-- dump date 20140619_082234 -- class Genbank::CDS -- table cds_note -- id note YP_001456786.1 identified by match to protein family HMM PF08254; match to protein family HMM TIGR02077 YP_001456787.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001456788.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_001456789.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001456790.1 identified by glimmer YP_001456791.1 yaaA; identified by similarity to SP:Q8ZS17; match to protein family HMM PF03883 YP_001456792.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_001456793.1 identified by match to protein family HMM PF00923; match to protein family HMM TIGR00874 YP_001456794.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_001456795.1 yaaH; identified by match to protein family HMM PF01184 YP_001456796.1 identified by match to protein family HMM PF03667 YP_001456797.1 yaaI YP_001456798.1 identified by glimmer YP_001456799.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001456800.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001456801.1 identified by match to protein family HMM PF01609 YP_001456802.1 identified by match to protein family HMM PF01848 YP_001456803.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_001456804.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_001456805.1 NULL; identified by similarity to GB:AAZ86820.1 YP_001456806.1 identified by glimmer YP_001456807.1 NULL; identified by glimmer YP_001456808.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001456809.1 yaaY; identified by similarity to GB:AAZ86826.1 YP_001456810.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_001456811.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme YP_001456812.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001456813.1 identified by match to protein family HMM PF00254 YP_001456814.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001456815.1 catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides YP_001456816.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001456817.1 identified by glimmer YP_001456818.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001456819.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001456820.1 identified by glimmer YP_001456821.1 regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons YP_001456822.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities YP_001456823.2 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA YP_001456824.1 identified by match to protein family HMM PF00501 YP_001456825.1 catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine YP_001456826.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA YP_001456827.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism YP_001456828.1 identified by glimmer YP_001456829.1 identified by similarity to GB:AAX63975.1 YP_001456830.1 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase YP_001456831.1 involved in electron transfer during carnitine metabolism YP_001456832.1 FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction YP_001456833.1 identified by similarity to SP:P68646 YP_001456834.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_001456835.1 Required for full activity of KefC, a potassium-proton antiporter YP_001456836.1 transport system that facilitates potassium-efflux YP_001456837.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate YP_001456838.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_001456839.1 protein associated with Co2+ and Mg2+ efflux YP_001456840.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001456841.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001456842.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB YP_001456843.1 determines N-hexane tolerance and is involved in outer membrane permeability YP_001456844.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_001456845.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs YP_001456846.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_001456847.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_001456848.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_001456849.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism YP_001456850.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate YP_001456851.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose YP_001456852.1 yabI; identified by similarity to SP:P30149; match to protein family HMM PF09335 YP_001456853.1 with TbpA and ThiP is part of the thiamine and TPP transport system YP_001456854.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine YP_001456855.1 part of the thiamine and TPP transport system tbpA-thiPQ YP_001456857.1 activates sgrS under glucose-phosphate stress conditions YP_001456858.1 identified by similarity to SP:P31675; match to protein family HMM PF07690; match to protein family HMM TIGR00899 YP_001456859.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001456860.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001456861.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001456862.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001456863.1 involved in attenuation control of the leuABCD operon in leucine biosynthesis YP_001456864.1 activator for leuABCD operon; member of LysR family of transcriptional activators YP_001456865.1 identified by glimmer YP_001456866.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive YP_001456867.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001456868.1 identified by glimmer YP_001456869.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism YP_001456870.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001456871.1 identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006 YP_001456872.1 membrane bound cell division protein at septum containing leucine zipper motif YP_001456873.1 identified by similarity to SP:P0AD68; match to protein family HMM PF00905; match to protein family HMM PF03717 YP_001456874.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001456875.1 identified by similarity to SP:P11880; match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01143 YP_001456876.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001456877.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001456878.1 integral membrane protein involved in stabilizing FstZ ring during cell division YP_001456879.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001456880.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001456881.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001456882.1 involved in septum formation YP_001456883.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane YP_001456884.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001456885.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001456886.1 secM translational pause allows for the initiation of secA translation YP_001456887.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001456888.1 identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586 YP_001456889.1 identified by similarity to SP:P0A8H8; match to protein family HMM PF03884 YP_001456890.1 yacF; identified by match to protein family HMM PF07072 YP_001456891.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_001456892.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate YP_001456893.1 identified by match to protein family HMM PF00482 YP_001456894.1 identified by match to protein family HMM PF00437 YP_001456895.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_001456896.1 identified by similarity to SP:P13016; match to protein family HMM PF01510 YP_001456897.1 involved in regulation of beta-lactamase; signaling protein YP_001456898.1 identified by similarity to SP:P15993; match to protein family HMM PF00324 YP_001456899.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_001456900.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_001456901.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains YP_001456902.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001456904.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001456905.1 yacL; identified by similarity to SP:P59396; match to protein family HMM PF06062 YP_001456906.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_001456907.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_001456908.1 yacC YP_001456909.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification YP_001456910.1 identified by similarity to SP:P15877; match to protein family HMM PF01011; match to protein family HMM TIGR03074 YP_001456911.1 identified by similarity to SP:P0A9M2; match to protein family HMM PF00156; match to protein family HMM TIGR01203 YP_001456912.1 catalyzes the interconversion of bicarbonate and carbon dioxide YP_001456913.1 identified by match to protein family HMM PF00005 YP_001456914.1 identified by match to protein family HMM PF01061 YP_001456915.1 identified by match to protein family HMM PF03610 YP_001456916.1 identified by match to protein family HMM PF01522 YP_001456917.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_001456918.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_001456919.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001456920.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001456921.1 identified by match to protein family HMM PF00419 YP_001456922.1 identified by similarity to GB:AAZ86939.1 YP_001456923.1 identified by similarity to GB:AAP17067.1; match to protein family HMM PF00665 YP_001456924.1 identified by similarity to GB:AAP19558.1; match to protein family HMM PF01527 YP_001456925.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001456926.1 catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP YP_001456927.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's YP_001456928.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu YP_001456929.1 identified by match to protein family HMM PF01258; match to protein family HMM TIGR02420 YP_001456930.1 Regulatory factor involved in maltose metabolism YP_001456931.1 identified by similarity to SP:P37025; match to protein family HMM PF02834; match to protein family HMM TIGR02258 YP_001456932.1 similar in sequence to the ATP-dependent RNA helicase HrpA YP_001456933.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell YP_001456934.1 identified by glimmer YP_001456935.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein YP_001456936.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter YP_001456937.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores YP_001456938.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_001456939.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001456940.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation YP_001456941.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_001456942.1 yadS; identified by match to protein family HMM PF03458 YP_001456943.1 solute binding component of the vitamin B12 transport system BtuCDF YP_001456944.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_001456945.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate YP_001456946.1 protease Do; required at high temperature; degrades damaged proteins YP_001456947.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization YP_001456949.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_001456950.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_001456951.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_001456952.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001456953.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001456954.1 Catalyzes the phosphorylation of UMP to UDP YP_001456955.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001456956.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001456957.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_001456958.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate YP_001456959.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response YP_001456960.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins YP_001456961.1 identified by similarity to SP:P31519; match to protein family HMM PF03938 YP_001456962.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001456963.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001456964.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001456965.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001456966.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001456967.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001456968.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_001456969.1 identified by similarity to SP:P52095; match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_001456970.1 identified by match to protein family HMM PF00903 YP_001456971.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase YP_001456972.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination YP_001456973.1 identified by match to protein family HMM PF06786 YP_001456974.1 yaeQ; identified by match to protein family HMM PF07152 YP_001456975.1 yaeJ; identified by match to protein family HMM PF00472 YP_001456976.1 identified by similarity to SP:P40710; match to protein family HMM PF04170 YP_001456977.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001456978.1 yaeF; identified by similarity to GB:ABB60443.1 YP_001456979.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001456980.1 NULL; identified by match to protein family HMM PF01980; match to protein family HMM TIGR00104 YP_001456982.1 identified by match to protein family HMM PF03180; match to protein family HMM TIGR00363 YP_001456983.1 part of the MetNIQ methionine uptake system YP_001456984.1 part of the metNIQ transport system for methionine YP_001456985.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_001456986.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid YP_001456987.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001456988.1 yafD; identified by match to protein family HMM PF03372 YP_001456989.1 identified by match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_001456990.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall YP_001456991.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione YP_001456992.1 yafS; identified by similarity to GB:AAV78381.1; match to protein family HMM PF08241 YP_001456993.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_001456994.1 3'-5' exonuclease of DNA polymerase III YP_001456995.1 identified by glimmer YP_001456997.1 yafU; identified by similarity to GB:CAH22064.1 YP_001456998.1 identified by match to protein family HMM PF05638; match to protein family HMM TIGR03344 YP_001456999.1 identified by similarity to GB:AAZ87018.1; match to protein family HMM PF06812 YP_001457000.1 identified by match to protein family HMM PF06744; match to protein family HMM PF06761; match to protein family HMM TIGR03348 YP_001457001.1 identified by match to protein family HMM PF06812; match to protein family HMM TIGR03362 YP_001457002.1 NULL; identified by match to protein family HMM TIGR03360 YP_001457003.1 identified by match to protein family HMM PF00004; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03345 YP_001457004.1 NULL; identified by similarity to GB:AAN68224.1; match to protein family HMM TIGR03349 YP_001457005.1 NULL; identified by similarity to GB:AAM83869.1; match to protein family HMM PF05936; match to protein family HMM TIGR03353 YP_001457006.1 NULL; identified by match to protein family HMM TIGR03352 YP_001457007.1 NULL; identified by similarity to GB:CAG76339.1; match to protein family HMM TIGR03354 YP_001457008.1 NULL; identified by similarity to GB:CAH22872.1; match to protein family HMM PF06996; match to protein family HMM TIGR03347 YP_001457009.1 NULL; identified by similarity to GB:CAG76341.1; match to protein family HMM PF05947; match to protein family HMM TIGR03359 YP_001457010.1 NULL; identified by similarity to GB:CAG76342.1; match to protein family HMM PF04965; match to protein family HMM TIGR03357 YP_001457011.1 NULL; identified by similarity to GB:CAH22875.1; match to protein family HMM PF05943; match to protein family HMM TIGR03355 YP_001457012.1 NULL; identified by glimmer YP_001457013.1 NULL; identified by similarity to GB:CAH22876.1; match to protein family HMM PF05591; match to protein family HMM TIGR03358 YP_001457014.1 NULL; identified by glimmer YP_001457015.1 NULL; identified by match to protein family HMM PF05638; match to protein family HMM TIGR03344 YP_001457016.1 identified by glimmer YP_001457017.1 identified by match to protein family HMM PF04524; match to protein family HMM PF06715; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361 YP_001457018.1 identified by similarity to GB:AAC32471.1; match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643 YP_001457019.1 identified by glimmer YP_001457020.1 identified by match to protein family HMM PF00795 YP_001457021.1 inactivates vertebrate C-type lysozyme YP_001457022.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001457023.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_001457024.1 identified by match to protein family HMM PF00310 YP_001457025.1 yafK; identified by match to protein family HMM PF06104 YP_001457026.1 yafQ; identified by similarity to GB:AAZ87051.1; match to protein family HMM PF05016; match to protein family HMM TIGR00053; match to protein family HMM TIGR02385 YP_001457027.1 identified by match to protein family HMM PF04221; match to protein family HMM TIGR02384 YP_001457028.1 identified by match to protein family HMM PF00877 YP_001457029.1 identified by match to protein family HMM PF05534 YP_001457030.1 identified by similarity to GB:CAE13002.1 YP_001457031.1 identified by match to protein family HMM PF00771 YP_001457032.1 identified by match to protein family HMM PF00691 YP_001457033.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001457034.1 identified by match to protein family HMM PF00583 YP_001457035.1 mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY YP_001457036.1 similar to release factor 1 and 2 YP_001457037.1 identified by similarity to SP:P15288; match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01893 YP_001457038.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_001457039.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation YP_001457040.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS YP_001457041.1 identified by similarity to SP:P02932; match to protein family HMM PF00267; match to protein family HMM TIGR03304 YP_001457042.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001457043.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001457044.1 identified by match to protein family HMM PF00589 YP_001457046.1 identified by match to protein family HMM PF04447; match to protein family HMM PF04448 YP_001457047.1 identified by match to protein family HMM PF04447 YP_001457049.1 identified by glimmer YP_001457050.1 phage protein like Prophage functions; identified by glimmer YP_001457052.1 identified by match to protein family HMM PF01527 YP_001457053.1 identified by similarity to GB:AAP17067.1; match to protein family HMM PF00665 YP_001457054.1 Gp46 protein like similar to bacteriophage protein YP_001457055.1 identified by similarity to SP:P33228; match to protein family HMM PF03837; match to protein family HMM TIGR00616 YP_001457056.1 phage protein YP_001457057.1 identified by glimmer YP_001457058.1 identified by glimmer YP_001457059.1 identified by glimmer YP_001457060.1 identified by glimmer YP_001457061.1 identified by similarity to SP:P69202; match to protein family HMM PF00717; match to protein family HMM PF01381 YP_001457062.1 identified by similarity to SP:P09964 YP_001457063.1 identified by match to protein family HMM PF05269 YP_001457064.1 identified by similarity to GB:CAC83138.1 YP_001457065.1 identified by match to protein family HMM PF00772; match to protein family HMM PF03796 YP_001457066.1 identified by match to protein family HMM PF05772 YP_001457067.1 identified by match to protein family HMM PF05322 YP_001457068.1 similar to bacteriophage P22 ninX no additional details recorded YP_001457069.1 identified by match to protein family HMM PF05810 YP_001457071.1 identified by match to protein family HMM PF07102 YP_001457072.1 identified by similarity to SP:Q9MCN8; match to protein family HMM PF05866 YP_001457073.1 identified by match to protein family HMM PF06322 YP_001457074.1 identified by similarity to SP:P03047; match to protein family HMM PF03589 YP_001457075.1 identified by match to protein family HMM PF05106; match to protein family HMM TIGR01594 YP_001457076.1 identified by match to protein family HMM PF00959 YP_001457077.1 identified by match to protein family HMM PF03245 YP_001457078.1 identified by match to protein family HMM TIGR02681 YP_001457081.1 identified by match to protein family HMM PF04466; match to protein family HMM PF07570; match to protein family HMM TIGR01547 YP_001457082.1 portal protein-like YP_001457083.1 identified by glimmer YP_001457084.1 coat protein-like; identified by glimmer YP_001457090.1 identified by similarity to SP:Q9AYZ1 YP_001457091.1 identified by similarity to SP:Q01076 YP_001457092.1 identified by similarity to GB:AAX64270.1 YP_001457093.1 identified by glimmer YP_001457094.1 identified by similarity to SP:P69202; match to protein family HMM PF00717; match to protein family HMM PF01381 YP_001457097.1 identified by match to protein family HMM PF01527 YP_001457098.1 identified by similarity to GB:AAP17067.1; match to protein family HMM PF00665 YP_001457099.1 bifunctional tail protein-like; identified by match to protein family HMM PF09008 YP_001457100.1 protein UmuD-like YP_001457101.1 identified by match to protein family HMM PF00589 YP_001457102.1 identified by match to protein family HMM PF02384 YP_001457104.1 identified by glimmer YP_001457105.1 identified by match to protein family HMM PF03400 YP_001457106.1 identified by glimmer YP_001457107.1 identified by similarity to GB:AAM08040.1; match to protein family HMM PF08849 YP_001457108.1 identified by match to protein family HMM PF08747 YP_001457110.1 identified by similarity to GB:AAL23313.1 YP_001457111.1 identified by match to protein family HMM PF08665; match to protein family HMM TIGR02687 YP_001457112.1 identified by match to protein family HMM TIGR02653; match to protein family HMM TIGR02688 YP_001457113.1 identified by glimmer YP_001457114.1 identified by similarity to GB:CAG75764.1 YP_001457115.1 identified by glimmer YP_001457116.1 identified by glimmer YP_001457117.1 identified by match to protein family HMM PF01527 YP_001457118.1 identified by similarity to GB:AAP17067.1; match to protein family HMM PF00665 YP_001457119.1 identified by match to protein family HMM PF00196 YP_001457120.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif YP_001457121.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001457122.1 identified by similarity to SP:P36943; match to protein family HMM PF02369 YP_001457123.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445 YP_001457124.1 identified by match to protein family HMM PF00248 YP_001457125.1 ykgB; identified by match to protein family HMM PF04224 YP_001457127.1 Involved in disulfide oxidoreductase activity and electron transport YP_001457128.1 identified by glimmer YP_001457129.1 identified by match to protein family HMM PF00165 YP_001457130.1 identified by match to protein family HMM PF02754 YP_001457131.1 identified by match to protein family HMM PF02589; match to protein family HMM TIGR00273 YP_001457132.1 ykgG; identified by similarity to GB:AAP15803.1; match to protein family HMM PF02589 YP_001457133.1 NULL YP_001457134.1 NULL; identified by match to protein family HMM PF03797; match to protein family HMM TIGR01414 YP_001457136.1 identified by match to protein family HMM PF00196 YP_001457137.1 identified by match to protein family HMM PF00589 YP_001457138.1 identified by match to protein family HMM PF03811 YP_001457139.1 identified by glimmer YP_001457140.1 NULL; identified by glimmer YP_001457141.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_001457142.1 catalyzes the formation of betaine from betaine aldehyde YP_001457143.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes YP_001457144.1 proton-motive-force-driven choline transporter YP_001457145.1 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414; match to protein family HMM TIGR03304 YP_001457146.1 identified by match to protein family HMM PF00196; match to protein family HMM PF00563 YP_001457147.1 NULL; identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001457148.1 NULL; identified by similarity to SP:P77219; match to protein family HMM PF06496 YP_001457149.1 identified by similarity to GB:AAN78919.1 YP_001457150.1 identified by match to protein family HMM PF00023 YP_001457151.1 yahE; identified by similarity to GB:AAZ87092.1 YP_001457152.1 identified by match to protein family HMM PF06263 YP_001457153.1 yahG; identified by match to protein family HMM PF06545 YP_001457154.1 yahI; identified by match to protein family HMM PF00696 YP_001457155.1 identified by match to protein family HMM PF07969 YP_001457156.1 NULL; identified by match to protein family HMM PF06171 YP_001457158.1 identified by match to protein family HMM PF00005 YP_001457159.1 identified by match to protein family HMM PF02653 YP_001457160.1 identified by match to protein family HMM PF02653 YP_001457161.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001457162.1 yahL; identified by similarity to GB:AAZ87085.1 YP_001457163.1 NULL; identified by glimmer YP_001457164.1 yahN; identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949 YP_001457165.1 yahO; identified by match to protein family HMM PF07338 YP_001457166.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM PF06506; match to protein family HMM TIGR02329 YP_001457167.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_001457168.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity YP_001457169.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C YP_001457170.1 catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent YP_001457171.1 identified by match to protein family HMM PF02133; match to protein family HMM TIGR00800 YP_001457172.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_001457173.1 controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source YP_001457174.1 identified by match to protein family HMM PF00484 YP_001457175.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide YP_001457176.1 MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon; not essential YP_001457177.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments YP_001457178.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon YP_001457179.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer YP_001457180.1 activator of 3-phenylpropionic acid catabolism YP_001457181.1 catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate YP_001457182.1 catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase YP_001457183.1 identified by similarity to SP:P77044; match to protein family HMM PF00561 YP_001457184.1 catalyzes the formation of 2-keto-4-hydroxypentanoic acid from 2-hydroxypentadienoic acid YP_001457185.1 catalyzes the formation of acetyl-CoA from acetalaldehyde YP_001457186.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate YP_001457187.1 identified by similarity to SP:P77589; match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00895 YP_001457189.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001457190.1 identified by match to protein family HMM PF00756; match to protein family HMM TIGR02821 YP_001457191.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818 YP_001457192.1 formaldehyde-induced negative regulator of the frmRAB operon YP_001457193.1 yaiO; identified by glimmer YP_001457194.1 identified by match to protein family HMM PF00132 YP_001457195.1 yaiP; identified by match to protein family HMM PF00535 YP_001457196.1 yaiS; identified by match to protein family HMM PF02585 YP_001457197.1 identified by glimmer YP_001457198.1 identified by similarity to GB:AAN78949.1 YP_001457199.1 with TauB and TauC is responsible for taurine uptake. YP_001457200.1 Part of the ABC transporter complex tauABC involved in taurine import YP_001457201.1 identified by match to protein family HMM PF00528 YP_001457202.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers YP_001457203.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001457205.1 identified by similarity to GB:AAP17067.1; match to protein family HMM PF00665 YP_001457206.1 identified by match to protein family HMM PF01527 YP_001457207.1 identified by match to protein family HMM PF03797; match to protein family HMM TIGR01414; match to protein family HMM TIGR03304 YP_001457208.1 yaiV; identified by glimmer YP_001457209.1 this protein has no known enzymatic function YP_001457210.1 identified by glimmer YP_001457211.1 identified by glimmer YP_001457212.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope YP_001457213.1 yaiW; identified by match to protein family HMM PF07759 YP_001457214.1 yaiY; identified by similarity to SP:P0AAP7 YP_001457215.1 yaiZ; identified by similarity to GB:AAZ87131.1; similarity to GB:CAD08834.1 YP_001457216.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001457217.1 identified by glimmer YP_001457218.1 identified by glimmer YP_001457219.1 yaiB YP_001457220.1 identified by similarity to SP:P00634; match to protein family HMM PF00245 YP_001457221.1 identified by similarity to SP:P27295; match to protein family HMM PF07769 YP_001457222.1 catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis YP_001457223.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_001457224.1 identified by similarity to SP:Q3Z523; match to protein family HMM PF02639 YP_001457225.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001457226.1 yaiA YP_001457227.1 identified by similarity to SP:P08403; match to protein family HMM PF07302 YP_001457228.1 ykiA; identified by glimmer YP_001457229.1 Required for efficient pilin antigenic variation YP_001457230.1 catalyzes phosphorylation of fructose; cytosolic enzyme YP_001457231.1 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers YP_001457232.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity YP_001457233.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity YP_001457234.1 identified by glimmer YP_001457235.1 two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB YP_001457236.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB YP_001457237.1 identified by glimmer YP_001457238.1 identified by similarity to GB:AAX64346.1 YP_001457239.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_001457240.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation YP_001457241.1 identified by similarity to SP:P21517; match to protein family HMM PF00128 YP_001457242.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP YP_001457243.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001457244.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001457245.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_001457246.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001457247.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001457248.1 yajD; identified by match to protein family HMM PF01844 YP_001457249.1 identified by similarity to GB:ABB67500.1 YP_001457250.1 identified by match to protein family HMM PF03502 YP_001457251.1 yajI; identified by similarity to GB:CAD08870.1 YP_001457252.1 identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244 YP_001457253.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil YP_001457254.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001457255.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001457256.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_001457257.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate YP_001457258.1 identified by match to protein family HMM PF00248 YP_001457259.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001457260.1 identified by similarity to SP:P22939; match to protein family HMM PF00348 YP_001457261.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_001457262.1 identified by glimmer YP_001457263.1 Required for the synthesis of the thiazole moiety YP_001457264.1 identified by similarity to SP:Q46948; match to protein family HMM PF01965; match to protein family HMM TIGR01383 YP_001457265.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_001457266.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_001457267.1 identified by match to protein family HMM PF07690 YP_001457268.1 identified by match to protein family HMM PF08238 YP_001457269.1 identified by match to protein family HMM PF00583 YP_001457270.1 identified by match to protein family HMM PF08681 YP_001457271.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001457272.1 identified by similarity to SP:P0ABJ6; match to protein family HMM PF03626; match to protein family HMM TIGR02847 YP_001457273.1 identified by similarity to SP:P0ABJ3; match to protein family HMM PF00510; match to protein family HMM TIGR02842 YP_001457274.1 identified by match to protein family HMM PF00115; match to protein family HMM TIGR02843 YP_001457275.1 identified by similarity to SP:P0ABJ1; match to protein family HMM PF00116; match to protein family HMM PF06481; match to protein family HMM TIGR01433 YP_001457276.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein YP_001457277.1 identified by match to protein family HMM PF03923 YP_001457278.1 identified by glimmer YP_001457279.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress YP_001457280.1 identified by glimmer YP_001457281.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001457282.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001457283.1 binds and unfolds substrates as part of the ClpXP protease YP_001457284.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02190; match to protein family HMM PF05362; match to protein family HMM PF07728; match to protein family HMM TIGR00763 YP_001457285.1 histone-like DNA-binding protein YP_001457286.1 identified by similarity to SP:P0ADY1; match to protein family HMM PF00639; match to protein family HMM PF09312 YP_001457287.1 identified by match to protein family HMM TIGR00426 YP_001457288.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00051 YP_001457289.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His YP_001457290.1 identified by match to protein family HMM PF00496 YP_001457291.1 identified by similarity to SP:P46891; match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_001457292.1 identified by match to protein family HMM PF01037 YP_001457293.1 identified by similarity to SP:P77265; match to protein family HMM PF00005; match to protein family HMM PF00664 YP_001457294.1 identified by similarity to SP:P0AAG5; match to protein family HMM PF00005; match to protein family HMM PF00664 YP_001457295.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia. YP_001457296.1 identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836 YP_001457297.1 identified by match to protein family HMM PF02551; match to protein family HMM TIGR00189 YP_001457299.1 identified by match to protein family HMM PF01035; match to protein family HMM TIGR00589 YP_001457300.1 ybaA; identified by match to protein family HMM PF07237 YP_001457301.1 identified by match to protein family HMM PF00563 YP_001457302.1 ylaC YP_001457303.1 identified by similarity to SP:P77791; match to protein family HMM PF00132 YP_001457304.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins YP_001457305.1 ybaJ; identified by similarity to GB:AAV78134.1 YP_001457306.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_001457307.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730 YP_001457308.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine YP_001457309.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS YP_001457310.1 identified by glimmer YP_001457311.1 ybaM; identified by similarity to RF:NP_455077.1 YP_001457312.1 PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks YP_001457313.1 identified by match to protein family HMM PF04304 YP_001457314.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001457315.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_001457316.1 ybaB; identified by similarity to GB:AAZ90762.1; match to protein family HMM PF02575; match to protein family HMM TIGR00103 YP_001457317.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001457318.1 molecular chaperone YP_001457319.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001457320.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001457321.1 identified by similarity to SP:P23872; match to protein family HMM PF07859 YP_001457322.1 identified by similarity to SP:P0AEW6; match to protein family HMM PF00294 YP_001457323.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein YP_001457324.1 identified by match to protein family HMM PF07690 YP_001457325.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_001457326.1 identified by match to protein family HMM PF04073; match to protein family HMM TIGR00011 YP_001457327.1 identified by match to protein family HMM PF07446 YP_001457328.1 identified by match to protein family HMM PF01381; match to protein family HMM TIGR02607 YP_001457329.1 identified by glimmer YP_001457330.1 identified by glimmer YP_001457331.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525 YP_001457332.1 catalyzes the formation of glutamate from glutamine YP_001457333.1 ybaT; identified by match to protein family HMM PF00324; match to protein family HMM PF01490; match to protein family HMM PF03845 YP_001457334.1 activator of copper-responsive regulon genes YP_001457335.1 ybbJ; identified by match to protein family HMM PF01957 YP_001457336.1 identified by match to protein family HMM PF01145 YP_001457337.1 identified by match to protein family HMM PF00005 YP_001457338.1 identified by match to protein family HMM PF03649; match to protein family HMM TIGR00245 YP_001457339.1 identified by similarity to SP:P77395; match to protein family HMM PF00085 YP_001457340.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_001457341.1 identified by similarity to SP:P0ADA1; match to protein family HMM PF00657 YP_001457342.1 identified by match to protein family HMM PF00005 YP_001457343.1 identified by match to protein family HMM PF02687 YP_001457344.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_001457345.1 activator of the allDC-ylbA operon involved in allantoin utilization YP_001457346.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate YP_001457347.1 regulates operons involved in the utilization of allantoin YP_001457348.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate YP_001457349.1 identified by similarity to SP:P30147; match to protein family HMM PF01261; match to protein family HMM TIGR03234 YP_001457350.1 identified by match to protein family HMM PF03446; match to protein family HMM TIGR01505 YP_001457351.1 identified by match to protein family HMM PF02133; match to protein family HMM TIGR00800 YP_001457352.1 Plays a crucial role on both purine and pyrimidine metabolism YP_001457353.1 identified by match to protein family HMM PF00860 YP_001457354.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045 YP_001457355.1 identified by glimmer YP_001457356.1 ylbA; identified by similarity to GB:CAD05010.1; match to protein family HMM PF05899; match to protein family HMM PF07883; match to protein family HMM TIGR03214 YP_001457357.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001457358.1 identified by similarity to SP:P77555; match to protein family HMM PF02615; match to protein family HMM TIGR03175 YP_001457359.1 multicopy suppressor of dominant negative ftsH mutations YP_001457360.1 ylbE; identified by match to protein family HMM PF06545 YP_001457361.1 ylbF YP_001457362.1 identified by match to protein family HMM PF00696; match to protein family HMM TIGR00746 YP_001457363.1 identified by glimmer YP_001457364.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_001457365.1 identified by similarity to SP:P0AG18; match to protein family HMM PF00731; match to protein family HMM TIGR01162 YP_001457366.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_001457367.1 identified by similarity to SP:P23869; match to protein family HMM PF00160 YP_001457368.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001457369.1 ybcI; identified by match to protein family HMM PF04307 YP_001457370.1 identified by similarity to SP:P24186; match to protein family HMM PF00763; match to protein family HMM PF02882 YP_001457371.1 identified by similarity to SP:P04128; match to protein family HMM PF00419 YP_001457372.1 identified by glimmer YP_001457373.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001457374.1 identified by similarity to SP:P30130; match to protein family HMM PF00577 YP_001457375.1 identified by similarity to GB:AAD17914.1 YP_001457376.1 identified by similarity to SP:P37921; match to protein family HMM PF00419 YP_001457377.1 activates the production of the major fimbrae protein FimA YP_001457378.1 NULL; identified by similarity to GB:CAE12649.1; match to protein family HMM PF08786 YP_001457379.1 identified by match to protein family HMM PF04524; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361 YP_001457380.1 identified by similarity to SP:P77485; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR01386 YP_001457381.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system YP_001457382.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver YP_001457383.1 ylcC YP_001457384.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver YP_001457385.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00914 YP_001457386.1 identified by similarity to SP:P24207; match to protein family HMM PF00324 YP_001457387.1 identified by match to protein family HMM PF00924 YP_001457388.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive YP_001457389.1 ybdF; identified by similarity to GB:BAA35219.1; match to protein family HMM PF04237 YP_001457390.1 ybdJ; identified by match to protein family HMM PF06643 YP_001457391.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity YP_001457392.1 identified by match to protein family HMM PF01848 YP_001457393.1 identified by match to protein family HMM PF01609 YP_001457394.1 identified by similarity to SP:P19925; match to protein family HMM PF01648 YP_001457395.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space YP_001457396.1 identified by glimmer YP_001457397.1 identified by similarity to SP:P13039; match to protein family HMM PF00756 YP_001457398.1 identified by match to protein family HMM PF03621 YP_001457399.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin YP_001457400.1 identified by glimmer YP_001457401.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake YP_001457402.1 with FepBDE is involved in the transport of ferric enterobactin YP_001457403.1 with FepBCD is involved in the transport of ferric enterobactin YP_001457404.1 with FepBCG is involved in the transport of ferric enterobactin YP_001457405.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters YP_001457406.1 with FepCDG is involved in the transport of ferric enterobactin YP_001457407.1 identified by similarity to SP:P0AEJ2; match to protein family HMM PF00425; match to protein family HMM TIGR00543 YP_001457408.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate YP_001457409.1 identified by similarity to SP:P0ADI4; match to protein family HMM PF00550; match to protein family HMM PF00857 YP_001457410.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin YP_001457411.1 ybdB; identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_001457412.1 identified by similarity to SP:P15078; match to protein family HMM PF02554 YP_001457413.1 identified by similarity to SP:P0AAT1; match to protein family HMM PF04328 YP_001457414.1 member of the iron-containing alcohol dehydrogenase; unknown function YP_001457415.1 catalyzes the transfer of an amino moiety YP_001457416.1 ybdM; identified by match to protein family HMM PF02195 YP_001457417.1 ybdN; identified by match to protein family HMM PF01507 YP_001457418.1 identified by match to protein family HMM PF00126 YP_001457419.1 Involved in disulfide bond formation YP_001457420.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate YP_001457421.1 identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR03140 YP_001457422.1 ybdQ; identified by similarity to SP:P39177; match to protein family HMM PF00582 YP_001457423.1 identified by similarity to SP:P77316; match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001457424.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation YP_001457425.1 identified by similarity to SP:P21338; match to protein family HMM PF00445 YP_001457426.1 identified by match to protein family HMM PF00939; match to protein family HMM TIGR00785 YP_001457427.1 catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA YP_001457428.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate YP_001457429.1 identified by match to protein family HMM PF04223; match to protein family HMM TIGR01584 YP_001457430.1 identified by match to protein family HMM PF03328; match to protein family HMM TIGR01588 YP_001457431.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate YP_001457432.1 identified by similarity to SP:P77390; match to protein family HMM PF00583; match to protein family HMM PF08218; match to protein family HMM TIGR00124; match to protein family HMM TIGR00125 YP_001457433.1 identified by similarity to SP:P77510; match to protein family HMM PF02518 YP_001457434.1 regulates the expression of citAB in citrate fermentation YP_001457435.1 identified by glimmer YP_001457436.1 catalyzes the transfer of palmitate to lipid A YP_001457437.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator YP_001457438.1 identified by similarity to SP:P37002; match to protein family HMM PF02537; match to protein family HMM TIGR00494 YP_001457439.1 ybeH; identified by match to protein family HMM PF00795 YP_001457440.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001457441.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001457442.1 identified by glimmer YP_001457443.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001457444.1 lipoyl-[acyl-carrier protein]-protein-N-lipoyltransferse; lipoate-protein ligase B; transfers lipoate to apolipoproteins; involved in lipoate metabolism YP_001457445.1 ybeD; identified by similarity to SP:P0A8J4; match to protein family HMM PF04359 YP_001457446.1 identified by similarity to SP:P10100; match to protein family HMM PF03330; match to protein family HMM PF05036; match to protein family HMM TIGR00413 YP_001457447.1 identified by similarity to SP:P0ABG7; match to protein family HMM PF01098; match to protein family HMM TIGR02210 YP_001457448.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM TIGR03423 YP_001457449.1 SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_001457450.1 identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090 YP_001457451.1 identified by similarity to SP:P52086; match to protein family HMM PF00300; match to protein family HMM TIGR03162 YP_001457452.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_001457453.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_001457454.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane YP_001457455.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001457456.1 identified by similarity to SP:P0AAT9; match to protein family HMM PF07295 YP_001457457.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific YP_001457458.1 identified by match to protein family HMM PF00005 YP_001457459.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001457460.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001457461.1 identified by match to protein family HMM PF00497 YP_001457462.1 identified by glimmer YP_001457463.1 Transfers the fatty acyl group on membrane lipoproteins YP_001457464.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471 YP_001457465.1 identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043 YP_001457466.1 identified by match to protein family HMM PF02562 YP_001457467.1 identified by match to protein family HMM PF00919; match to protein family HMM PF01938; match to protein family HMM PF04055; match to protein family HMM TIGR00089; match to protein family HMM TIGR01574 YP_001457468.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q YP_001457469.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_001457470.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001457471.1 identified by similarity to SP:P15302; match to protein family HMM PF00702; match to protein family HMM TIGR01460 YP_001457472.1 identified by match to protein family HMM PF00480 YP_001457473.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate YP_001457474.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_001457475.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001457476.1 identified by glimmer YP_001457477.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001457478.1 identified by glimmer YP_001457479.1 ybfM; identified by match to protein family HMM PF03573 YP_001457480.1 ybfN YP_001457481.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_001457482.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001457483.1 ybfE; identified by match to protein family HMM PF01402 YP_001457484.1 identified by similarity to SP:P75736; match to protein family HMM PF00561; match to protein family HMM PF07819 YP_001457485.1 negative modulator of the initiation of chromosome replication YP_001457486.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001457487.1 identified by glimmer YP_001457489.1 identified by match to protein family HMM PF03811 YP_001457490.1 identified by match to protein family HMM PF03400 YP_001457491.1 NULL; identified by similarity to GB:AAN42241.1 YP_001457492.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport YP_001457493.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein YP_001457494.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex YP_001457495.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001457496.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001457497.1 identified by match to protein family HMM TIGR02115 YP_001457498.1 ybfA; identified by similarity to GB:AAN79258.1 YP_001457499.1 identified by similarity to SP:P16918; match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643 YP_001457500.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593 YP_001457501.1 ybfC; identified by glimmer YP_001457502.1 identified by similarity to GB:BAA35363.1 YP_001457503.1 identified by match to protein family HMM PF01609 YP_001457504.1 ybgA; identified by similarity to GB:AAN79259.1; match to protein family HMM PF08349 YP_001457505.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent YP_001457506.1 identified by glimmer YP_001457507.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924 YP_001457508.1 ybgI; identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486 YP_001457509.1 identified by match to protein family HMM PF02682; match to protein family HMM TIGR00370 YP_001457510.1 identified by match to protein family HMM PF02626; match to protein family HMM TIGR00724 YP_001457511.1 identified by match to protein family HMM PF03746 YP_001457512.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity YP_001457513.1 identified by match to protein family HMM PF05145; match to protein family HMM TIGR03082 YP_001457514.1 ybgO YP_001457515.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001457516.1 identified by match to protein family HMM PF00577 YP_001457517.1 identified by similarity to SP:P04128; match to protein family HMM PF00419 YP_001457518.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_001457519.1 identified by match to protein family HMM PF01127; match to protein family HMM TIGR02970 YP_001457520.1 identified by match to protein family HMM TIGR02968 YP_001457521.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001457522.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001457523.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001457524.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_001457525.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001457526.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_001457527.1 regulates the succiny-lCoA synthetase operon YP_001457528.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001457529.1 identified by match to protein family HMM PF03400 YP_001457530.1 identified by match to protein family HMM PF03811 YP_001457531.1 identified by similarity to GB:AAZ87440.1 YP_001457532.1 identified by glimmer YP_001457533.1 identified by match to protein family HMM PF01654 YP_001457534.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203 YP_001457535.1 identified by match to protein family HMM PF08173; match to protein family HMM TIGR02106 YP_001457536.1 ybgE; identified by match to protein family HMM TIGR02112 YP_001457537.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components YP_001457538.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_001457539.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_001457540.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins YP_001457541.1 identified by match to protein family HMM PF00691; match to protein family HMM TIGR02802 YP_001457542.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity YP_001457543.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001457544.1 identified by match to protein family HMM PF04973; match to protein family HMM TIGR01528 YP_001457545.1 involved in zinc efflux across the cytoplasmic membrane YP_001457547.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001457548.1 identified by similarity to SP:P62707; match to protein family HMM PF00300; match to protein family HMM TIGR01258 YP_001457549.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose YP_001457550.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism YP_001457551.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P YP_001457552.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF05368; match to protein family HMM PF07993; match to protein family HMM TIGR01179 YP_001457553.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum YP_001457554.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons YP_001457555.1 ybhT YP_001457556.1 with ModCB is involved in the high-affinity transport of molybdate YP_001457557.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE YP_001457558.1 Part of the ABC transporter complex modABC involved in molybdenum import YP_001457559.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily YP_001457560.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate YP_001457561.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001457562.1 ybhH; identified by similarity to SP:P0AAV8; match to protein family HMM PF04303 YP_001457563.1 identified by match to protein family HMM PF00939; match to protein family HMM PF03600; match to protein family HMM TIGR00785 YP_001457564.1 identified by match to protein family HMM PF00330; match to protein family HMM PF00694 YP_001457565.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase YP_001457566.1 YbhB; similar to rat and human kinase inhibitory proteins YP_001457567.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_001457568.1 identified by similarity to SP:P12996; match to protein family HMM PF04055; match to protein family HMM PF06968; match to protein family HMM TIGR00433 YP_001457569.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_001457570.1 methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth YP_001457571.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_001457572.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001457573.1 identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826 YP_001457574.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001457575.1 identified by similarity to SP:P30746; match to protein family HMM PF00994; match to protein family HMM TIGR00177; match to protein family HMM TIGR02667 YP_001457576.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001457577.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_001457578.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_001457579.1 ybhL; identified by match to protein family HMM PF01027 YP_001457580.1 ybhM; identified by match to protein family HMM PF01027 YP_001457581.1 ybhN YP_001457582.1 identified by similarity to SP:P0AA84; match to protein family HMM PF00614 YP_001457583.1 identified by match to protein family HMM PF03372 YP_001457584.1 ybhQ YP_001457585.1 ybhR; identified by match to protein family HMM PF01061 YP_001457586.1 ybhS; identified by match to protein family HMM PF01061 YP_001457587.1 identified by match to protein family HMM PF00005 YP_001457588.1 identified by match to protein family HMM PF00529 YP_001457589.1 identified by match to protein family HMM PF00440; match to protein family HMM PF09209 YP_001457590.1 this helicase is not essential cell growth YP_001457591.1 identified by glimmer YP_001457592.1 identified by similarity to GB:CAD72180.1; match to protein family HMM PF08719; match to protein family HMM TIGR02464 YP_001457593.1 helicase involved in DNA repair and perhaps also replication YP_001457594.1 identified by match to protein family HMM PF02885 YP_001457595.1 identified by similarity to PDB:2G8Y_A; match to protein family HMM PF02615 YP_001457596.1 ybiJ; identified by match to protein family HMM PF07338 YP_001457597.1 identified by match to protein family HMM PF01258 YP_001457598.1 identified by match to protein family HMM PF03171 YP_001457599.1 Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein YP_001457600.1 ybiM; identified by match to protein family HMM PF07338 YP_001457601.1 ybiN; identified by match to protein family HMM PF05971 YP_001457602.1 identified by match to protein family HMM PF00924 YP_001457603.1 identified by glimmer YP_001457604.1 similar to ATP-binding component of ABC transporters YP_001457605.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine YP_001457606.1 similar to periplasmic-binding component of ABC transporters YP_001457607.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage YP_001457608.1 identified by glimmer YP_001457609.1 identified by similarity to SP:P0AA67; match to protein family HMM PF00892 YP_001457610.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains YP_001457611.1 identified by match to protein family HMM PF00884 YP_001457613.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present YP_001457614.1 ybiR; identified by match to protein family HMM PF03600 YP_001457615.1 identified by similarity to SP:P0AAX8; match to protein family HMM PF03734 YP_001457616.1 identified by match to protein family HMM PF00005 YP_001457617.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001457618.1 ybiU; identified by match to protein family HMM PF07350 YP_001457619.1 identified by similarity to SP:P75792; match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_001457620.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01774 YP_001457621.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494 YP_001457622.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies YP_001457623.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_001457624.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum YP_001457625.1 NULL; identified by similarity to SP:P37595; match to protein family HMM PF01112 YP_001457626.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains YP_001457627.1 identified by similarity to SP:P75797; match to protein family HMM PF00496 YP_001457628.1 identified by similarity to SP:P75798; match to protein family HMM PF00528 YP_001457629.1 identified by similarity to SP:P75799; match to protein family HMM PF00528 YP_001457630.1 identified by match to protein family HMM PF00563 YP_001457631.1 yliF; identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001457632.1 NULL; identified by match to protein family HMM PF01381 YP_001457633.1 NULL; identified by match to protein family HMM PF06296 YP_001457634.1 yliG; identified by match to protein family HMM PF00919; match to protein family HMM PF04055; match to protein family HMM TIGR00089; match to protein family HMM TIGR01125 YP_001457635.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_001457636.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_001457637.1 penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_001457638.1 identified by similarity to SP:P0ACK5; match to protein family HMM PF00455; match to protein family HMM PF08220 YP_001457639.1 ybjG; identified by match to protein family HMM PF01569 YP_001457640.1 identified by glimmer YP_001457641.1 identified by match to protein family HMM PF07690 YP_001457642.1 ybjH YP_001457643.1 identified by similarity to SP:P75809; match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_001457644.1 identified by match to protein family HMM PF07690 YP_001457645.1 identified by match to protein family HMM PF00440 YP_001457646.1 identified by match to protein family HMM PF00589 YP_001457647.1 identified by glimmer YP_001457648.1 identified by match to protein family HMM PF07022 YP_001457650.1 identified by match to protein family HMM PF06892 YP_001457651.1 identified by similarity to SP:P62534 YP_001457653.1 identified by match to protein family HMM PF01258; match to protein family HMM TIGR02419 YP_001457654.1 identified by similarity to SP:P21311; match to protein family HMM PF02086; match to protein family HMM TIGR00571 YP_001457655.1 identified by match to protein family HMM PF05840 YP_001457656.1 identified by similarity to GB:CAD09430.1 YP_001457657.1 identified by match to protein family HMM PF06183 YP_001457658.1 identified by glimmer YP_001457659.1 identified by glimmer YP_001457660.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01540 YP_001457661.1 identified by match to protein family HMM PF03237; match to protein family HMM PF06056 YP_001457662.1 identified by match to protein family HMM PF05929 YP_001457663.1 identified by match to protein family HMM PF05125; match to protein family HMM TIGR01551 YP_001457664.1 identified by match to protein family HMM PF05944 YP_001457665.1 identified by match to protein family HMM PF05926 YP_001457666.1 identified by match to protein family HMM PF05489 YP_001457667.1 identified by similarity to GB:AAC45168.1 YP_001457668.1 identified by match to protein family HMM PF00959 YP_001457669.1 identified by similarity to GB:AAN79431.1 YP_001457670.1 identified by similarity to SP:P51770 YP_001457671.1 identified by match to protein family HMM PF06891 YP_001457672.1 identified by match to protein family HMM PF05069; match to protein family HMM TIGR01635 YP_001457673.1 identified by similarity to SP:P31340; match to protein family HMM PF04717; match to protein family HMM TIGR01644 YP_001457674.1 identified by similarity to SP:P51768; match to protein family HMM PF04965 YP_001457675.1 identified by similarity to SP:P51767; match to protein family HMM PF04865 YP_001457676.1 identified by match to protein family HMM TIGR01634 YP_001457677.1 identified by match to protein family HMM PF03406 YP_001457678.1 identified by similarity to SP:P03740; match to protein family HMM PF02413 YP_001457679.1 identified by similarity to SP:P22501; match to protein family HMM PF04984 YP_001457680.1 identified by match to protein family HMM PF04985; match to protein family HMM TIGR01611 YP_001457681.1 identified by match to protein family HMM PF06158 YP_001457683.1 identified by match to protein family HMM TIGR01760 YP_001457684.1 identified by match to protein family HMM PF06995 YP_001457685.1 identified by match to protein family HMM PF05954 YP_001457686.1 identified by match to protein family HMM PF04606 YP_001457687.1 identified by match to protein family HMM PF02080; match to protein family HMM PF06826; match to protein family HMM TIGR01625 YP_001457688.1 ybjM YP_001457689.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_001457690.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function YP_001457691.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds YP_001457692.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 YP_001457694.1 identified by match to protein family HMM PF01547 YP_001457695.1 part of the PotFGHI ATP-dependent putrescine transporter YP_001457696.1 identified by match to protein family HMM PF00528 YP_001457697.1 identified by match to protein family HMM PF00528 YP_001457698.1 ybjO YP_001457699.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_001457700.1 identified by glimmer YP_001457701.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_001457702.1 with ArtPQJI acts to transport arginine across the inner membrane YP_001457703.1 with ArtPMJI transports arginine across the inner membrane YP_001457704.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_001457705.1 With ArtMQJI transports arginine across the inner membrane YP_001457706.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS YP_001457707.1 ybjQ; identified by match to protein family HMM PF01906 YP_001457708.1 identified by similarity to SP:P75820; match to protein family HMM PF01510 YP_001457709.1 ybjS; identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF07993 YP_001457710.1 ybjT; identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF05368 YP_001457711.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine YP_001457712.1 catalyzes the formation of acetate from pyruvate YP_001457713.1 identified by similarity to SP:P75824; match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970 YP_001457714.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_001457715.1 identified by match to protein family HMM PF03956 YP_001457716.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure YP_001457717.1 identified by similarity to GB:ABG68906.1 YP_001457718.1 identified by match to protein family HMM PF04393 YP_001457719.1 confers macrolide resistance via active drug efflux YP_001457720.1 with MacA is involved in the export of macrolide YP_001457721.1 inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible YP_001457722.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001457723.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates YP_001457724.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001457725.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001457726.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001457727.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001457728.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding YP_001457729.1 identified by glimmer YP_001457730.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_001457731.1 DNA-binding membrane protein required for chromosome resolution and partitioning YP_001457732.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_001457733.1 identified by similarity to SP:P0AAZ4; match to protein family HMM PF00004 YP_001457734.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001457735.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_001457736.1 identified by similarity to SP:P18776; match to protein family HMM PF00037; match to protein family HMM TIGR02951 YP_001457737.1 identified by similarity to SP:P18777; match to protein family HMM PF04976 YP_001457738.1 identified by glimmer YP_001457739.1 identified by match to protein family HMM PF07690 YP_001457740.1 identified by match to protein family HMM PF00324 YP_001457741.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001457742.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_001457743.1 identified by similarity to SP:P09373; match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255 YP_001457744.1 identified by match to protein family HMM PF01226; match to protein family HMM TIGR00790 YP_001457745.1 ycaO; identified by similarity to GB:AAP16417.1; match to protein family HMM PF02624; match to protein family HMM TIGR00702 YP_001457746.1 ycaP; identified by match to protein family HMM PF04239 YP_001457747.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_001457748.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001457749.1 ycaL; identified by match to protein family HMM PF01435 YP_001457750.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001457751.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001457752.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001457753.1 involved in the transport of lipid A across the inner membrane YP_001457754.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_001457755.1 ycaQ; identified by match to protein family HMM PF06224 YP_001457756.1 ycaR; identified by similarity to GB:AAX64850.1; match to protein family HMM PF03966 YP_001457757.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001457758.1 ycbJ YP_001457759.1 ycbC; identified by match to protein family HMM PF02698 YP_001457760.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA YP_001457761.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division YP_001457762.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division YP_001457763.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects YP_001457764.1 identified by match to protein family HMM PF01471 YP_001457765.1 ycbK; identified by match to protein family HMM PF05951; match to protein family HMM PF08291; match to protein family HMM TIGR01409 YP_001457766.1 ycbL; identified by match to protein family HMM PF00753 YP_001457767.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001457768.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001457769.1 outer membrane porin F; 1a; Ia; b YP_001457770.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001457771.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_001457772.1 identified by match to protein family HMM PF01433; match to protein family HMM TIGR02414 YP_001457773.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease YP_001457774.1 part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease YP_001457775.1 catalyzes the release of sulfite from alkanesulfonates YP_001457776.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease YP_001457777.1 identified by match to protein family HMM PF02525; match to protein family HMM PF03358 YP_001457778.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001457779.1 identified by similarity to SP:P30130; match to protein family HMM PF00577 YP_001457780.1 identified by match to protein family HMM PF00419 YP_001457781.1 identified by match to protein family HMM PF00419 YP_001457782.1 identified by match to protein family HMM PF00419 YP_001457783.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001457784.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001457785.1 ycbW; identified by match to protein family HMM PF07126 YP_001457786.1 identified by match to protein family HMM PF00111; match to protein family HMM PF03473; match to protein family HMM PF03476 YP_001457787.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_001457788.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_001457789.1 identified by similarity to SP:P43670; match to protein family HMM PF04403; match to protein family HMM TIGR00155 YP_001457790.1 identified by similarity to SP:P43671; match to protein family HMM PF02470 YP_001457791.1 ymbA; identified by match to protein family HMM PF03886 YP_001457792.1 identified by similarity to SP:P22986; match to protein family HMM PF04957 YP_001457793.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_001457795.1 identified by match to protein family HMM PF06303 YP_001457796.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d YP_001457797.1 identified by match to protein family HMM PF03846; match to protein family HMM TIGR00623 YP_001457798.1 yccR; identified by match to protein family HMM PF04993; match to protein family HMM PF04994 YP_001457799.1 yccS; identified by match to protein family HMM PF05976; match to protein family HMM TIGR01666; match to protein family HMM TIGR01667 YP_001457800.1 yccF; identified by match to protein family HMM PF03733 YP_001457801.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand YP_001457802.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_001457803.1 yccT YP_001457804.1 identified by match to protein family HMM PF02629 YP_001457805.1 identified by similarity to SP:P0AB20; match to protein family HMM PF08755; match to protein family HMM TIGR02097 YP_001457806.1 identified by match to protein family HMM PF03602 YP_001457807.1 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs YP_001457808.1 identified by match to protein family HMM PF01027 YP_001457809.1 identified by match to protein family HMM PF01058; match to protein family HMM PF08425; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409 YP_001457810.1 involved in hydrogen cycling during fermentative growth YP_001457811.1 identified by match to protein family HMM PF01292; match to protein family HMM TIGR02125 YP_001457812.1 HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1) YP_001457813.1 involved in processing hydrogenases HyaA and HyaB YP_001457814.1 identified by similarity to SP:P19932; match to protein family HMM PF04809 YP_001457815.1 identified by match to protein family HMM PF01654 YP_001457816.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203 YP_001457817.1 yccB; identified by match to protein family HMM PF08173 YP_001457818.1 identified by similarity to SP:P07102; match to protein family HMM PF00328 YP_001457819.1 yccC; identified by similarity to SP:P38134; match to protein family HMM PF02706 YP_001457820.1 Etk and Etp are a tyrosine kinase-tyrosine phosphatase pair, etp dephosphorylates etk YP_001457821.1 identified by similarity to SP:P0A934; match to protein family HMM PF02563 YP_001457822.1 ymcB; identified by similarity to SP:P75883; match to protein family HMM PF06251 YP_001457823.1 identified by similarity to SP:P75884 YP_001457824.1 identified by similarity to SP:P75885 YP_001457825.1 identified by match to protein family HMM PF00313 YP_001457826.1 identified by match to protein family HMM PF00313 YP_001457828.1 identified by glimmer YP_001457829.1 yccM; identified by match to protein family HMM PF00037 YP_001457830.1 identified by glimmer YP_001457831.1 Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide YP_001457832.1 periplasmic sensory protein associated with the TorRS two-component regulatory system YP_001457833.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes YP_001457834.1 identified by similarity to SP:P33226; match to protein family HMM PF03264; match to protein family HMM TIGR02162 YP_001457835.1 identified by similarity to SP:P33225; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; match to protein family HMM TIGR01409; match to protein family HMM TIGR02164 YP_001457836.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor YP_001457837.1 identified by glimmer YP_001457838.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA YP_001457839.1 functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock YP_001457840.1 NULL; identified by similarity to SP:P36661 YP_001457841.1 identified by glimmer YP_001457842.1 identified by similarity to SP:P19926; match to protein family HMM PF00328 YP_001457843.1 yccJ YP_001457844.1 stationary phase that binds TrpR repressor YP_001457845.1 identified by similarity to GB:BAA35782.1 YP_001457846.1 identified by glimmer YP_001457847.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001457848.1 identified by similarity to SP:P75892; match to protein family HMM PF00860; match to protein family HMM TIGR00801 YP_001457849.1 identified by similarity to SP:P75893; match to protein family HMM PF01613 YP_001457850.1 identified by similarity to SP:P75894; match to protein family HMM PF00881 YP_001457851.1 identified by similarity to SP:P75895; match to protein family HMM PF00561 YP_001457852.1 identified by similarity to SP:P0AFQ5; match to protein family HMM PF01042 YP_001457853.1 identified by similarity to SP:P75897; match to protein family HMM PF00857 YP_001457854.1 identified by similarity to SP:P75898; match to protein family HMM PF00296 YP_001457855.1 identified by similarity to SP:P0ACU2; match to protein family HMM PF00440; match to protein family HMM PF08362 YP_001457856.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein YP_001457857.1 identified by glimmer YP_001457858.1 identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813; match to protein family HMM TIGR02121 YP_001457859.1 identified by match to protein family HMM PF03239; match to protein family HMM TIGR00145 YP_001457860.1 ycdO; identified by match to protein family HMM PF04302 YP_001457861.1 ycdB; identified by match to protein family HMM PF04261; match to protein family HMM TIGR01409; match to protein family HMM TIGR01412; match to protein family HMM TIGR01413 YP_001457862.1 identified by similarity to SP:P0A9K1; match to protein family HMM PF02562 YP_001457863.1 ycdP YP_001457864.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide YP_001457865.1 ycdR; identified by match to protein family HMM PF01522 YP_001457866.1 identified by match to protein family HMM PF03400 YP_001457867.1 identified by match to protein family HMM PF03811 YP_001457868.1 ycdT; identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001457869.1 identified by similarity to GB:AAZ76519.1; match to protein family HMM PF01527 YP_001457870.1 identified by glimmer YP_001457871.1 ycdU YP_001457872.1 identified by glimmer YP_001457873.1 identified by match to protein family HMM PF02826 YP_001457874.1 ycdX; identified by match to protein family HMM PF02811 YP_001457875.1 identified by match to protein family HMM PF06192 YP_001457876.1 ycdZ; identified by match to protein family HMM PF06496 YP_001457877.1 identified by match to protein family HMM PF03783 YP_001457878.1 nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex YP_001457879.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex YP_001457880.1 activates the csgBA and csgDEFG operons involved in biofilm formation YP_001457881.1 identified by glimmer YP_001457882.1 CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface YP_001457883.1 identified by similarity to SP:P28307; match to protein family HMM PF07012 YP_001457884.1 involved in autoagglutination of curliated cells; not involved in production of curli fibers YP_001457885.1 identified by match to protein family HMM PF03400 YP_001457886.1 identified by match to protein family HMM PF03811 YP_001457887.1 ymdA YP_001457888.1 identified by match to protein family HMM PF01661 YP_001457889.1 identified by match to protein family HMM PF00614 YP_001457890.1 required for the transfer of succinyl residues to the glucan backbone YP_001457891.1 identified by glimmer YP_001457892.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_001457893.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_001457894.1 identified by glimmer YP_001457895.1 yceK; identified by match to protein family HMM PF07119 YP_001457897.1 Confers resistance to fosfomycin and deoxycholate YP_001457898.1 identified by glimmer YP_001457899.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_001457900.1 yceA; identified by match to protein family HMM PF00581 YP_001457901.1 identified by similarity to SP:P0A8X2; match to protein family HMM PF04264 YP_001457902.1 identified by match to protein family HMM PF01292 YP_001457903.1 yceO; identified by similarity to RF:NP_460130.1 YP_001457904.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids YP_001457905.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_001457906.1 identified by similarity to SP:P0ABR4; match to protein family HMM PF06183 YP_001457907.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001457908.1 yceB; identified by match to protein family HMM PF07273 YP_001457909.1 cofactor involved in the reduction of disulfides YP_001457910.1 Confers resistance to norfloxacin and enoxacin YP_001457911.1 identified by similarity to SP:P0A948; match to protein family HMM PF00583 YP_001457912.1 yceH; identified by match to protein family HMM PF04337 YP_001457913.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_001457914.1 identified by match to protein family HMM PF03023; match to protein family HMM TIGR01695 YP_001457915.1 identified by match to protein family HMM PF05130 YP_001457916.1 regulates the flagellar specific sigma28 transcription factor YP_001457917.1 required for the assembly of the flagellar basal body P-ring YP_001457918.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella YP_001457919.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_001457920.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_001457921.1 the hook connects flagellar basal body to the flagellar filament YP_001457922.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_001457923.1 makes up the distal portion of the flagellar basal body rod YP_001457924.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_001457925.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001457926.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_001457927.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_001457928.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes YP_001457929.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase YP_001457930.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA YP_001457931.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001457932.1 yceD; identified by match to protein family HMM PF02620 YP_001457933.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001457934.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001457935.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001457936.1 identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128 YP_001457937.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001457938.1 carries the fatty acid chain in fatty acid biosynthesis YP_001457939.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001457940.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate YP_001457941.1 identified by match to protein family HMM PF02618; match to protein family HMM TIGR00247 YP_001457942.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_001457943.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_001457944.1 identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010 YP_001457945.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001457946.1 identified by similarity to SP:P16869; match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783 YP_001457948.1 ycfF; identified by similarity to SP:P0ACE7; match to protein family HMM PF01230 YP_001457949.1 ycfL; identified by match to protein family HMM PF07233 YP_001457950.1 ycfM; identified by match to protein family HMM TIGR02722 YP_001457951.1 catalyzes the phosphorylation of thiamine to thiamine phosphate YP_001457952.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_001457953.1 ycfP; identified by match to protein family HMM PF05728 YP_001457954.1 identified by similarity to SP:P00393; match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF07992 YP_001457955.1 ycfJ; identified by match to protein family HMM PF05433 YP_001457956.1 ycfQ; identified by match to protein family HMM PF00440 YP_001457957.1 ycfR; identified by match to protein family HMM PF07338 YP_001457958.1 identified by match to protein family HMM PF01476; match to protein family HMM PF03734 YP_001457959.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580 YP_001457960.1 ycfT; identified by match to protein family HMM PF01757 YP_001457961.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone YP_001457962.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_001457963.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine YP_001457964.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_001457965.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate YP_001457966.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component YP_001457967.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component YP_001457968.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase YP_001457969.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_001457970.1 identified by match to protein family HMM PF08007 YP_001457971.1 identified by similarity to SP:P23837; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF08918 YP_001457972.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress YP_001457973.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001457974.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_001457975.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001457976.1 identified by match to protein family HMM PF00293 YP_001457977.1 catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA YP_001457978.1 Converts isocitrate to alpha ketoglutarate YP_001457979.1 ycgX; identified by match to protein family HMM PF07166 YP_001457980.1 identified by similarity to SP:P33358; match to protein family HMM PF00376 YP_001457981.1 ycgF; identified by match to protein family HMM PF00563; match to protein family HMM PF04940 YP_001457982.1 identified by similarity to GB:AAP17067.1; match to protein family HMM PF00665 YP_001457983.1 identified by match to protein family HMM PF01527 YP_001457984.1 ymgB YP_001457985.1 ymgC YP_001457986.1 identified by match to protein family HMM PF00563 YP_001457987.1 ymgF YP_001457988.1 identified by glimmer YP_001457989.1 identified by glimmer YP_001457990.1 ymgD; identified by glimmer YP_001457991.1 identified by similarity to GB:ABB13223.1 YP_001457992.1 identified by glimmer YP_001457993.1 identified by glimmer YP_001457994.1 identified by glimmer YP_001457995.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_001457996.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums YP_001457997.1 blocks the formation of polar Z-ring septums YP_001457998.1 ycgJ; identified by match to protein family HMM PF05666 YP_001457999.1 ycgK; identified by match to protein family HMM PF04151 YP_001458000.1 ycgL; identified by match to protein family HMM PF05166 YP_001458001.1 identified by match to protein family HMM PF01557 YP_001458002.1 ycgN; identified by similarity to GB:ABB61366.1; match to protein family HMM PF03692 YP_001458003.1 identified by glimmer YP_001458004.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization YP_001458005.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization YP_001458006.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_001458007.1 involved in regulation of intracellular pH under alkaline conditions YP_001458008.1 Multifunctional regulator of fatty acid metabolism YP_001458009.1 identified by match to protein family HMM PF04293 YP_001458010.1 catalyzes the oxidative deamination of D-amino acids YP_001458011.1 catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA YP_001458012.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_001458013.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine YP_001458014.1 identified by similarity to SP:P76009; match to protein family HMM PF01464 YP_001458015.1 identified by match to protein family HMM PF07238; match to protein family HMM PF07317 YP_001458016.1 identified by match to protein family HMM PF04226 YP_001458017.1 ycgY; identified by similarity to GB:ABB66472.1 YP_001458018.1 periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell YP_001458020.1 phosphotransferaese subunit; phosphorylates dihydroxyacetone YP_001458021.1 with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone YP_001458022.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase YP_001458023.1 Positively regulates the dhaKLM operon from a sigma-70 promoter YP_001458024.1 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414 YP_001458025.1 identified by similarity to GB:AAZ88642.1 YP_001458026.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001458027.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001458028.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function YP_001458029.1 role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport YP_001458030.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001458031.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_001458032.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_001458033.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001458034.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001458035.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB YP_001458036.1 ychQ; identified by match to protein family HMM PF04247 YP_001458037.1 ychA; identified by similarity to SP:P20101 YP_001458038.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001458039.1 identified by glimmer YP_001458040.1 identified by similarity to GB:AAZ88629.1 YP_001458041.1 identified by similarity to GB:AAZ88629.1 YP_001458042.1 identified by similarity to SP:P31801; match to protein family HMM PF01699; match to protein family HMM TIGR00846 YP_001458043.1 in Escherichia coli this protein ly regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions YP_001458044.1 identified by match to protein family HMM PF04752 YP_001458045.1 ychN; identified by match to protein family HMM PF02635 YP_001458046.1 identified by glimmer YP_001458048.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase YP_001458049.1 identified by similarity to SP:P10956; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF07730 YP_001458050.1 identified by glimmer YP_001458051.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00886 YP_001458052.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580 YP_001458053.1 identified by similarity to SP:P11349; match to protein family HMM PF00037; match to protein family HMM TIGR01660 YP_001458054.1 identified by similarity to SP:P0AF26; match to protein family HMM PF02613; match to protein family HMM TIGR00684 YP_001458055.1 identified by similarity to SP:P11350; match to protein family HMM PF02665; match to protein family HMM TIGR00351 YP_001458056.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001458057.1 ychJ; identified by match to protein family HMM PF02810 YP_001458058.1 ychK; identified by match to protein family HMM PF01734 YP_001458059.1 identified by match to protein family HMM PF00072 YP_001458060.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_001458061.1 identified by match to protein family HMM PF00816 YP_001458062.1 identified by glimmer YP_001458063.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_001458064.1 identified by similarity to SP:P0A9Q7; match to protein family HMM PF00171; match to protein family HMM PF00465 YP_001458065.1 identified by match to protein family HMM PF01914; match to protein family HMM TIGR00427 YP_001458066.1 identified by match to protein family HMM PF00496 YP_001458067.1 identified by match to protein family HMM PF00528 YP_001458068.1 identified by match to protein family HMM PF00528 YP_001458069.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_001458070.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_001458071.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein YP_001458072.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_001458073.1 identified by similarity to SP:P31069; match to protein family HMM PF02254; match to protein family HMM PF07885 YP_001458074.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_001458075.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins YP_001458076.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase of proteins YP_001458077.1 Involved in cell division; probably involved in intracellular septation YP_001458078.1 yciC; identified by match to protein family HMM PF06790 YP_001458079.1 receptor for colicin S4 YP_001458080.1 yciE; identified by match to protein family HMM PF05974 YP_001458081.1 identified by similarity to SP:P21362; match to protein family HMM PF05974 YP_001458082.1 identified by similarity to GB:AAX64977.1 YP_001458083.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001458084.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001458085.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_001458086.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis YP_001458087.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_001458089.1 trpH protein; identified by match to protein family HMM PF02811 YP_001458090.1 identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057 YP_001458091.1 yciQ YP_001458092.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA YP_001458093.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_001458094.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_001458095.1 SohB; periplasmic protein; member of the peptidase S49 family YP_001458096.1 identified by similarity to GB:CAD08416.1 YP_001458097.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001458098.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_001458099.1 identified by match to protein family HMM PF03811 YP_001458100.1 identified by match to protein family HMM PF03400 YP_001458101.1 Catalyzes the conversion of citrate to isocitrate YP_001458102.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_001458103.1 identified by similarity to SP:P0A924; match to protein family HMM PF01569 YP_001458104.1 yciS; identified by match to protein family HMM PF06305 YP_001458105.1 identified by match to protein family HMM PF07719 YP_001458106.1 identified by glimmer YP_001458107.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001458108.1 involved in start site selection during the initiation of translation YP_001458109.1 identified by similarity to SP:P0ADA7 YP_001458110.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_001458112.1 c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP YP_001458113.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction YP_001458115.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_001458116.1 identified by glimmer YP_001458117.1 ycjD; identified by similarity to GB:ABB66373.1; match to protein family HMM PF04480 YP_001458118.1 identified by similarity to SP:P36638; match to protein family HMM PF00005 YP_001458119.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_001458120.1 identified by match to protein family HMM PF00528 YP_001458121.1 identified by match to protein family HMM PF00528 YP_001458122.1 identified by match to protein family HMM PF00496 YP_001458123.1 ymjA YP_001458124.1 identified by glimmer YP_001458125.1 identified by match to protein family HMM PF00324 YP_001458126.1 identified by similarity to SP:P78061; match to protein family HMM PF00120 YP_001458127.1 catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate YP_001458128.1 regulates genes involved in putrescine degradation YP_001458129.1 catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation YP_001458130.1 identified by similarity to SP:P37906; match to protein family HMM PF01266 YP_001458131.1 putrescine-inducible GABA aminotransferase; catalyzes the formation of glutamate and succinate semialdehyde from 4-aminobutyrate and 2-oxoglutarate YP_001458132.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor YP_001458133.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF YP_001458134.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding YP_001458135.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock YP_001458136.1 identified by match to protein family HMM TIGR02979 YP_001458137.1 rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide YP_001458138.1 identified by match to protein family HMM PF00128 YP_001458139.1 identified by match to protein family HMM PF01547 YP_001458140.1 identified by match to protein family HMM PF00528 YP_001458141.1 identified by match to protein family HMM PF00528 YP_001458142.1 identified by match to protein family HMM PF00107 YP_001458143.1 ycjR; identified by match to protein family HMM PF01261 YP_001458144.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_001458145.1 ycjT; identified by match to protein family HMM PF03632; match to protein family HMM PF03633; match to protein family HMM PF03636 YP_001458146.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01990; match to protein family HMM TIGR02009 YP_001458147.1 identified by match to protein family HMM PF00005; match to protein family HMM PF03459; match to protein family HMM PF08402 YP_001458148.1 identified by match to protein family HMM TIGR03304 YP_001458149.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001458150.1 identified by match to protein family HMM PF04317 YP_001458151.1 ycjF; identified by match to protein family HMM PF05128; match to protein family HMM TIGR01620 YP_001458152.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids YP_001458153.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_001458154.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_001458155.1 identified by match to protein family HMM PF00246 YP_001458156.1 ycjY YP_001458157.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001458158.1 identified by glimmer YP_001458159.1 identified by match to protein family HMM PF00496 YP_001458160.1 identified by match to protein family HMM PF00924 YP_001458161.1 ynaJ YP_001458162.1 with UspC and UspD is involved in resistance to UV irradiation YP_001458163.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_001458164.1 identified by similarity to SP:P0AFH0; match to protein family HMM PF01035; match to protein family HMM PF02870; match to protein family HMM TIGR00589 YP_001458165.1 identified by similarity to SP:P46133; match to protein family HMM PF03806; match to protein family HMM TIGR00819 YP_001458166.1 identified by similarity to SP:P76052; match to protein family HMM PF01546; match to protein family HMM TIGR01891 YP_001458167.1 identified by similarity to SP:P77357; match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891 YP_001458168.1 identified by glimmer YP_001458169.1 identified by similarity to SP:P77744; match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001458170.1 identified by match to protein family HMM PF01713 YP_001458171.1 identified by match to protein family HMM PF00990; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254 YP_001458172.1 ydaN; identified by match to protein family HMM PF01544 YP_001458173.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_001458174.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_001458175.1 identified by similarity to SP:P37903; match to protein family HMM PF00582 YP_001458176.1 identified by similarity to SP:P77747; match to protein family HMM PF00267 YP_001458177.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176 YP_001458179.1 identified by similarity to SP:P52644; match to protein family HMM PF03724 YP_001458180.1 identified by similarity to SP:P52643; match to protein family HMM PF00389; match to protein family HMM PF02826 YP_001458181.1 ydbH; identified by similarity to SP:P52645 YP_001458182.1 ynbE YP_001458183.1 ydbL; identified by similarity to GB:AAN80294.1; match to protein family HMM PF07027 YP_001458184.1 activator of genes involved in phenylacetic acid catabolism YP_001458185.1 identified by similarity to SP:P80668; match to protein family HMM PF00171 YP_001458186.1 catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine YP_001458187.1 catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA YP_001458188.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA YP_001458189.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation YP_001458190.1 identified by match to protein family HMM PF05138; match to protein family HMM TIGR02158 YP_001458191.1 identified by match to protein family HMM PF01883; match to protein family HMM TIGR02159 YP_001458192.1 identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM TIGR02160 YP_001458193.1 identified by match to protein family HMM PF00378 YP_001458194.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001458195.1 converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation YP_001458196.1 identified by similarity to SP:P76084; match to protein family HMM PF03061; match to protein family HMM TIGR00369; match to protein family HMM TIGR02286 YP_001458197.1 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA YP_001458198.1 identified by match to protein family HMM TIGR02155 YP_001458199.1 identified by similarity to SP:P76086; match to protein family HMM PF07848; match to protein family HMM PF08223; match to protein family HMM TIGR02277 YP_001458200.1 identified by match to protein family HMM PF00132; match to protein family HMM TIGR02287 YP_001458201.1 identified by match to protein family HMM PF03797 YP_001458202.1 identified by match to protein family HMM PF00248 YP_001458203.1 ydbD; identified by similarity to SP:P25907 YP_001458204.1 ynbA; identified by match to protein family HMM PF01066 YP_001458205.1 identified by match to protein family HMM PF01148 YP_001458206.1 ynbC; identified by similarity to SP:P76092 YP_001458207.1 identified by match to protein family HMM PF00782; match to protein family HMM PF01569 YP_001458208.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_001458209.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain YP_001458210.1 ydcF; identified by match to protein family HMM PF02698 YP_001458211.1 NAD-linked YP_001458212.1 identified by similarity to SP:P33898; match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534 YP_001458213.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm YP_001458214.1 ydcA YP_001458215.1 identified by glimmer YP_001458216.1 identified by similarity to SP:P05704; match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203 YP_001458217.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001458218.1 ydcJ; identified by similarity to SP:P15747; match to protein family HMM PF07063 YP_001458219.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans YP_001458220.1 ydcH; identified by similarity to GB:CAE37095.1; match to protein family HMM PF04325 YP_001458221.1 identified by similarity to SP:P13857; match to protein family HMM PF00583 YP_001458222.1 ydcK; identified by similarity to SP:P15644 YP_001458223.1 identified by similarity to SP:P25396; match to protein family HMM PF03595; match to protein family HMM TIGR00816 YP_001458224.1 with TehA confers resistance to tellurite YP_001458225.1 identified by glimmer YP_001458226.1 ydcL YP_001458227.1 identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766 YP_001458228.1 identified by match to protein family HMM PF00860; match to protein family HMM PF03594; match to protein family HMM TIGR00843 YP_001458229.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883 YP_001458230.1 identified by match to protein family HMM PF01136 YP_001458231.1 yncJ YP_001458232.1 identified by glimmer YP_001458233.1 ydcQ; identified by match to protein family HMM PF01381; match to protein family HMM PF03681 YP_001458234.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_001458235.1 identified by match to protein family HMM PF01547 YP_001458236.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08402 YP_001458237.1 identified by match to protein family HMM PF00528 YP_001458238.1 identified by match to protein family HMM PF00528 YP_001458239.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation YP_001458240.1 identified by match to protein family HMM PF03811 YP_001458241.1 identified by match to protein family HMM PF03400 YP_001458242.1 NULL YP_001458244.1 identified by match to protein family HMM PF04657 YP_001458245.1 identified by match to protein family HMM PF00583 YP_001458246.1 identified by match to protein family HMM PF00107 YP_001458247.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_001458248.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR03304 YP_001458249.1 identified by glimmer YP_001458251.1 identified by match to protein family HMM PF00324 YP_001458253.1 identified by glimmer YP_001458254.1 identified by match to protein family HMM PF01609 YP_001458255.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown YP_001458256.1 identified by similarity to SP:P76121 YP_001458257.1 identified by match to protein family HMM PF00797 YP_001458258.1 yddE; identified by match to protein family HMM PF02567; match to protein family HMM TIGR00654 YP_001458259.1 identified by similarity to SP:P11350; match to protein family HMM PF02665; match to protein family HMM TIGR00351 YP_001458260.1 identified by similarity to SP:P19317; match to protein family HMM PF02613; match to protein family HMM TIGR00684 YP_001458261.1 identified by similarity to SP:P19318; match to protein family HMM TIGR01660 YP_001458262.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580 YP_001458263.1 identified by similarity to SP:P37758; match to protein family HMM PF07690; match to protein family HMM TIGR00886 YP_001458264.1 identified by similarity to SP:P76123 YP_001458266.1 yddG; identified by match to protein family HMM PF00892 YP_001458267.1 Selenoprotein. identified by similarity to SP:P24183; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR01553 YP_001458268.1 identified by similarity to SP:P0AAJ3; match to protein family HMM PF00037; match to protein family HMM PF09163; match to protein family HMM TIGR01582 YP_001458269.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase YP_001458270.1 identified by glimmer YP_001458271.1 identified by match to protein family HMM PF01381; match to protein family HMM TIGR02607 YP_001458272.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs YP_001458273.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_001458274.1 protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase YP_001458275.1 identified by similarity to SP:P76127 YP_001458276.1 identified by match to protein family HMM PF02566 YP_001458277.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_001458278.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_001458279.1 identified by similarity to SP:P77463; match to protein family HMM PF00528 YP_001458280.1 identified by similarity to SP:P77308; match to protein family HMM PF00528 YP_001458281.1 identified by similarity to SP:P76128; match to protein family HMM PF00496 YP_001458282.1 catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis YP_001458283.1 heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate YP_001458284.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001458285.1 yddW; identified by match to protein family HMM PF02638 YP_001458286.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR00910 YP_001458287.1 identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788 YP_001458288.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193 YP_001458289.1 yddB; identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR03304 YP_001458290.1 yddA; identified by match to protein family HMM PF00005; match to protein family HMM PF05992 YP_001458291.1 ydeM; identified by match to protein family HMM PF04055 YP_001458292.1 identified by match to protein family HMM PF00884 YP_001458293.1 regulates the cellular response to acid resistance YP_001458294.1 in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase YP_001458295.1 identified by similarity to SP:P08191; match to protein family HMM PF00419; match to protein family HMM PF09160 YP_001458296.1 identified by similarity to SP:P08190; match to protein family HMM PF00419 YP_001458297.1 identified by match to protein family HMM PF00419 YP_001458298.1 identified by match to protein family HMM PF00577 YP_001458299.1 identified by similarity to SP:P23874; match to protein family HMM PF07804; match to protein family HMM PF07805; match to protein family HMM TIGR03071 YP_001458300.1 identified by similarity to SP:P23873; match to protein family HMM PF01381 YP_001458301.1 identified by similarity to SP:P77432; match to protein family HMM PF00370; match to protein family HMM PF02782 YP_001458302.1 identified by similarity to SP:P76141; match to protein family HMM PF04198 YP_001458303.1 identified by similarity to SP:P77257; match to protein family HMM PF00005 YP_001458304.1 identified by similarity to SP:P77672; match to protein family HMM PF02653 YP_001458305.1 identified by similarity to SP:P0AFS1; match to protein family HMM PF02653 YP_001458306.1 identified by similarity to SP:P76142 YP_001458307.1 identified by similarity to SP:P76143; match to protein family HMM PF01791 YP_001458308.1 yneC; identified by similarity to SP:P64461; match to protein family HMM PF03992 YP_001458309.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate YP_001458310.1 yneE; identified by match to protein family HMM PF05249 YP_001458311.1 catalyzes the formation of D-tagaturonate from D-altronate YP_001458312.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001458313.1 yneG; identified by similarity to GB:AAN80403.1 YP_001458314.1 catalyzes the formation of glutamate from glutamine YP_001458315.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase YP_001458316.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001458317.1 yneK; identified by similarity to GB:AAP17050.1 YP_001458318.1 identified by similarity to SP:Q9S3J9; match to protein family HMM PF07690 YP_001458319.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function YP_001458320.1 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes YP_001458321.1 converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism YP_001458322.1 identified by match to protein family HMM PF02255 YP_001458323.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR00410 YP_001458324.1 identified by match to protein family HMM PF02302 YP_001458325.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_001458326.1 identified by match to protein family HMM PF00892; match to protein family HMM PF03151 YP_001458327.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters YP_001458328.1 identified by similarity to GB:AAV77284.1 YP_001458329.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001458330.1 ydeI; identified by match to protein family HMM PF04076; match to protein family HMM TIGR00156 YP_001458331.1 ydeJ; identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199 YP_001458332.1 identified by similarity to SP:P24171; match to protein family HMM PF01432 YP_001458333.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine YP_001458334.1 ydfH; identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_001458335.1 identified by glimmer YP_001458336.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_001458337.1 identified by similarity to SP:P77228; match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_001458338.1 ydfK; identified by glimmer YP_001458339.1 identified by match to protein family HMM PF00239; match to protein family HMM PF02796 YP_001458340.1 identified by similarity to SP:P03740 YP_001458341.1 phage protein-like; identified by match to protein family HMM PF08400 YP_001458342.1 identified by match to protein family HMM PF06316; match to protein family HMM TIGR03304 YP_001458343.1 identified by match to protein family HMM PF00041; match to protein family HMM PF09327 YP_001458344.1 phage protein DUF1441 YP_001458345.1 identified by match to protein family HMM PF08178 YP_001458346.1 identified by match to protein family HMM PF00313 YP_001458348.1 identified by match to protein family HMM PF00959 YP_001458349.1 identified by similarity to GB:AAP15758.1; match to protein family HMM PF07041 YP_001458350.1 identified by match to protein family HMM PF04971 YP_001458351.1 identified by match to protein family HMM PF00165 YP_001458352.1 DUF523 pathogenicity island protein-like; identified by match to protein family HMM PF04463; match to protein family HMM PF08349 YP_001458353.1 identified by similarity to SP:Q47274; match to protein family HMM PF06530 YP_001458354.1 ydfA YP_001458355.1 identified by match to protein family HMM PF03400 YP_001458356.1 identified by match to protein family HMM PF03811 YP_001458357.1 identified by similarity to SP:P38105; match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001458358.1 identified by similarity to SP:P38104; match to protein family HMM PF01188; match to protein family HMM PF02746 YP_001458359.1 identified by match to protein family HMM PF02694 YP_001458360.1 identified by match to protein family HMM PF06932 YP_001458361.1 identified by similarity to SP:P0A951; match to protein family HMM PF00583 YP_001458362.1 ynfC; identified by match to protein family HMM PF06788 YP_001458363.1 identified by match to protein family HMM PF06649 YP_001458364.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_001458365.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_001458366.1 identified by similarity to SP:P18776; match to protein family HMM PF00037; match to protein family HMM TIGR02951 YP_001458367.1 identified by match to protein family HMM PF04976 YP_001458368.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane YP_001458369.1 identified by glimmer YP_001458370.1 identified by match to protein family HMM PF00654 YP_001458371.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_001458372.1 identified by similarity to SP:P50456; match to protein family HMM PF00480 YP_001458373.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001458374.1 identified by match to protein family HMM PF07690 YP_001458375.1 required for growth and survival under moderately acid conditions YP_001458376.1 identified by match to protein family HMM PF00089 YP_001458377.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS YP_001458378.1 with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS YP_001458379.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes YP_001458380.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme YP_001458381.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_001458382.1 identified by glimmer YP_001458383.1 identified by match to protein family HMM PF07338 YP_001458384.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR00905 YP_001458385.1 identified by match to protein family HMM PF00106 YP_001458386.1 ydgC; identified by match to protein family HMM PF06942 YP_001458387.1 response regulator in two-component regulatory system with RstB YP_001458388.1 identified by similarity to SP:P18392; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_001458389.1 binds to DNA replication terminator sequences to prevent passage of replication forks YP_001458390.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_001458391.1 identified by similarity to SP:P0AC33; match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723 YP_001458392.1 identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218 YP_001458393.1 ydgA; identified by match to protein family HMM PF06097 YP_001458394.1 identified by similarity to SP:Q47706 YP_001458395.1 identified by similarity to SP:P30868; match to protein family HMM PF07690; match to protein family HMM TIGR00792 YP_001458396.1 identified by similarity to SP:P05804; match to protein family HMM PF00703; match to protein family HMM PF02836; match to protein family HMM PF02837 YP_001458397.1 identified by match to protein family HMM PF00440 YP_001458398.1 Acts on the hydroxyl group at position 7 of the steroid frame YP_001458399.1 regulates malXY which are involved in maltose-glucose transport YP_001458400.1 phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site YP_001458401.1 identified by similarity to SP:P23256; match to protein family HMM PF00155 YP_001458402.1 catalyzes the formation of inosine from adenosine YP_001458403.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894 YP_001458404.1 identified by similarity to SP:P56976 YP_001458405.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes YP_001458407.1 identified by match to protein family HMM PF02508; match to protein family HMM TIGR01943 YP_001458408.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001458409.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001458410.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_001458411.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_001458412.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_001458413.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines YP_001458414.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation YP_001458415.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_001458416.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_001458417.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001458418.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_001458419.1 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme YP_001458420.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_001458421.1 identified by similarity to SP:P0A1X0; match to protein family HMM PF05433 YP_001458422.1 Transcription regulator that can both activate or repress expression YP_001458423.1 identified by glimmer YP_001458424.1 identified by match to protein family HMM PF07869 YP_001458425.1 identified by match to protein family HMM PF00529 YP_001458426.1 NULL; identified by match to protein family HMM PF04632 YP_001458427.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water YP_001458428.1 NULL; identified by similarity to SP:P76187; match to protein family HMM PF00248 YP_001458429.1 identified by glimmer YP_001458430.1 identified by match to protein family HMM PF00440 YP_001458431.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide YP_001458432.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione YP_001458433.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_001458434.1 identified by glimmer YP_001458435.1 similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases; longest known protein in E. coli YP_001458436.1 identified by similarity to SP:P0AC69; match to protein family HMM PF00462; match to protein family HMM TIGR00365 YP_001458437.1 identified by glimmer YP_001458438.1 identified by match to protein family HMM PF00877 YP_001458439.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals YP_001458440.1 identified by match to protein family HMM PF07690 YP_001458441.1 identified by glimmer YP_001458442.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers YP_001458443.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001458444.1 uncharacterized member of the major facilitator superfamily (MFS) YP_001458445.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_001458446.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001458447.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_001458448.1 ydhQ YP_001458449.1 identified by glimmer YP_001458450.1 identified by similarity to SP:P0ACX4; match to protein family HMM PF08803 YP_001458452.1 identified by similarity to GB:AAN80523.1 YP_001458453.1 ydhU; identified by match to protein family HMM PF01292 YP_001458454.1 identified by match to protein family HMM PF00037 YP_001458455.1 identified by similarity to GB:AAZ88187.1 YP_001458456.1 identified by match to protein family HMM PF01314; match to protein family HMM PF02730 YP_001458457.1 identified by match to protein family HMM PF00037 YP_001458459.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001458460.1 identified by similarity to SP:P69776; match to protein family HMM PF04728 YP_001458461.1 identified by match to protein family HMM PF01476; match to protein family HMM PF03734 YP_001458462.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine YP_001458463.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine YP_001458464.1 with SufBC activates cysteine desulfurase SufS YP_001458465.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE YP_001458466.1 with SufCD activates cysteine desulfurase SufS YP_001458467.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein YP_001458468.1 identified by similarity to SP:P64478 YP_001458469.1 identified by similarity to SP:P77781; match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_001458470.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913 YP_001458471.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function YP_001458472.1 identified by similarity to GB:AAZ88169.1; match to protein family HMM PF08965 YP_001458473.1 identified by match to protein family HMM PF07690 YP_001458474.1 identified by match to protein family HMM PF07690 YP_001458475.1 YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate YP_001458476.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis YP_001458477.1 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain YP_001458478.1 identified by match to protein family HMM PF03400 YP_001458479.1 identified by match to protein family HMM PF03811 YP_001458480.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001458481.1 identified by glimmer YP_001458482.1 ydiA; identified by similarity to SP:Q8ZDY4; match to protein family HMM PF03618 YP_001458483.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_001458484.1 ydiE; identified by similarity to GB:ABB66046.1 YP_001458485.1 identified by similarity to SP:Q8Z6I8; match to protein family HMM PF02696 YP_001458486.1 ydiV; identified by similarity to GB:ABB61913.1 YP_001458487.1 identified by match to protein family HMM PF00877 YP_001458488.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell YP_001458489.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane YP_001458490.1 with BtuD and BtuF transports vitamin B12 into the cell YP_001458491.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001458492.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001458493.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001458494.1 identified by glimmer YP_001458496.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001458497.1 identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001 YP_001458498.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_001458499.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001458500.1 identified by match to protein family HMM PF04338 YP_001458501.1 identified by similarity to SP:P06999; match to protein family HMM PF00294; match to protein family HMM TIGR03168 YP_001458502.1 identified by similarity to SP:P64479 YP_001458503.1 identified by match to protein family HMM PF01636; match to protein family HMM PF03881 YP_001458504.1 yniB; identified by similarity to GB:AAZ88138.1 YP_001458505.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate YP_001458506.1 ydjM; identified by match to protein family HMM PF04307 YP_001458507.1 identified by match to protein family HMM PF00375 YP_001458508.1 ydjO; identified by similarity to GB:AAN43089.1 YP_001458509.1 identified by similarity to SP:P0AE60 YP_001458510.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide YP_001458511.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001458512.1 identified by similarity to GB:BAB92994.1; match to protein family HMM PF04794 YP_001458513.1 identified by similarity to SP:P17411; match to protein family HMM PF02056 YP_001458514.1 represses the celABCDF-ydjC operon involved in carbon uptake YP_001458515.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport YP_001458516.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport YP_001458517.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein YP_001458518.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001458519.1 3' incision activity; acts with UvrC YP_001458520.1 ydjR; identified by match to protein family HMM PF05962 YP_001458521.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP YP_001458522.1 identified by glimmer YP_001458523.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_001458524.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_001458525.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_001458526.1 identified by match to protein family HMM PF04958; match to protein family HMM TIGR03244 YP_001458527.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate YP_001458528.1 identified by glimmer YP_001458529.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_001458530.1 identified by match to protein family HMM PF09335 YP_001458531.1 ydjY; identified by similarity to GB:AAZ88114.1 YP_001458532.1 ydjZ; identified by similarity to SP:P76221; match to protein family HMM PF09335 YP_001458533.1 ynjA; identified by match to protein family HMM PF02627 YP_001458534.1 ynjB YP_001458536.1 identified by match to protein family HMM PF00005 YP_001458538.1 identified by match to protein family HMM PF01066 YP_001458539.1 identified by similarity to SP:P77788; match to protein family HMM PF00293 YP_001458540.1 ynjH; identified by match to protein family HMM PF07383 YP_001458541.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_001458542.1 ynjI; identified by similarity to GB:AAN43058.1 YP_001458543.1 decatenates replicating daughter chromosomes YP_001458544.1 catalyzes the formation of selenophosphate from selenide and ATP YP_001458545.1 ydjA; identified by match to protein family HMM PF00881 YP_001458546.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane YP_001458547.1 converts asparagine to aspartate and ammonia YP_001458548.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide YP_001458549.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_001458550.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_001458551.1 identified by match to protein family HMM PF00248 YP_001458552.1 identified by match to protein family HMM PF00294 YP_001458553.1 identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167 YP_001458554.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_001458555.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001458556.1 NULL; identified by match to protein family HMM PF07023 YP_001458557.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_001458558.1 identified by similarity to SP:P0A9B2; match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534 YP_001458559.1 yeaD; identified by match to protein family HMM PF01263 YP_001458560.1 identified by similarity to SP:P76234; match to protein family HMM PF00248 YP_001458561.1 yeaF; identified by similarity to SP:P0A908; match to protein family HMM PF06629 YP_001458562.1 identified by glimmer YP_001458563.1 yeaG; identified by match to protein family HMM PF06798; match to protein family HMM PF08298 YP_001458564.1 yeaH; identified by match to protein family HMM PF04285 YP_001458565.1 yeaI; identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001458566.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001458567.1 identified by match to protein family HMM PF04073 YP_001458568.1 identified by similarity to GB:AAZ88084.1 YP_001458569.1 yeaL; identified by similarity to SP:P0ACY8; match to protein family HMM PF04284 YP_001458570.1 identified by match to protein family HMM PF00165 YP_001458571.1 identified by similarity to SP:P76242; match to protein family HMM PF07690; match to protein family HMM TIGR00896 YP_001458572.1 yeaO; identified by match to protein family HMM PF04343 YP_001458573.1 yoaF; identified by match to protein family HMM PF03891 YP_001458574.1 identified by match to protein family HMM PF00990; match to protein family HMM PF01590; match to protein family HMM TIGR00254 YP_001458575.1 identified by glimmer YP_001458576.1 identified by match to protein family HMM PF04226 YP_001458577.1 identified by glimmer YP_001458578.1 yoaG; identified by similarity to GB:CAG74382.1; match to protein family HMM PF08956 YP_001458579.1 yeaR; identified by match to protein family HMM PF09313 YP_001458580.1 yeaS; identified by match to protein family HMM PF01810 YP_001458581.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001458582.1 identified by similarity to SP:Q51945; match to protein family HMM PF00180; match to protein family HMM TIGR02089 YP_001458583.1 member of the betaine, carnitine, choline transporter (BCCT) family; unknown function YP_001458584.1 identified by match to protein family HMM PF00355 YP_001458585.1 identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970 YP_001458586.1 identified by match to protein family HMM PF00570; match to protein family HMM PF01612; match to protein family HMM TIGR01388 YP_001458587.1 Activates fatty acids by binding to coenzyme A YP_001458588.1 identified by similarity to SP:P37194; match to protein family HMM PF03843; match to protein family HMM TIGR00752 YP_001458589.1 yeaZ; identified by match to protein family HMM PF00814 YP_001458591.1 identified by match to protein family HMM PF01042 YP_001458592.1 identified by similarity to SP:P64492; match to protein family HMM PF08986 YP_001458593.1 identified by match to protein family HMM PF03811 YP_001458594.1 identified by match to protein family HMM PF03400 YP_001458595.1 identified by glimmer YP_001458596.1 identified by similarity to SP:P05041; match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553 YP_001458597.1 identified by match to protein family HMM PF00293 YP_001458598.1 identified by similarity to SP:P16095; match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720 YP_001458599.1 identified by match to protein family HMM PF00563 YP_001458600.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471; match to protein family HMM PF03741 YP_001458601.1 identified by match to protein family HMM PF03610; match to protein family HMM PF03830; match to protein family HMM TIGR00824; match to protein family HMM TIGR00854 YP_001458602.1 identified by match to protein family HMM PF03609; match to protein family HMM TIGR00822 YP_001458603.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel YP_001458604.1 identified by similarity to SP:Q8ZP01; match to protein family HMM PF06173 YP_001458605.1 membrane protein YebN YP_001458606.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth YP_001458607.1 identified by similarity to SP:P0A9Y6; match to protein family HMM PF00313 YP_001458608.1 identified by similarity to SP:P64511 YP_001458609.1 identified by similarity to SP:P64499 YP_001458611.1 NULL; identified by similarity to GB:ABB62074.1 YP_001458612.1 identified by similarity to SP:P76268; match to protein family HMM PF01614; match to protein family HMM PF09339 YP_001458613.1 identified by match to protein family HMM PF07690 YP_001458614.1 metalloprotease YP_001458615.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_001458616.1 affects solute and DNA transport through an unknown mechanism YP_001458617.1 identified by match to protein family HMM PF01590 YP_001458618.1 identified by match to protein family HMM PF04403; match to protein family HMM TIGR00155 YP_001458619.1 identified by similarity to SP:P76272; match to protein family HMM PF02470 YP_001458620.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_001458621.1 identified by match to protein family HMM PF07351 YP_001458622.1 identified by match to protein family HMM PF07358 YP_001458623.1 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins YP_001458624.1 identified by similarity to GB:ABB61282.1 YP_001458625.1 identified by match to protein family HMM PF05425 YP_001458626.1 identified by match to protein family HMM PF04234 YP_001458627.1 identified by similarity to SP:P0ABT1; match to protein family HMM PF06440 YP_001458628.1 NULL; identified by match to protein family HMM PF00795 YP_001458629.1 3'-5' exonuclease activity on single or double-strand DNA YP_001458630.1 PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues YP_001458631.1 identified by similarity to GB:AAN80716.1 YP_001458632.1 identified by glimmer YP_001458633.1 secreted protein; unknown function YP_001458634.1 identified by similarity to SP:P0ACY9; match to protein family HMM PF07130 YP_001458635.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_001458636.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_001458637.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_001458638.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001458639.1 identified by similarity to GB:AAN80723.1 YP_001458640.1 Represses the expression of the zwf, eda, glp and gap YP_001458641.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001458642.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_001458643.1 yebA; identified by match to protein family HMM PF01476; match to protein family HMM PF01551; match to protein family HMM PF04225; match to protein family HMM PF08525 YP_001458644.1 involved in transport of zinc(II) with ZnuA and C YP_001458645.1 involved in transport of zinc(II) with ZnuA and C YP_001458646.1 involved in transport of zinc(II) with ZnuA and C YP_001458647.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001458648.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001458649.1 yebB; identified by match to protein family HMM PF06520 YP_001458650.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001458651.1 yebC; identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033 YP_001458652.1 converts dATP to dAMP and pyrophosphate YP_001458653.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001458654.1 identified by glimmer YP_001458655.1 yecD; identified by match to protein family HMM PF00857 YP_001458656.1 identified by similarity to SP:P37348; match to protein family HMM PF01904 YP_001458657.1 yecN; identified by similarity to SP:P64515 YP_001458658.1 yecO; identified by match to protein family HMM PF08241; match to protein family HMM PF08242; match to protein family HMM TIGR00740 YP_001458659.1 identified by match to protein family HMM PF08003; match to protein family HMM PF08241; match to protein family HMM TIGR00452 YP_001458660.1 identified by glimmer YP_001458661.1 identified by similarity to SP:P46923; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; match to protein family HMM TIGR01409 YP_001458662.1 identified by similarity to SP:P52005; match to protein family HMM PF03264 YP_001458663.1 identified by similarity to SP:P67825; match to protein family HMM PF03932 YP_001458664.1 yecM; identified by similarity to GB:AAL20824.1; match to protein family HMM PF06185 YP_001458665.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001458666.1 yecT; identified by match to protein family HMM PF07007 YP_001458667.1 identified by similarity to SP:P76297; match to protein family HMM PF06366 YP_001458668.1 membrane protein involved in the flagellar export apparatus YP_001458669.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_001458670.1 identified by glimmer YP_001458671.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation YP_001458672.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble YP_001458673.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_001458674.1 methylates the MCP YP_001458675.1 mediates taxis toward dipeptides YP_001458676.1 identified by similarity to SP:P07017; match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203 YP_001458677.1 identified by similarity to SP:P0A964; match to protein family HMM PF01584 YP_001458678.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component YP_001458679.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001458680.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001458681.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems YP_001458682.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems YP_001458683.1 identified by glimmer YP_001458684.1 identified by match to protein family HMM PF01527 YP_001458685.1 identified by similarity to GB:AAP17067.1; match to protein family HMM PF00665 YP_001458686.1 ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_001458687.1 identified by match to protein family HMM PF00982; match to protein family HMM TIGR02400 YP_001458688.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature YP_001458689.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001458690.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001458691.1 identified by match to protein family HMM PF00532 YP_001458692.1 identified by match to protein family HMM PF00210 YP_001458694.1 identified by glimmer YP_001458695.1 yecR YP_001458696.1 identified by glimmer YP_001458697.1 cytoplasmic iron storage protein YP_001458698.1 yecH; identified by similarity to SP:P46887 YP_001458699.1 identified by match to protein family HMM PF01490; match to protein family HMM PF03222; match to protein family HMM TIGR00837 YP_001458700.1 yecA; identified by match to protein family HMM PF02810; match to protein family HMM TIGR02292 YP_001458701.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560 YP_001458702.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001458703.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_001458705.1 yecF; identified by similarity to SP:P0AD09 YP_001458706.1 regulates genes involved in cell division YP_001458707.1 identified by match to protein family HMM PF00005 YP_001458708.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001458709.1 catalyzes the formation of pyruvate from D-cysteine YP_001458710.1 identified by match to protein family HMM PF00497 YP_001458711.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001458712.1 identified by similarity to SP:Q08860; match to protein family HMM PF00669; match to protein family HMM PF00700 YP_001458713.1 involved in flagellin assembly YP_001458714.1 flagellin specific chaperone YP_001458715.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family YP_001458716.1 converts 1,4-alpha-D-glucans to maltodextrin YP_001458717.1 yedD YP_001458718.1 identified by match to protein family HMM PF04143 YP_001458719.1 yedF; identified by match to protein family HMM PF01206 YP_001458720.1 identified by match to protein family HMM PF02586 YP_001458722.1 identified by match to protein family HMM PF01797 YP_001458724.1 DLP12 prophage; similar to PEBP/RK1P protein family in eukaryotes that inhibits MEK phosphorylation by Raf-1; crystal structure suggests similar properties but exact function is unknown YP_001458725.1 member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation YP_001458726.1 forms a junction between the M-ring and FlgB during flagella biosynthesis YP_001458727.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001458728.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001458729.1 binds to and inhibits the function of flagella specific ATPase FliI YP_001458730.1 involved in type III protein export during flagellum assembly YP_001458731.1 rod/hook and filament chaperone YP_001458732.1 identified by similarity to SP:P52614; match to protein family HMM PF02120 YP_001458733.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_001458734.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_001458735.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001458736.1 with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus YP_001458737.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001458738.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_001458739.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_001458740.1 identified by match to protein family HMM PF00196 YP_001458741.1 identified by similarity to OMNI:NTL01SF1877 YP_001458743.1 identified by glimmer YP_001458744.1 identified by similarity to SP:P64517 YP_001458745.1 identified by match to protein family HMM PF05661 YP_001458746.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950 YP_001458747.1 identified by similarity to SP:P09184; match to protein family HMM PF03852; match to protein family HMM TIGR00632 YP_001458748.1 identified by similarity to SP:P0AED9; match to protein family HMM PF00145; match to protein family HMM TIGR00675 YP_001458749.1 identified by match to protein family HMM PF01966 YP_001458750.1 identified by match to protein family HMM PF01527 YP_001458751.1 identified by similarity to GB:AAP17067.1; match to protein family HMM PF00665 YP_001458753.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress YP_001458754.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR01386 YP_001458755.1 induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced YP_001458756.1 identified by match to protein family HMM PF00576; match to protein family HMM TIGR02962 YP_001458757.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001458758.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_001458759.1 identified by similarity to SP:P76344; match to protein family HMM PF09223 YP_001458760.1 identified by match to protein family HMM PF01292 YP_001458761.1 identified by glimmer YP_001458762.1 identified by glimmer YP_001458763.1 membrane protein; identified by glimmer YP_001458764.1 identified by glimmer YP_001458765.1 identified by glimmer YP_001458766.1 identified by match to protein family HMM PF01757 YP_001458767.1 bacteriophage tail fiber protein-like YP_001458769.1 identified by match to protein family HMM PF04865 YP_001458770.1 identified by match to protein family HMM PF07409 YP_001458771.1 identified by match to protein family HMM PF06890; match to protein family HMM TIGR01644 YP_001458772.1 identified by match to protein family HMM PF06893 YP_001458773.1 bacteriophage protein YP_001458774.1 phage protien-like; identified by glimmer YP_001458775.1 identified by glimmer YP_001458776.1 identified by match to protein family HMM PF01343 YP_001458777.1 identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539 YP_001458778.1 identified by glimmer YP_001458779.1 identified by match to protein family HMM PF05876 YP_001458781.1 identified by glimmer YP_001458782.1 identified by match to protein family HMM PF00589 YP_001458783.1 yeeI; identified by similarity to SP:P76346; match to protein family HMM PF06167 YP_001458785.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_001458786.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_001458787.1 yeeN; identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033 YP_001458788.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_001458789.1 LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB YP_001458790.1 Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation YP_001458791.1 erfK; identified by match to protein family HMM PF03734 YP_001458792.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_001458793.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole YP_001458794.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP YP_001458795.1 identified by similarity to GB:AAZ88711.1 YP_001458796.1 identified by similarity to GB:AAN80940.1 YP_001458797.1 identified by match to protein family HMM PF02126 YP_001458799.1 identified by match to protein family HMM PF01527 YP_001458800.1 identified by match to protein family HMM PF05717 YP_001458801.1 identified by match to protein family HMM PF03050 YP_001458802.1 identified by similarity to GB:AAL08463.1 YP_001458803.1 identified by similarity to GB:AAK00467.1 YP_001458804.1 identified by similarity to GB:AAL08464.2 YP_001458805.1 identified by glimmer YP_001458806.1 identified by match to protein family HMM PF05321 YP_001458807.1 identified by match to protein family HMM PF05930 YP_001458808.1 identified by similarity to GB:AAL08467.1 YP_001458810.1 identified by match to protein family HMM PF01926 YP_001458811.1 identified by similarity to SP:P39180 YP_001458812.1 identified by similarity to GB:ABB61174.1; match to protein family HMM PF06755 YP_001458813.1 identified by similarity to GB:AAP18298.1 YP_001458814.1 identified by similarity to GB:AAK00484.1 YP_001458815.1 identified by glimmer YP_001458816.1 NULL; identified by similarity to SP:Q9XDM6 YP_001458817.1 identified by similarity to SP:P0A8M9; match to protein family HMM PF04363 YP_001458819.1 identified by similarity to GB:1JYH_A; match to protein family HMM PF06445 YP_001458820.1 removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_001458821.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_001458822.1 yeeD; identified by similarity to GB:AAZ88738.1; match to protein family HMM PF01206 YP_001458823.1 identified by match to protein family HMM PF04143 YP_001458824.1 identified by match to protein family HMM PF00324 YP_001458825.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001458826.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370 YP_001458827.1 yoeB; identified by similarity to SP:P69349; match to protein family HMM PF06769; match to protein family HMM TIGR02116 YP_001458828.1 Antitoxin that counteracts the effect of the YoeB toxin YP_001458830.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_001458831.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001458832.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001458833.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_001458834.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001458835.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001458836.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001458837.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_001458838.1 identified by match to protein family HMM PF00534 YP_001458839.1 identified by similarity to GB:BAA07751.1; match to protein family HMM PF00534 YP_001458840.1 identified by similarity to GB:BAA07750.1; match to protein family HMM PF00534 YP_001458841.1 kinase-like; identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_001458842.1 identified by match to protein family HMM PF00005 YP_001458843.1 identified by match to protein family HMM PF01061 YP_001458844.1 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880 YP_001458845.1 identified by similarity to SP:P24174; match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479 YP_001458846.1 identified by glimmer YP_001458847.1 identified by glimmer YP_001458848.1 identified by match to protein family HMM PF03400 YP_001458849.1 identified by match to protein family HMM PF03811 YP_001458850.1 identified by similarity to SP:P76373; match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026 YP_001458851.1 identified by match to protein family HMM PF00908; match to protein family HMM TIGR01221 YP_001458852.1 identified by match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM TIGR01214 YP_001458853.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207 YP_001458854.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181 YP_001458855.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_001458856.1 identified by match to protein family HMM PF01943 YP_001458859.1 identified by match to protein family HMM PF00535 YP_001458860.1 identified by glimmer YP_001458861.1 identified by match to protein family HMM PF00535 YP_001458862.1 identified by match to protein family HMM PF02397; match to protein family HMM TIGR03022; match to protein family HMM TIGR03025 YP_001458863.1 identified by similarity to SP:P38134; match to protein family HMM PF02706 YP_001458864.1 identified by similarity to SP:P0AAB2; match to protein family HMM PF01451 YP_001458865.1 identified by similarity to SP:Q48450; match to protein family HMM PF02563 YP_001458866.1 identified by similarity to GB:AAV27321.1 YP_001458867.1 identified by glimmer YP_001458868.1 identified by glimmer YP_001458869.1 identified by match to protein family HMM PF03811 YP_001458870.1 identified by match to protein family HMM PF03400 YP_001458871.1 identified by glimmer YP_001458872.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_001458873.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs YP_001458874.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_001458875.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_001458876.1 inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine YP_001458879.1 identified by glimmer YP_001458880.1 yegJ; identified by glimmer YP_001458881.1 yegK; identified by similarity to SP:P76395 YP_001458882.1 identified by match to protein family HMM PF00092 YP_001458883.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_001458884.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_001458885.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate YP_001458886.1 identified by match to protein family HMM PF07690 YP_001458887.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_001458888.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport YP_001458890.1 identified by similarity to GB:ABB65576.1 YP_001458891.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role YP_001458892.1 identified by similarity to SP:P36930; match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_001458893.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate YP_001458894.1 identified by match to protein family HMM PF03611; match to protein family HMM TIGR00827 YP_001458895.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001458896.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001458897.1 identified by match to protein family HMM PF08013; match to protein family HMM TIGR02810 YP_001458898.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway YP_001458899.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate YP_001458900.1 identified by match to protein family HMM PF03825; match to protein family HMM PF07690; match to protein family HMM TIGR00889 YP_001458901.1 yegU; identified by match to protein family HMM PF03747 YP_001458902.1 identified by match to protein family HMM PF00294 YP_001458903.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM PF08279 YP_001458904.1 yegX; identified by match to protein family HMM PF01183 YP_001458905.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_001458906.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_001458907.1 yohL; identified by similarity to SP:P64530; match to protein family HMM PF02583 YP_001458908.1 membrane protein conferring nickel and cobalt resistance YP_001458909.1 yohN; identified by similarity to GB:AAN81090.1 YP_001458911.1 identified by match to protein family HMM PF00577 YP_001458912.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001458913.1 identified by match to protein family HMM PF00419 YP_001458914.1 identified by similarity to SP:P0AF08 YP_001458915.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001458916.1 identified by similarity to SP:P33345; match to protein family HMM PF05406 YP_001458917.1 identified by similarity to SP:P33345 YP_001458918.1 identified by glimmer YP_001458919.1 yehL; identified by match to protein family HMM PF07728 YP_001458920.1 yehM; identified by similarity to SP:P33349 YP_001458921.1 yehP; identified by match to protein family HMM PF00092; match to protein family HMM PF05762 YP_001458922.1 yehQ; identified by match to protein family HMM PF04434 YP_001458923.1 yehR; identified by match to protein family HMM PF06998 YP_001458924.1 yehS; identified by match to protein family HMM PF07308 YP_001458925.1 unknown function; when overproduced it confers drug-resistance YP_001458926.1 identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694 YP_001458927.1 identified by similarity to GB:AAZ88835.1 YP_001458928.1 identified by match to protein family HMM PF00528 YP_001458929.1 identified by match to protein family HMM PF00005 YP_001458930.1 identified by match to protein family HMM PF00528 YP_001458931.1 identified by match to protein family HMM PF04069 YP_001458932.1 identified by similarity to SP:P33363; match to protein family HMM PF00933; match to protein family HMM PF01915 YP_001458933.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent YP_001458934.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_001458935.1 yohC; identified by match to protein family HMM PF06930 YP_001458936.1 yohD; identified by similarity to SP:P33366; match to protein family HMM PF09335 YP_001458937.1 identified by match to protein family HMM PF00106 YP_001458938.1 may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_001458939.1 identified by similarity to SP:P33371; match to protein family HMM PF01207 YP_001458940.1 yohJ; identified by match to protein family HMM PF03788 YP_001458941.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_001458942.1 identified by similarity to SP:P0AFY5; match to protein family HMM PF02698 YP_001458943.1 yeiS; identified by similarity to SP:P64539 YP_001458944.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_001458945.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines YP_001458946.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex YP_001458947.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains YP_001458948.1 identified by similarity to SP:P0AEE5; match to protein family HMM PF00532 YP_001458949.1 negative regulator of the mglBAC operon for galactose utilization YP_001458950.1 NULL; identified by match to protein family HMM PF04171; match to protein family HMM PF04235 YP_001458951.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001458952.1 identified by match to protein family HMM PF00756; match to protein family HMM TIGR02821 YP_001458953.1 Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein YP_001458954.1 identified by glimmer YP_001458955.1 identified by match to protein family HMM PF00324 YP_001458956.1 identified by glimmer YP_001458957.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001458958.1 yeiH; identified by match to protein family HMM PF03601; match to protein family HMM TIGR00698 YP_001458959.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_001458960.1 identified by match to protein family HMM PF00294; match to protein family HMM PF08279 YP_001458961.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804 YP_001458962.1 Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively YP_001458963.1 activator of nucleoside metabolism YP_001458964.1 identified by match to protein family HMM PF04227 YP_001458965.1 yeiC; identified by match to protein family HMM PF00294 YP_001458966.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001458967.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers YP_001458968.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr YP_001458969.1 identified by similarity to GB:AAN81159.1 YP_001458970.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00899 YP_001458971.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein YP_001458972.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_001458973.1 yeiR; identified by match to protein family HMM PF02492; match to protein family HMM PF07683 YP_001458974.1 identified by match to protein family HMM PF01569 YP_001458975.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance YP_001458976.1 rtn; identified by similarity to SP:P76446; match to protein family HMM PF00563 YP_001458977.1 identified by match to protein family HMM PF00496 YP_001458978.1 identified by match to protein family HMM PF00528 YP_001458979.1 identified by match to protein family HMM PF00528 YP_001458980.1 identified by match to protein family HMM PF00005 YP_001458981.1 yejG; identified by similarity to SP:P0AD23 YP_001458982.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance YP_001458983.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA YP_001458984.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851 YP_001458985.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001458986.1 identified by similarity to SP:P33920; match to protein family HMM PF04245 YP_001458987.1 identified by glimmer YP_001458988.1 yejL; identified by match to protein family HMM PF07208 YP_001458989.1 identified by match to protein family HMM PF00884 YP_001458990.1 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414 YP_001458991.1 identified by glimmer YP_001458992.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes YP_001458993.1 identified by match to protein family HMM PF03918 YP_001458994.1 identified by similarity to SP:P0AA86; match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR00385 YP_001458995.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR00353 YP_001458996.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_001458997.1 identified by match to protein family HMM PF04995; match to protein family HMM TIGR03141 YP_001458998.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR01191 YP_001458999.1 identified by match to protein family HMM PF03379; match to protein family HMM TIGR01190 YP_001459000.1 ATP-binding protein; required for proper cytochrome c maturation YP_001459001.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone YP_001459002.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA YP_001459003.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA YP_001459004.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway YP_001459005.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_001459006.1 napD; identified by match to protein family HMM PF03927 YP_001459007.1 Predicted role in electron transfer to the periplasmic nitrate reductase NapA. YP_001459008.1 identified by match to protein family HMM PF03974 YP_001459009.1 identified by glimmer YP_001459010.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_001459011.1 efflux pump for the antibacterial peptide microcin J25 YP_001459012.1 identified by similarity to SP:P05050; match to protein family HMM PF03171; match to protein family HMM TIGR00568 YP_001459013.1 identified by similarity to SP:P06134; match to protein family HMM PF00165; match to protein family HMM PF01035; match to protein family HMM PF02805; match to protein family HMM PF02870; match to protein family HMM TIGR00589 YP_001459014.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway YP_001459015.1 allows for ions and hydrophilic solutes to cross the outer membrane YP_001459016.1 identified by glimmer YP_001459017.1 identified by similarity to SP:P39838; match to protein family HMM PF01627; match to protein family HMM PF02518 YP_001459018.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF YP_001459019.1 identified by glimmer YP_001459020.1 identified by similarity to SP:P14376; match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518 YP_001459021.1 with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism YP_001459022.1 with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism YP_001459023.1 identified by similarity to SP:Q01103; match to protein family HMM PF01144; match to protein family HMM TIGR02429 YP_001459024.1 identified by match to protein family HMM PF01144; match to protein family HMM TIGR02428 YP_001459025.1 identified by match to protein family HMM PF02667; match to protein family HMM TIGR00366 YP_001459026.1 identified by similarity to SP:P76461; match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930 YP_001459027.1 yfaP; identified by similarity to GB:ABA76735.1 YP_001459028.1 yfaQ; identified by similarity to GB:AAZ88932.1 YP_001459029.1 identified by match to protein family HMM PF01835; match to protein family HMM PF07703 YP_001459030.2 yfaT; identified by match to protein family HMM PF06672 YP_001459031.1 yfaA; identified by similarity to SP:P17994 YP_001459032.1 negatively supercoils closed circular double-stranded DNA YP_001459033.1 Involved in ubiquinone biosynthesis YP_001459034.1 yfaL; identified by match to protein family HMM PF02415; match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01376; match to protein family HMM TIGR01414; match to protein family HMM TIGR02601 YP_001459035.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001459036.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_001459037.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases YP_001459038.1 identified by similarity to SP:P27294; match to protein family HMM PF06293 YP_001459039.1 yfaH YP_001459040.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic YP_001459041.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell YP_001459042.1 identified by glimmer YP_001459043.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor YP_001459044.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters YP_001459045.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate YP_001459046.1 identified by glimmer YP_001459047.1 yfaD; identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_001459048.1 identified by match to protein family HMM PF03328 YP_001459049.1 identified by match to protein family HMM PF07690 YP_001459050.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_001459051.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339 YP_001459052.1 identified by glimmer YP_001459053.1 identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; match to protein family HMM TIGR00200 YP_001459054.1 identified by glimmer YP_001459055.1 identified by match to protein family HMM PF00293 YP_001459056.1 identified by match to protein family HMM PF00300 YP_001459057.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose YP_001459058.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate YP_001459059.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains YP_001459060.1 identified by match to protein family HMM PF01522 YP_001459061.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A YP_001459062.1 NULL; identified by match to protein family HMM PF00893 YP_001459064.1 NULL; identified by similarity to SP:P37590 YP_001459065.1 identified by match to protein family HMM PF00501; match to protein family HMM TIGR01923 YP_001459066.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_001459067.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_001459068.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA YP_001459069.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_001459070.1 identified by similarity to SP:P38051; match to protein family HMM PF00425; match to protein family HMM TIGR00543 YP_001459071.1 elaB; identified by similarity to GB:CAG75914.1 YP_001459072.1 elaA; identified by match to protein family HMM PF00583 YP_001459073.1 member of metallo-beta-lactamase; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_001459074.1 identified by match to protein family HMM PF03400 YP_001459075.1 identified by match to protein family HMM PF03811 YP_001459076.1 identified by match to protein family HMM PF00092 YP_001459077.1 identified by match to protein family HMM PF04389 YP_001459078.1 yfbM; identified by similarity to SP:P76483; match to protein family HMM PF08974 YP_001459079.1 yfbN; identified by glimmer YP_001459080.1 identified by glimmer YP_001459081.1 identified by glimmer YP_001459082.1 Catalyzes the transfer of electrons from NADH to quinone YP_001459083.1 Catalyzes the transfer of electrons from NADH to quinone YP_001459084.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001459085.1 Catalyzes the transfer of electrons from NADH to quinone YP_001459086.1 Catalyzes the transfer of electrons from NADH to quinone YP_001459087.1 Catalyzes the transfer of electrons from NADH to quinone YP_001459088.1 Catalyzes the transfer of electrons from NADH to quinone YP_001459089.1 Catalyzes the transfer of electrons from NADH to quinone YP_001459090.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_001459091.1 Catalyzes the transfer of electrons from NADH to quinone YP_001459092.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms YP_001459093.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001459094.1 Catalyzes the transfer of electrons from NADH to quinone YP_001459095.1 identified by similarity to SP:P36771; match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001459096.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_001459097.1 identified by similarity to SP:P76491; match to protein family HMM PF01966 YP_001459098.1 identified by match to protein family HMM PF02080; match to protein family HMM PF03600; match to protein family HMM PF06808 YP_001459099.1 identified by similarity to SP:P77625; match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549 YP_001459100.1 identified by match to protein family HMM PF04217 YP_001459101.1 identified by similarity to GB:AAN81291.1 YP_001459102.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_001459103.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_001459104.1 identified by match to protein family HMM PF03606 YP_001459105.1 identified by match to protein family HMM PF00293 YP_001459106.1 identified by similarity to SP:P67095; match to protein family HMM PF00149; match to protein family HMM TIGR00040 YP_001459107.1 identified by similarity to SP:P77544; match to protein family HMM PF02798 YP_001459108.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_001459109.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate YP_001459110.1 identified by match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM PF08338; match to protein family HMM TIGR01777 YP_001459111.1 identified by match to protein family HMM PF00005 YP_001459112.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001459113.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001459114.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_001459115.1 identified by similarity to SP:P09551; match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_001459116.1 identified by similarity to GB:AAX66263.1 YP_001459117.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate YP_001459118.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001459119.1 membrane protein required for colicin V production YP_001459120.1 identified by match to protein family HMM PF05036 YP_001459121.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499 YP_001459122.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_001459123.1 identified by similarity to SP:P0ABP6; match to protein family HMM PF09335 YP_001459124.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001459125.1 identified by similarity to SP:P08390; match to protein family HMM PF01118; match to protein family HMM PF02774 YP_001459126.1 identified by similarity to SP:P05459; match to protein family HMM PF00389; match to protein family HMM PF02826 YP_001459127.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein YP_001459128.1 identified by match to protein family HMM PF07690 YP_001459129.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001459130.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_001459131.1 identified by glimmer YP_001459132.1 yfcL; identified by similarity to GB:ABB66925.1; match to protein family HMM PF08891 YP_001459133.1 identified by match to protein family HMM PF04315 YP_001459134.1 identified by match to protein family HMM PF01925 YP_001459135.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_001459136.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001459137.1 involved in methylation of ribosomal protein L3 YP_001459138.1 identified by match to protein family HMM PF01713 YP_001459140.1 identified by match to protein family HMM PF00419 YP_001459141.1 identified by similarity to GB:AAV78666.1 YP_001459142.1 identified by similarity to GB:AAV76235.1 YP_001459143.1 identified by match to protein family HMM PF00345 YP_001459144.1 identified by match to protein family HMM PF00577 YP_001459145.1 identified by similarity to GB:AAC64152.1; match to protein family HMM PF00419 YP_001459146.1 identified by match to protein family HMM PF00300; match to protein family HMM TIGR00249 YP_001459147.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate YP_001459148.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_001459149.1 yfcZ; identified by match to protein family HMM PF04175; match to protein family HMM TIGR00743 YP_001459150.1 identified by match to protein family HMM PF03349 YP_001459151.1 identified by similarity to GB:AAP17747.1 YP_001459152.1 identified by match to protein family HMM PF04333 YP_001459153.1 identified by similarity to GB:AAN81341.1 YP_001459155.1 regulates the synthesis and expression of the dsdXA operon and dadA gene YP_001459156.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function YP_001459157.1 catalyzes the formation of pyruvate from serine YP_001459158.1 identified by similarity to SP:P52600; match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_001459159.1 identified by similarity to SP:P52599; match to protein family HMM PF00529; match to protein family HMM TIGR00998 YP_001459160.1 response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance YP_001459161.1 identified by similarity to SP:P30855; match to protein family HMM PF00072; match to protein family HMM PF00497; match to protein family HMM PF00512; match to protein family HMM PF01627; match to protein family HMM PF02518 YP_001459162.1 identified by match to protein family HMM PF02515 YP_001459163.1 member of the AEC family of auxin efflux transporters; unknown function YP_001459164.1 catalyzes the formation of formyl-CoA from oxalyl-CoA YP_001459165.1 catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA YP_001459166.1 yfdX; identified by similarity to SP:P76520 YP_001459167.1 yfdY; identified by similarity to GB:AAV76465.1 YP_001459168.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock YP_001459169.1 identified by glimmer YP_001459170.1 identified by match to protein family HMM PF00155 YP_001459171.1 identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694 YP_001459172.1 identified by match to protein family HMM PF00072; match to protein family HMM PF04397 YP_001459173.1 identified by match to protein family HMM PF00165 YP_001459174.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR00848; match to protein family HMM TIGR01417 YP_001459175.1 metalloprotein YP_001459176.1 Xaa-Pro aminopeptidase; limited methionine aminopeptidase YP_001459177.1 identified by match to protein family HMM PF02378; match to protein family HMM TIGR01427 YP_001459178.1 identified by match to protein family HMM PF02379; match to protein family HMM TIGR00829 YP_001459179.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_001459180.1 yfeO YP_001459183.1 identified by match to protein family HMM PF01566; match to protein family HMM TIGR01197 YP_001459184.1 identified by similarity to SP:P33031; match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804 YP_001459185.1 identified by match to protein family HMM PF01609 YP_001459186.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM PF05231 YP_001459187.1 yfeC YP_001459188.1 yfeD; identified by match to protein family HMM PF07037 YP_001459189.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001459190.1 identified by glimmer YP_001459191.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001459192.1 identified by match to protein family HMM PF01758 YP_001459193.1 identified by similarity to SP:P0AD40 YP_001459194.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_001459195.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure YP_001459196.1 role in sulfur assimilation YP_001459197.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_001459198.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_001459199.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system YP_001459200.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_001459201.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_001459202.1 yfeK; identified by similarity to SP:Q47702 YP_001459203.1 identified by match to protein family HMM PF05406 YP_001459205.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide YP_001459206.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR00968 YP_001459207.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import YP_001459208.1 identified by similarity to SP:P16701; match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02139 YP_001459209.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971 YP_001459210.1 identified by similarity to SP:P37440; match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659 YP_001459211.1 yfeT; identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_001459212.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_001459213.1 belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component YP_001459214.1 identified by match to protein family HMM PF00144 YP_001459215.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001459216.1 identified by match to protein family HMM PF04261; match to protein family HMM TIGR01413 YP_001459217.1 identified by match to protein family HMM PF06572 YP_001459219.1 identified by match to protein family HMM PF00583 YP_001459220.1 identified by similarity to SP:P36548; match to protein family HMM PF01520; match to protein family HMM TIGR01409 YP_001459221.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001459222.1 activates the transcription of the ethanolamine utilization operon YP_001459223.1 identified by similarity to SP:Q9ZFU8; match to protein family HMM PF00936 YP_001459224.1 identified by similarity to SP:P0A1C9; match to protein family HMM PF00936 YP_001459225.1 catalyzes the formation of acetaldehyde from ethanolamine YP_001459226.1 identified by similarity to SP:P19264; match to protein family HMM PF06751 YP_001459227.1 ethanolamine utilization protein EutA YP_001459228.1 identified by similarity to SP:P41796; match to protein family HMM PF04346 YP_001459229.1 identified by glimmer YP_001459230.1 identified by similarity to SP:P41795; match to protein family HMM PF00465 YP_001459231.1 identified by similarity to SP:P0A206; match to protein family HMM TIGR02529 YP_001459232.1 identified by similarity to SP:P41793; match to protein family HMM PF00171 YP_001459233.1 identified by similarity to SP:P41792; match to protein family HMM PF03319 YP_001459234.1 identified by match to protein family HMM PF00936 YP_001459235.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta YP_001459236.1 eutT; identified by similarity to SP:Q9ZFV4; match to protein family HMM PF01923 YP_001459237.1 identified by match to protein family HMM PF05899; match to protein family HMM PF06249 YP_001459238.1 eutP; identified by similarity to SP:P0A208; match to protein family HMM TIGR02528 YP_001459239.1 ypfE; identified by similarity to SP:Q9ZFV7; match to protein family HMM PF00936 YP_001459240.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_001459241.1 identified by match to protein family HMM PF00923; match to protein family HMM TIGR00874 YP_001459242.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001459243.1 ypfG; identified by similarity to GB:ABB67033.1; match to protein family HMM PF06674 YP_001459244.1 yffH; identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052 YP_001459245.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) YP_001459246.1 identified by similarity to SP:P27896; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF07730 YP_001459247.1 identified by similarity to SP:P24177; match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_001459248.1 identified by glimmer YP_001459249.1 yffB; identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617 YP_001459250.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001459251.1 identified by similarity to GB:AAN81450.1 YP_001459252.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_001459253.1 ypfI; identified by similarity to GB:ABB67041.1; match to protein family HMM PF05127 YP_001459254.1 identified by match to protein family HMM PF04228 YP_001459255.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001459256.1 identified by similarity to GB:CAA27854.1 YP_001459257.1 identified by match to protein family HMM PF06804 YP_001459258.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001459259.1 negative transcriptional regulator of the gcvTHP operon YP_001459260.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_001459261.1 identified by match to protein family HMM PF00037 YP_001459262.1 identified by similarity to SP:P16430; similarity to SP:P77858; match to protein family HMM PF00146 YP_001459263.1 interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide YP_001459264.1 identified by similarity to SP:P77437; match to protein family HMM PF00361 YP_001459265.1 identified by similarity to SP:P77329; match to protein family HMM PF00329; match to protein family HMM PF00346 YP_001459266.1 probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far YP_001459267.1 identified by similarity to SP:P77668; match to protein family HMM PF01058 YP_001459268.1 identified by match to protein family HMM PF07450 YP_001459269.1 identified by similarity to SP:P19323; match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954 YP_001459270.1 inner membrane protein presumed to act as a formate transporter; member of the hyf operon YP_001459271.1 identified by match to protein family HMM PF01594 YP_001459272.1 identified by match to protein family HMM PF01435 YP_001459273.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR00014 YP_001459274.1 identified by glimmer YP_001459275.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_001459276.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801 YP_001459277.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_001459278.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001459279.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_001459280.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_001459281.1 identified by similarity to SP:P29014; match to protein family HMM PF02541 YP_001459282.1 identified by similarity to GB:AAG57614.1 YP_001459283.1 yfgG; identified by similarity to GB:AAL21400.1 YP_001459284.1 identified by match to protein family HMM PF05433 YP_001459285.1 identified by similarity to SP:P76573 YP_001459286.1 identified by match to protein family HMM PF01381; match to protein family HMM TIGR02607 YP_001459287.1 identified by glimmer YP_001459288.1 identified by match to protein family HMM PF04610; match to protein family HMM TIGR02783 YP_001459289.1 identified by match to protein family HMM TIGR02780 YP_001459291.1 identified by match to protein family HMM PF03811 YP_001459292.1 identified by match to protein family HMM PF03400 YP_001459293.1 identified by match to protein family HMM PF04796 YP_001459294.1 identified by match to protein family HMM PF05930 YP_001459295.1 identified by glimmer YP_001459296.1 identified by match to protein family HMM PF03811 YP_001459297.1 identified by match to protein family HMM PF03400 YP_001459298.1 identified by match to protein family HMM PF00589 YP_001459299.1 identified by glimmer YP_001459300.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001459301.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001459302.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001459303.1 yfgJ; identified by similarity to GB:ABB62753.1; match to protein family HMM PF07191 YP_001459304.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001459305.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_001459306.1 yfgM; identified by similarity to GB:AAP83327.1 YP_001459307.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001459308.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001459309.1 identified by match to protein family HMM PF01381 YP_001459310.1 yfgB; identified by match to protein family HMM PF04055; match to protein family HMM TIGR00048 YP_001459311.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001459312.1 penicillin-insensitive transglycosylase/transpeptidase YP_001459313.1 yfhM; identified by match to protein family HMM PF01835; match to protein family HMM PF07703 YP_001459314.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds YP_001459315.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I YP_001459316.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_001459317.1 identified by similarity to SP:P0C0L9; match to protein family HMM PF04384; match to protein family HMM TIGR03412 YP_001459318.1 identified by match to protein family HMM PF00111; match to protein family HMM TIGR02007 YP_001459319.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_001459320.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_001459321.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein YP_001459322.1 identified by match to protein family HMM PF01592; match to protein family HMM TIGR01999 YP_001459323.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_001459324.1 regulates the expression of the iscRSUA operon YP_001459325.1 identified by glimmer YP_001459326.1 identified by match to protein family HMM PF00588; match to protein family HMM TIGR00050 YP_001459327.1 identified by similarity to SP:P0ADG4; match to protein family HMM PF00459 YP_001459328.1 identified by similarity to SP:P77538 YP_001459329.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters YP_001459330.1 activator of 3-phenylpropionic acid catabolism YP_001459331.1 identified by similarity to SP:Q47139; match to protein family HMM PF00355; match to protein family HMM PF00848 YP_001459332.1 identified by similarity to SP:Q47140; match to protein family HMM PF00866 YP_001459333.1 identified by similarity to SP:P0ABW2; match to protein family HMM PF00355 YP_001459334.1 Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate YP_001459335.1 identified by similarity to SP:P77650; match to protein family HMM PF00070; match to protein family HMM PF07992 YP_001459336.1 yphA; identified by match to protein family HMM PF07681 YP_001459337.1 identified by match to protein family HMM PF01263 YP_001459338.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001459339.1 yphD; identified by match to protein family HMM PF02653 YP_001459340.1 yphE; identified by match to protein family HMM PF00005 YP_001459341.1 yphF; identified by match to protein family HMM PF00532 YP_001459342.1 identified by match to protein family HMM PF03400 YP_001459343.1 identified by similarity to GB:CAA11401.1; match to protein family HMM PF03811 YP_001459344.1 identified by match to protein family HMM PF00515; match to protein family HMM PF07719 YP_001459345.1 identified by match to protein family HMM PF00480 YP_001459346.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001459347.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_001459348.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA YP_001459349.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF07728 YP_001459351.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_001459352.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001459353.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_001459354.1 identified by similarity to SP:P68398; match to protein family HMM PF00383 YP_001459355.1 yfhB; identified by match to protein family HMM TIGR01545 YP_001459356.1 yfhH; identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_001459357.1 yfhL; identified by match to protein family HMM PF00037 YP_001459358.1 NULL; identified by glimmer YP_001459359.1 identified by glimmer YP_001459360.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001459361.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001459362.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_001459363.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001459364.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001459365.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins YP_001459366.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001459367.1 involved in the reduction of the SoxR iron-sulfur cluster YP_001459368.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP YP_001459369.1 identified by match to protein family HMM PF03872; match to protein family HMM PF03873 YP_001459370.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_001459371.1 identified by glimmer YP_001459372.1 catalyzes the formation of oxaloacetate from L-aspartate YP_001459373.1 identified by match to protein family HMM PF05175 YP_001459374.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_001459375.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001459376.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001459377.1 yfiK; identified by match to protein family HMM PF01810 YP_001459378.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit YP_001459379.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_001459380.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068 YP_001459381.1 identified by match to protein family HMM PF03942 YP_001459382.1 identified by similarity to GB:BAA07751.1; match to protein family HMM PF00583; match to protein family HMM PF02629 YP_001459383.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_001459384.1 yfiM YP_001459385.1 identified by similarity to GB:AAN81562.1 YP_001459386.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03346 YP_001459387.1 yfiH; identified by similarity to PDB:1XAF_A; match to protein family HMM PF02578; match to protein family HMM TIGR00726 YP_001459388.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA YP_001459389.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline YP_001459390.1 associated with 30S ribosomal subunit; interferes with translation elongation YP_001459391.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_001459392.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_001459393.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_001459395.1 identified by match to protein family HMM PF03811 YP_001459396.1 identified by match to protein family HMM PF03400 YP_001459397.1 identified by similarity to SP:P64548 YP_001459398.1 identified by match to protein family HMM PF00672; match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_001459399.1 identified by match to protein family HMM PF00691 YP_001459400.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001459401.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001459402.1 Essential for efficient processing of 16S rRNA YP_001459403.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001459404.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_001459405.1 identified by match to protein family HMM PF01578 YP_001459406.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_001459407.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001459408.1 catalyzes the phosphorylation of NAD to NADP YP_001459409.1 identified by similarity to SP:P05824; match to protein family HMM PF02463; match to protein family HMM TIGR00634 YP_001459410.1 identified by match to protein family HMM PF04355 YP_001459411.1 identified by similarity to SP:P52119; match to protein family HMM PF03658 YP_001459412.1 identified by match to protein family HMM PF03364 YP_001459413.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001459414.1 identified by glimmer YP_001459415.1 identified by glimmer YP_001459416.1 identified by match to protein family HMM PF06183 YP_001459417.1 identified by glimmer YP_001459418.1 identified by similarity to SP:P03740; match to protein family HMM PF02413 YP_001459419.1 identified by match to protein family HMM PF03400 YP_001459420.1 identified by match to protein family HMM PF03811 YP_001459421.1 identified by similarity to GB:AAZ89410.1 YP_001459422.1 identified by similarity to GB:AAP17067.1; match to protein family HMM PF00665 YP_001459423.1 identified by match to protein family HMM PF01527 YP_001459424.1 identified by glimmer YP_001459425.1 NULL; identified by glimmer YP_001459426.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02806 YP_001459427.1 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution YP_001459428.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate YP_001459429.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent YP_001459430.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_001459431.1 identified by similarity to SP:P25527; match to protein family HMM PF00324; match to protein family HMM TIGR01773 YP_001459432.1 regulator of gab gene expression YP_001459433.1 identified by match to protein family HMM PF01476; match to protein family HMM PF04972 YP_001459434.1 yqaE; identified by similarity to GB:AAV78517.1; match to protein family HMM PF01679 YP_001459435.1 identified by match to protein family HMM PF01022 YP_001459436.1 ygaP; identified by similarity to SP:P55734 YP_001459437.1 identified by similarity to SP:P0ACG3; match to protein family HMM PF00816 YP_001459438.1 identified by similarity to GB:AAN81672.1 YP_001459439.1 identified by similarity to SP:P64553; match to protein family HMM PF06610 YP_001459440.1 ygaC YP_001459441.1 ygaM; identified by similarity to GB:AAL21687.1; match to protein family HMM PF05957 YP_001459442.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194 YP_001459443.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_001459444.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001459445.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_001459446.1 with ProWX is involved in the high-affinity uptake of glycine betaine YP_001459447.1 with ProVX is involved in the high-affinity uptake of glycine betaine YP_001459448.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine YP_001459449.1 identified by glimmer YP_001459450.1 identified by match to protein family HMM PF07690 YP_001459451.1 ygaZ; identified by match to protein family HMM PF03591 YP_001459452.1 ygaH; identified by similarity to GB:AAZ89437.1 YP_001459453.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB YP_001459454.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR00998 YP_001459455.1 identified by similarity to SP:P27304; match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_001459456.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_001459457.1 involved in the first step of glutathione biosynthesis YP_001459458.1 yqaA YP_001459459.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent YP_001459460.1 affects carbohydrate metabolism; has regulatory role in many processes YP_001459461.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001459462.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_001459463.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001459464.1 ygaD; identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199 YP_001459465.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan YP_001459466.1 identified by match to protein family HMM PF03608; match to protein family HMM TIGR00821 YP_001459467.1 identified by match to protein family HMM PF03612; match to protein family HMM PF07663; match to protein family HMM TIGR00825 YP_001459468.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001459469.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate YP_001459470.1 regulator for glucitol utilization YP_001459471.1 regulates genes involved in glucitol utilization YP_001459472.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate YP_001459473.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_001459474.1 detoxifies nitric oxide using NADH YP_001459475.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase YP_001459476.1 identified by match to protein family HMM PF00708; match to protein family HMM PF01300; match to protein family HMM PF07503; match to protein family HMM TIGR00143 YP_001459477.1 involved in electron transport from formate to hydrogen YP_001459478.1 identified by similarity to SP:P24242; match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001459479.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001459480.1 identified by similarity to SP:P24240; match to protein family HMM PF00232 YP_001459481.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE YP_001459482.1 identified by match to protein family HMM PF07450 YP_001459483.1 identified by similarity to SP:P16433; match to protein family HMM PF01058 YP_001459484.1 electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate YP_001459485.1 identified by similarity to SP:P16431; match to protein family HMM PF00329; match to protein family HMM PF00346 YP_001459486.1 identified by similarity to SP:P16430; match to protein family HMM PF00146 YP_001459487.1 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3) YP_001459488.1 identified by similarity to SP:P0AAK1; match to protein family HMM PF00037 YP_001459489.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon YP_001459490.1 NULL; identified by glimmer YP_001459491.1 plays a role in hydrogenase nickel cofactor insertion YP_001459492.1 GTP hydrolase involved in nickel liganding into hydrogenases YP_001459493.1 HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase YP_001459494.1 identified by similarity to SP:P24192; match to protein family HMM PF01924; match to protein family HMM TIGR00075 YP_001459495.1 identified by similarity to SP:P24193; match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR02124 YP_001459496.1 identified by similarity to SP:P19323; match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; match to protein family HMM PF07728 YP_001459497.1 ygbA; identified by similarity to SP:P25728 YP_001459498.1 NULL; identified by glimmer YP_001459499.1 This protein performs the mismatch recognition step during the DNA repair process YP_001459500.1 identified by match to protein family HMM PF00149 YP_001459501.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_001459502.1 identified by match to protein family HMM PF03446 YP_001459503.1 ygbK; identified by match to protein family HMM PF07005 YP_001459504.1 identified by match to protein family HMM PF00596 YP_001459505.1 ygbM; identified by match to protein family HMM PF01261 YP_001459506.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function YP_001459507.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses YP_001459508.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus YP_001459509.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_001459510.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001459511.1 catalyzes the modification of U13 in tRNA(Glu) YP_001459512.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_001459513.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_001459514.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein YP_001459515.1 identified by similarity to SP:P46141; similarity to GB:AAG42462.1 YP_001459516.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_001459517.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_001459518.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001459519.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3 YP_001459520.1 identified by glimmer YP_001459521.1 identified by glimmer YP_001459522.1 identified by match to protein family HMM TIGR00287 YP_001459523.1 identified by match to protein family HMM PF08798; match to protein family HMM TIGR01907 YP_001459524.1 identified by match to protein family HMM TIGR01868; match to protein family HMM TIGR02593 YP_001459525.1 identified by match to protein family HMM TIGR01869 YP_001459526.1 identified by match to protein family HMM TIGR02548 YP_001459527.1 unknown function; in E. coli this protein is regulated by BaeR, a protein involved in resistance to novobiocin and deoxycholate YP_001459528.1 identified by glimmer YP_001459529.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM TIGR01587 YP_001459530.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_001459531.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_001459532.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity YP_001459533.1 identified by match to protein family HMM PF01242; match to protein family HMM TIGR00039; match to protein family HMM TIGR03367 YP_001459534.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM PF03486; match to protein family HMM PF07992 YP_001459535.1 ygcO; identified by similarity to SP:P68646 YP_001459536.1 identified by match to protein family HMM PF04309 YP_001459537.1 ygcQ; identified by match to protein family HMM PF00766 YP_001459538.1 identified by match to protein family HMM PF01012 YP_001459539.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_001459540.1 ygcU; identified by match to protein family HMM PF01565; match to protein family HMM PF02913 YP_001459541.1 ygcW; identified by match to protein family HMM PF00106 YP_001459542.1 identified by match to protein family HMM PF07690 YP_001459543.1 ygcE; identified by match to protein family HMM PF00370; match to protein family HMM PF02782 YP_001459545.1 identified by glimmer YP_001459546.1 ygcF YP_001459547.1 identified by glimmer YP_001459548.1 identified by match to protein family HMM PF04536 YP_001459549.1 identified by match to protein family HMM PF03811 YP_001459550.1 identified by match to protein family HMM PF03400 YP_001459551.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001459552.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001459553.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era YP_001459554.1 MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system YP_001459555.1 part of the MazF-MazE toxin-antitoxin system; conteracts MazF YP_001459556.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP YP_001459557.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_001459558.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_001459559.1 identified by match to protein family HMM PF01188; match to protein family HMM TIGR03247 YP_001459560.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_001459561.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893 YP_001459562.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001459563.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp YP_001459564.1 identified by similarity to SP:Q46919; match to protein family HMM PF04287 YP_001459565.1 SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_001459566.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_001459567.1 identified by similarity to SP:P0ADS1; match to protein family HMM PF03641 YP_001459568.1 identified by match to protein family HMM TIGR00814 YP_001459569.1 identified by similarity to SP:P16095; match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720 YP_001459570.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups YP_001459571.1 identified by match to protein family HMM PF00465; match to protein family HMM TIGR02638 YP_001459572.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate YP_001459573.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00885 YP_001459574.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose YP_001459575.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR02628 YP_001459576.1 identified by similarity to SP:P0AEN8; match to protein family HMM PF05025 YP_001459577.1 regulates expression of genes involved in L-fucose utilization YP_001459578.1 ygdE; identified by similarity to GB:AAP18132.1 YP_001459579.1 ygdD; identified by match to protein family HMM PF04241 YP_001459580.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_001459581.1 ygdI; identified by match to protein family HMM PF06004 YP_001459582.1 identified by match to protein family HMM PF00266; match to protein family HMM TIGR03392 YP_001459583.1 identified by similarity to SP:P0AGF2; match to protein family HMM PF02657; match to protein family HMM TIGR03391 YP_001459584.1 identified by match to protein family HMM PF00899 YP_001459585.1 identified by glimmer YP_001459586.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_001459587.1 identified by similarity to SP:P63883; match to protein family HMM PF01520; match to protein family HMM TIGR01409 YP_001459588.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_001459589.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_001459590.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_001459591.1 identified by similarity to SP:P05458; match to protein family HMM PF00675; match to protein family HMM PF05193 YP_001459592.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination YP_001459593.1 identified by similarity to SP:P08372; match to protein family HMM TIGR02532 YP_001459594.1 ygdB; identified by similarity to SP:P08370 YP_001459595.1 identified by similarity to SP:P08371; match to protein family HMM PF07963; match to protein family HMM TIGR02532 YP_001459596.1 identified by similarity to SP:P33554; match to protein family HMM PF07963; match to protein family HMM TIGR02532 YP_001459597.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_001459598.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001459599.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr YP_001459600.1 hydrolyzes diadenosine polyphosphate YP_001459601.1 NULL; identified by glimmer YP_001459602.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_001459603.1 identified by match to protein family HMM PF03741 YP_001459604.1 identified by similarity to GB:AAV78717.1; match to protein family HMM PF06004 YP_001459605.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH YP_001459606.1 identified by similarity to SP:P39196; match to protein family HMM PF07690 YP_001459607.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 YP_001459608.1 controls transcription of galETKM YP_001459609.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding YP_001459610.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase YP_001459611.1 identified by match to protein family HMM PF01177; match to protein family HMM TIGR00035 YP_001459612.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879 YP_001459613.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate YP_001459614.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate YP_001459615.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_001459616.1 identified by match to protein family HMM PF01490; match to protein family HMM TIGR00814 YP_001459617.1 yqeH; identified by similarity to GB:AAZ89600.1 YP_001459618.1 identified by match to protein family HMM PF00486 YP_001459619.1 yqeJ YP_001459620.1 identified by glimmer YP_001459621.1 NULL; identified by glimmer YP_001459622.1 NULL; identified by glimmer YP_001459623.1 identified by match to protein family HMM PF07720 YP_001459624.1 identified by match to protein family HMM PF00486; match to protein family HMM PF07719 YP_001459625.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196 YP_001459626.1 identified by similarity to GB:AAA83039.1 YP_001459627.1 identified by glimmer YP_001459628.1 identified by match to protein family HMM PF03811 YP_001459629.1 identified by match to protein family HMM PF03400 YP_001459630.1 identified by similarity to SP:P41785 YP_001459631.1 identified by match to protein family HMM TIGR02105 YP_001459632.1 identified by similarity to GB:BAB60835.1; match to protein family HMM TIGR02554 YP_001459633.1 NULL; identified by match to protein family HMM PF00196 YP_001459634.1 identified by similarity to SP:P37423 YP_001459635.1 identified by similarity to SP:P40727 YP_001459636.1 identified by similarity to GB:BAB60840.1; match to protein family HMM PF01311; match to protein family HMM TIGR01401 YP_001459637.1 identified by similarity to GB:BAB60841.1; match to protein family HMM PF01313; match to protein family HMM TIGR01403 YP_001459638.1 part of a type III secretory system probably involved in invasion into eukaryotic cells YP_001459639.1 involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells YP_001459640.1 identified by similarity to GB:BAB37150.1 YP_001459641.1 identified by similarity to GB:AAP17067.1; match to protein family HMM PF00665 YP_001459642.1 identified by match to protein family HMM PF01527 YP_001459644.1 identified by match to protein family HMM PF01476; match to protein family HMM PF01551 YP_001459645.1 molybdenum cofactor-binding protein; participates in purine salvage YP_001459646.1 FAD-binding subunit; with XdhA and XdhC participates in purine salvage YP_001459647.1 iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage YP_001459648.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954 YP_001459649.1 ygeW; identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR03316 YP_001459650.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate YP_001459651.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases YP_001459652.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position YP_001459653.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_001459654.1 identified by match to protein family HMM PF00364; match to protein family HMM PF02625; match to protein family HMM TIGR03309 YP_001459655.1 yqeC; identified by similarity to SP:Q46809; match to protein family HMM TIGR03172 YP_001459656.1 identified by similarity to SP:Q46810; match to protein family HMM TIGR03310 YP_001459657.1 with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase YP_001459658.1 in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS YP_001459659.1 with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain YP_001459660.1 with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration YP_001459661.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173 YP_001459662.1 Catalyzes the deamination of guanine YP_001459663.1 ygfQ; identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_001459664.1 identified by match to protein family HMM PF00037 YP_001459665.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) YP_001459666.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801; match to protein family HMM TIGR03173 YP_001459667.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate YP_001459668.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001459669.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 YP_001459670.1 5'-3' single-stranded-DNA-specific exonuclease YP_001459671.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity YP_001459672.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001459673.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic YP_001459674.1 ygfX; identified by match to protein family HMM PF07254 YP_001459675.1 identified by similarity to GB:AAN81926.1 YP_001459676.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator YP_001459677.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065 YP_001459678.1 yqfB; identified by match to protein family HMM PF06164 YP_001459679.1 identified by similarity to SP:Q46829; match to protein family HMM PF00232 YP_001459680.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659 YP_001459681.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001459682.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001459683.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001459684.1 visC; identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM TIGR01988 YP_001459685.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone YP_001459686.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide YP_001459687.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown YP_001459688.1 ygfE; identified by match to protein family HMM PF05164 YP_001459689.2 ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function YP_001459690.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001459691.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001459692.1 yqfE; identified by similarity to SP:P64562 YP_001459693.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_001459694.1 MDM; functions in conversion of succinate to propionate YP_001459695.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins YP_001459696.1 catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA YP_001459697.1 identified by match to protein family HMM PF02550 YP_001459698.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001459699.1 identified by similarity to SP:P0ADS8; match to protein family HMM PF04402 YP_001459700.1 Involved in the export of arginine YP_001459701.1 participates in the regulation of osmotic pressure changes within the cel YP_001459702.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_001459703.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001459704.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_001459705.1 identified by similarity to SP:P11664 YP_001459706.1 yggD; identified by match to protein family HMM PF05068 YP_001459707.1 identified by match to protein family HMM PF03320; match to protein family HMM TIGR00330 YP_001459708.1 yggP; identified by similarity to SP:P37084; match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001459709.1 identified by match to protein family HMM PF02302; match to protein family HMM PF02378 YP_001459710.1 identified by match to protein family HMM PF03400 YP_001459711.1 identified by match to protein family HMM PF03811 YP_001459712.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001459713.1 yggG; identified by match to protein family HMM PF01435 YP_001459714.1 catalyzes the formation of putrescine from agmatine YP_001459715.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_001459716.1 yqgB; identified by similarity to GB:AAP18236.1 YP_001459717.1 identified by glimmer YP_001459718.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001459719.1 identified by glimmer YP_001459720.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879 YP_001459721.1 sprT; identified by match to protein family HMM PF03926 YP_001459722.1 identified by similarity to SP:P25736; match to protein family HMM PF04231 YP_001459723.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001459724.1 The second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001459725.1 yqgE; identified by similarity to SP:P0A8W7; match to protein family HMM PF02622 YP_001459726.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001459727.1 identified by glimmer YP_001459728.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001459729.1 identified by match to protein family HMM PF00437; match to protein family HMM TIGR01420 YP_001459730.1 yggS; identified by match to protein family HMM PF01168; match to protein family HMM TIGR00044 YP_001459731.1 identified by match to protein family HMM PF02325 YP_001459732.1 yggU; identified by similarity to GB:AAP18250.1; match to protein family HMM PF02594; match to protein family HMM TIGR00251 YP_001459733.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001459734.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001459735.1 identified by match to protein family HMM PF06717 YP_001459736.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis YP_001459737.1 yggN; identified by similarity to SP:P0ADS9 YP_001459738.1 identified by similarity to GB:AAN81993.1 YP_001459739.1 yggL; identified by match to protein family HMM PF04320 YP_001459740.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001459741.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01084 YP_001459742.1 identified by similarity to GB:AAN81997.1 YP_001459743.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_001459744.1 identified by similarity to SP:P09452; match to protein family HMM PF03825; match to protein family HMM PF07690; match to protein family HMM TIGR00889 YP_001459745.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_001459746.1 identified by match to protein family HMM PF04474 YP_001459747.1 identified by similarity to SP:P41851; match to protein family HMM PF04612 YP_001459748.1 similar to general secretory pathway protein L YP_001459749.1 identified by match to protein family HMM PF03934 YP_001459750.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR01711; match to protein family HMM TIGR02532 YP_001459751.1 identified by match to protein family HMM PF02501; match to protein family HMM PF07963; match to protein family HMM TIGR01707; match to protein family HMM TIGR02532 YP_001459752.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR01708; match to protein family HMM TIGR02532 YP_001459753.1 identified by match to protein family HMM PF07963; match to protein family HMM PF08334; match to protein family HMM TIGR01710; match to protein family HMM TIGR02532 YP_001459754.1 identified by match to protein family HMM PF00482; match to protein family HMM TIGR02120 YP_001459755.1 identified by match to protein family HMM PF00437; match to protein family HMM TIGR02533 YP_001459756.1 identified by match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM TIGR02517 YP_001459757.1 part of the general (type II) secretion pathway (GSP), a signal sequence-dependent process responsible for protein export; involved in trans-location of exoproteins from the cytoplasm to the periplasm YP_001459758.1 yghG YP_001459759.1 identified by similarity to SP:P31712; match to protein family HMM PF01478; match to protein family HMM PF06750 YP_001459760.1 identified by similarity to GB:BAC62719.1 YP_001459762.1 identified by match to protein family HMM PF03811 YP_001459763.1 identified by match to protein family HMM PF03400 YP_001459764.1 identified by glimmer YP_001459765.1 identified by match to protein family HMM PF02652; match to protein family HMM TIGR00795 YP_001459766.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA YP_001459767.1 identified by similarity to SP:P45504; match to protein family HMM PF03928 YP_001459768.1 identified by similarity to SP:P52074; match to protein family HMM PF00037; match to protein family HMM PF02754 YP_001459769.1 identified by match to protein family HMM PF01565 YP_001459770.1 identified by similarity to SP:P52075; match to protein family HMM PF01565; match to protein family HMM PF02913; match to protein family HMM TIGR00387 YP_001459771.1 identified by similarity to SP:P0ACL5; match to protein family HMM PF00392; match to protein family HMM PF07729 YP_001459772.1 identified by glimmer YP_001459773.1 activates fatty acids by binding to coenzyme A YP_001459774.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF05368; match to protein family HMM PF07993; match to protein family HMM PF08659 YP_001459775.1 identified by match to protein family HMM PF00550 YP_001459776.1 identified by similarity to GB:BAB56013.1; match to protein family HMM PF00155; match to protein family HMM PF00202 YP_001459777.1 identified by match to protein family HMM PF03739 YP_001459778.1 identified by match to protein family HMM PF03739 YP_001459779.1 identified by match to protein family HMM TIGR01626 YP_001459781.1 yghQ; identified by match to protein family HMM PF01943 YP_001459782.1 identified by similarity to GB:AAV89941.1 YP_001459784.1 identified by similarity to GB:AAV89942.1 YP_001459785.1 identified by match to protein family HMM PF01384 YP_001459786.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction YP_001459787.1 YghU; B2989; one of eight glutathione transferases from E. coli YP_001459788.1 identified by match to protein family HMM PF01455; match to protein family HMM TIGR00074 YP_001459789.1 plays a role in hydrogenase nickel cofactor insertion YP_001459790.1 identified by similarity to SP:P0AAN1 YP_001459791.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC) YP_001459792.1 involved in hydrogen uptake YP_001459793.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits YP_001459794.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2 YP_001459795.1 involved in hydrogen uptake YP_001459796.1 yghW; identified by similarity to SP:P64577 YP_001459797.1 identified by match to protein family HMM PF00248 YP_001459798.1 yqhA; identified by match to protein family HMM PF03350; match to protein family HMM TIGR00645 YP_001459799.1 identified by match to protein family HMM PF00106 YP_001459800.1 identified by glimmer YP_001459801.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_001459802.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_001459803.1 catalyzes the formation of L-homocysteine from cystathionine YP_001459804.1 yghB; identified by similarity to SP:P0AA60; match to protein family HMM PF09335 YP_001459805.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06719 YP_001459806.1 identified by similarity to SP:Q46856; match to protein family HMM PF00465 YP_001459807.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate YP_001459808.1 identified by glimmer YP_001459809.1 yqhH YP_001459810.1 identified by match to protein family HMM PF04055; match to protein family HMM PF08497 YP_001459811.1 identified by similarity to SP:P26648; match to protein family HMM PF07731; match to protein family HMM PF07732; match to protein family HMM TIGR01409 YP_001459812.1 identified by similarity to SP:P26647; match to protein family HMM PF01553; match to protein family HMM TIGR00530 YP_001459813.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001459814.1 YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system YP_001459815.1 ygiT YP_001459816.1 ygiU; identified by glimmer YP_001459817.1 identified by match to protein family HMM PF06445 YP_001459818.1 ygiW; identified by match to protein family HMM PF04076; match to protein family HMM TIGR00156 YP_001459819.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes YP_001459820.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_001459821.1 ygiZ; identified by similarity to SP:Q46867 YP_001459822.1 identified by similarity to SP:P0AEY5; match to protein family HMM PF02525 YP_001459823.1 ygiN; identified by similarity to PDB:1R6Y_A; match to protein family HMM PF03992 YP_001459824.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001459825.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_001459826.1 identified by similarity to SP:P36650; match to protein family HMM PF00149; match to protein family HMM PF08413 YP_001459827.1 identified by similarity to SP:P0ADV0; match to protein family HMM PF06853 YP_001459828.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_001459829.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_001459830.1 ygiB; identified by similarity to GB:ABG71111.1 YP_001459831.1 identified by match to protein family HMM PF03738 YP_001459832.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine YP_001459833.1 ygiE; identified by match to protein family HMM PF02535 YP_001459834.1 identified by similarity to GB:AAG58180.1 YP_001459835.1 DHBP synthase; functions during riboflavin biosynthesis YP_001459836.1 yqiC; identified by match to protein family HMM PF04380 YP_001459837.1 identified by match to protein family HMM PF00419 YP_001459838.1 identified by match to protein family HMM PF00577 YP_001459839.1 identified by match to protein family HMM PF00345 YP_001459840.1 yqiI; identified by similarity to SP:P76656 YP_001459841.1 Involved in glycogen synthesis. May be involved in glycogen priming YP_001459842.1 identified by similarity to SP:P76657; match to protein family HMM PF07290 YP_001459843.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_001459844.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_001459845.1 ygiF; identified by match to protein family HMM PF01928; match to protein family HMM PF05235 YP_001459846.1 ygiM; identified by similarity to GB:ABB63246.1 YP_001459847.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases YP_001459848.1 identified by glimmer YP_001459849.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001459850.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin YP_001459851.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_001459853.1 identified by match to protein family HMM PF03811 YP_001459854.1 identified by match to protein family HMM PF03400 YP_001459855.1 Involved in the tartrate degradation pathway YP_001459856.1 Involved in the tartrate degradation pathway YP_001459857.1 ygjE; identified by match to protein family HMM PF00939; match to protein family HMM TIGR00785 YP_001459858.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001459859.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001459860.1 synthesizes RNA primers at the replication forks YP_001459861.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_001459862.1 identified by similarity to SP:P0A9H1; match to protein family HMM PF03167 YP_001459863.1 identified by match to protein family HMM PF04954; match to protein family HMM PF08021 YP_001459864.1 yqjI; identified by match to protein family HMM PF03551 YP_001459865.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF08447; match to protein family HMM TIGR00229 YP_001459866.1 identified by glimmer YP_001459867.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate YP_001459868.1 identified by match to protein family HMM PF01588 YP_001459869.1 identified by similarity to SP:P06846; match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001459870.1 in Escherichia coli this is the second beta-galactosidase system YP_001459871.1 in Escherichia coli this is the second beta-galactosidase system YP_001459872.1 identified by match to protein family HMM PF00324 YP_001459873.1 ygjJ; identified by similarity to GB:AAZ89711.1 YP_001459874.1 identified by similarity to SP:P42592 YP_001459875.1 identified by similarity to SP:P42593; match to protein family HMM PF00724; match to protein family HMM PF07992 YP_001459876.1 ygjM; identified by match to protein family HMM PF01381 YP_001459877.1 ygjN; identified by similarity to GB:AAN53007.1 YP_001459878.1 identified by match to protein family HMM PF05175; match to protein family HMM PF08242 YP_001459879.1 ygjP; identified by similarity to SP:P42597; match to protein family HMM PF01863 YP_001459880.1 ygjQ; identified by similarity to SP:P33017; match to protein family HMM PF02698 YP_001459881.1 ygjR; identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_001459882.1 identified by similarity to SP:P42601; match to protein family HMM PF03741 YP_001459883.1 identified by glimmer YP_001459884.1 involved in the import of serine and threonine coupled with the import of sodium YP_001459885.1 ygjV; identified by similarity to SP:P42603 YP_001459886.1 identified by similarity to SP:P42604; match to protein family HMM PF04295; match to protein family HMM PF08666 YP_001459887.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism YP_001459888.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893 YP_001459889.1 identified by match to protein family HMM PF07434 YP_001459891.1 identified by match to protein family HMM PF04449 YP_001459892.1 fimbrial protein-like YP_001459893.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization. YP_001459894.1 identified by similarity to SP:P0AA63; match to protein family HMM PF09335 YP_001459895.1 yqjB; identified by similarity to GB:ABB63281.1 YP_001459896.1 identified by glimmer YP_001459897.1 identified by similarity to SP:P42616; match to protein family HMM PF06476 YP_001459898.1 yqjD; identified by similarity to GB:AAV78931.1; match to protein family HMM PF05957 YP_001459899.1 yqjE; identified by similarity to GB:ABE08983.1 YP_001459900.1 yqjK; identified by similarity to GB:AAZ89836.1 YP_001459901.1 yqjF; identified by match to protein family HMM PF07681 YP_001459903.1 identified by glimmer YP_001459904.1 identified by match to protein family HMM PF05656 YP_001459905.1 identified by glimmer YP_001459906.1 identified by similarity to SP:P64592; match to protein family HMM PF05656 YP_001459907.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001459908.1 identified by match to protein family HMM PF02678 YP_001459909.1 yhaL; identified by similarity to SP:P42625 YP_001459910.1 yhaM; identified by match to protein family HMM PF06354 YP_001459911.1 yhaO; identified by match to protein family HMM TIGR00814 YP_001459912.1 identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720 YP_001459913.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004 YP_001459914.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255 YP_001459915.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism YP_001459916.1 involved in the import of threonine and serine in combination with the import of a proton YP_001459917.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic YP_001459918.1 regulates the tdcABCDEFG operon which is involved in amino acid degradation YP_001459919.1 participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon YP_001459920.1 identified by glimmer YP_001459921.1 yhaB; identified by glimmer YP_001459922.1 identified by glimmer YP_001459923.1 NULL; identified by glimmer YP_001459924.1 yhaD; identified by similarity to SP:P23524; match to protein family HMM PF02595; match to protein family HMM TIGR00045 YP_001459925.1 catalyzes the reduction of tartronate semialdehyde to glycerate YP_001459926.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate YP_001459927.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00893 YP_001459928.1 identified by glimmer YP_001459929.1 identified by similarity to SP:P39829; match to protein family HMM PF04295; match to protein family HMM PF08666; match to protein family HMM TIGR03248 YP_001459930.1 SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation YP_001459931.1 yhaV; identified by similarity to GB:AAZ89862.1 YP_001459932.1 transcriptional repressor for the agaZVWA and agaSYBCDI operons YP_001459933.1 identified by match to protein family HMM PF08013; match to protein family HMM TIGR02810 YP_001459934.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport YP_001459935.1 identified by match to protein family HMM PF03609 YP_001459936.1 identified by similarity to GB:AAF81085.1; match to protein family HMM PF03613 YP_001459937.1 identified by similarity to GB:AAF81086.1; match to protein family HMM PF03610 YP_001459938.1 identified by match to protein family HMM PF01979; match to protein family HMM TIGR00221 YP_001459939.1 identified by match to protein family HMM PF01380; match to protein family HMM TIGR02815 YP_001459940.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway YP_001459941.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport YP_001459942.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport YP_001459943.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport YP_001459944.1 identified by similarity to SP:P42912; match to protein family HMM PF01182 YP_001459945.1 identified by similarity to SP:P22595; match to protein family HMM PF00419 YP_001459946.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001459947.1 identified by similarity to SP:P42915; match to protein family HMM PF00577 YP_001459948.1 identified by similarity to SP:P43319 YP_001459949.1 yraL; identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096 YP_001459950.1 identified by match to protein family HMM PF04348 YP_001459951.1 yraN; identified by match to protein family HMM PF02021; match to protein family HMM TIGR00252 YP_001459952.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein YP_001459953.1 identified by match to protein family HMM PF04972 YP_001459954.1 yraQ; identified by match to protein family HMM PF03773 YP_001459955.1 yraR; identified by match to protein family HMM PF01370 YP_001459956.1 yhbO; identified by match to protein family HMM PF01965; match to protein family HMM TIGR01382 YP_001459957.1 yhbP; identified by similarity to GB:AAZ89875.1 YP_001459958.1 identified by match to protein family HMM PF01541 YP_001459959.1 yhbS; identified by match to protein family HMM PF00583 YP_001459960.1 identified by match to protein family HMM PF02036 YP_001459961.1 identified by match to protein family HMM PF01136 YP_001459962.1 yhbV; identified by match to protein family HMM PF01136 YP_001459963.1 identified by match to protein family HMM PF00296 YP_001459964.1 tryptophan transporter of high affinity YP_001459965.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division YP_001459966.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_001459967.1 identified by similarity to SP:P05055; match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726 YP_001459968.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001459969.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001459970.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001459971.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001459972.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001459973.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001459974.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis YP_001459975.1 identified by match to protein family HMM PF00884 YP_001459976.1 identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810 YP_001459977.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001459978.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate YP_001459979.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins YP_001459980.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_001459981.1 RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability YP_001459982.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001459983.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_001459984.1 identified by glimmer YP_001459985.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001459986.1 yhbE; identified by match to protein family HMM PF00892 YP_001459987.1 involved in the peptidyltransferase reaction during translation YP_001459988.1 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061 YP_001459989.1 identified by similarity to SP:P0AD57; match to protein family HMM PF00348 YP_001459990.1 activator of maltose metabolism genes YP_001459991.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001459992.1 identified by similarity to GB:AAN82389.1 YP_001459994.1 identified by similarity to GB:AAN82391.1 YP_001459995.1 yrbD; identified by match to protein family HMM PF02470 YP_001459996.1 yrbE; identified by match to protein family HMM PF02405; match to protein family HMM TIGR00056 YP_001459997.1 ATP-binding subunit of a ABC toluene efflux transporter YP_001459998.1 YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers YP_001459999.1 identified by similarity to SP:P45395; match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393 YP_001460000.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_001460001.1 yrbK; identified by match to protein family HMM PF06835 YP_001460002.1 LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system YP_001460003.1 identified by similarity to SP:P0A9V1; match to protein family HMM PF00005 YP_001460004.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_001460005.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing YP_001460006.1 identified by similarity to SP:P69829; match to protein family HMM PF00359; match to protein family HMM TIGR01419 YP_001460007.1 yhbJ; identified by match to protein family HMM PF03668 YP_001460008.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_001460009.1 yrbL; identified by similarity to SP:P64611 YP_001460010.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_001460011.1 identified by similarity to SP:P0ABU5; match to protein family HMM PF01965 YP_001460012.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA YP_001460013.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR01212 YP_001460014.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_001460015.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_001460016.1 identified by similarity to GB:ABB63386.1; match to protein family HMM PF06250 YP_001460017.1 identified by glimmer YP_001460018.1 yhcH; identified by similarity to SP:P0AF97; match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_001460019.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein YP_001460020.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_001460021.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00891 YP_001460022.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid YP_001460023.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization YP_001460024.1 identified by match to protein family HMM PF04386 YP_001460025.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_001460026.1 forms a direct contact with the tRNA during translation YP_001460027.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001460028.1 identified by match to protein family HMM PF03969 YP_001460029.1 yhcB; identified by match to protein family HMM PF06295 YP_001460030.1 identified by similarity to SP:P39099; match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037 YP_001460031.1 identified by match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02038 YP_001460032.1 oxidizes malate to oxaloacetate YP_001460033.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_001460034.1 yhcN; identified by similarity to SP:P0AB40; match to protein family HMM PF07338 YP_001460035.1 yhcO; identified by similarity to SP:P64616 YP_001460036.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_001460037.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_001460038.2 membrane protein AaeX; the gene is a member of the aaeXAB operon YP_001460039.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001460040.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA YP_001460041.1 yhdP; identified by match to protein family HMM TIGR02099 YP_001460042.1 involved in the processing of the 5'end of 16S rRNA YP_001460043.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001460044.1 part of cell wall structural complex MreBCD; transmembrane component YP_001460045.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001460046.1 functions in MreBCD complex in some organisms YP_001460047.1 identified by similarity to GB:AAN82447.1 YP_001460048.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_001460049.1 identified by similarity to PDB:1O8C_A; match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02823 YP_001460050.1 identified by similarity to GB:ABB63419.1 YP_001460051.1 identified by glimmer YP_001460052.1 NULL; identified by glimmer YP_001460053.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001460054.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001460055.1 yhdT; identified by match to protein family HMM PF06196 YP_001460056.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_001460057.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001460058.1 identified by glimmer YP_001460059.1 identified by similarity to SP:P0ABT5; match to protein family HMM PF01207; match to protein family HMM TIGR00737 YP_001460060.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_001460061.1 identified by match to protein family HMM PF01555 YP_001460062.1 yhdU; identified by similarity to GB:AAN82469.1 YP_001460063.1 identified by similarity to SP:P0ACT2; match to protein family HMM PF00440; match to protein family HMM PF08361 YP_001460064.1 identified by similarity to SP:P24180; match to protein family HMM PF00529; match to protein family HMM TIGR01730 YP_001460065.1 identified by similarity to SP:P24181; match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_001460066.1 yhdV YP_001460067.1 identified by glimmer YP_001460068.1 yhdW YP_001460069.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_001460070.1 yhdZ; identified by match to protein family HMM PF00005 YP_001460071.1 identified by similarity to GB:AAZ89983.1 YP_001460072.1 yrdB; identified by similarity to SP:P45795; match to protein family HMM PF07369 YP_001460073.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001460074.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA YP_001460075.1 identified by match to protein family HMM PF01396 YP_001460076.1 smg; identified by match to protein family HMM PF04361 YP_001460077.1 smf; identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732 YP_001460078.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001460079.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_001460080.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase YP_001460081.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_001460082.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_001460083.1 identified by match to protein family HMM PF03889 YP_001460084.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_001460085.1 yhdN; identified by similarity to SP:P36677 YP_001460086.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001460087.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001460088.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001460089.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001460090.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001460091.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_001460092.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001460093.1 late assembly protein YP_001460094.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001460095.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001460096.1 binds 5S rRNA along with protein L5 and L25 YP_001460097.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001460098.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001460099.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001460100.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001460101.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001460102.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001460103.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001460104.1 one of the stabilizing components for the large ribosomal subunit YP_001460105.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001460106.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001460107.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001460108.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001460109.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001460110.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001460111.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001460112.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001460113.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001460114.1 calcium-binding protein that may be required for the initiation of chromosome replication YP_001460115.1 identified by match to protein family HMM PF01471 YP_001460116.1 identified by match to protein family HMM TIGR01713 YP_001460117.1 identified by match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM TIGR02517 YP_001460118.1 identified by similarity to SP:P45759; match to protein family HMM PF00437; match to protein family HMM TIGR02533 YP_001460119.1 identified by match to protein family HMM PF00482; match to protein family HMM TIGR02120 YP_001460120.1 identified by match to protein family HMM PF07963; match to protein family HMM PF08334; match to protein family HMM TIGR01710; match to protein family HMM TIGR02532 YP_001460121.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR01708; match to protein family HMM TIGR02532 YP_001460122.1 identified by match to protein family HMM PF02501; match to protein family HMM TIGR01707; match to protein family HMM TIGR02532 YP_001460123.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR01711; match to protein family HMM TIGR02532 YP_001460124.1 identified by match to protein family HMM PF03934 YP_001460125.1 identified by match to protein family HMM PF05134; match to protein family HMM TIGR01709 YP_001460126.1 identified by match to protein family HMM PF04612 YP_001460127.1 identified by match to protein family HMM PF01478 YP_001460128.1 iron storage protein YP_001460129.1 identified by similarity to SP:P0AE56; match to protein family HMM PF04324 YP_001460130.1 identified by glimmer YP_001460131.1 identified by match to protein family HMM PF02839 YP_001460132.1 identified by glimmer YP_001460133.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001460134.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001460135.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001460136.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001460137.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001460138.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001460139.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001460140.1 yheO; identified by similarity to GB:AAV79134.1; match to protein family HMM PF08348 YP_001460141.1 rotamase YP_001460142.1 identified by match to protein family HMM PF04102 YP_001460143.1 rotamase YP_001460144.1 identified by similarity to SP:P0ADW8; match to protein family HMM TIGR02443 YP_001460145.1 involved in potassium efflux YP_001460146.1 required for KefB activity YP_001460147.1 identified by match to protein family HMM PF00005 YP_001460148.1 yheT; identified by match to protein family HMM PF00561 YP_001460149.1 yheU; identified by match to protein family HMM PF06794 YP_001460150.1 identified by match to protein family HMM PF00485 YP_001460151.1 yhfA; identified by match to protein family HMM PF02566 YP_001460152.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_001460153.1 yhfK; identified by match to protein family HMM PF05976; match to protein family HMM TIGR01667 YP_001460154.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_001460155.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity YP_001460156.1 identified by similarity to SP:P20605; match to protein family HMM PF02661 YP_001460157.1 identified by similarity to SP:P20752; match to protein family HMM PF00160 YP_001460158.1 identified by match to protein family HMM PF07690 YP_001460159.1 identified by similarity to SP:P08201; match to protein family HMM PF00070; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM PF04324; match to protein family HMM PF07992; match to protein family HMM TIGR02374 YP_001460160.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations YP_001460161.1 member of the FNT family of formate and nitrite transporters YP_001460162.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin YP_001460163.1 yhfL YP_001460164.1 inner membrane protein possibly involved in fructoselysine transport; member of the flr operon YP_001460165.1 catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine YP_001460166.1 YhfOP; YhfP; YhfO; FrlC; catalyzes the interconversion of fructoselysine and psicoselysine YP_001460167.1 identified by match to protein family HMM PF00294 YP_001460168.1 may act as a transcriptional regulator of a fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes YP_001460169.1 yhfS; identified by similarity to GB:ABB67851.1 YP_001460170.1 identified by similarity to SP:P45546 YP_001460171.1 yhfU YP_001460172.1 phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE) YP_001460173.1 identified by match to protein family HMM PF01676; match to protein family HMM PF08342 YP_001460174.1 yhfX; identified by match to protein family HMM PF01168 YP_001460175.1 yhfY YP_001460176.1 yhfZ; identified by similarity to OMNI:NTL01SF3196 YP_001460177.1 identified by similarity to GB:AAZ87440.1 YP_001460178.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001460179.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_001460180.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_001460181.1 identified by match to protein family HMM PF02086; match to protein family HMM TIGR00571 YP_001460182.1 identified by similarity to SP:P11557; match to protein family HMM PF05036 YP_001460183.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001460184.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001460185.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa YP_001460186.1 yrfB YP_001460187.1 yrfC; identified by match to protein family HMM PF05137 YP_001460188.1 yrfD; identified by similarity to SP:P45753 YP_001460189.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits YP_001460190.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_001460191.1 identified by glimmer YP_001460192.1 identified by similarity to SP:P45800; match to protein family HMM PF07095 YP_001460193.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509 YP_001460194.1 identified by similarity to SP:P45802; match to protein family HMM PF01479 YP_001460195.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_001460196.1 identified by similarity to SP:P45804 YP_001460197.1 identified by similarity to GB:AAN44882.1 YP_001460198.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001460199.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_001460200.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_001460201.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001460202.1 identified by similarity to SP:P46837; match to protein family HMM PF00575 YP_001460203.1 identified by match to protein family HMM PF04023 YP_001460204.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake YP_001460205.1 yhgG; identified by match to protein family HMM PF09012 YP_001460206.1 yhgA; identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_001460207.1 Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis YP_001460208.1 involved in high-affinity gluconate transport YP_001460209.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_001460210.1 identified by glimmer YP_001460211.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_001460212.1 amylomaltase; acts to release glucose from maltodextrins YP_001460213.1 identified by similarity to SP:P00490; match to protein family HMM PF00343; match to protein family HMM TIGR02093 YP_001460214.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides YP_001460215.1 catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester YP_001460216.1 identified by similarity to SP:P46850; match to protein family HMM PF01139 YP_001460217.1 identified by similarity to SP:P38035; match to protein family HMM PF00158; match to protein family HMM PF06956; match to protein family HMM PF07728 YP_001460218.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism YP_001460219.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity YP_001460220.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine YP_001460221.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_001460222.1 NULL YP_001460223.1 identified by similarity to GB:AAL22389.1 YP_001460225.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093 YP_001460226.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_001460227.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_001460228.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen YP_001460229.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_001460230.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001460231.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP) YP_001460232.1 identified by similarity to SP:P0AC96; match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_001460233.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate YP_001460234.1 identified by similarity to SP:P0ACP5; match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001460235.1 identified by match to protein family HMM PF02678; match to protein family HMM PF07883 YP_001460236.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_001460237.1 YhhY; regulated by the fur regulator; unknown function YP_001460238.1 identified by match to protein family HMM PF01844; match to protein family HMM PF05638; match to protein family HMM TIGR03344 YP_001460240.1 identified by glimmer YP_001460241.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides YP_001460242.1 yhhA YP_001460243.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate YP_001460244.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_001460245.1 with UgpABC is involved in uptake of glycerol-3-phosphate YP_001460246.1 with UgpEC is involved in the uptake of glycerol-3-phosphate YP_001460247.1 with UgpACE is involved in the uptake of glycerol-3-phosphate YP_001460248.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001460249.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001460250.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001460251.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter YP_001460252.1 identified by match to protein family HMM PF01094 YP_001460253.1 identified by glimmer YP_001460254.1 identified by match to protein family HMM PF00583 YP_001460255.1 identified by match to protein family HMM PF01094 YP_001460256.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_001460257.1 ABC transporter membrane protein YP_001460258.1 ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions YP_001460259.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins YP_001460260.1 catalyzes the methylation of 16S rRNA at position G966 YP_001460261.1 yhhL; identified by match to protein family HMM PF06611 YP_001460262.1 identified by similarity to GB:CAG77246.1 YP_001460263.1 identified by match to protein family HMM PF07947 YP_001460264.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury YP_001460265.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs YP_001460266.1 yhhQ; identified by match to protein family HMM PF02592; match to protein family HMM TIGR00697 YP_001460268.1 identified by match to protein family HMM PF07690 YP_001460269.1 yhhT; identified by match to protein family HMM PF01594 YP_001460270.1 identified by similarity to SP:P37623; match to protein family HMM PF01648 YP_001460271.1 identified by match to protein family HMM PF00496; match to protein family HMM TIGR02294 YP_001460272.1 with NikACDE is involved in nickel transport into the cell YP_001460273.1 with NikABDE is involved in nickel transport into the cell YP_001460274.1 with NikABCE is involved in nickel transport into the cell YP_001460275.1 with NikABCD is involved with nickel transport into the cell YP_001460276.1 Inhibits transcription at high concentrations of nickel YP_001460277.1 identified by similarity to SP:P16917; match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643 YP_001460278.1 identified by match to protein family HMM PF01061 YP_001460279.1 identified by match to protein family HMM PF00005; match to protein family HMM PF01061 YP_001460280.1 identified by match to protein family HMM PF00529 YP_001460281.1 identified by match to protein family HMM PF03811 YP_001460282.1 identified by match to protein family HMM PF03400 YP_001460283.1 identified by glimmer YP_001460284.1 identified by glimmer YP_001460285.1 yhiN; identified by match to protein family HMM PF01266; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR00275 YP_001460286.1 identified by match to protein family HMM PF01384 YP_001460287.1 identified by glimmer YP_001460288.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_001460289.1 identified by similarity to SP:P0AED0; match to protein family HMM PF00582 YP_001460290.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function YP_001460291.1 predicted SAM-dependent methyltransferase YP_001460292.1 identified by similarity to SP:P27298; match to protein family HMM PF01432 YP_001460293.1 identified by similarity to SP:P37634; match to protein family HMM PF04378 YP_001460294.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_001460295.1 identified by glimmer YP_001460296.1 identified by glimmer YP_001460297.1 regulates the expression of of the arsRBC involved in resistance to arsenic YP_001460298.1 identified by match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM TIGR00935 YP_001460299.1 identified by similarity to SP:P08692; match to protein family HMM PF03960; match to protein family HMM TIGR00014 YP_001460300.1 identified by similarity to GB:AAN82738.1 YP_001460301.1 yhiS YP_001460302.1 identified by match to protein family HMM PF03843; match to protein family HMM TIGR00752 YP_001460303.1 yhiF; identified by similarity to SP:P37195; match to protein family HMM PF00196 YP_001460304.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli YP_001460306.1 inactive form YP_001460307.1 hdeD; identified by similarity to SP:P0AET7 YP_001460308.1 yhiE; identified by similarity to SP:P63204 YP_001460309.1 with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds YP_001460310.1 identified by similarity to SP:P37637; match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_001460311.1 identified by similarity to SP:P63201; match to protein family HMM PF00165 YP_001460312.1 identified by glimmer YP_001460313.1 regulates genes in response to acid and/or during stationary phase YP_001460314.1 identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788 YP_001460315.1 identified by match to protein family HMM PF03150 YP_001460316.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose YP_001460317.1 identified by match to protein family HMM PF00196; match to protein family HMM PF08281 YP_001460318.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001460319.1 identified by match to protein family HMM PF03631; match to protein family HMM TIGR00766 YP_001460320.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_001460321.1 identified by match to protein family HMM PF05170 YP_001460322.1 in Escherichia coli this protein is involved in flagellar function YP_001460323.1 identified by similarity to SP:P45416; match to protein family HMM PF00294 YP_001460324.1 yhjJ; identified by match to protein family HMM PF00675; match to protein family HMM PF05193 YP_001460325.1 involved in the transport of C4-dicarboxylates across the membrane YP_001460326.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase from E. coli YP_001460327.1 identified by similarity to SP:P37650; match to protein family HMM PF05420 YP_001460328.1 identified by similarity to SP:P37659 YP_001460329.1 identified by glimmer YP_001460330.1 identified by glimmer YP_001460331.1 identified by match to protein family HMM TIGR00814 YP_001460332.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_001460333.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF YP_001460334.1 identified by match to protein family HMM PF00528 YP_001460335.1 transports peptides consisting of two or three amino acids YP_001460337.1 identified by match to protein family HMM PF00496 YP_001460338.1 identified by glimmer YP_001460339.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide YP_001460340.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00890 YP_001460341.1 identified by similarity to SP:P37663 YP_001460342.1 constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine YP_001460343.1 identified by match to protein family HMM PF00583 YP_001460344.1 identified by similarity to SP:P20099; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509 YP_001460345.1 identified by similarity to SP:P37665; match to protein family HMM PF00691; match to protein family HMM PF05433 YP_001460346.1 identified by similarity to SP:P37666; match to protein family HMM PF00389; match to protein family HMM PF02826 YP_001460347.1 yiaF YP_001460348.1 yiaG; identified by similarity to SP:P0A9V5 YP_001460349.1 identified by match to protein family HMM PF00313 YP_001460350.1 identified by similarity to SP:P37305; match to protein family HMM PF01848 YP_001460351.1 identified by similarity to GB:AAL72400.1 YP_001460352.1 identified by similarity to GB:AAB18535.2; match to protein family HMM PF00665 YP_001460353.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001460354.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001460356.1 yiaH; identified by match to protein family HMM PF01757 YP_001460357.1 yiaA; identified by match to protein family HMM PF05360 YP_001460358.1 yiaB; identified by match to protein family HMM PF05360 YP_001460359.1 identified by similarity to SP:P29444; match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR01312 YP_001460360.1 catalyzes the interconversion of D-xylose to D-xylulose YP_001460361.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity YP_001460362.1 with XylFH is part of the high affinity xylose ABC transporter YP_001460363.1 identified by match to protein family HMM PF02653 YP_001460364.1 identified by match to protein family HMM PF00165 YP_001460365.1 identified by match to protein family HMM PF01832 YP_001460366.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds YP_001460367.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis YP_001460368.1 identified by similarity to GB:ABB67500.1 YP_001460369.1 yiaI; identified by match to protein family HMM PF00037 YP_001460370.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339 YP_001460371.1 NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate YP_001460372.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_001460373.1 membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO YP_001460374.1 identified by match to protein family HMM PF06808; match to protein family HMM TIGR00786 YP_001460375.1 identified by match to protein family HMM PF03480; match to protein family HMM TIGR00787 YP_001460376.1 identified by similarity to SP:P37677; match to protein family HMM PF00370; match to protein family HMM PF02782 YP_001460377.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate YP_001460378.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate YP_001460379.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_001460380.1 identified by similarity to SP:P0A908; match to protein family HMM PF06629; match to protein family HMM TIGR03304 YP_001460381.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001460382.1 identified by match to protein family HMM PF00529 YP_001460383.1 yiaW; identified by similarity to GB:AAF95962.1 YP_001460384.1 identified by glimmer YP_001460385.1 identified by similarity to SP:P37685; match to protein family HMM PF00171 YP_001460386.1 identified by match to protein family HMM PF00465 YP_001460387.1 identified by similarity to SP:P14081; match to protein family HMM PF00009; match to protein family HMM PF03144; match to protein family HMM PF09106; match to protein family HMM PF09107; match to protein family HMM TIGR00475 YP_001460388.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_001460389.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_001460390.1 identified by glimmer YP_001460391.1 yibA; identified by match to protein family HMM PF03130 YP_001460392.1 identified by match to protein family HMM PF03527 YP_001460393.1 identified by match to protein family HMM PF00529 YP_001460394.1 yibI; identified by similarity to GB:AAN82851.1 YP_001460395.1 identified by glimmer YP_001460396.1 identified by similarity to SP:P00550; match to protein family HMM PF00359; match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851 YP_001460397.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_001460398.1 Acts as a repressor of the mtlAD operon YP_001460399.1 identified by similarity to SP:P0AA60; similarity to RF:NP_462588.1 YP_001460400.1 yibL YP_001460401.1 identified by glimmer YP_001460402.1 NULL; identified by glimmer YP_001460403.1 NULL YP_001460404.1 identified by match to protein family HMM PF03895; match to protein family HMM PF05658; match to protein family HMM PF05662 YP_001460405.1 identified by match to protein family HMM PF02652; match to protein family HMM TIGR00795 YP_001460406.1 represses the lctPRD operon YP_001460407.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration YP_001460408.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates YP_001460409.1 catalyzes the O-acetylation of serine YP_001460410.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001460411.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_001460412.1 identified by similarity to SP:P0AC62; match to protein family HMM PF00462; match to protein family HMM TIGR02181 YP_001460413.1 identified by match to protein family HMM PF00581 YP_001460414.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_001460415.2 identified by match to protein family HMM PF01551 YP_001460416.1 identified by match to protein family HMM PF04748 YP_001460417.1 identified by match to protein family HMM PF00535 YP_001460418.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_001460419.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_001460420.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose YP_001460421.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core YP_001460422.1 identified by match to protein family HMM PF01075; match to protein family HMM TIGR02193 YP_001460423.1 identified by match to protein family HMM PF04932 YP_001460424.1 identified by match to protein family HMM PF00535 YP_001460425.1 identified by similarity to GB:AAC69673.1; match to protein family HMM PF01501; match to protein family HMM PF08437 YP_001460426.1 identified by similarity to SP:P27240; match to protein family HMM PF06176 YP_001460427.1 identified by similarity to SP:P27129; match to protein family HMM PF01501; match to protein family HMM PF08437 YP_001460428.1 identified by match to protein family HMM PF01501; match to protein family HMM PF08437 YP_001460429.1 identified by match to protein family HMM PF06293 YP_001460430.1 identified by similarity to SP:P25740; match to protein family HMM PF00534 YP_001460431.1 identified by similarity to SP:P25742; match to protein family HMM PF01075; match to protein family HMM TIGR02201 YP_001460432.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_001460433.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001460434.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001460435.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001460436.1 required for 70S ribosome assembly YP_001460437.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_001460438.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_001460439.1 catalyzes the formation of dUMP from dUTP YP_001460440.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_001460441.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001460442.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001460443.1 identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255 YP_001460444.1 identified by glimmer YP_001460445.1 identified by match to protein family HMM PF03458 YP_001460446.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ YP_001460447.1 Essential for recycling GMP and indirectly, cGMP YP_001460448.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001460449.1 identified by similarity to SP:P17580; match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691 YP_001460450.1 specifically modifies tRNA at position G18 YP_001460451.1 catalyzes branch migration in Holliday junction intermediates YP_001460452.1 identified by similarity to SP:P0AER8; match to protein family HMM PF03616; match to protein family HMM TIGR00210 YP_001460453.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801 YP_001460454.1 yicH; identified by match to protein family HMM PF05170 YP_001460455.1 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides YP_001460456.1 may be involved in the transport of galactosides-pentoses-hexuronides YP_001460457.1 identified by glimmer YP_001460458.1 identified by similarity to SP:P31436; match to protein family HMM PF07690; match to protein family HMM TIGR00899 YP_001460459.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950 YP_001460460.1 identified by similarity to SP:P04846; match to protein family HMM PF03180; match to protein family HMM TIGR00363 YP_001460461.1 identified by similarity to SP:Q5PC60 YP_001460462.1 experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS YP_001460463.1 yicN; identified by match to protein family HMM PF06711 YP_001460464.1 yicO; identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_001460465.1 catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type YP_001460466.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate YP_001460467.1 membrane protein regulates uhpT expression YP_001460468.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph YP_001460469.1 response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter YP_001460470.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit YP_001460471.1 identified by similarity to SP:P08142; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118 YP_001460472.1 identified by similarity to SP:P03061; match to protein family HMM PF08049 YP_001460473.1 multidrug efflux protein involved in adaptation to low energy shock YP_001460475.1 yidG YP_001460476.1 yidH; identified by match to protein family HMM PF02656 YP_001460477.1 identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766 YP_001460478.1 identified by similarity to SP:P54716; match to protein family HMM PF02056 YP_001460479.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00852; match to protein family HMM TIGR02005 YP_001460480.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_001460481.1 identified by match to protein family HMM PF02080; match to protein family HMM PF06826; match to protein family HMM TIGR01625 YP_001460482.1 identified by glimmer YP_001460483.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent YP_001460484.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress YP_001460485.1 yidQ; identified by match to protein family HMM PF07119 YP_001460486.1 yidR; identified by similarity to GB:AAP18981.1 YP_001460487.1 FAD/NAD(P)-binding domain YP_001460488.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00881; match to protein family HMM TIGR00893 YP_001460489.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_001460490.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism YP_001460491.1 identified by match to protein family HMM PF05035 YP_001460492.1 identified by similarity to SP:P31460; match to protein family HMM PF00392; match to protein family HMM PF07729 YP_001460494.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins YP_001460495.1 yidB; identified by match to protein family HMM PF06078 YP_001460496.1 identified by similarity to GB:AAN78514.1 YP_001460497.1 negatively supercoils closed circular double-stranded DNA YP_001460498.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001460499.1 binds the polymerase to DNA and acts as a sliding clamp YP_001460500.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001460501.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_001460502.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_001460503.1 identified by match to protein family HMM PF01809; match to protein family HMM TIGR00278 YP_001460504.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_001460505.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001460506.1 identified by match to protein family HMM TIGR02616 YP_001460507.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan YP_001460508.1 tryptophan transporter of low affinity YP_001460509.1 Confers resistance to chloramphenicol YP_001460510.1 Involved in anaerobic NO protection YP_001460511.1 yieE; identified by similarity to GB:AAP19005.1 YP_001460512.1 yieF; identified by match to protein family HMM PF03358 YP_001460513.1 identified by match to protein family HMM PF00860 YP_001460514.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily YP_001460515.1 might be involved in hypersensitivity to nitrofurzone YP_001460516.1 identified by similarity to SP:P31469; match to protein family HMM PF03691 YP_001460517.1 identified by match to protein family HMM PF01182 YP_001460518.1 identified by similarity to SP:P26218; match to protein family HMM PF02264 YP_001460519.1 identified by match to protein family HMM PF00232 YP_001460520.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001460521.1 positive regulator of the beta-glucoside operon; transcriptional antiterminator YP_001460522.1 identified by glimmer YP_001460523.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_001460524.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR00972 YP_001460525.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_001460526.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_001460527.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00975 YP_001460528.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001460529.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_001460530.1 identified by glimmer YP_001460531.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001460532.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001460533.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001460534.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001460535.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001460536.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001460537.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001460538.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001460539.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation YP_001460540.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001460541.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001460542.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001460543.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_001460544.1 catalyzes the formation of asparagine from aspartate and ammonia YP_001460545.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA YP_001460546.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase YP_001460547.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH YP_001460548.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_001460549.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain YP_001460550.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B YP_001460551.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system YP_001460552.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_001460553.1 identified by similarity to GB:AAP17067.1; match to protein family HMM PF00665 YP_001460554.1 identified by match to protein family HMM PF01527 YP_001460555.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_001460556.1 yieP; identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_001460557.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon YP_001460558.1 yifE; identified by similarity to GB:AAZ90461.1; match to protein family HMM PF04219 YP_001460559.1 among the AAA+ ATPases, the YifB protease belongs to the Helix 2 insert clade; unknown function YP_001460560.1 identified by match to protein family HMM PF08046 YP_001460561.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_001460562.1 identified by similarity to SP:P0ADG3 YP_001460563.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001460564.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001460565.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_001460566.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_001460567.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001460568.1 identified by match to protein family HMM PF00639 YP_001460569.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication YP_001460570.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation YP_001460571.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_001460572.1 identified by similarity to SP:P0AA25; match to protein family HMM PF00085; match to protein family HMM TIGR01068 YP_001460573.1 identified by glimmer YP_001460574.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001460575.1 identified by glimmer YP_001460576.1 identified by match to protein family HMM PF00953; match to protein family HMM TIGR02380 YP_001460577.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein YP_001460578.1 identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236 YP_001460579.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid YP_001460580.1 identified by similarity to SP:P27830; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181 YP_001460581.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207 YP_001460582.1 wecD; identified by match to protein family HMM PF00583; match to protein family HMM TIGR02382 YP_001460583.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis YP_001460585.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis YP_001460586.1 enterobacterial common antigen polymerase YP_001460587.1 identified by match to protein family HMM PF03808; match to protein family HMM TIGR00696 YP_001460588.1 identified by glimmer YP_001460589.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function YP_001460590.1 identified by similarity to SP:P25550; match to protein family HMM PF04055 YP_001460591.1 identified by similarity to SP:P25549 YP_001460592.1 identified by glimmer YP_001460593.1 identified by match to protein family HMM PF07219; match to protein family HMM PF07719; match to protein family HMM TIGR00540 YP_001460594.1 identified by match to protein family HMM PF04375 YP_001460595.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis YP_001460596.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001460597.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_001460598.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly YP_001460601.1 identified by glimmer YP_001460604.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001460605.1 identified by similarity to SP:P23305; match to protein family HMM PF04340 YP_001460606.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001460607.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function YP_001460608.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_001460609.1 yigE YP_001460610.1 identified by glimmer YP_001460611.1 responsible for the influx of magnesium ions YP_001460612.1 yigF YP_001460613.1 rarD; identified by match to protein family HMM PF00892; match to protein family HMM TIGR00688 YP_001460614.1 yigI; identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_001460615.1 catalyzes the hydrolysis of phosphatidylcholine YP_001460616.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway YP_001460617.1 identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949 YP_001460618.1 identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949 YP_001460619.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates YP_001460620.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium YP_001460621.1 yigM; identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950 YP_001460622.1 identified by similarity to SP:P0A9F9; match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001460623.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_001460624.1 identified by match to protein family HMM PF01738 YP_001460625.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_001460626.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner YP_001460627.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_001460628.1 yigP; identified by match to protein family HMM PF06843 YP_001460629.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions YP_001460630.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001460631.1 mediates the export of protein precursors bearing twin-arginine signal peptides YP_001460632.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane YP_001460633.1 magnesium dependent; not involved in the Sec-independent protein export system YP_001460634.1 identified by similarity to SP:P26614; match to protein family HMM PF02357; match to protein family HMM TIGR01955 YP_001460635.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol YP_001460636.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_001460637.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001460638.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001460639.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_001460640.1 yigZ; identified by match to protein family HMM PF01205; match to protein family HMM PF09186; match to protein family HMM TIGR00257 YP_001460641.1 identified by match to protein family HMM PF02386; match to protein family HMM TIGR00933 YP_001460642.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX YP_001460643.1 identified by match to protein family HMM PF03205; match to protein family HMM TIGR00176 YP_001460644.1 Links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_001460645.1 yihD; identified by match to protein family HMM PF06288 YP_001460646.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_001460647.1 identified by similarity to SP:P52235; match to protein family HMM PF01323 YP_001460648.1 identified by glimmer YP_001460649.1 yihF; identified by match to protein family HMM PF06097 YP_001460650.1 identified by match to protein family HMM PF01553 YP_001460651.1 identified by glimmer YP_001460652.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_001460653.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001460654.1 identified by similarity to SP:Q8X8G9; match to protein family HMM PF04220 YP_001460655.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001460656.1 identified by glimmer YP_001460657.1 identified by glimmer YP_001460658.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54 YP_001460659.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation YP_001460660.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_001460661.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394 YP_001460662.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_001460663.1 identified by match to protein family HMM PF01261 YP_001460664.1 identified by match to protein family HMM PF07690 YP_001460665.1 identified by match to protein family HMM PF00392; match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_001460666.1 identified by match to protein family HMM PF00294 YP_001460667.1 identified by match to protein family HMM PF03446 YP_001460668.1 identified by match to protein family HMM PF01791 YP_001460669.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001460670.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_001460671.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_001460672.1 identified by match to protein family HMM PF01263 YP_001460673.1 identified by similarity to SP:P0A8Y4; match to protein family HMM PF00702; match to protein family HMM TIGR01509 YP_001460674.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_001460675.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_001460676.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR02447 YP_001460677.1 identified by glimmer YP_001460678.1 identified by match to protein family HMM PF01402 YP_001460679.1 yiiF YP_001460680.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001460681.1 required for the formation of active formate dehydrogenase YP_001460682.1 cytochrome b556(FDO) component; heme containing YP_001460683.1 identified by similarity to SP:P0AAJ5; match to protein family HMM PF00037; match to protein family HMM PF09163; match to protein family HMM TIGR01582 YP_001460684.1 Selenoprotein. identified by similarity to SP:P32176; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR01553 YP_001460685.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_001460686.1 yiiG YP_001460687.1 repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system YP_001460688.1 with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars YP_001460689.1 identified by similarity to SP:P32154; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR01427 YP_001460690.1 with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system YP_001460691.1 yiiL; identified by match to protein family HMM PF05336; match to protein family HMM TIGR02625 YP_001460692.1 identified by similarity to SP:P32169; match to protein family HMM PF00596; match to protein family HMM TIGR02624 YP_001460693.1 catalyzes the formation of L-rhamnulose from L-rhamnose YP_001460694.1 catalyzes the ATP-dependent phosphorylation of rhamnulose YP_001460695.1 identified by glimmer YP_001460696.1 activates the expression of the rhaBAD operon and rhaT gene YP_001460697.1 activates the expression of rhaRS in response to L-rhamnose YP_001460698.1 transports L-rhamnose and L-lyxose into the cell YP_001460699.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals YP_001460701.1 transports degraded pectin products into the bacterial cell YP_001460702.1 yiiM; identified by match to protein family HMM PF03473; match to protein family HMM PF03475 YP_001460703.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors YP_001460704.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system YP_001460705.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates YP_001460706.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers YP_001460707.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_001460708.1 identified by similarity to GB:ABB67500.1 YP_001460709.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971 YP_001460710.1 identified by similarity to SP:P06282; match to protein family HMM PF02611; match to protein family HMM TIGR00672 YP_001460711.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001460712.1 yiiQ; identified by match to protein family HMM PF07305 YP_001460713.1 yiiR; identified by match to protein family HMM PF05656 YP_001460714.1 yiiS; identified by match to protein family HMM PF04175; match to protein family HMM TIGR00743 YP_001460715.1 with UspC and Usp E is involved in resistance to UV radiation YP_001460716.1 identified by similarity to SP:P28861; match to protein family HMM PF00175; match to protein family HMM PF00970 YP_001460717.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_001460718.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_001460719.1 identified by similarity to SP:P31140; match to protein family HMM PF00230; match to protein family HMM TIGR00861 YP_001460720.1 identified by glimmer YP_001460721.1 yiiU; identified by match to protein family HMM PF06005 YP_001460722.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_001460723.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_001460724.1 heat shock protein involved in degradation of misfolded proteins YP_001460725.1 heat shock protein involved in degradation of misfolded proteins YP_001460726.1 identified by similarity to SP:P29131; match to protein family HMM PF05036; match to protein family HMM TIGR02223 YP_001460727.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins YP_001460728.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_001460729.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001460730.1 identified by match to protein family HMM TIGR02117 YP_001460731.1 member of the NlpC/P60 superfamily of peptidases YP_001460732.1 identified by glimmer YP_001460733.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_001460734.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine YP_001460735.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001460736.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_001460737.1 identified by similarity to SP:P13029; match to protein family HMM PF00141; match to protein family HMM TIGR00198 YP_001460738.1 yijE; identified by similarity to SP:P0ABT8; match to protein family HMM PF00892 YP_001460739.1 yijF; identified by similarity to GB:AAZ90633.1; match to protein family HMM PF06940 YP_001460740.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001460741.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone YP_001460742.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies YP_001460743.1 identified by similarity to SP:P32670; match to protein family HMM PF00359; match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417 YP_001460744.1 FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site YP_001460745.1 FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS YP_001460746.1 involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein YP_001460747.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494 YP_001460748.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog YP_001460749.1 identified by match to protein family HMM PF00165 YP_001460750.1 identified by match to protein family HMM PF00884 YP_001460751.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_001460752.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_001460753.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001460754.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001460755.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001460756.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA YP_001460757.1 catalyzes the conversion of NADPH to NADH YP_001460758.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_001460759.1 yijD; identified by match to protein family HMM PF07226 YP_001460760.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_001460761.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space YP_001460762.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001460763.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001460764.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_001460765.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_001460766.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001460767.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001460768.1 Modulates Rho-dependent transcription termination YP_001460769.1 binds directly to 23S ribosomal RNA YP_001460770.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001460771.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001460772.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001460773.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001460774.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001460775.1 identified by similarity to SP:P27375 YP_001460776.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_001460777.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_001460778.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate YP_001460779.1 identified by similarity to SP:P30138; match to protein family HMM PF00899; match to protein family HMM PF05237; match to protein family HMM TIGR02356 YP_001460780.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate YP_001460781.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001460782.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_001460783.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates YP_001460784.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001460785.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures YP_001460786.1 identified by similarity to SP:P32680; match to protein family HMM PF04222 YP_001460787.1 histone-like DNA-binding protein YP_001460788.1 yjaH; identified by match to protein family HMM PF07356 YP_001460789.1 identified by similarity to SP:P0AAA9 YP_001460790.1 identified by similarity to SP:P14377; match to protein family HMM PF00512; match to protein family HMM PF02518 YP_001460791.1 DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein YP_001460792.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001460793.1 involved in de novo purine biosynthesis YP_001460794.1 identified by glimmer YP_001460795.1 identified by match to protein family HMM PF00583 YP_001460796.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_001460797.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_001460798.1 identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346 YP_001460799.1 identified by glimmer YP_001460800.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol YP_001460801.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase YP_001460802.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_001460803.1 identified by match to protein family HMM PF02690; match to protein family HMM TIGR00704; match to protein family HMM TIGR01013 YP_001460804.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family YP_001460805.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA YP_001460806.1 yjbD; identified by similarity to GB:AAZ90700.1 YP_001460807.1 identified by match to protein family HMM PF01145 YP_001460808.1 identified by similarity to GB:CAD13753.1 YP_001460809.1 identified by match to protein family HMM PF06414 YP_001460810.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_001460811.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001460812.1 yjbE YP_001460813.1 yjbF YP_001460814.1 yjbG; identified by match to protein family HMM PF06251 YP_001460815.1 yjbH; identified by match to protein family HMM PF06082 YP_001460816.1 identified by similarity to GB:ABB68492.1 YP_001460817.1 yjbA; identified by match to protein family HMM PF06146 YP_001460818.1 xylose/proton symporter; member of the major facilitator superfamily (MFS) of transporter YP_001460819.1 with MalKFE is involved in the transport of maltose into the cell YP_001460820.1 with MalKGE is involved in maltose transport into the cell YP_001460821.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis YP_001460822.1 with malEFG is involved in import of maltose/maltodextrin YP_001460823.1 porin involved in the transport of maltose and maltodextrins YP_001460824.1 identified by match to protein family HMM PF07148 YP_001460825.1 yjbI YP_001460826.1 catalyzes the formation of 4-hydroxybenzoate from chorismate YP_001460827.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_001460828.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_001460829.1 identified by similarity to SP:P0ABN1; match to protein family HMM PF01219 YP_001460830.1 Represses a number of genes involved in the response to DNA damage YP_001460831.1 identified by similarity to SP:P28303; match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_001460832.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential YP_001460833.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB YP_001460834.1 identified by glimmer YP_001460835.1 identified by similarity to GB:AAZ90726.1 YP_001460836.1 identified by glimmer YP_001460837.1 yjbN; identified by similarity to SP:P32695; match to protein family HMM PF01207; match to protein family HMM TIGR00742 YP_001460838.1 identified by similarity to SP:P28304; match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001460839.1 unwinds double stranded DNA YP_001460840.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_001460841.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001460843.1 yjbQ; identified by match to protein family HMM PF01894; match to protein family HMM TIGR00149 YP_001460844.1 yjbR; identified by match to protein family HMM PF04237 YP_001460845.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_001460846.1 binds to single stranded DNA and PriA helcase facilitate replication restart YP_001460847.1 yjcB YP_001460848.1 yjcC; identified by match to protein family HMM PF00563 YP_001460849.1 regulates genes involved in response to oxidative stress YP_001460850.1 identified by match to protein family HMM PF00376; match to protein family HMM PF09278; match to protein family HMM TIGR01950 YP_001460851.1 identified by glimmer YP_001460852.1 yjcD; identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_001460853.1 identified by match to protein family HMM PF00999; match to protein family HMM TIGR00831 YP_001460854.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake YP_001460855.1 yjcH; identified by match to protein family HMM PF04341 YP_001460856.1 identified by glimmer YP_001460857.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001460858.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552 YP_001460859.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia YP_001460860.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR01409; match to protein family HMM TIGR03149 YP_001460861.1 identified by similarity to SP:P32709; match to protein family HMM PF03916; match to protein family HMM TIGR03148 YP_001460862.1 with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552 YP_001460863.1 identified by similarity to SP:P32711; match to protein family HMM PF03918; match to protein family HMM TIGR03147 YP_001460864.1 identified by similarity to SP:P32712; match to protein family HMM PF00515; match to protein family HMM PF07719 YP_001460865.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system YP_001460866.1 yjcO; identified by match to protein family HMM PF08238 YP_001460867.1 Selenoprotein. identified by similarity to SP:P07658; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01591 YP_001460868.1 part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family YP_001460869.1 possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_001460870.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_001460872.1 yjcS; identified by match to protein family HMM PF00753 YP_001460873.1 identified by glimmer YP_001460874.1 identified by match to protein family HMM PF02502 YP_001460875.1 identified by glimmer YP_001460876.1 required for the use of phosphonates and phosphite as phosphorus sources YP_001460877.1 PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role YP_001460878.1 identified by similarity to SP:P16690; match to protein family HMM TIGR02322 YP_001460879.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR02318 YP_001460880.1 identified by similarity to SP:P16679; match to protein family HMM PF00005; match to protein family HMM TIGR02324 YP_001460881.1 identified by similarity to SP:P16678; match to protein family HMM PF00005; match to protein family HMM TIGR02323 YP_001460882.1 identified by similarity to SP:P16688; match to protein family HMM PF06007 YP_001460883.1 identified by similarity to SP:P16687; match to protein family HMM PF05861 YP_001460884.1 identified by match to protein family HMM PF05845 YP_001460885.1 identified by similarity to SP:P16685; match to protein family HMM PF06754; match to protein family HMM TIGR03293 YP_001460886.1 may be involved in phosphonate uptake and biodegradation YP_001460887.1 identified by similarity to SP:P16683; match to protein family HMM PF00528; match to protein family HMM TIGR01097 YP_001460888.1 identified by similarity to SP:P16682; match to protein family HMM TIGR01098; match to protein family HMM TIGR03431 YP_001460889.1 identified by similarity to SP:P16677; match to protein family HMM PF00005; match to protein family HMM TIGR02315 YP_001460890.1 identified by similarity to SP:P16681; match to protein family HMM PF00903 YP_001460891.1 identified by match to protein family HMM PF03831; match to protein family HMM PF08274; match to protein family HMM TIGR00686 YP_001460893.1 yjcZ YP_001460894.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM PF08946; match to protein family HMM TIGR00883 YP_001460895.1 identified by similarity to SP:P30844; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_001460896.1 response regulator in two-component regulatory system with BasS YP_001460897.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division YP_001460898.1 identified by similarity to SP:P60061; match to protein family HMM PF00324 YP_001460899.1 identified by similarity to GB:AAB18143.1; match to protein family HMM PF00165 YP_001460900.1 identified by glimmer YP_001460901.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_001460902.1 identified by similarity to SP:P10411; match to protein family HMM PF00165 YP_001460903.1 identified by similarity to SP:P06720; match to protein family HMM PF02056 YP_001460904.1 identified by similarity to SP:P02921; match to protein family HMM TIGR00792 YP_001460905.1 yjdF YP_001460906.1 identified by similarity to SP:P14407; match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723 YP_001460907.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters YP_001460908.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration YP_001460909.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration YP_001460910.1 yjdI; identified by match to protein family HMM PF06902 YP_001460911.1 yjdJ YP_001460912.1 identified by similarity to GB:AAV77221.1 YP_001460913.1 class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001460914.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924 YP_001460915.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_001460916.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein YP_001460917.1 regulates the cadBA operon YP_001460918.1 yjdC; identified by match to protein family HMM PF00440 YP_001460919.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_001460920.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals YP_001460921.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_001460922.1 catalyzes the formation of fumarate from aspartate YP_001460923.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein YP_001460924.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function YP_001460925.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001460926.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001460927.1 yjeI YP_001460928.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001460929.1 yjeJ YP_001460930.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR00238 YP_001460931.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001460932.1 acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex YP_001460933.1 identified by similarity to SP:P0ADB7; match to protein family HMM PF08085 YP_001460934.1 member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations YP_001460935.1 lipocalin; globomycin-sensitive outer membrane lipoprotein YP_001460936.1 identified by match to protein family HMM PF00144 YP_001460937.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane YP_001460938.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001460939.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001460940.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001460941.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001460942.1 identified by match to protein family HMM PF00324 YP_001460943.1 identified by match to protein family HMM PF00924 YP_001460944.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_001460945.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_001460946.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_001460947.1 identified by match to protein family HMM PF00037; match to protein family HMM PF08331; match to protein family HMM TIGR00276 YP_001460948.1 identified by match to protein family HMM PF01256; match to protein family HMM PF03853; match to protein family HMM TIGR00196; match to protein family HMM TIGR00197 YP_001460949.1 possibly involved in cell wall synthesis YP_001460950.1 identified by match to protein family HMM PF01520 YP_001460951.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001460952.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001460953.1 Stimulates the elongation of poly(A) tails YP_001460954.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein YP_001460955.1 with HflC inhibits proteolysis of lambda cII protein by FtsH YP_001460956.1 with HflK inhibits proteolysis of lambda cII protein by FtsH YP_001460958.1 identified by glimmer YP_001460959.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001460960.1 negatively regulates the transcription of genes upregulated by nitrosative stress YP_001460961.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs YP_001460962.1 identified by glimmer YP_001460963.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_001460964.1 identified by similarity to GB:AAL23190.1 YP_001460965.1 identified by match to protein family HMM PF04012 YP_001460967.1 identified by match to protein family HMM PF03994 YP_001460968.1 identified by match to protein family HMM PF06693 YP_001460969.1 identified by match to protein family HMM PF03738 YP_001460970.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA YP_001460971.1 identified by match to protein family HMM PF07338 YP_001460972.1 identified by similarity to GB:ABB68688.1; match to protein family HMM PF07338 YP_001460973.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo YP_001460974.1 negative regulator of ulaG and ulaABCDEF YP_001460975.1 identified by similarity to SP:P39300 YP_001460976.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_001460977.1 identified by similarity to SP:P69822; match to protein family HMM PF02302 YP_001460978.1 identified by similarity to SP:P69820; match to protein family HMM PF00359 YP_001460979.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization YP_001460980.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway YP_001460981.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_001460982.1 identified by match to protein family HMM PF07338 YP_001460983.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001460984.1 binds single-stranded DNA at the primosome assembly site YP_001460985.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001460986.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001460987.1 identified by match to protein family HMM PF03480; match to protein family HMM TIGR00787 YP_001460988.1 identified by match to protein family HMM PF06808; match to protein family HMM TIGR00786 YP_001460989.1 identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF07992 YP_001460990.1 identified by match to protein family HMM PF01144 YP_001460991.1 identified by match to protein family HMM PF00378 YP_001460992.1 identified by match to protein family HMM PF01261 YP_001460993.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001460994.1 identified by match to protein family HMM PF00440 YP_001460995.1 identified by similarity to SP:P44415; match to protein family HMM PF04225; match to protein family HMM PF08525 YP_001460996.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides YP_001460997.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine YP_001460998.1 identified by glimmer YP_001460999.1 exported protein-like YP_001461000.1 identified by glimmer YP_001461001.1 identified by glimmer YP_001461002.1 Involved in anaerobic NO protection and iron metabolism YP_001461003.1 identified by similarity to SP:P39314; match to protein family HMM PF00892 YP_001461004.1 identified by match to protein family HMM PF01073; match to protein family HMM PF05368 YP_001461005.1 identified by match to protein family HMM PF01638 YP_001461006.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_001461007.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate YP_001461008.1 identified by match to protein family HMM TIGR01626 YP_001461009.1 identified by match to protein family HMM PF06526 YP_001461010.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_001461011.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001461012.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_001461013.1 ytfM; identified by match to protein family HMM PF01103; match to protein family HMM PF07244 YP_001461014.1 ytfN; identified by match to protein family HMM PF04357 YP_001461015.1 ytfP; identified by match to protein family HMM PF03674 YP_001461016.1 part of the toxin-antitoxin ChpB-ChpS system YP_001461017.1 toxin of the ChpB-ChpS toxin-antitoxin system YP_001461018.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001461019.1 identified by similarity to GB:AAN83745.1 YP_001461020.1 identified by match to protein family HMM PF00532 YP_001461021.1 identified by match to protein family HMM PF00005 YP_001461022.1 identified by match to protein family HMM PF02653 YP_001461023.1 membrane component of a sugar ABC transporter system YP_001461024.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_001461025.1 identified by similarity to SP:P37773; match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01081 YP_001461026.1 identified by match to protein family HMM PF04751 YP_001461027.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD YP_001461028.1 identified by similarity to SP:P0ABE7; match to protein family HMM PF07361 YP_001461029.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions YP_001461030.1 identified by glimmer YP_001461031.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_001461032.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403 YP_001461033.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001461034.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon YP_001461035.1 NULL; identified by glimmer YP_001461036.1 P-type ATPase involved in magnesium influx YP_001461037.1 identified by match to protein family HMM PF01548; match to protein family HMM PF02371 YP_001461038.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004 YP_001461039.1 involved in the allosteric regulation of aspartate carbamoyltransferase YP_001461040.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001461041.1 identified by match to protein family HMM PF08052 YP_001461042.1 identified by glimmer YP_001461043.1 identified by match to protein family HMM PF01042 YP_001461044.1 identified by match to protein family HMM PF00106 YP_001461045.1 yjgJ; identified by match to protein family HMM PF00440 YP_001461046.1 yjgK; identified by similarity to GB:CAD06928.1; match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_001461047.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III. YP_001461048.1 yjgD; identified by similarity to PDB:1NXI_A; match to protein family HMM PF06877 YP_001461049.1 NULL; identified by match to protein family HMM PF00583 YP_001461050.1 yjgN; identified by match to protein family HMM PF05987 YP_001461051.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001461052.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_001461053.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001461054.1 yjgP; identified by match to protein family HMM PF03739 YP_001461055.1 yjgQ; identified by match to protein family HMM PF03739 YP_001461056.1 yjgR; identified by match to protein family HMM PF05872 YP_001461057.1 identified by similarity to SP:P39343; match to protein family HMM PF00356; match to protein family HMM PF00532 YP_001461058.1 identified by similarity to SP:P39344; match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM PF06808; match to protein family HMM TIGR00791 YP_001461059.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate YP_001461060.1 NAD-binding YP_001461061.1 identified by similarity to SP:P39208; match to protein family HMM PF01202; match to protein family HMM TIGR01313 YP_001461062.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001461063.1 identified by match to protein family HMM PF00589 YP_001461064.1 identified by glimmer YP_001461065.1 identified by similarity to GB:AAP17067.1; match to protein family HMM PF00665 YP_001461066.1 identified by match to protein family HMM PF01527 YP_001461068.1 identified by match to protein family HMM PF07728 YP_001461070.1 yjhS; identified by match to protein family HMM PF03629 YP_001461071.1 yjhT; identified by match to protein family HMM PF01344; match to protein family HMM PF07646 YP_001461072.1 yjhA; identified by match to protein family HMM PF06178 YP_001461073.1 identified by glimmer YP_001461074.1 inversion of on/off regulator of fimA YP_001461075.1 inversion of on/off regulator of fimA YP_001461076.1 identified by similarity to SP:P04128; match to protein family HMM PF00419 YP_001461077.1 identified by similarity to SP:P04128; match to protein family HMM PF00419 YP_001461078.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_001461079.1 identified by similarity to SP:P30130; match to protein family HMM PF00577 YP_001461080.1 identified by similarity to SP:P08189; match to protein family HMM PF00419 YP_001461081.1 identified by similarity to SP:P08190; match to protein family HMM PF00419 YP_001461082.1 identified by match to protein family HMM PF00419; match to protein family HMM PF09160 YP_001461083.1 identified by similarity to SP:P0AC94; match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_001461084.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_001461085.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_001461086.1 identified by glimmer YP_001461087.1 regulates the expression of uxuBA YP_001461088.1 yjiC; identified by similarity to GB:ABB68791.1 YP_001461089.1 identified by glimmer YP_001461090.1 yjiD; identified by similarity to GB:AAL22004.1; match to protein family HMM PF04965 YP_001461091.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_001461092.1 identified by similarity to SP:P39377; match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR01975 YP_001461093.1 yjiG; identified by match to protein family HMM PF07670 YP_001461094.1 identified by match to protein family HMM PF07670 YP_001461095.1 in yeast cells this enzyme removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate; functions in tRNA splicing; the function and substrate of bacterial enzymes in organisms that do not perform splicing is unknown YP_001461096.1 identified by match to protein family HMM PF06779; match to protein family HMM PF07690 YP_001461097.1 yjiK; identified by match to protein family HMM PF06977 YP_001461098.1 identified by similarity to SP:P11568; match to protein family HMM PF01869; match to protein family HMM TIGR00241 YP_001461099.1 yjiM; identified by match to protein family HMM PF06050 YP_001461100.1 yjiN; identified by match to protein family HMM PF04286 YP_001461101.1 identified by similarity to SP:P39386; match to protein family HMM PF07690 YP_001461102.1 yjiP; identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_001461103.1 identified by glimmer YP_001461104.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_001461105.1 yjiS; identified by similarity to GB:BAB38726.1; match to protein family HMM PF06568 YP_001461106.1 NULL; identified by match to protein family HMM PF02492; match to protein family HMM PF07683 YP_001461107.1 yjiX; identified by similarity to SP:P0ADD1; match to protein family HMM PF04328 YP_001461108.1 identified by match to protein family HMM PF02554 YP_001461109.1 identified by similarity to SP:Q57501; match to protein family HMM PF01613; match to protein family HMM TIGR02296 YP_001461110.1 identified by similarity to SP:Q57160; match to protein family HMM PF03241; match to protein family HMM TIGR02310 YP_001461111.1 identified by match to protein family HMM PF00165; match to protein family HMM PF07883; match to protein family HMM TIGR02297 YP_001461112.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR02332 YP_001461113.1 identified by match to protein family HMM PF03328; match to protein family HMM TIGR02311 YP_001461114.1 identified by match to protein family HMM PF01689; match to protein family HMM TIGR02312 YP_001461115.1 identified by similarity to SP:Q05354; match to protein family HMM PF02962 YP_001461116.1 identified by match to protein family HMM PF02900; match to protein family HMM TIGR02298 YP_001461117.1 identified by match to protein family HMM PF00171; match to protein family HMM TIGR02299 YP_001461118.1 identified by match to protein family HMM PF01557; match to protein family HMM TIGR02303; match to protein family HMM TIGR02305 YP_001461119.1 identified by match to protein family HMM PF01047; match to protein family HMM TIGR02337 YP_001461120.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203 YP_001461121.1 identified by match to protein family HMM PF07690 YP_001461122.1 yjjM; identified by match to protein family HMM PF07729 YP_001461123.1 identified by glimmer YP_001461124.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_001461125.1 catalyzes the transfer of phosphoglycerol to the glucan backbone YP_001461126.1 identified by similarity to GB:AAZ90979.1 YP_001461127.1 acts to load the DnaB helicase onto the initiation site during DNA replication YP_001461128.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' YP_001461129.2 yjjB YP_001461130.1 identified by match to protein family HMM PF06738 YP_001461131.1 identified by glimmer YP_001461132.1 identified by match to protein family HMM PF00196 YP_001461133.1 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin YP_001461134.1 identified by similarity to SP:P39405; match to protein family HMM PF06276 YP_001461135.1 identified by similarity to GB:AAN83867.1; match to protein family HMM PF07256 YP_001461136.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit YP_001461137.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_001461138.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18 YP_001461139.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily YP_001461140.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_001461141.1 identified by similarity to SP:P27291; match to protein family HMM PF04972 YP_001461142.1 identified by glimmer YP_001461143.1 yjjU; identified by match to protein family HMM PF01734 YP_001461144.1 identified by match to protein family HMM PF01026 YP_001461145.1 identified by match to protein family HMM PF00037; match to protein family HMM PF04055 YP_001461146.1 yjjI YP_001461147.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_001461148.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_001461149.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_001461150.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_001461151.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins YP_001461153.1 catalyzes the formation of serine from O-phosphoserine YP_001461154.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001461155.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide YP_001461157.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001461158.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan YP_001461159.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription YP_001461160.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_001461161.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate YP_001461162.1 identified by similarity to SP:P0ACI2; match to protein family HMM PF00165; match to protein family HMM PF06445 YP_001461163.1 identified by match to protein family HMM PF05981 YP_001461164.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation YP_001461165.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation YP_001461166.1 identified by match to protein family HMM PF06123 YP_001461167.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_001461168.1 identified by similarity to GB:AAV80131.1 YP_001461169.1 member of the SPOUT superfamily of methyltransferases