coli CFT073 1037464 NP_757125.1 CDS yjfP NC_004431.1 5025020 5025769 D YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 5025020..5025769 Escherichia coli CFT073 1037463 NP_757126.1 CDS yjfQ NC_004431.1 5025766 5026521 R negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR complement(5025766..5026521) Escherichia coli CFT073 1037462 NP_757127.1 CDS yjfR NC_004431.1 5026629 5027699 R Escherichia coli K-12 ortholog: b4192; Escherichia coli O157:H7 ortholog: z5801; L-ascorbate 6-phosphate lactonase complement(5026629..5027699) Escherichia coli CFT073 1037461 NP_757128.1 CDS ulaA NC_004431.1 5028048 5029445 D membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 5028048..5029445 Escherichia coli CFT073 1037460 NP_757129.1 CDS c5282 NC_004431.1 5029442 5029777 R hypothetical protein complement(5029442..5029777) Escherichia coli CFT073 1037459 NP_757130.1 CDS sgaB NC_004431.1 5029455 5029766 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIB 5029455..5029766 Escherichia coli CFT073 1037458 NP_757131.1 CDS ptxA NC_004431.1 5029776 5030240 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIA 5029776..5030240 Escherichia coli CFT073 1037457 NP_757132.2 CDS ulaD NC_004431.1 5030254 5030904 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 5030254..5030904 Escherichia coli CFT073 1037456 NP_757133.1 CDS c5286 NC_004431.1 5030260 5030928 R hypothetical protein complement(5030260..5030928) Escherichia coli CFT073 1037455 NP_757134.1 CDS sgaU NC_004431.1 5030914 5031768 D UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 5030914..5031768 Escherichia coli CFT073 1037453 NP_757135.2 CDS sgaE NC_004431.1 5031768 5032454 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 5031768..5032454 Escherichia coli CFT073 1037452 NP_757136.1 CDS yjfY NC_004431.1 5032583 5032858 R Escherichia coli K-12 ortholog: b4199; Escherichia coli O157:H7 ortholog: z5808; hypothetical protein complement(5032583..5032858) Escherichia coli CFT073 1037450 NP_757137.1 CDS c5290 NC_004431.1 5033084 5033467 R hypothetical protein complement(5033084..5033467) Escherichia coli CFT073 1037448 NP_757138.1 CDS rpsF NC_004431.1 5033186 5033581 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 5033186..5033581 Escherichia coli CFT073 1037446 NP_757139.1 CDS rpsR NC_004431.1 5033907 5034134 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 5033907..5034134 Escherichia coli CFT073 1037445 NP_757140.1 CDS c5293 NC_004431.1 5034149 5034637 R hypothetical protein complement(5034149..5034637) Escherichia coli CFT073 1037444 NP_757141.1 CDS rplI NC_004431.1 5034176 5034625 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 5034176..5034625 Escherichia coli CFT073 1037443 NP_757142.1 CDS c5295 NC_004431.1 5035027 5035518 D hypothetical protein 5035027..5035518 Escherichia coli CFT073 1037442 NP_757143.1 CDS c5296 NC_004431.1 5035521 5036108 D hypothetical protein 5035521..5036108 Escherichia coli CFT073 1037441 NP_757144.1 CDS c5297 NC_004431.1 5036179 5036790 D Residues 6 to 200 of 203 are 26.49 pct identical to residues 235 to 430 of 435 from GenPept.129 : >gb|AAK24734.1| (AE005942) hypothetical protein [Caulobacter crescentus CB15]; hypothetical protein 5036179..5036790 Escherichia coli CFT073 1037436 NP_757145.1 CDS c5298 NC_004431.1 5036933 5038210 R Escherichia coli K-12 ortholog: b3093; Escherichia coli O157:H7 ortholog: z4446; hexuronate transporter complement(5036933..5038210) Escherichia coli CFT073 1037433 NP_757146.1 CDS c5299 NC_004431.1 5038303 5040375 R Residues 29 to 688 of 690 are 35.69 pct identical to residues 5 to 663 of 664 from GenPept.129 : >gb|AAD35512.1|AE001721_11 (AE001721) oxidoreductase, [Thermotoga maritima]; oxidoreductase complement(5038303..5040375) Escherichia coli CFT073 1037432 NP_757147.1 CDS c5300 NC_004431.1 5040372 5041913 R Residues 3 to 507 of 513 are 46.16 pct identical to residues 4 to 507 of 525 from GenPept.129 : >dbj|BAB07617.1| (AP001520) acetyl-CoA:acetoacetyl-CoA transferase [Bacillus halodurans]; acetyl-CoA:acetoacetyl-CoA transferase complement(5040372..5041913) Escherichia coli CFT073 1037430 NP_757148.1 CDS c5301 NC_004431.1 5041923 5042699 R Residues 4 to 255 of 258 are 36.75 pct identical to residues 3 to 254 of 256 from GenPept.129 : >gb|AAK65427.1| (AE007264) dehydratase [Sinorhizobium meliloti]; hypothetical protein complement(5041923..5042699) Escherichia coli CFT073 1037429 NP_757149.1 CDS c5302 NC_004431.1 5042709 5043551 R Residues 1 to 268 of 280 are 97.76 pct identical to residues 1 to 268 of 294 from GenPept.129 : >gb|AAL50626.1|AF417476_3 (AF417476) unknown [Shigella flexneri]; hypothetical protein complement(5042709..5043551) Escherichia coli CFT073 1037427 NP_757150.1 CDS fabG NC_004431.1 5043561 5044352 R catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(5043561..5044352) Escherichia coli CFT073 1037426 NP_757151.1 CDS c5304 NC_004431.1 5044493 5045212 D Residues 132 to 239 of 239 are 97.22 pct identical to residues 1 to 108 of 108 from MG1655 : b4205; hypothetical protein 5044493..5045212 Escherichia coli CFT073 1037425 NP_757152.1 CDS ytfB NC_004431.1 5045196 5045870 R Escherichia coli K-12 ortholog: b4206; Escherichia coli O157:H7 ortholog: z5817; hypothetical protein complement(5045196..5045870) Escherichia coli CFT073 1037424 NP_757153.2 CDS fklB NC_004431.1 5046052 5046672 D FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 5046052..5046672 Escherichia coli CFT073 1037423 NP_757154.1 CDS cycA NC_004431.1 5046982 5048394 D involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 5046982..5048394 Escherichia coli CFT073 1037421 NP_757155.1 CDS ytfE NC_004431.1 5048439 5049101 R Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein complement(5048439..5049101) Escherichia coli CFT073 1037420 NP_757156.1 CDS ytfF NC_004431.1 5049209 5050183 R Escherichia coli K-12 ortholog: b4210; Escherichia coli O157:H7 ortholog: z5821; hypothetical protein complement(5049209..5050183) Escherichia coli CFT073 1037419 NP_757157.1 CDS ytfG NC_004431.1 5050282 5051142 R Escherichia coli K-12 ortholog: b4211; Escherichia coli O157:H7 ortholog: z5822; hypothetical protein complement(5050282..5051142) Escherichia coli CFT073 1037418 NP_757158.1 CDS ytfH NC_004431.1 5051120 5051611 D Escherichia coli K-12 ortholog: b4212; Escherichia coli O157:H7 ortholog: z5823; hypothetical protein 5051120..5051611 Escherichia coli CFT073 1037417 NP_757159.1 CDS c5312 NC_004431.1 5051740 5051976 R Residues 1 to 78 of 78 are 97.43 pct identical to residues 570 to 647 of 647 from MG1655 : b4213; hypothetical protein complement(5051740..5051976) Escherichia coli CFT073 1037416 NP_757160.1 CDS cysQ NC_004431.1 5053873 5054613 D catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 5053873..5054613 Escherichia coli CFT073 1037415 NP_757161.1 CDS c5314 NC_004431.1 5054603 5055160 R Escherichia coli K-12 ortholog: b4216; Escherichia coli O157:H7 ortholog: z5827; hypothetical protein complement(5054603..5055160) Escherichia coli CFT073 1037414 NP_757162.1 CDS ytfK NC_004431.1 5055419 5055691 D Escherichia coli K-12 ortholog: b4217; Escherichia coli O157:H7 ortholog: z5828; hypothetical protein 5055419..5055691 Escherichia coli CFT073 1037413 NP_757163.1 CDS ytfL NC_004431.1 5055769 5057112 R Escherichia coli K-12 ortholog: b4218; Escherichia coli O157:H7 ortholog: z5829; hypothetical protein complement(5055769..5057112) Escherichia coli CFT073 1037412 NP_757164.1 CDS msrA NC_004431.1 5057435 5058139 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A complement(5057435..5058139) Escherichia coli CFT073 1037410 NP_757165.1 CDS ytfM NC_004431.1 5058279 5060012 D Escherichia coli K-12 ortholog: b4220; Escherichia coli O157:H7 ortholog: z5831; hypothetical protein 5058279..5060012 Escherichia coli CFT073 1037409 NP_757166.1 CDS ytfN NC_004431.1 5060009 5063788 D Escherichia coli K-12 ortholog: b4221; Escherichia coli O157:H7 ortholog: z5832; hypothetical protein 5060009..5063788 Escherichia coli CFT073 1037407 NP_757167.1 CDS ytfP NC_004431.1 5063791 5064132 D Escherichia coli K-12 ortholog: b4222; Escherichia coli O157:H7 ortholog: z5833; hypothetical protein 5063791..5064132 Escherichia coli CFT073 1037404 NP_757168.1 CDS c5321 NC_004431.1 5064282 5065754 D Residues 34 to 117 of 490 are 35.71 pct identical to residues 237 to 320 of 327 from MG1655 : b0644; hypothetical protein 5064282..5065754 Escherichia coli CFT073 1037403 NP_757169.1 CDS c5322 NC_004431.1 5065817 5065957 R hypothetical protein complement(5065817..5065957) Escherichia coli CFT073 1037402 NP_757170.1 CDS ppa NC_004431.1 5066168 5066698 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(5066168..5066698) Escherichia coli CFT073 1037400 NP_757171.1 CDS c5324 NC_004431.1 5066710 5066835 R hypothetical protein complement(5066710..5066835) Escherichia coli CFT073 1037399 NP_757172.1 CDS ytfQ NC_004431.1 5067008 5067964 D Escherichia coli K-12 ortholog: b4227; Escherichia coli O157:H7 ortholog: z5838; ABC transporter periplasmic-binding protein 5067008..5067964 Escherichia coli CFT073 1037398 NP_757173.1 CDS ytfR NC_004431.1 5068104 5069606 D Escherichia coli K-12 ortholog: b4228; Escherichia coli O157:H7 ortholog: z5839; ABC transporter ATP-binding protein 5068104..5069606 Escherichia coli CFT073 1037394 NP_757174.1 CDS ytfT NC_004431.1 5069596 5070642 D Escherichia coli K-12 ortholog: b4230; Escherichia coli O157:H7 ortholog: z5840; ABC transporter permease 5069596..5070642 Escherichia coli CFT073 1037393 NP_757175.1 CDS yjfF NC_004431.1 5070629 5071624 D membrane component of a sugar ABC transporter system; ABC transporter permease 5070629..5071624 Escherichia coli CFT073 1037391 NP_757176.1 CDS fbp NC_004431.1 5071657 5072718 R catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase complement(5071657..5072718) Escherichia coli CFT073 1037390 NP_757177.1 CDS c5330 NC_004431.1 5072718 5072849 D hypothetical protein 5072718..5072849 Escherichia coli CFT073 1037385 NP_757178.1 CDS yjfG NC_004431.1 5072831 5074204 D Escherichia coli K-12 ortholog: b4233; Escherichia coli O157:H7 ortholog: z5843; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelat e ligase 5072831..5074204 Escherichia coli CFT073 1037383 NP_757179.1 CDS yjgA NC_004431.1 5074362 5074913 R X96 protein; Escherichia coli K-12 ortholog: b4234; Escherichia coli O157:H7 ortholog: z5844; hypothetical protein complement(5074362..5074913) Escherichia coli CFT073 1037382 NP_757180.1 CDS pmbA NC_004431.1 5075007 5076359 D protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 5075007..5076359 Escherichia coli CFT073 1037380 NP_757181.1 CDS c5334 NC_004431.1 5076398 5076808 R hypothetical protein complement(5076398..5076808) Escherichia coli CFT073 1037379 NP_757182.1 CDS cybC NC_004431.1 5076543 5076929 D Cytochrome b-562; Escherichia coli K-12 ortholog: b4236; Escherichia coli O157:H7 ortholog: z5846; soluble cytochrome b562 5076543..5076929 Escherichia coli CFT073 1037377 NP_757183.1 CDS nrdG NC_004431.1 5076974 5077438 R activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein complement(5076974..5077438) Escherichia coli CFT073 1037376 NP_757184.1 CDS nrdD NC_004431.1 5077596 5079734 R Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase complement(5077596..5079734) Escherichia coli CFT073 1037373 NP_757185.1 CDS treC NC_004431.1 5080128 5081783 R Escherichia coli K-12 ortholog: b4239; Escherichia coli O157:H7 ortholog: z5849; trehalose-6-phosphate hydrolase complement(5080128..5081783) Escherichia coli CFT073 1037372 NP_757186.1 CDS treB NC_004431.1 5081833 5083254 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunits IIBC complement(5081833..5083254) Escherichia coli CFT073 1037371 NP_757187.1 CDS treR NC_004431.1 5083373 5084320 R regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor complement(5083373..5084320) Escherichia coli CFT073 1037370 NP_757188.1 CDS mgtA NC_004431.1 5084699 5087395 D P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 5084699..5087395 Escherichia coli CFT073 1037368 NP_757189.1 CDS yjgF NC_004431.1 5087601 5088059 R Escherichia coli K-12 ortholog: b4243; Escherichia coli O157:H7 ortholog: z5854; hypothetical protein complement(5087601..5088059) Escherichia coli CFT073 1037367 NP_757190.1 CDS c5343 NC_004431.1 5087694 5088158 D hypothetical protein 5087694..5088158 Escherichia coli CFT073 1037366 NP_757191.1 CDS pyrI NC_004431.1 5088060 5088521 R involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase complement(5088060..5088521) Escherichia coli CFT073 1037365 NP_757192.1 CDS pyrB NC_004431.1 5088534 5089469 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase complement(5088534..5089469) Escherichia coli CFT073 1037364 NP_757193.1 CDS pyrL NC_004431.1 5089473 5089607 R Attenuator; Escherichia coli K-12 ortholog: b4246; pyrBI operon leader peptide complement(5089473..5089607) Escherichia coli CFT073 1037363 NP_757194.1 CDS c5346 NC_004431.1 5089697 5090251 R Residues 23 to 184 of 184 are 87.03 pct identical to residues 1 to 162 of 162 from GenPept.129 : >gb|AAL23282.1| (AE008909) arginine repressor [Salmonella typhimurium LT2]; hypothetical protein complement(5089697..5090251) Escherichia coli CFT073 1037362 NP_757195.1 CDS c5347 NC_004431.1 5090301 5091749 R Residues 16 to 482 of 482 are 89.93 pct identical to residues 1 to 467 of 467 from GenPept.129 : >emb|CAD06924.1| (AL627283) membrane protein [Salmonella enterica subsp. enterica serovar Typhi]; hypothetical protein complement(5090301..5091749) Escherichia coli CFT073 1037361 NP_757196.2 CDS c5348 NC_004431.1 5091761 5092765 R catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase complement(5091761..5092765) Escherichia coli CFT073 1037360 NP_757197.1 CDS c5349 NC_004431.1 5092789 5093721 R reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase complement(5092789..5093721) Escherichia coli CFT073 1037359 NP_757198.1 CDS c5350 NC_004431.1 5093732 5094955 R catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase complement(5093732..5094955) Escherichia coli CFT073 1037358 NP_757199.1 CDS c5351 NC_004431.1 5095040 5095174 R hypothetical protein complement(5095040..5095174) Escherichia coli CFT073 1037357 NP_757200.1 CDS yjgK NC_004431.1 5095630 5096082 D Escherichia coli K-12 ortholog: b4252; Escherichia coli O157:H7 ortholog: z5864; hypothetical protein 5095630..5096082 Escherichia coli CFT073 1037356 NP_757201.1 CDS argI NC_004431.1 5096127 5097131 R catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase; when both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III; ornithine carbamoyltransferase subunit F complement(5096127..5097131) Escherichia coli CFT073 1037355 NP_757202.1 CDS yjgD NC_004431.1 5097293 5097709 D Escherichia coli K-12 ortholog: b4255; Escherichia coli O157:H7 ortholog: z5867; hypothetical protein 5097293..5097709 Escherichia coli CFT073 1037354 NP_757203.1 CDS c5355 NC_004431.1 5097887 5098408 R Residues 7 to 173 of 173 are 91.61 pct identical to residues 1 to 167 of 167 from SwissProt.40 : >sp|P39337|YJGM_ECOLI HYPOTHETICAL 18.6 KDA PROTEIN IN ARGI-VALS INTERGENIC REGION; hypothetical protein complement(5097887..5098408) Escherichia coli CFT073 1037353 NP_757204.1 CDS c5356 NC_004431.1 5098583 5099113 D Residues 1 to 144 of 176 are 64.58 pct identical to residues 1 to 144 of 395 from GenPept.129 : >gb|AAL23293.1| (AE008910) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein 5098583..5099113 Escherichia coli CFT073 1037351 NP_757205.1 CDS c5357 NC_004431.1 5099082 5099771 D Residues 4 to 229 of 229 are 37.44 pct identical to residues 167 to 393 of 393 from MG1655 : b4257; hypothetical protein 5099082..5099771 Escherichia coli CFT073 1037347 NP_757206.1 CDS valS NC_004431.1 5099818 5102673 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(5099818..5102673) Escherichia coli CFT073 1037346 NP_757207.1 CDS holC NC_004431.1 5102673 5103116 R binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi complement(5102673..5103116) Escherichia coli CFT073 1037337 NP_757208.1 CDS pepA NC_004431.1 5103374 5104885 R catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase complement(5103374..5104885) Escherichia coli CFT073 1037328 NP_757209.1 CDS c5361 NC_004431.1 5105110 5105238 R hypothetical protein complement(5105110..5105238) Escherichia coli CFT073 1037324 NP_757210.1 CDS yjgP NC_004431.1 5105152 5106252 D Escherichia coli K-12 ortholog: b4261; Escherichia coli O157:H7 ortholog: z5873; hypothetical protein 5105152..5106252 Escherichia coli CFT073 1037320 NP_757211.1 CDS yjgQ NC_004431.1 5106249 5107334 D Escherichia coli K-12 ortholog: b4262; Escherichia coli O157:H7 ortholog: z5874; hypothetical protein 5106249..5107334 Escherichia coli CFT073 1037318 NP_757212.1 CDS yjgR NC_004431.1 5107495 5108997 R Escherichia coli K-12 ortholog: b4263; Escherichia coli O157:H7 ortholog: z5875; hypothetical protein complement(5107495..5108997) Escherichia coli CFT073 1037316 NP_757213.1 CDS idnR NC_004431.1 5109075 5110103 R Escherichia coli K-12 ortholog: b4264; Escherichia coli O157:H7 ortholog: z4806; L-idonate regulatory protein complement(5109075..5110103) Escherichia coli CFT073 1037310 NP_757214.1 CDS idnT NC_004431.1 5110140 5111459 R L-Ido transporter; Escherichia coli K-12 ortholog: b4265; Escherichia coli O157:H7 ortholog: z4770; Gnt-II system L-idonate transporter complement(5110140..5111459) Escherichia coli CFT073 1037303 NP_757215.1 CDS idnO NC_004431.1 5111524 5112288 R Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase complement(5111524..5112288) Escherichia coli CFT073 1037302 NP_757216.1 CDS idnD NC_004431.1 5112312 5113343 R NAD-binding; L-idonate 5-dehydrogenase complement(5112312..5113343) Escherichia coli CFT073 1037299 NP_757217.1 CDS idnK NC_004431.1 5113560 5114123 D Escherichia coli K-12 ortholog: b4268; Escherichia coli O157:H7 ortholog: z4805; D-gluconate kinase 5113560..5114123 Escherichia coli CFT073 1037293 NP_757218.1 CDS yjgB NC_004431.1 5114127 5115188 R Escherichia coli K-12 ortholog: b4269; Escherichia coli O157:H7 ortholog: z5876; hypothetical protein complement(5114127..5115188) Escherichia coli CFT073 1037290 NP_757219.1 CDS c5371 NC_004431.1 5115549 5116700 D Int(P4); Escherichia coli K-12 ortholog: b4271; Escherichia coli O157:H7 ortholog: z5890; prophage P4 integrase 5115549..5116700 Escherichia coli CFT073 1037279 NP_757220.1 CDS c5372 NC_004431.1 5116943 5120014 R Residues 1 to 1022 of 1023 are 51.23 pct identical to residues 1 to 1041 of 1043 from GenPept.129 : >gb|AAK02783.1| (AE006106) unknown [Pasteurella multocida]; hypothetical protein complement(5116943..5120014) Escherichia coli CFT073 1037278 NP_757221.1 CDS c5373 NC_004431.1 5120028 5122040 R Residues 2 to 668 of 670 are 43.91 pct identical to residues 3 to 634 of 636 from GenPept.129 : >gb|AAK02782.1| (AE006106) unknown [Pasteurella multocida]; hypothetical protein complement(5120028..5122040) Escherichia coli CFT073 1037276 NP_757222.1 CDS c5374 NC_004431.1 5122071 5122415 D hypothetical protein 5122071..5122415 Escherichia coli CFT073 1037275 NP_757223.1 CDS c5375 NC_004431.1 5122185 5122343 R hypothetical protein complement(5122185..5122343) Escherichia coli CFT073 1037273 NP_757224.1 CDS c5376 NC_004431.1 5122193 5122630 R hypothetical protein complement(5122193..5122630) Escherichia coli CFT073 1037272 NP_757225.1 CDS c5377 NC_004431.1 5122627 5123328 R Residues 11 to 227 of 233 are 37.94 pct identical to residues 1 to 220 of 220 from GenPept.129 : >gb|AAK02781.1| (AE006106) unknown [Pasteurella multocida]; hypothetical protein complement(5122627..5123328) Escherichia coli CFT073 1037271 NP_757226.1 CDS c5378 NC_004431.1 5123325 5126603 R Residues 1 to 1090 of 1092 are 60.92 pct identical to residues 1 to 1088 of 1089 from GenPept.129 : >gb|AAK02780.1| (AE006106) unknown [Pasteurella multocida]; hypothetical protein complement(5123325..5126603) Escherichia coli CFT073 1037270 NP_757227.1 CDS c5379 NC_004431.1 5126603 5127508 R Residues 9 to 293 of 301 are 47.90 pct identical to residues 20 to 305 of 308 from GenPept.129 : >gb|AAM08019.1| (AY090559) hypothetical protein [Providencia rettgeri]; hypothetical protein complement(5126603..5127508) Escherichia coli CFT073 1037269 NP_757228.1 CDS c5380 NC_004431.1 5126849 5127133 D hypothetical protein 5126849..5127133 Escherichia coli CFT073 1037268 NP_757229.1 CDS c5381 NC_004431.1 5127677 5127964 R Residues 14 to 75 of 95 are 82.25 pct identical to residues 1 to 62 of 200 from GenPept.129 : >gb|AAL23316.1| (AE008911) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein complement(5127677..5127964) Escherichia coli CFT073 1037267 NP_757230.1 CDS c5382 NC_004431.1 5128222 5128935 D Residues 87 to 229 of 237 are 81.81 pct identical to residues 1 to 143 of 245 from GenPept.129 : >gb|AAL23321.1| (AE008912) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein 5128222..5128935 Escherichia coli CFT073 1037264 NP_757231.1 CDS c5383 NC_004431.1 5128919 5129590 R Residues 46 to 199 of 223 are 30.57 pct identical to residues 20 to 172 of 188 from GenPept.129 : >dbj|BAB06239.1| (AP001515) transposase related protein (20) [Bacillus halodurans]; hypothetical protein complement(5128919..5129590) Escherichia coli CFT073 1037262 NP_757232.1 CDS c5384 NC_004431.1 5129587 5129979 R hypothetical protein complement(5129587..5129979) Escherichia coli CFT073 1037260 NP_757233.1 CDS c5385 NC_004431.1 5130249 5130578 D Residues 6 to 106 of 109 are 70.29 pct identical to residues 143 to 243 of 245 from GenPept.129 : >gb|AAL23321.1| (AE008912) inner membrane protein [Salmonella typhimurium LT2]; hypothetical protein 5130249..5130578 Escherichia coli CFT073 1037259 NP_757234.1 CDS c5386 NC_004431.1 5131079 5131210 D hypothetical protein 5131079..5131210 Escherichia coli CFT073 1037257 NP_757235.1 CDS c5387 NC_004431.1 5131337 5132317 R Escherichia coli K-12 ortholog: b4309; Escherichia coli O157:H7 ortholog: z5905; hypothetical protein complement(5131337..5132317) Escherichia coli CFT073 1037256 NP_757236.1 CDS c5388 NC_004431.1 5132382 5133596 R Escherichia coli K-12 ortholog: b4310; Escherichia coli O157:H7 ortholog: z5906; N-acetylneuraminic acid mutarotase complement(5132382..5133596) Escherichia coli CFT073 1037254 NP_757237.1 CDS c5389 NC_004431.1 5133508 5134233 R Escherichia coli K-12 ortholog: b4311; Escherichia coli O157:H7 ortholog: z5907; hypothetical protein complement(5133508..5134233) Escherichia coli CFT073 1037252 NP_757238.1 CDS c5390 NC_004431.1 5135022 5135429 R hypothetical protein complement(5135022..5135429) Escherichia coli CFT073 1037251 NP_757239.1 CDS fimB NC_004431.1 5135689 5136291 D inversion of on/off regulator of fimA; tyrosine recombinase 5135689..5136291 Escherichia coli CFT073 1037250 NP_757240.1 CDS fimE NC_004431.1 5136769 5137365 D inversion of on/off regulator of fimA; tyrosine recombinase 5136769..5137365 Escherichia coli CFT073 1037249 NP_757241.1 CDS fimA NC_004431.1 5137789 5138394 D Type-1A pilin; Escherichia coli K-12 ortholog: b4314; Escherichia coli O157:H7 ortholog: z5912; Type-1 fimbrial protein, A chain 5137789..5138394 Escherichia coli CFT073 1037247 NP_757242.1 CDS fimI NC_004431.1 5138459 5138998 D Escherichia coli K-12 ortholog: b4315; Escherichia coli O157:H7 ortholog: z5913; fimbrin-like protein fimI 5138459..5138998 Escherichia coli CFT073 1037245 NP_757243.1 CDS fimC NC_004431.1 5139035 5139760 D Escherichia coli K-12 ortholog: b4316; Escherichia coli O157:H7 ortholog: z5914; chaperone protein fimC 5139035..5139760 Escherichia coli CFT073 1037243 NP_757244.1 CDS fimD NC_004431.1 5139826 5142462 D Escherichia coli K-12 ortholog: b4317; Escherichia coli O157:H7 ortholog: z5915; outer membrane usher protein fimD 5139826..5142462 Escherichia coli CFT073 1037242 NP_757245.1 CDS fimF NC_004431.1 5142469 5143002 D Escherichia coli K-12 ortholog: b4318; Escherichia coli O157:H7 ortholog: z5916; FimF protein 5142469..5143002 Escherichia coli CFT073 1037237 NP_757246.1 CDS c5398 NC_004431.1 5142996 5143124 R hypothetical protein complement(5142996..5143124) Escherichia coli CFT073 1037236 NP_757247.1 CDS fimG NC_004431.1 5143015 5143518 D Escherichia coli K-12 ortholog: b4319; Escherichia coli O157:H7 ortholog: z5917; FimG protein 5143015..5143518 Escherichia coli CFT073 1037235 NP_757248.1 CDS fimH NC_004431.1 5143529 5144440 D Escherichia coli K-12 ortholog: b4320; Escherichia coli O157:H7 ortholog: z5918; FimH protein 5143529..5144440 Escherichia coli CFT073 1037233 NP_757249.1 CDS gntP NC_004431.1 5144682 5146025 R Gluconate permease 3; Escherichia coli K-12 ortholog: b4321; Escherichia coli O157:H7 ortholog: z5919; fructuronate transporter complement(5144682..5146025) Escherichia coli CFT073 1037232 NP_757250.1 CDS uxuA NC_004431.1 5146365 5147549 D catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 5146365..5147549 Escherichia coli CFT073 1037231 NP_757251.1 CDS uxuB NC_004431.1 5147630 5149090 D Escherichia coli K-12 ortholog: b4323; Escherichia coli O157:H7 ortholog: z5921; D-mannonate oxidoreductase 5147630..5149090 Escherichia coli CFT073 1037227 NP_757252.1 CDS uxuR NC_004431.1 5149305 5150078 D regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR 5149305..5150078 Escherichia coli CFT073 1037226 NP_757253.1 CDS iraD NC_004431.1 5150483 5150875 D inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS; DNA replication/recombination/repair protein 5150483..5150875 Escherichia coli CFT073 1037225 NP_757254.1 CDS c5406 NC_004431.1 5150923 5151264 R Residues 1 to 113 of 113 are 95.57 pct identical to residues 424 to 536 of 536 from GenPept.129 : >gb|AAL61895.1| (AF289032) phosphoenolpyruvate-protein phosphoryltransferase PptE [Escherichia coli]; hypothetical protein complement(5150923..5151264) Escherichia coli CFT073 1037223 NP_757255.1 CDS yjiE NC_004431.1 5151301 5152290 R Escherichia coli K-12 ortholog: b4327; Escherichia coli O157:H7 ortholog: z5926; DNA-binding transcriptional regulator complement(5151301..5152290) Escherichia coli CFT073 1037222 NP_757256.1 CDS iadA NC_004431.1 5152277 5153449 R Escherichia coli K-12 ortholog: b4328; Escherichia coli O157:H7 ortholog: z5927; isoaspartyl dipeptidase complement(5152277..5153449) Escherichia coli CFT073 1037220 NP_757257.1 CDS yjiG NC_004431.1 5153462 5153923 R Escherichia coli K-12 ortholog: b4329; Escherichia coli O157:H7 ortholog: z5928; hypothetical protein complement(5153462..5153923) Escherichia coli CFT073 1037212 NP_757258.1 CDS yjiH NC_004431.1 5153920 5154615 R Escherichia coli K-12 ortholog: b4330; Escherichia coli O157:H7 ortholog: z5929; hypothetical protein complement(5153920..5154615) Escherichia coli CFT073 1037209 NP_757259.1 CDS c5411 NC_004431.1 5154615 5154746 D hypothetical protein 5154615..5154746 Escherichia coli CFT073 1037208 NP_757260.1 CDS yjiJ NC_004431.1 5155419 5156597 R Escherichia coli K-12 ortholog: b4332; Escherichia coli O157:H7 ortholog: z5933; hypothetical protein complement(5155419..5156597) Escherichia coli CFT073 1037190 NP_757261.1 CDS yjiK NC_004431.1 5156665 5157636 R Escherichia coli K-12 ortholog: b4333; Escherichia coli O157:H7 ortholog: z5934; hypothetical protein complement(5156665..5157636) Escherichia coli CFT073 1037188 NP_757262.1 CDS c5416 NC_004431.1 5157590 5157847 R Residues 1 to 80 of 85 are 87.50 pct identical to residues 1 to 80 of 88 from GenPept.129 : >dbj|BAB38719.1| (AP002569) hypothetical protein [Escherichia coli O157:H7]; hypothetical protein complement(5157590..5157847) Escherichia coli CFT073 1037185 NP_757263.1 CDS yjiL NC_004431.1 5157844 5158617 R Escherichia coli K-12 ortholog: b4334; Escherichia coli O157:H7 ortholog: z5936; hypothetical protein complement(5157844..5158617) Escherichia coli CFT073 1037182 NP_757264.1 CDS yjiM NC_004431.1 5158621 5159793 R Escherichia coli K-12 ortholog: b4335; Escherichia coli O157:H7 ortholog: z5937; hypothetical protein complement(5158621..5159793) Escherichia coli CFT073 1037177 NP_757265.1 CDS yjiN NC_004431.1 5159888 5161204 R Escherichia coli K-12 ortholog: b4336; Escherichia coli O157:H7 ortholog: z5938; hypothetical protein complement(5159888..5161204) Escherichia coli CFT073 1037169 NP_757266.1 CDS yfcI NC_004431.1 5161353 5162273 D Escherichia coli K-12 ortholog: b2305; Escherichia coli O157:H7 ortholog: z5940; hypothetical protein 5161353..5162273 Escherichia coli CFT073 1037166 NP_757267.1 CDS c5421 NC_004431.1 5162553 5164772 D Residues 43 to 734 of 739 are 65.23 pct identical to residues 1 to 697 of 702 from GenPept.129 : >gb|AAM05803.1| (AE010933) conserved hypothetical protein [Methanosarcina acetivorans str. C2A]; hypothetical protein 5162553..5164772 Escherichia coli CFT073 1037158 NP_757268.1 CDS yjiW NC_004431.1 5164819 5165160 R involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE complement(5164819..5165160) Escherichia coli CFT073 1037156 NP_757269.1 CDS c5423 NC_004431.1 5165381 5167150 R Escherichia coli O157:H7 ortholog: z5946; restriction modification enzyme S subunit complement(5165381..5167150) Escherichia coli CFT073 1037148 NP_757270.1 CDS c5424 NC_004431.1 5167150 5168673 R Methylase; Escherichia coli O157:H7 ortholog: z5947; restriction modification enzyme M subunit complement(5167150..5168673) Escherichia coli CFT073 1037142 NP_757271.1 CDS c5425 NC_004431.1 5168686 5171118 R Endonuclease; Escherichia coli O157:H7 ortholog: z5948; restriction modification enzyme R subunit complement(5168686..5171118) Escherichia coli CFT073 1037140 NP_757272.1 CDS c5426 NC_004431.1 5171375 5173048 D Escherichia coli O157:H7 ortholog: z5950; hypothetical protein 5171375..5173048 Escherichia coli CFT073 1037138 NP_757273.1 CDS yjiA NC_004431.1 5173117 5174112 R Escherichia coli K-12 ortholog: b4352; Escherichia coli O157:H7 ortholog: z5951; GTP-binding protein YjiA complement(5173117..5174112) Escherichia coli CFT073 1037135 NP_757274.1 CDS c5428 NC_004431.1 5174084 5174287 R Escherichia coli K-12 ortholog: b4353; Escherichia coli O157:H7 ortholog: z5952; hypothetical protein complement(5174084..5174287) Escherichia coli CFT073 1037133 NP_757275.1 CDS yjiY NC_004431.1 5174405 5176570 R Escherichia coli K-12 ortholog: b4354; Escherichia coli O157:H7 ortholog: z5953; hypothetical protein complement(5174405..5176570) Escherichia coli CFT073 1037130 NP_757276.1 CDS tsr NC_004431.1 5176932 5178596 D MCP-I; Escherichia coli K-12 ortholog: b4355; Escherichia coli O157:H7 ortholog: z5955; methyl-accepting chemotaxis protein I 5176932..5178596 Escherichia coli CFT073 1037129 NP_757277.1 CDS c5431 NC_004431.1 5178639 5179910 R Residues 1 to 422 of 423 are 42.31 pct identical to residues 1 to 423 of 428 from GenPept.129 : >gb|AAL95452.1| (AE010631) C4-dicarboxylate transporter large subunit [Fusobacterium nucleatum subsp. nucleatum ATCC 25586]; hypothetical protein complement(5178639..5179910) Escherichia coli CFT073 1037125 NP_757278.1 CDS c5432 NC_004431.1 5179907 5180380 R Residues 19 to 144 of 157 are 29.92 pct identical to residues 7 to 133 of 174 from GenPept.129 : >emb|CAC26718.1| (AX066981) RXN02955 [Corynebacterium glutamicum]; hypothetical protein complement(5179907..5180380) Escherichia coli CFT073 1037122 NP_757279.1 CDS c5433 NC_004431.1 5180444 5181253 R Residues 4 to 268 of 269 are 32.33 pct identical to residues 58 to 323 of 325 from GenPept.129 : >emb|CAC49506.1| (AL603646) C4-dicarboxylate transporter periplasmic solute-binding protein precursor [Sinorhizobium meliloti]; C4-dicarboxylate-binding periplasmic protein complement(5180444..5181253) Escherichia coli CFT073 1037121 NP_757280.1 CDS c5434 NC_004431.1 5181253 5181417 R hypothetical protein complement(5181253..5181417) Escherichia coli CFT073 1037120 NP_757281.1 CDS c5435 NC_004431.1 5182087 5183760 D Escherichia coli K-12 ortholog: b4065; Escherichia coli O157:H7 ortholog: z5664; Na(+)/H(+) exchanger yjcE 5182087..5183760 Escherichia coli CFT073 1037119 NP_757282.1 CDS yjjM NC_004431.1 5183931 5184836 R Escherichia coli K-12 ortholog: b4357; Escherichia coli O157:H7 ortholog: z5957; hypothetical protein complement(5183931..5184836) Escherichia coli CFT073 1037118 NP_757283.1 CDS c5437 NC_004431.1 5184975 5185997 D Escherichia coli K-12 ortholog: b4358; Escherichia coli O157:H7 ortholog: z5958; hypothetical protein 5184975..5185997 Escherichia coli CFT073 1037115 NP_757284.1 CDS mdoB NC_004431.1 5186137 5188428 R catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I complement(5186137..5188428) Escherichia coli CFT073 1037114 NP_757285.1 CDS yjjA NC_004431.1 5188682 5189179 R Protein P-18; Escherichia coli K-12 ortholog: b4360; Escherichia coli O157:H7 ortholog: z5960; hypothetical protein complement(5188682..5189179) Escherichia coli CFT073 1037113 NP_757286.1 CDS dnaC NC_004431.1 5189225 5189962 R acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC complement(5189225..5189962) Escherichia coli CFT073 1037112 NP_757287.1 CDS dnaT NC_004431.1 5189965 5190504 R This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI complement(5189965..5190504) Escherichia coli CFT073 1037111 NP_757288.2 CDS yjjB NC_004431.1 5190612 5191085 R Protein P-14; Escherichia coli K-12 ortholog: b4363; Escherichia coli O157:H7 ortholog: z5963; hypothetical protein complement(5190612..5191085) Escherichia coli CFT073 1037110 NP_757289.1 CDS yjjP NC_004431.1 5191076 5191909 R Escherichia coli K-12 ortholog: b4364; Escherichia coli O157:H7 ortholog: z5964; hypothetical protein complement(5191076..5191909) Escherichia coli CFT073 1037107 NP_757290.1 CDS yjjQ NC_004431.1 5192466 5193191 D Escherichia coli K-12 ortholog: b4365; Escherichia coli O157:H7 ortholog: z5966; hypothetical protein 5192466..5193191 Escherichia coli CFT073 1037106 NP_757291.2 CDS bglJ NC_004431.1 5193203 5193826 D regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 5193203..5193826 Escherichia coli CFT073 1037105 NP_757292.1 CDS fhuF NC_004431.1 5193864 5194652 R Escherichia coli K-12 ortholog: b4367; Escherichia coli O157:H7 ortholog: z5968; ferric iron reductase involved in ferric hydroximate transport complement(5193864..5194652) Escherichia coli CFT073 1037103 NP_757293.1 CDS c5447 NC_004431.1 5194682 5195029 D Residues 38 to 115 of 115 are 96.15 pct identical to residues 1 to 78 of 78 from SwissProt.40 : >sp|P55914|YJJZ_ECOLI Hypothetical protein yjjZ; hypothetical protein 5194682..5195029 Escherichia coli CFT073 1037102 NP_757294.1 CDS c5448 NC_004431.1 5194885 5195040 D hypothetical protein 5194885..5195040 Escherichia coli CFT073 1037101 NP_757295.1 CDS c5449 NC_004431.1 5195456 5195578 R hypothetical protein complement(5195456..5195578) Escherichia coli CFT073 1037093 NP_757296.1 CDS rsmC NC_004431.1 5195590 5196621 R 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase complement(5195590..5196621) Escherichia coli CFT073 1037091 YP_004853838.1 CDS c5451 NC_004431.1 5196612 5197001 D hypothetical protein 5196612..5197001 Escherichia coli CFT073 1037090 NP_757298.1 CDS holD NC_004431.1 5196724 5197137 D with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 5196724..5197137 Escherichia coli CFT073 1037089 NP_757299.1 CDS rimI NC_004431.1 5197106 5197552 D alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 5197106..5197552 Escherichia coli CFT073 1037088 NP_757300.1 CDS yjjG NC_004431.1 5197567 5198244 D manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 5197567..5198244 Escherichia coli CFT073 1037087 NP_757301.1 CDS c5455 NC_004431.1 5198259 5198411 D hypothetical protein 5198259..5198411 Escherichia coli CFT073 1037081 NP_757302.1 CDS prfC NC_004431.1 5198335 5199924 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 5198335..5199924 Escherichia coli CFT073 1037078 NP_757303.1 CDS osmY NC_004431.1 5200239 5200922 D Escherichia coli K-12 ortholog: b4376; Escherichia coli O157:H7 ortholog: z5977; periplasmic protein 5200239..5200922 Escherichia coli CFT073 1037077 NP_757304.1 CDS c5458 NC_004431.1 5200284 5200976 R hypothetical protein complement(5200284..5200976) Escherichia coli CFT073 1037076 NP_757305.1 CDS c5459 NC_004431.1 5201019 5201210 D Escherichia coli O157:H7 ortholog: z5978; hypothetical protein 5201019..5201210 Escherichia coli CFT073 1037071 NP_757306.1 CDS yjjU NC_004431.1 5201296 5202405 D Escherichia coli K-12 ortholog: b4377; Escherichia coli O157:H7 ortholog: z5979; hypothetical protein 5201296..5202405 Escherichia coli CFT073 1037068 NP_757307.1 CDS yjjV NC_004431.1 5202402 5203181 D Escherichia coli K-12 ortholog: b4378; Escherichia coli O157:H7 ortholog: z5980; deoxyribonuclease YjjV 5202402..5203181 Escherichia coli CFT073 1037067 NP_757308.1 CDS yjjW NC_004431.1 5203398 5204261 R Escherichia coli K-12 ortholog: b4379; Escherichia coli O157:H7 ortholog: z5981; hypothetical protein complement(5203398..5204261) Escherichia coli CFT073 1037066 NP_757309.1 CDS yjjI NC_004431.1 5204233 5205783 R Escherichia coli K-12 ortholog: b4380; Escherichia coli O157:H7 ortholog: z5982; hypothetical protein complement(5204233..5205783) Escherichia coli CFT073 1037065 NP_757310.1 CDS c5464 NC_004431.1 5205759 5205884 D hypothetical protein 5205759..5205884 Escherichia coli CFT073 1037062 NP_757311.1 CDS deoC NC_004431.1 5206017 5206820 D catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 5206017..5206820 Escherichia coli CFT073 1037031 NP_757312.2 CDS deoA NC_004431.1 5206898 5208220 D Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 5206898..5208220 Escherichia coli CFT073 1037030 NP_757313.1 CDS deoB NC_004431.1 5208272 5209495 D catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 5208272..5209495 Escherichia coli CFT073 1037025 NP_757314.2 CDS deoD NC_004431.1 5209552 5210271 D catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 5209552..5210271 Escherichia coli CFT073 1037020 NP_757315.1 CDS c5469 NC_004431.1 5210429 5210938 D Residues 18 to 169 of 169 are 94.07 pct identical to residues 1 to 152 of 152 from SwissProt.40 : >sp|Q57334|T200_SALTY Transposase for insertion sequence element IS200; transposase 5210429..5210938 Escherichia coli CFT073 1037006 NP_757316.1 CDS yjjJ NC_004431.1 5211150 5212481 D Escherichia coli K-12 ortholog: b4385; hypothetical protein 5211150..5212481 Escherichia coli CFT073 1036990 NP_757317.1 CDS lplA NC_004431.1 5212482 5213498 R Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A complement(5212482..5213498) Escherichia coli CFT073 1036989 NP_757318.1 CDS smp NC_004431.1 5213526 5214170 R Escherichia coli K-12 ortholog: b4387; hypothetical protein complement(5213526..5214170) Escherichia coli CFT073 1036987 NP_757319.2 CDS serB NC_004431.1 5214276 5215244 D catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 5214276..5215244 Escherichia coli CFT073 1036985 NP_757320.1 CDS sms NC_004431.1 5215245 5216675 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 5215245..5216675 Escherichia coli CFT073 1036984 NP_757321.2 CDS nadR NC_004431.1 5216696 5217928 D catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 5216696..5217928 Escherichia coli CFT073 1036976 NP_757322.1 CDS c5476 NC_004431.1 5217942 5218352 D Residues 32 to 135 of 136 are 36.19 pct identical to residues 4 to 108 of 110 from GenPept.129 : >gb|AAF96372.1| (AE004379) hypothetical protein [Vibrio cholerae]; hypothetical protein 5217942..5218352 Escherichia coli CFT073 1036965 NP_757323.1 CDS c5477 NC_004431.1 5218354 5218638 D Residues 16 to 85 of 94 are 38.57 pct identical to residues 6 to 75 of 84 from GenPept.129 : >gb|AAL22872.1| (AE008888) bacterial regulatory protein, merR family [Salmonella typhimurium LT2]; hypothetical protein 5218354..5218638 Escherichia coli CFT073 1036944 NP_757324.1 CDS yjjK NC_004431.1 5218694 5220361 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein complement(5218694..5220361) Escherichia coli CFT073 1036942 NP_757325.1 CDS slt NC_004431.1 5220568 5222505 D catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 5220568..5222505 Escherichia coli CFT073 1036935 NP_757326.1 CDS trpR NC_004431.1 5222595 5222921 D When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 5222595..5222921 Escherichia coli CFT073 1036896 NP_757327.2 CDS yjjX NC_004431.1 5222994 5223521 R pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase complement(5222994..5223521) Escherichia coli CFT073 1036892 NP_757328.1 CDS gpmB NC_004431.1 5223573 5224220 D catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 5223573..5224220 Escherichia coli CFT073 1036888 NP_757329.1 CDS rob NC_004431.1 5224217 5225086 R Escherichia coli K-12 ortholog: b4396; Escherichia coli O157:H7 ortholog: z5999; right origin-binding protein complement(5224217..5225086) Escherichia coli CFT073 1036880 NP_757330.1 CDS creA NC_004431.1 5225297 5225770 D Escherichia coli K-12 ortholog: b4397; Escherichia coli O157:H7 ortholog: z6000; hypothetical protein 5225297..5225770 Escherichia coli CFT073 1036870 NP_757331.1 CDS creB NC_004431.1 5225783 5226472 D response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 5225783..5226472 Escherichia coli CFT073 1036841 NP_757332.1 CDS creC NC_004431.1 5226472 5227896 D part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 5226472..5227896 Escherichia coli CFT073 1036835 NP_757333.1 CDS creD NC_004431.1 5227954 5229306 D Escherichia coli K-12 ortholog: b4400; Escherichia coli O157:H7 ortholog: z6003; hypothetical protein 5227954..5229306 Escherichia coli CFT073 1036814 NP_757334.1 CDS arcA NC_004431.1 5229366 5230082 R Dye resistance protein; Escherichia coli K-12 ortholog: b4401; Escherichia coli O157:H7 ortholog: z6004; two-component response regulator complement(5229366..5230082) Escherichia coli CFT073 1036809 NP_757335.1 CDS yjjY NC_004431.1 5230178 5230318 D Escherichia coli K-12 ortholog: b4402; Escherichia coli O157:H7 ortholog: z6005; hypothetical protein 5230178..5230318 Escherichia coli CFT073 1036801 NP_757336.2 CDS lasT NC_004431.1 5230718 5231404 D member of the SPOUT superfamily of methyltransferases; RNA methyltransferase 5230718..5231404 Escherichia coli CFT073 1036781 c5511 tRNA c5511 NC_004431.1 236813 236889 D tRNA-Glu 236813..236889 Escherichia coli CFT073 1035866 c5512 tRNA c5512 NC_004431.1 236902 236976 D tRNA-Ala 236902..236976 Escherichia coli CFT073 1035587 c5513 tRNA aspU NC_004431.1 240329 240405 D tRNA-Asp 240329..240405 Escherichia coli CFT073 1037001 c5514 tRNA aspV NC_004431.1 248554 248630 D tRNA-Asp 248554..248630 Escherichia coli CFT073 1036561 c5515 tRNA thrW NC_004431.1 370224 370299 D tRNA-Thr 370224..370299 Escherichia coli CFT073 1036308 c5516 tRNA c5516 NC_004431.1 434982 435062 D tRNA-OTHER 434982..435062 Escherichia coli CFT073 1036245 c5517 tRNA c5517 NC_004431.1 627071 627147 D tRNA-Arg 627071..627147 Escherichia coli CFT073 1039532 c5518 tRNA glnX NC_004431.1 729302 729376 R tRNA-Gln complement(729302..729376) Escherichia coli CFT073 1038254 c5519 tRNA glnV NC_004431.1 729414 729488 R tRNA-Gln complement(729414..729488) Escherichia coli CFT073 1038267 c5520 tRNA metU NC_004431.1 729537 729613 R tRNA-Met complement(729537..729613) Escherichia coli CFT073 1039837 c5521 tRNA glnW NC_004431.1 729629 729703 R tRNA-Gln complement(729629..729703) Escherichia coli CFT073 1039667 c5522 tRNA glnU NC_004431.1 729738 729812 R tRNA-Gln complement(729738..729812) Escherichia coli CFT073 1039867 c5523 tRNA c5523 NC_004431.1 729836 729920 R tRNA-Leu complement(729836..729920) Escherichia coli CFT073 1039895 c5524 tRNA c5524 NC_004431.1 729931 730007 R tRNA-Met complement(729931..730007) Escherichia coli CFT073 1040118 c5525 tRNA lysT NC_004431.1 803225 803300 D tRNA-Lys 803225..803300 Escherichia coli CFT073 1038663 c5526 tRNA valT NC_004431.1 803336 803411 D tRNA-Val 803336..803411 Escherichia coli CFT073 1038474 c5527 tRNA lysW NC_004431.1 803414 803489 D tRNA-Lys 803414..803489 Escherichia coli CFT073 1038498 c5528 tRNA valZ NC_004431.1 803541 803616 D tRNA-Val 803541..803616 Escherichia coli CFT073 1038576 c5529 tRNA lysY NC_004431.1 803620 803695 D tRNA-Lys 803620..803695 Escherichia coli CFT073 1038706 c5530 tRNA lysZ NC_004431.1 803744 803819 D tRNA-Lys 803744..803819 Escherichia coli CFT073 1035832 c5531 tRNA lysQ NC_004431.1 803853 803928 D tRNA-Lys 803853..803928 Escherichia coli CFT073 1038371 c5532 tRNA serW NC_004431.1 980013 980100 R tRNA-Ser complement(980013..980100) Escherichia coli CFT073 1038547 c5533 tRNA serT NC_004431.1 1075414 1075501 R tRNA-Ser complement(1075414..1075501) Escherichia coli CFT073 1039026 c5534 tRNA c5534 NC_004431.1 1211152 1211228 D tRNA-Arg 1211152..1211228 Escherichia coli CFT073 1034941 c5535 tRNA serX NC_004431.1 1241062 1241149 R tRNA-Ser complement(1241062..1241149) Escherichia coli CFT073 1034988 c5536 tRNA c5536 NC_004431.1 1342304 1342379 D tRNA-Met 1342304..1342379 Escherichia coli CFT073 1035138 c5537 tRNA c5537 NC_004431.1 1342387 1342463 D tRNA-Arg 1342387..1342463 Escherichia coli CFT073 1035139 c5538 tRNA c5538 NC_004431.1 1342477 1342553 D tRNA-Arg 1342477..1342553 Escherichia coli CFT073 1035140 c5539 tRNA tyrV NC_004431.1 1532391 1532475 R tRNA-Tyr complement(1532391..1532475) Escherichia coli CFT073 1035476 c5540 tRNA tyrT NC_004431.1 1532509 1532593 R tRNA-Tyr complement(1532509..1532593) Escherichia coli CFT073 1035477 c5541 tRNA valV NC_004431.1 1902573 1902649 D tRNA-Val 1902573..1902649 Escherichia coli CFT073 1036208 c5542 tRNA valW NC_004431.1 1902654 1902730 D tRNA-Val 1902654..1902730 Escherichia coli CFT073 1036216 c5543 tRNA leuZ NC_004431.1 2140492 2140578 R tRNA-Leu complement(2140492..2140578) Escherichia coli CFT073 1036941 c5544 tRNA cysT NC_004431.1 2140591 2140664 R tRNA-Cys complement(2140591..2140664) Escherichia coli CFT073 1036946 c5545 tRNA glyW NC_004431.1 2140718 2140793 R tRNA-Gly complement(2140718..2140793) Escherichia coli CFT073 1036948 c5546 tRNA serU NC_004431.1 2216841 2216930 R tRNA-Ser complement(2216841..2216930) Escherichia coli CFT073 1037323 c5547 tRNA asnT NC_004431.1 2217922 2217997 D tRNA-Asn 2217922..2217997 Escherichia coli CFT073 1037326 c5548 tRNA asnV NC_004431.1 2258516 2258591 R tRNA-Asn complement(2258516..2258591) Escherichia coli CFT073 1037583 c5549 tRNA asnU NC_004431.1 2260925 2261000 R tRNA-Asn complement(2260925..2261000) Escherichia coli CFT073 1037593 c5550 tRNA asnW NC_004431.1 2262749 2262824 D tRNA-Asn 2262749..2262824 Escherichia coli CFT073 1037630 c5551 tRNA proL NC_004431.1 2576748 2576824 D tRNA-Pro 2576748..2576824 Escherichia coli CFT073 1038131 c5552 tRNA argW NC_004431.1 2746725 2746799 D tRNA-Arg 2746725..2746799 Escherichia coli CFT073 1038463 c5553 tRNA alaX NC_004431.1 2799076 2799151 R tRNA-Ala complement(2799076..2799151) Escherichia coli CFT073 1038536 c5554 tRNA alaW NC_004431.1 2799191 2799266 R tRNA-Ala complement(2799191..2799266) Escherichia coli CFT073 1038538 c5555 tRNA valU NC_004431.1 2801965 2802040 D tRNA-Val 2801965..2802040 Escherichia coli CFT073 1038543 c5556 tRNA valX NC_004431.1 2802084 2802159 D tRNA-Val 2802084..2802159 Escherichia coli CFT073 1038548 c5557 tRNA valY NC_004431.1 2802206 2802281 D tRNA-Val 2802206..2802281 Escherichia coli CFT073 1038550 c5558 tRNA lysV NC_004431.1 2802286 2802361 D tRNA-Lys 2802286..2802361 Escherichia coli CFT073 1038556 c5559 tRNA gltW NC_004431.1 2992062 2992137 R tRNA-Glu complement(2992062..2992137) Escherichia coli CFT073 1038833 c5560 tRNA c5560 NC_004431.1 3100380 3100456 R tRNA-Arg complement(3100380..3100456) Escherichia coli CFT073 1039021 c5561 tRNA argQ NC_004431.1 3100520 3100596 R tRNA-Arg complement(3100520..3100596) Escherichia coli CFT073 1039022 c5562 tRNA argZ NC_004431.1 3100659 3100735 R tRNA-Arg complement(3100659..3100735) Escherichia coli CFT073 1039023 c5563 tRNA argY NC_004431.1 3100798 3100874 R tRNA-Arg complement(3100798..3100874) Escherichia coli CFT073 1039025 c5564 tRNA argV NC_004431.1 3100939 3101015 R tRNA-Arg complement(3100939..3101015) Escherichia coli CFT073 1039029 c5565 tRNA serV NC_004431.1 3101019 3101111 R tRNA-Ser complement(3101019..3101111) Escherichia coli CFT073 1039030 c5566 tRNA metZ NC_004431.1 3222091 3222167 D tRNA-Met 3222091..3222167 Escherichia coli CFT073 1039238 c5567 tRNA metW NC_004431.1 3222201 3222277 D tRNA-Met 3222201..3222277 Escherichia coli CFT073 1039239 c5568 tRNA metV NC_004431.1 3222311 3222387 D tRNA-Met 3222311..3222387 Escherichia coli CFT073 1039241 c5569 tRNA glyU NC_004431.1 3295426 3295499 R tRNA-Gly complement(3295426..3295499) Escherichia coli CFT073 1039321 c5570 tRNA pheV NC_004431.1 3406225 3406300 D tRNA-Phe 3406225..3406300 Escherichia coli CFT073 1039476 c5571 tRNA ileX NC_004431.1 3656193 3656268 D tRNA-Ile 3656193..3656268 Escherichia coli CFT073 1039977 c5572 tRNA metY NC_004431.1 3751846 3751922 R tRNA-Met complement(3751846..3751922) Escherichia coli CFT073 1040267 c5573 tRNA leuU NC_004431.1 3755703 3755789 R tRNA-Leu complement(3755703..3755789) Escherichia coli CFT073 1040272 c5574 tRNA c5574 NC_004431.1 3858429 3858504 R tRNA-Glu complement(3858429..3858504) Escherichia coli CFT073 1040470 c5575 tRNA proK NC_004431.1 4147653 4147729 R tRNA-Pro complement(4147653..4147729) Escherichia coli CFT073 1037344 c5576 tRNA selC NC_004431.1 4274308 4274398 D tRNA-Sec 4274308..4274398 Escherichia coli CFT073 1038454 c5577 tRNA gltU NC_004431.1 4444468 4444543 D tRNA-Glu 4444468..4444543 Escherichia coli CFT073 1040418 c5578 tRNA aspT NC_004431.1 4447909 4447985 D tRNA-Asp 4447909..4447985 Escherichia coli CFT073 1040450 c5579 tRNA trpT NC_004431.1 4447994 4448069 D tRNA-Trp 4447994..4448069 Escherichia coli CFT073 1036469 c5580 tRNA argX NC_004431.1 4482539 4482615 D tRNA-Arg 4482539..4482615 Escherichia coli CFT073 1036496 c5581 tRNA hisR NC_004431.1 4482673 4482749 D tRNA-His 4482673..4482749 Escherichia coli CFT073 1036241 c5582 tRNA leuT NC_004431.1 4482770 4482856 D tRNA-Leu 4482770..4482856 Escherichia coli CFT073 1036504 c5583 tRNA proM NC_004431.1 4482899 4482975 D tRNA-Pro 4482899..4482975 Escherichia coli CFT073 1036329 c5584 tRNA ileT NC_004431.1 4562805 4562881 D tRNA-Ile 4562805..4562881 Escherichia coli CFT073 1035777 c5585 tRNA alaT NC_004431.1 4562924 4562999 D tRNA-Ala 4562924..4562999 Escherichia coli CFT073 1036515 c5586 tRNA gltT NC_004431.1 4700785 4700860 D tRNA-Glu 4700785..4700860 Escherichia coli CFT073 1039899 c5587 tRNA thrU NC_004431.1 4707636 4707711 D tRNA-Thr 4707636..4707711 Escherichia coli CFT073 1039889 c5588 tRNA tyrU NC_004431.1 4707720 4707804 D tRNA-Tyr 4707720..4707804 Escherichia coli CFT073 1039887 c5589 tRNA glyT NC_004431.1 4707921 4707995 D tRNA-Gly 4707921..4707995 Escherichia coli CFT073 1039886 c5590 tRNA thrT NC_004431.1 4708002 4708077 D tRNA-Thr 4708002..4708077 Escherichia coli CFT073 1039883 c5591 tRNA gltV NC_004431.1 4740956 4741031 D tRNA-Glu 4740956..4741031 Escherichia coli CFT073 1039838 c5592 tRNA pheU NC_004431.1 4971585 4971660 R tRNA-Phe complement(4971585..4971660) Escherichia coli CFT073 1037535 c5593 tRNA glyV NC_004431.1 5000526 5000601 D tRNA-Gly 5000526..5000601 Escherichia coli CFT073 1037499 c5594 tRNA glyX NC_004431.1 5000638 5000713 D tRNA-Gly 5000638..5000713 Escherichia coli CFT073 1037498 c5595 tRNA glyY NC_004431.1 5000749 5000824 D tRNA-Gly 5000749..5000824 Escherichia coli CFT073 1037497 c5596 tRNA leuX NC_004431.1 5115342 5115426 D tRNA-Leu 5115342..5115426 Escherichia coli CFT073 1037283 c5597 tRNA leuV NC_004431.1 5195068 5195154 R tRNA-Leu complement(5195068..5195154) Escherichia coli CFT073 1037098 c5598 tRNA leuP NC_004431.1 5195189 5195275 R tRNA-Leu complement(5195189..5195275) Escherichia coli CFT073 1037096 c5599 tRNA leuQ NC_004431.1 5195304 5195390 R tRNA-Leu complement(5195304..5195390) Escherichia coli CFT073 1037094 c5600 rRNA rrsH NC_004431.1 235186 236727 D 16S ribosomal RNA 235186..236727 Escherichia coli CFT073 1036596 c5601 rRNA rrlH NC_004431.1 237160 240063 D 23S ribosomal RNA 237160..240063 Escherichia coli CFT073 1040377 c5602 rRNA rrfH NC_004431.1 240157 240276 D 5S ribosomal RNA 240157..240276 Escherichia coli CFT073 1036070 c5615 rRNA rrfG NC_004431.1 2988760 2988879 R 5S ribosomal RNA complement(2988760..2988879) Escherichia coli CFT073 1038830 c5616 rRNA rrlG NC_004431.1 2988973 2991877 R 23S ribosomal RNA complement(2988973..2991877) Escherichia coli CFT073 1038832 c5617 rRNA rrsG NC_004431.1 2992309 2993859 R 16S ribosomal RNA complement(2992309..2993859) Escherichia coli CFT073 1038836 c5618 rRNA rrfD NC_004431.1 3855028 3855140 R 5S ribosomal RNA complement(3855028..3855140) Escherichia coli CFT073 1040460 c5619 rRNA rrlD NC_004431.1 3855236 3858140 R 23S ribosomal RNA complement(3855236..3858140) Escherichia coli CFT073 1040463 c5620 rRNA rrsD NC_004431.1 3858590 3860131 R 16S ribosomal RNA complement(3858590..3860131) Escherichia coli CFT073 1040476 c5603 rRNA rrsC NC_004431.1 4442840 4444382 D 16S ribosomal RNA 4442840..4444382 Escherichia coli CFT073 1040467 c5604 rRNA rrlC NC_004431.1 4444737 4447644 D 23S ribosomal RNA 4444737..4447644 Escherichia coli CFT073 1040475 c5605 rRNA rrfC NC_004431.1 4447738 4447857 D 5S ribosomal RNA 4447738..4447857 Escherichia coli CFT073 1040480 c5606 rRNA rrsA NC_004431.1 4561194 4562736 D 16S ribosomal RNA 4561194..4562736 Escherichia coli CFT073 1036521 c5607 rRNA rrlA NC_004431.1 4563174 4566081 D 23S ribosomal RNA 4563174..4566081 Escherichia coli CFT073 1036233 c5608 rRNA rrfA NC_004431.1 4566175 4566294 D 5S ribosomal RNA 4566175..4566294 Escherichia coli CFT073 1038449 c5609 rRNA rrsB NC_004431.1 4699063 4700613 D 16S ribosomal RNA 4699063..4700613 Escherichia coli CFT073 1040020 c5610 rRNA rrlB NC_004431.1 4701054 4703957 D 23S ribosomal RNA 4701054..4703957 Escherichia coli CFT073 1039897 c5611 rRNA rrfB NC_004431.1 4704051 4704170 D 5S ribosomal RNA 4704051..4704170 Escherichia coli CFT073 1039894 c5612 rRNA rrsE NC_004431.1 4739329 4740870 D 16S ribosomal RNA 4739329..4740870 Escherichia coli CFT073 1039839 c5613 rRNA rrlE NC_004431.1 4741226 4744132 D 23S ribosomal RNA 4741226..4744132 Escherichia coli CFT073 1039836 c5614 rRNA rrfE NC_004431.1 4744226 4744345 D 5S ribosomal RNA 4744226..4744345 Escherichia coli CFT073 1039834