-- dump date 20140619_081956 -- class Genbank::CDS -- table cds_note -- id note YP_001451374.1 identified by glimmer; putative YP_001451375.1 identified by similarity to GB:CAC92481.1 YP_001451376.1 identified by glimmer; putative YP_001451377.1 identified by match to protein family HMM PF00872 YP_001451378.1 identified by match to protein family HMM PF02371 YP_001451379.1 identified by glimmer; putative YP_001451380.1 identified by similarity to SP:P11904; match to protein family HMM PF06406 YP_001451381.1 identified by glimmer; putative YP_001451382.1 identified by match to protein family HMM PF01381 YP_001451383.1 identified by match to protein family HMM PF05973 YP_001451386.1 This gene is disrupted by the insertion of a group II intron.; identified by match to protein family HMM PF00665 YP_001451387.1 identified by match to protein family HMM PF00078; match to protein family HMM PF08388 YP_001451389.1 identified by similarity to GB:ABB64661.1 YP_001451390.1 identified by similarity to SP:P43530; match to protein family HMM PF01375 YP_001451391.1 identified by match to protein family HMM PF00665 YP_001451392.1 identified by match to protein family HMM PF00665 YP_001451393.1 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180 YP_001451394.1 identified by match to protein family HMM PF06290 YP_001451395.1 PsiA YP_001451396.1 identified by similarity to GB:CAC86755.1 YP_001451397.1 identified by glimmer; putative YP_001451398.1 identified by similarity to SP:P14565 YP_001451399.1 identified by similarity to SP:P22710; match to protein family HMM PF05857; match to protein family HMM TIGR02755 YP_001451400.1 identified by match to protein family HMM PF00561 YP_001451401.2 identified by similarity to SP:P29367; match to protein family HMM PF05286 YP_001451402.1 identified by glimmer; putative YP_001451403.1 identified by glimmer; putative YP_001451404.1 identified by glimmer; putative YP_001451405.1 identified by similarity to GB:AAM90728.1 YP_001451406.1 RepA YP_001451407.1 identified by match to protein family HMM PF05973 YP_001451408.1 identified by match to protein family HMM PF01381 YP_001451409.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001451410.1 identified by glimmer; putative YP_001451412.1 identified by match to protein family HMM PF04393 YP_001451413.1 identified by match to protein family HMM PF00534 YP_001451414.1 identified by match to protein family HMM PF01522 YP_001451415.1 identified by similarity to GB:AAZ89280.1 YP_001451416.1 identified by similarity to GB:AAZ89279.1 YP_001451417.1 identified by similarity to SP:P62552; match to protein family HMM PF07362 YP_001451418.1 controlled cell death protein; post-segregation toxin; toxin addiction system YP_001451419.1 identified by similarity to SP:P06615; match to protein family HMM PF00589 YP_001451420.1 identified by similarity to SP:P07175 YP_001451421.1 identified by similarity to GB:AAK48856.1 YP_001451423.1 identified by match to protein family HMM PF00308; match to protein family HMM PF01695 YP_001451424.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001451425.1 identified by similarity to GB:AAP16553.1 YP_001451426.1 identified by match to protein family HMM PF03811 YP_001451427.1 identified by match to protein family HMM PF03400 YP_001451428.1 identified by similarity to SP:P16114; match to protein family HMM PF00165 YP_001451429.1 identified by similarity to GB:AAP16553.1 YP_001451430.1 identified by match to protein family HMM PF02687 YP_001451431.1 identified by glimmer; putative YP_001451432.1 identified by glimmer; putative YP_001451433.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats YP_001451434.1 identified by similarity to SP:P51026; match to protein family HMM PF00665 YP_001451436.1 identified by match to protein family HMM PF01527 YP_001451438.1 identified by match to protein family HMM PF01527 YP_001451439.1 identified by similarity to GB:AAP16553.1 YP_001451440.1 identified by match to protein family HMM PF00665 YP_001451441.1 identified by match to protein family HMM PF08479 YP_001451442.1 identified by similarity to SP:P22708; match to protein family HMM TIGR02759 YP_001451443.1 identified by similarity to SP:P13980; match to protein family HMM PF05818 YP_001451444.1 identified by similarity to SP:P33790; match to protein family HMM PF07916 YP_001451445.1 identified by similarity to SP:P15069; match to protein family HMM PF06122 YP_001451446.1 identified by similarity to GB:AAN52975.1 YP_001451447.1 identified by glimmer; putative YP_001451449.1 identified by similarity to GB:AAS76405.1 YP_001451450.1 identified by match to protein family HMM PF03230 YP_001451451.1 identified by similarity to GB:BAB91623.1 YP_001451452.1 identified by similarity to GB:AAR05672.1; match to protein family HMM PF07128 YP_001451453.1 identified by similarity to GB:CAG27544.1 YP_001451454.1 identified by match to protein family HMM PF01555 YP_001451455.1 identified by similarity to GB:AAS76411.1 YP_001451456.1 identified by similarity to GB:AAS76414.1; match to protein family HMM PF06924 YP_001451457.1 identified by similarity to GB:AAS76411.1 YP_001451458.1 identified by similarity to SP:P11906 YP_001451459.1 identified by similarity to SP:P11904; match to protein family HMM PF06406 YP_001451460.1 identified by similarity to GB:CAD76448.1 YP_001451461.1 identified by glimmer; putative YP_001451462.1 identified by match to protein family HMM PF05016 YP_001451463.1 identified by match to protein family HMM PF01402 YP_001451464.1 identified by glimmer; putative YP_001451465.1 identified by glimmer; putative YP_001451466.1 RepA YP_001451467.1 identified by similarity to SP:P13970; match to protein family HMM PF01848 YP_001451468.1 identified by similarity to GB:BAB78149.1 YP_001451469.1 identified by similarity to SP:P22710; match to protein family HMM PF05857; match to protein family HMM TIGR02755 YP_001451470.1 identified by similarity to GB:AAM90728.1 YP_001451471.1 identified by similarity to GB:AAR05684.1; match to protein family HMM PF06006 YP_001451472.1 identified by similarity to SP:P28043; match to protein family HMM PF00436; match to protein family HMM TIGR00621 YP_001451473.1 identified by similarity to GB:AAS76404.1 YP_001451474.1 identified by similarity to GB:AAR05676.1 YP_001451475.1 identified by match to protein family HMM PF03230 YP_001451476.1 identified by similarity to GB:AAS76407.1 YP_001451477.1 identified by similarity to GB:CAG27545.1; match to protein family HMM PF07128 YP_001451478.1 identified by similarity to GB:AAS76409.1 YP_001451479.1 identified by match to protein family HMM PF01555 YP_001451480.1 identified by similarity to GB:AAS76411.1 YP_001451481.1 identified by similarity to GB:AAL72290.1; match to protein family HMM PF06924 YP_001451483.1 identified by similarity to SP:P11904; match to protein family HMM PF06406 YP_001451484.1 identified by similarity to SP:P06615; match to protein family HMM PF00589 YP_001451485.1 identified by similarity to GB:AAA24254.1 YP_001451486.1 identified by glimmer; putative YP_001451487.1 identified by match to protein family HMM PF01850 YP_001451488.1 identified by similarity to GB:AAM37285.1 YP_001451489.1 identified by match to protein family HMM PF03050 YP_001451490.1 identified by match to protein family HMM PF05717 YP_001451491.1 identified by match to protein family HMM PF01527 YP_001451492.1 identified by similarity to GB:AAZ89279.1 YP_001451493.1 identified by similarity to GB:AAZ89280.1 YP_001451494.1 identified by similarity to GB:AAA23190.1 YP_001451495.1 identified by glimmer; putative YP_001451496.1 identified by match to protein family HMM PF00165 YP_001451497.1 identified by match to protein family HMM PF01609 YP_001451498.1 identified by glimmer; putative YP_001451499.1 identified by match to protein family HMM PF00165 YP_001451500.1 identified by match to protein family HMM PF08388 YP_001451501.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats YP_001451502.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats YP_001451503.1 identified by match to protein family HMM PF07434 YP_001451504.1 identified by similarity to GB:AAK97136.1 YP_001451505.1 identified by glimmer; putative YP_001451506.1 identified by glimmer; putative YP_001451507.1 identified by glimmer; putative YP_001451508.1 identified by match to protein family HMM PF00308; match to protein family HMM PF01695 YP_001451509.1 identified by similarity to SP:P15025; match to protein family HMM PF00665 YP_001451512.1 identified by glimmer; putative YP_001451513.1 identified by similarity to SP:P18023 YP_001451514.1 identified by match to protein family HMM PF02357 YP_001451516.1 identified by similarity to GB:AAL05516.1 YP_001451517.1 identified by match to protein family HMM PF07419 YP_001451518.1 identified by match to protein family HMM PF01527 YP_001451519.1 identified by match to protein family HMM PF00078; match to protein family HMM PF08388 YP_001451521.1 identified by match to protein family HMM PF03432 YP_001451525.1 identified by match to protein family HMM PF03050 YP_001451526.1 identified by match to protein family HMM PF05717 YP_001451527.1 identified by match to protein family HMM PF01527 YP_001451530.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_001451534.1 identified by glimmer; putative YP_001451535.1 identified by match to protein family HMM PF07275 YP_001451536.1 identified by similarity to GB:BAB91633.1 YP_001451537.1 PsiA YP_001451538.1 identified by match to protein family HMM PF06290 YP_001451539.1 identified by glimmer; putative YP_001451541.1 identified by match to protein family HMM PF04655 YP_001451542.1 identified by similarity to SP:P18150; match to protein family HMM PF01636 YP_001451543.1 sulfonamide resistance mechanism; identified by match to protein family HMM PF00809; match to protein family HMM TIGR01496 YP_001451544.1 identified by match to protein family HMM PF04986 YP_001451545.1 identified by similarity to GB:CAD31269.1 YP_001451546.1 identified by match to protein family HMM PF01527 YP_001451547.1 identified by match to protein family HMM PF05717 YP_001451548.1 identified by match to protein family HMM PF03050 YP_001451549.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats YP_001451552.1 identified by similarity to GB:AAX22066.1 YP_001451553.1 identified by match to protein family HMM PF04986 YP_001451554.1 identified by similarity to GB:AAR05685.1 YP_001451555.1 identified by similarity to SP:P10032; match to protein family HMM PF06290 YP_001451556.1 PsiA YP_001451557.1 identified by match to protein family HMM PF01527 YP_001451558.1 identified by match to protein family HMM PF00078; match to protein family HMM PF08388 YP_001451559.1 identified by match to protein family HMM PF00308; match to protein family HMM PF01695 YP_001451560.1 identified by similarity to SP:P15025; match to protein family HMM PF00665 YP_001451561.1 identified by similarity to GB:AAR05668.1; match to protein family HMM PF06924 YP_001451562.1 SopB YP_001451563.1 identified by similarity to SP:P62556; match to protein family HMM PF00376; match to protein family HMM PF01656 YP_001451564.1 identified by glimmer; putative YP_001451565.1 identified by match to protein family HMM PF00078; match to protein family HMM PF08388 YP_001451566.1 identified by match to protein family HMM PF01527 YP_001451567.1 identified by match to protein family HMM PF01555 YP_001451568.1 identified by glimmer; putative YP_001451569.1 identified by glimmer; putative YP_001451570.1 identified by glimmer; putative YP_001451571.1 identified by glimmer; putative YP_001451572.1 identified by glimmer; putative YP_001451573.1 identified by similarity to GB:CAI07494.1; match to protein family HMM PF06067 YP_001451574.1 identified by match to protein family HMM PF00308; match to protein family HMM PF01695 YP_001451575.1 identified by similarity to SP:P15025; match to protein family HMM PF00665 YP_001451577.1 identified by match to protein family HMM PF03050 YP_001451578.1 identified by match to protein family HMM PF05717 YP_001451579.1 identified by match to protein family HMM PF01527 YP_001451580.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats YP_001451581.1 identified by similarity to SP:P51026; match to protein family HMM PF00665 YP_001451582.1 identified by match to protein family HMM PF03811 YP_001451583.1 identified by match to protein family HMM PF03400 YP_001451584.1 identified by match to protein family HMM PF01527 YP_001451585.1 identified by match to protein family HMM PF05717 YP_001451586.1 identified by match to protein family HMM PF03050 YP_001451587.1 identified by match to protein family HMM PF03811 YP_001451588.1 identified by similarity to SP:Q84GK0; match to protein family HMM PF02395; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414 YP_001451589.1 identified by similarity to SP:P76135; match to protein family HMM PF00165 YP_001451590.1 identified by match to protein family HMM PF00563 YP_001451591.1 identified by match to protein family HMM PF00239 YP_001451592.1 identified by similarity to SP:P06615; match to protein family HMM PF00589 YP_001451593.1 controlled cell death protein; post-segregation toxin; toxin addiction system YP_001451594.2 identified by similarity to SP:P62552; match to protein family HMM PF07362 YP_001451595.1 identified by similarity to GB:AAZ89279.1 YP_001451596.1 identified by similarity to GB:AAZ89280.1 YP_001451597.1 identified by match to protein family HMM PF01522 YP_001451598.1 identified by match to protein family HMM PF00534 YP_001451599.1 identified by match to protein family HMM PF04393 YP_001451600.1 identified by glimmer; putative YP_001451603.1 identified by match to protein family HMM PF03050 YP_001451604.1 identified by match to protein family HMM PF05717 YP_001451605.1 identified by match to protein family HMM PF01527 YP_001451606.1 identified by glimmer; putative YP_001451607.1 identified by glimmer; putative YP_001451608.1 identified by similarity to SP:P12060; match to protein family HMM PF05513; match to protein family HMM TIGR02758 YP_001451609.1 identified by similarity to SP:P12058; match to protein family HMM PF07178; match to protein family HMM TIGR02762 YP_001451610.1 identified by similarity to SP:P12057; match to protein family HMM PF05309; match to protein family HMM TIGR02761 YP_001451611.1 identified by match to protein family HMM PF07057; match to protein family HMM TIGR02759 YP_001451612.1 identified by match to protein family HMM TIGR02755 YP_001451613.1 identified by glimmer; putative YP_001451614.1 identified by glimmer; putative YP_001451615.1 identified by match to protein family HMM PF03432 YP_001461170.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001461171.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_001461172.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001461173.1 identified by glimmer YP_001461174.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001461175.1 identified by similarity to SP:Q8ZS17; match to protein family HMM PF03883 YP_001461176.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_001461177.1 identified by match to protein family HMM PF00923; match to protein family HMM TIGR00874 YP_001461178.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_001461179.1 identified by match to protein family HMM PF01184 YP_001461180.1 identified by match to protein family HMM PF03667 YP_001461182.1 identified by glimmer YP_001461183.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001461184.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001461185.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_001461186.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_001461187.1 identified by similarity to GB:AAZ86820.1 YP_001461188.1 identified by glimmer YP_001461189.1 identified by glimmer YP_001461190.1 identified by glimmer YP_001461191.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001461192.1 identified by similarity to GB:AAZ86826.1 YP_001461193.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_001461194.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme YP_001461195.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001461196.1 identified by match to protein family HMM PF00254 YP_001461197.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001461198.1 catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides YP_001461199.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001461201.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001461202.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001461203.1 identified by glimmer YP_001461204.1 regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons YP_001461205.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities YP_001461206.2 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA YP_001461207.1 identified by match to protein family HMM PF00501 YP_001461208.1 catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine YP_001461209.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA YP_001461210.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism YP_001461211.1 identified by glimmer YP_001461212.1 identified by similarity to GB:AAX63975.1 YP_001461213.1 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase YP_001461214.1 involved in electron transfer during carnitine metabolism YP_001461215.1 FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction YP_001461217.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_001461218.1 Required for full activity of KefC, a potassium-proton antiporter YP_001461219.1 transport system that facilitates potassium-efflux YP_001461220.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate YP_001461221.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_001461222.1 protein associated with Co2+ and Mg2+ efflux YP_001461223.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001461224.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001461225.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB YP_001461226.1 determines N-hexane tolerance and is involved in outer membrane permeability YP_001461227.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_001461228.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs YP_001461229.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_001461230.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_001461231.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_001461232.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism YP_001461233.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate YP_001461234.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose YP_001461235.1 identified by similarity to SP:P30149; match to protein family HMM PF09335 YP_001461236.1 with TbpA and ThiP is part of the thiamine and TPP transport system YP_001461237.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine YP_001461238.1 part of the thiamine and TPP transport system tbpA-thiPQ YP_001461240.1 activates sgrS under glucose-phosphate stress conditions YP_001461241.1 identified by similarity to SP:P31675; match to protein family HMM PF07690; match to protein family HMM TIGR00899 YP_001461242.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001461243.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001461244.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001461245.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001461246.1 activator for leuABCD operon; member of LysR family of transcriptional activators YP_001461247.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive YP_001461248.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001461249.1 identified by glimmer YP_001461250.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism YP_001461251.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001461252.1 identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006 YP_001461253.1 membrane bound cell division protein at septum containing leucine zipper motif YP_001461254.1 identified by similarity to SP:P0AD68; match to protein family HMM PF00905; match to protein family HMM PF03717 YP_001461255.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001461256.1 identified by similarity to SP:P11880; match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01143 YP_001461257.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001461258.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001461259.1 integral membrane protein involved in stabilizing FstZ ring during cell division YP_001461260.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001461261.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001461262.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001461263.1 involved in septum formation YP_001461264.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane YP_001461265.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001461266.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001461267.1 secM translational pause allows for the initiation of secA translation YP_001461268.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001461269.1 identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586 YP_001461270.1 identified by similarity to GB:AAZ86903.1 YP_001461271.1 identified by similarity to SP:P0A8H8; match to protein family HMM PF03884 YP_001461272.1 identified by match to protein family HMM PF07072 YP_001461273.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_001461274.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate YP_001461275.1 identified by match to protein family HMM PF00437 YP_001461276.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532 YP_001461277.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_001461278.1 identified by similarity to SP:P13016; match to protein family HMM PF01510 YP_001461279.1 involved in regulation of beta-lactamase; signaling protein YP_001461280.1 identified by similarity to SP:P15993; match to protein family HMM PF00324 YP_001461281.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_001461282.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_001461283.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains YP_001461284.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001461285.1 identified by similarity to GB:BAB33544.1 YP_001461286.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001461287.1 identified by similarity to SP:P59396; match to protein family HMM PF06062 YP_001461288.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_001461289.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_001461291.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification YP_001461292.1 identified by similarity to SP:P15877; match to protein family HMM PF01011; match to protein family HMM TIGR03074 YP_001461293.1 identified by similarity to SP:P0A9M2; match to protein family HMM PF00156; match to protein family HMM TIGR01203 YP_001461294.1 catalyzes the interconversion of bicarbonate and carbon dioxide YP_001461295.1 identified by match to protein family HMM PF00005 YP_001461296.1 identified by match to protein family HMM PF01061 YP_001461297.1 identified by match to protein family HMM PF03610 YP_001461298.1 identified by match to protein family HMM PF01522 YP_001461299.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_001461300.1 identified by glimmer YP_001461301.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_001461302.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001461303.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001461304.1 identified by match to protein family HMM PF00419 YP_001461305.1 identified by similarity to GB:AAZ86939.1 YP_001461306.1 identified by match to protein family HMM PF00419 YP_001461307.1 identified by glimmer YP_001461308.1 similar to the fimbrial usher protein PapC YP_001461309.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001461310.1 identified by glimmer YP_001461311.1 identified by similarity to SP:P08190; match to protein family HMM PF00419 YP_001461312.1 catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP YP_001461313.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's YP_001461314.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu YP_001461315.1 identified by match to protein family HMM PF01258; match to protein family HMM TIGR02420 YP_001461316.1 Regulatory factor involved in maltose metabolism YP_001461317.1 identified by match to protein family HMM PF02834; match to protein family HMM TIGR02258 YP_001461318.1 similar in sequence to the ATP-dependent RNA helicase HrpA YP_001461319.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell YP_001461320.1 identified by glimmer YP_001461321.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein YP_001461322.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter YP_001461323.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores YP_001461324.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_001461325.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001461326.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation YP_001461327.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_001461328.1 identified by match to protein family HMM PF03458 YP_001461329.1 solute binding component of the vitamin B12 transport system BtuCDF YP_001461330.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_001461331.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate YP_001461332.1 protease Do; required at high temperature; degrades damaged proteins YP_001461333.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization YP_001461335.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_001461336.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_001461337.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_001461338.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001461339.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001461340.1 Catalyzes the phosphorylation of UMP to UDP YP_001461341.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001461342.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001461343.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_001461344.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate YP_001461345.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response YP_001461346.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins YP_001461347.1 identified by similarity to SP:P31519; match to protein family HMM PF03938 YP_001461348.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001461349.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001461350.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001461351.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001461352.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001461353.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001461354.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_001461355.1 identified by similarity to SP:P52095; match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_001461356.1 identified by match to protein family HMM PF00903 YP_001461357.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase YP_001461358.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination YP_001461359.1 identified by match to protein family HMM PF06786 YP_001461360.1 identified by match to protein family HMM PF07152 YP_001461361.1 identified by match to protein family HMM PF00472 YP_001461362.1 identified by match to protein family HMM PF04170 YP_001461363.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001461364.1 identified by glimmer YP_001461365.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001461366.1 identified by match to protein family HMM PF01980; match to protein family HMM TIGR00104 YP_001461368.1 identified by match to protein family HMM PF03180; match to protein family HMM TIGR00363 YP_001461369.1 part of the MetNIQ methionine uptake system YP_001461370.1 part of the metNIQ transport system for methionine YP_001461371.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_001461372.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid YP_001461373.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001461374.1 identified by match to protein family HMM PF03372 YP_001461375.1 identified by match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_001461376.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall YP_001461377.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione YP_001461378.1 identified by match to protein family HMM PF08241 YP_001461379.1 identified by glimmer YP_001461380.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_001461381.1 3'-5' exonuclease of DNA polymerase III YP_001461382.1 identified by glimmer YP_001461385.1 identified by similarity to GB:CAE12300.1; match to protein family HMM PF05638; match to protein family HMM TIGR03344 YP_001461386.1 identified by match to protein family HMM PF06812 YP_001461387.1 identified by match to protein family HMM PF06744; match to protein family HMM PF06761; match to protein family HMM TIGR03348 YP_001461388.1 identified by match to protein family HMM PF06812; match to protein family HMM TIGR03362 YP_001461389.1 identified by match to protein family HMM TIGR03360 YP_001461390.1 identified by match to protein family HMM PF00004; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03345 YP_001461391.1 identified by similarity to GB:AAF96029.1; match to protein family HMM TIGR03349 YP_001461392.1 identified by similarity to GB:AAM83869.1; match to protein family HMM PF05936; match to protein family HMM TIGR03353 YP_001461393.1 identified by match to protein family HMM TIGR03352 YP_001461394.1 identified by similarity to GB:CAC92824.1; match to protein family HMM TIGR03354 YP_001461395.1 identified by similarity to GB:BAB33651.1; match to protein family HMM PF06996; match to protein family HMM TIGR03347 YP_001461396.1 identified by similarity to GB:AAZ87034.1; match to protein family HMM PF05947; match to protein family HMM TIGR03359 YP_001461397.1 identified by similarity to GB:CAG76342.1; match to protein family HMM PF04965; match to protein family HMM TIGR03357 YP_001461398.1 identified by similarity to GB:BAB33654.1; match to protein family HMM PF05943; match to protein family HMM TIGR03355 YP_001461399.1 identified by glimmer YP_001461400.1 identified by similarity to GB:AAZ87038.1; match to protein family HMM PF05591; match to protein family HMM TIGR03358 YP_001461401.1 identified by glimmer YP_001461402.1 identified by match to protein family HMM PF05638; match to protein family HMM TIGR03344 YP_001461403.1 identified by glimmer YP_001461404.1 identified by match to protein family HMM PF04524; match to protein family HMM PF06715; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361 YP_001461405.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643 YP_001461407.1 identified by match to protein family HMM PF00795 YP_001461408.1 inactivates vertebrate C-type lysozyme YP_001461409.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001461410.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_001461411.1 identified by glimmer YP_001461412.1 identified by match to protein family HMM PF00310 YP_001461413.1 identified by match to protein family HMM PF06104 YP_001461414.1 identified by match to protein family HMM PF05016; match to protein family HMM TIGR00053; match to protein family HMM TIGR02385 YP_001461415.1 identified by similarity to SP:Q47150; match to protein family HMM PF04221; match to protein family HMM TIGR02384 YP_001461416.1 identified by match to protein family HMM PF00877 YP_001461417.1 identified by glimmer YP_001461418.1 identified by match to protein family HMM PF05534 YP_001461419.1 identified by match to protein family HMM PF00771 YP_001461420.1 identified by match to protein family HMM PF00691 YP_001461421.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001461422.1 identified by match to protein family HMM PF00583 YP_001461423.1 mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY YP_001461424.1 similar to release factor 1 and 2 YP_001461425.1 identified by similarity to SP:P15288; match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01893 YP_001461426.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_001461427.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation YP_001461428.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS YP_001461429.1 identified by similarity to SP:P02932; match to protein family HMM PF00267; match to protein family HMM TIGR03304 YP_001461430.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001461431.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001461432.1 identified by glimmer YP_001461433.1 identified by match to protein family HMM PF05930 YP_001461434.1 identified by glimmer YP_001461435.1 identified by glimmer YP_001461436.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271 YP_001461437.1 identified by glimmer YP_001461438.1 identified by glimmer YP_001461439.1 identified by glimmer YP_001461440.1 identified by match to protein family HMM PF02384 YP_001461441.1 identified by match to protein family HMM PF01420 YP_001461442.1 identified by similarity to GB:CAF28525.1 YP_001461443.1 identified by similarity to GB:AAB70710.1; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM TIGR00348 YP_001461444.1 identified by similarity to SP:P15038; match to protein family HMM PF00580; match to protein family HMM PF01396 YP_001461445.1 identified by glimmer YP_001461446.1 identified by match to protein family HMM PF00589 YP_001461447.1 identified by match to protein family HMM PF02625 YP_001461448.1 identified by match to protein family HMM PF01315; match to protein family HMM PF02738 YP_001461449.1 identified by match to protein family HMM PF00941 YP_001461450.1 identified by match to protein family HMM PF00111; match to protein family HMM PF01799; match to protein family HMM TIGR01409 YP_001461451.1 identified by match to protein family HMM PF07274 YP_001461455.1 identified by similarity to GB:AAN78884.1 YP_001461457.1 identified by match to protein family HMM PF00196 YP_001461458.1 identified by glimmer YP_001461459.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif YP_001461460.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001461461.1 identified by glimmer YP_001461462.1 identified by glimmer YP_001461463.1 identified by glimmer YP_001461464.1 identified by glimmer YP_001461465.1 identified by similarity to SP:P36943; match to protein family HMM PF02369 YP_001461466.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445 YP_001461467.1 identified by match to protein family HMM PF00248 YP_001461468.1 identified by match to protein family HMM PF04224 YP_001461470.1 identified by match to protein family HMM PF07338 YP_001461471.1 Involved in disulfide oxidoreductase activity and electron transport YP_001461472.1 identified by glimmer YP_001461473.1 identified by match to protein family HMM PF00165 YP_001461474.1 identified by match to protein family HMM PF02754 YP_001461475.1 identified by match to protein family HMM PF02589; match to protein family HMM TIGR00273 YP_001461476.1 identified by similarity to GB:AAP15803.1; match to protein family HMM PF02589 YP_001461477.1 identified by glimmer YP_001461478.1 identified by similarity to GB:CAD02590.1 YP_001461479.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_001461480.1 catalyzes the formation of betaine from betaine aldehyde YP_001461481.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes YP_001461482.1 identified by match to protein family HMM PF03811 YP_001461483.1 identified by match to protein family HMM PF03400 YP_001461484.1 proton-motive-force-driven choline transporter YP_001461485.1 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; match to protein family HMM TIGR03304 YP_001461486.1 identified by match to protein family HMM PF00196; match to protein family HMM PF00563 YP_001461487.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001461488.1 identified by similarity to SP:P77219; match to protein family HMM PF06496 YP_001461489.1 identified by similarity to GB:AAN78919.1 YP_001461490.1 identified by match to protein family HMM PF00023 YP_001461491.1 identified by similarity to GB:AAZ87092.1 YP_001461492.1 identified by match to protein family HMM PF06263 YP_001461493.1 identified by match to protein family HMM PF06545 YP_001461494.1 yahI; identified by match to protein family HMM PF00696 YP_001461495.1 metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain YP_001461496.1 identified by match to protein family HMM PF06171 YP_001461497.1 identified by glimmer YP_001461499.1 identified by match to protein family HMM PF00005 YP_001461500.1 identified by match to protein family HMM PF02653 YP_001461501.1 identified by match to protein family HMM PF02653 YP_001461502.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001461503.1 identified by similarity to GB:AAZ87085.1 YP_001461504.1 yahN; identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949 YP_001461505.1 identified by match to protein family HMM PF07338 YP_001461506.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM PF06506; match to protein family HMM TIGR02329 YP_001461507.1 identified by glimmer YP_001461508.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_001461509.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity YP_001461510.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C YP_001461511.1 catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent YP_001461512.1 identified by match to protein family HMM PF02133; match to protein family HMM TIGR00800 YP_001461513.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_001461514.1 controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source YP_001461515.1 identified by glimmer YP_001461516.1 identified by match to protein family HMM PF00484 YP_001461517.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide YP_001461518.1 MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon; not essential YP_001461519.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments YP_001461520.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon YP_001461521.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer YP_001461522.1 activator of 3-phenylpropionic acid catabolism YP_001461523.1 catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate YP_001461524.1 catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase YP_001461525.1 identified by similarity to SP:P77044; match to protein family HMM PF00561 YP_001461526.1 catalyzes the formation of 2-keto-4-hydroxypentanoic acid from 2-hydroxypentadienoic acid YP_001461527.1 catalyzes the formation of acetyl-CoA from acetalaldehyde YP_001461528.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate YP_001461529.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00895 YP_001461531.1 identified by glimmer YP_001461532.1 identified by match to protein family HMM PF00756; match to protein family HMM TIGR02821 YP_001461533.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818 YP_001461534.1 formaldehyde-induced negative regulator of the frmRAB operon YP_001461535.1 yaiO; identified by glimmer YP_001461536.1 identified by match to protein family HMM PF00132 YP_001461537.1 yaiP; identified by match to protein family HMM PF00535 YP_001461538.1 yaiS; identified by match to protein family HMM PF02585 YP_001461539.1 identified by glimmer YP_001461540.1 identified by glimmer YP_001461541.1 with TauB and TauC is responsible for taurine uptake. YP_001461542.1 identified by match to protein family HMM PF00528 YP_001461543.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers YP_001461544.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001461545.1 IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats YP_001461546.1 IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats YP_001461547.1 identified by match to protein family HMM PF03797; match to protein family HMM TIGR01414; match to protein family HMM TIGR03304 YP_001461548.1 identified by similarity to SP:P0AAP5 YP_001461549.1 this protein has no known enzymatic function YP_001461550.1 identified by glimmer YP_001461551.1 identified by glimmer YP_001461552.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope YP_001461553.1 identified by match to protein family HMM PF07759 YP_001461554.1 identified by glimmer YP_001461555.1 identified by similarity to SP:P0AAP7 YP_001461556.1 identified by similarity to GB:AAZ87131.1 YP_001461557.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001461558.1 identified by glimmer YP_001461559.1 identified by glimmer YP_001461561.1 identified by similarity to SP:P00634; match to protein family HMM PF00245 YP_001461562.1 identified by match to protein family HMM PF07769 YP_001461563.1 catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis YP_001461564.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_001461565.1 identified by similarity to SP:Q3Z523; match to protein family HMM PF02639 YP_001461566.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001461568.1 identified by match to protein family HMM PF07302 YP_001461569.1 identified by match to protein family HMM PF06865 YP_001461570.1 ykiA; identified by glimmer YP_001461571.1 Required for efficient pilin antigenic variation YP_001461572.1 catalyzes phosphorylation of fructose; cytosolic enzyme YP_001461573.1 identified by glimmer YP_001461574.1 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers YP_001461575.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity YP_001461576.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity YP_001461577.1 identified by glimmer YP_001461578.1 two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB YP_001461579.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB YP_001461580.1 identified by glimmer YP_001461581.1 identified by similarity to GB:AAX64346.1 YP_001461582.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_001461583.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation YP_001461584.1 identified by similarity to SP:P21517; match to protein family HMM PF00128 YP_001461585.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP YP_001461586.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001461587.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001461588.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_001461589.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001461590.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001461591.1 identified by match to protein family HMM PF01844 YP_001461592.1 identified by similarity to GB:ABB67500.1 YP_001461593.1 identified by match to protein family HMM PF03502 YP_001461595.1 identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244 YP_001461596.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil YP_001461597.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001461598.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001461599.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_001461600.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate YP_001461601.1 identified by match to protein family HMM PF00248 YP_001461602.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001461603.1 identified by similarity to SP:P22939; match to protein family HMM PF00348 YP_001461604.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_001461605.1 identified by glimmer YP_001461606.1 Required for the synthesis of the thiazole moiety YP_001461607.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01383 YP_001461608.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_001461609.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_001461610.1 identified by match to protein family HMM PF07690 YP_001461611.1 identified by match to protein family HMM PF08238 YP_001461612.1 identified by match to protein family HMM PF00583 YP_001461613.1 identified by similarity to GB:AAZ87186.1; match to protein family HMM PF08681 YP_001461614.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001461615.1 identified by similarity to SP:P0ABJ6; match to protein family HMM PF03626; match to protein family HMM TIGR02847 YP_001461616.1 identified by similarity to SP:P0ABJ3; match to protein family HMM PF00510; match to protein family HMM TIGR02842 YP_001461617.1 identified by match to protein family HMM PF00115; match to protein family HMM TIGR02843 YP_001461618.1 identified by similarity to SP:P0ABJ1; match to protein family HMM PF00116; match to protein family HMM PF06481; match to protein family HMM TIGR01433 YP_001461619.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein YP_001461620.1 identified by match to protein family HMM PF03923 YP_001461621.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress YP_001461622.1 identified by glimmer YP_001461623.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001461624.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001461625.1 binds and unfolds substrates as part of the ClpXP protease YP_001461626.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02190; match to protein family HMM PF05362; match to protein family HMM PF07728; match to protein family HMM TIGR00763 YP_001461627.1 histone-like DNA-binding protein YP_001461628.1 identified by similarity to SP:P0ADY1; match to protein family HMM PF00639; match to protein family HMM PF09312 YP_001461629.1 identified by match to protein family HMM TIGR00426 YP_001461630.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00051 YP_001461631.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His YP_001461632.1 identified by match to protein family HMM PF00496 YP_001461633.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_001461634.1 identified by match to protein family HMM PF01037 YP_001461635.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_001461636.1 identified by similarity to SP:P0AAG5; match to protein family HMM PF00005; match to protein family HMM PF00664 YP_001461637.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia. YP_001461638.1 identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836 YP_001461639.1 identified by match to protein family HMM PF02551; match to protein family HMM TIGR00189 YP_001461641.1 identified by match to protein family HMM PF01035; match to protein family HMM TIGR00589 YP_001461642.1 identified by match to protein family HMM PF07237 YP_001461643.1 identified by match to protein family HMM PF00563 YP_001461645.1 identified by similarity to SP:P77791; match to protein family HMM PF00132 YP_001461646.1 identified by similarity to GB:ABB65073.1 YP_001461647.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_001461648.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730 YP_001461649.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine YP_001461650.1 identified by glimmer YP_001461651.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS YP_001461652.1 identified by glimmer YP_001461653.1 identified by similarity to RF:NP_455077.1 YP_001461654.1 PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks YP_001461655.1 identified by match to protein family HMM PF04304 YP_001461656.1 identified by glimmer YP_001461657.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001461658.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_001461659.1 identified by glimmer YP_001461660.1 identified by similarity to GB:AAZ90762.1; match to protein family HMM PF02575; match to protein family HMM TIGR00103 YP_001461661.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001461662.1 molecular chaperone YP_001461663.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001461664.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001461665.1 identified by similarity to SP:P23872; match to protein family HMM PF07859 YP_001461666.1 identified by similarity to SP:P0AEW6; match to protein family HMM PF00294 YP_001461667.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein YP_001461668.1 identified by match to protein family HMM PF07690 YP_001461669.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_001461670.1 identified by match to protein family HMM PF04073; match to protein family HMM TIGR00011 YP_001461671.1 identified by match to protein family HMM PF07446 YP_001461672.1 identified by match to protein family HMM PF01381; match to protein family HMM TIGR02607 YP_001461673.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525 YP_001461674.1 catalyzes the formation of glutamate from glutamine YP_001461675.1 identified by match to protein family HMM PF00324; match to protein family HMM PF01490; match to protein family HMM PF03845 YP_001461676.1 activator of copper-responsive regulon genes YP_001461677.1 identified by match to protein family HMM PF01957 YP_001461678.1 identified by match to protein family HMM PF01145 YP_001461679.1 identified by match to protein family HMM PF00005 YP_001461680.1 identified by match to protein family HMM PF03649; match to protein family HMM TIGR00245 YP_001461681.1 identified by similarity to SP:P77395; match to protein family HMM PF00085 YP_001461682.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_001461683.1 identified by similarity to SP:P0ADA1; match to protein family HMM PF00657 YP_001461684.1 identified by match to protein family HMM PF00005 YP_001461685.1 identified by match to protein family HMM PF02687 YP_001461686.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643 YP_001461688.1 identified by match to protein family HMM PF03527 YP_001461689.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_001461690.1 activator of the allDC-ylbA operon involved in allantoin utilization YP_001461691.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate YP_001461692.1 regulates operons involved in the utilization of allantoin YP_001461693.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate YP_001461694.1 identified by match to protein family HMM PF01261; match to protein family HMM TIGR03234 YP_001461695.1 identified by match to protein family HMM PF03446; match to protein family HMM TIGR01505 YP_001461696.1 identified by match to protein family HMM PF02133; match to protein family HMM TIGR00800 YP_001461697.1 Plays a crucial role on both purine and pyrimidine metabolism YP_001461698.1 identified by match to protein family HMM PF00860 YP_001461699.1 identified by glimmer YP_001461700.1 identified by similarity to SP:P77364; match to protein family HMM PF02595; match to protein family HMM TIGR00045 YP_001461701.1 identified by glimmer YP_001461702.1 identified by match to protein family HMM PF05899; match to protein family HMM PF07883; match to protein family HMM TIGR03214 YP_001461703.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001461704.1 identified by similarity to SP:P77555; match to protein family HMM PF02615; match to protein family HMM TIGR03175 YP_001461705.1 multicopy suppressor of dominant negative ftsH mutations YP_001461706.1 identified by match to protein family HMM PF06545 YP_001461707.1 ylbF; identified by similarity to GB:ABB65130.1 YP_001461708.1 identified by match to protein family HMM PF00696; match to protein family HMM TIGR00746 YP_001461709.1 identified by glimmer YP_001461710.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_001461711.1 identified by similarity to SP:P0AG18; match to protein family HMM PF00731; match to protein family HMM TIGR01162 YP_001461712.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_001461713.1 identified by similarity to SP:P23869; match to protein family HMM PF00160 YP_001461714.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001461715.1 identified by match to protein family HMM PF04307 YP_001461716.1 identified by similarity to SP:P0AAS8 YP_001461717.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001461718.1 identified by similarity to SP:P04128; match to protein family HMM PF00419 YP_001461719.1 identified by glimmer YP_001461720.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001461721.1 identified by glimmer YP_001461722.1 identified by similarity to GB:AAD17914.1 YP_001461723.1 activates the production of the major fimbrae protein FimA YP_001461724.1 identified by match to protein family HMM PF00165 YP_001461726.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719 YP_001461727.1 identified by match to protein family HMM PF01609 YP_001461728.1 identified by glimmer YP_001461729.1 identified by match to protein family HMM PF05488; match to protein family HMM PF05593; match to protein family HMM TIGR01643 YP_001461730.1 identified by similarity to GB:CAE12649.1; match to protein family HMM PF08786 YP_001461731.1 identified by match to protein family HMM PF04524; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361 YP_001461732.1 identified by similarity to SP:P77485; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR01386 YP_001461733.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system YP_001461734.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver YP_001461736.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver YP_001461737.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00914 YP_001461738.1 identified by match to protein family HMM PF00324 YP_001461739.1 identified by match to protein family HMM PF00924 YP_001461740.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive YP_001461741.1 identified by glimmer YP_001461742.1 identified by similarity to GB:BAA35219.1; match to protein family HMM PF04237 YP_001461743.1 identified by match to protein family HMM PF06643 YP_001461744.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity YP_001461745.1 identified by similarity to SP:P19925; match to protein family HMM PF01648 YP_001461746.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space YP_001461747.1 identified by similarity to SP:P13039; match to protein family HMM PF00756 YP_001461748.1 identified by match to protein family HMM PF03621 YP_001461749.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin YP_001461750.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake YP_001461751.1 with FepBDE is involved in the transport of ferric enterobactin YP_001461752.1 with FepBCD is involved in the transport of ferric enterobactin YP_001461753.1 with FepBCG is involved in the transport of ferric enterobactin YP_001461754.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters YP_001461755.1 with FepCDG is involved in the transport of ferric enterobactin YP_001461756.1 identified by similarity to SP:P0AEJ2; match to protein family HMM PF00425; match to protein family HMM TIGR00543 YP_001461757.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate YP_001461758.1 identified by similarity to SP:P0ADI4; match to protein family HMM PF00550; match to protein family HMM PF00857 YP_001461759.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin YP_001461760.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_001461761.1 identified by similarity to SP:P15078; match to protein family HMM PF02554 YP_001461762.1 identified by similarity to SP:P0AAT1; match to protein family HMM PF04328 YP_001461763.1 member of the iron-containing alcohol dehydrogenase; unknown function YP_001461764.1 catalyzes the transfer of an amino moiety YP_001461765.1 identified by match to protein family HMM PF02195 YP_001461766.1 identified by match to protein family HMM PF01507 YP_001461767.1 identified by match to protein family HMM PF00126 YP_001461768.1 Involved in disulfide bond formation YP_001461769.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate YP_001461770.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR03140 YP_001461771.1 identified by similarity to SP:P39177; match to protein family HMM PF00582 YP_001461772.1 identified by glimmer YP_001461773.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001461774.1 identified by glimmer YP_001461775.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation YP_001461776.1 identified by similarity to SP:P21338; match to protein family HMM PF00445 YP_001461777.1 identified by similarity to SP:P0AE74; match to protein family HMM PF00939; match to protein family HMM TIGR00785 YP_001461778.1 catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA YP_001461779.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate YP_001461780.1 identified by match to protein family HMM PF04223; match to protein family HMM TIGR01584 YP_001461781.1 identified by match to protein family HMM PF03328; match to protein family HMM TIGR01588 YP_001461782.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate YP_001461783.1 identified by glimmer YP_001461784.1 identified by similarity to SP:P77510; match to protein family HMM PF02518 YP_001461785.1 regulates the expression of citAB in citrate fermentation YP_001461786.1 responsible for the transport of C4-dicarboxylates during anaerobic growth YP_001461787.1 identified by glimmer YP_001461788.1 identified by glimmer YP_001461789.1 catalyzes the transfer of palmitate to lipid A YP_001461790.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator YP_001461791.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001461792.1 identified by match to protein family HMM PF00795 YP_001461793.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001461794.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001461795.1 identified by glimmer YP_001461796.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001461797.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_001461798.1 identified by similarity to SP:P0A8J4; match to protein family HMM PF04359 YP_001461799.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors YP_001461801.1 identified by similarity to SP:P10100; match to protein family HMM PF03330; match to protein family HMM PF05036; match to protein family HMM TIGR00413 YP_001461802.1 identified by similarity to SP:P0ABG7; match to protein family HMM PF01098; match to protein family HMM TIGR02210 YP_001461803.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM TIGR03423 YP_001461804.1 SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_001461805.1 identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090 YP_001461806.1 identified by similarity to SP:P52086; match to protein family HMM PF00300; match to protein family HMM TIGR03162 YP_001461807.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_001461808.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_001461809.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane YP_001461810.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001461811.1 identified by similarity to SP:P0AAT9; match to protein family HMM PF07295 YP_001461812.1 identified by similarity to GB:AAV88692.1; match to protein family HMM PF08238 YP_001461813.1 identified by glimmer YP_001461814.1 identified by glimmer YP_001461815.1 identified by similarity to SP:P77627; match to protein family HMM PF06889 YP_001461816.1 identified by match to protein family HMM PF00226 YP_001461817.1 identified by similarity to GB:BAB34108.1; match to protein family HMM PF08238 YP_001461818.1 identified by similarity to SP:P77427; match to protein family HMM PF06889 YP_001461819.1 identified by match to protein family HMM PF00226 YP_001461820.1 identified by match to protein family HMM PF00012 YP_001461821.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific YP_001461822.1 identified by match to protein family HMM PF00005 YP_001461823.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001461824.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001461825.1 identified by match to protein family HMM PF00497 YP_001461826.1 identified by glimmer YP_001461827.1 identified by match to protein family HMM PF01694; match to protein family HMM TIGR02276 YP_001461828.1 Transfers the fatty acyl group on membrane lipoproteins YP_001461829.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471 YP_001461830.1 identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043 YP_001461831.1 identified by match to protein family HMM PF02562 YP_001461832.1 identified by glimmer YP_001461833.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001461834.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q YP_001461835.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_001461836.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01460 YP_001461837.1 identified by match to protein family HMM PF00480 YP_001461838.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate YP_001461839.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_001461840.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001461841.1 identified by glimmer YP_001461842.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001461843.1 identified by glimmer YP_001461844.1 identified by glimmer YP_001461845.1 identified by match to protein family HMM PF03573 YP_001461847.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_001461848.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001461849.1 identified by match to protein family HMM PF01402 YP_001461850.1 identified by match to protein family HMM PF00561; match to protein family HMM PF07819 YP_001461851.1 negative modulator of the initiation of chromosome replication YP_001461852.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001461853.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system YP_001461854.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_001461855.1 identified by similarity to GB:AAN42241.1 YP_001461856.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport YP_001461857.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein YP_001461858.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex YP_001461859.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001461860.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001461861.1 identified by match to protein family HMM TIGR02115 YP_001461862.1 identified by similarity to GB:AAN79258.1 YP_001461863.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643 YP_001461864.1 identified by match to protein family HMM PF03527 YP_001461865.1 identified by glimmer YP_001461866.1 identified by similarity to GB:BAA35363.1 YP_001461867.1 identified by similarity to GB:AAN79259.1; match to protein family HMM PF08349 YP_001461868.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent YP_001461869.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924 YP_001461870.1 identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486 YP_001461871.1 identified by match to protein family HMM PF02682; match to protein family HMM TIGR00370 YP_001461872.1 identified by match to protein family HMM PF02626; match to protein family HMM TIGR00724 YP_001461873.1 identified by match to protein family HMM PF03746 YP_001461874.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity YP_001461875.1 identified by similarity to GB:AAZ87425.1 YP_001461876.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001461877.1 identified by match to protein family HMM PF00577 YP_001461878.1 identified by similarity to SP:P04128; match to protein family HMM PF00419 YP_001461879.1 identified by glimmer YP_001461880.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_001461881.1 identified by match to protein family HMM PF01127; match to protein family HMM TIGR02970 YP_001461882.1 identified by match to protein family HMM TIGR02968 YP_001461883.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001461884.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001461885.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001461886.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_001461887.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001461888.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_001461889.1 regulates the succiny-lCoA synthetase operon YP_001461890.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001461891.1 identified by match to protein family HMM PF01074; match to protein family HMM PF07748 YP_001461892.1 identified by glimmer YP_001461893.1 identified by match to protein family HMM PF01654 YP_001461894.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203 YP_001461895.1 identified by match to protein family HMM PF08173; match to protein family HMM TIGR02106 YP_001461896.1 identified by match to protein family HMM TIGR02112 YP_001461897.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components YP_001461898.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_001461899.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_001461900.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins YP_001461901.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_001461902.1 identified by match to protein family HMM PF00691; match to protein family HMM TIGR02802 YP_001461903.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity YP_001461904.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001461905.1 identified by match to protein family HMM PF04973; match to protein family HMM TIGR01528 YP_001461906.1 involved in zinc efflux across the cytoplasmic membrane YP_001461908.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001461909.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_001461910.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose YP_001461911.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism YP_001461912.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P YP_001461913.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF05368; match to protein family HMM PF07993; match to protein family HMM TIGR01179 YP_001461914.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum YP_001461915.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons YP_001461917.1 with ModCB is involved in the high-affinity transport of molybdate YP_001461918.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE YP_001461919.1 Part of the ABC transporter complex modABC involved in molybdenum import YP_001461920.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily YP_001461921.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate YP_001461922.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001461923.1 identified by similarity to SP:P0AAV8; match to protein family HMM PF04303 YP_001461924.1 identified by match to protein family HMM PF00939; match to protein family HMM PF03600; match to protein family HMM TIGR00785 YP_001461925.1 identified by match to protein family HMM PF00330; match to protein family HMM PF00694 YP_001461926.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase YP_001461927.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899; match to protein family HMM PF09003 YP_001461928.1 identified by match to protein family HMM PF01258; match to protein family HMM TIGR02419 YP_001461929.1 identified by glimmer YP_001461930.1 identified by similarity to GB:BAB34229.1 YP_001461931.1 identified by similarity to SP:P03697 YP_001461932.1 identified by similarity to SP:P03698; match to protein family HMM PF03837; match to protein family HMM TIGR01913 YP_001461933.1 identified by similarity to SP:P03702; match to protein family HMM PF06064 YP_001461934.1 identified by similarity to SP:P38393 YP_001461935.1 identified by match to protein family HMM PF00717; match to protein family HMM PF01381 YP_001461936.1 identified by match to protein family HMM PF06254 YP_001461937.1 identified by match to protein family HMM PF06992 YP_001461939.1 member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation YP_001461940.1 identified by match to protein family HMM PF03050 YP_001461941.1 identified by match to protein family HMM PF05717 YP_001461942.1 identified by match to protein family HMM PF01527 YP_001461943.1 identified by glimmer YP_001461944.1 DLP12 prophage YP_001461945.1 identified by match to protein family HMM PF07102 YP_001461946.1 DLP12 prophage; Holliday junction resolvase YP_001461947.1 identified by similarity to SP:Q47272 YP_001461948.1 identified by similarity to SP:Q47274; match to protein family HMM PF06530 YP_001461949.1 identified by similarity to SP:P07238; match to protein family HMM PF00267 YP_001461950.1 identified by glimmer YP_001461951.1 identified by match to protein family HMM PF04971 YP_001461952.1 identified by match to protein family HMM PF00959 YP_001461953.1 identified by match to protein family HMM PF03245 YP_001461954.1 identified by match to protein family HMM PF04383 YP_001461955.1 identified by glimmer YP_001461956.1 identified by match to protein family HMM PF07471 YP_001461957.1 identified by match to protein family HMM PF05876 YP_001461958.1 identified by match to protein family HMM PF03335; match to protein family HMM PF07484 YP_001461959.1 identified by similarity to SP:P03740; match to protein family HMM PF02413 YP_001461960.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001461961.1 YbhB; similar to rat and human kinase inhibitory proteins YP_001461962.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_001461963.1 identified by similarity to SP:P12996; match to protein family HMM PF04055; match to protein family HMM PF06968; match to protein family HMM TIGR00433 YP_001461964.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_001461965.1 methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth YP_001461966.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_001461967.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001461968.1 identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826 YP_001461969.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001461970.1 identified by similarity to SP:P30746; match to protein family HMM PF00994; match to protein family HMM TIGR00177; match to protein family HMM TIGR02667 YP_001461971.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001461972.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_001461973.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_001461974.1 identified by match to protein family HMM PF01027 YP_001461975.1 identified by glimmer YP_001461976.1 ybhM; identified by match to protein family HMM PF01027 YP_001461978.1 identified by match to protein family HMM PF00614 YP_001461979.1 identified by glimmer YP_001461980.1 identified by match to protein family HMM PF03372 YP_001461982.1 identified by match to protein family HMM PF01061 YP_001461983.1 identified by match to protein family HMM PF01061 YP_001461984.1 identified by match to protein family HMM PF00005 YP_001461985.1 identified by match to protein family HMM PF00529 YP_001461986.1 identified by match to protein family HMM PF00440; match to protein family HMM PF09209 YP_001461987.1 this helicase is not essential cell growth YP_001461988.1 identified by glimmer YP_001461989.1 identified by glimmer YP_001461990.1 identified by similarity to GB:CAD72180.1; match to protein family HMM PF08719; match to protein family HMM TIGR02464 YP_001461991.1 helicase involved in DNA repair and perhaps also replication YP_001461992.1 identified by match to protein family HMM PF02885 YP_001461993.1 identified by glimmer YP_001461994.1 identified by similarity to PDB:2G8Y_A; match to protein family HMM PF02615 YP_001461995.1 identified by match to protein family HMM PF07338 YP_001461996.1 identified by match to protein family HMM PF01258 YP_001461997.1 identified by match to protein family HMM PF03171 YP_001461998.1 Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein YP_001461999.1 identified by glimmer YP_001462000.1 identified by match to protein family HMM PF07338 YP_001462001.1 identified by match to protein family HMM PF05971 YP_001462002.1 identified by match to protein family HMM PF00924 YP_001462003.1 similar to ATP-binding component of ABC transporters YP_001462004.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine YP_001462005.1 similar to periplasmic-binding component of ABC transporters YP_001462006.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage YP_001462007.1 identified by glimmer YP_001462008.1 identified by similarity to SP:P0AA67; match to protein family HMM PF00892 YP_001462009.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains YP_001462010.1 identified by match to protein family HMM PF00884 YP_001462012.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present YP_001462013.1 identified by match to protein family HMM PF03600 YP_001462014.1 identified by similarity to SP:P0AAX8; match to protein family HMM PF03734 YP_001462015.1 identified by match to protein family HMM PF00005 YP_001462016.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001462017.1 identified by match to protein family HMM PF07350 YP_001462018.1 identified by similarity to SP:P75792; match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_001462019.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01774 YP_001462020.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494 YP_001462021.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies YP_001462022.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_001462023.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum YP_001462024.1 identified by similarity to SP:P37595; match to protein family HMM PF01112 YP_001462025.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains YP_001462026.1 identified by similarity to SP:P75797; match to protein family HMM PF00496 YP_001462027.1 identified by similarity to SP:P75798; match to protein family HMM PF00528 YP_001462028.1 identified by similarity to SP:P75799; match to protein family HMM PF00528 YP_001462029.1 identified by match to protein family HMM PF00563 YP_001462030.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001462031.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_001462032.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_001462033.1 identified by similarity to SP:P75804; match to protein family HMM PF07995 YP_001462034.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_001462035.1 penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_001462036.1 identified by similarity to SP:P0ACK5; match to protein family HMM PF00455; match to protein family HMM PF08220 YP_001462037.1 identified by match to protein family HMM PF01569 YP_001462038.1 identified by glimmer YP_001462039.1 identified by match to protein family HMM PF07690 YP_001462041.1 identified by similarity to SP:P75809; match to protein family HMM PF00702; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_001462042.1 identified by match to protein family HMM PF07690 YP_001462043.1 identified by match to protein family HMM PF00440 YP_001462044.1 identified by match to protein family HMM PF02080; match to protein family HMM PF06826; match to protein family HMM TIGR01625 YP_001462046.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_001462047.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function YP_001462048.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds YP_001462049.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 YP_001462051.1 identified by match to protein family HMM PF01547 YP_001462052.1 part of the PotFGHI ATP-dependent putrescine transporter YP_001462053.1 identified by match to protein family HMM PF00528 YP_001462054.1 identified by match to protein family HMM PF00528 YP_001462056.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_001462057.1 identified by glimmer YP_001462058.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_001462059.1 with ArtPQJI acts to transport arginine across the inner membrane YP_001462060.1 with ArtPMJI transports arginine across the inner membrane YP_001462061.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_001462062.1 With ArtMQJI transports arginine across the inner membrane YP_001462063.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS YP_001462064.1 identified by match to protein family HMM PF01906 YP_001462065.1 identified by similarity to SP:P75820; match to protein family HMM PF01510 YP_001462066.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF07993 YP_001462067.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF05368 YP_001462068.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine YP_001462069.1 catalyzes the formation of acetate from pyruvate YP_001462070.1 identified by similarity to SP:P75824; match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970 YP_001462071.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_001462072.1 identified by match to protein family HMM PF03956 YP_001462073.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure YP_001462074.1 identified by similarity to GB:ABG68906.1 YP_001462075.1 identified by match to protein family HMM PF04393 YP_001462076.1 confers macrolide resistance via active drug efflux YP_001462077.1 inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible YP_001462078.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001462079.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates YP_001462080.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001462081.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001462082.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001462083.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001462084.1 identified by glimmer YP_001462085.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding YP_001462086.1 identified by glimmer YP_001462087.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_001462088.1 DNA-binding membrane protein required for chromosome resolution and partitioning YP_001462089.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_001462090.1 identified by similarity to SP:P0AAZ4; match to protein family HMM PF00004 YP_001462091.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001462092.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_001462093.1 identified by similarity to SP:P18776; match to protein family HMM PF00037; match to protein family HMM TIGR02951 YP_001462094.1 identified by glimmer YP_001462095.1 identified by similarity to SP:P18777; match to protein family HMM PF04976 YP_001462096.1 identified by match to protein family HMM PF00857 YP_001462097.1 identified by glimmer YP_001462098.1 identified by match to protein family HMM PF07690 YP_001462099.1 identified by match to protein family HMM PF00324 YP_001462100.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001462101.1 identified by glimmer YP_001462102.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358 YP_001462103.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_001462104.1 identified by match to protein family HMM PF00589 YP_001462105.1 identified by similarity to SP:P07695 YP_001462106.1 identified by similarity to SP:P07696 YP_001462107.1 identified by similarity to GB:AAL21618.1 YP_001462109.1 identified by match to protein family HMM PF01258; match to protein family HMM TIGR02419 YP_001462111.1 identified by similarity to SP:Q06419; match to protein family HMM PF05840 YP_001462112.1 identified by similarity to GB:ABB41600.1 YP_001462113.1 identified by match to protein family HMM PF04860 YP_001462115.1 identified by similarity to SP:P15025; match to protein family HMM PF00665 YP_001462116.1 identified by match to protein family HMM PF00308; match to protein family HMM PF01695 YP_001462118.1 identified by match to protein family HMM PF06995 YP_001462119.1 identified by match to protein family HMM PF05954 YP_001462120.1 in E. coli K-12 this is in prophage P2 remnant YP_001462121.1 identified by similarity to SP:P09373; match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255 YP_001462122.1 identified by match to protein family HMM PF01226; match to protein family HMM TIGR00790 YP_001462123.1 identified by similarity to GB:AAP16417.1; match to protein family HMM PF02624; match to protein family HMM TIGR00702 YP_001462124.1 identified by match to protein family HMM PF04239 YP_001462125.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_001462126.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001462127.1 ycaL; identified by match to protein family HMM PF01435 YP_001462128.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001462129.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001462130.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001462131.1 ycaI; identified by match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361 YP_001462132.1 involved in the transport of lipid A across the inner membrane YP_001462133.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_001462134.1 identified by match to protein family HMM PF06224 YP_001462135.1 identified by similarity to GB:AAX64850.1; match to protein family HMM PF03966 YP_001462136.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001462138.1 identified by match to protein family HMM PF02698 YP_001462139.1 identified by glimmer YP_001462140.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA YP_001462141.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division YP_001462142.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division YP_001462143.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects YP_001462144.1 identified by match to protein family HMM PF01471 YP_001462145.1 identified by match to protein family HMM PF05951; match to protein family HMM PF08291; match to protein family HMM TIGR01409 YP_001462146.1 identified by match to protein family HMM PF00753 YP_001462147.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001462148.1 identified by glimmer YP_001462149.1 outer membrane porin F; 1a; Ia; b YP_001462150.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001462151.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_001462152.1 identified by match to protein family HMM PF01433; match to protein family HMM TIGR02414 YP_001462153.1 identified by glimmer YP_001462154.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease YP_001462155.1 part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease YP_001462156.1 catalyzes the release of sulfite from alkanesulfonates YP_001462159.1 identified by match to protein family HMM PF02413 YP_001462160.1 identified by match to protein family HMM PF02413 YP_001462161.1 identified by match to protein family HMM PF03406 YP_001462163.1 identified by match to protein family HMM PF04865 YP_001462164.1 identified by match to protein family HMM PF07409 YP_001462165.1 identified by match to protein family HMM PF06890; match to protein family HMM TIGR01644 YP_001462166.1 identified by match to protein family HMM PF06893 YP_001462167.1 identified by similarity to SP:P07636; match to protein family HMM PF02316; match to protein family HMM PF02914; match to protein family HMM PF09039; match to protein family HMM PF09299 YP_001462168.1 identified by match to protein family HMM PF02316 YP_001462169.1 identified by match to protein family HMM PF04069; match to protein family HMM TIGR01728 YP_001462170.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358 YP_001462171.1 identified by match to protein family HMM PF00419 YP_001462172.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001462173.1 identified by similarity to SP:P30130; match to protein family HMM PF00577 YP_001462174.1 identified by match to protein family HMM PF00419 YP_001462175.1 identified by match to protein family HMM PF00419 YP_001462176.1 identified by match to protein family HMM PF00419 YP_001462177.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001462178.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001462179.1 identified by match to protein family HMM PF07126 YP_001462180.1 identified by match to protein family HMM PF00111; match to protein family HMM PF03473; match to protein family HMM PF03476 YP_001462181.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_001462182.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_001462183.1 identified by similarity to SP:P43670; match to protein family HMM PF04403; match to protein family HMM TIGR00155 YP_001462184.1 identified by similarity to SP:P43671; match to protein family HMM PF02470 YP_001462185.1 identified by match to protein family HMM PF03886 YP_001462186.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_001462188.1 identified by match to protein family HMM PF06303 YP_001462189.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d YP_001462190.1 identified by glimmer YP_001462191.1 identified by match to protein family HMM PF03846; match to protein family HMM TIGR00623 YP_001462192.1 identified by match to protein family HMM PF04993; match to protein family HMM PF04994 YP_001462193.1 identified by match to protein family HMM PF05976; match to protein family HMM TIGR01666; match to protein family HMM TIGR01667 YP_001462194.1 identified by match to protein family HMM PF03733 YP_001462195.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand YP_001462196.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_001462198.1 identified by match to protein family HMM PF02629 YP_001462199.1 identified by similarity to SP:P0AB20; match to protein family HMM PF08755; match to protein family HMM TIGR02097 YP_001462200.1 identified by match to protein family HMM PF03602 YP_001462201.1 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs YP_001462202.1 identified by match to protein family HMM PF01027 YP_001462203.1 identified by match to protein family HMM PF01058; match to protein family HMM PF08425; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409 YP_001462204.1 involved in hydrogen cycling during fermentative growth YP_001462205.1 identified by match to protein family HMM PF01292; match to protein family HMM TIGR02125 YP_001462206.1 HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1) YP_001462207.1 involved in processing hydrogenases HyaA and HyaB YP_001462208.1 identified by similarity to SP:P19932; match to protein family HMM PF04809 YP_001462209.1 identified by match to protein family HMM PF01654 YP_001462210.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203 YP_001462211.1 expressed during stationary phase YP_001462212.1 identified by similarity to SP:P07102; match to protein family HMM PF00328 YP_001462213.1 identified by similarity to SP:P38134; match to protein family HMM PF02706 YP_001462214.1 Etk and Etp are a tyrosine kinase-tyrosine phosphatase pair, etp dephosphorylates etk YP_001462215.1 identified by match to protein family HMM PF02563 YP_001462216.1 identified by match to protein family HMM PF06082 YP_001462217.1 identified by match to protein family HMM PF06251 YP_001462219.1 identified by similarity to SP:P75885 YP_001462220.1 identified by match to protein family HMM PF00313 YP_001462221.1 identified by match to protein family HMM PF00313 YP_001462222.1 identified by match to protein family HMM PF08178 YP_001462223.1 identified by glimmer YP_001462224.1 yccM; identified by match to protein family HMM PF00037 YP_001462225.1 identified by glimmer YP_001462226.1 Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide YP_001462227.1 periplasmic sensory protein associated with the TorRS two-component regulatory system YP_001462228.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes YP_001462229.1 identified by similarity to SP:P33226; match to protein family HMM PF03264; match to protein family HMM TIGR02162 YP_001462230.1 identified by similarity to SP:P33225; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; match to protein family HMM TIGR01409; match to protein family HMM TIGR02164 YP_001462231.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor YP_001462232.1 identified by glimmer YP_001462233.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA YP_001462234.1 functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock YP_001462235.1 identified by similarity to GB:AAP16515.1 YP_001462236.1 identified by similarity to SP:P19926; match to protein family HMM PF00328 YP_001462238.1 stationary phase that binds TrpR repressor YP_001462239.1 identified by similarity to GB:BAA35782.1 YP_001462240.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801 YP_001462241.1 identified by similarity to SP:P75893; match to protein family HMM PF01613 YP_001462242.1 identified by similarity to SP:P75894; match to protein family HMM PF00881 YP_001462243.1 identified by similarity to SP:P75895; match to protein family HMM PF00561 YP_001462244.1 identified by similarity to SP:P0AFQ5; match to protein family HMM PF01042 YP_001462245.1 identified by similarity to SP:P75897; match to protein family HMM PF00857 YP_001462246.1 identified by similarity to SP:P75898; match to protein family HMM PF00296 YP_001462247.1 identified by similarity to SP:P0ACU2; match to protein family HMM PF00440; match to protein family HMM PF08362 YP_001462248.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein YP_001462250.1 identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813; match to protein family HMM TIGR02121 YP_001462251.1 identified by match to protein family HMM PF03239; match to protein family HMM TIGR00145 YP_001462252.1 identified by match to protein family HMM PF04302 YP_001462253.1 identified by match to protein family HMM PF04261; match to protein family HMM TIGR01409; match to protein family HMM TIGR01412; match to protein family HMM TIGR01413 YP_001462254.1 identified by glimmer YP_001462255.1 in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export YP_001462256.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein YP_001462257.1 in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export YP_001462258.1 outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia YP_001462259.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001462260.1 identified by similarity to SP:P05822; match to protein family HMM PF00665 YP_001462261.1 identified by match to protein family HMM PF01527 YP_001462262.1 identified by glimmer YP_001462264.1 identified by glimmer YP_001462265.1 identified by match to protein family HMM PF02811 YP_001462266.1 identified by match to protein family HMM PF06192 YP_001462267.1 identified by match to protein family HMM PF06496 YP_001462268.1 identified by match to protein family HMM PF03783 YP_001462269.1 nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex YP_001462270.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex YP_001462271.1 activates the csgBA and csgDEFG operons involved in biofilm formation YP_001462272.1 identified by glimmer YP_001462273.1 CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface YP_001462274.1 identified by similarity to SP:P28307; match to protein family HMM PF07012 YP_001462275.1 involved in autoagglutination of curliated cells; not involved in production of curli fibers YP_001462277.1 identified by match to protein family HMM PF01661 YP_001462278.1 identified by match to protein family HMM PF00614 YP_001462279.1 required for the transfer of succinyl residues to the glucan backbone YP_001462280.1 identified by glimmer YP_001462281.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_001462282.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_001462283.1 identified by match to protein family HMM PF07119 YP_001462285.1 Confers resistance to fosfomycin and deoxycholate YP_001462286.1 identified by glimmer YP_001462287.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_001462288.1 identified by match to protein family HMM PF00581 YP_001462289.1 identified by match to protein family HMM PF04264 YP_001462290.1 identified by match to protein family HMM PF01292 YP_001462292.1 identified by similarity to RF:NP_460130.1 YP_001462293.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids YP_001462294.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_001462295.1 identified by similarity to SP:P0ABR4; match to protein family HMM PF06183 YP_001462296.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001462297.1 identified by match to protein family HMM PF07273 YP_001462298.1 cofactor involved in the reduction of disulfides YP_001462299.1 Confers resistance to norfloxacin and enoxacin YP_001462300.1 identified by similarity to SP:P0A948; match to protein family HMM PF00583 YP_001462301.1 identified by match to protein family HMM PF04337 YP_001462302.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_001462303.1 identified by match to protein family HMM PF03023; match to protein family HMM TIGR01695 YP_001462304.1 identified by match to protein family HMM PF05130 YP_001462305.1 regulates the flagellar specific sigma28 transcription factor YP_001462306.1 required for the assembly of the flagellar basal body P-ring YP_001462307.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella YP_001462308.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_001462309.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_001462310.1 the hook connects flagellar basal body to the flagellar filament YP_001462311.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_001462312.1 makes up the distal portion of the flagellar basal body rod YP_001462313.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_001462314.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001462315.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_001462316.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_001462317.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes YP_001462318.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase YP_001462319.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA YP_001462320.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001462321.1 identified by match to protein family HMM PF02620 YP_001462322.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001462323.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001462324.1 identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128 YP_001462325.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001462326.1 carries the fatty acid chain in fatty acid biosynthesis YP_001462327.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001462328.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate YP_001462329.1 identified by match to protein family HMM PF02618; match to protein family HMM TIGR00247 YP_001462330.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_001462331.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_001462332.1 identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010 YP_001462333.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001462334.1 identified by similarity to SP:P16869; match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783 YP_001462336.1 identified by similarity to SP:P0ACE7; match to protein family HMM PF01230 YP_001462337.1 identified by match to protein family HMM PF07233 YP_001462338.1 identified by match to protein family HMM TIGR02722 YP_001462339.1 catalyzes the phosphorylation of thiamine to thiamine phosphate YP_001462340.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_001462341.1 identified by match to protein family HMM PF05728 YP_001462342.1 identified by similarity to SP:P00393; match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF07992 YP_001462343.1 identified by match to protein family HMM PF05433 YP_001462344.1 identified by match to protein family HMM PF00440 YP_001462345.1 identified by match to protein family HMM PF07338 YP_001462346.1 identified by match to protein family HMM PF01476; match to protein family HMM PF03734 YP_001462347.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580 YP_001462348.1 identified by match to protein family HMM PF01757 YP_001462349.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_001462350.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone YP_001462351.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_001462352.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine YP_001462355.1 identified by glimmer YP_001462356.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate YP_001462357.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component YP_001462358.1 identified by match to protein family HMM PF00589; match to protein family HMM PF09003 YP_001462359.1 identified by similarity to SP:P27079 YP_001462362.1 identified by similarity to GB:AAN79873.1; match to protein family HMM PF07358 YP_001462363.1 identified by match to protein family HMM PF05358 YP_001462364.1 identified by glimmer YP_001462365.1 identified by glimmer YP_001462366.1 identified by match to protein family HMM PF07151 YP_001462367.1 identified by similarity to GB:AAK16987.1 YP_001462368.1 identified by similarity to GB:AAN79880.1; match to protein family HMM PF06254 YP_001462369.1 identified by similarity to SP:P03688 YP_001462370.1 identified by similarity to SP:P0AEF0; match to protein family HMM PF01695 YP_001462371.1 identified by similarity to GB:AAG56436.1; match to protein family HMM PF07789 YP_001462372.1 identified by match to protein family HMM PF06163 YP_001462373.1 identified by similarity to GB:BAB34936.1 YP_001462374.1 identified by glimmer YP_001462376.1 identified by similarity to GB:AAZ88571.1; match to protein family HMM PF06914 YP_001462377.1 identified by similarity to SP:Q9MCN8; match to protein family HMM PF05866 YP_001462378.1 identified by match to protein family HMM PF06323 YP_001462379.1 identified by match to protein family HMM PF00069 YP_001462380.1 identified by glimmer YP_001462382.1 identified by match to protein family HMM PF01555 YP_001462383.1 identified by similarity to GB:CAC83546.1 YP_001462384.1 identified by similarity to GB:AAO06087.1; match to protein family HMM PF05449 YP_001462386.1 identified by glimmer YP_001462388.1 identified by match to protein family HMM PF07471 YP_001462389.1 identified by match to protein family HMM PF06316; match to protein family HMM TIGR03304 YP_001462390.1 identified by match to protein family HMM PF03335; match to protein family HMM PF03406; match to protein family HMM PF07484; match to protein family HMM PF08400 YP_001462391.1 identified by similarity to SP:P03740; match to protein family HMM PF02413 YP_001462392.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_001462393.1 identified by glimmer YP_001462394.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component YP_001462395.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase YP_001462396.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_001462397.1 identified by match to protein family HMM PF08007 YP_001462398.1 identified by similarity to SP:P23837; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF08918 YP_001462399.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress YP_001462400.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001462401.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_001462402.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001462403.1 identified by match to protein family HMM PF00293 YP_001462404.1 catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA YP_001462405.1 Converts isocitrate to alpha ketoglutarate YP_001462406.1 identified by match to protein family HMM PF07166 YP_001462407.1 identified by similarity to SP:P33358; match to protein family HMM PF00376 YP_001462408.1 identified by glimmer YP_001462409.1 identified by match to protein family HMM PF00563; match to protein family HMM PF04940 YP_001462410.1 identified by similarity to SP:P75992 YP_001462413.1 identified by match to protein family HMM PF00563 YP_001462414.1 ymgF YP_001462415.1 identified by glimmer YP_001462416.1 identified by glimmer YP_001462417.1 identified by glimmer YP_001462418.1 identified by match to protein family HMM PF03797; match to protein family HMM TIGR01414; match to protein family HMM TIGR03304 YP_001462419.1 ymgD; identified by glimmer YP_001462420.1 identified by similarity to GB:ABB13223.1 YP_001462421.1 identified by glimmer YP_001462422.1 identified by glimmer YP_001462423.1 identified by glimmer YP_001462424.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_001462425.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums YP_001462426.1 blocks the formation of polar Z-ring septums YP_001462427.1 identified by match to protein family HMM PF05666 YP_001462428.1 identified by match to protein family HMM PF04151 YP_001462429.1 identified by match to protein family HMM PF05166 YP_001462430.1 identified by match to protein family HMM PF01557 YP_001462431.1 identified by match to protein family HMM PF03692 YP_001462432.1 identified by glimmer YP_001462433.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization YP_001462434.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization YP_001462435.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_001462436.1 involved in regulation of intracellular pH under alkaline conditions YP_001462437.1 Multifunctional regulator of fatty acid metabolism YP_001462438.1 identified by match to protein family HMM PF04293 YP_001462439.1 catalyzes the oxidative deamination of D-amino acids YP_001462440.1 catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA YP_001462441.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_001462442.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine YP_001462443.1 identified by similarity to SP:P76009; match to protein family HMM PF01464 YP_001462444.1 identified by match to protein family HMM PF07238; match to protein family HMM PF07317 YP_001462445.1 identified by match to protein family HMM PF04226 YP_001462446.1 identified by similarity to GB:AAT83486.1 YP_001462447.1 identified by similarity to GB:ABB66472.1 YP_001462448.1 periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell YP_001462449.1 phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL YP_001462450.1 with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone YP_001462451.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase YP_001462452.1 Positively regulates the dhaKLM operon from a sigma-70 promoter YP_001462453.1 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414 YP_001462454.1 identified by similarity to GB:AAZ88642.1 YP_001462455.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001462456.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001462457.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function YP_001462458.1 role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport YP_001462459.1 identified by glimmer YP_001462460.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001462461.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_001462462.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_001462463.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001462464.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001462465.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB YP_001462466.1 identified by match to protein family HMM PF04247 YP_001462468.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001462469.1 identified by similarity to GB:AAZ88629.1 YP_001462470.1 identified by similarity to GB:AAZ88629.1 YP_001462471.1 identified by match to protein family HMM PF01699; match to protein family HMM TIGR00846 YP_001462472.1 in Escherichia coli this protein ly regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions YP_001462473.1 identified by match to protein family HMM PF04752 YP_001462474.1 identified by match to protein family HMM PF02635 YP_001462476.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase YP_001462477.1 identified by similarity to SP:P10956; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF07730 YP_001462478.1 identified by glimmer YP_001462479.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00886 YP_001462480.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580 YP_001462481.1 identified by similarity to SP:P11349; match to protein family HMM PF00037; match to protein family HMM TIGR01660 YP_001462482.1 identified by similarity to SP:P0AF26; match to protein family HMM PF02613; match to protein family HMM TIGR00684 YP_001462483.1 identified by similarity to SP:P11350; match to protein family HMM PF02665; match to protein family HMM TIGR00351 YP_001462484.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001462485.1 identified by match to protein family HMM PF02810 YP_001462486.1 identified by match to protein family HMM PF01734 YP_001462487.1 identified by match to protein family HMM PF00072 YP_001462488.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_001462489.1 identified by similarity to SP:P0ACF8; match to protein family HMM PF00816 YP_001462490.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_001462491.1 identified by similarity to SP:P0A9Q7; match to protein family HMM PF00171; match to protein family HMM PF00465 YP_001462492.1 identified by match to protein family HMM PF01914; match to protein family HMM TIGR00427 YP_001462493.1 identified by match to protein family HMM PF00496 YP_001462494.1 identified by match to protein family HMM PF00528 YP_001462495.1 identified by match to protein family HMM PF00528 YP_001462496.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_001462497.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_001462498.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein YP_001462499.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_001462500.1 identified by similarity to SP:P31069; match to protein family HMM PF02254; match to protein family HMM PF07885 YP_001462501.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_001462503.1 identified by similarity to GB:AAZ87752.1 YP_001462504.1 identified by glimmer YP_001462506.1 identified by match to protein family HMM TIGR02675 YP_001462507.1 identified by match to protein family HMM PF01527 YP_001462508.1 identified by match to protein family HMM PF05717 YP_001462509.1 identified by match to protein family HMM PF03050 YP_001462511.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508 YP_001462512.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins YP_001462513.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase of proteins YP_001462514.1 Involved in cell division; probably involved in intracellular septation YP_001462515.1 identified by match to protein family HMM PF06790 YP_001462516.1 receptor for colicin S4 YP_001462517.1 identified by match to protein family HMM PF00589; match to protein family HMM PF09003 YP_001462518.1 identified by match to protein family HMM PF00929 YP_001462519.1 identified by glimmer YP_001462520.1 identified by match to protein family HMM PF07358 YP_001462521.1 identified by match to protein family HMM TIGR02681 YP_001462522.1 identified by similarity to GB:CAD05612.1 YP_001462523.1 identified by match to protein family HMM PF07151 YP_001462524.1 identified by similarity to SP:P06965 YP_001462525.1 identified by match to protein family HMM PF06254 YP_001462526.1 identified by similarity to GB:AAW62196.1 YP_001462528.1 identified by similarity to GB:BAB35696.1; match to protein family HMM PF06163 YP_001462530.1 identified by similarity to GB:BAB35372.1 YP_001462531.1 identified by similarity to GB:CAD05601.1 YP_001462532.1 identified by glimmer YP_001462533.1 identified by similarity to GB:ABB61576.1 YP_001462534.1 identified by similarity to GB:AAN79892.1; match to protein family HMM PF06914 YP_001462535.1 identified by similarity to SP:Q9MCN8; match to protein family HMM PF05866 YP_001462536.1 identified by match to protein family HMM PF06323 YP_001462537.1 identified by match to protein family HMM PF00069 YP_001462538.1 identified by glimmer YP_001462539.1 identified by similarity to GB:CAE15837.1 YP_001462540.1 identified by match to protein family HMM PF01555 YP_001462541.1 identified by similarity to GB:CAB93764.1 YP_001462542.1 identified by glimmer YP_001462543.1 identified by match to protein family HMM PF05136 YP_001462545.1 identified by glimmer YP_001462548.1 identified by glimmer YP_001462549.1 identified by glimmer YP_001462550.1 identified by match to protein family HMM PF02413 YP_001462552.1 identified by match to protein family HMM TIGR03304 YP_001462553.1 identified by match to protein family HMM PF05974 YP_001462554.1 identified by match to protein family HMM PF05974 YP_001462555.1 identified by similarity to GB:AAX64977.1 YP_001462556.1 identified by similarity to OMNI:NTL01EC01230 YP_001462557.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001462558.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001462559.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_001462560.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis YP_001462561.1 identified by glimmer YP_001462562.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_001462563.1 identified by match to protein family HMM PF02811 YP_001462564.1 identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057 YP_001462565.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA YP_001462566.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_001462567.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_001462568.1 SohB; periplasmic protein; member of the peptidase S49 family YP_001462569.1 identified by glimmer YP_001462571.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001462572.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_001462575.1 Catalyzes the conversion of citrate to isocitrate YP_001462576.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_001462577.1 identified by similarity to SP:P0A924; match to protein family HMM PF01569 YP_001462578.1 identified by match to protein family HMM PF06305 YP_001462579.1 identified by match to protein family HMM PF07719 YP_001462580.1 identified by glimmer YP_001462581.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001462582.1 involved in start site selection during the initiation of translation YP_001462583.1 identified by similarity to SP:P0ADA7 YP_001462584.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_001462586.1 c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP YP_001462587.1 identified by glimmer YP_001462588.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction YP_001462590.1 identified by glimmer YP_001462591.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_001462592.1 identified by glimmer YP_001462593.1 identified by match to protein family HMM PF04480 YP_001462594.1 identified by match to protein family HMM PF00005 YP_001462595.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_001462596.1 identified by match to protein family HMM PF00528 YP_001462597.1 identified by match to protein family HMM PF00528 YP_001462598.1 identified by match to protein family HMM PF00496 YP_001462599.1 identified by glimmer YP_001462601.1 identified by glimmer YP_001462602.1 identified by match to protein family HMM PF00324 YP_001462603.1 identified by similarity to SP:P78061; match to protein family HMM PF00120 YP_001462604.1 identified by glimmer YP_001462605.1 catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate YP_001462606.1 regulates genes involved in putrescine degradation YP_001462607.1 catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation YP_001462608.1 identified by similarity to SP:P37906; match to protein family HMM PF01266 YP_001462609.1 putrescine-inducible GABA aminotransferase; catalyzes the formation of glutamate and succinate semialdehyde from 4-aminobutyrate and 2-oxoglutarate YP_001462610.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor YP_001462611.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF YP_001462612.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding YP_001462613.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock YP_001462614.1 identified by match to protein family HMM TIGR02979 YP_001462615.1 rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide YP_001462616.1 identified by match to protein family HMM PF00128 YP_001462617.1 identified by match to protein family HMM PF01547 YP_001462618.1 identified by match to protein family HMM PF00528 YP_001462619.1 identified by match to protein family HMM PF00528 YP_001462620.1 identified by match to protein family HMM PF00107 YP_001462621.1 identified by match to protein family HMM PF01261 YP_001462622.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_001462623.1 identified by match to protein family HMM PF03632; match to protein family HMM PF03633; match to protein family HMM PF03636 YP_001462624.1 identified by glimmer YP_001462625.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; match to protein family HMM TIGR01990; match to protein family HMM TIGR02009 YP_001462626.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402 YP_001462627.1 identified by match to protein family HMM TIGR03304 YP_001462628.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001462629.1 identified by match to protein family HMM PF04317 YP_001462630.1 identified by similarity to GB:ABB66349.1; match to protein family HMM PF05128; match to protein family HMM TIGR01620 YP_001462631.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids YP_001462632.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_001462633.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_001462634.1 identified by match to protein family HMM PF00246 YP_001462635.1 identified by match to protein family HMM PF05368 YP_001462636.1 identified by similarity to GB:BAC59941.1 YP_001462638.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001462639.1 identified by match to protein family HMM PF00496 YP_001462640.1 identified by match to protein family HMM PF00924 YP_001462641.1 with UspC and UspD is involved in resistance to UV irradiation YP_001462642.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_001462643.1 identified by similarity to SP:P46133; match to protein family HMM PF03806; match to protein family HMM TIGR00819 YP_001462644.1 identified by similarity to SP:P76052; match to protein family HMM PF01546; match to protein family HMM TIGR01891 YP_001462645.1 identified by similarity to SP:P77357; match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891 YP_001462646.1 identified by glimmer YP_001462647.1 identified by glimmer YP_001462648.1 identified by similarity to SP:P77744; match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001462649.1 identified by match to protein family HMM PF01713 YP_001462650.1 identified by match to protein family HMM PF00990; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254 YP_001462651.1 identified by match to protein family HMM PF01544 YP_001462652.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_001462653.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_001462654.1 identified by similarity to SP:P37903; match to protein family HMM PF00582 YP_001462655.1 identified by similarity to SP:P77747; match to protein family HMM PF00267 YP_001462656.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176 YP_001462657.1 identified by glimmer YP_001462659.1 identified by match to protein family HMM PF03724 YP_001462660.1 identified by similarity to SP:P52643; match to protein family HMM PF00389; match to protein family HMM PF02826 YP_001462661.1 identified by similarity to SP:P52645 YP_001462663.1 identified by similarity to GB:AAN80294.1; match to protein family HMM PF07027 YP_001462664.1 activator of genes involved in phenylacetic acid catabolism YP_001462665.1 identified by similarity to SP:P80668; match to protein family HMM PF00171 YP_001462666.1 catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine YP_001462667.1 catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA YP_001462668.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA YP_001462669.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation YP_001462670.1 identified by match to protein family HMM PF05138; match to protein family HMM TIGR02158 YP_001462671.1 identified by match to protein family HMM PF01883; match to protein family HMM TIGR02159 YP_001462672.1 identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM TIGR02160 YP_001462673.1 identified by match to protein family HMM PF00378 YP_001462674.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001462675.1 converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation YP_001462676.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; match to protein family HMM TIGR02286 YP_001462677.1 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA YP_001462678.1 identified by match to protein family HMM TIGR02155 YP_001462679.1 identified by glimmer YP_001462680.1 identified by similarity to SP:P76086; match to protein family HMM PF07848; match to protein family HMM PF08223; match to protein family HMM TIGR02277 YP_001462681.1 identified by match to protein family HMM PF00132; match to protein family HMM TIGR02287 YP_001462682.1 identified by match to protein family HMM PF00248 YP_001462683.1 identified by match to protein family HMM PF01066 YP_001462684.1 identified by match to protein family HMM PF01148 YP_001462686.1 identified by match to protein family HMM PF00782; match to protein family HMM PF01569 YP_001462687.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_001462688.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain YP_001462689.1 identified by match to protein family HMM PF02698 YP_001462690.1 NAD-linked YP_001462691.1 identified by similarity to SP:P33898; match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534 YP_001462692.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm YP_001462694.1 identified by similarity to SP:P05704; match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203 YP_001462695.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001462696.1 identified by similarity to SP:P15747; match to protein family HMM PF07063 YP_001462697.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans YP_001462698.1 identified by similarity to GB:AAN80313.1; match to protein family HMM PF04325 YP_001462699.1 identified by similarity to SP:P13857; match to protein family HMM PF00583 YP_001462700.1 identified by similarity to SP:P15644 YP_001462701.1 identified by similarity to SP:P25396; match to protein family HMM PF03595; match to protein family HMM TIGR00816 YP_001462702.1 with TehA confers resistance to tellurite YP_001462704.1 identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766 YP_001462705.1 identified by match to protein family HMM PF00860; match to protein family HMM PF03594; match to protein family HMM TIGR00843 YP_001462706.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883 YP_001462707.1 identified by match to protein family HMM PF01136 YP_001462709.1 identified by similarity to GB:AAN80324.1 YP_001462710.1 identified by match to protein family HMM PF01381; match to protein family HMM PF03681 YP_001462711.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_001462712.1 identified by match to protein family HMM PF01547 YP_001462713.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08402 YP_001462714.1 identified by match to protein family HMM PF00528 YP_001462715.1 identified by match to protein family HMM PF00528 YP_001462716.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation YP_001462717.1 identified by glimmer YP_001462719.1 identified by glimmer YP_001462721.1 identified by match to protein family HMM PF04657 YP_001462722.1 identified by match to protein family HMM PF00583 YP_001462723.1 identified by match to protein family HMM PF00107 YP_001462724.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_001462725.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR03304 YP_001462726.1 identified by glimmer YP_001462728.1 identified by match to protein family HMM PF00324 YP_001462729.1 identified by glimmer YP_001462730.1 identified by match to protein family HMM PF04524; match to protein family HMM PF06715; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361 YP_001462731.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643 YP_001462732.1 identified by glimmer YP_001462733.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown YP_001462734.1 identified by match to protein family HMM PF01613 YP_001462735.1 identified by match to protein family HMM PF00797 YP_001462736.1 identified by match to protein family HMM PF02567; match to protein family HMM TIGR00654 YP_001462737.1 identified by similarity to SP:P11350; match to protein family HMM PF02665; match to protein family HMM TIGR00351 YP_001462738.1 identified by similarity to SP:P19317; match to protein family HMM PF02613; match to protein family HMM TIGR00684 YP_001462739.1 identified by similarity to SP:P19318; match to protein family HMM TIGR01660 YP_001462740.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580 YP_001462741.1 identified by similarity to SP:P37758; match to protein family HMM PF07690; match to protein family HMM TIGR00886 YP_001462742.1 identified by similarity to SP:P76123 YP_001462744.1 identified by match to protein family HMM PF00892 YP_001462745.1 identified by similarity to SP:P24183; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01553 YP_001462746.1 identified by similarity to SP:P0AAJ3; match to protein family HMM PF00037; match to protein family HMM PF09163; match to protein family HMM TIGR01582 YP_001462747.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase YP_001462748.1 identified by match to protein family HMM PF01381; match to protein family HMM TIGR02607 YP_001462749.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs YP_001462750.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_001462751.1 protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase YP_001462752.1 identified by similarity to SP:P76127 YP_001462753.1 identified by match to protein family HMM PF02566 YP_001462754.1 catalyzes the formation of acetoacetate from 3-hydroxybutyrate YP_001462755.1 identified by match to protein family HMM PF03600 YP_001462756.1 identified by match to protein family HMM PF00725; match to protein family HMM PF02737 YP_001462757.1 identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930 YP_001462758.1 identified by match to protein family HMM PF01144; match to protein family HMM TIGR02428 YP_001462759.1 identified by similarity to SP:Q01103; match to protein family HMM PF01144; match to protein family HMM TIGR02429 YP_001462760.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001462761.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_001462762.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_001462763.1 identified by similarity to SP:P77463; match to protein family HMM PF00528 YP_001462764.1 identified by match to protein family HMM PF00528 YP_001462765.1 catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis YP_001462766.1 heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate YP_001462767.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001462768.1 identified by match to protein family HMM PF02638 YP_001462769.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR00910 YP_001462770.1 identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788 YP_001462771.1 identified by glimmer YP_001462772.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193 YP_001462773.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR03304 YP_001462774.1 identified by match to protein family HMM PF00005; match to protein family HMM PF05992 YP_001462775.1 ydeM; identified by match to protein family HMM PF04055 YP_001462776.1 regulates the cellular response to acid resistance YP_001462777.1 in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase YP_001462778.1 identified by similarity to SP:P08191; match to protein family HMM PF00419; match to protein family HMM PF09160 YP_001462779.1 identified by similarity to SP:P08190; match to protein family HMM PF00419 YP_001462780.1 identified by match to protein family HMM PF00419 YP_001462781.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001462782.1 identified by glimmer YP_001462783.1 identified by glimmer YP_001462784.1 identified by match to protein family HMM PF00263; match to protein family HMM PF03958 YP_001462785.1 identified by glimmer YP_001462786.1 identified by glimmer YP_001462787.1 identified by glimmer YP_001462788.1 identified by glimmer YP_001462789.1 identified by glimmer YP_001462790.1 identified by glimmer YP_001462791.1 identified by match to protein family HMM PF02486 YP_001462792.1 identified by glimmer YP_001462793.1 identified by glimmer YP_001462794.1 identified by glimmer YP_001462795.1 identified by similarity to SP:P23873; match to protein family HMM PF01381 YP_001462796.1 identified by glimmer YP_001462797.1 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; match to protein family HMM TIGR03304 YP_001462798.1 identified by similarity to SP:P77432; match to protein family HMM PF00370; match to protein family HMM PF02782 YP_001462799.1 identified by similarity to SP:P76141; match to protein family HMM PF04198 YP_001462800.1 identified by similarity to SP:P77257; match to protein family HMM PF00005 YP_001462801.1 identified by similarity to SP:P0AFS1 YP_001462802.1 identified by similarity to SP:P76142 YP_001462803.1 identified by similarity to SP:P76143; match to protein family HMM PF01791 YP_001462804.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate YP_001462805.1 identified by match to protein family HMM PF05249 YP_001462806.1 catalyzes the formation of D-tagaturonate from D-altronate YP_001462807.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001462808.1 identified by similarity to GB:ABB61754.1 YP_001462809.1 catalyzes the formation of glutamate from glutamine YP_001462810.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase YP_001462811.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001462812.1 identified by glimmer YP_001462813.1 identified by similarity to SP:Q9S3J9; match to protein family HMM PF07690 YP_001462814.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function YP_001462815.1 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes YP_001462816.1 transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF YP_001462817.1 identified by similarity to SP:P31121 YP_001462818.1 converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism YP_001462819.1 identified by similarity to SP:P26218; match to protein family HMM PF02264 YP_001462820.1 identified by match to protein family HMM PF02255 YP_001462821.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410 YP_001462822.1 identified by match to protein family HMM PF02302 YP_001462823.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_001462824.1 identified by match to protein family HMM PF00892; match to protein family HMM PF03151 YP_001462825.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters YP_001462826.1 identified by similarity to GB:AAV77284.1 YP_001462827.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001462828.1 identified by match to protein family HMM PF04076; match to protein family HMM TIGR00156 YP_001462829.1 identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199 YP_001462830.1 identified by similarity to SP:P24171; match to protein family HMM PF01432 YP_001462831.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine YP_001462832.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_001462833.1 identified by similarity to SP:P64466 YP_001462834.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_001462835.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_001462836.1 identified by similarity to SP:P76154 YP_001462837.1 identified by match to protein family HMM PF00239; match to protein family HMM PF02796 YP_001462838.1 identified by similarity to SP:P03740; match to protein family HMM PF02413 YP_001462840.1 identified by match to protein family HMM PF03050 YP_001462841.1 identified by match to protein family HMM PF05717 YP_001462842.1 identified by match to protein family HMM PF01527 YP_001462843.1 identified by match to protein family HMM PF03050 YP_001462844.1 identified by match to protein family HMM PF05717 YP_001462845.1 identified by match to protein family HMM PF01527 YP_001462846.1 identified by match to protein family HMM PF04971 YP_001462847.1 identified by glimmer YP_001462848.1 identified by match to protein family HMM PF00313 YP_001462849.1 identified by match to protein family HMM PF03589 YP_001462850.1 identified by similarity to SP:P76162; match to protein family HMM PF06914 YP_001462852.1 identified by glimmer YP_001462854.1 identified by match to protein family HMM PF01527 YP_001462855.1 identified by match to protein family HMM PF06163 YP_001462856.1 identified by similarity to SP:P03688 YP_001462857.1 identified by similarity to GB:BAB35190.1; match to protein family HMM PF06254 YP_001462858.1 identified by similarity to SP:P06965 YP_001462859.1 identified by glimmer YP_001462860.1 identified by match to protein family HMM PF07151 YP_001462861.1 identified by glimmer YP_001462862.1 identified by similarity to SP:P09557; match to protein family HMM PF05358 YP_001462863.1 identified by match to protein family HMM PF07358 YP_001462864.1 identified by match to protein family HMM PF00929 YP_001462865.1 identified by glimmer YP_001462866.1 identified by match to protein family HMM PF06806 YP_001462867.1 identified by match to protein family HMM PF00589 YP_001462868.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001462869.1 identified by similarity to SP:P38104; match to protein family HMM PF01188; match to protein family HMM PF02746 YP_001462870.1 identified by match to protein family HMM PF02694 YP_001462871.1 identified by match to protein family HMM PF06932 YP_001462872.1 identified by similarity to SP:P0A951; match to protein family HMM PF00583 YP_001462873.1 identified by match to protein family HMM PF06788 YP_001462874.1 identified by match to protein family HMM PF06649 YP_001462875.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_001462876.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_001462877.1 identified by similarity to SP:P18776; match to protein family HMM PF00037; match to protein family HMM TIGR02951 YP_001462878.1 identified by match to protein family HMM PF04976 YP_001462879.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane YP_001462880.1 identified by match to protein family HMM PF00654 YP_001462881.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_001462882.1 identified by similarity to SP:P50456; match to protein family HMM PF00480 YP_001462883.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001462884.1 identified by match to protein family HMM PF07690 YP_001462885.1 required for growth and survival under moderately acid conditions YP_001462886.1 identified by match to protein family HMM PF00089 YP_001462887.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS YP_001462888.1 with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS YP_001462889.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes YP_001462890.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme YP_001462891.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_001462892.1 identified by glimmer YP_001462893.1 identified by match to protein family HMM PF07338 YP_001462894.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR00905 YP_001462895.1 identified by match to protein family HMM PF00106 YP_001462896.1 identified by match to protein family HMM PF06942 YP_001462897.1 response regulator in two-component regulatory system with RstB YP_001462898.1 identified by similarity to SP:P18392; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_001462899.1 binds to DNA replication terminator sequences to prevent passage of replication forks YP_001462900.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_001462901.1 identified by similarity to SP:P0AC33; match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723 YP_001462902.1 identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218 YP_001462903.1 identified by match to protein family HMM PF06097 YP_001462904.1 identified by similarity to SP:Q47706; match to protein family HMM PF03573 YP_001462905.1 identified by similarity to SP:P30868; match to protein family HMM PF07690; match to protein family HMM TIGR00792 YP_001462906.1 identified by similarity to SP:P05804; match to protein family HMM PF00703; match to protein family HMM PF02836; match to protein family HMM PF02837 YP_001462907.1 identified by match to protein family HMM PF00440 YP_001462908.1 Acts on the hydroxyl group at position 7 of the steroid frame YP_001462909.1 regulates malXY which are involved in maltose-glucose transport YP_001462910.1 phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site YP_001462911.1 identified by similarity to SP:P23256; match to protein family HMM PF00155 YP_001462912.1 catalyzes the formation of inosine from adenosine YP_001462913.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894 YP_001462914.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes YP_001462916.1 identified by match to protein family HMM PF02508; match to protein family HMM TIGR01943 YP_001462917.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001462918.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001462919.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_001462920.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_001462921.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_001462922.1 identified by glimmer YP_001462923.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines YP_001462924.1 identified by glimmer YP_001462925.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation YP_001462926.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_001462927.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_001462928.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001462929.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_001462930.1 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme YP_001462931.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_001462932.1 identified by similarity to SP:P0A1X0; match to protein family HMM PF05433 YP_001462933.1 Transcription regulator that can both activate or repress expression YP_001462934.1 identified by glimmer YP_001462935.1 identified by match to protein family HMM PF07869 YP_001462936.1 identified by match to protein family HMM PF00529 YP_001462937.1 identified by match to protein family HMM PF04632 YP_001462938.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water YP_001462939.1 identified by similarity to SP:P76187; match to protein family HMM PF00248 YP_001462940.1 identified by glimmer YP_001462941.1 identified by match to protein family HMM PF00440 YP_001462942.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide YP_001462943.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione YP_001462944.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_001462945.1 identified by glimmer YP_001462946.1 similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases; longest known protein in E. coli YP_001462947.1 identified by similarity to SP:P0AC69; match to protein family HMM PF00462; match to protein family HMM TIGR00365 YP_001462948.1 identified by glimmer YP_001462949.1 identified by match to protein family HMM PF00877 YP_001462950.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals YP_001462951.1 identified by match to protein family HMM PF07690 YP_001462952.1 identified by glimmer YP_001462953.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers YP_001462954.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001462955.1 uncharacterized member of the major facilitator superfamily (MFS) YP_001462956.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_001462957.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001462958.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_001462960.1 identified by glimmer YP_001462961.1 identified by similarity to GB:AAV79142.1; match to protein family HMM PF08803 YP_001462962.1 identified by similarity to GB:AAZ88190.1 YP_001462963.1 identified by match to protein family HMM PF01292 YP_001462964.1 identified by match to protein family HMM PF00037 YP_001462965.1 identified by similarity to GB:AAZ88187.1 YP_001462966.1 identified by match to protein family HMM PF01314; match to protein family HMM PF02730 YP_001462967.1 identified by match to protein family HMM PF00037 YP_001462968.1 identified by glimmer YP_001462970.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001462971.1 identified by similarity to SP:P69776; match to protein family HMM PF04728 YP_001462972.1 identified by match to protein family HMM PF01476; match to protein family HMM PF03734 YP_001462973.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine YP_001462974.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine YP_001462975.1 with SufBC activates cysteine desulfurase SufS YP_001462976.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE YP_001462977.1 with SufCD activates cysteine desulfurase SufS YP_001462978.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein YP_001462979.1 identified by similarity to SP:P64478 YP_001462980.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_001462981.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913 YP_001462982.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function YP_001462983.1 identified by similarity to GB:ABB61800.1; match to protein family HMM PF08965 YP_001462984.1 identified by match to protein family HMM PF07690 YP_001462985.1 identified by match to protein family HMM PF07690 YP_001462986.1 YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate YP_001462987.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis YP_001462988.1 identified by match to protein family HMM PF01144 YP_001462989.1 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain YP_001462990.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02311; match to protein family HMM PF07883 YP_001462991.1 identified by glimmer YP_001462992.1 YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain YP_001462993.1 May play a role in a redox process YP_001462994.1 identified by similarity to SP:P68644; match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM PF03486 YP_001462996.1 acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids YP_001462997.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001462999.1 identified by similarity to SP:Q8ZDY4; match to protein family HMM PF03618 YP_001463000.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_001463001.1 identified by similarity to GB:ABB66046.1 YP_001463002.1 identified by similarity to SP:Q8Z6I8; match to protein family HMM PF02696 YP_001463003.1 identified by glimmer YP_001463004.1 identified by similarity to GB:AAP17004.1 YP_001463005.1 identified by match to protein family HMM PF00877 YP_001463006.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell YP_001463007.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane YP_001463008.1 with BtuD and BtuF transports vitamin B12 into the cell YP_001463009.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001463010.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001463011.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001463012.1 identified by glimmer YP_001463013.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001463014.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_001463015.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001463016.1 identified by glimmer YP_001463017.1 identified by match to protein family HMM PF04338 YP_001463018.1 identified by glimmer YP_001463019.1 identified by similarity to SP:P06999; match to protein family HMM PF00294; match to protein family HMM TIGR03168 YP_001463020.1 identified by similarity to SP:P64479 YP_001463021.1 identified by match to protein family HMM PF01636; match to protein family HMM PF03881 YP_001463022.1 identified by similarity to GB:AAZ88138.1 YP_001463023.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate YP_001463024.1 identified by match to protein family HMM PF04307 YP_001463025.1 identified by glimmer YP_001463026.1 identified by match to protein family HMM PF00375 YP_001463027.1 identified by similarity to SP:P0AE60 YP_001463028.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide YP_001463029.1 identified by similarity to GB:BAB92994.1; match to protein family HMM PF04794 YP_001463030.1 identified by similarity to SP:P17411; match to protein family HMM PF02056 YP_001463031.1 represses the celABCDF-ydjC operon involved in carbon uptake YP_001463032.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001463033.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001463034.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001463035.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein YP_001463036.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001463037.1 3' incision activity; acts with UvrC YP_001463038.1 identified by match to protein family HMM PF05962 YP_001463039.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP YP_001463040.1 identified by glimmer YP_001463041.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_001463042.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_001463043.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_001463044.1 identified by match to protein family HMM PF04958; match to protein family HMM TIGR03244 YP_001463045.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate YP_001463046.1 identified by glimmer YP_001463047.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_001463048.1 identified by match to protein family HMM PF09335 YP_001463049.1 identified by similarity to GB:AAZ88114.1 YP_001463050.1 identified by similarity to SP:P76221; match to protein family HMM PF09335 YP_001463051.1 identified by match to protein family HMM PF02627 YP_001463054.1 identified by match to protein family HMM PF00005 YP_001463056.1 identified by match to protein family HMM PF01066 YP_001463057.1 identified by similarity to SP:P77788; match to protein family HMM PF00293 YP_001463058.1 identified by match to protein family HMM PF07383 YP_001463059.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_001463060.1 identified by similarity to GB:AAN43058.1 YP_001463061.1 decatenates replicating daughter chromosomes YP_001463062.1 catalyzes the formation of selenophosphate from selenide and ATP YP_001463063.1 identified by match to protein family HMM PF00881 YP_001463064.1 identified by glimmer YP_001463065.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane YP_001463066.1 converts asparagine to aspartate and ammonia YP_001463067.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide YP_001463068.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_001463069.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_001463070.1 identified by match to protein family HMM PF00248 YP_001463071.1 identified by match to protein family HMM PF00294 YP_001463072.1 identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167 YP_001463073.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001463074.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_001463075.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001463076.1 identified by match to protein family HMM PF07023 YP_001463077.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_001463078.1 identified by similarity to SP:P0A9B2; match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534 YP_001463079.1 identified by match to protein family HMM PF01263 YP_001463080.1 identified by match to protein family HMM PF00248 YP_001463081.1 identified by similarity to SP:P0A908; match to protein family HMM PF06629 YP_001463082.1 identified by match to protein family HMM PF06798; match to protein family HMM PF08298 YP_001463083.1 identified by match to protein family HMM PF04285 YP_001463084.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001463085.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001463086.1 identified by match to protein family HMM PF04073 YP_001463087.1 identified by similarity to GB:AAZ88084.1 YP_001463088.1 identified by similarity to SP:P0ACY8; match to protein family HMM PF04284 YP_001463089.1 identified by similarity to SP:P76242; match to protein family HMM PF07690; match to protein family HMM TIGR00896 YP_001463090.1 identified by match to protein family HMM PF04343 YP_001463091.1 identified by match to protein family HMM PF03891 YP_001463092.1 identified by match to protein family HMM PF00990; match to protein family HMM PF01590; match to protein family HMM TIGR00254 YP_001463093.1 identified by glimmer YP_001463094.1 identified by match to protein family HMM PF04226 YP_001463095.1 identified by glimmer YP_001463096.1 identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766 YP_001463097.1 identified by match to protein family HMM PF01797 YP_001463098.1 identified by match to protein family HMM PF01810 YP_001463099.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001463100.1 identified by similarity to SP:Q51945; match to protein family HMM PF00180; match to protein family HMM TIGR02089 YP_001463101.1 member of the betaine, carnitine, choline transporter (BCCT) family; unknown function YP_001463102.1 identified by match to protein family HMM PF00355 YP_001463103.1 identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970 YP_001463104.1 identified by match to protein family HMM PF00570; match to protein family HMM PF01612; match to protein family HMM TIGR01388 YP_001463105.1 Activates fatty acids by binding to coenzyme A YP_001463106.1 identified by similarity to SP:P37194; match to protein family HMM PF03843; match to protein family HMM TIGR00752 YP_001463107.1 identified by match to protein family HMM PF00814 YP_001463109.1 identified by glimmer YP_001463110.1 identified by match to protein family HMM PF01042 YP_001463111.1 identified by glimmer YP_001463112.1 identified by similarity to SP:P64492; match to protein family HMM PF08986 YP_001463113.1 identified by similarity to SP:P67338; match to protein family HMM PF03701 YP_001463114.1 identified by similarity to SP:P05041; match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553 YP_001463115.1 identified by match to protein family HMM PF00293 YP_001463116.1 identified by similarity to SP:P16095; match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720 YP_001463117.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471; match to protein family HMM PF03741 YP_001463118.1 identified by match to protein family HMM PF03610; match to protein family HMM PF03830; match to protein family HMM TIGR00824; match to protein family HMM TIGR00854 YP_001463119.1 identified by match to protein family HMM PF03609; match to protein family HMM TIGR00822 YP_001463120.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel YP_001463121.1 identified by similarity to SP:Q8ZP01; match to protein family HMM PF06173 YP_001463122.1 membrane protein YebN YP_001463123.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth YP_001463124.1 identified by similarity to SP:P0A9Y6; match to protein family HMM PF00313 YP_001463125.1 identified by similarity to SP:P64511 YP_001463126.1 identified by similarity to SP:P64499 YP_001463128.1 identified by similarity to GB:ABB62074.1 YP_001463129.1 identified by similarity to SP:P76268; match to protein family HMM PF01614; match to protein family HMM PF09339 YP_001463130.1 identified by match to protein family HMM PF07690 YP_001463131.1 metalloprotease YP_001463132.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_001463133.1 affects solute and DNA transport through an unknown mechanism YP_001463134.1 identified by match to protein family HMM PF01590 YP_001463135.1 identified by match to protein family HMM PF04403; match to protein family HMM TIGR00155 YP_001463136.1 identified by match to protein family HMM PF02470 YP_001463137.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_001463138.1 identified by match to protein family HMM PF07351 YP_001463139.1 identified by match to protein family HMM PF07358 YP_001463140.1 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins YP_001463141.1 identified by similarity to GB:ABB61282.1 YP_001463142.1 identified by match to protein family HMM PF05425 YP_001463143.1 identified by match to protein family HMM PF04234 YP_001463144.1 identified by similarity to SP:P0ABT1; match to protein family HMM PF06440 YP_001463145.1 identified by match to protein family HMM PF00795 YP_001463146.1 3'-5' exonuclease activity on single or double-strand DNA YP_001463147.1 PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues YP_001463148.1 identified by match to protein family HMM PF04391 YP_001463149.1 identified by glimmer YP_001463150.1 secreted protein; unknown function YP_001463151.1 identified by similarity to SP:P0ACY9; match to protein family HMM PF07130 YP_001463152.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_001463153.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_001463154.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_001463155.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001463156.1 Represses the expression of the zwf, eda, glp and gap YP_001463157.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001463158.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_001463159.1 identified by match to protein family HMM PF01476; match to protein family HMM PF01551; match to protein family HMM PF04225; match to protein family HMM PF08525 YP_001463160.1 involved in transport of zinc(II) with ZnuA and C YP_001463161.1 involved in transport of zinc(II) with ZnuA and C YP_001463162.1 involved in transport of zinc(II) with ZnuA and C YP_001463163.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001463164.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001463165.1 identified by match to protein family HMM PF06520 YP_001463166.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001463167.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033 YP_001463168.1 converts dATP to dAMP and pyrophosphate YP_001463169.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001463170.1 identified by glimmer YP_001463171.1 identified by match to protein family HMM PF00857 YP_001463172.1 identified by similarity to SP:P37348; match to protein family HMM PF01904 YP_001463173.1 identified by similarity to SP:P64515 YP_001463174.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242; match to protein family HMM TIGR00740 YP_001463175.1 identified by match to protein family HMM PF08003; match to protein family HMM PF08241; match to protein family HMM TIGR00452 YP_001463176.1 identified by glimmer YP_001463177.1 identified by similarity to SP:P46923; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; match to protein family HMM TIGR01409 YP_001463178.1 identified by similarity to SP:P52005; match to protein family HMM PF03264 YP_001463179.1 identified by match to protein family HMM PF03932 YP_001463180.1 identified by similarity to GB:AAL20824.1; match to protein family HMM PF06185 YP_001463181.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001463182.1 identified by match to protein family HMM PF07007 YP_001463183.1 identified by similarity to SP:P76297; match to protein family HMM PF06366 YP_001463184.1 membrane protein involved in the flagellar export apparatus YP_001463185.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_001463186.1 identified by glimmer YP_001463187.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation YP_001463188.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble YP_001463189.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_001463190.1 methylates the MCP YP_001463191.1 mediates taxis toward dipeptides YP_001463192.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203 YP_001463193.1 identified by match to protein family HMM PF01584 YP_001463194.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component YP_001463195.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001463196.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001463197.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems YP_001463198.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems YP_001463199.1 identified by glimmer YP_001463200.1 ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_001463201.1 identified by match to protein family HMM PF00982; match to protein family HMM TIGR02400 YP_001463202.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature YP_001463203.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001463204.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001463205.1 identified by match to protein family HMM PF00532 YP_001463206.1 identified by match to protein family HMM PF00210 YP_001463208.1 identified by glimmer YP_001463210.1 identified by glimmer YP_001463211.1 cytoplasmic iron storage protein YP_001463212.1 identified by similarity to SP:P46887 YP_001463213.1 identified by match to protein family HMM PF01490; match to protein family HMM PF03222; match to protein family HMM TIGR00837 YP_001463214.1 identified by match to protein family HMM PF02810; match to protein family HMM TIGR02292 YP_001463215.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560 YP_001463216.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001463217.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_001463219.1 identified by similarity to SP:P0AD09 YP_001463220.1 regulates genes involved in cell division YP_001463221.1 identified by match to protein family HMM PF00005 YP_001463222.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001463223.1 catalyzes the formation of pyruvate from D-cysteine YP_001463224.1 identified by match to protein family HMM PF00497 YP_001463225.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence YP_001463226.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001463227.1 identified by glimmer YP_001463228.1 structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes YP_001463229.1 involved in flagellin assembly YP_001463230.1 flagellin specific chaperone YP_001463231.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family YP_001463232.1 converts 1,4-alpha-D-glucans to maltodextrin YP_001463234.1 identified by match to protein family HMM PF04143 YP_001463235.1 identified by match to protein family HMM PF01206 YP_001463236.1 identified by similarity to GB:AAG56946.1; match to protein family HMM PF02586 YP_001463237.1 identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766 YP_001463239.1 forms a junction between the M-ring and FlgB during flagella biosynthesis YP_001463240.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001463241.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001463242.1 binds to and inhibits the function of flagella specific ATPase FliI YP_001463243.1 involved in type III protein export during flagellum assembly YP_001463244.1 rod/hook and filament chaperone YP_001463245.1 identified by similarity to SP:P52614; match to protein family HMM PF02120 YP_001463246.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_001463247.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_001463248.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001463249.1 with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus YP_001463250.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001463251.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_001463252.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_001463253.1 identified by match to protein family HMM PF00196 YP_001463254.1 identified by similarity to OMNI:NTL01SF1877 YP_001463256.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate YP_001463257.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001463258.1 identified by similarity to GB:AAP17372.1 YP_001463259.1 identified by match to protein family HMM PF05661 YP_001463260.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950 YP_001463261.1 identified by similarity to SP:P09184; match to protein family HMM PF03852; match to protein family HMM TIGR00632 YP_001463262.1 identified by similarity to SP:P0AED9; match to protein family HMM PF00145; match to protein family HMM TIGR00675 YP_001463263.1 identified by match to protein family HMM PF01966 YP_001463265.1 identified by glimmer YP_001463266.1 identified by match to protein family HMM PF00267; match to protein family HMM TIGR03304 YP_001463267.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress YP_001463268.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR01386 YP_001463269.1 induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced YP_001463270.1 identified by match to protein family HMM PF00576; match to protein family HMM TIGR02962 YP_001463271.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001463272.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_001463273.1 identified by similarity to SP:P76344; match to protein family HMM PF09223 YP_001463274.1 identified by match to protein family HMM PF01292 YP_001463275.1 identified by glimmer YP_001463276.1 identified by similarity to SP:P03764; match to protein family HMM PF08400 YP_001463277.1 identified by glimmer YP_001463279.1 identified by similarity to GB:AAG04013.1 YP_001463281.1 identified by similarity to SP:P22501; match to protein family HMM PF04984 YP_001463282.1 identified by glimmer YP_001463283.1 identified by match to protein family HMM TIGR01634 YP_001463284.1 identified by similarity to SP:P51767; match to protein family HMM PF04865 YP_001463285.1 identified by similarity to SP:P51768; match to protein family HMM PF04965 YP_001463286.1 identified by similarity to SP:P31340; match to protein family HMM PF04717; match to protein family HMM TIGR01644 YP_001463287.1 identified by glimmer YP_001463288.1 identified by glimmer YP_001463289.1 identified by glimmer YP_001463290.1 identified by similarity to GB:AAC19046.1 YP_001463291.1 identified by match to protein family HMM PF03864 YP_001463292.1 identified by match to protein family HMM PF02924 YP_001463293.1 identified by match to protein family HMM PF01343 YP_001463294.1 identified by match to protein family HMM PF00308; match to protein family HMM PF01695 YP_001463295.1 identified by similarity to SP:P15025; match to protein family HMM PF00665 YP_001463296.1 identified by match to protein family HMM PF05876 YP_001463297.1 identified by glimmer YP_001463298.1 identified by match to protein family HMM TIGR02594 YP_001463299.1 identified by match to protein family HMM PF06323 YP_001463300.1 identified by match to protein family HMM PF07102 YP_001463301.1 identified by similarity to GB:AAX66528.1; match to protein family HMM PF07105 YP_001463302.1 identified by glimmer YP_001463303.1 identified by glimmer YP_001463304.1 identified by glimmer YP_001463305.1 identified by similarity to GB:AAX67604.1 YP_001463306.1 identified by glimmer YP_001463307.1 identified by glimmer YP_001463311.1 identified by glimmer YP_001463312.1 identified by glimmer YP_001463313.1 identified by similarity to GB:AAT84997.1 YP_001463314.1 identified by match to protein family HMM PF03796 YP_001463316.1 identified by similarity to GB:CAE15847.1 YP_001463317.1 identified by similarity to GB:CAE15848.1; match to protein family HMM PF06254 YP_001463318.1 The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown. YP_001463319.1 identified by glimmer YP_001463320.1 identified by similarity to GB:CAE15856.1 YP_001463321.1 identified by glimmer YP_001463322.1 identified by similarity to GB:AAN69513.1 YP_001463323.1 identified by match to protein family HMM PF00589 YP_001463324.1 identified by similarity to SP:P76346; match to protein family HMM PF06167 YP_001463325.1 identified by similarity to SP:P11922; match to protein family HMM PF00801; match to protein family HMM PF02369 YP_001463327.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_001463328.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_001463329.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033 YP_001463330.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_001463331.1 LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB YP_001463332.1 Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation YP_001463333.1 identified by match to protein family HMM PF03734 YP_001463334.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_001463335.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole YP_001463336.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP YP_001463337.1 identified by similarity to SP:Q05631 YP_001463338.1 identified by similarity to SP:Q05587; match to protein family HMM PF00165 YP_001463339.1 identified by similarity to SP:P37451; match to protein family HMM PF00230; match to protein family HMM TIGR00861 YP_001463340.1 identified by similarity to SP:P0A1C7; match to protein family HMM PF00936 YP_001463341.1 identified by similarity to SP:P37449; match to protein family HMM PF00936 YP_001463342.1 identified by similarity to SP:P37450; match to protein family HMM PF02286 YP_001463343.1 identified by similarity to GB:AAB84103.1; match to protein family HMM PF02288 YP_001463344.1 identified by similarity to GB:AAB84104.1; match to protein family HMM PF02287 YP_001463345.1 identified by similarity to GB:AAB84105.2; match to protein family HMM PF08841 YP_001463346.1 identified by similarity to GB:AAD39009.1; match to protein family HMM PF00936 YP_001463347.1 identified by similarity to GB:AAD39010.1; match to protein family HMM PF00936 YP_001463348.1 identified by match to protein family HMM PF06130 YP_001463349.1 identified by similarity to GB:AAD39012.1 YP_001463350.1 identified by similarity to GB:AAD39013.1; match to protein family HMM PF03319 YP_001463351.1 identified by similarity to GB:AAD39014.1; match to protein family HMM PF01923; match to protein family HMM PF03928; match to protein family HMM TIGR00636 YP_001463352.1 identified by similarity to GB:AAD39015.1; match to protein family HMM PF00171 YP_001463353.1 identified by similarity to GB:AAD39016.1; match to protein family HMM PF00465 YP_001463354.1 identified by similarity to GB:AAD39017.1; match to protein family HMM PF00037; match to protein family HMM PF01512 YP_001463355.1 identified by similarity to GB:AAV76807.1; match to protein family HMM PF00936 YP_001463356.1 identified by similarity to SP:P0A1D1; match to protein family HMM PF00936 YP_001463357.1 identified by similarity to SP:Q9XDM6; match to protein family HMM TIGR02528 YP_001463358.1 identified by match to protein family HMM PF04363 YP_001463360.1 identified by similarity to GB:1JYH_A; match to protein family HMM PF06445 YP_001463361.1 removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_001463362.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_001463363.1 identified by match to protein family HMM PF01206 YP_001463364.1 identified by match to protein family HMM PF04143 YP_001463365.1 identified by match to protein family HMM PF00324 YP_001463366.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001463367.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370 YP_001463368.1 identified by similarity to SP:P69349; match to protein family HMM PF06769; match to protein family HMM TIGR02116 YP_001463369.1 Antitoxin that counteracts the effect of the YoeB toxin YP_001463370.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_001463371.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001463372.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001463373.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_001463374.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001463375.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001463376.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001463377.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_001463378.1 identified by similarity to SP:P76372; match to protein family HMM PF02706 YP_001463379.1 identified by match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026 YP_001463380.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_001463383.1 identified by glimmer YP_001463384.1 identified by similarity to SP:Q04973; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993 YP_001463385.1 identified by similarity to SP:Q04972; match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026 YP_001463388.1 identified by match to protein family HMM PF00535 YP_001463389.1 identified by match to protein family HMM PF00908; match to protein family HMM TIGR01221 YP_001463390.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207 YP_001463391.1 with dTDP-4-dehydrorhamnose 3,5-epimerase forms a complex known as dTDP-L-rhamnose synthetase; catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose YP_001463392.1 NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose YP_001463393.1 identified by glimmer YP_001463394.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_001463395.1 WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid YP_001463396.1 identified by match to protein family HMM PF00534 YP_001463397.1 identified by match to protein family HMM PF04230 YP_001463398.1 identified by match to protein family HMM PF01943 YP_001463399.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid YP_001463400.1 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880 YP_001463401.1 identified by similarity to GB:AAN81029.1 YP_001463402.1 identified by similarity to SP:P24174; match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479 YP_001463403.1 identified by match to protein family HMM PF00534 YP_001463404.1 identified by similarity to SP:P32056; match to protein family HMM PF00293 YP_001463405.1 identified by match to protein family HMM PF01370; match to protein family HMM PF04321 YP_001463406.1 identified by match to protein family HMM PF01370; match to protein family HMM TIGR01472 YP_001463407.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit) YP_001463408.1 identified by match to protein family HMM PF00535 YP_001463409.1 essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance YP_001463411.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium YP_001463412.1 identified by match to protein family HMM PF00535 YP_001463413.1 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide) YP_001463414.1 Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis YP_001463415.1 identified by match to protein family HMM PF02563 YP_001463416.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471; match to protein family HMM PF03741 YP_001463417.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs YP_001463418.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_001463419.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_001463420.1 contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction YP_001463421.1 inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine YP_001463424.1 identified by similarity to GB:AAP17498.1 YP_001463425.1 identified by match to protein family HMM PF00092 YP_001463426.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_001463427.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_001463428.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate YP_001463429.1 identified by match to protein family HMM PF07690 YP_001463430.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_001463431.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport YP_001463432.1 identified by similarity to SP:Q8EAL4; similarity to GB:CAG67631.1; match to protein family HMM PF07411 YP_001463433.1 identified by match to protein family HMM PF01402; match to protein family HMM PF03693; match to protein family HMM TIGR02606 YP_001463434.1 identified by match to protein family HMM PF05016 YP_001463435.1 identified by match to protein family HMM PF01136 YP_001463436.1 identified by similarity to GB:ABB65576.1 YP_001463437.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role YP_001463438.1 identified by similarity to SP:P36930; match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_001463439.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate YP_001463440.1 identified by match to protein family HMM PF03611; match to protein family HMM TIGR00827 YP_001463441.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001463442.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001463443.1 identified by match to protein family HMM PF08013; match to protein family HMM TIGR02810 YP_001463444.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway YP_001463445.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate YP_001463446.1 identified by match to protein family HMM PF03825; match to protein family HMM PF07690; match to protein family HMM TIGR00889 YP_001463447.1 identified by match to protein family HMM PF03747 YP_001463448.1 identified by match to protein family HMM PF00294 YP_001463449.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM PF08279 YP_001463450.1 identified by match to protein family HMM PF01183 YP_001463451.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_001463452.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_001463453.1 identified by similarity to SP:P64530; match to protein family HMM PF02583 YP_001463454.1 identified by similarity to GB:AAN81090.1 YP_001463456.1 identified by glimmer YP_001463457.1 identified by match to protein family HMM PF00577 YP_001463458.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001463459.1 identified by glimmer YP_001463460.1 identified by match to protein family HMM PF00419 YP_001463461.1 identified by similarity to SP:P0AF08 YP_001463462.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001463463.1 identified by similarity to SP:P33345; match to protein family HMM PF05406 YP_001463464.1 identified by match to protein family HMM PF07728 YP_001463465.1 identified by similarity to GB:AAN81106.1 YP_001463466.1 yehP; identified by match to protein family HMM PF05762 YP_001463467.1 identified by match to protein family HMM PF04434 YP_001463468.1 identified by match to protein family HMM PF06998 YP_001463469.1 identified by match to protein family HMM PF07308 YP_001463470.1 unknown function; when overproduced it confers drug-resistance YP_001463471.1 identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694 YP_001463472.1 identified by similarity to SP:P33358; match to protein family HMM PF00376 YP_001463473.1 identified by similarity to GB:AAZ88835.1 YP_001463474.1 identified by match to protein family HMM PF00528 YP_001463475.1 identified by match to protein family HMM PF00005 YP_001463476.1 identified by match to protein family HMM PF00528 YP_001463477.1 identified by match to protein family HMM PF04069 YP_001463478.1 identified by similarity to SP:P33363; match to protein family HMM PF00933; match to protein family HMM PF01915 YP_001463479.1 identified by glimmer YP_001463480.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent YP_001463481.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_001463482.1 identified by match to protein family HMM PF06930 YP_001463483.1 identified by similarity to SP:P33366; match to protein family HMM PF09335 YP_001463484.1 identified by match to protein family HMM PF00106 YP_001463485.1 may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_001463486.1 identified by similarity to SP:P33371; match to protein family HMM PF01207 YP_001463487.1 identified by match to protein family HMM PF02798; match to protein family HMM TIGR01262 YP_001463488.1 identified by match to protein family HMM PF01557 YP_001463489.1 identified by similarity to GB:CAA12267.1; match to protein family HMM PF07883; match to protein family HMM TIGR02272 YP_001463490.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_001463491.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001463492.1 identified by match to protein family HMM PF03788 YP_001463493.1 identified by match to protein family HMM PF04172; match to protein family HMM TIGR00659 YP_001463494.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_001463495.1 identified by similarity to SP:P0AFY5; match to protein family HMM PF02698 YP_001463496.1 identified by similarity to SP:P64539 YP_001463497.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_001463498.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines YP_001463499.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex YP_001463500.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains YP_001463501.1 identified by similarity to SP:P0AEE5; match to protein family HMM PF00532 YP_001463502.1 negative regulator of the mglBAC operon for galactose utilization YP_001463503.1 identified by glimmer YP_001463504.1 identified by match to protein family HMM PF04171; match to protein family HMM PF04235 YP_001463505.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001463506.1 identified by match to protein family HMM PF00756; match to protein family HMM TIGR02821 YP_001463507.1 Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein YP_001463508.1 identified by glimmer YP_001463509.1 identified by match to protein family HMM PF00324 YP_001463510.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001463511.1 identified by match to protein family HMM PF03601; match to protein family HMM TIGR00698 YP_001463512.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_001463513.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804 YP_001463514.1 Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively YP_001463515.1 activator of nucleoside metabolism YP_001463516.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804 YP_001463517.1 identified by match to protein family HMM PF04227 YP_001463518.1 identified by match to protein family HMM PF00294 YP_001463519.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001463520.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers YP_001463521.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr YP_001463522.1 identified by glimmer YP_001463523.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00899 YP_001463524.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein YP_001463525.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_001463526.1 identified by match to protein family HMM PF02492; match to protein family HMM PF07683 YP_001463527.1 identified by match to protein family HMM PF01569 YP_001463528.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance YP_001463529.1 identified by similarity to SP:P76446; match to protein family HMM PF00563 YP_001463530.1 identified by match to protein family HMM PF00496 YP_001463531.1 identified by match to protein family HMM PF00528 YP_001463532.1 identified by match to protein family HMM PF00528 YP_001463533.1 identified by match to protein family HMM PF00005 YP_001463534.1 identified by similarity to SP:P0AD23 YP_001463535.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance YP_001463536.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA YP_001463537.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851 YP_001463538.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001463539.1 identified by similarity to SP:P33920; match to protein family HMM PF04245 YP_001463540.1 identified by glimmer YP_001463541.1 identified by match to protein family HMM PF07208 YP_001463542.1 identified by match to protein family HMM PF00884 YP_001463543.1 identified by glimmer YP_001463544.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes YP_001463545.1 identified by match to protein family HMM PF03918 YP_001463546.1 identified by similarity to SP:P0AA86; match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR00385 YP_001463547.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR00353 YP_001463548.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_001463549.1 identified by match to protein family HMM PF04995; match to protein family HMM TIGR03141 YP_001463550.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR01191 YP_001463551.1 identified by match to protein family HMM PF03379; match to protein family HMM TIGR01190 YP_001463552.1 ATP-binding protein; required for proper cytochrome c maturation YP_001463553.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone YP_001463554.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA YP_001463555.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA YP_001463556.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway YP_001463557.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_001463558.1 identified by match to protein family HMM PF03927 YP_001463559.1 Predicted role in electron transfer to the periplasmic nitrate reductase NapA. YP_001463560.1 serine protease inhibitor, inhibits trypsin and other proteases YP_001463561.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_001463562.1 efflux pump for the antibacterial peptide microcin J25 YP_001463563.1 identified by similarity to SP:P05050; match to protein family HMM PF03171; match to protein family HMM TIGR00568 YP_001463564.1 identified by similarity to SP:P06134; match to protein family HMM PF00165; match to protein family HMM PF01035; match to protein family HMM PF02805; match to protein family HMM PF02870; match to protein family HMM TIGR00589 YP_001463565.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway YP_001463566.1 allows for ions and hydrophilic solutes to cross the outer membrane YP_001463567.1 identified by match to protein family HMM PF01627; match to protein family HMM PF02518 YP_001463568.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF YP_001463569.1 identified by glimmer YP_001463570.1 identified by glimmer YP_001463571.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518 YP_001463572.1 identified by glimmer YP_001463573.1 identified by similarity to GB:AAG07875.1 YP_001463574.1 identified by similarity to GB:AAZ88932.1 YP_001463575.1 identified by match to protein family HMM PF01835; match to protein family HMM PF07703 YP_001463576.2 identified by match to protein family HMM PF06672 YP_001463577.1 identified by similarity to SP:P17994 YP_001463578.1 negatively supercoils closed circular double-stranded DNA YP_001463579.1 Involved in ubiquinone biosynthesis YP_001463580.1 yfaL; identified by match to protein family HMM PF02415; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01376; match to protein family HMM TIGR01414; match to protein family HMM TIGR02601 YP_001463581.1 identified by glimmer YP_001463582.1 identified by glimmer YP_001463583.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001463584.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_001463585.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases YP_001463586.1 identified by match to protein family HMM PF06293 YP_001463588.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic YP_001463589.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell YP_001463590.1 identified by glimmer YP_001463591.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor YP_001463592.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters YP_001463593.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate YP_001463594.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_001463595.1 identified by match to protein family HMM PF03328 YP_001463596.1 identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; match to protein family HMM TIGR00200 YP_001463597.1 identified by similarity to SP:P76471; match to protein family HMM PF07437 YP_001463598.1 identified by match to protein family HMM PF00293 YP_001463599.1 identified by match to protein family HMM PF00300 YP_001463600.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose YP_001463601.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate YP_001463602.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains YP_001463603.1 identified by match to protein family HMM PF01522 YP_001463604.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A YP_001463605.1 identified by match to protein family HMM PF00893 YP_001463607.1 identified by similarity to SP:P37590 YP_001463608.1 identified by match to protein family HMM PF00501; match to protein family HMM TIGR01923 YP_001463609.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_001463610.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_001463611.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA YP_001463612.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_001463613.1 identified by similarity to SP:P38051; match to protein family HMM PF00425; match to protein family HMM TIGR00543 YP_001463614.1 elaB; identified by similarity to GB:CAG75914.1; match to protein family HMM PF05957 YP_001463615.1 identified by match to protein family HMM PF00583 YP_001463616.1 member of metallo-beta-lactamase; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_001463617.1 ElaD; specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins; SseL in Salmonella is required for macrophage killing and virulence, and it is secreted by the salmonella pathogenicity island 2 type III secretion system YP_001463618.1 identified by similarity to GB:BAB36582.1; match to protein family HMM PF08974 YP_001463619.1 Catalyzes the transfer of electrons from NADH to quinone YP_001463620.1 Catalyzes the transfer of electrons from NADH to quinone YP_001463621.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001463622.1 Catalyzes the transfer of electrons from NADH to quinone YP_001463623.1 Catalyzes the transfer of electrons from NADH to quinone YP_001463624.1 Catalyzes the transfer of electrons from NADH to quinone YP_001463625.1 Catalyzes the transfer of electrons from NADH to quinone YP_001463626.1 Catalyzes the transfer of electrons from NADH to quinone YP_001463627.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_001463628.1 Catalyzes the transfer of electrons from NADH to quinone YP_001463629.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms YP_001463630.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001463631.1 Catalyzes the transfer of electrons from NADH to quinone YP_001463632.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001463633.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_001463634.1 identified by similarity to SP:P76491; match to protein family HMM PF01966 YP_001463635.1 identified by match to protein family HMM PF02080; match to protein family HMM PF03600; match to protein family HMM PF06808 YP_001463636.1 identified by similarity to SP:P77625; match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549 YP_001463637.1 identified by match to protein family HMM PF03887 YP_001463638.1 identified by match to protein family HMM PF04217 YP_001463639.1 identified by similarity to GB:AAN81291.1 YP_001463640.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_001463641.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_001463642.1 identified by match to protein family HMM PF03606 YP_001463643.1 identified by match to protein family HMM PF00293 YP_001463644.1 identified by similarity to SP:P67095; match to protein family HMM PF00149; match to protein family HMM TIGR00040 YP_001463645.1 identified by match to protein family HMM PF02798 YP_001463646.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_001463647.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate YP_001463648.1 identified by match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM PF08338; match to protein family HMM TIGR01777 YP_001463649.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_001463650.1 identified by match to protein family HMM PF00005 YP_001463651.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001463652.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001463653.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_001463654.1 identified by similarity to SP:P09551; match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_001463655.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate YP_001463656.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001463657.1 membrane protein required for colicin V production YP_001463658.1 identified by match to protein family HMM PF05036 YP_001463659.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499 YP_001463660.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_001463661.1 identified by match to protein family HMM PF09335 YP_001463662.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001463663.1 identified by similarity to SP:P08390; match to protein family HMM PF01118; match to protein family HMM PF02774 YP_001463664.1 identified by glimmer YP_001463665.1 identified by similarity to SP:P05459; match to protein family HMM PF00389; match to protein family HMM PF02826 YP_001463666.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein YP_001463667.1 identified by match to protein family HMM PF07690 YP_001463668.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001463669.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_001463670.1 identified by similarity to GB:ABB66925.1; match to protein family HMM PF08891 YP_001463671.1 identified by match to protein family HMM PF04315 YP_001463672.1 identified by match to protein family HMM PF01925 YP_001463673.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_001463674.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001463675.1 involved in methylation of ribosomal protein L3 YP_001463676.1 identified by match to protein family HMM PF01713 YP_001463677.1 identified by similarity to GB:ABB66932.1 YP_001463678.1 identified by match to protein family HMM PF00419 YP_001463680.1 identified by similarity to GB:AAV76235.1 YP_001463681.1 identified by match to protein family HMM PF00345 YP_001463682.1 identified by glimmer YP_001463683.1 identified by match to protein family HMM PF00577 YP_001463684.1 identified by glimmer YP_001463685.1 identified by similarity to GB:AAC64152.1; match to protein family HMM PF00419 YP_001463686.1 identified by match to protein family HMM PF00300; match to protein family HMM TIGR00249 YP_001463687.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate YP_001463688.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_001463689.1 identified by match to protein family HMM PF04175; match to protein family HMM TIGR00743 YP_001463690.1 identified by match to protein family HMM PF03349 YP_001463691.1 identified by similarity to GB:AAP17747.1 YP_001463692.1 identified by match to protein family HMM PF04333 YP_001463693.1 identified by similarity to GB:AAN81341.1 YP_001463695.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments YP_001463696.1 phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least YP_001463697.1 identified by glimmer YP_001463698.1 identified by match to protein family HMM PF00251; match to protein family HMM PF08244; match to protein family HMM TIGR01322 YP_001463699.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001463700.1 identified by glimmer YP_001463701.1 catalyzes the formation of pyruvate from serine YP_001463702.1 identified by similarity to SP:P52600; match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_001463703.1 identified by similarity to SP:P52599; match to protein family HMM PF00529; match to protein family HMM TIGR00998 YP_001463704.1 response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance YP_001463705.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00497; match to protein family HMM PF00512; match to protein family HMM PF01627; match to protein family HMM PF02518 YP_001463706.1 identified by glimmer YP_001463707.1 identified by match to protein family HMM PF02515 YP_001463708.1 identified by glimmer YP_001463709.1 member of the AEC family of auxin efflux transporters; unknown function YP_001463710.1 catalyzes the formation of formyl-CoA from oxalyl-CoA YP_001463711.1 catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA YP_001463712.1 identified by similarity to GB:AAZ89107.1 YP_001463713.1 identified by glimmer YP_001463714.1 identified by similarity to GB:AAZ89109.1 YP_001463715.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock YP_001463716.1 identified by glimmer YP_001463717.1 identified by match to protein family HMM PF00155 YP_001463718.1 identified by glimmer YP_001463719.1 identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694 YP_001463720.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397 YP_001463721.1 identified by match to protein family HMM PF00165 YP_001463722.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR00848; match to protein family HMM TIGR01417 YP_001463723.1 metalloprotein YP_001463724.1 Xaa-Pro aminopeptidase; limited methionine aminopeptidase YP_001463725.1 identified by similarity to SP:Q8XBP8; match to protein family HMM PF02378; match to protein family HMM TIGR01427 YP_001463726.1 identified by match to protein family HMM PF02379; match to protein family HMM TIGR00829 YP_001463727.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_001463729.1 identified by glimmer YP_001463730.1 identified by similarity to SP:P64544 YP_001463731.1 identified by match to protein family HMM PF01566; match to protein family HMM TIGR01197 YP_001463732.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804 YP_001463733.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM PF05231 YP_001463735.1 identified by match to protein family HMM PF07037 YP_001463736.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001463737.1 identified by similarity to GB:AAP17783.1 YP_001463738.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001463739.1 identified by match to protein family HMM PF01758 YP_001463740.1 identified by similarity to SP:P0AD40 YP_001463741.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_001463742.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure YP_001463743.1 role in sulfur assimilation YP_001463744.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_001463745.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_001463746.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system YP_001463747.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_001463748.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_001463749.1 identified by similarity to GB:ABB66999.1 YP_001463750.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide YP_001463751.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR00968 YP_001463752.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import YP_001463753.1 identified by similarity to SP:P16701; match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02139 YP_001463754.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971 YP_001463755.1 identified by similarity to SP:P37440; match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659 YP_001463756.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_001463757.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_001463758.1 belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component YP_001463759.1 identified by match to protein family HMM PF00144 YP_001463760.1 identified by match to protein family HMM PF04261; match to protein family HMM TIGR01413 YP_001463761.1 identified by match to protein family HMM PF06572 YP_001463763.1 identified by match to protein family HMM PF00583 YP_001463764.1 identified by similarity to SP:P36548; match to protein family HMM PF01520; match to protein family HMM TIGR01409 YP_001463765.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001463766.1 activates the transcription of the ethanolamine utilization operon YP_001463767.1 identified by similarity to SP:Q9ZFU8; match to protein family HMM PF00936 YP_001463768.1 identified by similarity to SP:P0A1C9; match to protein family HMM PF00936 YP_001463769.1 catalyzes the formation of acetaldehyde from ethanolamine YP_001463770.1 identified by similarity to SP:P19264; match to protein family HMM PF06751 YP_001463771.1 ethanolamine utilization protein EutA YP_001463772.1 identified by similarity to SP:P41796; match to protein family HMM PF04346 YP_001463773.1 identified by similarity to SP:P41795; match to protein family HMM PF00465 YP_001463774.1 identified by similarity to SP:P0A206; match to protein family HMM TIGR02529 YP_001463775.1 identified by similarity to SP:P41793; match to protein family HMM PF00171 YP_001463776.1 identified by similarity to SP:P41792; match to protein family HMM PF03319 YP_001463777.1 identified by match to protein family HMM PF00936 YP_001463778.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta YP_001463779.1 identified by similarity to SP:Q9ZFV4; match to protein family HMM PF01923 YP_001463780.1 identified by match to protein family HMM PF05899; match to protein family HMM PF06249 YP_001463781.1 identified by similarity to SP:P0A208; match to protein family HMM TIGR02528 YP_001463782.1 identified by similarity to SP:Q9ZFV7; match to protein family HMM PF00936 YP_001463783.1 identified by glimmer YP_001463784.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_001463785.1 identified by match to protein family HMM PF00923; match to protein family HMM TIGR00874 YP_001463786.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001463787.1 identified by glimmer YP_001463788.1 identified by similarity to GB:ABB67033.1; match to protein family HMM PF06674 YP_001463789.1 identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052 YP_001463790.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) YP_001463791.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF07730 YP_001463792.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_001463793.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617 YP_001463794.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001463795.1 identified by similarity to GB:AAN81450.1 YP_001463796.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_001463797.1 identified by similarity to GB:ABB62712.1; match to protein family HMM PF05127 YP_001463798.1 identified by match to protein family HMM PF04228 YP_001463799.1 identified by similarity to GB:AAL23544.1 YP_001463800.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001463801.1 identified by glimmer YP_001463802.1 identified by match to protein family HMM PF06804 YP_001463803.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001463804.1 negative transcriptional regulator of the gcvTHP operon YP_001463805.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_001463806.1 identified by match to protein family HMM PF00037 YP_001463807.1 identified by similarity to SP:P16430; similarity to SP:P77858; match to protein family HMM PF00146 YP_001463808.1 interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide YP_001463809.1 identified by similarity to SP:P77329; match to protein family HMM PF00329; match to protein family HMM PF00346 YP_001463810.1 probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far YP_001463811.1 identified by similarity to SP:P77668; match to protein family HMM PF01058 YP_001463812.1 identified by match to protein family HMM PF07450 YP_001463813.1 identified by similarity to SP:P19323; match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954 YP_001463814.1 inner membrane protein presumed to act as a formate transporter; member of the hyf operon YP_001463815.1 identified by match to protein family HMM PF01594 YP_001463816.1 identified by match to protein family HMM PF01435 YP_001463817.1 identified by glimmer YP_001463818.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_001463819.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801 YP_001463820.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_001463821.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001463822.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_001463823.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_001463824.1 identified by match to protein family HMM PF02541 YP_001463825.1 identified by match to protein family HMM PF00563; match to protein family HMM PF05231 YP_001463826.1 identified by similarity to GB:AAG57614.1 YP_001463827.1 identified by similarity to GB:AAL21400.1 YP_001463828.1 identified by match to protein family HMM PF05433 YP_001463829.1 identified by similarity to SP:P76573 YP_001463830.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001463831.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001463832.1 identified by similarity to GB:AAZ89220.1; match to protein family HMM PF07191 YP_001463833.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001463834.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_001463835.1 identified by similarity to GB:AAP83327.1 YP_001463836.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001463837.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001463838.1 identified by match to protein family HMM PF01381 YP_001463839.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_001463840.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001463841.1 penicillin-insensitive transglycosylase/transpeptidase YP_001463842.1 identified by match to protein family HMM PF01835; match to protein family HMM PF07703 YP_001463843.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds YP_001463844.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I YP_001463845.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_001463846.1 identified by similarity to SP:P0C0L9; match to protein family HMM PF04384; match to protein family HMM TIGR03412 YP_001463847.1 identified by match to protein family HMM PF00111; match to protein family HMM TIGR02007 YP_001463848.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_001463849.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_001463850.1 identified by glimmer YP_001463851.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein YP_001463852.1 identified by match to protein family HMM PF01592; match to protein family HMM TIGR01999 YP_001463853.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_001463854.1 regulates the expression of the iscRSUA operon YP_001463855.1 identified by match to protein family HMM PF00588; match to protein family HMM TIGR00050 YP_001463856.1 identified by similarity to SP:P0ADG4; match to protein family HMM PF00459 YP_001463858.1 identified by match to protein family HMM PF00874 YP_001463859.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters YP_001463860.1 activator of 3-phenylpropionic acid catabolism YP_001463861.1 identified by similarity to SP:Q47140; match to protein family HMM PF00866 YP_001463862.1 identified by similarity to SP:P0ABW2; match to protein family HMM PF00355 YP_001463863.1 Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate YP_001463864.1 identified by similarity to SP:P77650; match to protein family HMM PF00070; match to protein family HMM PF07992 YP_001463865.1 identified by match to protein family HMM PF07681 YP_001463866.1 identified by match to protein family HMM PF01263 YP_001463867.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001463868.1 identified by match to protein family HMM PF02653 YP_001463869.1 yphE; identified by match to protein family HMM PF00005 YP_001463870.1 identified by match to protein family HMM PF00532 YP_001463871.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719 YP_001463872.1 identified by match to protein family HMM PF00480 YP_001463873.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001463874.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_001463875.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA YP_001463876.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF07728 YP_001463878.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_001463879.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001463880.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_001463881.1 identified by similarity to SP:P68398; match to protein family HMM PF00383 YP_001463882.1 identified by match to protein family HMM TIGR01545 YP_001463883.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_001463884.1 identified by match to protein family HMM PF00037 YP_001463885.1 identified by glimmer YP_001463886.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001463887.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001463888.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_001463889.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001463890.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001463891.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins YP_001463892.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001463893.1 involved in the reduction of the SoxR iron-sulfur cluster YP_001463894.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP YP_001463895.1 identified by match to protein family HMM PF03872; match to protein family HMM PF03873 YP_001463896.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_001463897.1 identified by glimmer YP_001463898.1 catalyzes the formation of oxaloacetate from L-aspartate YP_001463899.1 identified by match to protein family HMM PF05175 YP_001463900.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_001463901.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001463902.1 identified by match to protein family HMM PF01810 YP_001463903.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit YP_001463904.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_001463905.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032 YP_001463906.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068 YP_001463907.1 identified by match to protein family HMM PF03942 YP_001463908.1 identified by similarity to GB:BAA07751.1; match to protein family HMM PF00583; match to protein family HMM PF02629 YP_001463909.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_001463911.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_001463912.1 identified by similarity to GB:AAN81562.1 YP_001463913.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728 YP_001463914.1 identified by similarity to PDB:1XAF_A; match to protein family HMM PF02578; match to protein family HMM TIGR00726 YP_001463915.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA YP_001463916.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline YP_001463917.1 associated with 30S ribosomal subunit; interferes with translation elongation YP_001463918.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_001463919.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_001463920.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_001463922.1 identified by similarity to SP:P64548 YP_001463923.1 identified by match to protein family HMM PF00672; match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001463924.1 identified by match to protein family HMM PF00691 YP_001463925.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001463926.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001463927.1 Essential for efficient processing of 16S rRNA YP_001463928.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001463929.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_001463930.1 identified by match to protein family HMM PF01578 YP_001463931.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_001463932.1 identified by similarity to GB:AAX66587.1 YP_001463933.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001463934.1 catalyzes the phosphorylation of NAD to NADP YP_001463935.1 identified by similarity to SP:P05824; match to protein family HMM PF02463; match to protein family HMM TIGR00634 YP_001463936.1 identified by match to protein family HMM PF04355 YP_001463937.1 identified by similarity to SP:P52119; match to protein family HMM PF03658 YP_001463938.1 identified by match to protein family HMM PF03364 YP_001463939.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001463940.1 identified by match to protein family HMM PF00589 YP_001463941.1 identified by match to protein family HMM PF00239; match to protein family HMM PF07508 YP_001463942.1 identified by match to protein family HMM PF02195 YP_001463943.1 identified by match to protein family HMM PF07506 YP_001463944.1 identified by match to protein family HMM PF02384 YP_001463945.1 identified by match to protein family HMM PF01420 YP_001463946.1 identified by match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM TIGR00348 YP_001463947.1 identified by similarity to GB:AAO54619.1 YP_001463948.1 identified by glimmer YP_001463949.1 identified by glimmer YP_001463950.1 identified by glimmer YP_001463951.1 identified by glimmer YP_001463952.1 identified by similarity to GB:CAG73977.1 YP_001463953.1 identified by match to protein family HMM PF03432 YP_001463956.1 identified by similarity to SP:P15025; match to protein family HMM PF00665 YP_001463957.1 identified by match to protein family HMM PF00308; match to protein family HMM PF01695 YP_001463958.1 identified by similarity to GB:CAG73974.1 YP_001463959.1 identified by similarity to GB:AAS55464.1 YP_001463961.1 identified by glimmer YP_001463962.1 identified by glimmer YP_001463963.1 identified by similarity to GB:CAG74503.1 YP_001463964.1 identified by glimmer YP_001463965.1 identified by match to protein family HMM PF01527 YP_001463966.1 identified by match to protein family HMM PF05717 YP_001463967.1 identified by match to protein family HMM PF00128 YP_001463968.1 identified by similarity to GB:AAP18006.1 YP_001463969.1 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution YP_001463970.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate YP_001463971.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent YP_001463972.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_001463973.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR01773 YP_001463974.1 regulator of gab gene expression YP_001463975.1 identified by match to protein family HMM PF01476; match to protein family HMM PF04972 YP_001463976.1 identified by similarity to GB:AAV78517.1; match to protein family HMM PF01679 YP_001463977.1 identified by match to protein family HMM PF01022 YP_001463978.1 identified by similarity to SP:P55734 YP_001463979.1 identified by similarity to SP:P0ACG3; match to protein family HMM PF00816 YP_001463980.1 identified by glimmer YP_001463981.1 identified by similarity to SP:P64553; match to protein family HMM PF06610 YP_001463983.1 identified by similarity to GB:AAL21687.1; match to protein family HMM PF05957 YP_001463984.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_001463985.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001463986.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_001463987.1 with ProWX is involved in the high-affinity uptake of glycine betaine YP_001463988.1 with ProVX is involved in the high-affinity uptake of glycine betaine YP_001463989.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine YP_001463990.1 identified by glimmer YP_001463991.1 identified by glimmer YP_001463992.1 identified by glimmer YP_001463993.1 identified by match to protein family HMM PF07690 YP_001463994.1 identified by match to protein family HMM PF03591 YP_001463995.1 identified by similarity to GB:AAZ89437.1 YP_001463996.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB YP_001463997.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR00998 YP_001463998.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_001463999.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_001464000.1 involved in the first step of glutathione biosynthesis YP_001464002.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent YP_001464003.1 affects carbohydrate metabolism; has regulatory role in many processes YP_001464004.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001464005.1 identified by glimmer YP_001464006.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_001464007.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001464008.1 identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199 YP_001464009.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan YP_001464010.1 identified by match to protein family HMM PF03608; match to protein family HMM TIGR00821 YP_001464011.1 identified by match to protein family HMM PF03612; match to protein family HMM PF07663; match to protein family HMM TIGR00825 YP_001464012.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001464013.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate YP_001464014.1 regulator for glucitol utilization YP_001464015.1 regulates genes involved in glucitol utilization YP_001464016.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate YP_001464017.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_001464018.1 detoxifies nitric oxide using NADH YP_001464019.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase YP_001464020.1 identified by match to protein family HMM PF00708; match to protein family HMM PF01300; match to protein family HMM PF07503; match to protein family HMM TIGR00143 YP_001464021.1 involved in electron transport from formate to hydrogen YP_001464022.1 identified by glimmer YP_001464023.1 identified by similarity to SP:P24242; match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001464024.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001464025.1 identified by similarity to SP:P24240; match to protein family HMM PF00232 YP_001464026.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001464027.1 identified by match to protein family HMM PF01381 YP_001464028.1 identified by similarity to GB:AAZ89467.1 YP_001464029.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE YP_001464030.1 identified by match to protein family HMM PF07450 YP_001464031.1 identified by similarity to SP:P16433; match to protein family HMM PF01058 YP_001464032.1 electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate YP_001464033.1 identified by similarity to SP:P16431; match to protein family HMM PF00329; match to protein family HMM PF00346 YP_001464034.1 identified by similarity to SP:P16430; match to protein family HMM PF00146 YP_001464035.1 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3) YP_001464036.1 identified by similarity to SP:P0AAK1; match to protein family HMM PF00037 YP_001464037.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon YP_001464038.1 plays a role in hydrogenase nickel cofactor insertion YP_001464039.1 GTP hydrolase involved in nickel liganding into hydrogenases YP_001464040.1 HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase YP_001464041.1 identified by similarity to SP:P24192; match to protein family HMM PF01924; match to protein family HMM TIGR00075 YP_001464042.1 identified by similarity to SP:P24193; match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR02124 YP_001464043.1 identified by similarity to SP:P19323; match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; match to protein family HMM PF07728 YP_001464044.1 identified by similarity to SP:P25728 YP_001464045.1 identified by glimmer YP_001464046.1 identified by glimmer YP_001464047.1 identified by glimmer YP_001464048.1 identified by match to protein family HMM PF01527 YP_001464049.1 identified by similarity to SP:P05822; match to protein family HMM PF00665 YP_001464051.1 identified by match to protein family HMM PF00589 YP_001464052.1 This protein performs the mismatch recognition step during the DNA repair process YP_001464053.1 identified by match to protein family HMM PF00149 YP_001464054.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_001464055.1 identified by match to protein family HMM PF03446 YP_001464056.1 identified by match to protein family HMM PF07005 YP_001464057.1 identified by match to protein family HMM PF00596 YP_001464058.1 identified by match to protein family HMM PF01261 YP_001464059.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function YP_001464060.1 identified by similarity to GB:AAY57856.1 YP_001464061.1 identified by similarity to GB:AAY57855.1; match to protein family HMM PF01977; match to protein family HMM TIGR00148 YP_001464062.1 identified by similarity to GB:AAY57854.1; match to protein family HMM PF02441; match to protein family HMM TIGR00421 YP_001464063.1 identified by match to protein family HMM PF01047 YP_001464064.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses YP_001464065.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus YP_001464066.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_001464067.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001464068.1 catalyzes the modification of U13 in tRNA(Glu) YP_001464069.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_001464070.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_001464071.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein YP_001464072.1 identified by similarity to GB:AAG42462.1 YP_001464073.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_001464074.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_001464075.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001464076.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3 YP_001464077.1 identified by match to protein family HMM TIGR00287 YP_001464078.1 identified by match to protein family HMM PF08798; match to protein family HMM TIGR01907 YP_001464079.1 identified by match to protein family HMM TIGR01868; match to protein family HMM TIGR02593 YP_001464080.1 identified by match to protein family HMM TIGR01869 YP_001464081.1 identified by match to protein family HMM TIGR02548 YP_001464082.1 identified by match to protein family HMM TIGR02547 YP_001464083.1 identified by match to protein family HMM PF00271; match to protein family HMM TIGR01587 YP_001464084.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_001464085.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_001464086.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity YP_001464087.1 identified by match to protein family HMM PF01242; match to protein family HMM TIGR00039; match to protein family HMM TIGR03367 YP_001464088.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM PF03486; match to protein family HMM PF07992 YP_001464090.1 identified by match to protein family HMM PF04309 YP_001464091.1 identified by match to protein family HMM PF00766 YP_001464092.1 identified by match to protein family HMM PF01012 YP_001464093.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_001464094.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913 YP_001464095.1 ygcW; identified by match to protein family HMM PF00106 YP_001464096.1 identified by match to protein family HMM PF07690 YP_001464097.1 ygcE; identified by match to protein family HMM PF00370; match to protein family HMM PF02782 YP_001464099.1 identified by glimmer YP_001464100.1 identified by match to protein family HMM PF04536 YP_001464101.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001464102.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001464103.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era YP_001464104.1 MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system YP_001464105.1 part of the MazF-MazE toxin-antitoxin system; conteracts MazF YP_001464106.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP YP_001464107.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_001464108.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_001464109.1 identified by match to protein family HMM PF01188; match to protein family HMM TIGR03247 YP_001464110.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_001464111.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893 YP_001464112.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001464113.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp YP_001464114.1 identified by similarity to SP:Q46919; match to protein family HMM PF04287 YP_001464115.1 SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_001464116.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_001464117.1 identified by glimmer YP_001464118.1 identified by similarity to SP:P0ADS1; match to protein family HMM PF03641 YP_001464119.1 identified by match to protein family HMM TIGR00814 YP_001464120.1 identified by similarity to SP:P16095; match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720 YP_001464121.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups YP_001464122.1 identified by match to protein family HMM PF00465; match to protein family HMM TIGR02638 YP_001464123.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate YP_001464124.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00885 YP_001464125.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose YP_001464126.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR02628 YP_001464127.1 identified by similarity to SP:P0AEN8; match to protein family HMM PF05025 YP_001464128.1 regulates expression of genes involved in L-fucose utilization YP_001464129.1 identified by glimmer YP_001464131.1 identified by match to protein family HMM PF04241 YP_001464132.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_001464133.1 identified by match to protein family HMM PF06004 YP_001464134.1 identified by match to protein family HMM PF00266; match to protein family HMM TIGR03392 YP_001464135.1 identified by similarity to SP:P0AGF2; match to protein family HMM PF02657; match to protein family HMM TIGR03391 YP_001464136.1 identified by match to protein family HMM PF00899 YP_001464137.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_001464138.1 identified by similarity to GB:AAN81830.1; match to protein family HMM PF05591; match to protein family HMM TIGR03358 YP_001464139.1 identified by match to protein family HMM PF05943; match to protein family HMM TIGR03355 YP_001464140.1 identified by similarity to GB:AAN81832.1; match to protein family HMM PF05936; match to protein family HMM TIGR03353 YP_001464141.1 identified by match to protein family HMM TIGR03349 YP_001464142.1 identified by match to protein family HMM PF00691 YP_001464143.1 identified by match to protein family HMM PF05638; match to protein family HMM TIGR03344 YP_001464144.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03345 YP_001464145.1 identified by match to protein family HMM PF04524; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361 YP_001464148.1 identified by match to protein family HMM TIGR03352 YP_001464149.1 identified by similarity to GB:AAN81847.1; match to protein family HMM PF04965; match to protein family HMM TIGR03357 YP_001464150.1 identified by match to protein family HMM PF06812 YP_001464151.1 identified by glimmer YP_001464152.1 identified by similarity to SP:P63883; match to protein family HMM PF01520; match to protein family HMM TIGR01409 YP_001464153.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_001464154.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_001464155.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_001464156.1 identified by similarity to SP:P05458; match to protein family HMM PF00675; match to protein family HMM PF05193 YP_001464157.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination YP_001464158.1 identified by similarity to SP:P08372; match to protein family HMM PF07963; match to protein family HMM TIGR02532 YP_001464159.1 identified by similarity to SP:P08370 YP_001464160.1 identified by similarity to SP:P08371; match to protein family HMM PF07963; match to protein family HMM TIGR02532 YP_001464161.1 identified by similarity to SP:P33554; match to protein family HMM PF07963; match to protein family HMM TIGR02532 YP_001464162.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_001464163.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001464164.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr YP_001464165.1 hydrolyzes diadenosine polyphosphate YP_001464166.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_001464167.1 identified by match to protein family HMM PF03741 YP_001464168.1 identified by similarity to GB:AAV78717.1; match to protein family HMM PF06004 YP_001464169.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH YP_001464170.1 identified by match to protein family HMM PF07690 YP_001464171.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 YP_001464172.1 controls transcription of galETKM YP_001464173.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding YP_001464174.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase YP_001464175.1 identified by glimmer YP_001464176.1 identified by match to protein family HMM PF01177; match to protein family HMM TIGR00035 YP_001464177.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879 YP_001464178.1 identified by glimmer YP_001464179.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate YP_001464180.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate YP_001464181.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_001464182.1 identified by match to protein family HMM PF01490; match to protein family HMM TIGR00814 YP_001464183.1 identified by similarity to GB:AAZ89600.1 YP_001464184.1 identified by match to protein family HMM PF00486 YP_001464186.1 identified by glimmer YP_001464187.1 identified by match to protein family HMM PF07720 YP_001464188.1 identified by match to protein family HMM PF00486; match to protein family HMM PF07719 YP_001464189.1 identified by glimmer YP_001464190.1 identified by match to protein family HMM PF00196 YP_001464191.1 identified by similarity to GB:AAA83039.1 YP_001464192.1 identified by match to protein family HMM PF01514; match to protein family HMM TIGR02544 YP_001464193.1 identified by match to protein family HMM TIGR02554 YP_001464194.1 identified by similarity to SP:P40727; match to protein family HMM PF01312 YP_001464195.1 identified by similarity to GB:BAB60840.1; match to protein family HMM PF01311; match to protein family HMM TIGR01401 YP_001464196.1 identified by similarity to GB:AAZ31292.1; match to protein family HMM PF01313; match to protein family HMM TIGR01403 YP_001464197.1 part of a type III secretory system probably involved in invasion into eukaryotic cells YP_001464198.1 identified by match to protein family HMM PF01052; match to protein family HMM TIGR02551 YP_001464199.1 identified by similarity to GB:BAB37150.1 YP_001464201.1 identified by glimmer YP_001464202.1 identified by match to protein family HMM PF01476; match to protein family HMM PF01551 YP_001464203.1 molybdenum cofactor-binding protein; participates in purine salvage YP_001464204.1 FAD-binding subunit; with XdhA and XdhC participates in purine salvage YP_001464205.1 iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage YP_001464206.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954 YP_001464207.1 ygeW; identified by match to protein family HMM PF00185; match to protein family HMM PF02729 YP_001464208.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate YP_001464209.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases YP_001464210.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position YP_001464211.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_001464212.1 identified by match to protein family HMM PF00364; match to protein family HMM PF02625; match to protein family HMM TIGR03309 YP_001464213.1 identified by similarity to SP:Q46809; match to protein family HMM TIGR03172 YP_001464214.1 identified by similarity to SP:Q46810; match to protein family HMM TIGR03310 YP_001464215.1 identified by glimmer YP_001464216.1 with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase YP_001464217.1 in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS YP_001464218.1 with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain YP_001464219.1 with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration YP_001464220.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173 YP_001464221.1 Catalyzes the deamination of guanine YP_001464222.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_001464223.1 identified by match to protein family HMM PF00037 YP_001464224.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) YP_001464225.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173 YP_001464226.1 identified by glimmer YP_001464227.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate YP_001464228.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001464229.1 5'-3' single-stranded-DNA-specific exonuclease YP_001464230.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity YP_001464231.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001464232.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic YP_001464233.1 identified by match to protein family HMM PF07254 YP_001464234.1 identified by match to protein family HMM PF03937 YP_001464235.1 identified by similarity to GB:AAN81926.1 YP_001464236.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator YP_001464237.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065 YP_001464238.1 identified by match to protein family HMM PF06164 YP_001464239.1 identified by similarity to SP:Q46829; match to protein family HMM PF00232 YP_001464240.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659 YP_001464241.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001464242.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001464243.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001464244.1 identified by glimmer YP_001464245.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM TIGR01988 YP_001464246.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone YP_001464247.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide YP_001464248.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown YP_001464249.1 identified by match to protein family HMM PF05164 YP_001464250.2 ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function YP_001464251.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001464252.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001464253.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_001464254.1 MDM; functions in conversion of succinate to propionate YP_001464255.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins YP_001464256.1 catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA YP_001464257.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001464258.1 identified by similarity to SP:P0ADS8; match to protein family HMM PF04402 YP_001464259.1 Involved in the export of arginine YP_001464260.1 participates in the regulation of osmotic pressure changes within the cel YP_001464261.1 identified by glimmer YP_001464262.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_001464263.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001464264.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_001464265.1 identified by glimmer YP_001464266.1 identified by glimmer YP_001464267.1 identified by match to protein family HMM PF03479 YP_001464270.1 identified by match to protein family HMM PF00005 YP_001464271.1 identified by match to protein family HMM PF00005 YP_001464272.1 identified by similarity to GB:AAZ89673.1 YP_001464273.1 identified by match to protein family HMM PF05068 YP_001464274.1 identified by match to protein family HMM PF03320; match to protein family HMM TIGR00330 YP_001464275.1 identified by similarity to SP:P37084; match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001464276.1 identified by similarity to SP:P69826; match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851 YP_001464277.1 TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein YP_001464278.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001464279.1 identified by match to protein family HMM PF01435 YP_001464280.1 identified by similarity to GB:AAV79415.1; match to protein family HMM PF07071 YP_001464281.1 identified by match to protein family HMM PF01212; match to protein family HMM PF03841; match to protein family HMM TIGR01437 YP_001464282.1 identified by glimmer YP_001464283.1 identified by match to protein family HMM PF03613 YP_001464284.1 identified by match to protein family HMM PF03609 YP_001464285.1 identified by match to protein family HMM PF03830 YP_001464286.1 identified by match to protein family HMM PF03610 YP_001464287.1 identified by match to protein family HMM PF00158; match to protein family HMM PF00874 YP_001464288.1 catalyzes the formation of putrescine from agmatine YP_001464290.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_001464291.1 identified by similarity to SP:P64567 YP_001464292.1 identified by glimmer YP_001464293.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001464294.1 identified by glimmer YP_001464295.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879 YP_001464296.1 identified by match to protein family HMM PF03926 YP_001464297.1 identified by similarity to SP:P25736; match to protein family HMM PF04231 YP_001464298.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001464299.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001464300.1 identified by similarity to SP:P0A8W7; match to protein family HMM PF02622 YP_001464301.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001464302.1 identified by glimmer YP_001464303.1 identified by match to protein family HMM PF00437; match to protein family HMM TIGR01420 YP_001464304.1 identified by match to protein family HMM PF01168; match to protein family HMM TIGR00044 YP_001464305.1 identified by match to protein family HMM PF02325 YP_001464306.1 identified by similarity to GB:AAP18250.1; match to protein family HMM PF02594; match to protein family HMM TIGR00251 YP_001464307.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001464308.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001464309.1 identified by match to protein family HMM PF06717 YP_001464310.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis YP_001464311.1 identified by similarity to SP:P0ADS9 YP_001464312.1 identified by glimmer YP_001464313.1 identified by match to protein family HMM PF04320 YP_001464314.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001464315.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01084 YP_001464316.1 identified by similarity to GB:AAN81997.1 YP_001464317.1 identified by match to protein family HMM PF04362 YP_001464318.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_001464319.1 identified by match to protein family HMM PF03825; match to protein family HMM PF07690; match to protein family HMM TIGR00889 YP_001464320.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_001464321.1 identified by match to protein family HMM PF04474 YP_001464322.1 identified by match to protein family HMM PF00589 YP_001464323.1 identified by match to protein family HMM PF03811 YP_001464324.1 identified by match to protein family HMM PF03400 YP_001464325.1 identified by similarity to GB:AAS63192.1 YP_001464326.1 identified by glimmer YP_001464327.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271 YP_001464328.1 identified by match to protein family HMM PF00004 YP_001464329.1 identified by match to protein family HMM PF00082 YP_001464330.1 identified by match to protein family HMM PF01555 YP_001464331.1 identified by match to protein family HMM PF04851 YP_001464332.1 identified by glimmer YP_001464333.1 identified by match to protein family HMM PF00078; match to protein family HMM PF08388 YP_001464334.1 identified by match to protein family HMM PF01527 YP_001464335.1 identified by similarity to GB:ABA74402.1 YP_001464336.1 identified by match to protein family HMM PF07728 YP_001464337.1 identified by glimmer YP_001464338.1 identified by similarity to GB:AAK00467.1 YP_001464339.1 identified by match to protein family HMM PF05321 YP_001464340.1 identified by similarity to GB:AAN44467.1 YP_001464341.1 identified by similarity to GB:AAL08467.1 YP_001464342.1 identified by similarity to GB:AAZ76440.1; match to protein family HMM PF00665; match to protein family HMM PF02796 YP_001464343.1 identified by match to protein family HMM PF00308; match to protein family HMM PF01695 YP_001464344.1 identified by similarity to SP:P15025; match to protein family HMM PF00665 YP_001464345.1 identified by match to protein family HMM PF03050 YP_001464346.1 identified by match to protein family HMM PF05717 YP_001464347.1 identified by match to protein family HMM PF01527 YP_001464348.1 identified by match to protein family HMM PF01926 YP_001464349.1 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414 YP_001464350.1 identified by match to protein family HMM PF06067 YP_001464351.1 identified by match to protein family HMM PF03230 YP_001464352.1 identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608 YP_001464353.1 identified by similarity to GB:AAP18295.1; match to protein family HMM PF06174 YP_001464354.1 identified by similarity to GB:BAB36228.1; match to protein family HMM PF06154 YP_001464355.1 identified by match to protein family HMM PF06755 YP_001464356.1 identified by similarity to GB:AAN83011.1; match to protein family HMM PF06117 YP_001464357.1 identified by similarity to GB:CAE85207.1 YP_001464358.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899 YP_001464359.1 identified by match to protein family HMM PF07515 YP_001464361.1 identified by match to protein family HMM PF02369 YP_001464362.1 identified by glimmer YP_001464363.1 identified by glimmer YP_001464364.1 identified by match to protein family HMM PF00580 YP_001464365.1 identified by glimmer YP_001464366.1 identified by similarity to GB:CAE13457.1 YP_001464367.1 identified by match to protein family HMM PF01527 YP_001464368.1 identified by match to protein family HMM PF05717 YP_001464369.1 identified by match to protein family HMM PF03050 YP_001464370.1 identified by similarity to SP:P15026; match to protein family HMM PF01695 YP_001464371.1 identified by match to protein family HMM PF00665 YP_001464372.1 identified by similarity to SP:P0ACB0; match to protein family HMM PF00772; match to protein family HMM PF03796; match to protein family HMM TIGR00665 YP_001464373.1 identified by glimmer YP_001464374.1 identified by glimmer YP_001464375.1 identified by glimmer YP_001464377.1 identified by match to protein family HMM PF00589 YP_001464378.1 identified by similarity to SP:P21867; match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001464379.1 identified by similarity to SP:P16551; match to protein family HMM PF02065 YP_001464380.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments YP_001464381.1 identified by match to protein family HMM PF00251; match to protein family HMM PF08244; match to protein family HMM TIGR01322 YP_001464382.1 identified by similarity to GB:AAB71432.1 YP_001464383.1 identified by match to protein family HMM PF03050 YP_001464384.1 identified by match to protein family HMM PF05717 YP_001464385.1 identified by match to protein family HMM PF01527 YP_001464386.1 identified by similarity to SP:P0ACF8; match to protein family HMM PF00816 YP_001464387.1 identified by glimmer YP_001464388.1 identified by match to protein family HMM PF05930 YP_001464389.1 identified by glimmer YP_001464390.1 identified by glimmer YP_001464391.1 identified by glimmer YP_001464392.1 identified by similarity to GB:CAD42091.1 YP_001464393.1 identified by glimmer YP_001464394.1 identified by glimmer YP_001464395.1 identified by glimmer YP_001464396.1 identified by glimmer YP_001464397.1 identified by glimmer YP_001464398.1 identified by glimmer YP_001464399.1 identified by match to protein family HMM PF01926 YP_001464400.1 identified by glimmer YP_001464401.1 identified by match to protein family HMM PF08279 YP_001464402.1 identified by glimmer YP_001464403.1 identified by glimmer YP_001464404.1 identified by match to protein family HMM PF06006 YP_001464405.1 identified by match to protein family HMM PF06067 YP_001464406.1 identified by match to protein family HMM PF03230 YP_001464407.1 identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608 YP_001464408.1 identified by match to protein family HMM PF06174 YP_001464409.1 identified by similarity to GB:AAP18296.1; match to protein family HMM PF06154 YP_001464410.1 identified by match to protein family HMM PF06755 YP_001464411.1 identified by similarity to GB:ABB61173.1 YP_001464412.1 identified by match to protein family HMM PF06117 YP_001464413.1 identified by similarity to GB:BAB34832.1 YP_001464414.1 identified by similarity to GB:CAE16642.1; match to protein family HMM PF08843 YP_001464415.1 identified by similarity to SP:P41851; match to protein family HMM PF04612 YP_001464416.1 similar to general secretory pathway protein L YP_001464417.1 identified by match to protein family HMM PF03934 YP_001464418.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR01711; match to protein family HMM TIGR02532 YP_001464419.1 identified by match to protein family HMM PF02501; match to protein family HMM PF07963; match to protein family HMM TIGR01707; match to protein family HMM TIGR02532 YP_001464420.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR01708; match to protein family HMM TIGR02532 YP_001464421.1 identified by match to protein family HMM PF07963; match to protein family HMM PF08334; match to protein family HMM TIGR01710; match to protein family HMM TIGR02532 YP_001464422.1 identified by match to protein family HMM PF00482; match to protein family HMM TIGR02120 YP_001464423.1 identified by match to protein family HMM PF00437; match to protein family HMM TIGR02533 YP_001464424.1 identified by match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM TIGR02517 YP_001464425.1 part of the general (type II) secretion pathway (GSP), a signal sequence-dependent process responsible for protein export; involved in trans-location of exoproteins from the cytoplasm to the periplasm YP_001464427.1 identified by similarity to SP:P31712; match to protein family HMM PF01478; match to protein family HMM PF06750 YP_001464428.1 identified by glimmer YP_001464429.1 identified by glimmer YP_001464430.1 identified by glimmer YP_001464431.1 identified by match to protein family HMM PF02652; match to protein family HMM TIGR00795 YP_001464432.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA YP_001464433.1 identified by match to protein family HMM PF03928 YP_001464434.1 identified by similarity to SP:P52074; match to protein family HMM PF00037; match to protein family HMM PF02754 YP_001464435.1 identified by match to protein family HMM PF01565 YP_001464436.1 identified by similarity to SP:P52075; match to protein family HMM PF01565; match to protein family HMM PF02913; match to protein family HMM TIGR00387 YP_001464437.1 identified by similarity to SP:P0ACL5; match to protein family HMM PF00392; match to protein family HMM PF07729 YP_001464438.1 identified by glimmer YP_001464439.1 activates fatty acids by binding to coenzyme A YP_001464440.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF05368; match to protein family HMM PF07993 YP_001464441.1 identified by match to protein family HMM PF00550 YP_001464442.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00202 YP_001464443.1 identified by match to protein family HMM PF03739 YP_001464444.1 identified by match to protein family HMM PF03739 YP_001464445.1 identified by match to protein family HMM TIGR01626 YP_001464446.1 identified by similarity to GB:AAN82163.1 YP_001464447.1 identified by match to protein family HMM PF01943 YP_001464448.1 identified by similarity to GB:AAV89941.1 YP_001464451.1 identified by match to protein family HMM PF01384 YP_001464452.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction YP_001464453.1 YghU; B2989; one of eight glutathione transferases from E. coli YP_001464454.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001464455.1 identified by glimmer YP_001464456.1 identified by match to protein family HMM PF01455; match to protein family HMM TIGR00074 YP_001464457.1 plays a role in hydrogenase nickel cofactor insertion YP_001464459.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC) YP_001464460.1 involved in hydrogen uptake YP_001464461.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits YP_001464462.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2 YP_001464463.1 identified by glimmer YP_001464464.1 involved in hydrogen uptake YP_001464465.1 identified by similarity to SP:P64577 YP_001464466.1 identified by match to protein family HMM PF01738; match to protein family HMM PF08840 YP_001464467.1 identified by match to protein family HMM PF00248 YP_001464468.1 identified by match to protein family HMM PF03350; match to protein family HMM TIGR00645 YP_001464469.1 identified by match to protein family HMM PF00106 YP_001464470.1 identified by glimmer YP_001464471.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_001464472.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_001464473.1 catalyzes the formation of L-homocysteine from cystathionine YP_001464474.1 identified by similarity to SP:P0AA60; match to protein family HMM PF09335 YP_001464475.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06719 YP_001464476.1 identified by similarity to SP:Q46856; match to protein family HMM PF00465 YP_001464477.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate YP_001464478.1 identified by glimmer YP_001464481.1 identified by match to protein family HMM PF04055; match to protein family HMM PF08497 YP_001464482.1 identified by similarity to SP:P26648; match to protein family HMM PF07731; match to protein family HMM PF07732; match to protein family HMM TIGR01409 YP_001464483.1 identified by similarity to SP:P26647; match to protein family HMM PF01553; match to protein family HMM TIGR00530 YP_001464484.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001464485.1 identified by match to protein family HMM PF06445 YP_001464486.1 identified by match to protein family HMM PF04076; match to protein family HMM TIGR00156 YP_001464487.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes YP_001464488.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_001464489.1 identified by similarity to SP:P0AEY5; match to protein family HMM PF02525 YP_001464490.1 identified by similarity to PDB:1R6Y_A; match to protein family HMM PF03992 YP_001464491.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001464492.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_001464493.1 identified by match to protein family HMM PF00149; match to protein family HMM PF08413 YP_001464494.1 identified by similarity to SP:P0ADV0; match to protein family HMM PF06853 YP_001464495.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_001464496.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_001464497.1 identified by similarity to GB:ABB63213.1 YP_001464498.1 identified by similarity to GB:ABG71111.1 YP_001464499.1 identified by match to protein family HMM PF03738 YP_001464500.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine YP_001464501.1 identified by match to protein family HMM PF02535 YP_001464502.1 identified by similarity to GB:AAG58180.1 YP_001464503.1 DHBP synthase; functions during riboflavin biosynthesis YP_001464504.1 identified by match to protein family HMM PF04380 YP_001464505.1 identified by match to protein family HMM PF00419 YP_001464506.1 identified by match to protein family HMM PF00577 YP_001464507.1 identified by match to protein family HMM PF00345 YP_001464508.1 identified by similarity to GB:AAZ89767.1 YP_001464509.1 Involved in glycogen synthesis. May be involved in glycogen priming YP_001464510.1 identified by match to protein family HMM PF07290 YP_001464511.1 identified by match to protein family HMM PF01145 YP_001464512.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_001464513.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_001464514.1 identified by match to protein family HMM PF01928; match to protein family HMM PF05235 YP_001464516.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases YP_001464517.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001464518.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin YP_001464519.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_001464520.1 activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol YP_001464521.1 identified by glimmer YP_001464522.1 Involved in the tartrate degradation pathway YP_001464523.1 Involved in the tartrate degradation pathway YP_001464524.1 identified by match to protein family HMM PF00939; match to protein family HMM TIGR00785 YP_001464525.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001464526.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001464527.1 synthesizes RNA primers at the replication forks YP_001464528.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_001464529.1 identified by similarity to SP:P0A9H1; match to protein family HMM PF03167 YP_001464530.1 identified by match to protein family HMM PF04954; match to protein family HMM PF08021 YP_001464531.1 identified by glimmer YP_001464532.1 identified by match to protein family HMM PF03551 YP_001464533.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF08447; match to protein family HMM TIGR00229 YP_001464534.1 identified by glimmer YP_001464535.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate YP_001464536.1 identified by match to protein family HMM PF01588 YP_001464537.1 identified by similarity to SP:P06846; match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001464538.1 in Escherichia coli this is the second beta-galactosidase system YP_001464539.1 in Escherichia coli this is the second beta-galactosidase system YP_001464540.1 identified by match to protein family HMM PF00324 YP_001464541.1 identified by similarity to GB:AAZ89711.1 YP_001464542.1 identified by similarity to SP:P42592 YP_001464543.1 identified by similarity to SP:P42593; match to protein family HMM PF00724; match to protein family HMM PF01266; match to protein family HMM PF07992 YP_001464544.1 identified by match to protein family HMM PF01381 YP_001464545.1 identified by similarity to GB:AAN82286.1 YP_001464546.1 identified by match to protein family HMM PF05175; match to protein family HMM PF08242 YP_001464547.1 identified by similarity to SP:P42597; match to protein family HMM PF01863 YP_001464548.1 identified by match to protein family HMM PF02698 YP_001464549.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_001464550.1 identified by similarity to SP:P42601; match to protein family HMM PF03741 YP_001464551.1 identified by glimmer YP_001464552.1 involved in the import of serine and threonine coupled with the import of sodium YP_001464554.1 identified by similarity to SP:P42604; match to protein family HMM PF04295; match to protein family HMM PF08666 YP_001464555.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism YP_001464556.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893 YP_001464559.1 identified by match to protein family HMM PF04449 YP_001464561.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization. YP_001464562.1 identified by similarity to SP:P0AA63; match to protein family HMM PF09335 YP_001464563.1 identified by similarity to GB:AAZ89832.1 YP_001464564.1 identified by glimmer YP_001464565.1 identified by similarity to SP:P42616; match to protein family HMM PF06476 YP_001464566.1 identified by similarity to GB:CAD07753.1; match to protein family HMM PF05957 YP_001464567.1 identified by similarity to GB:ABE08983.1 YP_001464568.1 identified by similarity to GB:ABB63285.1 YP_001464569.1 identified by match to protein family HMM PF07681 YP_001464571.1 identified by glimmer YP_001464572.1 identified by match to protein family HMM PF05656 YP_001464573.1 identified by glimmer YP_001464574.1 identified by similarity to SP:P64592; match to protein family HMM PF05656 YP_001464575.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001464576.1 identified by match to protein family HMM PF02678 YP_001464577.1 identified by similarity to GB:ABB63296.1 YP_001464578.1 identified by glimmer YP_001464579.1 identified by match to protein family HMM PF06354 YP_001464580.1 identified by match to protein family HMM TIGR00814 YP_001464581.1 identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720 YP_001464582.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004 YP_001464583.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255 YP_001464584.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism YP_001464585.1 involved in the import of threonine and serine in combination with the import of a proton YP_001464586.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic YP_001464587.1 regulates the tdcABCDEFG operon which is involved in amino acid degradation YP_001464588.1 participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon YP_001464589.1 identified by glimmer YP_001464590.1 identified by glimmer YP_001464591.1 identified by similarity to GB:BAB37424.1 YP_001464592.1 identified by similarity to GB:ABB67500.1 YP_001464593.1 identified by glimmer YP_001464595.1 identified by similarity to SP:P23524; match to protein family HMM PF02595; match to protein family HMM TIGR00045 YP_001464596.1 catalyzes the reduction of tartronate semialdehyde to glycerate YP_001464597.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate YP_001464598.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893 YP_001464599.1 identified by glimmer YP_001464600.1 identified by glimmer YP_001464601.1 identified by similarity to SP:P39829; match to protein family HMM PF04295; match to protein family HMM PF08666 YP_001464602.1 SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation YP_001464603.1 identified by similarity to GB:AAZ89862.1 YP_001464604.1 transcriptional repressor for the agaZVWA and agaSYBCDI operons YP_001464605.1 identified by match to protein family HMM PF08013; match to protein family HMM TIGR02810 YP_001464606.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport YP_001464607.1 identified by match to protein family HMM PF03609 YP_001464608.1 identified by match to protein family HMM PF03613 YP_001464609.1 identified by similarity to GB:AAF81086.1; match to protein family HMM PF03610 YP_001464610.1 identified by match to protein family HMM PF01979; match to protein family HMM TIGR00221 YP_001464611.1 identified by match to protein family HMM PF01380; match to protein family HMM TIGR02815 YP_001464612.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway YP_001464613.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport YP_001464614.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport YP_001464615.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport YP_001464616.1 identified by match to protein family HMM PF01182 YP_001464617.1 identified by match to protein family HMM PF00419 YP_001464618.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001464619.1 identified by match to protein family HMM PF00577 YP_001464621.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096 YP_001464622.1 identified by match to protein family HMM PF04348 YP_001464623.1 identified by match to protein family HMM PF02021; match to protein family HMM TIGR00252 YP_001464624.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein YP_001464625.1 identified by match to protein family HMM PF04972 YP_001464626.1 identified by match to protein family HMM PF01370 YP_001464627.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01382 YP_001464628.1 identified by similarity to GB:AAV78968.1 YP_001464629.1 identified by match to protein family HMM PF01541 YP_001464630.1 identified by match to protein family HMM PF00583 YP_001464631.1 identified by match to protein family HMM PF02036 YP_001464632.1 identified by match to protein family HMM PF01136 YP_001464633.1 identified by match to protein family HMM PF01136 YP_001464634.1 identified by match to protein family HMM PF00296 YP_001464635.1 tryptophan transporter of high affinity YP_001464636.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division YP_001464637.1 identified by glimmer YP_001464638.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_001464639.1 identified by glimmer YP_001464640.1 identified by similarity to SP:P05055; match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726 YP_001464641.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001464642.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001464643.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001464644.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001464645.1 identified by similarity to GB:AAW76474.1 YP_001464646.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001464647.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001464648.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis YP_001464649.1 identified by match to protein family HMM PF00884 YP_001464650.1 identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810 YP_001464651.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001464652.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate YP_001464653.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins YP_001464654.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_001464655.1 RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability YP_001464656.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001464657.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_001464658.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001464659.1 identified by match to protein family HMM PF00892 YP_001464660.1 involved in the peptidyltransferase reaction during translation YP_001464661.1 identified by similarity to GB:AAN82384.1 YP_001464662.1 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061 YP_001464663.1 identified by similarity to SP:P0AD57; match to protein family HMM PF00348 YP_001464664.1 activator of maltose metabolism genes YP_001464665.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001464666.1 identified by match to protein family HMM PF01722 YP_001464667.1 identified by similarity to GB:AAN82389.1 YP_001464669.1 identified by similarity to GB:AAN82391.1 YP_001464670.1 identified by match to protein family HMM PF05494 YP_001464671.1 identified by match to protein family HMM PF02470 YP_001464672.1 identified by match to protein family HMM PF02405; match to protein family HMM TIGR00056 YP_001464673.1 ATP-binding subunit of a ABC toluene efflux transporter YP_001464674.1 YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers YP_001464675.1 identified by similarity to SP:P45395; match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393 YP_001464676.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_001464677.1 identified by match to protein family HMM PF06835 YP_001464678.1 LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system YP_001464679.1 identified by similarity to SP:P0A9V1; match to protein family HMM PF00005 YP_001464680.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_001464681.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing YP_001464682.1 identified by similarity to SP:P69829; match to protein family HMM PF00359; match to protein family HMM TIGR01419 YP_001464683.1 identified by match to protein family HMM PF03668 YP_001464684.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_001464685.1 identified by similarity to SP:P64611 YP_001464686.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_001464687.1 identified by similarity to SP:P0ABU5; match to protein family HMM PF01965 YP_001464688.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA YP_001464689.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR01212 YP_001464690.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_001464691.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_001464692.1 identified by similarity to GB:ABB63386.1; match to protein family HMM PF06250 YP_001464693.1 identified by similarity to SP:P0AF97; match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_001464694.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein YP_001464695.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_001464696.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00891 YP_001464697.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid YP_001464698.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization YP_001464699.1 YhcL; uncharacterized member of the DcuC family of anaerobic dicarboxylate transporters; probable role in transport of carboxylates across the inner membrane from the periplasm; its encoding gene is not essential for growth and is probably cryptic YP_001464700.1 identified by glimmer YP_001464701.1 identified by match to protein family HMM PF04386 YP_001464702.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_001464703.1 forms a direct contact with the tRNA during translation YP_001464704.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001464705.1 identified by match to protein family HMM PF03969 YP_001464706.1 identified by match to protein family HMM PF06295 YP_001464707.1 identified by similarity to SP:P39099; match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037 YP_001464708.1 identified by match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02038 YP_001464709.1 oxidizes malate to oxaloacetate YP_001464710.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_001464711.1 identified by similarity to SP:P0AB40; match to protein family HMM PF07338 YP_001464712.1 identified by similarity to SP:P64616 YP_001464713.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_001464714.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_001464715.2 membrane protein AaeX; the gene is a member of the aaeXAB operon YP_001464716.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001464717.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA YP_001464718.1 identified by match to protein family HMM TIGR02099 YP_001464719.1 involved in the processing of the 5'end of 16S rRNA YP_001464720.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001464721.1 part of cell wall structural complex MreBCD; transmembrane component YP_001464723.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001464724.1 functions in MreBCD complex in some organisms YP_001464725.1 identified by similarity to GB:AAN82447.1 YP_001464726.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_001464727.1 identified by similarity to PDB:1O8C_A; match to protein family HMM PF00107; match to protein family HMM PF01262; match to protein family HMM PF08240; match to protein family HMM TIGR02823 YP_001464728.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001464729.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001464730.1 identified by match to protein family HMM PF06196 YP_001464731.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_001464732.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001464733.1 identified by glimmer YP_001464734.1 identified by similarity to SP:P0ABT5; match to protein family HMM PF01207; match to protein family HMM TIGR00737 YP_001464735.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_001464736.1 identified by match to protein family HMM PF01555 YP_001464737.1 identified by similarity to GB:AAN82469.1 YP_001464738.1 identified by similarity to SP:P0ACT2; match to protein family HMM PF00440; match to protein family HMM PF08361 YP_001464739.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730 YP_001464740.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_001464744.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001464745.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001464746.1 yhdZ; identified by match to protein family HMM PF00005 YP_001464748.1 identified by similarity to SP:P45795; match to protein family HMM PF07369 YP_001464749.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001464750.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA YP_001464751.1 identified by match to protein family HMM PF01396 YP_001464752.1 identified by similarity to SP:P66822; match to protein family HMM PF04361 YP_001464753.1 identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732 YP_001464754.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001464755.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_001464756.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase YP_001464757.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_001464758.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_001464759.1 identified by match to protein family HMM PF03889 YP_001464760.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_001464761.1 identified by similarity to SP:P36677 YP_001464762.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001464763.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001464764.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001464765.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001464766.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001464767.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_001464768.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001464769.1 late assembly protein YP_001464770.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001464771.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001464772.1 binds 5S rRNA along with protein L5 and L25 YP_001464773.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001464774.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001464775.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001464776.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001464777.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001464778.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001464779.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001464780.1 one of the stabilizing components for the large ribosomal subunit YP_001464781.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001464782.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001464783.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001464784.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001464785.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001464786.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001464787.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001464788.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001464789.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001464790.1 identified by match to protein family HMM PF01478 YP_001464791.1 iron storage protein YP_001464792.1 identified by similarity to SP:P0AE56; match to protein family HMM PF04324 YP_001464793.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001464794.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001464795.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001464796.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001464797.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001464798.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001464799.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001464800.1 identified by match to protein family HMM PF08348 YP_001464801.1 rotamase YP_001464802.1 identified by match to protein family HMM PF04102 YP_001464803.1 rotamase YP_001464804.1 identified by similarity to SP:P0ADW8; match to protein family HMM TIGR02443 YP_001464805.1 involved in potassium efflux YP_001464806.1 required for KefB activity YP_001464807.1 identified by match to protein family HMM PF00005 YP_001464808.1 identified by match to protein family HMM PF00561 YP_001464809.1 identified by match to protein family HMM PF06794 YP_001464810.1 identified by match to protein family HMM PF00485 YP_001464811.1 identified by match to protein family HMM PF02566 YP_001464812.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_001464813.1 identified by match to protein family HMM PF05976; match to protein family HMM TIGR01667 YP_001464814.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_001464815.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity YP_001464816.1 identified by similarity to SP:P20605; match to protein family HMM PF02661 YP_001464817.1 identified by similarity to SP:P20752; match to protein family HMM PF00160 YP_001464818.1 identified by match to protein family HMM PF07690 YP_001464819.1 identified by similarity to GB:AAX67313.1 YP_001464820.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM PF04324; match to protein family HMM PF07992; match to protein family HMM TIGR02374 YP_001464821.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations YP_001464822.1 member of the FNT family of formate and nitrite transporters YP_001464823.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin YP_001464825.1 inner membrane protein possibly involved in fructoselysine transport; member of the flr operon YP_001464826.1 catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine YP_001464827.1 YhfOP; YhfP; YhfO; FrlC; catalyzes the interconversion of fructoselysine and psicoselysine YP_001464828.1 identified by match to protein family HMM PF00294 YP_001464829.1 may act as a transcriptional regulator of a fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes YP_001464830.1 identified by similarity to GB:ABB67851.1 YP_001464831.1 identified by similarity to SP:P45546 YP_001464833.1 phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE) YP_001464834.1 identified by match to protein family HMM PF01676; match to protein family HMM PF08342 YP_001464835.1 identified by match to protein family HMM PF01168 YP_001464837.1 identified by similarity to OMNI:NTL01SF3196 YP_001464838.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001464839.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_001464840.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_001464841.1 identified by match to protein family HMM PF02086; match to protein family HMM TIGR00571 YP_001464842.1 identified by similarity to SP:P11557; match to protein family HMM PF05036 YP_001464843.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001464844.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001464845.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa YP_001464848.1 identified by match to protein family HMM PF05137 YP_001464849.1 identified by similarity to SP:P45753 YP_001464850.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits YP_001464851.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_001464852.1 identified by glimmer YP_001464853.1 identified by similarity to SP:P45800; match to protein family HMM PF07095 YP_001464854.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509 YP_001464855.1 identified by similarity to SP:P0ACG8; match to protein family HMM PF01479 YP_001464856.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_001464857.1 identified by similarity to SP:P45804 YP_001464858.1 identified by glimmer YP_001464859.1 identified by similarity to GB:AAN44882.1 YP_001464860.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001464861.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_001464862.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_001464863.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001464864.1 identified by match to protein family HMM PF00575 YP_001464865.1 identified by glimmer YP_001464866.1 identified by match to protein family HMM PF04023 YP_001464867.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake YP_001464868.1 identified by match to protein family HMM PF09012 YP_001464869.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_001464870.1 Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis YP_001464871.1 involved in high-affinity gluconate transport YP_001464872.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_001464873.1 identified by glimmer YP_001464874.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_001464875.1 amylomaltase; acts to release glucose from maltodextrins YP_001464876.1 identified by similarity to SP:P00490; match to protein family HMM PF00343; match to protein family HMM TIGR02093 YP_001464877.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides YP_001464878.1 catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester YP_001464879.1 identified by glimmer YP_001464880.1 identified by similarity to SP:P46850; match to protein family HMM PF01139 YP_001464881.1 identified by similarity to SP:P38035; match to protein family HMM PF00158; match to protein family HMM PF06956; match to protein family HMM PF07728 YP_001464882.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism YP_001464883.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity YP_001464884.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine YP_001464885.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_001464886.1 identified by similarity to GB:AAN82642.1 YP_001464890.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093 YP_001464891.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_001464892.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_001464893.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen YP_001464894.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_001464895.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001464896.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP) YP_001464897.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_001464898.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate YP_001464899.1 identified by similarity to SP:P0ACP5; match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001464900.1 identified by match to protein family HMM PF02678; match to protein family HMM PF07883 YP_001464901.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_001464902.1 identified by glimmer YP_001464903.1 YhhY; regulated by the fur regulator; unknown function YP_001464904.1 identified by match to protein family HMM PF01844; match to protein family HMM PF05638; match to protein family HMM TIGR03344 YP_001464906.1 identified by glimmer YP_001464907.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides YP_001464908.1 identified by glimmer YP_001464910.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate YP_001464911.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_001464912.1 with UgpABC is involved in uptake of glycerol-3-phosphate YP_001464913.1 with UgpEC is involved in the uptake of glycerol-3-phosphate YP_001464914.1 with UgpACE is involved in the uptake of glycerol-3-phosphate YP_001464915.1 identified by glimmer YP_001464916.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001464917.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001464918.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001464919.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter YP_001464920.1 identified by match to protein family HMM PF01094 YP_001464921.1 identified by glimmer YP_001464922.1 identified by match to protein family HMM PF00583 YP_001464924.1 identified by similarity to GB:AAX67401.1; match to protein family HMM PF08681 YP_001464925.1 identified by match to protein family HMM PF01094 YP_001464926.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_001464927.1 ABC transporter membrane protein YP_001464928.1 ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions YP_001464929.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins YP_001464930.1 catalyzes the methylation of 16S rRNA at position G966 YP_001464931.1 identified by match to protein family HMM PF06611 YP_001464932.1 identified by similarity to GB:CAG77246.1 YP_001464933.1 identified by match to protein family HMM PF07947 YP_001464934.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury YP_001464935.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs YP_001464936.1 identified by match to protein family HMM PF02592; match to protein family HMM TIGR00697 YP_001464938.1 identified by match to protein family HMM PF07690 YP_001464939.1 identified by match to protein family HMM PF01594 YP_001464940.1 identified by similarity to SP:P37623; match to protein family HMM PF01648 YP_001464941.1 identified by match to protein family HMM PF00496; match to protein family HMM TIGR02294 YP_001464942.1 with NikACDE is involved in nickel transport into the cell YP_001464943.1 identified by glimmer YP_001464944.1 with NikABDE is involved in nickel transport into the cell YP_001464945.1 identified by glimmer YP_001464946.1 with NikABCE is involved in nickel transport into the cell YP_001464947.1 with NikABCD is involved with nickel transport into the cell YP_001464948.1 Inhibits transcription at high concentrations of nickel YP_001464949.1 identified by match to protein family HMM PF05534 YP_001464950.1 identified by match to protein family HMM PF01061 YP_001464951.1 identified by match to protein family HMM PF00005; match to protein family HMM PF01061 YP_001464952.1 identified by match to protein family HMM PF00529 YP_001464953.1 identified by similarity to GB:AAP19219.1 YP_001464954.1 identified by similarity to GB:AAZ90271.1 YP_001464956.1 identified by glimmer YP_001464957.1 identified by match to protein family HMM PF01266; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR00275 YP_001464958.1 identified by match to protein family HMM PF01384 YP_001464959.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_001464960.1 identified by similarity to SP:P0AED0; match to protein family HMM PF00582 YP_001464961.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function YP_001464962.1 predicted SAM-dependent methyltransferase YP_001464963.1 identified by similarity to SP:P27298; match to protein family HMM PF01432 YP_001464964.1 identified by similarity to SP:P37634; match to protein family HMM PF04378 YP_001464965.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_001464966.1 identified by glimmer YP_001464967.1 regulates the expression of of the arsRBC involved in resistance to arsenic YP_001464968.1 identified by match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM TIGR00935 YP_001464969.1 identified by similarity to SP:P08692; match to protein family HMM PF03960; match to protein family HMM TIGR00014 YP_001464970.1 identified by glimmer YP_001464971.1 identified by match to protein family HMM PF01022 YP_001464972.1 identified by match to protein family HMM PF03773 YP_001464973.1 identified by similarity to GB:ABB67989.1 YP_001464975.1 identified by match to protein family HMM PF03843; match to protein family HMM TIGR00752 YP_001464976.1 identified by similarity to SP:P37195; match to protein family HMM PF00196 YP_001464977.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli YP_001464979.1 inactive form YP_001464980.1 identified by similarity to SP:P0AET7 YP_001464981.1 identified by similarity to SP:P63204 YP_001464982.1 with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds YP_001464983.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_001464984.1 identified by similarity to SP:P63201; match to protein family HMM PF00165 YP_001464985.1 identified by glimmer YP_001464986.1 regulates genes in response to acid and/or during stationary phase YP_001464987.1 identified by glimmer YP_001464988.1 identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788 YP_001464989.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose YP_001464990.1 identified by match to protein family HMM PF00196; match to protein family HMM PF04545; match to protein family HMM PF08281 YP_001464991.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001464992.1 identified by match to protein family HMM PF03631; match to protein family HMM TIGR00766 YP_001464993.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_001464994.1 identified by match to protein family HMM PF05170 YP_001464995.1 in Escherichia coli this protein is involved in flagellar function YP_001464996.1 identified by similarity to SP:P45416; match to protein family HMM PF00294 YP_001464997.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193 YP_001464998.1 involved in the transport of C4-dicarboxylates across the membrane YP_001464999.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase from E. coli YP_001465000.1 cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA YP_001465001.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans YP_001465002.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP) YP_001465003.1 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis YP_001465004.1 identified by match to protein family HMM PF06564; match to protein family HMM TIGR03371 YP_001465006.1 identified by match to protein family HMM TIGR03369 YP_001465007.1 identified by similarity to SP:P0ADJ5 YP_001465008.1 identified by similarity to GB:BAB37841.1; match to protein family HMM TIGR03368 YP_001465009.1 identified by glimmer YP_001465010.1 identified by similarity to GB:AAN45023.1 YP_001465011.1 identified by glimmer YP_001465012.1 identified by match to protein family HMM TIGR00814 YP_001465013.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_001465014.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF YP_001465015.1 identified by match to protein family HMM PF00528 YP_001465016.1 transports peptides consisting of two or three amino acids YP_001465018.1 identified by match to protein family HMM PF00496 YP_001465019.1 identified by glimmer YP_001465020.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001465021.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide YP_001465022.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00890 YP_001465023.1 identified by similarity to SP:P37663 YP_001465024.1 constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine YP_001465025.1 identified by match to protein family HMM PF00583 YP_001465026.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509 YP_001465027.1 identified by similarity to SP:P37665; match to protein family HMM PF00691; match to protein family HMM PF05433 YP_001465028.1 identified by glimmer YP_001465029.1 identified by similarity to SP:P37666; match to protein family HMM PF00389; match to protein family HMM PF02826 YP_001465031.1 identified by similarity to SP:P0A9V5 YP_001465032.1 identified by match to protein family HMM PF00313 YP_001465033.1 identified by match to protein family HMM PF01848 YP_001465034.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001465035.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001465037.1 identified by match to protein family HMM PF01757 YP_001465038.1 identified by match to protein family HMM PF05360 YP_001465039.1 identified by match to protein family HMM PF05360 YP_001465040.1 identified by similarity to SP:P29444; match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR01312 YP_001465041.1 catalyzes the interconversion of D-xylose to D-xylulose YP_001465042.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity YP_001465043.1 with XylFH is part of the high affinity xylose ABC transporter YP_001465044.1 identified by match to protein family HMM PF02653 YP_001465045.1 identified by match to protein family HMM PF00165 YP_001465046.1 identified by match to protein family HMM PF01832 YP_001465047.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds YP_001465048.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis YP_001465049.1 identified by match to protein family HMM PF00037 YP_001465050.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339 YP_001465051.1 NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate YP_001465052.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_001465053.1 membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO YP_001465054.1 identified by match to protein family HMM PF06808; match to protein family HMM TIGR00786 YP_001465055.1 identified by match to protein family HMM PF03480; match to protein family HMM TIGR00787 YP_001465056.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782 YP_001465057.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate YP_001465058.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate YP_001465059.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_001465060.1 identified by match to protein family HMM PF06629; match to protein family HMM TIGR03304 YP_001465061.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001465062.1 identified by match to protein family HMM PF00529 YP_001465063.1 identified by similarity to GB:AAF95962.1 YP_001465064.1 identified by glimmer YP_001465065.1 identified by similarity to SP:P37685; match to protein family HMM PF00171 YP_001465066.1 identified by match to protein family HMM PF00465 YP_001465067.1 identified by similarity to SP:P14081; match to protein family HMM PF00009; match to protein family HMM PF03144; match to protein family HMM PF09106; match to protein family HMM PF09107; match to protein family HMM TIGR00475 YP_001465068.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_001465069.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_001465070.1 identified by glimmer YP_001465071.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643 YP_001465072.1 identified by match to protein family HMM PF03130 YP_001465073.1 identified by match to protein family HMM PF03527 YP_001465074.1 identified by match to protein family HMM PF00529 YP_001465075.1 identified by similarity to GB:AAN82851.1 YP_001465076.1 identified by glimmer YP_001465077.1 identified by match to protein family HMM PF00359; match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851 YP_001465078.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_001465079.1 Acts as a repressor of the mtlAD operon YP_001465080.1 identified by similarity to RF:NP_462588.1 YP_001465081.1 identified by glimmer YP_001465083.1 identified by glimmer YP_001465085.1 identified by match to protein family HMM PF03895; match to protein family HMM PF05658; match to protein family HMM PF05662 YP_001465086.1 identified by match to protein family HMM PF02652; match to protein family HMM TIGR00795 YP_001465087.1 represses the lctPRD operon YP_001465088.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration YP_001465089.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates YP_001465090.1 catalyzes the O-acetylation of serine YP_001465091.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001465092.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_001465093.1 identified by similarity to SP:P0AC62; match to protein family HMM PF00462; match to protein family HMM TIGR02181 YP_001465094.1 identified by match to protein family HMM PF00581 YP_001465095.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_001465096.2 identified by match to protein family HMM PF01551 YP_001465097.1 identified by match to protein family HMM PF04748 YP_001465098.1 identified by match to protein family HMM PF00535 YP_001465099.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_001465100.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_001465101.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose YP_001465102.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core YP_001465103.1 identified by match to protein family HMM PF01075; match to protein family HMM TIGR02193 YP_001465104.1 identified by match to protein family HMM PF04932 YP_001465105.1 identified by match to protein family HMM PF00535 YP_001465106.1 identified by similarity to GB:AAC69673.1; match to protein family HMM PF01501; match to protein family HMM PF08437 YP_001465107.1 identified by similarity to SP:P27240; match to protein family HMM PF06176 YP_001465108.1 identified by similarity to SP:P27129; match to protein family HMM PF01501; match to protein family HMM PF08437 YP_001465109.1 identified by match to protein family HMM PF01501; match to protein family HMM PF08437 YP_001465110.1 identified by match to protein family HMM PF06293 YP_001465111.1 identified by similarity to SP:P25740; match to protein family HMM PF00534 YP_001465112.1 identified by similarity to SP:P25742; match to protein family HMM PF01075; match to protein family HMM TIGR02201 YP_001465113.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_001465114.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001465115.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001465116.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001465117.1 required for 70S ribosome assembly YP_001465118.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_001465119.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_001465120.1 catalyzes the formation of dUMP from dUTP YP_001465121.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_001465122.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001465123.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001465124.1 identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255 YP_001465125.1 identified by glimmer YP_001465126.1 identified by similarity to SP:P23840 YP_001465127.1 identified by match to protein family HMM PF03458 YP_001465128.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ YP_001465129.1 Essential for recycling GMP and indirectly, cGMP YP_001465130.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001465131.1 identified by similarity to SP:P17580; match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691 YP_001465132.1 specifically modifies tRNA at position G18 YP_001465133.1 catalyzes branch migration in Holliday junction intermediates YP_001465134.1 identified by similarity to GB:AAG58797.1 YP_001465135.1 identified by similarity to SP:P0AER8; match to protein family HMM PF03616; match to protein family HMM TIGR00210 YP_001465136.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801 YP_001465137.1 identified by match to protein family HMM PF05170 YP_001465138.1 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides YP_001465139.1 identified by glimmer YP_001465140.1 may be involved in the transport of galactosides-pentoses-hexuronides YP_001465141.1 identified by glimmer YP_001465142.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00899 YP_001465143.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950 YP_001465144.1 identified by similarity to SP:P04846; match to protein family HMM PF03180; match to protein family HMM TIGR00363 YP_001465145.1 identified by similarity to SP:Q5PC60 YP_001465146.1 experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS YP_001465147.1 identified by match to protein family HMM PF06711 YP_001465148.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_001465149.1 catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type YP_001465150.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate YP_001465151.1 membrane protein regulates uhpT expression YP_001465152.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph YP_001465153.1 identified by glimmer YP_001465154.1 response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter YP_001465155.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit YP_001465156.1 identified by similarity to SP:P08142; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118 YP_001465157.1 multidrug efflux protein involved in adaptation to low energy shock YP_001465160.1 identified by match to protein family HMM PF02656 YP_001465161.1 identified by similarity to SP:P31446 YP_001465162.1 identified by match to protein family HMM PF00884 YP_001465163.1 uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function YP_001465164.1 identified by match to protein family HMM PF00165 YP_001465165.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00852; match to protein family HMM TIGR02005 YP_001465166.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_001465167.1 identified by match to protein family HMM PF02080; match to protein family HMM PF06826; match to protein family HMM TIGR01625 YP_001465168.1 identified by glimmer YP_001465169.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent YP_001465170.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress YP_001465171.1 identified by glimmer YP_001465172.1 identified by match to protein family HMM PF07119 YP_001465173.1 identified by similarity to GB:ABB64081.1 YP_001465174.1 FAD/NAD(P)-binding domain YP_001465175.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00881; match to protein family HMM TIGR00893 YP_001465176.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_001465177.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism YP_001465178.1 identified by match to protein family HMM PF05035 YP_001465179.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_001465181.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins YP_001465182.1 yidB; identified by match to protein family HMM PF06078 YP_001465183.1 identified by glimmer YP_001465184.1 negatively supercoils closed circular double-stranded DNA YP_001465185.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001465186.1 binds the polymerase to DNA and acts as a sliding clamp YP_001465187.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001465188.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_001465189.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_001465190.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_001465191.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001465192.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan YP_001465193.1 tryptophan transporter of low affinity YP_001465194.1 Confers resistance to chloramphenicol YP_001465195.1 Involved in anaerobic NO protection YP_001465196.1 identified by similarity to GB:AAP19005.1 YP_001465197.1 identified by match to protein family HMM PF03358 YP_001465198.1 identified by match to protein family HMM PF00860 YP_001465199.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily YP_001465200.1 might be involved in hypersensitivity to nitrofurzone YP_001465201.1 identified by similarity to SP:P31469; match to protein family HMM PF03691 YP_001465202.1 identified by match to protein family HMM PF01182 YP_001465203.1 identified by match to protein family HMM PF00756; match to protein family HMM PF02922 YP_001465204.1 identified by similarity to SP:P26218; match to protein family HMM PF02264 YP_001465205.1 identified by match to protein family HMM PF00232 YP_001465206.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001465207.1 identified by glimmer YP_001465208.1 positive regulator of the beta-glucoside operon; transcriptional antiterminator YP_001465209.1 identified by glimmer YP_001465210.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_001465211.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001465212.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_001465213.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_001465214.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00975 YP_001465215.1 identified by match to protein family HMM PF00419 YP_001465216.1 identified by similarity to SP:P30130; match to protein family HMM PF00577 YP_001465217.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001465218.1 identified by match to protein family HMM PF00419 YP_001465219.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001465220.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_001465221.1 identified by glimmer YP_001465222.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001465223.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001465224.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001465225.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001465226.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001465227.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001465228.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001465229.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001465230.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation YP_001465231.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001465232.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001465233.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_001465234.1 catalyzes the formation of asparagine from aspartate and ammonia YP_001465235.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA YP_001465236.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase YP_001465237.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH YP_001465238.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_001465239.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain YP_001465240.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B YP_001465241.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system YP_001465242.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_001465243.1 DNA-binding transcriptional repressor of ribose metabolism YP_001465244.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_001465245.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_001465246.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon YP_001465247.1 identified by similarity to GB:AAZ90461.1; match to protein family HMM PF04219 YP_001465248.1 among the AAA+ ATPases, the YifB protease belongs to the Helix 2 insert clade; unknown function YP_001465249.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_001465250.1 identified by similarity to SP:P0ADG3 YP_001465251.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001465252.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001465253.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_001465254.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_001465255.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001465256.1 identified by match to protein family HMM PF00639 YP_001465257.1 identified by similarity to GB:BAC41601.1 YP_001465258.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication YP_001465259.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation YP_001465260.1 identified by glimmer YP_001465261.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_001465262.1 identified by similarity to SP:P0AA25; match to protein family HMM PF00085; match to protein family HMM TIGR01068 YP_001465263.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001465264.1 identified by glimmer YP_001465265.1 identified by match to protein family HMM PF00953; match to protein family HMM TIGR02380 YP_001465266.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein YP_001465267.1 identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236 YP_001465268.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid YP_001465269.1 identified by similarity to SP:P27830; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181 YP_001465270.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207 YP_001465271.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR02382 YP_001465272.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis YP_001465274.1 identified by glimmer YP_001465275.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis YP_001465276.1 enterobacterial common antigen polymerase YP_001465277.1 identified by match to protein family HMM PF03808; match to protein family HMM TIGR00696 YP_001465278.1 identified by glimmer YP_001465279.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function YP_001465280.1 ydeM; identified by similarity to SP:P25550; match to protein family HMM PF04055 YP_001465282.1 identified by glimmer YP_001465283.1 identified by match to protein family HMM PF07219; match to protein family HMM PF07719; match to protein family HMM TIGR00540 YP_001465284.1 identified by match to protein family HMM PF04375 YP_001465285.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis YP_001465286.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001465287.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_001465288.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly YP_001465291.1 identified by glimmer YP_001465293.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001465294.1 identified by match to protein family HMM PF04340 YP_001465295.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001465296.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function YP_001465297.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_001465299.1 identified by glimmer YP_001465300.1 responsible for the influx of magnesium ions YP_001465301.1 identified by glimmer YP_001465302.1 identified by match to protein family HMM PF06092 YP_001465303.1 identified by match to protein family HMM TIGR03034 YP_001465304.1 identified by glimmer YP_001465305.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00688 YP_001465306.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_001465307.1 catalyzes the hydrolysis of phosphatidylcholine YP_001465308.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway YP_001465309.1 identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949 YP_001465310.1 identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949 YP_001465311.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates YP_001465312.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium YP_001465313.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950 YP_001465314.1 identified by similarity to SP:P0A9F9; match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001465315.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_001465316.1 identified by match to protein family HMM PF01738 YP_001465317.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_001465318.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner YP_001465319.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_001465320.1 identified by match to protein family HMM PF06843 YP_001465321.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions YP_001465322.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001465323.1 mediates the export of protein precursors bearing twin-arginine signal peptides YP_001465324.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane YP_001465325.1 magnesium dependent; not involved in the Sec-independent protein export system YP_001465326.1 identified by similarity to SP:P26614; match to protein family HMM PF02357; match to protein family HMM TIGR01955 YP_001465327.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol YP_001465328.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_001465329.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001465330.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001465331.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_001465332.1 identified by match to protein family HMM PF01205; match to protein family HMM PF09186; match to protein family HMM TIGR00257 YP_001465333.1 identified by match to protein family HMM PF02386; match to protein family HMM TIGR00933 YP_001465334.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX YP_001465335.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway YP_001465336.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_001465337.1 identified by glimmer YP_001465338.1 identified by match to protein family HMM PF06288 YP_001465339.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_001465340.1 identified by similarity to SP:P52235; match to protein family HMM PF01323 YP_001465341.1 yihF; identified by match to protein family HMM PF06097 YP_001465342.1 identified by match to protein family HMM PF01553 YP_001465343.1 identified by glimmer YP_001465344.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_001465345.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001465346.1 identified by similarity to SP:Q8FBG9; match to protein family HMM PF04220 YP_001465347.1 identified by glimmer YP_001465348.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001465349.1 identified by glimmer YP_001465350.1 identified by glimmer YP_001465351.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54 YP_001465352.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation YP_001465353.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_001465354.1 identified by glimmer YP_001465355.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394 YP_001465356.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_001465357.1 identified by match to protein family HMM PF01261 YP_001465358.1 identified by match to protein family HMM PF07690 YP_001465359.1 porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown YP_001465360.1 identified by match to protein family HMM TIGR00792 YP_001465361.1 identified by match to protein family HMM TIGR00792 YP_001465362.1 identified by match to protein family HMM PF01055 YP_001465363.1 identified by match to protein family HMM PF01263 YP_001465364.1 identified by match to protein family HMM PF07221 YP_001465365.1 identified by match to protein family HMM PF01791 YP_001465366.1 identified by match to protein family HMM PF03446 YP_001465367.1 identified by match to protein family HMM PF00294 YP_001465368.1 identified by match to protein family HMM PF00455; match to protein family HMM PF01022; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_001465369.1 identified by similarity to SP:P0A8Y4; match to protein family HMM PF00702; match to protein family HMM TIGR01509 YP_001465370.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_001465371.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_001465372.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR02447 YP_001465373.1 identified by match to protein family HMM PF07859 YP_001465374.1 identified by glimmer YP_001465375.1 identified by similarity to GB:AAN83266.1 YP_001465376.1 identified by match to protein family HMM PF01381 YP_001465377.1 identified by glimmer YP_001465379.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001465380.1 required for the formation of active formate dehydrogenase YP_001465381.1 cytochrome b556(FDO) component; heme containing YP_001465382.1 identified by similarity to SP:P0AAJ5; match to protein family HMM PF00037; match to protein family HMM PF09163; match to protein family HMM TIGR01582 YP_001465383.1 identified by glimmer YP_001465384.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_001465386.1 repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system YP_001465387.1 with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars YP_001465388.1 identified by match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR01427 YP_001465389.1 with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system YP_001465390.1 identified by glimmer YP_001465391.1 identified by match to protein family HMM PF05336; match to protein family HMM TIGR02625 YP_001465392.1 identified by similarity to SP:P32169; match to protein family HMM PF00596; match to protein family HMM TIGR02624 YP_001465393.1 catalyzes the formation of L-rhamnulose from L-rhamnose YP_001465394.1 catalyzes the ATP-dependent phosphorylation of rhamnulose YP_001465395.1 identified by glimmer YP_001465396.1 activates the expression of the rhaBAD operon and rhaT gene YP_001465397.1 activates the expression of rhaRS in response to L-rhamnose YP_001465398.1 transports L-rhamnose and L-lyxose into the cell YP_001465399.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals YP_001465401.1 identified by glimmer YP_001465402.1 transports degraded pectin products into the bacterial cell YP_001465403.1 identified by match to protein family HMM PF03473; match to protein family HMM PF03475 YP_001465404.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors YP_001465405.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system YP_001465406.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates YP_001465407.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers YP_001465408.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_001465409.1 identified by glimmer YP_001465410.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971 YP_001465411.1 identified by match to protein family HMM PF02611; match to protein family HMM TIGR00672 YP_001465412.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001465413.1 identified by match to protein family HMM PF07305 YP_001465414.1 identified by match to protein family HMM PF05656 YP_001465415.1 identified by match to protein family HMM PF04175; match to protein family HMM TIGR00743 YP_001465416.1 with UspC and Usp E is involved in resistance to UV radiation YP_001465417.1 identified by similarity to SP:P28861; match to protein family HMM PF00175; match to protein family HMM PF00970 YP_001465418.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_001465419.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_001465420.1 identified by similarity to SP:P31140; match to protein family HMM PF00230; match to protein family HMM TIGR00861 YP_001465421.1 identified by glimmer YP_001465422.1 identified by match to protein family HMM PF06005 YP_001465423.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_001465424.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_001465425.1 heat shock protein involved in degradation of misfolded proteins YP_001465426.1 heat shock protein involved in degradation of misfolded proteins YP_001465427.1 identified by similarity to SP:P29131; match to protein family HMM PF05036; match to protein family HMM TIGR02223 YP_001465428.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins YP_001465429.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_001465430.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001465431.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643 YP_001465433.1 member of the NlpC/P60 superfamily of peptidases YP_001465434.1 identified by glimmer YP_001465435.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001465436.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_001465437.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine YP_001465438.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001465439.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_001465440.1 identified by similarity to SP:P13029; match to protein family HMM PF00141; match to protein family HMM TIGR00198 YP_001465441.1 identified by similarity to SP:P0ABT8; match to protein family HMM PF00892 YP_001465442.1 identified by similarity to GB:AAZ90633.1; match to protein family HMM PF06940 YP_001465443.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone YP_001465444.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies YP_001465445.1 identified by similarity to SP:P32670; match to protein family HMM PF00359; match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417 YP_001465446.1 FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site YP_001465447.1 FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS YP_001465448.1 involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein YP_001465449.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494 YP_001465450.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog YP_001465451.1 identified by match to protein family HMM PF00165 YP_001465452.1 identified by match to protein family HMM PF00884 YP_001465453.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_001465454.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_001465455.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001465456.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001465457.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001465458.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_001465459.1 identified by match to protein family HMM PF07690 YP_001465460.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA YP_001465461.1 catalyzes the conversion of NADPH to NADH YP_001465462.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_001465463.1 identified by match to protein family HMM PF07226 YP_001465464.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_001465465.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space YP_001465466.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001465467.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001465468.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_001465469.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_001465470.1 identified by glimmer YP_001465471.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001465472.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001465473.1 Modulates Rho-dependent transcription termination YP_001465474.1 identified by similarity to GB:AAN83366.1 YP_001465475.1 binds directly to 23S ribosomal RNA YP_001465476.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001465477.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001465478.1 identified by glimmer YP_001465479.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001465480.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001465481.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001465482.1 identified by similarity to SP:P27375 YP_001465483.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_001465484.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_001465485.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate YP_001465486.1 identified by similarity to SP:P30138; match to protein family HMM PF00899; match to protein family HMM PF05237; match to protein family HMM TIGR02356 YP_001465487.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate YP_001465488.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001465489.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_001465490.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates YP_001465491.1 identified by glimmer YP_001465492.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001465493.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures YP_001465494.1 identified by match to protein family HMM PF04222 YP_001465495.1 histone-like DNA-binding protein YP_001465496.1 identified by match to protein family HMM PF07356 YP_001465497.1 identified by similarity to SP:P0AAA9 YP_001465498.1 identified by glimmer YP_001465499.1 identified by similarity to SP:P14377; match to protein family HMM PF00512; match to protein family HMM PF02518 YP_001465500.1 DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein YP_001465501.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001465502.1 involved in de novo purine biosynthesis YP_001465503.1 identified by glimmer YP_001465504.1 identified by match to protein family HMM PF00583 YP_001465505.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_001465506.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_001465507.1 identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346 YP_001465508.1 identified by glimmer YP_001465509.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol YP_001465510.1 identified by match to protein family HMM PF07906 YP_001465511.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase YP_001465512.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_001465513.1 identified by match to protein family HMM PF02690; match to protein family HMM TIGR00704; match to protein family HMM TIGR01013 YP_001465514.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family YP_001465515.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA YP_001465516.1 identified by similarity to GB:AAZ90700.1 YP_001465517.1 identified by glimmer YP_001465518.1 identified by match to protein family HMM PF01145 YP_001465519.1 identified by similarity to GB:CAD13753.1 YP_001465520.1 identified by match to protein family HMM PF06414 YP_001465521.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_001465522.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001465525.1 identified by match to protein family HMM PF06251 YP_001465526.1 identified by match to protein family HMM PF06082 YP_001465527.1 identified by glimmer YP_001465528.1 identified by similarity to GB:ABB68492.1 YP_001465529.1 identified by glimmer YP_001465530.1 identified by match to protein family HMM PF06146 YP_001465531.1 xylose/proton symporter; member of the major facilitator superfamily (MFS) of transporter YP_001465532.1 with MalKFE is involved in the transport of maltose into the cell YP_001465533.1 with MalKGE is involved in maltose transport into the cell YP_001465534.1 identified by glimmer YP_001465535.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis YP_001465536.1 with malEFG is involved in import of maltose/maltodextrin YP_001465537.1 porin involved in the transport of maltose and maltodextrins YP_001465538.1 identified by match to protein family HMM PF07148 YP_001465539.1 identified by glimmer YP_001465540.1 catalyzes the formation of 4-hydroxybenzoate from chorismate YP_001465541.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_001465542.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_001465543.1 identified by similarity to SP:P0ABN1; match to protein family HMM PF01219 YP_001465544.1 Represses a number of genes involved in the response to DNA damage YP_001465545.1 identified by similarity to SP:P28303; match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_001465546.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential YP_001465547.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB YP_001465549.1 identified by similarity to SP:P32695; match to protein family HMM PF01207; match to protein family HMM TIGR00742 YP_001465550.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia YP_001465551.1 identified by similarity to SP:P28304; match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001465552.1 unwinds double stranded DNA YP_001465553.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_001465554.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001465555.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity YP_001465556.1 identified by match to protein family HMM PF01894; match to protein family HMM TIGR00149 YP_001465557.1 identified by match to protein family HMM PF04237 YP_001465558.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_001465559.1 binds to single stranded DNA and PriA helcase facilitate replication restart YP_001465560.1 identified by glimmer YP_001465562.1 identified by match to protein family HMM PF00563 YP_001465563.1 regulates genes involved in response to oxidative stress YP_001465564.1 identified by match to protein family HMM PF00376; match to protein family HMM PF09278; match to protein family HMM TIGR01950 YP_001465565.1 identified by glimmer YP_001465566.1 identified by glimmer YP_001465567.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_001465568.1 identified by match to protein family HMM PF00999; match to protein family HMM TIGR00831 YP_001465569.1 identified by match to protein family HMM PF00805 YP_001465570.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake YP_001465571.1 identified by match to protein family HMM PF04341 YP_001465572.1 identified by glimmer YP_001465573.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001465574.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552 YP_001465575.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia YP_001465576.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR01409; match to protein family HMM TIGR03149 YP_001465577.1 identified by match to protein family HMM PF03916; match to protein family HMM TIGR03148 YP_001465578.1 with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552 YP_001465579.1 identified by similarity to SP:P32711; match to protein family HMM PF03918; match to protein family HMM TIGR03147 YP_001465580.1 identified by similarity to SP:P32712; match to protein family HMM PF00515; match to protein family HMM PF07719 YP_001465581.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system YP_001465582.1 identified by match to protein family HMM PF08238 YP_001465583.1 identified by similarity to SP:P07658; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01591 YP_001465584.1 part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family YP_001465585.1 possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_001465586.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_001465588.1 identified by match to protein family HMM PF00753 YP_001465589.1 identified by glimmer YP_001465590.1 identified by similarity to GB:AAZ90762.1 YP_001465591.1 required for the use of phosphonates and phosphite as phosphorus sources YP_001465592.1 PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role YP_001465593.1 identified by match to protein family HMM TIGR02322 YP_001465594.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR02318 YP_001465595.1 identified by similarity to SP:P16679; match to protein family HMM PF00005; match to protein family HMM TIGR02324 YP_001465596.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02323 YP_001465597.1 identified by match to protein family HMM PF06007 YP_001465598.1 identified by match to protein family HMM PF05861 YP_001465599.1 identified by match to protein family HMM PF05845 YP_001465600.1 identified by match to protein family HMM PF06754; match to protein family HMM TIGR03293 YP_001465601.1 may be involved in phosphonate uptake and biodegradation YP_001465602.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01097 YP_001465603.1 identified by match to protein family HMM TIGR01098; match to protein family HMM TIGR03431 YP_001465604.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR02315 YP_001465605.1 identified by glimmer YP_001465606.1 identified by similarity to SP:P16681; match to protein family HMM PF00903 YP_001465607.1 identified by match to protein family HMM PF03831; match to protein family HMM PF08274; match to protein family HMM TIGR00686 YP_001465610.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM PF08946; match to protein family HMM TIGR00883 YP_001465611.1 identified by similarity to SP:P30844; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_001465612.1 response regulator in two-component regulatory system with BasS YP_001465613.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division YP_001465614.1 identified by similarity to SP:P60061; match to protein family HMM PF00324 YP_001465615.1 identified by similarity to GB:AAB18143.1; match to protein family HMM PF00165 YP_001465616.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_001465617.1 identified by similarity to SP:P0ACH8; match to protein family HMM PF00165 YP_001465618.1 identified by similarity to SP:P06720; match to protein family HMM PF02056 YP_001465619.1 identified by similarity to SP:P02921; match to protein family HMM TIGR00792 YP_001465621.1 identified by similarity to SP:P14407; match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723 YP_001465622.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration YP_001465623.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration YP_001465624.1 identified by match to protein family HMM PF06902 YP_001465626.1 identified by glimmer YP_001465627.1 identified by similarity to GB:AAV77221.1 YP_001465628.1 class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001465629.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924 YP_001465630.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_001465631.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein YP_001465632.1 regulates the cadBA operon YP_001465633.1 identified by match to protein family HMM PF00440 YP_001465634.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_001465635.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals YP_001465636.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_001465637.1 catalyzes the formation of fumarate from aspartate YP_001465638.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein YP_001465639.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function YP_001465640.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001465641.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001465643.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001465645.1 identified by glimmer YP_001465646.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR00238 YP_001465647.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001465648.1 acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex YP_001465649.1 identified by glimmer YP_001465650.1 member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations YP_001465651.1 lipocalin; globomycin-sensitive outer membrane lipoprotein YP_001465652.1 identified by match to protein family HMM PF00144 YP_001465653.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane YP_001465654.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001465655.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001465656.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001465657.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001465658.1 identified by match to protein family HMM PF00324 YP_001465659.1 identified by match to protein family HMM PF00924 YP_001465660.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_001465661.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_001465662.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_001465663.1 identified by match to protein family HMM PF00037; match to protein family HMM PF08331; match to protein family HMM TIGR00276 YP_001465664.1 identified by match to protein family HMM PF01256; match to protein family HMM PF03853; match to protein family HMM TIGR00196; match to protein family HMM TIGR00197 YP_001465665.1 possibly involved in cell wall synthesis YP_001465666.1 identified by match to protein family HMM PF01520 YP_001465667.1 identified by glimmer YP_001465668.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001465669.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001465670.1 Stimulates the elongation of poly(A) tails YP_001465671.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein YP_001465672.1 with HflC inhibits proteolysis of lambda cII protein by FtsH YP_001465673.1 with HflK inhibits proteolysis of lambda cII protein by FtsH YP_001465675.1 identified by glimmer YP_001465676.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001465677.1 negatively regulates the transcription of genes upregulated by nitrosative stress YP_001465678.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs YP_001465679.1 identified by glimmer YP_001465680.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_001465681.1 identified by similarity to GB:CAD06847.1 YP_001465682.1 identified by match to protein family HMM PF04012 YP_001465684.1 identified by match to protein family HMM PF03994 YP_001465685.1 identified by match to protein family HMM PF06693 YP_001465686.1 identified by match to protein family HMM PF03738 YP_001465687.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA YP_001465688.1 identified by match to protein family HMM PF07338 YP_001465689.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility YP_001465690.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo YP_001465691.1 negative regulator of ulaG and ulaABCDEF YP_001465692.1 identified by similarity to SP:P39300 YP_001465693.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_001465694.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001465695.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization YP_001465696.1 identified by glimmer YP_001465697.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway YP_001465698.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_001465699.1 identified by match to protein family HMM PF07338 YP_001465700.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001465701.1 binds single-stranded DNA at the primosome assembly site YP_001465702.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001465703.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001465704.1 identified by match to protein family HMM PF03480; match to protein family HMM TIGR00787 YP_001465705.1 identified by match to protein family HMM PF06808; match to protein family HMM TIGR00786 YP_001465706.1 identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF07992 YP_001465707.1 identified by match to protein family HMM PF01144 YP_001465708.1 identified by glimmer YP_001465709.1 identified by match to protein family HMM PF00378 YP_001465710.1 identified by match to protein family HMM PF01261 YP_001465711.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001465712.1 identified by match to protein family HMM PF00440 YP_001465713.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides YP_001465714.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine YP_001465715.1 identified by glimmer YP_001465716.1 Involved in anaerobic NO protection and iron metabolism YP_001465717.1 identified by similarity to SP:P39314; match to protein family HMM PF00892 YP_001465718.1 identified by glimmer YP_001465719.1 identified by match to protein family HMM PF01073; match to protein family HMM PF05368 YP_001465720.1 identified by match to protein family HMM PF01638 YP_001465721.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_001465722.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate YP_001465723.1 identified by match to protein family HMM TIGR01626 YP_001465724.1 identified by match to protein family HMM PF06526 YP_001465725.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_001465726.1 identified by glimmer YP_001465727.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_001465728.1 identified by match to protein family HMM PF01103; match to protein family HMM PF07244 YP_001465729.1 identified by match to protein family HMM PF04357 YP_001465730.1 identified by match to protein family HMM PF03674 YP_001465731.1 part of the toxin-antitoxin ChpB-ChpS system YP_001465732.1 toxin of the ChpB-ChpS toxin-antitoxin system YP_001465733.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001465734.1 identified by similarity to GB:AAN83745.1 YP_001465735.1 identified by match to protein family HMM PF00532 YP_001465736.1 identified by match to protein family HMM PF00005 YP_001465737.1 identified by match to protein family HMM PF02653 YP_001465738.1 membrane component of a sugar ABC transporter system YP_001465739.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_001465741.1 identified by similarity to SP:P37773; match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01081 YP_001465742.1 identified by match to protein family HMM PF04751 YP_001465743.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD YP_001465744.1 identified by similarity to SP:P0ABE7; match to protein family HMM PF07361 YP_001465745.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions YP_001465746.1 identified by glimmer YP_001465747.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_001465748.1 identified by similarity to GB:CAD06913.1 YP_001465749.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403 YP_001465750.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001465751.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon YP_001465752.1 P-type ATPase involved in magnesium influx YP_001465753.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001465754.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004 YP_001465755.1 involved in the allosteric regulation of aspartate carbamoyltransferase YP_001465756.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001465757.1 identified by glimmer YP_001465758.1 identified by match to protein family HMM PF01042 YP_001465759.1 identified by match to protein family HMM PF00106 YP_001465760.1 identified by match to protein family HMM PF00440 YP_001465761.1 identified by similarity to SP:P0AF97; match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_001465762.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III. YP_001465763.1 identified by similarity to PDB:1NXI_A; match to protein family HMM PF06877 YP_001465764.1 identified by match to protein family HMM PF00583 YP_001465765.1 identified by match to protein family HMM PF05987 YP_001465766.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001465767.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_001465768.1 identified by glimmer YP_001465769.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001465770.1 identified by match to protein family HMM PF03739 YP_001465771.1 identified by match to protein family HMM PF03739 YP_001465772.1 identified by match to protein family HMM PF05872 YP_001465773.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001465774.1 identified by glimmer YP_001465775.1 identified by match to protein family HMM PF00078; match to protein family HMM PF08388 YP_001465776.1 identified by match to protein family HMM PF01527 YP_001465777.1 identified by match to protein family HMM PF01695 YP_001465778.1 identified by match to protein family HMM PF00440; match to protein family HMM PF02178 YP_001465779.1 identified by match to protein family HMM PF01527 YP_001465780.1 identified by similarity to SP:P05822; match to protein family HMM PF00665 YP_001465781.1 identified by glimmer YP_001465782.1 identified by similarity to GB:AAN68935.1 YP_001465783.1 identified by match to protein family HMM PF02028; match to protein family HMM TIGR00842 YP_001465784.1 Note that the 2 orfs of the ISSd1 transposase appear to be fused in this version of the element.; identified by match to protein family HMM PF00665; match to protein family HMM PF01527 YP_001465785.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_001465786.1 identified by match to protein family HMM PF04393 YP_001465787.1 identified by match to protein family HMM PF00534 YP_001465788.1 identified by match to protein family HMM PF01522 YP_001465789.1 identified by match to protein family HMM PF01527 YP_001465790.1 identified by match to protein family HMM PF00078; match to protein family HMM PF08388 YP_001465791.1 identified by match to protein family HMM PF03050 YP_001465792.1 identified by match to protein family HMM PF05717 YP_001465793.1 identified by match to protein family HMM PF01527 YP_001465794.1 identified by similarity to GB:CAG75835.1 YP_001465795.1 Part of the FecBCDE citrate-dependent iron (III) transport system YP_001465796.1 Ferric citrate binds FecA and is transported across the outer membrane while transmits a signal across the cytoplasmic membrane protein FecR. FecR transmits a signal across the membrane and activates the cytoplasmic FecI that directs the RNA polymerase to express the fecABCDE operon (which encodes the ferric citrate outer membrane receptor and the ferric citrate ABC transporter), as well as fecIR. FecD is one of two (along with FecC) integral membrane protein components of the iron dicitrate ABC transporter. YP_001465797.1 part of the FecBCDE citrate-dependent iron (III) transport system YP_001465798.1 part of the ABC transporter involved in the uptake of citrate-dependent Fe(3+) YP_001465799.1 identified by similarity to SP:P13036; match to protein family HMM PF00593; match to protein family HMM PF07660; match to protein family HMM PF07715; match to protein family HMM TIGR01783 YP_001465800.1 with FecA forms the FecAR signal transduction system; ferric citrate binds FecA and transmits a signal across the outer membrane to FecR. FecR transmits a signal across the cytoplasmic membrane and activates the sigma 70 protein FecI that directs the RNA polymerase to express the fecABCDE operon YP_001465801.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor regulates the genes for iron dicitrate transport YP_001465802.1 identified by match to protein family HMM PF03811 YP_001465803.1 identified by glimmer YP_001465805.1 identified by glimmer YP_001465806.1 identified by glimmer YP_001465807.1 identified by match to protein family HMM PF05717 YP_001465808.1 identified by match to protein family HMM PF03050 YP_001465809.1 identified by match to protein family HMM PF05717 YP_001465810.1 identified by match to protein family HMM PF01527 YP_001465811.1 identified by similarity to GB:ABB64202.1 YP_001465812.1 identified by glimmer YP_001465814.1 identified by match to protein family HMM PF05321 YP_001465815.1 identified by match to protein family HMM PF05930 YP_001465816.1 identified by similarity to GB:AAL08467.1 YP_001465817.1 identified by glimmer YP_001465818.1 identified by similarity to GB:AAL08470.1 YP_001465819.1 identified by match to protein family HMM PF01926 YP_001465820.1 identified by similarity to SP:P39180; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414 YP_001465821.1 identified by similarity to GB:AAS76399.1 YP_001465822.1 identified by similarity to GB:ABB61180.1; match to protein family HMM PF06067 YP_001465823.1 identified by match to protein family HMM PF03230 YP_001465824.1 identified by match to protein family HMM PF04002; match to protein family HMM TIGR00608 YP_001465825.1 identified by similarity to GB:AAP18295.1; match to protein family HMM PF06174 YP_001465826.1 identified by similarity to GB:ABB61176.1 YP_001465827.1 identified by similarity to GB:ABB61175.1; match to protein family HMM PF06154 YP_001465828.1 identified by match to protein family HMM PF06755 YP_001465829.1 identified by similarity to GB:ABB64452.1 YP_001465830.1 identified by similarity to GB:ABB61172.1; match to protein family HMM PF06117 YP_001465831.1 identified by match to protein family HMM PF00176; match to protein family HMM PF00271; match to protein family HMM PF04851 YP_001465832.1 identified by match to protein family HMM PF01555 YP_001465833.1 identified by glimmer YP_001465835.1 identified by glimmer YP_001465836.1 identified by match to protein family HMM PF03629 YP_001465837.1 identified by match to protein family HMM PF01344; match to protein family HMM PF07646 YP_001465838.1 identified by match to protein family HMM PF06178 YP_001465839.1 identified by glimmer YP_001465840.1 identified by match to protein family HMM PF03811 YP_001465841.1 identified by match to protein family HMM PF03400 YP_001465842.1 identified by similarity to SP:P30130; match to protein family HMM PF00577 YP_001465843.1 identified by similarity to SP:P08189; match to protein family HMM PF00419 YP_001465844.1 identified by similarity to SP:P08190; match to protein family HMM PF00419 YP_001465845.1 identified by match to protein family HMM PF00419; match to protein family HMM PF09160 YP_001465846.1 identified by glimmer YP_001465847.1 identified by similarity to SP:P0AC94; match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_001465848.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_001465849.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_001465850.1 identified by glimmer YP_001465851.1 regulates the expression of uxuBA YP_001465852.1 identified by glimmer YP_001465853.1 inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS YP_001465854.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001465855.1 identified by similarity to SP:P39377; match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR01975 YP_001465856.1 identified by match to protein family HMM PF07670 YP_001465857.1 identified by match to protein family HMM PF07670 YP_001465858.1 identified by glimmer YP_001465859.1 in yeast cells this enzyme removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate; functions in tRNA splicing; the function and substrate of bacterial enzymes in organisms that do not perform splicing is unknown YP_001465860.1 identified by match to protein family HMM PF06779; match to protein family HMM PF07690 YP_001465861.1 identified by match to protein family HMM PF06977 YP_001465863.1 identified by similarity to SP:P11568; match to protein family HMM PF01869; match to protein family HMM TIGR00241 YP_001465864.1 identified by match to protein family HMM PF06050 YP_001465865.1 identified by match to protein family HMM PF04286 YP_001465866.1 identified by match to protein family HMM PF07690 YP_001465867.1 identified by match to protein family HMM PF03811 YP_001465868.1 identified by similarity to GB:BAB72712.1; match to protein family HMM PF04365 YP_001465869.1 identified by similarity to GB:AAV80076.1 YP_001465870.1 identified by match to protein family HMM PF02492; match to protein family HMM PF07683 YP_001465871.1 identified by similarity to SP:P0ADD1; match to protein family HMM PF04328 YP_001465872.1 identified by match to protein family HMM PF02554 YP_001465873.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203 YP_001465874.1 identified by match to protein family HMM PF07690 YP_001465875.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_001465876.1 identified by glimmer YP_001465877.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001465878.1 catalyzes the transfer of phosphoglycerol to the glucan backbone YP_001465880.1 acts to load the DnaB helicase onto the initiation site during DNA replication YP_001465881.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' YP_001465883.1 identified by match to protein family HMM PF06738 YP_001465884.1 identified by glimmer YP_001465885.1 identified by match to protein family HMM PF00196 YP_001465886.1 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin YP_001465887.1 identified by similarity to SP:P39405; match to protein family HMM PF06276 YP_001465888.1 identified by similarity to GB:AAN83867.1; match to protein family HMM PF07256 YP_001465889.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit YP_001465890.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_001465891.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18 YP_001465892.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily YP_001465893.1 identified by glimmer YP_001465894.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_001465895.1 identified by glimmer YP_001465896.1 identified by similarity to SP:P27291; match to protein family HMM PF04972 YP_001465897.1 identified by glimmer YP_001465898.1 identified by match to protein family HMM PF01734 YP_001465899.1 identified by match to protein family HMM PF01026 YP_001465900.1 identified by match to protein family HMM PF00037; match to protein family HMM PF04055 YP_001465901.1 yjjI YP_001465903.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_001465904.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_001465905.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_001465906.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_001465907.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins YP_001465909.1 catalyzes the formation of serine from O-phosphoserine YP_001465910.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001465911.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide YP_001465912.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001465913.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan YP_001465914.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription YP_001465915.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_001465916.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate YP_001465917.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445 YP_001465918.1 identified by match to protein family HMM PF05981 YP_001465919.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation YP_001465920.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation YP_001465921.1 identified by match to protein family HMM PF06123 YP_001465922.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_001465923.1 identified by similarity to GB:AAV80131.1 YP_001465924.1 member of the SPOUT superfamily of methyltransferases