-- dump date   	20140619_082052
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
YP_002396091.1	multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways
YP_002396092.1	catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate
YP_002396093.1	catalyzes the formation of L-threonine from O-phospho-L-homoserine
YP_002396094.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396095.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396096.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396097.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8332529, 92334977, 11298760, 7592346, 8805555, 9007983, 9298646; Product type e : enzyme
YP_002396098.1	forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis
YP_002396099.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396100.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8478327; Product type r : regulator
YP_002396101.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396102.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
YP_002396103.1	chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion
YP_002396104.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396105.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396106.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396107.1	exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH
YP_002396108.1	Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC
YP_002396109.1	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase
YP_002396110.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396111.1	catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities
YP_002396112.1	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme
YP_002396113.1	lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis
YP_002396114.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 97332650, 2011499; Product type e : enzyme
YP_002396115.1	catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway
YP_002396116.1	catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides
YP_002396117.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396118.1	catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis
YP_002396119.1	catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers
YP_002396120.1	four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity
YP_002396121.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 7815937, 6308632
YP_002396122.1	regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons
YP_002396123.1	involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities
YP_002396124.2	catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA
YP_002396125.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15731894, 97189569, 7815937; Product type e : enzyme
YP_002396126.1	catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine
YP_002396127.1	catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA
YP_002396128.1	catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism
YP_002396129.1	required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase
YP_002396130.1	involved in electron transfer during carnitine metabolism
YP_002396131.1	FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction
YP_002396132.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96066354, 12081978; Product type pc : putative carrier
YP_002396133.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396134.1	Required for full activity of KefC, a potassium-proton antiporter
YP_002396135.1	transport system that facilitates potassium-efflux
YP_002396136.1	catalyzes the reduction of dihydrofolate to tetrahydrofolate
YP_002396137.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002396138.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002396139.1	hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP
YP_002396140.1	protein associated with Co2+ and Mg2+ efflux
YP_002396141.1	catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin
YP_002396142.1	catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate)
YP_002396143.1	Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB
YP_002396144.1	determines N-hexane tolerance and is involved in outer membrane permeability
YP_002396145.1	functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system
YP_002396146.1	catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs
YP_002396147.1	transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA
YP_002396148.1	Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C
YP_002396149.1	catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
YP_002396150.1	catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism
YP_002396151.1	catalyzes the phosphorylation of ribulose to ribulose 5-phosphate
YP_002396152.1	positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose
YP_002396153.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396154.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396155.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396156.1	with TbpA and ThiP is part of the thiamine and TPP transport system
YP_002396157.1	permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine
YP_002396158.1	part of the thiamine and TPP transport system tbpA-thiPQ
YP_002396159.1	activates sgrS under glucose-phosphate stress conditions
YP_002396160.1	catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D
YP_002396161.1	dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate
YP_002396162.1	catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis
YP_002396163.1	catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis
YP_002396164.1	involved in attenuation control of the leuABCD operon in leucine biosynthesis
YP_002396165.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002396166.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002396167.1	catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive
YP_002396168.1	with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit
YP_002396169.1	binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism
YP_002396170.1	MraZ; UPF0040; crystal structure shows similarity to AbrB
YP_002396171.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20042184, 10493123, 2187182, 6350821; Product type e : enzyme
YP_002396172.1	membrane bound cell division protein at septum containing leucine zipper motif
YP_002396173.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91072213, 92202178, 94095121, 9603865, 9614966, 1332942, 1447153, 2198024, 2677607, 2681146, 3049550, 3911028, 6350821; Product type e : enzyme
YP_002396174.1	involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate
YP_002396175.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88273095, 90248455, 91310568, 97128642, 11090285, 2668880, 9166795; Product type e : enzyme
YP_002396176.1	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YP_002396177.1	UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation
YP_002396178.1	integral membrane protein involved in stabilizing FstZ ring during cell division
YP_002396179.1	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
YP_002396180.1	Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis
YP_002396181.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
YP_002396182.1	involved in septum formation
YP_002396183.1	ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane
YP_002396184.1	GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function
YP_002396185.1	zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis
YP_002396186.1	secM translational pause allows for the initiation of secA translation
YP_002396187.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins
YP_002396188.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10218109, 89264540, 90136514, 91225007, 97444511, 1309939, 2841285, 3033442, 3288626, 7578113, 9063868; Product type e : enzyme
YP_002396189.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396190.1	catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis
YP_002396191.1	catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate
YP_002396192.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96099298, 2904262, 7959070; Product type s : structure
YP_002396193.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96099298, 7959070; Product type pt : putative transporter
YP_002396194.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20100782, 20271862, 96099298, 7959070; Product type ps : putative structure
YP_002396195.1	catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide
YP_002396196.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90113890, 95047240, 2607970, 7959070; Product type e : enzyme
YP_002396197.1	involved in regulation of beta-lactamase; putative signaling protein
YP_002396198.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1104763, 90174991, 9150230; Product type t : transporter
YP_002396199.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10702359
YP_002396200.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002396201.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002396202.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002396203.1	activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex
YP_002396204.1	E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC
YP_002396205.1	E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains
YP_002396206.1	E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide
YP_002396207.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396208.1	catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate
YP_002396209.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2666401, 7567469
YP_002396210.1	S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine
YP_002396211.1	catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine
YP_002396212.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2666401
YP_002396213.1	laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification
YP_002396214.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10359647, 11604400, 14612441, 91035240, 93123180, 93286127; Product type e : enzyme
YP_002396215.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 13808016, 339828, 6787390, 6801015, 12070315; Product type e : enzyme
YP_002396216.1	catalyzes the interconversion of bicarbonate and carbon dioxide
YP_002396217.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396218.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10474187; Product type pt : putative transporter
YP_002396219.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396220.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396221.1	Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5)
YP_002396222.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11319082; Product type pe : putative enzyme
YP_002396223.1	catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine
YP_002396224.1	catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate
YP_002396225.1	Evidence 2b : Function of strongly homologous gene; Product type ps : putative structure
YP_002396226.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002396227.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002396228.1	similar to the fimbrial usher protein PapC
YP_002396229.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 93352405, 8102362, 15561151; Product type f : factor
YP_002396230.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002396231.1	catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP
YP_002396232.1	Polymerase that creates the 3' poly(A) tail found in some mRNA's
YP_002396233.1	this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu
YP_002396234.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15294157, 90202727, 2013578, 9298646, 9600841; Product type r : regulator
YP_002396235.1	Regulatory factor involved in maltose metabolism
YP_002396236.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 97094878; Product type e : enzyme
YP_002396237.1	similar in sequence to the ATP-dependent RNA helicase HrpA
YP_002396238.1	bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell
YP_002396239.1	involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein
YP_002396240.1	part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter
YP_002396241.1	Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores
YP_002396242.1	part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome
YP_002396243.1	Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway
YP_002396244.1	Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation
YP_002396245.1	essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors
YP_002396246.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396247.1	solute binding component of the vitamin B12 transport system BtuCDF
YP_002396248.1	enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine
YP_002396249.1	forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate
YP_002396250.1	protease Do; required at high temperature; degrades damaged proteins
YP_002396251.1	regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization
YP_002396252.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396253.1	catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway
YP_002396254.1	catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein
YP_002396255.1	catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn
YP_002396256.1	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
YP_002396257.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
YP_002396258.1	Catalyzes the phosphorylation of UMP to UDP
YP_002396259.1	Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs
YP_002396260.1	catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate
YP_002396261.1	catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate
YP_002396262.1	catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate
YP_002396263.1	catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response
YP_002396264.1	part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins
YP_002396265.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15101556, 90201355, 97032152, 99386928, 1987124, 2843433, 9298646, 2167239; Product type f : factor
YP_002396266.1	adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis
YP_002396267.1	in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP
YP_002396268.1	catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis
YP_002396269.1	catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM
YP_002396270.1	RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids
YP_002396271.1	catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase
YP_002396272.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein
YP_002396273.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 97480927, 98195734, 98357244, 9226257, 9723924; Product type e : enzyme
YP_002396274.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396275.1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase
YP_002396276.1	Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination
YP_002396277.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396278.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396279.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396280.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11830644, 95362641, 95362642; Product type lp : lipoprotein
YP_002396281.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002396282.1	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
YP_002396283.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396284.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 93094132; Product type pr : putative regulator
YP_002396285.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12169620, 12218041, 12819857, 1459951; Product type t : transporter
YP_002396286.1	part of the MetNIQ methionine uptake system
YP_002396287.1	part of the metNIQ transport system for methionine
YP_002396288.1	Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate
YP_002396289.1	catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid
YP_002396290.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002396291.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1663890
YP_002396292.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396293.1	catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall
YP_002396294.1	catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione
YP_002396295.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396296.1	An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
YP_002396297.1	3'-5' exonuclease of DNA polymerase III
YP_002396298.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396299.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396300.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002396301.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396302.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396303.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002396304.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002396305.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396306.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396307.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396308.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396309.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396310.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396311.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396312.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396313.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396314.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396315.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396316.1	Evidence 6 : Doubtful CDS
YP_002396317.1	Evidence 5 : No homology to any previously reported sequences
YP_002396318.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396319.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396320.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396321.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396322.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396323.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396324.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396325.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396326.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8526497; Product type pe : putative enzyme
YP_002396327.1	inactivates vertebrate C-type lysozyme
YP_002396328.1	functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA
YP_002396329.1	catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate
YP_002396330.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396331.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396332.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396333.1	Evidence 7 : Gene remnant; Product type s : structure
YP_002396334.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure
YP_002396335.1	involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function
YP_002396336.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12813093, 14594833; Product type pf : putative factor
YP_002396337.1	YafO overproduction induces toxicity; it is believed to be the toxin of a toxin-antitoxin pair; unknown function
YP_002396338.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12813093; Product type pe : putative enzyme
YP_002396339.1	mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY
YP_002396340.1	similar to release factor 1 and 2
YP_002396341.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1695895, 21101837, 88121730, 92204123, 2651887; Product type e : enzyme
YP_002396342.1	catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively
YP_002396343.1	forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation
YP_002396344.1	involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS
YP_002396345.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89178658, 89380253, 92219258, 98090453, 1380671, 1848301, 1848682, 6089111, 6341601, 7679770; Product type t : transporter
YP_002396346.1	catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis
YP_002396347.1	Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway
YP_002396348.1	Evidence 5 : No homology to any previously reported sequences
YP_002396349.1	Evidence 5 : No homology to any previously reported sequences
YP_002396350.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002396351.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396352.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396353.1	Evidence 6 : Doubtful CDS
YP_002396354.1	Evidence 5 : No homology to any previously reported sequences
YP_002396355.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396356.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002396357.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002396358.1	Evidence 6 : Doubtful CDS
YP_002396359.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2820984, 88007632, 91154204, 2836810, 3543693; Product type t : transporter
YP_002396360.1	Evidence 2b : Function of strongly homologous gene; Product type t : transporter
YP_002396361.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002396362.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396363.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1339433; Product type e : enzyme
YP_002396364.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002396365.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14993306; Product type e : enzyme
YP_002396366.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1761221, 112095; Product type e : enzyme
YP_002396367.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10844662; Product type pe : putative enzyme
YP_002396368.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396369.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396370.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1310503, 1321417
YP_002396371.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396372.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1577690, 11497462; Product type pe : putative enzyme
YP_002396373.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396374.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9099855; Product type pt : putative transporter
YP_002396375.1	Evidence 7 : Gene remnant
YP_002396376.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396377.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396378.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396379.1	Evidence 5 : No homology to any previously reported sequences
YP_002396380.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396381.1	Evidence 7 : Gene remnant
YP_002396382.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15385522, 15075407; Product type e : enzyme
YP_002396383.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 5385522, 15075407, 10648508; Product type pe : putative enzyme
YP_002396384.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10648508, 15385522; Product type e : enzyme
YP_002396385.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15385522, 10648508; Product type pr : putative regulator
YP_002396386.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396387.1	RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
YP_002396388.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002396389.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002396390.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002396391.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 17563352, 11466275; Product type s : structure
YP_002396392.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396393.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396394.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396395.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396396.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396397.1	Involved in disulfide oxidoreductase activity and electron transport
YP_002396398.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002396399.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396400.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396401.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396402.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396403.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396404.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002396405.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396406.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396407.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7711027, 11523892; Product type pe : putative enzyme
YP_002396408.1	metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain
YP_002396409.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396410.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396411.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396412.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002396413.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002396414.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396415.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396416.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12879215; Product type t : transporter
YP_002396417.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396418.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9325432, 15805526; Product type r : regulator
YP_002396419.1	catalyzes the formation of pyruvate and succinate from 2-methylisocitrate
YP_002396420.1	catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity
YP_002396421.1	functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C
YP_002396422.1	catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent
YP_002396423.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92349961; Product type t : transporter
YP_002396424.1	Catalyzes the deamination of cytosine to uracil and ammonia
YP_002396425.1	transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown
YP_002396426.1	lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments
YP_002396427.1	forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon
YP_002396428.1	transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer
YP_002396429.1	activator of 3-phenylpropionic acid catabolism
YP_002396430.1	catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate
YP_002396431.1	catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family
YP_002396432.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87008429, 94002258, 15663942; Product type e : enzyme
YP_002396433.1	catalyzes the formation of 2-keto-4-hydroxypentanoic acid from 2-hydroxypentadienoic acid
YP_002396434.1	catalyzes the formation of acetyl-CoA from acetalaldehyde
YP_002396435.1	catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate
YP_002396436.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 7961399; Product type t : transporter
YP_002396437.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15115803, 12878731, 13129938; Product type e : enzyme
YP_002396438.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16567800, 15466022; Product type e : enzyme
YP_002396439.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15466022, 87172301, 1731906; Product type e : enzyme
YP_002396440.1	formaldehyde-induced negative regulator of the frmRAB operon
YP_002396441.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396442.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396443.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396444.1	with TauB and TauC is responsible for taurine uptake.
YP_002396445.1	Part of the ABC transporter complex tauABC involved in taurine import
YP_002396446.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9401024, 96404792; Product type t : transporter
YP_002396447.1	catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers
YP_002396448.1	catalyzes the formation of porphobilinogen from 5-aminolevulinate
YP_002396449.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002396450.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002396451.1	this protein has no known enzymatic function
YP_002396452.1	in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope
YP_002396453.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002396454.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396455.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396456.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
YP_002396457.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396458.1	Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme
YP_002396459.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3533724, 2160940; Product type f : factor
YP_002396460.1	catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis
YP_002396461.1	catalyzes the formation of L-proline from pyrroline-5-carboxylate
YP_002396462.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396463.1	type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis
YP_002396464.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396465.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 86085675, 3001025
YP_002396466.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396467.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396468.1	Required for efficient pilin antigenic variation
YP_002396469.1	catalyzes phosphorylation of fructose; cytosolic enzyme
YP_002396470.1	member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers
YP_002396471.1	with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity
YP_002396472.1	with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity
YP_002396473.1	two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB
YP_002396474.1	membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB
YP_002396475.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396476.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3078876, 6998958, 3550103, 7984428; Product type t : transporter
YP_002396477.1	cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation
YP_002396478.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92184757, 1706703, 1918057; Product type e : enzyme
YP_002396479.1	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
YP_002396480.1	Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step
YP_002396481.1	Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr)
YP_002396482.1	member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex
YP_002396483.1	part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane
YP_002396484.1	forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF
YP_002396485.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396486.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91092502, 91358319, 93352541; Product type m : membrane component
YP_002396487.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002396488.1	Evidence 2b : Function of strongly homologous gene; Product type r : regulator
YP_002396489.1	riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil
YP_002396490.1	RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not
YP_002396491.1	Regulates rRNA biosynthesis by transcriptional antitermination
YP_002396492.1	catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP
YP_002396493.1	hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate
YP_002396494.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292217, 16077126; Product type e : enzyme
YP_002396495.1	catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate
YP_002396496.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89291702, 91210228; Product type e : enzyme
YP_002396497.1	catalyzes the bidirectional exonucleolytic cleavage of DNA
YP_002396498.1	Required for the synthesis of the thiazole moiety
YP_002396499.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 97039868, 99173753, 99311269
YP_002396500.1	ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis
YP_002396501.1	putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription
YP_002396502.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396503.1	converts protoheme IX and farnesyl diphosphate to heme O
YP_002396504.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330636, 90366572, 92345252, 9378722, 98021084, 11017202, 2162835; Product type c : carrier
YP_002396505.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330636, 92345252, 93349845, 9378722, 98021084, 11017202, 2162835, 2168206; Product type c : carrier
YP_002396506.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330636, 92345252, 93349845, 9378722, 98021084, 11017202, 2162835, 2168206; Product type c : carrier
YP_002396507.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92112945, 92371427, 9378722, 98021084, 11017202, 1322173, 2162835, 2162837, 2165491, 2168206, 8231804, 8618822; Product type c : carrier
YP_002396508.1	in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein
YP_002396509.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002396510.1	positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress
YP_002396511.1	Evidence 6 : Doubtful CDS
YP_002396512.1	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer
YP_002396513.1	hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates
YP_002396514.1	binds and unfolds substrates as part of the ClpXP protease
YP_002396515.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10094703, 14665623, 8939438, 91072263, 97137085, 2984174, 3042779, 3289547, 7988699, 8226758, 8294008; Product type e : enzyme
YP_002396516.1	histone-like DNA-binding protein
YP_002396517.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9670013; Product type e : enzyme
YP_002396518.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396519.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396520.1	YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His
YP_002396521.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396522.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292217; Product type e : enzyme
YP_002396523.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002396524.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 94124004, 10850996; Product type pt : putative transporter
YP_002396525.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 94124004; Product type pt : putative transporter
YP_002396526.1	indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.
YP_002396527.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22020597, 9618533, 10931328, 1645722, 7984428; Product type t : transporter
YP_002396528.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86139906, 91250410, 10876240; Product type e : enzyme
YP_002396529.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002396530.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396531.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396532.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396533.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396534.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82180540, 91310703, 9600841; Product type e : enzyme
YP_002396535.1	with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins
YP_002396536.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1956303, 7984428, 14645275
YP_002396537.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12351840, 12654283, 15111118, 15155734, 21450803, 94012493, 10920254, 7651136; Product type t : transporter
YP_002396538.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15155734, 21450803, 383699, 390095, 94012493, 10920254, 7651136; Product type t : transporter
YP_002396539.1	regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine
YP_002396540.1	small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS
YP_002396541.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396542.1	PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks
YP_002396543.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396544.1	catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis
YP_002396545.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA
YP_002396546.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15322138, 1698765, 2674903
YP_002396547.1	involved in a recombinational process of DNA repair, independent of the recBC complex
YP_002396548.1	molecular chaperone
YP_002396549.1	essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP
YP_002396550.1	protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic
YP_002396551.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9401025, 98244813, 2051480, 7721718; Product type e : enzyme
YP_002396552.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90155203, 95238302, 2051480; Product type e : enzyme
YP_002396553.1	YbaL; member of the CPA-2 family of antiporters; uncharacterized protein
YP_002396554.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803, 97074653, 8917080; Product type t : transporter
YP_002396555.1	Evidence 6 : Doubtful CDS
YP_002396556.1	catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides
YP_002396557.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396558.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396559.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002396560.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002396561.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12351646, 20105527, 11167016, 11500054, 9868784; Product type t : transporter
YP_002396562.1	catalyzes the formation of glutamate from glutamine
YP_002396563.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396564.1	activator of copper-responsive regulon genes
YP_002396565.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396566.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396567.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396568.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396569.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002396570.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002396571.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396572.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91270121, 91324311, 93163029, 93252782, 94179121, 99353977, 1864840, 8432696, 8098033; Product type e : enzyme
YP_002396573.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396574.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type t : transporter
YP_002396575.1	catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
YP_002396576.1	activator of the allDC-ylbA operon involved in allantoin utilization
YP_002396577.1	catalyzes the formation of glyoxylate from (S)-ureidoglycolate
YP_002396578.1	regulates operons involved in the utilization of allantoin
YP_002396579.1	catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate
YP_002396580.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20069628; Product type e : enzyme
YP_002396581.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1293888; Product type t : transporter
YP_002396582.1	Plays a crucial role on both purine and pyrimidine metabolism
YP_002396583.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396584.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20069628; Product type e : enzyme
YP_002396585.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396586.1	allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide
YP_002396587.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12460564, 20069628, 69151449; Product type e : enzyme
YP_002396588.1	multicopy suppressor of dominant negative ftsH mutations
YP_002396589.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396590.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396591.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2464576, 2644189, 7920643, 7940673, 7984428; Product type pe : putative enzyme
YP_002396592.1	With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway
YP_002396593.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10074353, 8117684, 89123018, 89123019, 92287929, 10574791; Product type e : enzyme
YP_002396594.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002396595.1	catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine
YP_002396596.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90272647, 91175755, 1606970, 1864365, 8601841, 9298646, 9600841; Product type e : enzyme
YP_002396597.1	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA
YP_002396598.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396599.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12837795, 1748668, 7567469; Product type pr : putative regulator
YP_002396600.1	catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate
YP_002396601.1	Evidence 6 : Doubtful CDS
YP_002396602.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002396603.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396604.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12770720, 6265806; Product type h : extrachromosomal origin
YP_002396605.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002396606.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396607.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89359086, 94042873, 94042874; Product type m : membrane component
YP_002396608.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20461235, 11283292, 11399769; Product type r : regulator
YP_002396609.1	response regulator in two-component regulatory system with CusS; regulates the copper efflux system
YP_002396610.1	with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver
YP_002396611.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 21125583, 11283292, 11399769, 12813074; Product type f : factor
YP_002396612.1	with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver
YP_002396613.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20461235, 21125583, 21178899, 21450803, 11399769, 12813074, 1711024, 7984428; Product type t : transporter
YP_002396614.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91267923, 94042931, 8626334; Product type t : transporter
YP_002396615.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396616.1	catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive
YP_002396617.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396618.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396619.1	ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity
YP_002396620.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99291074; Product type f : factor
YP_002396621.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89313305, 90132534, 91035252, 8939709, 9214294; Product type e : enzyme
YP_002396622.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92291125, 94198561, 2974033; Product type e : enzyme
YP_002396623.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396624.1	with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin
YP_002396625.1	part of the ferric enterobactin transport system; necessary for enetrobactin uptake
YP_002396626.1	with FepBDE is involved in the transport of ferric enterobactin
YP_002396627.1	with FepBCD is involved in the transport of ferric enterobactin
YP_002396628.1	with FepBCG is involved in the transport of ferric enterobactin
YP_002396629.1	protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters
YP_002396630.1	with FepCDG is involved in the transport of ferric enterobactin
YP_002396631.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89123153, 90165423, 90241936, 2110093, 2139473; Product type e : enzyme
YP_002396632.1	bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate
YP_002396633.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20183918, 90241937, 91035252, 9485415, 97361959, 2521621, 2521622; Product type e : enzyme
YP_002396634.1	catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin
YP_002396635.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2521621, 2521622, 15808744; Product type pe : putative enzyme
YP_002396636.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396637.1	member of the iron-containing alcohol dehydrogenase family; unknown function
YP_002396638.1	catalyzes the transfer of an amino moiety
YP_002396639.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12057959; Product type r : regulator
YP_002396640.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12057959; Product type r : regulator
YP_002396641.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002396642.1	Involved in disulfide bond formation
YP_002396643.1	with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate
YP_002396644.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89197774, 1592833; Product type e : enzyme
YP_002396645.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12732303, 12071968; Product type f : factor
YP_002396646.1	Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation
YP_002396647.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90151658, 90264307, 2253883, 8188249; Product type e : enzyme
YP_002396648.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9696764; Product type t : transporter
YP_002396649.1	catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA
YP_002396650.1	2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate
YP_002396651.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 84024606, 87214225; Product type e : enzyme
YP_002396652.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 84024606, 87214225; Product type e : enzyme
YP_002396653.1	acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate
YP_002396654.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 84024606, 87214225; Product type e : enzyme
YP_002396655.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11889485, 21885746, 9701802; Product type r : regulator
YP_002396656.1	regulates the expression of citAB in citrate fermentation
YP_002396657.1	responsible for the transport of C4-dicarboxylates during anaerobic growth
YP_002396658.1	catalyzes the transfer of palmitate to lipid A
YP_002396659.1	member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator
YP_002396660.1	may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling
YP_002396661.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396662.1	TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes
YP_002396663.1	catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group
YP_002396664.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396665.1	lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein
YP_002396666.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8444795
YP_002396667.1	penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors
YP_002396668.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88058785, 2644207; Product type lp : lipoprotein
YP_002396669.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89123070, 90036736, 91072213, 3316191; Product type cp : cell process
YP_002396670.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86196149, 87030266, 89174517, 2644207; Product type e : enzyme
YP_002396671.1	SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA
YP_002396672.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396673.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7929373; Product type pe : putative enzyme
YP_002396674.1	transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria
YP_002396675.1	required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA
YP_002396676.1	rare lipoprotein B; involved in the assembly of LPS in the outer membrane
YP_002396677.1	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase
YP_002396678.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11373298, 12105207, 3320963, 7567469
YP_002396679.1	Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific
YP_002396680.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11121068; Product type t : transporter
YP_002396681.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11121068; Product type t : transporter
YP_002396682.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11121068; Product type t : transporter
YP_002396683.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1091636, 1091635, 10493123, 8740179, 10972807; Product type t : transporter
YP_002396684.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396685.1	Evidence 6 : Doubtful CDS
YP_002396686.1	Transfers the fatty acyl group on membrane lipoproteins
YP_002396687.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1779764; Product type pt : putative transporter
YP_002396688.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16511207; Product type pe : putative enzyme
YP_002396689.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12762842; Product type pe : putative enzyme
YP_002396690.1	catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A)
YP_002396691.1	catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q
YP_002396692.1	functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP
YP_002396693.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16430214, 89343637; Product type e : enzyme
YP_002396694.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15066032, 90136533, 91171292, 92114782, 92356048, 2190615, 2668691, 7545108; Product type r : regulator
YP_002396695.1	catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate
YP_002396696.1	catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate
YP_002396697.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
YP_002396698.1	catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002396699.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2118530, 9636669; Product type pt : putative transporter
YP_002396700.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002396701.1	negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer
YP_002396702.1	Evidence 6 : Doubtful CDS
YP_002396703.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
YP_002396704.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20223640, 12427949; Product type cp : cell process
YP_002396705.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15808744; Product type pe : putative enzyme
YP_002396706.1	negative modulator of the initiation of chromosome replication
YP_002396707.1	catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate
YP_002396708.1	catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system
YP_002396709.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92041955; Product type e : enzyme
YP_002396710.1	response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport
YP_002396711.1	sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein
YP_002396712.1	One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex
YP_002396713.1	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
YP_002396714.1	catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
YP_002396715.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396716.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6325460, 8387990
YP_002396717.1	UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent
YP_002396718.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15175316; Product type pt : putative transporter
YP_002396719.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14519207
YP_002396720.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396721.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396722.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1729609; Product type pe : putative enzyme
YP_002396723.1	5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity
YP_002396724.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8002588; Product type ph : phenotype
YP_002396725.1	type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH
YP_002396726.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396727.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6237244, 89076355, 89123360, 9521736, 99414342, 11259408, 3309132, 6383359, 9822661; Product type m : membrane component
YP_002396728.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82124790, 89076355, 9521736, 99414342, 6383359; Product type m : membrane component
YP_002396729.1	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol
YP_002396730.1	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase
YP_002396731.1	SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide
YP_002396732.1	component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA
YP_002396733.1	catalyzes the interconversion of succinyl-CoA and succinate
YP_002396734.1	Catalyzes the only substrate-level phosphorylation in the TCA cycle
YP_002396735.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396736.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87299685, 89255232, 91035243, 1689724, 1724280, 2843510, 3138232; Product type c : carrier
YP_002396737.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87299685, 89255232, 91035243, 2843510, 3138232; Product type c : carrier
YP_002396738.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396739.1	catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components
YP_002396740.1	membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins
YP_002396741.1	membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins
YP_002396742.1	inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins
YP_002396743.1	forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA
YP_002396744.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11790745, 87133578, 92244043, 99403391, 11173492, 2687247; Product type lp : lipoprotein
YP_002396745.1	periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity
YP_002396746.1	3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate
YP_002396747.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 219824, 90330519; Product type t : transporter
YP_002396748.1	involved in zinc efflux across the cytoplasmic membrane
YP_002396749.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396750.1	catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive
YP_002396751.1	2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate
YP_002396752.1	catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose
YP_002396753.1	catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism
YP_002396754.1	catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P
YP_002396755.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89274199, 92253563, 92338916, 3022232, 6301942, 8564363, 8611559, 8931134, 9174344, 9271499, 9708982; Product type e : enzyme
YP_002396756.1	contains 2 ATP-binding cassettes; involved in the transport of molybdenum
YP_002396757.1	Evidence 6 : Doubtful CDS
YP_002396758.1	represses the modABCD operon and activates the moaABCD and napFDAGHBC operons
YP_002396759.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396760.1	with ModCB is involved in the high-affinity transport of molybdate
YP_002396761.1	part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE
YP_002396762.1	Part of the ABC transporter complex modABC involved in molybdenum import
YP_002396763.1	YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily
YP_002396764.1	catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate
YP_002396765.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396766.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396767.1	Evidence 6 : Doubtful CDS
YP_002396768.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11782506; Product type pe : putative enzyme
YP_002396769.1	outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family
YP_002396770.1	YbhB; similar to rat and human kinase inhibitory proteins
YP_002396771.1	catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate
YP_002396772.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11834738, 12475249, 14704425, 14967041, 20250955, 89066784, 94170810, 94190882, 97382445, 11686925; Product type e : enzyme
YP_002396773.1	catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine
YP_002396774.1	putative methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth
YP_002396775.1	DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium
YP_002396776.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion
YP_002396777.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16272399; Product type pe : putative enzyme
YP_002396778.1	Evidence 6 : Doubtful CDS
YP_002396779.1	together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z
YP_002396780.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93368423; Product type pf : putative factor
YP_002396781.1	MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis
YP_002396782.1	catalyzes the conversion of molybdopterin precursor Z into molybdopterin
YP_002396783.1	catalyzes the conversion of molybdopterin precursor Z into molybdopterin
YP_002396784.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396785.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396786.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396787.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20102623, 10634942; Product type e : enzyme
YP_002396788.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396789.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396790.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396791.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396792.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396793.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16092522; Product type pt : putative transporter
YP_002396794.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002396795.1	this helicase is not essential cell growth
YP_002396796.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396797.1	helicase involved in DNA repair and perhaps also replication
YP_002396798.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396799.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8405966; Product type pe : putative enzyme
YP_002396800.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396801.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396802.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396803.1	Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein
YP_002396804.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396805.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396806.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002396807.1	similar to ATP-binding component of ABC transporters
YP_002396808.1	similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine
YP_002396809.1	similar to periplasmic-binding component of ABC transporters
YP_002396810.1	binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage
YP_002396811.1	OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains
YP_002396812.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16514146; Product type pe : putative enzyme
YP_002396813.1	Transcriptional regulator that represses the manganese transporter MntH when manganese is present
YP_002396814.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396815.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10493123, 9298646
YP_002396816.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11916677; Product type pt : putative transporter
YP_002396817.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15657928; Product type e : enzyme
YP_002396818.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16218870; Product type pe : putative enzyme
YP_002396819.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15581584; Product type pe : putative enzyme
YP_002396820.1	similar to transaldolase from Escherichia coli; many organisms have multiple copies
YP_002396821.1	ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase
YP_002396822.1	is involved in the formation of active molybdenum cofactor and the chelation of molybdenum
YP_002396823.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15159592, 20508248, 3045084, 7984428; Product type e : enzyme
YP_002396824.1	with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains
YP_002396825.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17366475; Product type pt : putative transporter
YP_002396826.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396827.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396828.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396829.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15380559; Product type pe : putative enzyme
YP_002396830.1	catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit
YP_002396831.1	BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing
YP_002396832.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16522795, 16864586; Product type e : enzyme
YP_002396833.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396834.1	penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains
YP_002396835.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89231635, 89336786, 92231401, 2994018; Product type r : regulator
YP_002396836.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15778224; Product type e : enzyme
YP_002396837.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10022825, 12578981, 14688269, 21217867, 21450803, 9079913, 9644262, 99030337, 8655497; Product type t : transporter
YP_002396838.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396839.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15808744; Product type pe : putative enzyme
YP_002396840.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396841.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002396842.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396843.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396844.1	functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase
YP_002396845.1	YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function
YP_002396846.1	NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds
YP_002396847.1	responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6
YP_002396848.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396849.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106992, 9651355, 9298646, 8416922; Product type t : transporter
YP_002396850.1	part of the PotFGHI ATP-dependent putrescine transporter
YP_002396851.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106992; Product type t : transporter
YP_002396852.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396853.1	RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA
YP_002396854.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93273744, 9298646, 9600841, 8801422; Product type t : transporter
YP_002396855.1	with ArtPQJI acts to transport arginine across the inner membrane
YP_002396856.1	with ArtPMJI transports arginine across the inner membrane
YP_002396857.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93273744, 9298646, 9600841, 8801422, 9740056; Product type t : transporter
YP_002396858.1	With ArtMQJI transports arginine across the inner membrane
YP_002396859.1	induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS
YP_002396860.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396861.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396862.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396863.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396864.1	low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine
YP_002396865.1	catalyzes the formation of acetate from pyruvate
YP_002396866.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20117674; Product type e : enzyme
YP_002396867.1	catalyzes the reduction of hydroxylamine to ammonia and water
YP_002396868.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396869.1	porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure
YP_002396870.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396871.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396872.1	confers macrolide resistance via active drug efflux
YP_002396873.1	with MacA is involved in the export of macrolide
YP_002396874.1	inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible
YP_002396875.1	involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA
YP_002396876.1	ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates
YP_002396877.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396878.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396879.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396880.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396881.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396882.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396883.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396884.1	stimulates the activities of the other two initiation factors, IF-2 and IF-3
YP_002396885.1	leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys
YP_002396886.1	in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c
YP_002396887.1	in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c
YP_002396888.1	catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding
YP_002396889.1	mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system
YP_002396890.1	DNA-binding membrane protein required for chromosome resolution and partitioning
YP_002396891.1	participates with LolB in the incorporation of lipoprotein into the outer membrane
YP_002396892.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7567469, 7628437, 11459952, 11029431; Product type cp : cell process
YP_002396893.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002396894.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002396895.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002396896.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 1825255; Product type h : extrachromosomal origin
YP_002396897.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002396898.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002396899.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002396900.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002396901.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002396902.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002396903.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002396904.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002396905.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002396906.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002396907.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002396908.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002396909.1	Evidence 6 : Doubtful CDS
YP_002396910.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002396911.1	Evidence 5 : No homology to any previously reported sequences
YP_002396912.1	Evidence 5 : No homology to any previously reported sequences
YP_002396913.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002396914.1	Evidence 5 : No homology to any previously reported sequences
YP_002396915.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002396916.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002396917.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002396918.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002396919.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002396920.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002396921.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002396922.1	Evidence 5 : No homology to any previously reported sequences
YP_002396923.1	Evidence 5 : No homology to any previously reported sequences
YP_002396924.1	Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
YP_002396925.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002396926.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002396927.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002396928.1	Evidence 5 : No homology to any previously reported sequences
YP_002396929.1	Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin
YP_002396930.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002396931.1	Evidence 5 : No homology to any previously reported sequences
YP_002396932.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002396933.1	Evidence 5 : No homology to any previously reported sequences
YP_002396934.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002396935.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396936.1	Evidence 5 : No homology to any previously reported sequences
YP_002396937.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002396938.1	Evidence 5 : No homology to any previously reported sequences
YP_002396939.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002396940.1	Evidence 5 : No homology to any previously reported sequences
YP_002396941.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396942.1	Evidence 5 : No homology to any previously reported sequences
YP_002396943.1	Evidence 5 : No homology to any previously reported sequences
YP_002396944.1	Evidence 5 : No homology to any previously reported sequences
YP_002396945.1	Evidence 5 : No homology to any previously reported sequences
YP_002396946.1	Evidence 5 : No homology to any previously reported sequences
YP_002396947.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002396948.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002396949.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91008971, 92011349, 94171715, 10801884, 3062312; Product type e : enzyme
YP_002396950.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91070067, 91355180, 92011349, 3062312; Product type e : enzyme
YP_002396951.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91008971, 92011349, 3062312, 8429002; Product type e : enzyme
YP_002396952.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9782055, 3062312, 11714269; Product type pe : putative enzyme
YP_002396953.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002396954.1	activates pyruvate formate-lyase 1 under anaerobic conditions
YP_002396955.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91064082, 92276323, 10504733, 1310545, 2651404, 3053170, 9629924; Product type e : enzyme
YP_002396956.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293770, 2651404; Product type t : transporter
YP_002396957.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396958.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396959.1	catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine
YP_002396960.1	catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
YP_002396961.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002396962.1	Catalyzes the formation of (d)CDP from ATP and (d)CMP
YP_002396963.1	in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins
YP_002396964.1	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
YP_002396965.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396966.1	involved in the transport of lipid A across the inner membrane
YP_002396967.1	transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate
YP_002396968.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396969.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002396970.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002396971.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396972.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396973.1	CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS
YP_002396974.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396975.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002396976.1	involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA
YP_002396977.1	acts with MukB and MukE to condense the chromosome and allow for segregation during cell division
YP_002396978.1	acts with MukB and MukF to condense the chromosome and allow for segregation during cell division
YP_002396979.1	SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects
YP_002396980.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002396981.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396982.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14529289; Product type pe : putative enzyme
YP_002396983.1	catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate
YP_002396984.1	outer membrane porin F; 1a; Ia; b
YP_002396985.1	catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002396986.1	catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate
YP_002396987.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21101837, 86164315, 87163509, 2436977, 3018440; Product type e : enzyme
YP_002396988.1	part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease
YP_002396989.1	part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease
YP_002396990.1	catalyzes the release of sulfite from alkanesulfonates
YP_002396991.1	part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease
YP_002396992.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20245523, 99410391, 99436146, 8774726; Product type e : enzyme
YP_002396993.1	catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors
YP_002396994.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002396995.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1327782; Product type pe : putative enzyme
YP_002396996.1	catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA
YP_002396997.1	Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth
YP_002396998.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95270582; Product type cp : cell process
YP_002396999.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95270582; Product type cp : cell process
YP_002397000.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397001.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1101029, 90207255, 2832401, 8440252; Product type f : factor
YP_002397002.1	catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP
YP_002397003.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397004.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397005.1	OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d
YP_002397006.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10368140, 91072263, 93163041, 98348458, 3297925, 6253901, 6306396; Product type cp : cell process
YP_002397007.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397008.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397009.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397010.1	catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand
YP_002397011.1	catalyzes the formation of methylglyoxal from glycerone phosphate
YP_002397012.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397013.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397014.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12700277, 15569148; Product type f : factor
YP_002397015.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397016.1	catalyzes the hydrolysis of acylphosphate
YP_002397017.1	transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs
YP_002397018.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6376117; Product type m : membrane component
YP_002397019.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397020.1	Evidence 5 : No homology to any previously reported sequences
YP_002397021.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397022.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397023.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3041373; Product type h : extrachromosomal origin
YP_002397024.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397025.1	Evidence 5 : No homology to any previously reported sequences
YP_002397026.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397027.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397028.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397029.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397030.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397031.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397032.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397033.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397034.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397035.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397036.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397037.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397038.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397039.1	Evidence 6 : Doubtful CDS
YP_002397040.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397041.1	Evidence 6 : Doubtful CDS
YP_002397042.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397043.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397044.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397045.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397046.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397047.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397048.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397049.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397050.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397051.1	Evidence 6 : Doubtful CDS
YP_002397052.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397053.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397054.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397055.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin
YP_002397056.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397057.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397058.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397059.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397060.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397061.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397062.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397063.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397064.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397065.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397066.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397067.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397068.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397069.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397070.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397071.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397072.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397073.1	Evidence 6 : Doubtful CDS
YP_002397074.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397075.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397076.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397077.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397078.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397079.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397080.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86192450, 90202716, 92215587; Product type e : enzyme
YP_002397081.1	involved in hydrogen cycling during fermentative growth
YP_002397082.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202716, 91310595, 92215587; Product type c : carrier
YP_002397083.1	HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1)
YP_002397084.1	involved in processing hydrogenase proteins HyaA and HyaB
YP_002397085.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202716, 91310595, 92215587; Product type f : factor
YP_002397086.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92049231, 96198179; Product type c : carrier
YP_002397087.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92049231, 96198179; Product type c : carrier
YP_002397088.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20122624, 92049231, 93054596, 10696472, 2168385, 3038201, 8387749; Product type e : enzyme
YP_002397089.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 9484881, 9439003; Product type f : factor
YP_002397090.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9484881, 15466053, 8631696, 9439003; Product type r : regulator
YP_002397091.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15317805, 11544213; Product type pr : putative regulator
YP_002397092.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002397093.1	Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide
YP_002397094.1	periplasmic sensory protein associated with the TorRS two-component regulatory system
YP_002397095.1	response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes
YP_002397096.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293785, 94314186, 99340208, 11056172, 11562502; Product type c : carrier
YP_002397097.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88193091, 90089471, 94293785, 8302830, 8022286; Product type e : enzyme
YP_002397098.1	TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor
YP_002397099.1	with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA
YP_002397100.1	functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock
YP_002397101.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002397102.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002397103.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397104.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16322580, 93296226, 9694845; Product type pr : putative regulator
YP_002397105.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397106.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397107.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397108.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397109.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 6458018, 6221115; Product type h : extrachromosomal origin
YP_002397110.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397111.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2199308; Product type h : extrachromosomal origin
YP_002397112.1	Evidence 5 : No homology to any previously reported sequences
YP_002397113.1	Rac prophage Kil protein; Kil overexpression leads to morphological defects and inhibits cell division
YP_002397114.1	Evidence 5 : No homology to any previously reported sequences
YP_002397115.1	Evidence 5 : No homology to any previously reported sequences
YP_002397116.1	Evidence 5 : No homology to any previously reported sequences
YP_002397117.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397118.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397119.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397120.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397121.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397122.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397123.1	Evidence 5 : No homology to any previously reported sequences
YP_002397124.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397125.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397126.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397127.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397128.1	Evidence 5 : No homology to any previously reported sequences
YP_002397129.1	Evidence 5 : No homology to any previously reported sequences
YP_002397130.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397131.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397132.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397133.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397134.1	Evidence 6 : Doubtful CDS
YP_002397135.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002397136.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397137.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397138.1	Evidence 5 : No homology to any previously reported sequences
YP_002397139.1	Evidence 6 : Doubtful CDS
YP_002397140.1	Evidence 6 : Doubtful CDS
YP_002397141.1	Evidence 6 : Doubtful CDS
YP_002397142.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397143.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397144.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2019562; Product type h : extrachromosomal origin
YP_002397145.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397146.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397147.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397148.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin
YP_002397149.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397150.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397151.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397152.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397153.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397154.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397155.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397156.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397157.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397158.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397159.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397160.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397161.1	Evidence 6 : Doubtful CDS
YP_002397162.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397163.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397164.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397165.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397166.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397167.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397168.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397169.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397170.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397171.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397172.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397173.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397174.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397175.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397176.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397177.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397178.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12057959; Product type r : regulator
YP_002397179.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397180.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397181.1	Evidence 6 : Doubtful CDS
YP_002397182.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397183.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type t : transporter
YP_002397184.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542, 10633095; Product type e : enzyme
YP_002397185.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type e : enzyme
YP_002397186.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type e : enzyme
YP_002397187.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type e : enzyme
YP_002397188.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type e : enzyme
YP_002397189.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type e : enzyme
YP_002397190.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type r : regulator
YP_002397191.1	proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein
YP_002397192.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12923181, 88213396, 91227628, 93132799, 98359785, 1400239, 1567896, 3053649, 3053687, 3302614, 3325781, 8119910; Product type t : transporter
YP_002397193.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter
YP_002397194.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 17627767, 10493123; Product type t : transporter
YP_002397195.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 17627767, 16551627, 15375152; Product type t : transporter
YP_002397196.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8444794, 2160940; Product type pe : putative enzyme
YP_002397197.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397198.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11237876, 10493123; Product type e : enzyme
YP_002397199.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12661000; Product type pe : putative enzyme
YP_002397200.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397201.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397202.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8817489; Product type lp : lipoprotein
YP_002397203.1	nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex
YP_002397204.1	chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex
YP_002397205.1	activates the csgBA and csgDEFG operons involved in biofilm formation
YP_002397206.1	CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface
YP_002397207.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89201357, 93023873, 1677357, 8459772, 8817489, 1357528; Product type s : structure
YP_002397208.1	involved in autoagglutination of curliated cells; not involved in production of curli fibers
YP_002397209.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397210.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397211.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397212.1	required for the transfer of succinyl residues to the glucan backbone
YP_002397213.1	Evidence 6 : Doubtful CDS
YP_002397214.1	Evidence 6 : Doubtful CDS
YP_002397215.1	involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan
YP_002397216.1	necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space
YP_002397217.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002397218.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 92165719
YP_002397219.1	Confers resistance to fosfomycin and deoxycholate
YP_002397220.1	Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA
YP_002397221.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1840644
YP_002397222.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15741337, 11298273, 1840644, 9298646; Product type c : carrier
YP_002397223.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002397224.1	catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids
YP_002397225.1	BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing
YP_002397226.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9606202, 11152126, 11230150, 8682790; Product type f : factor
YP_002397227.1	catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis
YP_002397228.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002397229.1	cofactor involved in the reduction of disulfides
YP_002397230.1	Confers resistance to norfloxacin and enoxacin
YP_002397231.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88121676, 90136529, 1356970; Product type e : enzyme
YP_002397232.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1356970, 2828880
YP_002397233.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397234.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397235.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10320579; Product type f : factor
YP_002397236.1	regulates the flagellar specific sigma28 transcription factor
YP_002397237.1	required for the assembly of the flagellar basal body P-ring
YP_002397238.1	with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella
YP_002397239.1	with FlgF and B makes up the proximal portion of the flagellar basal body rod
YP_002397240.1	acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production
YP_002397241.1	the hook connects flagellar basal body to the flagellar filament
YP_002397242.1	FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod
YP_002397243.1	makes up the distal portion of the flagellar basal body rod
YP_002397244.1	part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod
YP_002397245.1	part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum
YP_002397246.1	Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space
YP_002397247.1	with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook
YP_002397248.1	with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes
YP_002397249.1	bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase
YP_002397250.1	catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA
YP_002397251.1	Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell
YP_002397252.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 90008815, 1447160
YP_002397253.1	some L32 proteins have zinc finger motifs consisting of CXXC while others do not
YP_002397254.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY
YP_002397255.1	FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs
YP_002397256.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92052166, 92183950, 92210530, 92234941, 7700236, 7768883, 9298646; Product type e : enzyme
YP_002397257.1	catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_002397258.1	carries the fatty acid chain in fatty acid biosynthesis
YP_002397259.1	FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP
YP_002397260.1	catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate
YP_002397261.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002397262.1	catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP)
YP_002397263.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA
YP_002397264.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8505303, 8509334, 10747959; Product type pe : putative enzyme
YP_002397265.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
YP_002397266.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90286919, 3032906, 10529396; Product type t : transporter
YP_002397267.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15703176, 10493123, 2162465; Product type e : enzyme
YP_002397268.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397269.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002397270.1	catalyzes the phosphorylation of thiamine to thiamine phosphate
YP_002397271.1	hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides
YP_002397272.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397273.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14766919, 20130027, 81256452, 92296775, 94042945, 99441207, 6265208; Product type e : enzyme
YP_002397274.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6265208, 7984428
YP_002397275.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002397276.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14727089
YP_002397277.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397278.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14602898, 90158497, 92107993, 8465200; Product type f : factor
YP_002397279.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397280.1	part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane
YP_002397281.1	outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone
YP_002397282.1	part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane
YP_002397283.1	catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine
YP_002397284.1	Modulates the activities of several enzymes which are inactive in their acetylated form
YP_002397285.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397286.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397287.1	can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate
YP_002397288.1	can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component
YP_002397289.1	can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component
YP_002397290.1	functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase
YP_002397291.1	Evidence 6 : Doubtful CDS
YP_002397292.1	catalyzes the release of the N-terminal amino acid from a tripeptide
YP_002397293.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397294.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92105017; Product type r : regulator
YP_002397295.1	response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress
YP_002397296.1	Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide
YP_002397297.1	HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis
YP_002397298.1	catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs
YP_002397299.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292217; Product type e : enzyme
YP_002397300.1	catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA
YP_002397301.1	Converts isocitrate to alpha ketoglutarate
YP_002397302.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002397303.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002397304.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397305.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002397306.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002397307.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002397308.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002397309.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397310.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397311.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12654809, 10085045; Product type m : membrane component
YP_002397312.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12654809, 10085045; Product type m : membrane component
YP_002397313.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12654809, 10085045; Product type m : membrane component
YP_002397314.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12654809, 10085045; Product type t : transporter
YP_002397315.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397316.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397317.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397318.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002397319.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16533062, 15453820; Product type pe : putative enzyme
YP_002397320.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397321.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397322.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397323.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397324.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397325.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397326.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397327.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397328.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397329.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397330.1	works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell
YP_002397331.1	ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums
YP_002397332.1	blocks the formation of polar Z-ring septums
YP_002397333.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397334.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397335.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397336.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15551868; Product type pe : putative enzyme
YP_002397337.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397338.1	binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization
YP_002397339.1	binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization
YP_002397340.1	disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein
YP_002397341.1	involved in regulation of intracellular pH under alkaline conditions
YP_002397342.1	Multifunctional regulator of fatty acid metabolism
YP_002397343.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397344.1	catalyzes the oxidative deamination of D-amino acids
YP_002397345.1	catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA
YP_002397346.1	the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli
YP_002397347.1	catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine
YP_002397348.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98317285; Product type e : enzyme
YP_002397349.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 11031114; Product type cp : cell process
YP_002397350.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002397351.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor
YP_002397352.1	involved in molybdenum transport
YP_002397353.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397354.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397355.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002397356.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397357.1	phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL
YP_002397358.1	with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone
YP_002397359.1	with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase
YP_002397360.1	Positively regulates the dhaKLM operon from a sigma-70 promoter
YP_002397361.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397362.1	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1
YP_002397363.1	Enables the recycling of peptidyl-tRNAs produced at termination of translation
YP_002397364.1	YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function
YP_002397365.1	putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport
YP_002397366.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP
YP_002397367.1	An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis
YP_002397368.1	Incorporates lipoproteins in the outer membrane after they are released by the LolA protein
YP_002397369.1	catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins
YP_002397370.1	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2
YP_002397371.1	HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB
YP_002397372.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10322010; Product type pr : putative regulator
YP_002397373.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10322010; Product type pr : putative regulator
YP_002397374.1	catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis
YP_002397375.1	Evidence 1b : Function experimentally demonstrated in the studied species; Product type f : factor
YP_002397376.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93266586, 94193576, 94292460; Product type t : transporter
YP_002397377.1	in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions
YP_002397378.1	Evidence 1b : Function experimentally demonstrated in the studied species; Product type r : regulator
YP_002397379.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397380.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7567469; Product type pf : putative factor
YP_002397381.1	two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase
YP_002397382.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92276349, 92374842, 94083940, 2649492, 2657652, 2668029; Product type r : regulator
YP_002397383.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397384.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91258310, 2657652, 2668029; Product type t : transporter
YP_002397385.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 74167294, 89384449, 92121125, 2233673, 2668029, 2995309, 3053688, 3308846, 6094247; Product type e : enzyme
YP_002397386.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 74167294, 89384449, 92121125, 1321049, 2832376, 3053688, 8383531, 8388253, 8664273, 9516445; Product type c : carrier
YP_002397387.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89384449, 92121125, 9632249, 2832376; Product type f : factor
YP_002397388.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 75114694, 89384449, 92121125, 2832376, 3053688; Product type c : carrier
YP_002397389.1	Evidence 6 : Doubtful CDS
YP_002397390.1	produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine
YP_002397391.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397392.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397393.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339606, 12912910, 9495753; Product type r : regulator
YP_002397394.1	together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose
YP_002397395.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89056689, 94335643, 95267838, 95286558, 99355427, 2404280, 11298273; Product type r : regulator
YP_002397396.1	catalyzes the formation of thymidine 5'-phosphate from thymidine
YP_002397397.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12783863, 4301680, 89291706, 91200315; Product type e : enzyme
YP_002397398.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397399.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397400.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20256410, 86111605, 90256748, 92325017, 2015910, 9298646, 9600841, 2187863, 8740179, 9740056, 10972807; Product type t : transporter
YP_002397401.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606, 93106975, 2187863; Product type t : transporter
YP_002397402.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606; Product type t : transporter
YP_002397403.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606; Product type t : transporter
YP_002397404.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606; Product type t : transporter
YP_002397405.1	highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein
YP_002397406.1	catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol)
YP_002397407.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397408.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12220501, 12912904, 94224769, 98319474; Product type t : transporter
YP_002397409.1	unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity
YP_002397410.1	membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins
YP_002397411.1	YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins
YP_002397412.1	Involved in cell division; probably involved in intracellular septation
YP_002397413.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397414.1	receptor for colicin S4
YP_002397415.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397416.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397417.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1849492, 12770720; Product type h : extrachromosomal origin
YP_002397418.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002397419.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397420.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397421.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2990907; Product type h : extrachromosomal origin
YP_002397422.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397423.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397424.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397425.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397426.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397427.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397428.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397429.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397430.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397431.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397432.1	Evidence 6 : Doubtful CDS
YP_002397433.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin
YP_002397434.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397435.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397436.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397437.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397438.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397439.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397440.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397441.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397442.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397443.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397444.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397445.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397446.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397447.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002397448.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002397449.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002397450.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397451.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397452.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 11686382, 11282477, 9562894, 8878031; Product type f : factor
YP_002397453.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 11686382, 11282477, 9562894, 8878031; Product type f : factor
YP_002397454.1	Evidence 2b : Function of strongly homologous gene; Product type t : transporter
YP_002397455.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397456.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397457.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397458.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397459.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397460.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397461.1	Evidence 5 : No homology to any previously reported sequences
YP_002397462.1	catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis
YP_002397463.1	catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate
YP_002397464.1	monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate
YP_002397465.1	bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis
YP_002397466.1	with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine
YP_002397468.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397469.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397470.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397471.1	catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA
YP_002397472.1	catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide
YP_002397473.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397474.1	SohB; periplasmic protein; member of the peptidase S49 family
YP_002397475.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3029379, 7567469, 9868784
YP_002397476.1	Evidence 6 : Doubtful CDS
YP_002397477.1	catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity
YP_002397478.1	LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation
YP_002397479.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397480.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397481.1	catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate
YP_002397482.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89033893, 92104964; Product type e : enzyme
YP_002397483.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397484.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397485.1	type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase
YP_002397486.1	involved in start site selection during the initiation of translation
YP_002397487.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92078100, 2644204; Product type lp : lipoprotein
YP_002397488.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16451192; Product type r : regulator
YP_002397489.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397490.1	c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP
YP_002397491.1	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
YP_002397492.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397493.1	Catalyzes a key regulatory step in fatty acid biosynthesis
YP_002397494.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002397495.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397496.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397497.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397498.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397499.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 10720487, 9634580; Product type t : transporter
YP_002397500.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 10720487, 9634580, 1987159; Product type t : transporter
YP_002397501.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 9634580; Product type t : transporter
YP_002397502.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 9634580; Product type t : transporter
YP_002397503.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 9634580; Product type t : transporter
YP_002397504.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397505.1	transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor
YP_002397506.1	involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF
YP_002397507.1	acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding
YP_002397508.1	with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock
YP_002397509.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91295203, 97303082; Product type ph : phenotype
YP_002397510.1	rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide
YP_002397511.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397512.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397513.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397514.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397515.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397516.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397517.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397518.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397519.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11972617; Product type pe : putative enzyme
YP_002397520.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397521.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20464934, 89327119, 9721282; Product type t : transporter
YP_002397522.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002397523.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397524.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397525.1	regulates genes involved in the biosynthesis and transport of aromatic amino acids
YP_002397526.1	antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein
YP_002397527.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11747447, 11747448, 7499381; Product type e : enzyme
YP_002397528.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12511517; Product type e : enzyme
YP_002397529.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397530.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17366475; Product type pr : putative regulator
YP_002397531.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10438753, 9495761; Product type t : transporter
YP_002397532.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397533.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397534.1	with UspC and UspD is involved in resistance to UV irradiation
YP_002397535.1	Global transcription factor that controls the expression of over 100 target genes in response to anoxia
YP_002397536.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88067749, 91161525, 94252990, 98125595, 1520330; Product type e : enzyme
YP_002397537.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397538.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002397539.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397540.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397541.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397542.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16045609; Product type pe : putative enzyme
YP_002397543.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397544.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397545.1	exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA
YP_002397546.1	TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs
YP_002397547.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397548.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12732303, 12381839, 11849540, 9298646; Product type f : factor
YP_002397549.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9025293; Product type pe : putative enzyme
YP_002397550.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397551.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12892888, 8349564, 9025293; Product type f : factor
YP_002397552.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4297266, 89123040, 90198524, 8349564, 9025293; Product type e : enzyme
YP_002397553.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397554.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002397555.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397556.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor
YP_002397557.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397558.1	FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds
YP_002397559.1	involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain
YP_002397560.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397561.1	NAD-linked
YP_002397562.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9622357, 9019141, 1917845, 3780374; Product type e : enzyme
YP_002397563.1	B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm
YP_002397564.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397565.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002397566.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397567.1	involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans
YP_002397568.1	Evidence 6 : Doubtful CDS
YP_002397569.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397570.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89364711; Product type e : enzyme
YP_002397571.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397572.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94222856, 2060788; Product type t : transporter
YP_002397573.1	with TehA confers resistance to tellurite
YP_002397574.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002397575.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1885518; Product type pt : putative transporter
YP_002397576.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002397577.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397578.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397579.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15223311; Product type pr : putative regulator
YP_002397580.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11683869; Product type pt : putative transporter
YP_002397581.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397582.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397583.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397584.1	catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation
YP_002397585.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397586.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397587.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397588.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397589.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397590.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor
YP_002397591.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397592.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 76005443; Product type t : transporter
YP_002397593.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397594.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397595.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397596.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397597.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397598.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20267568; Product type e : enzyme
YP_002397599.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14611652, 15103639, 2233673
YP_002397600.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91042410; Product type e : enzyme
YP_002397601.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91042410, 92186712; Product type f : factor
YP_002397602.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91042410; Product type c : carrier
YP_002397603.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91042410; Product type e : enzyme
YP_002397604.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95266795, 2233673; Product type t : transporter
YP_002397605.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12410826; Product type t : transporter
YP_002397606.1	Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme
YP_002397607.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 76005553, 90375017, 92332427, 11884747, 1834669; Product type c : carrier
YP_002397608.1	nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase
YP_002397609.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397610.1	similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs
YP_002397611.1	malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate
YP_002397612.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10498711, 13129944; Product type f : factor
YP_002397613.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14512736, 91350191, 9298646; Product type m : membrane component
YP_002397614.1	heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate
YP_002397615.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10960106; Product type lp : lipoprotein
YP_002397616.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15795232, 15489450; Product type t : transporter
YP_002397617.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12912902, 92155241, 92394884, 99406302, 8455549; Product type e : enzyme
YP_002397618.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pr : putative regulator
YP_002397619.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397620.1	regulates the cellular response to acid resistance
YP_002397621.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397622.1	in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family
YP_002397623.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397624.1	Evidence 5 : No homology to any previously reported sequences
YP_002397625.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91358364, 94292428, 15576765; Product type r : regulator
YP_002397626.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91358364, 94292428, 15576765, 8021189; Product type r : regulator
YP_002397627.1	catalyzes the formation of D-tagaturonate from D-altronate
YP_002397628.1	in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase
YP_002397629.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002397630.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10094697, 99369894, 8383113, 10438792; Product type t : transporter
YP_002397631.1	protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function
YP_002397632.1	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
YP_002397633.1	transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF
YP_002397634.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8383113
YP_002397635.1	converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism
YP_002397636.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20305052; Product type t : transporter
YP_002397637.1	YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters
YP_002397638.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397639.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 216006, 8226676; Product type e : enzyme
YP_002397640.1	NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine
YP_002397641.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002397642.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12084818; Product type pc : putative carrier
YP_002397643.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397644.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002397645.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002397646.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002397647.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 10722621, 17220264, 9194704, 9743528; Product type e : enzyme
YP_002397648.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10722621
YP_002397649.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 16988252, 10722621; Product type f : factor
YP_002397650.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397651.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397652.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397653.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397654.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397655.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type f : factor
YP_002397656.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7999761, 10426954; Product type pr : putative regulator
YP_002397657.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397658.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397659.1	Evidence 2b : Function of strongly homologous gene; Product type t : transporter
YP_002397660.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 11686382, 11282477, 9562894, 8878031; Product type f : factor
YP_002397661.1	Evidence 2b : Function of strongly homologous gene; Product type f : factor
YP_002397662.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397663.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397664.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002397665.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002397666.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397667.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002397668.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002397669.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397670.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397671.1	Evidence 2b : Function of strongly homologous gene; Product type s : structure
YP_002397672.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397673.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397674.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397675.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397676.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397677.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397678.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397679.1	Evidence 6 : Doubtful CDS; Product type h : extrachromosomal origin
YP_002397680.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397681.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397682.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397683.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397684.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin
YP_002397685.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397686.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002397687.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397688.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397689.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397690.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397691.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397692.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397693.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397694.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397695.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 3624233; Product type r : regulator
YP_002397696.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397697.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397698.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397699.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397700.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397701.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397702.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397703.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397704.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397705.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397706.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397707.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397708.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3041373; Product type h : extrachromosomal origin
YP_002397709.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2199308; Product type h : extrachromosomal origin
YP_002397710.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397711.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397712.1	Evidence 6 : Doubtful CDS
YP_002397713.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7545940; Product type pe : putative enzyme
YP_002397714.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 93341455, 94310441; Product type pe : putative enzyme
YP_002397715.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397716.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397717.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94357898; Product type e : enzyme
YP_002397718.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397719.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9868784
YP_002397720.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14522592; Product type e : enzyme
YP_002397721.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14522592; Product type c : carrier
YP_002397722.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14522592; Product type m : membrane component
YP_002397723.1	binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane
YP_002397724.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12384697; Product type pt : putative transporter
YP_002397725.1	DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium
YP_002397726.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10318813, 20490366, 6989798, 99340206, 99395104, 99398866, 7766024; Product type r : regulator
YP_002397727.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002397728.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397729.1	required for growth and survival under moderately acid conditions
YP_002397730.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397731.1	with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS
YP_002397732.1	with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS
YP_002397733.1	Evidence 6 : Doubtful CDS
YP_002397734.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397735.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397736.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397737.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397738.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397739.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397740.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397741.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397742.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397743.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8885267; Product type h : extrachromosomal origin
YP_002397744.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397745.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397746.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397747.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397748.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397749.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397750.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397751.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397752.1	Evidence 5 : No homology to any previously reported sequences
YP_002397753.1	Evidence 5 : No homology to any previously reported sequences
YP_002397754.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002397755.1	Evidence 5 : No homology to any previously reported sequences
YP_002397756.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002397757.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002397758.1	Evidence 6 : Doubtful CDS
YP_002397759.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14727089; Product type pm : putative membrane component
YP_002397760.1	catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme
YP_002397761.1	forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm
YP_002397762.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397763.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1311296; Product type pt : putative transporter
YP_002397764.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14617668; Product type e : enzyme
YP_002397765.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397766.1	response regulator in two-component regulatory system with RstB
YP_002397767.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93086426, 1495392, 1925016, 2646639; Product type r : regulator
YP_002397768.1	binds to DNA replication terminator sequences to prevent passage of replication forks
YP_002397769.1	class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle
YP_002397770.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88193096, 88268900, 92011457, 3005475, 6328431, 9298646; Product type e : enzyme
YP_002397771.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82100097, 6397402; Product type e : enzyme
YP_002397772.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397773.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15774881; Product type t : transporter
YP_002397774.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3534890; Product type t : transporter
YP_002397775.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87041472, 88038341, 2103475, 8125312; Product type e : enzyme
YP_002397776.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88038341, 2823062, 3934044, 11115104; Product type r : regulator
YP_002397777.1	Acts on the hydroxyl group at position 7 of the steroid frame
YP_002397778.1	regulates malXY which are involved in maltose-glucose transport
YP_002397779.1	phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site
YP_002397780.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20164451, 7665481, 91310596; Product type e : enzyme
YP_002397781.1	catalyzes the formation of inosine from adenosine
YP_002397782.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397783.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20392465, 10931331; Product type m : membrane component
YP_002397784.1	YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes
YP_002397785.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397786.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10411911, 10637328, 12773378; Product type pm : putative membrane component
YP_002397787.1	part of membrane-bound complex thought to be involved in electron transport to nitrogen
YP_002397788.1	part of membrane-bound complex thought to be involved in electron transport to nitrogen
YP_002397789.1	RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents
YP_002397790.1	part of membrane-bound complex hought to be involved in electron transport to nitrogen
YP_002397791.1	in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase
YP_002397792.1	DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines
YP_002397793.1	mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation
YP_002397794.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95096109, 2185038, 9680481; Product type e : enzyme
YP_002397795.1	catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal
YP_002397796.1	catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr)
YP_002397797.1	catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate
YP_002397798.1	MliC; membrane-bound lysozyme inhibitor of c-type lysozyme
YP_002397799.1	catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling
YP_002397800.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8544813; Product type lp : lipoprotein
YP_002397801.1	Transcription regulator that can both activate or repress expression
YP_002397802.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397803.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12900028; Product type e : enzyme
YP_002397804.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397805.1	SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water
YP_002397806.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397807.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002397808.1	FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide
YP_002397809.1	Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione
YP_002397810.1	Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A)
YP_002397811.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15833738, 15840565, 11950925, 12730244; Product type e : enzyme
YP_002397812.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397813.1	SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals
YP_002397814.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397815.1	binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers
YP_002397816.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2404765; Product type pr : putative regulator
YP_002397817.1	uncharacterized member of the major facilitator superfamily (MFS)
YP_002397818.1	catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge
YP_002397819.1	catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine
YP_002397820.1	NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones
YP_002397821.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397822.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397823.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397824.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397825.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002397826.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002397827.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397828.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002397829.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397830.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_002397831.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 334727, 338599, 322142, 353292, 391404, 4261992, 4575979, 6765942; Product type lp : lipoprotein
YP_002397832.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397833.1	Acts with SufS to catalyze the formation of L-alanine from L-cysteine
YP_002397834.1	catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine
YP_002397835.1	with SufBC activates cysteine desulfurase SufS
YP_002397836.1	part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE
YP_002397837.1	with SufCD activates cysteine desulfurase SufS
YP_002397838.1	functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein
YP_002397839.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397840.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15808744; Product type pe : putative enzyme
YP_002397841.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11102686; Product type pe : putative enzyme
YP_002397842.1	YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function
YP_002397843.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397844.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397845.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397846.1	YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate
YP_002397847.1	catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis
YP_002397848.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16253988; Product type e : enzyme
YP_002397849.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002397850.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002397851.1	may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain
YP_002397852.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002397853.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397854.1	YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain
YP_002397855.1	May play a role in a redox process
YP_002397856.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002397857.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002397858.1	acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids
YP_002397859.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_002397860.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397861.1	tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate
YP_002397862.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15039350
YP_002397863.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397864.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397865.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12620121; Product type lp : lipoprotein
YP_002397866.1	ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell
YP_002397867.1	similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane
YP_002397868.1	with BtuD and BtuF transports vitamin B12 into the cell
YP_002397869.1	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
YP_002397870.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily
YP_002397871.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily
YP_002397873.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
YP_002397874.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93085722, 10094780, 3298224, 3542048, 6325158; Product type s : structure
YP_002397875.1	catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002397876.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397877.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 78194149, 88292964, 6235149, 6310120; Product type e : enzyme
YP_002397878.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397879.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397880.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397881.1	YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate
YP_002397882.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10760155; Product type pm : putative membrane component
YP_002397883.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397884.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9427399; Product type cp : cell process
YP_002397885.1	Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide
YP_002397886.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 20042356, 1987146, 2179047, 8121401, 9405618
YP_002397887.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20042356, 90185127, 9405618; Product type e : enzyme
YP_002397888.1	represses the celABCDF-ydjC operon involved in carbon uptake
YP_002397889.1	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake
YP_002397890.1	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake
YP_002397891.1	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake
YP_002397892.1	osmotically-inducible lipoprotein E; activator of ntr-like gene protein
YP_002397893.1	catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers
YP_002397894.1	3' incision activity; acts with UvrC
YP_002397895.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 21862596
YP_002397896.1	periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP
YP_002397897.1	catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism
YP_002397898.1	catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation
YP_002397899.1	a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH
YP_002397900.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14675764, 98361920; Product type e : enzyme
YP_002397901.1	catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate
YP_002397902.1	removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction
YP_002397903.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397904.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397905.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397906.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397907.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397908.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397909.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397910.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397911.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type m : membrane component
YP_002397912.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21101911; Product type e : enzyme
YP_002397913.1	converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer
YP_002397914.1	decatenates replicating daughter chromosomes
YP_002397915.1	catalyzes the formation of selenophosphate from selenide and ATP
YP_002397916.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397917.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397918.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397919.1	SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane
YP_002397920.1	converts asparagine to aspartate and ammonia
YP_002397921.1	catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide
YP_002397922.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397923.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397924.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002397925.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397926.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397927.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12897001; Product type pe : putative enzyme
YP_002397928.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397929.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397930.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397931.1	this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress
YP_002397932.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 775311, 94131963, 98361923, 1862091, 2124629, 2990926, 7896119, 8636984, 9298646; Product type e : enzyme
YP_002397933.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397934.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397935.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10037771, 20267815; Product type f : factor
YP_002397936.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397937.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397938.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397939.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397940.1	Evidence 6 : Doubtful CDS
YP_002397941.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397942.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002397943.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397944.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397945.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397946.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397947.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397948.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397949.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397950.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397951.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002397952.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88289400, 89053950, 93015723, 8107670; Product type e : enzyme
YP_002397953.1	Activates fatty acids by binding to coenzyme A
YP_002397954.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16079137; Product type lp : lipoprotein
YP_002397955.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397956.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002397957.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397958.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397959.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397960.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88025006, 91067712, 91302313, 96011382, 6330050, 7896119; Product type e : enzyme
YP_002397961.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7567469; Product type pe : putative enzyme
YP_002397962.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15155761, 89359152, 91056090, 93170282; Product type e : enzyme
YP_002397963.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16513732; Product type pe : putative enzyme
YP_002397964.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002397965.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87165962, 90036983, 8131846, 8676384, 9074635, 9298646; Product type t : transporter
YP_002397966.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10473571, 87165962, 90036983, 94086520, 97128775, 7811395, 8774730; Product type t : transporter
YP_002397967.1	hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel
YP_002397968.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397969.1	membrane protein YebN
YP_002397970.1	methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth
YP_002397971.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20345064, 21101802, 94293754, 12071744, 7984109, 8022261, 9298646, 9868784, 9921691; Product type f : factor
YP_002397972.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397973.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397974.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397975.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397976.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15659677, 4359651; Product type r : regulator
YP_002397977.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002397978.1	putative metalloprotease
YP_002397979.1	Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3
YP_002397980.1	affects solute and DNA transport through an unknown mechanism
YP_002397981.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397982.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397983.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397984.1	in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA
YP_002397985.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397986.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397987.1	Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins
YP_002397988.1	Evidence 6 : Doubtful CDS
YP_002397989.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397990.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002397991.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397992.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15090519, 92147649, 92156151, 94131961, 1575709, 8341603, 8505306; Product type e : enzyme
YP_002397993.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397994.1	3'-5' exonuclease activity on single or double-strand DNA
YP_002397995.1	PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues
YP_002397996.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002397997.1	secreted protein; unknown function
YP_002397998.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9368369, 99403401; Product type cp : cell process
YP_002397999.1	non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis
YP_002398000.1	catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate
YP_002398001.1	catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate
YP_002398002.1	catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate
YP_002398003.1	Represses the expression of the zwf, eda, glp and gap
YP_002398004.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_002398005.1	Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA
YP_002398006.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1732206; Product type pe : putative enzyme
YP_002398007.1	involved in transport of zinc(II) with ZnuA and C
YP_002398008.1	involved in transport of zinc(II) with ZnuA and C
YP_002398009.1	involved in transport of zinc(II) with ZnuA and C
YP_002398010.1	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
YP_002398011.1	plays an essential role in ATP-dependent branch migration of the Holliday junction
YP_002398012.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398013.1	endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity
YP_002398014.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398015.1	converts dATP to dAMP and pyrophosphate
YP_002398016.1	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
YP_002398017.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398018.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398019.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 10722621, 17220264, 9194704, 9743528; Product type e : enzyme
YP_002398020.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10722621
YP_002398021.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 10722621; Product type h : extrachromosomal origin
YP_002398022.1	Evidence 6 : Doubtful CDS
YP_002398023.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10722621; Product type h : extrachromosomal origin
YP_002398024.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10722621; Product type h : extrachromosomal origin
YP_002398025.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398026.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398027.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398028.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398029.1	Evidence 6 : Doubtful CDS
YP_002398030.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398031.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398032.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398033.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398034.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398035.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398036.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398037.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398038.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398039.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398040.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398041.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398042.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398043.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398044.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398045.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398046.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398047.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398048.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin
YP_002398049.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398050.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398051.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398052.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019562; Product type pe : putative enzyme
YP_002398053.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398054.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002398055.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398056.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398057.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398058.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398059.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398060.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398061.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398062.1	Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin
YP_002398063.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398064.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398065.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398066.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398067.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398068.1	Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin
YP_002398069.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398070.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398071.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398072.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398073.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398074.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398075.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398076.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398077.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398078.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2129559, 7984428
YP_002398079.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398080.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11746687; Product type e : enzyme
YP_002398081.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398082.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 97077292, 11004177; Product type e : enzyme
YP_002398083.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20461225, 8919859; Product type c : carrier
YP_002398084.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95362641, 7635807; Product type t : transporter
YP_002398085.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12660999; Product type pe : putative enzyme
YP_002398086.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
YP_002398087.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8002587, 1482109, 89181349
YP_002398088.1	membrane protein involved in the flagellar export apparatus
YP_002398089.1	membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export
YP_002398090.1	cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation
YP_002398091.1	chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble
YP_002398092.1	regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins
YP_002398093.1	methylates the MCP
YP_002398094.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90094243, 92165727, 6305515, 9315712; Product type r : regulator
YP_002398095.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91126073, 91296802, 91317710, 2002011, 3510184; Product type r : regulator
YP_002398096.1	chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component
YP_002398097.1	with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine
YP_002398098.1	With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine
YP_002398099.1	With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems
YP_002398100.1	with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems
YP_002398101.1	ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress
YP_002398102.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92078100, 92121128, 93302496, 8045430; Product type e : enzyme
YP_002398103.1	biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature
YP_002398104.1	Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose
YP_002398105.1	Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose
YP_002398106.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89255061, 90375534, 2445996, 326784, 326785, 6885805, 7031057, 9298646; Product type t : transporter
YP_002398107.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002398108.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002398109.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002398110.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398111.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398112.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398113.1	cytoplasmic iron storage protein
YP_002398114.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398115.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89008121, 2022620; Product type t : transporter
YP_002398116.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398117.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 381294, 7007311, 94253011, 1323047, 3003065, 8917447; Product type e : enzyme
YP_002398118.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
YP_002398119.1	in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system
YP_002398120.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3515318, 7567469
YP_002398121.1	regulates genes involved in cell division
YP_002398122.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398123.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398124.1	catalyzes the formation of pyruvate from D-cysteine
YP_002398125.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96125225, 8450713, 8774726, 9298646, 9740056; Product type t : transporter
YP_002398126.1	expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence
YP_002398127.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes
YP_002398128.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7690024; Product type s : structure
YP_002398129.1	involved in flagellin assembly
YP_002398130.1	flagellin specific chaperone
YP_002398131.1	binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family
YP_002398132.1	converts 1,4-alpha-D-glucans to maltodextrin
YP_002398133.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398134.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398135.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398136.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398137.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398138.1	Evidence 6 : Doubtful CDS
YP_002398139.1	Evidence 7 : Gene remnant
YP_002398140.1	Evidence 5 : No homology to any previously reported sequences
YP_002398141.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12270809; Product type pr : putative regulator
YP_002398142.1	DLP12 prophage; similar to PEBP/RK1P protein family in eukaryotes that inhibits MEK phosphorylation by Raf-1; crystal structure suggests similar properties but exact function is unknown
YP_002398143.1	member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation
YP_002398144.1	forms a junction between the M-ring and FlgB during flagella biosynthesis
YP_002398145.1	the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod
YP_002398146.1	One of three proteins involved in switching the direction of the flagellar rotation
YP_002398147.1	binds to and inhibits the function of flagella specific ATPase FliI
YP_002398148.1	involved in type III protein export during flagellum assembly
YP_002398149.1	rod/hook and filament chaperone
YP_002398150.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1482109, 8631687; Product type s : structure
YP_002398151.1	interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring
YP_002398152.1	with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation
YP_002398153.1	One of three proteins involved in switching the direction of the flagellar rotation
YP_002398154.1	with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus
YP_002398155.1	FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus
YP_002398156.1	with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus
YP_002398157.1	FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus
YP_002398158.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14514676, 14766922, 20167175, 90130299, 91154130, 92048476, 9882673, 7534408; Product type r : regulator
YP_002398159.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 96324407, 7534408
YP_002398160.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398161.1	catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate
YP_002398162.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16530465; Product type pe : putative enzyme
YP_002398163.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398164.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398165.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398166.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398167.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330522, 92049708, 94049122, 10360178, 10612397, 10871403, 2527357; Product type e : enzyme
YP_002398168.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90280700, 91285397, 93367813, 2198248, 2527357; Product type e : enzyme
YP_002398169.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7567469; Product type pe : putative enzyme
YP_002398170.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398171.1	Evidence 2b : Function of strongly homologous gene; Product type pm : putative membrane component
YP_002398172.1	Hsp31 stabilizes early unfolding protein intermediates under severe heat stress
YP_002398173.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15522865; Product type rc : receptor
YP_002398174.1	induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced
YP_002398175.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398176.1	in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ
YP_002398177.1	in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme
YP_002398178.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12077457, 12480884, 12909634, 9579078
YP_002398179.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398180.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16042411; Product type pc : putative carrier
YP_002398181.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398182.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398183.1	catalyzes the conversion of chorismate to salicylate in the biosynthesis of the siderophore yersiniabactin
YP_002398184.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398185.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10231486, 11320115; Product type t : transporter
YP_002398186.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10231486, 11320115; Product type t : transporter
YP_002398187.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8930916; Product type r : regulator
YP_002398188.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15719346, 15582399, 8366034, 11927258, 9709002; Product type e : enzyme
YP_002398189.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15719346, 15582399, 11927258; Product type e : enzyme
YP_002398190.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11927258; Product type e : enzyme
YP_002398191.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398192.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9818149, 11927258, 9709002; Product type e : enzyme
YP_002398193.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7896707, 7984105; Product type rc : receptor
YP_002398194.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398195.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398196.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398197.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398198.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398199.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398200.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure
YP_002398201.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure
YP_002398202.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure
YP_002398203.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure
YP_002398204.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14731283, 15546668, 16428391
YP_002398205.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure
YP_002398206.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure
YP_002398207.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure
YP_002398208.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391; Product type ps : putative structure
YP_002398209.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 15546668, 16428391, 2370849, 2233252; Product type ps : putative structure
YP_002398210.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398211.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 8029323, 7891554, 8812785, 1569033; Product type h : extrachromosomal origin
YP_002398212.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14731283
YP_002398213.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 10940031; Product type h : extrachromosomal origin
YP_002398214.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 10940031, 11251827; Product type h : extrachromosomal origin
YP_002398215.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14731283, 10686096; Product type pc : putative carrier
YP_002398216.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 7737514, 1718819, 15126494, 7737514; Product type pe : putative enzyme
YP_002398217.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398218.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398219.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398220.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8412658; Product type pe : putative enzyme
YP_002398221.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15659678; Product type f : factor
YP_002398222.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 5332864, 9524262; Product type t : transporter
YP_002398223.1	Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile
YP_002398224.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398225.1	Evidence 6 : Doubtful CDS
YP_002398226.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16042411; Product type pt : putative transporter
YP_002398227.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398228.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398229.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002398230.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398231.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398232.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398233.1	Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin
YP_002398234.1	Evidence 5 : No homology to any previously reported sequences
YP_002398235.1	Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin
YP_002398236.1	Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin
YP_002398237.1	Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin
YP_002398238.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398239.1	Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin
YP_002398240.1	Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin
YP_002398241.1	Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin
YP_002398242.1	Evidence 6 : Doubtful CDS; Product type h : extrachromosomal origin
YP_002398243.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398244.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398245.1	Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin
YP_002398246.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398247.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398248.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398249.1	Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin
YP_002398250.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398251.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89056689, 94335643, 95267838, 95286558, 99355427, 2404280, 11298273; Product type r : regulator
YP_002398252.1	Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin
YP_002398253.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398254.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398255.1	Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin
YP_002398256.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398257.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398258.1	LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB
YP_002398259.1	Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation
YP_002398260.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9298646
YP_002398261.1	catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole
YP_002398262.1	catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole
YP_002398263.1	catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP
YP_002398264.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398265.1	Evidence 7 : Gene remnant; Product type pe : putative enzyme
YP_002398266.1	Evidence 7 : Gene remnant
YP_002398267.1	Evidence 6 : Doubtful CDS
YP_002398268.1	Evidence 6 : Doubtful CDS
YP_002398269.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398270.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398271.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398272.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398273.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398274.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398275.1	Evidence 5 : No homology to any previously reported sequences
YP_002398276.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7519596; Product type h : extrachromosomal origin
YP_002398277.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11053371; Product type pf : putative factor
YP_002398278.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398279.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14594833; Product type h : extrachromosomal origin
YP_002398280.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398281.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398282.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398283.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11850398, 9442027, 8709849; Product type r : regulator
YP_002398284.1	removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains
YP_002398285.1	Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates
YP_002398286.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398287.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398288.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398289.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002398290.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398292.1	long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors
YP_002398293.1	catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer
YP_002398294.1	catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis
YP_002398295.1	catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate
YP_002398296.1	with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide
YP_002398297.1	catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide
YP_002398298.1	catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase
YP_002398299.1	catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis
YP_002398300.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98241528; Product type r : regulator
YP_002398301.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9150218, 96326333; Product type e : enzyme
YP_002398302.1	catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate
YP_002398303.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002398304.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398305.1	Evidence 5 : No homology to any previously reported sequences
YP_002398306.1	Evidence 5 : No homology to any previously reported sequences
YP_002398307.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002398308.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398309.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11882717, 1906926, 8393871, 9182537, 11487587, 10508782; Product type e : enzyme
YP_002398310.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89274199, 92253563, 92338916, 3022232, 6301942, 8564363, 8611559, 893113; Product type e : enzyme
YP_002398311.1	together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose
YP_002398312.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11976290; Product type e : enzyme
YP_002398313.1	WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid
YP_002398314.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333; Product type pe : putative enzyme
YP_002398315.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333, 8759852, 11004393; Product type pe : putative enzyme
YP_002398316.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 8759852; Product type pt : putative transporter
YP_002398317.1	WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid
YP_002398318.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106949, 96326333, 7815923, 8759852; Product type e : enzyme
YP_002398319.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82100097, 85006781, 92048476, 93122523, 96326333, 7815923, 8759852; Product type e : enzyme
YP_002398320.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15670885, 96326333; Product type pe : putative enzyme
YP_002398321.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 10913267, 7592609, 7815923, 8759852; Product type e : enzyme
YP_002398322.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 98132401, 9862812, 7815923, 8759852, 9473059; Product type e : enzyme
YP_002398323.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20139699, 97400210, 10673432, 7815923, 8759852, 9257704, 14299611; Product type e : enzyme
YP_002398324.1	acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit)
YP_002398325.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11371548, 96326333, 8759852; Product type pe : putative enzyme
YP_002398326.1	essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance
YP_002398327.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333; Product type pe : putative enzyme
YP_002398328.1	acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium
YP_002398329.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333; Product type pe : putative enzyme
YP_002398330.1	Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide)
YP_002398331.1	Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis
YP_002398332.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 15090537, 96326333, 8759852, 8763957; Product type lp : lipoprotein
YP_002398333.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002398334.1	YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs
YP_002398335.1	Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis
YP_002398336.1	functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor
YP_002398337.1	contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction
YP_002398338.1	inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine
YP_002398339.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 6094528, 7940673, 7984428; Product type pf : putative factor
YP_002398340.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398341.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398342.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398343.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398344.1	Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate
YP_002398345.1	Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate
YP_002398346.1	Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate
YP_002398347.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12107134, 21450803, 8282725; Product type t : transporter
YP_002398348.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94110256, 8282725; Product type r : regulator
YP_002398349.1	response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport
YP_002398350.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398351.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398352.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398353.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398354.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398355.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398356.1	in E. coli K-12 this is in prophage P2 remnant
YP_002398357.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3458177; Product type h : extrachromosomal origin
YP_002398358.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12426340; Product type h : extrachromosomal origin
YP_002398359.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398360.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398361.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398362.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398363.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398364.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398365.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398366.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398367.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398368.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398369.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398370.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398371.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398372.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398373.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398374.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002398375.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002398376.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398377.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398378.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002398379.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398380.1	catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine
YP_002398381.1	catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP
YP_002398382.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398383.1	membrane protein conferring nickel and cobalt resistance
YP_002398384.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398385.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002398386.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398387.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002398388.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002398389.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398390.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91080852, 15601724, 2259334; Product type t : transporter
YP_002398391.1	methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content
YP_002398392.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2156810; Product type pr : putative regulator
YP_002398393.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398394.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398395.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16428726; Product type pf : putative factor
YP_002398396.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398397.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398398.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398399.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type lp : lipoprotein
YP_002398400.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398401.1	unknown function; when overproduced it confers drug-resistance
YP_002398402.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15522865, 15322361; Product type rc : receptor
YP_002398403.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398404.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 10722621, 17220264; Product type h : extrachromosomal origin
YP_002398405.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10722621
YP_002398406.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 10722621; Product type h : extrachromosomal origin
YP_002398407.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10722621; Product type h : extrachromosomal origin
YP_002398408.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398409.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398410.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398411.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398412.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002398413.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7999761, 10426954; Product type pr : putative regulator
YP_002398414.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398415.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398416.1	Evidence 2b : Function of strongly homologous gene; Product type t : transporter
YP_002398417.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 11686382, 11282477, 9562894, 8878031; Product type f : factor
YP_002398418.1	Evidence 2b : Function of strongly homologous gene; Product type f : factor
YP_002398419.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398420.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398421.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002398422.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002398423.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398424.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002398425.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002398426.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398427.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398428.1	Evidence 2b : Function of strongly homologous gene; Product type s : structure
YP_002398429.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398430.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398431.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398432.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398433.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398434.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398435.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398436.1	Evidence 6 : Doubtful CDS; Product type h : extrachromosomal origin
YP_002398437.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398438.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398439.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398440.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398441.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin
YP_002398442.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398443.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002398444.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398445.1	Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin
YP_002398446.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398447.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398448.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398449.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398450.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398451.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398452.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398453.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398454.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398455.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398456.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398457.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398458.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398459.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398460.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398461.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398462.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398463.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398464.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin
YP_002398465.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 375198; Product type h : extrachromosomal origin
YP_002398466.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398467.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398468.1	Evidence 5 : No homology to any previously reported sequences
YP_002398469.1	Evidence 5 : No homology to any previously reported sequences
YP_002398470.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9501914; Product type h : extrachromosomal origin
YP_002398471.1	Evidence 5 : No homology to any previously reported sequences
YP_002398472.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398473.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398474.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 6458018, 6221115; Product type h : extrachromosomal origin
YP_002398475.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398476.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398477.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398478.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398479.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398480.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398481.1	Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
YP_002398482.1	Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
YP_002398483.1	Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
YP_002398484.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398485.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398486.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398487.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11489123; Product type r : regulator
YP_002398488.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398489.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398490.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398491.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15251200; Product type pt : putative transporter
YP_002398492.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96303506; Product type e : enzyme
YP_002398493.1	component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent
YP_002398494.1	specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7
YP_002398495.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398496.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398497.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398498.1	may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride
YP_002398499.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398500.1	Evidence 5 : No homology to any previously reported sequences
YP_002398501.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22095566; Product type e : enzyme
YP_002398502.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398503.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398504.1	Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis
YP_002398505.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 96125233, 1567863, 8550448
YP_002398506.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398507.1	function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain
YP_002398508.1	catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines
YP_002398509.1	ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex
YP_002398510.1	with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains
YP_002398511.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87286407, 92049246, 1719366, 3057628, 3302609, 3600760, 6340108, 6885805, 7012152, 9298646; Product type t : transporter
YP_002398512.1	negative regulator of the mglBAC operon for galactose utilization
YP_002398513.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398514.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398515.1	involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer
YP_002398516.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398517.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16567800; Product type e : enzyme
YP_002398518.1	Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein
YP_002398519.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92250419, 94252996, 1315732, 7551055; Product type t : transporter
YP_002398520.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12400704, 1315732; Product type pr : putative regulator
YP_002398521.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398522.1	Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues
YP_002398523.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398524.1	Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively
YP_002398525.1	activator of nucleoside metabolism
YP_002398526.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398527.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398528.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398529.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
YP_002398530.1	converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers
YP_002398531.1	phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr
YP_002398532.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398533.1	Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein
YP_002398534.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398535.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398536.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15778224; Product type e : enzyme
YP_002398537.1	by similarity, Spr seems to have peptidase activity; involved in thermoresistance
YP_002398538.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398539.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398540.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398541.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398542.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398543.1	Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance
YP_002398544.1	catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA
YP_002398545.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398546.1	the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response
YP_002398547.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99296598, 10368163; Product type f : factor
YP_002398548.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398549.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398550.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398551.1	Evidence 6 : Doubtful CDS
YP_002398552.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398553.1	Evidence 6 : Doubtful CDS; Product type h : extrachromosomal origin
YP_002398554.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398555.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8491703; Product type h : extrachromosomal origin
YP_002398556.1	Evidence 5 : No homology to any previously reported sequences
YP_002398557.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398558.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398559.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398560.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398561.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398562.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398563.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398564.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398565.1	Evidence 6 : Doubtful CDS
YP_002398566.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398567.1	nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes
YP_002398568.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 11756453, 12196152, 87260957, 91194558, 95362656, 9914305, 7635817; Product type pe : putative enzyme
YP_002398569.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 9716493, 9770295, 11256948, 11350062, 11843181, 7635817, 9537397; Product type e : enzyme
YP_002398570.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 11756453, 12196152, 87260957, 8842153, 91194558, 95362656, 9716493, 7635817; Product type e : enzyme
YP_002398571.1	CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane
YP_002398572.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 95362656, 9716493, 7635817; Product type f : factor
YP_002398573.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 14532274, 21413853, 95362656, 7635817; Product type t : transporter
YP_002398574.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 95362656, 9716493, 7635817; Product type t : transporter
YP_002398575.1	ATP-binding protein; required for proper cytochrome c maturation
YP_002398576.1	with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone
YP_002398577.1	small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA
YP_002398578.1	part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA
YP_002398579.1	part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway
YP_002398580.1	periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC
YP_002398581.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96228696, 99395037; Product type f : factor
YP_002398582.1	Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA.
YP_002398583.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398584.1	serine protease inhibitor, inhibits trypsin and other proteases
YP_002398585.1	malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate
YP_002398586.1	efflux pump for the antibacterial peptide microcin J25
YP_002398587.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12226668, 12517444, 12862460, 14527653, 87057220, 88151899, 92017669, 3536913, 3887409, 7928996; Product type e : enzyme
YP_002398588.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91073391, 93272965, 94252990; Product type r : regulator
YP_002398589.1	catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway
YP_002398590.1	allows for ions and hydrophilic solutes to cross the outer membrane
YP_002398591.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11758943, 12864862, 21206231, 2404948, 7984428; Product type r : regulator
YP_002398592.1	two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF
YP_002398593.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11758943, 12864862, 14651646, 20032358, 21450811, 88227838, 90130299, 92048476, 9209051, 2404948, 8366025; Product type r : regulator
YP_002398594.1	with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism
YP_002398595.1	with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism
YP_002398596.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type c : carrier
YP_002398597.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type c : carrier
YP_002398598.1	Evidence 6 : Doubtful CDS
YP_002398599.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type t : transporter
YP_002398600.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type c : carrier
YP_002398601.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398602.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398603.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002398604.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398605.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398606.1	negatively supercoils closed circular double-stranded DNA
YP_002398607.1	Involved in ubiquinone biosynthesis
YP_002398608.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15659678; Product type f : factor
YP_002398609.1	Catalyzes the rate-limiting step in dNTP synthesis
YP_002398610.1	B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA
YP_002398611.1	plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases
YP_002398612.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 92165728, 1537798, 6087316
YP_002398613.1	hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic
YP_002398614.1	catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell
YP_002398615.1	anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor
YP_002398616.1	sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters
YP_002398617.1	anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate
YP_002398618.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398619.1	Evidence 7 : Gene remnant
YP_002398620.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12454498, 16511168, 8550403; Product type pe : putative enzyme
YP_002398621.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398622.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398623.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002398624.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398625.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398626.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16430214; Product type pe : putative enzyme
YP_002398627.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398628.1	catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose
YP_002398629.1	catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate
YP_002398630.1	Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains
YP_002398631.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398632.1	catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A
YP_002398633.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398634.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398635.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96015440, 15569938; Product type pt : putative transporter
YP_002398636.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96186953, 8626063; Product type e : enzyme
YP_002398637.1	catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate
YP_002398638.1	catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA
YP_002398639.1	catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA
YP_002398640.1	SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis
YP_002398641.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9150206, 96140724, 2666397, 7984428, 8549818, 8764478; Product type e : enzyme
YP_002398642.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398643.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398644.1	member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions
YP_002398645.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398646.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398647.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398648.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002398649.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002398650.1	Catalyzes the transfer of electrons from NADH to ubiquinone
YP_002398651.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002398652.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002398653.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002398654.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002398655.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002398656.1	shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase
YP_002398657.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002398658.1	NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms
YP_002398659.1	The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen
YP_002398660.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002398661.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12123461, 9882671, 7565112; Product type r : regulator
YP_002398662.1	broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor
YP_002398663.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15489502; Product type e : enzyme
YP_002398664.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398665.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398666.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398667.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398668.1	AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA
YP_002398669.1	catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate
YP_002398670.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pc : putative carrier
YP_002398671.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16430214; Product type pe : putative enzyme
YP_002398672.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398673.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398674.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398675.1	catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate
YP_002398676.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pe : putative enzyme
YP_002398677.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398678.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434, 3313284, 91060556; Product type t : transporter
YP_002398679.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434, 3313284; Product type t : transporter
YP_002398680.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434; Product type t : transporter
YP_002398681.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434, 6449635, 8161536, 9298646, 9600841, 9740056; Product type t : transporter
YP_002398682.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4583243, 87308226, 3040734, 9298646; Product type t : transporter
YP_002398683.1	catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate
YP_002398684.1	Catalyzes first step of the de novo purine nucleotide biosynthetic pathway
YP_002398685.1	membrane protein required for colicin V production
YP_002398686.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3040734
YP_002398687.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3040739, 91112811, 92041808, 1989505, 3040734; Product type e : enzyme
YP_002398688.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits
YP_002398689.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3029016, 3040734, 7678242; Product type pm : putative membrane component
YP_002398690.1	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability
YP_002398691.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 92380957, 92380982, 93123150, 2681152, 2991861, 3029016; Product type pe : putative enzyme
YP_002398692.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90036695, 91035267, 2681152, 2991861, 3029016; Product type e : enzyme
YP_002398693.1	in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein
YP_002398694.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398695.1	FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP
YP_002398696.1	catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules
YP_002398697.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398698.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398699.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398700.1	D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm
YP_002398701.1	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis
YP_002398702.1	involved in methylation of ribosomal protein L3
YP_002398703.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398704.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398705.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002398706.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002398707.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002398708.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002398709.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002398710.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002398711.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10089421, 20200300, 9489669; Product type e : enzyme
YP_002398712.1	multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate
YP_002398713.1	FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth
YP_002398714.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398715.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15178802, 2840553, 3286621, 91100327, 1987139, 9119048; Product type t : transporter
YP_002398716.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8145644, 15352239; Product type lp : lipoprotein
YP_002398717.1	Evidence 6 : Doubtful CDS
YP_002398718.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398719.1	regulates the synthesis and expression of the dsdXA operon and dadA gene
YP_002398720.1	member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function
YP_002398721.1	catalyzes the formation of pyruvate from serine
YP_002398722.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20378313; Product type pt : putative transporter
YP_002398723.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20378313; Product type t : transporter
YP_002398724.1	response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance
YP_002398725.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14523115, 93173621, 9501520, 10923791, 1289796, 8125343, 9535079; Product type r : regulator
YP_002398726.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398727.1	member of the AEC family of auxin efflux transporters; unknown function
YP_002398728.1	catalyzes the formation of formyl-CoA from oxalyl-CoA
YP_002398729.1	catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA
YP_002398730.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11157960
YP_002398731.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15183873; Product type lp : lipoprotein
YP_002398732.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14727089; Product type pm : putative membrane component
YP_002398733.1	Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock
YP_002398734.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398735.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15522865; Product type prc : putative receptor
YP_002398736.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15522865; Product type pr : putative regulator
YP_002398737.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002398738.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398739.1	metalloprotein
YP_002398740.1	Xaa-Pro aminopeptidase; limited methionine aminopeptidase
YP_002398741.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398742.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398743.1	catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate
YP_002398744.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398745.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398746.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20177822, 20305051, 10712688, 10844693; Product type t : transporter
YP_002398747.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 374403, 8022285, 7007808, 827549, 4563236, 1512211; Product type t : transporter
YP_002398748.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002398749.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002398750.1	Evidence 6 : Doubtful CDS
YP_002398751.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002398752.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002398753.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
YP_002398754.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10400599, 7007808, 2201776, 7559336; Product type r : regulator
YP_002398755.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96032385, 7559336; Product type t : transporter
YP_002398756.1	catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation
YP_002398757.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002398758.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002398759.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002398760.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398761.1	this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB
YP_002398762.1	interacts with cell division protein FitsZ and may be required to anchor septal ring structure
YP_002398763.1	putative role in sulfur assimilation
YP_002398764.1	CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis
YP_002398765.1	Evidence 1b : Function experimentally demonstrated in the studied species; Product type t : transporter
YP_002398766.1	Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system
YP_002398767.1	functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose
YP_002398768.1	catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal
YP_002398769.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398770.1	catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide
YP_002398771.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202710, 90264334, 2188958, 7665461; Product type t : transporter
YP_002398772.1	Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import
YP_002398773.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264334, 2188958; Product type t : transporter
YP_002398774.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264335, 2188959, 9298646; Product type t : transporter
YP_002398775.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 97385354, 2188959, 7984428, 9241368; Product type pe : putative enzyme
YP_002398776.1	catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway
YP_002398777.1	belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component
YP_002398778.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398779.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12900013, 7764507
YP_002398780.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398781.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398782.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21348478, 6137479, 87242501, 1903834, 8300522; Product type e : enzyme
YP_002398783.1	catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis
YP_002398784.1	activates the transcription of the ethanolamine utilization operon
YP_002398785.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10464203; Product type ps : putative structure
YP_002398786.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : putative structure
YP_002398787.1	catalyzes the formation of acetaldehyde from ethanolamine
YP_002398788.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3905806, 10464203; Product type e : enzyme
YP_002398789.1	ethanolamine utilization protein EutA
YP_002398790.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7868611, 10464203; Product type pt : putative transporter
YP_002398791.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : putative enzyme
YP_002398792.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pf : putative factor
YP_002398793.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : putative enzyme
YP_002398794.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : putative structure
YP_002398795.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : putative structure
YP_002398796.1	in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta
YP_002398797.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : putative enzyme
YP_002398798.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10464203
YP_002398799.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : putative enzyme
YP_002398800.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : putative structure
YP_002398801.1	NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate
YP_002398802.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90230300; Product type e : enzyme
YP_002398803.1	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase
YP_002398804.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398805.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398806.1	unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic)
YP_002398807.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92374842, 1508040, 1528845; Product type r : regulator
YP_002398808.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12426336, 20158894, 21450803, 79216220, 10692383, 1644752; Product type t : transporter
YP_002398809.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398810.1	dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.
YP_002398811.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398812.1	Displays esterase activity toward palmitoyl-CoA and pNP-butyrate
YP_002398813.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398814.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398815.1	catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase
YP_002398816.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91358331, 1885529, 2120198; Product type lp : lipoprotein
YP_002398817.1	catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis
YP_002398818.1	negative transcriptional regulator of the gcvTHP operon
YP_002398819.1	bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine
YP_002398820.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398821.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398822.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398823.1	controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP
YP_002398824.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8332529, 7721693; Product type t : transporter
YP_002398825.1	Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate
YP_002398826.1	catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis
YP_002398827.1	glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate
YP_002398828.1	catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate
YP_002398829.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93107072, 94025037, 94165003, 8212131, 8380170; Product type e : enzyme
YP_002398830.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398831.1	Evidence 6 : Doubtful CDS
YP_002398832.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002398833.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398834.1	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
YP_002398835.1	catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate
YP_002398836.1	bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides
YP_002398837.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398838.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002398839.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002398840.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12540539; Product type pm : putative membrane component
YP_002398841.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8500884, 3304658, 12540539; Product type pf : putative factor
YP_002398842.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398843.1	EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
YP_002398844.1	with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis
YP_002398845.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398846.1	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG
YP_002398847.1	catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis
YP_002398848.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398849.1	23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance
YP_002398850.1	catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate
YP_002398851.1	penicillin-insensitive transglycosylase/transpeptidase
YP_002398852.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398853.1	catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds
YP_002398854.1	enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I
YP_002398855.1	catalyzes the removal of an N-terminal amino acid from a peptide or arylamide
YP_002398856.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10393315; Product type pf : putative factor
YP_002398857.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10393315, 20013001, 92283811, 94181532, 11551196, 1317854, 4375562, 8300516; Product type c : carrier
YP_002398858.1	involved in the maturation of iron-sulfur cluster-containing proteins
YP_002398859.1	J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins
YP_002398860.1	forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein
YP_002398861.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10393315, 11994302, 15153099; Product type f : factor
YP_002398862.1	catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis
YP_002398863.1	regulates the expression of the iscRSUA operon
YP_002398864.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10393315; Product type pe : putative enzyme
YP_002398865.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6389495, 90202735, 95095968, 10747806, 2138605, 8002619; Product type e : enzyme
YP_002398866.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398867.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95020540, 96154950; Product type cp : cell process
YP_002398868.1	putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters
YP_002398869.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398870.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398871.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398872.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398873.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398874.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002398875.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pt : putative transporter
YP_002398876.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398877.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002398878.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
YP_002398879.1	flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine
YP_002398880.1	indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA
YP_002398881.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8226691, 8412694; Product type pr : putative regulator
YP_002398882.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398883.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002398884.1	catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis
YP_002398885.1	YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function
YP_002398886.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12110595; Product type e : enzyme
YP_002398887.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398888.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002398889.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 8765743, 8880900; Product type c : carrier
YP_002398890.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398891.1	Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids
YP_002398892.1	involved in the de novo synthesis of pyridoxine (Vitamin B6)
YP_002398893.1	involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA
YP_002398894.1	Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome
YP_002398895.1	cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity
YP_002398896.1	catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins
YP_002398897.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
YP_002398898.1	involved in the reduction of the SoxR iron-sulfur cluster
YP_002398899.1	periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP
YP_002398900.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9159522, 97303092, 99431977, 7768826; Product type f : factor
YP_002398901.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response
YP_002398902.1	catalyzes the formation of oxaloacetate from L-aspartate
YP_002398903.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398904.1	facilitates an early step in the assembly of the 50S subunit of the ribosome
YP_002398905.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002398906.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12562784; Product type t : transporter
YP_002398907.1	stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit
YP_002398908.1	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YP_002398909.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002398910.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398911.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12952960, 9388228, 99175138, 10644706; Product type c : carrier
YP_002398912.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398913.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002398914.1	catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome
YP_002398915.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398916.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91219460, 1709493, 2053984, 2118499, 2190187, 8419306; Product type t : transporter
YP_002398917.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002398918.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002398919.1	Evidence 7 : Gene remnant; Product type pe : putative enzyme
YP_002398920.1	Evidence 7 : Gene remnant
YP_002398921.1	Evidence 7 : Gene remnant; Product type pe : putative enzyme
YP_002398922.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002398923.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14550559, 14640692, 91294166, 93015925, 93388583, 99428468; Product type f : factor
YP_002398924.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1906060, 2066329
YP_002398925.1	responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA
YP_002398926.1	with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline
YP_002398927.1	associated with 30S ribosomal subunit; interferes with translation elongation
YP_002398929.1	catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis
YP_002398930.1	catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis
YP_002398931.1	catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive
YP_002398932.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6396419
YP_002398933.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398934.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002398935.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96032391; Product type pm : putative membrane component
YP_002398936.1	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
YP_002398937.1	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
YP_002398938.1	Essential for efficient processing of 16S rRNA
YP_002398939.1	binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity
YP_002398940.1	with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins
YP_002398941.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398942.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002398943.1	with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor
YP_002398944.1	catalyzes the phosphorylation of NAD to NADP
YP_002398945.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87259985, 91355307, 95058623, 3037486; Product type cp : cell process
YP_002398946.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 2045357; Product type lp : lipoprotein
YP_002398947.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398948.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398949.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
YP_002398950.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398951.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398952.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398953.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398954.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398955.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398956.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398957.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3891522, 3894006, 6310572; Product type h : extrachromosomal origin
YP_002398958.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398959.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002398960.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398961.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398962.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398963.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398964.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398965.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398966.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398967.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398968.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398969.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398970.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398971.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398972.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398973.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398974.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398975.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398976.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398977.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398978.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398979.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398980.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398981.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398982.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398983.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002398984.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398985.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398986.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002398987.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002398988.1	Evidence 5 : No homology to any previously reported sequences
YP_002398989.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398990.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398991.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002398992.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398993.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002398994.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398995.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002398996.1	Evidence 5 : No homology to any previously reported sequences
YP_002398997.1	in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution
YP_002398998.1	catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate
YP_002398999.1	catalyzes the formation of succinate from succinate semialdehyde; NADP dependent
YP_002399000.1	catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate
YP_002399001.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94127927, 9685361, 8297211; Product type t : transporter
YP_002399002.1	regulator of gab gene expression
YP_002399003.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399004.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399005.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399006.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pe : putative enzyme
YP_002399007.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20485613, 93126121, 9643551, 98132400, 99415935, 1480493, 7961433; Product type r : regulator
YP_002399008.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399009.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 7961433
YP_002399010.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399011.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399012.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399013.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9218434, 11441020, 8820648; Product type pc : putative carrier
YP_002399014.1	in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF
YP_002399015.1	Catalyzes the rate-limiting step in dNTP synthesis
YP_002399016.1	B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE
YP_002399017.1	with ProWX is involved in the high-affinity uptake of glycine betaine
YP_002399018.1	with ProVX is involved in the high-affinity uptake of glycine betaine
YP_002399019.1	with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine
YP_002399020.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16000740; Product type pt : putative transporter
YP_002399021.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399022.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399023.1	DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB
YP_002399024.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803, 93285984, 94262163, 1409590, 8203018; Product type t : transporter
YP_002399025.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803, 93285984, 94262163, 1409590; Product type t : transporter
YP_002399026.1	catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2
YP_002399027.1	involved in the first step of glutathione biosynthesis
YP_002399028.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399029.1	YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent
YP_002399030.1	affects carbohydrate metabolism; has regulatory role in many processes
YP_002399031.1	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002399032.1	binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities
YP_002399033.1	catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs
YP_002399034.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399035.1	membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan
YP_002399036.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87194727, 1334233, 3553176; Product type t : transporter
YP_002399037.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1100602, 3553176; Product type t : transporter
YP_002399038.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
YP_002399039.1	catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate
YP_002399040.1	regulator for glucitol utilization
YP_002399041.1	regulates genes involved in glucitol utilization
YP_002399042.1	catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate
YP_002399043.1	Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon
YP_002399044.1	detoxifies nitric oxide using NADH
YP_002399045.1	catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase
YP_002399046.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12377778, 92255260, 8661925; Product type e : enzyme
YP_002399047.1	involved in electron transport from formate to hydrogen
YP_002399048.1	Evidence 5 : No homology to any previously reported sequences
YP_002399049.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399050.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399051.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399052.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399053.1	involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE
YP_002399054.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92215587, 92326636, 1625581, 2187144, 7851435; Product type f : factor
YP_002399055.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90251163, 92215587, 92326636, 2187144; Product type e : enzyme
YP_002399056.1	electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate
YP_002399057.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92215587, 92326636, 94170785, 2187144, 8125094; Product type e : enzyme
YP_002399058.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90251163, 92215587, 92326636; Product type m : membrane component
YP_002399059.1	catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3)
YP_002399060.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90251163, 92215587, 92326636, 2187144; Product type c : carrier
YP_002399061.1	regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon
YP_002399062.1	plays a role in hydrogenase nickel cofactor insertion
YP_002399063.1	GTP hydrolase involved in nickel liganding into hydrogenases
YP_002399064.1	HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase
YP_002399065.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91194542, 92255260, 1849603; Product type f : factor
YP_002399066.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91194542, 9485446, 1849603; Product type e : enzyme
YP_002399067.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20307603, 21557168, 90368529, 92140045, 94018617, 2118503, 2280686; Product type r : regulator
YP_002399068.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399069.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399070.1	This protein performs the mismatch recognition step during the DNA repair process
YP_002399071.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9130712; Product type e : enzyme
YP_002399072.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399073.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399074.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11520622
YP_002399075.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399076.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399077.1	member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function
YP_002399078.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399079.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9694845; Product type pf : putative factor
YP_002399080.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses
YP_002399081.1	outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus
YP_002399082.1	catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins
YP_002399083.1	catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate
YP_002399084.1	catalyzes the modification of U13 in tRNA(Glu)
YP_002399085.1	catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate
YP_002399086.1	4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers
YP_002399087.1	forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein
YP_002399088.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399089.1	converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis
YP_002399090.1	may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ
YP_002399091.1	with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP
YP_002399092.1	catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3
YP_002399093.1	Evidence 1b : Function experimentally demonstrated in the studied species; Product type pm : putative membrane component
YP_002399094.1	catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite
YP_002399095.1	hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide
YP_002399096.1	catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity
YP_002399097.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12123838; Product type e : enzyme
YP_002399098.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399099.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002399100.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399101.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002399102.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002399103.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399104.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399105.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399106.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399107.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399108.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399109.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399110.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399111.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399112.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399113.1	Evidence 6 : Doubtful CDS
YP_002399114.1	enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis
YP_002399115.1	CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
YP_002399116.1	functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era
YP_002399117.1	MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system
YP_002399118.1	part of the MazF-MazE toxin-antitoxin system; conteracts MazF
YP_002399119.1	(p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP
YP_002399120.1	in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]
YP_002399121.1	part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system
YP_002399122.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20233700, 9772162, 10762278, 13971911; Product type e : enzyme
YP_002399123.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 9772162; Product type e : enzyme
YP_002399124.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10762278; Product type pt : putative transporter
YP_002399125.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
YP_002399126.1	catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp
YP_002399127.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399128.1	putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function
YP_002399129.1	catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis
YP_002399130.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399131.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8752353, 8026499; Product type pt : putative transporter
YP_002399132.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91193203, 93215657, 8385012; Product type e : enzyme
YP_002399133.1	has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups
YP_002399134.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88142551, 89291720, 2553671, 2661535, 2664711, 8385012; Product type e : enzyme
YP_002399135.1	catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate
YP_002399136.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88142551, 90036697, 2553671, 2664711, 7783647; Product type t : transporter
YP_002399137.1	catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose
YP_002399138.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88142551, 90036697, 2664711, 13905785; Product type e : enzyme
YP_002399139.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15060078, 12738765, 80049526, 2664711; Product type e : enzyme
YP_002399140.1	regulates expression of genes involved in L-fucose utilization
YP_002399141.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 21188420, 7704273; Product type pe : putative enzyme
YP_002399142.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 7704273; Product type pm : putative membrane component
YP_002399143.1	Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence
YP_002399144.1	Evidence 6 : Doubtful CDS
YP_002399145.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399146.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15148362, 9278392, 10739946, 10829016; Product type e : enzyme
YP_002399147.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002399148.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399149.1	membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues
YP_002399150.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002399151.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399152.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399153.1	Evidence 2b : Function of strongly homologous gene; Product type t : transporter
YP_002399154.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399155.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12787347, 21348478; Product type e : enzyme
YP_002399156.1	catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis
YP_002399157.1	helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity
YP_002399158.1	helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity
YP_002399159.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91193232, 1570301, 3308636, 3534791, 3537960, 8099278; Product type e : enzyme
YP_002399160.1	catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination
YP_002399161.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 7934814; Product type e : enzyme
YP_002399162.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399163.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 7934814; Product type e : enzyme
YP_002399164.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 7934814; Product type e : enzyme
YP_002399165.1	ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived
YP_002399166.1	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein
YP_002399167.1	member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr
YP_002399168.1	hydrolyzes diadenosine polyphosphate
YP_002399169.1	MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair
YP_002399170.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399171.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399172.1	complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH
YP_002399173.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8300626; Product type pm : putative membrane component
YP_002399174.1	Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1
YP_002399175.1	controls transcription of galETKM
YP_002399176.1	catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding
YP_002399177.1	activates the transcription of the lysA gene encoding diaminopimelate decarboxylase
YP_002399178.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15135544; Product type pe : putative enzyme
YP_002399179.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7030324, 90239116, 91154204, 2836407, 3543693, 6319708; Product type t : transporter
YP_002399180.1	catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate
YP_002399181.1	4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
YP_002399182.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis
YP_002399183.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399184.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002399185.1	Evidence 5 : No homology to any previously reported sequences
YP_002399186.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399187.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399188.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399189.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002399190.1	Evidence 5 : No homology to any previously reported sequences
YP_002399191.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002399192.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399193.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399194.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399195.1	Evidence 5 : No homology to any previously reported sequences
YP_002399196.1	Evidence 5 : No homology to any previously reported sequences
YP_002399197.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399198.1	Evidence 5 : No homology to any previously reported sequences
YP_002399199.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002399200.1	Evidence 6 : Doubtful CDS
YP_002399201.1	Evidence 6 : Doubtful CDS
YP_002399202.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002399203.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15150243; Product type r : regulator
YP_002399204.1	putative molybdenum cofactor-binding protein; participates in purine salvage
YP_002399205.1	FAD-binding subunit; with XdhA and XdhC participates in purine salvage
YP_002399206.1	iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage
YP_002399207.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399208.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399209.1	catalyzes the formation of pyruvate from 2,3-diaminopropionate
YP_002399210.1	Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases
YP_002399211.1	catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position
YP_002399212.1	catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP
YP_002399213.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399214.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399215.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399216.1	with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase
YP_002399217.1	in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS
YP_002399218.1	with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain
YP_002399219.1	with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration
YP_002399220.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20372655, 98213740; Product type pt : putative transporter
YP_002399221.1	Catalyzes the deamination of guanine
YP_002399222.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399223.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002399224.1	unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic)
YP_002399225.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 9098051; Product type t : transporter
YP_002399226.1	catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate
YP_002399227.1	class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1
YP_002399228.1	recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1
YP_002399229.1	5'-3' single-stranded-DNA-specific exonuclease
YP_002399230.1	DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity
YP_002399231.1	site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs
YP_002399232.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic
YP_002399233.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399234.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399235.1	physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator
YP_002399236.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002399237.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399238.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87222180, 88297127, 92334140; Product type e : enzyme
YP_002399239.1	acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine
YP_002399240.1	part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor
YP_002399241.1	catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein
YP_002399242.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1339425; Product type pe : putative enzyme
YP_002399243.1	Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone
YP_002399244.1	exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide
YP_002399245.1	the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown
YP_002399246.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 412171; Product type cp : cell process
YP_002399247.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14727089, 2579060; Product type pe : putative enzyme
YP_002399248.1	catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate
YP_002399249.1	Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway
YP_002399250.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399251.1	specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport
YP_002399252.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399253.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399254.1	Involved in the export of arginine
YP_002399255.1	participates in the regulation of osmotic pressure changes within the cel
YP_002399256.1	catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate
YP_002399257.1	Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway
YP_002399258.1	NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate
YP_002399259.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399260.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399261.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399262.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399263.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399264.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399265.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399266.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399267.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 8353127; Product type t : transporter
YP_002399268.1	TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein
YP_002399269.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399270.1	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase
YP_002399271.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1310091; Product type pe : putative enzyme
YP_002399272.1	catalyzes the formation of putrescine from agmatine
YP_002399273.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399274.1	catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis
YP_002399275.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399276.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399277.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399278.1	catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
YP_002399279.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9182541; Product type t : transporter
YP_002399280.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 7984428, 8113204
YP_002399281.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 72060411, 92335461, 4955462, 7867949, 8113204; Product type e : enzyme
YP_002399282.1	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase
YP_002399283.1	catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione
YP_002399284.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399285.1	similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function
YP_002399286.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1676385; Product type t : transporter
YP_002399287.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399288.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399289.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12975589
YP_002399290.1	HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine
YP_002399291.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_002399292.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399293.1	catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis
YP_002399294.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11274153
YP_002399295.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399296.1	tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine
YP_002399297.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14730969, 20187555, 20316830, 20580749, 21438845, 90046892, 92409600, 9801309, 2001994, 2197596, 9846876; Product type e : enzyme
YP_002399298.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14594836, 10493123, 9298646, 9868784; Product type f : factor
YP_002399299.1	Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues
YP_002399300.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88029453, 90323001, 3311747; Product type t : transporter
YP_002399301.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87222180, 87260820; Product type e : enzyme
YP_002399302.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399303.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002399304.1	Evidence 7 : Gene remnant; Product type pe : putative enzyme
YP_002399305.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002399306.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399307.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399308.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399309.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002399310.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002399311.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399312.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399313.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399314.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399315.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399316.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399317.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399318.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399319.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399320.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10498708
YP_002399321.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002399322.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399323.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002399324.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399325.1	catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism
YP_002399326.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type ps : putative structure
YP_002399327.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002399328.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7868611, 10464203; Product type pe : putative enzyme
YP_002399329.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399330.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8626329
YP_002399331.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399332.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3053170; Product type pe : putative enzyme
YP_002399333.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399334.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399335.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399336.1	Evidence 6 : Doubtful CDS
YP_002399337.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399338.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399339.1	catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
YP_002399340.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399341.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399342.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399343.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399344.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399345.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399346.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399347.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399348.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399349.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399350.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399351.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399352.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399353.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7519596; Product type pf : putative factor
YP_002399354.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11053371; Product type pf : putative factor
YP_002399355.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002399356.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399357.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14594833; Product type h : extrachromosomal origin
YP_002399358.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14594833; Product type h : extrachromosomal origin
YP_002399359.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399360.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399361.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399362.1	Evidence 6 : Doubtful CDS
YP_002399363.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399364.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399365.1	Rac prophage
YP_002399366.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002399367.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002399368.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002399369.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12011003; Product type s : structure
YP_002399370.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002399371.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002399372.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12011003; Product type pm : putative membrane component
YP_002399373.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002399374.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12011003; Product type pm : putative membrane component
YP_002399375.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 3029698; Product type m : membrane component
YP_002399376.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 9603870; Product type m : membrane component
YP_002399377.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 9603870; Product type m : membrane component
YP_002399378.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 9603870; Product type m : membrane component
YP_002399379.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 3065610; Product type e : enzyme
YP_002399380.1	Evidence 6 : Doubtful CDS
YP_002399381.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399382.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399383.1	Evidence 5 : No homology to any previously reported sequences
YP_002399384.1	Evidence 5 : No homology to any previously reported sequences
YP_002399385.1	Evidence 5 : No homology to any previously reported sequences
YP_002399386.1	Evidence 5 : No homology to any previously reported sequences
YP_002399387.1	Evidence 5 : No homology to any previously reported sequences
YP_002399388.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399389.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399390.1	Evidence 5 : No homology to any previously reported sequences
YP_002399391.1	Evidence 5 : No homology to any previously reported sequences
YP_002399392.1	Evidence 5 : No homology to any previously reported sequences
YP_002399393.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399394.1	Evidence 5 : No homology to any previously reported sequences
YP_002399395.1	Evidence 5 : No homology to any previously reported sequences
YP_002399396.1	Evidence 5 : No homology to any previously reported sequences
YP_002399397.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002399398.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002399399.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399400.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399401.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399402.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399403.1	RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
YP_002399404.1	Evidence 5 : No homology to any previously reported sequences
YP_002399405.1	Evidence 1b : Function experimentally demonstrated in the studied species; Product type m : membrane component
YP_002399406.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8451198, 8276869; Product type pe : putative enzyme
YP_002399407.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8451198, 8276869; Product type pe : putative enzyme
YP_002399408.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399409.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399410.1	iron-responsive element (ireA); ireA gene is located on pathogenicity island I (PAI I); outer membrane protein
YP_002399411.1	Evidence 5 : No homology to any previously reported sequences
YP_002399412.1	Evidence 5 : No homology to any previously reported sequences
YP_002399413.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399414.1	Evidence 5 : No homology to any previously reported sequences
YP_002399415.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399416.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399417.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399418.1	Evidence 6 : Doubtful CDS
YP_002399419.1	IrgA-homologue adhesin (Iha); TonB-dependent; acts as a specific receptor of enterobactin; fur-regulated; urovirulence factor
YP_002399420.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399421.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399422.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002399423.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399424.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399425.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399426.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399427.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399428.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399429.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399430.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399431.1	Evidence 5 : No homology to any previously reported sequences
YP_002399432.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399433.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002399434.1	Evidence 5 : No homology to any previously reported sequences
YP_002399435.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme
YP_002399436.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399437.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399438.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399439.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399440.1	Evidence 7 : Gene remnant
YP_002399441.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399442.1	Evidence 6 : Doubtful CDS
YP_002399443.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399444.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type cp : cell process
YP_002399445.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399446.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399447.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399448.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 8253690; Product type e : enzyme
YP_002399449.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8253690; Product type t : transporter
YP_002399450.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8021185; Product type t : transporter
YP_002399451.1	CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS
YP_002399452.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8397187, 8326861; Product type t : transporter
YP_002399453.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8397187, 8326861; Product type t : transporter
YP_002399454.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399455.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399456.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1856162, 8051103, 2082146; Product type t : transporter
YP_002399457.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1856162, 7715449; Product type t : transporter
YP_002399458.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399459.1	similar to general secretory pathway protein L
YP_002399460.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399461.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399462.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399463.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399464.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399465.1	Evidence 2b : Function of strongly homologous gene; Product type t : transporter
YP_002399466.1	Evidence 2b : Function of strongly homologous gene; Product type t : transporter
YP_002399467.1	Evidence 2b : Function of strongly homologous gene; Product type t : transporter
YP_002399468.1	part of the general (type II) secretion pathway (GSP), a signal sequence-dependent process responsible for protein export; involved in trans-location of exoproteins from the cytoplasm to the periplasm
YP_002399469.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399470.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98175453; Product type e : enzyme
YP_002399471.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 1644747; Product type lp : lipoprotein
YP_002399472.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11785976, 21178909, 11283302; Product type t : transporter
YP_002399473.1	catalyzes the formation of malate from glyoxylate and acetyl-CoA
YP_002399474.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399475.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96178972, 8606183; Product type e : enzyme
YP_002399476.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96178972, 8606183; Product type e : enzyme
YP_002399477.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96178972, 9880556, 8606183; Product type r : regulator
YP_002399478.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399479.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399480.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399481.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399482.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399483.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399484.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399485.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399486.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002399487.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399488.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399489.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399490.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21336523, 21382172, 7775463; Product type t : transporter
YP_002399491.1	catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction
YP_002399492.1	YghU; B2989; one of eight putative glutathione transferase proteins from E. coli
YP_002399493.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92215587, 94292472, 8021226; Product type pf : putative factor
YP_002399494.1	plays a role in hydrogenase nickel cofactor insertion
YP_002399495.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94292472, 8021226; Product type f : factor
YP_002399496.1	protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC)
YP_002399497.1	involved in hydrogen uptake
YP_002399498.1	HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits
YP_002399499.1	Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2
YP_002399500.1	involved in hydrogen uptake
YP_002399501.1	Evidence 6 : Doubtful CDS
YP_002399502.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399503.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399504.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12583903; Product type e : enzyme
YP_002399505.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399506.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399507.1	membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell
YP_002399508.1	membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell
YP_002399509.1	Evidence 6 : Doubtful CDS
YP_002399510.1	catalyzes the formation of L-homocysteine from cystathionine
YP_002399511.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399512.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399513.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15327949; Product type e : enzyme
YP_002399514.1	methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate
YP_002399515.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399516.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002399517.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002399518.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002399519.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399520.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399521.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399522.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399523.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002399524.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399525.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399526.1	Evidence 2b : Function of strongly homologous gene; Product type t : transporter
YP_002399527.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88314889, 1557036, 9298646; Product type r : regulator
YP_002399528.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92212294, 1557036; Product type e : enzyme
YP_002399529.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399530.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_002399531.1	YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system
YP_002399532.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399533.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9298646
YP_002399534.1	response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes
YP_002399535.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21927389; Product type r : regulator
YP_002399536.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399537.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399538.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96004656, 96217538; Product type c : carrier
YP_002399539.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10493123, 9298646, 9600841, 9868784; Product type e : enzyme
YP_002399540.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399541.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399542.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399543.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399544.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : putative receptor
YP_002399545.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
YP_002399546.1	Displays esterase activity toward palmitoyl-CoA and pNP-butyrate
YP_002399547.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96411758; Product type e : enzyme
YP_002399548.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399549.1	ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose
YP_002399550.1	trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell
YP_002399551.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399552.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399553.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8887346, 11534764; Product type e : enzyme
YP_002399554.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8887346, 10600454; Product type e : enzyme
YP_002399555.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10600454; Product type pe : putative enzyme
YP_002399556.1	seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine
YP_002399557.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11790762, 1314093; Product type t : transporter
YP_002399558.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399559.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002399560.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002399561.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002399562.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002399563.1	DHBP synthase; functions during riboflavin biosynthesis
YP_002399564.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399565.1	Involved in glycogen synthesis. May be involved in glycogen priming
YP_002399566.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399567.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399568.1	catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose
YP_002399569.1	catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme
YP_002399570.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8412694; Product type pe : putative enzyme
YP_002399571.1	Evidence 6 : Doubtful CDS
YP_002399572.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11274153; Product type pr : putative regulator
YP_002399573.1	catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases
YP_002399574.1	BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell
YP_002399575.1	catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin
YP_002399576.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX
YP_002399577.1	activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol
YP_002399578.1	Involved in the tartrate degradation pathway
YP_002399579.1	Involved in the tartrate degradation pathway
YP_002399580.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399581.1	in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity
YP_002399582.1	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
YP_002399583.1	synthesizes RNA primers at the replication forks
YP_002399584.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria
YP_002399585.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20412902, 99453007, 6269063, 7567469, 8878487, 9489705; Product type e : enzyme
YP_002399586.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002399587.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399588.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20015410, 9380671, 9643537, 9190831; Product type r : regulator
YP_002399589.1	catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate
YP_002399590.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 11101501
YP_002399591.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89128452, 2515108, 3939708; Product type r : regulator
YP_002399592.1	in Escherichia coli this is the second beta-galactosidase system
YP_002399593.1	in Escherichia coli this is the second beta-galactosidase system
YP_002399594.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399595.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399596.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15213393; Product type pe : putative enzyme
YP_002399597.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12840019, 89380266; Product type e : enzyme
YP_002399598.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399599.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399600.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399601.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002399602.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399603.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12107143, 2108134; Product type pm : putative membrane component
YP_002399604.1	involved in the import of serine and threonine coupled with the import of sodium
YP_002399605.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399606.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4570160, 83114543, 3038546; Product type e : enzyme
YP_002399607.1	catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism
YP_002399608.1	regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.
YP_002399609.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399610.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11274153
YP_002399611.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399612.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399613.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399614.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399615.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399616.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 8478329; Product type e : enzyme
YP_002399617.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399618.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399619.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399620.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399621.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399622.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399623.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98143432, 9484901; Product type e : enzyme
YP_002399624.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 12777779, 9484901; Product type e : enzyme
YP_002399625.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98143432, 9484901; Product type e : enzyme
YP_002399626.1	catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism
YP_002399627.1	involved in the import of threonine and serine in combination with the import of a proton
YP_002399628.1	catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic
YP_002399629.1	regulates the tdcABCDEFG operon which is involved in amino acid degradation
YP_002399630.1	participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon
YP_002399631.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20225875, 69151449, 9772162; Product type e : enzyme
YP_002399632.1	catalyzes the reduction of tartronate semialdehyde to glycerate
YP_002399633.1	cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate
YP_002399634.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20225875, 66096392, 81027430, 9772162, 10762278, 2407727; Product type e : enzyme
YP_002399635.1	SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation
YP_002399636.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399637.1	transcriptional repressor for the agaZVWA and agaSYBCDI operons
YP_002399638.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11976750, 20392444, 10931310, 8932697; Product type e : enzyme
YP_002399639.1	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport
YP_002399640.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399641.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399642.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399643.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002399644.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689210, 9697096, 14731281, 8932697; Product type e : enzyme
YP_002399645.1	catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
YP_002399646.1	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport
YP_002399647.1	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport
YP_002399648.1	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport
YP_002399649.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10931310; Product type e : enzyme
YP_002399650.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399651.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399652.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399653.1	Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein
YP_002399654.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11274153
YP_002399655.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399656.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399657.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399658.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399659.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399660.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399661.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002399662.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 10206698; Product type e : enzyme
YP_002399663.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 10206698; Product type e : enzyme
YP_002399664.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399665.1	tryptophan transporter of high affinity
YP_002399666.1	participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division
YP_002399667.1	lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing
YP_002399668.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87083499, 91198209, 99234021, 99340204, 2432069, 3005122, 6382163, 9008164, 9298646; Product type e : enzyme
YP_002399669.1	primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence
YP_002399670.1	catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs
YP_002399671.1	associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock
YP_002399672.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YP_002399673.1	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
YP_002399674.1	in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins
YP_002399675.1	catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis
YP_002399676.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399677.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20194819, 21125563, 9020118, 94074540, 9564033, 9644254, 9829959, 99298179, 7556084, 8034620, 8045257, 8244950, 8253068; Product type t : transporter
YP_002399678.1	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YP_002399679.1	catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate
YP_002399680.1	inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins
YP_002399681.1	Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit
YP_002399682.1	RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability
YP_002399683.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YP_002399684.1	penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains
YP_002399685.1	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication
YP_002399686.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399687.1	involved in the peptidyltransferase reaction during translation
YP_002399688.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91088242, 94146411, 10094780, 387076, 8312607; Product type s : structure
YP_002399689.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94311902, 97284515, 2670911, 8037730, 8312607; Product type e : enzyme
YP_002399690.1	activator of maltose metabolism genes
YP_002399691.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
YP_002399692.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399693.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399694.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 9658016; Product type t : transporter
YP_002399695.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 9658016; Product type t : transporter
YP_002399696.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 9658016; Product type t : transporter
YP_002399697.1	ATP-binding subunit of a putative ABC toluene efflux transporter
YP_002399698.1	YrbG; inner membrane protein involved in cell envelope integrity; putative sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers
YP_002399699.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12805358; Product type e : enzyme
YP_002399700.1	forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis
YP_002399701.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399702.1	LptA; periplasmic binding protein part of a putative ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system
YP_002399703.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7876255, 9298646, 17056748; Product type pt : putative transporter
YP_002399704.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen
YP_002399705.1	YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing
YP_002399706.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88212176, 90136533, 90274974, 95020584, 95181483, 7876255, 8025669, 8444818, 9636714; Product type t : transporter
YP_002399707.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399708.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10473571, 95181483, 7876255, 8025669; Product type t : transporter
YP_002399709.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 89083480
YP_002399710.1	glycosyltransferase; polymerizes glycan strands in the peptidoglycan
YP_002399711.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92246944, 98269038, 1575737, 9603997; Product type pe : putative enzyme
YP_002399712.1	sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA
YP_002399713.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399714.1	catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate
YP_002399715.1	glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate
YP_002399716.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399717.1	catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein
YP_002399718.1	Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate
YP_002399719.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96011396, 9864311, 7592358; Product type t : transporter
YP_002399720.1	catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid
YP_002399721.1	Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization
YP_002399722.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12445774, 94293773, 1721886, 3029697, 8022275; Product type f : factor
YP_002399723.1	transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation
YP_002399724.1	forms a direct contact with the tRNA during translation
YP_002399725.1	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
YP_002399726.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399727.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16079137; Product type pe : putative enzyme
YP_002399728.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8830688, 96165272, 8576051, 8576052, 9740056; Product type e : enzyme
YP_002399729.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15137941, 15225661, 21352996, 96165272, 99431977, 3322223, 8576051; Product type e : enzyme
YP_002399730.1	oxidizes malate to oxaloacetate
YP_002399731.1	regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes
YP_002399732.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399733.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399734.1	with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate
YP_002399735.1	with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate
YP_002399736.1	membrane protein AaeX; the gene is a member of the aaeXAB operon
YP_002399737.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15489430; Product type r : regulator
YP_002399738.1	responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA
YP_002399739.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10960106; Product type pm : putative membrane component
YP_002399740.1	involved in the processing of the 5'end of 16S rRNA
YP_002399741.1	Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell
YP_002399742.1	part of cell wall structural complex MreBCD; transmembrane component
YP_002399743.1	Evidence 6 : Doubtful CDS
YP_002399744.1	in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall
YP_002399745.1	functions in MreBCD complex in some organisms
YP_002399746.1	Evidence 6 : Doubtful CDS
YP_002399747.1	regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules
YP_002399748.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399749.1	Evidence 6 : Doubtful CDS
YP_002399750.1	composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism
YP_002399751.1	an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
YP_002399752.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399753.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399754.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399755.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399756.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399757.1	catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
YP_002399758.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399759.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399760.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399761.1	mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase
YP_002399762.1	methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype
YP_002399763.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22095566, 1459953, 1547773, 2835774, 2837762, 8226664; Product type e : enzyme
YP_002399764.1	Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription
YP_002399765.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15028690, 9073062; Product type e : enzyme
YP_002399766.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399767.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8203018, 11257026, 8407802, 1720861; Product type r : regulator
YP_002399768.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94012493, 1720861; Product type lp : lipoprotein
YP_002399769.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94262163, 99449638, 1720861, 8407802; Product type t : transporter
YP_002399770.1	Evidence 6 : Doubtful CDS
YP_002399771.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002399772.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399773.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399774.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 8898392; Product type t : transporter
YP_002399775.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 8898392; Product type t : transporter
YP_002399776.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 8898392; Product type t : transporter
YP_002399777.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 8809753, 8898392; Product type t : transporter
YP_002399778.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399779.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399780.1	AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate
YP_002399781.1	RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA
YP_002399782.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399783.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8432722
YP_002399784.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8112305, 8432722
YP_002399785.1	cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+)
YP_002399786.1	modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth
YP_002399787.1	catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase
YP_002399788.1	involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain
YP_002399789.1	forms homopentamer; channel that opens in response to pressure or hypoosmotic shock
YP_002399790.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399791.1	mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators
YP_002399792.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399793.1	is a component of the macrolide binding site in the peptidyl transferase center
YP_002399794.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
YP_002399795.1	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination
YP_002399796.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
YP_002399797.1	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA
YP_002399798.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
YP_002399799.1	late assembly protein
YP_002399800.1	L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7
YP_002399801.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
YP_002399802.1	binds 5S rRNA along with protein L5 and L25
YP_002399803.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
YP_002399804.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YP_002399805.1	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif
YP_002399806.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
YP_002399807.1	assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel
YP_002399808.1	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase
YP_002399809.1	primary binding protein; helps mediate assembly; involved in translation fidelity
YP_002399810.1	one of the stabilizing components for the large ribosomal subunit
YP_002399811.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
YP_002399812.1	forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation
YP_002399813.1	binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center
YP_002399814.1	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YP_002399815.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
YP_002399816.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
YP_002399817.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
YP_002399818.1	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
YP_002399819.1	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex
YP_002399820.1	calcium-binding protein that may be required for the initiation of chromosome replication
YP_002399821.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 96256608; Product type t : transporter
YP_002399822.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 96256608; Product type t : transporter
YP_002399823.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 96256608; Product type t : transporter
YP_002399824.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 96256608, 7896718; Product type t : transporter
YP_002399825.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 95204361, 96256608; Product type t : transporter
YP_002399826.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96256608; Product type pt : putative transporter
YP_002399827.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 96256608, 1588814; Product type t : transporter
YP_002399828.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96256608; Product type pt : putative transporter
YP_002399829.1	Evidence 6 : Doubtful CDS
YP_002399830.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10760150, 10419961, 2661540; Product type e : enzyme
YP_002399831.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_002399832.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
YP_002399833.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
YP_002399834.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
YP_002399835.1	in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs
YP_002399836.1	in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs
YP_002399837.1	in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs
YP_002399838.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399839.1	rotamase
YP_002399840.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399841.1	rotamase
YP_002399842.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399843.1	involved in potassium efflux
YP_002399844.1	required for KefB activity
YP_002399845.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399846.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9889164; Product type pe : putative enzyme
YP_002399847.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399848.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 2559876; Product type e : enzyme
YP_002399849.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399850.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399851.1	complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons
YP_002399852.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399853.1	DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate
YP_002399854.1	aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity
YP_002399855.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92021789, 94095125, 2007139, 2403545, 2546924, 7549107; Product type cp : cell process
YP_002399856.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399857.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90272647, 91175755, 1606970, 2001362, 2007139, 2190212, 2403545, 2546924, 8130188, 8180197; Product type e : enzyme
YP_002399858.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20509826; Product type pt : putative transporter
YP_002399859.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93062014, 2200672, 2445993, 2543955; Product type e : enzyme
YP_002399860.1	involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations
YP_002399861.1	member of the FNT family of formate and nitrite transporters
YP_002399862.1	multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin
YP_002399863.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399864.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399865.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399866.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399867.1	phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE)
YP_002399868.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399869.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399870.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399871.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399872.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002399873.1	catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate
YP_002399874.1	catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate
YP_002399875.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90136529, 92262475, 92272672, 2549371, 6300769, 7603433, 8341592; Product type e : enzyme
YP_002399876.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399877.1	catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis
YP_002399878.1	type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis
YP_002399879.1	outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa
YP_002399880.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399881.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399882.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002399883.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
YP_002399884.1	bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits
YP_002399885.1	ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose
YP_002399886.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11553591; Product type r : regulator
YP_002399887.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399888.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9867837, 10675343, 10675344; Product type f : factor
YP_002399889.1	becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers
YP_002399890.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 20223645; Product type pm : putative membrane component
YP_002399891.1	Evidence 6 : Doubtful CDS
YP_002399892.1	PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP
YP_002399893.1	membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR
YP_002399894.1	part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation
YP_002399895.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YP_002399896.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 8755871; Product type f : factor
YP_002399897.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94012482, 8407793; Product type t : transporter
YP_002399898.1	cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake
YP_002399899.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002399900.1	Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis
YP_002399901.1	involved in high-affinity gluconate transport
YP_002399902.1	cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source
YP_002399903.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 172599, 4574689, 4582156, 93139975, 97141270, 98019089, 2845225, 3040894, 7984428, 9045817; Product type t : transporter
YP_002399904.1	amylomaltase; acts to release glucose from maltodextrins
YP_002399905.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89033892, 10220320, 10469642, 2845225, 3037809, 3155826, 6283313, 6339728, 6986282, 9009262; Product type e : enzyme
YP_002399906.1	Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides
YP_002399907.1	catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester
YP_002399908.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9738023
YP_002399909.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9738023, 3045764, 7920643, 7984428; Product type r : regulator
YP_002399910.1	represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism
YP_002399911.1	protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity
YP_002399912.1	belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine
YP_002399913.1	in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane
YP_002399914.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399915.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399916.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399917.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15213132; Product type ps : putative structure
YP_002399918.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002399919.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002399920.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15213132; Product type pf : putative factor
YP_002399921.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15213132; Product type ps : putative structure
YP_002399922.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : putative structure
YP_002399923.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002399924.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002399925.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15213132; Product type pf : putative factor
YP_002399926.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15213132; Product type pf : putative factor
YP_002399927.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002399928.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002399929.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88330897, 91104907, 91236706, 2645169, 2975249, 3047129, 3097003; Product type e : enzyme
YP_002399930.1	catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose
YP_002399931.1	catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate
YP_002399932.1	catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen
YP_002399933.1	catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain
YP_002399934.1	catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde
YP_002399935.1	YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP)
YP_002399936.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8655507, 9119199, 9135111, 97141270; Product type t : transporter
YP_002399937.1	thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate
YP_002399938.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 172599, 9135111, 93139975, 9537375, 8655507; Product type r : regulator
YP_002399939.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399940.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10493123; Product type pe : putative enzyme
YP_002399941.1	YhhY; regulated by the fur regulator; unknown function
YP_002399942.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399943.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399944.1	periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides
YP_002399945.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399946.1	hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate
YP_002399947.1	part of the UgpABCE glycerol-3-phosphate uptake system
YP_002399948.1	with UgpABC is involved in uptake of glycerol-3-phosphate
YP_002399949.1	with UgpEC is involved in the uptake of glycerol-3-phosphate
YP_002399950.1	with UgpACE is involved in the uptake of glycerol-3-phosphate
YP_002399951.1	with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine
YP_002399952.1	Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine
YP_002399953.1	Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine
YP_002399954.1	LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter
YP_002399955.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14702302, 90307651, 2195019, 2649683, 3891753, 4077929, 9298646, 9298646; Product type t : transporter
YP_002399956.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399957.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14702302, 90307651, 2195019, 2649682, 328304, 3891753, 4077929, 9298646, 10972807; Product type t : transporter
YP_002399958.1	binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters
YP_002399959.1	putative ABC transporter, membrane protein
YP_002399960.1	putative ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions
YP_002399961.1	signal recognition protein receptor; functions in the targeting and insertion of membrane proteins
YP_002399962.1	catalyzes the methylation of 16S rRNA at position G966
YP_002399963.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399964.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002399965.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399966.1	P-type ATPase involved in the export of lead, cadmium, zinc and mercury
YP_002399967.1	TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs
YP_002399968.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399969.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12558182, 8752353; Product type t : transporter
YP_002399970.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399971.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399972.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20092861, 10625633, 8939709; Product type e : enzyme
YP_002399973.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12960164, 7934931, 92077434, 7867647; Product type t : transporter
YP_002399974.1	with NikACDE is involved in nickel transport into the cell
YP_002399975.1	with NikABDE is involved in nickel transport into the cell
YP_002399976.1	with NikABCE is involved in nickel transport into the cell
YP_002399977.1	with NikABCD is involved with nickel transport into the cell
YP_002399978.1	Inhibits transcription at high concentrations of nickel
YP_002399979.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399980.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20074572; Product type e : enzyme
YP_002399981.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002399982.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002399983.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002399984.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87014120; Product type t : transporter
YP_002399985.1	ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress
YP_002399986.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12732303, 93086426, 93308072, 94203056, 10499297, 10652104, 10931298, 11157932, 1453957, 8506346, 8932299, 9298646, 9405142; Product type f : factor
YP_002399987.1	member of the POT family of peptide transporters; probable proton-dependent peptide transporter function
YP_002399988.1	predicted SAM-dependent methyltransferase
YP_002399989.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92394891, 1325967, 8366062; Product type e : enzyme
YP_002399990.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11591672; Product type pe : putative enzyme
YP_002399991.1	catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense
YP_002399992.1	Evidence 6 : Doubtful CDS
YP_002399993.1	Evidence 6 : Doubtful CDS
YP_002399994.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95355341, 7721697; Product type e : enzyme
YP_002399995.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293775, 8022277; Product type lp : lipoprotein
YP_002399996.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8022277; Product type pr : putative regulator
YP_002399997.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16275907; Product type e : enzyme
YP_002399998.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7768795, 9393841, 9680204; Product type pt : putative transporter
YP_002399999.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_002400000.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400001.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400002.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400003.1	with HmuTU is involved in the transport of hemin
YP_002400004.1	inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli
YP_002400005.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94064579, 8885264, 12071744, 8244952, 8455549, 9298646, 9868784; Product type pf : putative factor
YP_002400006.1	inactive form
YP_002400007.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94064579, 8244952, 8455549; Product type pm : putative membrane component
YP_002400008.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12399493, 12940989, 14702398; Product type r : regulator
YP_002400009.1	with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds
YP_002400010.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803; Product type t : transporter
YP_002400011.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12446650; Product type r : regulator
YP_002400012.1	regulates genes in response to acid and/or during stationary phase
YP_002400013.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92155241, 92394884, 99406302, 1522060, 1740158, 7764225, 9298646; Product type e : enzyme
YP_002400014.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8163487, 14563563; Product type e : enzyme
YP_002400015.1	cytoplasmic; catalyzes the hydrolysis of trehalose to glucose
YP_002400016.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400017.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400018.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400019.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400020.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002400021.1	in Escherichia coli this protein is involved in flagellar function
YP_002400022.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4359651, 13813474; Product type e : enzyme
YP_002400023.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pe : putative enzyme
YP_002400024.1	involved in the transport of C4-dicarboxylates across the membrane
YP_002400025.1	HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a putative phosphodiesterase protein from E. coli
YP_002400026.1	cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA
YP_002400027.1	catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans
YP_002400028.1	binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP)
YP_002400029.1	polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis
YP_002400030.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9054507; Product type pe : putative enzyme
YP_002400031.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400032.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11929533, 11260463; Product type pe : putative enzyme
YP_002400033.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400034.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11929533, 11260463; Product type pe : putative enzyme
YP_002400035.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400036.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 15901718; Product type t : transporter
YP_002400037.1	Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides
YP_002400038.1	DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF
YP_002400039.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7536291; Product type t : transporter
YP_002400040.1	transports peptides consisting of two or three amino acids
YP_002400041.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91100289, 92065799, 1702779, 1956284, 7536291, 8527431, 8563629, 9298646, 9600841, 9740056, 10972807; Product type t : transporter
YP_002400042.1	catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide
YP_002400043.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14977923; Product type pm : putative membrane component
YP_002400044.1	Evidence 7 : Gene remnant; Product type s : structure
YP_002400045.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002400046.1	Evidence 7 : Gene remnant; Product type s : structure
YP_002400047.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14977923; Product type m : membrane component
YP_002400048.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14977923; Product type m : membrane component
YP_002400049.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14977923; Product type m : membrane component
YP_002400050.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400051.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400052.1	constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine
YP_002400053.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11237876; Product type pe : putative enzyme
YP_002400054.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82119950, 90202748, 2180922, 374979; Product type e : enzyme
YP_002400055.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002400056.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15801772, 11237876, 99030322, 99357626, 9298646, 9811658; Product type e : enzyme
YP_002400057.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400058.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400059.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20345064, 90115858, 94293754, 94293756, 99177178, 10696873, 1597410, 1961761, 2404279, 7515185, 8197194, 9405743, 9439003, 9692981; Product type f : factor
YP_002400060.1	glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
YP_002400061.1	glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
YP_002400062.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400063.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400064.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6320721; Product type pm : putative membrane component
YP_002400065.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6330500, 92366447, 95050816, 6320721; Product type e : enzyme
YP_002400066.1	catalyzes the interconversion of D-xylose to D-xylulose
YP_002400067.1	periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity
YP_002400068.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94316500; Product type t : transporter
YP_002400069.1	Evidence 6 : Doubtful CDS
YP_002400070.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6330500, 94316500; Product type r : regulator
YP_002400071.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1544897
YP_002400072.1	periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds
YP_002400073.1	transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis
YP_002400074.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002400075.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 20372646, 9826648; Product type r : regulator
YP_002400076.1	NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate
YP_002400077.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 21617392
YP_002400078.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400079.1	membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO
YP_002400080.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14668138, 21617392; Product type t : transporter
YP_002400081.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14668138, 21617392; Product type t : transporter
YP_002400082.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21617392, 95050816, 7961955; Product type e : enzyme
YP_002400083.1	catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate
YP_002400084.1	L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate
YP_002400085.1	catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
YP_002400086.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95286498, 7768815; Product type e : enzyme
YP_002400087.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400088.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2935393; Product type e : enzyme
YP_002400089.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264431, 91317715, 9315303, 94148228, 2140572, 2531290; Product type f : factor
YP_002400090.1	catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis
YP_002400091.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8387990; Product type pe : putative enzyme
YP_002400092.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400093.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400094.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92052139, 92283796, 94131964, 1946374, 3135464, 3142516, 6309813, 9551558; Product type t : transporter
YP_002400095.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90254197, 1964486, 3135464, 6384188, 8300537, 13295236; Product type e : enzyme
YP_002400096.1	Acts as a repressor of the mtlAD operon
YP_002400097.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400098.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400099.1	Evidence 6 : Doubtful CDS
YP_002400100.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400101.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002400102.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94012541, 11283302, 11785976, 8407843; Product type t : transporter
YP_002400103.1	represses the lctPRD operon
YP_002400104.1	flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration
YP_002400105.1	member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates
YP_002400106.1	catalyzes the O-acetylation of serine
YP_002400107.1	catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate
YP_002400108.1	molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA
YP_002400109.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94316500, 95024051, 99175138, 11031118, 7937896, 8636094, 9973569; Product type c : carrier
YP_002400110.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400111.1	catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
YP_002400112.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12113939, 21972773; Product type cp : cell process
YP_002400113.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400114.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15659689, 2647748; Product type pe : putative enzyme
YP_002400115.1	converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism
YP_002400116.1	catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine
YP_002400117.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400118.1	catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose
YP_002400119.1	catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core
YP_002400120.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20507564, 92250420, 93239678, 9446588, 1624462, 8478319; Product type e : enzyme
YP_002400121.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1657881; Product type e : enzyme
YP_002400122.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002400123.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92210496, 92250420, 92325066, 99251135, 1624461; Product type e : enzyme
YP_002400124.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1624462, 8041620, 9278503, 92250420, 92325067, 9756860; Product type e : enzyme
YP_002400125.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92210496, 92250420, 92325066, 9765561, 1624461; Product type e : enzyme
YP_002400126.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21101922, 92121133, 92210496, 9756860, 1732225; Product type e : enzyme
YP_002400127.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92121133, 92210496, 92250420, 1447141, 1732225, 7988890; Product type e : enzyme
YP_002400128.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9756860, 1447141, 1732225; Product type e : enzyme
YP_002400129.1	catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A
YP_002400130.1	Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA
YP_002400131.1	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases
YP_002400132.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif
YP_002400133.1	required for 70S ribosome assembly
YP_002400134.1	Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase
YP_002400135.1	catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine
YP_002400136.1	catalyzes the formation of dUMP from dUTP
YP_002400137.1	FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly
YP_002400138.1	involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_002400139.1	RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs
YP_002400140.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400141.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400142.1	this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+
YP_002400143.1	Essential for recycling GMP and indirectly, cGMP
YP_002400144.1	promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
YP_002400145.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12224635, 89255395, 93266525, 94068533, 2005134, 2549050; Product type e : enzyme
YP_002400146.1	specifically modifies tRNA at position G18
YP_002400147.1	catalyzes branch migration in Holliday junction intermediates
YP_002400148.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91203811, 93106943, 1544582, 2017136, 2254324; Product type t : transporter
YP_002400149.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400150.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400151.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400152.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400153.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400154.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400155.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400156.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400157.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400158.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400159.1	catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides
YP_002400160.1	may be involved in the transport of galactosides-pentoses-hexuronides
YP_002400161.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400162.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400163.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400164.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88298691, 89359178, 9914480, 3003106; Product type lp : lipoprotein
YP_002400165.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400166.1	experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS
YP_002400167.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400168.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400169.1	catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type
YP_002400170.1	cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate
YP_002400171.1	membrane protein regulates uhpT expression
YP_002400172.1	Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph
YP_002400173.1	response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter
YP_002400174.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400175.1	with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit
YP_002400176.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2989782, 85242083, 92380929, 2989781; Product type e : enzyme
YP_002400177.1	Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide
YP_002400178.1	multidrug efflux protein involved in adaptation to low energy shock
YP_002400179.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400180.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400181.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400182.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400183.1	uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function
YP_002400184.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400185.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1356969; Product type pt : putative transporter
YP_002400186.1	16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent
YP_002400187.1	with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress
YP_002400188.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400189.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400190.1	FAD/NAD(P)-binding domain
YP_002400191.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 79020349; Product type t : transporter
YP_002400192.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 79020349; Product type e : enzyme
YP_002400193.1	catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism
YP_002400194.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 79020349; Product type e : enzyme
YP_002400195.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 79020349; Product type pr : putative regulator
YP_002400196.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002400197.1	YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins
YP_002400198.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400199.1	negatively supercoils closed circular double-stranded DNA
YP_002400200.1	Required for DNA replication; binds preferentially to single-stranded, linear DNA
YP_002400201.1	binds the polymerase to DNA and acts as a sliding clamp
YP_002400202.1	binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.
YP_002400203.1	in Escherichia coli transcription of this gene is enhanced by polyamines
YP_002400204.1	protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates
YP_002400205.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400206.1	functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria
YP_002400207.1	in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE
YP_002400208.1	Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide
YP_002400209.1	tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan
YP_002400210.1	tryptophan transporter of low affinity
YP_002400211.1	Confers resistance to chloramphenicol
YP_002400212.1	Involved in anaerobic NO protection
YP_002400213.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400214.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14766567; Product type e : enzyme
YP_002400215.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400216.1	YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily
YP_002400217.1	might be involved in hypersensitivity to nitrofurzone
YP_002400218.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400219.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400220.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10027967; Product type t : transporter
YP_002400221.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87222180, 88297127, 92334140, 3034860, 3309161; Product type e : enzyme
YP_002400222.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
YP_002400223.1	positive regulator of the beta-glucoside operon; transcriptional antiterminator
YP_002400224.1	regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon
YP_002400225.1	ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation
YP_002400226.1	Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions
YP_002400227.1	part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions
YP_002400228.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90133909, 2215649, 6321434, 6365894, 9228942, 9298646, 9671506; Product type t : transporter
YP_002400229.1	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
YP_002400230.1	forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis
YP_002400231.1	part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane
YP_002400232.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
YP_002400233.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit
YP_002400234.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
YP_002400235.1	Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex
YP_002400236.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.
YP_002400237.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0
YP_002400238.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0
YP_002400239.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation
YP_002400240.1	glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA
YP_002400241.1	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs
YP_002400242.1	An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
YP_002400243.1	transcriptional repressor of asnA which codes for aspartate-ammonia ligase
YP_002400244.1	catalyzes the formation of asparagine from aspartate and ammonia
YP_002400245.1	contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA
YP_002400246.1	interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase
YP_002400247.1	Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH
YP_002400248.1	cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source
YP_002400249.1	with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain
YP_002400250.1	functions to transport ribose at high affinity; forms a complex with RbsA2C2B
YP_002400251.1	periplasmic substrate-binding component of the ATP-dependent ribose transport system
YP_002400252.1	catalyzes the formation of D-ribose 5-phosphate from ribose
YP_002400253.1	DNA-binding transcriptional repressor of ribose metabolism
YP_002400254.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 20218988, 12107133; Product type t : transporter
YP_002400255.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400256.1	Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon
YP_002400257.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400258.1	among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function
YP_002400259.1	Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide
YP_002400260.1	catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit
YP_002400261.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92332418, 92380929, 1569580, 3550695, 3897211; Product type e : enzyme
YP_002400262.1	catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids
YP_002400263.1	catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis
YP_002400264.1	threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway
YP_002400265.1	participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate
YP_002400266.1	catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis
YP_002400267.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94215709, 7878732, 7925971, 8163020; Product type e : enzyme
YP_002400268.1	single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication
YP_002400269.1	catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation
YP_002400270.1	Evidence 6 : Doubtful CDS
YP_002400271.1	enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation
YP_002400272.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202710, 91154193, 92250497, 99175138, 10489448, 1094461, 10947986, 1561103, 2181145, 2193685, 3891733, 4616096, 4883076, 6098320, 6099324, 7812718, 8098620, 8253691; Product type c : carrier
YP_002400273.1	Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide
YP_002400274.1	An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes
YP_002400275.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92114763, 94245613, 94292435, 10629198, 11024259, 11700352, 11832520, 1722555, 1730666; Product type e : enzyme
YP_002400276.1	Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein
YP_002400277.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90212314, 90337949, 92112804, 94042873, 11106477, 7559340, 8170390, 8226648; Product type e : enzyme
YP_002400278.1	catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid
YP_002400279.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88086930, 90212314, 90337949, 92112804, 92174908, 94018634, 94042873, 7559340; Product type e : enzyme
YP_002400280.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94292435, 96032389; Product type e : enzyme
YP_002400281.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90212314, 90337949, 92112804, 8366065; Product type e : enzyme
YP_002400282.1	catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis
YP_002400283.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12621029, 20044778; Product type t : transporter
YP_002400284.1	catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis
YP_002400285.1	enterobacterial common antigen polymerase
YP_002400286.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88086874, 90337949, 92112804; Product type e : enzyme
YP_002400287.1	uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function
YP_002400288.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11222759, 2180918, 12419807, 14749327; Product type pr : putative regulator
YP_002400289.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16766528, 92358234, 15477040; Product type e : enzyme
YP_002400290.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 89041586; Product type pe : putative enzyme
YP_002400291.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 89098348, 92358234, 3054815, 3062586, 9298646; Product type pe : putative enzyme
YP_002400292.1	catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis
YP_002400293.1	transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis
YP_002400294.1	catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP
YP_002400295.1	defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly
YP_002400296.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002400297.1	involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate
YP_002400298.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400299.1	site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs
YP_002400300.1	YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function
YP_002400301.1	unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.
YP_002400302.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400303.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400304.1	responsible for the influx of magnesium ions
YP_002400305.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400306.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400307.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400308.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400309.1	catalyzes the hydrolysis of phosphatidylcholine
YP_002400310.1	functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway
YP_002400311.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99313167, 10386596, 3027506; Product type t : transporter
YP_002400312.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99313167, 10386596; Product type t : transporter
YP_002400313.1	lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates
YP_002400314.1	purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium
YP_002400315.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400316.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90384950, 96303520, 2205852, 2643109; Product type r : regulator
YP_002400317.1	catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine
YP_002400318.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400319.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 9200688; Product type t : transporter
YP_002400320.1	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase
YP_002400321.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400322.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400323.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400324.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400325.1	catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP
YP_002400326.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400327.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400328.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400329.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400330.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12676709; Product type pe : putative enzyme
YP_002400331.1	catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway
YP_002400332.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400333.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400334.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002400335.1	catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism
YP_002400336.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002400337.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400338.1	YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner
YP_002400339.1	Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone
YP_002400340.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400341.1	an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions
YP_002400342.1	TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes
YP_002400343.1	mediates the export of protein precursors bearing twin-arginine signal peptides
YP_002400344.1	with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane
YP_002400345.1	magnesium dependent; not involved in the Sec-independent protein export system
YP_002400346.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92011415, 92250420, 92261317, 1584020, 12007406; Product type r : regulator
YP_002400347.1	catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol
YP_002400348.1	NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin
YP_002400349.1	FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids
YP_002400350.1	includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids
YP_002400351.1	catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters
YP_002400352.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15103642; Product type pf : putative factor
YP_002400353.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91100357, 2243799, 7896723; Product type t : transporter
YP_002400354.1	catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX
YP_002400355.1	in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway
YP_002400356.1	in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis
YP_002400357.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400358.1	catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages
YP_002400359.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12498799, 93264419, 94016574, 94206930, 99298180, 10210188, 1429594, 1740115, 1934062, 8413591, 8494885, 8521518, 9194175, 9298646, 9300489, 9572841, 9600841, 9655827; Product type e : enzyme
YP_002400360.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400361.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400362.1	has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair
YP_002400363.1	binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential
YP_002400364.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400365.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_002400366.1	response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54
YP_002400367.1	sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation
YP_002400368.1	forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme
YP_002400369.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400370.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9642082, 7783627, 9298646, 9622352; Product type f : factor
YP_002400371.1	porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown
YP_002400372.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400373.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400374.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15294295; Product type e : enzyme
YP_002400375.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002400376.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400377.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400378.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400379.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400380.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400381.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400382.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400383.1	RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease
YP_002400384.1	hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine
YP_002400385.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400386.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400387.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400388.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400389.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400390.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400391.1	required for the formation of active formate dehydrogenase
YP_002400392.1	cytochrome b556(FDO) component; heme containing
YP_002400393.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91317715, 8522521, 9852007; Product type c : carrier
YP_002400394.1	Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme
YP_002400395.1	involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth
YP_002400396.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400397.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : putative membrane component
YP_002400398.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15060078; Product type e : enzyme
YP_002400399.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90128204, 93374854, 8396120; Product type e : enzyme
YP_002400400.1	catalyzes the formation of L-rhamnulose from L-rhamnose
YP_002400401.1	catalyzes the ATP-dependent phosphorylation of rhamnulose
YP_002400402.1	activates the expression of the rhaBAD operon and rhaT gene
YP_002400403.1	activates the expression of rhaRS in response to L-rhamnose
YP_002400404.1	transports L-rhamnose and L-lyxose into the cell
YP_002400405.1	SodA; manganese binding; only present under aerobic conditions; destroys free radicals
YP_002400406.1	transports degraded pectin products into the bacterial cell
YP_002400407.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400408.1	part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors
YP_002400409.1	response regulator in two-component regulatory system with CpxA; part of the envelope stress response system
YP_002400410.1	repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates
YP_002400411.1	member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers
YP_002400412.1	catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis
YP_002400413.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91161616, 2002055, 3158524, 8774726, 9298646; Product type t : transporter
YP_002400414.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86008270, 2995360, 3158524; Product type e : enzyme
YP_002400415.1	Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate
YP_002400416.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400417.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400418.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400419.1	with UspC and Usp E is involved in resistance to UV radiation
YP_002400420.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93194782, 94092163, 95050480, 95362685, 1400248, 2834327, 7961651, 8449868, 9149148; Product type e : enzyme
YP_002400421.1	type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese
YP_002400422.1	Converts glycerol and ADP to glycerol-3-phosphate and ADP
YP_002400423.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12629974, 12948772, 14646142, 15004242, 90094250, 92210584, 11039922, 11101882, 11226336, 11964478, 1372899, 2544860, 6998951; Product type t : transporter
YP_002400424.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400425.1	regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity
YP_002400426.1	catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate
YP_002400427.1	heat shock protein involved in degradation of misfolded proteins
YP_002400428.1	heat shock protein involved in degradation of misfolded proteins
YP_002400429.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9282742, 93285993, 8509333; Product type cp : cell process
YP_002400430.1	negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins
YP_002400431.1	binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity
YP_002400432.1	RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
YP_002400433.1	member of the NlpC/P60 superfamily of peptidases
YP_002400434.1	when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis
YP_002400435.1	catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine
YP_002400436.1	multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways
YP_002400437.1	Evidence 1b : Function experimentally demonstrated in the studied species; Product type m : membrane component
YP_002400438.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400439.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400440.1	MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor
YP_002400441.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90292022, 94209230, 3045098; Product type e : enzyme
YP_002400442.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400443.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400444.1	forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone
YP_002400445.1	similar to transaldolase from Escherichia coli; many organisms have multiple copies
YP_002400446.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 95291446, 7773398; Product type t : transporter
YP_002400447.1	FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site
YP_002400448.1	FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS
YP_002400449.1	involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein
YP_002400450.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95291446, 14673546, 7773398; Product type e : enzyme
YP_002400451.1	FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog
YP_002400452.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400453.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10456927; Product type pm : putative membrane component
YP_002400454.1	catalyzes the formation of oxaloacetate from phosphoenolpyruvate
YP_002400455.1	catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis
YP_002400456.1	catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate
YP_002400457.1	catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate
YP_002400458.1	catalyzes the formation of arginine from (N-L-arginino)succinate
YP_002400459.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 93341455, 94310441; Product type pe : putative enzyme
YP_002400460.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400461.1	Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA
YP_002400462.1	catalyzes the conversion of NADPH to NADH
YP_002400463.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7730270; Product type e : enzyme
YP_002400464.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400465.1	negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis
YP_002400466.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400467.1	catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs
YP_002400468.2	involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space
YP_002400469.1	converts L-glutamate to D-glutamate, a component of peptidoglycan
YP_002400470.1	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis
YP_002400471.1	catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon
YP_002400472.1	catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis
YP_002400473.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_002400474.1	forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force
YP_002400475.1	Modulates Rho-dependent transcription termination
YP_002400476.1	binds directly to 23S ribosomal RNA
YP_002400477.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
YP_002400478.1	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit
YP_002400479.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90094251, 92210551, 10094780, 3309338, 377281, 4573678, 773698, 8603708, 9298646, 9515737, 9600841, 9868784; Product type s : structure
YP_002400480.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme
YP_002400481.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter
YP_002400482.1	in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center
YP_002400483.1	functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate
YP_002400484.1	with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate
YP_002400485.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8432721, 94089392, 98298179, 10082377, 9632726; Product type e : enzyme
YP_002400486.1	catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate
YP_002400487.1	required for the synthesis of the hydromethylpyrimidine moiety of thiamine
YP_002400488.1	binds specifically to the major sigma factor sigma 70; active in stationary phase
YP_002400489.1	can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates
YP_002400490.1	catalyzes the formation of coproporphyrinogen from uroporphyrinogen III
YP_002400491.1	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures
YP_002400492.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400493.1	histone-like DNA-binding protein
YP_002400494.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400495.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98362023, 9694902; Product type pf : putative factor
YP_002400496.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21140164, 89327164, 92255260, 11243806, 2666400; Product type r : regulator
YP_002400497.1	DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein
YP_002400498.1	catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis
YP_002400499.1	involved in de novo purine biosynthesis
YP_002400500.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2412207
YP_002400501.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002400502.1	catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis
YP_002400503.1	Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle
YP_002400504.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91295197, 92112731, 92353108, 2836370, 3049537, 3060852, 3276689, 3290857, 3291954, 7826335; Product type e : enzyme
YP_002400505.1	catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol
YP_002400506.1	regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase
YP_002400507.1	one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity
YP_002400508.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400509.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400510.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400511.1	alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family
YP_002400512.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7652212; Product type e : enzyme
YP_002400513.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7700234; Product type t : transporter
YP_002400514.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7700234; Product type t : transporter
YP_002400515.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7700234, 12662934; Product type t : transporter
YP_002400516.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968; Product type t : transporter
YP_002400517.1	Converts D-sorbitol-dphosphate to D-fructose-6-phosphate
YP_002400518.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968; Product type r : regulator
YP_002400519.1	catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA
YP_002400520.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400521.1	catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive
YP_002400522.1	functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family
YP_002400523.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400524.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein
YP_002400525.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400526.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400527.1	Evidence 6 : Doubtful CDS
YP_002400528.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400529.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10986267; Product type pm : putative membrane component
YP_002400530.1	with MalKFE is involved in the transport of maltose into the cell
YP_002400531.1	with MalKGE is involved in maltose transport into the cell
YP_002400532.1	functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis
YP_002400533.1	with malEFG is involved in import of maltose/maltodextrin
YP_002400534.1	porin involved in the transport of maltose and maltodextrins
YP_002400535.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87141162, 2434655, 6086106; Product type pt : putative transporter
YP_002400536.1	catalyzes the formation of 4-hydroxybenzoate from chorismate
YP_002400537.1	catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway
YP_002400538.1	PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA
YP_002400539.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10220339, 6257698, 86278195, 88111690, 2984194, 6309817, 8071224; Product type e : enzyme
YP_002400540.1	Represses a number of genes involved in the response to DNA damage
YP_002400541.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87165788; Product type cp : cell process
YP_002400542.1	unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential
YP_002400543.1	Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB
YP_002400544.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22095566; Product type e : enzyme
YP_002400545.1	coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia
YP_002400546.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94089392, 7602590; Product type e : enzyme
YP_002400547.1	unwinds double stranded DNA
YP_002400548.1	converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer
YP_002400549.1	catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate
YP_002400550.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 10739245, 6376124; Product type e : enzyme
YP_002400551.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400552.1	Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme
YP_002400553.1	Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme
YP_002400554.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400555.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 3671068; Product type r : regulator
YP_002400556.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2134335; Product type prc : putative receptor
YP_002400557.1	Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity
YP_002400558.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11972052
YP_002400559.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400560.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YP_002400561.1	binds to single stranded DNA and PriA helcase facilitate replication restart
YP_002400562.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400563.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400564.1	regulates genes involved in response to oxidative stress
YP_002400565.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91210176, 91360349, 94139656, 9564045, 10207625, 12670967, 1653416, 1708380, 7673113, 8065907, 8306957, 8631739, 8969171, 9019397, 9092651, 9204707; Product type r : regulator
YP_002400566.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400567.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 21557160, 11479290; Product type pt : putative transporter
YP_002400568.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400569.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400570.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400571.1	member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake
YP_002400572.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14563880; Product type pm : putative membrane component
YP_002400573.1	Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA
YP_002400574.1	catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552
YP_002400575.1	part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia
YP_002400576.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94335626, 8057835; Product type c : carrier
YP_002400577.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91058381, 94335626, 8057835; Product type e : enzyme
YP_002400578.1	with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552
YP_002400579.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91058381, 94335626, 9593308, 8057835, 8842153; Product type f : factor
YP_002400580.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91058381, 94335626, 9593308, 8057835, 8842153; Product type f : factor
YP_002400581.1	carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system
YP_002400582.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400583.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400584.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400585.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400586.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400587.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400588.1	Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme
YP_002400589.1	part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family
YP_002400590.1	possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride
YP_002400591.1	with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride
YP_002400592.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1587481; Product type pe : putative enzyme
YP_002400593.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20026827, 9401019; Product type e : enzyme
YP_002400594.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20026827, 9401019; Product type e : enzyme
YP_002400595.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20026827, 9401019; Product type t : transporter
YP_002400596.1	with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains
YP_002400597.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20026827, 9401019, 10064713, 8576032; Product type t : transporter
YP_002400598.1	involved in rpiB and als operon repression
YP_002400599.1	catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity
YP_002400600.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400601.1	required for the use of phosphonates and phosphite as phosphorus sources
YP_002400602.1	PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role
YP_002400603.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12700258, 91100346, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme
YP_002400604.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91100346, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme
YP_002400605.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme
YP_002400606.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme
YP_002400607.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme
YP_002400608.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme
YP_002400609.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme
YP_002400610.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type e : enzyme
YP_002400611.1	may be involved in phosphonate uptake and biodegradation
YP_002400612.1	Evidence 2b : Function of strongly homologous gene; Product type t : transporter
YP_002400613.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type t : transporter
YP_002400614.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93122525, 93273711, 93328121, 9650256, 1840580, 2155230; Product type t : transporter
YP_002400615.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 93328121, 9650256, 2155230
YP_002400616.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9650256, 2155230; Product type pt : putative transporter
YP_002400617.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400618.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400619.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10049386, 12525168, 92165733, 93132799, 9871325, 99376621, 8421314; Product type t : transporter
YP_002400620.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94110256, 8282725; Product type r : regulator
YP_002400621.1	response regulator in two-component regulatory system with BasS
YP_002400622.1	with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division
YP_002400623.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12867448; Product type t : transporter
YP_002400624.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : c; Product type r : regulator
YP_002400625.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93186686, 2830169, 4204273, 8383109; Product type e : enzyme
YP_002400626.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90060832, 9108148, 1445207, 2684786, 2830169; Product type r : regulator
YP_002400627.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87174747, 88162811, 90248411, 2831880, 3031590, 6329200; Product type e : enzyme
YP_002400628.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400629.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86142617, 88193096, 89255123, 2656658; Product type e : enzyme
YP_002400630.1	functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters
YP_002400631.1	response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration
YP_002400632.1	C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration
YP_002400633.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400634.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400635.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400636.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400637.1	class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1
YP_002400638.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400639.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92105022, 92210511, 1370290, 1556085, 4204273; Product type e : enzyme
YP_002400640.1	antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein
YP_002400641.1	regulates the cadBA operon
YP_002400642.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400643.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400644.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400645.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14594833; Product type h : extrachromosomal origin
YP_002400646.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14594833; Product type h : extrachromosomal origin
YP_002400647.1	Evidence 6 : Doubtful CDS
YP_002400648.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002400649.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11053371; Product type pf : putative factor
YP_002400650.1	Evidence 6 : Doubtful CDS
YP_002400651.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400652.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400653.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400654.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400655.1	Evidence 7 : Gene remnant
YP_002400656.1	Evidence 7 : Gene remnant; Product type pe : putative enzyme
YP_002400657.1	Evidence 5 : No homology to any previously reported sequences
YP_002400658.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002400659.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002400660.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400661.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400662.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400663.1	IrgA-homologue adhesin (Iha); TonB-dependent; acts as a specific receptor of enterobactin; fur-regulated; urovirulence factor
YP_002400664.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400665.1	Evidence 6 : Doubtful CDS
YP_002400666.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4313071, 6456229, 7044820, 7042696, 6749806; Product type rc : receptor
YP_002400667.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3275632, 10064136; Product type e : enzyme
YP_002400668.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3087960; Product type e : enzyme
YP_002400669.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3087960; Product type e : enzyme
YP_002400670.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3087960; Product type e : enzyme
YP_002400671.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400672.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400673.1	Evidence 5 : No homology to any previously reported sequences
YP_002400674.1	Evidence 5 : No homology to any previously reported sequences
YP_002400675.1	catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid
YP_002400676.1	catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein
YP_002400677.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme
YP_002400678.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400679.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15743943; Product type pm : putative membrane component
YP_002400680.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400681.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400682.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type r : regulator
YP_002400683.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400684.1	Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
YP_002400685.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1370290; Product type pr : putative regulator
YP_002400686.1	two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm
YP_002400687.1	copper binding protein required for copper tolerance; involved in resistance toward heavy metals
YP_002400688.1	functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB
YP_002400689.1	catalyzes the formation of fumarate from aspartate
YP_002400690.1	F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein
YP_002400691.1	uncharacterized member of the APC superfamily of amino acid transporters; unknown function
YP_002400692.1	10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring
YP_002400693.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth
YP_002400694.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400695.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400696.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019591, 10629195; Product type pe : putative enzyme
YP_002400697.1	Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA
YP_002400698.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98344100, 9677290; Product type lp : lipoprotein
YP_002400699.1	member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations
YP_002400700.1	lipocalin; globomycin-sensitive outer membrane lipoprotein
YP_002400701.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92212899, 97464439, 99421326, 10595535, 6795623, 7041115, 9819201; Product type e : enzyme
YP_002400702.1	in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane
YP_002400703.1	part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB
YP_002400704.1	part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB
YP_002400705.1	part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB
YP_002400706.1	lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA
YP_002400707.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400708.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400709.1	catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine
YP_002400710.1	EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity
YP_002400711.1	3'-5' exoribonuclease specific for small oligoribonuclotides
YP_002400712.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : putative carrier
YP_002400713.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400714.1	possibly involved in cell wall synthesis
YP_002400715.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21348478, 87242501, 1594459, 7511774; Product type e : enzyme
YP_002400716.1	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
YP_002400717.1	IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity
YP_002400718.1	Stimulates the elongation of poly(A) tails
YP_002400719.1	involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein
YP_002400720.1	with HflC inhibits proteolysis of lambda cII protein by FtsH
YP_002400721.1	with HflK inhibits proteolysis of lambda cII protein by FtsH
YP_002400722.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400723.1	catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis
YP_002400724.1	negatively regulates the transcription of genes upregulated by nitrosative stress
YP_002400725.1	3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs
YP_002400726.1	Specifically methylates the ribose of guanosine 2251 in 23S rRNA
YP_002400727.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400728.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400729.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400730.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400731.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400732.1	catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA
YP_002400733.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400734.1	in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility
YP_002400735.1	YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo
YP_002400736.1	negative regulator of ulaG and ulaABCDEF
YP_002400737.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12644495, 15808744; Product type pe : putative enzyme
YP_002400738.1	membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr
YP_002400739.1	involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake
YP_002400740.1	involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake
YP_002400741.1	catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization
YP_002400742.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9987116
YP_002400743.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400744.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14594833; Product type f : factor
YP_002400745.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14594833; Product type h : extrachromosomal origin
YP_002400746.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002400747.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11053371; Product type pf : putative factor
YP_002400748.1	Evidence 6 : Doubtful CDS
YP_002400749.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400750.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400751.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400752.1	Evidence 5 : No homology to any previously reported sequences
YP_002400753.1	Evidence 5 : No homology to any previously reported sequences
YP_002400754.1	Evidence 5 : No homology to any previously reported sequences
YP_002400755.1	Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate
YP_002400756.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1508157; Product type e : enzyme
YP_002400757.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400758.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002400759.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002400760.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400761.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400762.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400763.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002400764.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002400765.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400766.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400767.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400768.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002400769.1	Evidence 2b : Function of strongly homologous gene; Product type t : transporter
YP_002400770.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin
YP_002400771.1	Evidence 7 : Gene remnant
YP_002400772.1	Evidence 7 : Gene remnant
YP_002400773.1	Evidence 2b : Function of strongly homologous gene; Product type rc : receptor
YP_002400774.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400775.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400776.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400777.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400778.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400779.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 10678953; Product type prc : putative receptor
YP_002400780.1	Evidence 5 : No homology to any previously reported sequences
YP_002400781.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400782.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400783.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400784.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400785.1	Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import
YP_002400786.1	Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8807793; Product type m : membrane component
YP_002400787.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400788.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3301805, 1569007, 8349544; Product type pr : putative regulator
YP_002400789.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1569007; Product type pt : putative transporter
YP_002400790.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400791.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002400792.1	UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway
YP_002400793.1	catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
YP_002400794.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400795.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
YP_002400796.1	binds single-stranded DNA at the primosome assembly site
YP_002400797.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
YP_002400798.1	in Escherichia coli this protein is wrapped around the base of the L1 stalk
YP_002400799.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400800.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400801.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400802.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400803.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400804.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400805.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400806.1	catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_002400807.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400808.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8559074; Product type ps : putative structure
YP_002400809.1	FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YP_002400810.1	involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine
YP_002400811.1	Evidence 5 : No homology to any previously reported sequences
YP_002400812.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400813.1	Involved in anaerobic NO protection and iron metabolism
YP_002400814.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400815.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14747727; Product type e : enzyme
YP_002400816.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20088838; Product type pr : putative regulator
YP_002400817.1	periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate
YP_002400818.1	catalyzes the formation of AMP from adenosine-3',5'-bisphosphate
YP_002400819.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pr : putative regulator
YP_002400820.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400821.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400822.1	this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress
YP_002400823.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400824.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400825.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400826.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400827.1	catalyzes the hydrolysis of pyrophosphate to phosphate
YP_002400828.1	Evidence 5 : No homology to any previously reported sequences
YP_002400829.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pt : putative transporter
YP_002400830.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400831.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400832.1	catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate
YP_002400833.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96404780, 2843822, 7984428, 8808921; Product type e : enzyme
YP_002400834.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400835.1	protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD
YP_002400836.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1761034, 8499452, 10393541; Product type c : carrier
YP_002400837.1	activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions
YP_002400838.1	Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates
YP_002400839.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264345, 93302496, 8083158, 8421692; Product type e : enzyme
YP_002400840.1	phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel
YP_002400841.1	regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon
YP_002400842.1	P-type ATPase involved in magnesium influx
YP_002400843.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12515541, 10493123, 10595546, 9298646; Product type pe : putative enzyme
YP_002400844.1	involved in the allosteric regulation of aspartate carbamoyltransferase
YP_002400845.1	catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis
YP_002400846.1	Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide
YP_002400847.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400848.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400849.1	catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway
YP_002400850.1	reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP
YP_002400851.1	catalyzes the degradation of arginine to citruline and ammonia
YP_002400852.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11115104
YP_002400853.1	catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase; when both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III
YP_002400854.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400855.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400856.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type m : membrane component
YP_002400857.1	valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain
YP_002400858.1	binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB
YP_002400859.1	catalyzes the removal of N-terminal amino acids preferably leucine from various peptides
YP_002400860.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400861.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400862.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400863.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9119199, 98324983, 9658018; Product type r : regulator
YP_002400864.1	Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate
YP_002400865.1	NAD-binding
YP_002400866.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87310381, 93139975, 98324983, 9658018, 14832279; Product type e : enzyme
YP_002400867.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12147722; Product type pe : putative enzyme
YP_002400868.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400869.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400870.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002400871.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400872.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15766797, 6281654; Product type h : extrachromosomal origin
YP_002400873.1	Evidence 6 : Doubtful CDS
YP_002400874.1	Evidence 7 : Gene remnant; Product type pe : putative enzyme
YP_002400875.1	Evidence 5 : No homology to any previously reported sequences
YP_002400876.1	Evidence 5 : No homology to any previously reported sequences
YP_002400877.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400878.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14702297; Product type t : transporter
YP_002400879.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002400880.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002400881.1	Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA
YP_002400882.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1406277; Product type r : regulator
YP_002400883.1	Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
YP_002400884.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400885.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002400886.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
YP_002400887.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400888.1	Part of the FecBCDE citrate-dependent iron (III) transport system
YP_002400889.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400890.1	Ferric citrate binds FecA and is transported across the outer membrane while transmits a signal across the cytoplasmic membrane protein FecR. FecR transmits a signal across the membrane and activates the cytoplasmic FecI that directs the RNA polymerase to express the fecABCDE operon (which encodes the ferric citrate outer membrane receptor and the ferric citrate ABC transporter), as well as fecIR. FecD is one of two (along with FecC) integral membrane protein components of the iron dicitrate ABC transporter.
YP_002400891.1	part of the FecBCDE citrate-dependent iron (III) transport system
YP_002400892.1	part of the ABC transporter involved in the uptake of citrate-dependent Fe(3+)
YP_002400893.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90105402, 91072220, 92269759, 2836368; Product type t : transporter
YP_002400894.1	with FecA forms the FecAR signal transduction system; ferric citrate binds FecA and transmits a signal across the outer membrane to FecR. FecR transmits a signal across the cytoplasmic membrane and activates the sigma 70 protein FecI that directs the RNA polymerase to express the fecABCDE operon
YP_002400895.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor regulates the genes for iron dicitrate transport
YP_002400896.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002400897.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002400898.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400899.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400900.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400901.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400902.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400903.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400904.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400905.1	Evidence 2b : Function of strongly homologous gene; PubMedId : 1956303, 8145648, 1484495; Product type f : factor
YP_002400906.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002400907.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400908.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400909.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400910.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400911.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20392470, 97257509, 99212225, 2661530, 9298646; Product type h : extrachromosomal origin
YP_002400912.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400913.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400914.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400915.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400916.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7519596; Product type pf : putative factor
YP_002400917.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11053371; Product type pf : putative factor
YP_002400918.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin
YP_002400919.1	Evidence 6 : Doubtful CDS
YP_002400920.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14594833; Product type h : extrachromosomal origin
YP_002400921.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14594833; Product type h : extrachromosomal origin
YP_002400922.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400923.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400924.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400925.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400926.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400927.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15743943; Product type t : transporter
YP_002400928.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400929.1	inversion of on/off regulator of fimA
YP_002400930.1	inversion of on/off regulator of fimA
YP_002400931.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6146599, 6147250, 90220509, 93106965, 2858471, 6123483; Product type s : structure
YP_002400932.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12897022, 11673421, 6147250; Product type s : structure
YP_002400933.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20450729, 90220509, 93155127, 93391362, 1363735, 8104335, 8636962, 9783748; Product type f : factor
YP_002400934.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1970114, 89056689, 93155127, 93391362, 1971261, 2890081, 2900235, 790547; Product type s : structure
YP_002400935.1	catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate
YP_002400936.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73203083, 77222076, 14401695; Product type e : enzyme
YP_002400937.1	regulates the expression of uxuBA
YP_002400938.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400939.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400940.1	Evidence 6 : Doubtful CDS
YP_002400941.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400942.1	involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response
YP_002400943.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9108149, 2642743; Product type e : enzyme
YP_002400944.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8412658, 1409708; Product type e : enzyme
YP_002400945.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9837717, 10373579, 10733903, 8412658; Product type e : enzyme
YP_002400946.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400947.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14696199; Product type pe : putative enzyme
YP_002400948.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400949.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400950.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20015410, 89034150, 91317710, 10466731, 2033064, 6213619, 6402709, 8384293; Product type r : regulator
YP_002400951.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400952.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400953.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400954.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : putative transporter
YP_002400955.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400956.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400957.1	catalyzes the transfer of phosphoglycerol to the glucan backbone
YP_002400958.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400959.1	acts to load the DnaB helicase onto the initiation site during DNA replication
YP_002400960.1	This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'
YP_002400961.2	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400962.1	Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : putative membrane component
YP_002400963.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002400964.1	Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme
YP_002400965.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400966.1	regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin
YP_002400967.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11931550, 14756576, 3323834, 9990318; Product type c : carrier
YP_002400968.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400969.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400970.1	16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit
YP_002400971.1	with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB
YP_002400972.1	alanine acetyltransferase that specifically acetylates ribosomal protein S18
YP_002400973.1	manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily
YP_002400974.1	stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein
YP_002400975.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1317380, 8253679, 9298646, 9600841; Product type cp : cell process
YP_002400976.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400977.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400978.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400979.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
YP_002400980.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400981.1	catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate
YP_002400982.1	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
YP_002400983.1	catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose
YP_002400984.1	catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate
YP_002400985.1	Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
YP_002400986.1	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins
YP_002400987.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2684780
YP_002400988.1	catalyzes the formation of serine from O-phosphoserine
YP_002400989.1	Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents
YP_002400990.1	catalyzes the formation of NAD(+) from nicotinamide ribonucleotide
YP_002400991.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400992.1	Evidence 4 : Homologs of previously reported genes of unknown function
YP_002400993.1	ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence
YP_002400994.1	catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan
YP_002400995.1	When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription
YP_002400996.1	pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog
YP_002400997.1	catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate
YP_002400998.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20264525, 20309711, 93194823, 96405618, 8449900; Product type r : regulator
YP_002400999.1	Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3531171, 8449900
YP_002401000.1	response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation
YP_002401001.1	part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation
YP_002401002.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88216172, 2835585, 2984198, 3531171; Product type m : membrane component
YP_002401003.1	Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15028693, 21167794, 21317451, 91008980, 91358353, 92380937, 9514749, 9632255, 2984198, 7565118, 9298646; Product type r : regulator
YP_002401004.1	member of the SPOUT superfamily of methyltransferases
YP_002401005.1	involved in threonine biosynthesis; controls the expression of the thrLABC operon