-- dump date   	20140619_082051
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
585397000001	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
585397000002	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
585397000003	putative catalytic residues [active]
585397000004	putative nucleotide binding site [chemical binding]; other site
585397000005	putative aspartate binding site [chemical binding]; other site
585397000006	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
585397000007	dimer interface [polypeptide binding]; other site
585397000008	putative threonine allosteric regulatory site; other site
585397000009	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
585397000010	putative threonine allosteric regulatory site; other site
585397000011	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
585397000012	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
585397000013	homoserine kinase; Region: thrB; TIGR00191
585397000014	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
585397000015	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
585397000016	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
585397000017	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397000018	catalytic residue [active]
585397000019	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
585397000020	hypothetical protein; Validated; Region: PRK02101
585397000021	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
585397000022	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
585397000023	transaldolase-like protein; Provisional; Region: PTZ00411
585397000024	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
585397000025	active site
585397000026	dimer interface [polypeptide binding]; other site
585397000027	catalytic residue [active]
585397000028	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
585397000029	MPT binding site; other site
585397000030	trimer interface [polypeptide binding]; other site
585397000031	hypothetical protein; Provisional; Region: PRK10659
585397000032	hypothetical protein; Provisional; Region: PRK10236
585397000033	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
585397000034	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
585397000035	hypothetical protein; Provisional; Region: PRK10154
585397000036	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
585397000037	Nucleotide-binding domain of human HSPA9, Escherichia coli DnaK, and similar proteins; Region: HSPA9-like_NBD; cd11733
585397000038	nucleotide binding site [chemical binding]; other site
585397000039	NEF interaction site [polypeptide binding]; other site
585397000040	SBD interface [polypeptide binding]; other site
585397000041	chaperone protein DnaJ; Provisional; Region: PRK10767
585397000042	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
585397000043	HSP70 interaction site [polypeptide binding]; other site
585397000044	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
585397000045	substrate binding site [polypeptide binding]; other site
585397000046	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
585397000047	Zn binding sites [ion binding]; other site
585397000048	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
585397000049	dimer interface [polypeptide binding]; other site
585397000050	Nucleoside-specific channel-forming protein, Tsx; Region: Channel_Tsx; pfam03502
585397000051	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
585397000052	Sulfatase; Region: Sulfatase; pfam00884
585397000053	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
585397000054	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
585397000055	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397000056	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
585397000057	putative dimerization interface [polypeptide binding]; other site
585397000058	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
585397000059	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
585397000060	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
585397000061	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
585397000062	active site
585397000063	Riboflavin kinase; Region: Flavokinase; smart00904
585397000064	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
585397000065	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
585397000066	HIGH motif; other site
585397000067	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
585397000068	active site
585397000069	KMSKS motif; other site
585397000070	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
585397000071	tRNA binding surface [nucleotide binding]; other site
585397000072	anticodon binding site; other site
585397000073	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
585397000074	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
585397000075	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
585397000076	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
585397000077	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
585397000078	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
585397000079	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
585397000080	active site
585397000081	tetramer interface [polypeptide binding]; other site
585397000082	Protein of unknown function (DUF805); Region: DUF805; pfam05656
585397000083	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
585397000084	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
585397000085	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
585397000086	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
585397000087	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
585397000088	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
585397000089	catalytic site [active]
585397000090	subunit interface [polypeptide binding]; other site
585397000091	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
585397000092	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
585397000093	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
585397000094	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
585397000095	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
585397000096	ATP-grasp domain; Region: ATP-grasp_4; cl17255
585397000097	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
585397000098	IMP binding site; other site
585397000099	dimer interface [polypeptide binding]; other site
585397000100	interdomain contacts; other site
585397000101	partial ornithine binding site; other site
585397000102	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
585397000103	carnitine operon protein CaiE; Provisional; Region: PRK13627
585397000104	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
585397000105	putative trimer interface [polypeptide binding]; other site
585397000106	putative metal binding site [ion binding]; other site
585397000107	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
585397000108	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
585397000109	substrate binding site [chemical binding]; other site
585397000110	oxyanion hole (OAH) forming residues; other site
585397000111	trimer interface [polypeptide binding]; other site
585397000112	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
585397000113	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
585397000114	acyl-activating enzyme (AAE) consensus motif; other site
585397000115	putative AMP binding site [chemical binding]; other site
585397000116	putative active site [active]
585397000117	putative CoA binding site [chemical binding]; other site
585397000118	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
585397000119	CoA-transferase family III; Region: CoA_transf_3; pfam02515
585397000120	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
585397000121	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
585397000122	active site
585397000123	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
585397000124	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
585397000125	Ligand binding site [chemical binding]; other site
585397000126	Electron transfer flavoprotein domain; Region: ETF; pfam01012
585397000127	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
585397000128	Electron transfer flavoprotein domain; Region: ETF; smart00893
585397000129	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
585397000130	putative oxidoreductase FixC; Provisional; Region: PRK10157
585397000131	ferredoxin-like protein FixX; Provisional; Region: PRK15449
585397000132	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397000133	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
585397000134	putative substrate translocation pore; other site
585397000135	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
585397000136	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
585397000137	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
585397000138	TrkA-N domain; Region: TrkA_N; pfam02254
585397000139	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
585397000140	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
585397000141	folate binding site [chemical binding]; other site
585397000142	NADP+ binding site [chemical binding]; other site
585397000143	Post-segregation antitoxin CcdA; Region: CcdA; pfam07362
585397000144	CcdB protein; Region: CcdB; pfam01845
585397000145	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
585397000146	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
585397000147	active site
585397000148	metal binding site [ion binding]; metal-binding site
585397000149	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
585397000150	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
585397000151	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
585397000152	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
585397000153	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
585397000154	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
585397000155	SurA N-terminal domain; Region: SurA_N; pfam09312
585397000156	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
585397000157	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
585397000158	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
585397000159	OstA-like protein; Region: OstA; pfam03968
585397000160	Organic solvent tolerance protein; Region: OstA_C; pfam04453
585397000161	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
585397000162	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
585397000163	putative metal binding site [ion binding]; other site
585397000164	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
585397000165	HSP70 interaction site [polypeptide binding]; other site
585397000166	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
585397000167	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
585397000168	active site
585397000169	ATP-dependent helicase HepA; Validated; Region: PRK04914
585397000170	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585397000171	ATP binding site [chemical binding]; other site
585397000172	putative Mg++ binding site [ion binding]; other site
585397000173	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585397000174	nucleotide binding region [chemical binding]; other site
585397000175	ATP-binding site [chemical binding]; other site
585397000176	DNA polymerase II; Reviewed; Region: PRK05762
585397000177	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
585397000178	active site
585397000179	catalytic site [active]
585397000180	substrate binding site [chemical binding]; other site
585397000181	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
585397000182	active site
585397000183	metal-binding site
585397000184	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
585397000185	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
585397000186	intersubunit interface [polypeptide binding]; other site
585397000187	active site
585397000188	Zn2+ binding site [ion binding]; other site
585397000189	L-arabinose isomerase; Provisional; Region: PRK02929
585397000190	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
585397000191	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
585397000192	trimer interface [polypeptide binding]; other site
585397000193	putative substrate binding site [chemical binding]; other site
585397000194	putative metal binding site [ion binding]; other site
585397000195	ribulokinase; Provisional; Region: PRK04123
585397000196	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
585397000197	N- and C-terminal domain interface [polypeptide binding]; other site
585397000198	active site
585397000199	MgATP binding site [chemical binding]; other site
585397000200	catalytic site [active]
585397000201	metal binding site [ion binding]; metal-binding site
585397000202	carbohydrate binding site [chemical binding]; other site
585397000203	homodimer interface [polypeptide binding]; other site
585397000204	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
585397000205	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
585397000206	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397000207	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397000208	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
585397000209	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
585397000210	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
585397000211	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
585397000212	Walker A/P-loop; other site
585397000213	ATP binding site [chemical binding]; other site
585397000214	Q-loop/lid; other site
585397000215	ABC transporter signature motif; other site
585397000216	Walker B; other site
585397000217	D-loop; other site
585397000218	H-loop/switch region; other site
585397000219	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
585397000220	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397000221	dimer interface [polypeptide binding]; other site
585397000222	conserved gate region; other site
585397000223	putative PBP binding loops; other site
585397000224	ABC-ATPase subunit interface; other site
585397000225	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397000226	dimer interface [polypeptide binding]; other site
585397000227	conserved gate region; other site
585397000228	putative PBP binding loops; other site
585397000229	ABC-ATPase subunit interface; other site
585397000230	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
585397000231	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
585397000232	transcriptional regulator SgrR; Provisional; Region: PRK13626
585397000233	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
585397000234	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
585397000235	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
585397000236	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
585397000237	substrate binding site [chemical binding]; other site
585397000238	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
585397000239	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
585397000240	substrate binding site [chemical binding]; other site
585397000241	ligand binding site [chemical binding]; other site
585397000242	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
585397000243	tartrate dehydrogenase; Region: TTC; TIGR02089
585397000244	2-isopropylmalate synthase; Validated; Region: PRK00915
585397000245	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
585397000246	active site
585397000247	catalytic residues [active]
585397000248	metal binding site [ion binding]; metal-binding site
585397000249	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
585397000250	leu operon leader peptide; Provisional; Region: PRK09925
585397000251	fragment of DNA-binding transcriptional activator (part 1);Evidence 7 : Gene remnant; Product type r : regulator
585397000252	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397000253	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397000254	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397000255	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397000256	fragment of DNA-binding transcriptional activator (part 2);Evidence 7 : Gene remnant; Product type r : regulator
585397000257	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
585397000258	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
585397000259	PYR/PP interface [polypeptide binding]; other site
585397000260	dimer interface [polypeptide binding]; other site
585397000261	TPP binding site [chemical binding]; other site
585397000262	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
585397000263	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
585397000264	TPP-binding site [chemical binding]; other site
585397000265	dimer interface [polypeptide binding]; other site
585397000266	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
585397000267	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
585397000268	putative valine binding site [chemical binding]; other site
585397000269	dimer interface [polypeptide binding]; other site
585397000270	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
585397000271	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
585397000272	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585397000273	DNA binding site [nucleotide binding]
585397000274	domain linker motif; other site
585397000275	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
585397000276	dimerization interface [polypeptide binding]; other site
585397000277	ligand binding site [chemical binding]; other site
585397000278	mraZ protein; Region: TIGR00242
585397000279	MraZ protein; Region: MraZ; pfam02381
585397000280	MraZ protein; Region: MraZ; pfam02381
585397000281	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
585397000282	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
585397000283	cell division protein FtsL; Provisional; Region: PRK10772
585397000284	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
585397000285	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
585397000286	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
585397000287	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
585397000288	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
585397000289	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
585397000290	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
585397000291	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
585397000292	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
585397000293	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
585397000294	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
585397000295	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
585397000296	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
585397000297	Mg++ binding site [ion binding]; other site
585397000298	putative catalytic motif [active]
585397000299	putative substrate binding site [chemical binding]; other site
585397000300	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
585397000301	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
585397000302	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
585397000303	cell division protein FtsW; Provisional; Region: PRK10774
585397000304	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
585397000305	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
585397000306	active site
585397000307	homodimer interface [polypeptide binding]; other site
585397000308	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
585397000309	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
585397000310	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
585397000311	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
585397000312	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
585397000313	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
585397000314	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
585397000315	cell division protein FtsQ; Provisional; Region: PRK10775
585397000316	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
585397000317	Cell division protein FtsQ; Region: FtsQ; pfam03799
585397000318	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
585397000319	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
585397000320	Cell division protein FtsA; Region: FtsA; pfam14450
585397000321	cell division protein FtsZ; Validated; Region: PRK09330
585397000322	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
585397000323	nucleotide binding site [chemical binding]; other site
585397000324	SulA interaction site; other site
585397000325	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
585397000326	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
585397000327	SecA regulator SecM; Provisional; Region: PRK02943
585397000328	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
585397000329	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
585397000330	SEC-C motif; Region: SEC-C; pfam02810
585397000331	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
585397000332	active site
585397000333	8-oxo-dGMP binding site [chemical binding]; other site
585397000334	nudix motif; other site
585397000335	metal binding site [ion binding]; metal-binding site
585397000336	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
585397000337	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
585397000338	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
585397000339	CoA-binding site [chemical binding]; other site
585397000340	ATP-binding [chemical binding]; other site
585397000341	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
585397000342	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
585397000343	active site
585397000344	type IV pilin biogenesis protein; Provisional; Region: PRK10573
585397000345	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
585397000346	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
585397000347	hypothetical protein; Provisional; Region: PRK10436
585397000348	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
585397000349	Walker A motif; other site
585397000350	ATP binding site [chemical binding]; other site
585397000351	Walker B motif; other site
585397000352	putative major pilin subunit; Provisional; Region: PRK10574
585397000353	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
585397000354	Pilin (bacterial filament); Region: Pilin; pfam00114
585397000355	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
585397000356	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
585397000357	dimerization interface [polypeptide binding]; other site
585397000358	active site
585397000359	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
585397000360	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
585397000361	amidase catalytic site [active]
585397000362	Zn binding residues [ion binding]; other site
585397000363	substrate binding site [chemical binding]; other site
585397000364	regulatory protein AmpE; Provisional; Region: PRK10987
585397000365	aromatic amino acid transporter; Provisional; Region: PRK10238
585397000366	Protein of unknown function (DUF796); Region: DUF796; cl01226
585397000367	S-type Pyocin; Region: Pyocin_S; pfam06958
585397000368	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
585397000369	active site
585397000370	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
585397000371	conserved hypothetical protein; uropathogenic specific protein (usp-like) (fragment);Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10702359
585397000372	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
585397000373	uropathogenic specific protein (usp-like) (fragment);Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10702359
585397000374	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
585397000375	Transcriptional regulators [Transcription]; Region: FadR; COG2186
585397000376	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585397000377	DNA-binding site [nucleotide binding]; DNA binding site
585397000378	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
585397000379	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
585397000380	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
585397000381	dimer interface [polypeptide binding]; other site
585397000382	TPP-binding site [chemical binding]; other site
585397000383	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
585397000384	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
585397000385	E3 interaction surface; other site
585397000386	lipoyl attachment site [posttranslational modification]; other site
585397000387	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
585397000388	E3 interaction surface; other site
585397000389	lipoyl attachment site [posttranslational modification]; other site
585397000390	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
585397000391	E3 interaction surface; other site
585397000392	lipoyl attachment site [posttranslational modification]; other site
585397000393	e3 binding domain; Region: E3_binding; pfam02817
585397000394	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
585397000395	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
585397000396	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
585397000397	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585397000398	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
585397000399	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
585397000400	Protein of unknown function (DUF3106); Region: DUF3106; pfam11304
585397000401	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
585397000402	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
585397000403	substrate binding site [chemical binding]; other site
585397000404	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
585397000405	substrate binding site [chemical binding]; other site
585397000406	ligand binding site [chemical binding]; other site
585397000407	hypothetical protein; Provisional; Region: PRK05248
585397000408	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
585397000409	spermidine synthase; Provisional; Region: PRK00811
585397000410	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397000411	S-adenosylmethionine binding site [chemical binding]; other site
585397000412	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
585397000413	multicopper oxidase; Provisional; Region: PRK10965
585397000414	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
585397000415	Multicopper oxidase; Region: Cu-oxidase; pfam00394
585397000416	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
585397000417	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
585397000418	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
585397000419	Trp docking motif [polypeptide binding]; other site
585397000420	putative active site [active]
585397000421	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
585397000422	active site
585397000423	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
585397000424	active site clefts [active]
585397000425	zinc binding site [ion binding]; other site
585397000426	dimer interface [polypeptide binding]; other site
585397000427	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
585397000428	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
585397000429	Walker A/P-loop; other site
585397000430	ATP binding site [chemical binding]; other site
585397000431	Q-loop/lid; other site
585397000432	ABC transporter signature motif; other site
585397000433	Walker B; other site
585397000434	D-loop; other site
585397000435	H-loop/switch region; other site
585397000436	inner membrane transport permease; Provisional; Region: PRK15066
585397000437	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
585397000438	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
585397000439	active pocket/dimerization site; other site
585397000440	active site
585397000441	phosphorylation site [posttranslational modification]
585397000442	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
585397000443	putative active site [active]
585397000444	putative metal binding site [ion binding]; other site
585397000445	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
585397000446	tetramerization interface [polypeptide binding]; other site
585397000447	active site
585397000448	Uncharacterized conserved protein [Function unknown]; Region: COG5464
585397000449	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
585397000450	pantoate--beta-alanine ligase; Region: panC; TIGR00018
585397000451	Pantoate-beta-alanine ligase; Region: PanC; cd00560
585397000452	active site
585397000453	ATP-binding site [chemical binding]; other site
585397000454	pantoate-binding site; other site
585397000455	HXXH motif; other site
585397000456	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
585397000457	oligomerization interface [polypeptide binding]; other site
585397000458	active site
585397000459	metal binding site [ion binding]; metal-binding site
585397000460	fragment of putative exported protein yadC, putative fimbrial-like adhesin protein (partial);Evidence 7 : Gene remnant; Product type ps : putative structure
585397000461	putative fimbrial protein StaF; Provisional; Region: PRK15262
585397000462	putative fimbrial protein StaE; Provisional; Region: PRK15263
585397000463	Fimbrial protein; Region: Fimbrial; cl01416
585397000464	putative fimbrial outer membrane usher protein; Provisional; Region: PRK09828
585397000465	PapC N-terminal domain; Region: PapC_N; pfam13954
585397000466	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585397000467	PapC C-terminal domain; Region: PapC_C; pfam13953
585397000468	putative chaperone protein EcpD; Provisional; Region: PRK09926
585397000469	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585397000470	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
585397000471	Fimbrial protein; Region: Fimbrial; cl01416
585397000472	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
585397000473	catalytic center binding site [active]
585397000474	ATP binding site [chemical binding]; other site
585397000475	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
585397000476	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
585397000477	active site
585397000478	NTP binding site [chemical binding]; other site
585397000479	metal binding triad [ion binding]; metal-binding site
585397000480	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
585397000481	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
585397000482	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
585397000483	tRNA synthetases class I (E and Q), catalytic domain; Region: tRNA-synt_1c; pfam00749
585397000484	active site
585397000485	nucleotide binding site [chemical binding]; other site
585397000486	HIGH motif; other site
585397000487	KMSKS motif; other site
585397000488	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
585397000489	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
585397000490	2'-5' RNA ligase; Provisional; Region: PRK15124
585397000491	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
585397000492	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
585397000493	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
585397000494	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585397000495	ATP binding site [chemical binding]; other site
585397000496	putative Mg++ binding site [ion binding]; other site
585397000497	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585397000498	nucleotide binding region [chemical binding]; other site
585397000499	ATP-binding site [chemical binding]; other site
585397000500	Helicase associated domain (HA2) Add an annotation; Region: HA2; smart00847
585397000501	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
585397000502	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
585397000503	Transglycosylase; Region: Transgly; pfam00912
585397000504	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
585397000505	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
585397000506	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585397000507	N-terminal plug; other site
585397000508	ligand-binding site [chemical binding]; other site
585397000509	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
585397000510	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
585397000511	Walker A/P-loop; other site
585397000512	ATP binding site [chemical binding]; other site
585397000513	Q-loop/lid; other site
585397000514	ABC transporter signature motif; other site
585397000515	Walker B; other site
585397000516	D-loop; other site
585397000517	H-loop/switch region; other site
585397000518	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
585397000519	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
585397000520	siderophore binding site; other site
585397000521	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
585397000522	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
585397000523	ABC-ATPase subunit  interface; other site
585397000524	dimer interface [polypeptide binding]; other site
585397000525	putative PBP binding regions; other site
585397000526	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
585397000527	ABC-ATPase subunit  interface; other site
585397000528	dimer interface [polypeptide binding]; other site
585397000529	putative PBP binding regions; other site
585397000530	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
585397000531	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
585397000532	inhibitor-cofactor binding pocket; inhibition site
585397000533	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397000534	catalytic residue [active]
585397000535	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
585397000536	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
585397000537	Cl- selectivity filter; other site
585397000538	Cl- binding residues [ion binding]; other site
585397000539	pore gating glutamate residue; other site
585397000540	dimer interface [polypeptide binding]; other site
585397000541	H+/Cl- coupling transport residue; other site
585397000542	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
585397000543	hypothetical protein; Provisional; Region: PRK10578
585397000544	UPF0126 domain; Region: UPF0126; pfam03458
585397000545	UPF0126 domain; Region: UPF0126; pfam03458
585397000546	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
585397000547	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
585397000548	cobalamin binding residues [chemical binding]; other site
585397000549	putative BtuC binding residues; other site
585397000550	dimer interface [polypeptide binding]; other site
585397000551	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
585397000552	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
585397000553	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
585397000554	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
585397000555	Zn2+ binding site [ion binding]; other site
585397000556	Mg2+ binding site [ion binding]; other site
585397000557	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
585397000558	serine endoprotease; Provisional; Region: PRK10942
585397000559	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
585397000560	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
585397000561	protein binding site [polypeptide binding]; other site
585397000562	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
585397000563	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
585397000564	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
585397000565	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
585397000566	hypothetical protein; Provisional; Region: PRK13677
585397000567	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
585397000568	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
585397000569	trimer interface [polypeptide binding]; other site
585397000570	active site
585397000571	substrate binding site [chemical binding]; other site
585397000572	CoA binding site [chemical binding]; other site
585397000573	PII uridylyl-transferase; Provisional; Region: PRK05007
585397000574	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
585397000575	metal binding triad; other site
585397000576	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
585397000577	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
585397000578	Zn2+ binding site [ion binding]; other site
585397000579	Mg2+ binding site [ion binding]; other site
585397000580	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
585397000581	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
585397000582	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
585397000583	active site
585397000584	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
585397000585	rRNA interaction site [nucleotide binding]; other site
585397000586	S8 interaction site; other site
585397000587	putative laminin-1 binding site; other site
585397000588	elongation factor Ts; Provisional; Region: tsf; PRK09377
585397000589	UBA/TS-N domain; Region: UBA; pfam00627
585397000590	Elongation factor TS; Region: EF_TS; pfam00889
585397000591	Elongation factor TS; Region: EF_TS; pfam00889
585397000592	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
585397000593	putative nucleotide binding site [chemical binding]; other site
585397000594	uridine monophosphate binding site [chemical binding]; other site
585397000595	homohexameric interface [polypeptide binding]; other site
585397000596	ribosome recycling factor; Reviewed; Region: frr; PRK00083
585397000597	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
585397000598	hinge region; other site
585397000599	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
585397000600	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
585397000601	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
585397000602	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
585397000603	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
585397000604	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
585397000605	catalytic residue [active]
585397000606	putative FPP diphosphate  binding site; other site
585397000607	putative FPP binding hydrophobic cleft; other site
585397000608	dimer interface [polypeptide binding]; other site
585397000609	putative IPP diphosphate binding site; other site
585397000610	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
585397000611	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
585397000612	zinc metallopeptidase RseP; Provisional; Region: PRK10779
585397000613	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
585397000614	active site
585397000615	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
585397000616	protein binding site [polypeptide binding]; other site
585397000617	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
585397000618	putative substrate binding region [chemical binding]; other site
585397000619	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
585397000620	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
585397000621	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
585397000622	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
585397000623	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
585397000624	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
585397000625	Surface antigen; Region: Bac_surface_Ag; pfam01103
585397000626	periplasmic chaperone; Provisional; Region: PRK10780
585397000627	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
585397000628	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
585397000629	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
585397000630	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
585397000631	trimer interface [polypeptide binding]; other site
585397000632	active site
585397000633	UDP-GlcNAc binding site [chemical binding]; other site
585397000634	lipid binding site [chemical binding]; lipid-binding site
585397000635	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
585397000636	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
585397000637	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
585397000638	active site
585397000639	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
585397000640	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
585397000641	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
585397000642	RNA/DNA hybrid binding site [nucleotide binding]; other site
585397000643	active site
585397000644	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
585397000645	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
585397000646	putative active site [active]
585397000647	putative PHP Thumb interface [polypeptide binding]; other site
585397000648	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
585397000649	generic binding surface II; other site
585397000650	generic binding surface I; other site
585397000651	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
585397000652	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
585397000653	lysine decarboxylase LdcC; Provisional; Region: PRK15399
585397000654	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
585397000655	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
585397000656	homodimer interface [polypeptide binding]; other site
585397000657	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397000658	catalytic residue [active]
585397000659	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
585397000660	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
585397000661	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
585397000662	putative metal binding site [ion binding]; other site
585397000663	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
585397000664	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
585397000665	Ligand Binding Site [chemical binding]; other site
585397000666	TilS substrate binding domain; Region: TilS; pfam09179
585397000667	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
585397000668	Rho-binding antiterminator; Provisional; Region: PRK11625
585397000669	hypothetical protein; Provisional; Region: PRK04964
585397000670	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
585397000671	hypothetical protein; Provisional; Region: PRK09256
585397000672	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
585397000673	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
585397000674	NlpE N-terminal domain; Region: NlpE; pfam04170
585397000675	hypothetical protein; Provisional; Region: PRK11479
585397000676	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
585397000677	prolyl-tRNA synthetase; Provisional; Region: PRK09194
585397000678	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
585397000679	dimer interface [polypeptide binding]; other site
585397000680	motif 1; other site
585397000681	active site
585397000682	motif 2; other site
585397000683	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
585397000684	putative deacylase active site [active]
585397000685	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
585397000686	active site
585397000687	motif 3; other site
585397000688	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
585397000689	anticodon binding site; other site
585397000690	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
585397000691	homodimer interaction site [polypeptide binding]; other site
585397000692	cofactor binding site; other site
585397000693	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
585397000694	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
585397000695	lipoprotein, YaeC family; Region: TIGR00363
585397000696	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397000697	dimer interface [polypeptide binding]; other site
585397000698	conserved gate region; other site
585397000699	ABC-ATPase subunit interface; other site
585397000700	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
585397000701	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
585397000702	Walker A/P-loop; other site
585397000703	ATP binding site [chemical binding]; other site
585397000704	Q-loop/lid; other site
585397000705	ABC transporter signature motif; other site
585397000706	Walker B; other site
585397000707	D-loop; other site
585397000708	H-loop/switch region; other site
585397000709	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
585397000710	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
585397000711	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397000712	active site
585397000713	motif I; other site
585397000714	motif II; other site
585397000715	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
585397000716	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
585397000717	active site
585397000718	catalytic tetrad [active]
585397000719	Transcriptional regulator [Transcription]; Region: LysR; COG0583
585397000720	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397000721	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
585397000722	putative effector binding pocket; other site
585397000723	dimerization interface [polypeptide binding]; other site
585397000724	hypothetical protein; Provisional; Region: PRK05421
585397000725	putative catalytic site [active]
585397000726	putative metal binding site [ion binding]; other site
585397000727	putative phosphate binding site [ion binding]; other site
585397000728	putative catalytic site [active]
585397000729	putative phosphate binding site [ion binding]; other site
585397000730	putative metal binding site [ion binding]; other site
585397000731	Methyltransferase domain; Region: Methyltransf_31; pfam13847
585397000732	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397000733	S-adenosylmethionine binding site [chemical binding]; other site
585397000734	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
585397000735	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
585397000736	N-acetyl-D-glucosamine binding site [chemical binding]; other site
585397000737	catalytic residue [active]
585397000738	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
585397000739	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
585397000740	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
585397000741	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397000742	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
585397000743	RNA/DNA hybrid binding site [nucleotide binding]; other site
585397000744	active site
585397000745	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
585397000746	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
585397000747	active site
585397000748	catalytic site [active]
585397000749	substrate binding site [chemical binding]; other site
585397000750	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
585397000751	fragment of Conserved hypothetical protein Aec31, putative ImpA-related N-termina domain (part 3);Evidence 7 : Gene remnant
585397000752	fragment of Conserved hypothetical protein Aec31, putative ImpA-related N-termina domain (part 2);Evidence 7 : Gene remnant
585397000753	fragment of Conserved hypothetical protein Aec31, putative ImpA-related N-termina domain (part 1);Evidence 7 : Gene remnant
585397000754	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
585397000755	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
585397000756	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
585397000757	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
585397000758	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
585397000759	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
585397000760	type VI secretion-associated protein, VC_A0118 family; Region: VI_minor_1; TIGR03360
585397000761	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
585397000762	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397000763	Walker A motif; other site
585397000764	ATP binding site [chemical binding]; other site
585397000765	Walker B motif; other site
585397000766	arginine finger; other site
585397000767	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397000768	Walker A motif; other site
585397000769	ATP binding site [chemical binding]; other site
585397000770	Walker B motif; other site
585397000771	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
585397000772	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
585397000773	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
585397000774	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
585397000775	type VI secretion lipoprotein, VC_A0113 family; Region: VI_chp_3; TIGR03352
585397000776	type VI secretion system FHA domain protein; Region: VI_FHA; TIGR03354
585397000777	FHA domain; Region: FHA; pfam00498
585397000778	type VI secretion protein, VC_A0111 family; Region: VI_chp_1; TIGR03347
585397000779	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
585397000780	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
585397000781	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
585397000782	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
585397000783	Protein of unknown function (DUF877); Region: DUF877; pfam05943
585397000784	Protein of unknown function (DUF770); Region: DUF770; pfam05591
585397000785	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
585397000786	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
585397000787	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
585397000788	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
585397000789	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
585397000790	Protein of unknown function, DUF538; Region: DUF538; pfam04398
585397000791	Domain of unknown function (DUF4123); Region: DUF4123; pfam13503
585397000792	Protein of unknown function (DUF3304); Region: DUF3304; pfam11745
585397000793	Protein of unknown function (DUF3304); Region: DUF3304; pfam11745
585397000794	Protein of unknown function (DUF3304); Region: DUF3304; pfam11745
585397000795	Protein of unknown function (DUF3304); Region: DUF3304; pfam11745
585397000796	Uncharacterized conserved protein (DUF2235); Region: DUF2235; pfam09994
585397000797	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; cl17880
585397000798	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; cl17880
585397000799	Protein of unknown function (DUF2859); Region: DUF2859; pfam11072
585397000800	C-N hydrolase family amidase; Provisional; Region: PRK10438
585397000801	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
585397000802	putative active site [active]
585397000803	catalytic triad [active]
585397000804	dimer interface [polypeptide binding]; other site
585397000805	multimer interface [polypeptide binding]; other site
585397000806	C-lysozyme inhibitor; Provisional; Region: PRK09993
585397000807	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
585397000808	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
585397000809	active site
585397000810	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
585397000811	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
585397000812	dimer interface [polypeptide binding]; other site
585397000813	active site
585397000814	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
585397000815	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
585397000816	putative active site [active]
585397000817	putative dimer interface [polypeptide binding]; other site
585397000818	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
585397000819	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
585397000820	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
585397000821	NlpC/P60 family; Region: NLPC_P60; pfam00877
585397000822	fragment of conserved hypothetical protein (part 1);Evidence 7 : Gene remnant
585397000823	fragment of conserved hypothetical protein (part 2);Evidence 7 : Gene remnant
585397000824	Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; COG1298
585397000825	FHIPEP family; Region: FHIPEP; pfam00771
585397000826	hypothetical protein; Validated; Region: PRK06778
585397000827	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
585397000828	ligand binding site [chemical binding]; other site
585397000829	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
585397000830	active site
585397000831	DNA polymerase IV; Validated; Region: PRK02406
585397000832	DNA binding site [nucleotide binding]
585397000833	putative antitoxin of the YafO-YafN toxin-antitoxin system; Provisional; Region: PRK09778
585397000834	putative toxin YafO; Provisional; Region: PRK09885
585397000835	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
585397000836	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585397000837	Coenzyme A binding pocket [chemical binding]; other site
585397000838	hypothetical protein; Reviewed; Region: PRK09588
585397000839	release factor H-coupled RctB family protein; Region: release_rtcB; TIGR03073
585397000840	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
585397000841	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
585397000842	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
585397000843	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
585397000844	metal binding site [ion binding]; metal-binding site
585397000845	dimer interface [polypeptide binding]; other site
585397000846	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
585397000847	active site
585397000848	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
585397000849	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
585397000850	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
585397000851	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
585397000852	trimer interface [polypeptide binding]; other site
585397000853	eyelet of channel; other site
585397000854	gamma-glutamyl kinase; Provisional; Region: PRK05429
585397000855	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
585397000856	nucleotide binding site [chemical binding]; other site
585397000857	homotetrameric interface [polypeptide binding]; other site
585397000858	putative phosphate binding site [ion binding]; other site
585397000859	putative allosteric binding site; other site
585397000860	PUA domain; Region: PUA; pfam01472
585397000861	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
585397000862	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
585397000863	putative catalytic cysteine [active]
585397000864	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
585397000865	fragment of conserved hypothetical protein; CP4-57 prophage (part 1);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585397000866	fragment of conserved hypothetical protein; CP4-57 prophage (part 1);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585397000867	fragment of conserved hypothetical protein; CP4-57 prophage (part 3);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585397000868	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
585397000869	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
585397000870	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4951
585397000871	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
585397000872	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585397000873	ATP binding site [chemical binding]; other site
585397000874	putative Mg++ binding site [ion binding]; other site
585397000875	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585397000876	nucleotide binding region [chemical binding]; other site
585397000877	ATP-binding site [chemical binding]; other site
585397000878	hypothetical protein; Provisional; Region: PRK09956
585397000879	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
585397000880	fragment of putative type I restriction-modification system methyltransferase subunit; (hsdM-like) (part 1);Evidence 7 : Gene remnant; Product type e : enzyme
585397000881	putative type I restriction enzyme HindVIIP M protein;Evidence 7 : Gene remnant; PubMedId : 8939428, 11600708; Product type pe : putative enzyme
585397000882	fragment of putative type I restriction-modification system methyltransferase subunit; (hsdM-like) (part 2);Evidence 7 : Gene remnant; Product type e : enzyme
585397000883	fragment of putative lysine aminomutase (partial);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397000884	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
585397000885	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
585397000886	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
585397000887	putative active site [active]
585397000888	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
585397000889	Transposase; Region: DEDD_Tnp_IS110; pfam01548
585397000890	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
585397000891	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
585397000892	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397000893	putative substrate translocation pore; other site
585397000894	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397000895	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
585397000896	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397000897	putative substrate translocation pore; other site
585397000898	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397000899	Transposase IS200 like; Region: Y1_Tnp; pfam01797
585397000900	Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718
585397000901	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
585397000902	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
585397000903	tetrameric interface [polypeptide binding]; other site
585397000904	NAD binding site [chemical binding]; other site
585397000905	catalytic residues [active]
585397000906	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
585397000907	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
585397000908	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397000909	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
585397000910	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
585397000911	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
585397000912	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
585397000913	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
585397000914	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
585397000915	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
585397000916	major facilitator superfamily transporter; Provisional; Region: PRK05122
585397000917	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397000918	putative substrate translocation pore; other site
585397000919	transposase IS91 (part 2);Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
585397000920	transposase IS91 (part 1);Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
585397000921	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
585397000922	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
585397000923	substrate binding site [chemical binding]; other site
585397000924	ATP binding site [chemical binding]; other site
585397000925	Uncharacterized protein conserved in bacteria (DUF2090); Region: DUF2090; pfam09863
585397000926	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3892
585397000927	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
585397000928	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
585397000929	PYR/PP interface [polypeptide binding]; other site
585397000930	dimer interface [polypeptide binding]; other site
585397000931	TPP binding site [chemical binding]; other site
585397000932	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
585397000933	Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003
585397000934	TPP-binding site; other site
585397000935	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
585397000936	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
585397000937	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
585397000938	polyol permease family; Region: 2A0118; TIGR00897
585397000939	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397000940	putative substrate translocation pore; other site
585397000941	Transposase; Region: HTH_Tnp_1; pfam01527
585397000942	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
585397000943	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
585397000944	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
585397000945	Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I; Region: DD_cGKI; cl17044
585397000946	homodimer interface [polypeptide binding]; other site
585397000947	putative GKAP docking site [polypeptide binding]; other site
585397000948	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
585397000949	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
585397000950	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
585397000951	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
585397000952	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
585397000953	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
585397000954	putative active site [active]
585397000955	putative NTP binding site [chemical binding]; other site
585397000956	putative nucleic acid binding site [nucleotide binding]; other site
585397000957	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
585397000958	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
585397000959	aldose 1-epimerase superfamily; Region: Aldose_epim; cl14648
585397000960	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
585397000961	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397000962	putative substrate translocation pore; other site
585397000963	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
585397000964	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
585397000965	substrate binding site [chemical binding]; other site
585397000966	dimer interface [polypeptide binding]; other site
585397000967	ATP binding site [chemical binding]; other site
585397000968	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
585397000969	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
585397000970	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585397000971	fragment of putative NADH-dependent flavin oxidoreductase (partial);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397000972	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
585397000973	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
585397000974	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585397000975	DNA binding residues [nucleotide binding]
585397000976	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397000977	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397000978	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397000979	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397000980	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585397000981	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
585397000982	fragment of putative surface or exported protein (partial);Evidence 7 : Gene remnant; Product type pr : putative regulator
585397000983	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
585397000984	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
585397000985	active site
585397000986	catalytic tetrad [active]
585397000987	Predicted membrane protein [Function unknown]; Region: COG3059
585397000988	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
585397000989	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
585397000990	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
585397000991	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585397000992	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
585397000993	Cupin; Region: Cupin_6; pfam12852
585397000994	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
585397000995	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397000996	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
585397000997	Cysteine-rich domain; Region: CCG; pfam02754
585397000998	Cysteine-rich domain; Region: CCG; pfam02754
585397000999	iron-sulfur cluster-binding protein; Region: TIGR00273
585397001000	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
585397001001	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
585397001002	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
585397001003	Uncharacterized conserved protein [Function unknown]; Region: COG1556
585397001004	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
585397001005	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cl00185
585397001006	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
585397001007	Autotransporter beta-domain; Region: Autotransporter; pfam03797
585397001008	CoA binding domain; Region: CoA_binding; pfam02629
585397001009	CoA-ligase; Region: Ligase_CoA; pfam00549
585397001010	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
585397001011	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
585397001012	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
585397001013	putative substrate binding site [chemical binding]; other site
585397001014	nucleotide binding site [chemical binding]; other site
585397001015	nucleotide binding site [chemical binding]; other site
585397001016	homodimer interface [polypeptide binding]; other site
585397001017	putative deaminase; Validated; Region: PRK06846
585397001018	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
585397001019	active site
585397001020	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
585397001021	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
585397001022	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
585397001023	ligand binding site [chemical binding]; other site
585397001024	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
585397001025	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
585397001026	Walker A/P-loop; other site
585397001027	ATP binding site [chemical binding]; other site
585397001028	Q-loop/lid; other site
585397001029	ABC transporter signature motif; other site
585397001030	Walker B; other site
585397001031	D-loop; other site
585397001032	H-loop/switch region; other site
585397001033	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
585397001034	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585397001035	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585397001036	TM-ABC transporter signature motif; other site
585397001037	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585397001038	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585397001039	TM-ABC transporter signature motif; other site
585397001040	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
585397001041	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
585397001042	putative NAD(P) binding site [chemical binding]; other site
585397001043	putative substrate binding site [chemical binding]; other site
585397001044	catalytic Zn binding site [ion binding]; other site
585397001045	structural Zn binding site [ion binding]; other site
585397001046	dimer interface [polypeptide binding]; other site
585397001047	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
585397001048	hypothetical protein; Provisional; Region: PRK09929
585397001049	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
585397001050	Propionate catabolism activator; Region: PrpR_N; pfam06506
585397001051	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397001052	Walker A motif; other site
585397001053	ATP binding site [chemical binding]; other site
585397001054	Walker B motif; other site
585397001055	arginine finger; other site
585397001056	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
585397001057	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
585397001058	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
585397001059	tetramer interface [polypeptide binding]; other site
585397001060	active site
585397001061	Mg2+/Mn2+ binding site [ion binding]; other site
585397001062	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
585397001063	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
585397001064	dimer interface [polypeptide binding]; other site
585397001065	active site
585397001066	citrylCoA binding site [chemical binding]; other site
585397001067	oxalacetate/citrate binding site [chemical binding]; other site
585397001068	coenzyme A binding site [chemical binding]; other site
585397001069	catalytic triad [active]
585397001070	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
585397001071	2-methylcitrate dehydratase; Region: prpD; TIGR02330
585397001072	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
585397001073	Propionyl-CoA synthetase (PrpE); Region: PrpE; cd05967
585397001074	acyl-activating enzyme (AAE) consensus motif; other site
585397001075	putative AMP binding site [chemical binding]; other site
585397001076	putative active site [active]
585397001077	putative CoA binding site [chemical binding]; other site
585397001078	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
585397001079	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
585397001080	Na binding site [ion binding]; other site
585397001081	putative substrate binding site [chemical binding]; other site
585397001082	cytosine deaminase; Provisional; Region: PRK09230
585397001083	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
585397001084	active site
585397001085	galactoside O-acetyltransferase; Reviewed; Region: lacA; PRK09527
585397001086	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
585397001087	active site
585397001088	substrate binding site [chemical binding]; other site
585397001089	trimer interface [polypeptide binding]; other site
585397001090	CoA binding site [chemical binding]; other site
585397001091	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
585397001092	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397001093	putative substrate translocation pore; other site
585397001094	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
585397001095	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
585397001096	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
585397001097	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
585397001098	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
585397001099	lac repressor; Reviewed; Region: lacI; PRK09526
585397001100	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585397001101	DNA binding site [nucleotide binding]
585397001102	domain linker motif; other site
585397001103	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
585397001104	ligand binding site [chemical binding]; other site
585397001105	dimerization interface (open form) [polypeptide binding]; other site
585397001106	dimerization interface (closed form) [polypeptide binding]; other site
585397001107	DNA-binding transcriptional activator MhpR; Provisional; Region: PRK09834
585397001108	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
585397001109	Bacterial transcriptional regulator; Region: IclR; pfam01614
585397001110	3-(3-hydroxyphenyl)propionate hydroxylase; Validated; Region: mhpA; PRK06183
585397001111	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
585397001112	Subunit B of the Class III Extradiol ring-cleavage dioxygenase, 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB), which catalyzes the oxidization and subsequent ring-opening of 2,3-dihydroxyphenylpropionate; Region: MhpB_like; cd07365
585397001113	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
585397001114	putative active site [active]
585397001115	Fe(II) binding site [ion binding]; other site
585397001116	putative dimer interface [polypeptide binding]; other site
585397001117	putative tetramer interface [polypeptide binding]; other site
585397001118	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; Region: biphenyl_bphD; TIGR03343
585397001119	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
585397001120	nucleophilic elbow; other site
585397001121	catalytic triad; other site
585397001122	2-keto-4-pentenoate hydratase; Provisional; Region: mhpD; PRK11342
585397001123	acetaldehyde dehydrogenase; Validated; Region: PRK08300
585397001124	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
585397001125	Prokaryotic acetaldehyde dehydrogenase, dimerisation; Region: AcetDehyd-dimer; pfam09290
585397001126	4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated; Region: PRK08195
585397001127	4-hydroxy-2-oxovalerate aldolase, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_HOA; cd07943
585397001128	active site
585397001129	catalytic residues [active]
585397001130	metal binding site [ion binding]; metal-binding site
585397001131	DmpG-like communication domain; Region: DmpG_comm; pfam07836
585397001132	putative 3-hydroxyphenylpropionic transporter MhpT; Provisional; Region: PRK11551
585397001133	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397001134	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397001135	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
585397001136	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
585397001137	S-formylglutathione hydrolase; Region: PLN02442
585397001138	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
585397001139	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
585397001140	substrate binding site [chemical binding]; other site
585397001141	catalytic Zn binding site [ion binding]; other site
585397001142	NAD binding site [chemical binding]; other site
585397001143	structural Zn binding site [ion binding]; other site
585397001144	dimer interface [polypeptide binding]; other site
585397001145	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
585397001146	putative metal binding site [ion binding]; other site
585397001147	putative homodimer interface [polypeptide binding]; other site
585397001148	putative homotetramer interface [polypeptide binding]; other site
585397001149	putative homodimer-homodimer interface [polypeptide binding]; other site
585397001150	putative allosteric switch controlling residues; other site
585397001151	fragment of conserved hypothetical protein (part 2);Evidence 7 : Gene remnant
585397001152	fragment of conserved hypothetical protein (part 1);Evidence 7 : Gene remnant
585397001153	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
585397001154	putative trimer interface [polypeptide binding]; other site
585397001155	putative CoA binding site [chemical binding]; other site
585397001156	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
585397001157	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
585397001158	DXD motif; other site
585397001159	Uncharacterized proteins, LmbE homologs [Function unknown]; Region: COG2120
585397001160	ABC-type taurine transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: TauA; COG4521
585397001161	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585397001162	substrate binding pocket [chemical binding]; other site
585397001163	membrane-bound complex binding site; other site
585397001164	hinge residues; other site
585397001165	taurine transporter ATP-binding subunit; Provisional; Region: tauB; PRK11248
585397001166	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
585397001167	Walker A/P-loop; other site
585397001168	ATP binding site [chemical binding]; other site
585397001169	Q-loop/lid; other site
585397001170	ABC transporter signature motif; other site
585397001171	Walker B; other site
585397001172	D-loop; other site
585397001173	H-loop/switch region; other site
585397001174	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
585397001175	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397001176	dimer interface [polypeptide binding]; other site
585397001177	conserved gate region; other site
585397001178	putative PBP binding loops; other site
585397001179	ABC-ATPase subunit interface; other site
585397001180	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
585397001181	taurine dioxygenase; Reviewed; Region: tauD; PRK09553
585397001182	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
585397001183	dimer interface [polypeptide binding]; other site
585397001184	active site
585397001185	Schiff base residues; other site
585397001186	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397001187	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397001188	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397001189	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397001190	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
585397001191	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
585397001192	microcin B17 transporter; Reviewed; Region: PRK11098
585397001193	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
585397001194	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
585397001195	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
585397001196	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
585397001197	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
585397001198	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
585397001199	anti-RssB factor; Provisional; Region: PRK10244
585397001200	alkaline phosphatase; Provisional; Region: PRK10518
585397001201	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
585397001202	dimer interface [polypeptide binding]; other site
585397001203	active site
585397001204	hypothetical protein; Provisional; Region: PRK11505
585397001205	psiF repeat; Region: PsiF_repeat; pfam07769
585397001206	psiF repeat; Region: PsiF_repeat; pfam07769
585397001207	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
585397001208	MASE2 domain; Region: MASE2; pfam05230
585397001209	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585397001210	metal binding site [ion binding]; metal-binding site
585397001211	active site
585397001212	I-site; other site
585397001213	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
585397001214	pyrroline-5-carboxylate reductase; Region: PLN02688
585397001215	hypothetical protein; Validated; Region: PRK00124
585397001216	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
585397001217	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
585397001218	ADP binding site [chemical binding]; other site
585397001219	magnesium binding site [ion binding]; other site
585397001220	putative shikimate binding site; other site
585397001221	hypothetical protein; Provisional; Region: PRK10380
585397001222	hypothetical protein; Provisional; Region: PRK10481
585397001223	hypothetical protein; Provisional; Region: PRK10579
585397001224	Protein of unknown function (DUF2773); Region: DUF2773; pfam10971
585397001225	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
585397001226	fructokinase; Reviewed; Region: PRK09557
585397001227	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
585397001228	nucleotide binding site [chemical binding]; other site
585397001229	MFS transport protein AraJ; Provisional; Region: PRK10091
585397001230	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397001231	putative substrate translocation pore; other site
585397001232	exonuclease subunit SbcC; Provisional; Region: PRK10246
585397001233	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397001234	Walker A/P-loop; other site
585397001235	ATP binding site [chemical binding]; other site
585397001236	Q-loop/lid; other site
585397001237	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397001238	ABC transporter signature motif; other site
585397001239	Walker B; other site
585397001240	D-loop; other site
585397001241	H-loop/switch region; other site
585397001242	exonuclease subunit SbcD; Provisional; Region: PRK10966
585397001243	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
585397001244	active site
585397001245	metal binding site [ion binding]; metal-binding site
585397001246	DNA binding site [nucleotide binding]
585397001247	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
585397001248	transcriptional regulator PhoB; Provisional; Region: PRK10161
585397001249	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397001250	active site
585397001251	phosphorylation site [posttranslational modification]
585397001252	intermolecular recognition site; other site
585397001253	dimerization interface [polypeptide binding]; other site
585397001254	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585397001255	DNA binding site [nucleotide binding]
585397001256	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
585397001257	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
585397001258	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585397001259	putative active site [active]
585397001260	heme pocket [chemical binding]; other site
585397001261	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585397001262	dimer interface [polypeptide binding]; other site
585397001263	phosphorylation site [posttranslational modification]
585397001264	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397001265	ATP binding site [chemical binding]; other site
585397001266	Mg2+ binding site [ion binding]; other site
585397001267	G-X-G motif; other site
585397001268	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
585397001269	putative proline-specific permease; Provisional; Region: proY; PRK10580
585397001270	Spore germination protein; Region: Spore_permease; cl17796
585397001271	maltodextrin glucosidase; Provisional; Region: PRK10785
585397001272	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
585397001273	homodimer interface [polypeptide binding]; other site
585397001274	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
585397001275	active site
585397001276	homodimer interface [polypeptide binding]; other site
585397001277	catalytic site [active]
585397001278	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
585397001279	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
585397001280	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
585397001281	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
585397001282	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
585397001283	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
585397001284	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
585397001285	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
585397001286	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
585397001287	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
585397001288	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
585397001289	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
585397001290	Protein export membrane protein; Region: SecD_SecF; pfam02355
585397001291	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
585397001292	active site
585397001293	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
585397001294	hypothetical protein; Provisional; Region: PRK11530
585397001295	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
585397001296	ATP cone domain; Region: ATP-cone; pfam03477
585397001297	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
585397001298	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
585397001299	catalytic motif [active]
585397001300	Zn binding site [ion binding]; other site
585397001301	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
585397001302	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
585397001303	homopentamer interface [polypeptide binding]; other site
585397001304	active site
585397001305	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
585397001306	putative RNA binding site [nucleotide binding]; other site
585397001307	thiamine monophosphate kinase; Provisional; Region: PRK05731
585397001308	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
585397001309	ATP binding site [chemical binding]; other site
585397001310	dimerization interface [polypeptide binding]; other site
585397001311	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
585397001312	tetramer interfaces [polypeptide binding]; other site
585397001313	binuclear metal-binding site [ion binding]; other site
585397001314	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
585397001315	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
585397001316	active site
585397001317	catalytic tetrad [active]
585397001318	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
585397001319	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
585397001320	TPP-binding site; other site
585397001321	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
585397001322	PYR/PP interface [polypeptide binding]; other site
585397001323	dimer interface [polypeptide binding]; other site
585397001324	TPP binding site [chemical binding]; other site
585397001325	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
585397001326	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
585397001327	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
585397001328	substrate binding pocket [chemical binding]; other site
585397001329	chain length determination region; other site
585397001330	substrate-Mg2+ binding site; other site
585397001331	catalytic residues [active]
585397001332	aspartate-rich region 1; other site
585397001333	active site lid residues [active]
585397001334	aspartate-rich region 2; other site
585397001335	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
585397001336	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
585397001337	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
585397001338	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
585397001339	Ligand Binding Site [chemical binding]; other site
585397001340	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
585397001341	active site residue [active]
585397001342	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
585397001343	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
585397001344	conserved cys residue [active]
585397001345	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
585397001346	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
585397001347	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
585397001348	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
585397001349	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
585397001350	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397001351	Major Facilitator Superfamily; Region: MFS_1; pfam07690
585397001352	putative substrate translocation pore; other site
585397001353	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
585397001354	UbiA prenyltransferase family; Region: UbiA; pfam01040
585397001355	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
585397001356	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
585397001357	Subunit I/III interface [polypeptide binding]; other site
585397001358	Subunit III/IV interface [polypeptide binding]; other site
585397001359	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
585397001360	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
585397001361	D-pathway; other site
585397001362	Putative ubiquinol binding site [chemical binding]; other site
585397001363	Low-spin heme (heme b) binding site [chemical binding]; other site
585397001364	Putative water exit pathway; other site
585397001365	Binuclear center (heme o3/CuB) [ion binding]; other site
585397001366	K-pathway; other site
585397001367	Putative proton exit pathway; other site
585397001368	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
585397001369	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
585397001370	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
585397001371	muropeptide transporter; Reviewed; Region: ampG; PRK11902
585397001372	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397001373	putative substrate translocation pore; other site
585397001374	hypothetical protein; Provisional; Region: PRK11627
585397001375	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
585397001376	transcriptional regulator BolA; Provisional; Region: PRK11628
585397001377	trigger factor; Provisional; Region: tig; PRK01490
585397001378	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
585397001379	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
585397001380	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
585397001381	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
585397001382	oligomer interface [polypeptide binding]; other site
585397001383	active site residues [active]
585397001384	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
585397001385	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
585397001386	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397001387	Walker A motif; other site
585397001388	ATP binding site [chemical binding]; other site
585397001389	Walker B motif; other site
585397001390	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
585397001391	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
585397001392	Found in ATP-dependent protease La (LON); Region: LON; smart00464
585397001393	Found in ATP-dependent protease La (LON); Region: LON; smart00464
585397001394	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397001395	Walker A motif; other site
585397001396	ATP binding site [chemical binding]; other site
585397001397	Walker B motif; other site
585397001398	arginine finger; other site
585397001399	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
585397001400	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
585397001401	IHF dimer interface [polypeptide binding]; other site
585397001402	IHF - DNA interface [nucleotide binding]; other site
585397001403	periplasmic folding chaperone; Provisional; Region: PRK10788
585397001404	SurA N-terminal domain; Region: SurA_N_3; cl07813
585397001405	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
585397001406	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
585397001407	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
585397001408	active site
585397001409	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
585397001410	Ligand Binding Site [chemical binding]; other site
585397001411	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
585397001412	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
585397001413	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
585397001414	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
585397001415	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397001416	active site
585397001417	motif I; other site
585397001418	motif II; other site
585397001419	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
585397001420	dimerization interface [polypeptide binding]; other site
585397001421	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
585397001422	putative DNA binding site [nucleotide binding]; other site
585397001423	putative Zn2+ binding site [ion binding]; other site
585397001424	AsnC family; Region: AsnC_trans_reg; pfam01037
585397001425	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
585397001426	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
585397001427	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397001428	Walker A/P-loop; other site
585397001429	ATP binding site [chemical binding]; other site
585397001430	Q-loop/lid; other site
585397001431	ABC transporter signature motif; other site
585397001432	Walker B; other site
585397001433	D-loop; other site
585397001434	H-loop/switch region; other site
585397001435	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
585397001436	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
585397001437	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
585397001438	Walker A/P-loop; other site
585397001439	ATP binding site [chemical binding]; other site
585397001440	Q-loop/lid; other site
585397001441	ABC transporter signature motif; other site
585397001442	Walker B; other site
585397001443	D-loop; other site
585397001444	H-loop/switch region; other site
585397001445	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
585397001446	Nitrogen regulatory protein P-II; Region: P-II; smart00938
585397001447	ammonium transporter; Provisional; Region: PRK10666
585397001448	acyl-CoA thioesterase II; Provisional; Region: PRK10526
585397001449	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
585397001450	active site
585397001451	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
585397001452	catalytic triad [active]
585397001453	dimer interface [polypeptide binding]; other site
585397001454	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
585397001455	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
585397001456	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
585397001457	DNA binding site [nucleotide binding]
585397001458	active site
585397001459	Uncharacterized conserved protein [Function unknown]; Region: COG5507
585397001460	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
585397001461	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
585397001462	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585397001463	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
585397001464	maltose O-acetyltransferase; Provisional; Region: PRK10092
585397001465	Maltose acetyltransferase; Region: Mac; pfam12464
585397001466	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
585397001467	trimer interface [polypeptide binding]; other site
585397001468	active site
585397001469	substrate binding site [chemical binding]; other site
585397001470	CoA binding site [chemical binding]; other site
585397001471	gene expression modulator; Provisional; Region: PRK10945
585397001472	Biofilm formation regulator YbaJ; Region: YbaJ; pfam10757
585397001473	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
585397001474	Protein export membrane protein; Region: SecD_SecF; cl14618
585397001475	Protein export membrane protein; Region: SecD_SecF; cl14618
585397001476	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
585397001477	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585397001478	HlyD family secretion protein; Region: HlyD_3; pfam13437
585397001479	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
585397001480	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585397001481	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
585397001482	hypothetical protein; Provisional; Region: PRK11281
585397001483	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
585397001484	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
585397001485	Mechanosensitive ion channel; Region: MS_channel; pfam00924
585397001486	hypothetical protein; Provisional; Region: PRK11038
585397001487	primosomal replication protein N''; Provisional; Region: PRK10093
585397001488	hypothetical protein; Provisional; Region: PRK10527
585397001489	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
585397001490	active site
585397001491	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
585397001492	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397001493	Walker A motif; other site
585397001494	ATP binding site [chemical binding]; other site
585397001495	Walker B motif; other site
585397001496	DNA polymerase III subunit delta'; Validated; Region: PRK08485
585397001497	arginine finger; other site
585397001498	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
585397001499	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
585397001500	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
585397001501	hypothetical protein; Validated; Region: PRK00153
585397001502	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecR; COG0353
585397001503	RecR protein; Region: RecR; pfam02132
585397001504	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
585397001505	putative active site [active]
585397001506	putative metal-binding site [ion binding]; other site
585397001507	tetramer interface [polypeptide binding]; other site
585397001508	heat shock protein 90; Provisional; Region: PRK05218
585397001509	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397001510	ATP binding site [chemical binding]; other site
585397001511	Mg2+ binding site [ion binding]; other site
585397001512	G-X-G motif; other site
585397001513	adenylate kinase; Reviewed; Region: adk; PRK00279
585397001514	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
585397001515	AMP-binding site [chemical binding]; other site
585397001516	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
585397001517	ferrochelatase; Region: hemH; TIGR00109
585397001518	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
585397001519	C-terminal domain interface [polypeptide binding]; other site
585397001520	active site
585397001521	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
585397001522	active site
585397001523	N-terminal domain interface [polypeptide binding]; other site
585397001524	acetyl esterase; Provisional; Region: PRK10162
585397001525	inosine/guanosine kinase; Provisional; Region: PRK15074
585397001526	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
585397001527	putative cation:proton antiport protein; Provisional; Region: PRK10669
585397001528	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
585397001529	TrkA-N domain; Region: TrkA_N; pfam02254
585397001530	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397001531	Major Facilitator Superfamily; Region: MFS_1; pfam07690
585397001532	putative substrate translocation pore; other site
585397001533	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
585397001534	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
585397001535	active site
585397001536	metal binding site [ion binding]; metal-binding site
585397001537	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
585397001538	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
585397001539	putative deacylase active site [active]
585397001540	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
585397001541	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
585397001542	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
585397001543	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397001544	non-specific DNA binding site [nucleotide binding]; other site
585397001545	salt bridge; other site
585397001546	sequence-specific DNA binding site [nucleotide binding]; other site
585397001547	copper exporting ATPase; Provisional; Region: copA; PRK10671
585397001548	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
585397001549	metal-binding site [ion binding]
585397001550	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
585397001551	metal-binding site [ion binding]
585397001552	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
585397001553	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397001554	motif II; other site
585397001555	glutaminase; Reviewed; Region: PRK12356
585397001556	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
585397001557	amino acid transporter; Region: 2A0306; TIGR00909
585397001558	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
585397001559	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
585397001560	DNA binding residues [nucleotide binding]
585397001561	dimer interface [polypeptide binding]; other site
585397001562	copper binding site [ion binding]; other site
585397001563	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
585397001564	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
585397001565	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
585397001566	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
585397001567	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397001568	Walker A/P-loop; other site
585397001569	ATP binding site [chemical binding]; other site
585397001570	Q-loop/lid; other site
585397001571	ABC transporter signature motif; other site
585397001572	Walker B; other site
585397001573	D-loop; other site
585397001574	H-loop/switch region; other site
585397001575	Uncharacterized protein family (UPF0014); Region: UPF0014; pfam03649
585397001576	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
585397001577	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
585397001578	oxidoreductase; Provisional; Region: PRK08017
585397001579	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
585397001580	NADP binding site [chemical binding]; other site
585397001581	active site
585397001582	steroid binding site; other site
585397001583	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
585397001584	active site
585397001585	catalytic triad [active]
585397001586	oxyanion hole [active]
585397001587	switch loop; other site
585397001588	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
585397001589	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
585397001590	Walker A/P-loop; other site
585397001591	ATP binding site [chemical binding]; other site
585397001592	Q-loop/lid; other site
585397001593	ABC transporter signature motif; other site
585397001594	Walker B; other site
585397001595	D-loop; other site
585397001596	H-loop/switch region; other site
585397001597	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
585397001598	FtsX-like permease family; Region: FtsX; pfam02687
585397001599	FtsX-like permease family; Region: FtsX; pfam02687
585397001600	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
585397001601	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
585397001602	active site residue [active]
585397001603	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
585397001604	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397001605	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
585397001606	dimerization interface [polypeptide binding]; other site
585397001607	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
585397001608	ureidoglycolate hydrolase; Provisional; Region: PRK03606
585397001609	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
585397001610	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
585397001611	Bacterial transcriptional regulator; Region: IclR; pfam01614
585397001612	glyoxylate carboligase; Provisional; Region: PRK11269
585397001613	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
585397001614	PYR/PP interface [polypeptide binding]; other site
585397001615	dimer interface [polypeptide binding]; other site
585397001616	TPP binding site [chemical binding]; other site
585397001617	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
585397001618	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
585397001619	TPP-binding site [chemical binding]; other site
585397001620	tartronate semialdehyde reductase; Provisional; Region: PRK15059
585397001621	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
585397001622	nucleobase-cation-symport-1 (NCS1) transporters; solute-binding domain; Region: SLC-NCS1sbd; cd10323
585397001623	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
585397001624	Na binding site [ion binding]; other site
585397001625	substrate binding site [chemical binding]; other site
585397001626	allantoinase; Provisional; Region: PRK08044
585397001627	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
585397001628	active site
585397001629	putative uracil/xanthine transporter; Provisional; Region: PRK11412
585397001630	glycerate kinase II; Provisional; Region: PRK09932
585397001631	putative allantoin catabolism protein; Region: ura-cupin; TIGR03214
585397001632	Protein of unknown function (DUF861); Region: Cupin_3; pfam05899
585397001633	Cupin domain; Region: Cupin_2; cl17218
585397001634	allantoate amidohydrolase; Region: AllC; TIGR03176
585397001635	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
585397001636	active site
585397001637	metal binding site [ion binding]; metal-binding site
585397001638	dimer interface [polypeptide binding]; other site
585397001639	ureidoglycolate dehydrogenase; Provisional; Region: PRK15025
585397001640	membrane protein FdrA; Validated; Region: PRK06091
585397001641	CoA binding domain; Region: CoA_binding; pfam02629
585397001642	CoA-ligase; Region: Ligase_CoA; pfam00549
585397001643	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
585397001644	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
585397001645	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
585397001646	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
585397001647	putative substrate binding site [chemical binding]; other site
585397001648	nucleotide binding site [chemical binding]; other site
585397001649	nucleotide binding site [chemical binding]; other site
585397001650	homodimer interface [polypeptide binding]; other site
585397001651	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
585397001652	ATP-grasp domain; Region: ATP-grasp; pfam02222
585397001653	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
585397001654	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
585397001655	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
585397001656	putative active site [active]
585397001657	putative metal binding site [ion binding]; other site
585397001658	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
585397001659	substrate binding site [chemical binding]; other site
585397001660	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
585397001661	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
585397001662	active site
585397001663	HIGH motif; other site
585397001664	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
585397001665	KMSKS motif; other site
585397001666	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
585397001667	tRNA binding surface [nucleotide binding]; other site
585397001668	anticodon binding site; other site
585397001669	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
585397001670	ribosome-associated protein; Provisional; Region: PRK11507
585397001671	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
585397001672	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
585397001673	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
585397001674	homodimer interface [polypeptide binding]; other site
585397001675	NADP binding site [chemical binding]; other site
585397001676	substrate binding site [chemical binding]; other site
585397001677	fragment of putative integrase; DLP12 prophage (part 2);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397001678	fragment of putative integrase; DLP12 prophage (part 1);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397001679	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
585397001680	Methyltransferase domain; Region: Methyltransf_23; pfam13489
585397001681	Methyltransferase domain; Region: Methyltransf_12; pfam08242
585397001682	S-adenosylmethionine binding site [chemical binding]; other site
585397001683	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397001684	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397001685	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397001686	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397001687	fragment of outer membrane protease VII (outer membrane protein 3b); DLP12 prophage (partial);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585397001688	hypothetical protein; Provisional; Region: PRK09936
585397001689	bacteriophage N4 receptor, outer membrane subunit; Provisional; Region: PRK09782
585397001690	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585397001691	TPR motif; other site
585397001692	binding surface
585397001693	Bacteriophage N adsorption protein A C-term; Region: NfrA_C; pfam13283
585397001694	fragment of bacteriophage N4 receptor, inner membrane subunit (part 2);Evidence 7 : Gene remnant; Product type m : membrane component
585397001695	fragment of bacteriophage N4 receptor, inner membrane subunit (part 1);Evidence 7 : Gene remnant; Product type m : membrane component
585397001696	sensor kinase CusS; Provisional; Region: PRK09835
585397001697	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585397001698	dimerization interface [polypeptide binding]; other site
585397001699	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585397001700	dimer interface [polypeptide binding]; other site
585397001701	phosphorylation site [posttranslational modification]
585397001702	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397001703	ATP binding site [chemical binding]; other site
585397001704	Mg2+ binding site [ion binding]; other site
585397001705	G-X-G motif; other site
585397001706	DNA-binding transcriptional activator CusR; Provisional; Region: PRK09836
585397001707	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397001708	active site
585397001709	phosphorylation site [posttranslational modification]
585397001710	intermolecular recognition site; other site
585397001711	dimerization interface [polypeptide binding]; other site
585397001712	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585397001713	DNA binding site [nucleotide binding]
585397001714	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
585397001715	periplasmic copper-binding protein; Provisional; Region: PRK09838
585397001716	copper/silver efflux system membrane fusion protein CusB; Provisional; Region: PRK09783
585397001717	HlyD family secretion protein; Region: HlyD_3; pfam13437
585397001718	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
585397001719	phenylalanine transporter; Provisional; Region: PRK10249
585397001720	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
585397001721	Mechanosensitive ion channel; Region: MS_channel; pfam00924
585397001722	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
585397001723	dimer interface [polypeptide binding]; other site
585397001724	FMN binding site [chemical binding]; other site
585397001725	hypothetical protein; Provisional; Region: PRK10250
585397001726	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
585397001727	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
585397001728	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
585397001729	Hok/gef family; Region: HOK_GEF; pfam01848
585397001730	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
585397001731	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
585397001732	fragment of iron-enterobactin outer membrane transporter (part 2);Evidence 7 : Gene remnant; Product type t : transporter
585397001733	fragment of iron-enterobactin outer membrane transporter (part 1);Evidence 7 : Gene remnant; Product type t : transporter
585397001734	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
585397001735	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
585397001736	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
585397001737	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
585397001738	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
585397001739	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
585397001740	acyl-activating enzyme (AAE) consensus motif; other site
585397001741	AMP binding site [chemical binding]; other site
585397001742	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
585397001743	regulator of length of O-antigen component of lipopolysaccharide chains (part 1);Evidence 2b : Function of strongly homologous gene; Product type r : regulator
585397001744	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
585397001745	Chain length determinant protein; Region: Wzz; pfam02706
585397001746	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
585397001747	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
585397001748	Walker A/P-loop; other site
585397001749	ATP binding site [chemical binding]; other site
585397001750	Q-loop/lid; other site
585397001751	ABC transporter signature motif; other site
585397001752	Walker B; other site
585397001753	D-loop; other site
585397001754	H-loop/switch region; other site
585397001755	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
585397001756	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
585397001757	ABC-ATPase subunit  interface; other site
585397001758	dimer interface [polypeptide binding]; other site
585397001759	putative PBP binding regions; other site
585397001760	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
585397001761	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
585397001762	ABC-ATPase subunit  interface; other site
585397001763	dimer interface [polypeptide binding]; other site
585397001764	putative PBP binding regions; other site
585397001765	enterobactin exporter EntS; Provisional; Region: PRK10489
585397001766	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397001767	putative substrate translocation pore; other site
585397001768	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
585397001769	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
585397001770	siderophore binding site; other site
585397001771	isochorismate synthase EntC; Provisional; Region: PRK15016
585397001772	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
585397001773	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
585397001774	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
585397001775	acyl-activating enzyme (AAE) consensus motif; other site
585397001776	active site
585397001777	AMP binding site [chemical binding]; other site
585397001778	substrate binding site [chemical binding]; other site
585397001779	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
585397001780	hydrophobic substrate binding pocket; other site
585397001781	Isochorismatase family; Region: Isochorismatase; pfam00857
585397001782	active site
585397001783	conserved cis-peptide bond; other site
585397001784	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
585397001785	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
585397001786	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
585397001787	putative NAD(P) binding site [chemical binding]; other site
585397001788	active site
585397001789	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
585397001790	CoenzymeA binding site [chemical binding]; other site
585397001791	subunit interaction site [polypeptide binding]; other site
585397001792	PHB binding site; other site
585397001793	fragment of carbon starvation protein (part 1);Evidence 7 : Gene remnant; Product type pf : putative factor
585397001794	fragment of carbon starvation protein (part 2);Evidence 7 : Gene remnant; Product type pf : putative factor
585397001795	Uncharacterized small protein [Function unknown]; Region: COG2879
585397001796	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
585397001797	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
585397001798	putative active site [active]
585397001799	metal binding site [ion binding]; metal-binding site
585397001800	methionine aminotransferase; Validated; Region: PRK09082
585397001801	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585397001802	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397001803	homodimer interface [polypeptide binding]; other site
585397001804	catalytic residue [active]
585397001805	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
585397001806	ParB-like nuclease domain; Region: ParBc; pfam02195
585397001807	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
585397001808	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
585397001809	Active Sites [active]
585397001810	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
585397001811	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
585397001812	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397001813	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
585397001814	dimerization interface [polypeptide binding]; other site
585397001815	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
585397001816	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
585397001817	dimerization domain [polypeptide binding]; other site
585397001818	dimer interface [polypeptide binding]; other site
585397001819	catalytic residues [active]
585397001820	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
585397001821	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
585397001822	dimer interface [polypeptide binding]; other site
585397001823	decamer (pentamer of dimers) interface [polypeptide binding]; other site
585397001824	catalytic triad [active]
585397001825	peroxidatic and resolving cysteines [active]
585397001826	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
585397001827	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
585397001828	catalytic residue [active]
585397001829	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
585397001830	catalytic residues [active]
585397001831	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
585397001832	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585397001833	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
585397001834	Ligand Binding Site [chemical binding]; other site
585397001835	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
585397001836	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
585397001837	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
585397001838	B1 nucleotide binding pocket [chemical binding]; other site
585397001839	B2 nucleotide binding pocket [chemical binding]; other site
585397001840	CAS motifs; other site
585397001841	active site
585397001842	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
585397001843	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
585397001844	transmembrane helices; other site
585397001845	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
585397001846	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
585397001847	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
585397001848	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
585397001849	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
585397001850	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
585397001851	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
585397001852	putative active site [active]
585397001853	(T/H)XGH motif; other site
585397001854	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
585397001855	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585397001856	putative active site [active]
585397001857	heme pocket [chemical binding]; other site
585397001858	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397001859	ATP binding site [chemical binding]; other site
585397001860	Mg2+ binding site [ion binding]; other site
585397001861	G-X-G motif; other site
585397001862	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
585397001863	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397001864	active site
585397001865	phosphorylation site [posttranslational modification]
585397001866	intermolecular recognition site; other site
585397001867	dimerization interface [polypeptide binding]; other site
585397001868	Transcriptional regulator; Region: CitT; pfam12431
585397001869	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
585397001870	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
585397001871	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
585397001872	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
585397001873	DNA-binding site [nucleotide binding]; DNA binding site
585397001874	RNA-binding motif; other site
585397001875	chromosome condensation membrane protein; Provisional; Region: PRK14196
585397001876	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
585397001877	Predicted amidohydrolase [General function prediction only]; Region: COG0388
585397001878	active site
585397001879	catalytic triad [active]
585397001880	dimer interface [polypeptide binding]; other site
585397001881	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
585397001882	lipoyl synthase; Provisional; Region: PRK05481
585397001883	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585397001884	FeS/SAM binding site; other site
585397001885	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
585397001886	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
585397001887	lipoate-protein ligase B; Provisional; Region: PRK14342
585397001888	hypothetical protein; Provisional; Region: PRK04998
585397001889	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
585397001890	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
585397001891	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
585397001892	rare lipoprotein A; Provisional; Region: PRK10672
585397001893	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
585397001894	Sporulation related domain; Region: SPOR; pfam05036
585397001895	cell wall shape-determining protein; Provisional; Region: PRK10794
585397001896	penicillin-binding protein 2; Provisional; Region: PRK10795
585397001897	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
585397001898	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
585397001899	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
585397001900	ribosome-associated protein; Provisional; Region: PRK11538
585397001901	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
585397001902	catalytic core [active]
585397001903	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
585397001904	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
585397001905	active site
585397001906	(T/H)XGH motif; other site
585397001907	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
585397001908	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
585397001909	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
585397001910	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
585397001911	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
585397001912	HIGH motif; other site
585397001913	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
585397001914	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
585397001915	active site
585397001916	KMSKS motif; other site
585397001917	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
585397001918	tRNA binding surface [nucleotide binding]; other site
585397001919	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
585397001920	hypothetical protein; Provisional; Region: PRK11032
585397001921	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
585397001922	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
585397001923	active site
585397001924	tetramer interface [polypeptide binding]; other site
585397001925	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
585397001926	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
585397001927	Walker A/P-loop; other site
585397001928	ATP binding site [chemical binding]; other site
585397001929	Q-loop/lid; other site
585397001930	ABC transporter signature motif; other site
585397001931	Walker B; other site
585397001932	D-loop; other site
585397001933	H-loop/switch region; other site
585397001934	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
585397001935	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397001936	dimer interface [polypeptide binding]; other site
585397001937	conserved gate region; other site
585397001938	putative PBP binding loops; other site
585397001939	ABC-ATPase subunit interface; other site
585397001940	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
585397001941	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397001942	dimer interface [polypeptide binding]; other site
585397001943	conserved gate region; other site
585397001944	putative PBP binding loops; other site
585397001945	ABC-ATPase subunit interface; other site
585397001946	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
585397001947	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585397001948	substrate binding pocket [chemical binding]; other site
585397001949	membrane-bound complex binding site; other site
585397001950	hinge residues; other site
585397001951	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
585397001952	Uncharacterized conserved protein [Function unknown]; Region: COG3391
585397001953	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
585397001954	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
585397001955	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
585397001956	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
585397001957	putative active site [active]
585397001958	catalytic triad [active]
585397001959	putative dimer interface [polypeptide binding]; other site
585397001960	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
585397001961	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
585397001962	Transporter associated domain; Region: CorC_HlyC; smart01091
585397001963	metal-binding heat shock protein; Provisional; Region: PRK00016
585397001964	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
585397001965	PhoH-like protein; Region: PhoH; pfam02562
585397001966	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
585397001967	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
585397001968	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585397001969	FeS/SAM binding site; other site
585397001970	TRAM domain; Region: TRAM; pfam01938
585397001971	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
585397001972	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
585397001973	asparagine synthetase B; Provisional; Region: asnB; PRK09431
585397001974	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
585397001975	active site
585397001976	dimer interface [polypeptide binding]; other site
585397001977	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
585397001978	Ligand Binding Site [chemical binding]; other site
585397001979	Molecular Tunnel; other site
585397001980	UMP phosphatase; Provisional; Region: PRK10444
585397001981	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397001982	active site
585397001983	motif I; other site
585397001984	motif II; other site
585397001985	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397001986	MarR family; Region: MarR; pfam01047
585397001987	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
585397001988	ROK family; Region: ROK; pfam00480
585397001989	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
585397001990	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
585397001991	active site
585397001992	dimer interface [polypeptide binding]; other site
585397001993	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
585397001994	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
585397001995	active site
585397001996	trimer interface [polypeptide binding]; other site
585397001997	allosteric site; other site
585397001998	active site lid [active]
585397001999	hexamer (dimer of trimers) interface [polypeptide binding]; other site
585397002000	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
585397002001	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
585397002002	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
585397002003	active site turn [active]
585397002004	phosphorylation site [posttranslational modification]
585397002005	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
585397002006	HPr interaction site; other site
585397002007	glycerol kinase (GK) interaction site [polypeptide binding]; other site
585397002008	active site
585397002009	phosphorylation site [posttranslational modification]
585397002010	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
585397002011	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
585397002012	active site
585397002013	HIGH motif; other site
585397002014	nucleotide binding site [chemical binding]; other site
585397002015	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
585397002016	KMSKS motif; other site
585397002017	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
585397002018	outer membrane porin, OprD family; Region: OprD; pfam03573
585397002019	YbfN-like lipoprotein; Region: YbfN; pfam13982
585397002020	ferric uptake regulator; Provisional; Region: fur; PRK09462
585397002021	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
585397002022	metal binding site 2 [ion binding]; metal-binding site
585397002023	putative DNA binding helix; other site
585397002024	metal binding site 1 [ion binding]; metal-binding site
585397002025	dimer interface [polypeptide binding]; other site
585397002026	structural Zn2+ binding site [ion binding]; other site
585397002027	flavodoxin FldA; Validated; Region: PRK09267
585397002028	LexA regulated protein; Provisional; Region: PRK11675
585397002029	acyl-CoA esterase; Provisional; Region: PRK10673
585397002030	PGAP1-like protein; Region: PGAP1; pfam07819
585397002031	replication initiation regulator SeqA; Provisional; Region: PRK11187
585397002032	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
585397002033	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
585397002034	active site
585397002035	substrate binding site [chemical binding]; other site
585397002036	metal binding site [ion binding]; metal-binding site
585397002037	putrescine transporter; Provisional; Region: potE; PRK10655
585397002038	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
585397002039	ornithine decarboxylase; Provisional; Region: PRK13578
585397002040	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
585397002041	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
585397002042	homodimer interface [polypeptide binding]; other site
585397002043	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397002044	catalytic residue [active]
585397002045	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
585397002046	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
585397002047	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397002048	active site
585397002049	phosphorylation site [posttranslational modification]
585397002050	intermolecular recognition site; other site
585397002051	dimerization interface [polypeptide binding]; other site
585397002052	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585397002053	DNA binding site [nucleotide binding]
585397002054	sensor protein KdpD; Provisional; Region: PRK10490
585397002055	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
585397002056	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
585397002057	Ligand Binding Site [chemical binding]; other site
585397002058	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
585397002059	GAF domain; Region: GAF_3; pfam13492
585397002060	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585397002061	dimer interface [polypeptide binding]; other site
585397002062	phosphorylation site [posttranslational modification]
585397002063	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397002064	ATP binding site [chemical binding]; other site
585397002065	Mg2+ binding site [ion binding]; other site
585397002066	G-X-G motif; other site
585397002067	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
585397002068	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
585397002069	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
585397002070	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
585397002071	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
585397002072	hypothetical protein; Provisional; Region: PRK10167
585397002073	Uncharacterized conserved protein [Function unknown]; Region: COG3272
585397002074	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
585397002075	DNA photolyase; Region: DNA_photolyase; pfam00875
585397002076	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
585397002077	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397002078	putative substrate translocation pore; other site
585397002079	POT family; Region: PTR2; pfam00854
585397002080	Uncharacterized conserved protein [Function unknown]; Region: COG0327
585397002081	metal-binding protein; Provisional; Region: PRK10799
585397002082	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
585397002083	sensor histidine kinase inhibitor, KipI family; Region: TIGR00370
585397002084	biotin-dependent carboxylase uncharacterized domain; Region: urea_amlyse_rel; TIGR00724
585397002085	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
585397002086	putative active site [active]
585397002087	endonuclease VIII; Provisional; Region: PRK10445
585397002088	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
585397002089	DNA binding site [nucleotide binding]
585397002090	catalytic residue [active]
585397002091	putative catalytic residues [active]
585397002092	H2TH interface [polypeptide binding]; other site
585397002093	intercalation triad [nucleotide binding]; other site
585397002094	substrate specificity determining residue; other site
585397002095	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
585397002096	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
585397002097	Putative ammonia monooxygenase; Region: AmoA; pfam05145
585397002098	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
585397002099	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
585397002100	fragment of conserved hypothetical protein (partial);Evidence 7 : Gene remnant
585397002101	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
585397002102	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
585397002103	dimer interface [polypeptide binding]; other site
585397002104	active site
585397002105	citrylCoA binding site [chemical binding]; other site
585397002106	NADH binding [chemical binding]; other site
585397002107	cationic pore residues; other site
585397002108	oxalacetate/citrate binding site [chemical binding]; other site
585397002109	coenzyme A binding site [chemical binding]; other site
585397002110	catalytic triad [active]
585397002111	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
585397002112	Iron-sulfur protein interface; other site
585397002113	proximal quinone binding site [chemical binding]; other site
585397002114	SdhD (CybS) interface [polypeptide binding]; other site
585397002115	proximal heme binding site [chemical binding]; other site
585397002116	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
585397002117	SdhC subunit interface [polypeptide binding]; other site
585397002118	proximal heme binding site [chemical binding]; other site
585397002119	cardiolipin binding site; other site
585397002120	Iron-sulfur protein interface; other site
585397002121	proximal quinone binding site [chemical binding]; other site
585397002122	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
585397002123	L-aspartate oxidase; Provisional; Region: PRK06175
585397002124	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
585397002125	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
585397002126	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
585397002127	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
585397002128	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
585397002129	TPP-binding site [chemical binding]; other site
585397002130	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
585397002131	dimer interface [polypeptide binding]; other site
585397002132	PYR/PP interface [polypeptide binding]; other site
585397002133	TPP binding site [chemical binding]; other site
585397002134	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
585397002135	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
585397002136	E3 interaction surface; other site
585397002137	lipoyl attachment site [posttranslational modification]; other site
585397002138	e3 binding domain; Region: E3_binding; pfam02817
585397002139	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
585397002140	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
585397002141	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
585397002142	CoA-ligase; Region: Ligase_CoA; pfam00549
585397002143	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
585397002144	CoA binding domain; Region: CoA_binding; smart00881
585397002145	CoA-ligase; Region: Ligase_CoA; pfam00549
585397002146	TPR repeat; Region: TPR_11; pfam13414
585397002147	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585397002148	binding surface
585397002149	TPR motif; other site
585397002150	Tetratricopeptide repeat; Region: TPR_12; pfam13424
585397002151	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
585397002152	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
585397002153	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
585397002154	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
585397002155	hypothetical protein; Provisional; Region: PRK10588
585397002156	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
585397002157	active site
585397002158	colicin uptake protein TolQ; Provisional; Region: PRK10801
585397002159	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
585397002160	colicin uptake protein TolR; Provisional; Region: PRK11024
585397002161	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
585397002162	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
585397002163	TolA C-terminal; Region: TolA; pfam06519
585397002164	translocation protein TolB; Provisional; Region: tolB; PRK03629
585397002165	TolB amino-terminal domain; Region: TolB_N; pfam04052
585397002166	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
585397002167	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
585397002168	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
585397002169	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
585397002170	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
585397002171	ligand binding site [chemical binding]; other site
585397002172	tol-pal system protein YbgF; Provisional; Region: PRK10803
585397002173	Tetratricopeptide repeat; Region: TPR_6; pfam13174
585397002174	Tetratricopeptide repeat; Region: TPR_6; pfam13174
585397002175	quinolinate synthetase; Provisional; Region: PRK09375
585397002176	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
585397002177	zinc transporter ZitB; Provisional; Region: PRK03557
585397002178	YbgS-like protein; Region: YbgS; pfam13985
585397002179	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
585397002180	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
585397002181	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
585397002182	catalytic core [active]
585397002183	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
585397002184	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
585397002185	active site
585397002186	catalytic residues [active]
585397002187	galactokinase; Provisional; Region: PRK05101
585397002188	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
585397002189	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
585397002190	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
585397002191	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
585397002192	dimer interface [polypeptide binding]; other site
585397002193	active site
585397002194	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
585397002195	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
585397002196	NAD binding site [chemical binding]; other site
585397002197	homodimer interface [polypeptide binding]; other site
585397002198	active site
585397002199	substrate binding site [chemical binding]; other site
585397002200	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
585397002201	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
585397002202	Walker A/P-loop; other site
585397002203	ATP binding site [chemical binding]; other site
585397002204	Q-loop/lid; other site
585397002205	ABC transporter signature motif; other site
585397002206	Walker B; other site
585397002207	D-loop; other site
585397002208	H-loop/switch region; other site
585397002209	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397002210	Walker A/P-loop; other site
585397002211	ATP binding site [chemical binding]; other site
585397002212	Q-loop/lid; other site
585397002213	ABC transporter signature motif; other site
585397002214	Walker B; other site
585397002215	D-loop; other site
585397002216	H-loop/switch region; other site
585397002217	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
585397002218	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
585397002219	molybdenum-pterin binding domain; Region: Mop; TIGR00638
585397002220	TOBE domain; Region: TOBE; pfam03459
585397002221	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
585397002222	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
585397002223	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585397002224	substrate binding pocket [chemical binding]; other site
585397002225	membrane-bound complex binding site; other site
585397002226	hinge residues; other site
585397002227	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
585397002228	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397002229	dimer interface [polypeptide binding]; other site
585397002230	conserved gate region; other site
585397002231	putative PBP binding loops; other site
585397002232	ABC-ATPase subunit interface; other site
585397002233	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
585397002234	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397002235	Walker A/P-loop; other site
585397002236	ATP binding site [chemical binding]; other site
585397002237	Q-loop/lid; other site
585397002238	ABC transporter signature motif; other site
585397002239	Walker B; other site
585397002240	D-loop; other site
585397002241	H-loop/switch region; other site
585397002242	molybdenum-pterin binding domain; Region: Mop; TIGR00638
585397002243	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
585397002244	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397002245	motif II; other site
585397002246	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397002247	6-phosphogluconolactonase; Provisional; Region: PRK11028
585397002248	fragment of putative DNA-binding transcriptional regulator (part 2);Evidence 7 : Gene remnant; Product type pr : putative regulator
585397002249	fragment of putative DNA-binding transcriptional regulator (part 1);Evidence 7 : Gene remnant; Product type pr : putative regulator
585397002250	PrpF protein; Region: PrpF; pfam04303
585397002251	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
585397002252	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
585397002253	transmembrane helices; other site
585397002254	putative hydratase; Provisional; Region: PRK11413
585397002255	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
585397002256	substrate binding site [chemical binding]; other site
585397002257	ligand binding site [chemical binding]; other site
585397002258	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
585397002259	substrate binding site [chemical binding]; other site
585397002260	acyl-CoA thioesterase; Provisional; Region: PRK10531
585397002261	putative pectinesterase; Region: PLN02432; cl01911
585397002262	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
585397002263	substrate binding site [chemical binding]; other site
585397002264	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
585397002265	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
585397002266	inhibitor-cofactor binding pocket; inhibition site
585397002267	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397002268	catalytic residue [active]
585397002269	biotin synthase; Provisional; Region: PRK15108
585397002270	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585397002271	FeS/SAM binding site; other site
585397002272	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
585397002273	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
585397002274	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
585397002275	substrate-cofactor binding pocket; other site
585397002276	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397002277	catalytic residue [active]
585397002278	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
585397002279	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397002280	S-adenosylmethionine binding site [chemical binding]; other site
585397002281	AAA domain; Region: AAA_26; pfam13500
585397002282	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
585397002283	Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and...; Region: DTBS; cd03109
585397002284	ADP binding site [chemical binding]; other site
585397002285	excinuclease ABC subunit B; Provisional; Region: PRK05298
585397002286	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585397002287	ATP binding site [chemical binding]; other site
585397002288	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585397002289	nucleotide binding region [chemical binding]; other site
585397002290	ATP-binding site [chemical binding]; other site
585397002291	Ultra-violet resistance protein B; Region: UvrB; pfam12344
585397002292	UvrB/uvrC motif; Region: UVR; pfam02151
585397002293	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
585397002294	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
585397002295	putative substrate binding pocket [chemical binding]; other site
585397002296	dimer interface [polypeptide binding]; other site
585397002297	phosphate binding site [ion binding]; other site
585397002298	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
585397002299	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585397002300	FeS/SAM binding site; other site
585397002301	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
585397002302	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
585397002303	MPT binding site; other site
585397002304	trimer interface [polypeptide binding]; other site
585397002305	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
585397002306	trimer interface [polypeptide binding]; other site
585397002307	dimer interface [polypeptide binding]; other site
585397002308	putative active site [active]
585397002309	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
585397002310	MoaE interaction surface [polypeptide binding]; other site
585397002311	MoeB interaction surface [polypeptide binding]; other site
585397002312	thiocarboxylated glycine; other site
585397002313	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
585397002314	MoaE homodimer interface [polypeptide binding]; other site
585397002315	MoaD interaction [polypeptide binding]; other site
585397002316	active site residues [active]
585397002317	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
585397002318	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
585397002319	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
585397002320	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
585397002321	Predicted integral membrane protein [Function unknown]; Region: COG0392
585397002322	cardiolipin synthase 2; Provisional; Region: PRK11263
585397002323	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
585397002324	putative active site [active]
585397002325	catalytic site [active]
585397002326	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
585397002327	putative active site [active]
585397002328	catalytic site [active]
585397002329	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
585397002330	putative catalytic site [active]
585397002331	putative metal binding site [ion binding]; other site
585397002332	putative phosphate binding site [ion binding]; other site
585397002333	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
585397002334	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
585397002335	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
585397002336	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
585397002337	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
585397002338	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
585397002339	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
585397002340	Walker A/P-loop; other site
585397002341	ATP binding site [chemical binding]; other site
585397002342	Q-loop/lid; other site
585397002343	ABC transporter signature motif; other site
585397002344	Walker B; other site
585397002345	D-loop; other site
585397002346	H-loop/switch region; other site
585397002347	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
585397002348	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
585397002349	Walker A/P-loop; other site
585397002350	ATP binding site [chemical binding]; other site
585397002351	Q-loop/lid; other site
585397002352	ABC transporter signature motif; other site
585397002353	Walker B; other site
585397002354	D-loop; other site
585397002355	H-loop/switch region; other site
585397002356	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
585397002357	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585397002358	HlyD family secretion protein; Region: HlyD_3; pfam13437
585397002359	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
585397002360	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
585397002361	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
585397002362	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
585397002363	ATP binding site [chemical binding]; other site
585397002364	Mg++ binding site [ion binding]; other site
585397002365	motif III; other site
585397002366	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585397002367	nucleotide binding region [chemical binding]; other site
585397002368	ATP-binding site [chemical binding]; other site
585397002369	Domain of unknown function (DUF1768); Region: DUF1768; cl01271
585397002370	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
585397002371	DEAD_2; Region: DEAD_2; pfam06733
585397002372	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
585397002373	glycosyl transferase family protein; Provisional; Region: PRK08136
585397002374	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
585397002375	putative dehydrogenase; Provisional; Region: PRK10098
585397002376	hypothetical protein; Provisional; Region: PRK10259
585397002377	hypothetical protein; Provisional; Region: PRK11019
585397002378	Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467
585397002379	catecholate siderophore receptor Fiu; Provisional; Region: PRK09840
585397002380	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585397002381	N-terminal plug; other site
585397002382	ligand-binding site [chemical binding]; other site
585397002383	hypothetical protein; Provisional; Region: PRK10259
585397002384	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
585397002385	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
585397002386	putative mechanosensitive channel protein; Provisional; Region: PRK11465
585397002387	Mechanosensitive ion channel; Region: MS_channel; pfam00924
585397002388	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
585397002389	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
585397002390	Walker A/P-loop; other site
585397002391	ATP binding site [chemical binding]; other site
585397002392	Q-loop/lid; other site
585397002393	ABC transporter signature motif; other site
585397002394	Walker B; other site
585397002395	D-loop; other site
585397002396	H-loop/switch region; other site
585397002397	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
585397002398	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397002399	dimer interface [polypeptide binding]; other site
585397002400	conserved gate region; other site
585397002401	putative PBP binding loops; other site
585397002402	ABC-ATPase subunit interface; other site
585397002403	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
585397002404	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585397002405	substrate binding pocket [chemical binding]; other site
585397002406	membrane-bound complex binding site; other site
585397002407	hinge residues; other site
585397002408	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
585397002409	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
585397002410	dimerization interface [polypeptide binding]; other site
585397002411	DPS ferroxidase diiron center [ion binding]; other site
585397002412	ion pore; other site
585397002413	fragment of threonine and homoserine efflux system (part 2);Evidence 7 : Gene remnant; Product type t : transporter
585397002414	fragment of threonine and homoserine efflux system (part 1);Evidence 7 : Gene remnant; Product type t : transporter
585397002415	outer membrane protein X; Provisional; Region: ompX; PRK09408
585397002416	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
585397002417	Sulfatase; Region: Sulfatase; pfam00884
585397002418	manganese transport regulator MntR; Provisional; Region: PRK11050
585397002419	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
585397002420	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
585397002421	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
585397002422	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
585397002423	transmembrane helices; other site
585397002424	L,D-transpeptidase; Provisional; Region: PRK10260
585397002425	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
585397002426	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
585397002427	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397002428	Walker A/P-loop; other site
585397002429	ATP binding site [chemical binding]; other site
585397002430	Q-loop/lid; other site
585397002431	ABC transporter signature motif; other site
585397002432	Walker B; other site
585397002433	D-loop; other site
585397002434	H-loop/switch region; other site
585397002435	ABC transporter; Region: ABC_tran_2; pfam12848
585397002436	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
585397002437	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
585397002438	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397002439	active site
585397002440	motif I; other site
585397002441	motif II; other site
585397002442	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397002443	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
585397002444	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
585397002445	dimer interface [polypeptide binding]; other site
585397002446	active site
585397002447	glycine loop; other site
585397002448	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
585397002449	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
585397002450	active site
585397002451	intersubunit interactions; other site
585397002452	catalytic residue [active]
585397002453	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
585397002454	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
585397002455	ATP binding site [chemical binding]; other site
585397002456	substrate interface [chemical binding]; other site
585397002457	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
585397002458	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
585397002459	dimer interface [polypeptide binding]; other site
585397002460	putative functional site; other site
585397002461	putative MPT binding site; other site
585397002462	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
585397002463	catalytic nucleophile [active]
585397002464	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
585397002465	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585397002466	Walker A/P-loop; other site
585397002467	ATP binding site [chemical binding]; other site
585397002468	Q-loop/lid; other site
585397002469	ABC transporter signature motif; other site
585397002470	Walker B; other site
585397002471	D-loop; other site
585397002472	H-loop/switch region; other site
585397002473	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
585397002474	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585397002475	Walker A/P-loop; other site
585397002476	ATP binding site [chemical binding]; other site
585397002477	Q-loop/lid; other site
585397002478	ABC transporter signature motif; other site
585397002479	Walker B; other site
585397002480	D-loop; other site
585397002481	H-loop/switch region; other site
585397002482	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
585397002483	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
585397002484	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
585397002485	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
585397002486	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397002487	dimer interface [polypeptide binding]; other site
585397002488	conserved gate region; other site
585397002489	putative PBP binding loops; other site
585397002490	ABC-ATPase subunit interface; other site
585397002491	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
585397002492	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
585397002493	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397002494	dimer interface [polypeptide binding]; other site
585397002495	conserved gate region; other site
585397002496	putative PBP binding loops; other site
585397002497	ABC-ATPase subunit interface; other site
585397002498	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585397002499	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
585397002500	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585397002501	metal binding site [ion binding]; metal-binding site
585397002502	active site
585397002503	I-site; other site
585397002504	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
585397002505	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
585397002506	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585397002507	FeS/SAM binding site; other site
585397002508	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
585397002509	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
585397002510	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
585397002511	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
585397002512	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
585397002513	putative C-terminal domain interface [polypeptide binding]; other site
585397002514	putative GSH binding site (G-site) [chemical binding]; other site
585397002515	putative dimer interface [polypeptide binding]; other site
585397002516	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
585397002517	N-terminal domain interface [polypeptide binding]; other site
585397002518	dimer interface [polypeptide binding]; other site
585397002519	substrate binding pocket (H-site) [chemical binding]; other site
585397002520	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
585397002521	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
585397002522	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
585397002523	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
585397002524	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
585397002525	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585397002526	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
585397002527	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
585397002528	active site
585397002529	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
585397002530	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397002531	putative substrate translocation pore; other site
585397002532	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
585397002533	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397002534	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
585397002535	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397002536	putative substrate translocation pore; other site
585397002537	Major Facilitator Superfamily; Region: MFS_1; pfam07690
585397002538	transcriptional repressor BetI; Region: betaine_BetI; TIGR03384
585397002539	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585397002540	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
585397002541	putative transporter; Provisional; Region: PRK04972
585397002542	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
585397002543	TrkA-C domain; Region: TrkA_C; pfam02080
585397002544	TrkA-C domain; Region: TrkA_C; pfam02080
585397002545	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
585397002546	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
585397002547	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
585397002548	GSH binding site [chemical binding]; other site
585397002549	catalytic residues [active]
585397002550	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
585397002551	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
585397002552	dimer interface [polypeptide binding]; other site
585397002553	FMN binding site [chemical binding]; other site
585397002554	NADPH bind site [chemical binding]; other site
585397002555	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
585397002556	RimK-like ATP-grasp domain; Region: RimK; pfam08443
585397002557	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
585397002558	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
585397002559	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
585397002560	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
585397002561	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397002562	Walker A/P-loop; other site
585397002563	ATP binding site [chemical binding]; other site
585397002564	Q-loop/lid; other site
585397002565	ABC transporter signature motif; other site
585397002566	Walker B; other site
585397002567	D-loop; other site
585397002568	H-loop/switch region; other site
585397002569	TOBE domain; Region: TOBE_2; pfam08402
585397002570	fragment of putrescine transporter subunit: membrane component of ABC superfamily (part 1);Evidence 7 : Gene remnant; Product type t : transporter
585397002571	fragment of putrescine transporter subunit: membrane component of ABC superfamily (part 2);Evidence 7 : Gene remnant; Product type t : transporter
585397002572	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
585397002573	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397002574	dimer interface [polypeptide binding]; other site
585397002575	conserved gate region; other site
585397002576	putative PBP binding loops; other site
585397002577	ABC-ATPase subunit interface; other site
585397002578	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
585397002579	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
585397002580	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397002581	S-adenosylmethionine binding site [chemical binding]; other site
585397002582	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
585397002583	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585397002584	substrate binding pocket [chemical binding]; other site
585397002585	membrane-bound complex binding site; other site
585397002586	hinge residues; other site
585397002587	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397002588	dimer interface [polypeptide binding]; other site
585397002589	conserved gate region; other site
585397002590	putative PBP binding loops; other site
585397002591	ABC-ATPase subunit interface; other site
585397002592	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
585397002593	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397002594	dimer interface [polypeptide binding]; other site
585397002595	conserved gate region; other site
585397002596	putative PBP binding loops; other site
585397002597	ABC-ATPase subunit interface; other site
585397002598	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
585397002599	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585397002600	substrate binding pocket [chemical binding]; other site
585397002601	membrane-bound complex binding site; other site
585397002602	hinge residues; other site
585397002603	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
585397002604	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397002605	Walker A/P-loop; other site
585397002606	ATP binding site [chemical binding]; other site
585397002607	Q-loop/lid; other site
585397002608	ABC transporter signature motif; other site
585397002609	Walker B; other site
585397002610	D-loop; other site
585397002611	H-loop/switch region; other site
585397002612	putative lipoprotein; Provisional; Region: PRK10533
585397002613	hypothetical protein; Provisional; Region: PRK02877
585397002614	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
585397002615	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
585397002616	amidase catalytic site [active]
585397002617	Zn binding residues [ion binding]; other site
585397002618	substrate binding site [chemical binding]; other site
585397002619	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
585397002620	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
585397002621	NAD(P) binding site [chemical binding]; other site
585397002622	active site
585397002623	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
585397002624	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
585397002625	putative NAD(P) binding site [chemical binding]; other site
585397002626	putative active site [active]
585397002627	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
585397002628	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
585397002629	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
585397002630	tetramer interface [polypeptide binding]; other site
585397002631	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397002632	catalytic residue [active]
585397002633	pyruvate dehydrogenase; Provisional; Region: PRK09124
585397002634	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
585397002635	PYR/PP interface [polypeptide binding]; other site
585397002636	dimer interface [polypeptide binding]; other site
585397002637	tetramer interface [polypeptide binding]; other site
585397002638	TPP binding site [chemical binding]; other site
585397002639	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
585397002640	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
585397002641	TPP-binding site [chemical binding]; other site
585397002642	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
585397002643	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
585397002644	FAD binding pocket [chemical binding]; other site
585397002645	FAD binding motif [chemical binding]; other site
585397002646	phosphate binding motif [ion binding]; other site
585397002647	beta-alpha-beta structure motif; other site
585397002648	NAD binding pocket [chemical binding]; other site
585397002649	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
585397002650	catalytic loop [active]
585397002651	iron binding site [ion binding]; other site
585397002652	hybrid cluster protein; Provisional; Region: PRK05290
585397002653	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
585397002654	ACS interaction site; other site
585397002655	CODH interaction site; other site
585397002656	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
585397002657	hybrid metal cluster; other site
585397002658	Predicted membrane protein [Function unknown]; Region: COG2431
585397002659	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
585397002660	amphipathic channel; other site
585397002661	Asn-Pro-Ala signature motifs; other site
585397002662	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
585397002663	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
585397002664	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
585397002665	putative active site [active]
585397002666	putative metal-binding site [ion binding]; other site
585397002667	Protein of unknown function (DUF535); Region: DUF535; pfam04393
585397002668	macrolide transporter subunit MacA; Provisional; Region: PRK11578
585397002669	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585397002670	HlyD family secretion protein; Region: HlyD_3; pfam13437
585397002671	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
585397002672	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
585397002673	Walker A/P-loop; other site
585397002674	ATP binding site [chemical binding]; other site
585397002675	Q-loop/lid; other site
585397002676	ABC transporter signature motif; other site
585397002677	Walker B; other site
585397002678	D-loop; other site
585397002679	H-loop/switch region; other site
585397002680	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
585397002681	FtsX-like permease family; Region: FtsX; pfam02687
585397002682	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
585397002683	DNA-binding site [nucleotide binding]; DNA binding site
585397002684	RNA-binding motif; other site
585397002685	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
585397002686	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
585397002687	Clp amino terminal domain; Region: Clp_N; pfam02861
585397002688	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397002689	Walker A motif; other site
585397002690	ATP binding site [chemical binding]; other site
585397002691	Walker B motif; other site
585397002692	arginine finger; other site
585397002693	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397002694	Walker A motif; other site
585397002695	ATP binding site [chemical binding]; other site
585397002696	Walker B motif; other site
585397002697	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
585397002698	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-F; cd09718
585397002699	CRISPR/Cas system-associated protein Cas3/Cas2; Region: Cas3_Cas2_I-F; cd09673
585397002700	CRISPR-associated helicase Cas3, subtype I-F/YPEST; Region: cas3_yersinia; TIGR02562
585397002701	CRISPR/Cas system-associated protein Csy1; Region: Csy1_I-F; cd09735
585397002702	CRISPR/Cas system-associated RAMP superfamily protein Csy2; Region: Csy2_I-F; cd09736
585397002703	CRISPR/Cas system-associated RAMP superfamily protein Csy3; Region: Csy3_I-F; cd09737
585397002704	CRISPR/Cas system-associated RAMP superfamily protein Cas6f; Region: Cas6_I-F; cd09739
585397002705	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
585397002706	rRNA binding site [nucleotide binding]; other site
585397002707	predicted 30S ribosome binding site; other site
585397002708	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
585397002709	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
585397002710	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
585397002711	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
585397002712	Walker A/P-loop; other site
585397002713	ATP binding site [chemical binding]; other site
585397002714	Q-loop/lid; other site
585397002715	ABC transporter signature motif; other site
585397002716	Walker B; other site
585397002717	D-loop; other site
585397002718	H-loop/switch region; other site
585397002719	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
585397002720	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
585397002721	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397002722	Walker A/P-loop; other site
585397002723	ATP binding site [chemical binding]; other site
585397002724	Q-loop/lid; other site
585397002725	ABC transporter signature motif; other site
585397002726	Walker B; other site
585397002727	D-loop; other site
585397002728	H-loop/switch region; other site
585397002729	thioredoxin reductase; Provisional; Region: PRK10262
585397002730	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
585397002731	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585397002732	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
585397002733	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
585397002734	putative DNA binding site [nucleotide binding]; other site
585397002735	putative Zn2+ binding site [ion binding]; other site
585397002736	AsnC family; Region: AsnC_trans_reg; pfam01037
585397002737	DNA translocase FtsK; Provisional; Region: PRK10263
585397002738	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
585397002739	DNA translocase FtsK; Provisional; Region: PRK10263
585397002740	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
585397002741	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
585397002742	periplasmic chaperone LolA; Region: lolA; TIGR00547
585397002743	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
585397002744	recombination factor protein RarA; Reviewed; Region: PRK13342
585397002745	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397002746	Walker A motif; other site
585397002747	ATP binding site [chemical binding]; other site
585397002748	Walker B motif; other site
585397002749	arginine finger; other site
585397002750	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
585397002751	seryl-tRNA synthetase; Provisional; Region: PRK05431
585397002752	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
585397002753	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
585397002754	dimer interface [polypeptide binding]; other site
585397002755	active site
585397002756	motif 1; other site
585397002757	motif 2; other site
585397002758	motif 3; other site
585397002759	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
585397002760	Protein of unknown function (DUF421); Region: DUF421; cl00990
585397002761	Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796
585397002762	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
585397002763	Phage tail tube protein FII; Region: Phage_tube; pfam04985
585397002764	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
585397002765	Phage protein U [General function prediction only]; Region: COG3499
585397002766	Domain of unknown function (DUF4376); Region: DUF4376; pfam14301
585397002767	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
585397002768	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
585397002769	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
585397002770	Phage tail protein (Tail_P2_I); Region: Tail_P2_I; cl01817
585397002771	Baseplate J-like protein; Region: Baseplate_J; cl01294
585397002772	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
585397002773	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
585397002774	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
585397002775	Phage virion morphogenesis family; Region: Phage_tail_S; cl02089
585397002776	Phage virion morphogenesis family; Region: Phage_tail_S; cl02089
585397002777	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
585397002778	Domain of unknown function (DUF1737); Region: DUF1737; cl10503
585397002779	Domain of unknown function (DUF303); Region: DUF303; pfam03629
585397002780	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
585397002781	catalytic residue [active]
585397002782	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
585397002783	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
585397002784	terminase endonuclease subunit; Provisional; Region: M; PHA02537
585397002785	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
585397002786	Phage major capsid protein, P2 family; Region: Phage_cap_P2; cl04947
585397002787	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; cl15838
585397002788	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
585397002789	terminase ATPase subunit; Provisional; Region: P; PHA02535
585397002790	Phage-related protein [Function unknown]; Region: COG4695; cl01923
585397002791	Phage portal protein; Region: Phage_portal; pfam04860
585397002792	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
585397002793	generic binding surface I; other site
585397002794	generic binding surface II; other site
585397002795	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
585397002796	Transposase; Region: HTH_Tnp_1; pfam01527
585397002797	putative transposase OrfB; Reviewed; Region: PHA02517
585397002798	Integrase core domain; Region: rve; pfam00665
585397002799	Integrase core domain; Region: rve_3; pfam13683
585397002800	MarR family; Region: MarR_2; cl17246
585397002801	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
585397002802	Domain of unknown function (DUF4406); Region: DUF4406; pfam14359
585397002803	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
585397002804	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
585397002805	sensor protein KdpD; Provisional; Region: PRK10490
585397002806	Regulatory phage protein cox; Region: Phage_Cox; pfam10743
585397002807	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397002808	non-specific DNA binding site [nucleotide binding]; other site
585397002809	salt bridge; other site
585397002810	sequence-specific DNA binding site [nucleotide binding]; other site
585397002811	integrase; Provisional; Region: int; PHA02601
585397002812	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
585397002813	active site
585397002814	DNA binding site [nucleotide binding]
585397002815	Int/Topo IB signature motif; other site
585397002816	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
585397002817	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
585397002818	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
585397002819	putative [Fe4-S4] binding site [ion binding]; other site
585397002820	putative molybdopterin cofactor binding site [chemical binding]; other site
585397002821	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
585397002822	putative molybdopterin cofactor binding site; other site
585397002823	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
585397002824	4Fe-4S binding domain; Region: Fer4; pfam00037
585397002825	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
585397002826	Isochorismatase family; Region: Isochorismatase; pfam00857
585397002827	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
585397002828	catalytic triad [active]
585397002829	dimer interface [polypeptide binding]; other site
585397002830	conserved cis-peptide bond; other site
585397002831	putative MFS family transporter protein; Provisional; Region: PRK03633
585397002832	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397002833	putative substrate translocation pore; other site
585397002834	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
585397002835	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585397002836	FeS/SAM binding site; other site
585397002837	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
585397002838	Pyruvate formate lyase 1; Region: PFL1; cd01678
585397002839	coenzyme A binding site [chemical binding]; other site
585397002840	active site
585397002841	catalytic residues [active]
585397002842	glycine loop; other site
585397002843	formate transporter; Provisional; Region: PRK10805
585397002844	uncharacterized domain; Region: TIGR00702
585397002845	YcaO-like family; Region: YcaO; pfam02624
585397002846	Predicted membrane protein [Function unknown]; Region: COG2323
585397002847	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
585397002848	homodimer interface [polypeptide binding]; other site
585397002849	substrate-cofactor binding pocket; other site
585397002850	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397002851	catalytic residue [active]
585397002852	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
585397002853	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
585397002854	hinge; other site
585397002855	active site
585397002856	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
585397002857	cytidylate kinase; Provisional; Region: cmk; PRK00023
585397002858	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
585397002859	CMP-binding site; other site
585397002860	The sites determining sugar specificity; other site
585397002861	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
585397002862	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
585397002863	RNA binding site [nucleotide binding]; other site
585397002864	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
585397002865	RNA binding site [nucleotide binding]; other site
585397002866	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
585397002867	RNA binding site [nucleotide binding]; other site
585397002868	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
585397002869	RNA binding site [nucleotide binding]; other site
585397002870	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
585397002871	RNA binding site [nucleotide binding]; other site
585397002872	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
585397002873	IHF dimer interface [polypeptide binding]; other site
585397002874	IHF - DNA interface [nucleotide binding]; other site
585397002875	ComEC family competence protein; Provisional; Region: PRK11539
585397002876	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
585397002877	ComEC/Rec2-related protein; Region: ComEC_N-term; TIGR00360
585397002878	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
585397002879	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
585397002880	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
585397002881	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
585397002882	Walker A/P-loop; other site
585397002883	ATP binding site [chemical binding]; other site
585397002884	Q-loop/lid; other site
585397002885	ABC transporter signature motif; other site
585397002886	Walker B; other site
585397002887	D-loop; other site
585397002888	H-loop/switch region; other site
585397002889	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
585397002890	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
585397002891	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
585397002892	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
585397002893	putative transposase OrfB; Reviewed; Region: PHA02517
585397002894	Integrase core domain; Region: rve; pfam00665
585397002895	Integrase core domain; Region: rve_3; pfam13683
585397002896	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
585397002897	Transposase; Region: HTH_Tnp_1; pfam01527
585397002898	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
585397002899	hypothetical protein; Provisional; Region: PRK11827
585397002900	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
585397002901	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
585397002902	Ligand binding site; other site
585397002903	oligomer interface; other site
585397002904	hypothetical protein; Provisional; Region: PRK10593
585397002905	Uncharacterized conserved protein [Function unknown]; Region: COG1434
585397002906	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
585397002907	putative active site [active]
585397002908	Methyltransferase domain; Region: Methyltransf_31; pfam13847
585397002909	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397002910	S-adenosylmethionine binding site [chemical binding]; other site
585397002911	condesin subunit F; Provisional; Region: PRK05260
585397002912	condesin subunit E; Provisional; Region: PRK05256
585397002913	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
585397002914	MukB N-terminal; Region: MukB; pfam04310
585397002915	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
585397002916	murein L,D-transpeptidase; Provisional; Region: PRK10594
585397002917	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
585397002918	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
585397002919	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
585397002920	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
585397002921	Peptidase M15; Region: Peptidase_M15_3; cl01194
585397002922	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
585397002923	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
585397002924	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585397002925	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397002926	homodimer interface [polypeptide binding]; other site
585397002927	catalytic residue [active]
585397002928	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
585397002929	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
585397002930	trimer interface [polypeptide binding]; other site
585397002931	eyelet of channel; other site
585397002932	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
585397002933	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
585397002934	putative dimer interface [polypeptide binding]; other site
585397002935	putative anticodon binding site; other site
585397002936	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
585397002937	homodimer interface [polypeptide binding]; other site
585397002938	motif 1; other site
585397002939	motif 2; other site
585397002940	active site
585397002941	motif 3; other site
585397002942	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
585397002943	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
585397002944	active site
585397002945	aminopeptidase N; Provisional; Region: pepN; PRK14015
585397002946	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
585397002947	active site
585397002948	Zn binding site [ion binding]; other site
585397002949	aliphatic sulfonates transport ATP-binding subunit; Provisional; Region: ssuB; PRK11247
585397002950	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
585397002951	Walker A/P-loop; other site
585397002952	ATP binding site [chemical binding]; other site
585397002953	Q-loop/lid; other site
585397002954	ABC transporter signature motif; other site
585397002955	Walker B; other site
585397002956	D-loop; other site
585397002957	H-loop/switch region; other site
585397002958	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
585397002959	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397002960	dimer interface [polypeptide binding]; other site
585397002961	conserved gate region; other site
585397002962	putative PBP binding loops; other site
585397002963	ABC-ATPase subunit interface; other site
585397002964	alkanesulfonate monooxygenase; Provisional; Region: PRK00719
585397002965	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
585397002966	active site
585397002967	dimer interface [polypeptide binding]; other site
585397002968	non-prolyl cis peptide bond; other site
585397002969	insertion regions; other site
585397002970	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585397002971	substrate binding pocket [chemical binding]; other site
585397002972	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
585397002973	membrane-bound complex binding site; other site
585397002974	hinge residues; other site
585397002975	NAD(P)H-dependent FMN reductase; Provisional; Region: PRK10569
585397002976	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
585397002977	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
585397002978	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
585397002979	quinone interaction residues [chemical binding]; other site
585397002980	active site
585397002981	catalytic residues [active]
585397002982	FMN binding site [chemical binding]; other site
585397002983	substrate binding site [chemical binding]; other site
585397002984	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
585397002985	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
585397002986	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
585397002987	MOSC domain; Region: MOSC; pfam03473
585397002988	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
585397002989	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
585397002990	catalytic loop [active]
585397002991	iron binding site [ion binding]; other site
585397002992	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
585397002993	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
585397002994	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
585397002995	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397002996	S-adenosylmethionine binding site [chemical binding]; other site
585397002997	ABC transporter ATPase component; Reviewed; Region: PRK11147
585397002998	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397002999	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397003000	Walker A/P-loop; other site
585397003001	Walker A/P-loop; other site
585397003002	ATP binding site [chemical binding]; other site
585397003003	ATP binding site [chemical binding]; other site
585397003004	Q-loop/lid; other site
585397003005	Q-loop/lid; other site
585397003006	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
585397003007	ABC transporter signature motif; other site
585397003008	Walker B; other site
585397003009	D-loop; other site
585397003010	ABC transporter; Region: ABC_tran_2; pfam12848
585397003011	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
585397003012	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
585397003013	Paraquat-inducible protein A; Region: PqiA; pfam04403
585397003014	Paraquat-inducible protein A; Region: PqiA; pfam04403
585397003015	paraquat-inducible protein B; Provisional; Region: PRK10807
585397003016	mce related protein; Region: MCE; pfam02470
585397003017	mce related protein; Region: MCE; pfam02470
585397003018	mce related protein; Region: MCE; pfam02470
585397003019	DASH complex subunit Duo1; Region: DASH_Duo1; pfam08651
585397003020	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
585397003021	Protein of unknown function (DUF330); Region: DUF330; pfam03886
585397003022	ribosome modulation factor; Provisional; Region: PRK14563
585397003023	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
585397003024	active site 1 [active]
585397003025	dimer interface [polypeptide binding]; other site
585397003026	active site 2 [active]
585397003027	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
585397003028	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
585397003029	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
585397003030	outer membrane protein A; Reviewed; Region: PRK10808
585397003031	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
585397003032	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
585397003033	ligand binding site [chemical binding]; other site
585397003034	SOS cell division inhibitor; Provisional; Region: PRK10595
585397003035	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
585397003036	TfoX C-terminal domain; Region: TfoX_C; pfam04994
585397003037	TIGR01666 family membrane protein; Region: YCCS
585397003038	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
585397003039	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
585397003040	Predicted membrane protein [Function unknown]; Region: COG3304
585397003041	Domain of unknown function (DUF307); Region: DUF307; pfam03733
585397003042	Domain of unknown function (DUF307); Region: DUF307; pfam03733
585397003043	DNA helicase IV; Provisional; Region: helD; PRK11054
585397003044	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
585397003045	Part of AAA domain; Region: AAA_19; pfam13245
585397003046	Family description; Region: UvrD_C_2; pfam13538
585397003047	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
585397003048	active site
585397003049	dimer interfaces [polypeptide binding]; other site
585397003050	catalytic residues [active]
585397003051	hypothetical protein; Provisional; Region: PRK03641
585397003052	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
585397003053	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
585397003054	heat shock protein HspQ; Provisional; Region: PRK14129
585397003055	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
585397003056	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
585397003057	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
585397003058	putative RNA binding site [nucleotide binding]; other site
585397003059	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397003060	S-adenosylmethionine binding site [chemical binding]; other site
585397003061	acylphosphatase; Provisional; Region: PRK14439
585397003062	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
585397003063	sulfur transfer protein TusE; Provisional; Region: PRK11508
585397003064	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
585397003065	YccA-like proteins; Region: YccA_like; cd10433
585397003066	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
585397003067	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
585397003068	dimer interface [polypeptide binding]; other site
585397003069	active site
585397003070	Int/Topo IB signature motif; other site
585397003071	Domain of unknown function (DUF4224); Region: DUF4224; pfam13986
585397003072	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
585397003073	active site
585397003074	catalytic site [active]
585397003075	substrate binding site [chemical binding]; other site
585397003076	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
585397003077	DicB protein; Region: DicB; pfam05358
585397003078	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
585397003079	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
585397003080	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397003081	non-specific DNA binding site [nucleotide binding]; other site
585397003082	salt bridge; other site
585397003083	sequence-specific DNA binding site [nucleotide binding]; other site
585397003084	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397003085	non-specific DNA binding site [nucleotide binding]; other site
585397003086	salt bridge; other site
585397003087	sequence-specific DNA binding site [nucleotide binding]; other site
585397003088	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
585397003089	Helix-turn-helix domain; Region: HTH_36; pfam13730
585397003090	primosomal protein DnaI; Provisional; Region: PRK02854
585397003091	putative replication protein; Provisional; Region: PRK12377
585397003092	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397003093	Walker A motif; other site
585397003094	ATP binding site [chemical binding]; other site
585397003095	Walker B motif; other site
585397003096	arginine finger; other site
585397003097	Protein of unknown function (DUF1627); Region: DUF1627; pfam07789
585397003098	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
585397003099	Hydrolase of X-linked nucleoside diphosphate N terminal; Region: Nudix_N; pfam12535
585397003100	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_14; cd04672
585397003101	nudix motif; other site
585397003102	putative phosphatase; Provisional; Region: PRK11587
585397003103	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397003104	active site
585397003105	motif I; other site
585397003106	motif II; other site
585397003107	hypothetical protein;Evidence 5 : No homology to any previously reported sequences
585397003108	Protein of unknown function (DUF968); Region: DUF968; pfam06147
585397003109	Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570
585397003110	Protein of unknown function (DUF1133); Region: DUF1133; pfam06576
585397003111	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397003112	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
585397003113	DNA methylase; Region: N6_N4_Mtase; pfam01555
585397003114	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
585397003115	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
585397003116	Domain of unknown function (DUF303); Region: DUF303; pfam03629
585397003117	Protein of unknown function (DUF826); Region: DUF826; pfam05696
585397003118	Lysis protein S; Region: Lysis_S; pfam04971
585397003119	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
585397003120	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
585397003121	catalytic residues [active]
585397003122	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
585397003123	Phage DNA packaging protein, Nu1 subunit of terminase [DNA replication, recombination, and repair]; Region: COG4220
585397003124	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
585397003125	gpW; Region: gpW; pfam02831
585397003126	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
585397003127	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
585397003128	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
585397003129	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
585397003130	tandem repeat interface [polypeptide binding]; other site
585397003131	oligomer interface [polypeptide binding]; other site
585397003132	active site residues [active]
585397003133	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
585397003134	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
585397003135	DNA packaging protein FI; Region: Packaging_FI; pfam14000
585397003136	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
585397003137	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
585397003138	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
585397003139	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
585397003140	Phage tail protein; Region: Phage_tail_3; pfam08813
585397003141	Bacterial Ig-like domain (group 2); Region: Big_2; cl02708
585397003142	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; pfam06894
585397003143	Minor tail protein T; Region: Phage_tail_T; cl05636
585397003144	Phage-related minor tail protein [Function unknown]; Region: COG5281
585397003145	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
585397003146	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
585397003147	Phage-related protein [Function unknown]; Region: COG4718
585397003148	Phage-related protein [Function unknown]; Region: gp18; COG4672
585397003149	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
585397003150	MPN+ (JAMM) motif; other site
585397003151	Zinc-binding site [ion binding]; other site
585397003152	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
585397003153	NlpC/P60 family; Region: NLPC_P60; cl17555
585397003154	Phage-related protein, tail component [Function unknown]; Region: COG4723
585397003155	Phage-related protein, tail component [Function unknown]; Region: COG4733
585397003156	Putative phage tail protein; Region: Phage-tail_3; pfam13550
585397003157	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
585397003158	Interdomain contacts; other site
585397003159	Cytokine receptor motif; other site
585397003160	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
585397003161	Fibronectin type III protein; Region: DUF3672; pfam12421
585397003162	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
585397003163	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
585397003164	Domain of unknown function (DUF4376); Region: DUF4376; pfam14301
585397003165	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
585397003166	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
585397003167	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
585397003168	hydrogenase 1 large subunit; Provisional; Region: PRK10170
585397003169	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
585397003170	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
585397003171	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
585397003172	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
585397003173	putative substrate-binding site; other site
585397003174	nickel binding site [ion binding]; other site
585397003175	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
585397003176	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
585397003177	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
585397003178	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
585397003179	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
585397003180	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
585397003181	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
585397003182	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
585397003183	catalytic core [active]
585397003184	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
585397003185	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
585397003186	DNA-binding site [nucleotide binding]; DNA binding site
585397003187	RNA-binding motif; other site
585397003188	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
585397003189	DNA-binding site [nucleotide binding]; DNA binding site
585397003190	RNA-binding motif; other site
585397003191	GnsA/GnsB family; Region: GnsAB; pfam08178
585397003192	4Fe-4S binding domain; Region: Fer4_5; pfam12801
585397003193	4Fe-4S binding domain; Region: Fer4_5; pfam12801
585397003194	Ferredoxin [Energy production and conversion]; Region: NapF; COG1145
585397003195	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
585397003196	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
585397003197	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
585397003198	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
585397003199	dimerization interface [polypeptide binding]; other site
585397003200	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585397003201	dimer interface [polypeptide binding]; other site
585397003202	phosphorylation site [posttranslational modification]
585397003203	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397003204	ATP binding site [chemical binding]; other site
585397003205	Mg2+ binding site [ion binding]; other site
585397003206	G-X-G motif; other site
585397003207	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397003208	active site
585397003209	phosphorylation site [posttranslational modification]
585397003210	intermolecular recognition site; other site
585397003211	dimerization interface [polypeptide binding]; other site
585397003212	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
585397003213	putative binding surface; other site
585397003214	active site
585397003215	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
585397003216	TorT-like proteins, a periplasmic binding protein family that activates induction of the Tor respiratory system upon trimethylamine N-oxide (TMAO) electron-acceptor binding in bacteria; Region: PBP1_TorT-like; cd06306
585397003217	putative ligand binding site [chemical binding]; other site
585397003218	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
585397003219	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397003220	active site
585397003221	phosphorylation site [posttranslational modification]
585397003222	intermolecular recognition site; other site
585397003223	dimerization interface [polypeptide binding]; other site
585397003224	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585397003225	DNA binding site [nucleotide binding]
585397003226	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
585397003227	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
585397003228	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
585397003229	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
585397003230	molybdopterin cofactor binding site [chemical binding]; other site
585397003231	substrate binding site [chemical binding]; other site
585397003232	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
585397003233	molybdopterin cofactor binding site; other site
585397003234	chaperone protein TorD; Validated; Region: torD; PRK04976
585397003235	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
585397003236	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
585397003237	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
585397003238	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
585397003239	HSP70 interaction site [polypeptide binding]; other site
585397003240	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
585397003241	substrate binding site [polypeptide binding]; other site
585397003242	dimer interface [polypeptide binding]; other site
585397003243	fragment of glucose-1-phosphatase/inositol phosphatase (part 1);Evidence 7 : Gene remnant; Product type e : enzyme
585397003244	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397003245	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397003246	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397003247	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397003248	fragment of glucose-1-phosphatase/inositol phosphatase (part 2);Evidence 7 : Gene remnant; Product type e : enzyme
585397003249	hypothetical protein; Provisional; Region: PRK10174
585397003250	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
585397003251	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
585397003252	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
585397003253	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
585397003254	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
585397003255	Int/Topo IB signature motif; other site
585397003256	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
585397003257	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
585397003258	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
585397003259	phage recombination protein Bet; Region: bet_lambda; TIGR01913
585397003260	Host-nuclease inhibitor protein Gam; Region: Gam; pfam06064
585397003261	exonuclease VIII; Reviewed; Region: PRK09709
585397003262	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
585397003263	FtsZ inhibitor protein; Reviewed; Region: kil; PRK11354
585397003264	Domain of unknown function DUF1828; Region: DUF1828; pfam08861
585397003265	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397003266	non-specific DNA binding site [nucleotide binding]; other site
585397003267	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
585397003268	salt bridge; other site
585397003269	sequence-specific DNA binding site [nucleotide binding]; other site
585397003270	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
585397003271	Catalytic site [active]
585397003272	Cro; Region: Cro; pfam09048
585397003273	Bacteriophage CII protein; Region: Phage_CII; pfam05269
585397003274	Pyruvate kinase, alpha/beta domain; Region: PK_C; pfam02887
585397003275	primosomal protein DnaI; Provisional; Region: PRK02854
585397003276	putative replication protein; Provisional; Region: PRK12377
585397003277	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397003278	Walker A motif; other site
585397003279	ATP binding site [chemical binding]; other site
585397003280	Protein of unknown function (DUF1627); Region: DUF1627; pfam07789
585397003281	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
585397003282	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
585397003283	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
585397003284	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397003285	salt bridge; other site
585397003286	non-specific DNA binding site [nucleotide binding]; other site
585397003287	sequence-specific DNA binding site [nucleotide binding]; other site
585397003288	Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973
585397003289	ORF6N domain; Region: ORF6N; pfam10543
585397003290	P22AR C-terminal domain; Region: P22_AR_C; pfam10548
585397003291	NinB protein; Region: NinB; pfam05772
585397003292	Endodeoxyribonuclease RusA; Region: RusA; cl01885
585397003293	Phage NinH protein; Region: Phage_NinH; pfam06322
585397003294	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
585397003295	Domain of unknown function (DUF303); Region: DUF303; pfam03629
585397003296	Protein of unknown function (DUF826); Region: DUF826; pfam05696
585397003297	Lysis protein S; Region: Lysis_S; pfam04971
585397003298	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
585397003299	catalytic residues [active]
585397003300	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
585397003301	Uncharacterized phage-encoded protein [Function unknown]; Region: COG3646
585397003302	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; cl10713
585397003303	ORF11CD3 domain; Region: ORF11CD3; pfam10549
585397003304	large terminase protein; Provisional; Region: 17; PHA02533
585397003305	large terminase protein; Provisional; Region: 17; PHA02533
585397003306	Protein of unknown function (DUF4043); Region: DUF4043; pfam13252
585397003307	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
585397003308	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
585397003309	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
585397003310	Domain of unknown function (DUF4376); Region: DUF4376; pfam14301
585397003311	YadA-like C-terminal region; Region: YadA; pfam03895
585397003312	Phage-related protein, tail component [Function unknown]; Region: COG4733
585397003313	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
585397003314	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
585397003315	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
585397003316	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
585397003317	ParB-like nuclease domain; Region: ParB; smart00470
585397003318	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
585397003319	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
585397003320	Active Sites [active]
585397003321	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
585397003322	Phage anti-repressor protein [Transcription]; Region: COG3561
585397003323	P22AR C-terminal domain; Region: P22_AR_C; pfam10548
585397003324	HNH endonuclease; Region: HNH_3; pfam13392
585397003325	General stress protein [General function prediction only]; Region: GsiB; COG3729
585397003326	pyrimidine utilization transport protein G; Region: RutG; TIGR03616
585397003327	pyrimidine utilization flavin reductase protein F; Region: RutF; TIGR03615
585397003328	Nitroreductase-like family 5.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_5; cd02148
585397003329	putative FMN binding site [chemical binding]; other site
585397003330	pyrimidine utilization protein D; Region: RutD; TIGR03611
585397003331	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
585397003332	homotrimer interaction site [polypeptide binding]; other site
585397003333	putative active site [active]
585397003334	Isochorismatase family; Region: Isochorismatase; pfam00857
585397003335	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
585397003336	catalytic triad [active]
585397003337	conserved cis-peptide bond; other site
585397003338	pyrimidine utilization protein A; Region: RutA; TIGR03612
585397003339	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
585397003340	active site
585397003341	dimer interface [polypeptide binding]; other site
585397003342	non-prolyl cis peptide bond; other site
585397003343	insertion regions; other site
585397003344	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
585397003345	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
585397003346	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585397003347	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
585397003348	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
585397003349	Predicted transcriptional regulator [Transcription]; Region: COG3905
585397003350	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
585397003351	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
585397003352	Glutamate binding site [chemical binding]; other site
585397003353	NAD binding site [chemical binding]; other site
585397003354	catalytic residues [active]
585397003355	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
585397003356	Na binding site [ion binding]; other site
585397003357	FTR1 family protein; Region: TIGR00145
585397003358	inactive ferrous ion transporter periplasmic protein EfeO; Provisional; Region: PRK10378
585397003359	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
585397003360	Imelysin; Region: Peptidase_M75; pfam09375
585397003361	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
585397003362	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
585397003363	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
585397003364	hypothetical protein; Provisional; Region: PRK10536
585397003365	Protein of unknown function (DUF2726); Region: DUF2726; pfam10881
585397003366	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
585397003367	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
585397003368	putative ligand binding site [chemical binding]; other site
585397003369	NAD binding site [chemical binding]; other site
585397003370	dimerization interface [polypeptide binding]; other site
585397003371	catalytic site [active]
585397003372	putative hydrolase; Validated; Region: PRK09248
585397003373	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
585397003374	active site
585397003375	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
585397003376	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
585397003377	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
585397003378	curli assembly protein CsgF; Provisional; Region: PRK10050
585397003379	curli assembly protein CsgE; Provisional; Region: PRK10386
585397003380	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
585397003381	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585397003382	DNA binding residues [nucleotide binding]
585397003383	dimerization interface [polypeptide binding]; other site
585397003384	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
585397003385	Curlin associated repeat; Region: Curlin_rpt; pfam07012
585397003386	Curlin associated repeat; Region: Curlin_rpt; pfam07012
585397003387	major curlin subunit; Provisional; Region: csgA; PRK10051
585397003388	Curlin associated repeat; Region: Curlin_rpt; pfam07012
585397003389	Curlin associated repeat; Region: Curlin_rpt; pfam07012
585397003390	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
585397003391	Fimbrial protein; Region: Fimbrial; cl01416
585397003392	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
585397003393	putative ADP-ribose binding site [chemical binding]; other site
585397003394	putative active site [active]
585397003395	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
585397003396	PLD-like domain; Region: PLDc_2; pfam13091
585397003397	putative active site [active]
585397003398	catalytic site [active]
585397003399	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
585397003400	PLD-like domain; Region: PLDc_2; pfam13091
585397003401	putative active site [active]
585397003402	catalytic site [active]
585397003403	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
585397003404	Acyltransferase family; Region: Acyl_transf_3; pfam01757
585397003405	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
585397003406	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
585397003407	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
585397003408	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
585397003409	Ligand binding site; other site
585397003410	DXD motif; other site
585397003411	lipoprotein; Provisional; Region: PRK10175
585397003412	secY/secA suppressor protein; Provisional; Region: PRK11467
585397003413	drug efflux system protein MdtG; Provisional; Region: PRK09874
585397003414	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397003415	putative substrate translocation pore; other site
585397003416	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
585397003417	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
585397003418	putative acyl-acceptor binding pocket; other site
585397003419	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
585397003420	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
585397003421	active site residue [active]
585397003422	hypothetical protein; Provisional; Region: PRK03757
585397003423	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
585397003424	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
585397003425	hydroxyglutarate oxidase; Provisional; Region: PRK11728
585397003426	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
585397003427	DNA damage-inducible protein I; Provisional; Region: PRK10597
585397003428	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
585397003429	active site
585397003430	substrate binding pocket [chemical binding]; other site
585397003431	dimer interface [polypeptide binding]; other site
585397003432	lipoprotein; Provisional; Region: PRK10598
585397003433	glutaredoxin 2; Provisional; Region: PRK10387
585397003434	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
585397003435	C-terminal domain interface [polypeptide binding]; other site
585397003436	GSH binding site (G-site) [chemical binding]; other site
585397003437	catalytic residues [active]
585397003438	putative dimer interface [polypeptide binding]; other site
585397003439	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
585397003440	N-terminal domain interface [polypeptide binding]; other site
585397003441	multidrug resistance protein MdtH; Provisional; Region: PRK11646
585397003442	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397003443	putative substrate translocation pore; other site
585397003444	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
585397003445	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
585397003446	hypothetical protein; Provisional; Region: PRK11239
585397003447	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
585397003448	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
585397003449	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
585397003450	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
585397003451	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
585397003452	MviN-like protein; Region: MVIN; pfam03023
585397003453	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
585397003454	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
585397003455	Flagellar basal body P-ring biosynthesis protein [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FlgA; COG1261
585397003456	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
585397003457	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
585397003458	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
585397003459	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
585397003460	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
585397003461	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
585397003462	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
585397003463	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
585397003464	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
585397003465	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
585397003466	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
585397003467	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
585397003468	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
585397003469	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
585397003470	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
585397003471	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
585397003472	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
585397003473	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
585397003474	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
585397003475	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
585397003476	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
585397003477	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
585397003478	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
585397003479	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
585397003480	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
585397003481	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
585397003482	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
585397003483	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
585397003484	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
585397003485	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
585397003486	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
585397003487	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
585397003488	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
585397003489	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
585397003490	homodimer interface [polypeptide binding]; other site
585397003491	oligonucleotide binding site [chemical binding]; other site
585397003492	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
585397003493	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
585397003494	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
585397003495	RNA binding surface [nucleotide binding]; other site
585397003496	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
585397003497	active site
585397003498	Maf-like protein; Region: Maf; pfam02545
585397003499	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
585397003500	active site
585397003501	dimer interface [polypeptide binding]; other site
585397003502	hypothetical protein; Provisional; Region: PRK11193
585397003503	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
585397003504	putative phosphate acyltransferase; Provisional; Region: PRK05331
585397003505	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
585397003506	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
585397003507	dimer interface [polypeptide binding]; other site
585397003508	active site
585397003509	CoA binding pocket [chemical binding]; other site
585397003510	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
585397003511	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
585397003512	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
585397003513	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
585397003514	NAD(P) binding site [chemical binding]; other site
585397003515	homotetramer interface [polypeptide binding]; other site
585397003516	homodimer interface [polypeptide binding]; other site
585397003517	active site
585397003518	acyl carrier protein; Provisional; Region: acpP; PRK00982
585397003519	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
585397003520	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
585397003521	dimer interface [polypeptide binding]; other site
585397003522	active site
585397003523	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
585397003524	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
585397003525	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397003526	catalytic residue [active]
585397003527	conserved hypothetical protein, YceG family; Region: TIGR00247
585397003528	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
585397003529	dimerization interface [polypeptide binding]; other site
585397003530	thymidylate kinase; Validated; Region: tmk; PRK00698
585397003531	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
585397003532	TMP-binding site; other site
585397003533	ATP-binding site [chemical binding]; other site
585397003534	DNA polymerase III subunit delta'; Validated; Region: PRK07993
585397003535	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
585397003536	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
585397003537	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
585397003538	active site
585397003539	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
585397003540	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
585397003541	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
585397003542	active site turn [active]
585397003543	phosphorylation site [posttranslational modification]
585397003544	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
585397003545	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585397003546	N-terminal plug; other site
585397003547	ligand-binding site [chemical binding]; other site
585397003548	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
585397003549	nucleotide binding site/active site [active]
585397003550	HIT family signature motif; other site
585397003551	catalytic residue [active]
585397003552	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
585397003553	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
585397003554	putative dimer interface [polypeptide binding]; other site
585397003555	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
585397003556	thiamine kinase; Region: ycfN_thiK; TIGR02721
585397003557	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
585397003558	active site
585397003559	substrate binding site [chemical binding]; other site
585397003560	ATP binding site [chemical binding]; other site
585397003561	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
585397003562	beta-hexosaminidase; Provisional; Region: PRK05337
585397003563	hypothetical protein; Provisional; Region: PRK04940
585397003564	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
585397003565	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585397003566	hypothetical protein; Provisional; Region: PRK11280
585397003567	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
585397003568	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585397003569	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
585397003570	L,D-transpeptidase; Provisional; Region: PRK10260
585397003571	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
585397003572	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
585397003573	transcription-repair coupling factor; Provisional; Region: PRK10689
585397003574	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
585397003575	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585397003576	ATP binding site [chemical binding]; other site
585397003577	putative Mg++ binding site [ion binding]; other site
585397003578	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585397003579	nucleotide binding region [chemical binding]; other site
585397003580	ATP-binding site [chemical binding]; other site
585397003581	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
585397003582	Predicted membrane protein [Function unknown]; Region: COG4763
585397003583	Acyltransferase family; Region: Acyl_transf_3; pfam01757
585397003584	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
585397003585	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
585397003586	FtsX-like permease family; Region: FtsX; pfam02687
585397003587	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
585397003588	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
585397003589	Walker A/P-loop; other site
585397003590	ATP binding site [chemical binding]; other site
585397003591	Q-loop/lid; other site
585397003592	ABC transporter signature motif; other site
585397003593	Walker B; other site
585397003594	D-loop; other site
585397003595	H-loop/switch region; other site
585397003596	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
585397003597	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
585397003598	FtsX-like permease family; Region: FtsX; pfam02687
585397003599	fructokinase; Reviewed; Region: PRK09557
585397003600	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
585397003601	nucleotide binding site [chemical binding]; other site
585397003602	NAD-dependent deacetylase; Provisional; Region: PRK00481
585397003603	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
585397003604	NAD+ binding site [chemical binding]; other site
585397003605	substrate binding site [chemical binding]; other site
585397003606	Zn binding site [ion binding]; other site
585397003607	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
585397003608	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
585397003609	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
585397003610	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
585397003611	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397003612	dimer interface [polypeptide binding]; other site
585397003613	conserved gate region; other site
585397003614	putative PBP binding loops; other site
585397003615	ABC-ATPase subunit interface; other site
585397003616	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
585397003617	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397003618	dimer interface [polypeptide binding]; other site
585397003619	conserved gate region; other site
585397003620	putative PBP binding loops; other site
585397003621	ABC-ATPase subunit interface; other site
585397003622	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
585397003623	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397003624	Walker A/P-loop; other site
585397003625	ATP binding site [chemical binding]; other site
585397003626	Q-loop/lid; other site
585397003627	ABC transporter signature motif; other site
585397003628	Walker B; other site
585397003629	D-loop; other site
585397003630	H-loop/switch region; other site
585397003631	TOBE domain; Region: TOBE_2; pfam08402
585397003632	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
585397003633	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
585397003634	metal binding site [ion binding]; metal-binding site
585397003635	dimer interface [polypeptide binding]; other site
585397003636	Uncharacterized conserved protein [Function unknown]; Region: COG2850
585397003637	Cupin-like domain; Region: Cupin_8; pfam13621
585397003638	sensor protein PhoQ; Provisional; Region: PRK10815
585397003639	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
585397003640	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
585397003641	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
585397003642	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397003643	ATP binding site [chemical binding]; other site
585397003644	Mg2+ binding site [ion binding]; other site
585397003645	G-X-G motif; other site
585397003646	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
585397003647	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397003648	active site
585397003649	phosphorylation site [posttranslational modification]
585397003650	intermolecular recognition site; other site
585397003651	dimerization interface [polypeptide binding]; other site
585397003652	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585397003653	DNA binding site [nucleotide binding]
585397003654	adenylosuccinate lyase; Provisional; Region: PRK09285
585397003655	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
585397003656	tetramer interface [polypeptide binding]; other site
585397003657	active site
585397003658	putative lysogenization regulator; Reviewed; Region: PRK00218
585397003659	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
585397003660	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
585397003661	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
585397003662	nudix motif; other site
585397003663	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
585397003664	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
585397003665	probable active site [active]
585397003666	isocitrate dehydrogenase; Validated; Region: PRK07362
585397003667	isocitrate dehydrogenase; Reviewed; Region: PRK07006
585397003668	fragment of phage integrase (partial);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585397003669	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397003670	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397003671	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397003672	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397003673	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
585397003674	fragment of Host specificity protein J (partial);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585397003675	fragment of Host specificity protein J of prophage (partial);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585397003676	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397003677	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397003678	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397003679	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397003680	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
585397003681	Transposase; Region: HTH_Tnp_1; pfam01527
585397003682	putative transposase OrfB; Reviewed; Region: PHA02517
585397003683	Integrase core domain; Region: rve; pfam00665
585397003684	Integrase core domain; Region: rve_3; pfam13683
585397003685	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
585397003686	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
585397003687	ABC-ATPase subunit  interface; other site
585397003688	dimer interface [polypeptide binding]; other site
585397003689	putative PBP binding regions; other site
585397003690	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
585397003691	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
585397003692	ABC-ATPase subunit  interface; other site
585397003693	dimer interface [polypeptide binding]; other site
585397003694	putative PBP binding regions; other site
585397003695	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
585397003696	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
585397003697	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
585397003698	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
585397003699	metal binding site [ion binding]; metal-binding site
585397003700	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
585397003701	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397003702	sequence-specific DNA binding site [nucleotide binding]; other site
585397003703	salt bridge; other site
585397003704	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585397003705	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
585397003706	Coenzyme A binding pocket [chemical binding]; other site
585397003707	fragment of isocitrate dehydrogenase, specific for NADP+; e14 prophage (partial);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585397003708	Protein of unknown function (DUF1398); Region: DUF1398; pfam07166
585397003709	transcriptional regulator MirA; Provisional; Region: PRK15043
585397003710	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
585397003711	DNA binding residues [nucleotide binding]
585397003712	Sensors of blue-light using FAD; Region: BLUF; smart01034
585397003713	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585397003714	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
585397003715	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
585397003716	fragment of conserved hypothetical protein; putative inner membrane protein (partial);Evidence 7 : Gene remnant; Product type pm : putative membrane component
585397003717	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
585397003718	Autotransporter beta-domain; Region: Autotransporter; cl17461
585397003719	fragment of adhesin-like autotransporter (partial);Evidence 7 : Gene remnant; Product type t : transporter
585397003720	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
585397003721	cell division inhibitor MinD; Provisional; Region: PRK10818
585397003722	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
585397003723	Switch I; other site
585397003724	Switch II; other site
585397003725	septum formation inhibitor; Reviewed; Region: minC; PRK03511
585397003726	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
585397003727	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
585397003728	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
585397003729	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
585397003730	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
585397003731	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
585397003732	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
585397003733	hypothetical protein; Provisional; Region: PRK10691
585397003734	hypothetical protein; Provisional; Region: PRK05170
585397003735	fragment of hemolysin E (partial);Evidence 7 : Gene remnant; Product type c : carrier
585397003736	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
585397003737	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
585397003738	Catalytic site [active]
585397003739	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
585397003740	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
585397003741	active site
585397003742	DNA binding site [nucleotide binding]
585397003743	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
585397003744	disulfide bond formation protein B; Provisional; Region: PRK01749
585397003745	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
585397003746	transmembrane helices; other site
585397003747	fatty acid metabolism regulator; Provisional; Region: PRK04984
585397003748	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585397003749	DNA-binding site [nucleotide binding]; DNA binding site
585397003750	FadR C-terminal domain; Region: FadR_C; pfam07840
585397003751	SpoVR family protein; Provisional; Region: PRK11767
585397003752	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
585397003753	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
585397003754	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585397003755	alanine racemase; Reviewed; Region: dadX; PRK03646
585397003756	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
585397003757	active site
585397003758	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
585397003759	substrate binding site [chemical binding]; other site
585397003760	catalytic residues [active]
585397003761	dimer interface [polypeptide binding]; other site
585397003762	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
585397003763	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
585397003764	TrkA-C domain; Region: TrkA_C; pfam02080
585397003765	Transporter associated domain; Region: CorC_HlyC; smart01091
585397003766	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
585397003767	dimer interface [polypeptide binding]; other site
585397003768	catalytic triad [active]
585397003769	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
585397003770	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
585397003771	N-acetyl-D-glucosamine binding site [chemical binding]; other site
585397003772	catalytic residue [active]
585397003773	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
585397003774	Flagellar regulator YcgR; Region: YcgR; pfam07317
585397003775	PilZ domain; Region: PilZ; pfam07238
585397003776	hypothetical protein; Provisional; Region: PRK10457
585397003777	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585397003778	N-terminal plug; other site
585397003779	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
585397003780	ligand-binding site [chemical binding]; other site
585397003781	molybdenum transport protein ModD; Provisional; Region: PRK06096
585397003782	ModD; Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase) present in some modABC operons in bacteria, which are involved in molybdate transport. In general, QPRTases are part of the de novo synthesis pathway of NAD in both prokaryotes and...; Region: modD_like; cd01573
585397003783	dimerization interface [polypeptide binding]; other site
585397003784	active site
585397003785	Methyltransferase domain; Region: Methyltransf_31; pfam13847
585397003786	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397003787	S-adenosylmethionine binding site [chemical binding]; other site
585397003788	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
585397003789	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
585397003790	Walker A/P-loop; other site
585397003791	ATP binding site [chemical binding]; other site
585397003792	Q-loop/lid; other site
585397003793	ABC transporter signature motif; other site
585397003794	Walker B; other site
585397003795	D-loop; other site
585397003796	H-loop/switch region; other site
585397003797	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
585397003798	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
585397003799	ABC-ATPase subunit  interface; other site
585397003800	dimer interface [polypeptide binding]; other site
585397003801	putative PBP binding regions; other site
585397003802	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
585397003803	Metal binding protein HemV-2.  These proteins are predicted to function as initial receptors in ABC transport of metal ions.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding...; Region: HemV-2; cd01147
585397003804	putative metal binding site [ion binding]; other site
585397003805	fragment of periplasmic trehalase (part 2);Evidence 7 : Gene remnant; Product type e : enzyme
585397003806	fragment of periplasmic trehalase (part 1);Evidence 7 : Gene remnant; Product type e : enzyme
585397003807	dihydroxyacetone kinase subunit M; Provisional; Region: PRK11377
585397003808	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3412
585397003809	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
585397003810	dimerization domain swap beta strand [polypeptide binding]; other site
585397003811	regulatory protein interface [polypeptide binding]; other site
585397003812	active site
585397003813	regulatory phosphorylation site [posttranslational modification]; other site
585397003814	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
585397003815	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
585397003816	dihydroxyacetone kinase subunit DhaL; Provisional; Region: PRK10005
585397003817	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK11468
585397003818	Dak1 domain; Region: Dak1; pfam02733
585397003819	DNA-binding transcriptional regulator DhaR; Provisional; Region: PRK11388
585397003820	PAS domain; Region: PAS; smart00091
585397003821	putative active site [active]
585397003822	heme pocket [chemical binding]; other site
585397003823	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397003824	Walker A motif; other site
585397003825	ATP binding site [chemical binding]; other site
585397003826	Walker B motif; other site
585397003827	arginine finger; other site
585397003828	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
585397003829	Probable pectinesterase/pectinesterase inhibitor; Region: PLN02708
585397003830	GTP-binding protein YchF; Reviewed; Region: PRK09601
585397003831	YchF GTPase; Region: YchF; cd01900
585397003832	G1 box; other site
585397003833	GTP/Mg2+ binding site [chemical binding]; other site
585397003834	Switch I region; other site
585397003835	G2 box; other site
585397003836	Switch II region; other site
585397003837	G3 box; other site
585397003838	G4 box; other site
585397003839	G5 box; other site
585397003840	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
585397003841	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
585397003842	putative active site [active]
585397003843	catalytic residue [active]
585397003844	hypothetical protein; Provisional; Region: PRK10692
585397003845	putative transporter; Provisional; Region: PRK11660
585397003846	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
585397003847	Sulfate transporter family; Region: Sulfate_transp; pfam00916
585397003848	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
585397003849	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
585397003850	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
585397003851	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
585397003852	active site
585397003853	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
585397003854	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
585397003855	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
585397003856	outer membrane lipoprotein LolB; Region: lolB; TIGR00548
585397003857	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
585397003858	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
585397003859	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
585397003860	tRNA; other site
585397003861	putative tRNA binding site [nucleotide binding]; other site
585397003862	putative NADP binding site [chemical binding]; other site
585397003863	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
585397003864	peptide chain release factor 1; Validated; Region: prfA; PRK00591
585397003865	This domain is found in peptide chain release factors; Region: PCRF; smart00937
585397003866	RF-1 domain; Region: RF-1; pfam00472
585397003867	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
585397003868	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397003869	hypothetical protein; Provisional; Region: PRK10278
585397003870	hypothetical protein; Provisional; Region: PRK10941
585397003871	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
585397003872	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
585397003873	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
585397003874	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
585397003875	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
585397003876	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
585397003877	cation transport regulator; Reviewed; Region: chaB; PRK09582
585397003878	Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism]; Region: ChaC; COG3703
585397003879	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
585397003880	putative active site pocket [active]
585397003881	dimerization interface [polypeptide binding]; other site
585397003882	putative catalytic residue [active]
585397003883	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
585397003884	putative invasin; Provisional; Region: PRK10177
585397003885	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
585397003886	transcriptional regulator NarL; Provisional; Region: PRK10651
585397003887	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397003888	active site
585397003889	phosphorylation site [posttranslational modification]
585397003890	intermolecular recognition site; other site
585397003891	dimerization interface [polypeptide binding]; other site
585397003892	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585397003893	DNA binding residues [nucleotide binding]
585397003894	dimerization interface [polypeptide binding]; other site
585397003895	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
585397003896	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
585397003897	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585397003898	dimerization interface [polypeptide binding]; other site
585397003899	Histidine kinase; Region: HisKA_3; pfam07730
585397003900	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397003901	ATP binding site [chemical binding]; other site
585397003902	Mg2+ binding site [ion binding]; other site
585397003903	G-X-G motif; other site
585397003904	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
585397003905	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
585397003906	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
585397003907	[4Fe-4S] binding site [ion binding]; other site
585397003908	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
585397003909	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
585397003910	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
585397003911	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
585397003912	molybdopterin cofactor binding site; other site
585397003913	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
585397003914	4Fe-4S binding domain; Region: Fer4; cl02805
585397003915	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
585397003916	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
585397003917	fragment of putative transposase (part 2);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585397003918	fragment of putative transposase (part 1);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585397003919	fragment of conserved hypothetical protein (part 1);Evidence 7 : Gene remnant
585397003920	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
585397003921	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
585397003922	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
585397003923	putative active site [active]
585397003924	putative substrate binding site [chemical binding]; other site
585397003925	putative cosubstrate binding site; other site
585397003926	catalytic site [active]
585397003927	SEC-C motif; Region: SEC-C; pfam02810
585397003928	hypothetical protein; Provisional; Region: PRK04233
585397003929	hypothetical protein; Provisional; Region: PRK10279
585397003930	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
585397003931	active site
585397003932	nucleophile elbow; other site
585397003933	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397003934	active site
585397003935	response regulator of RpoS; Provisional; Region: PRK10693
585397003936	phosphorylation site [posttranslational modification]
585397003937	intermolecular recognition site; other site
585397003938	dimerization interface [polypeptide binding]; other site
585397003939	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
585397003940	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
585397003941	active site
585397003942	tetramer interface; other site
585397003943	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
585397003944	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
585397003945	thymidine kinase; Provisional; Region: PRK04296
585397003946	fragment of transposase IS4 (part 2);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397003947	fragment of putative IS4 transposase; KpLE2 phage-like element (partial);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397003948	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
585397003949	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
585397003950	putative catalytic cysteine [active]
585397003951	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
585397003952	putative active site [active]
585397003953	metal binding site [ion binding]; metal-binding site
585397003954	hypothetical protein; Provisional; Region: PRK11111
585397003955	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
585397003956	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
585397003957	peptide binding site [polypeptide binding]; other site
585397003958	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
585397003959	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397003960	dimer interface [polypeptide binding]; other site
585397003961	conserved gate region; other site
585397003962	putative PBP binding loops; other site
585397003963	ABC-ATPase subunit interface; other site
585397003964	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
585397003965	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
585397003966	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397003967	dimer interface [polypeptide binding]; other site
585397003968	conserved gate region; other site
585397003969	putative PBP binding loops; other site
585397003970	ABC-ATPase subunit interface; other site
585397003971	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
585397003972	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585397003973	Walker A/P-loop; other site
585397003974	ATP binding site [chemical binding]; other site
585397003975	Q-loop/lid; other site
585397003976	ABC transporter signature motif; other site
585397003977	Walker B; other site
585397003978	D-loop; other site
585397003979	H-loop/switch region; other site
585397003980	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
585397003981	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
585397003982	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585397003983	Walker A/P-loop; other site
585397003984	ATP binding site [chemical binding]; other site
585397003985	Q-loop/lid; other site
585397003986	ABC transporter signature motif; other site
585397003987	Walker B; other site
585397003988	D-loop; other site
585397003989	H-loop/switch region; other site
585397003990	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
585397003991	dsDNA-mimic protein; Reviewed; Region: PRK05094
585397003992	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
585397003993	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
585397003994	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
585397003995	putative active site [active]
585397003996	catalytic site [active]
585397003997	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
585397003998	putative active site [active]
585397003999	catalytic site [active]
585397004000	voltage-gated potassium channel; Provisional; Region: PRK10537
585397004001	Ion channel; Region: Ion_trans_2; pfam07885
585397004002	TrkA-N domain; Region: TrkA_N; pfam02254
585397004003	YciI-like protein; Reviewed; Region: PRK11370
585397004004	transport protein TonB; Provisional; Region: PRK10819
585397004005	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
585397004006	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
585397004007	intracellular septation protein A; Reviewed; Region: PRK00259
585397004008	hypothetical protein; Provisional; Region: PRK02868
585397004009	outer membrane protein W; Provisional; Region: PRK10959
585397004010	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
585397004011	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
585397004012	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
585397004013	dimer interface [polypeptide binding]; other site
585397004014	active site
585397004015	Int/Topo IB signature motif; other site
585397004016	fragment of putative exonuclease from phage origin (partial);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585397004017	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397004018	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397004019	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397004020	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397004021	Centrosome localisation domain of Cep57; Region: Cep57_CLD; pfam14073
585397004022	Protein of unknown function (DUF968); Region: DUF968; pfam06147
585397004023	Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570
585397004024	Antitermination protein; Region: Antiterm; pfam03589
585397004025	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
585397004026	MarR family; Region: MarR_2; cl17246
585397004027	fragment of putative DNA adenine methyltransferase ( DNA methylase) from phage origin (part 1);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585397004028	fragment of putative DNA adenine methyltransferase ( DNA methylase) from phage origin (part 2);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585397004029	conserved hypothetical protein, putative TolA;Evidence 7 : Gene remnant; PubMedId : 2068069, 10404600, 8978668; Product type h : extrachromosomal origin
585397004030	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
585397004031	Domain of unknown function (DUF303); Region: DUF303; pfam03629
585397004032	Protein of unknown function (DUF826); Region: DUF826; pfam05696
585397004033	Lysis protein S; Region: Lysis_S; pfam04971
585397004034	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
585397004035	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
585397004036	catalytic residues [active]
585397004037	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
585397004038	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
585397004039	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
585397004040	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
585397004041	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
585397004042	active site
585397004043	Phage terminase, small subunit [DNA replication, recombination, and repair]; Region: XtmA; COG3728
585397004044	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
585397004045	Caudovirus prohead protease; Region: Peptidase_U35; pfam04586
585397004046	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
585397004047	Phage capsid family; Region: Phage_capsid; pfam05065
585397004048	Phage-related protein [Function unknown]; Region: COG4695
585397004049	phage portal protein, HK97 family; Region: portal_HK97; TIGR01537
585397004050	Carbohydrate binding domain; Region: CBM_5_12; pfam02839
585397004051	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
585397004052	oligomerization interface [polypeptide binding]; other site
585397004053	Bacteriophage head-tail adaptor [General function prediction only]; Region: COG5614
585397004054	phage protein, HK97 gp10 family; Region: phge_HK97_gp10; TIGR01725
585397004055	Protein of unknown function (DUF3168); Region: DUF3168; pfam11367
585397004056	Immunoglobulin I-set domain; Region: I-set; pfam07679
585397004057	Immunoglobulin domain; Region: Ig_2; pfam13895
585397004058	Phage tail assembly chaperone; Region: Phage_TAC; pfam06222
585397004059	Protein of unknown function (DUF4035); Region: DUF4035; pfam13227
585397004060	Phage-related minor tail protein [Function unknown]; Region: COG5281
585397004061	tape measure domain; Region: tape_meas_nterm; TIGR02675
585397004062	Tail length tape measure protein; Region: Phage_HK97_TLTM; pfam06120
585397004063	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
585397004064	Phage-related protein [Function unknown]; Region: COG4718
585397004065	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
585397004066	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
585397004067	trimer interface [polypeptide binding]; other site
585397004068	eyelet of channel; other site
585397004069	Phage-related protein [Function unknown]; Region: gp18; COG4672
585397004070	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
585397004071	MPN+ (JAMM) motif; other site
585397004072	Zinc-binding site [ion binding]; other site
585397004073	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
585397004074	NlpC/P60 family; Region: NLPC_P60; cl17555
585397004075	Phage-related protein, tail component [Function unknown]; Region: COG4723
585397004076	fragment of Host specificity protein J (partial);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585397004077	host specificity protein J from phage origin (part2);Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
585397004078	Enterobacterial Ail/Lom protein; Region: Ail_Lom; pfam06316
585397004079	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
585397004080	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
585397004081	Domain of unknown function (DUF4376); Region: DUF4376; pfam14301
585397004082	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3685
585397004083	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
585397004084	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
585397004085	substrate binding site [chemical binding]; other site
585397004086	active site
585397004087	catalytic residues [active]
585397004088	heterodimer interface [polypeptide binding]; other site
585397004089	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
585397004090	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
585397004091	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397004092	catalytic residue [active]
585397004093	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
585397004094	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
585397004095	active site
585397004096	ribulose/triose binding site [chemical binding]; other site
585397004097	phosphate binding site [ion binding]; other site
585397004098	substrate (anthranilate) binding pocket [chemical binding]; other site
585397004099	product (indole) binding pocket [chemical binding]; other site
585397004100	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
585397004101	active site
585397004102	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
585397004103	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
585397004104	glutamine binding [chemical binding]; other site
585397004105	catalytic triad [active]
585397004106	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
585397004107	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
585397004108	anthranilate synthase component I; Provisional; Region: PRK13564
585397004109	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
585397004110	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
585397004111	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
585397004112	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
585397004113	active site
585397004114	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
585397004115	hypothetical protein; Provisional; Region: PRK11630
585397004116	Predicted membrane protein (DUF2207); Region: DUF2207; pfam09972
585397004117	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
585397004118	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
585397004119	RNA binding surface [nucleotide binding]; other site
585397004120	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
585397004121	probable active site [active]
585397004122	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
585397004123	Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557
585397004124	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
585397004125	homodimer interface [polypeptide binding]; other site
585397004126	Walker A motif; other site
585397004127	ATP binding site [chemical binding]; other site
585397004128	hydroxycobalamin binding site [chemical binding]; other site
585397004129	Walker B motif; other site
585397004130	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
585397004131	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
585397004132	NADP binding site [chemical binding]; other site
585397004133	homodimer interface [polypeptide binding]; other site
585397004134	active site
585397004135	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
585397004136	putative inner membrane peptidase; Provisional; Region: PRK11778
585397004137	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
585397004138	tandem repeat interface [polypeptide binding]; other site
585397004139	oligomer interface [polypeptide binding]; other site
585397004140	active site residues [active]
585397004141	hypothetical protein; Provisional; Region: PRK11037
585397004142	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
585397004143	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
585397004144	active site
585397004145	interdomain interaction site; other site
585397004146	putative metal-binding site [ion binding]; other site
585397004147	nucleotide binding site [chemical binding]; other site
585397004148	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
585397004149	domain I; other site
585397004150	DNA binding groove [nucleotide binding]
585397004151	phosphate binding site [ion binding]; other site
585397004152	domain II; other site
585397004153	domain III; other site
585397004154	nucleotide binding site [chemical binding]; other site
585397004155	catalytic site [active]
585397004156	domain IV; other site
585397004157	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
585397004158	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
585397004159	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
585397004160	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
585397004161	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
585397004162	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397004163	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
585397004164	substrate binding site [chemical binding]; other site
585397004165	putative dimerization interface [polypeptide binding]; other site
585397004166	fragment of aconitate hydratase 1 (part 1);Evidence 7 : Gene remnant; Product type e : enzyme
585397004167	fragment of aconitate hydratase 1 (part 2);Evidence 7 : Gene remnant; Product type e : enzyme
585397004168	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
585397004169	dimerization interface [polypeptide binding]; other site
585397004170	active site
585397004171	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
585397004172	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
585397004173	active site
585397004174	Predicted membrane protein [Function unknown]; Region: COG3771
585397004175	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
585397004176	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
585397004177	TPR motif; other site
585397004178	binding surface
585397004179	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585397004180	binding surface
585397004181	TPR motif; other site
585397004182	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
585397004183	active site
585397004184	dimer interface [polypeptide binding]; other site
585397004185	translation initiation factor Sui1; Validated; Region: PRK06824
585397004186	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
585397004187	putative rRNA binding site [nucleotide binding]; other site
585397004188	lipoprotein; Provisional; Region: PRK10540
585397004189	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
585397004190	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
585397004191	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585397004192	hypothetical protein; Provisional; Region: PRK13658
585397004193	RNase II stability modulator; Provisional; Region: PRK10060
585397004194	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585397004195	putative active site [active]
585397004196	heme pocket [chemical binding]; other site
585397004197	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585397004198	metal binding site [ion binding]; metal-binding site
585397004199	active site
585397004200	I-site; other site
585397004201	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585397004202	exoribonuclease II; Provisional; Region: PRK05054
585397004203	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
585397004204	RNB domain; Region: RNB; pfam00773
585397004205	S1 RNA binding domain; Region: S1; pfam00575
585397004206	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
585397004207	Uncharacterized conserved protein [Function unknown]; Region: COG2128
585397004208	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
585397004209	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
585397004210	NAD binding site [chemical binding]; other site
585397004211	homotetramer interface [polypeptide binding]; other site
585397004212	homodimer interface [polypeptide binding]; other site
585397004213	substrate binding site [chemical binding]; other site
585397004214	active site
585397004215	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
585397004216	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585397004217	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
585397004218	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585397004219	HlyD family secretion protein; Region: HlyD_3; pfam13437
585397004220	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
585397004221	Protein export membrane protein; Region: SecD_SecF; cl14618
585397004222	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
585397004223	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
585397004224	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397004225	putative substrate translocation pore; other site
585397004226	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
585397004227	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585397004228	Walker A/P-loop; other site
585397004229	ATP binding site [chemical binding]; other site
585397004230	Q-loop/lid; other site
585397004231	ABC transporter signature motif; other site
585397004232	Walker B; other site
585397004233	D-loop; other site
585397004234	H-loop/switch region; other site
585397004235	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
585397004236	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585397004237	Walker A/P-loop; other site
585397004238	ATP binding site [chemical binding]; other site
585397004239	Q-loop/lid; other site
585397004240	ABC transporter signature motif; other site
585397004241	Walker B; other site
585397004242	D-loop; other site
585397004243	H-loop/switch region; other site
585397004244	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
585397004245	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
585397004246	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
585397004247	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397004248	dimer interface [polypeptide binding]; other site
585397004249	conserved gate region; other site
585397004250	putative PBP binding loops; other site
585397004251	ABC-ATPase subunit interface; other site
585397004252	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
585397004253	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397004254	dimer interface [polypeptide binding]; other site
585397004255	conserved gate region; other site
585397004256	putative PBP binding loops; other site
585397004257	ABC-ATPase subunit interface; other site
585397004258	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
585397004259	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
585397004260	peptide binding site [polypeptide binding]; other site
585397004261	Protein of unknown function (DUF2543); Region: DUF2543; pfam10820
585397004262	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
585397004263	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397004264	Walker A motif; other site
585397004265	ATP binding site [chemical binding]; other site
585397004266	Walker B motif; other site
585397004267	arginine finger; other site
585397004268	phage shock protein PspA; Provisional; Region: PRK10698
585397004269	phage shock protein B; Provisional; Region: pspB; PRK09458
585397004270	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
585397004271	phage shock protein C; Region: phageshock_pspC; TIGR02978
585397004272	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
585397004273	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
585397004274	active site residue [active]
585397004275	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
585397004276	sucrose phosphorylase; Provisional; Region: PRK13840
585397004277	active site
585397004278	homodimer interface [polypeptide binding]; other site
585397004279	catalytic site [active]
585397004280	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
585397004281	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
585397004282	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
585397004283	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397004284	dimer interface [polypeptide binding]; other site
585397004285	conserved gate region; other site
585397004286	putative PBP binding loops; other site
585397004287	ABC-ATPase subunit interface; other site
585397004288	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
585397004289	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397004290	dimer interface [polypeptide binding]; other site
585397004291	conserved gate region; other site
585397004292	putative PBP binding loops; other site
585397004293	ABC-ATPase subunit interface; other site
585397004294	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
585397004295	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide and other MDR family members; Region: 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_; cd08255
585397004296	putative NAD(P) binding site [chemical binding]; other site
585397004297	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
585397004298	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
585397004299	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
585397004300	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
585397004301	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
585397004302	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
585397004303	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
585397004304	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
585397004305	beta-phosphoglucomutase; Region: bPGM; TIGR01990
585397004306	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397004307	motif II; other site
585397004308	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
585397004309	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
585397004310	Walker A/P-loop; other site
585397004311	ATP binding site [chemical binding]; other site
585397004312	Q-loop/lid; other site
585397004313	ABC transporter signature motif; other site
585397004314	Walker B; other site
585397004315	D-loop; other site
585397004316	H-loop/switch region; other site
585397004317	TOBE domain; Region: TOBE_2; pfam08402
585397004318	Outer membrane protein G (OmpG); Region: Porin_OmpG; pfam09381
585397004319	Transcriptional regulators [Transcription]; Region: PurR; COG1609
585397004320	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585397004321	DNA binding site [nucleotide binding]
585397004322	domain linker motif; other site
585397004323	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
585397004324	putative dimerization interface [polypeptide binding]; other site
585397004325	putative ligand binding site [chemical binding]; other site
585397004326	Predicted ATPase [General function prediction only]; Region: COG3106
585397004327	hypothetical protein; Provisional; Region: PRK05415
585397004328	TIGR01620 family protein; Region: hyp_HI0043
585397004329	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
585397004330	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
585397004331	putative aromatic amino acid binding site; other site
585397004332	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397004333	Walker A motif; other site
585397004334	ATP binding site [chemical binding]; other site
585397004335	Walker B motif; other site
585397004336	arginine finger; other site
585397004337	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
585397004338	dimer interface [polypeptide binding]; other site
585397004339	catalytic triad [active]
585397004340	peroxidatic and resolving cysteines [active]
585397004341	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
585397004342	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
585397004343	active site
585397004344	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
585397004345	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
585397004346	putative active site [active]
585397004347	Zn binding site [ion binding]; other site
585397004348	atypical (a) SDRs, subgroup 6; Region: SDR_a6; cd05267
585397004349	NADH(P)-binding; Region: NAD_binding_10; pfam13460
585397004350	putative NAD(P) binding site [chemical binding]; other site
585397004351	fragment of putative hydrolase (part 2);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397004352	fragment of putative hydrolase (part 1);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397004353	fragment of putative hydrolase (part 1);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397004354	Transcriptional regulator [Transcription]; Region: LysR; COG0583
585397004355	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397004356	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
585397004357	putative effector binding pocket; other site
585397004358	putative dimerization interface [polypeptide binding]; other site
585397004359	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
585397004360	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
585397004361	peptide binding site [polypeptide binding]; other site
585397004362	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
585397004363	Mechanosensitive ion channel; Region: MS_channel; pfam00924
585397004364	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
585397004365	universal stress protein UspE; Provisional; Region: PRK11175
585397004366	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
585397004367	Ligand Binding Site [chemical binding]; other site
585397004368	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
585397004369	Ligand Binding Site [chemical binding]; other site
585397004370	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
585397004371	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
585397004372	ligand binding site [chemical binding]; other site
585397004373	flexible hinge region; other site
585397004374	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
585397004375	putative switch regulator; other site
585397004376	non-specific DNA interactions [nucleotide binding]; other site
585397004377	DNA binding site [nucleotide binding]
585397004378	sequence specific DNA binding site [nucleotide binding]; other site
585397004379	putative cAMP binding site [chemical binding]; other site
585397004380	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
585397004381	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
585397004382	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
585397004383	DNA binding site [nucleotide binding]
585397004384	active site
585397004385	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl15356
585397004386	Cupin domain; Region: Cupin_2; cl17218
585397004387	Helix-turn-helix domain; Region: HTH_18; pfam12833
585397004388	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
585397004389	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585397004390	HlyD family secretion protein; Region: HlyD_3; pfam13437
585397004391	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
585397004392	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397004393	putative substrate translocation pore; other site
585397004394	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397004395	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
585397004396	Smr domain; Region: Smr; pfam01713
585397004397	PAS domain S-box; Region: sensory_box; TIGR00229
585397004398	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585397004399	putative active site [active]
585397004400	heme pocket [chemical binding]; other site
585397004401	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
585397004402	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585397004403	metal binding site [ion binding]; metal-binding site
585397004404	active site
585397004405	I-site; other site
585397004406	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
585397004407	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
585397004408	Cl binding site [ion binding]; other site
585397004409	oligomer interface [polypeptide binding]; other site
585397004410	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
585397004411	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
585397004412	ATP binding site [chemical binding]; other site
585397004413	Mg++ binding site [ion binding]; other site
585397004414	motif III; other site
585397004415	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585397004416	nucleotide binding region [chemical binding]; other site
585397004417	ATP-binding site [chemical binding]; other site
585397004418	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
585397004419	putative RNA binding site [nucleotide binding]; other site
585397004420	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
585397004421	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
585397004422	Ligand Binding Site [chemical binding]; other site
585397004423	fragment of integrase; Rac prophage (partial);Evidence 7 : Gene remnant; Product type e : enzyme
585397004424	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
585397004425	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
585397004426	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
585397004427	Ligand Binding Site [chemical binding]; other site
585397004428	fragment of outer membrane pore protein N, non-specific (part 2);Evidence 7 : Gene remnant; Product type t : transporter
585397004429	fragment of outer membrane pore protein N, non-specific (part 1);Evidence 7 : Gene remnant; Product type t : transporter
585397004430	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
585397004431	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
585397004432	dimer interface [polypeptide binding]; other site
585397004433	PYR/PP interface [polypeptide binding]; other site
585397004434	TPP binding site [chemical binding]; other site
585397004435	substrate binding site [chemical binding]; other site
585397004436	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
585397004437	Domain of unknown function; Region: EKR; smart00890
585397004438	4Fe-4S binding domain; Region: Fer4_6; pfam12837
585397004439	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
585397004440	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
585397004441	TPP-binding site [chemical binding]; other site
585397004442	dimer interface [polypeptide binding]; other site
585397004443	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
585397004444	Domain of unknown function (DUF333); Region: DUF333; pfam03891
585397004445	heat-inducible protein; Provisional; Region: PRK10449
585397004446	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
585397004447	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
585397004448	putative ligand binding site [chemical binding]; other site
585397004449	putative NAD binding site [chemical binding]; other site
585397004450	catalytic site [active]
585397004451	hypothetical protein; Provisional; Region: PRK10695
585397004452	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
585397004453	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
585397004454	Autotransporter beta-domain; Region: Autotransporter; pfam03797
585397004455	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
585397004456	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
585397004457	active site
585397004458	catalytic tetrad [active]
585397004459	azoreductase; Reviewed; Region: PRK00170
585397004460	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
585397004461	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
585397004462	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585397004463	ATP binding site [chemical binding]; other site
585397004464	putative Mg++ binding site [ion binding]; other site
585397004465	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585397004466	nucleotide binding region [chemical binding]; other site
585397004467	ATP-binding site [chemical binding]; other site
585397004468	Helicase associated domain (HA2); Region: HA2; pfam04408
585397004469	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
585397004470	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
585397004471	Uncharacterized conserved protein [Function unknown]; Region: COG1434
585397004472	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
585397004473	putative active site [active]
585397004474	Escherichia coli lactaldehyde dehydrogenase AldA-like; Region: ALDH_LactADH-AldA; cd07088
585397004475	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
585397004476	NAD binding site [chemical binding]; other site
585397004477	catalytic residues [active]
585397004478	substrate binding site [chemical binding]; other site
585397004479	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
585397004480	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
585397004481	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
585397004482	cytochrome b561; Provisional; Region: PRK11513
585397004483	hypothetical protein; Provisional; Region: PRK10040
585397004484	fragment of methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor (partial);Evidence 7 : Gene remnant; Product type r : regulator
585397004485	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
585397004486	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397004487	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
585397004488	dimerization interface [polypeptide binding]; other site
585397004489	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
585397004490	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
585397004491	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
585397004492	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
585397004493	hypothetical protein; Provisional; Region: PRK11415
585397004494	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
585397004495	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585397004496	Coenzyme A binding pocket [chemical binding]; other site
585397004497	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
585397004498	putative trimer interface [polypeptide binding]; other site
585397004499	putative CoA binding site [chemical binding]; other site
585397004500	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
585397004501	putative trimer interface [polypeptide binding]; other site
585397004502	putative CoA binding site [chemical binding]; other site
585397004503	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
585397004504	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
585397004505	gating phenylalanine in ion channel; other site
585397004506	tellurite resistance protein TehB; Provisional; Region: PRK11207
585397004507	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397004508	S-adenosylmethionine binding site [chemical binding]; other site
585397004509	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
585397004510	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
585397004511	benzoate transporter; Region: benE; TIGR00843
585397004512	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
585397004513	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397004514	non-specific DNA binding site [nucleotide binding]; other site
585397004515	salt bridge; other site
585397004516	sequence-specific DNA binding site [nucleotide binding]; other site
585397004517	Cupin domain; Region: Cupin_2; pfam07883
585397004518	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
585397004519	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
585397004520	Peptidase family U32; Region: Peptidase_U32; pfam01136
585397004521	Collagenase; Region: DUF3656; pfam12392
585397004522	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
585397004523	fragment of putative DNA-binding transcriptional regulator (partial);Evidence 7 : Gene remnant; Product type pr : putative regulator
585397004524	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
585397004525	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585397004526	DNA-binding site [nucleotide binding]; DNA binding site
585397004527	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585397004528	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397004529	homodimer interface [polypeptide binding]; other site
585397004530	catalytic residue [active]
585397004531	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
585397004532	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
585397004533	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
585397004534	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397004535	Walker A/P-loop; other site
585397004536	ATP binding site [chemical binding]; other site
585397004537	Q-loop/lid; other site
585397004538	ABC transporter signature motif; other site
585397004539	Walker B; other site
585397004540	D-loop; other site
585397004541	H-loop/switch region; other site
585397004542	TOBE domain; Region: TOBE_2; pfam08402
585397004543	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397004544	dimer interface [polypeptide binding]; other site
585397004545	conserved gate region; other site
585397004546	putative PBP binding loops; other site
585397004547	ABC-ATPase subunit interface; other site
585397004548	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
585397004549	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397004550	ABC-ATPase subunit interface; other site
585397004551	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
585397004552	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
585397004553	tetrameric interface [polypeptide binding]; other site
585397004554	NAD binding site [chemical binding]; other site
585397004555	catalytic residues [active]
585397004556	substrate binding site [chemical binding]; other site
585397004557	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
585397004558	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
585397004559	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
585397004560	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
585397004561	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
585397004562	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
585397004563	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
585397004564	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585397004565	N-terminal plug; other site
585397004566	ligand-binding site [chemical binding]; other site
585397004567	PQQ-like domain; Region: PQQ_2; pfam13360
585397004568	L-asparagine permease; Provisional; Region: PRK15049
585397004569	fragment of putative enzyme with similarity with GST (part 1);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397004570	fragment of putative enzyme with similarity with GST (part 2);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397004571	fragment of putative enzyme with similarity with GST (part 3);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397004572	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
585397004573	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
585397004574	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
585397004575	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
585397004576	Peptidase M35-like domain of uncharacterized proteins; Region: M35_like_1; cd11007
585397004577	putative active site [active]
585397004578	putative Zn binding site [ion binding]; other site
585397004579	fragment of putative H repeat-associated protein (partial);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585397004580	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
585397004581	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
585397004582	hypothetical protein; Provisional; Region: PRK10281
585397004583	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
585397004584	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
585397004585	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
585397004586	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
585397004587	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
585397004588	[4Fe-4S] binding site [ion binding]; other site
585397004589	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
585397004590	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
585397004591	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
585397004592	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
585397004593	molybdopterin cofactor binding site; other site
585397004594	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
585397004595	aromatic amino acid exporter; Provisional; Region: PRK11689
585397004596	formate dehydrogenase, alpha subunit, proteobacterial-type; Region: formate-DH-alph; TIGR01553
585397004597	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
585397004598	[4Fe-4S] binding site [ion binding]; other site
585397004599	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
585397004600	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
585397004601	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
585397004602	molybdopterin cofactor binding site; other site
585397004603	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
585397004604	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
585397004605	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
585397004606	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
585397004607	fragment of putative DNA-binding transcriptional regulator (partial);Evidence 7 : Gene remnant; Product type pr : putative regulator
585397004608	Plasmid maintenance system killer protein; Region: Plasmid_killer; pfam05015
585397004609	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
585397004610	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
585397004611	NAD binding site [chemical binding]; other site
585397004612	substrate binding site [chemical binding]; other site
585397004613	catalytic Zn binding site [ion binding]; other site
585397004614	tetramer interface [polypeptide binding]; other site
585397004615	structural Zn binding site [ion binding]; other site
585397004616	malate dehydrogenase; Provisional; Region: PRK13529
585397004617	Malic enzyme, N-terminal domain; Region: malic; pfam00390
585397004618	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
585397004619	NAD(P) binding site [chemical binding]; other site
585397004620	Putative biofilm-dependent modulation protein; Region: BDM; cl11581
585397004621	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
585397004622	cyclic-di-GMP phosphodiesterase; Provisional; Region: PRK11359
585397004623	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585397004624	putative active site [active]
585397004625	heme pocket [chemical binding]; other site
585397004626	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585397004627	putative active site [active]
585397004628	heme pocket [chemical binding]; other site
585397004629	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585397004630	metal binding site [ion binding]; metal-binding site
585397004631	active site
585397004632	I-site; other site
585397004633	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585397004634	fragment of putative diguanylate cyclase YddV;Evidence 7 : Gene remnant
585397004635	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
585397004636	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
585397004637	glutamate:gamma-aminobutyrate antiporter; Region: 2A0307_GadC; TIGR00910
585397004638	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
585397004639	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397004640	catalytic residue [active]
585397004641	fragment of putative membrane-associated peptidase (partial);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397004642	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
585397004643	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585397004644	FeS/SAM binding site; other site
585397004645	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
585397004646	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
585397004647	Sulfatase; Region: Sulfatase; pfam00884
585397004648	transcriptional regulator YdeO; Provisional; Region: PRK09940
585397004649	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397004650	putative oxidoreductase; Provisional; Region: PRK09939
585397004651	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
585397004652	putative molybdopterin cofactor binding site [chemical binding]; other site
585397004653	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
585397004654	putative molybdopterin cofactor binding site; other site
585397004655	fragment of putative fimbrial-like exported adhesin protein (partial);Evidence 7 : Gene remnant; Product type ps : putative structure
585397004656	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
585397004657	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585397004658	PapC C-terminal domain; Region: PapC_C; pfam13953
585397004659	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
585397004660	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585397004661	HipA N-terminal domain; Region: Couple_hipA; pfam13657
585397004662	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
585397004663	HipA-like N-terminal domain; Region: HipA_N; pfam07805
585397004664	HipA-like C-terminal domain; Region: HipA_C; pfam07804
585397004665	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
585397004666	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397004667	non-specific DNA binding site [nucleotide binding]; other site
585397004668	salt bridge; other site
585397004669	sequence-specific DNA binding site [nucleotide binding]; other site
585397004670	fragment of trans-aconitate methyltransferase (partial);Evidence 7 : Gene remnant; Product type e : enzyme
585397004671	fragment of conserved hypothetical protein; putative inner membrane protein (partial);Evidence 7 : Gene remnant; Product type pm : putative membrane component
585397004672	altronate oxidoreductase; Provisional; Region: PRK03643
585397004673	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
585397004674	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
585397004675	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
585397004676	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
585397004677	NAD(P) binding site [chemical binding]; other site
585397004678	catalytic residues [active]
585397004679	Transcriptional regulator [Transcription]; Region: LysR; COG0583
585397004680	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397004681	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
585397004682	putative dimerization interface [polypeptide binding]; other site
585397004683	putative arabinose transporter; Provisional; Region: PRK03545
585397004684	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397004685	putative substrate translocation pore; other site
585397004686	inner membrane protein; Provisional; Region: PRK10995
585397004687	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
585397004688	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
585397004689	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
585397004690	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397004691	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397004692	hypothetical protein; Provisional; Region: PRK10106
585397004693	6-phospho-beta-glucosidase; Reviewed; Region: celA; PRK09589
585397004694	beta-galactosidase; Region: BGL; TIGR03356
585397004695	fragment of putative DNA-binding transcriptional regulator HTH family (partial);Evidence 7 : Gene remnant; Product type pr : putative regulator
585397004696	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
585397004697	EamA-like transporter family; Region: EamA; pfam00892
585397004698	EamA-like transporter family; Region: EamA; pfam00892
585397004699	putative transporter; Provisional; Region: PRK10054
585397004700	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397004701	putative substrate translocation pore; other site
585397004702	diguanylate cyclase; Provisional; Region: PRK09894
585397004703	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
585397004704	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585397004705	metal binding site [ion binding]; metal-binding site
585397004706	active site
585397004707	I-site; other site
585397004708	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
585397004709	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
585397004710	active site
585397004711	Zn binding site [ion binding]; other site
585397004712	malonic semialdehyde reductase; Provisional; Region: PRK10538
585397004713	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
585397004714	putative NAD(P) binding site [chemical binding]; other site
585397004715	homodimer interface [polypeptide binding]; other site
585397004716	homotetramer interface [polypeptide binding]; other site
585397004717	active site
585397004718	Transcriptional regulators [Transcription]; Region: GntR; COG1802
585397004719	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585397004720	DNA-binding site [nucleotide binding]; DNA binding site
585397004721	FCD domain; Region: FCD; pfam07729
585397004722	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
585397004723	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
585397004724	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
585397004725	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
585397004726	fragment of putative transporter (part 2);Evidence 7 : Gene remnant; Product type pt : putative transporter
585397004727	putative transposase OrfB; Reviewed; Region: PHA02517
585397004728	Integrase core domain; Region: rve; pfam00665
585397004729	Integrase core domain; Region: rve_3; pfam13683
585397004730	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
585397004731	Transposase; Region: HTH_Tnp_1; pfam01527
585397004732	fragment of putative transporter (part 1);Evidence 7 : Gene remnant; Product type pt : putative transporter
585397004733	DinI-like family; Region: DinI; pfam06183
585397004734	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
585397004735	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cl00185
585397004736	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
585397004737	Autotransporter beta-domain; Region: Autotransporter; pfam03797
585397004738	YadA-like C-terminal region; Region: YadA; pfam03895
585397004739	Domain of unknown function (DUF4376); Region: DUF4376; pfam14301
585397004740	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
585397004741	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
585397004742	Phage-related protein, tail component [Function unknown]; Region: COG4733
585397004743	Putative phage tail protein; Region: Phage-tail_3; pfam13550
585397004744	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
585397004745	Interdomain contacts; other site
585397004746	Cytokine receptor motif; other site
585397004747	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
585397004748	Fibronectin type III protein; Region: DUF3672; pfam12421
585397004749	Phage-related protein, tail component [Function unknown]; Region: COG4723
585397004750	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
585397004751	MPN+ (JAMM) motif; other site
585397004752	Zinc-binding site [ion binding]; other site
585397004753	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
585397004754	NlpC/P60 family; Region: NLPC_P60; cl17555
585397004755	Prophage antirepressor [Transcription]; Region: COG3617
585397004756	BRO family, N-terminal domain; Region: Bro-N; smart01040
585397004757	Phage anti-repressor protein [Transcription]; Region: COG3561
585397004758	putative regulatory protein from phage origin (partial match);Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7999761, 10426954; Product type pr : putative regulator
585397004759	Mnt; Region: mnt; PHA01513
585397004760	Arc-like DNA binding domain; Region: Arc; pfam03869
585397004761	Caseinolytic protease (ClpP) is an ATP-dependent protease; Region: Clp_protease_like; cl15763
585397004762	active site
585397004763	Phage-related protein [Function unknown]; Region: gp18; COG4672
585397004764	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
585397004765	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
585397004766	trimer interface [polypeptide binding]; other site
585397004767	eyelet of channel; other site
585397004768	Phage-related protein [Function unknown]; Region: COG4718
585397004769	Phage-related minor tail protein [Function unknown]; Region: COG5281
585397004770	tape measure domain; Region: tape_meas_nterm; TIGR02675
585397004771	Tail length tape measure protein; Region: Phage_HK97_TLTM; pfam06120
585397004772	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
585397004773	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
585397004774	Protein of unknown function (DUF4035); Region: DUF4035; pfam13227
585397004775	Phage tail assembly chaperone; Region: Phage_TAC; pfam06222
585397004776	Immunoglobulin domain; Region: Ig; cd00096
585397004777	Protein of unknown function (DUF3168); Region: DUF3168; pfam11367
585397004778	phage protein, HK97 gp10 family; Region: phge_HK97_gp10; TIGR01725
585397004779	Bacteriophage head-tail adaptor [General function prediction only]; Region: COG5614
585397004780	Carbohydrate binding domain; Region: CBM_5_12; pfam02839
585397004781	Phage-related protein [Function unknown]; Region: COG4695
585397004782	phage portal protein, HK97 family; Region: portal_HK97; TIGR01537
585397004783	Caudovirus prohead protease; Region: Peptidase_U35; pfam04586
585397004784	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
585397004785	Phage capsid family; Region: Phage_capsid; pfam05065
585397004786	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
585397004787	Phage terminase, small subunit [DNA replication, recombination, and repair]; Region: XtmA; COG3728
585397004788	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
585397004789	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
585397004790	active site
585397004791	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
585397004792	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
585397004793	KilA-N domain; Region: KilA-N; pfam04383
585397004794	ORF11CD3 domain; Region: ORF11CD3; pfam10549
585397004795	Protein of unknown function (DUF3423); Region: DUF3423; pfam11903
585397004796	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
585397004797	Uncharacterized phage-encoded protein [Function unknown]; Region: COG3645
585397004798	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
585397004799	catalytic residues [active]
585397004800	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
585397004801	Lysis protein S; Region: Lysis_S; pfam04971
585397004802	Protein of unknown function (DUF826); Region: DUF826; pfam05696
585397004803	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
585397004804	Domain of unknown function (DUF303); Region: DUF303; pfam03629
585397004805	Phage antitermination protein Q; Region: Phage_antiter_Q; pfam06323
585397004806	Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570
585397004807	Protein of unknown function (DUF968); Region: DUF968; pfam06147
585397004808	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1636
585397004809	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
585397004810	Protein of unknown function (DUF1627); Region: DUF1627; pfam07789
585397004811	primosomal protein DnaI; Provisional; Region: PRK02854
585397004812	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
585397004813	Uncharacterized protein conserved in bacteria, prophage-related [Function unknown]; Region: COG4197
585397004814	transcriptional repressor DicA; Reviewed; Region: PRK09706
585397004815	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
585397004816	DicB protein; Region: DicB; pfam05358
585397004817	exonuclease VIII; Reviewed; Region: PRK09709
585397004818	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
585397004819	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
585397004820	active site
585397004821	substrate binding site [chemical binding]; other site
585397004822	catalytic site [active]
585397004823	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
585397004824	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
585397004825	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
585397004826	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
585397004827	Int/Topo IB signature motif; other site
585397004828	putative oxidoreductase; Provisional; Region: PRK10083
585397004829	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
585397004830	putative NAD(P) binding site [chemical binding]; other site
585397004831	catalytic Zn binding site [ion binding]; other site
585397004832	structural Zn binding site [ion binding]; other site
585397004833	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
585397004834	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
585397004835	putative active site pocket [active]
585397004836	putative metal binding site [ion binding]; other site
585397004837	hypothetical protein; Provisional; Region: PRK02237
585397004838	hypothetical protein; Provisional; Region: PRK13659
585397004839	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
585397004840	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585397004841	Coenzyme A binding pocket [chemical binding]; other site
585397004842	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
585397004843	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
585397004844	fragment of oxidoreductase subunit (part 1);Evidence 7 : Gene remnant; Product type e : enzyme
585397004845	fragment of oxidoreductase subunit (part 2);Evidence 7 : Gene remnant; Product type e : enzyme
585397004846	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
585397004847	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
585397004848	putative [Fe4-S4] binding site [ion binding]; other site
585397004849	putative molybdopterin cofactor binding site [chemical binding]; other site
585397004850	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
585397004851	putative molybdopterin cofactor binding site; other site
585397004852	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
585397004853	4Fe-4S binding domain; Region: Fer4; cl02805
585397004854	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
585397004855	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
585397004856	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
585397004857	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
585397004858	Cl- selectivity filter; other site
585397004859	Cl- binding residues [ion binding]; other site
585397004860	pore gating glutamate residue; other site
585397004861	dimer interface [polypeptide binding]; other site
585397004862	putative dithiobiotin synthetase; Provisional; Region: PRK12374
585397004863	AAA domain; Region: AAA_26; pfam13500
585397004864	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
585397004865	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
585397004866	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
585397004867	nucleotide binding site [chemical binding]; other site
585397004868	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
585397004869	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397004870	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
585397004871	dimerization interface [polypeptide binding]; other site
585397004872	substrate binding pocket [chemical binding]; other site
585397004873	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
585397004874	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397004875	putative substrate translocation pore; other site
585397004876	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
585397004877	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
585397004878	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
585397004879	fragment of conserved hypothetical protein; putative inner membrane protein (partial);Evidence 7 : Gene remnant; Product type pm : putative membrane component
585397004880	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
585397004881	Phage terminase, small subunit [DNA replication, recombination, and repair]; Region: COG3747
585397004882	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
585397004883	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
585397004884	active site
585397004885	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
585397004886	oligomerization interface [polypeptide binding]; other site
585397004887	Phage-related protein [Function unknown]; Region: COG4695
585397004888	Phage portal protein; Region: Phage_portal; pfam04860
585397004889	Phage head maturation protease [General function prediction only]; Region: COG3740
585397004890	Predicted phage phi-C31 gp36 major capsid-like protein [General function prediction only]; Region: COG4653
585397004891	Phage capsid family; Region: Phage_capsid; pfam05065
585397004892	PerC transcriptional activator; Region: PerC; pfam06069
585397004893	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
585397004894	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
585397004895	ssDNA binding site [nucleotide binding]; other site
585397004896	dimer interface [polypeptide binding]; other site
585397004897	tetramer (dimer of dimers) interface [polypeptide binding]; other site
585397004898	D5 N terminal like; Region: D5_N; smart00885
585397004899	Phage associated DNA primase [General function prediction only]; Region: COG3378
585397004900	Poxvirus D5 protein-like; Region: Pox_D5; pfam03288
585397004901	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
585397004902	putative lcd-like protein from phage origin;Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8491703; Product type h : extrachromosomal origin
585397004903	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
585397004904	integrase; Provisional; Region: PRK09692
585397004905	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
585397004906	active site
585397004907	Int/Topo IB signature motif; other site
585397004908	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
585397004909	Domain of unknown function DUF20; Region: UPF0118; pfam01594
585397004910	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
585397004911	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
585397004912	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
585397004913	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
585397004914	ligand binding site [chemical binding]; other site
585397004915	homodimer interface [polypeptide binding]; other site
585397004916	NAD(P) binding site [chemical binding]; other site
585397004917	trimer interface B [polypeptide binding]; other site
585397004918	trimer interface A [polypeptide binding]; other site
585397004919	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
585397004920	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
585397004921	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
585397004922	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
585397004923	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
585397004924	Spore germination protein; Region: Spore_permease; cl17796
585397004925	dihydromonapterin reductase; Provisional; Region: PRK06483
585397004926	pteridine reductase (PR), classical (c) SDRs; Region: PR_SDR_c; cd05357
585397004927	NADP binding site [chemical binding]; other site
585397004928	substrate binding pocket [chemical binding]; other site
585397004929	active site
585397004930	GlpM protein; Region: GlpM; pfam06942
585397004931	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
585397004932	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397004933	active site
585397004934	phosphorylation site [posttranslational modification]
585397004935	intermolecular recognition site; other site
585397004936	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585397004937	DNA binding site [nucleotide binding]
585397004938	sensor protein RstB; Provisional; Region: PRK10604
585397004939	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585397004940	dimerization interface [polypeptide binding]; other site
585397004941	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585397004942	dimer interface [polypeptide binding]; other site
585397004943	phosphorylation site [posttranslational modification]
585397004944	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397004945	ATP binding site [chemical binding]; other site
585397004946	Mg2+ binding site [ion binding]; other site
585397004947	G-X-G motif; other site
585397004948	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
585397004949	fumarate hydratase; Reviewed; Region: fumC; PRK00485
585397004950	Class II fumarases; Region: Fumarase_classII; cd01362
585397004951	active site
585397004952	tetramer interface [polypeptide binding]; other site
585397004953	fumarate hydratase; Provisional; Region: PRK15389
585397004954	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
585397004955	Fumarase C-terminus; Region: Fumerase_C; pfam05683
585397004956	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
585397004957	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
585397004958	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
585397004959	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
585397004960	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
585397004961	putative outer membrane porin protein; Provisional; Region: PRK11379
585397004962	glucuronide transporter; Provisional; Region: PRK09848
585397004963	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
585397004964	beta-D-glucuronidase; Provisional; Region: PRK10150
585397004965	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
585397004966	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
585397004967	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
585397004968	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
585397004969	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585397004970	7-alpha-hydroxysteroid dehydrogenase; Validated; Region: PRK06113
585397004971	7 alpha-hydroxysteroid dehydrogenase (7 alpha-HSDH), classical (c) SDRs; Region: 7_alpha_HSDH_SDR_c; cd05365
585397004972	NAD binding site [chemical binding]; other site
585397004973	substrate binding site [chemical binding]; other site
585397004974	homotetramer interface [polypeptide binding]; other site
585397004975	homodimer interface [polypeptide binding]; other site
585397004976	active site
585397004977	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
585397004978	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585397004979	DNA binding site [nucleotide binding]
585397004980	domain linker motif; other site
585397004981	Ligand-binding domain of MalI, a transcription regulator of the maltose system of Escherichia coli and its close homologs from other bacteria; Region: PBP1_MalI_like; cd06289
585397004982	putative dimerization interface [polypeptide binding]; other site
585397004983	putative ligand binding site [chemical binding]; other site
585397004984	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
585397004985	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
585397004986	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
585397004987	active site turn [active]
585397004988	phosphorylation site [posttranslational modification]
585397004989	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
585397004990	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585397004991	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397004992	homodimer interface [polypeptide binding]; other site
585397004993	catalytic residue [active]
585397004994	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
585397004995	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
585397004996	active site
585397004997	purine riboside binding site [chemical binding]; other site
585397004998	putative oxidoreductase; Provisional; Region: PRK11579
585397004999	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
585397005000	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
585397005001	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
585397005002	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
585397005003	electron transport complex protein RsxA; Provisional; Region: PRK05151
585397005004	electron transport complex protein RnfB; Provisional; Region: PRK05113
585397005005	Putative Fe-S cluster; Region: FeS; pfam04060
585397005006	4Fe-4S binding domain; Region: Fer4; pfam00037
585397005007	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
585397005008	SLBB domain; Region: SLBB; pfam10531
585397005009	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
585397005010	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
585397005011	electron transport complex protein RnfG; Validated; Region: PRK01908
585397005012	electron transport complex RsxE subunit; Provisional; Region: PRK12405
585397005013	endonuclease III; Provisional; Region: PRK10702
585397005014	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
585397005015	minor groove reading motif; other site
585397005016	helix-hairpin-helix signature motif; other site
585397005017	substrate binding pocket [chemical binding]; other site
585397005018	active site
585397005019	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
585397005020	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
585397005021	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397005022	putative substrate translocation pore; other site
585397005023	POT family; Region: PTR2; pfam00854
585397005024	glutathionine S-transferase; Provisional; Region: PRK10542
585397005025	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
585397005026	C-terminal domain interface [polypeptide binding]; other site
585397005027	GSH binding site (G-site) [chemical binding]; other site
585397005028	dimer interface [polypeptide binding]; other site
585397005029	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
585397005030	N-terminal domain interface [polypeptide binding]; other site
585397005031	dimer interface [polypeptide binding]; other site
585397005032	substrate binding pocket (H-site) [chemical binding]; other site
585397005033	pyridoxamine kinase; Validated; Region: PRK05756
585397005034	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
585397005035	dimer interface [polypeptide binding]; other site
585397005036	pyridoxal binding site [chemical binding]; other site
585397005037	ATP binding site [chemical binding]; other site
585397005038	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
585397005039	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
585397005040	active site
585397005041	HIGH motif; other site
585397005042	dimer interface [polypeptide binding]; other site
585397005043	KMSKS motif; other site
585397005044	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
585397005045	RNA binding surface [nucleotide binding]; other site
585397005046	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
585397005047	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
585397005048	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
585397005049	lysozyme inhibitor; Provisional; Region: PRK11372
585397005050	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
585397005051	Uncharacterized protein family (UPF0075); Region: UPF0075; pfam03702
585397005052	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
585397005053	transcriptional regulator SlyA; Provisional; Region: PRK03573
585397005054	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
585397005055	Protein of unknown function (DUF1656); Region: DUF1656; cl11658
585397005056	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
585397005057	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585397005058	HlyD family secretion protein; Region: HlyD_3; pfam13437
585397005059	Fusaric acid resistance protein family; Region: FUSC; pfam04632
585397005060	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
585397005061	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
585397005062	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
585397005063	E-class dimer interface [polypeptide binding]; other site
585397005064	P-class dimer interface [polypeptide binding]; other site
585397005065	active site
585397005066	Cu2+ binding site [ion binding]; other site
585397005067	Zn2+ binding site [ion binding]; other site
585397005068	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
585397005069	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
585397005070	active site
585397005071	catalytic tetrad [active]
585397005072	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
585397005073	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585397005074	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
585397005075	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
585397005076	FMN binding site [chemical binding]; other site
585397005077	active site
585397005078	substrate binding site [chemical binding]; other site
585397005079	catalytic residue [active]
585397005080	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
585397005081	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
585397005082	dimer interface [polypeptide binding]; other site
585397005083	active site
585397005084	metal binding site [ion binding]; metal-binding site
585397005085	glutathione binding site [chemical binding]; other site
585397005086	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
585397005087	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
585397005088	dimer interface [polypeptide binding]; other site
585397005089	catalytic site [active]
585397005090	putative active site [active]
585397005091	putative substrate binding site [chemical binding]; other site
585397005092	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
585397005093	putative GSH binding site [chemical binding]; other site
585397005094	catalytic residues [active]
585397005095	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
585397005096	NlpC/P60 family; Region: NLPC_P60; pfam00877
585397005097	superoxide dismutase; Provisional; Region: PRK10543
585397005098	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
585397005099	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
585397005100	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
585397005101	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397005102	putative substrate translocation pore; other site
585397005103	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
585397005104	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585397005105	DNA binding site [nucleotide binding]
585397005106	domain linker motif; other site
585397005107	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
585397005108	dimerization interface [polypeptide binding]; other site
585397005109	ligand binding site [chemical binding]; other site
585397005110	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
585397005111	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397005112	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
585397005113	dimerization interface [polypeptide binding]; other site
585397005114	putative transporter; Provisional; Region: PRK11043
585397005115	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397005116	putative substrate translocation pore; other site
585397005117	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
585397005118	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
585397005119	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397005120	S-adenosylmethionine binding site [chemical binding]; other site
585397005121	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
585397005122	Lumazine binding domain; Region: Lum_binding; pfam00677
585397005123	Lumazine binding domain; Region: Lum_binding; pfam00677
585397005124	multidrug efflux protein; Reviewed; Region: PRK01766
585397005125	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
585397005126	cation binding site [ion binding]; other site
585397005127	hypothetical protein; Provisional; Region: PRK09945
585397005128	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
585397005129	putative monooxygenase; Provisional; Region: PRK11118
585397005130	hypothetical protein; Provisional; Region: PRK09897
585397005131	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
585397005132	hypothetical protein; Provisional; Region: PRK09946
585397005133	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
585397005134	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
585397005135	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
585397005136	hypothetical protein; Provisional; Region: PRK09947
585397005137	fragment of putative ferredoxin:oxidoreductase subunit (part 2);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397005138	fragment of putative ferredoxin:oxidoreductase subunit (part 1);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397005139	hypothetical protein; Provisional; Region: PRK09898
585397005140	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
585397005141	hypothetical protein; Provisional; Region: PRK10292
585397005142	pyruvate kinase; Provisional; Region: PRK09206
585397005143	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
585397005144	domain interfaces; other site
585397005145	active site
585397005146	murein lipoprotein; Provisional; Region: PRK15396
585397005147	L,D-transpeptidase; Provisional; Region: PRK10190
585397005148	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
585397005149	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
585397005150	cysteine desufuration protein SufE; Provisional; Region: PRK09296
585397005151	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
585397005152	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
585397005153	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
585397005154	catalytic residue [active]
585397005155	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
585397005156	FeS assembly protein SufD; Region: sufD; TIGR01981
585397005157	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
585397005158	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
585397005159	Walker A/P-loop; other site
585397005160	ATP binding site [chemical binding]; other site
585397005161	Q-loop/lid; other site
585397005162	ABC transporter signature motif; other site
585397005163	Walker B; other site
585397005164	D-loop; other site
585397005165	H-loop/switch region; other site
585397005166	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
585397005167	putative ABC transporter; Region: ycf24; CHL00085
585397005168	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
585397005169	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
585397005170	CoenzymeA binding site [chemical binding]; other site
585397005171	subunit interaction site [polypeptide binding]; other site
585397005172	PHB binding site; other site
585397005173	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
585397005174	FAD binding domain; Region: FAD_binding_4; pfam01565
585397005175	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
585397005176	putative inner membrane protein; Provisional; Region: PRK10983
585397005177	Domain of unknown function DUF20; Region: UPF0118; pfam01594
585397005178	Domain of unknown function (DUF1870); Region: DUF1870; pfam08965
585397005179	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397005180	Major Facilitator Superfamily; Region: MFS_1; pfam07690
585397005181	putative substrate translocation pore; other site
585397005182	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397005183	putative substrate translocation pore; other site
585397005184	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
585397005185	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
585397005186	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
585397005187	shikimate binding site; other site
585397005188	NAD(P) binding site [chemical binding]; other site
585397005189	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
585397005190	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
585397005191	active site
585397005192	catalytic residue [active]
585397005193	dimer interface [polypeptide binding]; other site
585397005194	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
585397005195	Coenzyme A transferase; Region: CoA_trans; smart00882
585397005196	Coenzyme A transferase; Region: CoA_trans; cl17247
585397005197	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
585397005198	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397005199	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397005200	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397005201	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
585397005202	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
585397005203	active site
585397005204	Cupin domain; Region: Cupin_2; pfam07883
585397005205	Winged helix DNA-binding domain (DUF1495); Region: DUF1495; cl01336
585397005206	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
585397005207	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397005208	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
585397005209	Ligand binding site [chemical binding]; other site
585397005210	Electron transfer flavoprotein domain; Region: ETF; pfam01012
585397005211	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
585397005212	Electron transfer flavoprotein domain; Region: ETF; smart00893
585397005213	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
585397005214	oxidoreductase; Provisional; Region: PRK10015
585397005215	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
585397005216	short chain acyl-CoA synthetase; Reviewed; Region: PRK06087
585397005217	Cyclohexanecarboxylate-CoA ligase (also called cyclohex-1-ene-1-carboxylate:CoA ligase); Region: CHC_CoA_lg; cd05903
585397005218	acyl-activating enzyme (AAE) consensus motif; other site
585397005219	putative AMP binding site [chemical binding]; other site
585397005220	putative active site [active]
585397005221	putative CoA binding site [chemical binding]; other site
585397005222	phosphoenolpyruvate synthase; Validated; Region: PRK06464
585397005223	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
585397005224	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
585397005225	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
585397005226	PEP synthetase regulatory protein; Provisional; Region: PRK05339
585397005227	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
585397005228	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
585397005229	Hemin uptake protein [Inorganic ion transport and metabolism]; Region: HemP; COG4256
585397005230	Uncharacterized conserved protein [Function unknown]; Region: COG0397
585397005231	hypothetical protein; Validated; Region: PRK00029
585397005232	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
585397005233	NlpC/P60 family; Region: NLPC_P60; pfam00877
585397005234	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
585397005235	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
585397005236	Walker A/P-loop; other site
585397005237	ATP binding site [chemical binding]; other site
585397005238	Q-loop/lid; other site
585397005239	ABC transporter signature motif; other site
585397005240	Walker B; other site
585397005241	D-loop; other site
585397005242	H-loop/switch region; other site
585397005243	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
585397005244	catalytic residues [active]
585397005245	dimer interface [polypeptide binding]; other site
585397005246	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
585397005247	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
585397005248	ABC-ATPase subunit  interface; other site
585397005249	dimer interface [polypeptide binding]; other site
585397005250	putative PBP binding regions; other site
585397005251	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
585397005252	IHF dimer interface [polypeptide binding]; other site
585397005253	IHF - DNA interface [nucleotide binding]; other site
585397005254	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
585397005255	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
585397005256	putative tRNA-binding site [nucleotide binding]; other site
585397005257	B3/4 domain; Region: B3_4; pfam03483
585397005258	tRNA synthetase B5 domain; Region: B5; smart00874
585397005259	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
585397005260	dimer interface [polypeptide binding]; other site
585397005261	motif 1; other site
585397005262	motif 3; other site
585397005263	motif 2; other site
585397005264	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
585397005265	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
585397005266	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
585397005267	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
585397005268	dimer interface [polypeptide binding]; other site
585397005269	motif 1; other site
585397005270	active site
585397005271	motif 2; other site
585397005272	motif 3; other site
585397005273	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
585397005274	23S rRNA binding site [nucleotide binding]; other site
585397005275	L21 binding site [polypeptide binding]; other site
585397005276	L13 binding site [polypeptide binding]; other site
585397005277	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
585397005278	fragment of protein chain initiation factor IF-3 (partial);Evidence 7 : Gene remnant; Product type f : factor
585397005279	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
585397005280	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
585397005281	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
585397005282	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
585397005283	active site
585397005284	dimer interface [polypeptide binding]; other site
585397005285	motif 1; other site
585397005286	motif 2; other site
585397005287	motif 3; other site
585397005288	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
585397005289	anticodon binding site; other site
585397005290	fragment of putative ankyrin repeat regulatory protein (part 1);Evidence 7 : Gene remnant; Product type pr : putative regulator
585397005291	fragment of putative ankyrin repeat regulatory protein (part 2);Evidence 7 : Gene remnant; Product type pr : putative regulator
585397005292	fragment of putative ankyrin repeat regulatory protein (part 3);Evidence 7 : Gene remnant; Product type pr : putative regulator
585397005293	fragment of putative ankyrin repeat regulatory protein (part 4);Evidence 7 : Gene remnant; Product type pr : putative regulator
585397005294	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
585397005295	6-phosphofructokinase 2; Provisional; Region: PRK10294
585397005296	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
585397005297	putative substrate binding site [chemical binding]; other site
585397005298	putative ATP binding site [chemical binding]; other site
585397005299	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
585397005300	Phosphotransferase enzyme family; Region: APH; pfam01636
585397005301	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
585397005302	active site
585397005303	ATP binding site [chemical binding]; other site
585397005304	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
585397005305	YniB-like protein; Region: YniB; pfam14002
585397005306	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
585397005307	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
585397005308	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397005309	motif II; other site
585397005310	inner membrane protein; Provisional; Region: PRK11648
585397005311	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
585397005312	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
585397005313	cell division modulator; Provisional; Region: PRK10113
585397005314	hydroperoxidase II; Provisional; Region: katE; PRK11249
585397005315	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
585397005316	tetramer interface [polypeptide binding]; other site
585397005317	heme binding pocket [chemical binding]; other site
585397005318	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
585397005319	domain interactions; other site
585397005320	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
585397005321	putative active site [active]
585397005322	YdjC motif; other site
585397005323	Mg binding site [ion binding]; other site
585397005324	putative homodimer interface [polypeptide binding]; other site
585397005325	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
585397005326	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
585397005327	NAD binding site [chemical binding]; other site
585397005328	sugar binding site [chemical binding]; other site
585397005329	divalent metal binding site [ion binding]; other site
585397005330	tetramer (dimer of dimers) interface [polypeptide binding]; other site
585397005331	dimer interface [polypeptide binding]; other site
585397005332	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
585397005333	Cupin domain; Region: Cupin_2; pfam07883
585397005334	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397005335	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
585397005336	methionine cluster; other site
585397005337	active site
585397005338	phosphorylation site [posttranslational modification]
585397005339	metal binding site [ion binding]; metal-binding site
585397005340	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
585397005341	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
585397005342	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
585397005343	active site
585397005344	P-loop; other site
585397005345	phosphorylation site [posttranslational modification]
585397005346	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
585397005347	NAD+ synthetase; Region: nadE; TIGR00552
585397005348	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
585397005349	homodimer interface [polypeptide binding]; other site
585397005350	NAD binding pocket [chemical binding]; other site
585397005351	ATP binding pocket [chemical binding]; other site
585397005352	Mg binding site [ion binding]; other site
585397005353	active-site loop [active]
585397005354	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
585397005355	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
585397005356	GIY-YIG motif/motif A; other site
585397005357	active site
585397005358	catalytic site [active]
585397005359	putative DNA binding site [nucleotide binding]; other site
585397005360	metal binding site [ion binding]; metal-binding site
585397005361	hypothetical protein; Provisional; Region: PRK11396
585397005362	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
585397005363	dimer interface [polypeptide binding]; other site
585397005364	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
585397005365	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
585397005366	putative active site [active]
585397005367	Zn binding site [ion binding]; other site
585397005368	succinylarginine dihydrolase; Provisional; Region: PRK13281
585397005369	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
585397005370	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
585397005371	NAD(P) binding site [chemical binding]; other site
585397005372	catalytic residues [active]
585397005373	arginine succinyltransferase; Provisional; Region: PRK10456
585397005374	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
585397005375	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
585397005376	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
585397005377	inhibitor-cofactor binding pocket; inhibition site
585397005378	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397005379	catalytic residue [active]
585397005380	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
585397005381	putative catalytic site [active]
585397005382	putative phosphate binding site [ion binding]; other site
585397005383	active site
585397005384	metal binding site A [ion binding]; metal-binding site
585397005385	DNA binding site [nucleotide binding]
585397005386	putative AP binding site [nucleotide binding]; other site
585397005387	putative metal binding site B [ion binding]; other site
585397005388	Uncharacterized conserved protein [Function unknown]; Region: COG0398
585397005389	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
585397005390	Uncharacterized conserved protein [Function unknown]; Region: COG0398
585397005391	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
585397005392	Uncharacterized conserved protein [Function unknown]; Region: COG2128
585397005393	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
585397005394	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4134
585397005395	hypothetical protein; Provisional; Region: PRK11622
585397005396	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4135
585397005397	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397005398	dimer interface [polypeptide binding]; other site
585397005399	conserved gate region; other site
585397005400	putative PBP binding loops; other site
585397005401	ABC-ATPase subunit interface; other site
585397005402	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4136
585397005403	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397005404	Walker A/P-loop; other site
585397005405	ATP binding site [chemical binding]; other site
585397005406	Q-loop/lid; other site
585397005407	ABC transporter signature motif; other site
585397005408	Walker B; other site
585397005409	D-loop; other site
585397005410	H-loop/switch region; other site
585397005411	Rhodanese Homology Domain; Region: RHOD; smart00450
585397005412	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
585397005413	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
585397005414	active site residue [active]
585397005415	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
585397005416	active site residue [active]
585397005417	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
585397005418	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
585397005419	active site
585397005420	8-oxo-dGMP binding site [chemical binding]; other site
585397005421	nudix motif; other site
585397005422	metal binding site [ion binding]; metal-binding site
585397005423	glutamate dehydrogenase; Provisional; Region: PRK09414
585397005424	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
585397005425	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
585397005426	NAD(P) binding site [chemical binding]; other site
585397005427	DNA topoisomerase III; Provisional; Region: PRK07726
585397005428	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
585397005429	active site
585397005430	putative interdomain interaction site [polypeptide binding]; other site
585397005431	putative metal-binding site [ion binding]; other site
585397005432	putative nucleotide binding site [chemical binding]; other site
585397005433	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
585397005434	domain I; other site
585397005435	DNA binding groove [nucleotide binding]
585397005436	phosphate binding site [ion binding]; other site
585397005437	domain II; other site
585397005438	domain III; other site
585397005439	nucleotide binding site [chemical binding]; other site
585397005440	catalytic site [active]
585397005441	domain IV; other site
585397005442	selenophosphate synthetase; Provisional; Region: PRK00943
585397005443	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
585397005444	dimerization interface [polypeptide binding]; other site
585397005445	putative ATP binding site [chemical binding]; other site
585397005446	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
585397005447	putative FMN binding site [chemical binding]; other site
585397005448	protease 4; Provisional; Region: PRK10949
585397005449	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
585397005450	tandem repeat interface [polypeptide binding]; other site
585397005451	oligomer interface [polypeptide binding]; other site
585397005452	active site residues [active]
585397005453	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
585397005454	tandem repeat interface [polypeptide binding]; other site
585397005455	oligomer interface [polypeptide binding]; other site
585397005456	active site residues [active]
585397005457	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
585397005458	active site
585397005459	homodimer interface [polypeptide binding]; other site
585397005460	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
585397005461	Isochorismatase family; Region: Isochorismatase; pfam00857
585397005462	catalytic triad [active]
585397005463	metal binding site [ion binding]; metal-binding site
585397005464	conserved cis-peptide bond; other site
585397005465	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
585397005466	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397005467	putative substrate translocation pore; other site
585397005468	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397005469	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
585397005470	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
585397005471	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585397005472	fragment of putative oxidoreductase; similar to aldo/keto reductase (part 2);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397005473	fragment of putative oxidoreductase; similar to aldo/keto reductase (part 1);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397005474	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
585397005475	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
585397005476	substrate binding site [chemical binding]; other site
585397005477	ATP binding site [chemical binding]; other site
585397005478	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
585397005479	intersubunit interface [polypeptide binding]; other site
585397005480	active site
585397005481	zinc binding site [ion binding]; other site
585397005482	Na+ binding site [ion binding]; other site
585397005483	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
585397005484	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
585397005485	inhibitor binding site; inhibition site
585397005486	catalytic Zn binding site [ion binding]; other site
585397005487	structural Zn binding site [ion binding]; other site
585397005488	NADP binding site [chemical binding]; other site
585397005489	tetramer interface [polypeptide binding]; other site
585397005490	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397005491	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397005492	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
585397005493	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH4; cd08258
585397005494	putative NAD(P) binding site [chemical binding]; other site
585397005495	catalytic Zn binding site [ion binding]; other site
585397005496	structural Zn binding site [ion binding]; other site
585397005497	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
585397005498	methionine sulfoxide reductase B; Provisional; Region: PRK00222
585397005499	SelR domain; Region: SelR; pfam01641
585397005500	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
585397005501	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
585397005502	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
585397005503	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
585397005504	active site
585397005505	phosphate binding residues; other site
585397005506	catalytic residues [active]
585397005507	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
585397005508	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
585397005509	active site
585397005510	catalytic tetrad [active]
585397005511	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
585397005512	PrkA family serine protein kinase; Provisional; Region: PRK15455
585397005513	AAA ATPase domain; Region: AAA_16; pfam13191
585397005514	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
585397005515	hypothetical protein; Provisional; Region: PRK05325
585397005516	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
585397005517	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585397005518	metal binding site [ion binding]; metal-binding site
585397005519	active site
585397005520	I-site; other site
585397005521	putative diguanylate cyclase (part 1);Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
585397005522	fragment of putative diguanylate cyclase (partial);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397005523	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
585397005524	putative deacylase active site [active]
585397005525	Predicted membrane protein [Function unknown]; Region: COG2707
585397005526	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
585397005527	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397005528	cyanate transporter; Region: CynX; TIGR00896
585397005529	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397005530	Uncharacterized conserved protein [Function unknown]; Region: COG3189
585397005531	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
585397005532	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
585397005533	Domain of unknown function (DUF333); Region: DUF333; pfam03891
585397005534	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
585397005535	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
585397005536	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
585397005537	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585397005538	metal binding site [ion binding]; metal-binding site
585397005539	active site
585397005540	I-site; other site
585397005541	hypothetical protein; Provisional; Region: PRK10457
585397005542	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
585397005543	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
585397005544	leucine export protein LeuE; Provisional; Region: PRK10958
585397005545	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
585397005546	fragment of putative tartrate dehydrogenase (partial);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397005547	ribonuclease D; Provisional; Region: PRK10829
585397005548	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
585397005549	catalytic site [active]
585397005550	putative active site [active]
585397005551	putative substrate binding site [chemical binding]; other site
585397005552	Helicase and RNase D C-terminal; Region: HRDC; smart00341
585397005553	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
585397005554	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
585397005555	acyl-activating enzyme (AAE) consensus motif; other site
585397005556	putative AMP binding site [chemical binding]; other site
585397005557	putative active site [active]
585397005558	putative CoA binding site [chemical binding]; other site
585397005559	Outer membrane lipoprotein Slp family; Region: Slp; cl01164
585397005560	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
585397005561	Glycoprotease family; Region: Peptidase_M22; pfam00814
585397005562	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
585397005563	DEAD/DEAH box helicase; Region: DEAD; pfam00270
585397005564	DEAD_2; Region: DEAD_2; pfam06733
585397005565	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
585397005566	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
585397005567	homotrimer interaction site [polypeptide binding]; other site
585397005568	putative active site [active]
585397005569	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
585397005570	hypothetical protein; Provisional; Region: PRK05114
585397005571	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
585397005572	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
585397005573	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
585397005574	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
585397005575	putative active site [active]
585397005576	putative CoA binding site [chemical binding]; other site
585397005577	nudix motif; other site
585397005578	metal binding site [ion binding]; metal-binding site
585397005579	L-serine deaminase; Provisional; Region: PRK15023
585397005580	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
585397005581	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
585397005582	phage resistance protein; Provisional; Region: PRK10551
585397005583	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
585397005584	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585397005585	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
585397005586	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
585397005587	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
585397005588	Transporter associated domain; Region: CorC_HlyC; smart01091
585397005589	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
585397005590	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
585397005591	active pocket/dimerization site; other site
585397005592	active site
585397005593	phosphorylation site [posttranslational modification]
585397005594	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
585397005595	active site
585397005596	phosphorylation site [posttranslational modification]
585397005597	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
585397005598	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
585397005599	Predicted membrane protein [Function unknown]; Region: COG4811
585397005600	hypothetical protein; Provisional; Region: PRK11469
585397005601	Domain of unknown function DUF; Region: DUF204; pfam02659
585397005602	Domain of unknown function DUF; Region: DUF204; pfam02659
585397005603	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
585397005604	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397005605	S-adenosylmethionine binding site [chemical binding]; other site
585397005606	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
585397005607	DNA-binding site [nucleotide binding]; DNA binding site
585397005608	RNA-binding motif; other site
585397005609	Protein of unknown function (DUF2627); Region: DUF2527; pfam10736
585397005610	YebO-like protein; Region: YebO; pfam13974
585397005611	PhoPQ regulatory protein; Provisional; Region: PRK10299
585397005612	YobH-like protein; Region: YobH; pfam13996
585397005613	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
585397005614	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
585397005615	dimerization interface [polypeptide binding]; other site
585397005616	putative Zn2+ binding site [ion binding]; other site
585397005617	putative DNA binding site [nucleotide binding]; other site
585397005618	Bacterial transcriptional regulator; Region: IclR; pfam01614
585397005619	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397005620	Major Facilitator Superfamily; Region: MFS_1; pfam07690
585397005621	putative substrate translocation pore; other site
585397005622	Predicted integral membrane protein [Function unknown]; Region: COG5521
585397005623	heat shock protein HtpX; Provisional; Region: PRK05457
585397005624	carboxy-terminal protease; Provisional; Region: PRK11186
585397005625	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
585397005626	protein binding site [polypeptide binding]; other site
585397005627	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
585397005628	Catalytic dyad [active]
585397005629	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
585397005630	ProP expression regulator; Provisional; Region: PRK04950
585397005631	ProQ/FINO family; Region: ProQ; pfam04352
585397005632	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
585397005633	GAF domain; Region: GAF_2; pfam13185
585397005634	integral membrane protein, PqiA family; Region: pqiA_fam; TIGR00155
585397005635	Paraquat-inducible protein A; Region: PqiA; pfam04403
585397005636	Paraquat-inducible protein A; Region: PqiA; pfam04403
585397005637	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
585397005638	mce related protein; Region: MCE; pfam02470
585397005639	mce related protein; Region: MCE; pfam02470
585397005640	mce related protein; Region: MCE; pfam02470
585397005641	mce related protein; Region: MCE; pfam02470
585397005642	mce related protein; Region: MCE; pfam02470
585397005643	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
585397005644	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397005645	S-adenosylmethionine binding site [chemical binding]; other site
585397005646	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
585397005647	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
585397005648	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
585397005649	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
585397005650	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
585397005651	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
585397005652	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
585397005653	hypothetical protein; Provisional; Region: PRK10301
585397005654	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
585397005655	Predicted amidohydrolase [General function prediction only]; Region: COG0388
585397005656	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
585397005657	exodeoxyribonuclease X; Provisional; Region: PRK07983
585397005658	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
585397005659	active site
585397005660	catalytic site [active]
585397005661	substrate binding site [chemical binding]; other site
585397005662	protease 2; Provisional; Region: PRK10115
585397005663	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
585397005664	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
585397005665	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
585397005666	putative metal binding site [ion binding]; other site
585397005667	hypothetical protein; Provisional; Region: PRK13680
585397005668	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
585397005669	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
585397005670	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
585397005671	ATP-grasp domain; Region: ATP-grasp; pfam02222
585397005672	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
585397005673	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
585397005674	active site
585397005675	intersubunit interface [polypeptide binding]; other site
585397005676	catalytic residue [active]
585397005677	phosphogluconate dehydratase; Validated; Region: PRK09054
585397005678	6-phosphogluconate dehydratase; Region: edd; TIGR01196
585397005679	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
585397005680	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
585397005681	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
585397005682	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
585397005683	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
585397005684	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
585397005685	putative active site [active]
585397005686	pyruvate kinase; Provisional; Region: PRK05826
585397005687	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
585397005688	domain interfaces; other site
585397005689	active site
585397005690	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
585397005691	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
585397005692	putative acyl-acceptor binding pocket; other site
585397005693	putative peptidase; Provisional; Region: PRK11649
585397005694	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
585397005695	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
585397005696	Peptidase family M23; Region: Peptidase_M23; pfam01551
585397005697	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
585397005698	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
585397005699	metal binding site [ion binding]; metal-binding site
585397005700	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
585397005701	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
585397005702	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
585397005703	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
585397005704	ABC-ATPase subunit  interface; other site
585397005705	dimer interface [polypeptide binding]; other site
585397005706	putative PBP binding regions; other site
585397005707	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
585397005708	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397005709	Walker A motif; other site
585397005710	ATP binding site [chemical binding]; other site
585397005711	Walker B motif; other site
585397005712	arginine finger; other site
585397005713	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
585397005714	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
585397005715	RuvA N terminal domain; Region: RuvA_N; pfam01330
585397005716	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
585397005717	hypothetical protein; Provisional; Region: PRK11470
585397005718	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
585397005719	active site
585397005720	putative DNA-binding cleft [nucleotide binding]; other site
585397005721	dimer interface [polypeptide binding]; other site
585397005722	hypothetical protein; Validated; Region: PRK00110
585397005723	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
585397005724	nudix motif; other site
585397005725	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
585397005726	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
585397005727	dimer interface [polypeptide binding]; other site
585397005728	anticodon binding site; other site
585397005729	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
585397005730	homodimer interface [polypeptide binding]; other site
585397005731	motif 1; other site
585397005732	active site
585397005733	motif 2; other site
585397005734	GAD domain; Region: GAD; pfam02938
585397005735	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
585397005736	motif 3; other site
585397005737	Isochorismatase family; Region: Isochorismatase; pfam00857
585397005738	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
585397005739	catalytic triad [active]
585397005740	conserved cis-peptide bond; other site
585397005741	DinI-like family; Region: DinI; pfam06183
585397005742	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
585397005743	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cl00185
585397005744	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
585397005745	Autotransporter beta-domain; Region: Autotransporter; pfam03797
585397005746	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
585397005747	trimer interface [polypeptide binding]; other site
585397005748	YadA-like C-terminal region; Region: YadA; pfam03895
585397005749	Domain of unknown function (DUF4376); Region: DUF4376; pfam14301
585397005750	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
585397005751	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
585397005752	Phage-related protein, tail component [Function unknown]; Region: COG4733
585397005753	Putative phage tail protein; Region: Phage-tail_3; pfam13550
585397005754	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
585397005755	Interdomain contacts; other site
585397005756	Cytokine receptor motif; other site
585397005757	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
585397005758	Fibronectin type III protein; Region: DUF3672; pfam12421
585397005759	Phage-related protein, tail component [Function unknown]; Region: COG4723
585397005760	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
585397005761	MPN+ (JAMM) motif; other site
585397005762	Zinc-binding site [ion binding]; other site
585397005763	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
585397005764	NlpC/P60 family; Region: NLPC_P60; cl17555
585397005765	Phage-related protein [Function unknown]; Region: gp18; COG4672
585397005766	Phage-related protein [Function unknown]; Region: COG4718
585397005767	Phage-related minor tail protein [Function unknown]; Region: COG5281
585397005768	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
585397005769	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
585397005770	Minor tail protein T; Region: Phage_tail_T; cl05636
585397005771	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; pfam06894
585397005772	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
585397005773	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
585397005774	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
585397005775	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
585397005776	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
585397005777	DNA packaging protein FI; Region: Packaging_FI; pfam14000
585397005778	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
585397005779	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
585397005780	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
585397005781	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
585397005782	tandem repeat interface [polypeptide binding]; other site
585397005783	oligomer interface [polypeptide binding]; other site
585397005784	active site residues [active]
585397005785	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
585397005786	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
585397005787	gpW; Region: gpW; pfam02831
585397005788	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
585397005789	Phage DNA packaging protein, Nu1 subunit of terminase [DNA replication, recombination, and repair]; Region: COG4220
585397005790	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
585397005791	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
585397005792	catalytic residues [active]
585397005793	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
585397005794	Lysis protein S; Region: Lysis_S; pfam04971
585397005795	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
585397005796	Protein of unknown function (DUF968); Region: DUF968; pfam06147
585397005797	KilA-N domain; Region: KilA-N; pfam04383
585397005798	Endodeoxyribonuclease RusA; Region: RusA; pfam05866
585397005799	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
585397005800	DNA N-6-adenine-methyltransferase (Dam); Region: Dam; pfam05869
585397005801	Ash protein family; Region: Phage_ASH; pfam10554
585397005802	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
585397005803	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397005804	non-specific DNA binding site [nucleotide binding]; other site
585397005805	salt bridge; other site
585397005806	sequence-specific DNA binding site [nucleotide binding]; other site
585397005807	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
585397005808	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397005809	non-specific DNA binding site [nucleotide binding]; other site
585397005810	salt bridge; other site
585397005811	sequence-specific DNA binding site [nucleotide binding]; other site
585397005812	Predicted transcriptional regulator [Transcription]; Region: COG2932
585397005813	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
585397005814	Catalytic site [active]
585397005815	Putative exonuclease, RdgC; Region: RdgC; cl01122
585397005816	Predicted hydrolases of HD superfamily [General function prediction only]; Region: COG1896
585397005817	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
585397005818	Protein of unknown function (DUF551); Region: DUF551; pfam04448
585397005819	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
585397005820	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
585397005821	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
585397005822	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
585397005823	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
585397005824	Int/Topo IB signature motif; other site
585397005825	hypothetical protein; Provisional; Region: PRK10302
585397005826	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
585397005827	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397005828	S-adenosylmethionine binding site [chemical binding]; other site
585397005829	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397005830	S-adenosylmethionine binding site [chemical binding]; other site
585397005831	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
585397005832	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
585397005833	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
585397005834	molybdopterin cofactor binding site [chemical binding]; other site
585397005835	substrate binding site [chemical binding]; other site
585397005836	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
585397005837	molybdopterin cofactor binding site; other site
585397005838	trimethylamine-N-oxide reductase c-type cytochrome TorC; Region: torC; TIGR02162
585397005839	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
585397005840	copper homeostasis protein CutC; Provisional; Region: PRK11572
585397005841	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
585397005842	putative metal binding site [ion binding]; other site
585397005843	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
585397005844	arginyl-tRNA synthetase; Region: argS; TIGR00456
585397005845	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
585397005846	active site
585397005847	HIGH motif; other site
585397005848	KMSK motif region; other site
585397005849	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
585397005850	tRNA binding surface [nucleotide binding]; other site
585397005851	anticodon binding site; other site
585397005852	Flagellar protein FlhE; Region: FlhE; pfam06366
585397005853	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
585397005854	FHIPEP family; Region: FHIPEP; pfam00771
585397005855	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
585397005856	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
585397005857	chemotaxis regulator CheZ; Provisional; Region: PRK11166
585397005858	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
585397005859	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397005860	active site
585397005861	phosphorylation site [posttranslational modification]
585397005862	intermolecular recognition site; other site
585397005863	dimerization interface [polypeptide binding]; other site
585397005864	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
585397005865	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397005866	active site
585397005867	phosphorylation site [posttranslational modification]
585397005868	intermolecular recognition site; other site
585397005869	dimerization interface [polypeptide binding]; other site
585397005870	CheB methylesterase; Region: CheB_methylest; pfam01339
585397005871	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
585397005872	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
585397005873	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397005874	S-adenosylmethionine binding site [chemical binding]; other site
585397005875	fragment of methyl-accepting protein IV (partial);Evidence 7 : Gene remnant; Product type r : regulator
585397005876	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
585397005877	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
585397005878	dimer interface [polypeptide binding]; other site
585397005879	ligand binding site [chemical binding]; other site
585397005880	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585397005881	dimerization interface [polypeptide binding]; other site
585397005882	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
585397005883	dimer interface [polypeptide binding]; other site
585397005884	putative CheW interface [polypeptide binding]; other site
585397005885	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
585397005886	putative CheA interaction surface; other site
585397005887	chemotaxis protein CheA; Provisional; Region: PRK10547
585397005888	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
585397005889	putative binding surface; other site
585397005890	active site
585397005891	CheY binding; Region: CheY-binding; pfam09078
585397005892	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
585397005893	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397005894	ATP binding site [chemical binding]; other site
585397005895	Mg2+ binding site [ion binding]; other site
585397005896	G-X-G motif; other site
585397005897	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
585397005898	flagellar motor protein MotB; Validated; Region: motB; PRK09041
585397005899	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
585397005900	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
585397005901	ligand binding site [chemical binding]; other site
585397005902	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
585397005903	flagellar motor protein MotA; Validated; Region: PRK09110
585397005904	transcriptional activator FlhC; Provisional; Region: PRK12722
585397005905	transcriptional activator FlhD; Provisional; Region: PRK02909
585397005906	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
585397005907	Ligand Binding Site [chemical binding]; other site
585397005908	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
585397005909	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
585397005910	active site
585397005911	homotetramer interface [polypeptide binding]; other site
585397005912	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
585397005913	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
585397005914	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585397005915	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585397005916	TM-ABC transporter signature motif; other site
585397005917	L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288
585397005918	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
585397005919	Walker A/P-loop; other site
585397005920	ATP binding site [chemical binding]; other site
585397005921	Q-loop/lid; other site
585397005922	ABC transporter signature motif; other site
585397005923	Walker B; other site
585397005924	D-loop; other site
585397005925	H-loop/switch region; other site
585397005926	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
585397005927	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
585397005928	Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540
585397005929	ligand binding site [chemical binding]; other site
585397005930	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397005931	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397005932	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397005933	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397005934	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
585397005935	Ferritin-like domain; Region: Ferritin; pfam00210
585397005936	ferroxidase diiron center [ion binding]; other site
585397005937	Protein of unknown function (DUF2766); Region: DUF2766; pfam10964
585397005938	YecR-like lipoprotein; Region: YecR; pfam13992
585397005939	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
585397005940	Ferritin-like domain; Region: Ferritin; pfam00210
585397005941	ferroxidase diiron center [ion binding]; other site
585397005942	probable metal-binding protein; Region: matur_matur; TIGR03853
585397005943	tyrosine transporter TyrP; Provisional; Region: PRK15132
585397005944	aromatic amino acid transport protein; Region: araaP; TIGR00837
585397005945	hypothetical protein; Provisional; Region: PRK10396
585397005946	yecA family protein; Region: ygfB_yecA; TIGR02292
585397005947	SEC-C motif; Region: SEC-C; pfam02810
585397005948	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
585397005949	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
585397005950	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
585397005951	GIY-YIG motif/motif A; other site
585397005952	active site
585397005953	catalytic site [active]
585397005954	putative DNA binding site [nucleotide binding]; other site
585397005955	metal binding site [ion binding]; metal-binding site
585397005956	UvrB/uvrC motif; Region: UVR; pfam02151
585397005957	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
585397005958	Helix-hairpin-helix motif; Region: HHH; pfam00633
585397005959	response regulator; Provisional; Region: PRK09483
585397005960	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397005961	active site
585397005962	phosphorylation site [posttranslational modification]
585397005963	intermolecular recognition site; other site
585397005964	dimerization interface [polypeptide binding]; other site
585397005965	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585397005966	DNA binding residues [nucleotide binding]
585397005967	dimerization interface [polypeptide binding]; other site
585397005968	hypothetical protein; Provisional; Region: PRK10613
585397005969	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
585397005970	Autoinducer binding domain; Region: Autoind_bind; pfam03472
585397005971	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585397005972	DNA binding residues [nucleotide binding]
585397005973	dimerization interface [polypeptide binding]; other site
585397005974	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
585397005975	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
585397005976	Walker A/P-loop; other site
585397005977	ATP binding site [chemical binding]; other site
585397005978	Q-loop/lid; other site
585397005979	ABC transporter signature motif; other site
585397005980	Walker B; other site
585397005981	D-loop; other site
585397005982	H-loop/switch region; other site
585397005983	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
585397005984	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397005985	dimer interface [polypeptide binding]; other site
585397005986	conserved gate region; other site
585397005987	putative PBP binding loops; other site
585397005988	ABC-ATPase subunit interface; other site
585397005989	D-cysteine desulfhydrase; Validated; Region: PRK03910
585397005990	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
585397005991	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397005992	catalytic residue [active]
585397005993	cystine transporter subunit; Provisional; Region: PRK11260
585397005994	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585397005995	substrate binding pocket [chemical binding]; other site
585397005996	membrane-bound complex binding site; other site
585397005997	hinge residues; other site
585397005998	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
585397005999	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
585397006000	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
585397006001	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
585397006002	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
585397006003	DNA binding residues [nucleotide binding]
585397006004	flagellin; Validated; Region: PRK08026
585397006005	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
585397006006	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
585397006007	flagellar capping protein; Reviewed; Region: fliD; PRK08032
585397006008	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
585397006009	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
585397006010	Flagellar protein FliS; Region: FliS; cl00654
585397006011	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
585397006012	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
585397006013	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
585397006014	active site
585397006015	Na/Ca binding site [ion binding]; other site
585397006016	catalytic site [active]
585397006017	lipoprotein; Provisional; Region: PRK10397
585397006018	putative inner membrane protein; Provisional; Region: PRK11099
585397006019	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
585397006020	CPxP  motif; other site
585397006021	hypothetical protein; Provisional; Region: PRK09951
585397006022	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
585397006023	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
585397006024	Probable transposase; Region: OrfB_IS605; pfam01385
585397006025	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
585397006026	Transposase IS200 like; Region: Y1_Tnp; pfam01797
585397006027	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
585397006028	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
585397006029	substrate binding site [chemical binding]; other site
585397006030	multidrug efflux protein; Reviewed; Region: emrE; PRK09541
585397006031	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
585397006032	flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); Region: fliF; TIGR00206
585397006033	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
585397006034	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
585397006035	flagellar motor switch protein FliG; Region: fliG; TIGR00207
585397006036	FliG C-terminal domain; Region: FliG_C; pfam01706
585397006037	flagellar assembly protein H; Validated; Region: fliH; PRK05687
585397006038	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
585397006039	Flagellar assembly protein FliH; Region: FliH; pfam02108
585397006040	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
585397006041	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
585397006042	Walker A motif/ATP binding site; other site
585397006043	Walker B motif; other site
585397006044	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
585397006045	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
585397006046	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
585397006047	flagellar hook-length control protein; Provisional; Region: PRK10118
585397006048	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
585397006049	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
585397006050	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
585397006051	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
585397006052	flagellar motor switch protein; Validated; Region: fliN; PRK05698
585397006053	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
585397006054	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
585397006055	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
585397006056	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
585397006057	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
585397006058	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585397006059	DNA binding residues [nucleotide binding]
585397006060	dimerization interface [polypeptide binding]; other site
585397006061	hypothetical protein; Provisional; Region: PRK10708
585397006062	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
585397006063	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
585397006064	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397006065	active site
585397006066	motif I; other site
585397006067	motif II; other site
585397006068	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
585397006069	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585397006070	metal binding site [ion binding]; metal-binding site
585397006071	active site
585397006072	I-site; other site
585397006073	Uncharacterized small protein [Function unknown]; Region: COG5475
585397006074	hypothetical protein; Provisional; Region: PRK10062
585397006075	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
585397006076	EamA-like transporter family; Region: EamA; pfam00892
585397006077	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
585397006078	additional DNA contacts [nucleotide binding]; other site
585397006079	mismatch recognition site; other site
585397006080	active site
585397006081	zinc binding site [ion binding]; other site
585397006082	DNA intercalation site [nucleotide binding]; other site
585397006083	DNA cytosine methylase; Provisional; Region: PRK10458
585397006084	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
585397006085	cofactor binding site; other site
585397006086	DNA binding site [nucleotide binding]
585397006087	substrate interaction site [chemical binding]; other site
585397006088	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
585397006089	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
585397006090	Zn2+ binding site [ion binding]; other site
585397006091	Mg2+ binding site [ion binding]; other site
585397006092	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
585397006093	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
585397006094	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
585397006095	eyelet of channel; other site
585397006096	trimer interface [polypeptide binding]; other site
585397006097	chaperone protein HchA; Provisional; Region: PRK04155
585397006098	Type 1 glutamine amidotransferase (GATase1)-like domain found in Escherichia coli Hsp31 protein (EcHsp31); Region: GATase1_EcHsp31_like; cd03148
585397006099	dimer interface [polypeptide binding]; other site
585397006100	metal binding site [ion binding]; metal-binding site
585397006101	potential oxyanion hole; other site
585397006102	potential catalytic triad [active]
585397006103	conserved cys residue [active]
585397006104	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
585397006105	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585397006106	dimer interface [polypeptide binding]; other site
585397006107	phosphorylation site [posttranslational modification]
585397006108	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397006109	ATP binding site [chemical binding]; other site
585397006110	Mg2+ binding site [ion binding]; other site
585397006111	G-X-G motif; other site
585397006112	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
585397006113	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397006114	active site
585397006115	phosphorylation site [posttranslational modification]
585397006116	intermolecular recognition site; other site
585397006117	dimerization interface [polypeptide binding]; other site
585397006118	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585397006119	DNA binding site [nucleotide binding]
585397006120	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
585397006121	active site
585397006122	homotetramer interface [polypeptide binding]; other site
585397006123	TMAO/DMSO reductase; Reviewed; Region: PRK05363
585397006124	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
585397006125	Moco binding site; other site
585397006126	metal coordination site [ion binding]; other site
585397006127	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
585397006128	zinc/cadmium-binding protein; Provisional; Region: PRK10306
585397006129	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
585397006130	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
585397006131	integrase; Provisional; Region: PRK09692
585397006132	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
585397006133	active site
585397006134	Int/Topo IB signature motif; other site
585397006135	salicylate synthase Irp9; Reviewed; Region: PRK06772
585397006136	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
585397006137	siderophore transporter, RhtX/FptX family; Region: sider_RhtX_FptX; TIGR02718
585397006138	muropeptide transporter; Validated; Region: ampG; cl17669
585397006139	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
585397006140	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397006141	Walker A/P-loop; other site
585397006142	ATP binding site [chemical binding]; other site
585397006143	Q-loop/lid; other site
585397006144	ABC transporter signature motif; other site
585397006145	Walker B; other site
585397006146	D-loop; other site
585397006147	H-loop/switch region; other site
585397006148	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
585397006149	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
585397006150	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397006151	Walker A/P-loop; other site
585397006152	ATP binding site [chemical binding]; other site
585397006153	Q-loop/lid; other site
585397006154	ABC transporter signature motif; other site
585397006155	Walker B; other site
585397006156	D-loop; other site
585397006157	H-loop/switch region; other site
585397006158	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
585397006159	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397006160	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
585397006161	Condensation domain; Region: Condensation; pfam00668
585397006162	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
585397006163	Nonribosomal peptide synthase; Region: NRPS; pfam08415
585397006164	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114
585397006165	acyl-activating enzyme (AAE) consensus motif; other site
585397006166	AMP binding site [chemical binding]; other site
585397006167	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397006168	S-adenosylmethionine binding site [chemical binding]; other site
585397006169	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
585397006170	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
585397006171	Condensation domain; Region: Condensation; pfam00668
585397006172	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
585397006173	Nonribosomal peptide synthase; Region: NRPS; pfam08415
585397006174	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
585397006175	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
585397006176	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
585397006177	active site
585397006178	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
585397006179	Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827
585397006180	Methyltransferase domain; Region: Methyltransf_12; pfam08242
585397006181	ketoreductase (KR) and fatty acid synthase (FAS), complex (x) SDRs; Region: KR_FAS_SDR_x; cd05274
585397006182	KR domain; Region: KR; pfam08659
585397006183	NADP binding site [chemical binding]; other site
585397006184	active site
585397006185	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
585397006186	Condensation domain; Region: Condensation; pfam00668
585397006187	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
585397006188	Nonribosomal peptide synthase; Region: NRPS; pfam08415
585397006189	Methyltransferase domain; Region: Methyltransf_12; pfam08242
585397006190	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
585397006191	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
585397006192	Oxidoreductase (NAD-binding), involved in siderophore biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PchG; COG4693
585397006193	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
585397006194	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
585397006195	Peptide arylation enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntE; COG1021
585397006196	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
585397006197	acyl-activating enzyme (AAE) consensus motif; other site
585397006198	active site
585397006199	AMP binding site [chemical binding]; other site
585397006200	substrate binding site [chemical binding]; other site
585397006201	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
585397006202	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585397006203	N-terminal plug; other site
585397006204	ligand-binding site [chemical binding]; other site
585397006205	Protein of unknown function (DUF2857); Region: DUF2857; pfam11198
585397006206	phage/conjugal plasmid C-4 type zinc finger protein, TraR family; Region: C4_traR_proteo; TIGR02419
585397006207	Haemolysin expression modulating protein; Region: HHA; cl11501
585397006208	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
585397006209	N-acetyl-D-glucosamine binding site [chemical binding]; other site
585397006210	catalytic residue [active]
585397006211	TrbC/VIRB2 family; Region: TrbC; cl01583
585397006212	Type IV secretory pathway, VirB3-like protein; Region: VirB3; cl01501
585397006213	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
585397006214	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
585397006215	P-type DNA transfer protein VirB5; Region: VirB5; TIGR02791
585397006216	Type IV secretion system proteins; Region: T4SS; pfam07996
585397006217	TrbL/VirB6 plasmid conjugal transfer protein; Region: TrbL; pfam04610
585397006218	VirB8 protein; Region: VirB8; pfam04335
585397006219	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cl11423
585397006220	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
585397006221	VirB7 interaction site; other site
585397006222	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
585397006223	P-type DNA transfer ATPase VirB11; Region: VirB11; TIGR02788
585397006224	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
585397006225	Walker A motif; other site
585397006226	hexamer interface [polypeptide binding]; other site
585397006227	ATP binding site [chemical binding]; other site
585397006228	Walker B motif; other site
585397006229	Cag pathogenicity island protein Cag12; Region: Cag12; pfam13117
585397006230	TrbM; Region: TrbM; pfam07424
585397006231	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
585397006232	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
585397006233	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
585397006234	Transposase; Region: HTH_Tnp_1; pfam01527
585397006235	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397006236	Walker A/P-loop; other site
585397006237	ATP binding site [chemical binding]; other site
585397006238	Q-loop/lid; other site
585397006239	ABC transporter signature motif; other site
585397006240	AAA domain; Region: AAA_21; pfam13304
585397006241	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
585397006242	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
585397006243	HsdM N-terminal domain; Region: HsdM_N; pfam12161
585397006244	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
585397006245	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397006246	S-adenosylmethionine binding site [chemical binding]; other site
585397006247	putative invasin; Provisional; Region: PRK10177
585397006248	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
585397006249	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
585397006250	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
585397006251	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
585397006252	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
585397006253	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
585397006254	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
585397006255	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
585397006256	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
585397006257	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
585397006258	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
585397006259	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
585397006260	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
585397006261	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
585397006262	fragment of conserved hypothetical protein (part 2);Evidence 7 : Gene remnant
585397006263	fragment of conserved hypothetical protein (part 1);Evidence 7 : Gene remnant
585397006264	shikimate transporter; Provisional; Region: PRK09952
585397006265	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397006266	putative substrate translocation pore; other site
585397006267	AMP nucleosidase; Provisional; Region: PRK08292
585397006268	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
585397006269	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
585397006270	hypothetical protein; Provisional; Region: PRK12378
585397006271	MATE family multidrug exporter; Provisional; Region: PRK10189
585397006272	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
585397006273	integrase; Provisional; Region: PRK09692
585397006274	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
585397006275	active site
585397006276	Int/Topo IB signature motif; other site
585397006277	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
585397006278	DNA methylase; Region: N6_N4_Mtase; pfam01555
585397006279	DNA methylase; Region: N6_N4_Mtase; cl17433
585397006280	Restriction endonuclease [Defense mechanisms]; Region: COG3587
585397006281	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585397006282	ATP binding site [chemical binding]; other site
585397006283	Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917
585397006284	Conjugal transfer protein TraD; Region: TraD; pfam06412
585397006285	Competence protein CoiA-like family; Region: CoiA; cl11541
585397006286	MobA/MobL family; Region: MobA_MobL; pfam03389
585397006287	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585397006288	putative heme d1 biosynthesis radical SAM protein NirJ2; Region: rSAM_NirJ2; TIGR04055
585397006289	FeS/SAM binding site; other site
585397006290	Domain of unknown function (DUF4008); Region: DUF4008; cl14869
585397006291	Predicted Fe-S oxidoreductases [General function prediction only]; Region: COG0535
585397006292	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585397006293	FeS/SAM binding site; other site
585397006294	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
585397006295	spermidine synthase; Provisional; Region: PRK03612
585397006296	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
585397006297	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397006298	non-specific DNA binding site [nucleotide binding]; other site
585397006299	salt bridge; other site
585397006300	sequence-specific DNA binding site [nucleotide binding]; other site
585397006301	Competence protein CoiA-like family; Region: CoiA; cl11541
585397006302	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
585397006303	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
585397006304	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
585397006305	transcriptional regulator Cbl; Reviewed; Region: cbl; PRK12679
585397006306	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397006307	The C-terminal substrate binding domain of LysR-type transcriptional regulator Cbl, which is required for expression of sulfate starvation-inducible (ssi) genes, contains the type 2 periplasmic binding fold; Region: PBP2_Cbl; cd08444
585397006308	putative substrate binding site [chemical binding]; other site
585397006309	dimerization interface [polypeptide binding]; other site
585397006310	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
585397006311	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397006312	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
585397006313	putative dimerization interface [polypeptide binding]; other site
585397006314	L,D-transpeptidase; Provisional; Region: PRK10190
585397006315	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
585397006316	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
585397006317	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
585397006318	putative dimer interface [polypeptide binding]; other site
585397006319	active site pocket [active]
585397006320	putative cataytic base [active]
585397006321	cobalamin 5'-phosphate synthase/cobalamin synthase; Region: cobS; TIGR00317
585397006322	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
585397006323	homotrimer interface [polypeptide binding]; other site
585397006324	Walker A motif; other site
585397006325	GTP binding site [chemical binding]; other site
585397006326	Walker B motif; other site
585397006327	fragment of conserved hypothetical protein, putative Cobalamin biosynthesis protein CbiG (partial);Evidence 7 : Gene remnant
585397006328	fragment of putative outer membrane receptor for iron compound or colicin (partial);Evidence 7 : Gene remnant; Product type pt : putative transporter
585397006329	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
585397006330	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
585397006331	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
585397006332	fragment of putative carbohydrate kinase (part 1);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397006333	fragment of putative carbohydrate kinase (part 2);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397006334	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
585397006335	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
585397006336	Protein of unknown function, DUF606; Region: DUF606; pfam04657
585397006337	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
585397006338	active site
585397006339	substrate binding pocket [chemical binding]; other site
585397006340	homodimer interaction site [polypeptide binding]; other site
585397006341	fragment of gamma-glutamyltranspeptidase (partial);Evidence 7 : Gene remnant; Product type e : enzyme
585397006342	remnant of Gamma-glutamyltranspeptidase precursor (ggt gene);Evidence 7 : Gene remnant; PubMedId : 2570061, 88106604, 96015152, 96362161, 1360205; Product type e : enzyme
585397006343	transposase, ISL3 family (part 2);Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
585397006344	transposase, ISL3 family (part 1);Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
585397006345	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
585397006346	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
585397006347	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
585397006348	Antirestriction protein; Region: Antirestrict; pfam03230
585397006349	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
585397006350	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
585397006351	MPN+ (JAMM) motif; other site
585397006352	Zinc-binding site [ion binding]; other site
585397006353	Protein of unknown function (DUF987); Region: DUF987; pfam06174
585397006354	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
585397006355	fragment of toxin of the YeeV-YeeU toxin-antitoxin system; CP4-44 prophage (partial);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585397006356	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
585397006357	Switch II region; other site
585397006358	G4 box; other site
585397006359	G5 box; other site
585397006360	hypothetical protein; Provisional; Region: PRK05423
585397006361	Predicted membrane protein [Function unknown]; Region: COG1289
585397006362	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
585397006363	DNA gyrase inhibitor; Provisional; Region: PRK10016
585397006364	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
585397006365	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
585397006366	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
585397006367	exonuclease I; Provisional; Region: sbcB; PRK11779
585397006368	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
585397006369	active site
585397006370	catalytic site [active]
585397006371	substrate binding site [chemical binding]; other site
585397006372	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
585397006373	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
585397006374	CPxP  motif; other site
585397006375	putative selenium metabolism protein, YedE family; Region: seleno_YedE; TIGR04112
585397006376	Sulphur transport; Region: Sulf_transp; pfam04143
585397006377	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
585397006378	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397006379	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
585397006380	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
585397006381	dimerization interface [polypeptide binding]; other site
585397006382	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
585397006383	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
585397006384	putative NAD(P) binding site [chemical binding]; other site
585397006385	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
585397006386	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
585397006387	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
585397006388	Histidinol dehydrogenase; Region: Histidinol_dh; pfam00815
585397006389	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
585397006390	NAD binding site [chemical binding]; other site
585397006391	dimerization interface [polypeptide binding]; other site
585397006392	product binding site; other site
585397006393	substrate binding site [chemical binding]; other site
585397006394	zinc binding site [ion binding]; other site
585397006395	catalytic residues [active]
585397006396	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
585397006397	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585397006398	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397006399	homodimer interface [polypeptide binding]; other site
585397006400	catalytic residue [active]
585397006401	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
585397006402	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397006403	active site
585397006404	motif I; other site
585397006405	motif II; other site
585397006406	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
585397006407	putative active site pocket [active]
585397006408	4-fold oligomerization interface [polypeptide binding]; other site
585397006409	metal binding residues [ion binding]; metal-binding site
585397006410	3-fold/trimer interface [polypeptide binding]; other site
585397006411	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
585397006412	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
585397006413	putative active site [active]
585397006414	oxyanion strand; other site
585397006415	catalytic triad [active]
585397006416	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
585397006417	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
585397006418	catalytic residues [active]
585397006419	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
585397006420	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
585397006421	substrate binding site [chemical binding]; other site
585397006422	glutamase interaction surface [polypeptide binding]; other site
585397006423	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
585397006424	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
585397006425	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
585397006426	metal binding site [ion binding]; metal-binding site
585397006427	chain length determinant protein WzzB; Provisional; Region: PRK15471
585397006428	Chain length determinant protein; Region: Wzz; pfam02706
585397006429	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
585397006430	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
585397006431	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
585397006432	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
585397006433	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
585397006434	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
585397006435	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
585397006436	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
585397006437	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
585397006438	active site
585397006439	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
585397006440	This family is most closely related to the GT1 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be...; Region: GT1_amsD_like; cd03820
585397006441	putative ADP-binding pocket [chemical binding]; other site
585397006442	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
585397006443	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
585397006444	active site
585397006445	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
585397006446	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
585397006447	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
585397006448	active site
585397006449	HIGH motif; other site
585397006450	nucleotide binding site [chemical binding]; other site
585397006451	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
585397006452	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
585397006453	NAD binding site [chemical binding]; other site
585397006454	homodimer interface [polypeptide binding]; other site
585397006455	active site
585397006456	substrate binding site [chemical binding]; other site
585397006457	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
585397006458	active site
585397006459	tetramer interface; other site
585397006460	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
585397006461	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
585397006462	putative NAD(P) binding site [chemical binding]; other site
585397006463	active site
585397006464	putative substrate binding site [chemical binding]; other site
585397006465	putative colanic acid biosynthesis protein; Provisional; Region: wcaM; PRK10123
585397006466	colanic acid biosynthesis glycosyltransferase WcaL; Region: wcaL; TIGR04005
585397006467	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
585397006468	putative ADP-binding pocket [chemical binding]; other site
585397006469	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
585397006470	colanic acid biosynthesis pyruvyl transferase WcaK; Region: wcaK; TIGR04006
585397006471	colanic acid exporter; Provisional; Region: PRK10459
585397006472	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
585397006473	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
585397006474	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
585397006475	phosphomannomutase CpsG; Provisional; Region: PRK15414
585397006476	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
585397006477	active site
585397006478	substrate binding site [chemical binding]; other site
585397006479	metal binding site [ion binding]; metal-binding site
585397006480	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
585397006481	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
585397006482	Substrate binding site; other site
585397006483	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
585397006484	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
585397006485	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
585397006486	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
585397006487	active site
585397006488	GDP-Mannose binding site [chemical binding]; other site
585397006489	dimer interface [polypeptide binding]; other site
585397006490	modified nudix motif
585397006491	metal binding site [ion binding]; metal-binding site
585397006492	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
585397006493	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
585397006494	NADP binding site [chemical binding]; other site
585397006495	active site
585397006496	putative substrate binding site [chemical binding]; other site
585397006497	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
585397006498	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
585397006499	NADP-binding site; other site
585397006500	homotetramer interface [polypeptide binding]; other site
585397006501	substrate binding site [chemical binding]; other site
585397006502	homodimer interface [polypeptide binding]; other site
585397006503	active site
585397006504	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
585397006505	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
585397006506	putative trimer interface [polypeptide binding]; other site
585397006507	putative active site [active]
585397006508	putative substrate binding site [chemical binding]; other site
585397006509	putative CoA binding site [chemical binding]; other site
585397006510	putative glycosyl transferase; Provisional; Region: PRK10063
585397006511	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
585397006512	metal-binding site
585397006513	putative colanic acid polymerase WcaD; Region: WcaD; TIGR04010
585397006514	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
585397006515	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
585397006516	putative acyl transferase; Provisional; Region: PRK10191
585397006517	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
585397006518	trimer interface [polypeptide binding]; other site
585397006519	active site
585397006520	substrate binding site [chemical binding]; other site
585397006521	CoA binding site [chemical binding]; other site
585397006522	putative glycosyl transferase; Provisional; Region: PRK10018
585397006523	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
585397006524	active site
585397006525	tyrosine kinase; Provisional; Region: PRK11519
585397006526	Chain length determinant protein; Region: Wzz; pfam02706
585397006527	Chain length determinant protein; Region: Wzz; cl15801
585397006528	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
585397006529	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
585397006530	Low molecular weight phosphatase family; Region: LMWPc; cd00115
585397006531	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
585397006532	active site
585397006533	polysaccharide export protein Wza; Provisional; Region: PRK15078
585397006534	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
585397006535	SLBB domain; Region: SLBB; pfam10531
585397006536	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
585397006537	FOG: CBS domain [General function prediction only]; Region: COG0517
585397006538	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
585397006539	Transporter associated domain; Region: CorC_HlyC; smart01091
585397006540	putative assembly protein; Provisional; Region: PRK10833
585397006541	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
585397006542	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
585397006543	trimer interface [polypeptide binding]; other site
585397006544	active site
585397006545	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
585397006546	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
585397006547	ATP-binding site [chemical binding]; other site
585397006548	Sugar specificity; other site
585397006549	Pyrimidine base specificity; other site
585397006550	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
585397006551	putative diguanylate cyclase; Provisional; Region: PRK09776
585397006552	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585397006553	putative active site [active]
585397006554	heme pocket [chemical binding]; other site
585397006555	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585397006556	putative active site [active]
585397006557	heme pocket [chemical binding]; other site
585397006558	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585397006559	putative active site [active]
585397006560	heme pocket [chemical binding]; other site
585397006561	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585397006562	metal binding site [ion binding]; metal-binding site
585397006563	active site
585397006564	I-site; other site
585397006565	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585397006566	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
585397006567	AlkA N-terminal domain; Region: AlkA_N; smart01009
585397006568	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
585397006569	minor groove reading motif; other site
585397006570	helix-hairpin-helix signature motif; other site
585397006571	substrate binding pocket [chemical binding]; other site
585397006572	active site
585397006573	putative chaperone; Provisional; Region: PRK11678
585397006574	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
585397006575	nucleotide binding site [chemical binding]; other site
585397006576	putative NEF/HSP70 interaction site [polypeptide binding]; other site
585397006577	SBD interface [polypeptide binding]; other site
585397006578	Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only]; Region: COG4248
585397006579	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
585397006580	substrate binding site [chemical binding]; other site
585397006581	activation loop (A-loop); other site
585397006582	Y-family of DNA polymerases; Region: PolY; cl12025
585397006583	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3779
585397006584	Uncharacterized protein conserved in bacteria (DUF2314); Region: DUF2314; pfam10077
585397006585	Protein phosphatase 2C; Region: PP2C_2; pfam13672
585397006586	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
585397006587	metal ion-dependent adhesion site (MIDAS); other site
585397006588	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
585397006589	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585397006590	HlyD family secretion protein; Region: HlyD_3; pfam13437
585397006591	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
585397006592	Protein export membrane protein; Region: SecD_SecF; cl14618
585397006593	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
585397006594	putative transporter; Provisional; Region: PRK10504
585397006595	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397006596	putative substrate translocation pore; other site
585397006597	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
585397006598	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585397006599	dimerization interface [polypeptide binding]; other site
585397006600	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585397006601	dimer interface [polypeptide binding]; other site
585397006602	phosphorylation site [posttranslational modification]
585397006603	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397006604	ATP binding site [chemical binding]; other site
585397006605	Mg2+ binding site [ion binding]; other site
585397006606	G-X-G motif; other site
585397006607	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
585397006608	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397006609	active site
585397006610	phosphorylation site [posttranslational modification]
585397006611	intermolecular recognition site; other site
585397006612	dimerization interface [polypeptide binding]; other site
585397006613	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585397006614	DNA binding site [nucleotide binding]
585397006615	Uncharacterized conserved protein [Function unknown]; Region: COG3422
585397006616	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
585397006617	Domain of unknown function (DUF4034); Region: DUF4034; pfam13226
585397006618	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
585397006619	PcfJ-like protein; Region: PcfJ; pfam14284
585397006620	putative protease; Provisional; Region: PRK15452
585397006621	Peptidase family U32; Region: Peptidase_U32; pfam01136
585397006622	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
585397006623	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
585397006624	tail protein; Provisional; Region: D; PHA02561
585397006625	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
585397006626	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
585397006627	GpE+E' phage tail protein (fragment);Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin
585397006628	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
585397006629	major tail tube protein; Provisional; Region: FII; PHA02600
585397006630	major tail sheath protein; Provisional; Region: FI; PHA02560
585397006631	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
585397006632	active site
585397006633	DNA binding site [nucleotide binding]
585397006634	Int/Topo IB signature motif; other site
585397006635	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
585397006636	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
585397006637	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
585397006638	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
585397006639	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
585397006640	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
585397006641	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
585397006642	phage tail protein, P2 protein I family; Region: tail_P2_I; TIGR01634
585397006643	baseplate assembly protein; Provisional; Region: J; PHA02568
585397006644	baseplate wedge subunit; Provisional; Region: W; PHA02516
585397006645	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
585397006646	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
585397006647	fragment of conserved hypothetical protein (partial);Evidence 7 : Gene remnant
585397006648	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
585397006649	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397006650	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397006651	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397006652	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
585397006653	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
585397006654	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
585397006655	substrate binding site [chemical binding]; other site
585397006656	ATP binding site [chemical binding]; other site
585397006657	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
585397006658	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585397006659	DNA-binding site [nucleotide binding]; DNA binding site
585397006660	UTRA domain; Region: UTRA; pfam07702
585397006661	Lyzozyme M1 (1,4-beta-N-acetylmuramidase) [Cell envelope biogenesis, outer membrane]; Region: Acm; COG3757
585397006662	YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins; Region: GH25_YegX-like; cd06524
585397006663	active site
585397006664	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
585397006665	dimer interface [polypeptide binding]; other site
585397006666	substrate binding site [chemical binding]; other site
585397006667	ATP binding site [chemical binding]; other site
585397006668	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
585397006669	substrate binding site [chemical binding]; other site
585397006670	multimerization interface [polypeptide binding]; other site
585397006671	ATP binding site [chemical binding]; other site
585397006672	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
585397006673	putative metal binding site [ion binding]; other site
585397006674	putative homodimer interface [polypeptide binding]; other site
585397006675	putative homotetramer interface [polypeptide binding]; other site
585397006676	putative homodimer-homodimer interface [polypeptide binding]; other site
585397006677	putative allosteric switch controlling residues; other site
585397006678	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
585397006679	Predicted integral membrane protein [Function unknown]; Region: COG5455
585397006680	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
585397006681	putative fimbrial biosynthesis regulatory protein; Provisional; Region: PRK15216
585397006682	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
585397006683	PapC N-terminal domain; Region: PapC_N; pfam13954
585397006684	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585397006685	PapC C-terminal domain; Region: PapC_C; pfam13953
585397006686	putative fimbrial assembly chaperone protein StcB; Provisional; Region: PRK15253
585397006687	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585397006688	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
585397006689	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
585397006690	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
585397006691	antiporter inner membrane protein; Provisional; Region: PRK11670
585397006692	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
585397006693	Walker A motif; other site
585397006694	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
585397006695	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
585397006696	active site
585397006697	HIGH motif; other site
585397006698	KMSKS motif; other site
585397006699	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
585397006700	tRNA binding surface [nucleotide binding]; other site
585397006701	anticodon binding site; other site
585397006702	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
585397006703	dimer interface [polypeptide binding]; other site
585397006704	putative tRNA-binding site [nucleotide binding]; other site
585397006705	WGR domain of molybdate metabolism regulator and related proteins; Region: WGR_MMR_like; cd07996
585397006706	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
585397006707	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
585397006708	MoxR-like ATPases [General function prediction only]; Region: COG0714
585397006709	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397006710	Walker A motif; other site
585397006711	ATP binding site [chemical binding]; other site
585397006712	Walker B motif; other site
585397006713	arginine finger; other site
585397006714	VWA domain containing CoxE-like protein; Region: VWA_CoxE; pfam05762
585397006715	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
585397006716	metal ion-dependent adhesion site (MIDAS); other site
585397006717	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
585397006718	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
585397006719	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
585397006720	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
585397006721	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
585397006722	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397006723	active site
585397006724	phosphorylation site [posttranslational modification]
585397006725	intermolecular recognition site; other site
585397006726	dimerization interface [polypeptide binding]; other site
585397006727	LytTr DNA-binding domain; Region: LytTR; pfam04397
585397006728	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
585397006729	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
585397006730	GAF domain; Region: GAF; pfam01590
585397006731	Histidine kinase; Region: His_kinase; pfam06580
585397006732	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397006733	ATP binding site [chemical binding]; other site
585397006734	Mg2+ binding site [ion binding]; other site
585397006735	G-X-G motif; other site
585397006736	DinI-like family; Region: DinI; pfam06183
585397006737	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
585397006738	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cl00185
585397006739	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
585397006740	Autotransporter beta-domain; Region: Autotransporter; pfam03797
585397006741	YadA-like C-terminal region; Region: YadA; pfam03895
585397006742	Domain of unknown function (DUF4376); Region: DUF4376; pfam14301
585397006743	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
585397006744	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
585397006745	Phage-related protein, tail component [Function unknown]; Region: COG4733
585397006746	Putative phage tail protein; Region: Phage-tail_3; pfam13550
585397006747	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
585397006748	Interdomain contacts; other site
585397006749	Cytokine receptor motif; other site
585397006750	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
585397006751	Fibronectin type III protein; Region: DUF3672; pfam12421
585397006752	Phage-related protein, tail component [Function unknown]; Region: COG4723
585397006753	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
585397006754	MPN+ (JAMM) motif; other site
585397006755	Zinc-binding site [ion binding]; other site
585397006756	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
585397006757	NlpC/P60 family; Region: NLPC_P60; cl17555
585397006758	Prophage antirepressor [Transcription]; Region: COG3617
585397006759	BRO family, N-terminal domain; Region: Bro-N; smart01040
585397006760	Phage anti-repressor protein [Transcription]; Region: COG3561
585397006761	putative regulatory protein from phage origin (partial match);Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7999761, 10426954; Product type pr : putative regulator
585397006762	Mnt; Region: mnt; PHA01513
585397006763	Arc-like DNA binding domain; Region: Arc; pfam03869
585397006764	Caseinolytic protease (ClpP) is an ATP-dependent protease; Region: Clp_protease_like; cl15763
585397006765	active site
585397006766	Phage-related protein [Function unknown]; Region: gp18; COG4672
585397006767	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
585397006768	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
585397006769	trimer interface [polypeptide binding]; other site
585397006770	eyelet of channel; other site
585397006771	Phage-related protein [Function unknown]; Region: COG4718
585397006772	Phage-related minor tail protein [Function unknown]; Region: COG5281
585397006773	tape measure domain; Region: tape_meas_nterm; TIGR02675
585397006774	Tail length tape measure protein; Region: Phage_HK97_TLTM; pfam06120
585397006775	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
585397006776	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
585397006777	Protein of unknown function (DUF4035); Region: DUF4035; pfam13227
585397006778	Phage tail assembly chaperone; Region: Phage_TAC; pfam06222
585397006779	Immunoglobulin domain; Region: Ig; cd00096
585397006780	Protein of unknown function (DUF3168); Region: DUF3168; pfam11367
585397006781	phage protein, HK97 gp10 family; Region: phge_HK97_gp10; TIGR01725
585397006782	Bacteriophage head-tail adaptor [General function prediction only]; Region: COG5614
585397006783	Carbohydrate binding domain; Region: CBM_5_12; pfam02839
585397006784	Phage-related protein [Function unknown]; Region: COG4695
585397006785	phage portal protein, HK97 family; Region: portal_HK97; TIGR01537
585397006786	Caudovirus prohead protease; Region: Peptidase_U35; pfam04586
585397006787	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
585397006788	Phage capsid family; Region: Phage_capsid; pfam05065
585397006789	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
585397006790	Phage terminase, small subunit [DNA replication, recombination, and repair]; Region: XtmA; COG3728
585397006791	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
585397006792	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
585397006793	active site
585397006794	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
585397006795	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
585397006796	KilA-N domain; Region: KilA-N; pfam04383
585397006797	ORF11CD3 domain; Region: ORF11CD3; pfam10549
585397006798	Protein of unknown function (DUF3423); Region: DUF3423; pfam11903
585397006799	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
585397006800	Uncharacterized phage-encoded protein [Function unknown]; Region: COG3645
585397006801	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
585397006802	catalytic residues [active]
585397006803	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
585397006804	Lysis protein S; Region: Lysis_S; pfam04971
585397006805	Protein of unknown function (DUF826); Region: DUF826; pfam05696
585397006806	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
585397006807	Domain of unknown function (DUF303); Region: DUF303; pfam03629
585397006808	tellurium resistance terB-like protein; Region: terB_like; cl11965
585397006809	tellurite resistance protein terB; Region: terB; cd07176
585397006810	putative metal binding site [ion binding]; other site
585397006811	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
585397006812	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
585397006813	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
585397006814	Uncharacterized phage-encoded protein [Function unknown]; Region: COG3645
585397006815	ORF6N domain; Region: ORF6N; pfam10543
585397006816	Phage anti-repressor protein [Transcription]; Region: COG3561
585397006817	phage N-6-adenine-methyltransferase; Region: phage_N6A_met; TIGR01712
585397006818	NinB protein; Region: NinB; pfam05772
585397006819	restriction alleviation protein, Lar family; Region: anti_R_Lar; TIGR03655
585397006820	Replication protein P; Region: Phage_lambda_P; pfam06992
585397006821	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
585397006822	Bacteriophage CII protein; Region: Phage_CII; pfam05269
585397006823	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397006824	non-specific DNA binding site [nucleotide binding]; other site
585397006825	salt bridge; other site
585397006826	sequence-specific DNA binding site [nucleotide binding]; other site
585397006827	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397006828	non-specific DNA binding site [nucleotide binding]; other site
585397006829	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
585397006830	salt bridge; other site
585397006831	sequence-specific DNA binding site [nucleotide binding]; other site
585397006832	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
585397006833	Catalytic site [active]
585397006834	Bacteriophage lambda Kil protein; Region: Lambda_Kil; pfam06301
585397006835	Host-nuclease inhibitor protein Gam; Region: Gam; pfam06064
585397006836	phage recombination protein Bet; Region: bet_lambda; TIGR01913
585397006837	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
585397006838	DksA-like zinc finger domain containing protein; Region: PHA00080
585397006839	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
585397006840	Protein of unknown function (DUF550); Region: DUF550; pfam04447
585397006841	Protein of unknown function (DUF550); Region: DUF550; pfam04447
585397006842	Protein of unknown function (DUF551); Region: DUF551; pfam04448
585397006843	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
585397006844	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
585397006845	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
585397006846	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
585397006847	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
585397006848	Int/Topo IB signature motif; other site
585397006849	transcriptional regulator MirA; Provisional; Region: PRK15043
585397006850	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
585397006851	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
585397006852	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397006853	dimer interface [polypeptide binding]; other site
585397006854	conserved gate region; other site
585397006855	putative PBP binding loops; other site
585397006856	ABC-ATPase subunit interface; other site
585397006857	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
585397006858	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
585397006859	Walker A/P-loop; other site
585397006860	ATP binding site [chemical binding]; other site
585397006861	Q-loop/lid; other site
585397006862	ABC transporter signature motif; other site
585397006863	Walker B; other site
585397006864	D-loop; other site
585397006865	H-loop/switch region; other site
585397006866	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
585397006867	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397006868	dimer interface [polypeptide binding]; other site
585397006869	conserved gate region; other site
585397006870	ABC-ATPase subunit interface; other site
585397006871	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
585397006872	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
585397006873	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
585397006874	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
585397006875	D-lactate dehydrogenase; Provisional; Region: PRK11183
585397006876	FAD binding domain; Region: FAD_binding_4; pfam01565
585397006877	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
585397006878	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
585397006879	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
585397006880	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
585397006881	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
585397006882	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
585397006883	oxidoreductase; Provisional; Region: PRK12743
585397006884	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
585397006885	NAD(P) binding site [chemical binding]; other site
585397006886	active site
585397006887	Outer membrane efflux protein; Region: OEP; pfam02321
585397006888	Outer membrane efflux protein; Region: OEP; pfam02321
585397006889	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
585397006890	Transposase; Region: DEDD_Tnp_IS110; pfam01548
585397006891	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
585397006892	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
585397006893	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
585397006894	FMN binding site [chemical binding]; other site
585397006895	active site
585397006896	catalytic residues [active]
585397006897	substrate binding site [chemical binding]; other site
585397006898	hypothetical protein; Provisional; Region: PRK01821
585397006899	hypothetical protein; Provisional; Region: PRK10711
585397006900	cytidine deaminase; Provisional; Region: PRK09027
585397006901	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
585397006902	active site
585397006903	catalytic motif [active]
585397006904	Zn binding site [ion binding]; other site
585397006905	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
585397006906	active site
585397006907	catalytic motif [active]
585397006908	Zn binding site [ion binding]; other site
585397006909	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
585397006910	putative active site [active]
585397006911	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
585397006912	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
585397006913	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
585397006914	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585397006915	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
585397006916	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
585397006917	homodimer interface [polypeptide binding]; other site
585397006918	active site
585397006919	FMN binding site [chemical binding]; other site
585397006920	substrate binding site [chemical binding]; other site
585397006921	4Fe-4S binding domain; Region: Fer4; pfam00037
585397006922	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585397006923	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585397006924	TM-ABC transporter signature motif; other site
585397006925	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
585397006926	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
585397006927	Walker A/P-loop; other site
585397006928	ATP binding site [chemical binding]; other site
585397006929	Q-loop/lid; other site
585397006930	ABC transporter signature motif; other site
585397006931	Walker B; other site
585397006932	D-loop; other site
585397006933	H-loop/switch region; other site
585397006934	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
585397006935	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
585397006936	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
585397006937	ligand binding site [chemical binding]; other site
585397006938	calcium binding site [ion binding]; other site
585397006939	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
585397006940	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585397006941	DNA binding site [nucleotide binding]
585397006942	domain linker motif; other site
585397006943	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
585397006944	dimerization interface (closed form) [polypeptide binding]; other site
585397006945	ligand binding site [chemical binding]; other site
585397006946	Predicted membrane protein [Function unknown]; Region: COG2311
585397006947	hypothetical protein; Provisional; Region: PRK10835
585397006948	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
585397006949	homodecamer interface [polypeptide binding]; other site
585397006950	GTP cyclohydrolase I; Provisional; Region: PLN03044
585397006951	active site
585397006952	putative catalytic site residues [active]
585397006953	zinc binding site [ion binding]; other site
585397006954	GTP-CH-I/GFRP interaction surface; other site
585397006955	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
585397006956	S-formylglutathione hydrolase; Region: PLN02442
585397006957	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
585397006958	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585397006959	N-terminal plug; other site
585397006960	ligand-binding site [chemical binding]; other site
585397006961	lysine transporter; Provisional; Region: PRK10836
585397006962	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
585397006963	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397006964	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
585397006965	putative dimerization interface [polypeptide binding]; other site
585397006966	conserved hypothetical integral membrane protein; Region: TIGR00698
585397006967	endonuclease IV; Provisional; Region: PRK01060
585397006968	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
585397006969	AP (apurinic/apyrimidinic) site pocket; other site
585397006970	DNA interaction; other site
585397006971	Metal-binding active site; metal-binding site
585397006972	putative kinase; Provisional; Region: PRK09954
585397006973	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
585397006974	putative DNA binding site [nucleotide binding]; other site
585397006975	putative Zn2+ binding site [ion binding]; other site
585397006976	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
585397006977	substrate binding site [chemical binding]; other site
585397006978	ATP binding site [chemical binding]; other site
585397006979	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
585397006980	active site
585397006981	tetramer interface [polypeptide binding]; other site
585397006982	DNA-binding transcriptional activator YeiL; Provisional; Region: PRK10402
585397006983	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
585397006984	ligand binding site [chemical binding]; other site
585397006985	flexible hinge region; other site
585397006986	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
585397006987	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
585397006988	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
585397006989	Nucleoside recognition; Region: Gate; pfam07670
585397006990	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
585397006991	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
585397006992	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
585397006993	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
585397006994	substrate binding site [chemical binding]; other site
585397006995	ATP binding site [chemical binding]; other site
585397006996	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
585397006997	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
585397006998	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
585397006999	active site
585397007000	P-loop; other site
585397007001	phosphorylation site [posttranslational modification]
585397007002	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
585397007003	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
585397007004	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
585397007005	putative substrate binding site [chemical binding]; other site
585397007006	putative ATP binding site [chemical binding]; other site
585397007007	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
585397007008	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
585397007009	active site
585397007010	phosphorylation site [posttranslational modification]
585397007011	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
585397007012	dimerization domain swap beta strand [polypeptide binding]; other site
585397007013	regulatory protein interface [polypeptide binding]; other site
585397007014	active site
585397007015	regulatory phosphorylation site [posttranslational modification]; other site
585397007016	fragment of lactose/glucose efflux system (part 1);Evidence 7 : Gene remnant; Product type t : transporter
585397007017	fragment of lactose/glucose efflux system (part 2);Evidence 7 : Gene remnant; Product type t : transporter
585397007018	Flagellin N-methylase; Region: FliB; pfam03692
585397007019	elongation factor P; Provisional; Region: PRK04542
585397007020	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
585397007021	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
585397007022	RNA binding site [nucleotide binding]; other site
585397007023	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
585397007024	RNA binding site [nucleotide binding]; other site
585397007025	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
585397007026	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
585397007027	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
585397007028	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
585397007029	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
585397007030	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
585397007031	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
585397007032	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
585397007033	active site
585397007034	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
585397007035	NlpC/P60 family; Region: NLPC_P60; pfam00877
585397007036	phage resistance protein; Provisional; Region: PRK10551
585397007037	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
585397007038	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585397007039	fragment of putative oligopeptide transporter subunit ; periplasmic-binding component of ABC superfamily transporter (part 1);Evidence 7 : Gene remnant; Product type pt : putative transporter
585397007040	fragment of putative oligopeptide transporter subunit ; periplasmic-binding component of ABC superfamily transporter (part 2);Evidence 7 : Gene remnant; Product type pt : putative transporter
585397007041	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
585397007042	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397007043	dimer interface [polypeptide binding]; other site
585397007044	conserved gate region; other site
585397007045	putative PBP binding loops; other site
585397007046	ABC-ATPase subunit interface; other site
585397007047	microcin C ABC transporter permease; Provisional; Region: PRK15021
585397007048	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397007049	dimer interface [polypeptide binding]; other site
585397007050	conserved gate region; other site
585397007051	ABC-ATPase subunit interface; other site
585397007052	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
585397007053	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585397007054	Walker A/P-loop; other site
585397007055	ATP binding site [chemical binding]; other site
585397007056	Q-loop/lid; other site
585397007057	ABC transporter signature motif; other site
585397007058	Walker B; other site
585397007059	D-loop; other site
585397007060	H-loop/switch region; other site
585397007061	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
585397007062	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585397007063	Walker A/P-loop; other site
585397007064	ATP binding site [chemical binding]; other site
585397007065	Q-loop/lid; other site
585397007066	ABC transporter signature motif; other site
585397007067	Walker B; other site
585397007068	D-loop; other site
585397007069	H-loop/switch region; other site
585397007070	hypothetical protein; Provisional; Region: PRK11835
585397007071	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397007072	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
585397007073	putative substrate translocation pore; other site
585397007074	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
585397007075	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
585397007076	RNA binding surface [nucleotide binding]; other site
585397007077	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
585397007078	active site
585397007079	uracil binding [chemical binding]; other site
585397007080	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
585397007081	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585397007082	ATP binding site [chemical binding]; other site
585397007083	putative Mg++ binding site [ion binding]; other site
585397007084	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585397007085	nucleotide binding region [chemical binding]; other site
585397007086	ATP-binding site [chemical binding]; other site
585397007087	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
585397007088	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
585397007089	5S rRNA interface [nucleotide binding]; other site
585397007090	CTC domain interface [polypeptide binding]; other site
585397007091	L16 interface [polypeptide binding]; other site
585397007092	Nucleoid-associated protein [General function prediction only]; Region: COG3081
585397007093	nucleoid-associated protein NdpA; Validated; Region: PRK00378
585397007094	hypothetical protein; Provisional; Region: PRK13689
585397007095	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
585397007096	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
585397007097	Sulfatase; Region: Sulfatase; pfam00884
585397007098	integrase; Provisional; Region: PRK09692
585397007099	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
585397007100	active site
585397007101	Int/Topo IB signature motif; other site
585397007102	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
585397007103	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
585397007104	Ash protein family; Region: Phage_ASH; pfam10554
585397007105	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
585397007106	Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG5519
585397007107	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
585397007108	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
585397007109	ssDNA binding site [nucleotide binding]; other site
585397007110	dimer interface [polypeptide binding]; other site
585397007111	tetramer (dimer of dimers) interface [polypeptide binding]; other site
585397007112	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
585397007113	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
585397007114	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cl00185
585397007115	transcriptional regulator NarP; Provisional; Region: PRK10403
585397007116	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397007117	active site
585397007118	phosphorylation site [posttranslational modification]
585397007119	intermolecular recognition site; other site
585397007120	dimerization interface [polypeptide binding]; other site
585397007121	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585397007122	DNA binding residues [nucleotide binding]
585397007123	dimerization interface [polypeptide binding]; other site
585397007124	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
585397007125	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
585397007126	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585397007127	binding surface
585397007128	TPR motif; other site
585397007129	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
585397007130	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
585397007131	catalytic residues [active]
585397007132	central insert; other site
585397007133	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
585397007134	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13165
585397007135	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
585397007136	heme exporter protein CcmC; Region: ccmC; TIGR01191
585397007137	heme exporter protein CcmB; Region: ccmB; TIGR01190
585397007138	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
585397007139	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
585397007140	Walker A/P-loop; other site
585397007141	ATP binding site [chemical binding]; other site
585397007142	Q-loop/lid; other site
585397007143	ABC transporter signature motif; other site
585397007144	Walker B; other site
585397007145	D-loop; other site
585397007146	H-loop/switch region; other site
585397007147	cytochrome c-type protein NapC; Provisional; Region: PRK10617
585397007148	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
585397007149	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
585397007150	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
585397007151	4Fe-4S binding domain; Region: Fer4_5; pfam12801
585397007152	4Fe-4S binding domain; Region: Fer4_6; pfam12837
585397007153	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
585397007154	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
585397007155	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
585397007156	[4Fe-4S] binding site [ion binding]; other site
585397007157	molybdopterin cofactor binding site; other site
585397007158	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
585397007159	molybdopterin cofactor binding site; other site
585397007160	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
585397007161	ferredoxin-type protein; Provisional; Region: PRK10194
585397007162	tRNA synthetases class I (R); Region: tRNA-synt_1d; pfam00750
585397007163	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
585397007164	secondary substrate binding site; other site
585397007165	primary substrate binding site; other site
585397007166	inhibition loop; other site
585397007167	dimerization interface [polypeptide binding]; other site
585397007168	malate:quinone oxidoreductase; Validated; Region: PRK05257
585397007169	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
585397007170	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
585397007171	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
585397007172	Walker A/P-loop; other site
585397007173	ATP binding site [chemical binding]; other site
585397007174	Q-loop/lid; other site
585397007175	ABC transporter signature motif; other site
585397007176	Walker B; other site
585397007177	D-loop; other site
585397007178	H-loop/switch region; other site
585397007179	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
585397007180	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
585397007181	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
585397007182	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397007183	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397007184	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
585397007185	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
585397007186	DNA binding site [nucleotide binding]
585397007187	active site
585397007188	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
585397007189	ApbE family; Region: ApbE; pfam02424
585397007190	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
585397007191	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
585397007192	trimer interface [polypeptide binding]; other site
585397007193	eyelet of channel; other site
585397007194	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
585397007195	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397007196	ATP binding site [chemical binding]; other site
585397007197	G-X-G motif; other site
585397007198	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
585397007199	putative binding surface; other site
585397007200	active site
585397007201	transcriptional regulator RcsB; Provisional; Region: PRK10840
585397007202	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397007203	active site
585397007204	phosphorylation site [posttranslational modification]
585397007205	intermolecular recognition site; other site
585397007206	dimerization interface [polypeptide binding]; other site
585397007207	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585397007208	DNA binding residues [nucleotide binding]
585397007209	dimerization interface [polypeptide binding]; other site
585397007210	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
585397007211	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585397007212	dimer interface [polypeptide binding]; other site
585397007213	phosphorylation site [posttranslational modification]
585397007214	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397007215	ATP binding site [chemical binding]; other site
585397007216	Mg2+ binding site [ion binding]; other site
585397007217	G-X-G motif; other site
585397007218	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
585397007219	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397007220	active site
585397007221	phosphorylation site [posttranslational modification]
585397007222	intermolecular recognition site; other site
585397007223	dimerization interface [polypeptide binding]; other site
585397007224	sensory histidine kinase AtoS; Provisional; Region: PRK11360
585397007225	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585397007226	putative active site [active]
585397007227	heme pocket [chemical binding]; other site
585397007228	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585397007229	dimer interface [polypeptide binding]; other site
585397007230	phosphorylation site [posttranslational modification]
585397007231	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397007232	ATP binding site [chemical binding]; other site
585397007233	Mg2+ binding site [ion binding]; other site
585397007234	G-X-G motif; other site
585397007235	acetoacetate metabolism regulatory protein AtoC; Provisional; Region: PRK11361
585397007236	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397007237	active site
585397007238	phosphorylation site [posttranslational modification]
585397007239	intermolecular recognition site; other site
585397007240	dimerization interface [polypeptide binding]; other site
585397007241	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397007242	Walker A motif; other site
585397007243	ATP binding site [chemical binding]; other site
585397007244	Walker B motif; other site
585397007245	arginine finger; other site
585397007246	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
585397007247	acetyl-CoA:acetoacetyl-CoA transferase subunit alpha; Provisional; Region: PRK09920
585397007248	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
585397007249	Short chain fatty acid transporter; Region: SCFA_trans; pfam02667
585397007250	putative acyltransferase; Provisional; Region: PRK05790
585397007251	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
585397007252	dimer interface [polypeptide binding]; other site
585397007253	active site
585397007254	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4676
585397007255	Uncharacterized protein conserved in bacteria (DUF2135); Region: DUF2135; pfam09906
585397007256	Predicted secreted protein [Function unknown]; Region: COG5445
585397007257	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
585397007258	Predicted secreted protein [Function unknown]; Region: COG5445
585397007259	Stage II sporulation protein; Region: SpoIID; pfam08486
585397007260	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
585397007261	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
585397007262	MG2 domain; Region: A2M_N; pfam01835
585397007263	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cl17457
585397007264	Alpha-2-macroglobulin family; Region: A2M; pfam00207
585397007265	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267
585397007266	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3234
585397007267	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4685
585397007268	DNA gyrase subunit A; Validated; Region: PRK05560
585397007269	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
585397007270	CAP-like domain; other site
585397007271	active site
585397007272	primary dimer interface [polypeptide binding]; other site
585397007273	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
585397007274	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
585397007275	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
585397007276	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
585397007277	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
585397007278	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
585397007279	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
585397007280	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397007281	S-adenosylmethionine binding site [chemical binding]; other site
585397007282	adhesin; Provisional; Region: PRK09752
585397007283	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
585397007284	Autotransporter beta-domain; Region: Autotransporter; pfam03797
585397007285	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
585397007286	ATP cone domain; Region: ATP-cone; pfam03477
585397007287	Class I ribonucleotide reductase; Region: RNR_I; cd01679
585397007288	active site
585397007289	dimer interface [polypeptide binding]; other site
585397007290	catalytic residues [active]
585397007291	effector binding site; other site
585397007292	R2 peptide binding site; other site
585397007293	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
585397007294	dimer interface [polypeptide binding]; other site
585397007295	putative radical transfer pathway; other site
585397007296	diiron center [ion binding]; other site
585397007297	tyrosyl radical; other site
585397007298	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
585397007299	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
585397007300	catalytic loop [active]
585397007301	iron binding site [ion binding]; other site
585397007302	hypothetical protein; Provisional; Region: PRK09902
585397007303	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
585397007304	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
585397007305	active site
585397007306	catalytic site [active]
585397007307	metal binding site [ion binding]; metal-binding site
585397007308	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
585397007309	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397007310	putative substrate translocation pore; other site
585397007311	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
585397007312	hydroxyglutarate oxidase; Provisional; Region: PRK11728
585397007313	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
585397007314	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
585397007315	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
585397007316	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
585397007317	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
585397007318	Cysteine-rich domain; Region: CCG; pfam02754
585397007319	Cysteine-rich domain; Region: CCG; pfam02754
585397007320	hypothetical protein; Provisional; Region: PRK09956
585397007321	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
585397007322	hypothetical protein; Provisional; Region: PRK09956
585397007323	2-keto-3-deoxy-L-rhamnonate aldolase; Provisional; Region: PRK10128
585397007324	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
585397007325	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397007326	putative substrate translocation pore; other site
585397007327	L-rhamnonate dehydratase; Provisional; Region: PRK15440
585397007328	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_2; cd03327
585397007329	putative active site pocket [active]
585397007330	putative metal binding site [ion binding]; other site
585397007331	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
585397007332	Transcriptional regulator [Transcription]; Region: IclR; COG1414
585397007333	Bacterial transcriptional regulator; Region: IclR; pfam01614
585397007334	hypothetical protein; Provisional; Region: PRK03673
585397007335	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
585397007336	putative MPT binding site; other site
585397007337	Competence-damaged protein; Region: CinA; cl00666
585397007338	YfaZ precursor; Region: YfaZ; pfam07437
585397007339	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
585397007340	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
585397007341	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
585397007342	catalytic core [active]
585397007343	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
585397007344	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
585397007345	inhibitor-cofactor binding pocket; inhibition site
585397007346	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397007347	catalytic residue [active]
585397007348	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
585397007349	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
585397007350	Ligand binding site; other site
585397007351	Putative Catalytic site; other site
585397007352	DXD motif; other site
585397007353	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
585397007354	ArnA, N-terminal formyltransferase domain; Region: FMT_core_ArnA_N; cd08644
585397007355	substrate binding site [chemical binding]; other site
585397007356	cosubstrate binding site; other site
585397007357	catalytic site [active]
585397007358	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
585397007359	active site
585397007360	hexamer interface [polypeptide binding]; other site
585397007361	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
585397007362	NAD binding site [chemical binding]; other site
585397007363	substrate binding site [chemical binding]; other site
585397007364	active site
585397007365	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
585397007366	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
585397007367	putative active site [active]
585397007368	putative catalytic site [active]
585397007369	putative Zn binding site [ion binding]; other site
585397007370	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
585397007371	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
585397007372	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
585397007373	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
585397007374	signal transduction protein PmrD; Provisional; Region: PRK15450
585397007375	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
585397007376	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
585397007377	acyl-activating enzyme (AAE) consensus motif; other site
585397007378	putative AMP binding site [chemical binding]; other site
585397007379	putative active site [active]
585397007380	putative CoA binding site [chemical binding]; other site
585397007381	O-succinylbenzoate synthase; Provisional; Region: PRK05105
585397007382	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
585397007383	active site
585397007384	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
585397007385	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
585397007386	substrate binding site [chemical binding]; other site
585397007387	oxyanion hole (OAH) forming residues; other site
585397007388	trimer interface [polypeptide binding]; other site
585397007389	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
585397007390	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
585397007391	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
585397007392	dimer interface [polypeptide binding]; other site
585397007393	tetramer interface [polypeptide binding]; other site
585397007394	PYR/PP interface [polypeptide binding]; other site
585397007395	TPP binding site [chemical binding]; other site
585397007396	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
585397007397	TPP-binding site; other site
585397007398	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
585397007399	isochorismate synthases; Region: isochor_syn; TIGR00543
585397007400	hypothetical protein; Provisional; Region: PRK10404
585397007401	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585397007402	Coenzyme A binding pocket [chemical binding]; other site
585397007403	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
585397007404	von Willebrand factor; Region: vWF_A; pfam12450
585397007405	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
585397007406	VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subgroup; cd01465
585397007407	metal ion-dependent adhesion site (MIDAS); other site
585397007408	Domain of unknown function (DUF3520); Region: DUF3520; pfam12034
585397007409	M28 Zn-Peptidases; Region: M28_like_1; cd05640
585397007410	Peptidase family M28; Region: Peptidase_M28; pfam04389
585397007411	metal binding site [ion binding]; metal-binding site
585397007412	Domain of unknown function (DUF1877); Region: DUF1877; pfam08974
585397007413	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
585397007414	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
585397007415	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
585397007416	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
585397007417	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
585397007418	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
585397007419	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
585397007420	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
585397007421	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
585397007422	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
585397007423	4Fe-4S binding domain; Region: Fer4; pfam00037
585397007424	4Fe-4S binding domain; Region: Fer4; pfam00037
585397007425	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
585397007426	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
585397007427	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
585397007428	catalytic loop [active]
585397007429	iron binding site [ion binding]; other site
585397007430	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
585397007431	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
585397007432	[4Fe-4S] binding site [ion binding]; other site
585397007433	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
585397007434	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
585397007435	SLBB domain; Region: SLBB; pfam10531
585397007436	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
585397007437	NADH dehydrogenase subunit E; Validated; Region: PRK07539
585397007438	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
585397007439	putative dimer interface [polypeptide binding]; other site
585397007440	[2Fe-2S] cluster binding site [ion binding]; other site
585397007441	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
585397007442	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
585397007443	NADH dehydrogenase subunit D; Validated; Region: PRK06075
585397007444	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
585397007445	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
585397007446	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
585397007447	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397007448	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
585397007449	putative dimerization interface [polypeptide binding]; other site
585397007450	aminotransferase AlaT; Validated; Region: PRK09265
585397007451	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585397007452	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397007453	homodimer interface [polypeptide binding]; other site
585397007454	catalytic residue [active]
585397007455	5'-nucleotidase; Provisional; Region: PRK03826
585397007456	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
585397007457	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
585397007458	TrkA-C domain; Region: TrkA_C; pfam02080
585397007459	TrkA-C domain; Region: TrkA_C; pfam02080
585397007460	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
585397007461	putative phosphatase; Provisional; Region: PRK11587
585397007462	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397007463	motif II; other site
585397007464	hypothetical protein; Validated; Region: PRK05445
585397007465	hypothetical protein; Provisional; Region: PRK01816
585397007466	propionate/acetate kinase; Provisional; Region: PRK12379
585397007467	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
585397007468	phosphate acetyltransferase; Reviewed; Region: PRK05632
585397007469	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
585397007470	DRTGG domain; Region: DRTGG; pfam07085
585397007471	phosphate acetyltransferase; Region: pta; TIGR00651
585397007472	hypothetical protein; Provisional; Region: PRK11588
585397007473	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
585397007474	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
585397007475	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
585397007476	nudix motif; other site
585397007477	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
585397007478	active site
585397007479	metal binding site [ion binding]; metal-binding site
585397007480	homotetramer interface [polypeptide binding]; other site
585397007481	glutathione S-transferase; Provisional; Region: PRK15113
585397007482	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
585397007483	C-terminal domain interface [polypeptide binding]; other site
585397007484	GSH binding site (G-site) [chemical binding]; other site
585397007485	dimer interface [polypeptide binding]; other site
585397007486	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
585397007487	N-terminal domain interface [polypeptide binding]; other site
585397007488	putative dimer interface [polypeptide binding]; other site
585397007489	putative substrate binding pocket (H-site) [chemical binding]; other site
585397007490	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
585397007491	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
585397007492	C-terminal domain interface [polypeptide binding]; other site
585397007493	GSH binding site (G-site) [chemical binding]; other site
585397007494	dimer interface [polypeptide binding]; other site
585397007495	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
585397007496	N-terminal domain interface [polypeptide binding]; other site
585397007497	putative dimer interface [polypeptide binding]; other site
585397007498	active site
585397007499	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
585397007500	homooctamer interface [polypeptide binding]; other site
585397007501	active site
585397007502	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
585397007503	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
585397007504	putative NAD(P) binding site [chemical binding]; other site
585397007505	putative active site [active]
585397007506	putative transposase; Provisional; Region: PRK09857
585397007507	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
585397007508	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
585397007509	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
585397007510	Walker A/P-loop; other site
585397007511	ATP binding site [chemical binding]; other site
585397007512	Q-loop/lid; other site
585397007513	ABC transporter signature motif; other site
585397007514	Walker B; other site
585397007515	D-loop; other site
585397007516	H-loop/switch region; other site
585397007517	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397007518	dimer interface [polypeptide binding]; other site
585397007519	conserved gate region; other site
585397007520	putative PBP binding loops; other site
585397007521	ABC-ATPase subunit interface; other site
585397007522	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
585397007523	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397007524	dimer interface [polypeptide binding]; other site
585397007525	conserved gate region; other site
585397007526	putative PBP binding loops; other site
585397007527	ABC-ATPase subunit interface; other site
585397007528	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
585397007529	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585397007530	substrate binding pocket [chemical binding]; other site
585397007531	membrane-bound complex binding site; other site
585397007532	hinge residues; other site
585397007533	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
585397007534	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585397007535	substrate binding pocket [chemical binding]; other site
585397007536	membrane-bound complex binding site; other site
585397007537	hinge residues; other site
585397007538	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
585397007539	Flavoprotein; Region: Flavoprotein; pfam02441
585397007540	amidophosphoribosyltransferase; Provisional; Region: PRK09246
585397007541	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
585397007542	active site
585397007543	tetramer interface [polypeptide binding]; other site
585397007544	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
585397007545	active site
585397007546	colicin V production protein; Provisional; Region: PRK10845
585397007547	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
585397007548	cell division protein DedD; Provisional; Region: PRK11633
585397007549	Sporulation related domain; Region: SPOR; pfam05036
585397007550	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
585397007551	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
585397007552	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
585397007553	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
585397007554	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
585397007555	hypothetical protein; Provisional; Region: PRK10847
585397007556	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
585397007557	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
585397007558	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
585397007559	dimerization interface 3.5A [polypeptide binding]; other site
585397007560	active site
585397007561	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
585397007562	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
585397007563	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
585397007564	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
585397007565	ligand binding site [chemical binding]; other site
585397007566	NAD binding site [chemical binding]; other site
585397007567	catalytic site [active]
585397007568	homodimer interface [polypeptide binding]; other site
585397007569	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
585397007570	putative transporter; Provisional; Region: PRK12382
585397007571	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397007572	putative substrate translocation pore; other site
585397007573	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
585397007574	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
585397007575	dimer interface [polypeptide binding]; other site
585397007576	active site
585397007577	Uncharacterized conserved protein [Function unknown]; Region: COG4121
585397007578	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
585397007579	YfcL protein; Region: YfcL; pfam08891
585397007580	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
585397007581	hypothetical protein; Provisional; Region: PRK10621
585397007582	Predicted permeases [General function prediction only]; Region: COG0730
585397007583	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
585397007584	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
585397007585	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
585397007586	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
585397007587	Tetramer interface [polypeptide binding]; other site
585397007588	active site
585397007589	FMN-binding site [chemical binding]; other site
585397007590	HemK family putative methylases; Region: hemK_fam; TIGR00536
585397007591	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397007592	S-adenosylmethionine binding site [chemical binding]; other site
585397007593	hypothetical protein; Provisional; Region: PRK04946
585397007594	Smr domain; Region: Smr; pfam01713
585397007595	Protein of unknown function (DUF2544); Region: DUF2544; pfam11245
585397007596	Fimbrial protein; Region: Fimbrial; cl01416
585397007597	Fimbrial protein; Region: Fimbrial; cl01416
585397007598	Fimbrial protein; Region: Fimbrial; cl01416
585397007599	putative fimbrial chaperone protein StfD; Provisional; Region: PRK15285
585397007600	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585397007601	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
585397007602	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
585397007603	PapC N-terminal domain; Region: PapC_N; pfam13954
585397007604	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585397007605	PapC C-terminal domain; Region: PapC_C; pfam13953
585397007606	Fimbrial protein; Region: Fimbrial; cl01416
585397007607	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
585397007608	catalytic core [active]
585397007609	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
585397007610	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
585397007611	substrate binding site [chemical binding]; other site
585397007612	oxyanion hole (OAH) forming residues; other site
585397007613	trimer interface [polypeptide binding]; other site
585397007614	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
585397007615	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
585397007616	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
585397007617	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
585397007618	dimer interface [polypeptide binding]; other site
585397007619	active site
585397007620	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
585397007621	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
585397007622	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
585397007623	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
585397007624	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
585397007625	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397007626	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
585397007627	dimerization interface [polypeptide binding]; other site
585397007628	substrate binding pocket [chemical binding]; other site
585397007629	permease DsdX; Provisional; Region: PRK09921
585397007630	gluconate transporter; Region: gntP; TIGR00791
585397007631	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
585397007632	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
585397007633	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
585397007634	catalytic residue [active]
585397007635	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
585397007636	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397007637	putative substrate translocation pore; other site
585397007638	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397007639	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
585397007640	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585397007641	HlyD family secretion protein; Region: HlyD_3; pfam13437
585397007642	DNA-binding transcriptional activator EvgA; Provisional; Region: PRK09958
585397007643	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397007644	active site
585397007645	phosphorylation site [posttranslational modification]
585397007646	intermolecular recognition site; other site
585397007647	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585397007648	DNA binding residues [nucleotide binding]
585397007649	dimerization interface [polypeptide binding]; other site
585397007650	hybrid sensory histidine kinase in two-component regulatory system with EvgA; Provisional; Region: PRK09959
585397007651	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585397007652	substrate binding pocket [chemical binding]; other site
585397007653	membrane-bound complex binding site; other site
585397007654	hinge residues; other site
585397007655	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585397007656	substrate binding pocket [chemical binding]; other site
585397007657	membrane-bound complex binding site; other site
585397007658	hinge residues; other site
585397007659	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585397007660	dimer interface [polypeptide binding]; other site
585397007661	phosphorylation site [posttranslational modification]
585397007662	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397007663	ATP binding site [chemical binding]; other site
585397007664	Mg2+ binding site [ion binding]; other site
585397007665	G-X-G motif; other site
585397007666	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397007667	active site
585397007668	phosphorylation site [posttranslational modification]
585397007669	intermolecular recognition site; other site
585397007670	dimerization interface [polypeptide binding]; other site
585397007671	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
585397007672	putative binding surface; other site
585397007673	active site
585397007674	putative CoA-transferase; Provisional; Region: PRK11430
585397007675	CoA-transferase family III; Region: CoA_transf_3; pfam02515
585397007676	putative transporter YfdV; Provisional; Region: PRK09903
585397007677	putative oxalyl-CoA decarboxylase; Validated; Region: PRK09259
585397007678	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
585397007679	PYR/PP interface [polypeptide binding]; other site
585397007680	dimer interface [polypeptide binding]; other site
585397007681	TPP binding site [chemical binding]; other site
585397007682	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
585397007683	Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL...; Region: TPP_BZL_OCoD_HPCL; cd02004
585397007684	TPP-binding site; other site
585397007685	dimer interface [polypeptide binding]; other site
585397007686	formyl-coenzyme A transferase; Provisional; Region: PRK05398
585397007687	CoA-transferase family III; Region: CoA_transf_3; pfam02515
585397007688	hypothetical protein; Provisional; Region: PRK10316
585397007689	YfdX protein; Region: YfdX; pfam10938
585397007690	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
585397007691	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
585397007692	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
585397007693	putative acyl-acceptor binding pocket; other site
585397007694	aminotransferase; Validated; Region: PRK08175
585397007695	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585397007696	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397007697	homodimer interface [polypeptide binding]; other site
585397007698	catalytic residue [active]
585397007699	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
585397007700	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
585397007701	GAF domain; Region: GAF; cl17456
585397007702	Histidine kinase; Region: His_kinase; pfam06580
585397007703	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397007704	ATP binding site [chemical binding]; other site
585397007705	Mg2+ binding site [ion binding]; other site
585397007706	G-X-G motif; other site
585397007707	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
585397007708	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397007709	active site
585397007710	phosphorylation site [posttranslational modification]
585397007711	intermolecular recognition site; other site
585397007712	dimerization interface [polypeptide binding]; other site
585397007713	LytTr DNA-binding domain; Region: LytTR; pfam04397
585397007714	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
585397007715	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397007716	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
585397007717	dimerization domain swap beta strand [polypeptide binding]; other site
585397007718	regulatory protein interface [polypeptide binding]; other site
585397007719	active site
585397007720	regulatory phosphorylation site [posttranslational modification]; other site
585397007721	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
585397007722	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
585397007723	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
585397007724	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
585397007725	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
585397007726	active site
585397007727	phosphorylation site [posttranslational modification]
585397007728	exoaminopeptidase; Provisional; Region: PRK09961
585397007729	M42 Peptidases, also known as glutamyl aminopeptidase family; Region: M42; cd05638
585397007730	oligomer interface [polypeptide binding]; other site
585397007731	active site
585397007732	metal binding site [ion binding]; metal-binding site
585397007733	aminopeptidase; Provisional; Region: PRK09795
585397007734	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
585397007735	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
585397007736	active site
585397007737	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
585397007738	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
585397007739	active site
585397007740	P-loop; other site
585397007741	phosphorylation site [posttranslational modification]
585397007742	glucokinase, proteobacterial type; Region: glk; TIGR00749
585397007743	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
585397007744	nucleotide binding site [chemical binding]; other site
585397007745	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
585397007746	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
585397007747	Cl- selectivity filter; other site
585397007748	Cl- binding residues [ion binding]; other site
585397007749	pore gating glutamate residue; other site
585397007750	dimer interface [polypeptide binding]; other site
585397007751	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
585397007752	manganese transport protein MntH; Reviewed; Region: PRK00701
585397007753	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
585397007754	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
585397007755	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
585397007756	Nucleoside recognition; Region: Gate; pfam07670
585397007757	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
585397007758	fragment of putative diguanylate cyclase (part 2);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397007759	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
585397007760	Transposase; Region: HTH_Tnp_1; pfam01527
585397007761	putative transposase OrfB; Reviewed; Region: PHA02517
585397007762	Integrase core domain; Region: rve; pfam00665
585397007763	Integrase core domain; Region: rve_3; pfam13683
585397007764	fragment of putative diguanylate cyclase (part 1);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397007765	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
585397007766	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397007767	salt bridge; other site
585397007768	non-specific DNA binding site [nucleotide binding]; other site
585397007769	sequence-specific DNA binding site [nucleotide binding]; other site
585397007770	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
585397007771	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
585397007772	active site
585397007773	HIGH motif; other site
585397007774	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
585397007775	active site
585397007776	KMSKS motif; other site
585397007777	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
585397007778	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397007779	The C-terminal substrate binding domain of LysR-type transcriptional regulator XapR involved in xanthosine catabolism, contains the type 2 periplasmic binding fold; Region: PBP2_XapR; cd08449
585397007780	putative dimerization interface [polypeptide binding]; other site
585397007781	putative substrate binding pocket [chemical binding]; other site
585397007782	nucleoside transporter; Region: 2A0110; TIGR00889
585397007783	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397007784	putative substrate translocation pore; other site
585397007785	purine nucleoside phosphorylase; Provisional; Region: PRK08202
585397007786	hypothetical protein; Provisional; Region: PRK11528
585397007787	Transcriptional regulator [Transcription]; Region: LysR; COG0583
585397007788	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397007789	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
585397007790	putative dimerization interface [polypeptide binding]; other site
585397007791	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
585397007792	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
585397007793	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
585397007794	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
585397007795	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
585397007796	nucleotide binding pocket [chemical binding]; other site
585397007797	K-X-D-G motif; other site
585397007798	catalytic site [active]
585397007799	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
585397007800	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
585397007801	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
585397007802	Dimer interface [polypeptide binding]; other site
585397007803	BRCT sequence motif; other site
585397007804	cell division protein ZipA; Provisional; Region: PRK03427
585397007805	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
585397007806	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
585397007807	FtsZ protein binding site [polypeptide binding]; other site
585397007808	putative sulfate transport protein CysZ; Validated; Region: PRK04949
585397007809	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
585397007810	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
585397007811	dimer interface [polypeptide binding]; other site
585397007812	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397007813	catalytic residue [active]
585397007814	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
585397007815	dimerization domain swap beta strand [polypeptide binding]; other site
585397007816	regulatory protein interface [polypeptide binding]; other site
585397007817	active site
585397007818	regulatory phosphorylation site [posttranslational modification]; other site
585397007819	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
585397007820	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
585397007821	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
585397007822	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
585397007823	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
585397007824	HPr interaction site; other site
585397007825	glycerol kinase (GK) interaction site [polypeptide binding]; other site
585397007826	active site
585397007827	phosphorylation site [posttranslational modification]
585397007828	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
585397007829	dimer interface [polypeptide binding]; other site
585397007830	pyridoxamine kinase; Validated; Region: PRK05756
585397007831	pyridoxal binding site [chemical binding]; other site
585397007832	ATP binding site [chemical binding]; other site
585397007833	hypothetical protein; Provisional; Region: PRK10318
585397007834	cysteine synthase B; Region: cysM; TIGR01138
585397007835	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
585397007836	dimer interface [polypeptide binding]; other site
585397007837	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397007838	catalytic residue [active]
585397007839	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
585397007840	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
585397007841	Walker A/P-loop; other site
585397007842	ATP binding site [chemical binding]; other site
585397007843	Q-loop/lid; other site
585397007844	ABC transporter signature motif; other site
585397007845	Walker B; other site
585397007846	D-loop; other site
585397007847	H-loop/switch region; other site
585397007848	TOBE-like domain; Region: TOBE_3; pfam12857
585397007849	sulfate transport protein; Provisional; Region: cysT; CHL00187
585397007850	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397007851	dimer interface [polypeptide binding]; other site
585397007852	conserved gate region; other site
585397007853	putative PBP binding loops; other site
585397007854	ABC-ATPase subunit interface; other site
585397007855	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
585397007856	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397007857	dimer interface [polypeptide binding]; other site
585397007858	conserved gate region; other site
585397007859	putative PBP binding loops; other site
585397007860	ABC-ATPase subunit interface; other site
585397007861	thiosulfate transporter subunit; Provisional; Region: PRK10852
585397007862	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
585397007863	short chain dehydrogenase; Provisional; Region: PRK08226
585397007864	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
585397007865	NAD binding site [chemical binding]; other site
585397007866	homotetramer interface [polypeptide binding]; other site
585397007867	homodimer interface [polypeptide binding]; other site
585397007868	active site
585397007869	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
585397007870	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
585397007871	putative active site [active]
585397007872	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
585397007873	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
585397007874	active site turn [active]
585397007875	phosphorylation site [posttranslational modification]
585397007876	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
585397007877	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
585397007878	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
585397007879	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
585397007880	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
585397007881	putative acetyltransferase; Provisional; Region: PRK03624
585397007882	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585397007883	Coenzyme A binding pocket [chemical binding]; other site
585397007884	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
585397007885	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
585397007886	active site
585397007887	metal binding site [ion binding]; metal-binding site
585397007888	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
585397007889	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
585397007890	transcriptional regulator EutR; Provisional; Region: PRK10130
585397007891	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397007892	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397007893	carboxysome structural protein EutK; Provisional; Region: PRK15466
585397007894	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
585397007895	Hexamer interface [polypeptide binding]; other site
585397007896	Hexagonal pore residue; other site
585397007897	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
585397007898	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
585397007899	putative hexamer interface [polypeptide binding]; other site
585397007900	putative hexagonal pore; other site
585397007901	Bacterial Micro-Compartment (BMC) domain; Region: BMC; cl01982
585397007902	Hexamer interface [polypeptide binding]; other site
585397007903	Hexagonal pore residue; other site
585397007904	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
585397007905	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
585397007906	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
585397007907	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
585397007908	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
585397007909	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
585397007910	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
585397007911	active site
585397007912	metal binding site [ion binding]; metal-binding site
585397007913	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
585397007914	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
585397007915	nucleotide binding site [chemical binding]; other site
585397007916	aldehyde dehydrogenase EutE; Provisional; Region: PRK15398
585397007917	NAD(P) binding site [chemical binding]; other site
585397007918	catalytic residues [active]
585397007919	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
585397007920	Hexamer/Pentamer interface [polypeptide binding]; other site
585397007921	central pore; other site
585397007922	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
585397007923	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
585397007924	Hexamer interface [polypeptide binding]; other site
585397007925	Putative hexagonal pore residue; other site
585397007926	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
585397007927	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
585397007928	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
585397007929	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
585397007930	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
585397007931	G1 box; other site
585397007932	GTP/Mg2+ binding site [chemical binding]; other site
585397007933	G2 box; other site
585397007934	Switch I region; other site
585397007935	G3 box; other site
585397007936	Switch II region; other site
585397007937	G4 box; other site
585397007938	G5 box; other site
585397007939	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
585397007940	putative hexamer interface [polypeptide binding]; other site
585397007941	putative hexagonal pore; other site
585397007942	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
585397007943	Malic enzyme, N-terminal domain; Region: malic; pfam00390
585397007944	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
585397007945	putative NAD(P) binding site [chemical binding]; other site
585397007946	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
585397007947	transaldolase-like protein; Provisional; Region: PTZ00411
585397007948	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
585397007949	active site
585397007950	dimer interface [polypeptide binding]; other site
585397007951	catalytic residue [active]
585397007952	transketolase; Reviewed; Region: PRK12753
585397007953	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
585397007954	TPP-binding site [chemical binding]; other site
585397007955	dimer interface [polypeptide binding]; other site
585397007956	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
585397007957	PYR/PP interface [polypeptide binding]; other site
585397007958	dimer interface [polypeptide binding]; other site
585397007959	TPP binding site [chemical binding]; other site
585397007960	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
585397007961	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
585397007962	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
585397007963	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
585397007964	dimer interface [polypeptide binding]; other site
585397007965	ADP-ribose binding site [chemical binding]; other site
585397007966	active site
585397007967	nudix motif; other site
585397007968	metal binding site [ion binding]; metal-binding site
585397007969	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
585397007970	4Fe-4S binding domain; Region: Fer4; pfam00037
585397007971	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
585397007972	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585397007973	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
585397007974	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
585397007975	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585397007976	dimerization interface [polypeptide binding]; other site
585397007977	Histidine kinase; Region: HisKA_3; pfam07730
585397007978	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397007979	ATP binding site [chemical binding]; other site
585397007980	Mg2+ binding site [ion binding]; other site
585397007981	G-X-G motif; other site
585397007982	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
585397007983	Protein export membrane protein; Region: SecD_SecF; cl14618
585397007984	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
585397007985	ArsC family; Region: ArsC; pfam03960
585397007986	putative catalytic residues [active]
585397007987	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
585397007988	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
585397007989	metal binding site [ion binding]; metal-binding site
585397007990	dimer interface [polypeptide binding]; other site
585397007991	hypothetical protein; Provisional; Region: PRK13664
585397007992	putative hydrolase; Provisional; Region: PRK11460
585397007993	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
585397007994	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
585397007995	Helicase; Region: Helicase_RecD; pfam05127
585397007996	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
585397007997	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
585397007998	Predicted metalloprotease [General function prediction only]; Region: COG2321
585397007999	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
585397008000	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
585397008001	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
585397008002	ATP binding site [chemical binding]; other site
585397008003	active site
585397008004	substrate binding site [chemical binding]; other site
585397008005	lipoprotein; Provisional; Region: PRK11679
585397008006	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
585397008007	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
585397008008	dihydrodipicolinate synthase; Region: dapA; TIGR00674
585397008009	dimer interface [polypeptide binding]; other site
585397008010	active site
585397008011	catalytic residue [active]
585397008012	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
585397008013	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
585397008014	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
585397008015	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
585397008016	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
585397008017	catalytic triad [active]
585397008018	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
585397008019	Domain of unknown function DUF20; Region: UPF0118; pfam01594
585397008020	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
585397008021	Peptidase family M48; Region: Peptidase_M48; cl12018
585397008022	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
585397008023	ArsC family; Region: ArsC; pfam03960
585397008024	catalytic residues [active]
585397008025	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
585397008026	DNA replication initiation factor; Provisional; Region: PRK08084
585397008027	uracil transporter; Provisional; Region: PRK10720
585397008028	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
585397008029	active site
585397008030	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
585397008031	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
585397008032	dimerization interface [polypeptide binding]; other site
585397008033	putative ATP binding site [chemical binding]; other site
585397008034	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
585397008035	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
585397008036	active site
585397008037	substrate binding site [chemical binding]; other site
585397008038	cosubstrate binding site; other site
585397008039	catalytic site [active]
585397008040	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
585397008041	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
585397008042	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
585397008043	Catalytic C-terminal domain, first repeat, of prokaryotic polyphosphate kinase 1 and similar proteins; Region: PLDc_PPK1_C1; cd09114
585397008044	domain interface [polypeptide binding]; other site
585397008045	active site
585397008046	catalytic site [active]
585397008047	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
585397008048	domain interface [polypeptide binding]; other site
585397008049	active site
585397008050	catalytic site [active]
585397008051	exopolyphosphatase; Provisional; Region: PRK10854
585397008052	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
585397008053	MASE1; Region: MASE1; pfam05231
585397008054	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
585397008055	diguanylate cyclase; Region: GGDEF; smart00267
585397008056	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585397008057	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
585397008058	GMP synthase; Reviewed; Region: guaA; PRK00074
585397008059	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
585397008060	AMP/PPi binding site [chemical binding]; other site
585397008061	candidate oxyanion hole; other site
585397008062	catalytic triad [active]
585397008063	potential glutamine specificity residues [chemical binding]; other site
585397008064	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
585397008065	ATP Binding subdomain [chemical binding]; other site
585397008066	Ligand Binding sites [chemical binding]; other site
585397008067	Dimerization subdomain; other site
585397008068	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
585397008069	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
585397008070	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
585397008071	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
585397008072	active site
585397008073	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
585397008074	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
585397008075	generic binding surface II; other site
585397008076	generic binding surface I; other site
585397008077	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
585397008078	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397008079	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397008080	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397008081	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397008082	fragment of putative outer membrane protein; RatA precursor homolog (part 2);Evidence 7 : Gene remnant; Product type pm : putative membrane component
585397008083	fragment of putative outer membrane protein; RatA precursor homolog (part 1);Evidence 7 : Gene remnant; Product type pm : putative membrane component
585397008084	intimin-like protein SinH; Provisional; Region: PRK15318
585397008085	intimin-like protein SinH; Provisional; Region: PRK15318
585397008086	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
585397008087	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
585397008088	GTP-binding protein Der; Reviewed; Region: PRK00093
585397008089	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
585397008090	G1 box; other site
585397008091	GTP/Mg2+ binding site [chemical binding]; other site
585397008092	Switch I region; other site
585397008093	G2 box; other site
585397008094	Switch II region; other site
585397008095	G3 box; other site
585397008096	G4 box; other site
585397008097	G5 box; other site
585397008098	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
585397008099	G1 box; other site
585397008100	GTP/Mg2+ binding site [chemical binding]; other site
585397008101	Switch I region; other site
585397008102	G2 box; other site
585397008103	G3 box; other site
585397008104	Switch II region; other site
585397008105	G4 box; other site
585397008106	G5 box; other site
585397008107	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
585397008108	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cd00216
585397008109	Trp docking motif [polypeptide binding]; other site
585397008110	active site
585397008111	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
585397008112	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
585397008113	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
585397008114	dimer interface [polypeptide binding]; other site
585397008115	motif 1; other site
585397008116	active site
585397008117	motif 2; other site
585397008118	motif 3; other site
585397008119	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
585397008120	anticodon binding site; other site
585397008121	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
585397008122	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
585397008123	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
585397008124	cytoskeletal protein RodZ; Provisional; Region: PRK10856
585397008125	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397008126	non-specific DNA binding site [nucleotide binding]; other site
585397008127	salt bridge; other site
585397008128	sequence-specific DNA binding site [nucleotide binding]; other site
585397008129	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
585397008130	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
585397008131	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585397008132	FeS/SAM binding site; other site
585397008133	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
585397008134	active site
585397008135	multimer interface [polypeptide binding]; other site
585397008136	penicillin-binding protein 1C; Provisional; Region: PRK11240
585397008137	Transglycosylase; Region: Transgly; pfam00912
585397008138	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
585397008139	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
585397008140	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
585397008141	MG2 domain; Region: A2M_N; pfam01835
585397008142	Alpha-2-macroglobulin family; Region: A2M; pfam00207
585397008143	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
585397008144	surface patch; other site
585397008145	thioester region; other site
585397008146	specificity defining residues; other site
585397008147	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
585397008148	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
585397008149	active site residue [active]
585397008150	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
585397008151	active site residue [active]
585397008152	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
585397008153	aminopeptidase B; Provisional; Region: PRK05015
585397008154	Peptidase; Region: DUF3663; pfam12404
585397008155	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
585397008156	interface (dimer of trimers) [polypeptide binding]; other site
585397008157	Substrate-binding/catalytic site; other site
585397008158	Zn-binding sites [ion binding]; other site
585397008159	hypothetical protein; Provisional; Region: PRK10721
585397008160	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
585397008161	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
585397008162	catalytic loop [active]
585397008163	iron binding site [ion binding]; other site
585397008164	chaperone protein HscA; Provisional; Region: hscA; PRK05183
585397008165	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
585397008166	nucleotide binding site [chemical binding]; other site
585397008167	putative NEF/HSP70 interaction site [polypeptide binding]; other site
585397008168	SBD interface [polypeptide binding]; other site
585397008169	co-chaperone HscB; Provisional; Region: hscB; PRK05014
585397008170	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
585397008171	HSP70 interaction site [polypeptide binding]; other site
585397008172	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
585397008173	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
585397008174	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
585397008175	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
585397008176	trimerization site [polypeptide binding]; other site
585397008177	active site
585397008178	cysteine desulfurase; Provisional; Region: PRK14012
585397008179	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
585397008180	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
585397008181	catalytic residue [active]
585397008182	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
585397008183	Rrf2 family protein; Region: rrf2_super; TIGR00738
585397008184	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
585397008185	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
585397008186	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
585397008187	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
585397008188	active site
585397008189	dimerization interface [polypeptide binding]; other site
585397008190	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
585397008191	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
585397008192	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
585397008193	PRD domain; Region: PRD; pfam00874
585397008194	PRD domain; Region: PRD; pfam00874
585397008195	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
585397008196	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397008197	putative substrate translocation pore; other site
585397008198	Predicted membrane protein [Function unknown]; Region: COG2259
585397008199	aldose 1-epimerase, similar to Escherichia coli YphB; Region: Aldose_epim_Ec_YphB; cd09021
585397008200	active site
585397008201	catalytic residues [active]
585397008202	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
585397008203	L-threonine dehydrogenase (TDH)-like; Region: THR_DH_like; cd08239
585397008204	putative NAD(P) binding site [chemical binding]; other site
585397008205	catalytic Zn binding site [ion binding]; other site
585397008206	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585397008207	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585397008208	TM-ABC transporter signature motif; other site
585397008209	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
585397008210	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
585397008211	Walker A/P-loop; other site
585397008212	ATP binding site [chemical binding]; other site
585397008213	Q-loop/lid; other site
585397008214	ABC transporter signature motif; other site
585397008215	Walker B; other site
585397008216	D-loop; other site
585397008217	H-loop/switch region; other site
585397008218	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
585397008219	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
585397008220	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
585397008221	ligand binding site [chemical binding]; other site
585397008222	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585397008223	TPR motif; other site
585397008224	Tetratricopeptide repeat; Region: TPR_16; pfam13432
585397008225	binding surface
585397008226	TPR repeat; Region: TPR_11; pfam13414
585397008227	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585397008228	TPR motif; other site
585397008229	binding surface
585397008230	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
585397008231	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
585397008232	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
585397008233	nucleotide binding site [chemical binding]; other site
585397008234	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
585397008235	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
585397008236	dimer interface [polypeptide binding]; other site
585397008237	active site
585397008238	glycine-pyridoxal phosphate binding site [chemical binding]; other site
585397008239	folate binding site [chemical binding]; other site
585397008240	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
585397008241	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
585397008242	heme-binding site [chemical binding]; other site
585397008243	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
585397008244	FAD binding pocket [chemical binding]; other site
585397008245	FAD binding motif [chemical binding]; other site
585397008246	phosphate binding motif [ion binding]; other site
585397008247	beta-alpha-beta structure motif; other site
585397008248	NAD binding pocket [chemical binding]; other site
585397008249	Heme binding  pocket [chemical binding]; other site
585397008250	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
585397008251	Nitrogen regulatory protein P-II; Region: P-II; smart00938
585397008252	response regulator GlrR; Provisional; Region: PRK15115
585397008253	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397008254	active site
585397008255	phosphorylation site [posttranslational modification]
585397008256	intermolecular recognition site; other site
585397008257	dimerization interface [polypeptide binding]; other site
585397008258	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397008259	Walker A motif; other site
585397008260	ATP binding site [chemical binding]; other site
585397008261	Walker B motif; other site
585397008262	arginine finger; other site
585397008263	hypothetical protein; Provisional; Region: PRK10722
585397008264	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
585397008265	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585397008266	dimer interface [polypeptide binding]; other site
585397008267	phosphorylation site [posttranslational modification]
585397008268	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397008269	ATP binding site [chemical binding]; other site
585397008270	Mg2+ binding site [ion binding]; other site
585397008271	G-X-G motif; other site
585397008272	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
585397008273	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
585397008274	dimerization interface [polypeptide binding]; other site
585397008275	ATP binding site [chemical binding]; other site
585397008276	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
585397008277	dimerization interface [polypeptide binding]; other site
585397008278	ATP binding site [chemical binding]; other site
585397008279	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
585397008280	putative active site [active]
585397008281	catalytic triad [active]
585397008282	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
585397008283	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585397008284	substrate binding pocket [chemical binding]; other site
585397008285	membrane-bound complex binding site; other site
585397008286	hinge residues; other site
585397008287	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
585397008288	N-acetyl-D-glucosamine binding site [chemical binding]; other site
585397008289	catalytic residue [active]
585397008290	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
585397008291	nucleoside/Zn binding site; other site
585397008292	dimer interface [polypeptide binding]; other site
585397008293	catalytic motif [active]
585397008294	hypothetical protein; Provisional; Region: PRK11590
585397008295	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
585397008296	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
585397008297	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
585397008298	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
585397008299	putative active site [active]
585397008300	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
585397008301	holo-[acyl-carrier-protein] synthase; Region: acpS; TIGR00516
585397008302	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
585397008303	active site
585397008304	hydrophilic channel; other site
585397008305	dimerization interface [polypeptide binding]; other site
585397008306	catalytic residues [active]
585397008307	active site lid [active]
585397008308	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
585397008309	Recombination protein O N terminal; Region: RecO_N; pfam11967
585397008310	Recombination protein O C terminal; Region: RecO_C; pfam02565
585397008311	GTPase Era; Reviewed; Region: era; PRK00089
585397008312	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
585397008313	G1 box; other site
585397008314	GTP/Mg2+ binding site [chemical binding]; other site
585397008315	Switch I region; other site
585397008316	G2 box; other site
585397008317	Switch II region; other site
585397008318	G3 box; other site
585397008319	G4 box; other site
585397008320	G5 box; other site
585397008321	KH domain; Region: KH_2; pfam07650
585397008322	ribonuclease III; Reviewed; Region: rnc; PRK00102
585397008323	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
585397008324	dimerization interface [polypeptide binding]; other site
585397008325	active site
585397008326	metal binding site [ion binding]; metal-binding site
585397008327	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
585397008328	dsRNA binding site [nucleotide binding]; other site
585397008329	signal peptidase I; Provisional; Region: PRK10861
585397008330	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
585397008331	Catalytic site [active]
585397008332	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
585397008333	GTP-binding protein LepA; Provisional; Region: PRK05433
585397008334	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
585397008335	G1 box; other site
585397008336	putative GEF interaction site [polypeptide binding]; other site
585397008337	GTP/Mg2+ binding site [chemical binding]; other site
585397008338	Switch I region; other site
585397008339	G2 box; other site
585397008340	G3 box; other site
585397008341	Switch II region; other site
585397008342	G4 box; other site
585397008343	G5 box; other site
585397008344	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
585397008345	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
585397008346	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
585397008347	SoxR reducing system protein RseC; Provisional; Region: PRK10862
585397008348	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
585397008349	anti-sigma E factor; Provisional; Region: rseB; PRK09455
585397008350	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
585397008351	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
585397008352	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
585397008353	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
585397008354	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
585397008355	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
585397008356	DNA binding residues [nucleotide binding]
585397008357	L-aspartate oxidase; Provisional; Region: PRK09077
585397008358	L-aspartate oxidase; Provisional; Region: PRK06175
585397008359	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
585397008360	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
585397008361	Methyltransferase domain; Region: Methyltransf_26; pfam13659
585397008362	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
585397008363	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
585397008364	ATP binding site [chemical binding]; other site
585397008365	Mg++ binding site [ion binding]; other site
585397008366	motif III; other site
585397008367	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585397008368	nucleotide binding region [chemical binding]; other site
585397008369	ATP-binding site [chemical binding]; other site
585397008370	Transcriptional regulator [Transcription]; Region: LysR; COG0583
585397008371	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397008372	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
585397008373	dimerization interface [polypeptide binding]; other site
585397008374	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
585397008375	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
585397008376	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
585397008377	ligand binding site [chemical binding]; other site
585397008378	active site
585397008379	UGI interface [polypeptide binding]; other site
585397008380	catalytic site [active]
585397008381	putative methyltransferase; Provisional; Region: PRK10864
585397008382	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
585397008383	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
585397008384	thioredoxin 2; Provisional; Region: PRK10996
585397008385	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
585397008386	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
585397008387	catalytic residues [active]
585397008388	Uncharacterized conserved protein [Function unknown]; Region: COG3148
585397008389	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
585397008390	CoA binding domain; Region: CoA_binding_2; pfam13380
585397008391	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
585397008392	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
585397008393	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
585397008394	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
585397008395	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
585397008396	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
585397008397	domain interface [polypeptide binding]; other site
585397008398	putative active site [active]
585397008399	catalytic site [active]
585397008400	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
585397008401	domain interface [polypeptide binding]; other site
585397008402	putative active site [active]
585397008403	catalytic site [active]
585397008404	lipoprotein; Provisional; Region: PRK10759
585397008405	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
585397008406	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397008407	putative substrate translocation pore; other site
585397008408	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397008409	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397008410	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397008411	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397008412	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
585397008413	Transposase; Region: DEDD_Tnp_IS110; pfam01548
585397008414	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
585397008415	Transposase; Region: DEDD_Tnp_IS110; pfam01548
585397008416	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
585397008417	HTH-like domain; Region: HTH_21; pfam13276
585397008418	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
585397008419	Integrase core domain; Region: rve; pfam00665
585397008420	Integrase core domain; Region: rve_2; pfam13333
585397008421	fragment of transposase ORF A, IS1397 (partial);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397008422	protein disaggregation chaperone; Provisional; Region: PRK10865
585397008423	Clp amino terminal domain; Region: Clp_N; pfam02861
585397008424	Clp amino terminal domain; Region: Clp_N; pfam02861
585397008425	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397008426	Walker A motif; other site
585397008427	ATP binding site [chemical binding]; other site
585397008428	Walker B motif; other site
585397008429	arginine finger; other site
585397008430	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397008431	Walker A motif; other site
585397008432	ATP binding site [chemical binding]; other site
585397008433	Walker B motif; other site
585397008434	arginine finger; other site
585397008435	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
585397008436	hypothetical protein; Provisional; Region: PRK10723
585397008437	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
585397008438	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
585397008439	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
585397008440	RNA binding surface [nucleotide binding]; other site
585397008441	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
585397008442	active site
585397008443	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
585397008444	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
585397008445	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
585397008446	30S subunit binding site; other site
585397008447	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
585397008448	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
585397008449	Prephenate dehydratase; Region: PDT; pfam00800
585397008450	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
585397008451	putative L-Phe binding site [chemical binding]; other site
585397008452	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
585397008453	chorismate mutase domain of T-protein; Region: CM_T; TIGR01799
585397008454	prephenate dehydrogenase; Validated; Region: PRK08507
585397008455	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
585397008456	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
585397008457	lipoprotein; Provisional; Region: PRK11443
585397008458	Protein of unknown function (DUF2799); Region: DUF2799; pfam10973
585397008459	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
585397008460	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
585397008461	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585397008462	metal binding site [ion binding]; metal-binding site
585397008463	active site
585397008464	I-site; other site
585397008465	putative outer membrane lipoprotein; Provisional; Region: PRK09967
585397008466	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
585397008467	ligand binding site [chemical binding]; other site
585397008468	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
585397008469	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
585397008470	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
585397008471	RimM N-terminal domain; Region: RimM; pfam01782
585397008472	PRC-barrel domain; Region: PRC; pfam05239
585397008473	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
585397008474	signal recognition particle protein; Provisional; Region: PRK10867
585397008475	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
585397008476	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
585397008477	P loop; other site
585397008478	GTP binding site [chemical binding]; other site
585397008479	Signal peptide binding domain; Region: SRP_SPB; pfam02978
585397008480	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
585397008481	hypothetical protein; Provisional; Region: PRK11573
585397008482	Domain of unknown function DUF21; Region: DUF21; pfam01595
585397008483	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
585397008484	Transporter associated domain; Region: CorC_HlyC; smart01091
585397008485	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
585397008486	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
585397008487	dimer interface [polypeptide binding]; other site
585397008488	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
585397008489	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
585397008490	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
585397008491	recombination and repair protein; Provisional; Region: PRK10869
585397008492	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
585397008493	Walker A/P-loop; other site
585397008494	ATP binding site [chemical binding]; other site
585397008495	Q-loop/lid; other site
585397008496	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
585397008497	Q-loop/lid; other site
585397008498	ABC transporter signature motif; other site
585397008499	Walker B; other site
585397008500	D-loop; other site
585397008501	H-loop/switch region; other site
585397008502	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
585397008503	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
585397008504	hypothetical protein; Validated; Region: PRK01777
585397008505	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
585397008506	putative coenzyme Q binding site [chemical binding]; other site
585397008507	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
585397008508	SmpB-tmRNA interface; other site
585397008509	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cl00038
585397008510	tail protein; Provisional; Region: D; PHA02561
585397008511	Phage protein U [General function prediction only]; Region: COG3499
585397008512	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
585397008513	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
585397008514	major tail tube protein; Provisional; Region: FII; PHA02600
585397008515	major tail sheath protein; Provisional; Region: FI; PHA02560
585397008516	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
585397008517	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
585397008518	catalytic residues [active]
585397008519	catalytic nucleophile [active]
585397008520	Presynaptic Site I dimer interface [polypeptide binding]; other site
585397008521	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
585397008522	Synaptic Flat tetramer interface [polypeptide binding]; other site
585397008523	Synaptic Site I dimer interface [polypeptide binding]; other site
585397008524	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
585397008525	DNA-binding interface [nucleotide binding]; DNA binding site
585397008526	Phage Tail Collar Domain; Region: Collar; pfam07484
585397008527	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
585397008528	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
585397008529	fragment of putative variable tail fiber protein (partial);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585397008530	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
585397008531	baseplate assembly protein; Provisional; Region: J; PHA02568
585397008532	baseplate wedge subunit; Provisional; Region: W; PHA02516
585397008533	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
585397008534	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
585397008535	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
585397008536	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
585397008537	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
585397008538	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
585397008539	catalytic residues [active]
585397008540	P2-like prophage tail protein X [General function prediction only]; Region: COG5004
585397008541	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
585397008542	terminase endonuclease subunit; Provisional; Region: M; PHA02537
585397008543	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
585397008544	capsid protein; Provisional; Region: N; PHA02538
585397008545	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
585397008546	terminase ATPase subunit; Provisional; Region: P; PHA02535
585397008547	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
585397008548	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
585397008549	portal vertex protein; Provisional; Region: Q; PHA02536
585397008550	Phage portal protein; Region: Phage_portal; pfam04860
585397008551	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
585397008552	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397008553	non-specific DNA binding site [nucleotide binding]; other site
585397008554	salt bridge; other site
585397008555	sequence-specific DNA binding site [nucleotide binding]; other site
585397008556	TIGR04255 family protein; Region: sporadTIGR04255
585397008557	DinI-like family; Region: DinI; pfam06183
585397008558	fragment of conserved hypothetical protein (partial);Evidence 7 : Gene remnant
585397008559	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
585397008560	DNA adenine methylase (dam); Region: dam; TIGR00571
585397008561	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397008562	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397008563	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397008564	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397008565	Domain of Unknown Function with PDB structure (DUF3850); Region: DUF3850; pfam12961
585397008566	DksA-like zinc finger domain containing protein; Region: PHA00080
585397008567	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
585397008568	Phage regulatory protein CII (CP76); Region: Phage_CP76; pfam06892
585397008569	Predicted transcriptional regulator [Transcription]; Region: COG2932
585397008570	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
585397008571	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
585397008572	Catalytic site [active]
585397008573	integrase; Provisional; Region: int; PHA02601
585397008574	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
585397008575	active site
585397008576	DNA binding site [nucleotide binding]
585397008577	Int/Topo IB signature motif; other site
585397008578	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
585397008579	substrate binding pocket [chemical binding]; other site
585397008580	active site
585397008581	iron coordination sites [ion binding]; other site
585397008582	Predicted dehydrogenase [General function prediction only]; Region: COG0579
585397008583	hydroxyglutarate oxidase; Provisional; Region: PRK11728
585397008584	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
585397008585	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
585397008586	tetramerization interface [polypeptide binding]; other site
585397008587	NAD(P) binding site [chemical binding]; other site
585397008588	catalytic residues [active]
585397008589	4-aminobutyrate aminotransferase; Validated; Region: PRK08088
585397008590	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
585397008591	inhibitor-cofactor binding pocket; inhibition site
585397008592	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397008593	catalytic residue [active]
585397008594	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
585397008595	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
585397008596	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585397008597	DNA-binding site [nucleotide binding]; DNA binding site
585397008598	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
585397008599	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
585397008600	bacterial OsmY and nodulation domain; Region: BON; smart00749
585397008601	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
585397008602	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
585397008603	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
585397008604	dimerization interface [polypeptide binding]; other site
585397008605	putative DNA binding site [nucleotide binding]; other site
585397008606	Transcriptional regulators [Transcription]; Region: MarR; COG1846
585397008607	putative Zn2+ binding site [ion binding]; other site
585397008608	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YgaP, and similar uncharacterized putative rhodanese-related sulfurtransferases; Region: RHOD_YgaP; cd01527
585397008609	active site residue [active]
585397008610	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
585397008611	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
585397008612	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
585397008613	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
585397008614	hypothetical protein; Provisional; Region: PRK10556
585397008615	hypothetical protein; Provisional; Region: PRK10132
585397008616	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
585397008617	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585397008618	DNA-binding site [nucleotide binding]; DNA binding site
585397008619	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585397008620	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397008621	homodimer interface [polypeptide binding]; other site
585397008622	catalytic residue [active]
585397008623	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
585397008624	Uncharacterized conserved protein [Function unknown]; Region: COG2128
585397008625	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
585397008626	catalytic residues [active]
585397008627	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
585397008628	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
585397008629	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
585397008630	Class I ribonucleotide reductase; Region: RNR_I; cd01679
585397008631	active site
585397008632	dimer interface [polypeptide binding]; other site
585397008633	catalytic residues [active]
585397008634	effector binding site; other site
585397008635	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
585397008636	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
585397008637	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
585397008638	dimer interface [polypeptide binding]; other site
585397008639	putative radical transfer pathway; other site
585397008640	diiron center [ion binding]; other site
585397008641	tyrosyl radical; other site
585397008642	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
585397008643	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
585397008644	Walker A/P-loop; other site
585397008645	ATP binding site [chemical binding]; other site
585397008646	Q-loop/lid; other site
585397008647	ABC transporter signature motif; other site
585397008648	Walker B; other site
585397008649	D-loop; other site
585397008650	H-loop/switch region; other site
585397008651	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
585397008652	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
585397008653	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397008654	dimer interface [polypeptide binding]; other site
585397008655	conserved gate region; other site
585397008656	putative PBP binding loops; other site
585397008657	ABC-ATPase subunit interface; other site
585397008658	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
585397008659	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
585397008660	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
585397008661	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397008662	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
585397008663	putative L-valine exporter; Provisional; Region: PRK10408
585397008664	transcriptional repressor MprA; Provisional; Region: PRK10870
585397008665	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
585397008666	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
585397008667	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585397008668	HlyD family secretion protein; Region: HlyD_3; pfam13437
585397008669	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
585397008670	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397008671	putative substrate translocation pore; other site
585397008672	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397008673	S-ribosylhomocysteinase; Provisional; Region: PRK02260
585397008674	glutamate--cysteine ligase; Provisional; Region: PRK02107
585397008675	Predicted membrane protein [Function unknown]; Region: COG1238
585397008676	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
585397008677	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397008678	motif II; other site
585397008679	carbon storage regulator; Provisional; Region: PRK01712
585397008680	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
585397008681	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
585397008682	motif 1; other site
585397008683	active site
585397008684	motif 2; other site
585397008685	motif 3; other site
585397008686	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
585397008687	DHHA1 domain; Region: DHHA1; pfam02272
585397008688	recombination regulator RecX; Reviewed; Region: recX; PRK00117
585397008689	recombinase A; Provisional; Region: recA; PRK09354
585397008690	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
585397008691	hexamer interface [polypeptide binding]; other site
585397008692	Walker A motif; other site
585397008693	ATP binding site [chemical binding]; other site
585397008694	Walker B motif; other site
585397008695	hypothetical protein; Validated; Region: PRK03661
585397008696	Transglycosylase SLT domain; Region: SLT_2; pfam13406
585397008697	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
585397008698	N-acetyl-D-glucosamine binding site [chemical binding]; other site
585397008699	PTS system, glucitol/sorbitol-specific, IIC component; Region: EII-GUT; TIGR00821
585397008700	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
585397008701	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
585397008702	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
585397008703	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
585397008704	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
585397008705	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
585397008706	putative NAD(P) binding site [chemical binding]; other site
585397008707	active site
585397008708	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
585397008709	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
585397008710	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
585397008711	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585397008712	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
585397008713	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
585397008714	putative active site [active]
585397008715	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
585397008716	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
585397008717	GAF domain; Region: GAF; pfam01590
585397008718	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397008719	Walker A motif; other site
585397008720	ATP binding site [chemical binding]; other site
585397008721	Walker B motif; other site
585397008722	arginine finger; other site
585397008723	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
585397008724	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
585397008725	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
585397008726	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
585397008727	iron binding site [ion binding]; other site
585397008728	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
585397008729	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585397008730	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
585397008731	Acylphosphatase; Region: Acylphosphatase; pfam00708
585397008732	HypF finger; Region: zf-HYPF; pfam07503
585397008733	HypF finger; Region: zf-HYPF; pfam07503
585397008734	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
585397008735	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
585397008736	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
585397008737	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397008738	non-specific DNA binding site [nucleotide binding]; other site
585397008739	salt bridge; other site
585397008740	sequence-specific DNA binding site [nucleotide binding]; other site
585397008741	Uncharacterized protein conserved in bacteria (DUF2136); Region: DUF2136; cl01912
585397008742	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
585397008743	nickel binding site [ion binding]; other site
585397008744	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
585397008745	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
585397008746	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
585397008747	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
585397008748	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
585397008749	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
585397008750	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
585397008751	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
585397008752	NADH dehydrogenase; Region: NADHdh; cl00469
585397008753	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
585397008754	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
585397008755	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
585397008756	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
585397008757	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
585397008758	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
585397008759	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
585397008760	hydrogenase assembly chaperone; Provisional; Region: PRK10409
585397008761	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
585397008762	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
585397008763	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
585397008764	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
585397008765	dimerization interface [polypeptide binding]; other site
585397008766	ATP binding site [chemical binding]; other site
585397008767	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
585397008768	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
585397008769	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
585397008770	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397008771	Walker A motif; other site
585397008772	ATP binding site [chemical binding]; other site
585397008773	Walker B motif; other site
585397008774	arginine finger; other site
585397008775	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
585397008776	molybdenum-pterin binding domain; Region: Mop; TIGR00638
585397008777	Molybdopterin-binding protein [Coenzyme metabolism]; Region: MopI; COG3585
585397008778	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
585397008779	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
585397008780	MutS domain I; Region: MutS_I; pfam01624
585397008781	MutS domain II; Region: MutS_II; pfam05188
585397008782	MutS domain III; Region: MutS_III; pfam05192
585397008783	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
585397008784	Walker A/P-loop; other site
585397008785	ATP binding site [chemical binding]; other site
585397008786	Q-loop/lid; other site
585397008787	ABC transporter signature motif; other site
585397008788	Walker B; other site
585397008789	D-loop; other site
585397008790	H-loop/switch region; other site
585397008791	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
585397008792	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
585397008793	active site
585397008794	metal binding site [ion binding]; metal-binding site
585397008795	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
585397008796	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
585397008797	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585397008798	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
585397008799	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
585397008800	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
585397008801	putative aldolase; Validated; Region: PRK08130
585397008802	active site
585397008803	intersubunit interface [polypeptide binding]; other site
585397008804	Zn2+ binding site [ion binding]; other site
585397008805	hypothetical protein; Provisional; Region: PRK09989
585397008806	putative transporter; Provisional; Region: PRK09821
585397008807	GntP family permease; Region: GntP_permease; pfam02447
585397008808	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
585397008809	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
585397008810	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
585397008811	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
585397008812	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
585397008813	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
585397008814	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
585397008815	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
585397008816	DNA binding residues [nucleotide binding]
585397008817	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
585397008818	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
585397008819	Peptidase family M23; Region: Peptidase_M23; pfam01551
585397008820	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
585397008821	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397008822	S-adenosylmethionine binding site [chemical binding]; other site
585397008823	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
585397008824	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
585397008825	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
585397008826	Permutation of conserved domain; other site
585397008827	active site
585397008828	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
585397008829	homotrimer interaction site [polypeptide binding]; other site
585397008830	zinc binding site [ion binding]; other site
585397008831	CDP-binding sites; other site
585397008832	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
585397008833	substrate binding site; other site
585397008834	dimer interface; other site
585397008835	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
585397008836	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
585397008837	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
585397008838	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
585397008839	ligand-binding site [chemical binding]; other site
585397008840	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
585397008841	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
585397008842	CysD dimerization site [polypeptide binding]; other site
585397008843	G1 box; other site
585397008844	putative GEF interaction site [polypeptide binding]; other site
585397008845	GTP/Mg2+ binding site [chemical binding]; other site
585397008846	Switch I region; other site
585397008847	G2 box; other site
585397008848	G3 box; other site
585397008849	Switch II region; other site
585397008850	G4 box; other site
585397008851	G5 box; other site
585397008852	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
585397008853	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
585397008854	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
585397008855	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
585397008856	Active Sites [active]
585397008857	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
585397008858	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
585397008859	metal binding site [ion binding]; metal-binding site
585397008860	Hok/gef family; Region: HOK_GEF; pfam01848
585397008861	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
585397008862	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
585397008863	Active Sites [active]
585397008864	sulfite reductase subunit beta; Provisional; Region: PRK13504
585397008865	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
585397008866	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
585397008867	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
585397008868	Flavodoxin; Region: Flavodoxin_1; pfam00258
585397008869	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
585397008870	FAD binding pocket [chemical binding]; other site
585397008871	FAD binding motif [chemical binding]; other site
585397008872	catalytic residues [active]
585397008873	NAD binding pocket [chemical binding]; other site
585397008874	phosphate binding motif [ion binding]; other site
585397008875	beta-alpha-beta structure motif; other site
585397008876	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
585397008877	active site
585397008878	putative oxidoreductase FixC; Provisional; Region: PRK10157
585397008879	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
585397008880	Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]; Region: GlpP; COG1954
585397008881	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
585397008882	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
585397008883	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
585397008884	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
585397008885	Ligand binding site [chemical binding]; other site
585397008886	Electron transfer flavoprotein domain; Region: ETF; pfam01012
585397008887	benzoate transport; Region: 2A0115; TIGR00895
585397008888	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397008889	putative substrate translocation pore; other site
585397008890	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
585397008891	FAD binding domain; Region: FAD_binding_4; pfam01565
585397008892	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK06935
585397008893	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
585397008894	NADP binding site [chemical binding]; other site
585397008895	homodimer interface [polypeptide binding]; other site
585397008896	active site
585397008897	Major Facilitator Superfamily; Region: MFS_1; pfam07690
585397008898	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397008899	putative substrate translocation pore; other site
585397008900	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
585397008901	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
585397008902	nucleotide binding site [chemical binding]; other site
585397008903	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
585397008904	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
585397008905	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
585397008906	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
585397008907	Repair protein; Region: Repair_PSII; pfam04536
585397008908	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
585397008909	Repair protein; Region: Repair_PSII; pfam04536
585397008910	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
585397008911	Repair protein; Region: Repair_PSII; pfam04536
585397008912	enolase; Provisional; Region: eno; PRK00077
585397008913	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
585397008914	dimer interface [polypeptide binding]; other site
585397008915	metal binding site [ion binding]; metal-binding site
585397008916	substrate binding pocket [chemical binding]; other site
585397008917	CTP synthetase; Validated; Region: pyrG; PRK05380
585397008918	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
585397008919	Catalytic site [active]
585397008920	active site
585397008921	UTP binding site [chemical binding]; other site
585397008922	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
585397008923	active site
585397008924	putative oxyanion hole; other site
585397008925	catalytic triad [active]
585397008926	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
585397008927	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
585397008928	homodimer interface [polypeptide binding]; other site
585397008929	metal binding site [ion binding]; metal-binding site
585397008930	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
585397008931	homodimer interface [polypeptide binding]; other site
585397008932	active site
585397008933	putative chemical substrate binding site [chemical binding]; other site
585397008934	metal binding site [ion binding]; metal-binding site
585397008935	toxin MazF; Provisional; Region: PRK09907
585397008936	antitoxin MazE; Provisional; Region: PRK09798
585397008937	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
585397008938	HD domain; Region: HD_4; pfam13328
585397008939	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
585397008940	synthetase active site [active]
585397008941	NTP binding site [chemical binding]; other site
585397008942	metal binding site [ion binding]; metal-binding site
585397008943	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
585397008944	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
585397008945	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
585397008946	TRAM domain; Region: TRAM; pfam01938
585397008947	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397008948	S-adenosylmethionine binding site [chemical binding]; other site
585397008949	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
585397008950	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
585397008951	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585397008952	dimerization interface [polypeptide binding]; other site
585397008953	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585397008954	dimer interface [polypeptide binding]; other site
585397008955	phosphorylation site [posttranslational modification]
585397008956	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397008957	ATP binding site [chemical binding]; other site
585397008958	Mg2+ binding site [ion binding]; other site
585397008959	G-X-G motif; other site
585397008960	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
585397008961	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397008962	active site
585397008963	phosphorylation site [posttranslational modification]
585397008964	intermolecular recognition site; other site
585397008965	dimerization interface [polypeptide binding]; other site
585397008966	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
585397008967	putative binding surface; other site
585397008968	active site
585397008969	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
585397008970	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
585397008971	active site
585397008972	tetramer interface [polypeptide binding]; other site
585397008973	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
585397008974	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
585397008975	active site
585397008976	tetramer interface [polypeptide binding]; other site
585397008977	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397008978	D-galactonate transporter; Region: 2A0114; TIGR00893
585397008979	putative substrate translocation pore; other site
585397008980	flavodoxin; Provisional; Region: PRK08105
585397008981	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
585397008982	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
585397008983	probable active site [active]
585397008984	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
585397008985	SecY interacting protein Syd; Provisional; Region: PRK04968
585397008986	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
585397008987	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
585397008988	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
585397008989	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
585397008990	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
585397008991	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
585397008992	serine transporter; Region: stp; TIGR00814
585397008993	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
585397008994	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
585397008995	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
585397008996	flap endonuclease-like protein; Provisional; Region: PRK09482
585397008997	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
585397008998	active site
585397008999	metal binding site 1 [ion binding]; metal-binding site
585397009000	putative 5' ssDNA interaction site; other site
585397009001	metal binding site 3; metal-binding site
585397009002	metal binding site 2 [ion binding]; metal-binding site
585397009003	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
585397009004	putative DNA binding site [nucleotide binding]; other site
585397009005	putative metal binding site [ion binding]; other site
585397009006	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
585397009007	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
585397009008	dimer interface [polypeptide binding]; other site
585397009009	active site
585397009010	metal binding site [ion binding]; metal-binding site
585397009011	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
585397009012	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
585397009013	intersubunit interface [polypeptide binding]; other site
585397009014	active site
585397009015	Zn2+ binding site [ion binding]; other site
585397009016	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
585397009017	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397009018	putative substrate translocation pore; other site
585397009019	L-fucose isomerase; Provisional; Region: fucI; PRK10991
585397009020	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
585397009021	hexamer (dimer of trimers) interface [polypeptide binding]; other site
585397009022	trimer interface [polypeptide binding]; other site
585397009023	substrate binding site [chemical binding]; other site
585397009024	Mn binding site [ion binding]; other site
585397009025	L-fuculokinase; Provisional; Region: PRK10331
585397009026	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
585397009027	nucleotide binding site [chemical binding]; other site
585397009028	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
585397009029	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
585397009030	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
585397009031	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585397009032	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
585397009033	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
585397009034	hypothetical protein; Provisional; Region: PRK10873
585397009035	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
585397009036	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397009037	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
585397009038	dimerization interface [polypeptide binding]; other site
585397009039	substrate binding pocket [chemical binding]; other site
585397009040	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
585397009041	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
585397009042	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
585397009043	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
585397009044	catalytic residue [active]
585397009045	CsdA-binding activator; Provisional; Region: PRK15019
585397009046	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
585397009047	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
585397009048	putative ATP binding site [chemical binding]; other site
585397009049	putative substrate interface [chemical binding]; other site
585397009050	murein transglycosylase A; Provisional; Region: mltA; PRK11162
585397009051	MltA specific insert domain; Region: MltA; pfam03562
585397009052	3D domain; Region: 3D; pfam06725
585397009053	Putative D-3-Phosphoglycerate Dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_like_2; cd12172
585397009054	putative ligand binding site [chemical binding]; other site
585397009055	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
585397009056	putative NAD binding site [chemical binding]; other site
585397009057	catalytic site [active]
585397009058	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
585397009059	putative active site [active]
585397009060	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
585397009061	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585397009062	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397009063	homodimer interface [polypeptide binding]; other site
585397009064	catalytic residue [active]
585397009065	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
585397009066	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
585397009067	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
585397009068	active site turn [active]
585397009069	phosphorylation site [posttranslational modification]
585397009070	CAT RNA binding domain; Region: CAT_RBD; pfam03123
585397009071	PRD domain; Region: PRD; pfam00874
585397009072	PRD domain; Region: PRD; pfam00874
585397009073	AMIN domain; Region: AMIN; pfam11741
585397009074	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
585397009075	active site
585397009076	metal binding site [ion binding]; metal-binding site
585397009077	N-acetylglutamate synthase; Validated; Region: PRK05279
585397009078	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
585397009079	putative feedback inhibition sensing region; other site
585397009080	putative nucleotide binding site [chemical binding]; other site
585397009081	putative substrate binding site [chemical binding]; other site
585397009082	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585397009083	Coenzyme A binding pocket [chemical binding]; other site
585397009084	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
585397009085	AAA domain; Region: AAA_30; pfam13604
585397009086	Family description; Region: UvrD_C_2; pfam13538
585397009087	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
585397009088	protease3; Provisional; Region: PRK15101
585397009089	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
585397009090	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
585397009091	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
585397009092	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
585397009093	exodeoxyribonuclease V, gamma subunit; Region: recC; TIGR01450
585397009094	hypothetical protein; Provisional; Region: PRK10332
585397009095	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
585397009096	hypothetical protein; Provisional; Region: PRK11521
585397009097	hypothetical protein; Provisional; Region: PRK10557
585397009098	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
585397009099	hypothetical protein; Provisional; Region: PRK10506
585397009100	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
585397009101	thymidylate synthase; Reviewed; Region: thyA; PRK01827
585397009102	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
585397009103	dimerization interface [polypeptide binding]; other site
585397009104	active site
585397009105	prolipoprotein diacylglyceryl transferase; Region: lgt; TIGR00544
585397009106	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
585397009107	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
585397009108	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
585397009109	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
585397009110	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
585397009111	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
585397009112	putative active site [active]
585397009113	Ap4A binding site [chemical binding]; other site
585397009114	nudix motif; other site
585397009115	putative metal binding site [ion binding]; other site
585397009116	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
585397009117	putative DNA-binding cleft [nucleotide binding]; other site
585397009118	putative DNA clevage site; other site
585397009119	molecular lever; other site
585397009120	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
585397009121	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
585397009122	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
585397009123	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
585397009124	active site
585397009125	catalytic tetrad [active]
585397009126	lysophospholipid transporter LplT; Provisional; Region: PRK11195
585397009127	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397009128	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
585397009129	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
585397009130	putative acyl-acceptor binding pocket; other site
585397009131	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
585397009132	acyl-activating enzyme (AAE) consensus motif; other site
585397009133	putative AMP binding site [chemical binding]; other site
585397009134	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
585397009135	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585397009136	DNA binding site [nucleotide binding]
585397009137	domain linker motif; other site
585397009138	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
585397009139	dimerization interface (closed form) [polypeptide binding]; other site
585397009140	ligand binding site [chemical binding]; other site
585397009141	diaminopimelate decarboxylase; Provisional; Region: PRK11165
585397009142	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
585397009143	active site
585397009144	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
585397009145	substrate binding site [chemical binding]; other site
585397009146	catalytic residues [active]
585397009147	dimer interface [polypeptide binding]; other site
585397009148	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
585397009149	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397009150	The C-terminal substrate binding domain of LysR, transcriptional regulator for lysine biosynthesis, contains the type 2 periplasmic binding fold; Region: PBP2_LysR; cd08456
585397009151	putative dimerization interface [polypeptide binding]; other site
585397009152	putative racemase; Provisional; Region: PRK10200
585397009153	aspartate racemase; Region: asp_race; TIGR00035
585397009154	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
585397009155	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397009156	putative substrate translocation pore; other site
585397009157	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397009158	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
585397009159	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
585397009160	NADP binding site [chemical binding]; other site
585397009161	homodimer interface [polypeptide binding]; other site
585397009162	active site
585397009163	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
585397009164	putative acyltransferase; Provisional; Region: PRK05790
585397009165	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
585397009166	dimer interface [polypeptide binding]; other site
585397009167	active site
585397009168	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
585397009169	serine transporter; Region: stp; TIGR00814
585397009170	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
585397009171	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
585397009172	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
585397009173	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
585397009174	putative sialic acid transporter; Provisional; Region: PRK12307
585397009175	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397009176	putative substrate translocation pore; other site
585397009177	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
585397009178	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
585397009179	ssDNA binding site [nucleotide binding]; other site
585397009180	dimer interface [polypeptide binding]; other site
585397009181	tetramer (dimer of dimers) interface [polypeptide binding]; other site
585397009182	D5 N terminal like; Region: D5_N; smart00885
585397009183	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
585397009184	Poxvirus D5 protein-like; Region: Pox_D5; pfam03288
585397009185	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
585397009186	Ash protein family; Region: Phage_ASH; pfam10554
585397009187	Uncharacterized phage-encoded protein [Function unknown]; Region: COG3646
585397009188	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
585397009189	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; cl10713
585397009190	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
585397009191	integrase; Provisional; Region: PRK09692
585397009192	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
585397009193	active site
585397009194	Int/Topo IB signature motif; other site
585397009195	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
585397009196	Peptidase family M23; Region: Peptidase_M23; pfam01551
585397009197	xanthine dehydrogenase subunit XdhA; Provisional; Region: PRK09970
585397009198	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
585397009199	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
585397009200	xanthine dehydrogenase subunit XdhB; Provisional; Region: PRK09971
585397009201	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
585397009202	xanthine dehydrogenase subunit XdhC; Provisional; Region: PRK09908
585397009203	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
585397009204	catalytic loop [active]
585397009205	iron binding site [ion binding]; other site
585397009206	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
585397009207	GAF domain; Region: GAF; cl17456
585397009208	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
585397009209	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585397009210	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397009211	Walker A motif; other site
585397009212	ATP binding site [chemical binding]; other site
585397009213	Walker B motif; other site
585397009214	arginine finger; other site
585397009215	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
585397009216	aspartate/ornithine carbamoyltransferase family protein; Validated; Region: PRK07200
585397009217	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
585397009218	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
585397009219	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
585397009220	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
585397009221	catalytic residue [active]
585397009222	peptidase; Reviewed; Region: PRK13004
585397009223	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649
585397009224	putative metal binding site [ion binding]; other site
585397009225	putative dimer interface [polypeptide binding]; other site
585397009226	phenylhydantoinase; Validated; Region: PRK08323
585397009227	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
585397009228	tetramer interface [polypeptide binding]; other site
585397009229	active site
585397009230	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
585397009231	carbamate kinase; Reviewed; Region: PRK12686
585397009232	putative substrate binding site [chemical binding]; other site
585397009233	homodimer interface [polypeptide binding]; other site
585397009234	nucleotide binding site [chemical binding]; other site
585397009235	nucleotide binding site [chemical binding]; other site
585397009236	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
585397009237	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
585397009238	XdhC Rossmann domain; Region: XdhC_C; pfam13478
585397009239	selenium-dependent molybdenum hydroxylase system protein, YqeB family; Region: matur_yqeB; TIGR03309
585397009240	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
585397009241	probable selenium-dependent hydroxylase accessory protein YqeC; Region: TIGR03172
585397009242	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
585397009243	Ligand binding site; other site
585397009244	metal-binding site
585397009245	putative selenate reductase subunit YgfK; Provisional; Region: PRK09853
585397009246	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
585397009247	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
585397009248	putative selenium metabolism protein SsnA; Region: Se_ssnA; TIGR03314
585397009249	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
585397009250	active site
585397009251	putative substrate binding pocket [chemical binding]; other site
585397009252	probable selenate reductase, FAD-binding subunit; Region: Se_sel_red_FAD; TIGR03312
585397009253	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
585397009254	putative hypoxanthine oxidase; Provisional; Region: PRK09800
585397009255	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
585397009256	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
585397009257	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
585397009258	uracil-xanthine permease; Region: ncs2; TIGR00801
585397009259	guanine deaminase; Provisional; Region: PRK09228
585397009260	Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303
585397009261	active site
585397009262	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
585397009263	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
585397009264	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12809
585397009265	4Fe-4S binding domain; Region: Fer4; pfam00037
585397009266	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
585397009267	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585397009268	xanthine permease; Region: pbuX; TIGR03173
585397009269	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
585397009270	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
585397009271	active site
585397009272	metal binding site [ion binding]; metal-binding site
585397009273	nudix motif; other site
585397009274	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
585397009275	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
585397009276	dimer interface [polypeptide binding]; other site
585397009277	putative anticodon binding site; other site
585397009278	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
585397009279	motif 1; other site
585397009280	active site
585397009281	motif 2; other site
585397009282	motif 3; other site
585397009283	peptide chain release factor 2; Validated; Region: prfB; PRK00578
585397009284	This domain is found in peptide chain release factors; Region: PCRF; smart00937
585397009285	RF-1 domain; Region: RF-1; pfam00472
585397009286	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
585397009287	DHH family; Region: DHH; pfam01368
585397009288	DHHA1 domain; Region: DHHA1; pfam02272
585397009289	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
585397009290	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
585397009291	dimerization domain [polypeptide binding]; other site
585397009292	dimer interface [polypeptide binding]; other site
585397009293	catalytic residues [active]
585397009294	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
585397009295	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
585397009296	active site
585397009297	Int/Topo IB signature motif; other site
585397009298	flavodoxin FldB; Provisional; Region: PRK12359
585397009299	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
585397009300	hypothetical protein; Provisional; Region: PRK10878
585397009301	putative global regulator; Reviewed; Region: PRK09559
585397009302	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
585397009303	hemolysin; Provisional; Region: PRK15087
585397009304	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
585397009305	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
585397009306	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
585397009307	beta-galactosidase; Region: BGL; TIGR03356
585397009308	glycine dehydrogenase; Provisional; Region: PRK05367
585397009309	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
585397009310	tetramer interface [polypeptide binding]; other site
585397009311	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397009312	catalytic residue [active]
585397009313	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
585397009314	tetramer interface [polypeptide binding]; other site
585397009315	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397009316	catalytic residue [active]
585397009317	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
585397009318	lipoyl attachment site [posttranslational modification]; other site
585397009319	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
585397009320	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
585397009321	oxidoreductase; Provisional; Region: PRK08013
585397009322	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
585397009323	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
585397009324	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
585397009325	proline aminopeptidase P II; Provisional; Region: PRK10879
585397009326	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
585397009327	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
585397009328	active site
585397009329	hypothetical protein; Reviewed; Region: PRK01736
585397009330	Z-ring-associated protein; Provisional; Region: PRK10972
585397009331	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
585397009332	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
585397009333	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
585397009334	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
585397009335	ligand binding site [chemical binding]; other site
585397009336	NAD binding site [chemical binding]; other site
585397009337	tetramer interface [polypeptide binding]; other site
585397009338	catalytic site [active]
585397009339	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
585397009340	L-serine binding site [chemical binding]; other site
585397009341	ACT domain interface; other site
585397009342	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
585397009343	tetramer (dimer of dimers) interface [polypeptide binding]; other site
585397009344	active site
585397009345	dimer interface [polypeptide binding]; other site
585397009346	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
585397009347	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
585397009348	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397009349	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
585397009350	putative dimerization interface [polypeptide binding]; other site
585397009351	fragment of methylmalonyl-CoA mutase (partial);Evidence 7 : Gene remnant; Product type e : enzyme
585397009352	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397009353	Transcriptional regulator [Transcription]; Region: LysR; COG0583
585397009354	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
585397009355	dimerization interface [polypeptide binding]; other site
585397009356	Uncharacterized conserved protein [Function unknown]; Region: COG2968
585397009357	oxidative stress defense protein; Provisional; Region: PRK11087
585397009358	arginine exporter protein; Provisional; Region: PRK09304
585397009359	mechanosensitive channel MscS; Provisional; Region: PRK10334
585397009360	Mechanosensitive ion channel; Region: MS_channel; pfam00924
585397009361	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
585397009362	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
585397009363	active site
585397009364	intersubunit interface [polypeptide binding]; other site
585397009365	zinc binding site [ion binding]; other site
585397009366	Na+ binding site [ion binding]; other site
585397009367	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
585397009368	Phosphoglycerate kinase; Region: PGK; pfam00162
585397009369	substrate binding site [chemical binding]; other site
585397009370	hinge regions; other site
585397009371	ADP binding site [chemical binding]; other site
585397009372	catalytic site [active]
585397009373	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
585397009374	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
585397009375	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
585397009376	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
585397009377	trimer interface [polypeptide binding]; other site
585397009378	putative Zn binding site [ion binding]; other site
585397009379	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
585397009380	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
585397009381	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
585397009382	Walker A/P-loop; other site
585397009383	ATP binding site [chemical binding]; other site
585397009384	Q-loop/lid; other site
585397009385	ABC transporter signature motif; other site
585397009386	Walker B; other site
585397009387	D-loop; other site
585397009388	H-loop/switch region; other site
585397009389	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
585397009390	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
585397009391	Walker A/P-loop; other site
585397009392	ATP binding site [chemical binding]; other site
585397009393	Q-loop/lid; other site
585397009394	ABC transporter signature motif; other site
585397009395	Walker B; other site
585397009396	D-loop; other site
585397009397	H-loop/switch region; other site
585397009398	nucleoside triphosphate hydrolase domain-containing protein; Reviewed; Region: PRK09270
585397009399	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
585397009400	active site
585397009401	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
585397009402	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10022
585397009403	fragment of putative hexoseP phosphatase (part 2);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397009404	fragment of putative hexoseP phosphatase (part 1);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397009405	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
585397009406	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
585397009407	putative NAD(P) binding site [chemical binding]; other site
585397009408	catalytic Zn binding site [ion binding]; other site
585397009409	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
585397009410	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
585397009411	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
585397009412	active site
585397009413	P-loop; other site
585397009414	phosphorylation site [posttranslational modification]
585397009415	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
585397009416	active site
585397009417	phosphorylation site [posttranslational modification]
585397009418	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
585397009419	SPFH domain / Band 7 family; Region: Band_7; pfam01145
585397009420	transketolase; Reviewed; Region: PRK12753
585397009421	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
585397009422	TPP-binding site [chemical binding]; other site
585397009423	dimer interface [polypeptide binding]; other site
585397009424	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
585397009425	PYR/PP interface [polypeptide binding]; other site
585397009426	dimer interface [polypeptide binding]; other site
585397009427	TPP binding site [chemical binding]; other site
585397009428	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
585397009429	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
585397009430	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
585397009431	agmatinase; Region: agmatinase; TIGR01230
585397009432	oligomer interface [polypeptide binding]; other site
585397009433	putative active site [active]
585397009434	Mn binding site [ion binding]; other site
585397009435	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
585397009436	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
585397009437	dimer interface [polypeptide binding]; other site
585397009438	active site
585397009439	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
585397009440	catalytic residues [active]
585397009441	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
585397009442	Virulence promoting factor; Region: YqgB; pfam11036
585397009443	Protein of unknown function (DUF2684); Region: DUF2684; pfam10885
585397009444	S-adenosylmethionine synthetase; Validated; Region: PRK05250
585397009445	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
585397009446	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
585397009447	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
585397009448	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
585397009449	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397009450	putative substrate translocation pore; other site
585397009451	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397009452	hypothetical protein; Provisional; Region: PRK04860
585397009453	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
585397009454	DNA-specific endonuclease I; Provisional; Region: PRK15137
585397009455	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
585397009456	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
585397009457	RNA methyltransferase, RsmE family; Region: TIGR00046
585397009458	glutathione synthetase; Provisional; Region: PRK05246
585397009459	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
585397009460	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
585397009461	hypothetical protein; Validated; Region: PRK00228
585397009462	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
585397009463	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
585397009464	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
585397009465	Walker A motif; other site
585397009466	ATP binding site [chemical binding]; other site
585397009467	Walker B motif; other site
585397009468	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
585397009469	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
585397009470	catalytic residue [active]
585397009471	YGGT family; Region: YGGT; pfam02325
585397009472	YGGT family; Region: YGGT; pfam02325
585397009473	hypothetical protein; Validated; Region: PRK05090
585397009474	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
585397009475	active site
585397009476	dimerization interface [polypeptide binding]; other site
585397009477	HemN family oxidoreductase; Provisional; Region: PRK05660
585397009478	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585397009479	FeS/SAM binding site; other site
585397009480	HemN C-terminal domain; Region: HemN_C; pfam06969
585397009481	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
585397009482	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
585397009483	homodimer interface [polypeptide binding]; other site
585397009484	active site
585397009485	hypothetical protein; Provisional; Region: PRK10626
585397009486	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
585397009487	hypothetical protein; Provisional; Region: PRK11702
585397009488	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
585397009489	adenine DNA glycosylase; Provisional; Region: PRK10880
585397009490	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
585397009491	minor groove reading motif; other site
585397009492	helix-hairpin-helix signature motif; other site
585397009493	substrate binding pocket [chemical binding]; other site
585397009494	active site
585397009495	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
585397009496	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
585397009497	DNA binding and oxoG recognition site [nucleotide binding]
585397009498	oxidative damage protection protein; Provisional; Region: PRK05408
585397009499	murein transglycosylase C; Provisional; Region: mltC; PRK11671
585397009500	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
585397009501	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
585397009502	N-acetyl-D-glucosamine binding site [chemical binding]; other site
585397009503	catalytic residue [active]
585397009504	nucleoside transporter; Region: 2A0110; TIGR00889
585397009505	ornithine decarboxylase; Provisional; Region: PRK13578
585397009506	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
585397009507	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
585397009508	homodimer interface [polypeptide binding]; other site
585397009509	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397009510	catalytic residue [active]
585397009511	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
585397009512	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
585397009513	integrase; Provisional; Region: PRK09692
585397009514	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
585397009515	active site
585397009516	Int/Topo IB signature motif; other site
585397009517	transposase ORF 2, IS1 (part2);Evidence 2b : Function of strongly homologous gene; PubMedId : 1849492; Product type e : enzyme
585397009518	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397009519	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397009520	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397009521	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397009522	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
585397009523	arginine decarboxylase; Provisional; Region: PRK15029
585397009524	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
585397009525	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
585397009526	homodimer interface [polypeptide binding]; other site
585397009527	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397009528	catalytic residue [active]
585397009529	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
585397009530	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
585397009531	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397009532	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397009533	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397009534	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397009535	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
585397009536	fragment of conserved hypothetical protein (partial);Evidence 7 : Gene remnant
585397009537	ImpA domain protein; Region: DUF3702; pfam12486
585397009538	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
585397009539	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
585397009540	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
585397009541	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
585397009542	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
585397009543	putative active site [active]
585397009544	metal binding site [ion binding]; metal-binding site
585397009545	propanediol utilization phosphotransacylase; Provisional; Region: PRK15070
585397009546	Propanediol utilisation protein PduL; Region: PduL; pfam06130
585397009547	Propanediol utilisation protein PduL; Region: PduL; pfam06130
585397009548	ethanolamine utilization protein EutJ family protein; Region: EutJ; TIGR02529
585397009549	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
585397009550	nucleotide binding site [chemical binding]; other site
585397009551	Flavoprotein; Region: Flavoprotein; cl08021
585397009552	ethanolamine utilization protein; Region: eut_hyp; TIGR02536
585397009553	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
585397009554	Hexamer/Pentamer interface [polypeptide binding]; other site
585397009555	central pore; other site
585397009556	Domain of unknown function (DUF336); Region: DUF336; pfam03928
585397009557	propionate/acetate kinase; Provisional; Region: PRK12379
585397009558	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
585397009559	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
585397009560	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
585397009561	Hexamer interface [polypeptide binding]; other site
585397009562	Putative hexagonal pore residue; other site
585397009563	propanediol utilization protein PduB; Provisional; Region: PRK15415
585397009564	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduB_repeat1; cd07047
585397009565	putative hexamer interface [polypeptide binding]; other site
585397009566	putative hexagonal pore; other site
585397009567	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduB_repeat2; cd07048
585397009568	putative hexamer interface [polypeptide binding]; other site
585397009569	putative hexagonal pore; other site
585397009570	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
585397009571	putative catalytic cysteine [active]
585397009572	Bacterial Micro-Compartment (BMC)-like domain 2; Region: BMC_like_2; cd07055
585397009573	putative hexamer interface [polypeptide binding]; other site
585397009574	putative hexagonal pore; other site
585397009575	intracellular protease, PfpI family; Region: PfpI; TIGR01382
585397009576	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_1; cd03169
585397009577	conserved cys residue [active]
585397009578	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
585397009579	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
585397009580	dimer interface [polypeptide binding]; other site
585397009581	active site
585397009582	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
585397009583	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
585397009584	4Fe-4S binding domain; Region: Fer4; cl02805
585397009585	4Fe-4S binding domain; Region: Fer4_6; pfam12837
585397009586	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585397009587	FeS/SAM binding site; other site
585397009588	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
585397009589	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
585397009590	putative NTP binding site [chemical binding]; other site
585397009591	RT_like: Reverse transcriptase (RT, RNA-dependent DNA polymerase)_like family. An RT gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. RTs occur in a variety of mobile elements, including retrotransposons; Region: RT_like; cl02808
585397009592	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
585397009593	active site
585397009594	nucleic acid binding site [nucleotide binding]; other site
585397009595	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
585397009596	Sensory domain found in PocR; Region: PocR; pfam10114
585397009597	Predicted sensor domain [Signal transduction mechanisms / Transcription]; Region: PocR; COG4936
585397009598	Histidine kinase; Region: His_kinase; pfam06580
585397009599	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397009600	ATP binding site [chemical binding]; other site
585397009601	Mg2+ binding site [ion binding]; other site
585397009602	G-X-G motif; other site
585397009603	Response regulator receiver domain; Region: Response_reg; pfam00072
585397009604	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397009605	active site
585397009606	phosphorylation site [posttranslational modification]
585397009607	intermolecular recognition site; other site
585397009608	dimerization interface [polypeptide binding]; other site
585397009609	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397009610	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
585397009611	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397009612	S-adenosylmethionine synthetase; Validated; Region: PRK05250
585397009613	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
585397009614	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
585397009615	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
585397009616	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
585397009617	Hexamer interface [polypeptide binding]; other site
585397009618	Hexagonal pore residue; other site
585397009619	putative transcriptional activator RamA (partial);Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator
585397009620	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
585397009621	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585397009622	Protein export membrane protein; Region: SecD_SecF; cl14618
585397009623	fragment of IS2 insertion element repressor InsA; KpLE2 phage-like element (partial);Evidence 7 : Gene remnant; Product type r : regulator
585397009624	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
585397009625	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
585397009626	Predicted GTPase [General function prediction only]; Region: COG3596
585397009627	YfjP GTPase; Region: YfjP; cd11383
585397009628	G1 box; other site
585397009629	GTP/Mg2+ binding site [chemical binding]; other site
585397009630	Switch I region; other site
585397009631	G2 box; other site
585397009632	Switch II region; other site
585397009633	G3 box; other site
585397009634	G4 box; other site
585397009635	G5 box; other site
585397009636	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
585397009637	Domain of unknown function (DUF932); Region: DUF932; pfam06067
585397009638	Antirestriction protein; Region: Antirestrict; pfam03230
585397009639	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
585397009640	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
585397009641	MPN+ (JAMM) motif; other site
585397009642	Zinc-binding site [ion binding]; other site
585397009643	Protein of unknown function (DUF987); Region: DUF987; pfam06174
585397009644	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
585397009645	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
585397009646	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
585397009647	fragment of conserved hypothetical protein (partial);Evidence 7 : Gene remnant
585397009648	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
585397009649	active site
585397009650	catalytic residues [active]
585397009651	DNA binding site [nucleotide binding]
585397009652	Int/Topo IB signature motif; other site
585397009653	integrating conjugative element relaxase, PFL_4751 family; Region: ICE_TraI_Pfluor; TIGR03760
585397009654	Protein of unknown function (DUF1528); Region: DUF1528; pfam07515
585397009655	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
585397009656	Family description; Region: UvrD_C_2; pfam13538
585397009657	hypothetical protein; Provisional; Region: PRK09750
585397009658	putative PilL protein (fragment);Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12011003; Product type h : extrachromosomal origin
585397009659	PilM; Region: PilM; pfam07419
585397009660	type IVB pilus formation outer membrane protein, R64 PilN family; Region: pilus_B_mal_scr; TIGR02520
585397009661	Secretin N-terminal domain; Region: Secretin_N_2; pfam07655
585397009662	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
585397009663	Pilin accessory protein (PilO); Region: PAP_PilO; pfam06864
585397009664	type IV pilus biogenesis protein PilP; Region: pilP_fam; TIGR03021
585397009665	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
585397009666	Walker A motif; other site
585397009667	ATP binding site [chemical binding]; other site
585397009668	Walker B motif; other site
585397009669	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
585397009670	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
585397009671	PilS N terminal; Region: PilS; pfam08805
585397009672	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
585397009673	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
585397009674	N-acetyl-D-glucosamine binding site [chemical binding]; other site
585397009675	catalytic residue [active]
585397009676	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
585397009677	Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917
585397009678	Phage Tail Collar Domain; Region: Collar; pfam07484
585397009679	Rci recombinase, C-terminal catalytic domain.  Rci enzymes are found in IncI1 incompatibility group plasmids such as R64.  These recombinases belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain...; Region: INT_Rci; cd00796
585397009680	catalytic residues [active]
585397009681	Int/Topo IB signature motif; other site
585397009682	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
585397009683	fragment of Serine protease precursor (Secreted autotransporter toxin) (part 1);Evidence 7 : Gene remnant; Product type e : enzyme
585397009684	fragment of Serine protease precursor (Secreted autotransporter toxin) (part 2);Evidence 7 : Gene remnant; Product type e : enzyme
585397009685	Protein of unknown function (DUF1281); Region: DUF1281; pfam06924
585397009686	Protein of unknown function (DUF1281); Region: DUF1281; pfam06924
585397009687	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
585397009688	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
585397009689	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397009690	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397009691	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397009692	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397009693	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
585397009694	Protein of unknown function (DUF3268); Region: DUF3268; pfam11672
585397009695	Integrase; Region: Integrase_1; pfam12835
585397009696	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
585397009697	Integrase; Region: Integrase_1; pfam12835
585397009698	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
585397009699	conjugal transfer surface exclusion protein TraT; Provisional; Region: PRK13731
585397009700	Enterobacterial TraT complement resistance protein; Region: TraT; pfam05818
585397009701	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
585397009702	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
585397009703	Methyltransferase domain; Region: Methyltransf_26; pfam13659
585397009704	Diacylglycerol kinase (Diglyceride kinase) (fragment);Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10220339, 6257698, 86278195, 88111690, 2984194, 6309817, 8071224; Product type e : enzyme
585397009705	Sulfatase; Region: Sulfatase; pfam00884
585397009706	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
585397009707	putative iron-regulated outer membrane virulence protein; Provisional; Region: PRK13484
585397009708	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585397009709	N-terminal plug; other site
585397009710	ligand-binding site [chemical binding]; other site
585397009711	TraG-like protein, N-terminal region; Region: TraG_N; pfam07916
585397009712	integrating conjugative element protein, PFL_4711 family; Region: conj_TIGR03755
585397009713	integrating conjugative element protein, PFL_4710 family; Region: conj_TIGR03756
585397009714	Protein of unknown function (DUF1525); Region: DUF1525; pfam07511
585397009715	bifunctional enterobactin receptor/adhesin protein; Provisional; Region: PRK13486
585397009716	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585397009717	N-terminal plug; other site
585397009718	ligand-binding site [chemical binding]; other site
585397009719	conjugative transfer ATPase, PFL_4706 family; Region: traC_PFL_4706; TIGR03744
585397009720	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
585397009721	conjugative transfer region lipoprotein, TIGR03751 family; Region: conj_TIGR03751
585397009722	integrating conjugative element protein, PFL_4705 family; Region: conj_TIGR03752
585397009723	Modifier of rudimentary (Mod(r)) protein; Region: Mod_r; pfam07200
585397009724	Protein of unknown function (DUF3438); Region: DUF3438; pfam11920
585397009725	integrating conjugative element protein, PFL_4703 family; Region: conj_TIGR03746
585397009726	Protein of unknown function (DUF3487); Region: DUF3487; pfam11990
585397009727	Protein of unknown function (DUF2976); Region: DUF2976; cl12739
585397009728	Protein of unknown function (DUF3262); Region: DUF3262; pfam11660
585397009729	integrative conjugative element protein, RAQPRD family; Region: ICE_RAQPRD; TIGR01690
585397009730	Plasmid protein of unknown function (Plasmid_RAQPRD); Region: Plasmid_RAQPRD; pfam09686
585397009731	integrating conjugative element membrane protein, PFL_4697 family; Region: conj_TIGR03747
585397009732	conjugative coupling factor TraD, SXT/TOL subfamily; Region: SXT_TraD; TIGR03743
585397009733	conjugative coupling factor TraD, TOL family; Region: conj_TOL_TraD; TIGR03754
585397009734	Restriction endonuclease; Region: Mrr_cat; pfam04471
585397009735	Protein of unknown function (DUF2859); Region: DUF2859; pfam11072
585397009736	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
585397009737	integrating conjugative element protein, PFL_4693 family; Region: conj_TIGR03759
585397009738	Type IV B pilus protein;Evidence 2b : Function of strongly homologous gene; Product type s : structure
585397009739	Protein of unknown function (DUF433); Region: DUF433; cl01030
585397009740	fragment of transposase ORF B, IS911 (part 2);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397009741	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
585397009742	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
585397009743	putative active site [active]
585397009744	putative NTP binding site [chemical binding]; other site
585397009745	putative nucleic acid binding site [nucleotide binding]; other site
585397009746	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
585397009747	fragment of transposase ORF B (fragment), IS911 (partial);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397009748	fragment of transposase ORF A, IS3 family (partial);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397009749	putative transposase; Provisional; Region: PRK09857
585397009750	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
585397009751	Protein of unknown function (DUF433); Region: DUF433; cl01030
585397009752	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
585397009753	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
585397009754	dimer interface [polypeptide binding]; other site
585397009755	ssDNA binding site [nucleotide binding]; other site
585397009756	tetramer (dimer of dimers) interface [polypeptide binding]; other site
585397009757	Protein of unknown function (DUF3577); Region: DUF3577; pfam12101
585397009758	KpsF/GutQ family protein; Region: kpsF; TIGR00393
585397009759	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
585397009760	putative active site [active]
585397009761	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
585397009762	polysaccharide export inner-membrane protein, BexC/CtrB/KpsE family; Region: BexC_CtrB_KpsE; TIGR01010
585397009763	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
585397009764	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
585397009765	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
585397009766	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
585397009767	Ligand binding site; other site
585397009768	oligomer interface; other site
585397009769	Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsC; COG3563
585397009770	Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsS; COG3562
585397009771	Capsule polysaccharide biosynthesis protein; Region: Capsule_synth; pfam05159
585397009772	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
585397009773	active site
585397009774	trimer interface [polypeptide binding]; other site
585397009775	substrate binding site [chemical binding]; other site
585397009776	CoA binding site [chemical binding]; other site
585397009777	Capsule polysaccharide biosynthesis protein; Region: Capsule_synth; pfam05159
585397009778	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG5610
585397009779	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
585397009780	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
585397009781	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
585397009782	Walker A/P-loop; other site
585397009783	ATP binding site [chemical binding]; other site
585397009784	Q-loop/lid; other site
585397009785	ABC transporter signature motif; other site
585397009786	Walker B; other site
585397009787	D-loop; other site
585397009788	H-loop/switch region; other site
585397009789	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
585397009790	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
585397009791	putative general secretion pathway protein YghD; Provisional; Region: PRK09731
585397009792	type II secretion system protein L; Region: typeII_sec_gspL; TIGR01709
585397009793	GspL-like protein; Provisional; Region: PRK09662
585397009794	Type II secretion system (T2SS), protein K; Region: T2SK; pfam03934
585397009795	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
585397009796	type II secretion system protein J; Region: gspJ; TIGR01711
585397009797	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
585397009798	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
585397009799	type II secretion system protein I; Region: gspI; TIGR01707
585397009800	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
585397009801	Prokaryotic N-terminal methylation motif; Region: N_methyl; pfam07963
585397009802	Type II transport protein GspH; Region: GspH; pfam12019
585397009803	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
585397009804	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
585397009805	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
585397009806	type II secretion system protein F; Region: GspF; TIGR02120
585397009807	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
585397009808	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
585397009809	type II secretion system protein E; Region: type_II_gspE; TIGR02533
585397009810	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
585397009811	Walker A motif; other site
585397009812	ATP binding site [chemical binding]; other site
585397009813	Walker B motif; other site
585397009814	type II secretion system protein D; Region: type_II_gspD; TIGR02517
585397009815	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
585397009816	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
585397009817	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
585397009818	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
585397009819	putative type II secretion protein GspC; Provisional; Region: PRK09681
585397009820	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
585397009821	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
585397009822	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
585397009823	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
585397009824	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
585397009825	Domain of unknown function (DUF4092); Region: DUF4092; pfam13322
585397009826	Peptidase M60-like family; Region: M60-like; pfam13402
585397009827	glycolate transporter; Provisional; Region: PRK09695
585397009828	L-lactate permease; Region: Lactate_perm; cl00701
585397009829	Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate...; Region: malate_synt_G; cd00728
585397009830	active site
585397009831	hypothetical protein; Provisional; Region: PRK09732
585397009832	fragment of glycolate oxidase iron-sulfur subunit (partial);Evidence 7 : Gene remnant; Product type c : carrier
585397009833	glycolate oxidase FAD binding subunit; Provisional; Region: glcE; PRK11282
585397009834	FAD binding domain; Region: FAD_binding_4; pfam01565
585397009835	glycolate oxidase subunit GlcD; Provisional; Region: PRK11230
585397009836	FAD binding domain; Region: FAD_binding_4; pfam01565
585397009837	DNA-binding transcriptional regulator GlcC; Provisional; Region: PRK09990
585397009838	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585397009839	DNA-binding site [nucleotide binding]; DNA binding site
585397009840	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
585397009841	fragment of Putative AMP-dependent synthetase (part 1);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397009842	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
585397009843	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
585397009844	NAD(P) binding site [chemical binding]; other site
585397009845	active site
585397009846	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
585397009847	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
585397009848	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
585397009849	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
585397009850	catalytic residue [active]
585397009851	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
585397009852	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
585397009853	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
585397009854	Predicted permeases [General function prediction only]; Region: COG0795
585397009855	Bacterial protein of unknown function (YtfJ_HI0045); Region: YtfJ_HI0045; pfam09695
585397009856	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
585397009857	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
585397009858	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
585397009859	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
585397009860	active site
585397009861	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
585397009862	TMP-binding site; other site
585397009863	ATP-binding site [chemical binding]; other site
585397009864	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
585397009865	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
585397009866	TMP-binding site; other site
585397009867	ATP-binding site [chemical binding]; other site
585397009868	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
585397009869	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
585397009870	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
585397009871	CHAP domain; Region: CHAP; pfam05257
585397009872	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
585397009873	putative S-transferase; Provisional; Region: PRK11752
585397009874	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
585397009875	C-terminal domain interface [polypeptide binding]; other site
585397009876	GSH binding site (G-site) [chemical binding]; other site
585397009877	dimer interface [polypeptide binding]; other site
585397009878	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
585397009879	dimer interface [polypeptide binding]; other site
585397009880	N-terminal domain interface [polypeptide binding]; other site
585397009881	active site
585397009882	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
585397009883	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
585397009884	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
585397009885	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
585397009886	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
585397009887	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
585397009888	putative substrate-binding site; other site
585397009889	nickel binding site [ion binding]; other site
585397009890	hydrogenase 2 large subunit; Provisional; Region: PRK10467
585397009891	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
585397009892	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
585397009893	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
585397009894	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
585397009895	4Fe-4S binding domain; Region: Fer4_6; pfam12837
585397009896	hydrogenase 2 small subunit; Provisional; Region: PRK10468
585397009897	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
585397009898	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
585397009899	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
585397009900	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
585397009901	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
585397009902	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
585397009903	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
585397009904	active site
585397009905	catalytic tetrad [active]
585397009906	hypothetical protein; Provisional; Region: PRK05208
585397009907	oxidoreductase; Provisional; Region: PRK07985
585397009908	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
585397009909	NAD binding site [chemical binding]; other site
585397009910	metal binding site [ion binding]; metal-binding site
585397009911	active site
585397009912	biopolymer transport protein ExbD; Provisional; Region: PRK11267
585397009913	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
585397009914	biopolymer transport protein ExbB; Provisional; Region: PRK10414
585397009915	cystathionine beta-lyase; Provisional; Region: PRK08114
585397009916	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
585397009917	homodimer interface [polypeptide binding]; other site
585397009918	substrate-cofactor binding pocket; other site
585397009919	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397009920	catalytic residue [active]
585397009921	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
585397009922	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
585397009923	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
585397009924	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
585397009925	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397009926	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397009927	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
585397009928	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
585397009929	dimer interface [polypeptide binding]; other site
585397009930	active site
585397009931	metal binding site [ion binding]; metal-binding site
585397009932	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
585397009933	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
585397009934	active site
585397009935	catalytic tetrad [active]
585397009936	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397009937	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397009938	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397009939	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397009940	putative outer membrane lipoprotein; Provisional; Region: PRK09973
585397009941	hypothetical protein; Provisional; Region: PRK01254
585397009942	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
585397009943	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
585397009944	Transcriptional regulators [Transcription]; Region: FadR; COG2186
585397009945	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585397009946	DNA-binding site [nucleotide binding]; DNA binding site
585397009947	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
585397009948	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
585397009949	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
585397009950	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
585397009951	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
585397009952	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
585397009953	putative NAD(P) binding site [chemical binding]; other site
585397009954	catalytic Zn binding site [ion binding]; other site
585397009955	structural Zn binding site [ion binding]; other site
585397009956	Malate/L-lactate dehydrogenases [Energy production and conversion]; Region: COG2055
585397009957	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
585397009958	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
585397009959	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
585397009960	DctM-like transporters; Region: DctM; pfam06808
585397009961	TRAP transporter, DctM subunit; Region: dctM; TIGR00786
585397009962	FtsI repressor; Provisional; Region: PRK10883
585397009963	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
585397009964	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
585397009965	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
585397009966	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
585397009967	putative acyl-acceptor binding pocket; other site
585397009968	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
585397009969	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
585397009970	CAP-like domain; other site
585397009971	active site
585397009972	primary dimer interface [polypeptide binding]; other site
585397009973	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
585397009974	putative ABC transporter periplasmic-binding protein; Provisional; Region: PRK09755
585397009975	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
585397009976	peptide binding site [polypeptide binding]; other site
585397009977	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
585397009978	TIGR00156 family protein; Region: TIGR00156
585397009979	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
585397009980	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397009981	active site
585397009982	phosphorylation site [posttranslational modification]
585397009983	intermolecular recognition site; other site
585397009984	dimerization interface [polypeptide binding]; other site
585397009985	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585397009986	DNA binding site [nucleotide binding]
585397009987	sensor protein QseC; Provisional; Region: PRK10337
585397009988	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585397009989	dimer interface [polypeptide binding]; other site
585397009990	phosphorylation site [posttranslational modification]
585397009991	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397009992	ATP binding site [chemical binding]; other site
585397009993	Mg2+ binding site [ion binding]; other site
585397009994	G-X-G motif; other site
585397009995	fragment of conserved hypothetical protein; putative inner membrane protein (partial);Evidence 7 : Gene remnant; Product type pm : putative membrane component
585397009996	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
585397009997	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
585397009998	Uncharacterized conserved protein [Function unknown]; Region: COG1359
585397009999	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
585397010000	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
585397010001	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cd04795
585397010002	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
585397010003	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
585397010004	siderophore binding site; other site
585397010005	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
585397010006	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
585397010007	ABC-ATPase subunit  interface; other site
585397010008	dimer interface [polypeptide binding]; other site
585397010009	putative PBP binding regions; other site
585397010010	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
585397010011	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
585397010012	dimer interface [polypeptide binding]; other site
585397010013	putative PBP binding regions; other site
585397010014	ABC-ATPase subunit  interface; other site
585397010015	fragment of ferric enterobactin transport ATP-binding protein (fepC-like) (part 2);Evidence 7 : Gene remnant; Product type t : transporter
585397010016	fragment of ferric enterobactin transport ATP-binding protein (fepC-like) (part 1);Evidence 7 : Gene remnant; Product type t : transporter
585397010017	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
585397010018	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585397010019	N-terminal plug; other site
585397010020	ligand-binding site [chemical binding]; other site
585397010021	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
585397010022	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397010023	ATP binding site [chemical binding]; other site
585397010024	Mg2+ binding site [ion binding]; other site
585397010025	G-X-G motif; other site
585397010026	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
585397010027	anchoring element; other site
585397010028	dimer interface [polypeptide binding]; other site
585397010029	ATP binding site [chemical binding]; other site
585397010030	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
585397010031	active site
585397010032	metal binding site [ion binding]; metal-binding site
585397010033	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
585397010034	esterase YqiA; Provisional; Region: PRK11071
585397010035	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
585397010036	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
585397010037	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
585397010038	active site
585397010039	metal binding site [ion binding]; metal-binding site
585397010040	hexamer interface [polypeptide binding]; other site
585397010041	putative dehydrogenase; Provisional; Region: PRK11039
585397010042	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
585397010043	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
585397010044	dimer interface [polypeptide binding]; other site
585397010045	ADP-ribose binding site [chemical binding]; other site
585397010046	active site
585397010047	nudix motif; other site
585397010048	metal binding site [ion binding]; metal-binding site
585397010049	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
585397010050	hypothetical protein; Provisional; Region: PRK11653
585397010051	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
585397010052	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
585397010053	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
585397010054	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
585397010055	catalytic residues [active]
585397010056	hinge region; other site
585397010057	alpha helical domain; other site
585397010058	putative disulfide oxidoreductase; Provisional; Region: PRK04307
585397010059	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
585397010060	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
585397010061	putative active site [active]
585397010062	metal binding site [ion binding]; metal-binding site
585397010063	zinc transporter ZupT; Provisional; Region: PRK04201
585397010064	ZIP Zinc transporter; Region: Zip; pfam02535
585397010065	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
585397010066	putative fimbrial protein; Provisional; Region: PRK09733
585397010067	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
585397010068	PapC N-terminal domain; Region: PapC_N; pfam13954
585397010069	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585397010070	PapC C-terminal domain; Region: PapC_C; pfam13953
585397010071	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
585397010072	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585397010073	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
585397010074	Fimbrial protein; Region: Fimbrial; pfam00419
585397010075	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
585397010076	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
585397010077	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
585397010078	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
585397010079	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
585397010080	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
585397010081	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
585397010082	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
585397010083	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
585397010084	putative ribose interaction site [chemical binding]; other site
585397010085	putative ADP binding site [chemical binding]; other site
585397010086	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
585397010087	active site
585397010088	nucleotide binding site [chemical binding]; other site
585397010089	HIGH motif; other site
585397010090	KMSKS motif; other site
585397010091	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
585397010092	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
585397010093	metal binding triad; other site
585397010094	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
585397010095	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
585397010096	metal binding triad; other site
585397010097	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
585397010098	Uncharacterized conserved protein [Function unknown]; Region: COG3025
585397010099	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
585397010100	putative active site [active]
585397010101	putative metal binding residues [ion binding]; other site
585397010102	signature motif; other site
585397010103	putative triphosphate binding site [ion binding]; other site
585397010104	CHAD domain; Region: CHAD; pfam05235
585397010105	SH3 domain-containing protein; Provisional; Region: PRK10884
585397010106	Bacterial SH3 domain homologues; Region: SH3b; smart00287
585397010107	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
585397010108	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
585397010109	active site
585397010110	NTP binding site [chemical binding]; other site
585397010111	metal binding triad [ion binding]; metal-binding site
585397010112	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
585397010113	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
585397010114	Zn2+ binding site [ion binding]; other site
585397010115	Mg2+ binding site [ion binding]; other site
585397010116	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
585397010117	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
585397010118	homooctamer interface [polypeptide binding]; other site
585397010119	active site
585397010120	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
585397010121	transcriptional activator TtdR; Provisional; Region: PRK09801
585397010122	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397010123	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
585397010124	putative effector binding pocket; other site
585397010125	putative dimerization interface [polypeptide binding]; other site
585397010126	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
585397010127	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
585397010128	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
585397010129	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
585397010130	transmembrane helices; other site
585397010131	UGMP family protein; Validated; Region: PRK09604
585397010132	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
585397010133	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
585397010134	DNA primase; Validated; Region: dnaG; PRK05667
585397010135	CHC2 zinc finger; Region: zf-CHC2; pfam01807
585397010136	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
585397010137	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
585397010138	active site
585397010139	metal binding site [ion binding]; metal-binding site
585397010140	interdomain interaction site; other site
585397010141	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
585397010142	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
585397010143	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
585397010144	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
585397010145	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
585397010146	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
585397010147	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
585397010148	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
585397010149	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
585397010150	DNA binding residues [nucleotide binding]
585397010151	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
585397010152	active site
585397010153	SUMO-1 interface [polypeptide binding]; other site
585397010154	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
585397010155	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
585397010156	FAD binding pocket [chemical binding]; other site
585397010157	FAD binding motif [chemical binding]; other site
585397010158	phosphate binding motif [ion binding]; other site
585397010159	NAD binding pocket [chemical binding]; other site
585397010160	Predicted transcriptional regulators [Transcription]; Region: COG1695
585397010161	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
585397010162	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585397010163	PAS fold; Region: PAS_3; pfam08447
585397010164	putative active site [active]
585397010165	heme pocket [chemical binding]; other site
585397010166	HAMP domain; Region: HAMP; pfam00672
585397010167	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
585397010168	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
585397010169	dimer interface [polypeptide binding]; other site
585397010170	putative CheW interface [polypeptide binding]; other site
585397010171	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
585397010172	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
585397010173	inhibitor-cofactor binding pocket; inhibition site
585397010174	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397010175	catalytic residue [active]
585397010176	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
585397010177	dimer interface [polypeptide binding]; other site
585397010178	putative tRNA-binding site [nucleotide binding]; other site
585397010179	DNA-binding transcriptional repressor EbgR; Provisional; Region: PRK10339
585397010180	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585397010181	DNA binding site [nucleotide binding]
585397010182	domain linker motif; other site
585397010183	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
585397010184	putative dimerization interface [polypeptide binding]; other site
585397010185	putative ligand binding site [chemical binding]; other site
585397010186	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
585397010187	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
585397010188	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
585397010189	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
585397010190	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
585397010191	cryptic beta-D-galactosidase subunit beta; Reviewed; Region: ebgC; PRK10202
585397010192	inner membrane transporter YjeM; Provisional; Region: PRK15238
585397010193	alpha-glucosidase; Provisional; Region: PRK10137
585397010194	Protein of unknown function, DUF608; Region: DUF608; pfam04685
585397010195	Trehalase; Region: Trehalase; cl17346
585397010196	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
585397010197	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
585397010198	active site
585397010199	FMN binding site [chemical binding]; other site
585397010200	2,4-decadienoyl-CoA binding site; other site
585397010201	catalytic residue [active]
585397010202	4Fe-4S cluster binding site [ion binding]; other site
585397010203	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
585397010204	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397010205	non-specific DNA binding site [nucleotide binding]; other site
585397010206	salt bridge; other site
585397010207	sequence-specific DNA binding site [nucleotide binding]; other site
585397010208	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
585397010209	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397010210	S-adenosylmethionine binding site [chemical binding]; other site
585397010211	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
585397010212	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
585397010213	putative active site [active]
585397010214	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
585397010215	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
585397010216	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
585397010217	serine/threonine transporter SstT; Provisional; Region: PRK13628
585397010218	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
585397010219	Bacterial inner membrane protein; Region: Imp-YgjV; pfam10688
585397010220	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
585397010221	galactarate dehydratase; Region: galactar-dH20; TIGR03248
585397010222	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
585397010223	Glucuronate isomerase; Region: UxaC; pfam02614
585397010224	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
585397010225	fragment of hexuronate transporter (part 1);Evidence 7 : Gene remnant; Product type t : transporter
585397010226	fragment of hexuronate transporter (part 2);Evidence 7 : Gene remnant; Product type t : transporter
585397010227	DNA-binding transcriptional repressor ExuR; Provisional; Region: PRK11523
585397010228	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585397010229	DNA-binding site [nucleotide binding]; DNA binding site
585397010230	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
585397010231	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
585397010232	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
585397010233	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
585397010234	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
585397010235	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
585397010236	Predicted membrane protein [Function unknown]; Region: COG5393
585397010237	YqjK-like protein; Region: YqjK; pfam13997
585397010238	Predicted membrane protein [Function unknown]; Region: COG2259
585397010239	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
585397010240	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
585397010241	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
585397010242	putative dimer interface [polypeptide binding]; other site
585397010243	N-terminal domain interface [polypeptide binding]; other site
585397010244	putative substrate binding pocket (H-site) [chemical binding]; other site
585397010245	Predicted membrane protein [Function unknown]; Region: COG3152
585397010246	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397010247	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
585397010248	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
585397010249	dimerization interface [polypeptide binding]; other site
585397010250	Pirin-related protein [General function prediction only]; Region: COG1741
585397010251	Pirin; Region: Pirin; pfam02678
585397010252	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
585397010253	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
585397010254	serine transporter; Region: stp; TIGR00814
585397010255	L-serine dehydratase TdcG; Provisional; Region: PRK15040
585397010256	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
585397010257	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
585397010258	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
585397010259	homotrimer interaction site [polypeptide binding]; other site
585397010260	putative active site [active]
585397010261	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
585397010262	Pyruvate formate lyase 1; Region: PFL1; cd01678
585397010263	coenzyme A binding site [chemical binding]; other site
585397010264	active site
585397010265	catalytic residues [active]
585397010266	glycine loop; other site
585397010267	propionate/acetate kinase; Provisional; Region: PRK12379
585397010268	Acetokinase family; Region: Acetate_kinase; cl17229
585397010269	threonine/serine transporter TdcC; Provisional; Region: PRK13629
585397010270	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
585397010271	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
585397010272	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
585397010273	tetramer interface [polypeptide binding]; other site
585397010274	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397010275	catalytic residue [active]
585397010276	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
585397010277	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397010278	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
585397010279	putative substrate binding pocket [chemical binding]; other site
585397010280	putative dimerization interface [polypeptide binding]; other site
585397010281	DNA-binding transcriptional activator TdcR; Provisional; Region: PRK11424
585397010282	glycerate kinase I; Provisional; Region: PRK10342
585397010283	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
585397010284	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
585397010285	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
585397010286	fragment of putative (D)-galactarate transporter (partial);Evidence 7 : Gene remnant; Product type pt : putative transporter
585397010287	galactarate dehydratase; Region: galactar-dH20; TIGR03248
585397010288	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
585397010289	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
585397010290	putative regulator PrlF; Provisional; Region: PRK09974
585397010291	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
585397010292	Toxin with endonuclease activity YhaV; Region: Toxin_YhaV; pfam11663
585397010293	DNA-binding transcriptional regulator AgaR; Provisional; Region: PRK09802
585397010294	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
585397010295	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585397010296	tagatose 6-phosphate aldolase subunit KbaZ; Provisional; Region: PRK15458
585397010297	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
585397010298	active site
585397010299	phosphorylation site [posttranslational modification]
585397010300	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
585397010301	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
585397010302	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
585397010303	active pocket/dimerization site; other site
585397010304	active site
585397010305	phosphorylation site [posttranslational modification]
585397010306	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
585397010307	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
585397010308	active site
585397010309	dimer interface [polypeptide binding]; other site
585397010310	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
585397010311	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
585397010312	dimer interface [polypeptide binding]; other site
585397010313	active site
585397010314	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
585397010315	putative active site [active]
585397010316	Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cd00453
585397010317	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
585397010318	active site
585397010319	intersubunit interface [polypeptide binding]; other site
585397010320	zinc binding site [ion binding]; other site
585397010321	Na+ binding site [ion binding]; other site
585397010322	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
585397010323	active site
585397010324	phosphorylation site [posttranslational modification]
585397010325	PTS system N-acetylgalactosamine-specific transporter subunit IIC; Provisional; Region: PRK09757
585397010326	PTS system N-acetylgalactosamine-specific transporter subunit IID; Provisional; Region: PRK09855
585397010327	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
585397010328	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
585397010329	active site
585397010330	trimer interface [polypeptide binding]; other site
585397010331	allosteric site; other site
585397010332	active site lid [active]
585397010333	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
585397010334	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
585397010335	putative SAM binding site [chemical binding]; other site
585397010336	putative homodimer interface [polypeptide binding]; other site
585397010337	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
585397010338	putative ligand binding site [chemical binding]; other site
585397010339	TIGR00252 family protein; Region: TIGR00252
585397010340	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
585397010341	dimer interface [polypeptide binding]; other site
585397010342	active site
585397010343	outer membrane lipoprotein; Provisional; Region: PRK11023
585397010344	BON domain; Region: BON; pfam04972
585397010345	BON domain; Region: BON; pfam04972
585397010346	Predicted permease; Region: DUF318; pfam03773
585397010347	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
585397010348	NADH(P)-binding; Region: NAD_binding_10; pfam13460
585397010349	NAD binding site [chemical binding]; other site
585397010350	active site
585397010351	intracellular protease, PfpI family; Region: PfpI; TIGR01382
585397010352	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
585397010353	proposed catalytic triad [active]
585397010354	conserved cys residue [active]
585397010355	hypothetical protein; Provisional; Region: PRK03467
585397010356	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
585397010357	GIY-YIG motif/motif A; other site
585397010358	putative active site [active]
585397010359	putative metal binding site [ion binding]; other site
585397010360	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
585397010361	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585397010362	Coenzyme A binding pocket [chemical binding]; other site
585397010363	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
585397010364	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
585397010365	Peptidase family U32; Region: Peptidase_U32; pfam01136
585397010366	putative protease; Provisional; Region: PRK15447
585397010367	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
585397010368	hypothetical protein; Provisional; Region: PRK10508
585397010369	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
585397010370	tryptophan permease; Provisional; Region: PRK10483
585397010371	aromatic amino acid transport protein; Region: araaP; TIGR00837
585397010372	ATP-dependent RNA helicase DeaD; Provisional; Region: PRK11634
585397010373	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
585397010374	ATP binding site [chemical binding]; other site
585397010375	Mg++ binding site [ion binding]; other site
585397010376	motif III; other site
585397010377	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585397010378	nucleotide binding region [chemical binding]; other site
585397010379	ATP-binding site [chemical binding]; other site
585397010380	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
585397010381	putative RNA binding site [nucleotide binding]; other site
585397010382	lipoprotein NlpI; Provisional; Region: PRK11189
585397010383	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585397010384	binding surface
585397010385	TPR motif; other site
585397010386	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
585397010387	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
585397010388	RNase E interface [polypeptide binding]; other site
585397010389	trimer interface [polypeptide binding]; other site
585397010390	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
585397010391	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
585397010392	RNase E interface [polypeptide binding]; other site
585397010393	trimer interface [polypeptide binding]; other site
585397010394	active site
585397010395	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
585397010396	putative nucleic acid binding region [nucleotide binding]; other site
585397010397	G-X-X-G motif; other site
585397010398	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
585397010399	RNA binding site [nucleotide binding]; other site
585397010400	domain interface; other site
585397010401	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
585397010402	16S/18S rRNA binding site [nucleotide binding]; other site
585397010403	S13e-L30e interaction site [polypeptide binding]; other site
585397010404	25S rRNA binding site [nucleotide binding]; other site
585397010405	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
585397010406	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
585397010407	RNA binding site [nucleotide binding]; other site
585397010408	active site
585397010409	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
585397010410	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
585397010411	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
585397010412	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
585397010413	translation initiation factor IF-2; Region: IF-2; TIGR00487
585397010414	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
585397010415	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
585397010416	G1 box; other site
585397010417	putative GEF interaction site [polypeptide binding]; other site
585397010418	GTP/Mg2+ binding site [chemical binding]; other site
585397010419	Switch I region; other site
585397010420	G2 box; other site
585397010421	G3 box; other site
585397010422	Switch II region; other site
585397010423	G4 box; other site
585397010424	G5 box; other site
585397010425	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
585397010426	Translation-initiation factor 2; Region: IF-2; pfam11987
585397010427	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
585397010428	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
585397010429	NusA N-terminal domain; Region: NusA_N; pfam08529
585397010430	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
585397010431	RNA binding site [nucleotide binding]; other site
585397010432	homodimer interface [polypeptide binding]; other site
585397010433	NusA-like KH domain; Region: KH_5; pfam13184
585397010434	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
585397010435	G-X-X-G motif; other site
585397010436	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
585397010437	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
585397010438	ribosome maturation protein RimP; Reviewed; Region: PRK00092
585397010439	Sm and related proteins; Region: Sm_like; cl00259
585397010440	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
585397010441	putative oligomer interface [polypeptide binding]; other site
585397010442	putative RNA binding site [nucleotide binding]; other site
585397010443	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
585397010444	ANP binding site [chemical binding]; other site
585397010445	Substrate Binding Site II [chemical binding]; other site
585397010446	Substrate Binding Site I [chemical binding]; other site
585397010447	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
585397010448	Sulfatase; Region: Sulfatase; pfam00884
585397010449	Preprotein translocase SecG subunit; Region: SecG; pfam03840
585397010450	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
585397010451	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
585397010452	active site
585397010453	substrate binding site [chemical binding]; other site
585397010454	metal binding site [ion binding]; metal-binding site
585397010455	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
585397010456	dihydropteroate synthase; Region: DHPS; TIGR01496
585397010457	substrate binding pocket [chemical binding]; other site
585397010458	dimer interface [polypeptide binding]; other site
585397010459	inhibitor binding site; inhibition site
585397010460	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
585397010461	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397010462	Walker A motif; other site
585397010463	ATP binding site [chemical binding]; other site
585397010464	Walker B motif; other site
585397010465	arginine finger; other site
585397010466	Peptidase family M41; Region: Peptidase_M41; pfam01434
585397010467	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
585397010468	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397010469	S-adenosylmethionine binding site [chemical binding]; other site
585397010470	RNA-binding protein YhbY; Provisional; Region: PRK10343
585397010471	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
585397010472	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
585397010473	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
585397010474	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
585397010475	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
585397010476	GTPase CgtA; Reviewed; Region: obgE; PRK12298
585397010477	GTP1/OBG; Region: GTP1_OBG; pfam01018
585397010478	Obg GTPase; Region: Obg; cd01898
585397010479	G1 box; other site
585397010480	GTP/Mg2+ binding site [chemical binding]; other site
585397010481	Switch I region; other site
585397010482	G2 box; other site
585397010483	G3 box; other site
585397010484	Switch II region; other site
585397010485	G4 box; other site
585397010486	G5 box; other site
585397010487	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
585397010488	EamA-like transporter family; Region: EamA; pfam00892
585397010489	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
585397010490	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
585397010491	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
585397010492	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
585397010493	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
585397010494	substrate binding pocket [chemical binding]; other site
585397010495	chain length determination region; other site
585397010496	substrate-Mg2+ binding site; other site
585397010497	catalytic residues [active]
585397010498	aspartate-rich region 1; other site
585397010499	active site lid residues [active]
585397010500	aspartate-rich region 2; other site
585397010501	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
585397010502	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
585397010503	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
585397010504	hinge; other site
585397010505	active site
585397010506	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
585397010507	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
585397010508	anti sigma factor interaction site; other site
585397010509	regulatory phosphorylation site [posttranslational modification]; other site
585397010510	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
585397010511	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
585397010512	mce related protein; Region: MCE; pfam02470
585397010513	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
585397010514	conserved hypothetical integral membrane protein; Region: TIGR00056
585397010515	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
585397010516	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
585397010517	Walker A/P-loop; other site
585397010518	ATP binding site [chemical binding]; other site
585397010519	Q-loop/lid; other site
585397010520	ABC transporter signature motif; other site
585397010521	Walker B; other site
585397010522	D-loop; other site
585397010523	H-loop/switch region; other site
585397010524	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
585397010525	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
585397010526	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
585397010527	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
585397010528	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
585397010529	putative active site [active]
585397010530	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
585397010531	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
585397010532	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
585397010533	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
585397010534	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
585397010535	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
585397010536	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
585397010537	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
585397010538	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
585397010539	Walker A/P-loop; other site
585397010540	ATP binding site [chemical binding]; other site
585397010541	Q-loop/lid; other site
585397010542	ABC transporter signature motif; other site
585397010543	Walker B; other site
585397010544	D-loop; other site
585397010545	H-loop/switch region; other site
585397010546	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
585397010547	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
585397010548	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
585397010549	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
585397010550	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
585397010551	30S subunit binding site; other site
585397010552	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
585397010553	active site
585397010554	phosphorylation site [posttranslational modification]
585397010555	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
585397010556	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
585397010557	dimerization domain swap beta strand [polypeptide binding]; other site
585397010558	regulatory protein interface [polypeptide binding]; other site
585397010559	active site
585397010560	regulatory phosphorylation site [posttranslational modification]; other site
585397010561	hypothetical protein; Provisional; Region: PRK10345
585397010562	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
585397010563	Transglycosylase; Region: Transgly; cl17702
585397010564	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
585397010565	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
585397010566	conserved cys residue [active]
585397010567	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
585397010568	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585397010569	putative active site [active]
585397010570	heme pocket [chemical binding]; other site
585397010571	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585397010572	dimer interface [polypeptide binding]; other site
585397010573	phosphorylation site [posttranslational modification]
585397010574	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397010575	ATP binding site [chemical binding]; other site
585397010576	Mg2+ binding site [ion binding]; other site
585397010577	G-X-G motif; other site
585397010578	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397010579	active site
585397010580	phosphorylation site [posttranslational modification]
585397010581	intermolecular recognition site; other site
585397010582	dimerization interface [polypeptide binding]; other site
585397010583	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
585397010584	putative binding surface; other site
585397010585	active site
585397010586	radical SAM protein, TIGR01212 family; Region: TIGR01212
585397010587	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585397010588	FeS/SAM binding site; other site
585397010589	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
585397010590	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
585397010591	active site
585397010592	dimer interface [polypeptide binding]; other site
585397010593	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
585397010594	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
585397010595	active site
585397010596	FMN binding site [chemical binding]; other site
585397010597	substrate binding site [chemical binding]; other site
585397010598	3Fe-4S cluster binding site [ion binding]; other site
585397010599	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
585397010600	domain interface; other site
585397010601	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
585397010602	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
585397010603	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585397010604	Domain of unknown function (DUF386); Region: DUF386; cl01047
585397010605	N-acetylmannosamine kinase; Provisional; Region: PRK05082
585397010606	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
585397010607	nucleotide binding site [chemical binding]; other site
585397010608	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
585397010609	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
585397010610	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
585397010611	putative active site cavity [active]
585397010612	putative sialic acid transporter; Provisional; Region: PRK03893
585397010613	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397010614	putative substrate translocation pore; other site
585397010615	N-acetylneuraminate lyase; Region: nanA; TIGR00683
585397010616	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
585397010617	inhibitor site; inhibition site
585397010618	active site
585397010619	dimer interface [polypeptide binding]; other site
585397010620	catalytic residue [active]
585397010621	transcriptional regulator NanR; Provisional; Region: PRK03837
585397010622	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585397010623	DNA-binding site [nucleotide binding]; DNA binding site
585397010624	FCD domain; Region: FCD; pfam07729
585397010625	Stringent starvation protein B [General function prediction only]; Region: SspB; COG2969
585397010626	stringent starvation protein A; Provisional; Region: sspA; PRK09481
585397010627	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
585397010628	C-terminal domain interface [polypeptide binding]; other site
585397010629	putative GSH binding site (G-site) [chemical binding]; other site
585397010630	dimer interface [polypeptide binding]; other site
585397010631	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
585397010632	dimer interface [polypeptide binding]; other site
585397010633	N-terminal domain interface [polypeptide binding]; other site
585397010634	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
585397010635	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
585397010636	23S rRNA interface [nucleotide binding]; other site
585397010637	L3 interface [polypeptide binding]; other site
585397010638	Predicted ATPase [General function prediction only]; Region: COG1485
585397010639	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
585397010640	hypothetical protein; Provisional; Region: PRK11677
585397010641	serine endoprotease; Provisional; Region: PRK10139
585397010642	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
585397010643	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
585397010644	protein binding site [polypeptide binding]; other site
585397010645	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
585397010646	serine endoprotease; Provisional; Region: PRK10898
585397010647	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
585397010648	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
585397010649	malate dehydrogenase; Provisional; Region: PRK05086
585397010650	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
585397010651	NAD binding site [chemical binding]; other site
585397010652	dimerization interface [polypeptide binding]; other site
585397010653	Substrate binding site [chemical binding]; other site
585397010654	arginine repressor; Provisional; Region: PRK05066
585397010655	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
585397010656	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
585397010657	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
585397010658	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
585397010659	RNAase interaction site [polypeptide binding]; other site
585397010660	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
585397010661	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
585397010662	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
585397010663	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585397010664	HlyD family secretion protein; Region: HlyD_3; pfam13437
585397010665	efflux system membrane protein; Provisional; Region: PRK11594
585397010666	transcriptional regulator; Provisional; Region: PRK10632
585397010667	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397010668	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
585397010669	putative effector binding pocket; other site
585397010670	dimerization interface [polypeptide binding]; other site
585397010671	protease TldD; Provisional; Region: tldD; PRK10735
585397010672	hypothetical protein; Provisional; Region: PRK10899
585397010673	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
585397010674	ribonuclease G; Provisional; Region: PRK11712
585397010675	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
585397010676	homodimer interface [polypeptide binding]; other site
585397010677	oligonucleotide binding site [chemical binding]; other site
585397010678	Maf-like protein; Region: Maf; pfam02545
585397010679	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
585397010680	active site
585397010681	dimer interface [polypeptide binding]; other site
585397010682	rod shape-determining protein MreD; Provisional; Region: PRK11060
585397010683	rod shape-determining protein MreC; Region: mreC; TIGR00219
585397010684	rod shape-determining protein MreC; Region: MreC; pfam04085
585397010685	rod shape-determining protein MreB; Provisional; Region: PRK13927
585397010686	MreB and similar proteins; Region: MreB_like; cd10225
585397010687	nucleotide binding site [chemical binding]; other site
585397010688	Mg binding site [ion binding]; other site
585397010689	putative protofilament interaction site [polypeptide binding]; other site
585397010690	RodZ interaction site [polypeptide binding]; other site
585397010691	regulatory protein CsrD; Provisional; Region: PRK11059
585397010692	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585397010693	metal binding site [ion binding]; metal-binding site
585397010694	active site
585397010695	I-site; other site
585397010696	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585397010697	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
585397010698	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
585397010699	NADP binding site [chemical binding]; other site
585397010700	dimer interface [polypeptide binding]; other site
585397010701	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
585397010702	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
585397010703	carboxyltransferase (CT) interaction site; other site
585397010704	biotinylation site [posttranslational modification]; other site
585397010705	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
585397010706	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
585397010707	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
585397010708	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
585397010709	Aldose 1-epimerase, similar to Escherichia coli c4013; Region: Aldose_epim_Ec_c4013; cd09023
585397010710	active site
585397010711	catalytic residues [active]
585397010712	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
585397010713	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
585397010714	substrate binding site [chemical binding]; other site
585397010715	ATP binding site [chemical binding]; other site
585397010716	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585397010717	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585397010718	TM-ABC transporter signature motif; other site
585397010719	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
585397010720	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
585397010721	Walker A/P-loop; other site
585397010722	ATP binding site [chemical binding]; other site
585397010723	Q-loop/lid; other site
585397010724	ABC transporter signature motif; other site
585397010725	Walker B; other site
585397010726	D-loop; other site
585397010727	H-loop/switch region; other site
585397010728	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
585397010729	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
585397010730	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_12; cd06322
585397010731	putative ligand binding site [chemical binding]; other site
585397010732	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
585397010733	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
585397010734	intersubunit interface [polypeptide binding]; other site
585397010735	active site
585397010736	zinc binding site [ion binding]; other site
585397010737	Na+ binding site [ion binding]; other site
585397010738	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
585397010739	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
585397010740	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585397010741	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
585397010742	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
585397010743	substrate binding site [chemical binding]; other site
585397010744	ATP binding site [chemical binding]; other site
585397010745	hypothetical protein; Provisional; Region: PRK10633
585397010746	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
585397010747	Na binding site [ion binding]; other site
585397010748	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
585397010749	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
585397010750	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
585397010751	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
585397010752	FMN binding site [chemical binding]; other site
585397010753	active site
585397010754	catalytic residues [active]
585397010755	substrate binding site [chemical binding]; other site
585397010756	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
585397010757	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
585397010758	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
585397010759	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397010760	DNA methylase; Region: N6_N4_Mtase; pfam01555
585397010761	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
585397010762	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
585397010763	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585397010764	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
585397010765	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
585397010766	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585397010767	HlyD family secretion protein; Region: HlyD_3; pfam13437
585397010768	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
585397010769	Protein export membrane protein; Region: SecD_SecF; cl14618
585397010770	Transposase IS200 like; Region: Y1_Tnp; pfam01797
585397010771	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
585397010772	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
585397010773	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585397010774	substrate binding pocket [chemical binding]; other site
585397010775	membrane-bound complex binding site; other site
585397010776	hinge residues; other site
585397010777	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: BatB; COG4597
585397010778	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397010779	conserved gate region; other site
585397010780	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397010781	dimer interface [polypeptide binding]; other site
585397010782	conserved gate region; other site
585397010783	putative PBP binding loops; other site
585397010784	ABC-ATPase subunit interface; other site
585397010785	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397010786	dimer interface [polypeptide binding]; other site
585397010787	conserved gate region; other site
585397010788	putative PBP binding loops; other site
585397010789	ABC-ATPase subunit interface; other site
585397010790	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
585397010791	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
585397010792	Walker A/P-loop; other site
585397010793	ATP binding site [chemical binding]; other site
585397010794	Q-loop/lid; other site
585397010795	ABC transporter signature motif; other site
585397010796	Walker B; other site
585397010797	D-loop; other site
585397010798	H-loop/switch region; other site
585397010799	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
585397010800	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
585397010801	trimer interface [polypeptide binding]; other site
585397010802	putative metal binding site [ion binding]; other site
585397010803	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
585397010804	shikimate 5-dehydrogenase; Region: aroE; TIGR00507
585397010805	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
585397010806	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
585397010807	shikimate binding site; other site
585397010808	NAD(P) binding site [chemical binding]; other site
585397010809	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
585397010810	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
585397010811	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
585397010812	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
585397010813	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
585397010814	hypothetical protein; Validated; Region: PRK03430
585397010815	hypothetical protein; Provisional; Region: PRK10736
585397010816	DNA protecting protein DprA; Region: dprA; TIGR00732
585397010817	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
585397010818	active site
585397010819	catalytic residues [active]
585397010820	metal binding site [ion binding]; metal-binding site
585397010821	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
585397010822	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
585397010823	putative active site [active]
585397010824	substrate binding site [chemical binding]; other site
585397010825	putative cosubstrate binding site; other site
585397010826	catalytic site [active]
585397010827	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
585397010828	substrate binding site [chemical binding]; other site
585397010829	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
585397010830	putative RNA binding site [nucleotide binding]; other site
585397010831	16S rRNA methyltransferase B; Provisional; Region: PRK10901
585397010832	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397010833	S-adenosylmethionine binding site [chemical binding]; other site
585397010834	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
585397010835	TrkA-N domain; Region: TrkA_N; pfam02254
585397010836	TrkA-C domain; Region: TrkA_C; pfam02080
585397010837	TrkA-N domain; Region: TrkA_N; pfam02254
585397010838	TrkA-C domain; Region: TrkA_C; pfam02080
585397010839	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
585397010840	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
585397010841	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
585397010842	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
585397010843	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
585397010844	DNA binding residues [nucleotide binding]
585397010845	dimer interface [polypeptide binding]; other site
585397010846	metal binding site [ion binding]; metal-binding site
585397010847	hypothetical protein; Provisional; Region: PRK10203
585397010848	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
585397010849	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
585397010850	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
585397010851	alphaNTD homodimer interface [polypeptide binding]; other site
585397010852	alphaNTD - beta interaction site [polypeptide binding]; other site
585397010853	alphaNTD - beta' interaction site [polypeptide binding]; other site
585397010854	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
585397010855	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
585397010856	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
585397010857	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
585397010858	RNA binding surface [nucleotide binding]; other site
585397010859	30S ribosomal protein S11; Validated; Region: PRK05309
585397010860	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
585397010861	30S ribosomal protein S13; Region: bact_S13; TIGR03631
585397010862	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
585397010863	SecY translocase; Region: SecY; pfam00344
585397010864	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
585397010865	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
585397010866	23S rRNA binding site [nucleotide binding]; other site
585397010867	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
585397010868	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
585397010869	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
585397010870	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
585397010871	23S rRNA interface [nucleotide binding]; other site
585397010872	5S rRNA interface [nucleotide binding]; other site
585397010873	L27 interface [polypeptide binding]; other site
585397010874	L5 interface [polypeptide binding]; other site
585397010875	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
585397010876	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
585397010877	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
585397010878	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
585397010879	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
585397010880	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
585397010881	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
585397010882	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
585397010883	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
585397010884	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
585397010885	RNA binding site [nucleotide binding]; other site
585397010886	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
585397010887	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
585397010888	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
585397010889	23S rRNA interface [nucleotide binding]; other site
585397010890	putative translocon interaction site; other site
585397010891	signal recognition particle (SRP54) interaction site; other site
585397010892	L23 interface [polypeptide binding]; other site
585397010893	trigger factor interaction site; other site
585397010894	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
585397010895	23S rRNA interface [nucleotide binding]; other site
585397010896	5S rRNA interface [nucleotide binding]; other site
585397010897	putative antibiotic binding site [chemical binding]; other site
585397010898	L25 interface [polypeptide binding]; other site
585397010899	L27 interface [polypeptide binding]; other site
585397010900	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
585397010901	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
585397010902	G-X-X-G motif; other site
585397010903	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
585397010904	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
585397010905	protein-rRNA interface [nucleotide binding]; other site
585397010906	putative translocon binding site; other site
585397010907	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
585397010908	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
585397010909	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
585397010910	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
585397010911	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
585397010912	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
585397010913	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
585397010914	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
585397010915	protein secretion protein GspB; Provisional; Region: PRK09697
585397010916	fragment of general secretory pathway component, cryptic (part 2);Evidence 7 : Gene remnant; Product type t : transporter
585397010917	fragment of general secretory pathway component, cryptic (part 1);Evidence 7 : Gene remnant; Product type t : transporter
585397010918	Type II secretory pathway, component PulC [Intracellular trafficking and secretion]; Region: PulC; COG3031
585397010919	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
585397010920	type II secretion system protein D; Region: type_II_gspD; TIGR02517
585397010921	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
585397010922	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
585397010923	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
585397010924	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
585397010925	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
585397010926	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
585397010927	Walker A motif; other site
585397010928	ATP binding site [chemical binding]; other site
585397010929	Walker B motif; other site
585397010930	type II secretion system protein F; Region: GspF; TIGR02120
585397010931	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
585397010932	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
585397010933	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
585397010934	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
585397010935	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
585397010936	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
585397010937	type II secretion system protein I; Region: gspI; TIGR01707
585397010938	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
585397010939	Type II secretory pathway, component PulJ [Intracellular trafficking and secretion]; Region: PulJ; COG4795
585397010940	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
585397010941	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
585397010942	Chitin/cellulose binding domains of chitinase and related enzymes; Region: ChtBD3; cl00046
585397010943	Chitin/cellulose binding domains of chitinase and related enzymes; Region: ChtBD3; cl00046
585397010944	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
585397010945	aromatic chitin/cellulose binding site residues [chemical binding]; other site
585397010946	PF-ChiA is an uncharacterized chitinase found in the hyperthermophilic archaeon Pyrococcus furiosus with a glycosyl hydrolase family 18 (GH18) catalytic domain as well as a cellulose-binding domain.  Members of this domain family are found not only in...; Region: GH18_PF-ChiA-like; cd06543
585397010947	active site
585397010948	elongation factor Tu; Reviewed; Region: PRK00049
585397010949	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
585397010950	G1 box; other site
585397010951	GEF interaction site [polypeptide binding]; other site
585397010952	GTP/Mg2+ binding site [chemical binding]; other site
585397010953	Switch I region; other site
585397010954	G2 box; other site
585397010955	G3 box; other site
585397010956	Switch II region; other site
585397010957	G4 box; other site
585397010958	G5 box; other site
585397010959	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
585397010960	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
585397010961	Antibiotic Binding Site [chemical binding]; other site
585397010962	elongation factor G; Reviewed; Region: PRK00007
585397010963	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
585397010964	G1 box; other site
585397010965	putative GEF interaction site [polypeptide binding]; other site
585397010966	GTP/Mg2+ binding site [chemical binding]; other site
585397010967	Switch I region; other site
585397010968	G2 box; other site
585397010969	G3 box; other site
585397010970	Switch II region; other site
585397010971	G4 box; other site
585397010972	G5 box; other site
585397010973	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
585397010974	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
585397010975	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
585397010976	30S ribosomal protein S7; Validated; Region: PRK05302
585397010977	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
585397010978	S17 interaction site [polypeptide binding]; other site
585397010979	S8 interaction site; other site
585397010980	16S rRNA interaction site [nucleotide binding]; other site
585397010981	streptomycin interaction site [chemical binding]; other site
585397010982	23S rRNA interaction site [nucleotide binding]; other site
585397010983	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
585397010984	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
585397010985	sulfur relay protein TusC; Validated; Region: PRK00211
585397010986	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
585397010987	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
585397010988	YheO-like PAS domain; Region: PAS_6; pfam08348
585397010989	HTH domain; Region: HTH_22; pfam13309
585397010990	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
585397010991	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
585397010992	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
585397010993	phi X174 lysis protein; Provisional; Region: PRK02793
585397010994	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
585397010995	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
585397010996	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
585397010997	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
585397010998	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
585397010999	TrkA-N domain; Region: TrkA_N; pfam02254
585397011000	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
585397011001	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
585397011002	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397011003	Walker A/P-loop; other site
585397011004	ATP binding site [chemical binding]; other site
585397011005	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
585397011006	ABC transporter signature motif; other site
585397011007	Walker B; other site
585397011008	D-loop; other site
585397011009	ABC transporter; Region: ABC_tran_2; pfam12848
585397011010	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
585397011011	putative hydrolase; Provisional; Region: PRK10985
585397011012	hypothetical protein; Provisional; Region: PRK04966
585397011013	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
585397011014	active site
585397011015	hypothetical protein; Provisional; Region: PRK10738
585397011016	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
585397011017	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
585397011018	ligand binding site [chemical binding]; other site
585397011019	flexible hinge region; other site
585397011020	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
585397011021	putative switch regulator; other site
585397011022	non-specific DNA interactions [nucleotide binding]; other site
585397011023	DNA binding site [nucleotide binding]
585397011024	sequence specific DNA binding site [nucleotide binding]; other site
585397011025	putative cAMP binding site [chemical binding]; other site
585397011026	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
585397011027	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
585397011028	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
585397011029	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
585397011030	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
585397011031	inhibitor-cofactor binding pocket; inhibition site
585397011032	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397011033	catalytic residue [active]
585397011034	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
585397011035	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
585397011036	glutamine binding [chemical binding]; other site
585397011037	catalytic triad [active]
585397011038	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
585397011039	cell filamentation protein Fic; Provisional; Region: PRK10347
585397011040	hypothetical protein; Provisional; Region: PRK10204
585397011041	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
585397011042	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
585397011043	substrate binding site [chemical binding]; other site
585397011044	putative transporter; Provisional; Region: PRK03699
585397011045	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397011046	putative substrate translocation pore; other site
585397011047	nitrite reductase subunit NirD; Provisional; Region: PRK14989
585397011048	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585397011049	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
585397011050	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
585397011051	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
585397011052	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
585397011053	nitrite transporter NirC; Provisional; Region: PRK11562
585397011054	siroheme synthase; Provisional; Region: cysG; PRK10637
585397011055	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
585397011056	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
585397011057	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
585397011058	active site
585397011059	SAM binding site [chemical binding]; other site
585397011060	homodimer interface [polypeptide binding]; other site
585397011061	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
585397011062	DNA topoisomerase III, bacteria and conjugative plasmid; Region: topB; TIGR01056
585397011063	Protein of unknown function; Region: YhfT; pfam10797
585397011064	Protein of unknown function DUF2620; Region: DUF2620; pfam10941
585397011065	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
585397011066	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
585397011067	active site
585397011068	substrate binding pocket [chemical binding]; other site
585397011069	homodimer interaction site [polypeptide binding]; other site
585397011070	putative mutase; Provisional; Region: PRK12383
585397011071	Phosphopentomutase [Carbohydrate transport and metabolism]; Region: DeoB; COG1015
585397011072	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme yhfX; Region: PLPDE_III_yhfX_like; cd06811
585397011073	dimer interface [polypeptide binding]; other site
585397011074	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
585397011075	active site
585397011076	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
585397011077	substrate binding site [chemical binding]; other site
585397011078	catalytic residue [active]
585397011079	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
585397011080	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
585397011081	active site
585397011082	HIGH motif; other site
585397011083	dimer interface [polypeptide binding]; other site
585397011084	KMSKS motif; other site
585397011085	phosphoglycolate phosphatase; Provisional; Region: PRK13222
585397011086	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397011087	motif II; other site
585397011088	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
585397011089	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
585397011090	substrate binding site [chemical binding]; other site
585397011091	hexamer interface [polypeptide binding]; other site
585397011092	metal binding site [ion binding]; metal-binding site
585397011093	DNA adenine methylase; Provisional; Region: PRK10904
585397011094	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DamX; COG3266
585397011095	cell division protein DamX; Validated; Region: PRK10905
585397011096	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
585397011097	active site
585397011098	dimer interface [polypeptide binding]; other site
585397011099	metal binding site [ion binding]; metal-binding site
585397011100	shikimate kinase; Reviewed; Region: aroK; PRK00131
585397011101	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
585397011102	ADP binding site [chemical binding]; other site
585397011103	magnesium binding site [ion binding]; other site
585397011104	putative shikimate binding site; other site
585397011105	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
585397011106	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
585397011107	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
585397011108	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
585397011109	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
585397011110	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
585397011111	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
585397011112	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
585397011113	Transglycosylase; Region: Transgly; pfam00912
585397011114	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
585397011115	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
585397011116	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
585397011117	ADP-ribose binding site [chemical binding]; other site
585397011118	dimer interface [polypeptide binding]; other site
585397011119	active site
585397011120	nudix motif; other site
585397011121	metal binding site [ion binding]; metal-binding site
585397011122	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
585397011123	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
585397011124	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397011125	motif II; other site
585397011126	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
585397011127	RNA binding surface [nucleotide binding]; other site
585397011128	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
585397011129	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
585397011130	dimerization interface [polypeptide binding]; other site
585397011131	domain crossover interface; other site
585397011132	redox-dependent activation switch; other site
585397011133	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
585397011134	Glycosyl hydrolase family 81; Region: Glyco_hydro_81; cl02310
585397011135	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
585397011136	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
585397011137	active site
585397011138	substrate-binding site [chemical binding]; other site
585397011139	metal-binding site [ion binding]
585397011140	ATP binding site [chemical binding]; other site
585397011141	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
585397011142	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585397011143	dimerization interface [polypeptide binding]; other site
585397011144	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585397011145	dimer interface [polypeptide binding]; other site
585397011146	phosphorylation site [posttranslational modification]
585397011147	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397011148	ATP binding site [chemical binding]; other site
585397011149	G-X-G motif; other site
585397011150	osmolarity response regulator; Provisional; Region: ompR; PRK09468
585397011151	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397011152	active site
585397011153	phosphorylation site [posttranslational modification]
585397011154	intermolecular recognition site; other site
585397011155	dimerization interface [polypeptide binding]; other site
585397011156	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585397011157	DNA binding site [nucleotide binding]
585397011158	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
585397011159	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
585397011160	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
585397011161	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
585397011162	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
585397011163	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
585397011164	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
585397011165	RNA binding site [nucleotide binding]; other site
585397011166	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
585397011167	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
585397011168	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
585397011169	G1 box; other site
585397011170	GTP/Mg2+ binding site [chemical binding]; other site
585397011171	Switch I region; other site
585397011172	G2 box; other site
585397011173	G3 box; other site
585397011174	Switch II region; other site
585397011175	G4 box; other site
585397011176	G5 box; other site
585397011177	Nucleoside recognition; Region: Gate; pfam07670
585397011178	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
585397011179	Nucleoside recognition; Region: Gate; pfam07670
585397011180	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
585397011181	fragment of putative transposase (partial);Evidence 7 : Gene remnant; Product type ph : phenotype
585397011182	carboxylesterase BioH; Provisional; Region: PRK10349
585397011183	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
585397011184	DNA utilization protein GntX; Provisional; Region: PRK11595
585397011185	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
585397011186	active site
585397011187	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
585397011188	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
585397011189	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
585397011190	high-affinity gluconate transporter; Provisional; Region: PRK14984
585397011191	gluconate transporter; Region: gntP; TIGR00791
585397011192	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
585397011193	4-alpha-glucanotransferase; Region: Glyco_hydro_77; cl00711
585397011194	maltodextrin phosphorylase; Provisional; Region: PRK14985
585397011195	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
585397011196	homodimer interface [polypeptide binding]; other site
585397011197	active site pocket [active]
585397011198	transcriptional regulator MalT; Provisional; Region: PRK04841
585397011199	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585397011200	DNA binding residues [nucleotide binding]
585397011201	RNA 3'-terminal-phosphate cyclase; Provisional; Region: PRK04204
585397011202	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288
585397011203	putative active site [active]
585397011204	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
585397011205	hypothetical protein; Reviewed; Region: PRK09588
585397011206	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
585397011207	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
585397011208	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397011209	Walker A motif; other site
585397011210	ATP binding site [chemical binding]; other site
585397011211	Walker B motif; other site
585397011212	arginine finger; other site
585397011213	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
585397011214	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
585397011215	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585397011216	intramembrane serine protease GlpG; Provisional; Region: PRK10907
585397011217	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
585397011218	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
585397011219	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
585397011220	active site residue [active]
585397011221	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
585397011222	hypothetical protein; Provisional; Region: PRK09781; cl08057
585397011223	Fimbrial protein; Region: Fimbrial; cl01416
585397011224	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397011225	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397011226	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397011227	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397011228	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
585397011229	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585397011230	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
585397011231	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
585397011232	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
585397011233	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397011234	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397011235	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397011236	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397011237	PapC N-terminal domain; Region: PapC_N; pfam13954
585397011238	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585397011239	fimbrial chaperone protein StiB; Provisional; Region: PRK15299
585397011240	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585397011241	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
585397011242	fragment of Auf fimbriae major fimbrial subunit AufA (partial);Evidence 7 : Gene remnant; Product type s : structure
585397011243	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397011244	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397011245	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397011246	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397011247	glycogen phosphorylase; Provisional; Region: PRK14986
585397011248	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
585397011249	homodimer interface [polypeptide binding]; other site
585397011250	active site pocket [active]
585397011251	glycogen synthase; Provisional; Region: glgA; PRK00654
585397011252	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
585397011253	ADP-binding pocket [chemical binding]; other site
585397011254	homodimer interface [polypeptide binding]; other site
585397011255	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
585397011256	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
585397011257	ligand binding site; other site
585397011258	oligomer interface; other site
585397011259	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
585397011260	sulfate 1 binding site; other site
585397011261	glycogen debranching enzyme; Provisional; Region: PRK03705
585397011262	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
585397011263	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
585397011264	active site
585397011265	catalytic site [active]
585397011266	glycogen branching enzyme; Provisional; Region: PRK05402
585397011267	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
585397011268	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
585397011269	active site
585397011270	catalytic site [active]
585397011271	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
585397011272	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
585397011273	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
585397011274	putative antibiotic transporter; Provisional; Region: PRK10739
585397011275	low affinity gluconate transporter; Provisional; Region: PRK10472
585397011276	gluconate transporter; Region: gntP; TIGR00791
585397011277	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
585397011278	ATP-binding site [chemical binding]; other site
585397011279	Gluconate-6-phosphate binding site [chemical binding]; other site
585397011280	Shikimate kinase; Region: SKI; pfam01202
585397011281	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
585397011282	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585397011283	DNA binding site [nucleotide binding]
585397011284	domain linker motif; other site
585397011285	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
585397011286	putative ligand binding site [chemical binding]; other site
585397011287	putative dimerization interface [polypeptide binding]; other site
585397011288	Pirin-related protein [General function prediction only]; Region: COG1741
585397011289	Pirin; Region: Pirin; pfam02678
585397011290	putative oxidoreductase; Provisional; Region: PRK10206
585397011291	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
585397011292	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
585397011293	putative acetyltransferase YhhY; Provisional; Region: PRK10140
585397011294	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585397011295	Coenzyme A binding pocket [chemical binding]; other site
585397011296	fragment of conserved hypothetical protein (part 1);Evidence 7 : Gene remnant
585397011297	fragment of conserved hypothetical protein (part 2);Evidence 7 : Gene remnant
585397011298	YopJ Serine/Threonine acetyltransferase; Region: YopJ; cl07849
585397011299	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
585397011300	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
585397011301	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
585397011302	hypothetical protein; Provisional; Region: PRK10350
585397011303	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
585397011304	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
585397011305	putative active site [active]
585397011306	catalytic site [active]
585397011307	putative metal binding site [ion binding]; other site
585397011308	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
585397011309	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
585397011310	Walker A/P-loop; other site
585397011311	ATP binding site [chemical binding]; other site
585397011312	Q-loop/lid; other site
585397011313	ABC transporter signature motif; other site
585397011314	Walker B; other site
585397011315	D-loop; other site
585397011316	H-loop/switch region; other site
585397011317	TOBE domain; Region: TOBE_2; pfam08402
585397011318	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
585397011319	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397011320	dimer interface [polypeptide binding]; other site
585397011321	conserved gate region; other site
585397011322	putative PBP binding loops; other site
585397011323	ABC-ATPase subunit interface; other site
585397011324	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
585397011325	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397011326	dimer interface [polypeptide binding]; other site
585397011327	conserved gate region; other site
585397011328	putative PBP binding loops; other site
585397011329	ABC-ATPase subunit interface; other site
585397011330	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
585397011331	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
585397011332	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
585397011333	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
585397011334	Walker A/P-loop; other site
585397011335	ATP binding site [chemical binding]; other site
585397011336	Q-loop/lid; other site
585397011337	ABC transporter signature motif; other site
585397011338	Walker B; other site
585397011339	D-loop; other site
585397011340	H-loop/switch region; other site
585397011341	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
585397011342	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
585397011343	Walker A/P-loop; other site
585397011344	ATP binding site [chemical binding]; other site
585397011345	Q-loop/lid; other site
585397011346	ABC transporter signature motif; other site
585397011347	Walker B; other site
585397011348	D-loop; other site
585397011349	H-loop/switch region; other site
585397011350	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
585397011351	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
585397011352	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
585397011353	TM-ABC transporter signature motif; other site
585397011354	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585397011355	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
585397011356	TM-ABC transporter signature motif; other site
585397011357	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
585397011358	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
585397011359	dimerization interface [polypeptide binding]; other site
585397011360	ligand binding site [chemical binding]; other site
585397011361	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
585397011362	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
585397011363	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
585397011364	dimerization interface [polypeptide binding]; other site
585397011365	ligand binding site [chemical binding]; other site
585397011366	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
585397011367	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
585397011368	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
585397011369	DNA binding residues [nucleotide binding]
585397011370	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
585397011371	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
585397011372	cell division protein FtsE; Provisional; Region: PRK10908
585397011373	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397011374	Walker A/P-loop; other site
585397011375	ATP binding site [chemical binding]; other site
585397011376	Q-loop/lid; other site
585397011377	ABC transporter signature motif; other site
585397011378	Walker B; other site
585397011379	D-loop; other site
585397011380	H-loop/switch region; other site
585397011381	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
585397011382	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
585397011383	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
585397011384	P loop; other site
585397011385	GTP binding site [chemical binding]; other site
585397011386	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
585397011387	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397011388	S-adenosylmethionine binding site [chemical binding]; other site
585397011389	hypothetical protein; Provisional; Region: PRK10910
585397011390	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
585397011391	Predicted membrane protein [Function unknown]; Region: COG3714
585397011392	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
585397011393	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
585397011394	metal-binding site [ion binding]
585397011395	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
585397011396	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
585397011397	CPxP  motif; other site
585397011398	hypothetical protein; Provisional; Region: PRK11212
585397011399	hypothetical protein; Provisional; Region: PRK11615
585397011400	major facilitator superfamily transporter; Provisional; Region: PRK05122
585397011401	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397011402	putative substrate translocation pore; other site
585397011403	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
585397011404	Domain of unknown function DUF20; Region: UPF0118; pfam01594
585397011405	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
585397011406	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
585397011407	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
585397011408	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
585397011409	substrate binding site [chemical binding]; other site
585397011410	nickel transporter permease NikB; Provisional; Region: PRK10352
585397011411	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397011412	dimer interface [polypeptide binding]; other site
585397011413	conserved gate region; other site
585397011414	putative PBP binding loops; other site
585397011415	ABC-ATPase subunit interface; other site
585397011416	nickel transporter permease NikC; Provisional; Region: nikC; PRK10417
585397011417	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397011418	dimer interface [polypeptide binding]; other site
585397011419	conserved gate region; other site
585397011420	putative PBP binding loops; other site
585397011421	ABC-ATPase subunit interface; other site
585397011422	nickel transporter ATP-binding protein NikD; Provisional; Region: nikD; PRK10418
585397011423	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585397011424	Walker A/P-loop; other site
585397011425	ATP binding site [chemical binding]; other site
585397011426	Q-loop/lid; other site
585397011427	ABC transporter signature motif; other site
585397011428	Walker B; other site
585397011429	D-loop; other site
585397011430	H-loop/switch region; other site
585397011431	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
585397011432	nickel transporter ATP-binding protein NikE; Provisional; Region: nikE; PRK10419
585397011433	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585397011434	Walker A/P-loop; other site
585397011435	ATP binding site [chemical binding]; other site
585397011436	Q-loop/lid; other site
585397011437	ABC transporter signature motif; other site
585397011438	Walker B; other site
585397011439	D-loop; other site
585397011440	H-loop/switch region; other site
585397011441	nickel responsive regulator; Provisional; Region: PRK02967
585397011442	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
585397011443	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
585397011444	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
585397011445	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
585397011446	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
585397011447	Walker A/P-loop; other site
585397011448	ATP binding site [chemical binding]; other site
585397011449	Q-loop/lid; other site
585397011450	ABC transporter signature motif; other site
585397011451	Walker B; other site
585397011452	D-loop; other site
585397011453	H-loop/switch region; other site
585397011454	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
585397011455	Walker A/P-loop; other site
585397011456	ATP binding site [chemical binding]; other site
585397011457	Q-loop/lid; other site
585397011458	ABC transporter signature motif; other site
585397011459	Walker B; other site
585397011460	D-loop; other site
585397011461	H-loop/switch region; other site
585397011462	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
585397011463	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
585397011464	HlyD family secretion protein; Region: HlyD; pfam00529
585397011465	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585397011466	HlyD family secretion protein; Region: HlyD_3; pfam13437
585397011467	Protein of unknown function (DUF2776); Region: DUF2776; pfam10951
585397011468	Predicted flavoproteins [General function prediction only]; Region: COG2081
585397011469	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
585397011470	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
585397011471	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
585397011472	universal stress protein UspB; Provisional; Region: PRK04960
585397011473	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
585397011474	Ligand Binding Site [chemical binding]; other site
585397011475	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
585397011476	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397011477	POT family; Region: PTR2; pfam00854
585397011478	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397011479	S-adenosylmethionine binding site [chemical binding]; other site
585397011480	oligopeptidase A; Provisional; Region: PRK10911
585397011481	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
585397011482	active site
585397011483	Zn binding site [ion binding]; other site
585397011484	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
585397011485	glutathione reductase; Validated; Region: PRK06116
585397011486	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
585397011487	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585397011488	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
585397011489	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
585397011490	ArsC family; Region: ArsC; pfam03960
585397011491	catalytic residues [active]
585397011492	fragment of conserved hypothetical protein (partial);Evidence 7 : Gene remnant
585397011493	outer membrane lipoprotein, Slp family; Region: slp; TIGR00752
585397011494	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
585397011495	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585397011496	DNA binding residues [nucleotide binding]
585397011497	dimerization interface [polypeptide binding]; other site
585397011498	Putative heme degradation protein [Inorganic ion transport and metabolism]; Region: HemS; COG3720
585397011499	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
585397011500	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
585397011501	fragment of outer membrane hemin receptor (part 2);Evidence 7 : Gene remnant; Product type t : transporter
585397011502	fragment of outer membrane hemin receptor (part 1);Evidence 7 : Gene remnant; Product type t : transporter
585397011503	ABC-type hemin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ChuT; COG4558
585397011504	Hemin binding protein HutB.  These proteins have been shown to function as initial receptors in ABC transport of hemin and hemoproteins in many eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a...; Region: HutB; cd01149
585397011505	putative hemin binding site; other site
585397011506	coproporphyrinogen III oxidase; Provisional; Region: PRK09058
585397011507	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585397011508	FeS/SAM binding site; other site
585397011509	Putative heme iron utilization protein [Inorganic ion transport and metabolism]; Region: HugX; COG3721
585397011510	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
585397011511	NADH(P)-binding; Region: NAD_binding_10; pfam13460
585397011512	NAD(P) binding site [chemical binding]; other site
585397011513	putative active site [active]
585397011514	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
585397011515	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
585397011516	ABC-ATPase subunit  interface; other site
585397011517	dimer interface [polypeptide binding]; other site
585397011518	putative PBP binding regions; other site
585397011519	ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG4559
585397011520	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
585397011521	Walker A/P-loop; other site
585397011522	ATP binding site [chemical binding]; other site
585397011523	Q-loop/lid; other site
585397011524	ABC transporter signature motif; other site
585397011525	Walker B; other site
585397011526	D-loop; other site
585397011527	H-loop/switch region; other site
585397011528	putative Mg(2+) transport ATPase; Provisional; Region: PRK09977
585397011529	MgtC family; Region: MgtC; pfam02308
585397011530	acid-resistance protein; Provisional; Region: hdeB; PRK11566
585397011531	acid-resistance protein; Provisional; Region: PRK10208
585397011532	acid-resistance membrane protein; Provisional; Region: PRK10209
585397011533	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
585397011534	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
585397011535	pyruvate kinase; Provisional; Region: PRK05826
585397011536	multidrug efflux system protein MdtE; Provisional; Region: PRK09859
585397011537	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585397011538	HlyD family secretion protein; Region: HlyD_3; pfam13437
585397011539	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
585397011540	Protein export membrane protein; Region: SecD_SecF; cl14618
585397011541	transcriptional regulator YdeO; Provisional; Region: PRK09940
585397011542	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397011543	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
585397011544	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397011545	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
585397011546	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397011547	catalytic residue [active]
585397011548	Haem-binding domain; Region: Haem_bd; pfam14376
585397011549	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
585397011550	trehalase; Provisional; Region: treF; PRK13270
585397011551	Trehalase; Region: Trehalase; pfam01204
585397011552	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
585397011553	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585397011554	DNA binding residues [nucleotide binding]
585397011555	dimerization interface [polypeptide binding]; other site
585397011556	Transcriptional regulator [Transcription]; Region: LysR; COG0583
585397011557	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397011558	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
585397011559	putative effector binding pocket; other site
585397011560	putative dimerization interface [polypeptide binding]; other site
585397011561	inner membrane protein YhjD; Region: TIGR00766
585397011562	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397011563	metabolite-proton symporter; Region: 2A0106; TIGR00883
585397011564	putative substrate translocation pore; other site
585397011565	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
585397011566	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
585397011567	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585397011568	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
585397011569	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
585397011570	substrate binding site [chemical binding]; other site
585397011571	ATP binding site [chemical binding]; other site
585397011572	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
585397011573	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
585397011574	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
585397011575	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
585397011576	putative diguanylate cyclase; Provisional; Region: PRK13561
585397011577	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585397011578	metal binding site [ion binding]; metal-binding site
585397011579	active site
585397011580	I-site; other site
585397011581	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585397011582	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
585397011583	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585397011584	binding surface
585397011585	TPR motif; other site
585397011586	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585397011587	binding surface
585397011588	TPR motif; other site
585397011589	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
585397011590	TPR motif; other site
585397011591	binding surface
585397011592	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
585397011593	endo-1,4-D-glucanase; Provisional; Region: PRK11097
585397011594	cellulose synthase regulator protein; Provisional; Region: PRK11114
585397011595	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
585397011596	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
585397011597	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
585397011598	DXD motif; other site
585397011599	PilZ domain; Region: PilZ; pfam07238
585397011600	cell division protein; Provisional; Region: PRK10037
585397011601	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
585397011602	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
585397011603	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
585397011604	celllulose biosynthesis operon protein BcsF/YhjT; Region: cellullose_BcsF; TIGR03493
585397011605	Protein of unknown function (DUF3260); Region: DUF3260; pfam11658
585397011606	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
585397011607	serine transporter; Region: stp; TIGR00814
585397011608	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
585397011609	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585397011610	Walker A/P-loop; other site
585397011611	ATP binding site [chemical binding]; other site
585397011612	Q-loop/lid; other site
585397011613	ABC transporter signature motif; other site
585397011614	Walker B; other site
585397011615	D-loop; other site
585397011616	H-loop/switch region; other site
585397011617	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
585397011618	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
585397011619	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585397011620	Walker A/P-loop; other site
585397011621	ATP binding site [chemical binding]; other site
585397011622	Q-loop/lid; other site
585397011623	ABC transporter signature motif; other site
585397011624	Walker B; other site
585397011625	D-loop; other site
585397011626	H-loop/switch region; other site
585397011627	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
585397011628	dipeptide transporter; Provisional; Region: PRK10913
585397011629	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
585397011630	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397011631	dimer interface [polypeptide binding]; other site
585397011632	conserved gate region; other site
585397011633	putative PBP binding loops; other site
585397011634	ABC-ATPase subunit interface; other site
585397011635	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
585397011636	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397011637	dimer interface [polypeptide binding]; other site
585397011638	conserved gate region; other site
585397011639	putative PBP binding loops; other site
585397011640	ABC-ATPase subunit interface; other site
585397011641	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
585397011642	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
585397011643	peptide binding site [polypeptide binding]; other site
585397011644	phosphoethanolamine transferase; Provisional; Region: PRK11560
585397011645	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
585397011646	Sulfatase; Region: Sulfatase; pfam00884
585397011647	long polar fimbrial protein LpfE; Provisional; Region: PRK15205
585397011648	Fimbrial protein; Region: Fimbrial; cl01416
585397011649	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397011650	Fimbrial protein; Region: Fimbrial; cl01416
585397011651	long polar fimbrial outer membrane usher protein LpfC; Provisional; Region: PRK15207
585397011652	PapC N-terminal domain; Region: PapC_N; pfam13954
585397011653	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585397011654	PapC C-terminal domain; Region: PapC_C; pfam13953
585397011655	long polar fimbrial chaperone LpfB; Provisional; Region: PRK15208
585397011656	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585397011657	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
585397011658	long polar fimbrial protein LpfA; Provisional; Region: PRK15209
585397011659	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
585397011660	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397011661	putative substrate translocation pore; other site
585397011662	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
585397011663	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
585397011664	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
585397011665	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585397011666	Coenzyme A binding pocket [chemical binding]; other site
585397011667	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
585397011668	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
585397011669	molybdopterin cofactor binding site [chemical binding]; other site
585397011670	substrate binding site [chemical binding]; other site
585397011671	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
585397011672	molybdopterin cofactor binding site; other site
585397011673	putative outer membrane lipoprotein; Provisional; Region: PRK10510
585397011674	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
585397011675	ligand binding site [chemical binding]; other site
585397011676	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
585397011677	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
585397011678	dimerization interface [polypeptide binding]; other site
585397011679	ligand binding site [chemical binding]; other site
585397011680	NADP binding site [chemical binding]; other site
585397011681	catalytic site [active]
585397011682	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
585397011683	Predicted transcriptional regulator [Transcription]; Region: COG2944
585397011684	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397011685	non-specific DNA binding site [nucleotide binding]; other site
585397011686	salt bridge; other site
585397011687	sequence-specific DNA binding site [nucleotide binding]; other site
585397011688	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
585397011689	DNA-binding site [nucleotide binding]; DNA binding site
585397011690	RNA-binding motif; other site
585397011691	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
585397011692	DALR anticodon binding domain; Region: DALR_1; pfam05746
585397011693	anticodon binding site; other site
585397011694	tRNA binding surface [nucleotide binding]; other site
585397011695	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
585397011696	dimer interface [polypeptide binding]; other site
585397011697	motif 1; other site
585397011698	active site
585397011699	motif 2; other site
585397011700	motif 3; other site
585397011701	YsaB-like lipoprotein; Region: YsaB; pfam13983
585397011702	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
585397011703	Acyltransferase family; Region: Acyl_transf_3; pfam01757
585397011704	fragment of conserved hypothetical protein; putative inner membrane protein (part 2);Evidence 7 : Gene remnant; Product type pm : putative membrane component
585397011705	fragment of conserved hypothetical protein; putative inner membrane protein (part 1);Evidence 7 : Gene remnant; Product type pm : putative membrane component
585397011706	hypothetical protein; Provisional; Region: PRK11403
585397011707	yiaA/B two helix domain; Region: YiaAB; pfam05360
585397011708	xylulokinase; Provisional; Region: PRK15027
585397011709	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
585397011710	N- and C-terminal domain interface [polypeptide binding]; other site
585397011711	active site
585397011712	MgATP binding site [chemical binding]; other site
585397011713	catalytic site [active]
585397011714	metal binding site [ion binding]; metal-binding site
585397011715	xylulose binding site [chemical binding]; other site
585397011716	homodimer interface [polypeptide binding]; other site
585397011717	xylose isomerase; Provisional; Region: PRK05474
585397011718	xylose isomerase; Region: xylose_isom_A; TIGR02630
585397011719	D-xylose transporter subunit XylF; Provisional; Region: xylF; PRK10355
585397011720	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
585397011721	putative ligand binding site [chemical binding]; other site
585397011722	fragment of fused D-xylose transporter subunits of ABC superfamily: ATP-binding components (part 1);Evidence 7 : Gene remnant; Product type t : transporter
585397011723	fragment of fused D-xylose transporter subunits of ABC superfamily: ATP-binding components (part 2);Evidence 7 : Gene remnant; Product type t : transporter
585397011724	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585397011725	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585397011726	TM-ABC transporter signature motif; other site
585397011727	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
585397011728	putative dimerization interface [polypeptide binding]; other site
585397011729	Transcriptional regulators [Transcription]; Region: PurR; COG1609
585397011730	putative ligand binding site [chemical binding]; other site
585397011731	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397011732	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
585397011733	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397011734	hypothetical protein; Provisional; Region: PRK10356
585397011735	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
585397011736	alpha-amylase; Reviewed; Region: malS; PRK09505
585397011737	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
585397011738	active site
585397011739	catalytic site [active]
585397011740	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
585397011741	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585397011742	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397011743	homodimer interface [polypeptide binding]; other site
585397011744	catalytic residue [active]
585397011745	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
585397011746	Transcriptional regulator [Transcription]; Region: IclR; COG1414
585397011747	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
585397011748	Bacterial transcriptional regulator; Region: IclR; pfam01614
585397011749	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
585397011750	Domain of unknown function (DUF386); Region: DUF386; pfam04074
585397011751	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
585397011752	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
585397011753	DctM-like transporters; Region: DctM; pfam06808
585397011754	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
585397011755	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
585397011756	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
585397011757	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
585397011758	putative N- and C-terminal domain interface [polypeptide binding]; other site
585397011759	putative active site [active]
585397011760	MgATP binding site [chemical binding]; other site
585397011761	catalytic site [active]
585397011762	metal binding site [ion binding]; metal-binding site
585397011763	putative xylulose binding site [chemical binding]; other site
585397011764	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
585397011765	active site
585397011766	dimer interface [polypeptide binding]; other site
585397011767	magnesium binding site [ion binding]; other site
585397011768	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
585397011769	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
585397011770	AP (apurinic/apyrimidinic) site pocket; other site
585397011771	DNA interaction; other site
585397011772	Metal-binding active site; metal-binding site
585397011773	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
585397011774	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
585397011775	intersubunit interface [polypeptide binding]; other site
585397011776	active site
585397011777	Zn2+ binding site [ion binding]; other site
585397011778	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
585397011779	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
585397011780	NAD(P) binding site [chemical binding]; other site
585397011781	catalytic residues [active]
585397011782	Fic family protein [Function unknown]; Region: COG3177
585397011783	Fic/DOC family; Region: Fic; pfam02661
585397011784	putative alcohol dehydrogenase; Provisional; Region: PRK09860
585397011785	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
585397011786	dimer interface [polypeptide binding]; other site
585397011787	active site
585397011788	metal binding site [ion binding]; metal-binding site
585397011789	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
585397011790	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
585397011791	G1 box; other site
585397011792	putative GEF interaction site [polypeptide binding]; other site
585397011793	GTP/Mg2+ binding site [chemical binding]; other site
585397011794	Switch I region; other site
585397011795	G2 box; other site
585397011796	G3 box; other site
585397011797	Switch II region; other site
585397011798	G4 box; other site
585397011799	G5 box; other site
585397011800	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
585397011801	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
585397011802	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
585397011803	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
585397011804	selenocysteine synthase; Provisional; Region: PRK04311
585397011805	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
585397011806	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
585397011807	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
585397011808	catalytic residue [active]
585397011809	putative glutathione S-transferase; Provisional; Region: PRK10357
585397011810	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
585397011811	putative C-terminal domain interface [polypeptide binding]; other site
585397011812	putative GSH binding site (G-site) [chemical binding]; other site
585397011813	putative dimer interface [polypeptide binding]; other site
585397011814	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
585397011815	dimer interface [polypeptide binding]; other site
585397011816	N-terminal domain interface [polypeptide binding]; other site
585397011817	putative substrate binding pocket (H-site) [chemical binding]; other site
585397011818	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
585397011819	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585397011820	HlyD family secretion protein; Region: HlyD_3; pfam13437
585397011821	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
585397011822	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
585397011823	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
585397011824	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
585397011825	active site
585397011826	P-loop; other site
585397011827	phosphorylation site [posttranslational modification]
585397011828	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
585397011829	active site
585397011830	phosphorylation site [posttranslational modification]
585397011831	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
585397011832	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
585397011833	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
585397011834	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
585397011835	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
585397011836	hypothetical protein; Provisional; Region: PRK11020
585397011837	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
585397011838	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
585397011839	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
585397011840	trimer interface [polypeptide binding]; other site
585397011841	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
585397011842	trimer interface [polypeptide binding]; other site
585397011843	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
585397011844	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
585397011845	Haemagglutinin; Region: HIM; pfam05662
585397011846	Haemagglutinin; Region: HIM; pfam05662
585397011847	YadA-like C-terminal region; Region: YadA; pfam03895
585397011848	L-lactate permease; Provisional; Region: PRK10420
585397011849	glycolate transporter; Provisional; Region: PRK09695
585397011850	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
585397011851	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585397011852	DNA-binding site [nucleotide binding]; DNA binding site
585397011853	FCD domain; Region: FCD; pfam07729
585397011854	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
585397011855	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
585397011856	phosphate binding site [ion binding]; other site
585397011857	putative rRNA methylase; Provisional; Region: PRK10358
585397011858	serine acetyltransferase; Provisional; Region: cysE; PRK11132
585397011859	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
585397011860	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
585397011861	trimer interface [polypeptide binding]; other site
585397011862	active site
585397011863	substrate binding site [chemical binding]; other site
585397011864	CoA binding site [chemical binding]; other site
585397011865	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
585397011866	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
585397011867	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
585397011868	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
585397011869	SecA binding site; other site
585397011870	Preprotein binding site; other site
585397011871	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
585397011872	GSH binding site [chemical binding]; other site
585397011873	catalytic residues [active]
585397011874	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
585397011875	active site residue [active]
585397011876	phosphoglyceromutase; Provisional; Region: PRK05434
585397011877	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
585397011878	AmiB activator; Provisional; Region: PRK11637
585397011879	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
585397011880	Peptidase family M23; Region: Peptidase_M23; pfam01551
585397011881	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
585397011882	NodB motif; other site
585397011883	putative active site [active]
585397011884	putative catalytic site [active]
585397011885	Zn binding site [ion binding]; other site
585397011886	putative glycosyl transferase; Provisional; Region: PRK10073
585397011887	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
585397011888	active site
585397011889	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
585397011890	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
585397011891	NAD(P) binding site [chemical binding]; other site
585397011892	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
585397011893	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
585397011894	substrate-cofactor binding pocket; other site
585397011895	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397011896	catalytic residue [active]
585397011897	hypothetical protein; Provisional; Region: PRK11346
585397011898	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
585397011899	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
585397011900	NADP binding site [chemical binding]; other site
585397011901	homopentamer interface [polypeptide binding]; other site
585397011902	substrate binding site [chemical binding]; other site
585397011903	active site
585397011904	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
585397011905	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
585397011906	putative active site [active]
585397011907	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
585397011908	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
585397011909	putative active site [active]
585397011910	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
585397011911	O-antigen ligase RfaL; Provisional; Region: PRK15487
585397011912	lipopolysaccharide 1,2-N-acetylglucosaminetransferase; Provisional; Region: PRK15484
585397011913	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
585397011914	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
585397011915	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
585397011916	Ligand binding site; other site
585397011917	metal-binding site
585397011918	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
585397011919	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; cl17526
585397011920	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
585397011921	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
585397011922	Ligand binding site; other site
585397011923	metal-binding site
585397011924	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
585397011925	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
585397011926	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
585397011927	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
585397011928	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
585397011929	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
585397011930	putative active site [active]
585397011931	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
585397011932	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
585397011933	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
585397011934	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
585397011935	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
585397011936	active site
585397011937	(T/H)XGH motif; other site
585397011938	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
585397011939	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
585397011940	DNA binding site [nucleotide binding]
585397011941	catalytic residue [active]
585397011942	H2TH interface [polypeptide binding]; other site
585397011943	putative catalytic residues [active]
585397011944	turnover-facilitating residue; other site
585397011945	intercalation triad [nucleotide binding]; other site
585397011946	8OG recognition residue [nucleotide binding]; other site
585397011947	putative reading head residues; other site
585397011948	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
585397011949	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
585397011950	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
585397011951	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
585397011952	hypothetical protein; Reviewed; Region: PRK00024
585397011953	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
585397011954	MPN+ (JAMM) motif; other site
585397011955	Zinc-binding site [ion binding]; other site
585397011956	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
585397011957	Flavoprotein; Region: Flavoprotein; pfam02441
585397011958	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
585397011959	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
585397011960	trimer interface [polypeptide binding]; other site
585397011961	active site
585397011962	division inhibitor protein; Provisional; Region: slmA; PRK09480
585397011963	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585397011964	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
585397011965	active site
585397011966	ribonuclease PH; Reviewed; Region: rph; PRK00173
585397011967	Ribonuclease PH; Region: RNase_PH_bact; cd11362
585397011968	hexamer interface [polypeptide binding]; other site
585397011969	active site
585397011970	hypothetical protein; Provisional; Region: PRK11820
585397011971	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
585397011972	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
585397011973	Predicted membrane protein [Function unknown]; Region: COG2860
585397011974	UPF0126 domain; Region: UPF0126; pfam03458
585397011975	UPF0126 domain; Region: UPF0126; pfam03458
585397011976	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
585397011977	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
585397011978	nucleotide binding pocket [chemical binding]; other site
585397011979	K-X-D-G motif; other site
585397011980	catalytic site [active]
585397011981	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
585397011982	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
585397011983	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
585397011984	catalytic site [active]
585397011985	G-X2-G-X-G-K; other site
585397011986	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
585397011987	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
585397011988	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
585397011989	Zn2+ binding site [ion binding]; other site
585397011990	Mg2+ binding site [ion binding]; other site
585397011991	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
585397011992	synthetase active site [active]
585397011993	NTP binding site [chemical binding]; other site
585397011994	metal binding site [ion binding]; metal-binding site
585397011995	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
585397011996	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
585397011997	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
585397011998	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
585397011999	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
585397012000	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
585397012001	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
585397012002	generic binding surface II; other site
585397012003	ssDNA binding site; other site
585397012004	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585397012005	ATP binding site [chemical binding]; other site
585397012006	putative Mg++ binding site [ion binding]; other site
585397012007	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585397012008	nucleotide binding region [chemical binding]; other site
585397012009	ATP-binding site [chemical binding]; other site
585397012010	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
585397012011	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
585397012012	AsmA family; Region: AsmA; pfam05170
585397012013	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
585397012014	Protein of unknown function (DUF1498); Region: DUF1498; pfam07385
585397012015	fructokinase; Reviewed; Region: PRK09557
585397012016	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
585397012017	nucleotide binding site [chemical binding]; other site
585397012018	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
585397012019	intersubunit interface [polypeptide binding]; other site
585397012020	active site
585397012021	zinc binding site [ion binding]; other site
585397012022	Na+ binding site [ion binding]; other site
585397012023	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
585397012024	intersubunit interface [polypeptide binding]; other site
585397012025	active site
585397012026	zinc binding site [ion binding]; other site
585397012027	Na+ binding site [ion binding]; other site
585397012028	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
585397012029	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
585397012030	active site
585397012031	P-loop; other site
585397012032	phosphorylation site [posttranslational modification]
585397012033	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
585397012034	active site
585397012035	phosphorylation site [posttranslational modification]
585397012036	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
585397012037	HTH domain; Region: HTH_11; pfam08279
585397012038	Mga helix-turn-helix domain; Region: Mga; pfam05043
585397012039	PRD domain; Region: PRD; pfam00874
585397012040	PRD domain; Region: PRD; pfam00874
585397012041	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
585397012042	active site
585397012043	P-loop; other site
585397012044	phosphorylation site [posttranslational modification]
585397012045	putative alpha-glucosidase; Provisional; Region: PRK10658
585397012046	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
585397012047	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
585397012048	active site
585397012049	homotrimer interface [polypeptide binding]; other site
585397012050	catalytic site [active]
585397012051	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
585397012052	putative transporter; Provisional; Region: PRK11462
585397012053	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
585397012054	Virulence protein [General function prediction only]; Region: COG3943
585397012055	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
585397012056	EamA-like transporter family; Region: EamA; pfam00892
585397012057	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
585397012058	EamA-like transporter family; Region: EamA; pfam00892
585397012059	cytoplasmic membrane lipoprotein-28; Provisional; Region: PRK09861
585397012060	lipoprotein, YaeC family; Region: TIGR00363
585397012061	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
585397012062	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397012063	putative substrate translocation pore; other site
585397012064	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
585397012065	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
585397012066	cryptic adenine deaminase; Provisional; Region: PRK10027
585397012067	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
585397012068	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
585397012069	active site
585397012070	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
585397012071	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
585397012072	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397012073	putative substrate translocation pore; other site
585397012074	regulatory protein UhpC; Provisional; Region: PRK11663
585397012075	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397012076	putative substrate translocation pore; other site
585397012077	sensory histidine kinase UhpB; Provisional; Region: PRK11644
585397012078	MASE1; Region: MASE1; pfam05231
585397012079	Histidine kinase; Region: HisKA_3; pfam07730
585397012080	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397012081	ATP binding site [chemical binding]; other site
585397012082	Mg2+ binding site [ion binding]; other site
585397012083	G-X-G motif; other site
585397012084	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
585397012085	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397012086	active site
585397012087	phosphorylation site [posttranslational modification]
585397012088	intermolecular recognition site; other site
585397012089	dimerization interface [polypeptide binding]; other site
585397012090	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585397012091	DNA binding residues [nucleotide binding]
585397012092	dimerization interface [polypeptide binding]; other site
585397012093	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
585397012094	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
585397012095	putative valine binding site [chemical binding]; other site
585397012096	dimer interface [polypeptide binding]; other site
585397012097	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
585397012098	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
585397012099	PYR/PP interface [polypeptide binding]; other site
585397012100	dimer interface [polypeptide binding]; other site
585397012101	TPP binding site [chemical binding]; other site
585397012102	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
585397012103	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
585397012104	TPP-binding site [chemical binding]; other site
585397012105	dimer interface [polypeptide binding]; other site
585397012106	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
585397012107	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397012108	putative substrate translocation pore; other site
585397012109	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
585397012110	Domain of unknown function (DUF202); Region: DUF202; pfam02656
585397012111	Predicted membrane protein [Function unknown]; Region: COG2149
585397012112	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
585397012113	Sulfatase; Region: Sulfatase; pfam00884
585397012114	putative transporter; Provisional; Region: PRK10484
585397012115	uncharacterized SLC5 subfamily, Escherichia coli YidK-like; solute binding domain; Region: SLC5sbd_YidK; cd10328
585397012116	Na binding site [ion binding]; other site
585397012117	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
585397012118	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397012119	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
585397012120	putative transporter; Validated; Region: PRK03818
585397012121	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
585397012122	TrkA-C domain; Region: TrkA_C; pfam02080
585397012123	TrkA-C domain; Region: TrkA_C; pfam02080
585397012124	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
585397012125	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
585397012126	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
585397012127	putative dimer interface [polypeptide binding]; other site
585397012128	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
585397012129	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
585397012130	putative dimer interface [polypeptide binding]; other site
585397012131	hypothetical protein; Provisional; Region: PRK11616
585397012132	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
585397012133	putative oxidoreductase; Provisional; Region: PRK11445
585397012134	hypothetical protein; Provisional; Region: PRK07236
585397012135	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397012136	D-galactonate transporter; Region: 2A0114; TIGR00893
585397012137	putative substrate translocation pore; other site
585397012138	galactonate dehydratase; Provisional; Region: PRK14017
585397012139	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
585397012140	putative active site pocket [active]
585397012141	putative metal binding site [ion binding]; other site
585397012142	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
585397012143	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
585397012144	active site
585397012145	intersubunit interface [polypeptide binding]; other site
585397012146	catalytic residue [active]
585397012147	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
585397012148	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
585397012149	Transcriptional regulators [Transcription]; Region: FadR; COG2186
585397012150	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585397012151	DNA-binding site [nucleotide binding]; DNA binding site
585397012152	FCD domain; Region: FCD; pfam07729
585397012153	hypothetical protein; Provisional; Region: PRK10215
585397012154	sugar phosphate phosphatase; Provisional; Region: PRK10513
585397012155	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397012156	active site
585397012157	motif I; other site
585397012158	motif II; other site
585397012159	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397012160	hypothetical protein; Provisional; Region: PRK11426
585397012161	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
585397012162	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397012163	Mg2+ binding site [ion binding]; other site
585397012164	G-X-G motif; other site
585397012165	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
585397012166	anchoring element; other site
585397012167	dimer interface [polypeptide binding]; other site
585397012168	ATP binding site [chemical binding]; other site
585397012169	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
585397012170	active site
585397012171	putative metal-binding site [ion binding]; other site
585397012172	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
585397012173	recF protein; Region: recf; TIGR00611
585397012174	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397012175	Walker A/P-loop; other site
585397012176	ATP binding site [chemical binding]; other site
585397012177	Q-loop/lid; other site
585397012178	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397012179	ABC transporter signature motif; other site
585397012180	Walker B; other site
585397012181	D-loop; other site
585397012182	H-loop/switch region; other site
585397012183	DNA polymerase III subunit beta; Validated; Region: PRK05643
585397012184	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
585397012185	putative DNA binding surface [nucleotide binding]; other site
585397012186	dimer interface [polypeptide binding]; other site
585397012187	beta-clamp/clamp loader binding surface; other site
585397012188	beta-clamp/translesion DNA polymerase binding surface; other site
585397012189	DnaA N-terminal domain; Region: DnaA_N; pfam11638
585397012190	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
585397012191	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397012192	Walker A motif; other site
585397012193	ATP binding site [chemical binding]; other site
585397012194	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
585397012195	Walker B motif; other site
585397012196	arginine finger; other site
585397012197	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
585397012198	DnaA box-binding interface [nucleotide binding]; other site
585397012199	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
585397012200	ribonuclease P; Reviewed; Region: rnpA; PRK01732
585397012201	hypothetical protein; Validated; Region: PRK00041
585397012202	membrane protein insertase; Provisional; Region: PRK01318
585397012203	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
585397012204	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
585397012205	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
585397012206	trmE is a tRNA modification GTPase; Region: trmE; cd04164
585397012207	G1 box; other site
585397012208	GTP/Mg2+ binding site [chemical binding]; other site
585397012209	Switch I region; other site
585397012210	G2 box; other site
585397012211	Switch II region; other site
585397012212	G3 box; other site
585397012213	G4 box; other site
585397012214	G5 box; other site
585397012215	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
585397012216	Tryptophanese operon leader peptide; Region: Tna_leader; pfam08053
585397012217	tryptophanase, leader peptide-associated; Region: tnaA_trp_ase; TIGR02617
585397012218	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
585397012219	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
585397012220	catalytic residue [active]
585397012221	tryptophan permease TnaB; Provisional; Region: PRK09664
585397012222	aromatic amino acid transport protein; Region: araaP; TIGR00837
585397012223	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
585397012224	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397012225	putative substrate translocation pore; other site
585397012226	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
585397012227	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397012228	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
585397012229	substrate binding pocket [chemical binding]; other site
585397012230	dimerization interface [polypeptide binding]; other site
585397012231	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
585397012232	Predicted flavoprotein [General function prediction only]; Region: COG0431
585397012233	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
585397012234	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
585397012235	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
585397012236	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397012237	active site
585397012238	motif I; other site
585397012239	motif II; other site
585397012240	putative inner membrane protein; Provisional; Region: PRK09823
585397012241	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
585397012242	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
585397012243	active site
585397012244	trimer interface [polypeptide binding]; other site
585397012245	allosteric site; other site
585397012246	active site lid [active]
585397012247	N-terminal Early set domain associated with the catalytic domain of putative esterases; Region: E_set_Esterase_like_N; cd11294
585397012248	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
585397012249	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
585397012250	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
585397012251	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
585397012252	trimer interface; other site
585397012253	sugar binding site [chemical binding]; other site
585397012254	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
585397012255	beta-galactosidase; Region: BGL; TIGR03356
585397012256	PTS system beta-glucoside-specific transporter subunits IIABC; Provisional; Region: PRK09824
585397012257	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
585397012258	active site turn [active]
585397012259	phosphorylation site [posttranslational modification]
585397012260	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
585397012261	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
585397012262	HPr interaction site; other site
585397012263	glycerol kinase (GK) interaction site [polypeptide binding]; other site
585397012264	active site
585397012265	phosphorylation site [posttranslational modification]
585397012266	transcriptional antiterminator BglG; Provisional; Region: PRK09772
585397012267	CAT RNA binding domain; Region: CAT_RBD; pfam03123
585397012268	PRD domain; Region: PRD; pfam00874
585397012269	PRD domain; Region: PRD; pfam00874
585397012270	transcriptional regulator PhoU; Provisional; Region: PRK11115
585397012271	PhoU domain; Region: PhoU; pfam01895
585397012272	PhoU domain; Region: PhoU; pfam01895
585397012273	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
585397012274	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
585397012275	Walker A/P-loop; other site
585397012276	ATP binding site [chemical binding]; other site
585397012277	Q-loop/lid; other site
585397012278	ABC transporter signature motif; other site
585397012279	Walker B; other site
585397012280	D-loop; other site
585397012281	H-loop/switch region; other site
585397012282	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
585397012283	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397012284	dimer interface [polypeptide binding]; other site
585397012285	conserved gate region; other site
585397012286	putative PBP binding loops; other site
585397012287	ABC-ATPase subunit interface; other site
585397012288	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
585397012289	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397012290	dimer interface [polypeptide binding]; other site
585397012291	conserved gate region; other site
585397012292	putative PBP binding loops; other site
585397012293	ABC-ATPase subunit interface; other site
585397012294	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585397012295	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
585397012296	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
585397012297	glutaminase active site [active]
585397012298	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
585397012299	dimer interface [polypeptide binding]; other site
585397012300	active site
585397012301	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
585397012302	dimer interface [polypeptide binding]; other site
585397012303	active site
585397012304	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
585397012305	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
585397012306	Substrate binding site; other site
585397012307	Mg++ binding site; other site
585397012308	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
585397012309	active site
585397012310	substrate binding site [chemical binding]; other site
585397012311	CoA binding site [chemical binding]; other site
585397012312	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
585397012313	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
585397012314	gamma subunit interface [polypeptide binding]; other site
585397012315	epsilon subunit interface [polypeptide binding]; other site
585397012316	LBP interface [polypeptide binding]; other site
585397012317	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
585397012318	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
585397012319	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
585397012320	alpha subunit interaction interface [polypeptide binding]; other site
585397012321	Walker A motif; other site
585397012322	ATP binding site [chemical binding]; other site
585397012323	Walker B motif; other site
585397012324	inhibitor binding site; inhibition site
585397012325	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
585397012326	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
585397012327	core domain interface [polypeptide binding]; other site
585397012328	delta subunit interface [polypeptide binding]; other site
585397012329	epsilon subunit interface [polypeptide binding]; other site
585397012330	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
585397012331	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
585397012332	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
585397012333	beta subunit interaction interface [polypeptide binding]; other site
585397012334	Walker A motif; other site
585397012335	ATP binding site [chemical binding]; other site
585397012336	Walker B motif; other site
585397012337	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
585397012338	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
585397012339	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
585397012340	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
585397012341	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
585397012342	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
585397012343	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
585397012344	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
585397012345	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
585397012346	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
585397012347	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397012348	S-adenosylmethionine binding site [chemical binding]; other site
585397012349	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
585397012350	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
585397012351	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
585397012352	FMN-binding protein MioC; Provisional; Region: PRK09004
585397012353	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
585397012354	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
585397012355	putative DNA binding site [nucleotide binding]; other site
585397012356	putative Zn2+ binding site [ion binding]; other site
585397012357	AsnC family; Region: AsnC_trans_reg; pfam01037
585397012358	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
585397012359	dimer interface [polypeptide binding]; other site
585397012360	active site
585397012361	hypothetical protein; Provisional; Region: yieM; PRK10997
585397012362	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
585397012363	metal ion-dependent adhesion site (MIDAS); other site
585397012364	regulatory ATPase RavA; Provisional; Region: PRK13531
585397012365	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397012366	Walker A motif; other site
585397012367	ATP binding site [chemical binding]; other site
585397012368	Walker B motif; other site
585397012369	arginine finger; other site
585397012370	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
585397012371	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
585397012372	potassium uptake protein; Region: kup; TIGR00794
585397012373	D-ribose pyranase; Provisional; Region: PRK11797
585397012374	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
585397012375	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
585397012376	Walker A/P-loop; other site
585397012377	ATP binding site [chemical binding]; other site
585397012378	Q-loop/lid; other site
585397012379	ABC transporter signature motif; other site
585397012380	Walker B; other site
585397012381	D-loop; other site
585397012382	H-loop/switch region; other site
585397012383	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
585397012384	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585397012385	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585397012386	TM-ABC transporter signature motif; other site
585397012387	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
585397012388	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
585397012389	ligand binding site [chemical binding]; other site
585397012390	dimerization interface [polypeptide binding]; other site
585397012391	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
585397012392	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
585397012393	substrate binding site [chemical binding]; other site
585397012394	dimer interface [polypeptide binding]; other site
585397012395	ATP binding site [chemical binding]; other site
585397012396	transcriptional repressor RbsR; Provisional; Region: PRK10423
585397012397	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585397012398	DNA binding site [nucleotide binding]
585397012399	domain linker motif; other site
585397012400	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
585397012401	dimerization interface [polypeptide binding]; other site
585397012402	ligand binding site [chemical binding]; other site
585397012403	putative transporter; Provisional; Region: PRK10504
585397012404	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397012405	putative substrate translocation pore; other site
585397012406	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397012407	Transcriptional regulators [Transcription]; Region: FadR; COG2186
585397012408	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585397012409	DNA-binding site [nucleotide binding]; DNA binding site
585397012410	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
585397012411	transcriptional regulator HdfR; Provisional; Region: PRK03601
585397012412	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397012413	LysR substrate binding domain; Region: LysR_substrate; pfam03466
585397012414	dimerization interface [polypeptide binding]; other site
585397012415	hypothetical protein; Provisional; Region: PRK11027
585397012416	putative ATP-dependent protease; Provisional; Region: PRK09862
585397012417	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
585397012418	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397012419	Walker A motif; other site
585397012420	ATP binding site [chemical binding]; other site
585397012421	Walker B motif; other site
585397012422	arginine finger; other site
585397012423	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
585397012424	ilvG operon leader peptide; Provisional; Region: PRK10424
585397012425	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
585397012426	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
585397012427	PYR/PP interface [polypeptide binding]; other site
585397012428	dimer interface [polypeptide binding]; other site
585397012429	TPP binding site [chemical binding]; other site
585397012430	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
585397012431	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
585397012432	TPP-binding site [chemical binding]; other site
585397012433	dimer interface [polypeptide binding]; other site
585397012434	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
585397012435	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
585397012436	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
585397012437	homodimer interface [polypeptide binding]; other site
585397012438	substrate-cofactor binding pocket; other site
585397012439	catalytic residue [active]
585397012440	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
585397012441	threonine dehydratase; Reviewed; Region: PRK09224
585397012442	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
585397012443	tetramer interface [polypeptide binding]; other site
585397012444	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397012445	catalytic residue [active]
585397012446	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
585397012447	putative Ile/Val binding site [chemical binding]; other site
585397012448	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
585397012449	putative Ile/Val binding site [chemical binding]; other site
585397012450	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397012451	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
585397012452	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
585397012453	putative dimerization interface [polypeptide binding]; other site
585397012454	ketol-acid reductoisomerase; Validated; Region: PRK05225
585397012455	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
585397012456	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
585397012457	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
585397012458	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
585397012459	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
585397012460	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
585397012461	Part of AAA domain; Region: AAA_19; pfam13245
585397012462	Family description; Region: UvrD_C_2; pfam13538
585397012463	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
585397012464	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
585397012465	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
585397012466	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
585397012467	ATP binding site [chemical binding]; other site
585397012468	Mg++ binding site [ion binding]; other site
585397012469	motif III; other site
585397012470	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585397012471	nucleotide binding region [chemical binding]; other site
585397012472	ATP-binding site [chemical binding]; other site
585397012473	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
585397012474	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
585397012475	catalytic residues [active]
585397012476	putative rho operon leader peptide; Provisional; Region: PRK09979
585397012477	transcription termination factor Rho; Provisional; Region: rho; PRK09376
585397012478	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
585397012479	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
585397012480	RNA binding site [nucleotide binding]; other site
585397012481	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
585397012482	multimer interface [polypeptide binding]; other site
585397012483	Walker A motif; other site
585397012484	ATP binding site [chemical binding]; other site
585397012485	Walker B motif; other site
585397012486	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
585397012487	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
585397012488	Mg++ binding site [ion binding]; other site
585397012489	putative catalytic motif [active]
585397012490	substrate binding site [chemical binding]; other site
585397012491	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
585397012492	Chain length determinant protein; Region: Wzz; pfam02706
585397012493	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
585397012494	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
585397012495	active site
585397012496	homodimer interface [polypeptide binding]; other site
585397012497	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
585397012498	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
585397012499	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
585397012500	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
585397012501	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
585397012502	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
585397012503	NAD binding site [chemical binding]; other site
585397012504	substrate binding site [chemical binding]; other site
585397012505	homodimer interface [polypeptide binding]; other site
585397012506	active site
585397012507	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
585397012508	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
585397012509	substrate binding site; other site
585397012510	tetramer interface; other site
585397012511	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
585397012512	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
585397012513	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
585397012514	inhibitor-cofactor binding pocket; inhibition site
585397012515	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397012516	catalytic residue [active]
585397012517	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
585397012518	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
585397012519	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
585397012520	putative common antigen polymerase; Provisional; Region: PRK02975
585397012521	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
585397012522	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
585397012523	putative transport protein YifK; Provisional; Region: PRK10746
585397012524	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
585397012525	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585397012526	FeS/SAM binding site; other site
585397012527	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
585397012528	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
585397012529	Sulfatase; Region: Sulfatase; pfam00884
585397012530	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
585397012531	HemY protein N-terminus; Region: HemY_N; pfam07219
585397012532	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
585397012533	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
585397012534	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
585397012535	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
585397012536	active site
585397012537	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
585397012538	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
585397012539	domain interfaces; other site
585397012540	active site
585397012541	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
585397012542	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
585397012543	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
585397012544	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
585397012545	putative iron binding site [ion binding]; other site
585397012546	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
585397012547	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
585397012548	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
585397012549	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
585397012550	hypothetical protein; Provisional; Region: PRK10963
585397012551	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
585397012552	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
585397012553	active site
585397012554	DNA binding site [nucleotide binding]
585397012555	Int/Topo IB signature motif; other site
585397012556	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
585397012557	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397012558	motif II; other site
585397012559	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
585397012560	Part of AAA domain; Region: AAA_19; pfam13245
585397012561	Family description; Region: UvrD_C_2; pfam13538
585397012562	Uncharacterized conserved protein [Function unknown]; Region: COG1912
585397012563	Predicted periplasmic protein [Function unknown]; Region: COG3698
585397012564	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
585397012565	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
585397012566	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
585397012567	Cl binding site [ion binding]; other site
585397012568	oligomer interface [polypeptide binding]; other site
585397012569	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
585397012570	Protein of unknown function (DUF3289); Region: DUF3289; cl11840
585397012571	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
585397012572	EamA-like transporter family; Region: EamA; cl17759
585397012573	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
585397012574	CoenzymeA binding site [chemical binding]; other site
585397012575	subunit interaction site [polypeptide binding]; other site
585397012576	PHB binding site; other site
585397012577	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
585397012578	dimerization interface [polypeptide binding]; other site
585397012579	substrate binding site [chemical binding]; other site
585397012580	active site
585397012581	calcium binding site [ion binding]; other site
585397012582	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
585397012583	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585397012584	ATP binding site [chemical binding]; other site
585397012585	putative Mg++ binding site [ion binding]; other site
585397012586	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585397012587	nucleotide binding region [chemical binding]; other site
585397012588	ATP-binding site [chemical binding]; other site
585397012589	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
585397012590	Helicase and RNase D C-terminal; Region: HRDC; smart00341
585397012591	threonine efflux system; Provisional; Region: PRK10229
585397012592	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
585397012593	lysophospholipase L2; Provisional; Region: PRK10749
585397012594	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
585397012595	putative hydrolase; Provisional; Region: PRK10976
585397012596	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397012597	active site
585397012598	motif I; other site
585397012599	motif II; other site
585397012600	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397012601	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
585397012602	EamA-like transporter family; Region: EamA; pfam00892
585397012603	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
585397012604	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397012605	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
585397012606	putative dimerization interface [polypeptide binding]; other site
585397012607	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
585397012608	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
585397012609	THF binding site; other site
585397012610	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
585397012611	substrate binding site [chemical binding]; other site
585397012612	THF binding site; other site
585397012613	zinc-binding site [ion binding]; other site
585397012614	Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with...; Region: SIS_PHI; cd05005
585397012615	tetramer interface [polypeptide binding]; other site
585397012616	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
585397012617	active site
585397012618	PTS system, N-acetylglucosamine-specific IIBC component; Region: PTS-II-BC-nag; TIGR01998
585397012619	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
585397012620	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
585397012621	active site turn [active]
585397012622	phosphorylation site [posttranslational modification]
585397012623	transketolase; Reviewed; Region: PRK12753
585397012624	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
585397012625	TPP-binding site [chemical binding]; other site
585397012626	dimer interface [polypeptide binding]; other site
585397012627	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
585397012628	PYR/PP interface [polypeptide binding]; other site
585397012629	dimer interface [polypeptide binding]; other site
585397012630	TPP binding site [chemical binding]; other site
585397012631	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
585397012632	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
585397012633	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
585397012634	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
585397012635	putative active site [active]
585397012636	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
585397012637	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397012638	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
585397012639	dimerization interface [polypeptide binding]; other site
585397012640	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
585397012641	Na binding site [ion binding]; other site
585397012642	allophanate hydrolase; Provisional; Region: PRK08186
585397012643	carbamate kinase; Reviewed; Region: PRK12686
585397012644	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
585397012645	putative substrate binding site [chemical binding]; other site
585397012646	nucleotide binding site [chemical binding]; other site
585397012647	nucleotide binding site [chemical binding]; other site
585397012648	homodimer interface [polypeptide binding]; other site
585397012649	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
585397012650	CoA binding domain; Region: CoA_binding; pfam02629
585397012651	CoA-ligase; Region: Ligase_CoA; pfam00549
585397012652	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
585397012653	Isochorismatase family; Region: Isochorismatase; pfam00857
585397012654	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
585397012655	catalytic triad [active]
585397012656	conserved cis-peptide bond; other site
585397012657	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
585397012658	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
585397012659	uridine phosphorylase; Provisional; Region: PRK11178
585397012660	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
585397012661	Tripartite tricarboxylate transporter TctA family; Region: TctA; cl00772
585397012662	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
585397012663	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
585397012664	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
585397012665	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
585397012666	active site
585397012667	intersubunit interface [polypeptide binding]; other site
585397012668	catalytic residue [active]
585397012669	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
585397012670	Transcriptional regulator [Transcription]; Region: IclR; COG1414
585397012671	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
585397012672	Bacterial transcriptional regulator; Region: IclR; pfam01614
585397012673	DNA recombination protein RmuC; Provisional; Region: PRK10361
585397012674	RmuC family; Region: RmuC; pfam02646
585397012675	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
585397012676	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397012677	S-adenosylmethionine binding site [chemical binding]; other site
585397012678	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
585397012679	SCP-2 sterol transfer family; Region: SCP2; pfam02036
585397012680	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
585397012681	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
585397012682	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
585397012683	twin arginine translocase protein A; Provisional; Region: tatA; PRK00575
585397012684	sec-independent translocase; Provisional; Region: PRK01770
585397012685	sec-independent translocase; Provisional; Region: tatB; PRK00404
585397012686	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
585397012687	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
585397012688	active site
585397012689	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
585397012690	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
585397012691	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
585397012692	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
585397012693	FMN reductase; Validated; Region: fre; PRK08051
585397012694	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
585397012695	FAD binding pocket [chemical binding]; other site
585397012696	FAD binding motif [chemical binding]; other site
585397012697	phosphate binding motif [ion binding]; other site
585397012698	beta-alpha-beta structure motif; other site
585397012699	NAD binding pocket [chemical binding]; other site
585397012700	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
585397012701	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
585397012702	dimer interface [polypeptide binding]; other site
585397012703	active site
585397012704	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
585397012705	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
585397012706	substrate binding site [chemical binding]; other site
585397012707	oxyanion hole (OAH) forming residues; other site
585397012708	trimer interface [polypeptide binding]; other site
585397012709	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
585397012710	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
585397012711	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
585397012712	proline dipeptidase; Provisional; Region: PRK13607
585397012713	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
585397012714	active site
585397012715	hypothetical protein; Provisional; Region: PRK11568
585397012716	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
585397012717	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
585397012718	potassium transporter; Provisional; Region: PRK10750
585397012719	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
585397012720	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
585397012721	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
585397012722	Walker A motif; other site
585397012723	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
585397012724	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
585397012725	GTP binding site; other site
585397012726	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
585397012727	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
585397012728	serine/threonine protein kinase; Provisional; Region: PRK11768
585397012729	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
585397012730	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
585397012731	catalytic residues [active]
585397012732	hinge region; other site
585397012733	alpha helical domain; other site
585397012734	hypothetical protein; Provisional; Region: PRK11367
585397012735	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
585397012736	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
585397012737	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
585397012738	putative acyl-acceptor binding pocket; other site
585397012739	DNA polymerase I; Provisional; Region: PRK05755
585397012740	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
585397012741	active site
585397012742	metal binding site 1 [ion binding]; metal-binding site
585397012743	putative 5' ssDNA interaction site; other site
585397012744	metal binding site 3; metal-binding site
585397012745	metal binding site 2 [ion binding]; metal-binding site
585397012746	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
585397012747	putative DNA binding site [nucleotide binding]; other site
585397012748	putative metal binding site [ion binding]; other site
585397012749	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
585397012750	active site
585397012751	catalytic site [active]
585397012752	substrate binding site [chemical binding]; other site
585397012753	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
585397012754	active site
585397012755	DNA binding site [nucleotide binding]
585397012756	catalytic site [active]
585397012757	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
585397012758	G1 box; other site
585397012759	GTP/Mg2+ binding site [chemical binding]; other site
585397012760	Switch I region; other site
585397012761	G2 box; other site
585397012762	G3 box; other site
585397012763	Switch II region; other site
585397012764	G4 box; other site
585397012765	G5 box; other site
585397012766	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
585397012767	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
585397012768	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585397012769	FeS/SAM binding site; other site
585397012770	HemN C-terminal domain; Region: HemN_C; pfam06969
585397012771	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
585397012772	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397012773	active site
585397012774	phosphorylation site [posttranslational modification]
585397012775	intermolecular recognition site; other site
585397012776	dimerization interface [polypeptide binding]; other site
585397012777	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397012778	Walker A motif; other site
585397012779	ATP binding site [chemical binding]; other site
585397012780	Walker B motif; other site
585397012781	arginine finger; other site
585397012782	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
585397012783	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
585397012784	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585397012785	putative active site [active]
585397012786	heme pocket [chemical binding]; other site
585397012787	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585397012788	dimer interface [polypeptide binding]; other site
585397012789	phosphorylation site [posttranslational modification]
585397012790	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397012791	ATP binding site [chemical binding]; other site
585397012792	Mg2+ binding site [ion binding]; other site
585397012793	G-X-G motif; other site
585397012794	glutamine synthetase; Provisional; Region: glnA; PRK09469
585397012795	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
585397012796	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
585397012797	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
585397012798	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
585397012799	G1 box; other site
585397012800	putative GEF interaction site [polypeptide binding]; other site
585397012801	GTP/Mg2+ binding site [chemical binding]; other site
585397012802	Switch I region; other site
585397012803	G2 box; other site
585397012804	G3 box; other site
585397012805	Switch II region; other site
585397012806	G4 box; other site
585397012807	G5 box; other site
585397012808	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
585397012809	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
585397012810	outer membrane porin L; Provisional; Region: ompL; PRK09980
585397012811	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
585397012812	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397012813	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
585397012814	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
585397012815	alpha-glucosidase; Provisional; Region: PRK10426
585397012816	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
585397012817	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
585397012818	putative active site [active]
585397012819	putative catalytic site [active]
585397012820	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
585397012821	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
585397012822	active site
585397012823	catalytic residues [active]
585397012824	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
585397012825	dimerization interface [polypeptide binding]; other site
585397012826	putative active cleft [active]
585397012827	Class I aldolases; Region: Aldolase_Class_I; cl17187
585397012828	catalytic residue [active]
585397012829	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
585397012830	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
585397012831	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
585397012832	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
585397012833	substrate binding site [chemical binding]; other site
585397012834	ATP binding site [chemical binding]; other site
585397012835	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
585397012836	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
585397012837	putative DNA binding site [nucleotide binding]; other site
585397012838	putative Zn2+ binding site [ion binding]; other site
585397012839	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585397012840	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
585397012841	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397012842	motif II; other site
585397012843	hypothetical protein; Reviewed; Region: PRK01637
585397012844	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
585397012845	putative active site [active]
585397012846	dimerization interface [polypeptide binding]; other site
585397012847	putative tRNAtyr binding site [nucleotide binding]; other site
585397012848	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585397012849	Coenzyme A binding pocket [chemical binding]; other site
585397012850	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
585397012851	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
585397012852	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
585397012853	substrate binding pocket [chemical binding]; other site
585397012854	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397012855	non-specific DNA binding site [nucleotide binding]; other site
585397012856	salt bridge; other site
585397012857	sequence-specific DNA binding site [nucleotide binding]; other site
585397012858	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
585397012859	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
585397012860	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
585397012861	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
585397012862	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
585397012863	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
585397012864	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
585397012865	formate dehydrogenase, alpha subunit, proteobacterial-type; Region: formate-DH-alph; TIGR01553
585397012866	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
585397012867	[4Fe-4S] binding site [ion binding]; other site
585397012868	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
585397012869	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
585397012870	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
585397012871	molybdopterin cofactor binding site; other site
585397012872	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
585397012873	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
585397012874	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
585397012875	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
585397012876	intersubunit interface [polypeptide binding]; other site
585397012877	active site
585397012878	Zn2+ binding site [ion binding]; other site
585397012879	L-rhamnose isomerase; Provisional; Region: PRK01076
585397012880	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
585397012881	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
585397012882	N- and C-terminal domain interface [polypeptide binding]; other site
585397012883	active site
585397012884	putative catalytic site [active]
585397012885	metal binding site [ion binding]; metal-binding site
585397012886	ATP binding site [chemical binding]; other site
585397012887	rhamnulokinase; Provisional; Region: rhaB; PRK10640
585397012888	carbohydrate binding site [chemical binding]; other site
585397012889	transcriptional activator RhaS; Provisional; Region: PRK13503
585397012890	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
585397012891	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397012892	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397012893	transcriptional activator RhaR; Provisional; Region: PRK13500
585397012894	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
585397012895	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397012896	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397012897	L-rhamnose-proton symport protein (RhaT); Region: RhaT; cl05728
585397012898	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
585397012899	superoxide dismutase; Provisional; Region: PRK10925
585397012900	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
585397012901	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
585397012902	2-keto-3-deoxygluconate permease; Region: KdgT; cl14653
585397012903	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
585397012904	MOSC domain; Region: MOSC; pfam03473
585397012905	3-alpha domain; Region: 3-alpha; pfam03475
585397012906	two-component sensor protein; Provisional; Region: cpxA; PRK09470
585397012907	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585397012908	dimerization interface [polypeptide binding]; other site
585397012909	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585397012910	dimer interface [polypeptide binding]; other site
585397012911	phosphorylation site [posttranslational modification]
585397012912	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397012913	ATP binding site [chemical binding]; other site
585397012914	Mg2+ binding site [ion binding]; other site
585397012915	G-X-G motif; other site
585397012916	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
585397012917	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397012918	active site
585397012919	intermolecular recognition site; other site
585397012920	dimerization interface [polypeptide binding]; other site
585397012921	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585397012922	DNA binding site [nucleotide binding]
585397012923	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
585397012924	dimer interface [polypeptide binding]; other site
585397012925	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
585397012926	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
585397012927	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
585397012928	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
585397012929	active site
585397012930	ADP/pyrophosphate binding site [chemical binding]; other site
585397012931	dimerization interface [polypeptide binding]; other site
585397012932	allosteric effector site; other site
585397012933	fructose-1,6-bisphosphate binding site; other site
585397012934	sulfate transporter subunit; Provisional; Region: PRK10752
585397012935	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
585397012936	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
585397012937	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
585397012938	triosephosphate isomerase; Provisional; Region: PRK14567
585397012939	substrate binding site [chemical binding]; other site
585397012940	dimer interface [polypeptide binding]; other site
585397012941	catalytic triad [active]
585397012942	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
585397012943	Predicted membrane protein [Function unknown]; Region: COG3152
585397012944	hypothetical protein; Provisional; Region: PRK09981
585397012945	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
585397012946	Ligand Binding Site [chemical binding]; other site
585397012947	ferredoxin-NADP reductase; Provisional; Region: PRK10926
585397012948	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
585397012949	FAD binding pocket [chemical binding]; other site
585397012950	FAD binding motif [chemical binding]; other site
585397012951	phosphate binding motif [ion binding]; other site
585397012952	beta-alpha-beta structure motif; other site
585397012953	NAD binding pocket [chemical binding]; other site
585397012954	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
585397012955	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
585397012956	putative active site [active]
585397012957	glycerol kinase; Provisional; Region: glpK; PRK00047
585397012958	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
585397012959	N- and C-terminal domain interface [polypeptide binding]; other site
585397012960	active site
585397012961	MgATP binding site [chemical binding]; other site
585397012962	catalytic site [active]
585397012963	metal binding site [ion binding]; metal-binding site
585397012964	glycerol binding site [chemical binding]; other site
585397012965	homotetramer interface [polypeptide binding]; other site
585397012966	homodimer interface [polypeptide binding]; other site
585397012967	FBP binding site [chemical binding]; other site
585397012968	protein IIAGlc interface [polypeptide binding]; other site
585397012969	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
585397012970	amphipathic channel; other site
585397012971	Asn-Pro-Ala signature motifs; other site
585397012972	septal ring assembly protein ZapB; Provisional; Region: PRK15422
585397012973	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
585397012974	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
585397012975	UbiA prenyltransferase family; Region: UbiA; pfam01040
585397012976	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
585397012977	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397012978	Walker A motif; other site
585397012979	ATP binding site [chemical binding]; other site
585397012980	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
585397012981	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
585397012982	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
585397012983	active site
585397012984	HslU subunit interaction site [polypeptide binding]; other site
585397012985	essential cell division protein FtsN; Provisional; Region: PRK10927
585397012986	cell division protein FtsN; Provisional; Region: PRK12757
585397012987	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585397012988	DNA binding site [nucleotide binding]
585397012989	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
585397012990	domain linker motif; other site
585397012991	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
585397012992	dimerization interface [polypeptide binding]; other site
585397012993	ligand binding site [chemical binding]; other site
585397012994	primosome assembly protein PriA; Validated; Region: PRK05580
585397012995	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585397012996	ATP binding site [chemical binding]; other site
585397012997	putative Mg++ binding site [ion binding]; other site
585397012998	helicase superfamily c-terminal domain; Region: HELICc; smart00490
585397012999	ATP-binding site [chemical binding]; other site
585397013000	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
585397013001	hypothetical protein; Provisional; Region: PRK10030
585397013002	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
585397013003	dimerization interface [polypeptide binding]; other site
585397013004	DNA binding site [nucleotide binding]
585397013005	corepressor binding sites; other site
585397013006	cystathionine gamma-synthase; Provisional; Region: PRK08045
585397013007	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
585397013008	homodimer interface [polypeptide binding]; other site
585397013009	substrate-cofactor binding pocket; other site
585397013010	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397013011	catalytic residue [active]
585397013012	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
585397013013	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
585397013014	putative catalytic residues [active]
585397013015	putative nucleotide binding site [chemical binding]; other site
585397013016	putative aspartate binding site [chemical binding]; other site
585397013017	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
585397013018	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
585397013019	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
585397013020	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
585397013021	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
585397013022	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
585397013023	active site
585397013024	metal binding site [ion binding]; metal-binding site
585397013025	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
585397013026	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
585397013027	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
585397013028	active site
585397013029	metal binding site [ion binding]; metal-binding site
585397013030	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
585397013031	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
585397013032	FAD binding site [chemical binding]; other site
585397013033	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
585397013034	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
585397013035	heme binding site [chemical binding]; other site
585397013036	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
585397013037	EamA-like transporter family; Region: EamA; pfam00892
585397013038	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
585397013039	EamA-like transporter family; Region: EamA; pfam00892
585397013040	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
585397013041	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
585397013042	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
585397013043	dimer interface [polypeptide binding]; other site
585397013044	active site
585397013045	metal binding site [ion binding]; metal-binding site
585397013046	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
585397013047	active site
585397013048	intersubunit interactions; other site
585397013049	catalytic residue [active]
585397013050	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
585397013051	dimerization domain swap beta strand [polypeptide binding]; other site
585397013052	regulatory protein interface [polypeptide binding]; other site
585397013053	active site
585397013054	regulatory phosphorylation site [posttranslational modification]; other site
585397013055	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
585397013056	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
585397013057	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
585397013058	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
585397013059	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
585397013060	active site
585397013061	phosphorylation site [posttranslational modification]
585397013062	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
585397013063	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
585397013064	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
585397013065	active site
585397013066	P-loop; other site
585397013067	phosphorylation site [posttranslational modification]
585397013068	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
585397013069	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
585397013070	dimer interface [polypeptide binding]; other site
585397013071	active site
585397013072	glycine loop; other site
585397013073	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
585397013074	FeS/SAM binding site; other site
585397013075	pyruvate formate lyase II activase; Provisional; Region: PRK10076
585397013076	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
585397013077	active site
585397013078	P-loop; other site
585397013079	phosphorylation site [posttranslational modification]
585397013080	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
585397013081	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397013082	hypothetical protein; Provisional; Region: PRK10649
585397013083	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
585397013084	Sulfatase; Region: Sulfatase; pfam00884
585397013085	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
585397013086	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
585397013087	acetylornithine deacetylase; Provisional; Region: PRK05111
585397013088	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
585397013089	metal binding site [ion binding]; metal-binding site
585397013090	putative dimer interface [polypeptide binding]; other site
585397013091	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
585397013092	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
585397013093	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
585397013094	nucleotide binding site [chemical binding]; other site
585397013095	N-acetyl-L-glutamate binding site [chemical binding]; other site
585397013096	argininosuccinate lyase; Provisional; Region: PRK04833
585397013097	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
585397013098	active sites [active]
585397013099	tetramer interface [polypeptide binding]; other site
585397013100	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
585397013101	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
585397013102	putative active site pocket [active]
585397013103	putative metal binding site [ion binding]; other site
585397013104	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397013105	D-galactonate transporter; Region: 2A0114; TIGR00893
585397013106	putative substrate translocation pore; other site
585397013107	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
585397013108	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397013109	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
585397013110	dimerization interface [polypeptide binding]; other site
585397013111	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
585397013112	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585397013113	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
585397013114	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
585397013115	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666
585397013116	metal binding site [ion binding]; metal-binding site
585397013117	putative dimer interface [polypeptide binding]; other site
585397013118	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397013119	metabolite-proton symporter; Region: 2A0106; TIGR00883
585397013120	putative substrate translocation pore; other site
585397013121	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
585397013122	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585397013123	hypothetical protein; Provisional; Region: PRK11056
585397013124	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
585397013125	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397013126	S-adenosylmethionine binding site [chemical binding]; other site
585397013127	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
585397013128	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585397013129	N-terminal plug; other site
585397013130	ligand-binding site [chemical binding]; other site
585397013131	glutamate racemase; Provisional; Region: PRK00865
585397013132	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
585397013133	FAD binding domain; Region: FAD_binding_4; pfam01565
585397013134	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
585397013135	Biotin operon repressor [Transcription]; Region: BirA; COG1654
585397013136	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
585397013137	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
585397013138	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
585397013139	pantothenate kinase; Provisional; Region: PRK05439
585397013140	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
585397013141	ATP-binding site [chemical binding]; other site
585397013142	CoA-binding site [chemical binding]; other site
585397013143	Mg2+-binding site [ion binding]; other site
585397013144	elongation factor Tu; Reviewed; Region: PRK00049
585397013145	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
585397013146	G1 box; other site
585397013147	GEF interaction site [polypeptide binding]; other site
585397013148	GTP/Mg2+ binding site [chemical binding]; other site
585397013149	Switch I region; other site
585397013150	G2 box; other site
585397013151	G3 box; other site
585397013152	Switch II region; other site
585397013153	G4 box; other site
585397013154	G5 box; other site
585397013155	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
585397013156	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
585397013157	Antibiotic Binding Site [chemical binding]; other site
585397013158	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
585397013159	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
585397013160	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
585397013161	putative homodimer interface [polypeptide binding]; other site
585397013162	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
585397013163	heterodimer interface [polypeptide binding]; other site
585397013164	homodimer interface [polypeptide binding]; other site
585397013165	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
585397013166	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
585397013167	23S rRNA interface [nucleotide binding]; other site
585397013168	L7/L12 interface [polypeptide binding]; other site
585397013169	putative thiostrepton binding site; other site
585397013170	L25 interface [polypeptide binding]; other site
585397013171	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
585397013172	mRNA/rRNA interface [nucleotide binding]; other site
585397013173	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
585397013174	23S rRNA interface [nucleotide binding]; other site
585397013175	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
585397013176	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
585397013177	core dimer interface [polypeptide binding]; other site
585397013178	peripheral dimer interface [polypeptide binding]; other site
585397013179	L10 interface [polypeptide binding]; other site
585397013180	L11 interface [polypeptide binding]; other site
585397013181	putative EF-Tu interaction site [polypeptide binding]; other site
585397013182	putative EF-G interaction site [polypeptide binding]; other site
585397013183	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
585397013184	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
585397013185	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
585397013186	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
585397013187	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
585397013188	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
585397013189	RPB3 interaction site [polypeptide binding]; other site
585397013190	RPB1 interaction site [polypeptide binding]; other site
585397013191	RPB11 interaction site [polypeptide binding]; other site
585397013192	RPB10 interaction site [polypeptide binding]; other site
585397013193	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
585397013194	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
585397013195	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
585397013196	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
585397013197	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
585397013198	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
585397013199	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
585397013200	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
585397013201	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
585397013202	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
585397013203	DNA binding site [nucleotide binding]
585397013204	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
585397013205	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
585397013206	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585397013207	FeS/SAM binding site; other site
585397013208	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
585397013209	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
585397013210	ThiS interaction site; other site
585397013211	putative active site [active]
585397013212	tetramer interface [polypeptide binding]; other site
585397013213	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
585397013214	thiS-thiF/thiG interaction site; other site
585397013215	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
585397013216	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
585397013217	ATP binding site [chemical binding]; other site
585397013218	substrate interface [chemical binding]; other site
585397013219	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
585397013220	thiamine phosphate binding site [chemical binding]; other site
585397013221	active site
585397013222	pyrophosphate binding site [ion binding]; other site
585397013223	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
585397013224	ThiC-associated domain; Region: ThiC-associated; pfam13667
585397013225	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
585397013226	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
585397013227	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
585397013228	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
585397013229	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
585397013230	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
585397013231	putative NADH binding site [chemical binding]; other site
585397013232	putative active site [active]
585397013233	nudix motif; other site
585397013234	putative metal binding site [ion binding]; other site
585397013235	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
585397013236	substrate binding site [chemical binding]; other site
585397013237	active site
585397013238	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
585397013239	Active_site [active]
585397013240	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
585397013241	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
585397013242	IHF dimer interface [polypeptide binding]; other site
585397013243	IHF - DNA interface [nucleotide binding]; other site
585397013244	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
585397013245	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
585397013246	dimer interface [polypeptide binding]; other site
585397013247	sensor protein ZraS; Provisional; Region: PRK10364
585397013248	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585397013249	dimer interface [polypeptide binding]; other site
585397013250	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397013251	ATP binding site [chemical binding]; other site
585397013252	Mg2+ binding site [ion binding]; other site
585397013253	G-X-G motif; other site
585397013254	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
585397013255	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397013256	active site
585397013257	phosphorylation site [posttranslational modification]
585397013258	intermolecular recognition site; other site
585397013259	dimerization interface [polypeptide binding]; other site
585397013260	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397013261	Walker A motif; other site
585397013262	ATP binding site [chemical binding]; other site
585397013263	Walker B motif; other site
585397013264	arginine finger; other site
585397013265	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
585397013266	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
585397013267	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
585397013268	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
585397013269	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
585397013270	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
585397013271	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
585397013272	purine monophosphate binding site [chemical binding]; other site
585397013273	dimer interface [polypeptide binding]; other site
585397013274	putative catalytic residues [active]
585397013275	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
585397013276	hypothetical protein; Provisional; Region: PRK10039
585397013277	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
585397013278	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585397013279	Coenzyme A binding pocket [chemical binding]; other site
585397013280	homoserine O-succinyltransferase; Provisional; Region: PRK05368
585397013281	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
585397013282	proposed active site lysine [active]
585397013283	conserved cys residue [active]
585397013284	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
585397013285	malate synthase A; Region: malate_syn_A; TIGR01344
585397013286	active site
585397013287	isocitrate lyase; Provisional; Region: PRK15063
585397013288	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
585397013289	tetramer interface [polypeptide binding]; other site
585397013290	active site
585397013291	Mg2+/Mn2+ binding site [ion binding]; other site
585397013292	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
585397013293	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
585397013294	transcriptional repressor IclR; Provisional; Region: PRK11569
585397013295	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
585397013296	Bacterial transcriptional regulator; Region: IclR; pfam01614
585397013297	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
585397013298	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
585397013299	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
585397013300	substrate binding pocket [chemical binding]; other site
585397013301	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
585397013302	B12 binding site [chemical binding]; other site
585397013303	cobalt ligand [ion binding]; other site
585397013304	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
585397013305	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
585397013306	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
585397013307	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
585397013308	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
585397013309	active site pocket [active]
585397013310	oxyanion hole [active]
585397013311	catalytic triad [active]
585397013312	active site nucleophile [active]
585397013313	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
585397013314	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
585397013315	putative NAD(P) binding site [chemical binding]; other site
585397013316	catalytic Zn binding site [ion binding]; other site
585397013317	PTS system, mannose/fructose/sorbose family, IID component; Region: EIID-AGA; TIGR00828
585397013318	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
585397013319	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
585397013320	active site
585397013321	phosphorylation site [posttranslational modification]
585397013322	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
585397013323	active pocket/dimerization site; other site
585397013324	active site
585397013325	phosphorylation site [posttranslational modification]
585397013326	sorbitol-6-phosphate 2-dehydrogenase; Provisional; Region: PRK06171
585397013327	classical (c) SDRs; Region: SDR_c; cd05233
585397013328	NAD(P) binding site [chemical binding]; other site
585397013329	active site
585397013330	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
585397013331	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
585397013332	putative DNA binding site [nucleotide binding]; other site
585397013333	putative Zn2+ binding site [ion binding]; other site
585397013334	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
585397013335	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
585397013336	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
585397013337	RNA binding surface [nucleotide binding]; other site
585397013338	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
585397013339	probable active site [active]
585397013340	hypothetical protein; Provisional; Region: PRK10515
585397013341	aspartate kinase III; Validated; Region: PRK09084
585397013342	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
585397013343	nucleotide binding site [chemical binding]; other site
585397013344	substrate binding site [chemical binding]; other site
585397013345	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_1; cd04932
585397013346	lysine allosteric regulatory site; other site
585397013347	dimer interface [polypeptide binding]; other site
585397013348	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
585397013349	dimer interface [polypeptide binding]; other site
585397013350	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
585397013351	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
585397013352	active site
585397013353	dimer interface [polypeptide binding]; other site
585397013354	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
585397013355	dimer interface [polypeptide binding]; other site
585397013356	active site
585397013357	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
585397013358	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
585397013359	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
585397013360	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
585397013361	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
585397013362	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
585397013363	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397013364	dimer interface [polypeptide binding]; other site
585397013365	conserved gate region; other site
585397013366	putative PBP binding loops; other site
585397013367	ABC-ATPase subunit interface; other site
585397013368	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397013369	dimer interface [polypeptide binding]; other site
585397013370	conserved gate region; other site
585397013371	putative PBP binding loops; other site
585397013372	ABC-ATPase subunit interface; other site
585397013373	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
585397013374	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
585397013375	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
585397013376	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
585397013377	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
585397013378	Walker A/P-loop; other site
585397013379	ATP binding site [chemical binding]; other site
585397013380	Q-loop/lid; other site
585397013381	ABC transporter signature motif; other site
585397013382	Walker B; other site
585397013383	D-loop; other site
585397013384	H-loop/switch region; other site
585397013385	TOBE domain; Region: TOBE_2; pfam08402
585397013386	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
585397013387	trimer interface; other site
585397013388	sugar binding site [chemical binding]; other site
585397013389	maltose regulon periplasmic protein; Provisional; Region: PRK10564
585397013390	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
585397013391	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
585397013392	UbiA prenyltransferase family; Region: UbiA; pfam01040
585397013393	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
585397013394	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
585397013395	putative acyl-acceptor binding pocket; other site
585397013396	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
585397013397	LexA repressor; Validated; Region: PRK00215
585397013398	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
585397013399	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
585397013400	Catalytic site [active]
585397013401	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
585397013402	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
585397013403	hypothetical protein; Provisional; Region: PRK10428
585397013404	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
585397013405	metal binding site 2 [ion binding]; metal-binding site
585397013406	putative DNA binding helix; other site
585397013407	metal binding site 1 [ion binding]; metal-binding site
585397013408	dimer interface [polypeptide binding]; other site
585397013409	structural Zn2+ binding site [ion binding]; other site
585397013410	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
585397013411	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
585397013412	FMN binding site [chemical binding]; other site
585397013413	active site
585397013414	catalytic residues [active]
585397013415	substrate binding site [chemical binding]; other site
585397013416	phage shock protein G; Reviewed; Region: pspG; PRK09459
585397013417	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
585397013418	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
585397013419	NADP binding site [chemical binding]; other site
585397013420	dimer interface [polypeptide binding]; other site
585397013421	replicative DNA helicase; Provisional; Region: PRK08006
585397013422	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
585397013423	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
585397013424	Walker A motif; other site
585397013425	ATP binding site [chemical binding]; other site
585397013426	Walker B motif; other site
585397013427	DNA binding loops [nucleotide binding]
585397013428	alanine racemase; Reviewed; Region: alr; PRK00053
585397013429	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
585397013430	active site
585397013431	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
585397013432	substrate binding site [chemical binding]; other site
585397013433	catalytic residues [active]
585397013434	dimer interface [polypeptide binding]; other site
585397013435	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
585397013436	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585397013437	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397013438	homodimer interface [polypeptide binding]; other site
585397013439	catalytic residue [active]
585397013440	fragment of 2-oxoglutarate decarboxylase, thiamin-requiring (part 1);Evidence 7 : Gene remnant; Product type e : enzyme
585397013441	fragment of 2-oxoglutarate decarboxylase, thiamin-requiring (part 2);Evidence 7 : Gene remnant; Product type e : enzyme
585397013442	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
585397013443	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
585397013444	E3 interaction surface; other site
585397013445	lipoyl attachment site [posttranslational modification]; other site
585397013446	e3 binding domain; Region: E3_binding; pfam02817
585397013447	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
585397013448	dihydrolipoamide dehydrogenase; Validated; Region: PRK06327
585397013449	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585397013450	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
585397013451	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
585397013452	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
585397013453	CoA-ligase; Region: Ligase_CoA; pfam00549
585397013454	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
585397013455	CoA binding domain; Region: CoA_binding; smart00881
585397013456	CoA-ligase; Region: Ligase_CoA; pfam00549
585397013457	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
585397013458	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
585397013459	transmembrane helices; other site
585397013460	fragment of Putative malate/L-lactate dehydrogenases (part 1);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397013461	fragment of Putative malate/L-lactate dehydrogenases (part 2);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397013462	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
585397013463	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397013464	active site
585397013465	phosphorylation site [posttranslational modification]
585397013466	intermolecular recognition site; other site
585397013467	dimerization interface [polypeptide binding]; other site
585397013468	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397013469	Walker A motif; other site
585397013470	ATP binding site [chemical binding]; other site
585397013471	Walker B motif; other site
585397013472	arginine finger; other site
585397013473	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
585397013474	Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms]; Region: COG4191
585397013475	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585397013476	dimer interface [polypeptide binding]; other site
585397013477	phosphorylation site [posttranslational modification]
585397013478	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397013479	ATP binding site [chemical binding]; other site
585397013480	Mg2+ binding site [ion binding]; other site
585397013481	G-X-G motif; other site
585397013482	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397013483	active site
585397013484	motif I; other site
585397013485	motif II; other site
585397013486	Uncharacterized protein family UPF0047; Region: UPF0047; cl00439
585397013487	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
585397013488	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
585397013489	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
585397013490	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
585397013491	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
585397013492	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
585397013493	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
585397013494	dimer interface [polypeptide binding]; other site
585397013495	ssDNA binding site [nucleotide binding]; other site
585397013496	tetramer (dimer of dimers) interface [polypeptide binding]; other site
585397013497	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
585397013498	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
585397013499	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
585397013500	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585397013501	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
585397013502	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397013503	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
585397013504	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
585397013505	DNA binding residues [nucleotide binding]
585397013506	dimer interface [polypeptide binding]; other site
585397013507	[2Fe-2S] cluster binding site [ion binding]; other site
585397013508	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
585397013509	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
585397013510	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
585397013511	Transcriptional regulator [Transcription]; Region: LysR; COG0583
585397013512	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585397013513	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
585397013514	putative dimerization interface [polypeptide binding]; other site
585397013515	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
585397013516	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
585397013517	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
585397013518	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
585397013519	Na binding site [ion binding]; other site
585397013520	Predicted membrane protein [Function unknown]; Region: COG3162
585397013521	acetyl-CoA synthetase; Provisional; Region: PRK00174
585397013522	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
585397013523	active site
585397013524	CoA binding site [chemical binding]; other site
585397013525	acyl-activating enzyme (AAE) consensus motif; other site
585397013526	AMP binding site [chemical binding]; other site
585397013527	acetate binding site [chemical binding]; other site
585397013528	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
585397013529	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
585397013530	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
585397013531	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
585397013532	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
585397013533	heme lyase subunit NrfE; Provisional; Region: PRK10369
585397013534	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
585397013535	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
585397013536	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585397013537	binding surface
585397013538	TPR motif; other site
585397013539	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
585397013540	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
585397013541	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
585397013542	Sel1-like repeats; Region: SEL1; smart00671
585397013543	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
585397013544	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585397013545	Walker A/P-loop; other site
585397013546	ATP binding site [chemical binding]; other site
585397013547	Q-loop/lid; other site
585397013548	ABC transporter signature motif; other site
585397013549	Walker B; other site
585397013550	D-loop; other site
585397013551	H-loop/switch region; other site
585397013552	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
585397013553	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585397013554	Walker A/P-loop; other site
585397013555	ATP binding site [chemical binding]; other site
585397013556	Q-loop/lid; other site
585397013557	ABC transporter signature motif; other site
585397013558	Walker B; other site
585397013559	D-loop; other site
585397013560	H-loop/switch region; other site
585397013561	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
585397013562	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
585397013563	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397013564	dimer interface [polypeptide binding]; other site
585397013565	conserved gate region; other site
585397013566	ABC-ATPase subunit interface; other site
585397013567	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
585397013568	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397013569	dimer interface [polypeptide binding]; other site
585397013570	conserved gate region; other site
585397013571	putative PBP binding loops; other site
585397013572	ABC-ATPase subunit interface; other site
585397013573	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
585397013574	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
585397013575	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
585397013576	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
585397013577	[4Fe-4S] binding site [ion binding]; other site
585397013578	molybdopterin cofactor binding site; other site
585397013579	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
585397013580	molybdopterin cofactor binding site; other site
585397013581	putative outer membrane efflux protein MdtP; Provisional; Region: PRK09915
585397013582	multidrug efflux system protein MdtO; Provisional; Region: PRK11427
585397013583	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
585397013584	multidrug resistance protein MdtN; Provisional; Region: PRK10476
585397013585	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585397013586	HlyD family secretion protein; Region: HlyD_3; pfam13437
585397013587	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
585397013588	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
585397013589	D-allose kinase; Provisional; Region: PRK09698
585397013590	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
585397013591	nucleotide binding site [chemical binding]; other site
585397013592	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
585397013593	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
585397013594	substrate binding site [chemical binding]; other site
585397013595	hexamer interface [polypeptide binding]; other site
585397013596	metal binding site [ion binding]; metal-binding site
585397013597	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585397013598	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585397013599	TM-ABC transporter signature motif; other site
585397013600	D-allose transporter ATP-binding protein; Provisional; Region: PRK09700
585397013601	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397013602	Walker A/P-loop; other site
585397013603	ATP binding site [chemical binding]; other site
585397013604	Q-loop/lid; other site
585397013605	ABC transporter signature motif; other site
585397013606	Walker B; other site
585397013607	D-loop; other site
585397013608	H-loop/switch region; other site
585397013609	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
585397013610	D-allose transporter subunit; Provisional; Region: PRK09701
585397013611	Periplasmic allose-binding domain of bacterial transport systems that function as a primary receptor of active transport and chemotaxis; Region: PBP1_allose_binding; cd06320
585397013612	ligand binding site [chemical binding]; other site
585397013613	dimerization interface [polypeptide binding]; other site
585397013614	zinc binding site [ion binding]; other site
585397013615	DNA-binding transcriptional repressor RpiR; Provisional; Region: PRK11337
585397013616	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
585397013617	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
585397013618	putative active site [active]
585397013619	Ribose/Galactose Isomerase; Region: LacAB_rpiB; cl00485
585397013620	carbon-phosphorus lyase complex accessory protein; Provisional; Region: phnP; PRK11244
585397013621	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585397013622	Coenzyme A binding pocket [chemical binding]; other site
585397013623	ribose 1,5-bisphosphokinase; Provisional; Region: PRK10078
585397013624	AAA domain; Region: AAA_18; pfam13238
585397013625	active site
585397013626	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
585397013627	Metal-dependent hydrolase involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: COG3454
585397013628	PhnM is believed to be a subunit of the membrane associated C-P lyase complex. C-P lyase is thought to catalyze the direct cleavage of inactivated C-P bonds to yield inorganic phosphate and the corresponding hydrocarbons. It is responsible for cleavage...; Region: PhnM; cd01306
585397013629	active site
585397013630	ABC-type phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PhnL; COG4778
585397013631	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
585397013632	Walker A/P-loop; other site
585397013633	ATP binding site [chemical binding]; other site
585397013634	Q-loop/lid; other site
585397013635	ABC transporter signature motif; other site
585397013636	Walker B; other site
585397013637	D-loop; other site
585397013638	H-loop/switch region; other site
585397013639	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
585397013640	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585397013641	Walker A/P-loop; other site
585397013642	ATP binding site [chemical binding]; other site
585397013643	Q-loop/lid; other site
585397013644	ABC transporter signature motif; other site
585397013645	Walker B; other site
585397013646	D-loop; other site
585397013647	H-loop/switch region; other site
585397013648	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
585397013649	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnJ; COG3627
585397013650	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnI; COG3626
585397013651	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnH; COG3625
585397013652	Phosphonate metabolism protein PhnG; Region: PhnG; pfam06754
585397013653	phosphonate metabolism transcriptional regulator PhnF; Provisional; Region: PRK10079
585397013654	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585397013655	DNA-binding site [nucleotide binding]; DNA binding site
585397013656	UTRA domain; Region: UTRA; pfam07702
585397013657	ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism]; Region: COG3639
585397013658	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397013659	dimer interface [polypeptide binding]; other site
585397013660	conserved gate region; other site
585397013661	putative PBP binding loops; other site
585397013662	ABC-ATPase subunit interface; other site
585397013663	phosphonate ABC transporter, periplasmic phosphonate binding protein; Region: PhnD; TIGR03431
585397013664	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585397013665	substrate binding pocket [chemical binding]; other site
585397013666	membrane-bound complex binding site; other site
585397013667	hinge residues; other site
585397013668	phosphonate/organophosphate ester transporter subunit; Provisional; Region: PRK09984
585397013669	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
585397013670	Walker A/P-loop; other site
585397013671	ATP binding site [chemical binding]; other site
585397013672	Q-loop/lid; other site
585397013673	ABC transporter signature motif; other site
585397013674	Walker B; other site
585397013675	D-loop; other site
585397013676	H-loop/switch region; other site
585397013677	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
585397013678	dimer interface [polypeptide binding]; other site
585397013679	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
585397013680	hypothetical protein; Provisional; Region: PRK10220
585397013681	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
585397013682	PhnA protein; Region: PhnA; pfam03831
585397013683	hypothetical protein; Provisional; Region: PRK09866
585397013684	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
585397013685	G1 box; other site
585397013686	GTP/Mg2+ binding site [chemical binding]; other site
585397013687	G2 box; other site
585397013688	Switch I region; other site
585397013689	G3 box; other site
585397013690	Switch II region; other site
585397013691	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
585397013692	G2 box; other site
585397013693	Switch I region; other site
585397013694	G3 box; other site
585397013695	Switch II region; other site
585397013696	G4 box; other site
585397013697	G5 box; other site
585397013698	YjcZ-like protein; Region: YjcZ; pfam13990
585397013699	proline/glycine betaine transporter; Provisional; Region: PRK10642
585397013700	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397013701	putative substrate translocation pore; other site
585397013702	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
585397013703	sensor protein BasS/PmrB; Provisional; Region: PRK10755
585397013704	HAMP domain; Region: HAMP; pfam00672
585397013705	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585397013706	dimer interface [polypeptide binding]; other site
585397013707	phosphorylation site [posttranslational modification]
585397013708	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397013709	ATP binding site [chemical binding]; other site
585397013710	Mg2+ binding site [ion binding]; other site
585397013711	G-X-G motif; other site
585397013712	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
585397013713	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397013714	active site
585397013715	phosphorylation site [posttranslational modification]
585397013716	intermolecular recognition site; other site
585397013717	dimerization interface [polypeptide binding]; other site
585397013718	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585397013719	DNA binding site [nucleotide binding]
585397013720	putative metal dependent hydrolase; Provisional; Region: PRK11598
585397013721	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
585397013722	Sulfatase; Region: Sulfatase; pfam00884
585397013723	arginine:agmatin antiporter; Provisional; Region: PRK10644
585397013724	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
585397013725	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397013726	arginine decarboxylase; Provisional; Region: PRK15029
585397013727	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
585397013728	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
585397013729	homodimer interface [polypeptide binding]; other site
585397013730	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397013731	catalytic residue [active]
585397013732	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
585397013733	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
585397013734	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397013735	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397013736	alpha-galactosidase; Provisional; Region: PRK15076
585397013737	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
585397013738	NAD binding site [chemical binding]; other site
585397013739	sugar binding site [chemical binding]; other site
585397013740	divalent metal binding site [ion binding]; other site
585397013741	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
585397013742	dimer interface [polypeptide binding]; other site
585397013743	hypothetical protein; Provisional; Region: PRK09867
585397013744	fumarate hydratase; Provisional; Region: PRK15389
585397013745	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
585397013746	Fumarase C-terminus; Region: Fumerase_C; pfam05683
585397013747	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
585397013748	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
585397013749	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
585397013750	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397013751	active site
585397013752	phosphorylation site [posttranslational modification]
585397013753	intermolecular recognition site; other site
585397013754	dimerization interface [polypeptide binding]; other site
585397013755	Transcriptional regulator; Region: CitT; pfam12431
585397013756	sensory histidine kinase DcuS; Provisional; Region: PRK11086
585397013757	PAS domain; Region: PAS; smart00091
585397013758	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397013759	ATP binding site [chemical binding]; other site
585397013760	Mg2+ binding site [ion binding]; other site
585397013761	G-X-G motif; other site
585397013762	Uncharacterized conserved protein [Function unknown]; Region: COG3592
585397013763	Predicted acetyltransferase [General function prediction only]; Region: COG2388
585397013764	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
585397013765	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
585397013766	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
585397013767	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
585397013768	dimer interface [polypeptide binding]; other site
585397013769	putative anticodon binding site; other site
585397013770	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
585397013771	motif 1; other site
585397013772	active site
585397013773	motif 2; other site
585397013774	motif 3; other site
585397013775	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
585397013776	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397013777	putative substrate translocation pore; other site
585397013778	POT family; Region: PTR2; pfam00854
585397013779	lysine decarboxylase CadA; Provisional; Region: PRK15400
585397013780	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
585397013781	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
585397013782	homodimer interface [polypeptide binding]; other site
585397013783	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585397013784	catalytic residue [active]
585397013785	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
585397013786	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
585397013787	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
585397013788	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585397013789	DNA binding site [nucleotide binding]
585397013790	fragment of conserved hypothetical protein (partial);Evidence 7 : Gene remnant
585397013791	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
585397013792	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
585397013793	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
585397013794	Protein of unknown function (DUF987); Region: DUF987; pfam06174
585397013795	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
585397013796	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
585397013797	MPN+ (JAMM) motif; other site
585397013798	Zinc-binding site [ion binding]; other site
585397013799	Antirestriction protein; Region: Antirestrict; pfam03230
585397013800	fragment of putative antirestriction protein (klcA-like) (partial);Evidence 7 : Gene remnant; Product type pf : putative factor
585397013801	Domain of unknown function (DUF932); Region: DUF932; pfam06067
585397013802	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
585397013803	fragment of Conserved hypothetical protein, putative transposase (part 2);Evidence 7 : Gene remnant
585397013804	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
585397013805	Transposase; Region: DDE_Tnp_ISL3; pfam01610
585397013806	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
585397013807	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
585397013808	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
585397013809	putative active site [active]
585397013810	putative NTP binding site [chemical binding]; other site
585397013811	putative nucleic acid binding site [nucleotide binding]; other site
585397013812	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
585397013813	fragment of Conserved hypothetical protein, putative transposase (part 2);Evidence 7 : Gene remnant
585397013814	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
585397013815	Transposase; Region: HTH_Tnp_1; pfam01527
585397013816	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
585397013817	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
585397013818	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
585397013819	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
585397013820	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
585397013821	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
585397013822	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
585397013823	DEXH box helicase, DNA ligase-associated; Region: DEXH_lig_assoc; TIGR04121
585397013824	bifunctional enterobactin receptor/adhesin protein; Provisional; Region: PRK13486
585397013825	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585397013826	N-terminal plug; other site
585397013827	ligand-binding site [chemical binding]; other site
585397013828	fragment of putative homolog to shiA (SHI-2 pathogenicity island of Shigella flexneri) (part 1);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397013829	fragment of putative homolog to shiA (SHI-2 pathogenicity island of Shigella flexneri) (part 2);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397013830	fragment of putative homolog to shiA (SHI-2 pathogenicity island of Shigella flexneri) (part 3);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397013831	bifunctional enterobactin receptor/adhesin protein; Provisional; Region: PRK13486
585397013832	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
585397013833	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585397013834	N-terminal plug; other site
585397013835	ligand-binding site [chemical binding]; other site
585397013836	Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: IucD; COG3486
585397013837	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
585397013838	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
585397013839	IucA / IucC family; Region: IucA_IucC; pfam04183
585397013840	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
585397013841	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
585397013842	Siderophore biosynthesis protein domain; Region: AlcB; smart01006
585397013843	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
585397013844	IucA / IucC family; Region: IucA_IucC; pfam04183
585397013845	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
585397013846	fragment of putative membrane transport protein, major facilitator superfamily (partial);Evidence 7 : Gene remnant; Product type pt : putative transporter
585397013847	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
585397013848	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
585397013849	Transposase; Region: HTH_Tnp_1; pfam01527
585397013850	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
585397013851	N-acetylneuraminate lyase; Provisional; Region: PRK04147
585397013852	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
585397013853	inhibitor site; inhibition site
585397013854	active site
585397013855	dimer interface [polypeptide binding]; other site
585397013856	catalytic residue [active]
585397013857	N-acetylmannosamine kinase; Provisional; Region: PRK05082
585397013858	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
585397013859	nucleotide binding site [chemical binding]; other site
585397013860	putative sialic acid transporter; Provisional; Region: PRK03893
585397013861	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397013862	putative substrate translocation pore; other site
585397013863	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
585397013864	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
585397013865	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
585397013866	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
585397013867	Kelch motif; Region: Kelch_1; pfam01344
585397013868	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
585397013869	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
585397013870	transcriptional regulator NanR; Provisional; Region: PRK03837
585397013871	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585397013872	DNA-binding site [nucleotide binding]; DNA binding site
585397013873	FCD domain; Region: FCD; pfam07729
585397013874	Domain of unknown function (DUF303); Region: DUF303; pfam03629
585397013875	fragment of putative membrane transport protein, major facilitator superfamily (partial);Evidence 7 : Gene remnant; Product type pt : putative transporter
585397013876	fragment of Putative superfamily I DNA helicase (partial);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397013877	integrase; Provisional; Region: PRK09692
585397013878	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
585397013879	active site
585397013880	Int/Topo IB signature motif; other site
585397013881	putative transcriptional regulator; Provisional; Region: PRK11640
585397013882	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585397013883	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
585397013884	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
585397013885	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
585397013886	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
585397013887	DsbD alpha interface [polypeptide binding]; other site
585397013888	catalytic residues [active]
585397013889	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
585397013890	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
585397013891	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
585397013892	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
585397013893	Aspartase; Region: Aspartase; cd01357
585397013894	active sites [active]
585397013895	tetramer interface [polypeptide binding]; other site
585397013896	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
585397013897	putative transporter; Provisional; Region: PRK11021
585397013898	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
585397013899	oligomerisation interface [polypeptide binding]; other site
585397013900	mobile loop; other site
585397013901	roof hairpin; other site
585397013902	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
585397013903	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
585397013904	ring oligomerisation interface [polypeptide binding]; other site
585397013905	ATP/Mg binding site [chemical binding]; other site
585397013906	stacking interactions; other site
585397013907	hinge regions; other site
585397013908	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
585397013909	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
585397013910	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585397013911	FeS/SAM binding site; other site
585397013912	elongation factor P; Validated; Region: PRK00529
585397013913	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
585397013914	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
585397013915	RNA binding site [nucleotide binding]; other site
585397013916	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
585397013917	RNA binding site [nucleotide binding]; other site
585397013918	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
585397013919	multidrug efflux system protein; Provisional; Region: PRK11431
585397013920	Bacterial lipocalin [Cell envelope biogenesis, outer membrane]; Region: Blc; COG3040
585397013921	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
585397013922	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
585397013923	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
585397013924	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
585397013925	Iron-sulfur protein interface; other site
585397013926	proximal quinone binding site [chemical binding]; other site
585397013927	C-subunit interface; other site
585397013928	distal quinone binding site; other site
585397013929	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
585397013930	D-subunit interface [polypeptide binding]; other site
585397013931	Iron-sulfur protein interface; other site
585397013932	proximal quinone binding site [chemical binding]; other site
585397013933	distal quinone binding site [chemical binding]; other site
585397013934	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
585397013935	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
585397013936	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
585397013937	L-aspartate oxidase; Provisional; Region: PRK06175
585397013938	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
585397013939	poxB regulator PoxA; Provisional; Region: PRK09350
585397013940	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
585397013941	motif 1; other site
585397013942	dimer interface [polypeptide binding]; other site
585397013943	active site
585397013944	motif 2; other site
585397013945	motif 3; other site
585397013946	inner membrane transporter YjeM; Provisional; Region: PRK15238
585397013947	putative mechanosensitive channel protein; Provisional; Region: PRK10929
585397013948	linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated...; Region: H15; cl00073
585397013949	DNA-binding site [nucleotide binding]; DNA binding site
585397013950	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
585397013951	Mechanosensitive ion channel; Region: MS_channel; pfam00924
585397013952	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
585397013953	GTPase RsgA; Reviewed; Region: PRK12288
585397013954	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
585397013955	RNA binding site [nucleotide binding]; other site
585397013956	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
585397013957	GTPase/Zn-binding domain interface [polypeptide binding]; other site
585397013958	GTP/Mg2+ binding site [chemical binding]; other site
585397013959	G4 box; other site
585397013960	G5 box; other site
585397013961	G1 box; other site
585397013962	Switch I region; other site
585397013963	G2 box; other site
585397013964	G3 box; other site
585397013965	Switch II region; other site
585397013966	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
585397013967	catalytic site [active]
585397013968	putative active site [active]
585397013969	putative substrate binding site [chemical binding]; other site
585397013970	dimer interface [polypeptide binding]; other site
585397013971	epoxyqueuosine reductase; Region: TIGR00276
585397013972	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
585397013973	putative carbohydrate kinase; Provisional; Region: PRK10565
585397013974	yjeF N-terminal region; Region: yjeF_nterm; TIGR00197
585397013975	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
585397013976	putative substrate binding site [chemical binding]; other site
585397013977	putative ATP binding site [chemical binding]; other site
585397013978	ADP-binding protein; Provisional; Region: PRK10646
585397013979	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
585397013980	AMIN domain; Region: AMIN; pfam11741
585397013981	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
585397013982	active site
585397013983	metal binding site [ion binding]; metal-binding site
585397013984	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
585397013985	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397013986	ATP binding site [chemical binding]; other site
585397013987	Mg2+ binding site [ion binding]; other site
585397013988	G-X-G motif; other site
585397013989	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
585397013990	ATP binding site [chemical binding]; other site
585397013991	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
585397013992	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
585397013993	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
585397013994	bacterial Hfq-like; Region: Hfq; cd01716
585397013995	hexamer interface [polypeptide binding]; other site
585397013996	Sm1 motif; other site
585397013997	RNA binding site [nucleotide binding]; other site
585397013998	Sm2 motif; other site
585397013999	GTPase HflX; Provisional; Region: PRK11058
585397014000	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
585397014001	HflX GTPase family; Region: HflX; cd01878
585397014002	G1 box; other site
585397014003	GTP/Mg2+ binding site [chemical binding]; other site
585397014004	Switch I region; other site
585397014005	G2 box; other site
585397014006	G3 box; other site
585397014007	Switch II region; other site
585397014008	G4 box; other site
585397014009	G5 box; other site
585397014010	FtsH protease regulator HflK; Provisional; Region: PRK10930
585397014011	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
585397014012	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
585397014013	FtsH protease regulator HflC; Provisional; Region: PRK11029
585397014014	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
585397014015	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
585397014016	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
585397014017	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
585397014018	GDP-binding site [chemical binding]; other site
585397014019	ACT binding site; other site
585397014020	IMP binding site; other site
585397014021	Predicted transcriptional regulator [Transcription]; Region: COG1959
585397014022	transcriptional repressor NsrR; Provisional; Region: PRK11014
585397014023	exoribonuclease R; Provisional; Region: PRK11642
585397014024	Ribonuclease R winged-helix domain; Region: HTH_12; pfam08461
585397014025	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
585397014026	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
585397014027	RNB domain; Region: RNB; pfam00773
585397014028	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
585397014029	RNA binding site [nucleotide binding]; other site
585397014030	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
585397014031	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
585397014032	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
585397014033	Uncharacterized protein conserved in bacteria (DUF2170); Region: DUF2170; cl01551
585397014034	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
585397014035	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
585397014036	Predicted membrane protein [Function unknown]; Region: COG3766
585397014037	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
585397014038	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
585397014039	Predicted integral membrane protein [Function unknown]; Region: COG5463
585397014040	fragment of putative synthetase/amidase (part 1);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397014041	fragment of putative synthetase/amidase (part 2);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397014042	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
585397014043	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
585397014044	FAD binding site [chemical binding]; other site
585397014045	substrate binding site [chemical binding]; other site
585397014046	catalytic residues [active]
585397014047	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
585397014048	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
585397014049	esterase; Provisional; Region: PRK10566
585397014050	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
585397014051	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
585397014052	transcriptional repressor UlaR; Provisional; Region: PRK13509
585397014053	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
585397014054	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585397014055	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
585397014056	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
585397014057	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
585397014058	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
585397014059	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
585397014060	active site
585397014061	P-loop; other site
585397014062	phosphorylation site [posttranslational modification]
585397014063	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
585397014064	active site
585397014065	phosphorylation site [posttranslational modification]
585397014066	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
585397014067	active site
585397014068	dimer interface [polypeptide binding]; other site
585397014069	magnesium binding site [ion binding]; other site
585397014070	Methyltransferase domain; Region: Methyltransf_27; pfam13708
585397014071	fragment of conserved hypothetical protein (partial);Evidence 7 : Gene remnant
585397014072	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
585397014073	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
585397014074	Protein of unknown function (DUF987); Region: DUF987; pfam06174
585397014075	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
585397014076	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
585397014077	MPN+ (JAMM) motif; other site
585397014078	Zinc-binding site [ion binding]; other site
585397014079	Antirestriction protein; Region: Antirestrict; pfam03230
585397014080	fragment of putative antirestriction protein (klcA-like) (partial);Evidence 7 : Gene remnant; Product type pf : putative factor
585397014081	Domain of unknown function (DUF932); Region: DUF932; pfam06067
585397014082	fragment of conserved hypothetical protein similar to Aec70 (partial);Evidence 7 : Gene remnant
585397014083	fragment of conserved hypothetical protein; putative membrane protein, yeeR (partial);Evidence 7 : Gene remnant; Product type pm : putative membrane component
585397014084	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
585397014085	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
585397014086	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
585397014087	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
585397014088	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
585397014089	putative active site cavity [active]
585397014090	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
585397014091	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
585397014092	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
585397014093	active site turn [active]
585397014094	phosphorylation site [posttranslational modification]
585397014095	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
585397014096	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
585397014097	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
585397014098	putative active site [active]
585397014099	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397014100	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397014101	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397014102	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397014103	fragment of regulator of length of O-antigen component of lipopolysaccharide chains (part 1);Evidence 7 : Gene remnant; Product type r : regulator
585397014104	fragment of regulator of length of O-antigen component of lipopolysaccharide chains (part 2);Evidence 7 : Gene remnant; Product type r : regulator
585397014105	Transposase; Region: HTH_Tnp_1; pfam01527
585397014106	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
585397014107	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
585397014108	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
585397014109	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
585397014110	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
585397014111	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
585397014112	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
585397014113	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
585397014114	fragment of regulator of length of O-antigen component of lipopolysaccharide chains (part 3);Evidence 7 : Gene remnant; Product type r : regulator
585397014115	putative transposase (fragment);Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme
585397014116	putative transposase OrfB; Reviewed; Region: PHA02517
585397014117	HTH-like domain; Region: HTH_21; pfam13276
585397014118	Integrase core domain; Region: rve; pfam00665
585397014119	Integrase core domain; Region: rve_3; pfam13683
585397014120	Transposase; Region: HTH_Tnp_1; cl17663
585397014121	Uncharacterized conserved protein [Function unknown]; Region: COG1556
585397014122	iron-sulfur cluster-binding protein; Region: TIGR00273
585397014123	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
585397014124	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
585397014125	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
585397014126	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
585397014127	Cysteine-rich domain; Region: CCG; pfam02754
585397014128	Cysteine-rich domain; Region: CCG; pfam02754
585397014129	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
585397014130	L-lactate permease; Region: Lactate_perm; cl00701
585397014131	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
585397014132	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397014133	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397014134	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397014135	transposase ORF 2, IS1 (part 1);Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
585397014136	transposase ORF 2, IS1 (part 2);Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
585397014137	fragment of conserved hypothetical protein, putative transposase ORF1, IS66 family (partial);Evidence 7 : Gene remnant
585397014138	fragment of transposase, IS110 family (partial);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397014139	Transposase; Region: DEDD_Tnp_IS110; pfam01548
585397014140	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
585397014141	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
585397014142	DEXH box helicase, DNA ligase-associated; Region: DEXH_lig_assoc; TIGR04121
585397014143	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585397014144	ferric transporter ATP-binding subunit; Provisional; Region: fbpC; PRK11432
585397014145	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397014146	Walker A/P-loop; other site
585397014147	ATP binding site [chemical binding]; other site
585397014148	Q-loop/lid; other site
585397014149	ABC transporter signature motif; other site
585397014150	Walker B; other site
585397014151	D-loop; other site
585397014152	H-loop/switch region; other site
585397014153	TOBE domain; Region: TOBE_2; pfam08402
585397014154	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
585397014155	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397014156	dimer interface [polypeptide binding]; other site
585397014157	conserved gate region; other site
585397014158	putative PBP binding loops; other site
585397014159	ABC-ATPase subunit interface; other site
585397014160	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585397014161	dimer interface [polypeptide binding]; other site
585397014162	conserved gate region; other site
585397014163	putative PBP binding loops; other site
585397014164	ABC-ATPase subunit interface; other site
585397014165	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
585397014166	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
585397014167	regulatory protein UhpC; Provisional; Region: PRK11663
585397014168	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397014169	putative substrate translocation pore; other site
585397014170	Signal transduction histidine kinase, glucose-6-phosphate specific [Signal transduction mechanisms]; Region: UhpB; COG3851
585397014171	MASE1; Region: MASE1; pfam05231
585397014172	Histidine kinase; Region: HisKA_3; pfam07730
585397014173	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397014174	ATP binding site [chemical binding]; other site
585397014175	Mg2+ binding site [ion binding]; other site
585397014176	G-X-G motif; other site
585397014177	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
585397014178	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397014179	active site
585397014180	phosphorylation site [posttranslational modification]
585397014181	intermolecular recognition site; other site
585397014182	dimerization interface [polypeptide binding]; other site
585397014183	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585397014184	DNA binding residues [nucleotide binding]
585397014185	dimerization interface [polypeptide binding]; other site
585397014186	integrase; Provisional; Region: PRK09692
585397014187	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
585397014188	active site
585397014189	Int/Topo IB signature motif; other site
585397014190	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
585397014191	AP (apurinic/apyrimidinic) site pocket; other site
585397014192	DNA interaction; other site
585397014193	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
585397014194	Metal-binding active site; metal-binding site
585397014195	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
585397014196	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
585397014197	intersubunit interface [polypeptide binding]; other site
585397014198	active site
585397014199	Zn2+ binding site [ion binding]; other site
585397014200	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
585397014201	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
585397014202	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
585397014203	dimer interface [polypeptide binding]; other site
585397014204	ssDNA binding site [nucleotide binding]; other site
585397014205	tetramer (dimer of dimers) interface [polypeptide binding]; other site
585397014206	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
585397014207	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
585397014208	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
585397014209	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
585397014210	Helix-turn-helix domain; Region: HTH_31; pfam13560
585397014211	sequence-specific DNA binding site [nucleotide binding]; other site
585397014212	salt bridge; other site
585397014213	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
585397014214	HipA-like N-terminal domain; Region: HipA_N; pfam07805
585397014215	HipA-like C-terminal domain; Region: HipA_C; pfam07804
585397014216	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585397014217	D-galactonate transporter; Region: 2A0114; TIGR00893
585397014218	putative substrate translocation pore; other site
585397014219	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Region: SdhA; COG1053
585397014220	L-aspartate oxidase; Provisional; Region: PRK06175
585397014221	L-aspartate oxidase; Provisional; Region: PRK06175
585397014222	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
585397014223	Coenzyme A transferase; Region: CoA_trans; smart00882
585397014224	Coenzyme A transferase; Region: CoA_trans; cl17247
585397014225	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
585397014226	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
585397014227	substrate binding site [chemical binding]; other site
585397014228	oxyanion hole (OAH) forming residues; other site
585397014229	trimer interface [polypeptide binding]; other site
585397014230	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
585397014231	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: PRK12745
585397014232	putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR), subgroup 1, classical (c) SDR; Region: BKR_1_SDR_c; cd05337
585397014233	putative NAD(P) binding site [chemical binding]; other site
585397014234	active site
585397014235	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
585397014236	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585397014237	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
585397014238	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
585397014239	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
585397014240	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
585397014241	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
585397014242	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
585397014243	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
585397014244	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
585397014245	Hemerythrin-like domain; Region: Hr-like; cd12108
585397014246	Fe binding site [ion binding]; other site
585397014247	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
585397014248	EamA-like transporter family; Region: EamA; pfam00892
585397014249	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
585397014250	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
585397014251	NADP binding site [chemical binding]; other site
585397014252	Predicted transcriptional regulators [Transcription]; Region: COG1733
585397014253	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
585397014254	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
585397014255	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
585397014256	active site
585397014257	metal binding site [ion binding]; metal-binding site
585397014258	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
585397014259	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
585397014260	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
585397014261	active site
585397014262	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
585397014263	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
585397014264	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
585397014265	Domain of unknown function DUF21; Region: DUF21; pfam01595
585397014266	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
585397014267	Transporter associated domain; Region: CorC_HlyC; smart01091
585397014268	methionine sulfoxide reductase A; Provisional; Region: PRK00058
585397014269	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
585397014270	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
585397014271	Surface antigen; Region: Bac_surface_Ag; pfam01103
585397014272	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
585397014273	Family of unknown function (DUF490); Region: DUF490; pfam04357
585397014274	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
585397014275	putative active site pocket [active]
585397014276	dimerization interface [polypeptide binding]; other site
585397014277	putative catalytic residue [active]
585397014278	Sel1-like repeats; Region: SEL1; smart00671
585397014279	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
585397014280	Sel1-like repeats; Region: SEL1; smart00671
585397014281	Sel1-like repeats; Region: SEL1; smart00671
585397014282	Sel1-like repeats; Region: SEL1; smart00671
585397014283	Sel1-like repeats; Region: SEL1; smart00671
585397014284	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
585397014285	Sel1-like repeats; Region: SEL1; smart00671
585397014286	Sel1-like repeats; Region: SEL1; smart00671
585397014287	Sel1-like repeats; Region: SEL1; smart00671
585397014288	Sel1-like repeats; Region: SEL1; smart00671
585397014289	Sel1-like repeats; Region: SEL1; smart00671
585397014290	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
585397014291	dimer interface [polypeptide binding]; other site
585397014292	substrate binding site [chemical binding]; other site
585397014293	metal binding sites [ion binding]; metal-binding site
585397014294	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
585397014295	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
585397014296	putative ligand binding site [chemical binding]; other site
585397014297	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
585397014298	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
585397014299	Walker A/P-loop; other site
585397014300	ATP binding site [chemical binding]; other site
585397014301	Q-loop/lid; other site
585397014302	ABC transporter signature motif; other site
585397014303	Walker B; other site
585397014304	D-loop; other site
585397014305	H-loop/switch region; other site
585397014306	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
585397014307	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585397014308	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585397014309	TM-ABC transporter signature motif; other site
585397014310	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585397014311	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585397014312	TM-ABC transporter signature motif; other site
585397014313	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
585397014314	AMP binding site [chemical binding]; other site
585397014315	metal binding site [ion binding]; metal-binding site
585397014316	active site
585397014317	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
585397014318	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
585397014319	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
585397014320	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
585397014321	hypothetical protein; Provisional; Region: PRK05255
585397014322	peptidase PmbA; Provisional; Region: PRK11040
585397014323	cytochrome b562; Provisional; Region: PRK15058
585397014324	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
585397014325	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585397014326	FeS/SAM binding site; other site
585397014327	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
585397014328	ATP cone domain; Region: ATP-cone; pfam03477
585397014329	Class III ribonucleotide reductase; Region: RNR_III; cd01675
585397014330	effector binding site; other site
585397014331	active site
585397014332	Zn binding site [ion binding]; other site
585397014333	glycine loop; other site
585397014334	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
585397014335	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
585397014336	Ca binding site [ion binding]; other site
585397014337	active site
585397014338	catalytic site [active]
585397014339	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
585397014340	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
585397014341	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
585397014342	active site turn [active]
585397014343	phosphorylation site [posttranslational modification]
585397014344	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
585397014345	trehalose repressor; Provisional; Region: treR; PRK09492
585397014346	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585397014347	DNA binding site [nucleotide binding]
585397014348	domain linker motif; other site
585397014349	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
585397014350	dimerization interface [polypeptide binding]; other site
585397014351	ligand binding site [chemical binding]; other site
585397014352	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
585397014353	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
585397014354	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
585397014355	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
585397014356	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397014357	motif II; other site
585397014358	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
585397014359	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
585397014360	homotrimer interaction site [polypeptide binding]; other site
585397014361	putative active site [active]
585397014362	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
585397014363	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
585397014364	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
585397014365	aspartate carbamoyltransferase; Region: asp_carb_tr; TIGR00670
585397014366	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
585397014367	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
585397014368	PyrBI operon leader peptide; Region: PyrBI_leader; pfam08052
585397014369	Arginine repressor [Transcription]; Region: ArgR; COG1438
585397014370	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
585397014371	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
585397014372	Predicted membrane protein [Function unknown]; Region: COG1288
585397014373	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
585397014374	ornithine carbamoyltransferase; Validated; Region: PRK02102
585397014375	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
585397014376	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
585397014377	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
585397014378	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
585397014379	putative substrate binding site [chemical binding]; other site
585397014380	nucleotide binding site [chemical binding]; other site
585397014381	nucleotide binding site [chemical binding]; other site
585397014382	homodimer interface [polypeptide binding]; other site
585397014383	arginine deiminase; Provisional; Region: PRK01388
585397014384	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
585397014385	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
585397014386	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
585397014387	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
585397014388	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
585397014389	RNase E inhibitor protein; Provisional; Region: PRK11191
585397014390	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
585397014391	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585397014392	Coenzyme A binding pocket [chemical binding]; other site
585397014393	Bacterial protein of unknown function (DUF898); Region: DUF898; cl01738
585397014394	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
585397014395	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
585397014396	HIGH motif; other site
585397014397	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
585397014398	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
585397014399	active site
585397014400	KMSKS motif; other site
585397014401	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
585397014402	tRNA binding surface [nucleotide binding]; other site
585397014403	anticodon binding site; other site
585397014404	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
585397014405	DNA polymerase III subunit chi; Validated; Region: PRK05728
585397014406	multifunctional aminopeptidase A; Provisional; Region: PRK00913
585397014407	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
585397014408	interface (dimer of trimers) [polypeptide binding]; other site
585397014409	Substrate-binding/catalytic site; other site
585397014410	Zn-binding sites [ion binding]; other site
585397014411	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
585397014412	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
585397014413	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
585397014414	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
585397014415	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
585397014416	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
585397014417	Walker A motif; other site
585397014418	ATP binding site [chemical binding]; other site
585397014419	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
585397014420	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585397014421	DNA binding site [nucleotide binding]
585397014422	domain linker motif; other site
585397014423	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
585397014424	putative dimerization interface [polypeptide binding]; other site
585397014425	putative ligand binding site [chemical binding]; other site
585397014426	fragment of L-idonate and D-gluconate transporter (part 2);Evidence 7 : Gene remnant; Product type t : transporter
585397014427	fragment of L-idonate and D-gluconate transporter (part 1);Evidence 7 : Gene remnant; Product type t : transporter
585397014428	gluconate 5-dehydrogenase; Provisional; Region: PRK08085
585397014429	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
585397014430	NADP binding site [chemical binding]; other site
585397014431	homodimer interface [polypeptide binding]; other site
585397014432	active site
585397014433	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
585397014434	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
585397014435	putative NAD(P) binding site [chemical binding]; other site
585397014436	catalytic Zn binding site [ion binding]; other site
585397014437	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
585397014438	ATP-binding site [chemical binding]; other site
585397014439	Gluconate-6-phosphate binding site [chemical binding]; other site
585397014440	Shikimate kinase; Region: SKI; pfam01202
585397014441	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
585397014442	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
585397014443	putative NAD(P) binding site [chemical binding]; other site
585397014444	putative substrate binding site [chemical binding]; other site
585397014445	catalytic Zn binding site [ion binding]; other site
585397014446	structural Zn binding site [ion binding]; other site
585397014447	dimer interface [polypeptide binding]; other site
585397014448	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
585397014449	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
585397014450	active site
585397014451	Int/Topo IB signature motif; other site
585397014452	fragment of conserved hypothetical protein (partial);Evidence 7 : Gene remnant
585397014453	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
585397014454	Transposase domain (DUF772); Region: DUF772; pfam05598
585397014455	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
585397014456	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
585397014457	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
585397014458	Integrase core domain; Region: rve; pfam00665
585397014459	transposase ORF B, IS100 (part1);Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
585397014460	transposase ORF B, IS100 (part 2);Evidence 2b : Function of strongly homologous gene; Product type e : enzyme
585397014461	mycofactocin system transcriptional regulator; Region: mycofact_TetR; TIGR03968
585397014462	Predicted membrane protein [Function unknown]; Region: COG4325
585397014463	Predicted membrane protein (DUF2254); Region: DUF2254; pfam10011
585397014464	BCCT family transporter; Region: BCCT; cl00569
585397014465	putative transposase OrfB; Reviewed; Region: PHA02517
585397014466	Integrase core domain; Region: rve; pfam00665
585397014467	Integrase core domain; Region: rve_3; pfam13683
585397014468	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
585397014469	Transposase; Region: HTH_Tnp_1; pfam01527
585397014470	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
585397014471	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
585397014472	putative acyl-acceptor binding pocket; other site
585397014473	Protein of unknown function (DUF535); Region: DUF535; pfam04393
585397014474	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
585397014475	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
585397014476	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
585397014477	putative active site [active]
585397014478	putative metal binding site [ion binding]; other site
585397014479	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
585397014480	Transposase; Region: HTH_Tnp_1; cl17663
585397014481	fragment of transposase ORF B (fragment), IS911 (part 1);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397014482	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
585397014483	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
585397014484	putative active site [active]
585397014485	putative NTP binding site [chemical binding]; other site
585397014486	putative nucleic acid binding site [nucleotide binding]; other site
585397014487	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
585397014488	fragment of transposase ORF B (fragment), IS911 (part 2);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397014489	fragment of transposase ORF B, IS911 (partial);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397014490	Predicted dinucleotide-binding enzymes [General function prediction only]; Region: COG2085
585397014491	iron-dicitrate transporter ATP-binding subunit; Provisional; Region: fecE; PRK11231
585397014492	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
585397014493	Walker A/P-loop; other site
585397014494	ATP binding site [chemical binding]; other site
585397014495	Q-loop/lid; other site
585397014496	ABC transporter signature motif; other site
585397014497	Walker B; other site
585397014498	D-loop; other site
585397014499	H-loop/switch region; other site
585397014500	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
585397014501	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
585397014502	ABC-ATPase subunit  interface; other site
585397014503	dimer interface [polypeptide binding]; other site
585397014504	putative PBP binding regions; other site
585397014505	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
585397014506	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
585397014507	dimer interface [polypeptide binding]; other site
585397014508	ABC-ATPase subunit  interface; other site
585397014509	putative PBP binding regions; other site
585397014510	iron-dicitrate transporter substrate-binding subunit; Provisional; Region: fecB; PRK11411
585397014511	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
585397014512	siderophore binding site; other site
585397014513	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
585397014514	Secretin and TonB N terminus short domain; Region: STN; smart00965
585397014515	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585397014516	N-terminal plug; other site
585397014517	ligand-binding site [chemical binding]; other site
585397014518	fec operon regulator FecR; Reviewed; Region: PRK09774
585397014519	FecR protein; Region: FecR; pfam04773
585397014520	RNA polymerase sigma factor FecI; Provisional; Region: PRK09651
585397014521	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
585397014522	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
585397014523	DNA binding residues [nucleotide binding]
585397014524	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397014525	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397014526	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397014527	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397014528	Esterase-like activity of phytase; Region: Phytase-like; pfam13449
585397014529	fragment of putative transposase ORF 1, IS66 family (part 2);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397014530	fragment of putative transposase ORF 1, IS66 family (part 1);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585397014531	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
585397014532	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
585397014533	Transposase; Region: HTH_Tnp_1; pfam01527
585397014534	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
585397014535	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
585397014536	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
585397014537	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
585397014538	Haemolysin expression modulating protein; Region: HHA; pfam05321
585397014539	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; pfam05930
585397014540	Replication regulatory protein RepB; Region: RepB-RCR_reg; cl11673
585397014541	Predicted GTPase [General function prediction only]; Region: COG3596
585397014542	YfjP GTPase; Region: YfjP; cd11383
585397014543	G1 box; other site
585397014544	GTP/Mg2+ binding site [chemical binding]; other site
585397014545	Switch I region; other site
585397014546	G2 box; other site
585397014547	Switch II region; other site
585397014548	G3 box; other site
585397014549	G4 box; other site
585397014550	G5 box; other site
585397014551	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
585397014552	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
585397014553	hypothetical protein; Provisional; Region: PRK09945
585397014554	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
585397014555	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
585397014556	Autotransporter beta-domain; Region: Autotransporter; smart00869
585397014557	fragment of conserved hypothetical protein similar to Aec70 (partial);Evidence 7 : Gene remnant
585397014558	Domain of unknown function (DUF932); Region: DUF932; pfam06067
585397014559	Antirestriction protein; Region: Antirestrict; pfam03230
585397014560	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
585397014561	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
585397014562	MPN+ (JAMM) motif; other site
585397014563	Zinc-binding site [ion binding]; other site
585397014564	Protein of unknown function (DUF987); Region: DUF987; pfam06174
585397014565	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
585397014566	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
585397014567	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
585397014568	Type III restriction-modification system EcoPI enzyme res (fragment N-ter);Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2837577, 8387444, 1587478; Product type h : extrachromosomal origin
585397014569	Domain of unknown function (DUF303); Region: DUF303; pfam03629
585397014570	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
585397014571	Kelch motif; Region: Kelch_1; pfam01344
585397014572	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
585397014573	FimB and FimE and related proteins, DNA breaking-rejoining enzymes, integrase/recombinases, catalytic domain. This CD includes those proteins similar to E.coli FimE and FimB regulatory proteins and Proteus mirabilis MrpI; Region: INT_FimBE_C; cd01197
585397014574	Int/Topo IB signature motif; other site
585397014575	FimB and FimE and related proteins, DNA breaking-rejoining enzymes, integrase/recombinases, catalytic domain. This CD includes those proteins similar to E.coli FimE and FimB regulatory proteins and Proteus mirabilis MrpI; Region: INT_FimBE_C; cd01197
585397014576	Int/Topo IB signature motif; other site
585397014577	Fimbrial protein; Region: Fimbrial; cl01416
585397014578	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
585397014579	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
585397014580	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585397014581	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
585397014582	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
585397014583	PapC N-terminal domain; Region: PapC_N; pfam13954
585397014584	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585397014585	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
585397014586	mannosyl binding site [chemical binding]; other site
585397014587	Fimbrial protein; Region: Fimbrial; pfam00419
585397014588	fragment of fructuronate transporter (partial);Evidence 7 : Gene remnant; Product type t : transporter
585397014589	mannonate dehydratase; Region: uxuA; TIGR00695
585397014590	mannonate dehydratase; Provisional; Region: PRK03906
585397014591	D-mannonate oxidoreductase; Provisional; Region: PRK15037
585397014592	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
585397014593	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
585397014594	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
585397014595	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585397014596	DNA-binding site [nucleotide binding]; DNA binding site
585397014597	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
585397014598	Predicted membrane protein [Function unknown]; Region: COG2733
585397014599	putative transposase; Provisional; Region: PRK09857
585397014600	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
585397014601	Uncharacterized conserved protein [Function unknown]; Region: COG1479
585397014602	Protein of unknown function DUF262; Region: DUF262; pfam03235
585397014603	Protein of unknown function DUF262; Region: DUF262; pfam03235
585397014604	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
585397014605	Uncharacterized conserved protein [Function unknown]; Region: COG3586
585397014606	endoribonuclease SymE; Provisional; Region: PRK13605
585397014607	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
585397014608	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
585397014609	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
585397014610	HsdM N-terminal domain; Region: HsdM_N; pfam12161
585397014611	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
585397014612	Methyltransferase domain; Region: Methyltransf_26; pfam13659
585397014613	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: HsdR; COG4096
585397014614	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
585397014615	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585397014616	ATP binding site [chemical binding]; other site
585397014617	putative Mg++ binding site [ion binding]; other site
585397014618	fragment of conserved hypothetical protein (partial);Evidence 7 : Gene remnant
585397014619	Uncharacterized conserved protein [Function unknown]; Region: COG1479
585397014620	Protein of unknown function DUF262; Region: DUF262; pfam03235
585397014621	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
585397014622	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
585397014623	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
585397014624	P-loop, Walker A motif; other site
585397014625	Base recognition motif; other site
585397014626	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
585397014627	Uncharacterized small protein [Function unknown]; Region: COG2879
585397014628	carbon starvation protein A; Provisional; Region: PRK15015
585397014629	Carbon starvation protein CstA; Region: CstA; pfam02554
585397014630	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
585397014631	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
585397014632	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
585397014633	dimer interface [polypeptide binding]; other site
585397014634	ligand binding site [chemical binding]; other site
585397014635	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585397014636	dimerization interface [polypeptide binding]; other site
585397014637	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
585397014638	dimer interface [polypeptide binding]; other site
585397014639	putative CheW interface [polypeptide binding]; other site
585397014640	DctM-like transporters; Region: DctM; pfam06808
585397014641	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
585397014642	Tripartite ATP-independent periplasmic transporters, DctQ component; Region: DctQ; pfam04290
585397014643	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
585397014644	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; cl15441
585397014645	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
585397014646	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
585397014647	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585397014648	DNA-binding site [nucleotide binding]; DNA binding site
585397014649	Transcriptional regulators [Transcription]; Region: GntR; COG1802
585397014650	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
585397014651	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
585397014652	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
585397014653	putative NAD(P) binding site [chemical binding]; other site
585397014654	catalytic Zn binding site [ion binding]; other site
585397014655	structural Zn binding site [ion binding]; other site
585397014656	phosphoglycerol transferase I; Provisional; Region: PRK03776
585397014657	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
585397014658	hypothetical protein; Provisional; Region: PRK11667
585397014659	DNA replication protein DnaC; Validated; Region: PRK07952
585397014660	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585397014661	Walker A motif; other site
585397014662	ATP binding site [chemical binding]; other site
585397014663	Walker B motif; other site
585397014664	primosomal protein DnaI; Provisional; Region: PRK02854
585397014665	hypothetical protein; Provisional; Region: PRK09917
585397014666	Uncharacterized conserved protein [Function unknown]; Region: COG2966
585397014667	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
585397014668	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
585397014669	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
585397014670	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
585397014671	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
585397014672	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
585397014673	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585397014674	DNA binding residues [nucleotide binding]
585397014675	dimerization interface [polypeptide binding]; other site
585397014676	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
585397014677	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585397014678	DNA binding residues [nucleotide binding]
585397014679	dimerization interface [polypeptide binding]; other site
585397014680	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
585397014681	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
585397014682	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
585397014683	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
585397014684	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
585397014685	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
585397014686	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585397014687	S-adenosylmethionine binding site [chemical binding]; other site
585397014688	DNA polymerase III subunit psi; Validated; Region: PRK06856
585397014689	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
585397014690	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585397014691	Coenzyme A binding pocket [chemical binding]; other site
585397014692	dUMP phosphatase; Provisional; Region: PRK09449
585397014693	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397014694	motif II; other site
585397014695	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
585397014696	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
585397014697	G1 box; other site
585397014698	putative GEF interaction site [polypeptide binding]; other site
585397014699	GTP/Mg2+ binding site [chemical binding]; other site
585397014700	Switch I region; other site
585397014701	G2 box; other site
585397014702	G3 box; other site
585397014703	Switch II region; other site
585397014704	G4 box; other site
585397014705	G5 box; other site
585397014706	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
585397014707	periplasmic protein; Provisional; Region: PRK10568
585397014708	BON domain; Region: BON; pfam04972
585397014709	BON domain; Region: BON; pfam04972
585397014710	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
585397014711	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
585397014712	active site
585397014713	nucleophile elbow; other site
585397014714	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
585397014715	active site
585397014716	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
585397014717	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585397014718	FeS/SAM binding site; other site
585397014719	hypothetical protein; Provisional; Region: PRK10977
585397014720	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
585397014721	intersubunit interface [polypeptide binding]; other site
585397014722	active site
585397014723	catalytic residue [active]
585397014724	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
585397014725	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
585397014726	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
585397014727	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
585397014728	phosphopentomutase; Provisional; Region: PRK05362
585397014729	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
585397014730	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
585397014731	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
585397014732	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09775
585397014733	HipA-like N-terminal domain; Region: HipA_N; pfam07805
585397014734	HipA-like C-terminal domain; Region: HipA_C; pfam07804
585397014735	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
585397014736	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
585397014737	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
585397014738	hypothetical protein; Provisional; Region: PRK11246
585397014739	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
585397014740	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585397014741	motif II; other site
585397014742	DNA repair protein RadA; Region: sms; TIGR00416
585397014743	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
585397014744	Walker A motif/ATP binding site; other site
585397014745	ATP binding site [chemical binding]; other site
585397014746	Walker B motif; other site
585397014747	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
585397014748	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397014749	non-specific DNA binding site [nucleotide binding]; other site
585397014750	salt bridge; other site
585397014751	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
585397014752	sequence-specific DNA binding site [nucleotide binding]; other site
585397014753	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
585397014754	active site
585397014755	(T/H)XGH motif; other site
585397014756	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
585397014757	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
585397014758	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585397014759	non-specific DNA binding site [nucleotide binding]; other site
585397014760	salt bridge; other site
585397014761	sequence-specific DNA binding site [nucleotide binding]; other site
585397014762	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
585397014763	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585397014764	Walker A/P-loop; other site
585397014765	ATP binding site [chemical binding]; other site
585397014766	Q-loop/lid; other site
585397014767	ABC transporter signature motif; other site
585397014768	Walker B; other site
585397014769	D-loop; other site
585397014770	H-loop/switch region; other site
585397014771	ABC transporter; Region: ABC_tran_2; pfam12848
585397014772	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
585397014773	lytic murein transglycosylase; Provisional; Region: PRK11619
585397014774	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
585397014775	N-acetyl-D-glucosamine binding site [chemical binding]; other site
585397014776	catalytic residue [active]
585397014777	Trp operon repressor; Provisional; Region: PRK01381
585397014778	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
585397014779	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
585397014780	catalytic core [active]
585397014781	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
585397014782	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585397014783	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
585397014784	hypothetical protein; Provisional; Region: PRK10756
585397014785	CreA protein; Region: CreA; pfam05981
585397014786	DNA-binding response regulator CreB; Provisional; Region: PRK11083
585397014787	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397014788	active site
585397014789	phosphorylation site [posttranslational modification]
585397014790	intermolecular recognition site; other site
585397014791	dimerization interface [polypeptide binding]; other site
585397014792	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585397014793	DNA binding site [nucleotide binding]
585397014794	sensory histidine kinase CreC; Provisional; Region: PRK11100
585397014795	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585397014796	dimerization interface [polypeptide binding]; other site
585397014797	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585397014798	dimer interface [polypeptide binding]; other site
585397014799	phosphorylation site [posttranslational modification]
585397014800	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585397014801	ATP binding site [chemical binding]; other site
585397014802	Mg2+ binding site [ion binding]; other site
585397014803	G-X-G motif; other site
585397014804	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
585397014805	two-component response regulator; Provisional; Region: PRK11173
585397014806	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585397014807	active site
585397014808	phosphorylation site [posttranslational modification]
585397014809	intermolecular recognition site; other site
585397014810	dimerization interface [polypeptide binding]; other site
585397014811	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585397014812	DNA binding site [nucleotide binding]
585397014813	putative RNA methyltransferase; Provisional; Region: PRK10433
585397014814	RNA methyltransferase, TrmH family, group 1; Region: rRNA_methyl_1; TIGR00050