-- dump date   	20140619_082321
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
585034000001	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
585034000002	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
585034000003	putative catalytic residues [active]
585034000004	putative nucleotide binding site [chemical binding]; other site
585034000005	putative aspartate binding site [chemical binding]; other site
585034000006	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
585034000007	dimer interface [polypeptide binding]; other site
585034000008	putative threonine allosteric regulatory site; other site
585034000009	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
585034000010	putative threonine allosteric regulatory site; other site
585034000011	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
585034000012	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
585034000013	homoserine kinase; Region: thrB; TIGR00191
585034000014	Protein of unknown function; Region: YhfT; pfam10797
585034000015	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
585034000016	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
585034000017	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
585034000018	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034000019	catalytic residue [active]
585034000020	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
585034000021	hypothetical protein; Validated; Region: PRK02101
585034000022	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
585034000023	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
585034000024	transaldolase-like protein; Provisional; Region: PTZ00411
585034000025	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
585034000026	active site
585034000027	dimer interface [polypeptide binding]; other site
585034000028	catalytic residue [active]
585034000029	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
585034000030	MPT binding site; other site
585034000031	trimer interface [polypeptide binding]; other site
585034000032	hypothetical protein; Provisional; Region: PRK10659
585034000033	hypothetical protein; Provisional; Region: PRK10236
585034000034	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
585034000035	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
585034000036	hypothetical protein; Provisional; Region: PRK10154
585034000037	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
585034000038	Nucleotide-binding domain of human HSPA9, Escherichia coli DnaK, and similar proteins; Region: HSPA9-like_NBD; cd11733
585034000039	nucleotide binding site [chemical binding]; other site
585034000040	NEF interaction site [polypeptide binding]; other site
585034000041	SBD interface [polypeptide binding]; other site
585034000042	chaperone protein DnaJ; Provisional; Region: PRK10767
585034000043	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
585034000044	HSP70 interaction site [polypeptide binding]; other site
585034000045	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
585034000046	substrate binding site [polypeptide binding]; other site
585034000047	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
585034000048	Zn binding sites [ion binding]; other site
585034000049	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
585034000050	dimer interface [polypeptide binding]; other site
585034000051	Hok/gef family; Region: HOK_GEF; pfam01848
585034000052	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
585034000053	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
585034000054	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034000055	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
585034000056	putative dimerization interface [polypeptide binding]; other site
585034000057	PapC C-terminal domain; Region: PapC_C; pfam13953
585034000058	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585034000059	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
585034000060	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
585034000061	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
585034000062	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
585034000063	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
585034000064	active site
585034000065	Riboflavin kinase; Region: Flavokinase; smart00904
585034000066	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
585034000067	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
585034000068	HIGH motif; other site
585034000069	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
585034000070	active site
585034000071	KMSKS motif; other site
585034000072	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
585034000073	tRNA binding surface [nucleotide binding]; other site
585034000074	anticodon binding site; other site
585034000075	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
585034000076	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
585034000077	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
585034000078	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
585034000079	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
585034000080	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
585034000081	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
585034000082	active site
585034000083	tetramer interface [polypeptide binding]; other site
585034000084	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
585034000085	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
585034000086	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
585034000087	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
585034000088	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
585034000089	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
585034000090	catalytic site [active]
585034000091	subunit interface [polypeptide binding]; other site
585034000092	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
585034000093	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
585034000094	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
585034000095	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
585034000096	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
585034000097	ATP-grasp domain; Region: ATP-grasp_4; cl17255
585034000098	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
585034000099	IMP binding site; other site
585034000100	dimer interface [polypeptide binding]; other site
585034000101	interdomain contacts; other site
585034000102	partial ornithine binding site; other site
585034000103	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
585034000104	carnitine operon protein CaiE; Provisional; Region: PRK13627
585034000105	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
585034000106	putative trimer interface [polypeptide binding]; other site
585034000107	putative metal binding site [ion binding]; other site
585034000108	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
585034000109	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
585034000110	substrate binding site [chemical binding]; other site
585034000111	oxyanion hole (OAH) forming residues; other site
585034000112	trimer interface [polypeptide binding]; other site
585034000113	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
585034000114	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
585034000115	acyl-activating enzyme (AAE) consensus motif; other site
585034000116	putative AMP binding site [chemical binding]; other site
585034000117	putative active site [active]
585034000118	putative CoA binding site [chemical binding]; other site
585034000119	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
585034000120	CoA-transferase family III; Region: CoA_transf_3; pfam02515
585034000121	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
585034000122	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
585034000123	active site
585034000124	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
585034000125	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
585034000126	Ligand binding site [chemical binding]; other site
585034000127	Electron transfer flavoprotein domain; Region: ETF; pfam01012
585034000128	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
585034000129	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF; cd01985
585034000130	Ligand binding site [chemical binding]; other site
585034000131	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
585034000132	putative oxidoreductase FixC; Provisional; Region: PRK10157
585034000133	ferredoxin-like protein FixX; Provisional; Region: PRK15449
585034000134	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034000135	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
585034000136	putative substrate translocation pore; other site
585034000137	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
585034000138	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
585034000139	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
585034000140	TrkA-N domain; Region: TrkA_N; pfam02254
585034000141	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
585034000142	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
585034000143	folate binding site [chemical binding]; other site
585034000144	NADP+ binding site [chemical binding]; other site
585034000145	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
585034000146	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
585034000147	active site
585034000148	metal binding site [ion binding]; metal-binding site
585034000149	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
585034000150	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
585034000151	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
585034000152	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
585034000153	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
585034000154	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
585034000155	SurA N-terminal domain; Region: SurA_N; pfam09312
585034000156	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
585034000157	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
585034000158	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
585034000159	OstA-like protein; Region: OstA; pfam03968
585034000160	Organic solvent tolerance protein; Region: OstA_C; pfam04453
585034000161	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
585034000162	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
585034000163	putative metal binding site [ion binding]; other site
585034000164	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
585034000165	HSP70 interaction site [polypeptide binding]; other site
585034000166	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
585034000167	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
585034000168	active site
585034000169	ATP-dependent helicase HepA; Validated; Region: PRK04914
585034000170	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585034000171	ATP binding site [chemical binding]; other site
585034000172	putative Mg++ binding site [ion binding]; other site
585034000173	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585034000174	nucleotide binding region [chemical binding]; other site
585034000175	ATP-binding site [chemical binding]; other site
585034000176	DNA polymerase II; Reviewed; Region: PRK05762
585034000177	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
585034000178	active site
585034000179	catalytic site [active]
585034000180	substrate binding site [chemical binding]; other site
585034000181	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
585034000182	active site
585034000183	metal-binding site
585034000184	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
585034000185	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
585034000186	intersubunit interface [polypeptide binding]; other site
585034000187	active site
585034000188	Zn2+ binding site [ion binding]; other site
585034000189	L-arabinose isomerase; Provisional; Region: PRK02929
585034000190	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
585034000191	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
585034000192	trimer interface [polypeptide binding]; other site
585034000193	putative substrate binding site [chemical binding]; other site
585034000194	putative metal binding site [ion binding]; other site
585034000195	ribulokinase; Provisional; Region: PRK04123
585034000196	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
585034000197	N- and C-terminal domain interface [polypeptide binding]; other site
585034000198	active site
585034000199	MgATP binding site [chemical binding]; other site
585034000200	catalytic site [active]
585034000201	metal binding site [ion binding]; metal-binding site
585034000202	carbohydrate binding site [chemical binding]; other site
585034000203	homodimer interface [polypeptide binding]; other site
585034000204	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
585034000205	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
585034000206	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034000207	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034000208	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
585034000209	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
585034000210	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
585034000211	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
585034000212	Walker A/P-loop; other site
585034000213	ATP binding site [chemical binding]; other site
585034000214	Q-loop/lid; other site
585034000215	ABC transporter signature motif; other site
585034000216	Walker B; other site
585034000217	D-loop; other site
585034000218	H-loop/switch region; other site
585034000219	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
585034000220	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034000221	dimer interface [polypeptide binding]; other site
585034000222	conserved gate region; other site
585034000223	putative PBP binding loops; other site
585034000224	ABC-ATPase subunit interface; other site
585034000225	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034000226	dimer interface [polypeptide binding]; other site
585034000227	conserved gate region; other site
585034000228	putative PBP binding loops; other site
585034000229	ABC-ATPase subunit interface; other site
585034000230	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
585034000231	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
585034000232	transcriptional regulator SgrR; Provisional; Region: PRK13626
585034000233	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
585034000234	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
585034000235	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034000236	sugar efflux transporter; Region: 2A0120; TIGR00899
585034000237	putative substrate translocation pore; other site
585034000238	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
585034000239	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
585034000240	substrate binding site [chemical binding]; other site
585034000241	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
585034000242	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
585034000243	substrate binding site [chemical binding]; other site
585034000244	ligand binding site [chemical binding]; other site
585034000245	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
585034000246	tartrate dehydrogenase; Region: TTC; TIGR02089
585034000247	2-isopropylmalate synthase; Validated; Region: PRK00915
585034000248	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
585034000249	active site
585034000250	catalytic residues [active]
585034000251	metal binding site [ion binding]; metal-binding site
585034000252	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
585034000253	leu operon leader peptide; Provisional; Region: PRK09925
585034000254	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
585034000255	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034000256	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
585034000257	putative substrate binding pocket [chemical binding]; other site
585034000258	putative dimerization interface [polypeptide binding]; other site
585034000259	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
585034000260	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
585034000261	PYR/PP interface [polypeptide binding]; other site
585034000262	dimer interface [polypeptide binding]; other site
585034000263	TPP binding site [chemical binding]; other site
585034000264	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
585034000265	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
585034000266	TPP-binding site [chemical binding]; other site
585034000267	dimer interface [polypeptide binding]; other site
585034000268	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
585034000269	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
585034000270	putative valine binding site [chemical binding]; other site
585034000271	dimer interface [polypeptide binding]; other site
585034000272	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
585034000273	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
585034000274	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585034000275	DNA binding site [nucleotide binding]
585034000276	domain linker motif; other site
585034000277	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
585034000278	dimerization interface [polypeptide binding]; other site
585034000279	ligand binding site [chemical binding]; other site
585034000280	mraZ protein; Region: TIGR00242
585034000281	MraZ protein; Region: MraZ; pfam02381
585034000282	MraZ protein; Region: MraZ; pfam02381
585034000283	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
585034000284	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
585034000285	cell division protein FtsL; Provisional; Region: PRK10772
585034000286	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
585034000287	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
585034000288	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
585034000289	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
585034000290	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
585034000291	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
585034000292	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
585034000293	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
585034000294	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
585034000295	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
585034000296	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
585034000297	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
585034000298	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
585034000299	Mg++ binding site [ion binding]; other site
585034000300	putative catalytic motif [active]
585034000301	putative substrate binding site [chemical binding]; other site
585034000302	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
585034000303	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
585034000304	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
585034000305	cell division protein FtsW; Provisional; Region: PRK10774
585034000306	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
585034000307	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
585034000308	active site
585034000309	homodimer interface [polypeptide binding]; other site
585034000310	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
585034000311	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
585034000312	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
585034000313	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
585034000314	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
585034000315	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
585034000316	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
585034000317	cell division protein FtsQ; Provisional; Region: PRK10775
585034000318	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
585034000319	Cell division protein FtsQ; Region: FtsQ; pfam03799
585034000320	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
585034000321	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
585034000322	Cell division protein FtsA; Region: FtsA; pfam14450
585034000323	cell division protein FtsZ; Validated; Region: PRK09330
585034000324	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
585034000325	nucleotide binding site [chemical binding]; other site
585034000326	SulA interaction site; other site
585034000327	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
585034000328	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
585034000329	SecA regulator SecM; Provisional; Region: PRK02943
585034000330	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
585034000331	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
585034000332	SEC-C motif; Region: SEC-C; pfam02810
585034000333	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
585034000334	active site
585034000335	8-oxo-dGMP binding site [chemical binding]; other site
585034000336	nudix motif; other site
585034000337	metal binding site [ion binding]; metal-binding site
585034000338	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
585034000339	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
585034000340	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
585034000341	CoA-binding site [chemical binding]; other site
585034000342	ATP-binding [chemical binding]; other site
585034000343	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
585034000344	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
585034000345	active site
585034000346	type IV pilin biogenesis protein; Provisional; Region: PRK10573
585034000347	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
585034000348	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
585034000349	hypothetical protein; Provisional; Region: PRK10436
585034000350	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
585034000351	Walker A motif; other site
585034000352	ATP binding site [chemical binding]; other site
585034000353	Walker B motif; other site
585034000354	putative major pilin subunit; Provisional; Region: PRK10574
585034000355	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
585034000356	Pilin (bacterial filament); Region: Pilin; pfam00114
585034000357	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
585034000358	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
585034000359	dimerization interface [polypeptide binding]; other site
585034000360	active site
585034000361	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
585034000362	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
585034000363	amidase catalytic site [active]
585034000364	Zn binding residues [ion binding]; other site
585034000365	substrate binding site [chemical binding]; other site
585034000366	regulatory protein AmpE; Provisional; Region: PRK10987
585034000367	aromatic amino acid transporter; Provisional; Region: PRK10238
585034000368	Transcriptional regulators [Transcription]; Region: FadR; COG2186
585034000369	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034000370	DNA-binding site [nucleotide binding]; DNA binding site
585034000371	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
585034000372	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
585034000373	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
585034000374	dimer interface [polypeptide binding]; other site
585034000375	TPP-binding site [chemical binding]; other site
585034000376	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
585034000377	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
585034000378	E3 interaction surface; other site
585034000379	lipoyl attachment site [posttranslational modification]; other site
585034000380	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
585034000381	E3 interaction surface; other site
585034000382	lipoyl attachment site [posttranslational modification]; other site
585034000383	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
585034000384	E3 interaction surface; other site
585034000385	lipoyl attachment site [posttranslational modification]; other site
585034000386	e3 binding domain; Region: E3_binding; pfam02817
585034000387	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
585034000388	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
585034000389	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
585034000390	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585034000391	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
585034000392	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
585034000393	Protein of unknown function (DUF3106); Region: DUF3106; pfam11304
585034000394	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
585034000395	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
585034000396	substrate binding site [chemical binding]; other site
585034000397	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
585034000398	substrate binding site [chemical binding]; other site
585034000399	ligand binding site [chemical binding]; other site
585034000400	hypothetical protein; Provisional; Region: PRK05248
585034000401	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
585034000402	spermidine synthase; Provisional; Region: PRK00811
585034000403	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034000404	S-adenosylmethionine binding site [chemical binding]; other site
585034000405	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
585034000406	multicopper oxidase; Provisional; Region: PRK10965
585034000407	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
585034000408	Multicopper oxidase; Region: Cu-oxidase; pfam00394
585034000409	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
585034000410	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
585034000411	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
585034000412	Trp docking motif [polypeptide binding]; other site
585034000413	putative active site [active]
585034000414	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
585034000415	active site
585034000416	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
585034000417	active site clefts [active]
585034000418	zinc binding site [ion binding]; other site
585034000419	dimer interface [polypeptide binding]; other site
585034000420	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
585034000421	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
585034000422	Walker A/P-loop; other site
585034000423	ATP binding site [chemical binding]; other site
585034000424	Q-loop/lid; other site
585034000425	ABC transporter signature motif; other site
585034000426	Walker B; other site
585034000427	D-loop; other site
585034000428	H-loop/switch region; other site
585034000429	inner membrane transport permease; Provisional; Region: PRK15066
585034000430	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
585034000431	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
585034000432	active pocket/dimerization site; other site
585034000433	active site
585034000434	phosphorylation site [posttranslational modification]
585034000435	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
585034000436	putative active site [active]
585034000437	putative metal binding site [ion binding]; other site
585034000438	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
585034000439	tetramerization interface [polypeptide binding]; other site
585034000440	active site
585034000441	Uncharacterized conserved protein [Function unknown]; Region: COG5464
585034000442	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
585034000443	pantoate--beta-alanine ligase; Region: panC; TIGR00018
585034000444	Pantoate-beta-alanine ligase; Region: PanC; cd00560
585034000445	active site
585034000446	ATP-binding site [chemical binding]; other site
585034000447	pantoate-binding site; other site
585034000448	HXXH motif; other site
585034000449	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
585034000450	oligomerization interface [polypeptide binding]; other site
585034000451	active site
585034000452	metal binding site [ion binding]; metal-binding site
585034000453	putative fimbrial-like adhesin protein; Provisional; Region: PRK09723
585034000454	putative fimbrial protein StaF; Provisional; Region: PRK15262
585034000455	putative fimbrial protein StaE; Provisional; Region: PRK15263
585034000456	Fimbrial protein; Region: Fimbrial; cl01416
585034000457	putative fimbrial outer membrane usher protein; Provisional; Region: PRK09828
585034000458	PapC N-terminal domain; Region: PapC_N; pfam13954
585034000459	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585034000460	PapC C-terminal domain; Region: PapC_C; pfam13953
585034000461	putative chaperone protein EcpD; Provisional; Region: PRK09926
585034000462	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585034000463	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
585034000464	Fimbrial protein; Region: Fimbrial; cl01416
585034000465	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
585034000466	catalytic center binding site [active]
585034000467	ATP binding site [chemical binding]; other site
585034000468	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
585034000469	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
585034000470	active site
585034000471	NTP binding site [chemical binding]; other site
585034000472	metal binding triad [ion binding]; metal-binding site
585034000473	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
585034000474	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
585034000475	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
585034000476	tRNA synthetases class I (E and Q), catalytic domain; Region: tRNA-synt_1c; pfam00749
585034000477	active site
585034000478	nucleotide binding site [chemical binding]; other site
585034000479	HIGH motif; other site
585034000480	KMSKS motif; other site
585034000481	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
585034000482	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
585034000483	2'-5' RNA ligase; Provisional; Region: PRK15124
585034000484	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
585034000485	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
585034000486	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
585034000487	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585034000488	ATP binding site [chemical binding]; other site
585034000489	putative Mg++ binding site [ion binding]; other site
585034000490	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585034000491	nucleotide binding region [chemical binding]; other site
585034000492	ATP-binding site [chemical binding]; other site
585034000493	Helicase associated domain (HA2) Add an annotation; Region: HA2; smart00847
585034000494	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
585034000495	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
585034000496	Transglycosylase; Region: Transgly; pfam00912
585034000497	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
585034000498	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
585034000499	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585034000500	N-terminal plug; other site
585034000501	ligand-binding site [chemical binding]; other site
585034000502	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
585034000503	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
585034000504	Walker A/P-loop; other site
585034000505	ATP binding site [chemical binding]; other site
585034000506	Q-loop/lid; other site
585034000507	ABC transporter signature motif; other site
585034000508	Walker B; other site
585034000509	D-loop; other site
585034000510	H-loop/switch region; other site
585034000511	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
585034000512	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
585034000513	siderophore binding site; other site
585034000514	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
585034000515	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
585034000516	ABC-ATPase subunit  interface; other site
585034000517	dimer interface [polypeptide binding]; other site
585034000518	putative PBP binding regions; other site
585034000519	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
585034000520	ABC-ATPase subunit  interface; other site
585034000521	dimer interface [polypeptide binding]; other site
585034000522	putative PBP binding regions; other site
585034000523	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
585034000524	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
585034000525	inhibitor-cofactor binding pocket; inhibition site
585034000526	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034000527	catalytic residue [active]
585034000528	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
585034000529	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
585034000530	Cl- selectivity filter; other site
585034000531	Cl- binding residues [ion binding]; other site
585034000532	pore gating glutamate residue; other site
585034000533	dimer interface [polypeptide binding]; other site
585034000534	H+/Cl- coupling transport residue; other site
585034000535	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
585034000536	hypothetical protein; Provisional; Region: PRK10578
585034000537	UPF0126 domain; Region: UPF0126; pfam03458
585034000538	UPF0126 domain; Region: UPF0126; pfam03458
585034000539	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
585034000540	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
585034000541	cobalamin binding residues [chemical binding]; other site
585034000542	putative BtuC binding residues; other site
585034000543	dimer interface [polypeptide binding]; other site
585034000544	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
585034000545	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
585034000546	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
585034000547	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
585034000548	Zn2+ binding site [ion binding]; other site
585034000549	Mg2+ binding site [ion binding]; other site
585034000550	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
585034000551	serine endoprotease; Provisional; Region: PRK10942
585034000552	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
585034000553	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
585034000554	protein binding site [polypeptide binding]; other site
585034000555	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
585034000556	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
585034000557	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
585034000558	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
585034000559	hypothetical protein; Provisional; Region: PRK13677
585034000560	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
585034000561	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
585034000562	trimer interface [polypeptide binding]; other site
585034000563	active site
585034000564	substrate binding site [chemical binding]; other site
585034000565	CoA binding site [chemical binding]; other site
585034000566	PII uridylyl-transferase; Provisional; Region: PRK05007
585034000567	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
585034000568	metal binding triad; other site
585034000569	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
585034000570	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
585034000571	Zn2+ binding site [ion binding]; other site
585034000572	Mg2+ binding site [ion binding]; other site
585034000573	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
585034000574	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
585034000575	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
585034000576	active site
585034000577	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
585034000578	rRNA interaction site [nucleotide binding]; other site
585034000579	S8 interaction site; other site
585034000580	putative laminin-1 binding site; other site
585034000581	elongation factor Ts; Provisional; Region: tsf; PRK09377
585034000582	UBA/TS-N domain; Region: UBA; pfam00627
585034000583	Elongation factor TS; Region: EF_TS; pfam00889
585034000584	Elongation factor TS; Region: EF_TS; pfam00889
585034000585	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
585034000586	putative nucleotide binding site [chemical binding]; other site
585034000587	uridine monophosphate binding site [chemical binding]; other site
585034000588	homohexameric interface [polypeptide binding]; other site
585034000589	ribosome recycling factor; Reviewed; Region: frr; PRK00083
585034000590	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
585034000591	hinge region; other site
585034000592	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
585034000593	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
585034000594	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
585034000595	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
585034000596	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
585034000597	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
585034000598	catalytic residue [active]
585034000599	putative FPP diphosphate  binding site; other site
585034000600	putative FPP binding hydrophobic cleft; other site
585034000601	dimer interface [polypeptide binding]; other site
585034000602	putative IPP diphosphate binding site; other site
585034000603	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
585034000604	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
585034000605	zinc metallopeptidase RseP; Provisional; Region: PRK10779
585034000606	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
585034000607	active site
585034000608	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
585034000609	protein binding site [polypeptide binding]; other site
585034000610	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
585034000611	putative substrate binding region [chemical binding]; other site
585034000612	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
585034000613	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
585034000614	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
585034000615	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
585034000616	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
585034000617	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
585034000618	Surface antigen; Region: Bac_surface_Ag; pfam01103
585034000619	periplasmic chaperone; Provisional; Region: PRK10780
585034000620	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
585034000621	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
585034000622	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
585034000623	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
585034000624	trimer interface [polypeptide binding]; other site
585034000625	active site
585034000626	UDP-GlcNAc binding site [chemical binding]; other site
585034000627	lipid binding site [chemical binding]; lipid-binding site
585034000628	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
585034000629	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
585034000630	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
585034000631	active site
585034000632	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
585034000633	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
585034000634	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
585034000635	RNA/DNA hybrid binding site [nucleotide binding]; other site
585034000636	active site
585034000637	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
585034000638	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
585034000639	putative active site [active]
585034000640	putative PHP Thumb interface [polypeptide binding]; other site
585034000641	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
585034000642	generic binding surface II; other site
585034000643	generic binding surface I; other site
585034000644	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
585034000645	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
585034000646	lysine decarboxylase LdcC; Provisional; Region: PRK15399
585034000647	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
585034000648	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
585034000649	homodimer interface [polypeptide binding]; other site
585034000650	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034000651	catalytic residue [active]
585034000652	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
585034000653	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
585034000654	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
585034000655	putative metal binding site [ion binding]; other site
585034000656	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
585034000657	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
585034000658	Ligand Binding Site [chemical binding]; other site
585034000659	TilS substrate binding domain; Region: TilS; pfam09179
585034000660	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
585034000661	Rho-binding antiterminator; Provisional; Region: PRK11625
585034000662	hypothetical protein; Provisional; Region: PRK04964
585034000663	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
585034000664	hypothetical protein; Provisional; Region: PRK09256
585034000665	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
585034000666	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
585034000667	NlpE N-terminal domain; Region: NlpE; pfam04170
585034000668	fragment of putative lipoprotein (part 2);Evidence 7 : Gene remnant; Product type lp : lipoprotein
585034000669	fragment of putative lipoprotein (part 1);Evidence 7 : Gene remnant; Product type lp : lipoprotein
585034000670	prolyl-tRNA synthetase; Provisional; Region: PRK09194
585034000671	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
585034000672	dimer interface [polypeptide binding]; other site
585034000673	motif 1; other site
585034000674	active site
585034000675	motif 2; other site
585034000676	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
585034000677	putative deacylase active site [active]
585034000678	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
585034000679	active site
585034000680	motif 3; other site
585034000681	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
585034000682	anticodon binding site; other site
585034000683	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
585034000684	homodimer interaction site [polypeptide binding]; other site
585034000685	cofactor binding site; other site
585034000686	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
585034000687	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
585034000688	lipoprotein, YaeC family; Region: TIGR00363
585034000689	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034000690	dimer interface [polypeptide binding]; other site
585034000691	conserved gate region; other site
585034000692	ABC-ATPase subunit interface; other site
585034000693	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
585034000694	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
585034000695	Walker A/P-loop; other site
585034000696	ATP binding site [chemical binding]; other site
585034000697	Q-loop/lid; other site
585034000698	ABC transporter signature motif; other site
585034000699	Walker B; other site
585034000700	D-loop; other site
585034000701	H-loop/switch region; other site
585034000702	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
585034000703	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
585034000704	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034000705	active site
585034000706	motif I; other site
585034000707	motif II; other site
585034000708	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
585034000709	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
585034000710	active site
585034000711	catalytic tetrad [active]
585034000712	Transcriptional regulator [Transcription]; Region: LysR; COG0583
585034000713	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034000714	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
585034000715	putative effector binding pocket; other site
585034000716	dimerization interface [polypeptide binding]; other site
585034000717	hypothetical protein; Provisional; Region: PRK05421
585034000718	putative catalytic site [active]
585034000719	putative metal binding site [ion binding]; other site
585034000720	putative phosphate binding site [ion binding]; other site
585034000721	putative catalytic site [active]
585034000722	putative phosphate binding site [ion binding]; other site
585034000723	putative metal binding site [ion binding]; other site
585034000724	Methyltransferase domain; Region: Methyltransf_31; pfam13847
585034000725	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034000726	S-adenosylmethionine binding site [chemical binding]; other site
585034000727	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
585034000728	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
585034000729	N-acetyl-D-glucosamine binding site [chemical binding]; other site
585034000730	catalytic residue [active]
585034000731	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
585034000732	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
585034000733	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
585034000734	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034000735	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
585034000736	RNA/DNA hybrid binding site [nucleotide binding]; other site
585034000737	active site
585034000738	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
585034000739	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
585034000740	active site
585034000741	catalytic site [active]
585034000742	substrate binding site [chemical binding]; other site
585034000743	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
585034000744	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
585034000745	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
585034000746	ImpA domain protein; Region: DUF3702; pfam12486
585034000747	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
585034000748	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
585034000749	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
585034000750	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
585034000751	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
585034000752	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
585034000753	type VI secretion-associated protein, VC_A0118 family; Region: VI_minor_1; TIGR03360
585034000754	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
585034000755	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034000756	Walker A motif; other site
585034000757	ATP binding site [chemical binding]; other site
585034000758	Walker B motif; other site
585034000759	arginine finger; other site
585034000760	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034000761	Walker A motif; other site
585034000762	ATP binding site [chemical binding]; other site
585034000763	Walker B motif; other site
585034000764	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
585034000765	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
585034000766	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
585034000767	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
585034000768	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3521
585034000769	Predicted component of the type VI protein secretion system, contains a FHA domain [Intracellular trafficking, secretion, and vesicular    transport; Signal transduction mechanisms]; Region: COG3456
585034000770	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
585034000771	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
585034000772	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
585034000773	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
585034000774	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
585034000775	Protein of unknown function (DUF877); Region: DUF877; pfam05943
585034000776	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
585034000777	Protein of unknown function (DUF770); Region: DUF770; pfam05591
585034000778	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
585034000779	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
585034000780	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
585034000781	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
585034000782	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
585034000783	PAAR motif; Region: PAAR_motif; cl15808
585034000784	RHS Repeat; Region: RHS_repeat; pfam05593
585034000785	RHS Repeat; Region: RHS_repeat; pfam05593
585034000786	RHS Repeat; Region: RHS_repeat; cl11982
585034000787	RHS Repeat; Region: RHS_repeat; cl11982
585034000788	RHS Repeat; Region: RHS_repeat; cl11982
585034000789	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
585034000790	RHS Repeat; Region: RHS_repeat; pfam05593
585034000791	RHS Repeat; Region: RHS_repeat; cl11982
585034000792	RHS Repeat; Region: RHS_repeat; pfam05593
585034000793	RHS Repeat; Region: RHS_repeat; cl11982
585034000794	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
585034000795	RHS protein; Region: RHS; pfam03527
585034000796	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
585034000797	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
585034000798	fragment of putative transposase (partial);Evidence 7 : Gene remnant; Product type ph : phenotype
585034000799	Transposase [DNA replication, recombination, and repair]; Region: COG5433
585034000800	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
585034000801	Transposase [DNA replication, recombination, and repair]; Region: COG5433
585034000802	Transposase [DNA replication, recombination, and repair]; Region: COG5433
585034000803	Protein of unknown function (DUF3969); Region: DUF3969; pfam13108
585034000804	PAAR motif; Region: PAAR_motif; cl15808
585034000805	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
585034000806	RHS Repeat; Region: RHS_repeat; pfam05593
585034000807	RHS Repeat; Region: RHS_repeat; pfam05593
585034000808	RHS Repeat; Region: RHS_repeat; pfam05593
585034000809	RHS Repeat; Region: RHS_repeat; cl11982
585034000810	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
585034000811	RHS Repeat; Region: RHS_repeat; pfam05593
585034000812	RHS Repeat; Region: RHS_repeat; cl11982
585034000813	RHS Repeat; Region: RHS_repeat; pfam05593
585034000814	RHS protein; Region: RHS; pfam03527
585034000815	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
585034000816	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
585034000817	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
585034000818	Transposase [DNA replication, recombination, and repair]; Region: COG5433
585034000819	Transposase [DNA replication, recombination, and repair]; Region: COG5433
585034000820	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
585034000821	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
585034000822	Transposase [DNA replication, recombination, and repair]; Region: COG5433
585034000823	Transposase [DNA replication, recombination, and repair]; Region: COG5433
585034000824	C-N hydrolase family amidase; Provisional; Region: PRK10438
585034000825	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
585034000826	putative active site [active]
585034000827	catalytic triad [active]
585034000828	dimer interface [polypeptide binding]; other site
585034000829	multimer interface [polypeptide binding]; other site
585034000830	C-lysozyme inhibitor; Provisional; Region: PRK09993
585034000831	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
585034000832	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
585034000833	active site
585034000834	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
585034000835	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
585034000836	dimer interface [polypeptide binding]; other site
585034000837	active site
585034000838	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
585034000839	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
585034000840	putative active site [active]
585034000841	putative dimer interface [polypeptide binding]; other site
585034000842	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
585034000843	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
585034000844	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
585034000845	RelB antitoxin; Region: RelB; cl01171
585034000846	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
585034000847	NlpC/P60 family; Region: NLPC_P60; pfam00877
585034000848	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
585034000849	HicB family; Region: HicB; pfam05534
585034000850	Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; COG1298
585034000851	FHIPEP family; Region: FHIPEP; pfam00771
585034000852	hypothetical protein; Validated; Region: PRK06778
585034000853	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
585034000854	ligand binding site [chemical binding]; other site
585034000855	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
585034000856	active site
585034000857	DNA polymerase IV; Validated; Region: PRK02406
585034000858	DNA binding site [nucleotide binding]
585034000859	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
585034000860	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585034000861	Coenzyme A binding pocket [chemical binding]; other site
585034000862	hypothetical protein; Reviewed; Region: PRK09588
585034000863	release factor H-coupled RctB family protein; Region: release_rtcB; TIGR03073
585034000864	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
585034000865	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
585034000866	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
585034000867	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
585034000868	metal binding site [ion binding]; metal-binding site
585034000869	dimer interface [polypeptide binding]; other site
585034000870	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
585034000871	active site
585034000872	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
585034000873	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
585034000874	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
585034000875	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
585034000876	trimer interface [polypeptide binding]; other site
585034000877	eyelet of channel; other site
585034000878	gamma-glutamyl kinase; Provisional; Region: PRK05429
585034000879	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
585034000880	nucleotide binding site [chemical binding]; other site
585034000881	homotetrameric interface [polypeptide binding]; other site
585034000882	putative phosphate binding site [ion binding]; other site
585034000883	putative allosteric binding site; other site
585034000884	PUA domain; Region: PUA; pfam01472
585034000885	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
585034000886	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
585034000887	putative catalytic cysteine [active]
585034000888	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
585034000889	Transcriptional regulator [Transcription]; Region: LysR; COG0583
585034000890	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
585034000891	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
585034000892	XdhC Rossmann domain; Region: XdhC_C; pfam13478
585034000893	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
585034000894	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
585034000895	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
585034000896	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
585034000897	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; smart01092
585034000898	aldehyde oxidoreductase 2Fe-2S subunit; Provisional; Region: PRK11433
585034000899	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
585034000900	catalytic loop [active]
585034000901	iron binding site [ion binding]; other site
585034000902	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
585034000903	Predicted periplasmic/secreted protein [Function unknown]; Region: COG3477
585034000904	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585034000905	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
585034000906	putative fimbrial protein TcfA; Provisional; Region: PRK15308
585034000907	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
585034000908	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585034000909	DNA binding residues [nucleotide binding]
585034000910	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
585034000911	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
585034000912	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
585034000913	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
585034000914	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
585034000915	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
585034000916	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
585034000917	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034000918	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
585034000919	Predicted membrane protein [Function unknown]; Region: COG3059
585034000920	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
585034000921	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
585034000922	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
585034000923	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585034000924	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
585034000925	Cupin; Region: Cupin_6; pfam12852
585034000926	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
585034000927	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034000928	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
585034000929	Cysteine-rich domain; Region: CCG; pfam02754
585034000930	Cysteine-rich domain; Region: CCG; pfam02754
585034000931	iron-sulfur cluster-binding protein; Region: TIGR00273
585034000932	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
585034000933	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
585034000934	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
585034000935	Uncharacterized conserved protein [Function unknown]; Region: COG1556
585034000936	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
585034000937	choline dehydrogenase; Validated; Region: PRK02106
585034000938	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
585034000939	betaine aldehyde dehydrogenase; Provisional; Region: PRK13252
585034000940	NAD+-dependent 4-trimethylaminobutyraldehyde dehydrogenase, ALDH family 9A1; Region: ALDH_F9_TMBADH; cd07090
585034000941	tetrameric interface [polypeptide binding]; other site
585034000942	NAD binding site [chemical binding]; other site
585034000943	catalytic residues [active]
585034000944	transcriptional regulator BetI; Validated; Region: PRK00767
585034000945	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585034000946	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
585034000947	choline transport protein BetT; Provisional; Region: PRK09928
585034000948	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
585034000949	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
585034000950	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
585034000951	Autotransporter beta-domain; Region: Autotransporter; pfam03797
585034000952	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585034000953	DNA binding residues [nucleotide binding]
585034000954	dimerization interface [polypeptide binding]; other site
585034000955	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585034000956	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
585034000957	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034000958	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
585034000959	dimerization interface [polypeptide binding]; other site
585034000960	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
585034000961	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
585034000962	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
585034000963	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
585034000964	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
585034000965	Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Region: SucD; COG0074
585034000966	CoA binding domain; Region: CoA_binding; pfam02629
585034000967	CoA-ligase; Region: Ligase_CoA; pfam00549
585034000968	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
585034000969	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
585034000970	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
585034000971	putative substrate binding site [chemical binding]; other site
585034000972	nucleotide binding site [chemical binding]; other site
585034000973	nucleotide binding site [chemical binding]; other site
585034000974	homodimer interface [polypeptide binding]; other site
585034000975	putative deaminase; Validated; Region: PRK06846
585034000976	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
585034000977	active site
585034000978	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
585034000979	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
585034000980	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
585034000981	ligand binding site [chemical binding]; other site
585034000982	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
585034000983	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
585034000984	Walker A/P-loop; other site
585034000985	ATP binding site [chemical binding]; other site
585034000986	Q-loop/lid; other site
585034000987	ABC transporter signature motif; other site
585034000988	Walker B; other site
585034000989	D-loop; other site
585034000990	H-loop/switch region; other site
585034000991	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
585034000992	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585034000993	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585034000994	TM-ABC transporter signature motif; other site
585034000995	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585034000996	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585034000997	TM-ABC transporter signature motif; other site
585034000998	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
585034000999	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
585034001000	putative NAD(P) binding site [chemical binding]; other site
585034001001	putative substrate binding site [chemical binding]; other site
585034001002	catalytic Zn binding site [ion binding]; other site
585034001003	structural Zn binding site [ion binding]; other site
585034001004	dimer interface [polypeptide binding]; other site
585034001005	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
585034001006	hypothetical protein; Provisional; Region: PRK09929
585034001007	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
585034001008	Propionate catabolism activator; Region: PrpR_N; pfam06506
585034001009	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034001010	Walker A motif; other site
585034001011	ATP binding site [chemical binding]; other site
585034001012	Walker B motif; other site
585034001013	arginine finger; other site
585034001014	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
585034001015	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
585034001016	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
585034001017	tetramer interface [polypeptide binding]; other site
585034001018	active site
585034001019	Mg2+/Mn2+ binding site [ion binding]; other site
585034001020	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
585034001021	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
585034001022	dimer interface [polypeptide binding]; other site
585034001023	active site
585034001024	citrylCoA binding site [chemical binding]; other site
585034001025	oxalacetate/citrate binding site [chemical binding]; other site
585034001026	coenzyme A binding site [chemical binding]; other site
585034001027	catalytic triad [active]
585034001028	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
585034001029	2-methylcitrate dehydratase; Region: prpD; TIGR02330
585034001030	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
585034001031	Propionyl-CoA synthetase (PrpE); Region: PrpE; cd05967
585034001032	acyl-activating enzyme (AAE) consensus motif; other site
585034001033	putative AMP binding site [chemical binding]; other site
585034001034	putative active site [active]
585034001035	putative CoA binding site [chemical binding]; other site
585034001036	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
585034001037	Transposase; Region: DEDD_Tnp_IS110; pfam01548
585034001038	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
585034001039	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
585034001040	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
585034001041	Na binding site [ion binding]; other site
585034001042	putative substrate binding site [chemical binding]; other site
585034001043	cytosine deaminase; Provisional; Region: PRK09230
585034001044	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
585034001045	active site
585034001046	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
585034001047	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034001048	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator CynR, contains the type 2 periplasmic binding fold; Region: PBP2_CynR; cd08425
585034001049	dimerization interface [polypeptide binding]; other site
585034001050	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
585034001051	active site clefts [active]
585034001052	zinc binding site [ion binding]; other site
585034001053	dimer interface [polypeptide binding]; other site
585034001054	Cyanate lyase [Inorganic ion transport and metabolism]; Region: CynS; COG1513
585034001055	Cyanase C-terminal domain. Cyanase (Cyanate lyase) is responsible for the hydrolysis of cyanate.  It catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. This allows organisms that possess the enzyme to overcome the...; Region: Cyanase_C; cd00559
585034001056	oligomer interface [polypeptide binding]; other site
585034001057	active site
585034001058	putative cyanate transporter; Provisional; Region: cynX; PRK09705
585034001059	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034001060	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
585034001061	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034001062	putative substrate translocation pore; other site
585034001063	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
585034001064	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
585034001065	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
585034001066	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
585034001067	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
585034001068	lac repressor; Reviewed; Region: lacI; PRK09526
585034001069	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585034001070	DNA binding site [nucleotide binding]
585034001071	domain linker motif; other site
585034001072	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
585034001073	ligand binding site [chemical binding]; other site
585034001074	dimerization interface (open form) [polypeptide binding]; other site
585034001075	dimerization interface (closed form) [polypeptide binding]; other site
585034001076	DNA-binding transcriptional activator MhpR; Provisional; Region: PRK09834
585034001077	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
585034001078	Bacterial transcriptional regulator; Region: IclR; pfam01614
585034001079	3-(3-hydroxyphenyl)propionate hydroxylase; Validated; Region: mhpA; PRK06183
585034001080	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
585034001081	Subunit B of the Class III Extradiol ring-cleavage dioxygenase, 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB), which catalyzes the oxidization and subsequent ring-opening of 2,3-dihydroxyphenylpropionate; Region: MhpB_like; cd07365
585034001082	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
585034001083	putative active site [active]
585034001084	Fe(II) binding site [ion binding]; other site
585034001085	putative dimer interface [polypeptide binding]; other site
585034001086	putative tetramer interface [polypeptide binding]; other site
585034001087	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; Region: biphenyl_bphD; TIGR03343
585034001088	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
585034001089	nucleophilic elbow; other site
585034001090	catalytic triad; other site
585034001091	2-keto-4-pentenoate hydratase; Provisional; Region: mhpD; PRK11342
585034001092	acetaldehyde dehydrogenase; Validated; Region: PRK08300
585034001093	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
585034001094	Prokaryotic acetaldehyde dehydrogenase, dimerisation; Region: AcetDehyd-dimer; pfam09290
585034001095	4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated; Region: PRK08195
585034001096	4-hydroxy-2-oxovalerate aldolase, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_HOA; cd07943
585034001097	active site
585034001098	catalytic residues [active]
585034001099	metal binding site [ion binding]; metal-binding site
585034001100	DmpG-like communication domain; Region: DmpG_comm; pfam07836
585034001101	putative 3-hydroxyphenylpropionic transporter MhpT; Provisional; Region: PRK11551
585034001102	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034001103	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034001104	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
585034001105	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
585034001106	S-formylglutathione hydrolase; Region: PLN02442
585034001107	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
585034001108	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
585034001109	substrate binding site [chemical binding]; other site
585034001110	catalytic Zn binding site [ion binding]; other site
585034001111	NAD binding site [chemical binding]; other site
585034001112	structural Zn binding site [ion binding]; other site
585034001113	dimer interface [polypeptide binding]; other site
585034001114	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
585034001115	putative metal binding site [ion binding]; other site
585034001116	putative homodimer interface [polypeptide binding]; other site
585034001117	putative homotetramer interface [polypeptide binding]; other site
585034001118	putative homodimer-homodimer interface [polypeptide binding]; other site
585034001119	putative allosteric switch controlling residues; other site
585034001120	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
585034001121	putative trimer interface [polypeptide binding]; other site
585034001122	putative CoA binding site [chemical binding]; other site
585034001123	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
585034001124	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
585034001125	DXD motif; other site
585034001126	Uncharacterized proteins, LmbE homologs [Function unknown]; Region: COG2120
585034001127	ABC-type taurine transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: TauA; COG4521
585034001128	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585034001129	substrate binding pocket [chemical binding]; other site
585034001130	membrane-bound complex binding site; other site
585034001131	hinge residues; other site
585034001132	taurine transporter ATP-binding subunit; Provisional; Region: tauB; PRK11248
585034001133	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
585034001134	Walker A/P-loop; other site
585034001135	ATP binding site [chemical binding]; other site
585034001136	Q-loop/lid; other site
585034001137	ABC transporter signature motif; other site
585034001138	Walker B; other site
585034001139	D-loop; other site
585034001140	H-loop/switch region; other site
585034001141	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
585034001142	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034001143	dimer interface [polypeptide binding]; other site
585034001144	conserved gate region; other site
585034001145	putative PBP binding loops; other site
585034001146	ABC-ATPase subunit interface; other site
585034001147	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
585034001148	taurine dioxygenase; Reviewed; Region: tauD; PRK09553
585034001149	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
585034001150	dimer interface [polypeptide binding]; other site
585034001151	active site
585034001152	Schiff base residues; other site
585034001153	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
585034001154	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
585034001155	Autotransporter beta-domain; Region: Autotransporter; pfam03797
585034001156	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
585034001157	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
585034001158	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
585034001159	microcin B17 transporter; Reviewed; Region: PRK11098
585034001160	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
585034001161	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
585034001162	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
585034001163	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
585034001164	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
585034001165	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
585034001166	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
585034001167	HTH-like domain; Region: HTH_21; pfam13276
585034001168	Integrase core domain; Region: rve; pfam00665
585034001169	Integrase core domain; Region: rve_3; pfam13683
585034001170	Transposase; Region: HTH_Tnp_1; pfam01527
585034001171	anti-RssB factor; Provisional; Region: PRK10244
585034001172	alkaline phosphatase; Provisional; Region: PRK10518
585034001173	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
585034001174	dimer interface [polypeptide binding]; other site
585034001175	active site
585034001176	hypothetical protein; Provisional; Region: PRK11505
585034001177	psiF repeat; Region: PsiF_repeat; pfam07769
585034001178	psiF repeat; Region: PsiF_repeat; pfam07769
585034001179	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
585034001180	MASE2 domain; Region: MASE2; pfam05230
585034001181	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585034001182	metal binding site [ion binding]; metal-binding site
585034001183	active site
585034001184	I-site; other site
585034001185	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
585034001186	pyrroline-5-carboxylate reductase; Region: PLN02688
585034001187	hypothetical protein; Validated; Region: PRK00124
585034001188	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
585034001189	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
585034001190	ADP binding site [chemical binding]; other site
585034001191	magnesium binding site [ion binding]; other site
585034001192	putative shikimate binding site; other site
585034001193	hypothetical protein; Provisional; Region: PRK10380
585034001194	hypothetical protein; Provisional; Region: PRK10481
585034001195	hypothetical protein; Provisional; Region: PRK10579
585034001196	Protein of unknown function (DUF1861); Region: DUF1861; pfam08950
585034001197	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
585034001198	fructokinase; Reviewed; Region: PRK09557
585034001199	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
585034001200	nucleotide binding site [chemical binding]; other site
585034001201	MFS transport protein AraJ; Provisional; Region: PRK10091
585034001202	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034001203	putative substrate translocation pore; other site
585034001204	exonuclease subunit SbcC; Provisional; Region: PRK10246
585034001205	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585034001206	Walker A/P-loop; other site
585034001207	ATP binding site [chemical binding]; other site
585034001208	Q-loop/lid; other site
585034001209	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585034001210	ABC transporter signature motif; other site
585034001211	Walker B; other site
585034001212	D-loop; other site
585034001213	H-loop/switch region; other site
585034001214	exonuclease subunit SbcD; Provisional; Region: PRK10966
585034001215	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
585034001216	active site
585034001217	metal binding site [ion binding]; metal-binding site
585034001218	DNA binding site [nucleotide binding]
585034001219	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
585034001220	transcriptional regulator PhoB; Provisional; Region: PRK10161
585034001221	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034001222	active site
585034001223	phosphorylation site [posttranslational modification]
585034001224	intermolecular recognition site; other site
585034001225	dimerization interface [polypeptide binding]; other site
585034001226	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585034001227	DNA binding site [nucleotide binding]
585034001228	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
585034001229	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
585034001230	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585034001231	putative active site [active]
585034001232	heme pocket [chemical binding]; other site
585034001233	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585034001234	dimer interface [polypeptide binding]; other site
585034001235	phosphorylation site [posttranslational modification]
585034001236	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034001237	ATP binding site [chemical binding]; other site
585034001238	Mg2+ binding site [ion binding]; other site
585034001239	G-X-G motif; other site
585034001240	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
585034001241	putative proline-specific permease; Provisional; Region: proY; PRK10580
585034001242	Spore germination protein; Region: Spore_permease; cl17796
585034001243	maltodextrin glucosidase; Provisional; Region: PRK10785
585034001244	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
585034001245	homodimer interface [polypeptide binding]; other site
585034001246	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
585034001247	active site
585034001248	homodimer interface [polypeptide binding]; other site
585034001249	catalytic site [active]
585034001250	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
585034001251	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
585034001252	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
585034001253	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
585034001254	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
585034001255	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
585034001256	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
585034001257	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
585034001258	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
585034001259	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
585034001260	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
585034001261	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
585034001262	Protein export membrane protein; Region: SecD_SecF; pfam02355
585034001263	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
585034001264	active site
585034001265	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
585034001266	hypothetical protein; Provisional; Region: PRK11530
585034001267	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
585034001268	ATP cone domain; Region: ATP-cone; pfam03477
585034001269	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
585034001270	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
585034001271	catalytic motif [active]
585034001272	Zn binding site [ion binding]; other site
585034001273	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
585034001274	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
585034001275	homopentamer interface [polypeptide binding]; other site
585034001276	active site
585034001277	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
585034001278	putative RNA binding site [nucleotide binding]; other site
585034001279	thiamine monophosphate kinase; Provisional; Region: PRK05731
585034001280	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
585034001281	ATP binding site [chemical binding]; other site
585034001282	dimerization interface [polypeptide binding]; other site
585034001283	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
585034001284	tetramer interfaces [polypeptide binding]; other site
585034001285	binuclear metal-binding site [ion binding]; other site
585034001286	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
585034001287	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
585034001288	active site
585034001289	catalytic tetrad [active]
585034001290	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
585034001291	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
585034001292	TPP-binding site; other site
585034001293	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
585034001294	PYR/PP interface [polypeptide binding]; other site
585034001295	dimer interface [polypeptide binding]; other site
585034001296	TPP binding site [chemical binding]; other site
585034001297	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
585034001298	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
585034001299	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
585034001300	substrate binding pocket [chemical binding]; other site
585034001301	chain length determination region; other site
585034001302	substrate-Mg2+ binding site; other site
585034001303	catalytic residues [active]
585034001304	aspartate-rich region 1; other site
585034001305	active site lid residues [active]
585034001306	aspartate-rich region 2; other site
585034001307	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
585034001308	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
585034001309	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
585034001310	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
585034001311	Ligand Binding Site [chemical binding]; other site
585034001312	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
585034001313	active site residue [active]
585034001314	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
585034001315	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
585034001316	conserved cys residue [active]
585034001317	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
585034001318	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
585034001319	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
585034001320	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
585034001321	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
585034001322	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034001323	Major Facilitator Superfamily; Region: MFS_1; pfam07690
585034001324	putative substrate translocation pore; other site
585034001325	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
585034001326	Sel1 repeat; Region: Sel1; pfam08238
585034001327	Sel1-like repeats; Region: SEL1; smart00671
585034001328	Sel1-like repeats; Region: SEL1; smart00671
585034001329	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
585034001330	Protein of unknown function (DUF1778); Region: DUF1778; pfam08681
585034001331	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
585034001332	UbiA prenyltransferase family; Region: UbiA; pfam01040
585034001333	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
585034001334	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
585034001335	Subunit I/III interface [polypeptide binding]; other site
585034001336	Subunit III/IV interface [polypeptide binding]; other site
585034001337	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
585034001338	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
585034001339	D-pathway; other site
585034001340	Putative ubiquinol binding site [chemical binding]; other site
585034001341	Low-spin heme (heme b) binding site [chemical binding]; other site
585034001342	Putative water exit pathway; other site
585034001343	Binuclear center (heme o3/CuB) [ion binding]; other site
585034001344	K-pathway; other site
585034001345	Putative proton exit pathway; other site
585034001346	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
585034001347	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
585034001348	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
585034001349	muropeptide transporter; Reviewed; Region: ampG; PRK11902
585034001350	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034001351	putative substrate translocation pore; other site
585034001352	hypothetical protein; Provisional; Region: PRK11627
585034001353	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
585034001354	transcriptional regulator BolA; Provisional; Region: PRK11628
585034001355	trigger factor; Provisional; Region: tig; PRK01490
585034001356	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
585034001357	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
585034001358	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
585034001359	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
585034001360	oligomer interface [polypeptide binding]; other site
585034001361	active site residues [active]
585034001362	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
585034001363	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
585034001364	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034001365	Walker A motif; other site
585034001366	ATP binding site [chemical binding]; other site
585034001367	Walker B motif; other site
585034001368	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
585034001369	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
585034001370	Found in ATP-dependent protease La (LON); Region: LON; smart00464
585034001371	Found in ATP-dependent protease La (LON); Region: LON; smart00464
585034001372	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034001373	Walker A motif; other site
585034001374	ATP binding site [chemical binding]; other site
585034001375	Walker B motif; other site
585034001376	arginine finger; other site
585034001377	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
585034001378	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
585034001379	IHF dimer interface [polypeptide binding]; other site
585034001380	IHF - DNA interface [nucleotide binding]; other site
585034001381	periplasmic folding chaperone; Provisional; Region: PRK10788
585034001382	SurA N-terminal domain; Region: SurA_N_3; cl07813
585034001383	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
585034001384	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
585034001385	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
585034001386	active site
585034001387	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
585034001388	Ligand Binding Site [chemical binding]; other site
585034001389	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
585034001390	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
585034001391	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
585034001392	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
585034001393	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034001394	active site
585034001395	motif I; other site
585034001396	motif II; other site
585034001397	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
585034001398	dimerization interface [polypeptide binding]; other site
585034001399	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
585034001400	putative DNA binding site [nucleotide binding]; other site
585034001401	putative Zn2+ binding site [ion binding]; other site
585034001402	AsnC family; Region: AsnC_trans_reg; pfam01037
585034001403	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
585034001404	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
585034001405	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585034001406	Walker A/P-loop; other site
585034001407	ATP binding site [chemical binding]; other site
585034001408	Q-loop/lid; other site
585034001409	ABC transporter signature motif; other site
585034001410	Walker B; other site
585034001411	D-loop; other site
585034001412	H-loop/switch region; other site
585034001413	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
585034001414	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
585034001415	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
585034001416	Walker A/P-loop; other site
585034001417	ATP binding site [chemical binding]; other site
585034001418	Q-loop/lid; other site
585034001419	ABC transporter signature motif; other site
585034001420	Walker B; other site
585034001421	D-loop; other site
585034001422	H-loop/switch region; other site
585034001423	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
585034001424	Nitrogen regulatory protein P-II; Region: P-II; smart00938
585034001425	ammonium transporter; Provisional; Region: PRK10666
585034001426	acyl-CoA thioesterase II; Provisional; Region: PRK10526
585034001427	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
585034001428	active site
585034001429	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
585034001430	catalytic triad [active]
585034001431	dimer interface [polypeptide binding]; other site
585034001432	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
585034001433	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
585034001434	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
585034001435	DNA binding site [nucleotide binding]
585034001436	active site
585034001437	Uncharacterized conserved protein [Function unknown]; Region: COG5507
585034001438	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
585034001439	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
585034001440	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585034001441	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
585034001442	maltose O-acetyltransferase; Provisional; Region: PRK10092
585034001443	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
585034001444	active site
585034001445	substrate binding site [chemical binding]; other site
585034001446	trimer interface [polypeptide binding]; other site
585034001447	CoA binding site [chemical binding]; other site
585034001448	gene expression modulator; Provisional; Region: PRK10945
585034001449	Biofilm formation regulator YbaJ; Region: YbaJ; pfam10757
585034001450	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
585034001451	Protein export membrane protein; Region: SecD_SecF; cl14618
585034001452	Protein export membrane protein; Region: SecD_SecF; cl14618
585034001453	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
585034001454	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585034001455	HlyD family secretion protein; Region: HlyD_3; pfam13437
585034001456	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
585034001457	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585034001458	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
585034001459	hypothetical protein; Provisional; Region: PRK11281
585034001460	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
585034001461	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
585034001462	Mechanosensitive ion channel; Region: MS_channel; pfam00924
585034001463	hypothetical protein; Provisional; Region: PRK11038
585034001464	primosomal replication protein N''; Provisional; Region: PRK10093
585034001465	hypothetical protein; Provisional; Region: PRK10527
585034001466	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
585034001467	active site
585034001468	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
585034001469	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034001470	Walker A motif; other site
585034001471	ATP binding site [chemical binding]; other site
585034001472	Walker B motif; other site
585034001473	DNA polymerase III subunit delta'; Validated; Region: PRK08485
585034001474	arginine finger; other site
585034001475	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
585034001476	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
585034001477	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
585034001478	hypothetical protein; Validated; Region: PRK00153
585034001479	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecR; COG0353
585034001480	RecR protein; Region: RecR; pfam02132
585034001481	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
585034001482	putative active site [active]
585034001483	putative metal-binding site [ion binding]; other site
585034001484	tetramer interface [polypeptide binding]; other site
585034001485	heat shock protein 90; Provisional; Region: PRK05218
585034001486	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034001487	ATP binding site [chemical binding]; other site
585034001488	Mg2+ binding site [ion binding]; other site
585034001489	G-X-G motif; other site
585034001490	adenylate kinase; Reviewed; Region: adk; PRK00279
585034001491	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
585034001492	AMP-binding site [chemical binding]; other site
585034001493	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
585034001494	ferrochelatase; Region: hemH; TIGR00109
585034001495	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
585034001496	C-terminal domain interface [polypeptide binding]; other site
585034001497	active site
585034001498	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
585034001499	active site
585034001500	N-terminal domain interface [polypeptide binding]; other site
585034001501	acetyl esterase; Provisional; Region: PRK10162
585034001502	inosine/guanosine kinase; Provisional; Region: PRK15074
585034001503	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
585034001504	putative cation:proton antiport protein; Provisional; Region: PRK10669
585034001505	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
585034001506	TrkA-N domain; Region: TrkA_N; pfam02254
585034001507	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034001508	Major Facilitator Superfamily; Region: MFS_1; pfam07690
585034001509	putative substrate translocation pore; other site
585034001510	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
585034001511	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
585034001512	active site
585034001513	metal binding site [ion binding]; metal-binding site
585034001514	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
585034001515	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
585034001516	putative deacylase active site [active]
585034001517	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
585034001518	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
585034001519	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585034001520	non-specific DNA binding site [nucleotide binding]; other site
585034001521	salt bridge; other site
585034001522	sequence-specific DNA binding site [nucleotide binding]; other site
585034001523	copper exporting ATPase; Provisional; Region: copA; PRK10671
585034001524	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
585034001525	metal-binding site [ion binding]
585034001526	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
585034001527	metal-binding site [ion binding]
585034001528	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
585034001529	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034001530	motif II; other site
585034001531	glutaminase; Reviewed; Region: PRK12356
585034001532	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
585034001533	amino acid transporter; Region: 2A0306; TIGR00909
585034001534	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
585034001535	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
585034001536	DNA binding residues [nucleotide binding]
585034001537	dimer interface [polypeptide binding]; other site
585034001538	copper binding site [ion binding]; other site
585034001539	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
585034001540	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
585034001541	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
585034001542	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
585034001543	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585034001544	Walker A/P-loop; other site
585034001545	ATP binding site [chemical binding]; other site
585034001546	Q-loop/lid; other site
585034001547	ABC transporter signature motif; other site
585034001548	Walker B; other site
585034001549	D-loop; other site
585034001550	H-loop/switch region; other site
585034001551	Uncharacterized protein family (UPF0014); Region: UPF0014; pfam03649
585034001552	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
585034001553	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
585034001554	oxidoreductase; Provisional; Region: PRK08017
585034001555	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
585034001556	NADP binding site [chemical binding]; other site
585034001557	active site
585034001558	steroid binding site; other site
585034001559	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
585034001560	active site
585034001561	catalytic triad [active]
585034001562	oxyanion hole [active]
585034001563	switch loop; other site
585034001564	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
585034001565	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
585034001566	Walker A/P-loop; other site
585034001567	ATP binding site [chemical binding]; other site
585034001568	Q-loop/lid; other site
585034001569	ABC transporter signature motif; other site
585034001570	Walker B; other site
585034001571	D-loop; other site
585034001572	H-loop/switch region; other site
585034001573	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
585034001574	FtsX-like permease family; Region: FtsX; pfam02687
585034001575	FtsX-like permease family; Region: FtsX; pfam02687
585034001576	PAAR motif; Region: PAAR_motif; cl15808
585034001577	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
585034001578	RHS Repeat; Region: RHS_repeat; pfam05593
585034001579	RHS Repeat; Region: RHS_repeat; pfam05593
585034001580	RHS Repeat; Region: RHS_repeat; pfam05593
585034001581	RHS Repeat; Region: RHS_repeat; pfam05593
585034001582	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
585034001583	RHS Repeat; Region: RHS_repeat; pfam05593
585034001584	RHS Repeat; Region: RHS_repeat; pfam05593
585034001585	RHS protein; Region: RHS; pfam03527
585034001586	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
585034001587	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
585034001588	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
585034001589	RHS protein; Region: RHS; pfam03527
585034001590	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
585034001591	fragment of conserved hypothetical protein (partial);Evidence 7 : Gene remnant
585034001592	Winged helix-turn helix; Region: HTH_29; pfam13551
585034001593	Helix-turn-helix domain; Region: HTH_28; pfam13518
585034001594	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
585034001595	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
585034001596	active site residue [active]
585034001597	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
585034001598	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034001599	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
585034001600	dimerization interface [polypeptide binding]; other site
585034001601	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
585034001602	ureidoglycolate hydrolase; Provisional; Region: PRK03606
585034001603	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
585034001604	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
585034001605	Bacterial transcriptional regulator; Region: IclR; pfam01614
585034001606	glyoxylate carboligase; Provisional; Region: PRK11269
585034001607	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
585034001608	PYR/PP interface [polypeptide binding]; other site
585034001609	dimer interface [polypeptide binding]; other site
585034001610	TPP binding site [chemical binding]; other site
585034001611	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
585034001612	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
585034001613	TPP-binding site [chemical binding]; other site
585034001614	hydroxypyruvate isomerase; Provisional; Region: PRK09997
585034001615	tartronate semialdehyde reductase; Provisional; Region: PRK15059
585034001616	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
585034001617	nucleobase-cation-symport-1 (NCS1) transporters; solute-binding domain; Region: SLC-NCS1sbd; cd10323
585034001618	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
585034001619	Na binding site [ion binding]; other site
585034001620	substrate binding site [chemical binding]; other site
585034001621	allantoinase; Provisional; Region: PRK08044
585034001622	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
585034001623	active site
585034001624	putative uracil/xanthine transporter; Provisional; Region: PRK11412
585034001625	glycerate kinase II; Provisional; Region: PRK09932
585034001626	Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only]; Region: GlxB; COG3257
585034001627	Protein of unknown function (DUF861); Region: Cupin_3; pfam05899
585034001628	Cupin domain; Region: Cupin_2; cl17218
585034001629	allantoate amidohydrolase; Region: AllC; TIGR03176
585034001630	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
585034001631	active site
585034001632	metal binding site [ion binding]; metal-binding site
585034001633	dimer interface [polypeptide binding]; other site
585034001634	ureidoglycolate dehydrogenase; Provisional; Region: PRK15025
585034001635	membrane protein FdrA; Validated; Region: PRK06091
585034001636	CoA binding domain; Region: CoA_binding; pfam02629
585034001637	CoA-ligase; Region: Ligase_CoA; pfam00549
585034001638	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
585034001639	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
585034001640	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
585034001641	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
585034001642	putative substrate binding site [chemical binding]; other site
585034001643	nucleotide binding site [chemical binding]; other site
585034001644	nucleotide binding site [chemical binding]; other site
585034001645	homodimer interface [polypeptide binding]; other site
585034001646	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
585034001647	ATP-grasp domain; Region: ATP-grasp; pfam02222
585034001648	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
585034001649	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
585034001650	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
585034001651	putative active site [active]
585034001652	putative metal binding site [ion binding]; other site
585034001653	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
585034001654	substrate binding site [chemical binding]; other site
585034001655	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
585034001656	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
585034001657	active site
585034001658	HIGH motif; other site
585034001659	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
585034001660	KMSKS motif; other site
585034001661	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
585034001662	tRNA binding surface [nucleotide binding]; other site
585034001663	anticodon binding site; other site
585034001664	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
585034001665	ribosome-associated protein; Provisional; Region: PRK11507
585034001666	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
585034001667	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
585034001668	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
585034001669	homodimer interface [polypeptide binding]; other site
585034001670	NADP binding site [chemical binding]; other site
585034001671	substrate binding site [chemical binding]; other site
585034001672	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
585034001673	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
585034001674	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585034001675	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
585034001676	outer membrane usher protein FimD; Provisional; Region: PRK15198
585034001677	PapC N-terminal domain; Region: PapC_N; pfam13954
585034001678	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585034001679	PapC C-terminal domain; Region: PapC_C; pfam13953
585034001680	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
585034001681	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
585034001682	transcriptional regulator FimZ; Provisional; Region: PRK09935
585034001683	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034001684	active site
585034001685	phosphorylation site [posttranslational modification]
585034001686	intermolecular recognition site; other site
585034001687	dimerization interface [polypeptide binding]; other site
585034001688	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585034001689	DNA binding residues [nucleotide binding]
585034001690	dimerization interface [polypeptide binding]; other site
585034001691	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
585034001692	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034001693	hypothetical protein; Provisional; Region: PRK09936
585034001694	bacteriophage N4 receptor, outer membrane subunit; Provisional; Region: PRK09782
585034001695	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585034001696	TPR motif; other site
585034001697	binding surface
585034001698	Bacteriophage N adsorption protein A C-term; Region: NfrA_C; pfam13283
585034001699	bacteriophage N4 adsorption protein B; Provisional; Region: nfrB; PRK11234
585034001700	active site
585034001701	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
585034001702	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
585034001703	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
585034001704	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
585034001705	Transposase [DNA replication, recombination, and repair]; Region: COG5433
585034001706	Transposase [DNA replication, recombination, and repair]; Region: COG5433
585034001707	SUKH-3 immunity protein; Region: SUKH-3; pfam14433
585034001708	PAAR motif; Region: PAAR_motif; pfam05488
585034001709	RHS Repeat; Region: RHS_repeat; cl11982
585034001710	RHS Repeat; Region: RHS_repeat; pfam05593
585034001711	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
585034001712	RHS Repeat; Region: RHS_repeat; pfam05593
585034001713	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
585034001714	RHS Repeat; Region: RHS_repeat; pfam05593
585034001715	RHS Repeat; Region: RHS_repeat; cl11982
585034001716	RHS Repeat; Region: RHS_repeat; pfam05593
585034001717	RHS Repeat; Region: RHS_repeat; cl11982
585034001718	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
585034001719	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
585034001720	Uncharacterized conserved protein [Function unknown]; Region: COG5435
585034001721	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
585034001722	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
585034001723	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
585034001724	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
585034001725	sensor kinase CusS; Provisional; Region: PRK09835
585034001726	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585034001727	dimerization interface [polypeptide binding]; other site
585034001728	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585034001729	dimer interface [polypeptide binding]; other site
585034001730	phosphorylation site [posttranslational modification]
585034001731	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034001732	ATP binding site [chemical binding]; other site
585034001733	Mg2+ binding site [ion binding]; other site
585034001734	G-X-G motif; other site
585034001735	DNA-binding transcriptional activator CusR; Provisional; Region: PRK09836
585034001736	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034001737	active site
585034001738	phosphorylation site [posttranslational modification]
585034001739	intermolecular recognition site; other site
585034001740	dimerization interface [polypeptide binding]; other site
585034001741	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585034001742	DNA binding site [nucleotide binding]
585034001743	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
585034001744	periplasmic copper-binding protein; Provisional; Region: PRK09838
585034001745	copper/silver efflux system membrane fusion protein CusB; Provisional; Region: PRK09783
585034001746	HlyD family secretion protein; Region: HlyD_3; pfam13437
585034001747	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
585034001748	phenylalanine transporter; Provisional; Region: PRK10249
585034001749	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
585034001750	Mechanosensitive ion channel; Region: MS_channel; pfam00924
585034001751	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
585034001752	dimer interface [polypeptide binding]; other site
585034001753	FMN binding site [chemical binding]; other site
585034001754	hypothetical protein; Provisional; Region: PRK10250
585034001755	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
585034001756	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
585034001757	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
585034001758	Hok/gef family; Region: HOK_GEF; pfam01848
585034001759	Hok/gef family; Region: HOK_GEF; pfam01848
585034001760	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
585034001761	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
585034001762	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
585034001763	outer membrane receptor FepA; Provisional; Region: PRK13524
585034001764	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585034001765	N-terminal plug; other site
585034001766	ligand-binding site [chemical binding]; other site
585034001767	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
585034001768	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
585034001769	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
585034001770	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
585034001771	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
585034001772	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
585034001773	acyl-activating enzyme (AAE) consensus motif; other site
585034001774	AMP binding site [chemical binding]; other site
585034001775	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
585034001776	LPS O-antigen length regulator; Provisional; Region: PRK10381
585034001777	Chain length determinant protein; Region: Wzz; pfam02706
585034001778	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
585034001779	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
585034001780	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
585034001781	Walker A/P-loop; other site
585034001782	ATP binding site [chemical binding]; other site
585034001783	Q-loop/lid; other site
585034001784	ABC transporter signature motif; other site
585034001785	Walker B; other site
585034001786	D-loop; other site
585034001787	H-loop/switch region; other site
585034001788	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
585034001789	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
585034001790	ABC-ATPase subunit  interface; other site
585034001791	dimer interface [polypeptide binding]; other site
585034001792	putative PBP binding regions; other site
585034001793	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
585034001794	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
585034001795	ABC-ATPase subunit  interface; other site
585034001796	dimer interface [polypeptide binding]; other site
585034001797	putative PBP binding regions; other site
585034001798	enterobactin exporter EntS; Provisional; Region: PRK10489
585034001799	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034001800	putative substrate translocation pore; other site
585034001801	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
585034001802	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
585034001803	siderophore binding site; other site
585034001804	isochorismate synthase EntC; Provisional; Region: PRK15016
585034001805	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
585034001806	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
585034001807	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
585034001808	acyl-activating enzyme (AAE) consensus motif; other site
585034001809	active site
585034001810	AMP binding site [chemical binding]; other site
585034001811	substrate binding site [chemical binding]; other site
585034001812	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
585034001813	hydrophobic substrate binding pocket; other site
585034001814	Isochorismatase family; Region: Isochorismatase; pfam00857
585034001815	active site
585034001816	conserved cis-peptide bond; other site
585034001817	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
585034001818	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
585034001819	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
585034001820	putative NAD(P) binding site [chemical binding]; other site
585034001821	active site
585034001822	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
585034001823	CoenzymeA binding site [chemical binding]; other site
585034001824	subunit interaction site [polypeptide binding]; other site
585034001825	PHB binding site; other site
585034001826	carbon starvation protein A; Provisional; Region: PRK15015
585034001827	Carbon starvation protein CstA; Region: CstA; pfam02554
585034001828	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
585034001829	Uncharacterized small protein [Function unknown]; Region: COG2879
585034001830	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
585034001831	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
585034001832	putative active site [active]
585034001833	metal binding site [ion binding]; metal-binding site
585034001834	methionine aminotransferase; Validated; Region: PRK09082
585034001835	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585034001836	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034001837	homodimer interface [polypeptide binding]; other site
585034001838	catalytic residue [active]
585034001839	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
585034001840	ParB-like nuclease domain; Region: ParBc; pfam02195
585034001841	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
585034001842	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
585034001843	Active Sites [active]
585034001844	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
585034001845	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
585034001846	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034001847	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
585034001848	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
585034001849	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
585034001850	dimerization domain [polypeptide binding]; other site
585034001851	dimer interface [polypeptide binding]; other site
585034001852	catalytic residues [active]
585034001853	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
585034001854	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
585034001855	dimer interface [polypeptide binding]; other site
585034001856	decamer (pentamer of dimers) interface [polypeptide binding]; other site
585034001857	catalytic triad [active]
585034001858	peroxidatic and resolving cysteines [active]
585034001859	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
585034001860	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
585034001861	catalytic residue [active]
585034001862	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
585034001863	catalytic residues [active]
585034001864	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
585034001865	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585034001866	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
585034001867	Ligand Binding Site [chemical binding]; other site
585034001868	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
585034001869	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
585034001870	NAD binding site [chemical binding]; other site
585034001871	catalytic Zn binding site [ion binding]; other site
585034001872	structural Zn binding site [ion binding]; other site
585034001873	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
585034001874	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
585034001875	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
585034001876	B1 nucleotide binding pocket [chemical binding]; other site
585034001877	B2 nucleotide binding pocket [chemical binding]; other site
585034001878	CAS motifs; other site
585034001879	active site
585034001880	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
585034001881	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
585034001882	transmembrane helices; other site
585034001883	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
585034001884	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
585034001885	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
585034001886	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
585034001887	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
585034001888	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
585034001889	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
585034001890	putative active site [active]
585034001891	(T/H)XGH motif; other site
585034001892	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
585034001893	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585034001894	putative active site [active]
585034001895	heme pocket [chemical binding]; other site
585034001896	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034001897	ATP binding site [chemical binding]; other site
585034001898	Mg2+ binding site [ion binding]; other site
585034001899	G-X-G motif; other site
585034001900	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
585034001901	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034001902	active site
585034001903	phosphorylation site [posttranslational modification]
585034001904	intermolecular recognition site; other site
585034001905	dimerization interface [polypeptide binding]; other site
585034001906	Transcriptional regulator; Region: CitT; pfam12431
585034001907	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
585034001908	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
585034001909	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
585034001910	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
585034001911	DNA-binding site [nucleotide binding]; DNA binding site
585034001912	RNA-binding motif; other site
585034001913	chromosome condensation membrane protein; Provisional; Region: PRK14196
585034001914	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
585034001915	Predicted amidohydrolase [General function prediction only]; Region: COG0388
585034001916	active site
585034001917	catalytic triad [active]
585034001918	dimer interface [polypeptide binding]; other site
585034001919	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
585034001920	lipoyl synthase; Provisional; Region: PRK05481
585034001921	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585034001922	FeS/SAM binding site; other site
585034001923	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
585034001924	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034001925	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
585034001926	substrate binding pocket [chemical binding]; other site
585034001927	dimerization interface [polypeptide binding]; other site
585034001928	lipoate-protein ligase B; Provisional; Region: PRK14342
585034001929	hypothetical protein; Provisional; Region: PRK04998
585034001930	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
585034001931	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
585034001932	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
585034001933	rare lipoprotein A; Provisional; Region: PRK10672
585034001934	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
585034001935	Sporulation related domain; Region: SPOR; pfam05036
585034001936	cell wall shape-determining protein; Provisional; Region: PRK10794
585034001937	penicillin-binding protein 2; Provisional; Region: PRK10795
585034001938	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
585034001939	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
585034001940	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
585034001941	ribosome-associated protein; Provisional; Region: PRK11538
585034001942	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
585034001943	catalytic core [active]
585034001944	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
585034001945	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
585034001946	active site
585034001947	(T/H)XGH motif; other site
585034001948	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
585034001949	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
585034001950	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
585034001951	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
585034001952	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
585034001953	HIGH motif; other site
585034001954	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
585034001955	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
585034001956	active site
585034001957	KMSKS motif; other site
585034001958	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
585034001959	tRNA binding surface [nucleotide binding]; other site
585034001960	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
585034001961	hypothetical protein; Provisional; Region: PRK11032
585034001962	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
585034001963	Sel1-like repeats; Region: SEL1; smart00671
585034001964	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
585034001965	Sel1-like repeats; Region: SEL1; smart00671
585034001966	Sel1-like repeats; Region: SEL1; smart00671
585034001967	Sel1-like repeats; Region: SEL1; smart00671
585034001968	Sel1-like repeats; Region: SEL1; smart00671
585034001969	Sel1-like repeats; Region: SEL1; smart00671
585034001970	Sel1-like repeats; Region: SEL1; smart00671
585034001971	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
585034001972	DnaJ domain; Region: DnaJ; pfam00226
585034001973	HSP70 interaction site [polypeptide binding]; other site
585034001974	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
585034001975	Sel1-like repeats; Region: SEL1; smart00671
585034001976	Sel1-like repeats; Region: SEL1; smart00671
585034001977	Sel1-like repeats; Region: SEL1; smart00671
585034001978	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
585034001979	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cl02542
585034001980	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
585034001981	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
585034001982	nucleotide binding site [chemical binding]; other site
585034001983	putative NEF/HSP70 interaction site [polypeptide binding]; other site
585034001984	SBD interface [polypeptide binding]; other site
585034001985	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
585034001986	active site
585034001987	tetramer interface [polypeptide binding]; other site
585034001988	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
585034001989	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
585034001990	Walker A/P-loop; other site
585034001991	ATP binding site [chemical binding]; other site
585034001992	Q-loop/lid; other site
585034001993	ABC transporter signature motif; other site
585034001994	Walker B; other site
585034001995	D-loop; other site
585034001996	H-loop/switch region; other site
585034001997	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
585034001998	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034001999	dimer interface [polypeptide binding]; other site
585034002000	conserved gate region; other site
585034002001	putative PBP binding loops; other site
585034002002	ABC-ATPase subunit interface; other site
585034002003	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
585034002004	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034002005	dimer interface [polypeptide binding]; other site
585034002006	conserved gate region; other site
585034002007	putative PBP binding loops; other site
585034002008	ABC-ATPase subunit interface; other site
585034002009	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
585034002010	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585034002011	substrate binding pocket [chemical binding]; other site
585034002012	membrane-bound complex binding site; other site
585034002013	hinge residues; other site
585034002014	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
585034002015	Uncharacterized conserved protein [Function unknown]; Region: COG3391
585034002016	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
585034002017	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
585034002018	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
585034002019	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
585034002020	putative active site [active]
585034002021	catalytic triad [active]
585034002022	putative dimer interface [polypeptide binding]; other site
585034002023	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
585034002024	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
585034002025	Transporter associated domain; Region: CorC_HlyC; smart01091
585034002026	metal-binding heat shock protein; Provisional; Region: PRK00016
585034002027	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
585034002028	PhoH-like protein; Region: PhoH; pfam02562
585034002029	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
585034002030	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
585034002031	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585034002032	FeS/SAM binding site; other site
585034002033	TRAM domain; Region: TRAM; pfam01938
585034002034	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
585034002035	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
585034002036	similar to hypothetical protein; Evidence 6 : Doubtful CDS
585034002037	asparagine synthetase B; Provisional; Region: asnB; PRK09431
585034002038	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
585034002039	active site
585034002040	dimer interface [polypeptide binding]; other site
585034002041	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
585034002042	Ligand Binding Site [chemical binding]; other site
585034002043	Molecular Tunnel; other site
585034002044	UMP phosphatase; Provisional; Region: PRK10444
585034002045	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034002046	active site
585034002047	motif I; other site
585034002048	motif II; other site
585034002049	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034002050	MarR family; Region: MarR; pfam01047
585034002051	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
585034002052	ROK family; Region: ROK; pfam00480
585034002053	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
585034002054	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
585034002055	active site
585034002056	dimer interface [polypeptide binding]; other site
585034002057	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
585034002058	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
585034002059	active site
585034002060	trimer interface [polypeptide binding]; other site
585034002061	allosteric site; other site
585034002062	active site lid [active]
585034002063	hexamer (dimer of trimers) interface [polypeptide binding]; other site
585034002064	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
585034002065	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
585034002066	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
585034002067	active site turn [active]
585034002068	phosphorylation site [posttranslational modification]
585034002069	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
585034002070	HPr interaction site; other site
585034002071	glycerol kinase (GK) interaction site [polypeptide binding]; other site
585034002072	active site
585034002073	phosphorylation site [posttranslational modification]
585034002074	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
585034002075	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
585034002076	active site
585034002077	HIGH motif; other site
585034002078	nucleotide binding site [chemical binding]; other site
585034002079	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
585034002080	KMSKS motif; other site
585034002081	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
585034002082	outer membrane porin, OprD family; Region: OprD; pfam03573
585034002083	YbfN-like lipoprotein; Region: YbfN; pfam13982
585034002084	ferric uptake regulator; Provisional; Region: fur; PRK09462
585034002085	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
585034002086	metal binding site 2 [ion binding]; metal-binding site
585034002087	putative DNA binding helix; other site
585034002088	metal binding site 1 [ion binding]; metal-binding site
585034002089	dimer interface [polypeptide binding]; other site
585034002090	structural Zn2+ binding site [ion binding]; other site
585034002091	flavodoxin FldA; Validated; Region: PRK09267
585034002092	LexA regulated protein; Provisional; Region: PRK11675
585034002093	acyl-CoA esterase; Provisional; Region: PRK10673
585034002094	PGAP1-like protein; Region: PGAP1; pfam07819
585034002095	replication initiation regulator SeqA; Provisional; Region: PRK11187
585034002096	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
585034002097	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
585034002098	active site
585034002099	substrate binding site [chemical binding]; other site
585034002100	metal binding site [ion binding]; metal-binding site
585034002101	putrescine transporter; Provisional; Region: potE; PRK10655
585034002102	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
585034002103	ornithine decarboxylase; Provisional; Region: PRK13578
585034002104	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
585034002105	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
585034002106	homodimer interface [polypeptide binding]; other site
585034002107	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034002108	catalytic residue [active]
585034002109	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
585034002110	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
585034002111	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034002112	active site
585034002113	phosphorylation site [posttranslational modification]
585034002114	intermolecular recognition site; other site
585034002115	dimerization interface [polypeptide binding]; other site
585034002116	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585034002117	DNA binding site [nucleotide binding]
585034002118	sensor protein KdpD; Provisional; Region: PRK10490
585034002119	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
585034002120	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
585034002121	Ligand Binding Site [chemical binding]; other site
585034002122	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
585034002123	GAF domain; Region: GAF_3; pfam13492
585034002124	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585034002125	dimer interface [polypeptide binding]; other site
585034002126	phosphorylation site [posttranslational modification]
585034002127	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034002128	ATP binding site [chemical binding]; other site
585034002129	Mg2+ binding site [ion binding]; other site
585034002130	G-X-G motif; other site
585034002131	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
585034002132	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
585034002133	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
585034002134	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
585034002135	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
585034002136	PAAR motif; Region: PAAR_motif; cl15808
585034002137	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
585034002138	RHS Repeat; Region: RHS_repeat; pfam05593
585034002139	RHS Repeat; Region: RHS_repeat; pfam05593
585034002140	RHS Repeat; Region: RHS_repeat; cl11982
585034002141	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
585034002142	RHS Repeat; Region: RHS_repeat; pfam05593
585034002143	RHS Repeat; Region: RHS_repeat; pfam05593
585034002144	RHS protein; Region: RHS; pfam03527
585034002145	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
585034002146	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
585034002147	RHS protein; Region: RHS; pfam03527
585034002148	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
585034002149	fragment of putative transposase (partial);Evidence 7 : Gene remnant; Product type ph : phenotype
585034002150	fragment of putative transposase (partial);Evidence 7 : Gene remnant; Product type ph : phenotype
585034002151	hypothetical protein; Provisional; Region: PRK10167
585034002152	Uncharacterized conserved protein [Function unknown]; Region: COG3272
585034002153	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
585034002154	DNA photolyase; Region: DNA_photolyase; pfam00875
585034002155	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
585034002156	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034002157	putative substrate translocation pore; other site
585034002158	POT family; Region: PTR2; pfam00854
585034002159	Uncharacterized conserved protein [Function unknown]; Region: COG0327
585034002160	metal-binding protein; Provisional; Region: PRK10799
585034002161	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
585034002162	sensor histidine kinase inhibitor, KipI family; Region: TIGR00370
585034002163	biotin-dependent carboxylase uncharacterized domain; Region: urea_amlyse_rel; TIGR00724
585034002164	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
585034002165	putative active site [active]
585034002166	endonuclease VIII; Provisional; Region: PRK10445
585034002167	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
585034002168	DNA binding site [nucleotide binding]
585034002169	catalytic residue [active]
585034002170	putative catalytic residues [active]
585034002171	H2TH interface [polypeptide binding]; other site
585034002172	intercalation triad [nucleotide binding]; other site
585034002173	substrate specificity determining residue; other site
585034002174	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
585034002175	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
585034002176	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
585034002177	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
585034002178	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
585034002179	Fimbrial protein; Region: Fimbrial; pfam00419
585034002180	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
585034002181	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585034002182	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
585034002183	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
585034002184	PapC N-terminal domain; Region: PapC_N; pfam13954
585034002185	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585034002186	PapC C-terminal domain; Region: PapC_C; pfam13953
585034002187	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
585034002188	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
585034002189	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
585034002190	dimer interface [polypeptide binding]; other site
585034002191	active site
585034002192	citrylCoA binding site [chemical binding]; other site
585034002193	NADH binding [chemical binding]; other site
585034002194	cationic pore residues; other site
585034002195	oxalacetate/citrate binding site [chemical binding]; other site
585034002196	coenzyme A binding site [chemical binding]; other site
585034002197	catalytic triad [active]
585034002198	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
585034002199	Iron-sulfur protein interface; other site
585034002200	proximal quinone binding site [chemical binding]; other site
585034002201	SdhD (CybS) interface [polypeptide binding]; other site
585034002202	proximal heme binding site [chemical binding]; other site
585034002203	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
585034002204	SdhC subunit interface [polypeptide binding]; other site
585034002205	proximal heme binding site [chemical binding]; other site
585034002206	cardiolipin binding site; other site
585034002207	Iron-sulfur protein interface; other site
585034002208	proximal quinone binding site [chemical binding]; other site
585034002209	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
585034002210	L-aspartate oxidase; Provisional; Region: PRK06175
585034002211	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
585034002212	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
585034002213	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
585034002214	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
585034002215	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
585034002216	TPP-binding site [chemical binding]; other site
585034002217	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
585034002218	dimer interface [polypeptide binding]; other site
585034002219	PYR/PP interface [polypeptide binding]; other site
585034002220	TPP binding site [chemical binding]; other site
585034002221	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
585034002222	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
585034002223	E3 interaction surface; other site
585034002224	lipoyl attachment site [posttranslational modification]; other site
585034002225	e3 binding domain; Region: E3_binding; pfam02817
585034002226	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
585034002227	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
585034002228	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
585034002229	CoA-ligase; Region: Ligase_CoA; pfam00549
585034002230	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
585034002231	CoA binding domain; Region: CoA_binding; smart00881
585034002232	CoA-ligase; Region: Ligase_CoA; pfam00549
585034002233	DNA-binding transcriptional repressor MngR; Provisional; Region: PRK09764
585034002234	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034002235	DNA-binding site [nucleotide binding]; DNA binding site
585034002236	UTRA domain; Region: UTRA; pfam07702
585034002237	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
585034002238	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
585034002239	active site
585034002240	phosphorylation site [posttranslational modification]
585034002241	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
585034002242	active site
585034002243	P-loop; other site
585034002244	phosphorylation site [posttranslational modification]
585034002245	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
585034002246	alpha-mannosidase; Provisional; Region: PRK09819
585034002247	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
585034002248	active site
585034002249	metal binding site [ion binding]; metal-binding site
585034002250	catalytic site [active]
585034002251	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
585034002252	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
585034002253	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
585034002254	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
585034002255	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
585034002256	hypothetical protein; Provisional; Region: PRK10588
585034002257	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
585034002258	active site
585034002259	colicin uptake protein TolQ; Provisional; Region: PRK10801
585034002260	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
585034002261	colicin uptake protein TolR; Provisional; Region: PRK11024
585034002262	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
585034002263	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
585034002264	TolA C-terminal; Region: TolA; pfam06519
585034002265	translocation protein TolB; Provisional; Region: tolB; PRK03629
585034002266	TolB amino-terminal domain; Region: TolB_N; pfam04052
585034002267	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
585034002268	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
585034002269	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
585034002270	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
585034002271	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
585034002272	ligand binding site [chemical binding]; other site
585034002273	tol-pal system protein YbgF; Provisional; Region: PRK10803
585034002274	Tetratricopeptide repeat; Region: TPR_6; pfam13174
585034002275	Tetratricopeptide repeat; Region: TPR_6; pfam13174
585034002276	quinolinate synthetase; Provisional; Region: PRK09375
585034002277	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
585034002278	zinc transporter ZitB; Provisional; Region: PRK03557
585034002279	YbgS-like protein; Region: YbgS; pfam13985
585034002280	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
585034002281	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
585034002282	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
585034002283	catalytic core [active]
585034002284	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
585034002285	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
585034002286	active site
585034002287	catalytic residues [active]
585034002288	galactokinase; Provisional; Region: PRK05101
585034002289	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
585034002290	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
585034002291	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
585034002292	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
585034002293	dimer interface [polypeptide binding]; other site
585034002294	active site
585034002295	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
585034002296	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
585034002297	NAD binding site [chemical binding]; other site
585034002298	homodimer interface [polypeptide binding]; other site
585034002299	active site
585034002300	substrate binding site [chemical binding]; other site
585034002301	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
585034002302	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
585034002303	Walker A/P-loop; other site
585034002304	ATP binding site [chemical binding]; other site
585034002305	Q-loop/lid; other site
585034002306	ABC transporter signature motif; other site
585034002307	Walker B; other site
585034002308	D-loop; other site
585034002309	H-loop/switch region; other site
585034002310	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585034002311	Walker A/P-loop; other site
585034002312	ATP binding site [chemical binding]; other site
585034002313	Q-loop/lid; other site
585034002314	ABC transporter signature motif; other site
585034002315	Walker B; other site
585034002316	D-loop; other site
585034002317	H-loop/switch region; other site
585034002318	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
585034002319	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
585034002320	molybdenum-pterin binding domain; Region: Mop; TIGR00638
585034002321	TOBE domain; Region: TOBE; pfam03459
585034002322	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
585034002323	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
585034002324	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585034002325	substrate binding pocket [chemical binding]; other site
585034002326	membrane-bound complex binding site; other site
585034002327	hinge residues; other site
585034002328	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
585034002329	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034002330	putative PBP binding loops; other site
585034002331	ABC-ATPase subunit interface; other site
585034002332	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
585034002333	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585034002334	Walker A/P-loop; other site
585034002335	ATP binding site [chemical binding]; other site
585034002336	Q-loop/lid; other site
585034002337	ABC transporter signature motif; other site
585034002338	Walker B; other site
585034002339	D-loop; other site
585034002340	H-loop/switch region; other site
585034002341	molybdenum-pterin binding domain; Region: Mop; TIGR00638
585034002342	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
585034002343	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034002344	motif II; other site
585034002345	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034002346	6-phosphogluconolactonase; Provisional; Region: PRK11028
585034002347	Transcriptional regulator [Transcription]; Region: LysR; COG0583
585034002348	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034002349	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
585034002350	putative dimerization interface [polypeptide binding]; other site
585034002351	PrpF protein; Region: PrpF; pfam04303
585034002352	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
585034002353	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
585034002354	transmembrane helices; other site
585034002355	putative hydratase; Provisional; Region: PRK11413
585034002356	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
585034002357	substrate binding site [chemical binding]; other site
585034002358	ligand binding site [chemical binding]; other site
585034002359	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
585034002360	substrate binding site [chemical binding]; other site
585034002361	acyl-CoA thioesterase; Provisional; Region: PRK10531
585034002362	putative pectinesterase; Region: PLN02432; cl01911
585034002363	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
585034002364	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N; cl12235
585034002365	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
585034002366	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
585034002367	dimer interface [polypeptide binding]; other site
585034002368	active site
585034002369	Int/Topo IB signature motif; other site
585034002370	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
585034002371	HTH-like domain; Region: HTH_21; pfam13276
585034002372	Integrase core domain; Region: rve; pfam00665
585034002373	Integrase core domain; Region: rve_3; pfam13683
585034002374	Transposase; Region: HTH_Tnp_1; pfam01527
585034002375	DNA polymerase III, theta subunit; Region: DNA_pol3_theta; cl11635
585034002376	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
585034002377	DksA-like zinc finger domain containing protein; Region: PHA00080
585034002378	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
585034002379	phage recombination protein Bet; Region: bet_lambda; TIGR01913
585034002380	Host-nuclease inhibitor protein Gam; Region: Gam; pfam06064
585034002381	FtsZ inhibitor protein; Reviewed; Region: kil; PRK11354
585034002382	Domain of unknown function (DUF4411); Region: DUF4411; pfam14367
585034002383	Domain of unknown function (DUF955); Region: DUF955; cl01076
585034002384	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585034002385	non-specific DNA binding site [nucleotide binding]; other site
585034002386	Predicted transcriptional regulator [Transcription]; Region: COG2932
585034002387	salt bridge; other site
585034002388	sequence-specific DNA binding site [nucleotide binding]; other site
585034002389	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
585034002390	Catalytic site [active]
585034002391	Uncharacterized protein conserved in bacteria, prophage-related [Function unknown]; Region: COG4197
585034002392	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
585034002393	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
585034002394	Replication protein P; Region: Phage_lambda_P; pfam06992
585034002395	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
585034002396	DNA polymerase III, theta subunit; Region: DNA_pol3_theta; cl11635
585034002397	hypothetical protein; Provisional; Region: PRK09741
585034002398	prophage protein NinE; Provisional; Region: PRK09689
585034002399	Protein of unknown function (DUF1364); Region: DUF1364; pfam07102
585034002400	endodeoxyribonuclease RUS; Reviewed; Region: PRK09786
585034002401	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
585034002402	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
585034002403	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
585034002404	trimer interface [polypeptide binding]; other site
585034002405	eyelet of channel; other site
585034002406	Lysis protein S; Region: Lysis_S; pfam04971
585034002407	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
585034002408	catalytic residues [active]
585034002409	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
585034002410	Bor protein; Region: Lambda_Bor; pfam06291
585034002411	fragment of conserved hypothetical protein; Qin prophage (partial);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585034002412	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
585034002413	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
585034002414	gpW; Region: gpW; pfam02831
585034002415	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
585034002416	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
585034002417	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
585034002418	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
585034002419	tandem repeat interface [polypeptide binding]; other site
585034002420	oligomer interface [polypeptide binding]; other site
585034002421	active site residues [active]
585034002422	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
585034002423	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
585034002424	DNA packaging protein FI; Region: Packaging_FI; pfam14000
585034002425	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
585034002426	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
585034002427	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
585034002428	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
585034002429	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
585034002430	phage minor tail protein G; Region: phage_lambda_G; TIGR01674
585034002431	Minor tail protein T; Region: Phage_tail_T; pfam06223
585034002432	Phage-related minor tail protein [Function unknown]; Region: COG5281
585034002433	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
585034002434	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
585034002435	Phage-related protein [Function unknown]; Region: COG4718
585034002436	Phage-related protein [Function unknown]; Region: gp18; COG4672
585034002437	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
585034002438	MPN+ (JAMM) motif; other site
585034002439	Zinc-binding site [ion binding]; other site
585034002440	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
585034002441	NlpC/P60 family; Region: NLPC_P60; cl17555
585034002442	Phage-related protein, tail component [Function unknown]; Region: COG4723
585034002443	Phage-related protein, tail component [Function unknown]; Region: COG4733
585034002444	Putative phage tail protein; Region: Phage-tail_3; pfam13550
585034002445	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
585034002446	Fibronectin type III protein; Region: DUF3672; pfam12421
585034002447	Enterobacterial Ail/Lom protein; Region: Ail_Lom; pfam06316
585034002448	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
585034002449	Chaperone of endosialidase; Region: Peptidase_S74; pfam13884
585034002450	transcriptional regulator YdeO; Provisional; Region: PRK09940
585034002451	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034002452	Integrase core domain; Region: rve; pfam00665
585034002453	Integrase core domain; Region: rve_3; pfam13683
585034002454	fragment of putative transposase component; CP4-6 prophage (partial);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585034002455	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
585034002456	substrate binding site [chemical binding]; other site
585034002457	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
585034002458	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
585034002459	inhibitor-cofactor binding pocket; inhibition site
585034002460	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034002461	catalytic residue [active]
585034002462	biotin synthase; Provisional; Region: PRK15108
585034002463	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585034002464	FeS/SAM binding site; other site
585034002465	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
585034002466	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
585034002467	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
585034002468	substrate-cofactor binding pocket; other site
585034002469	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034002470	catalytic residue [active]
585034002471	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
585034002472	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034002473	S-adenosylmethionine binding site [chemical binding]; other site
585034002474	AAA domain; Region: AAA_26; pfam13500
585034002475	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
585034002476	Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and...; Region: DTBS; cd03109
585034002477	ADP binding site [chemical binding]; other site
585034002478	excinuclease ABC subunit B; Provisional; Region: PRK05298
585034002479	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585034002480	ATP binding site [chemical binding]; other site
585034002481	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585034002482	nucleotide binding region [chemical binding]; other site
585034002483	ATP-binding site [chemical binding]; other site
585034002484	Ultra-violet resistance protein B; Region: UvrB; pfam12344
585034002485	UvrB/uvrC motif; Region: UVR; pfam02151
585034002486	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
585034002487	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
585034002488	putative substrate binding pocket [chemical binding]; other site
585034002489	dimer interface [polypeptide binding]; other site
585034002490	phosphate binding site [ion binding]; other site
585034002491	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
585034002492	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585034002493	FeS/SAM binding site; other site
585034002494	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
585034002495	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
585034002496	MPT binding site; other site
585034002497	trimer interface [polypeptide binding]; other site
585034002498	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
585034002499	trimer interface [polypeptide binding]; other site
585034002500	dimer interface [polypeptide binding]; other site
585034002501	putative active site [active]
585034002502	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
585034002503	MoaE interaction surface [polypeptide binding]; other site
585034002504	MoeB interaction surface [polypeptide binding]; other site
585034002505	thiocarboxylated glycine; other site
585034002506	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
585034002507	MoaE homodimer interface [polypeptide binding]; other site
585034002508	MoaD interaction [polypeptide binding]; other site
585034002509	active site residues [active]
585034002510	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
585034002511	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
585034002512	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
585034002513	BAX inhibitor (BI)-1/YccA-like protein family; Region: BI-1-like; cl00473
585034002514	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
585034002515	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
585034002516	Predicted integral membrane protein [Function unknown]; Region: COG0392
585034002517	cardiolipin synthase 2; Provisional; Region: PRK11263
585034002518	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
585034002519	putative active site [active]
585034002520	catalytic site [active]
585034002521	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
585034002522	putative active site [active]
585034002523	catalytic site [active]
585034002524	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
585034002525	putative catalytic site [active]
585034002526	putative metal binding site [ion binding]; other site
585034002527	putative phosphate binding site [ion binding]; other site
585034002528	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
585034002529	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
585034002530	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
585034002531	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
585034002532	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
585034002533	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
585034002534	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
585034002535	Walker A/P-loop; other site
585034002536	ATP binding site [chemical binding]; other site
585034002537	Q-loop/lid; other site
585034002538	ABC transporter signature motif; other site
585034002539	Walker B; other site
585034002540	D-loop; other site
585034002541	H-loop/switch region; other site
585034002542	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
585034002543	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
585034002544	Walker A/P-loop; other site
585034002545	ATP binding site [chemical binding]; other site
585034002546	Q-loop/lid; other site
585034002547	ABC transporter signature motif; other site
585034002548	Walker B; other site
585034002549	D-loop; other site
585034002550	H-loop/switch region; other site
585034002551	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
585034002552	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585034002553	HlyD family secretion protein; Region: HlyD_3; pfam13437
585034002554	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
585034002555	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
585034002556	helicase 45; Provisional; Region: PTZ00424
585034002557	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
585034002558	ATP binding site [chemical binding]; other site
585034002559	Mg++ binding site [ion binding]; other site
585034002560	motif III; other site
585034002561	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585034002562	nucleotide binding region [chemical binding]; other site
585034002563	ATP-binding site [chemical binding]; other site
585034002564	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
585034002565	Transposase; Region: DEDD_Tnp_IS110; pfam01548
585034002566	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
585034002567	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3236
585034002568	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
585034002569	DEAD_2; Region: DEAD_2; pfam06733
585034002570	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
585034002571	glycosyl transferase family protein; Provisional; Region: PRK08136
585034002572	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
585034002573	putative dehydrogenase; Provisional; Region: PRK10098
585034002574	hypothetical protein; Provisional; Region: PRK10259
585034002575	hypothetical protein; Provisional; Region: PRK11019
585034002576	Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467
585034002577	catecholate siderophore receptor Fiu; Provisional; Region: PRK09840
585034002578	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585034002579	N-terminal plug; other site
585034002580	ligand-binding site [chemical binding]; other site
585034002581	hypothetical protein; Provisional; Region: PRK10259
585034002582	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
585034002583	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
585034002584	putative mechanosensitive channel protein; Provisional; Region: PRK11465
585034002585	Mechanosensitive ion channel; Region: MS_channel; pfam00924
585034002586	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
585034002587	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
585034002588	Walker A/P-loop; other site
585034002589	ATP binding site [chemical binding]; other site
585034002590	Q-loop/lid; other site
585034002591	ABC transporter signature motif; other site
585034002592	Walker B; other site
585034002593	D-loop; other site
585034002594	H-loop/switch region; other site
585034002595	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
585034002596	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034002597	dimer interface [polypeptide binding]; other site
585034002598	conserved gate region; other site
585034002599	putative PBP binding loops; other site
585034002600	ABC-ATPase subunit interface; other site
585034002601	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
585034002602	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585034002603	substrate binding pocket [chemical binding]; other site
585034002604	membrane-bound complex binding site; other site
585034002605	hinge residues; other site
585034002606	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
585034002607	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
585034002608	dimerization interface [polypeptide binding]; other site
585034002609	DPS ferroxidase diiron center [ion binding]; other site
585034002610	ion pore; other site
585034002611	threonine and homoserine efflux system; Provisional; Region: PRK10532
585034002612	EamA-like transporter family; Region: EamA; pfam00892
585034002613	outer membrane protein X; Provisional; Region: ompX; PRK09408
585034002614	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
585034002615	Sulfatase; Region: Sulfatase; pfam00884
585034002616	manganese transport regulator MntR; Provisional; Region: PRK11050
585034002617	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
585034002618	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
585034002619	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
585034002620	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
585034002621	transmembrane helices; other site
585034002622	L,D-transpeptidase; Provisional; Region: PRK10260
585034002623	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
585034002624	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
585034002625	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585034002626	Walker A/P-loop; other site
585034002627	ATP binding site [chemical binding]; other site
585034002628	Q-loop/lid; other site
585034002629	ABC transporter signature motif; other site
585034002630	Walker B; other site
585034002631	D-loop; other site
585034002632	H-loop/switch region; other site
585034002633	ABC transporter; Region: ABC_tran_2; pfam12848
585034002634	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
585034002635	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
585034002636	Transposase; Region: DEDD_Tnp_IS110; pfam01548
585034002637	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
585034002638	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
585034002639	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
585034002640	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034002641	active site
585034002642	motif I; other site
585034002643	motif II; other site
585034002644	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034002645	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
585034002646	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
585034002647	dimer interface [polypeptide binding]; other site
585034002648	active site
585034002649	glycine loop; other site
585034002650	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
585034002651	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
585034002652	active site
585034002653	intersubunit interactions; other site
585034002654	catalytic residue [active]
585034002655	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
585034002656	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
585034002657	ATP binding site [chemical binding]; other site
585034002658	substrate interface [chemical binding]; other site
585034002659	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
585034002660	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
585034002661	dimer interface [polypeptide binding]; other site
585034002662	putative functional site; other site
585034002663	putative MPT binding site; other site
585034002664	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
585034002665	catalytic nucleophile [active]
585034002666	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
585034002667	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585034002668	Walker A/P-loop; other site
585034002669	ATP binding site [chemical binding]; other site
585034002670	Q-loop/lid; other site
585034002671	ABC transporter signature motif; other site
585034002672	Walker B; other site
585034002673	D-loop; other site
585034002674	H-loop/switch region; other site
585034002675	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
585034002676	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585034002677	Walker A/P-loop; other site
585034002678	ATP binding site [chemical binding]; other site
585034002679	Q-loop/lid; other site
585034002680	ABC transporter signature motif; other site
585034002681	Walker B; other site
585034002682	D-loop; other site
585034002683	H-loop/switch region; other site
585034002684	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
585034002685	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
585034002686	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
585034002687	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
585034002688	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034002689	dimer interface [polypeptide binding]; other site
585034002690	conserved gate region; other site
585034002691	putative PBP binding loops; other site
585034002692	ABC-ATPase subunit interface; other site
585034002693	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
585034002694	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
585034002695	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034002696	dimer interface [polypeptide binding]; other site
585034002697	conserved gate region; other site
585034002698	putative PBP binding loops; other site
585034002699	ABC-ATPase subunit interface; other site
585034002700	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585034002701	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
585034002702	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585034002703	metal binding site [ion binding]; metal-binding site
585034002704	active site
585034002705	I-site; other site
585034002706	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
585034002707	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
585034002708	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585034002709	FeS/SAM binding site; other site
585034002710	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
585034002711	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
585034002712	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
585034002713	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
585034002714	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
585034002715	putative C-terminal domain interface [polypeptide binding]; other site
585034002716	putative GSH binding site (G-site) [chemical binding]; other site
585034002717	putative dimer interface [polypeptide binding]; other site
585034002718	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
585034002719	N-terminal domain interface [polypeptide binding]; other site
585034002720	dimer interface [polypeptide binding]; other site
585034002721	substrate binding pocket (H-site) [chemical binding]; other site
585034002722	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
585034002723	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
585034002724	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
585034002725	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
585034002726	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
585034002727	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585034002728	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
585034002729	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
585034002730	active site
585034002731	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
585034002732	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034002733	putative substrate translocation pore; other site
585034002734	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
585034002735	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034002736	active site
585034002737	motif I; other site
585034002738	motif II; other site
585034002739	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034002740	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
585034002741	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034002742	putative substrate translocation pore; other site
585034002743	Major Facilitator Superfamily; Region: MFS_1; pfam07690
585034002744	transcriptional repressor BetI; Region: betaine_BetI; TIGR03384
585034002745	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585034002746	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
585034002747	putative transporter; Provisional; Region: PRK04972
585034002748	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
585034002749	TrkA-C domain; Region: TrkA_C; pfam02080
585034002750	TrkA-C domain; Region: TrkA_C; pfam02080
585034002751	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
585034002752	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
585034002753	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
585034002754	GSH binding site [chemical binding]; other site
585034002755	catalytic residues [active]
585034002756	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
585034002757	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
585034002758	dimer interface [polypeptide binding]; other site
585034002759	FMN binding site [chemical binding]; other site
585034002760	NADPH bind site [chemical binding]; other site
585034002761	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
585034002762	RimK-like ATP-grasp domain; Region: RimK; pfam08443
585034002763	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
585034002764	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
585034002765	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
585034002766	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
585034002767	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585034002768	Walker A/P-loop; other site
585034002769	ATP binding site [chemical binding]; other site
585034002770	Q-loop/lid; other site
585034002771	ABC transporter signature motif; other site
585034002772	Walker B; other site
585034002773	D-loop; other site
585034002774	H-loop/switch region; other site
585034002775	TOBE domain; Region: TOBE_2; pfam08402
585034002776	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
585034002777	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034002778	dimer interface [polypeptide binding]; other site
585034002779	conserved gate region; other site
585034002780	putative PBP binding loops; other site
585034002781	ABC-ATPase subunit interface; other site
585034002782	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
585034002783	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034002784	dimer interface [polypeptide binding]; other site
585034002785	conserved gate region; other site
585034002786	putative PBP binding loops; other site
585034002787	ABC-ATPase subunit interface; other site
585034002788	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
585034002789	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
585034002790	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034002791	S-adenosylmethionine binding site [chemical binding]; other site
585034002792	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
585034002793	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585034002794	substrate binding pocket [chemical binding]; other site
585034002795	membrane-bound complex binding site; other site
585034002796	hinge residues; other site
585034002797	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034002798	dimer interface [polypeptide binding]; other site
585034002799	conserved gate region; other site
585034002800	putative PBP binding loops; other site
585034002801	ABC-ATPase subunit interface; other site
585034002802	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
585034002803	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034002804	dimer interface [polypeptide binding]; other site
585034002805	conserved gate region; other site
585034002806	putative PBP binding loops; other site
585034002807	ABC-ATPase subunit interface; other site
585034002808	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
585034002809	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585034002810	substrate binding pocket [chemical binding]; other site
585034002811	membrane-bound complex binding site; other site
585034002812	hinge residues; other site
585034002813	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
585034002814	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585034002815	Walker A/P-loop; other site
585034002816	ATP binding site [chemical binding]; other site
585034002817	Q-loop/lid; other site
585034002818	ABC transporter signature motif; other site
585034002819	Walker B; other site
585034002820	D-loop; other site
585034002821	H-loop/switch region; other site
585034002822	putative lipoprotein; Provisional; Region: PRK10533
585034002823	hypothetical protein; Provisional; Region: PRK02877
585034002824	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
585034002825	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
585034002826	amidase catalytic site [active]
585034002827	Zn binding residues [ion binding]; other site
585034002828	substrate binding site [chemical binding]; other site
585034002829	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
585034002830	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
585034002831	NAD(P) binding site [chemical binding]; other site
585034002832	active site
585034002833	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
585034002834	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
585034002835	putative NAD(P) binding site [chemical binding]; other site
585034002836	putative active site [active]
585034002837	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
585034002838	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
585034002839	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
585034002840	tetramer interface [polypeptide binding]; other site
585034002841	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034002842	catalytic residue [active]
585034002843	pyruvate dehydrogenase; Provisional; Region: PRK09124
585034002844	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
585034002845	PYR/PP interface [polypeptide binding]; other site
585034002846	dimer interface [polypeptide binding]; other site
585034002847	tetramer interface [polypeptide binding]; other site
585034002848	TPP binding site [chemical binding]; other site
585034002849	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
585034002850	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
585034002851	TPP-binding site [chemical binding]; other site
585034002852	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
585034002853	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
585034002854	FAD binding pocket [chemical binding]; other site
585034002855	FAD binding motif [chemical binding]; other site
585034002856	phosphate binding motif [ion binding]; other site
585034002857	beta-alpha-beta structure motif; other site
585034002858	NAD binding pocket [chemical binding]; other site
585034002859	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
585034002860	catalytic loop [active]
585034002861	iron binding site [ion binding]; other site
585034002862	hybrid cluster protein; Provisional; Region: PRK05290
585034002863	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
585034002864	ACS interaction site; other site
585034002865	CODH interaction site; other site
585034002866	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
585034002867	hybrid metal cluster; other site
585034002868	Predicted membrane protein [Function unknown]; Region: COG2431
585034002869	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
585034002870	amphipathic channel; other site
585034002871	Asn-Pro-Ala signature motifs; other site
585034002872	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
585034002873	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
585034002874	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
585034002875	putative active site [active]
585034002876	putative metal-binding site [ion binding]; other site
585034002877	Protein of unknown function (DUF535); Region: DUF535; pfam04393
585034002878	macrolide transporter subunit MacA; Provisional; Region: PRK11578
585034002879	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585034002880	HlyD family secretion protein; Region: HlyD_3; pfam13437
585034002881	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
585034002882	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
585034002883	Walker A/P-loop; other site
585034002884	ATP binding site [chemical binding]; other site
585034002885	Q-loop/lid; other site
585034002886	ABC transporter signature motif; other site
585034002887	Walker B; other site
585034002888	D-loop; other site
585034002889	H-loop/switch region; other site
585034002890	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
585034002891	FtsX-like permease family; Region: FtsX; pfam02687
585034002892	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
585034002893	DNA-binding site [nucleotide binding]; DNA binding site
585034002894	RNA-binding motif; other site
585034002895	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
585034002896	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
585034002897	Clp amino terminal domain; Region: Clp_N; pfam02861
585034002898	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034002899	Walker A motif; other site
585034002900	ATP binding site [chemical binding]; other site
585034002901	Walker B motif; other site
585034002902	arginine finger; other site
585034002903	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034002904	Walker A motif; other site
585034002905	ATP binding site [chemical binding]; other site
585034002906	Walker B motif; other site
585034002907	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
585034002908	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
585034002909	rRNA binding site [nucleotide binding]; other site
585034002910	predicted 30S ribosome binding site; other site
585034002911	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
585034002912	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
585034002913	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
585034002914	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
585034002915	Walker A/P-loop; other site
585034002916	ATP binding site [chemical binding]; other site
585034002917	Q-loop/lid; other site
585034002918	ABC transporter signature motif; other site
585034002919	Walker B; other site
585034002920	D-loop; other site
585034002921	H-loop/switch region; other site
585034002922	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
585034002923	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
585034002924	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585034002925	Walker A/P-loop; other site
585034002926	ATP binding site [chemical binding]; other site
585034002927	Q-loop/lid; other site
585034002928	ABC transporter signature motif; other site
585034002929	Walker B; other site
585034002930	D-loop; other site
585034002931	H-loop/switch region; other site
585034002932	thioredoxin reductase; Provisional; Region: PRK10262
585034002933	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
585034002934	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585034002935	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
585034002936	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
585034002937	putative DNA binding site [nucleotide binding]; other site
585034002938	putative Zn2+ binding site [ion binding]; other site
585034002939	AsnC family; Region: AsnC_trans_reg; pfam01037
585034002940	DNA translocase FtsK; Provisional; Region: PRK10263
585034002941	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
585034002942	DNA translocase FtsK; Provisional; Region: PRK10263
585034002943	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
585034002944	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
585034002945	periplasmic chaperone LolA; Region: lolA; TIGR00547
585034002946	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
585034002947	recombination factor protein RarA; Reviewed; Region: PRK13342
585034002948	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034002949	Walker A motif; other site
585034002950	ATP binding site [chemical binding]; other site
585034002951	Walker B motif; other site
585034002952	arginine finger; other site
585034002953	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
585034002954	seryl-tRNA synthetase; Provisional; Region: PRK05431
585034002955	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
585034002956	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
585034002957	dimer interface [polypeptide binding]; other site
585034002958	active site
585034002959	motif 1; other site
585034002960	motif 2; other site
585034002961	motif 3; other site
585034002962	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
585034002963	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
585034002964	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
585034002965	putative [Fe4-S4] binding site [ion binding]; other site
585034002966	putative molybdopterin cofactor binding site [chemical binding]; other site
585034002967	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
585034002968	putative molybdopterin cofactor binding site; other site
585034002969	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
585034002970	4Fe-4S binding domain; Region: Fer4; pfam00037
585034002971	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
585034002972	Isochorismatase family; Region: Isochorismatase; pfam00857
585034002973	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
585034002974	catalytic triad [active]
585034002975	dimer interface [polypeptide binding]; other site
585034002976	conserved cis-peptide bond; other site
585034002977	putative MFS family transporter protein; Provisional; Region: PRK03633
585034002978	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034002979	putative substrate translocation pore; other site
585034002980	Amino acid permease; Region: AA_permease_2; pfam13520
585034002981	Transcriptional regulator [Transcription]; Region: LysR; COG0583
585034002982	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034002983	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
585034002984	putative effector binding pocket; other site
585034002985	putative dimerization interface [polypeptide binding]; other site
585034002986	hypothetical protein; Provisional; Region: PRK09739
585034002987	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
585034002988	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
585034002989	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585034002990	FeS/SAM binding site; other site
585034002991	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
585034002992	Pyruvate formate lyase 1; Region: PFL1; cd01678
585034002993	coenzyme A binding site [chemical binding]; other site
585034002994	active site
585034002995	catalytic residues [active]
585034002996	glycine loop; other site
585034002997	formate transporter; Provisional; Region: PRK10805
585034002998	uncharacterized domain; Region: TIGR00702
585034002999	YcaO-like family; Region: YcaO; pfam02624
585034003000	Predicted membrane protein [Function unknown]; Region: COG2323
585034003001	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
585034003002	homodimer interface [polypeptide binding]; other site
585034003003	substrate-cofactor binding pocket; other site
585034003004	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034003005	catalytic residue [active]
585034003006	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
585034003007	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
585034003008	hinge; other site
585034003009	active site
585034003010	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
585034003011	cytidylate kinase; Provisional; Region: cmk; PRK00023
585034003012	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
585034003013	CMP-binding site; other site
585034003014	The sites determining sugar specificity; other site
585034003015	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
585034003016	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
585034003017	RNA binding site [nucleotide binding]; other site
585034003018	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
585034003019	RNA binding site [nucleotide binding]; other site
585034003020	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
585034003021	RNA binding site [nucleotide binding]; other site
585034003022	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
585034003023	RNA binding site [nucleotide binding]; other site
585034003024	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
585034003025	RNA binding site [nucleotide binding]; other site
585034003026	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
585034003027	IHF dimer interface [polypeptide binding]; other site
585034003028	IHF - DNA interface [nucleotide binding]; other site
585034003029	ComEC family competence protein; Provisional; Region: PRK11539
585034003030	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
585034003031	ComEC/Rec2-related protein; Region: ComEC_N-term; TIGR00360
585034003032	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
585034003033	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
585034003034	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
585034003035	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
585034003036	Walker A/P-loop; other site
585034003037	ATP binding site [chemical binding]; other site
585034003038	Q-loop/lid; other site
585034003039	ABC transporter signature motif; other site
585034003040	Walker B; other site
585034003041	D-loop; other site
585034003042	H-loop/switch region; other site
585034003043	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
585034003044	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
585034003045	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
585034003046	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
585034003047	hypothetical protein; Provisional; Region: PRK11827
585034003048	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
585034003049	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
585034003050	Ligand binding site; other site
585034003051	oligomer interface; other site
585034003052	hypothetical protein; Provisional; Region: PRK10593
585034003053	Uncharacterized conserved protein [Function unknown]; Region: COG1434
585034003054	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
585034003055	putative active site [active]
585034003056	Methyltransferase domain; Region: Methyltransf_31; pfam13847
585034003057	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034003058	S-adenosylmethionine binding site [chemical binding]; other site
585034003059	condesin subunit F; Provisional; Region: PRK05260
585034003060	condesin subunit E; Provisional; Region: PRK05256
585034003061	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
585034003062	MukB N-terminal; Region: MukB; pfam04310
585034003063	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
585034003064	murein L,D-transpeptidase; Provisional; Region: PRK10594
585034003065	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
585034003066	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
585034003067	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
585034003068	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
585034003069	Peptidase M15; Region: Peptidase_M15_3; cl01194
585034003070	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
585034003071	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
585034003072	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585034003073	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034003074	homodimer interface [polypeptide binding]; other site
585034003075	catalytic residue [active]
585034003076	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
585034003077	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
585034003078	trimer interface [polypeptide binding]; other site
585034003079	eyelet of channel; other site
585034003080	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
585034003081	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
585034003082	putative dimer interface [polypeptide binding]; other site
585034003083	putative anticodon binding site; other site
585034003084	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
585034003085	homodimer interface [polypeptide binding]; other site
585034003086	motif 1; other site
585034003087	motif 2; other site
585034003088	active site
585034003089	motif 3; other site
585034003090	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
585034003091	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
585034003092	active site
585034003093	aminopeptidase N; Provisional; Region: pepN; PRK14015
585034003094	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
585034003095	active site
585034003096	Zn binding site [ion binding]; other site
585034003097	aliphatic sulfonates transport ATP-binding subunit; Provisional; Region: ssuB; PRK11247
585034003098	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
585034003099	Walker A/P-loop; other site
585034003100	ATP binding site [chemical binding]; other site
585034003101	Q-loop/lid; other site
585034003102	ABC transporter signature motif; other site
585034003103	Walker B; other site
585034003104	D-loop; other site
585034003105	H-loop/switch region; other site
585034003106	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
585034003107	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034003108	dimer interface [polypeptide binding]; other site
585034003109	conserved gate region; other site
585034003110	putative PBP binding loops; other site
585034003111	ABC-ATPase subunit interface; other site
585034003112	alkanesulfonate monooxygenase; Provisional; Region: PRK00719
585034003113	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
585034003114	active site
585034003115	dimer interface [polypeptide binding]; other site
585034003116	non-prolyl cis peptide bond; other site
585034003117	insertion regions; other site
585034003118	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585034003119	substrate binding pocket [chemical binding]; other site
585034003120	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
585034003121	membrane-bound complex binding site; other site
585034003122	hinge residues; other site
585034003123	NAD(P)H-dependent FMN reductase; Provisional; Region: PRK10569
585034003124	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
585034003125	Fimbrial protein; Region: Fimbrial; cl01416
585034003126	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
585034003127	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585034003128	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
585034003129	outer membrane usher protein; Provisional; Region: PRK15193
585034003130	PapC N-terminal domain; Region: PapC_N; pfam13954
585034003131	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585034003132	PapC C-terminal domain; Region: PapC_C; pfam13953
585034003133	Fimbrial protein; Region: Fimbrial; cl01416
585034003134	Fimbrial protein; Region: Fimbrial; cl01416
585034003135	Fimbrial protein; Region: Fimbrial; cl01416
585034003136	putativi pili assembly chaperone; Provisional; Region: PRK11385
585034003137	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585034003138	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
585034003139	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
585034003140	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
585034003141	quinone interaction residues [chemical binding]; other site
585034003142	active site
585034003143	catalytic residues [active]
585034003144	FMN binding site [chemical binding]; other site
585034003145	substrate binding site [chemical binding]; other site
585034003146	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
585034003147	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
585034003148	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
585034003149	MOSC domain; Region: MOSC; pfam03473
585034003150	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
585034003151	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
585034003152	catalytic loop [active]
585034003153	iron binding site [ion binding]; other site
585034003154	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
585034003155	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
585034003156	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
585034003157	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034003158	S-adenosylmethionine binding site [chemical binding]; other site
585034003159	ABC transporter ATPase component; Reviewed; Region: PRK11147
585034003160	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585034003161	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585034003162	Walker A/P-loop; other site
585034003163	Walker A/P-loop; other site
585034003164	ATP binding site [chemical binding]; other site
585034003165	ATP binding site [chemical binding]; other site
585034003166	Q-loop/lid; other site
585034003167	Q-loop/lid; other site
585034003168	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
585034003169	ABC transporter signature motif; other site
585034003170	Walker B; other site
585034003171	D-loop; other site
585034003172	ABC transporter; Region: ABC_tran_2; pfam12848
585034003173	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
585034003174	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
585034003175	Paraquat-inducible protein A; Region: PqiA; pfam04403
585034003176	Paraquat-inducible protein A; Region: PqiA; pfam04403
585034003177	paraquat-inducible protein B; Provisional; Region: PRK10807
585034003178	mce related protein; Region: MCE; pfam02470
585034003179	mce related protein; Region: MCE; pfam02470
585034003180	mce related protein; Region: MCE; pfam02470
585034003181	DASH complex subunit Duo1; Region: DASH_Duo1; pfam08651
585034003182	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
585034003183	Protein of unknown function (DUF330); Region: DUF330; pfam03886
585034003184	ribosome modulation factor; Provisional; Region: PRK14563
585034003185	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
585034003186	active site 1 [active]
585034003187	dimer interface [polypeptide binding]; other site
585034003188	active site 2 [active]
585034003189	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
585034003190	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
585034003191	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
585034003192	outer membrane protein A; Reviewed; Region: PRK10808
585034003193	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
585034003194	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
585034003195	ligand binding site [chemical binding]; other site
585034003196	cell division inhibitor SulA; Region: sula; TIGR00623
585034003197	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
585034003198	TfoX C-terminal domain; Region: TfoX_C; pfam04994
585034003199	TIGR01666 family membrane protein; Region: YCCS
585034003200	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
585034003201	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
585034003202	Predicted membrane protein [Function unknown]; Region: COG3304
585034003203	Domain of unknown function (DUF307); Region: DUF307; pfam03733
585034003204	Domain of unknown function (DUF307); Region: DUF307; pfam03733
585034003205	DNA helicase IV; Provisional; Region: helD; PRK11054
585034003206	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
585034003207	Part of AAA domain; Region: AAA_19; pfam13245
585034003208	Family description; Region: UvrD_C_2; pfam13538
585034003209	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
585034003210	active site
585034003211	dimer interfaces [polypeptide binding]; other site
585034003212	catalytic residues [active]
585034003213	hypothetical protein; Provisional; Region: PRK03641
585034003214	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
585034003215	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
585034003216	heat shock protein HspQ; Provisional; Region: PRK14129
585034003217	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
585034003218	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
585034003219	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
585034003220	putative RNA binding site [nucleotide binding]; other site
585034003221	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034003222	S-adenosylmethionine binding site [chemical binding]; other site
585034003223	acylphosphatase; Provisional; Region: PRK14439
585034003224	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
585034003225	sulfur transfer protein TusE; Provisional; Region: PRK11508
585034003226	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
585034003227	YccA-like proteins; Region: YccA_like; cd10433
585034003228	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
585034003229	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
585034003230	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
585034003231	hydrogenase 1 large subunit; Provisional; Region: PRK10170
585034003232	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
585034003233	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
585034003234	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
585034003235	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
585034003236	putative substrate-binding site; other site
585034003237	nickel binding site [ion binding]; other site
585034003238	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
585034003239	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
585034003240	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
585034003241	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
585034003242	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
585034003243	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
585034003244	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
585034003245	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
585034003246	catalytic core [active]
585034003247	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
585034003248	cryptic autophosphorylating protein tyrosine kinase Etk; Provisional; Region: PRK09841
585034003249	Chain length determinant protein; Region: Wzz; pfam02706
585034003250	Chain length determinant protein; Region: Wzz; cl15801
585034003251	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
585034003252	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
585034003253	Nucleotide binding site [chemical binding]; other site
585034003254	Low molecular weight phosphatase family; Region: LMWPc; cd00115
585034003255	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
585034003256	active site
585034003257	polysaccharide export protein Wza; Provisional; Region: PRK15078
585034003258	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
585034003259	SLBB domain; Region: SLBB; pfam10531
585034003260	SLBB domain; Region: SLBB; pfam10531
585034003261	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
585034003262	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
585034003263	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
585034003264	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
585034003265	DNA-binding site [nucleotide binding]; DNA binding site
585034003266	RNA-binding motif; other site
585034003267	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
585034003268	DNA-binding site [nucleotide binding]; DNA binding site
585034003269	RNA-binding motif; other site
585034003270	GnsA/GnsB family; Region: GnsAB; pfam08178
585034003271	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
585034003272	4Fe-4S binding domain; Region: Fer4_5; pfam12801
585034003273	4Fe-4S binding domain; Region: Fer4_5; pfam12801
585034003274	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
585034003275	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
585034003276	HAMP domain; Region: HAMP; pfam00672
585034003277	dimerization interface [polypeptide binding]; other site
585034003278	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585034003279	dimer interface [polypeptide binding]; other site
585034003280	phosphorylation site [posttranslational modification]
585034003281	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034003282	ATP binding site [chemical binding]; other site
585034003283	Mg2+ binding site [ion binding]; other site
585034003284	G-X-G motif; other site
585034003285	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034003286	active site
585034003287	phosphorylation site [posttranslational modification]
585034003288	intermolecular recognition site; other site
585034003289	dimerization interface [polypeptide binding]; other site
585034003290	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
585034003291	putative binding surface; other site
585034003292	active site
585034003293	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
585034003294	TorT-like proteins, a periplasmic binding protein family that activates induction of the Tor respiratory system upon trimethylamine N-oxide (TMAO) electron-acceptor binding in bacteria; Region: PBP1_TorT-like; cd06306
585034003295	putative ligand binding site [chemical binding]; other site
585034003296	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
585034003297	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034003298	active site
585034003299	phosphorylation site [posttranslational modification]
585034003300	intermolecular recognition site; other site
585034003301	dimerization interface [polypeptide binding]; other site
585034003302	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585034003303	DNA binding site [nucleotide binding]
585034003304	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
585034003305	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
585034003306	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
585034003307	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
585034003308	molybdopterin cofactor binding site [chemical binding]; other site
585034003309	substrate binding site [chemical binding]; other site
585034003310	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
585034003311	molybdopterin cofactor binding site; other site
585034003312	chaperone protein TorD; Validated; Region: torD; PRK04976
585034003313	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
585034003314	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
585034003315	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
585034003316	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
585034003317	HSP70 interaction site [polypeptide binding]; other site
585034003318	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
585034003319	substrate binding site [polypeptide binding]; other site
585034003320	dimer interface [polypeptide binding]; other site
585034003321	fragment of conserved hypothetical protein (part 1);Evidence 7 : Gene remnant
585034003322	fragment of conserved hypothetical protein (part 2);Evidence 7 : Gene remnant
585034003323	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
585034003324	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
585034003325	catalytic core [active]
585034003326	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
585034003327	hypothetical protein; Provisional; Region: PRK10174
585034003328	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
585034003329	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
585034003330	General stress protein [General function prediction only]; Region: GsiB; COG3729
585034003331	pyrimidine utilization transport protein G; Region: RutG; TIGR03616
585034003332	pyrimidine utilization flavin reductase protein F; Region: RutF; TIGR03615
585034003333	Nitroreductase-like family 5.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_5; cd02148
585034003334	putative FMN binding site [chemical binding]; other site
585034003335	pyrimidine utilization protein D; Region: RutD; TIGR03611
585034003336	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
585034003337	homotrimer interaction site [polypeptide binding]; other site
585034003338	putative active site [active]
585034003339	Isochorismatase family; Region: Isochorismatase; pfam00857
585034003340	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
585034003341	catalytic triad [active]
585034003342	conserved cis-peptide bond; other site
585034003343	pyrimidine utilization protein A; Region: RutA; TIGR03612
585034003344	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
585034003345	active site
585034003346	dimer interface [polypeptide binding]; other site
585034003347	non-prolyl cis peptide bond; other site
585034003348	insertion regions; other site
585034003349	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
585034003350	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
585034003351	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585034003352	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
585034003353	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
585034003354	Predicted transcriptional regulator [Transcription]; Region: COG3905
585034003355	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
585034003356	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
585034003357	Glutamate binding site [chemical binding]; other site
585034003358	NAD binding site [chemical binding]; other site
585034003359	catalytic residues [active]
585034003360	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
585034003361	Na binding site [ion binding]; other site
585034003362	FTR1 family protein; Region: TIGR00145
585034003363	inactive ferrous ion transporter periplasmic protein EfeO; Provisional; Region: PRK10378
585034003364	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
585034003365	Imelysin; Region: Peptidase_M75; pfam09375
585034003366	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
585034003367	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
585034003368	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
585034003369	hypothetical protein; Provisional; Region: PRK10536
585034003370	Protein of unknown function (DUF2726); Region: DUF2726; pfam10881
585034003371	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
585034003372	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
585034003373	putative ligand binding site [chemical binding]; other site
585034003374	NAD binding site [chemical binding]; other site
585034003375	dimerization interface [polypeptide binding]; other site
585034003376	catalytic site [active]
585034003377	putative hydrolase; Validated; Region: PRK09248
585034003378	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
585034003379	active site
585034003380	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
585034003381	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
585034003382	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
585034003383	curli assembly protein CsgF; Provisional; Region: PRK10050
585034003384	curli assembly protein CsgE; Provisional; Region: PRK10386
585034003385	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
585034003386	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585034003387	DNA binding residues [nucleotide binding]
585034003388	dimerization interface [polypeptide binding]; other site
585034003389	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
585034003390	Curlin associated repeat; Region: Curlin_rpt; pfam07012
585034003391	Curlin associated repeat; Region: Curlin_rpt; pfam07012
585034003392	major curlin subunit; Provisional; Region: csgA; PRK10051
585034003393	Curlin associated repeat; Region: Curlin_rpt; pfam07012
585034003394	Curlin associated repeat; Region: Curlin_rpt; pfam07012
585034003395	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
585034003396	Fimbrial protein; Region: Fimbrial; cl01416
585034003397	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
585034003398	putative ADP-ribose binding site [chemical binding]; other site
585034003399	putative active site [active]
585034003400	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
585034003401	PLD-like domain; Region: PLDc_2; pfam13091
585034003402	putative active site [active]
585034003403	catalytic site [active]
585034003404	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
585034003405	PLD-like domain; Region: PLDc_2; pfam13091
585034003406	putative active site [active]
585034003407	catalytic site [active]
585034003408	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
585034003409	Acyltransferase family; Region: Acyl_transf_3; pfam01757
585034003410	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
585034003411	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
585034003412	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
585034003413	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
585034003414	Ligand binding site; other site
585034003415	DXD motif; other site
585034003416	lipoprotein; Provisional; Region: PRK10175
585034003417	secY/secA suppressor protein; Provisional; Region: PRK11467
585034003418	drug efflux system protein MdtG; Provisional; Region: PRK09874
585034003419	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034003420	putative substrate translocation pore; other site
585034003421	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
585034003422	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
585034003423	putative acyl-acceptor binding pocket; other site
585034003424	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
585034003425	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
585034003426	active site residue [active]
585034003427	hypothetical protein; Provisional; Region: PRK03757
585034003428	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
585034003429	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
585034003430	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
585034003431	hydroxyglutarate oxidase; Provisional; Region: PRK11728
585034003432	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
585034003433	DNA damage-inducible protein I; Provisional; Region: PRK10597
585034003434	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
585034003435	active site
585034003436	substrate binding pocket [chemical binding]; other site
585034003437	dimer interface [polypeptide binding]; other site
585034003438	lipoprotein; Provisional; Region: PRK10598
585034003439	glutaredoxin 2; Provisional; Region: PRK10387
585034003440	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
585034003441	C-terminal domain interface [polypeptide binding]; other site
585034003442	GSH binding site (G-site) [chemical binding]; other site
585034003443	catalytic residues [active]
585034003444	putative dimer interface [polypeptide binding]; other site
585034003445	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
585034003446	N-terminal domain interface [polypeptide binding]; other site
585034003447	multidrug resistance protein MdtH; Provisional; Region: PRK11646
585034003448	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034003449	putative substrate translocation pore; other site
585034003450	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
585034003451	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
585034003452	hypothetical protein; Provisional; Region: PRK11239
585034003453	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
585034003454	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
585034003455	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
585034003456	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
585034003457	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
585034003458	MviN-like protein; Region: MVIN; pfam03023
585034003459	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
585034003460	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
585034003461	Flagellar basal body P-ring biosynthesis protein [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FlgA; COG1261
585034003462	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
585034003463	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
585034003464	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
585034003465	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
585034003466	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
585034003467	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
585034003468	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
585034003469	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
585034003470	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
585034003471	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
585034003472	Fragment of flagellar hook protein FlgE (Part 1);Evidence 7 : Gene remnant; PubMedId : 2193164; Product type s : structure
585034003473	fragment of flagellar hook protein (partial);Evidence 7 : Gene remnant; Product type s : structure
585034003474	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
585034003475	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
585034003476	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
585034003477	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
585034003478	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
585034003479	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
585034003480	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
585034003481	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
585034003482	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
585034003483	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
585034003484	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
585034003485	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
585034003486	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
585034003487	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
585034003488	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
585034003489	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
585034003490	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
585034003491	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
585034003492	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
585034003493	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
585034003494	homodimer interface [polypeptide binding]; other site
585034003495	oligonucleotide binding site [chemical binding]; other site
585034003496	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
585034003497	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
585034003498	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
585034003499	RNA binding surface [nucleotide binding]; other site
585034003500	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
585034003501	active site
585034003502	Maf-like protein; Region: Maf; pfam02545
585034003503	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
585034003504	active site
585034003505	dimer interface [polypeptide binding]; other site
585034003506	hypothetical protein; Provisional; Region: PRK11193
585034003507	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
585034003508	putative phosphate acyltransferase; Provisional; Region: PRK05331
585034003509	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
585034003510	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
585034003511	dimer interface [polypeptide binding]; other site
585034003512	active site
585034003513	CoA binding pocket [chemical binding]; other site
585034003514	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
585034003515	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
585034003516	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
585034003517	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
585034003518	NAD(P) binding site [chemical binding]; other site
585034003519	homotetramer interface [polypeptide binding]; other site
585034003520	homodimer interface [polypeptide binding]; other site
585034003521	active site
585034003522	acyl carrier protein; Provisional; Region: acpP; PRK00982
585034003523	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
585034003524	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
585034003525	dimer interface [polypeptide binding]; other site
585034003526	active site
585034003527	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
585034003528	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
585034003529	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034003530	catalytic residue [active]
585034003531	conserved hypothetical protein, YceG family; Region: TIGR00247
585034003532	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
585034003533	dimerization interface [polypeptide binding]; other site
585034003534	thymidylate kinase; Validated; Region: tmk; PRK00698
585034003535	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
585034003536	TMP-binding site; other site
585034003537	ATP-binding site [chemical binding]; other site
585034003538	DNA polymerase III subunit delta'; Validated; Region: PRK07993
585034003539	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
585034003540	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
585034003541	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
585034003542	active site
585034003543	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
585034003544	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
585034003545	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
585034003546	active site turn [active]
585034003547	phosphorylation site [posttranslational modification]
585034003548	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
585034003549	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585034003550	N-terminal plug; other site
585034003551	ligand-binding site [chemical binding]; other site
585034003552	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
585034003553	nucleotide binding site/active site [active]
585034003554	HIT family signature motif; other site
585034003555	catalytic residue [active]
585034003556	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
585034003557	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
585034003558	putative dimer interface [polypeptide binding]; other site
585034003559	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
585034003560	thiamine kinase; Region: ycfN_thiK; TIGR02721
585034003561	active site
585034003562	substrate binding site [chemical binding]; other site
585034003563	ATP binding site [chemical binding]; other site
585034003564	thiamine kinase; Provisional; Region: thiK; PRK10271
585034003565	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
585034003566	beta-hexosaminidase; Provisional; Region: PRK05337
585034003567	hypothetical protein; Provisional; Region: PRK04940
585034003568	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
585034003569	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585034003570	hypothetical protein; Provisional; Region: PRK11280
585034003571	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
585034003572	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585034003573	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
585034003574	L,D-transpeptidase; Provisional; Region: PRK10260
585034003575	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
585034003576	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
585034003577	transcription-repair coupling factor; Provisional; Region: PRK10689
585034003578	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
585034003579	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585034003580	ATP binding site [chemical binding]; other site
585034003581	putative Mg++ binding site [ion binding]; other site
585034003582	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585034003583	nucleotide binding region [chemical binding]; other site
585034003584	ATP-binding site [chemical binding]; other site
585034003585	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
585034003586	Predicted membrane protein [Function unknown]; Region: COG4763
585034003587	Acyltransferase family; Region: Acyl_transf_3; pfam01757
585034003588	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
585034003589	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
585034003590	FtsX-like permease family; Region: FtsX; pfam02687
585034003591	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
585034003592	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
585034003593	Walker A/P-loop; other site
585034003594	ATP binding site [chemical binding]; other site
585034003595	Q-loop/lid; other site
585034003596	ABC transporter signature motif; other site
585034003597	Walker B; other site
585034003598	D-loop; other site
585034003599	H-loop/switch region; other site
585034003600	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
585034003601	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
585034003602	FtsX-like permease family; Region: FtsX; pfam02687
585034003603	fructokinase; Reviewed; Region: PRK09557
585034003604	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
585034003605	nucleotide binding site [chemical binding]; other site
585034003606	NAD-dependent deacetylase; Provisional; Region: PRK00481
585034003607	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
585034003608	NAD+ binding site [chemical binding]; other site
585034003609	substrate binding site [chemical binding]; other site
585034003610	Zn binding site [ion binding]; other site
585034003611	Repair protein; Region: Repair_PSII; cl01535
585034003612	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
585034003613	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
585034003614	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
585034003615	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
585034003616	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034003617	dimer interface [polypeptide binding]; other site
585034003618	conserved gate region; other site
585034003619	putative PBP binding loops; other site
585034003620	ABC-ATPase subunit interface; other site
585034003621	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
585034003622	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034003623	dimer interface [polypeptide binding]; other site
585034003624	conserved gate region; other site
585034003625	putative PBP binding loops; other site
585034003626	ABC-ATPase subunit interface; other site
585034003627	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
585034003628	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585034003629	Walker A/P-loop; other site
585034003630	ATP binding site [chemical binding]; other site
585034003631	Q-loop/lid; other site
585034003632	ABC transporter signature motif; other site
585034003633	Walker B; other site
585034003634	D-loop; other site
585034003635	H-loop/switch region; other site
585034003636	TOBE domain; Region: TOBE_2; pfam08402
585034003637	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
585034003638	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
585034003639	metal binding site [ion binding]; metal-binding site
585034003640	dimer interface [polypeptide binding]; other site
585034003641	Uncharacterized conserved protein [Function unknown]; Region: COG2850
585034003642	Cupin-like domain; Region: Cupin_8; pfam13621
585034003643	sensor protein PhoQ; Provisional; Region: PRK10815
585034003644	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
585034003645	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
585034003646	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
585034003647	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034003648	ATP binding site [chemical binding]; other site
585034003649	Mg2+ binding site [ion binding]; other site
585034003650	G-X-G motif; other site
585034003651	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
585034003652	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034003653	active site
585034003654	phosphorylation site [posttranslational modification]
585034003655	intermolecular recognition site; other site
585034003656	dimerization interface [polypeptide binding]; other site
585034003657	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585034003658	DNA binding site [nucleotide binding]
585034003659	adenylosuccinate lyase; Provisional; Region: PRK09285
585034003660	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
585034003661	tetramer interface [polypeptide binding]; other site
585034003662	active site
585034003663	putative lysogenization regulator; Reviewed; Region: PRK00218
585034003664	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
585034003665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
585034003666	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
585034003667	nudix motif; other site
585034003668	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
585034003669	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
585034003670	probable active site [active]
585034003671	isocitrate dehydrogenase; Validated; Region: PRK07362
585034003672	isocitrate dehydrogenase; Reviewed; Region: PRK07006
585034003673	Protein of unknown function (DUF1398); Region: DUF1398; pfam07166
585034003674	transcriptional regulator MirA; Provisional; Region: PRK15043
585034003675	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
585034003676	DNA binding residues [nucleotide binding]
585034003677	Sensors of blue-light using FAD; Region: BLUF; smart01034
585034003678	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585034003679	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
585034003680	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
585034003681	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
585034003682	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585034003683	heme ABC transporter, heme-binding protein isdE; Region: IsdE; TIGR03659
585034003684	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
585034003685	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
585034003686	Autotransporter beta-domain; Region: Autotransporter; smart00869
585034003687	Autotransporter beta-domain; Region: Autotransporter; smart00869
585034003688	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
585034003689	cell division inhibitor MinD; Provisional; Region: PRK10818
585034003690	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
585034003691	Switch I; other site
585034003692	Switch II; other site
585034003693	septum formation inhibitor; Reviewed; Region: minC; PRK03511
585034003694	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
585034003695	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
585034003696	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
585034003697	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
585034003698	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
585034003699	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
585034003700	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
585034003701	hypothetical protein; Provisional; Region: PRK10691
585034003702	hypothetical protein; Provisional; Region: PRK05170
585034003703	fragment of hemolysin E (part 2);Evidence 7 : Gene remnant; Product type c : carrier
585034003704	fragment of hemolysin E (part 1);Evidence 7 : Gene remnant; Product type c : carrier
585034003705	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
585034003706	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
585034003707	Catalytic site [active]
585034003708	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
585034003709	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
585034003710	active site
585034003711	DNA binding site [nucleotide binding]
585034003712	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
585034003713	disulfide bond formation protein B; Provisional; Region: PRK01749
585034003714	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
585034003715	transmembrane helices; other site
585034003716	fatty acid metabolism regulator; Provisional; Region: PRK04984
585034003717	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034003718	DNA-binding site [nucleotide binding]; DNA binding site
585034003719	FadR C-terminal domain; Region: FadR_C; pfam07840
585034003720	SpoVR family protein; Provisional; Region: PRK11767
585034003721	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
585034003722	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
585034003723	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585034003724	alanine racemase; Reviewed; Region: dadX; PRK03646
585034003725	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
585034003726	active site
585034003727	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
585034003728	substrate binding site [chemical binding]; other site
585034003729	catalytic residues [active]
585034003730	dimer interface [polypeptide binding]; other site
585034003731	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
585034003732	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
585034003733	TrkA-C domain; Region: TrkA_C; pfam02080
585034003734	Transporter associated domain; Region: CorC_HlyC; smart01091
585034003735	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
585034003736	dimer interface [polypeptide binding]; other site
585034003737	catalytic triad [active]
585034003738	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
585034003739	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
585034003740	N-acetyl-D-glucosamine binding site [chemical binding]; other site
585034003741	catalytic residue [active]
585034003742	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
585034003743	Flagellar regulator YcgR; Region: YcgR; pfam07317
585034003744	PilZ domain; Region: PilZ; pfam07238
585034003745	hypothetical protein; Provisional; Region: PRK10457
585034003746	trehalase; Provisional; Region: treA; PRK13271
585034003747	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
585034003748	dihydroxyacetone kinase subunit M; Provisional; Region: PRK11377
585034003749	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3412
585034003750	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
585034003751	dimerization domain swap beta strand [polypeptide binding]; other site
585034003752	regulatory protein interface [polypeptide binding]; other site
585034003753	active site
585034003754	regulatory phosphorylation site [posttranslational modification]; other site
585034003755	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
585034003756	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
585034003757	dihydroxyacetone kinase subunit DhaL; Provisional; Region: PRK10005
585034003758	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK11468
585034003759	Dak1 domain; Region: Dak1; pfam02733
585034003760	DNA-binding transcriptional regulator DhaR; Provisional; Region: PRK11388
585034003761	PAS domain; Region: PAS; smart00091
585034003762	putative active site [active]
585034003763	heme pocket [chemical binding]; other site
585034003764	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034003765	Walker A motif; other site
585034003766	ATP binding site [chemical binding]; other site
585034003767	Walker B motif; other site
585034003768	arginine finger; other site
585034003769	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
585034003770	fragment of putative adhesin; putative autotransporter (part 2);Evidence 7 : Gene remnant; Product type pf : putative factor
585034003771	fragment of putative adhesin; putative autotransporter (part 1);Evidence 7 : Gene remnant; Product type pf : putative factor
585034003772	GTP-binding protein YchF; Reviewed; Region: PRK09601
585034003773	YchF GTPase; Region: YchF; cd01900
585034003774	G1 box; other site
585034003775	GTP/Mg2+ binding site [chemical binding]; other site
585034003776	Switch I region; other site
585034003777	G2 box; other site
585034003778	Switch II region; other site
585034003779	G3 box; other site
585034003780	G4 box; other site
585034003781	G5 box; other site
585034003782	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
585034003783	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
585034003784	putative active site [active]
585034003785	catalytic residue [active]
585034003786	hypothetical protein; Provisional; Region: PRK10692
585034003787	putative transporter; Provisional; Region: PRK11660
585034003788	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
585034003789	Sulfate transporter family; Region: Sulfate_transp; pfam00916
585034003790	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
585034003791	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
585034003792	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
585034003793	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
585034003794	active site
585034003795	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
585034003796	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
585034003797	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
585034003798	outer membrane lipoprotein LolB; Region: lolB; TIGR00548
585034003799	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
585034003800	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
585034003801	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
585034003802	tRNA; other site
585034003803	putative tRNA binding site [nucleotide binding]; other site
585034003804	putative NADP binding site [chemical binding]; other site
585034003805	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
585034003806	peptide chain release factor 1; Validated; Region: prfA; PRK00591
585034003807	This domain is found in peptide chain release factors; Region: PCRF; smart00937
585034003808	RF-1 domain; Region: RF-1; pfam00472
585034003809	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
585034003810	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034003811	hypothetical protein; Provisional; Region: PRK10278
585034003812	hypothetical protein; Provisional; Region: PRK10941
585034003813	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
585034003814	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
585034003815	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
585034003816	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
585034003817	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
585034003818	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
585034003819	cation transport regulator; Reviewed; Region: chaB; PRK09582
585034003820	Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism]; Region: ChaC; COG3703
585034003821	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
585034003822	putative active site pocket [active]
585034003823	dimerization interface [polypeptide binding]; other site
585034003824	putative catalytic residue [active]
585034003825	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
585034003826	putative invasin; Provisional; Region: PRK10177
585034003827	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
585034003828	transcriptional regulator NarL; Provisional; Region: PRK10651
585034003829	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034003830	active site
585034003831	phosphorylation site [posttranslational modification]
585034003832	intermolecular recognition site; other site
585034003833	dimerization interface [polypeptide binding]; other site
585034003834	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585034003835	DNA binding residues [nucleotide binding]
585034003836	dimerization interface [polypeptide binding]; other site
585034003837	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
585034003838	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
585034003839	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585034003840	dimerization interface [polypeptide binding]; other site
585034003841	Histidine kinase; Region: HisKA_3; pfam07730
585034003842	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034003843	ATP binding site [chemical binding]; other site
585034003844	Mg2+ binding site [ion binding]; other site
585034003845	G-X-G motif; other site
585034003846	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
585034003847	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
585034003848	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
585034003849	[4Fe-4S] binding site [ion binding]; other site
585034003850	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
585034003851	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
585034003852	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
585034003853	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
585034003854	molybdopterin cofactor binding site; other site
585034003855	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
585034003856	4Fe-4S binding domain; Region: Fer4; cl02805
585034003857	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
585034003858	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
585034003859	fragment of conserved hypothetical protein (partial);Evidence 7 : Gene remnant
585034003860	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
585034003861	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
585034003862	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
585034003863	putative active site [active]
585034003864	putative substrate binding site [chemical binding]; other site
585034003865	putative cosubstrate binding site; other site
585034003866	catalytic site [active]
585034003867	SEC-C motif; Region: SEC-C; pfam02810
585034003868	hypothetical protein; Provisional; Region: PRK04233
585034003869	hypothetical protein; Provisional; Region: PRK10279
585034003870	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
585034003871	active site
585034003872	nucleophile elbow; other site
585034003873	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034003874	active site
585034003875	response regulator of RpoS; Provisional; Region: PRK10693
585034003876	phosphorylation site [posttranslational modification]
585034003877	intermolecular recognition site; other site
585034003878	dimerization interface [polypeptide binding]; other site
585034003879	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
585034003880	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
585034003881	active site
585034003882	tetramer interface; other site
585034003883	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
585034003884	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
585034003885	thymidine kinase; Provisional; Region: PRK04296
585034003886	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
585034003887	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
585034003888	putative catalytic cysteine [active]
585034003889	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
585034003890	putative active site [active]
585034003891	metal binding site [ion binding]; metal-binding site
585034003892	hypothetical protein; Provisional; Region: PRK11111
585034003893	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
585034003894	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
585034003895	peptide binding site [polypeptide binding]; other site
585034003896	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
585034003897	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034003898	dimer interface [polypeptide binding]; other site
585034003899	conserved gate region; other site
585034003900	putative PBP binding loops; other site
585034003901	ABC-ATPase subunit interface; other site
585034003902	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
585034003903	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
585034003904	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034003905	dimer interface [polypeptide binding]; other site
585034003906	conserved gate region; other site
585034003907	putative PBP binding loops; other site
585034003908	ABC-ATPase subunit interface; other site
585034003909	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
585034003910	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585034003911	Walker A/P-loop; other site
585034003912	ATP binding site [chemical binding]; other site
585034003913	Q-loop/lid; other site
585034003914	ABC transporter signature motif; other site
585034003915	Walker B; other site
585034003916	D-loop; other site
585034003917	H-loop/switch region; other site
585034003918	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
585034003919	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
585034003920	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585034003921	Walker A/P-loop; other site
585034003922	ATP binding site [chemical binding]; other site
585034003923	Q-loop/lid; other site
585034003924	ABC transporter signature motif; other site
585034003925	Walker B; other site
585034003926	D-loop; other site
585034003927	H-loop/switch region; other site
585034003928	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
585034003929	dsDNA-mimic protein; Reviewed; Region: PRK05094
585034003930	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
585034003931	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
585034003932	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
585034003933	putative active site [active]
585034003934	catalytic site [active]
585034003935	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
585034003936	putative active site [active]
585034003937	catalytic site [active]
585034003938	voltage-gated potassium channel; Provisional; Region: PRK10537
585034003939	Ion channel; Region: Ion_trans_2; pfam07885
585034003940	TrkA-N domain; Region: TrkA_N; pfam02254
585034003941	YciI-like protein; Reviewed; Region: PRK11370
585034003942	transport protein TonB; Provisional; Region: PRK10819
585034003943	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
585034003944	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
585034003945	intracellular septation protein A; Reviewed; Region: PRK00259
585034003946	hypothetical protein; Provisional; Region: PRK02868
585034003947	outer membrane protein W; Provisional; Region: PRK10959
585034003948	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3685
585034003949	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
585034003950	dimerization interface [polypeptide binding]; other site
585034003951	metal binding site [ion binding]; metal-binding site
585034003952	General stress protein [General function prediction only]; Region: GsiB; COG3729
585034003953	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
585034003954	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
585034003955	substrate binding site [chemical binding]; other site
585034003956	active site
585034003957	catalytic residues [active]
585034003958	heterodimer interface [polypeptide binding]; other site
585034003959	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
585034003960	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
585034003961	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034003962	catalytic residue [active]
585034003963	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
585034003964	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
585034003965	active site
585034003966	ribulose/triose binding site [chemical binding]; other site
585034003967	phosphate binding site [ion binding]; other site
585034003968	substrate (anthranilate) binding pocket [chemical binding]; other site
585034003969	product (indole) binding pocket [chemical binding]; other site
585034003970	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
585034003971	active site
585034003972	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
585034003973	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
585034003974	glutamine binding [chemical binding]; other site
585034003975	catalytic triad [active]
585034003976	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
585034003977	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
585034003978	anthranilate synthase component I; Provisional; Region: PRK13564
585034003979	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
585034003980	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
585034003981	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
585034003982	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
585034003983	active site
585034003984	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
585034003985	hypothetical protein; Provisional; Region: PRK11630
585034003986	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
585034003987	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
585034003988	RNA binding surface [nucleotide binding]; other site
585034003989	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
585034003990	probable active site [active]
585034003991	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
585034003992	Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557
585034003993	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
585034003994	homodimer interface [polypeptide binding]; other site
585034003995	Walker A motif; other site
585034003996	ATP binding site [chemical binding]; other site
585034003997	hydroxycobalamin binding site [chemical binding]; other site
585034003998	Walker B motif; other site
585034003999	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
585034004000	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
585034004001	NADP binding site [chemical binding]; other site
585034004002	homodimer interface [polypeptide binding]; other site
585034004003	active site
585034004004	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
585034004005	putative inner membrane peptidase; Provisional; Region: PRK11778
585034004006	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
585034004007	tandem repeat interface [polypeptide binding]; other site
585034004008	oligomer interface [polypeptide binding]; other site
585034004009	active site residues [active]
585034004010	hypothetical protein; Provisional; Region: PRK11037
585034004011	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
585034004012	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
585034004013	active site
585034004014	interdomain interaction site; other site
585034004015	putative metal-binding site [ion binding]; other site
585034004016	nucleotide binding site [chemical binding]; other site
585034004017	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
585034004018	domain I; other site
585034004019	DNA binding groove [nucleotide binding]
585034004020	phosphate binding site [ion binding]; other site
585034004021	domain II; other site
585034004022	domain III; other site
585034004023	nucleotide binding site [chemical binding]; other site
585034004024	catalytic site [active]
585034004025	domain IV; other site
585034004026	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
585034004027	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
585034004028	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
585034004029	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
585034004030	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
585034004031	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034004032	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
585034004033	substrate binding site [chemical binding]; other site
585034004034	putative dimerization interface [polypeptide binding]; other site
585034004035	aconitate hydratase; Validated; Region: PRK09277
585034004036	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
585034004037	substrate binding site [chemical binding]; other site
585034004038	ligand binding site [chemical binding]; other site
585034004039	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
585034004040	substrate binding site [chemical binding]; other site
585034004041	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
585034004042	dimerization interface [polypeptide binding]; other site
585034004043	active site
585034004044	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
585034004045	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
585034004046	active site
585034004047	Predicted membrane protein [Function unknown]; Region: COG3771
585034004048	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
585034004049	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
585034004050	TPR motif; other site
585034004051	binding surface
585034004052	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585034004053	binding surface
585034004054	TPR motif; other site
585034004055	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
585034004056	active site
585034004057	dimer interface [polypeptide binding]; other site
585034004058	translation initiation factor Sui1; Validated; Region: PRK06824
585034004059	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
585034004060	putative rRNA binding site [nucleotide binding]; other site
585034004061	lipoprotein; Provisional; Region: PRK10540
585034004062	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
585034004063	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
585034004064	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585034004065	hypothetical protein; Provisional; Region: PRK13658
585034004066	RNase II stability modulator; Provisional; Region: PRK10060
585034004067	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585034004068	putative active site [active]
585034004069	heme pocket [chemical binding]; other site
585034004070	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585034004071	metal binding site [ion binding]; metal-binding site
585034004072	active site
585034004073	I-site; other site
585034004074	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585034004075	exoribonuclease II; Provisional; Region: PRK05054
585034004076	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
585034004077	RNB domain; Region: RNB; pfam00773
585034004078	S1 RNA binding domain; Region: S1; pfam00575
585034004079	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
585034004080	Uncharacterized conserved protein [Function unknown]; Region: COG2128
585034004081	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
585034004082	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
585034004083	NAD binding site [chemical binding]; other site
585034004084	homotetramer interface [polypeptide binding]; other site
585034004085	homodimer interface [polypeptide binding]; other site
585034004086	substrate binding site [chemical binding]; other site
585034004087	active site
585034004088	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
585034004089	putative active site [active]
585034004090	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
585034004091	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585034004092	Walker A/P-loop; other site
585034004093	ATP binding site [chemical binding]; other site
585034004094	Q-loop/lid; other site
585034004095	ABC transporter signature motif; other site
585034004096	Walker B; other site
585034004097	D-loop; other site
585034004098	H-loop/switch region; other site
585034004099	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
585034004100	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585034004101	Walker A/P-loop; other site
585034004102	ATP binding site [chemical binding]; other site
585034004103	Q-loop/lid; other site
585034004104	ABC transporter signature motif; other site
585034004105	Walker B; other site
585034004106	D-loop; other site
585034004107	H-loop/switch region; other site
585034004108	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
585034004109	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
585034004110	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
585034004111	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034004112	dimer interface [polypeptide binding]; other site
585034004113	conserved gate region; other site
585034004114	putative PBP binding loops; other site
585034004115	ABC-ATPase subunit interface; other site
585034004116	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
585034004117	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034004118	dimer interface [polypeptide binding]; other site
585034004119	conserved gate region; other site
585034004120	putative PBP binding loops; other site
585034004121	ABC-ATPase subunit interface; other site
585034004122	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
585034004123	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
585034004124	peptide binding site [polypeptide binding]; other site
585034004125	Protein of unknown function (DUF2543); Region: DUF2543; pfam10820
585034004126	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
585034004127	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
585034004128	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
585034004129	gamma-glutamyl-gamma-aminobutyrate hydrolase; Provisional; Region: puuD; PRK11366
585034004130	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
585034004131	catalytic triad [active]
585034004132	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
585034004133	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585034004134	non-specific DNA binding site [nucleotide binding]; other site
585034004135	salt bridge; other site
585034004136	sequence-specific DNA binding site [nucleotide binding]; other site
585034004137	Cupin domain; Region: Cupin_2; pfam07883
585034004138	gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK09847
585034004139	Escherichia coli NADP+-dependent gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase PuuC-like; Region: ALDH_GABALDH-PuuC; cd07112
585034004140	NAD(P) binding site [chemical binding]; other site
585034004141	catalytic residues [active]
585034004142	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
585034004143	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
585034004144	4-aminobutyrate transaminase; Provisional; Region: PRK09792
585034004145	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
585034004146	inhibitor-cofactor binding pocket; inhibition site
585034004147	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034004148	catalytic residue [active]
585034004149	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
585034004150	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034004151	Walker A motif; other site
585034004152	ATP binding site [chemical binding]; other site
585034004153	Walker B motif; other site
585034004154	arginine finger; other site
585034004155	phage shock protein PspA; Provisional; Region: PRK10698
585034004156	phage shock protein B; Provisional; Region: pspB; PRK09458
585034004157	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
585034004158	phage shock protein C; Region: phageshock_pspC; TIGR02978
585034004159	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
585034004160	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
585034004161	active site residue [active]
585034004162	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
585034004163	sucrose phosphorylase; Provisional; Region: PRK13840
585034004164	active site
585034004165	homodimer interface [polypeptide binding]; other site
585034004166	catalytic site [active]
585034004167	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
585034004168	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
585034004169	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
585034004170	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034004171	dimer interface [polypeptide binding]; other site
585034004172	conserved gate region; other site
585034004173	putative PBP binding loops; other site
585034004174	ABC-ATPase subunit interface; other site
585034004175	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
585034004176	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034004177	dimer interface [polypeptide binding]; other site
585034004178	conserved gate region; other site
585034004179	putative PBP binding loops; other site
585034004180	ABC-ATPase subunit interface; other site
585034004181	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
585034004182	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide and other MDR family members; Region: 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_; cd08255
585034004183	putative NAD(P) binding site [chemical binding]; other site
585034004184	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
585034004185	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
585034004186	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
585034004187	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
585034004188	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
585034004189	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
585034004190	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
585034004191	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
585034004192	beta-phosphoglucomutase; Region: bPGM; TIGR01990
585034004193	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034004194	motif II; other site
585034004195	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
585034004196	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
585034004197	Walker A/P-loop; other site
585034004198	ATP binding site [chemical binding]; other site
585034004199	Q-loop/lid; other site
585034004200	ABC transporter signature motif; other site
585034004201	Walker B; other site
585034004202	D-loop; other site
585034004203	H-loop/switch region; other site
585034004204	TOBE domain; Region: TOBE_2; pfam08402
585034004205	Outer membrane protein G (OmpG); Region: Porin_OmpG; pfam09381
585034004206	Transcriptional regulators [Transcription]; Region: PurR; COG1609
585034004207	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585034004208	DNA binding site [nucleotide binding]
585034004209	domain linker motif; other site
585034004210	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
585034004211	putative dimerization interface [polypeptide binding]; other site
585034004212	putative ligand binding site [chemical binding]; other site
585034004213	Predicted ATPase [General function prediction only]; Region: COG3106
585034004214	Predicted membrane protein [Function unknown]; Region: COG3768
585034004215	TIGR01620 family protein; Region: hyp_HI0043
585034004216	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
585034004217	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
585034004218	putative aromatic amino acid binding site; other site
585034004219	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034004220	Walker A motif; other site
585034004221	ATP binding site [chemical binding]; other site
585034004222	Walker B motif; other site
585034004223	arginine finger; other site
585034004224	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
585034004225	dimer interface [polypeptide binding]; other site
585034004226	catalytic triad [active]
585034004227	peroxidatic and resolving cysteines [active]
585034004228	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
585034004229	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
585034004230	active site
585034004231	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
585034004232	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
585034004233	putative active site [active]
585034004234	Zn binding site [ion binding]; other site
585034004235	atypical (a) SDRs, subgroup 6; Region: SDR_a6; cd05267
585034004236	NADH(P)-binding; Region: NAD_binding_10; pfam13460
585034004237	putative NAD(P) binding site [chemical binding]; other site
585034004238	fragment of putative hydrolase (part 2);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585034004239	fragment of putative hydrolase (part 2);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585034004240	fragment of putative hydrolase (part 1);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585034004241	Transcriptional regulator [Transcription]; Region: LysR; COG0583
585034004242	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034004243	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
585034004244	putative effector binding pocket; other site
585034004245	putative dimerization interface [polypeptide binding]; other site
585034004246	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
585034004247	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
585034004248	peptide binding site [polypeptide binding]; other site
585034004249	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
585034004250	Mechanosensitive ion channel; Region: MS_channel; pfam00924
585034004251	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
585034004252	universal stress protein UspE; Provisional; Region: PRK11175
585034004253	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
585034004254	Ligand Binding Site [chemical binding]; other site
585034004255	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
585034004256	Ligand Binding Site [chemical binding]; other site
585034004257	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
585034004258	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
585034004259	ligand binding site [chemical binding]; other site
585034004260	flexible hinge region; other site
585034004261	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
585034004262	putative switch regulator; other site
585034004263	non-specific DNA interactions [nucleotide binding]; other site
585034004264	DNA binding site [nucleotide binding]
585034004265	sequence specific DNA binding site [nucleotide binding]; other site
585034004266	putative cAMP binding site [chemical binding]; other site
585034004267	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
585034004268	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
585034004269	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
585034004270	DNA binding site [nucleotide binding]
585034004271	active site
585034004272	putative aminobenzoyl-glutamate transporter; Provisional; Region: abgT; PRK11339
585034004273	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
585034004274	amidohydrolase; Region: amidohydrolases; TIGR01891
585034004275	putative metal binding site [ion binding]; other site
585034004276	M20 Peptidases Aminoacyclase-1 indole-3-acetic-L-aspartic acid hydrolase from bacteria and archaea; Region: M20_Acy1_IAAspH_bact; cd05665
585034004277	amidohydrolase; Region: amidohydrolases; TIGR01891
585034004278	putative metal binding site [ion binding]; other site
585034004279	dimer interface [polypeptide binding]; other site
585034004280	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791
585034004281	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034004282	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
585034004283	putative substrate binding pocket [chemical binding]; other site
585034004284	putative dimerization interface [polypeptide binding]; other site
585034004285	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
585034004286	Smr domain; Region: Smr; pfam01713
585034004287	PAS domain S-box; Region: sensory_box; TIGR00229
585034004288	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585034004289	putative active site [active]
585034004290	heme pocket [chemical binding]; other site
585034004291	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
585034004292	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585034004293	metal binding site [ion binding]; metal-binding site
585034004294	active site
585034004295	I-site; other site
585034004296	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
585034004297	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
585034004298	Cl binding site [ion binding]; other site
585034004299	oligomer interface [polypeptide binding]; other site
585034004300	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
585034004301	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
585034004302	ATP binding site [chemical binding]; other site
585034004303	Mg++ binding site [ion binding]; other site
585034004304	motif III; other site
585034004305	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585034004306	nucleotide binding region [chemical binding]; other site
585034004307	ATP-binding site [chemical binding]; other site
585034004308	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
585034004309	putative RNA binding site [nucleotide binding]; other site
585034004310	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
585034004311	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
585034004312	Ligand Binding Site [chemical binding]; other site
585034004313	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
585034004314	Ligand Binding Site [chemical binding]; other site
585034004315	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
585034004316	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
585034004317	trimer interface [polypeptide binding]; other site
585034004318	eyelet of channel; other site
585034004319	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
585034004320	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
585034004321	dimer interface [polypeptide binding]; other site
585034004322	PYR/PP interface [polypeptide binding]; other site
585034004323	TPP binding site [chemical binding]; other site
585034004324	substrate binding site [chemical binding]; other site
585034004325	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
585034004326	Domain of unknown function; Region: EKR; smart00890
585034004327	4Fe-4S binding domain; Region: Fer4_6; pfam12837
585034004328	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
585034004329	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
585034004330	TPP-binding site [chemical binding]; other site
585034004331	dimer interface [polypeptide binding]; other site
585034004332	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
585034004333	Domain of unknown function (DUF333); Region: DUF333; pfam03891
585034004334	heat-inducible protein; Provisional; Region: PRK10449
585034004335	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
585034004336	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
585034004337	putative ligand binding site [chemical binding]; other site
585034004338	putative NAD binding site [chemical binding]; other site
585034004339	catalytic site [active]
585034004340	hypothetical protein; Provisional; Region: PRK10695
585034004341	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
585034004342	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
585034004343	DNA-binding transcriptional activator FeaR; Provisional; Region: PRK09685
585034004344	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034004345	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
585034004346	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
585034004347	NAD(P) binding site [chemical binding]; other site
585034004348	catalytic residues [active]
585034004349	tyramine oxidase; Provisional; Region: tynA; PRK14696
585034004350	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
585034004351	Copper amine oxidase, N2 domain; Region: Cu_amine_oxidN2; pfam02727
585034004352	Copper amine oxidase, N3 domain; Region: Cu_amine_oxidN3; pfam02728
585034004353	Copper amine oxidase, enzyme domain; Region: Cu_amine_oxid; pfam01179
585034004354	bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; Provisional; Region: PRK11563
585034004355	N-terminal domain of the monoamine oxidase C dehydratase; Region: ALDH_MaoC-N; cd07128
585034004356	substrate binding site [chemical binding]; other site
585034004357	dimer interface [polypeptide binding]; other site
585034004358	NADP binding site [chemical binding]; other site
585034004359	catalytic residues [active]
585034004360	MaoC_C  The C-terminal hot dog fold of the MaoC (monoamine oxidase C) dehydratase regulatory protein. Orthologs of MaoC include PaaZ [Escherichia coli] and PaaN [Pseudomonas putida], which are putative ring-opening enzymes involved in phenylacetic acid...; Region: MaoC_C; cd03452
585034004361	substrate binding site [chemical binding]; other site
585034004362	phenylacetate-CoA oxygenase subunit PaaA; Provisional; Region: paaA; PRK13778
585034004363	phenylacetate-CoA oxygenase, PaaG subunit; Region: PA_CoA_Oxy1; TIGR02156
585034004364	phenylacetate-CoA oxygenase subunit PaaB; Provisional; Region: paaB; PRK13781
585034004365	phenylacetate-CoA oxygenase, PaaI subunit; Region: PA_CoA_Oxy3; TIGR02158
585034004366	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
585034004367	phenylacetate-CoA oxygenase, PaaJ subunit; Region: PA_CoA_Oxy4; TIGR02159
585034004368	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
585034004369	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
585034004370	FAD binding pocket [chemical binding]; other site
585034004371	FAD binding motif [chemical binding]; other site
585034004372	phosphate binding motif [ion binding]; other site
585034004373	beta-alpha-beta structure motif; other site
585034004374	NAD(p) ribose binding residues [chemical binding]; other site
585034004375	NAD binding pocket [chemical binding]; other site
585034004376	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
585034004377	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
585034004378	catalytic loop [active]
585034004379	iron binding site [ion binding]; other site
585034004380	enoyl-CoA hydratase-isomerase; Provisional; Region: PRK09674
585034004381	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
585034004382	substrate binding site [chemical binding]; other site
585034004383	oxyanion hole (OAH) forming residues; other site
585034004384	trimer interface [polypeptide binding]; other site
585034004385	enoyl-CoA hydratase; Provisional; Region: PRK08140
585034004386	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
585034004387	substrate binding site [chemical binding]; other site
585034004388	oxyanion hole (OAH) forming residues; other site
585034004389	trimer interface [polypeptide binding]; other site
585034004390	3-hydroxyacyl-CoA dehydrogenase PaaC; Region: PaaC-3OHAcCoADH; TIGR02279
585034004391	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
585034004392	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
585034004393	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
585034004394	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
585034004395	CoenzymeA binding site [chemical binding]; other site
585034004396	subunit interaction site [polypeptide binding]; other site
585034004397	PHB binding site; other site
585034004398	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
585034004399	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
585034004400	dimer interface [polypeptide binding]; other site
585034004401	active site
585034004402	Phenylacetate-CoA ligase (also known as PaaK); Region: PaaK; cd05913
585034004403	phenylacetate-CoA ligase; Region: PA_CoA_ligase; TIGR02155
585034004404	active site
585034004405	AMP binding site [chemical binding]; other site
585034004406	homodimer interface [polypeptide binding]; other site
585034004407	acyl-activating enzyme (AAE) consensus motif; other site
585034004408	CoA binding site [chemical binding]; other site
585034004409	PaaX-like protein; Region: PaaX; pfam07848
585034004410	phenylacetic acid degradation operon negative regulatory protein PaaX; Region: PaaX_trns_reg; TIGR02277
585034004411	PaaX-like protein C-terminal domain; Region: PaaX_C; pfam08223
585034004412	phenylacetic acid degradation protein PaaY; Region: PaaY; TIGR02287
585034004413	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
585034004414	putative trimer interface [polypeptide binding]; other site
585034004415	putative metal binding site [ion binding]; other site
585034004416	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
585034004417	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
585034004418	active site
585034004419	catalytic tetrad [active]
585034004420	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
585034004421	Protein of unknown function (DUF2773); Region: DUF2773; pfam10971
585034004422	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
585034004423	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase [General function prediction only]; Region: COG4589
585034004424	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
585034004425	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
585034004426	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
585034004427	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034004428	S-adenosylmethionine binding site [chemical binding]; other site
585034004429	PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin; Region: PAP2_Aur1_like; cd03386
585034004430	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
585034004431	active site
585034004432	Dual specificity phosphatase, catalytic domain; Region: DSPc; smart00195
585034004433	active site
585034004434	catalytic residues [active]
585034004435	azoreductase; Reviewed; Region: PRK00170
585034004436	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
585034004437	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
585034004438	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585034004439	ATP binding site [chemical binding]; other site
585034004440	putative Mg++ binding site [ion binding]; other site
585034004441	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585034004442	nucleotide binding region [chemical binding]; other site
585034004443	ATP-binding site [chemical binding]; other site
585034004444	Helicase associated domain (HA2); Region: HA2; pfam04408
585034004445	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
585034004446	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
585034004447	Uncharacterized conserved protein [Function unknown]; Region: COG1434
585034004448	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
585034004449	putative active site [active]
585034004450	Escherichia coli lactaldehyde dehydrogenase AldA-like; Region: ALDH_LactADH-AldA; cd07088
585034004451	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
585034004452	NAD binding site [chemical binding]; other site
585034004453	catalytic residues [active]
585034004454	substrate binding site [chemical binding]; other site
585034004455	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
585034004456	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
585034004457	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
585034004458	cytochrome b561; Provisional; Region: PRK11513
585034004459	hypothetical protein; Provisional; Region: PRK10040
585034004460	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
585034004461	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
585034004462	dimer interface [polypeptide binding]; other site
585034004463	ligand binding site [chemical binding]; other site
585034004464	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585034004465	dimerization interface [polypeptide binding]; other site
585034004466	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
585034004467	dimer interface [polypeptide binding]; other site
585034004468	putative CheW interface [polypeptide binding]; other site
585034004469	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
585034004470	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034004471	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
585034004472	dimerization interface [polypeptide binding]; other site
585034004473	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
585034004474	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
585034004475	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
585034004476	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
585034004477	hypothetical protein; Provisional; Region: PRK11415
585034004478	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
585034004479	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585034004480	Coenzyme A binding pocket [chemical binding]; other site
585034004481	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
585034004482	putative trimer interface [polypeptide binding]; other site
585034004483	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
585034004484	putative CoA binding site [chemical binding]; other site
585034004485	putative trimer interface [polypeptide binding]; other site
585034004486	putative CoA binding site [chemical binding]; other site
585034004487	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
585034004488	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
585034004489	gating phenylalanine in ion channel; other site
585034004490	tellurite resistance protein TehB; Provisional; Region: PRK11207
585034004491	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034004492	S-adenosylmethionine binding site [chemical binding]; other site
585034004493	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
585034004494	Transposase IS200 like; Region: Y1_Tnp; cl00848
585034004495	Transposase IS200 like; Region: Y1_Tnp; pfam01797
585034004496	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
585034004497	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
585034004498	Probable transposase; Region: OrfB_IS605; pfam01385
585034004499	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
585034004500	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
585034004501	benzoate transporter; Region: benE; TIGR00843
585034004502	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
585034004503	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585034004504	non-specific DNA binding site [nucleotide binding]; other site
585034004505	salt bridge; other site
585034004506	sequence-specific DNA binding site [nucleotide binding]; other site
585034004507	Cupin domain; Region: Cupin_2; pfam07883
585034004508	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
585034004509	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
585034004510	Peptidase family U32; Region: Peptidase_U32; pfam01136
585034004511	Collagenase; Region: DUF3656; pfam12392
585034004512	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
585034004513	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: COG1598
585034004514	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585034004515	sequence-specific DNA binding site [nucleotide binding]; other site
585034004516	salt bridge; other site
585034004517	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
585034004518	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034004519	DNA-binding site [nucleotide binding]; DNA binding site
585034004520	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585034004521	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034004522	homodimer interface [polypeptide binding]; other site
585034004523	catalytic residue [active]
585034004524	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
585034004525	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
585034004526	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
585034004527	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585034004528	Walker A/P-loop; other site
585034004529	ATP binding site [chemical binding]; other site
585034004530	Q-loop/lid; other site
585034004531	ABC transporter signature motif; other site
585034004532	Walker B; other site
585034004533	D-loop; other site
585034004534	H-loop/switch region; other site
585034004535	TOBE domain; Region: TOBE_2; pfam08402
585034004536	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034004537	dimer interface [polypeptide binding]; other site
585034004538	conserved gate region; other site
585034004539	putative PBP binding loops; other site
585034004540	ABC-ATPase subunit interface; other site
585034004541	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
585034004542	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034004543	ABC-ATPase subunit interface; other site
585034004544	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
585034004545	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
585034004546	tetrameric interface [polypeptide binding]; other site
585034004547	NAD binding site [chemical binding]; other site
585034004548	catalytic residues [active]
585034004549	substrate binding site [chemical binding]; other site
585034004550	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
585034004551	trimer interface [polypeptide binding]; other site
585034004552	active site
585034004553	substrate binding site [chemical binding]; other site
585034004554	CoA binding site [chemical binding]; other site
585034004555	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
585034004556	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
585034004557	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
585034004558	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
585034004559	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
585034004560	Coenzyme A binding pocket [chemical binding]; other site
585034004561	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
585034004562	Prostaglandin dehydrogenases; Region: PGDH; cd05288
585034004563	NAD(P) binding site [chemical binding]; other site
585034004564	substrate binding site [chemical binding]; other site
585034004565	dimer interface [polypeptide binding]; other site
585034004566	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
585034004567	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034004568	DNA-binding site [nucleotide binding]; DNA binding site
585034004569	FCD domain; Region: FCD; pfam07729
585034004570	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
585034004571	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585034004572	N-terminal plug; other site
585034004573	ligand-binding site [chemical binding]; other site
585034004574	PQQ-like domain; Region: PQQ_2; pfam13360
585034004575	L-asparagine permease; Provisional; Region: PRK15049
585034004576	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
585034004577	C-terminal domain interface [polypeptide binding]; other site
585034004578	GSH binding site (G-site) [chemical binding]; other site
585034004579	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
585034004580	dimer interface [polypeptide binding]; other site
585034004581	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
585034004582	dimer interface [polypeptide binding]; other site
585034004583	N-terminal domain interface [polypeptide binding]; other site
585034004584	substrate binding pocket (H-site) [chemical binding]; other site
585034004585	Fragment of conserved hypothetical protein VgrE (Part 1);Evidence 7 : Gene remnant
585034004586	Fragment of conserved hypothetical protein VgrE (Part 2);Evidence 7 : Gene remnant
585034004587	PAAR motif; Region: PAAR_motif; cl15808
585034004588	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
585034004589	RHS Repeat; Region: RHS_repeat; pfam05593
585034004590	RHS Repeat; Region: RHS_repeat; pfam05593
585034004591	RHS Repeat; Region: RHS_repeat; pfam05593
585034004592	RHS Repeat; Region: RHS_repeat; pfam05593
585034004593	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
585034004594	RHS Repeat; Region: RHS_repeat; pfam05593
585034004595	RHS Repeat; Region: RHS_repeat; pfam05593
585034004596	RHS protein; Region: RHS; pfam03527
585034004597	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
585034004598	fragment of putative transposase (partial);Evidence 7 : Gene remnant; Product type ph : phenotype
585034004599	Protein of unknown function (DUF3969); Region: DUF3969; pfam13108
585034004600	PAAR motif; Region: PAAR_motif; cl15808
585034004601	RHS Repeat; Region: RHS_repeat; pfam05593
585034004602	RHS Repeat; Region: RHS_repeat; pfam05593
585034004603	RHS Repeat; Region: RHS_repeat; pfam05593
585034004604	RHS Repeat; Region: RHS_repeat; cl11982
585034004605	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
585034004606	RHS Repeat; Region: RHS_repeat; pfam05593
585034004607	RHS Repeat; Region: RHS_repeat; cl11982
585034004608	RHS Repeat; Region: RHS_repeat; pfam05593
585034004609	RHS Repeat; Region: RHS_repeat; cl11982
585034004610	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
585034004611	RHS protein; Region: RHS; pfam03527
585034004612	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
585034004613	fragment of putative transposase (partial);Evidence 7 : Gene remnant; Product type ph : phenotype
585034004614	4-oxalocrotonate tautomerase; Provisional; Region: PRK01271
585034004615	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
585034004616	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
585034004617	hypothetical protein; Provisional; Region: PRK10281
585034004618	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
585034004619	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
585034004620	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
585034004621	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
585034004622	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
585034004623	[4Fe-4S] binding site [ion binding]; other site
585034004624	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
585034004625	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
585034004626	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
585034004627	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
585034004628	molybdopterin cofactor binding site; other site
585034004629	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
585034004630	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
585034004631	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
585034004632	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
585034004633	aromatic amino acid exporter; Provisional; Region: PRK11689
585034004634	formate dehydrogenase, alpha subunit, proteobacterial-type; Region: formate-DH-alph; TIGR01553
585034004635	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
585034004636	[4Fe-4S] binding site [ion binding]; other site
585034004637	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
585034004638	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
585034004639	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
585034004640	molybdopterin cofactor binding site; other site
585034004641	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
585034004642	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
585034004643	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
585034004644	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
585034004645	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
585034004646	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585034004647	non-specific DNA binding site [nucleotide binding]; other site
585034004648	salt bridge; other site
585034004649	sequence-specific DNA binding site [nucleotide binding]; other site
585034004650	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
585034004651	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
585034004652	NAD binding site [chemical binding]; other site
585034004653	substrate binding site [chemical binding]; other site
585034004654	catalytic Zn binding site [ion binding]; other site
585034004655	tetramer interface [polypeptide binding]; other site
585034004656	structural Zn binding site [ion binding]; other site
585034004657	malate dehydrogenase; Provisional; Region: PRK13529
585034004658	Malic enzyme, N-terminal domain; Region: malic; pfam00390
585034004659	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
585034004660	NAD(P) binding site [chemical binding]; other site
585034004661	Putative biofilm-dependent modulation protein; Region: BDM; cl11581
585034004662	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
585034004663	3-hydroxybutyrate dehydrogenase; Provisional; Region: PRK12429
585034004664	d-3-hydroxybutyrate dehydrogenase (HBDH), classical (c) SDRs; Region: HBDH_SDR_c; cd08940
585034004665	NAD binding site [chemical binding]; other site
585034004666	homotetramer interface [polypeptide binding]; other site
585034004667	homodimer interface [polypeptide binding]; other site
585034004668	substrate binding site [chemical binding]; other site
585034004669	active site
585034004670	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
585034004671	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
585034004672	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
585034004673	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
585034004674	putative acyltransferase; Provisional; Region: PRK05790
585034004675	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
585034004676	dimer interface [polypeptide binding]; other site
585034004677	active site
585034004678	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
585034004679	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
585034004680	Transcriptional regulator [Transcription]; Region: LysR; COG0583
585034004681	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034004682	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
585034004683	putative dimerization interface [polypeptide binding]; other site
585034004684	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
585034004685	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585034004686	Walker A/P-loop; other site
585034004687	ATP binding site [chemical binding]; other site
585034004688	Q-loop/lid; other site
585034004689	ABC transporter signature motif; other site
585034004690	Walker B; other site
585034004691	D-loop; other site
585034004692	H-loop/switch region; other site
585034004693	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
585034004694	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
585034004695	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585034004696	Walker A/P-loop; other site
585034004697	ATP binding site [chemical binding]; other site
585034004698	Q-loop/lid; other site
585034004699	ABC transporter signature motif; other site
585034004700	Walker B; other site
585034004701	D-loop; other site
585034004702	H-loop/switch region; other site
585034004703	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
585034004704	D-ala-D-ala transporter subunit; Provisional; Region: PRK09881
585034004705	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
585034004706	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034004707	dimer interface [polypeptide binding]; other site
585034004708	conserved gate region; other site
585034004709	putative PBP binding loops; other site
585034004710	ABC-ATPase subunit interface; other site
585034004711	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
585034004712	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034004713	dimer interface [polypeptide binding]; other site
585034004714	conserved gate region; other site
585034004715	putative PBP binding loops; other site
585034004716	ABC-ATPase subunit interface; other site
585034004717	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
585034004718	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
585034004719	D-alanyl-D-alanine dipeptidase; Provisional; Region: PRK10178
585034004720	cyclic-di-GMP phosphodiesterase; Provisional; Region: PRK11359
585034004721	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585034004722	putative active site [active]
585034004723	heme pocket [chemical binding]; other site
585034004724	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585034004725	putative active site [active]
585034004726	heme pocket [chemical binding]; other site
585034004727	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585034004728	metal binding site [ion binding]; metal-binding site
585034004729	active site
585034004730	I-site; other site
585034004731	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585034004732	Globin domain present in Globin-Coupled-Sensors (GCS). These domains detect changes in intracellular concentrations of oxygen, carbon monoxyde, or nitrous oxide,  which result in aerotaxis and/or gene regulation. One subgroup, the HemATs, are aerotactic...; Region: sensor_globin; cd01068
585034004733	heme-binding site [chemical binding]; other site
585034004734	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
585034004735	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585034004736	metal binding site [ion binding]; metal-binding site
585034004737	active site
585034004738	I-site; other site
585034004739	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
585034004740	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
585034004741	glutamate:gamma-aminobutyrate antiporter; Region: 2A0307_GadC; TIGR00910
585034004742	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
585034004743	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034004744	catalytic residue [active]
585034004745	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
585034004746	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
585034004747	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
585034004748	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
585034004749	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
585034004750	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
585034004751	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
585034004752	ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178
585034004753	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
585034004754	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
585034004755	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
585034004756	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585034004757	FeS/SAM binding site; other site
585034004758	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
585034004759	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
585034004760	Sulfatase; Region: Sulfatase; pfam00884
585034004761	transcriptional regulator YdeO; Provisional; Region: PRK09940
585034004762	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034004763	putative oxidoreductase; Provisional; Region: PRK09939
585034004764	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
585034004765	putative molybdopterin cofactor binding site [chemical binding]; other site
585034004766	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
585034004767	putative molybdopterin cofactor binding site; other site
585034004768	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
585034004769	mannosyl binding site [chemical binding]; other site
585034004770	Fimbrial protein; Region: Fimbrial; pfam00419
585034004771	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
585034004772	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
585034004773	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
585034004774	PapC N-terminal domain; Region: PapC_N; pfam13954
585034004775	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585034004776	PapC C-terminal domain; Region: PapC_C; pfam13953
585034004777	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
585034004778	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585034004779	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
585034004780	Fimbrial protein; Region: Fimbrial; cl01416
585034004781	Helix-turn-helix domain; Region: HTH_18; pfam12833
585034004782	HipA N-terminal domain; Region: Couple_hipA; pfam13657
585034004783	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
585034004784	HipA-like N-terminal domain; Region: HipA_N; pfam07805
585034004785	HipA-like C-terminal domain; Region: HipA_C; pfam07804
585034004786	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
585034004787	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585034004788	non-specific DNA binding site [nucleotide binding]; other site
585034004789	salt bridge; other site
585034004790	sequence-specific DNA binding site [nucleotide binding]; other site
585034004791	putative lipoprotein/autotransporter domain-containing protein; Provisional; Region: PRK14849
585034004792	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
585034004793	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
585034004794	Autotransporter beta-domain; Region: Autotransporter; pfam03797
585034004795	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
585034004796	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
585034004797	putative N- and C-terminal domain interface [polypeptide binding]; other site
585034004798	putative active site [active]
585034004799	putative MgATP binding site [chemical binding]; other site
585034004800	catalytic site [active]
585034004801	metal binding site [ion binding]; metal-binding site
585034004802	putative carbohydrate binding site [chemical binding]; other site
585034004803	transcriptional regulator LsrR; Provisional; Region: PRK15418
585034004804	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
585034004805	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
585034004806	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
585034004807	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
585034004808	Walker A/P-loop; other site
585034004809	ATP binding site [chemical binding]; other site
585034004810	Q-loop/lid; other site
585034004811	ABC transporter signature motif; other site
585034004812	Walker B; other site
585034004813	D-loop; other site
585034004814	H-loop/switch region; other site
585034004815	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
585034004816	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585034004817	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585034004818	TM-ABC transporter signature motif; other site
585034004819	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585034004820	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585034004821	TM-ABC transporter signature motif; other site
585034004822	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
585034004823	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
585034004824	ligand binding site [chemical binding]; other site
585034004825	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
585034004826	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
585034004827	putative active site; other site
585034004828	catalytic residue [active]
585034004829	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
585034004830	Trans-aconitate methyltransferase [General function prediction only]; Region: Tam; COG4106
585034004831	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034004832	S-adenosylmethionine binding site [chemical binding]; other site
585034004833	Predicted membrane protein [Function unknown]; Region: COG3781
585034004834	altronate oxidoreductase; Provisional; Region: PRK03643
585034004835	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
585034004836	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
585034004837	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
585034004838	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585034004839	metal binding site [ion binding]; metal-binding site
585034004840	active site
585034004841	I-site; other site
585034004842	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
585034004843	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
585034004844	glutaminase; Provisional; Region: PRK00971
585034004845	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
585034004846	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
585034004847	NAD(P) binding site [chemical binding]; other site
585034004848	catalytic residues [active]
585034004849	Transcriptional regulator [Transcription]; Region: LysR; COG0583
585034004850	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034004851	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
585034004852	putative dimerization interface [polypeptide binding]; other site
585034004853	fragment of conserved hypothetical protein (part 1);Evidence 7 : Gene remnant
585034004854	fragment of conserved hypothetical protein (part 2);Evidence 7 : Gene remnant
585034004855	putative arabinose transporter; Provisional; Region: PRK03545
585034004856	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034004857	putative substrate translocation pore; other site
585034004858	inner membrane protein; Provisional; Region: PRK10995
585034004859	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
585034004860	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
585034004861	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
585034004862	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034004863	hypothetical protein; Provisional; Region: PRK10106
585034004864	6-phospho-beta-glucosidase; Reviewed; Region: celA; PRK09589
585034004865	beta-galactosidase; Region: BGL; TIGR03356
585034004866	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
585034004867	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
585034004868	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
585034004869	trimer interface; other site
585034004870	sugar binding site [chemical binding]; other site
585034004871	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
585034004872	active site
585034004873	methionine cluster; other site
585034004874	phosphorylation site [posttranslational modification]
585034004875	metal binding site [ion binding]; metal-binding site
585034004876	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
585034004877	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
585034004878	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
585034004879	active site
585034004880	P-loop; other site
585034004881	phosphorylation site [posttranslational modification]
585034004882	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
585034004883	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034004884	DNA-binding site [nucleotide binding]; DNA binding site
585034004885	UTRA domain; Region: UTRA; pfam07702
585034004886	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
585034004887	EamA-like transporter family; Region: EamA; pfam00892
585034004888	EamA-like transporter family; Region: EamA; pfam00892
585034004889	putative transporter; Provisional; Region: PRK10054
585034004890	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034004891	putative substrate translocation pore; other site
585034004892	diguanylate cyclase; Provisional; Region: PRK09894
585034004893	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
585034004894	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585034004895	metal binding site [ion binding]; metal-binding site
585034004896	active site
585034004897	I-site; other site
585034004898	hypothetical protein; Provisional; Region: PRK10053
585034004899	hypothetical protein; Validated; Region: PRK03657
585034004900	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
585034004901	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
585034004902	active site
585034004903	Zn binding site [ion binding]; other site
585034004904	malonic semialdehyde reductase; Provisional; Region: PRK10538
585034004905	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
585034004906	putative NAD(P) binding site [chemical binding]; other site
585034004907	homodimer interface [polypeptide binding]; other site
585034004908	homotetramer interface [polypeptide binding]; other site
585034004909	active site
585034004910	Transcriptional regulators [Transcription]; Region: GntR; COG1802
585034004911	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034004912	DNA-binding site [nucleotide binding]; DNA binding site
585034004913	FCD domain; Region: FCD; pfam07729
585034004914	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
585034004915	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
585034004916	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
585034004917	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
585034004918	metabolite-proton symporter; Region: 2A0106; TIGR00883
585034004919	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034004920	putative substrate translocation pore; other site
585034004921	multiple promoter invertase; Provisional; Region: mpi; PRK13413
585034004922	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
585034004923	catalytic residues [active]
585034004924	catalytic nucleophile [active]
585034004925	Presynaptic Site I dimer interface [polypeptide binding]; other site
585034004926	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
585034004927	Synaptic Flat tetramer interface [polypeptide binding]; other site
585034004928	Synaptic Site I dimer interface [polypeptide binding]; other site
585034004929	DNA binding site [nucleotide binding]
585034004930	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
585034004931	DNA-binding interface [nucleotide binding]; DNA binding site
585034004932	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
585034004933	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
585034004934	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
585034004935	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
585034004936	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
585034004937	Phage Tail Collar Domain; Region: Collar; pfam07484
585034004938	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
585034004939	Phage-related protein, tail component [Function unknown]; Region: COG4733
585034004940	Putative phage tail protein; Region: Phage-tail_3; pfam13550
585034004941	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
585034004942	Fibronectin type III protein; Region: DUF3672; pfam12421
585034004943	Phage-related protein, tail component [Function unknown]; Region: COG4723
585034004944	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
585034004945	MPN+ (JAMM) motif; other site
585034004946	Zinc-binding site [ion binding]; other site
585034004947	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
585034004948	NlpC/P60 family; Region: NLPC_P60; cl17555
585034004949	fragment of Minor tail protein L (partial);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585034004950	Phage-related protein [Function unknown]; Region: COG4718
585034004951	Phage-related minor tail protein [Function unknown]; Region: COG5281
585034004952	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
585034004953	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
585034004954	Minor tail protein T; Region: Phage_tail_T; pfam06223
585034004955	phage minor tail protein G; Region: phage_lambda_G; TIGR01674
585034004956	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
585034004957	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
585034004958	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
585034004959	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
585034004960	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
585034004961	DNA packaging protein FI; Region: Packaging_FI; pfam14000
585034004962	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
585034004963	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
585034004964	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
585034004965	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
585034004966	tandem repeat interface [polypeptide binding]; other site
585034004967	oligomer interface [polypeptide binding]; other site
585034004968	active site residues [active]
585034004969	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
585034004970	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
585034004971	gpW; Region: gpW; pfam02831
585034004972	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
585034004973	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
585034004974	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
585034004975	Protein of unknown function (DUF1398); Region: DUF1398; pfam07166
585034004976	GnsA/GnsB family; Region: GnsAB; pfam08178
585034004977	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
585034004978	DNA-binding site [nucleotide binding]; DNA binding site
585034004979	RNA-binding motif; other site
585034004980	Protein of unknown function (DUF2514); Region: DUF2514; pfam10721
585034004981	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
585034004982	catalytic residues [active]
585034004983	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
585034004984	Lysis protein S; Region: Lysis_S; pfam04971
585034004985	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
585034004986	DNA-binding site [nucleotide binding]; DNA binding site
585034004987	RNA-binding motif; other site
585034004988	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
585034004989	DNA-binding site [nucleotide binding]; DNA binding site
585034004990	RNA-binding motif; other site
585034004991	Antitermination protein; Region: Antiterm; pfam03589
585034004992	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
585034004993	DnaJ central domain; Region: DnaJ_CXXCXGXG; pfam00684
585034004994	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
585034004995	Protein of unknown function (DUF968); Region: DUF968; pfam06147
585034004996	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
585034004997	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
585034004998	fragment of Conserved hypothetical protein (part 2);Evidence 7 : Gene remnant
585034004999	fragment of Conserved hypothetical protein (part 1);Evidence 7 : Gene remnant
585034005000	Methyltransferase domain; Region: Methyltransf_25; pfam13649
585034005001	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
585034005002	primosomal protein DnaI; Provisional; Region: PRK02854
585034005003	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
585034005004	DNA-binding transcriptional regulator DicC; Provisional; Region: PRK09744
585034005005	transcriptional repressor DicA; Reviewed; Region: PRK09706
585034005006	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585034005007	non-specific DNA binding site [nucleotide binding]; other site
585034005008	salt bridge; other site
585034005009	sequence-specific DNA binding site [nucleotide binding]; other site
585034005010	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
585034005011	DicB protein; Region: DicB; pfam05358
585034005012	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
585034005013	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
585034005014	active site
585034005015	catalytic site [active]
585034005016	substrate binding site [chemical binding]; other site
585034005017	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
585034005018	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
585034005019	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
585034005020	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
585034005021	Int/Topo IB signature motif; other site
585034005022	putative oxidoreductase; Provisional; Region: PRK10083
585034005023	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
585034005024	putative NAD(P) binding site [chemical binding]; other site
585034005025	catalytic Zn binding site [ion binding]; other site
585034005026	structural Zn binding site [ion binding]; other site
585034005027	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
585034005028	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
585034005029	putative active site pocket [active]
585034005030	putative metal binding site [ion binding]; other site
585034005031	hypothetical protein; Provisional; Region: PRK02237
585034005032	hypothetical protein; Provisional; Region: PRK13659
585034005033	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
585034005034	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585034005035	Coenzyme A binding pocket [chemical binding]; other site
585034005036	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
585034005037	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
585034005038	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
585034005039	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
585034005040	putative [Fe4-S4] binding site [ion binding]; other site
585034005041	putative molybdopterin cofactor binding site [chemical binding]; other site
585034005042	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
585034005043	putative molybdopterin cofactor binding site; other site
585034005044	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
585034005045	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
585034005046	putative [Fe4-S4] binding site [ion binding]; other site
585034005047	putative molybdopterin cofactor binding site [chemical binding]; other site
585034005048	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
585034005049	putative molybdopterin cofactor binding site; other site
585034005050	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
585034005051	4Fe-4S binding domain; Region: Fer4; cl02805
585034005052	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
585034005053	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
585034005054	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
585034005055	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
585034005056	Cl- selectivity filter; other site
585034005057	Cl- binding residues [ion binding]; other site
585034005058	pore gating glutamate residue; other site
585034005059	dimer interface [polypeptide binding]; other site
585034005060	putative dithiobiotin synthetase; Provisional; Region: PRK12374
585034005061	AAA domain; Region: AAA_26; pfam13500
585034005062	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
585034005063	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
585034005064	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
585034005065	nucleotide binding site [chemical binding]; other site
585034005066	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
585034005067	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034005068	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
585034005069	dimerization interface [polypeptide binding]; other site
585034005070	substrate binding pocket [chemical binding]; other site
585034005071	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
585034005072	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034005073	putative substrate translocation pore; other site
585034005074	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
585034005075	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
585034005076	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
585034005077	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
585034005078	Domain of unknown function DUF20; Region: UPF0118; pfam01594
585034005079	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
585034005080	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
585034005081	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
585034005082	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
585034005083	ligand binding site [chemical binding]; other site
585034005084	homodimer interface [polypeptide binding]; other site
585034005085	NAD(P) binding site [chemical binding]; other site
585034005086	trimer interface B [polypeptide binding]; other site
585034005087	trimer interface A [polypeptide binding]; other site
585034005088	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
585034005089	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
585034005090	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
585034005091	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
585034005092	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
585034005093	Spore germination protein; Region: Spore_permease; cl17796
585034005094	dihydromonapterin reductase; Provisional; Region: PRK06483
585034005095	pteridine reductase (PR), classical (c) SDRs; Region: PR_SDR_c; cd05357
585034005096	NADP binding site [chemical binding]; other site
585034005097	substrate binding pocket [chemical binding]; other site
585034005098	active site
585034005099	GlpM protein; Region: GlpM; pfam06942
585034005100	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
585034005101	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034005102	active site
585034005103	phosphorylation site [posttranslational modification]
585034005104	intermolecular recognition site; other site
585034005105	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585034005106	DNA binding site [nucleotide binding]
585034005107	sensor protein RstB; Provisional; Region: PRK10604
585034005108	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585034005109	dimerization interface [polypeptide binding]; other site
585034005110	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585034005111	dimer interface [polypeptide binding]; other site
585034005112	phosphorylation site [posttranslational modification]
585034005113	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034005114	ATP binding site [chemical binding]; other site
585034005115	Mg2+ binding site [ion binding]; other site
585034005116	G-X-G motif; other site
585034005117	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
585034005118	fumarate hydratase; Reviewed; Region: fumC; PRK00485
585034005119	Class II fumarases; Region: Fumarase_classII; cd01362
585034005120	active site
585034005121	tetramer interface [polypeptide binding]; other site
585034005122	fumarate hydratase; Provisional; Region: PRK15389
585034005123	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
585034005124	Fumarase C-terminus; Region: Fumerase_C; pfam05683
585034005125	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
585034005126	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
585034005127	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
585034005128	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
585034005129	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
585034005130	putative outer membrane porin protein; Provisional; Region: PRK11379
585034005131	glucuronide transporter; Provisional; Region: PRK09848
585034005132	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034005133	putative substrate translocation pore; other site
585034005134	beta-D-glucuronidase; Provisional; Region: PRK10150
585034005135	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
585034005136	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
585034005137	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
585034005138	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
585034005139	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585034005140	7-alpha-hydroxysteroid dehydrogenase; Validated; Region: PRK06113
585034005141	7 alpha-hydroxysteroid dehydrogenase (7 alpha-HSDH), classical (c) SDRs; Region: 7_alpha_HSDH_SDR_c; cd05365
585034005142	NAD binding site [chemical binding]; other site
585034005143	substrate binding site [chemical binding]; other site
585034005144	homotetramer interface [polypeptide binding]; other site
585034005145	homodimer interface [polypeptide binding]; other site
585034005146	active site
585034005147	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
585034005148	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585034005149	DNA binding site [nucleotide binding]
585034005150	domain linker motif; other site
585034005151	Ligand-binding domain of MalI, a transcription regulator of the maltose system of Escherichia coli and its close homologs from other bacteria; Region: PBP1_MalI_like; cd06289
585034005152	putative dimerization interface [polypeptide binding]; other site
585034005153	putative ligand binding site [chemical binding]; other site
585034005154	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
585034005155	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
585034005156	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
585034005157	active site turn [active]
585034005158	phosphorylation site [posttranslational modification]
585034005159	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
585034005160	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585034005161	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034005162	homodimer interface [polypeptide binding]; other site
585034005163	catalytic residue [active]
585034005164	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
585034005165	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
585034005166	active site
585034005167	purine riboside binding site [chemical binding]; other site
585034005168	putative oxidoreductase; Provisional; Region: PRK11579
585034005169	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
585034005170	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
585034005171	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
585034005172	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
585034005173	electron transport complex protein RsxA; Provisional; Region: PRK05151
585034005174	electron transport complex protein RnfB; Provisional; Region: PRK05113
585034005175	Putative Fe-S cluster; Region: FeS; pfam04060
585034005176	4Fe-4S binding domain; Region: Fer4; pfam00037
585034005177	electron transport complex protein RnfC; Provisional; Region: PRK05035
585034005178	SLBB domain; Region: SLBB; pfam10531
585034005179	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
585034005180	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
585034005181	electron transport complex protein RnfG; Validated; Region: PRK01908
585034005182	electron transport complex RsxE subunit; Provisional; Region: PRK12405
585034005183	endonuclease III; Provisional; Region: PRK10702
585034005184	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
585034005185	minor groove reading motif; other site
585034005186	helix-hairpin-helix signature motif; other site
585034005187	substrate binding pocket [chemical binding]; other site
585034005188	active site
585034005189	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
585034005190	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
585034005191	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034005192	putative substrate translocation pore; other site
585034005193	POT family; Region: PTR2; pfam00854
585034005194	glutathionine S-transferase; Provisional; Region: PRK10542
585034005195	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
585034005196	C-terminal domain interface [polypeptide binding]; other site
585034005197	GSH binding site (G-site) [chemical binding]; other site
585034005198	dimer interface [polypeptide binding]; other site
585034005199	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
585034005200	N-terminal domain interface [polypeptide binding]; other site
585034005201	dimer interface [polypeptide binding]; other site
585034005202	substrate binding pocket (H-site) [chemical binding]; other site
585034005203	pyridoxamine kinase; Validated; Region: PRK05756
585034005204	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
585034005205	dimer interface [polypeptide binding]; other site
585034005206	pyridoxal binding site [chemical binding]; other site
585034005207	ATP binding site [chemical binding]; other site
585034005208	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
585034005209	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
585034005210	active site
585034005211	HIGH motif; other site
585034005212	dimer interface [polypeptide binding]; other site
585034005213	KMSKS motif; other site
585034005214	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
585034005215	RNA binding surface [nucleotide binding]; other site
585034005216	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
585034005217	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
585034005218	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
585034005219	lysozyme inhibitor; Provisional; Region: PRK11372
585034005220	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
585034005221	Uncharacterized protein family (UPF0075); Region: UPF0075; pfam03702
585034005222	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
585034005223	transcriptional regulator SlyA; Provisional; Region: PRK03573
585034005224	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
585034005225	Protein of unknown function (DUF1656); Region: DUF1656; cl11658
585034005226	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
585034005227	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585034005228	HlyD family secretion protein; Region: HlyD_3; pfam13437
585034005229	Fusaric acid resistance protein family; Region: FUSC; pfam04632
585034005230	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
585034005231	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
585034005232	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
585034005233	E-class dimer interface [polypeptide binding]; other site
585034005234	P-class dimer interface [polypeptide binding]; other site
585034005235	active site
585034005236	Cu2+ binding site [ion binding]; other site
585034005237	Zn2+ binding site [ion binding]; other site
585034005238	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
585034005239	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
585034005240	active site
585034005241	catalytic tetrad [active]
585034005242	Predicted Fe-S protein [General function prediction only]; Region: COG3313
585034005243	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
585034005244	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585034005245	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
585034005246	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
585034005247	FMN binding site [chemical binding]; other site
585034005248	active site
585034005249	substrate binding site [chemical binding]; other site
585034005250	catalytic residue [active]
585034005251	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
585034005252	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
585034005253	dimer interface [polypeptide binding]; other site
585034005254	active site
585034005255	metal binding site [ion binding]; metal-binding site
585034005256	glutathione binding site [chemical binding]; other site
585034005257	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
585034005258	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
585034005259	dimer interface [polypeptide binding]; other site
585034005260	catalytic site [active]
585034005261	putative active site [active]
585034005262	putative substrate binding site [chemical binding]; other site
585034005263	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585034005264	putative ATP-dependent helicase Lhr; Provisional; Region: PRK09751
585034005265	ATP binding site [chemical binding]; other site
585034005266	putative Mg++ binding site [ion binding]; other site
585034005267	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585034005268	nucleotide binding region [chemical binding]; other site
585034005269	ATP-binding site [chemical binding]; other site
585034005270	DEAD/H associated; Region: DEAD_assoc; pfam08494
585034005271	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
585034005272	putative GSH binding site [chemical binding]; other site
585034005273	catalytic residues [active]
585034005274	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
585034005275	NlpC/P60 family; Region: NLPC_P60; pfam00877
585034005276	superoxide dismutase; Provisional; Region: PRK10543
585034005277	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
585034005278	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
585034005279	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034005280	Major Facilitator Superfamily; Region: MFS_1; pfam07690
585034005281	putative substrate translocation pore; other site
585034005282	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
585034005283	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585034005284	DNA binding site [nucleotide binding]
585034005285	domain linker motif; other site
585034005286	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
585034005287	dimerization interface [polypeptide binding]; other site
585034005288	ligand binding site [chemical binding]; other site
585034005289	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
585034005290	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034005291	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
585034005292	dimerization interface [polypeptide binding]; other site
585034005293	putative transporter; Provisional; Region: PRK11043
585034005294	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034005295	putative substrate translocation pore; other site
585034005296	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
585034005297	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
585034005298	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034005299	S-adenosylmethionine binding site [chemical binding]; other site
585034005300	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
585034005301	Lumazine binding domain; Region: Lum_binding; pfam00677
585034005302	Lumazine binding domain; Region: Lum_binding; pfam00677
585034005303	multidrug efflux protein; Reviewed; Region: PRK01766
585034005304	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
585034005305	cation binding site [ion binding]; other site
585034005306	hypothetical protein; Provisional; Region: PRK09945
585034005307	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
585034005308	putative monooxygenase; Provisional; Region: PRK11118
585034005309	hypothetical protein; Provisional; Region: PRK09897
585034005310	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
585034005311	hypothetical protein; Provisional; Region: PRK09946
585034005312	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
585034005313	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
585034005314	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
585034005315	hypothetical protein; Provisional; Region: PRK09947
585034005316	putative oxidoreductase; Provisional; Region: PRK09849
585034005317	Aldehyde ferredoxin oxidoreductase, N-terminal domain; Region: AFOR_N; pfam02730
585034005318	Aldehyde ferredoxin oxidoreductase, domains 2 & 3; Region: AFOR_C; pfam01314
585034005319	hypothetical protein; Provisional; Region: PRK09898
585034005320	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
585034005321	hypothetical protein; Provisional; Region: PRK10292
585034005322	pyruvate kinase; Provisional; Region: PRK09206
585034005323	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
585034005324	domain interfaces; other site
585034005325	active site
585034005326	murein lipoprotein; Provisional; Region: PRK15396
585034005327	L,D-transpeptidase; Provisional; Region: PRK10190
585034005328	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
585034005329	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
585034005330	cysteine desufuration protein SufE; Provisional; Region: PRK09296
585034005331	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
585034005332	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
585034005333	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
585034005334	catalytic residue [active]
585034005335	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
585034005336	FeS assembly protein SufD; Region: sufD; TIGR01981
585034005337	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
585034005338	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
585034005339	Walker A/P-loop; other site
585034005340	ATP binding site [chemical binding]; other site
585034005341	Q-loop/lid; other site
585034005342	ABC transporter signature motif; other site
585034005343	Walker B; other site
585034005344	D-loop; other site
585034005345	H-loop/switch region; other site
585034005346	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
585034005347	putative ABC transporter; Region: ycf24; CHL00085
585034005348	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
585034005349	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
585034005350	CoenzymeA binding site [chemical binding]; other site
585034005351	subunit interaction site [polypeptide binding]; other site
585034005352	PHB binding site; other site
585034005353	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
585034005354	FAD binding domain; Region: FAD_binding_4; pfam01565
585034005355	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
585034005356	putative inner membrane protein; Provisional; Region: PRK10983
585034005357	Domain of unknown function DUF20; Region: UPF0118; pfam01594
585034005358	Domain of unknown function (DUF1870); Region: DUF1870; pfam08965
585034005359	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034005360	Major Facilitator Superfamily; Region: MFS_1; pfam07690
585034005361	putative substrate translocation pore; other site
585034005362	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034005363	putative substrate translocation pore; other site
585034005364	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
585034005365	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
585034005366	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
585034005367	shikimate binding site; other site
585034005368	NAD(P) binding site [chemical binding]; other site
585034005369	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
585034005370	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
585034005371	active site
585034005372	catalytic residue [active]
585034005373	dimer interface [polypeptide binding]; other site
585034005374	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
585034005375	Coenzyme A transferase; Region: CoA_trans; smart00882
585034005376	Coenzyme A transferase; Region: CoA_trans; cl17247
585034005377	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
585034005378	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
585034005379	active site
585034005380	Cupin domain; Region: Cupin_2; pfam07883
585034005381	Winged helix DNA-binding domain (DUF1495); Region: DUF1495; cl01336
585034005382	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
585034005383	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034005384	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
585034005385	Ligand binding site [chemical binding]; other site
585034005386	Electron transfer flavoprotein domain; Region: ETF; pfam01012
585034005387	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
585034005388	Electron transfer flavoprotein domain; Region: ETF; smart00893
585034005389	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
585034005390	oxidoreductase; Provisional; Region: PRK10015
585034005391	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
585034005392	short chain acyl-CoA synthetase; Reviewed; Region: PRK06087
585034005393	Cyclohexanecarboxylate-CoA ligase (also called cyclohex-1-ene-1-carboxylate:CoA ligase); Region: CHC_CoA_lg; cd05903
585034005394	acyl-activating enzyme (AAE) consensus motif; other site
585034005395	putative AMP binding site [chemical binding]; other site
585034005396	putative active site [active]
585034005397	putative CoA binding site [chemical binding]; other site
585034005398	phosphoenolpyruvate synthase; Validated; Region: PRK06464
585034005399	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
585034005400	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
585034005401	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
585034005402	PEP synthetase regulatory protein; Provisional; Region: PRK05339
585034005403	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
585034005404	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
585034005405	Hemin uptake protein [Inorganic ion transport and metabolism]; Region: HemP; COG4256
585034005406	fragment of conserved hypothetical protein (part 2);Evidence 7 : Gene remnant
585034005407	fragment of conserved hypothetical protein (part 1);Evidence 7 : Gene remnant
585034005408	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
585034005409	NlpC/P60 family; Region: NLPC_P60; pfam00877
585034005410	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
585034005411	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
585034005412	Walker A/P-loop; other site
585034005413	ATP binding site [chemical binding]; other site
585034005414	Q-loop/lid; other site
585034005415	ABC transporter signature motif; other site
585034005416	Walker B; other site
585034005417	D-loop; other site
585034005418	H-loop/switch region; other site
585034005419	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
585034005420	catalytic residues [active]
585034005421	dimer interface [polypeptide binding]; other site
585034005422	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
585034005423	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
585034005424	ABC-ATPase subunit  interface; other site
585034005425	dimer interface [polypeptide binding]; other site
585034005426	putative PBP binding regions; other site
585034005427	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
585034005428	IHF dimer interface [polypeptide binding]; other site
585034005429	IHF - DNA interface [nucleotide binding]; other site
585034005430	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
585034005431	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
585034005432	putative tRNA-binding site [nucleotide binding]; other site
585034005433	B3/4 domain; Region: B3_4; pfam03483
585034005434	tRNA synthetase B5 domain; Region: B5; smart00874
585034005435	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
585034005436	dimer interface [polypeptide binding]; other site
585034005437	motif 1; other site
585034005438	motif 3; other site
585034005439	motif 2; other site
585034005440	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
585034005441	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
585034005442	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
585034005443	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
585034005444	dimer interface [polypeptide binding]; other site
585034005445	motif 1; other site
585034005446	active site
585034005447	motif 2; other site
585034005448	motif 3; other site
585034005449	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
585034005450	23S rRNA binding site [nucleotide binding]; other site
585034005451	L21 binding site [polypeptide binding]; other site
585034005452	L13 binding site [polypeptide binding]; other site
585034005453	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
585034005454	fragment of protein chain initiation factor IF-3 (partial);Evidence 7 : Gene remnant; Product type f : factor
585034005455	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
585034005456	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
585034005457	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
585034005458	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
585034005459	active site
585034005460	dimer interface [polypeptide binding]; other site
585034005461	motif 1; other site
585034005462	motif 2; other site
585034005463	motif 3; other site
585034005464	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
585034005465	anticodon binding site; other site
585034005466	Fragment of putative regulatory protein with ankyrin repeats ArpB (Part 1);Evidence 7 : Gene remnant; Product type pr : putative regulator
585034005467	fragment of putative ankyrin repeat regulatory protein (part 1);Evidence 7 : Gene remnant; Product type pr : putative regulator
585034005468	fragment of putative ankyrin repeat regulatory protein (part 2);Evidence 7 : Gene remnant; Product type pr : putative regulator
585034005469	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
585034005470	6-phosphofructokinase 2; Provisional; Region: PRK10294
585034005471	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
585034005472	putative substrate binding site [chemical binding]; other site
585034005473	putative ATP binding site [chemical binding]; other site
585034005474	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
585034005475	Phosphotransferase enzyme family; Region: APH; pfam01636
585034005476	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
585034005477	active site
585034005478	ATP binding site [chemical binding]; other site
585034005479	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
585034005480	YniB-like protein; Region: YniB; pfam14002
585034005481	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
585034005482	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
585034005483	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034005484	motif II; other site
585034005485	inner membrane protein; Provisional; Region: PRK11648
585034005486	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
585034005487	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
585034005488	fragment of conserved hypothetical protein (part 2);Evidence 7 : Gene remnant
585034005489	fragment of conserved hypothetical protein (part 1);Evidence 7 : Gene remnant
585034005490	cell division modulator; Provisional; Region: PRK10113
585034005491	hydroperoxidase II; Provisional; Region: katE; PRK11249
585034005492	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
585034005493	tetramer interface [polypeptide binding]; other site
585034005494	heme binding pocket [chemical binding]; other site
585034005495	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
585034005496	domain interactions; other site
585034005497	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
585034005498	putative active site [active]
585034005499	YdjC motif; other site
585034005500	Mg binding site [ion binding]; other site
585034005501	putative homodimer interface [polypeptide binding]; other site
585034005502	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
585034005503	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
585034005504	NAD binding site [chemical binding]; other site
585034005505	sugar binding site [chemical binding]; other site
585034005506	divalent metal binding site [ion binding]; other site
585034005507	tetramer (dimer of dimers) interface [polypeptide binding]; other site
585034005508	dimer interface [polypeptide binding]; other site
585034005509	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
585034005510	Cupin domain; Region: Cupin_2; pfam07883
585034005511	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034005512	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
585034005513	methionine cluster; other site
585034005514	active site
585034005515	phosphorylation site [posttranslational modification]
585034005516	metal binding site [ion binding]; metal-binding site
585034005517	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
585034005518	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
585034005519	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
585034005520	active site
585034005521	P-loop; other site
585034005522	phosphorylation site [posttranslational modification]
585034005523	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
585034005524	NAD+ synthetase; Region: nadE; TIGR00552
585034005525	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
585034005526	homodimer interface [polypeptide binding]; other site
585034005527	NAD binding pocket [chemical binding]; other site
585034005528	ATP binding pocket [chemical binding]; other site
585034005529	Mg binding site [ion binding]; other site
585034005530	active-site loop [active]
585034005531	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
585034005532	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
585034005533	GIY-YIG motif/motif A; other site
585034005534	active site
585034005535	catalytic site [active]
585034005536	putative DNA binding site [nucleotide binding]; other site
585034005537	metal binding site [ion binding]; metal-binding site
585034005538	hypothetical protein; Provisional; Region: PRK11396
585034005539	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
585034005540	dimer interface [polypeptide binding]; other site
585034005541	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
585034005542	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
585034005543	putative active site [active]
585034005544	Zn binding site [ion binding]; other site
585034005545	succinylarginine dihydrolase; Provisional; Region: PRK13281
585034005546	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
585034005547	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
585034005548	NAD(P) binding site [chemical binding]; other site
585034005549	catalytic residues [active]
585034005550	arginine succinyltransferase; Provisional; Region: PRK10456
585034005551	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
585034005552	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
585034005553	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
585034005554	inhibitor-cofactor binding pocket; inhibition site
585034005555	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034005556	catalytic residue [active]
585034005557	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
585034005558	putative catalytic site [active]
585034005559	putative phosphate binding site [ion binding]; other site
585034005560	active site
585034005561	metal binding site A [ion binding]; metal-binding site
585034005562	DNA binding site [nucleotide binding]
585034005563	putative AP binding site [nucleotide binding]; other site
585034005564	putative metal binding site B [ion binding]; other site
585034005565	Uncharacterized conserved protein [Function unknown]; Region: COG0398
585034005566	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
585034005567	Uncharacterized conserved protein [Function unknown]; Region: COG0398
585034005568	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
585034005569	Uncharacterized conserved protein [Function unknown]; Region: COG2128
585034005570	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
585034005571	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4134
585034005572	hypothetical protein; Provisional; Region: PRK11622
585034005573	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4135
585034005574	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034005575	dimer interface [polypeptide binding]; other site
585034005576	conserved gate region; other site
585034005577	putative PBP binding loops; other site
585034005578	ABC-ATPase subunit interface; other site
585034005579	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4136
585034005580	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585034005581	Walker A/P-loop; other site
585034005582	ATP binding site [chemical binding]; other site
585034005583	Q-loop/lid; other site
585034005584	ABC transporter signature motif; other site
585034005585	Walker B; other site
585034005586	D-loop; other site
585034005587	H-loop/switch region; other site
585034005588	Rhodanese Homology Domain; Region: RHOD; smart00450
585034005589	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
585034005590	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
585034005591	active site residue [active]
585034005592	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
585034005593	active site residue [active]
585034005594	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
585034005595	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
585034005596	active site
585034005597	8-oxo-dGMP binding site [chemical binding]; other site
585034005598	nudix motif; other site
585034005599	metal binding site [ion binding]; metal-binding site
585034005600	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
585034005601	glutamate dehydrogenase; Provisional; Region: PRK09414
585034005602	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
585034005603	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
585034005604	NAD(P) binding site [chemical binding]; other site
585034005605	hypothetical protein; Provisional; Region: PRK11380
585034005606	DNA topoisomerase III; Provisional; Region: PRK07726
585034005607	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
585034005608	active site
585034005609	putative interdomain interaction site [polypeptide binding]; other site
585034005610	putative metal-binding site [ion binding]; other site
585034005611	putative nucleotide binding site [chemical binding]; other site
585034005612	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
585034005613	domain I; other site
585034005614	DNA binding groove [nucleotide binding]
585034005615	phosphate binding site [ion binding]; other site
585034005616	domain II; other site
585034005617	domain III; other site
585034005618	nucleotide binding site [chemical binding]; other site
585034005619	catalytic site [active]
585034005620	domain IV; other site
585034005621	selenophosphate synthetase; Provisional; Region: PRK00943
585034005622	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
585034005623	dimerization interface [polypeptide binding]; other site
585034005624	putative ATP binding site [chemical binding]; other site
585034005625	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
585034005626	putative FMN binding site [chemical binding]; other site
585034005627	protease 4; Provisional; Region: PRK10949
585034005628	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
585034005629	tandem repeat interface [polypeptide binding]; other site
585034005630	oligomer interface [polypeptide binding]; other site
585034005631	active site residues [active]
585034005632	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
585034005633	tandem repeat interface [polypeptide binding]; other site
585034005634	oligomer interface [polypeptide binding]; other site
585034005635	active site residues [active]
585034005636	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
585034005637	active site
585034005638	homodimer interface [polypeptide binding]; other site
585034005639	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
585034005640	Isochorismatase family; Region: Isochorismatase; pfam00857
585034005641	catalytic triad [active]
585034005642	metal binding site [ion binding]; metal-binding site
585034005643	conserved cis-peptide bond; other site
585034005644	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
585034005645	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034005646	putative substrate translocation pore; other site
585034005647	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034005648	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
585034005649	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
585034005650	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585034005651	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
585034005652	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
585034005653	active site
585034005654	catalytic tetrad [active]
585034005655	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
585034005656	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
585034005657	substrate binding site [chemical binding]; other site
585034005658	ATP binding site [chemical binding]; other site
585034005659	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
585034005660	intersubunit interface [polypeptide binding]; other site
585034005661	active site
585034005662	zinc binding site [ion binding]; other site
585034005663	Na+ binding site [ion binding]; other site
585034005664	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
585034005665	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
585034005666	inhibitor binding site; inhibition site
585034005667	catalytic Zn binding site [ion binding]; other site
585034005668	structural Zn binding site [ion binding]; other site
585034005669	NADP binding site [chemical binding]; other site
585034005670	tetramer interface [polypeptide binding]; other site
585034005671	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034005672	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034005673	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
585034005674	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH4; cd08258
585034005675	putative NAD(P) binding site [chemical binding]; other site
585034005676	catalytic Zn binding site [ion binding]; other site
585034005677	structural Zn binding site [ion binding]; other site
585034005678	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
585034005679	methionine sulfoxide reductase B; Provisional; Region: PRK00222
585034005680	SelR domain; Region: SelR; pfam01641
585034005681	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
585034005682	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
585034005683	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
585034005684	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
585034005685	active site
585034005686	phosphate binding residues; other site
585034005687	catalytic residues [active]
585034005688	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
585034005689	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
585034005690	active site
585034005691	catalytic tetrad [active]
585034005692	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
585034005693	PrkA family serine protein kinase; Provisional; Region: PRK15455
585034005694	AAA ATPase domain; Region: AAA_16; pfam13191
585034005695	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
585034005696	hypothetical protein; Provisional; Region: PRK05325
585034005697	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
585034005698	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585034005699	metal binding site [ion binding]; metal-binding site
585034005700	active site
585034005701	I-site; other site
585034005702	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
585034005703	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585034005704	metal binding site [ion binding]; metal-binding site
585034005705	active site
585034005706	I-site; other site
585034005707	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
585034005708	putative deacylase active site [active]
585034005709	Predicted membrane protein [Function unknown]; Region: COG2707
585034005710	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
585034005711	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034005712	cyanate transporter; Region: CynX; TIGR00896
585034005713	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034005714	putative substrate translocation pore; other site
585034005715	Uncharacterized conserved protein [Function unknown]; Region: COG3189
585034005716	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
585034005717	Domain of unknown function (DUF333); Region: DUF333; pfam03891
585034005718	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
585034005719	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
585034005720	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
585034005721	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585034005722	metal binding site [ion binding]; metal-binding site
585034005723	active site
585034005724	I-site; other site
585034005725	hypothetical protein; Provisional; Region: PRK10457
585034005726	Importin beta-related nuclear transport receptor [Nuclear structure / Intracellular trafficking and secretion]; Region: CRM1; COG5101
585034005727	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
585034005728	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
585034005729	Probable transposase; Region: OrfB_IS605; pfam01385
585034005730	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
585034005731	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
585034005732	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
585034005733	leucine export protein LeuE; Provisional; Region: PRK10958
585034005734	transcriptional activator TtdR; Provisional; Region: PRK09801
585034005735	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034005736	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
585034005737	putative effector binding pocket; other site
585034005738	putative dimerization interface [polypeptide binding]; other site
585034005739	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
585034005740	tartrate dehydrogenase; Region: TTC; TIGR02089
585034005741	putative transporter; Provisional; Region: PRK09950
585034005742	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
585034005743	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
585034005744	[2Fe-2S] cluster binding site [ion binding]; other site
585034005745	C-terminal catalytic domain of the oxygenase alpha subunit of an uncharacterized subgroup of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases; Region: RHO_alpha_C_2; cd08886
585034005746	putative alpha subunit interface [polypeptide binding]; other site
585034005747	putative active site [active]
585034005748	putative substrate binding site [chemical binding]; other site
585034005749	Fe binding site [ion binding]; other site
585034005750	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
585034005751	Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal  ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185
585034005752	FMN-binding pocket [chemical binding]; other site
585034005753	flavin binding motif; other site
585034005754	phosphate binding motif [ion binding]; other site
585034005755	beta-alpha-beta structure motif; other site
585034005756	NAD binding pocket [chemical binding]; other site
585034005757	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
585034005758	catalytic loop [active]
585034005759	iron binding site [ion binding]; other site
585034005760	ribonuclease D; Provisional; Region: PRK10829
585034005761	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
585034005762	catalytic site [active]
585034005763	putative active site [active]
585034005764	putative substrate binding site [chemical binding]; other site
585034005765	Helicase and RNase D C-terminal; Region: HRDC; smart00341
585034005766	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
585034005767	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
585034005768	acyl-activating enzyme (AAE) consensus motif; other site
585034005769	putative AMP binding site [chemical binding]; other site
585034005770	putative active site [active]
585034005771	putative CoA binding site [chemical binding]; other site
585034005772	outer membrane lipoprotein, Slp family; Region: slp; TIGR00752
585034005773	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
585034005774	Glycoprotease family; Region: Peptidase_M22; pfam00814
585034005775	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
585034005776	DEAD/DEAH box helicase; Region: DEAD; pfam00270
585034005777	ATP binding site [chemical binding]; other site
585034005778	DEAD_2; Region: DEAD_2; pfam06733
585034005779	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
585034005780	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
585034005781	homotrimer interaction site [polypeptide binding]; other site
585034005782	putative active site [active]
585034005783	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
585034005784	hypothetical protein; Provisional; Region: PRK05114
585034005785	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
585034005786	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
585034005787	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
585034005788	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
585034005789	putative active site [active]
585034005790	putative CoA binding site [chemical binding]; other site
585034005791	nudix motif; other site
585034005792	metal binding site [ion binding]; metal-binding site
585034005793	L-serine deaminase; Provisional; Region: PRK15023
585034005794	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
585034005795	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
585034005796	phage resistance protein; Provisional; Region: PRK10551
585034005797	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
585034005798	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585034005799	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
585034005800	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
585034005801	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
585034005802	Transporter associated domain; Region: CorC_HlyC; smart01091
585034005803	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
585034005804	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
585034005805	active pocket/dimerization site; other site
585034005806	active site
585034005807	phosphorylation site [posttranslational modification]
585034005808	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
585034005809	active site
585034005810	phosphorylation site [posttranslational modification]
585034005811	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
585034005812	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
585034005813	Predicted membrane protein [Function unknown]; Region: COG4811
585034005814	hypothetical protein; Provisional; Region: PRK11469
585034005815	Domain of unknown function DUF; Region: DUF204; pfam02659
585034005816	Domain of unknown function DUF; Region: DUF204; pfam02659
585034005817	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
585034005818	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034005819	S-adenosylmethionine binding site [chemical binding]; other site
585034005820	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
585034005821	DNA-binding site [nucleotide binding]; DNA binding site
585034005822	RNA-binding motif; other site
585034005823	Protein of unknown function (DUF2627); Region: DUF2527; pfam10736
585034005824	YebO-like protein; Region: YebO; pfam13974
585034005825	PhoPQ regulatory protein; Provisional; Region: PRK10299
585034005826	YobH-like protein; Region: YobH; pfam13996
585034005827	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
585034005828	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
585034005829	dimerization interface [polypeptide binding]; other site
585034005830	putative Zn2+ binding site [ion binding]; other site
585034005831	putative DNA binding site [nucleotide binding]; other site
585034005832	Bacterial transcriptional regulator; Region: IclR; pfam01614
585034005833	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034005834	Major Facilitator Superfamily; Region: MFS_1; pfam07690
585034005835	putative substrate translocation pore; other site
585034005836	Predicted integral membrane protein [Function unknown]; Region: COG5521
585034005837	heat shock protein HtpX; Provisional; Region: PRK05457
585034005838	carboxy-terminal protease; Provisional; Region: PRK11186
585034005839	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
585034005840	protein binding site [polypeptide binding]; other site
585034005841	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
585034005842	Catalytic dyad [active]
585034005843	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
585034005844	ProP expression regulator; Provisional; Region: PRK04950
585034005845	ProQ/FINO family; Region: ProQ; pfam04352
585034005846	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
585034005847	GAF domain; Region: GAF_2; pfam13185
585034005848	integral membrane protein, PqiA family; Region: pqiA_fam; TIGR00155
585034005849	Paraquat-inducible protein A; Region: PqiA; pfam04403
585034005850	Paraquat-inducible protein A; Region: PqiA; pfam04403
585034005851	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
585034005852	mce related protein; Region: MCE; pfam02470
585034005853	mce related protein; Region: MCE; pfam02470
585034005854	mce related protein; Region: MCE; pfam02470
585034005855	mce related protein; Region: MCE; pfam02470
585034005856	mce related protein; Region: MCE; pfam02470
585034005857	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
585034005858	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034005859	S-adenosylmethionine binding site [chemical binding]; other site
585034005860	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
585034005861	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
585034005862	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
585034005863	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
585034005864	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
585034005865	active site
585034005866	metal binding site [ion binding]; metal-binding site
585034005867	fragment of conserved hypothetical protein (partial);Evidence 7 : Gene remnant
585034005868	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
585034005869	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
585034005870	hypothetical protein; Provisional; Region: PRK10301
585034005871	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
585034005872	Predicted amidohydrolase [General function prediction only]; Region: COG0388
585034005873	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
585034005874	exodeoxyribonuclease X; Provisional; Region: PRK07983
585034005875	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
585034005876	active site
585034005877	catalytic site [active]
585034005878	substrate binding site [chemical binding]; other site
585034005879	protease 2; Provisional; Region: PRK10115
585034005880	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
585034005881	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
585034005882	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
585034005883	putative metal binding site [ion binding]; other site
585034005884	hypothetical protein; Provisional; Region: PRK13680
585034005885	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
585034005886	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
585034005887	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
585034005888	ATP-grasp domain; Region: ATP-grasp; pfam02222
585034005889	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
585034005890	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
585034005891	active site
585034005892	intersubunit interface [polypeptide binding]; other site
585034005893	catalytic residue [active]
585034005894	phosphogluconate dehydratase; Validated; Region: PRK09054
585034005895	6-phosphogluconate dehydratase; Region: edd; TIGR01196
585034005896	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
585034005897	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
585034005898	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
585034005899	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
585034005900	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
585034005901	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
585034005902	putative active site [active]
585034005903	pyruvate kinase; Provisional; Region: PRK05826
585034005904	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
585034005905	domain interfaces; other site
585034005906	active site
585034005907	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
585034005908	Putative esterase; Region: Esterase; pfam00756
585034005909	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
585034005910	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618
585034005911	Amidohydrolase; Region: Amidohydro_2; pfam04909
585034005912	active site
585034005913	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
585034005914	homodimer interface [polypeptide binding]; other site
585034005915	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
585034005916	active site
585034005917	homodimer interface [polypeptide binding]; other site
585034005918	catalytic site [active]
585034005919	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
585034005920	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034005921	dimer interface [polypeptide binding]; other site
585034005922	conserved gate region; other site
585034005923	putative PBP binding loops; other site
585034005924	ABC-ATPase subunit interface; other site
585034005925	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
585034005926	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034005927	dimer interface [polypeptide binding]; other site
585034005928	conserved gate region; other site
585034005929	putative PBP binding loops; other site
585034005930	ABC-ATPase subunit interface; other site
585034005931	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
585034005932	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
585034005933	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
585034005934	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
585034005935	trimer interface [polypeptide binding]; other site
585034005936	active site
585034005937	UDP-GlcNAc binding site [chemical binding]; other site
585034005938	lipid binding site [chemical binding]; lipid-binding site
585034005939	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
585034005940	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
585034005941	Walker A/P-loop; other site
585034005942	ATP binding site [chemical binding]; other site
585034005943	Q-loop/lid; other site
585034005944	ABC transporter signature motif; other site
585034005945	Walker B; other site
585034005946	D-loop; other site
585034005947	H-loop/switch region; other site
585034005948	TOBE domain; Region: TOBE; pfam03459
585034005949	Sugar-specific transcriptional regulator TrmB; Region: TrmB; pfam01978
585034005950	Middle phospholipase D-like domain of the transcriptional regulator TrmB and similar proteins; Region: PLDc_like_TrmB_middle; cd09124
585034005951	C-terminal domain interface [polypeptide binding]; other site
585034005952	sugar binding site [chemical binding]; other site
585034005953	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
585034005954	N-terminal catalytic domain of endoplasmic reticulum(ER)/cytosolic class II alpha-mannosidases; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_ER_cytosolic; cd10789
585034005955	active site
585034005956	catalytic site [active]
585034005957	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; pfam09261
585034005958	Glycosyl hydrolases family 38 C-terminal domain; Region: Glyco_hydro_38C; pfam07748
585034005959	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
585034005960	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
585034005961	putative acyl-acceptor binding pocket; other site
585034005962	putative peptidase; Provisional; Region: PRK11649
585034005963	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
585034005964	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
585034005965	Peptidase family M23; Region: Peptidase_M23; pfam01551
585034005966	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
585034005967	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
585034005968	metal binding site [ion binding]; metal-binding site
585034005969	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
585034005970	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
585034005971	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
585034005972	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
585034005973	ABC-ATPase subunit  interface; other site
585034005974	dimer interface [polypeptide binding]; other site
585034005975	putative PBP binding regions; other site
585034005976	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
585034005977	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034005978	Walker A motif; other site
585034005979	ATP binding site [chemical binding]; other site
585034005980	Walker B motif; other site
585034005981	arginine finger; other site
585034005982	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
585034005983	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
585034005984	RuvA N terminal domain; Region: RuvA_N; pfam01330
585034005985	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
585034005986	hypothetical protein; Provisional; Region: PRK11470
585034005987	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
585034005988	active site
585034005989	putative DNA-binding cleft [nucleotide binding]; other site
585034005990	dimer interface [polypeptide binding]; other site
585034005991	hypothetical protein; Validated; Region: PRK00110
585034005992	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
585034005993	nudix motif; other site
585034005994	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
585034005995	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
585034005996	dimer interface [polypeptide binding]; other site
585034005997	anticodon binding site; other site
585034005998	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
585034005999	homodimer interface [polypeptide binding]; other site
585034006000	motif 1; other site
585034006001	active site
585034006002	motif 2; other site
585034006003	GAD domain; Region: GAD; pfam02938
585034006004	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
585034006005	motif 3; other site
585034006006	Isochorismatase family; Region: Isochorismatase; pfam00857
585034006007	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
585034006008	catalytic triad [active]
585034006009	conserved cis-peptide bond; other site
585034006010	hypothetical protein; Provisional; Region: PRK10302
585034006011	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
585034006012	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034006013	S-adenosylmethionine binding site [chemical binding]; other site
585034006014	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034006015	S-adenosylmethionine binding site [chemical binding]; other site
585034006016	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
585034006017	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
585034006018	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
585034006019	molybdopterin cofactor binding site [chemical binding]; other site
585034006020	substrate binding site [chemical binding]; other site
585034006021	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
585034006022	molybdopterin cofactor binding site; other site
585034006023	trimethylamine-N-oxide reductase c-type cytochrome TorC; Region: torC; TIGR02162
585034006024	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
585034006025	copper homeostasis protein CutC; Provisional; Region: PRK11572
585034006026	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
585034006027	putative metal binding site [ion binding]; other site
585034006028	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
585034006029	arginyl-tRNA synthetase; Region: argS; TIGR00456
585034006030	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
585034006031	active site
585034006032	HIGH motif; other site
585034006033	KMSK motif region; other site
585034006034	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
585034006035	tRNA binding surface [nucleotide binding]; other site
585034006036	anticodon binding site; other site
585034006037	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
585034006038	Flagellar protein FlhE; Region: FlhE; pfam06366
585034006039	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
585034006040	FHIPEP family; Region: FHIPEP; pfam00771
585034006041	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
585034006042	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
585034006043	chemotaxis regulator CheZ; Provisional; Region: PRK11166
585034006044	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
585034006045	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034006046	active site
585034006047	phosphorylation site [posttranslational modification]
585034006048	intermolecular recognition site; other site
585034006049	dimerization interface [polypeptide binding]; other site
585034006050	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
585034006051	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034006052	active site
585034006053	phosphorylation site [posttranslational modification]
585034006054	intermolecular recognition site; other site
585034006055	dimerization interface [polypeptide binding]; other site
585034006056	CheB methylesterase; Region: CheB_methylest; pfam01339
585034006057	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
585034006058	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
585034006059	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034006060	S-adenosylmethionine binding site [chemical binding]; other site
585034006061	methyl-accepting protein IV; Provisional; Region: PRK09793
585034006062	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
585034006063	dimer interface [polypeptide binding]; other site
585034006064	ligand binding site [chemical binding]; other site
585034006065	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585034006066	dimerization interface [polypeptide binding]; other site
585034006067	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
585034006068	dimer interface [polypeptide binding]; other site
585034006069	putative CheW interface [polypeptide binding]; other site
585034006070	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
585034006071	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
585034006072	dimer interface [polypeptide binding]; other site
585034006073	ligand binding site [chemical binding]; other site
585034006074	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585034006075	dimerization interface [polypeptide binding]; other site
585034006076	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
585034006077	dimer interface [polypeptide binding]; other site
585034006078	putative CheW interface [polypeptide binding]; other site
585034006079	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
585034006080	putative CheA interaction surface; other site
585034006081	chemotaxis protein CheA; Provisional; Region: PRK10547
585034006082	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
585034006083	putative binding surface; other site
585034006084	active site
585034006085	CheY binding; Region: CheY-binding; pfam09078
585034006086	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
585034006087	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034006088	ATP binding site [chemical binding]; other site
585034006089	Mg2+ binding site [ion binding]; other site
585034006090	G-X-G motif; other site
585034006091	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
585034006092	flagellar motor protein MotB; Validated; Region: motB; PRK09041
585034006093	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
585034006094	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
585034006095	ligand binding site [chemical binding]; other site
585034006096	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
585034006097	flagellar motor protein MotA; Validated; Region: PRK09110
585034006098	transcriptional activator FlhC; Provisional; Region: PRK12722
585034006099	transcriptional activator FlhD; Provisional; Region: PRK02909
585034006100	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
585034006101	Ligand Binding Site [chemical binding]; other site
585034006102	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
585034006103	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
585034006104	active site
585034006105	homotetramer interface [polypeptide binding]; other site
585034006106	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
585034006107	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
585034006108	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585034006109	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585034006110	TM-ABC transporter signature motif; other site
585034006111	L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288
585034006112	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
585034006113	Walker A/P-loop; other site
585034006114	ATP binding site [chemical binding]; other site
585034006115	Q-loop/lid; other site
585034006116	ABC transporter signature motif; other site
585034006117	Walker B; other site
585034006118	D-loop; other site
585034006119	H-loop/switch region; other site
585034006120	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
585034006121	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
585034006122	Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540
585034006123	ligand binding site [chemical binding]; other site
585034006124	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
585034006125	Ferritin-like domain; Region: Ferritin; pfam00210
585034006126	ferroxidase diiron center [ion binding]; other site
585034006127	Protein of unknown function (DUF2766); Region: DUF2766; pfam10964
585034006128	YecR-like lipoprotein; Region: YecR; pfam13992
585034006129	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
585034006130	Ferritin-like domain; Region: Ferritin; pfam00210
585034006131	ferroxidase diiron center [ion binding]; other site
585034006132	probable metal-binding protein; Region: matur_matur; TIGR03853
585034006133	tyrosine transporter TyrP; Provisional; Region: PRK15132
585034006134	aromatic amino acid transport protein; Region: araaP; TIGR00837
585034006135	hypothetical protein; Provisional; Region: PRK10396
585034006136	yecA family protein; Region: ygfB_yecA; TIGR02292
585034006137	SEC-C motif; Region: SEC-C; pfam02810
585034006138	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
585034006139	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
585034006140	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
585034006141	GIY-YIG motif/motif A; other site
585034006142	active site
585034006143	catalytic site [active]
585034006144	putative DNA binding site [nucleotide binding]; other site
585034006145	metal binding site [ion binding]; metal-binding site
585034006146	UvrB/uvrC motif; Region: UVR; pfam02151
585034006147	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
585034006148	Helix-hairpin-helix motif; Region: HHH; pfam00633
585034006149	response regulator; Provisional; Region: PRK09483
585034006150	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034006151	active site
585034006152	phosphorylation site [posttranslational modification]
585034006153	intermolecular recognition site; other site
585034006154	dimerization interface [polypeptide binding]; other site
585034006155	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585034006156	DNA binding residues [nucleotide binding]
585034006157	dimerization interface [polypeptide binding]; other site
585034006158	hypothetical protein; Provisional; Region: PRK10613
585034006159	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
585034006160	Autoinducer binding domain; Region: Autoind_bind; pfam03472
585034006161	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585034006162	DNA binding residues [nucleotide binding]
585034006163	dimerization interface [polypeptide binding]; other site
585034006164	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
585034006165	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
585034006166	Walker A/P-loop; other site
585034006167	ATP binding site [chemical binding]; other site
585034006168	Q-loop/lid; other site
585034006169	ABC transporter signature motif; other site
585034006170	Walker B; other site
585034006171	D-loop; other site
585034006172	H-loop/switch region; other site
585034006173	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
585034006174	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034006175	dimer interface [polypeptide binding]; other site
585034006176	conserved gate region; other site
585034006177	putative PBP binding loops; other site
585034006178	ABC-ATPase subunit interface; other site
585034006179	D-cysteine desulfhydrase; Validated; Region: PRK03910
585034006180	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
585034006181	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034006182	catalytic residue [active]
585034006183	cystine transporter subunit; Provisional; Region: PRK11260
585034006184	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585034006185	substrate binding pocket [chemical binding]; other site
585034006186	membrane-bound complex binding site; other site
585034006187	hinge residues; other site
585034006188	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
585034006189	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
585034006190	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
585034006191	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
585034006192	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
585034006193	DNA binding residues [nucleotide binding]
585034006194	flagellin; Validated; Region: PRK08026
585034006195	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
585034006196	Flagellin protein; Region: FliC; pfam12445
585034006197	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
585034006198	flagellar capping protein; Reviewed; Region: fliD; PRK08032
585034006199	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
585034006200	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
585034006201	Flagellar protein FliS; Region: FliS; cl00654
585034006202	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
585034006203	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
585034006204	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
585034006205	active site
585034006206	Na/Ca binding site [ion binding]; other site
585034006207	catalytic site [active]
585034006208	lipoprotein; Provisional; Region: PRK10397
585034006209	putative inner membrane protein; Provisional; Region: PRK11099
585034006210	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
585034006211	CPxP  motif; other site
585034006212	hypothetical protein; Provisional; Region: PRK09951
585034006213	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
585034006214	flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); Region: fliF; TIGR00206
585034006215	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
585034006216	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
585034006217	flagellar motor switch protein FliG; Region: fliG; TIGR00207
585034006218	FliG C-terminal domain; Region: FliG_C; pfam01706
585034006219	flagellar assembly protein H; Validated; Region: fliH; PRK05687
585034006220	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
585034006221	Flagellar assembly protein FliH; Region: FliH; pfam02108
585034006222	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
585034006223	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
585034006224	Walker A motif/ATP binding site; other site
585034006225	Walker B motif; other site
585034006226	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
585034006227	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
585034006228	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
585034006229	flagellar hook-length control protein; Provisional; Region: PRK10118
585034006230	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
585034006231	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
585034006232	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
585034006233	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
585034006234	flagellar motor switch protein; Validated; Region: fliN; PRK05698
585034006235	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
585034006236	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
585034006237	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
585034006238	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
585034006239	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
585034006240	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585034006241	DNA binding residues [nucleotide binding]
585034006242	dimerization interface [polypeptide binding]; other site
585034006243	hypothetical protein; Provisional; Region: PRK10708
585034006244	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
585034006245	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
585034006246	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034006247	active site
585034006248	motif I; other site
585034006249	motif II; other site
585034006250	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
585034006251	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585034006252	metal binding site [ion binding]; metal-binding site
585034006253	active site
585034006254	I-site; other site
585034006255	Uncharacterized small protein (DUF2158); Region: DUF2158; cl02293
585034006256	hypothetical protein; Provisional; Region: PRK10062
585034006257	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
585034006258	EamA-like transporter family; Region: EamA; pfam00892
585034006259	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
585034006260	additional DNA contacts [nucleotide binding]; other site
585034006261	mismatch recognition site; other site
585034006262	active site
585034006263	zinc binding site [ion binding]; other site
585034006264	DNA intercalation site [nucleotide binding]; other site
585034006265	DNA cytosine methylase; Provisional; Region: PRK10458
585034006266	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
585034006267	cofactor binding site; other site
585034006268	DNA binding site [nucleotide binding]
585034006269	substrate interaction site [chemical binding]; other site
585034006270	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
585034006271	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
585034006272	Zn2+ binding site [ion binding]; other site
585034006273	Mg2+ binding site [ion binding]; other site
585034006274	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
585034006275	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
585034006276	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
585034006277	trimer interface [polypeptide binding]; other site
585034006278	eyelet of channel; other site
585034006279	chaperone protein HchA; Provisional; Region: PRK04155
585034006280	Type 1 glutamine amidotransferase (GATase1)-like domain found in Escherichia coli Hsp31 protein (EcHsp31); Region: GATase1_EcHsp31_like; cd03148
585034006281	dimer interface [polypeptide binding]; other site
585034006282	metal binding site [ion binding]; metal-binding site
585034006283	potential oxyanion hole; other site
585034006284	potential catalytic triad [active]
585034006285	conserved cys residue [active]
585034006286	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
585034006287	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585034006288	dimer interface [polypeptide binding]; other site
585034006289	phosphorylation site [posttranslational modification]
585034006290	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034006291	ATP binding site [chemical binding]; other site
585034006292	Mg2+ binding site [ion binding]; other site
585034006293	G-X-G motif; other site
585034006294	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
585034006295	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034006296	active site
585034006297	phosphorylation site [posttranslational modification]
585034006298	intermolecular recognition site; other site
585034006299	dimerization interface [polypeptide binding]; other site
585034006300	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585034006301	DNA binding site [nucleotide binding]
585034006302	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
585034006303	active site
585034006304	homotetramer interface [polypeptide binding]; other site
585034006305	TMAO/DMSO reductase; Reviewed; Region: PRK05363
585034006306	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
585034006307	Moco binding site; other site
585034006308	metal coordination site [ion binding]; other site
585034006309	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
585034006310	zinc/cadmium-binding protein; Provisional; Region: PRK10306
585034006311	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
585034006312	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
585034006313	fragment of putative invasin (part 1);Evidence 7 : Gene remnant; Product type pm : putative membrane component
585034006314	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
585034006315	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
585034006316	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
585034006317	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
585034006318	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
585034006319	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
585034006320	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
585034006321	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
585034006322	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
585034006323	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
585034006324	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
585034006325	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
585034006326	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
585034006327	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
585034006328	putative transposase OrfB; Reviewed; Region: PHA02517
585034006329	HTH-like domain; Region: HTH_21; pfam13276
585034006330	Integrase core domain; Region: rve; pfam00665
585034006331	Integrase core domain; Region: rve_2; pfam13333
585034006332	Transposase; Region: HTH_Tnp_1; cl17663
585034006333	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
585034006334	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
585034006335	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
585034006336	shikimate transporter; Provisional; Region: PRK09952
585034006337	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034006338	putative substrate translocation pore; other site
585034006339	AMP nucleosidase; Provisional; Region: PRK08292
585034006340	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
585034006341	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
585034006342	hypothetical protein; Provisional; Region: PRK12378
585034006343	MATE family multidrug exporter; Provisional; Region: PRK10189
585034006344	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
585034006345	transcriptional regulator Cbl; Reviewed; Region: cbl; PRK12679
585034006346	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034006347	The C-terminal substrate binding domain of LysR-type transcriptional regulator Cbl, which is required for expression of sulfate starvation-inducible (ssi) genes, contains the type 2 periplasmic binding fold; Region: PBP2_Cbl; cd08444
585034006348	putative substrate binding site [chemical binding]; other site
585034006349	dimerization interface [polypeptide binding]; other site
585034006350	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
585034006351	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034006352	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
585034006353	putative dimerization interface [polypeptide binding]; other site
585034006354	L,D-transpeptidase; Provisional; Region: PRK10190
585034006355	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
585034006356	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
585034006357	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
585034006358	putative dimer interface [polypeptide binding]; other site
585034006359	active site pocket [active]
585034006360	putative cataytic base [active]
585034006361	cobalamin 5'-phosphate synthase/cobalamin synthase; Region: cobS; TIGR00317
585034006362	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
585034006363	homotrimer interface [polypeptide binding]; other site
585034006364	Walker A motif; other site
585034006365	GTP binding site [chemical binding]; other site
585034006366	Walker B motif; other site
585034006367	fragment of conserved hypothetical protein, putative Cobalamin biosynthesis protein CbiG (partial);Evidence 7 : Gene remnant
585034006368	fragment of putative Propanediol utilization protein pduV a.k.a. yoeF (partial);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585034006369	hypothetical protein; Provisional; Region: PRK05423
585034006370	Predicted membrane protein [Function unknown]; Region: COG1289
585034006371	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
585034006372	DNA gyrase inhibitor; Provisional; Region: PRK10016
585034006373	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
585034006374	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
585034006375	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
585034006376	exonuclease I; Provisional; Region: sbcB; PRK11779
585034006377	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
585034006378	active site
585034006379	catalytic site [active]
585034006380	substrate binding site [chemical binding]; other site
585034006381	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
585034006382	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
585034006383	CPxP  motif; other site
585034006384	putative selenium metabolism protein, YedE family; Region: seleno_YedE; TIGR04112
585034006385	Sulphur transport; Region: Sulf_transp; pfam04143
585034006386	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
585034006387	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034006388	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
585034006389	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
585034006390	dimerization interface [polypeptide binding]; other site
585034006391	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
585034006392	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
585034006393	putative NAD(P) binding site [chemical binding]; other site
585034006394	Plasmid encoded toxin Txe; Region: Plasmid_Txe; pfam06769
585034006395	antitoxin YefM; Provisional; Region: PRK11409
585034006396	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
585034006397	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
585034006398	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
585034006399	Histidinol dehydrogenase; Region: Histidinol_dh; pfam00815
585034006400	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
585034006401	NAD binding site [chemical binding]; other site
585034006402	dimerization interface [polypeptide binding]; other site
585034006403	product binding site; other site
585034006404	substrate binding site [chemical binding]; other site
585034006405	zinc binding site [ion binding]; other site
585034006406	catalytic residues [active]
585034006407	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
585034006408	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585034006409	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034006410	homodimer interface [polypeptide binding]; other site
585034006411	catalytic residue [active]
585034006412	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
585034006413	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034006414	active site
585034006415	motif I; other site
585034006416	motif II; other site
585034006417	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
585034006418	putative active site pocket [active]
585034006419	4-fold oligomerization interface [polypeptide binding]; other site
585034006420	metal binding residues [ion binding]; metal-binding site
585034006421	3-fold/trimer interface [polypeptide binding]; other site
585034006422	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
585034006423	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
585034006424	putative active site [active]
585034006425	oxyanion strand; other site
585034006426	catalytic triad [active]
585034006427	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
585034006428	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
585034006429	catalytic residues [active]
585034006430	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
585034006431	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
585034006432	substrate binding site [chemical binding]; other site
585034006433	glutamase interaction surface [polypeptide binding]; other site
585034006434	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
585034006435	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
585034006436	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
585034006437	metal binding site [ion binding]; metal-binding site
585034006438	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
585034006439	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_4; cd03795
585034006440	putative ADP-binding pocket [chemical binding]; other site
585034006441	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
585034006442	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
585034006443	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
585034006444	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
585034006445	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
585034006446	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
585034006447	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
585034006448	This family is most closely related to the GT1 family of glycosyltransferases. ORF704 in E. coli has been shown to be involved in the biosynthesis of O-specific mannose homopolysaccharides; Region: GT1_ecORF704_like; cd03822
585034006449	Methyltransferase domain; Region: Methyltransf_23; pfam13489
585034006450	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034006451	S-adenosylmethionine binding site [chemical binding]; other site
585034006452	gliding motility-associated protein GldL; Region: GldL_gliding; TIGR03513
585034006453	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
585034006454	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
585034006455	Walker A/P-loop; other site
585034006456	ATP binding site [chemical binding]; other site
585034006457	Q-loop/lid; other site
585034006458	ABC transporter signature motif; other site
585034006459	Walker B; other site
585034006460	D-loop; other site
585034006461	H-loop/switch region; other site
585034006462	C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; Region: Wzt_C-like; cd10147
585034006463	putative carbohydrate binding site [chemical binding]; other site
585034006464	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
585034006465	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
585034006466	phosphomannomutase CpsG; Provisional; Region: PRK15414
585034006467	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
585034006468	active site
585034006469	substrate binding site [chemical binding]; other site
585034006470	metal binding site [ion binding]; metal-binding site
585034006471	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
585034006472	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
585034006473	Substrate binding site; other site
585034006474	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
585034006475	chain length determinant protein WzzB; Provisional; Region: PRK15471
585034006476	Chain length determinant protein; Region: Wzz; pfam02706
585034006477	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
585034006478	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
585034006479	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
585034006480	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
585034006481	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
585034006482	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
585034006483	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
585034006484	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
585034006485	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
585034006486	UDP-glucose 4-epimerase; Region: PLN02240
585034006487	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
585034006488	NAD binding site [chemical binding]; other site
585034006489	homodimer interface [polypeptide binding]; other site
585034006490	active site
585034006491	substrate binding site [chemical binding]; other site
585034006492	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
585034006493	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
585034006494	active site
585034006495	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
585034006496	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term; Region: FrhB_FdhB_N; pfam04422
585034006497	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus; Region: FrhB_FdhB_C; pfam04432
585034006498	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
585034006499	active site
585034006500	tetramer interface; other site
585034006501	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
585034006502	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
585034006503	putative NAD(P) binding site [chemical binding]; other site
585034006504	active site
585034006505	putative substrate binding site [chemical binding]; other site
585034006506	putative colanic acid biosynthesis protein; Provisional; Region: wcaM; PRK10123
585034006507	colanic acid biosynthesis glycosyltransferase WcaL; Region: wcaL; TIGR04005
585034006508	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
585034006509	putative ADP-binding pocket [chemical binding]; other site
585034006510	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
585034006511	colanic acid biosynthesis pyruvyl transferase WcaK; Region: wcaK; TIGR04006
585034006512	colanic acid exporter; Provisional; Region: PRK10459
585034006513	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
585034006514	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
585034006515	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
585034006516	phosphomannomutase CpsG; Provisional; Region: PRK15414
585034006517	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
585034006518	active site
585034006519	substrate binding site [chemical binding]; other site
585034006520	metal binding site [ion binding]; metal-binding site
585034006521	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
585034006522	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
585034006523	Substrate binding site; other site
585034006524	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
585034006525	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
585034006526	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
585034006527	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
585034006528	active site
585034006529	GDP-Mannose binding site [chemical binding]; other site
585034006530	dimer interface [polypeptide binding]; other site
585034006531	modified nudix motif
585034006532	metal binding site [ion binding]; metal-binding site
585034006533	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
585034006534	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
585034006535	NADP binding site [chemical binding]; other site
585034006536	active site
585034006537	putative substrate binding site [chemical binding]; other site
585034006538	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
585034006539	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
585034006540	NADP-binding site; other site
585034006541	homotetramer interface [polypeptide binding]; other site
585034006542	substrate binding site [chemical binding]; other site
585034006543	homodimer interface [polypeptide binding]; other site
585034006544	active site
585034006545	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
585034006546	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
585034006547	putative trimer interface [polypeptide binding]; other site
585034006548	putative active site [active]
585034006549	putative substrate binding site [chemical binding]; other site
585034006550	putative CoA binding site [chemical binding]; other site
585034006551	putative glycosyl transferase; Provisional; Region: PRK10063
585034006552	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
585034006553	metal-binding site
585034006554	putative colanic acid polymerase WcaD; Region: WcaD; TIGR04010
585034006555	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
585034006556	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
585034006557	putative acyl transferase; Provisional; Region: PRK10191
585034006558	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
585034006559	trimer interface [polypeptide binding]; other site
585034006560	active site
585034006561	substrate binding site [chemical binding]; other site
585034006562	CoA binding site [chemical binding]; other site
585034006563	putative glycosyl transferase; Provisional; Region: PRK10018
585034006564	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
585034006565	active site
585034006566	tyrosine kinase; Provisional; Region: PRK11519
585034006567	Chain length determinant protein; Region: Wzz; pfam02706
585034006568	Chain length determinant protein; Region: Wzz; cl15801
585034006569	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
585034006570	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
585034006571	Low molecular weight phosphatase family; Region: LMWPc; cd00115
585034006572	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
585034006573	active site
585034006574	polysaccharide export protein Wza; Provisional; Region: PRK15078
585034006575	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
585034006576	SLBB domain; Region: SLBB; pfam10531
585034006577	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
585034006578	FOG: CBS domain [General function prediction only]; Region: COG0517
585034006579	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
585034006580	Transporter associated domain; Region: CorC_HlyC; smart01091
585034006581	putative assembly protein; Provisional; Region: PRK10833
585034006582	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
585034006583	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
585034006584	trimer interface [polypeptide binding]; other site
585034006585	active site
585034006586	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
585034006587	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
585034006588	ATP-binding site [chemical binding]; other site
585034006589	Sugar specificity; other site
585034006590	Pyrimidine base specificity; other site
585034006591	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
585034006592	putative diguanylate cyclase; Provisional; Region: PRK09776
585034006593	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585034006594	putative active site [active]
585034006595	heme pocket [chemical binding]; other site
585034006596	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585034006597	putative active site [active]
585034006598	heme pocket [chemical binding]; other site
585034006599	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585034006600	putative active site [active]
585034006601	heme pocket [chemical binding]; other site
585034006602	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585034006603	metal binding site [ion binding]; metal-binding site
585034006604	active site
585034006605	I-site; other site
585034006606	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585034006607	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
585034006608	AlkA N-terminal domain; Region: AlkA_N; smart01009
585034006609	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
585034006610	minor groove reading motif; other site
585034006611	helix-hairpin-helix signature motif; other site
585034006612	substrate binding pocket [chemical binding]; other site
585034006613	active site
585034006614	putative chaperone; Provisional; Region: PRK11678
585034006615	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
585034006616	nucleotide binding site [chemical binding]; other site
585034006617	putative NEF/HSP70 interaction site [polypeptide binding]; other site
585034006618	SBD interface [polypeptide binding]; other site
585034006619	Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only]; Region: COG4248
585034006620	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
585034006621	substrate binding site [chemical binding]; other site
585034006622	activation loop (A-loop); other site
585034006623	Y-family of DNA polymerases; Region: PolY; cl12025
585034006624	Protein phosphatase 2C; Region: PP2C_2; pfam13672
585034006625	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
585034006626	metal ion-dependent adhesion site (MIDAS); other site
585034006627	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
585034006628	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585034006629	HlyD family secretion protein; Region: HlyD_3; pfam13437
585034006630	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
585034006631	Protein export membrane protein; Region: SecD_SecF; cl14618
585034006632	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
585034006633	putative transporter; Provisional; Region: PRK10504
585034006634	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034006635	putative substrate translocation pore; other site
585034006636	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034006637	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
585034006638	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585034006639	dimerization interface [polypeptide binding]; other site
585034006640	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585034006641	dimer interface [polypeptide binding]; other site
585034006642	phosphorylation site [posttranslational modification]
585034006643	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034006644	ATP binding site [chemical binding]; other site
585034006645	Mg2+ binding site [ion binding]; other site
585034006646	G-X-G motif; other site
585034006647	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
585034006648	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034006649	active site
585034006650	phosphorylation site [posttranslational modification]
585034006651	intermolecular recognition site; other site
585034006652	dimerization interface [polypeptide binding]; other site
585034006653	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585034006654	DNA binding site [nucleotide binding]
585034006655	Uncharacterized conserved protein [Function unknown]; Region: COG3422
585034006656	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
585034006657	putative addiction module antidote protein, CC2985 family; Region: antidote_CC2985; TIGR02606
585034006658	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
585034006659	putative protease; Provisional; Region: PRK15452
585034006660	Peptidase family U32; Region: Peptidase_U32; pfam01136
585034006661	lipid kinase; Reviewed; Region: PRK13054
585034006662	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
585034006663	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
585034006664	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
585034006665	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585034006666	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
585034006667	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
585034006668	putative NAD(P) binding site [chemical binding]; other site
585034006669	catalytic Zn binding site [ion binding]; other site
585034006670	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
585034006671	PTS system, galactitol-specific IIC component; Region: EIIC-GAT; TIGR00827
585034006672	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
585034006673	active site
585034006674	P-loop; other site
585034006675	phosphorylation site [posttranslational modification]
585034006676	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
585034006677	active site
585034006678	phosphorylation site [posttranslational modification]
585034006679	D-tagatose-1,6-bisphosphate aldolase subunit GatZ; Provisional; Region: PRK15052
585034006680	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
585034006681	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
585034006682	intersubunit interface [polypeptide binding]; other site
585034006683	active site
585034006684	zinc binding site [ion binding]; other site
585034006685	Na+ binding site [ion binding]; other site
585034006686	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
585034006687	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
585034006688	putative active site; other site
585034006689	catalytic residue [active]
585034006690	nucleoside transporter; Region: 2A0110; TIGR00889
585034006691	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034006692	putative substrate translocation pore; other site
585034006693	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
585034006694	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
585034006695	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
585034006696	substrate binding site [chemical binding]; other site
585034006697	ATP binding site [chemical binding]; other site
585034006698	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
585034006699	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034006700	DNA-binding site [nucleotide binding]; DNA binding site
585034006701	UTRA domain; Region: UTRA; pfam07702
585034006702	Lyzozyme M1 (1,4-beta-N-acetylmuramidase) [Cell envelope biogenesis, outer membrane]; Region: Acm; COG3757
585034006703	YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins; Region: GH25_YegX-like; cd06524
585034006704	active site
585034006705	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
585034006706	dimer interface [polypeptide binding]; other site
585034006707	substrate binding site [chemical binding]; other site
585034006708	ATP binding site [chemical binding]; other site
585034006709	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
585034006710	substrate binding site [chemical binding]; other site
585034006711	multimerization interface [polypeptide binding]; other site
585034006712	ATP binding site [chemical binding]; other site
585034006713	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
585034006714	putative metal binding site [ion binding]; other site
585034006715	putative homodimer interface [polypeptide binding]; other site
585034006716	putative homotetramer interface [polypeptide binding]; other site
585034006717	putative homodimer-homodimer interface [polypeptide binding]; other site
585034006718	putative allosteric switch controlling residues; other site
585034006719	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
585034006720	Predicted integral membrane protein [Function unknown]; Region: COG5455
585034006721	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
585034006722	putative fimbrial biosynthesis regulatory protein; Provisional; Region: PRK15216
585034006723	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
585034006724	PapC N-terminal domain; Region: PapC_N; pfam13954
585034006725	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585034006726	PapC C-terminal domain; Region: PapC_C; pfam13953
585034006727	putative fimbrial assembly chaperone protein StcB; Provisional; Region: PRK15253
585034006728	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585034006729	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
585034006730	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
585034006731	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
585034006732	antiporter inner membrane protein; Provisional; Region: PRK11670
585034006733	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
585034006734	Walker A motif; other site
585034006735	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
585034006736	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
585034006737	active site
585034006738	HIGH motif; other site
585034006739	KMSKS motif; other site
585034006740	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
585034006741	tRNA binding surface [nucleotide binding]; other site
585034006742	anticodon binding site; other site
585034006743	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
585034006744	dimer interface [polypeptide binding]; other site
585034006745	putative tRNA-binding site [nucleotide binding]; other site
585034006746	WGR domain of molybdate metabolism regulator and related proteins; Region: WGR_MMR_like; cd07996
585034006747	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
585034006748	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
585034006749	MoxR-like ATPases [General function prediction only]; Region: COG0714
585034006750	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034006751	Walker A motif; other site
585034006752	ATP binding site [chemical binding]; other site
585034006753	Walker B motif; other site
585034006754	arginine finger; other site
585034006755	VWA domain containing CoxE-like protein; Region: VWA_CoxE; pfam05762
585034006756	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
585034006757	metal ion-dependent adhesion site (MIDAS); other site
585034006758	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
585034006759	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
585034006760	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
585034006761	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
585034006762	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
585034006763	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034006764	active site
585034006765	phosphorylation site [posttranslational modification]
585034006766	intermolecular recognition site; other site
585034006767	dimerization interface [polypeptide binding]; other site
585034006768	LytTr DNA-binding domain; Region: LytTR; pfam04397
585034006769	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
585034006770	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
585034006771	GAF domain; Region: GAF; pfam01590
585034006772	Histidine kinase; Region: His_kinase; pfam06580
585034006773	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034006774	ATP binding site [chemical binding]; other site
585034006775	Mg2+ binding site [ion binding]; other site
585034006776	G-X-G motif; other site
585034006777	transcriptional regulator MirA; Provisional; Region: PRK15043
585034006778	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
585034006779	DNA binding residues [nucleotide binding]
585034006780	hypothetical protein; Provisional; Region: PRK13681
585034006781	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
585034006782	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034006783	dimer interface [polypeptide binding]; other site
585034006784	conserved gate region; other site
585034006785	putative PBP binding loops; other site
585034006786	ABC-ATPase subunit interface; other site
585034006787	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
585034006788	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
585034006789	Walker A/P-loop; other site
585034006790	ATP binding site [chemical binding]; other site
585034006791	Q-loop/lid; other site
585034006792	ABC transporter signature motif; other site
585034006793	Walker B; other site
585034006794	D-loop; other site
585034006795	H-loop/switch region; other site
585034006796	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
585034006797	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034006798	dimer interface [polypeptide binding]; other site
585034006799	conserved gate region; other site
585034006800	ABC-ATPase subunit interface; other site
585034006801	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
585034006802	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
585034006803	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
585034006804	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
585034006805	D-lactate dehydrogenase; Provisional; Region: PRK11183
585034006806	FAD binding domain; Region: FAD_binding_4; pfam01565
585034006807	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
585034006808	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
585034006809	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
585034006810	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
585034006811	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
585034006812	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
585034006813	oxidoreductase; Provisional; Region: PRK12743
585034006814	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
585034006815	NAD(P) binding site [chemical binding]; other site
585034006816	active site
585034006817	Outer membrane efflux protein; Region: OEP; pfam02321
585034006818	Outer membrane efflux protein; Region: OEP; pfam02321
585034006819	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
585034006820	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
585034006821	FMN binding site [chemical binding]; other site
585034006822	active site
585034006823	catalytic residues [active]
585034006824	substrate binding site [chemical binding]; other site
585034006825	hypothetical protein; Provisional; Region: PRK01821
585034006826	hypothetical protein; Provisional; Region: PRK10711
585034006827	cytidine deaminase; Provisional; Region: PRK09027
585034006828	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
585034006829	active site
585034006830	catalytic motif [active]
585034006831	Zn binding site [ion binding]; other site
585034006832	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
585034006833	active site
585034006834	catalytic motif [active]
585034006835	Zn binding site [ion binding]; other site
585034006836	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
585034006837	putative active site [active]
585034006838	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
585034006839	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
585034006840	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
585034006841	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585034006842	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
585034006843	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
585034006844	homodimer interface [polypeptide binding]; other site
585034006845	active site
585034006846	FMN binding site [chemical binding]; other site
585034006847	substrate binding site [chemical binding]; other site
585034006848	4Fe-4S binding domain; Region: Fer4; pfam00037
585034006849	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585034006850	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585034006851	TM-ABC transporter signature motif; other site
585034006852	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
585034006853	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
585034006854	Walker A/P-loop; other site
585034006855	ATP binding site [chemical binding]; other site
585034006856	Q-loop/lid; other site
585034006857	ABC transporter signature motif; other site
585034006858	Walker B; other site
585034006859	D-loop; other site
585034006860	H-loop/switch region; other site
585034006861	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
585034006862	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
585034006863	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
585034006864	ligand binding site [chemical binding]; other site
585034006865	calcium binding site [ion binding]; other site
585034006866	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
585034006867	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585034006868	DNA binding site [nucleotide binding]
585034006869	domain linker motif; other site
585034006870	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
585034006871	dimerization interface (closed form) [polypeptide binding]; other site
585034006872	ligand binding site [chemical binding]; other site
585034006873	Predicted membrane protein [Function unknown]; Region: COG2311
585034006874	hypothetical protein; Provisional; Region: PRK10835
585034006875	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
585034006876	homodecamer interface [polypeptide binding]; other site
585034006877	GTP cyclohydrolase I; Provisional; Region: PLN03044
585034006878	active site
585034006879	putative catalytic site residues [active]
585034006880	zinc binding site [ion binding]; other site
585034006881	GTP-CH-I/GFRP interaction surface; other site
585034006882	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
585034006883	S-formylglutathione hydrolase; Region: PLN02442
585034006884	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
585034006885	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585034006886	N-terminal plug; other site
585034006887	ligand-binding site [chemical binding]; other site
585034006888	lysine transporter; Provisional; Region: PRK10836
585034006889	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
585034006890	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034006891	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
585034006892	putative dimerization interface [polypeptide binding]; other site
585034006893	conserved hypothetical integral membrane protein; Region: TIGR00698
585034006894	endonuclease IV; Provisional; Region: PRK01060
585034006895	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
585034006896	AP (apurinic/apyrimidinic) site pocket; other site
585034006897	DNA interaction; other site
585034006898	Metal-binding active site; metal-binding site
585034006899	putative kinase; Provisional; Region: PRK09954
585034006900	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
585034006901	putative DNA binding site [nucleotide binding]; other site
585034006902	putative Zn2+ binding site [ion binding]; other site
585034006903	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
585034006904	substrate binding site [chemical binding]; other site
585034006905	ATP binding site [chemical binding]; other site
585034006906	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
585034006907	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
585034006908	Nucleoside recognition; Region: Gate; pfam07670
585034006909	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
585034006910	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
585034006911	active site
585034006912	tetramer interface [polypeptide binding]; other site
585034006913	DNA-binding transcriptional activator YeiL; Provisional; Region: PRK10402
585034006914	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
585034006915	ligand binding site [chemical binding]; other site
585034006916	flexible hinge region; other site
585034006917	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
585034006918	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
585034006919	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
585034006920	Nucleoside recognition; Region: Gate; pfam07670
585034006921	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
585034006922	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
585034006923	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
585034006924	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
585034006925	substrate binding site [chemical binding]; other site
585034006926	ATP binding site [chemical binding]; other site
585034006927	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
585034006928	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
585034006929	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
585034006930	active site
585034006931	P-loop; other site
585034006932	phosphorylation site [posttranslational modification]
585034006933	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
585034006934	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
585034006935	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
585034006936	putative substrate binding site [chemical binding]; other site
585034006937	putative ATP binding site [chemical binding]; other site
585034006938	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
585034006939	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
585034006940	active site
585034006941	phosphorylation site [posttranslational modification]
585034006942	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
585034006943	dimerization domain swap beta strand [polypeptide binding]; other site
585034006944	regulatory protein interface [polypeptide binding]; other site
585034006945	active site
585034006946	regulatory phosphorylation site [posttranslational modification]; other site
585034006947	sugar efflux transporter B; Provisional; Region: PRK15011
585034006948	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034006949	putative substrate translocation pore; other site
585034006950	Flagellin N-methylase; Region: FliB; pfam03692
585034006951	elongation factor P; Provisional; Region: PRK04542
585034006952	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
585034006953	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
585034006954	RNA binding site [nucleotide binding]; other site
585034006955	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
585034006956	RNA binding site [nucleotide binding]; other site
585034006957	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
585034006958	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
585034006959	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
585034006960	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
585034006961	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
585034006962	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
585034006963	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
585034006964	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
585034006965	active site
585034006966	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
585034006967	NlpC/P60 family; Region: NLPC_P60; pfam00877
585034006968	phage resistance protein; Provisional; Region: PRK10551
585034006969	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
585034006970	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585034006971	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
585034006972	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
585034006973	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
585034006974	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034006975	dimer interface [polypeptide binding]; other site
585034006976	conserved gate region; other site
585034006977	putative PBP binding loops; other site
585034006978	ABC-ATPase subunit interface; other site
585034006979	microcin C ABC transporter permease; Provisional; Region: PRK15021
585034006980	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034006981	dimer interface [polypeptide binding]; other site
585034006982	conserved gate region; other site
585034006983	ABC-ATPase subunit interface; other site
585034006984	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
585034006985	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585034006986	Walker A/P-loop; other site
585034006987	ATP binding site [chemical binding]; other site
585034006988	Q-loop/lid; other site
585034006989	ABC transporter signature motif; other site
585034006990	Walker B; other site
585034006991	D-loop; other site
585034006992	H-loop/switch region; other site
585034006993	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
585034006994	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585034006995	Walker A/P-loop; other site
585034006996	ATP binding site [chemical binding]; other site
585034006997	Q-loop/lid; other site
585034006998	ABC transporter signature motif; other site
585034006999	Walker B; other site
585034007000	D-loop; other site
585034007001	H-loop/switch region; other site
585034007002	hypothetical protein; Provisional; Region: PRK11835
585034007003	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034007004	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
585034007005	putative substrate translocation pore; other site
585034007006	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
585034007007	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
585034007008	RNA binding surface [nucleotide binding]; other site
585034007009	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
585034007010	active site
585034007011	uracil binding [chemical binding]; other site
585034007012	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
585034007013	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585034007014	ATP binding site [chemical binding]; other site
585034007015	putative Mg++ binding site [ion binding]; other site
585034007016	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585034007017	nucleotide binding region [chemical binding]; other site
585034007018	ATP-binding site [chemical binding]; other site
585034007019	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
585034007020	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
585034007021	5S rRNA interface [nucleotide binding]; other site
585034007022	CTC domain interface [polypeptide binding]; other site
585034007023	L16 interface [polypeptide binding]; other site
585034007024	Nucleoid-associated protein [General function prediction only]; Region: COG3081
585034007025	nucleoid-associated protein NdpA; Validated; Region: PRK00378
585034007026	hypothetical protein; Provisional; Region: PRK13689
585034007027	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
585034007028	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
585034007029	Sulfatase; Region: Sulfatase; pfam00884
585034007030	fragment of putative autotransporter outer membrane protein; type V secretion (part 2);Evidence 7 : Gene remnant; Product type pt : putative transporter
585034007031	fragment of putative autotransporter outer membrane protein; type V secretion (part 1);Evidence 7 : Gene remnant; Product type pt : putative transporter
585034007032	transcriptional regulator NarP; Provisional; Region: PRK10403
585034007033	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034007034	active site
585034007035	phosphorylation site [posttranslational modification]
585034007036	intermolecular recognition site; other site
585034007037	dimerization interface [polypeptide binding]; other site
585034007038	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585034007039	DNA binding residues [nucleotide binding]
585034007040	dimerization interface [polypeptide binding]; other site
585034007041	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
585034007042	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
585034007043	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585034007044	binding surface
585034007045	TPR motif; other site
585034007046	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
585034007047	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
585034007048	catalytic residues [active]
585034007049	central insert; other site
585034007050	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
585034007051	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13165
585034007052	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
585034007053	heme exporter protein CcmC; Region: ccmC; TIGR01191
585034007054	heme exporter protein CcmB; Region: ccmB; TIGR01190
585034007055	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
585034007056	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
585034007057	Walker A/P-loop; other site
585034007058	ATP binding site [chemical binding]; other site
585034007059	Q-loop/lid; other site
585034007060	ABC transporter signature motif; other site
585034007061	Walker B; other site
585034007062	D-loop; other site
585034007063	H-loop/switch region; other site
585034007064	cytochrome c-type protein NapC; Provisional; Region: PRK10617
585034007065	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
585034007066	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
585034007067	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
585034007068	4Fe-4S binding domain; Region: Fer4_5; pfam12801
585034007069	4Fe-4S binding domain; Region: Fer4_6; pfam12837
585034007070	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
585034007071	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
585034007072	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
585034007073	[4Fe-4S] binding site [ion binding]; other site
585034007074	molybdopterin cofactor binding site; other site
585034007075	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
585034007076	molybdopterin cofactor binding site; other site
585034007077	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
585034007078	ferredoxin-type protein; Provisional; Region: PRK10194
585034007079	tRNA synthetases class I (R); Region: tRNA-synt_1d; pfam00750
585034007080	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
585034007081	secondary substrate binding site; other site
585034007082	primary substrate binding site; other site
585034007083	inhibition loop; other site
585034007084	dimerization interface [polypeptide binding]; other site
585034007085	malate:quinone oxidoreductase; Validated; Region: PRK05257
585034007086	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
585034007087	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
585034007088	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
585034007089	Walker A/P-loop; other site
585034007090	ATP binding site [chemical binding]; other site
585034007091	Q-loop/lid; other site
585034007092	ABC transporter signature motif; other site
585034007093	Walker B; other site
585034007094	D-loop; other site
585034007095	H-loop/switch region; other site
585034007096	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
585034007097	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
585034007098	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
585034007099	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034007100	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034007101	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
585034007102	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
585034007103	DNA binding site [nucleotide binding]
585034007104	active site
585034007105	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
585034007106	ApbE family; Region: ApbE; pfam02424
585034007107	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
585034007108	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
585034007109	trimer interface [polypeptide binding]; other site
585034007110	eyelet of channel; other site
585034007111	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
585034007112	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034007113	ATP binding site [chemical binding]; other site
585034007114	G-X-G motif; other site
585034007115	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
585034007116	putative binding surface; other site
585034007117	active site
585034007118	transcriptional regulator RcsB; Provisional; Region: PRK10840
585034007119	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034007120	active site
585034007121	phosphorylation site [posttranslational modification]
585034007122	intermolecular recognition site; other site
585034007123	dimerization interface [polypeptide binding]; other site
585034007124	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585034007125	DNA binding residues [nucleotide binding]
585034007126	dimerization interface [polypeptide binding]; other site
585034007127	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
585034007128	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585034007129	dimer interface [polypeptide binding]; other site
585034007130	phosphorylation site [posttranslational modification]
585034007131	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034007132	ATP binding site [chemical binding]; other site
585034007133	Mg2+ binding site [ion binding]; other site
585034007134	G-X-G motif; other site
585034007135	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
585034007136	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034007137	active site
585034007138	phosphorylation site [posttranslational modification]
585034007139	intermolecular recognition site; other site
585034007140	dimerization interface [polypeptide binding]; other site
585034007141	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4676
585034007142	Uncharacterized protein conserved in bacteria (DUF2135); Region: DUF2135; pfam09906
585034007143	Predicted secreted protein [Function unknown]; Region: COG5445
585034007144	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
585034007145	Predicted secreted protein [Function unknown]; Region: COG5445
585034007146	Stage II sporulation protein; Region: SpoIID; pfam08486
585034007147	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
585034007148	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
585034007149	MG2 domain; Region: A2M_N; pfam01835
585034007150	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cl17457
585034007151	Alpha-2-macroglobulin family; Region: A2M; pfam00207
585034007152	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267
585034007153	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3234
585034007154	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4685
585034007155	DNA gyrase subunit A; Validated; Region: PRK05560
585034007156	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
585034007157	CAP-like domain; other site
585034007158	active site
585034007159	primary dimer interface [polypeptide binding]; other site
585034007160	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
585034007161	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
585034007162	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
585034007163	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
585034007164	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
585034007165	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
585034007166	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
585034007167	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034007168	S-adenosylmethionine binding site [chemical binding]; other site
585034007169	adhesin; Provisional; Region: PRK09752
585034007170	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
585034007171	Autotransporter beta-domain; Region: Autotransporter; pfam03797
585034007172	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
585034007173	ATP cone domain; Region: ATP-cone; pfam03477
585034007174	Class I ribonucleotide reductase; Region: RNR_I; cd01679
585034007175	active site
585034007176	dimer interface [polypeptide binding]; other site
585034007177	catalytic residues [active]
585034007178	effector binding site; other site
585034007179	R2 peptide binding site; other site
585034007180	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
585034007181	dimer interface [polypeptide binding]; other site
585034007182	putative radical transfer pathway; other site
585034007183	diiron center [ion binding]; other site
585034007184	tyrosyl radical; other site
585034007185	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
585034007186	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
585034007187	catalytic loop [active]
585034007188	iron binding site [ion binding]; other site
585034007189	hypothetical protein; Provisional; Region: PRK09902
585034007190	hypothetical protein; Provisional; Region: PRK09729
585034007191	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
585034007192	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
585034007193	active site
585034007194	catalytic site [active]
585034007195	metal binding site [ion binding]; metal-binding site
585034007196	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
585034007197	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034007198	putative substrate translocation pore; other site
585034007199	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
585034007200	hydroxyglutarate oxidase; Provisional; Region: PRK11728
585034007201	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
585034007202	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
585034007203	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
585034007204	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
585034007205	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
585034007206	Cysteine-rich domain; Region: CCG; pfam02754
585034007207	Cysteine-rich domain; Region: CCG; pfam02754
585034007208	hypothetical protein; Provisional; Region: PRK09956
585034007209	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
585034007210	fragment of putative 2,4-dihydroxyhept-2-ene-1, 7-dioic acid-like aldolase (partial);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585034007211	hypothetical protein; Provisional; Region: PRK03673
585034007212	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
585034007213	putative MPT binding site; other site
585034007214	Competence-damaged protein; Region: CinA; cl00666
585034007215	YfaZ precursor; Region: YfaZ; pfam07437
585034007216	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
585034007217	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
585034007218	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
585034007219	catalytic core [active]
585034007220	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
585034007221	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
585034007222	inhibitor-cofactor binding pocket; inhibition site
585034007223	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034007224	catalytic residue [active]
585034007225	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
585034007226	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
585034007227	Ligand binding site; other site
585034007228	Putative Catalytic site; other site
585034007229	DXD motif; other site
585034007230	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
585034007231	ArnA, N-terminal formyltransferase domain; Region: FMT_core_ArnA_N; cd08644
585034007232	substrate binding site [chemical binding]; other site
585034007233	cosubstrate binding site; other site
585034007234	catalytic site [active]
585034007235	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
585034007236	active site
585034007237	hexamer interface [polypeptide binding]; other site
585034007238	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
585034007239	NAD binding site [chemical binding]; other site
585034007240	substrate binding site [chemical binding]; other site
585034007241	active site
585034007242	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
585034007243	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
585034007244	putative active site [active]
585034007245	putative catalytic site [active]
585034007246	putative Zn binding site [ion binding]; other site
585034007247	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
585034007248	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
585034007249	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
585034007250	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
585034007251	signal transduction protein PmrD; Provisional; Region: PRK15450
585034007252	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
585034007253	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
585034007254	acyl-activating enzyme (AAE) consensus motif; other site
585034007255	putative AMP binding site [chemical binding]; other site
585034007256	putative active site [active]
585034007257	putative CoA binding site [chemical binding]; other site
585034007258	O-succinylbenzoate synthase; Provisional; Region: PRK05105
585034007259	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
585034007260	active site
585034007261	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
585034007262	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
585034007263	substrate binding site [chemical binding]; other site
585034007264	oxyanion hole (OAH) forming residues; other site
585034007265	trimer interface [polypeptide binding]; other site
585034007266	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
585034007267	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
585034007268	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
585034007269	dimer interface [polypeptide binding]; other site
585034007270	tetramer interface [polypeptide binding]; other site
585034007271	PYR/PP interface [polypeptide binding]; other site
585034007272	TPP binding site [chemical binding]; other site
585034007273	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
585034007274	TPP-binding site; other site
585034007275	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
585034007276	isochorismate synthases; Region: isochor_syn; TIGR00543
585034007277	hypothetical protein; Provisional; Region: PRK10404
585034007278	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585034007279	Coenzyme A binding pocket [chemical binding]; other site
585034007280	ribonuclease BN; Region: true_RNase_BN; TIGR02649
585034007281	deubiquitinase; Provisional; Region: PRK11836
585034007282	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
585034007283	Domain of unknown function (DUF1877); Region: DUF1877; pfam08974
585034007284	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
585034007285	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
585034007286	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
585034007287	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
585034007288	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
585034007289	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
585034007290	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
585034007291	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
585034007292	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
585034007293	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
585034007294	4Fe-4S binding domain; Region: Fer4; pfam00037
585034007295	4Fe-4S binding domain; Region: Fer4; pfam00037
585034007296	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
585034007297	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
585034007298	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
585034007299	catalytic loop [active]
585034007300	iron binding site [ion binding]; other site
585034007301	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
585034007302	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
585034007303	[4Fe-4S] binding site [ion binding]; other site
585034007304	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
585034007305	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
585034007306	SLBB domain; Region: SLBB; pfam10531
585034007307	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
585034007308	NADH dehydrogenase subunit E; Validated; Region: PRK07539
585034007309	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
585034007310	putative dimer interface [polypeptide binding]; other site
585034007311	[2Fe-2S] cluster binding site [ion binding]; other site
585034007312	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
585034007313	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
585034007314	NADH dehydrogenase subunit D; Validated; Region: PRK06075
585034007315	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
585034007316	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
585034007317	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
585034007318	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034007319	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
585034007320	putative dimerization interface [polypeptide binding]; other site
585034007321	aminotransferase AlaT; Validated; Region: PRK09265
585034007322	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585034007323	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034007324	homodimer interface [polypeptide binding]; other site
585034007325	catalytic residue [active]
585034007326	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
585034007327	Zn2+ binding site [ion binding]; other site
585034007328	Mg2+ binding site [ion binding]; other site
585034007329	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
585034007330	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
585034007331	TrkA-C domain; Region: TrkA_C; pfam02080
585034007332	TrkA-C domain; Region: TrkA_C; pfam02080
585034007333	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
585034007334	putative phosphatase; Provisional; Region: PRK11587
585034007335	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034007336	motif II; other site
585034007337	hypothetical protein; Validated; Region: PRK05445
585034007338	hypothetical protein; Provisional; Region: PRK01816
585034007339	propionate/acetate kinase; Provisional; Region: PRK12379
585034007340	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
585034007341	phosphate acetyltransferase; Reviewed; Region: PRK05632
585034007342	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
585034007343	DRTGG domain; Region: DRTGG; pfam07085
585034007344	phosphate acetyltransferase; Region: pta; TIGR00651
585034007345	fragment of conserved hypothetical protein; putative inner membrane protein (part 1);Evidence 7 : Gene remnant; Product type pc : putative carrier
585034007346	fragment of conserved hypothetical protein; putative inner membrane protein (part 2);Evidence 7 : Gene remnant; Product type pc : putative carrier
585034007347	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
585034007348	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
585034007349	nudix motif; other site
585034007350	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
585034007351	active site
585034007352	metal binding site [ion binding]; metal-binding site
585034007353	homotetramer interface [polypeptide binding]; other site
585034007354	glutathione S-transferase; Provisional; Region: PRK15113
585034007355	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
585034007356	C-terminal domain interface [polypeptide binding]; other site
585034007357	GSH binding site (G-site) [chemical binding]; other site
585034007358	dimer interface [polypeptide binding]; other site
585034007359	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
585034007360	N-terminal domain interface [polypeptide binding]; other site
585034007361	putative dimer interface [polypeptide binding]; other site
585034007362	putative substrate binding pocket (H-site) [chemical binding]; other site
585034007363	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
585034007364	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
585034007365	C-terminal domain interface [polypeptide binding]; other site
585034007366	GSH binding site (G-site) [chemical binding]; other site
585034007367	dimer interface [polypeptide binding]; other site
585034007368	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
585034007369	N-terminal domain interface [polypeptide binding]; other site
585034007370	putative dimer interface [polypeptide binding]; other site
585034007371	active site
585034007372	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
585034007373	homooctamer interface [polypeptide binding]; other site
585034007374	active site
585034007375	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
585034007376	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
585034007377	putative NAD(P) binding site [chemical binding]; other site
585034007378	putative active site [active]
585034007379	putative transposase; Provisional; Region: PRK09857
585034007380	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
585034007381	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
585034007382	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
585034007383	Walker A/P-loop; other site
585034007384	ATP binding site [chemical binding]; other site
585034007385	Q-loop/lid; other site
585034007386	ABC transporter signature motif; other site
585034007387	Walker B; other site
585034007388	D-loop; other site
585034007389	H-loop/switch region; other site
585034007390	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034007391	dimer interface [polypeptide binding]; other site
585034007392	conserved gate region; other site
585034007393	putative PBP binding loops; other site
585034007394	ABC-ATPase subunit interface; other site
585034007395	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
585034007396	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034007397	dimer interface [polypeptide binding]; other site
585034007398	conserved gate region; other site
585034007399	putative PBP binding loops; other site
585034007400	ABC-ATPase subunit interface; other site
585034007401	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
585034007402	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585034007403	substrate binding pocket [chemical binding]; other site
585034007404	membrane-bound complex binding site; other site
585034007405	hinge residues; other site
585034007406	fragment of lysine/arginine/ornithine transporter subunit ; periplasmic-binding component of ABC superfamily (part 2);Evidence 7 : Gene remnant; Product type t : transporter
585034007407	fragment of lysine/arginine/ornithine transporter subunit ; periplasmic-binding component of ABC superfamily (part 1);Evidence 7 : Gene remnant; Product type t : transporter
585034007408	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
585034007409	Flavoprotein; Region: Flavoprotein; pfam02441
585034007410	amidophosphoribosyltransferase; Provisional; Region: PRK09246
585034007411	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
585034007412	active site
585034007413	tetramer interface [polypeptide binding]; other site
585034007414	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
585034007415	active site
585034007416	colicin V production protein; Provisional; Region: PRK10845
585034007417	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
585034007418	cell division protein DedD; Provisional; Region: PRK11633
585034007419	Sporulation related domain; Region: SPOR; pfam05036
585034007420	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
585034007421	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
585034007422	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
585034007423	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
585034007424	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
585034007425	hypothetical protein; Provisional; Region: PRK10847
585034007426	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
585034007427	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
585034007428	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
585034007429	dimerization interface 3.5A [polypeptide binding]; other site
585034007430	active site
585034007431	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
585034007432	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
585034007433	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
585034007434	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
585034007435	ligand binding site [chemical binding]; other site
585034007436	NAD binding site [chemical binding]; other site
585034007437	catalytic site [active]
585034007438	homodimer interface [polypeptide binding]; other site
585034007439	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
585034007440	putative transporter; Provisional; Region: PRK12382
585034007441	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034007442	putative substrate translocation pore; other site
585034007443	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
585034007444	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
585034007445	dimer interface [polypeptide binding]; other site
585034007446	active site
585034007447	Uncharacterized conserved protein [Function unknown]; Region: COG4121
585034007448	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
585034007449	YfcL protein; Region: YfcL; pfam08891
585034007450	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
585034007451	hypothetical protein; Provisional; Region: PRK10621
585034007452	Predicted permeases [General function prediction only]; Region: COG0730
585034007453	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
585034007454	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
585034007455	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
585034007456	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
585034007457	Tetramer interface [polypeptide binding]; other site
585034007458	active site
585034007459	FMN-binding site [chemical binding]; other site
585034007460	HemK family putative methylases; Region: hemK_fam; TIGR00536
585034007461	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034007462	S-adenosylmethionine binding site [chemical binding]; other site
585034007463	hypothetical protein; Provisional; Region: PRK04946
585034007464	Smr domain; Region: Smr; pfam01713
585034007465	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
585034007466	Transposase; Region: DEDD_Tnp_IS110; pfam01548
585034007467	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
585034007468	Protein of unknown function (DUF2544); Region: DUF2544; pfam11245
585034007469	Fimbrial protein; Region: Fimbrial; cl01416
585034007470	Fimbrial protein; Region: Fimbrial; cl01416
585034007471	Fimbrial protein; Region: Fimbrial; cl01416
585034007472	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585034007473	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
585034007474	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
585034007475	PapC N-terminal domain; Region: PapC_N; pfam13954
585034007476	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585034007477	PapC C-terminal domain; Region: PapC_C; pfam13953
585034007478	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
585034007479	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
585034007480	catalytic core [active]
585034007481	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
585034007482	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
585034007483	substrate binding site [chemical binding]; other site
585034007484	oxyanion hole (OAH) forming residues; other site
585034007485	trimer interface [polypeptide binding]; other site
585034007486	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
585034007487	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
585034007488	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
585034007489	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
585034007490	dimer interface [polypeptide binding]; other site
585034007491	active site
585034007492	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
585034007493	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
585034007494	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
585034007495	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
585034007496	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
585034007497	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034007498	putative substrate translocation pore; other site
585034007499	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
585034007500	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
585034007501	putative substrate binding site [chemical binding]; other site
585034007502	putative ATP binding site [chemical binding]; other site
585034007503	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
585034007504	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
585034007505	substrate binding [chemical binding]; other site
585034007506	active site
585034007507	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
585034007508	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585034007509	DNA binding site [nucleotide binding]
585034007510	domain linker motif; other site
585034007511	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
585034007512	Ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_sucrose_transcription_regulator; cd06288
585034007513	putative dimerization interface [polypeptide binding]; other site
585034007514	putative ligand binding site [chemical binding]; other site
585034007515	Evidence 7 : Gene remnant; Product type pt : putative transporter; fragment of putative transporter (partial)
585034007516	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
585034007517	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
585034007518	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
585034007519	catalytic residue [active]
585034007520	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
585034007521	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034007522	putative substrate translocation pore; other site
585034007523	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034007524	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
585034007525	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585034007526	HlyD family secretion protein; Region: HlyD_3; pfam13437
585034007527	DNA-binding transcriptional activator EvgA; Provisional; Region: PRK09958
585034007528	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034007529	active site
585034007530	phosphorylation site [posttranslational modification]
585034007531	intermolecular recognition site; other site
585034007532	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585034007533	DNA binding residues [nucleotide binding]
585034007534	dimerization interface [polypeptide binding]; other site
585034007535	hybrid sensory histidine kinase in two-component regulatory system with EvgA; Provisional; Region: PRK09959
585034007536	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585034007537	substrate binding pocket [chemical binding]; other site
585034007538	membrane-bound complex binding site; other site
585034007539	hinge residues; other site
585034007540	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585034007541	substrate binding pocket [chemical binding]; other site
585034007542	membrane-bound complex binding site; other site
585034007543	hinge residues; other site
585034007544	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585034007545	dimer interface [polypeptide binding]; other site
585034007546	phosphorylation site [posttranslational modification]
585034007547	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034007548	ATP binding site [chemical binding]; other site
585034007549	Mg2+ binding site [ion binding]; other site
585034007550	G-X-G motif; other site
585034007551	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034007552	active site
585034007553	phosphorylation site [posttranslational modification]
585034007554	intermolecular recognition site; other site
585034007555	dimerization interface [polypeptide binding]; other site
585034007556	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
585034007557	putative binding surface; other site
585034007558	active site
585034007559	putative CoA-transferase; Provisional; Region: PRK11430
585034007560	CoA-transferase family III; Region: CoA_transf_3; pfam02515
585034007561	putative transporter YfdV; Provisional; Region: PRK09903
585034007562	putative oxalyl-CoA decarboxylase; Validated; Region: PRK09259
585034007563	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
585034007564	PYR/PP interface [polypeptide binding]; other site
585034007565	dimer interface [polypeptide binding]; other site
585034007566	TPP binding site [chemical binding]; other site
585034007567	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
585034007568	Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL...; Region: TPP_BZL_OCoD_HPCL; cd02004
585034007569	TPP-binding site; other site
585034007570	dimer interface [polypeptide binding]; other site
585034007571	formyl-coenzyme A transferase; Provisional; Region: PRK05398
585034007572	CoA-transferase family III; Region: CoA_transf_3; pfam02515
585034007573	hypothetical protein; Provisional; Region: PRK10316
585034007574	YfdX protein; Region: YfdX; pfam10938
585034007575	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
585034007576	similar to hypothetical protein; Evidence 4 : Homologs of previously reported genes of unknown function
585034007577	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
585034007578	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
585034007579	putative acyl-acceptor binding pocket; other site
585034007580	aminotransferase; Validated; Region: PRK08175
585034007581	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585034007582	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034007583	homodimer interface [polypeptide binding]; other site
585034007584	catalytic residue [active]
585034007585	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
585034007586	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
585034007587	GAF domain; Region: GAF; pfam01590
585034007588	Histidine kinase; Region: His_kinase; pfam06580
585034007589	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034007590	ATP binding site [chemical binding]; other site
585034007591	Mg2+ binding site [ion binding]; other site
585034007592	G-X-G motif; other site
585034007593	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
585034007594	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034007595	active site
585034007596	phosphorylation site [posttranslational modification]
585034007597	intermolecular recognition site; other site
585034007598	dimerization interface [polypeptide binding]; other site
585034007599	LytTr DNA-binding domain; Region: LytTR; pfam04397
585034007600	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
585034007601	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034007602	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
585034007603	dimerization domain swap beta strand [polypeptide binding]; other site
585034007604	regulatory protein interface [polypeptide binding]; other site
585034007605	active site
585034007606	regulatory phosphorylation site [posttranslational modification]; other site
585034007607	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
585034007608	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
585034007609	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
585034007610	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
585034007611	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
585034007612	active site
585034007613	phosphorylation site [posttranslational modification]
585034007614	exoaminopeptidase; Provisional; Region: PRK09961
585034007615	M42 Peptidases, also known as glutamyl aminopeptidase family; Region: M42; cd05638
585034007616	oligomer interface [polypeptide binding]; other site
585034007617	active site
585034007618	metal binding site [ion binding]; metal-binding site
585034007619	aminopeptidase; Provisional; Region: PRK09795
585034007620	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
585034007621	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
585034007622	active site
585034007623	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
585034007624	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
585034007625	active site
585034007626	P-loop; other site
585034007627	phosphorylation site [posttranslational modification]
585034007628	glucokinase, proteobacterial type; Region: glk; TIGR00749
585034007629	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
585034007630	nucleotide binding site [chemical binding]; other site
585034007631	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
585034007632	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
585034007633	Cl- selectivity filter; other site
585034007634	Cl- binding residues [ion binding]; other site
585034007635	pore gating glutamate residue; other site
585034007636	dimer interface [polypeptide binding]; other site
585034007637	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
585034007638	manganese transport protein MntH; Reviewed; Region: PRK00701
585034007639	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
585034007640	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
585034007641	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
585034007642	Nucleoside recognition; Region: Gate; pfam07670
585034007643	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
585034007644	MASE1; Region: MASE1; pfam05231
585034007645	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
585034007646	diguanylate cyclase; Region: GGDEF; smart00267
585034007647	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585034007648	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
585034007649	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585034007650	salt bridge; other site
585034007651	non-specific DNA binding site [nucleotide binding]; other site
585034007652	sequence-specific DNA binding site [nucleotide binding]; other site
585034007653	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
585034007654	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
585034007655	active site
585034007656	HIGH motif; other site
585034007657	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
585034007658	active site
585034007659	KMSKS motif; other site
585034007660	Transcriptional regulator [Transcription]; Region: LysR; COG0583
585034007661	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034007662	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
585034007663	putative dimerization interface [polypeptide binding]; other site
585034007664	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
585034007665	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
585034007666	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
585034007667	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
585034007668	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
585034007669	nucleotide binding pocket [chemical binding]; other site
585034007670	K-X-D-G motif; other site
585034007671	catalytic site [active]
585034007672	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
585034007673	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
585034007674	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
585034007675	Dimer interface [polypeptide binding]; other site
585034007676	BRCT sequence motif; other site
585034007677	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
585034007678	cell division protein ZipA; Provisional; Region: PRK03427
585034007679	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
585034007680	FtsZ protein binding site [polypeptide binding]; other site
585034007681	putative sulfate transport protein CysZ; Validated; Region: PRK04949
585034007682	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
585034007683	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
585034007684	dimer interface [polypeptide binding]; other site
585034007685	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034007686	catalytic residue [active]
585034007687	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
585034007688	dimerization domain swap beta strand [polypeptide binding]; other site
585034007689	regulatory protein interface [polypeptide binding]; other site
585034007690	active site
585034007691	regulatory phosphorylation site [posttranslational modification]; other site
585034007692	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
585034007693	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
585034007694	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
585034007695	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
585034007696	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
585034007697	HPr interaction site; other site
585034007698	glycerol kinase (GK) interaction site [polypeptide binding]; other site
585034007699	active site
585034007700	phosphorylation site [posttranslational modification]
585034007701	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
585034007702	dimer interface [polypeptide binding]; other site
585034007703	pyridoxamine kinase; Validated; Region: PRK05756
585034007704	pyridoxal binding site [chemical binding]; other site
585034007705	ATP binding site [chemical binding]; other site
585034007706	hypothetical protein; Provisional; Region: PRK10318
585034007707	cysteine synthase B; Region: cysM; TIGR01138
585034007708	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
585034007709	dimer interface [polypeptide binding]; other site
585034007710	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034007711	catalytic residue [active]
585034007712	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
585034007713	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
585034007714	Walker A/P-loop; other site
585034007715	ATP binding site [chemical binding]; other site
585034007716	Q-loop/lid; other site
585034007717	ABC transporter signature motif; other site
585034007718	Walker B; other site
585034007719	D-loop; other site
585034007720	H-loop/switch region; other site
585034007721	TOBE-like domain; Region: TOBE_3; pfam12857
585034007722	sulfate transport protein; Provisional; Region: cysT; CHL00187
585034007723	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034007724	dimer interface [polypeptide binding]; other site
585034007725	conserved gate region; other site
585034007726	putative PBP binding loops; other site
585034007727	ABC-ATPase subunit interface; other site
585034007728	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
585034007729	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034007730	dimer interface [polypeptide binding]; other site
585034007731	conserved gate region; other site
585034007732	putative PBP binding loops; other site
585034007733	ABC-ATPase subunit interface; other site
585034007734	thiosulfate transporter subunit; Provisional; Region: PRK10852
585034007735	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
585034007736	short chain dehydrogenase; Provisional; Region: PRK08226
585034007737	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
585034007738	NAD binding site [chemical binding]; other site
585034007739	homotetramer interface [polypeptide binding]; other site
585034007740	homodimer interface [polypeptide binding]; other site
585034007741	active site
585034007742	transcriptional regulator MurR; Provisional; Region: PRK15482
585034007743	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
585034007744	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
585034007745	putative active site [active]
585034007746	N-acetylmuramic acid 6-phosphate etherase; Region: TIGR00274
585034007747	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
585034007748	putative active site [active]
585034007749	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
585034007750	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
585034007751	active site turn [active]
585034007752	phosphorylation site [posttranslational modification]
585034007753	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
585034007754	putative periplasmic esterase; Provisional; Region: PRK03642
585034007755	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
585034007756	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
585034007757	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
585034007758	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
585034007759	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
585034007760	putative acetyltransferase; Provisional; Region: PRK03624
585034007761	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585034007762	Coenzyme A binding pocket [chemical binding]; other site
585034007763	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
585034007764	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
585034007765	active site
585034007766	metal binding site [ion binding]; metal-binding site
585034007767	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
585034007768	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
585034007769	transcriptional regulator EutR; Provisional; Region: PRK10130
585034007770	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034007771	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034007772	carboxysome structural protein EutK; Provisional; Region: PRK15466
585034007773	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
585034007774	Hexamer interface [polypeptide binding]; other site
585034007775	Hexagonal pore residue; other site
585034007776	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
585034007777	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
585034007778	putative hexamer interface [polypeptide binding]; other site
585034007779	putative hexagonal pore; other site
585034007780	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
585034007781	putative hexamer interface [polypeptide binding]; other site
585034007782	putative hexagonal pore; other site
585034007783	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
585034007784	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
585034007785	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
585034007786	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
585034007787	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
585034007788	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
585034007789	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
585034007790	active site
585034007791	metal binding site [ion binding]; metal-binding site
585034007792	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
585034007793	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
585034007794	nucleotide binding site [chemical binding]; other site
585034007795	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
585034007796	putative catalytic cysteine [active]
585034007797	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
585034007798	Hexamer/Pentamer interface [polypeptide binding]; other site
585034007799	central pore; other site
585034007800	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
585034007801	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
585034007802	Hexamer interface [polypeptide binding]; other site
585034007803	Putative hexagonal pore residue; other site
585034007804	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
585034007805	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
585034007806	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
585034007807	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
585034007808	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
585034007809	G1 box; other site
585034007810	GTP/Mg2+ binding site [chemical binding]; other site
585034007811	G2 box; other site
585034007812	Switch I region; other site
585034007813	G3 box; other site
585034007814	Switch II region; other site
585034007815	G4 box; other site
585034007816	G5 box; other site
585034007817	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
585034007818	putative hexamer interface [polypeptide binding]; other site
585034007819	putative hexagonal pore; other site
585034007820	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
585034007821	Malic enzyme, N-terminal domain; Region: malic; pfam00390
585034007822	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
585034007823	putative NAD(P) binding site [chemical binding]; other site
585034007824	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
585034007825	transaldolase-like protein; Provisional; Region: PTZ00411
585034007826	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
585034007827	active site
585034007828	dimer interface [polypeptide binding]; other site
585034007829	catalytic residue [active]
585034007830	transketolase; Reviewed; Region: PRK12753
585034007831	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
585034007832	TPP-binding site [chemical binding]; other site
585034007833	dimer interface [polypeptide binding]; other site
585034007834	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
585034007835	PYR/PP interface [polypeptide binding]; other site
585034007836	dimer interface [polypeptide binding]; other site
585034007837	TPP binding site [chemical binding]; other site
585034007838	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
585034007839	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
585034007840	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
585034007841	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
585034007842	dimer interface [polypeptide binding]; other site
585034007843	ADP-ribose binding site [chemical binding]; other site
585034007844	active site
585034007845	nudix motif; other site
585034007846	metal binding site [ion binding]; metal-binding site
585034007847	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
585034007848	4Fe-4S binding domain; Region: Fer4; pfam00037
585034007849	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
585034007850	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585034007851	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
585034007852	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
585034007853	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585034007854	dimerization interface [polypeptide binding]; other site
585034007855	Histidine kinase; Region: HisKA_3; pfam07730
585034007856	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034007857	ATP binding site [chemical binding]; other site
585034007858	Mg2+ binding site [ion binding]; other site
585034007859	G-X-G motif; other site
585034007860	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
585034007861	Protein export membrane protein; Region: SecD_SecF; cl14618
585034007862	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
585034007863	ArsC family; Region: ArsC; pfam03960
585034007864	putative catalytic residues [active]
585034007865	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
585034007866	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
585034007867	metal binding site [ion binding]; metal-binding site
585034007868	dimer interface [polypeptide binding]; other site
585034007869	hypothetical protein; Provisional; Region: PRK13664
585034007870	putative hydrolase; Provisional; Region: PRK11460
585034007871	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
585034007872	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
585034007873	Helicase; Region: Helicase_RecD; pfam05127
585034007874	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
585034007875	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
585034007876	Predicted metalloprotease [General function prediction only]; Region: COG2321
585034007877	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
585034007878	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
585034007879	oligomeric interface; other site
585034007880	putative active site [active]
585034007881	homodimer interface [polypeptide binding]; other site
585034007882	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
585034007883	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
585034007884	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
585034007885	ATP binding site [chemical binding]; other site
585034007886	active site
585034007887	substrate binding site [chemical binding]; other site
585034007888	lipoprotein; Provisional; Region: PRK11679
585034007889	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
585034007890	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
585034007891	dihydrodipicolinate synthase; Region: dapA; TIGR00674
585034007892	dimer interface [polypeptide binding]; other site
585034007893	active site
585034007894	catalytic residue [active]
585034007895	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
585034007896	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
585034007897	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
585034007898	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
585034007899	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
585034007900	catalytic triad [active]
585034007901	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
585034007902	4Fe-4S binding domain; Region: Fer4; pfam00037
585034007903	hydrogenase 4 subunit B; Validated; Region: PRK06521
585034007904	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
585034007905	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
585034007906	NADH dehydrogenase; Region: NADHdh; cl00469
585034007907	hydrogenase 4 subunit D; Validated; Region: PRK06525
585034007908	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
585034007909	hydrogenase 4 membrane subunit; Provisional; Region: hyfE; PRK11492
585034007910	hydrogenase 4 subunit F; Validated; Region: PRK06458
585034007911	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
585034007912	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
585034007913	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
585034007914	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
585034007915	hydrogenase 4 subunit H; Validated; Region: PRK08222
585034007916	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
585034007917	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
585034007918	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
585034007919	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains [Transcription / Signal transduction mechanisms]; Region: FhlA; COG3604
585034007920	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
585034007921	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034007922	Walker A motif; other site
585034007923	ATP binding site [chemical binding]; other site
585034007924	Walker B motif; other site
585034007925	arginine finger; other site
585034007926	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
585034007927	fragment of putative formate transporter (part 1);Evidence 7 : Gene remnant; Product type pt : putative transporter
585034007928	fragment of putative formate transporter (part 2);Evidence 7 : Gene remnant; Product type pt : putative transporter
585034007929	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
585034007930	Domain of unknown function DUF20; Region: UPF0118; pfam01594
585034007931	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
585034007932	Peptidase family M48; Region: Peptidase_M48; cl12018
585034007933	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
585034007934	ArsC family; Region: ArsC; pfam03960
585034007935	catalytic residues [active]
585034007936	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
585034007937	DNA replication initiation factor; Provisional; Region: PRK08084
585034007938	uracil transporter; Provisional; Region: PRK10720
585034007939	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
585034007940	active site
585034007941	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
585034007942	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
585034007943	dimerization interface [polypeptide binding]; other site
585034007944	putative ATP binding site [chemical binding]; other site
585034007945	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
585034007946	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
585034007947	active site
585034007948	substrate binding site [chemical binding]; other site
585034007949	cosubstrate binding site; other site
585034007950	catalytic site [active]
585034007951	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
585034007952	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
585034007953	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
585034007954	Catalytic C-terminal domain, first repeat, of prokaryotic polyphosphate kinase 1 and similar proteins; Region: PLDc_PPK1_C1; cd09114
585034007955	domain interface [polypeptide binding]; other site
585034007956	active site
585034007957	catalytic site [active]
585034007958	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
585034007959	putative active site [active]
585034007960	catalytic site [active]
585034007961	exopolyphosphatase; Provisional; Region: PRK10854
585034007962	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
585034007963	MASE1; Region: MASE1; pfam05231
585034007964	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
585034007965	diguanylate cyclase; Region: GGDEF; smart00267
585034007966	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585034007967	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
585034007968	GMP synthase; Reviewed; Region: guaA; PRK00074
585034007969	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
585034007970	AMP/PPi binding site [chemical binding]; other site
585034007971	candidate oxyanion hole; other site
585034007972	catalytic triad [active]
585034007973	potential glutamine specificity residues [chemical binding]; other site
585034007974	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
585034007975	ATP Binding subdomain [chemical binding]; other site
585034007976	Ligand Binding sites [chemical binding]; other site
585034007977	Dimerization subdomain; other site
585034007978	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
585034007979	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
585034007980	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
585034007981	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
585034007982	active site
585034007983	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
585034007984	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
585034007985	generic binding surface II; other site
585034007986	generic binding surface I; other site
585034007987	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
585034007988	GTP-binding protein Der; Reviewed; Region: PRK00093
585034007989	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
585034007990	G1 box; other site
585034007991	GTP/Mg2+ binding site [chemical binding]; other site
585034007992	Switch I region; other site
585034007993	G2 box; other site
585034007994	Switch II region; other site
585034007995	G3 box; other site
585034007996	G4 box; other site
585034007997	G5 box; other site
585034007998	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
585034007999	G1 box; other site
585034008000	GTP/Mg2+ binding site [chemical binding]; other site
585034008001	Switch I region; other site
585034008002	G2 box; other site
585034008003	G3 box; other site
585034008004	Switch II region; other site
585034008005	G4 box; other site
585034008006	G5 box; other site
585034008007	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
585034008008	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cd00216
585034008009	Trp docking motif [polypeptide binding]; other site
585034008010	active site
585034008011	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
585034008012	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
585034008013	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
585034008014	dimer interface [polypeptide binding]; other site
585034008015	motif 1; other site
585034008016	active site
585034008017	motif 2; other site
585034008018	motif 3; other site
585034008019	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
585034008020	anticodon binding site; other site
585034008021	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
585034008022	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
585034008023	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
585034008024	cytoskeletal protein RodZ; Provisional; Region: PRK10856
585034008025	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585034008026	non-specific DNA binding site [nucleotide binding]; other site
585034008027	salt bridge; other site
585034008028	sequence-specific DNA binding site [nucleotide binding]; other site
585034008029	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
585034008030	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
585034008031	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585034008032	FeS/SAM binding site; other site
585034008033	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
585034008034	active site
585034008035	multimer interface [polypeptide binding]; other site
585034008036	penicillin-binding protein 1C; Provisional; Region: PRK11240
585034008037	Transglycosylase; Region: Transgly; pfam00912
585034008038	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
585034008039	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
585034008040	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
585034008041	MG2 domain; Region: A2M_N; pfam01835
585034008042	Alpha-2-macroglobulin family; Region: A2M; pfam00207
585034008043	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
585034008044	surface patch; other site
585034008045	thioester region; other site
585034008046	specificity defining residues; other site
585034008047	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
585034008048	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
585034008049	active site residue [active]
585034008050	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
585034008051	active site residue [active]
585034008052	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
585034008053	aminopeptidase B; Provisional; Region: PRK05015
585034008054	Peptidase; Region: DUF3663; pfam12404
585034008055	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
585034008056	interface (dimer of trimers) [polypeptide binding]; other site
585034008057	Substrate-binding/catalytic site; other site
585034008058	Zn-binding sites [ion binding]; other site
585034008059	hypothetical protein; Provisional; Region: PRK10721
585034008060	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
585034008061	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
585034008062	catalytic loop [active]
585034008063	iron binding site [ion binding]; other site
585034008064	chaperone protein HscA; Provisional; Region: hscA; PRK05183
585034008065	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
585034008066	nucleotide binding site [chemical binding]; other site
585034008067	putative NEF/HSP70 interaction site [polypeptide binding]; other site
585034008068	SBD interface [polypeptide binding]; other site
585034008069	co-chaperone HscB; Provisional; Region: hscB; PRK05014
585034008070	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
585034008071	HSP70 interaction site [polypeptide binding]; other site
585034008072	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
585034008073	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
585034008074	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
585034008075	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
585034008076	trimerization site [polypeptide binding]; other site
585034008077	active site
585034008078	cysteine desulfurase; Provisional; Region: PRK14012
585034008079	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
585034008080	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
585034008081	catalytic residue [active]
585034008082	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
585034008083	Rrf2 family protein; Region: rrf2_super; TIGR00738
585034008084	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
585034008085	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
585034008086	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
585034008087	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
585034008088	active site
585034008089	dimerization interface [polypeptide binding]; other site
585034008090	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
585034008091	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
585034008092	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
585034008093	PRD domain; Region: PRD; pfam00874
585034008094	PRD domain; Region: PRD; pfam00874
585034008095	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
585034008096	MFS_1 like family; Region: MFS_1_like; pfam12832
585034008097	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
585034008098	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034008099	The C-terminal substrate binding domain of LysR-type transcriptional regulator HcaR in involved in 3-phenylpropionic acid catabolism, contains the type2 periplasmic binding fold; Region: PBP2_HcaR; cd08450
585034008100	putative dimerization interface [polypeptide binding]; other site
585034008101	putative substrate binding pocket [chemical binding]; other site
585034008102	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
585034008103	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
585034008104	iron-sulfur cluster [ion binding]; other site
585034008105	[2Fe-2S] cluster binding site [ion binding]; other site
585034008106	C-terminal catalytic domain of the oxygenase alpha subunit of naphthalene 1,2-dioxygenase (NDO) and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_NDO-like; cd08881
585034008107	beta subunit interface [polypeptide binding]; other site
585034008108	alpha subunit interface [polypeptide binding]; other site
585034008109	active site
585034008110	substrate binding site [chemical binding]; other site
585034008111	Fe binding site [ion binding]; other site
585034008112	Ring hydroxylating dioxygenase beta subunit. This subunit has a similar structure to NTF-2, Ketosteroid isomerase and scytalone dehydratase.The degradation of aromatic compounds by aerobic bacteria frequently begins with the dihydroxylation of the...; Region: ring_hydroxylating_dioxygenases_beta; cd00667
585034008113	inter-subunit interface; other site
585034008114	Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528
585034008115	[2Fe-2S] cluster binding site [ion binding]; other site
585034008116	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase; Provisional; Region: PRK06200
585034008117	cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase (BphB)-like, classical (c) SDRs; Region: BphB-like_SDR_c; cd05348
585034008118	NAD binding site [chemical binding]; other site
585034008119	active site
585034008120	fragment of phenylpropionate dioxygenase, ferredoxin reductase subunit (part 1);Evidence 7 : Gene remnant; Product type e : enzyme
585034008121	fragment of phenylpropionate dioxygenase, ferredoxin reductase subunit (part 2);Evidence 7 : Gene remnant; Product type e : enzyme
585034008122	Predicted membrane protein [Function unknown]; Region: COG2259
585034008123	aldose 1-epimerase, similar to Escherichia coli YphB; Region: Aldose_epim_Ec_YphB; cd09021
585034008124	active site
585034008125	catalytic residues [active]
585034008126	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
585034008127	L-threonine dehydrogenase (TDH)-like; Region: THR_DH_like; cd08239
585034008128	putative NAD(P) binding site [chemical binding]; other site
585034008129	catalytic Zn binding site [ion binding]; other site
585034008130	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585034008131	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585034008132	TM-ABC transporter signature motif; other site
585034008133	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
585034008134	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
585034008135	Walker A/P-loop; other site
585034008136	ATP binding site [chemical binding]; other site
585034008137	Q-loop/lid; other site
585034008138	ABC transporter signature motif; other site
585034008139	Walker B; other site
585034008140	D-loop; other site
585034008141	H-loop/switch region; other site
585034008142	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
585034008143	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
585034008144	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
585034008145	ligand binding site [chemical binding]; other site
585034008146	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585034008147	TPR motif; other site
585034008148	Tetratricopeptide repeat; Region: TPR_16; pfam13432
585034008149	binding surface
585034008150	TPR repeat; Region: TPR_11; pfam13414
585034008151	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585034008152	TPR motif; other site
585034008153	binding surface
585034008154	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
585034008155	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
585034008156	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
585034008157	nucleotide binding site [chemical binding]; other site
585034008158	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
585034008159	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
585034008160	dimer interface [polypeptide binding]; other site
585034008161	active site
585034008162	glycine-pyridoxal phosphate binding site [chemical binding]; other site
585034008163	folate binding site [chemical binding]; other site
585034008164	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
585034008165	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
585034008166	heme-binding site [chemical binding]; other site
585034008167	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
585034008168	FAD binding pocket [chemical binding]; other site
585034008169	FAD binding motif [chemical binding]; other site
585034008170	phosphate binding motif [ion binding]; other site
585034008171	beta-alpha-beta structure motif; other site
585034008172	NAD binding pocket [chemical binding]; other site
585034008173	Heme binding  pocket [chemical binding]; other site
585034008174	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
585034008175	Nitrogen regulatory protein P-II; Region: P-II; smart00938
585034008176	response regulator GlrR; Provisional; Region: PRK15115
585034008177	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034008178	active site
585034008179	phosphorylation site [posttranslational modification]
585034008180	intermolecular recognition site; other site
585034008181	dimerization interface [polypeptide binding]; other site
585034008182	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034008183	Walker A motif; other site
585034008184	ATP binding site [chemical binding]; other site
585034008185	Walker B motif; other site
585034008186	arginine finger; other site
585034008187	hypothetical protein; Provisional; Region: PRK10722
585034008188	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
585034008189	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585034008190	dimer interface [polypeptide binding]; other site
585034008191	phosphorylation site [posttranslational modification]
585034008192	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034008193	ATP binding site [chemical binding]; other site
585034008194	Mg2+ binding site [ion binding]; other site
585034008195	G-X-G motif; other site
585034008196	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
585034008197	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
585034008198	dimerization interface [polypeptide binding]; other site
585034008199	ATP binding site [chemical binding]; other site
585034008200	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
585034008201	dimerization interface [polypeptide binding]; other site
585034008202	ATP binding site [chemical binding]; other site
585034008203	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
585034008204	putative active site [active]
585034008205	catalytic triad [active]
585034008206	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
585034008207	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585034008208	substrate binding pocket [chemical binding]; other site
585034008209	membrane-bound complex binding site; other site
585034008210	hinge residues; other site
585034008211	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
585034008212	N-acetyl-D-glucosamine binding site [chemical binding]; other site
585034008213	catalytic residue [active]
585034008214	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
585034008215	nucleoside/Zn binding site; other site
585034008216	dimer interface [polypeptide binding]; other site
585034008217	catalytic motif [active]
585034008218	hypothetical protein; Provisional; Region: PRK11590
585034008219	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
585034008220	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
585034008221	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
585034008222	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
585034008223	putative active site [active]
585034008224	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
585034008225	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
585034008226	Protein of unknown function (DUF2612); Region: DUF2612; pfam11041
585034008227	Baseplate J-like protein; Region: Baseplate_J; cl01294
585034008228	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
585034008229	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
585034008230	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
585034008231	virion protein; Provisional; Region: V; PHA02564
585034008232	Protein of unknown function (DUF3277); Region: DUF3277; pfam11681
585034008233	Protein of unknown function (DUF3383); Region: DUF3383; pfam11863
585034008234	Guanylyl transferase CofC like; Region: CofC; cl17472
585034008235	Superfamily II helicase, archaea-specific [General function prediction only]; Region: COG1202
585034008236	Protein of unknown function (DUF4054); Region: DUF4054; pfam13262
585034008237	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4834
585034008238	Uncharacterized protein conserved in bacteria (DUF2184); Region: DUF2184; pfam09950
585034008239	Uncharacterized protein conserved in bacteria (DUF2213); Region: DUF2213; pfam09979
585034008240	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
585034008241	phage-related protein, HI1409 family; Region: phge_rel_HI1409; TIGR01555
585034008242	Protein of unknown function (DUF1073); Region: DUF1073; pfam06381
585034008243	Terminase small subunit; Region: Terminase_2; pfam03592
585034008244	The lysozyme from bacteriophage lambda hydrolyses the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc), as do other lysozymes.  But unlike other lysozymes, bacteriophage lambda does not produce a reducing...; Region: bacteriophage_lambda_lysozyme; cd00736
585034008245	N-acetyl-D-glucosamine binding site [chemical binding]; other site
585034008246	catalytic residue [active]
585034008247	Phage holin family (Lysis protein S); Region: Phage_holin_3; cl04938
585034008248	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
585034008249	Prim_Pol: Primase-polymerase (primpol) domain of the type found in bifunctional replicases from archaeal plasmids, including ORF904 protein of the crenarchaeal plasmid pRN1 from Sulfolobus islandicus (pRN1 primpol). These primpol domains belong to the...; Region: Prim_Pol; cd04859
585034008250	polymerase nucleotide-binding site; other site
585034008251	DNA-binding residues [nucleotide binding]; DNA binding site
585034008252	nucleotide binding site [chemical binding]; other site
585034008253	primase nucleotide-binding site [nucleotide binding]; other site
585034008254	Virulence-associated protein E; Region: VirE; pfam05272
585034008255	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585034008256	sequence-specific DNA binding site [nucleotide binding]; other site
585034008257	salt bridge; other site
585034008258	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585034008259	non-specific DNA binding site [nucleotide binding]; other site
585034008260	Predicted transcriptional regulator [Transcription]; Region: COG2932
585034008261	salt bridge; other site
585034008262	sequence-specific DNA binding site [nucleotide binding]; other site
585034008263	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
585034008264	Catalytic site [active]
585034008265	Protein of unknown function (DUF2800); Region: DUF2800; pfam10926
585034008266	Protein of unknown function (DUF2815); Region: DUF2815; pfam10991
585034008267	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
585034008268	active site
585034008269	substrate binding site [chemical binding]; other site
585034008270	Family A polymerase primarily fills DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A; cl02626
585034008271	active site
585034008272	DNA binding site [nucleotide binding]
585034008273	catalytic site [active]
585034008274	Predicted nucleotide-binding protein containing TIR-like domain; Region: TIR-like; cl17861
585034008275	VRR-NUC domain; Region: VRR_NUC; pfam08774
585034008276	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
585034008277	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585034008278	nucleotide binding region [chemical binding]; other site
585034008279	ATP-binding site [chemical binding]; other site
585034008280	Helix-turn-helix domain; Region: HTH_17; pfam12728
585034008281	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
585034008282	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
585034008283	holo-[acyl-carrier-protein] synthase; Region: acpS; TIGR00516
585034008284	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
585034008285	active site
585034008286	hydrophilic channel; other site
585034008287	dimerization interface [polypeptide binding]; other site
585034008288	catalytic residues [active]
585034008289	active site lid [active]
585034008290	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
585034008291	Recombination protein O N terminal; Region: RecO_N; pfam11967
585034008292	Recombination protein O C terminal; Region: RecO_C; pfam02565
585034008293	GTPase Era; Reviewed; Region: era; PRK00089
585034008294	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
585034008295	G1 box; other site
585034008296	GTP/Mg2+ binding site [chemical binding]; other site
585034008297	Switch I region; other site
585034008298	G2 box; other site
585034008299	Switch II region; other site
585034008300	G3 box; other site
585034008301	G4 box; other site
585034008302	G5 box; other site
585034008303	KH domain; Region: KH_2; pfam07650
585034008304	ribonuclease III; Reviewed; Region: rnc; PRK00102
585034008305	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
585034008306	dimerization interface [polypeptide binding]; other site
585034008307	active site
585034008308	metal binding site [ion binding]; metal-binding site
585034008309	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
585034008310	dsRNA binding site [nucleotide binding]; other site
585034008311	signal peptidase I; Provisional; Region: PRK10861
585034008312	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
585034008313	Catalytic site [active]
585034008314	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
585034008315	GTP-binding protein LepA; Provisional; Region: PRK05433
585034008316	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
585034008317	G1 box; other site
585034008318	putative GEF interaction site [polypeptide binding]; other site
585034008319	GTP/Mg2+ binding site [chemical binding]; other site
585034008320	Switch I region; other site
585034008321	G2 box; other site
585034008322	G3 box; other site
585034008323	Switch II region; other site
585034008324	G4 box; other site
585034008325	G5 box; other site
585034008326	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
585034008327	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
585034008328	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
585034008329	SoxR reducing system protein RseC; Provisional; Region: PRK10862
585034008330	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
585034008331	anti-sigma E factor; Provisional; Region: rseB; PRK09455
585034008332	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
585034008333	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
585034008334	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
585034008335	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
585034008336	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
585034008337	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
585034008338	DNA binding residues [nucleotide binding]
585034008339	L-aspartate oxidase; Provisional; Region: PRK09077
585034008340	L-aspartate oxidase; Provisional; Region: PRK06175
585034008341	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
585034008342	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
585034008343	Methyltransferase domain; Region: Methyltransf_26; pfam13659
585034008344	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
585034008345	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
585034008346	ATP binding site [chemical binding]; other site
585034008347	Mg++ binding site [ion binding]; other site
585034008348	motif III; other site
585034008349	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585034008350	nucleotide binding region [chemical binding]; other site
585034008351	ATP-binding site [chemical binding]; other site
585034008352	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
585034008353	Transposase; Region: DEDD_Tnp_IS110; pfam01548
585034008354	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
585034008355	Transcriptional regulator [Transcription]; Region: LysR; COG0583
585034008356	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034008357	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
585034008358	dimerization interface [polypeptide binding]; other site
585034008359	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
585034008360	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
585034008361	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
585034008362	ligand binding site [chemical binding]; other site
585034008363	active site
585034008364	UGI interface [polypeptide binding]; other site
585034008365	catalytic site [active]
585034008366	putative methyltransferase; Provisional; Region: PRK10864
585034008367	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
585034008368	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
585034008369	thioredoxin 2; Provisional; Region: PRK10996
585034008370	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
585034008371	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
585034008372	catalytic residues [active]
585034008373	Uncharacterized conserved protein [Function unknown]; Region: COG3148
585034008374	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
585034008375	CoA binding domain; Region: CoA_binding_2; pfam13380
585034008376	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
585034008377	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
585034008378	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
585034008379	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
585034008380	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
585034008381	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
585034008382	domain interface [polypeptide binding]; other site
585034008383	putative active site [active]
585034008384	catalytic site [active]
585034008385	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
585034008386	domain interface [polypeptide binding]; other site
585034008387	putative active site [active]
585034008388	catalytic site [active]
585034008389	lipoprotein; Provisional; Region: PRK10759
585034008390	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
585034008391	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034008392	putative substrate translocation pore; other site
585034008393	protein disaggregation chaperone; Provisional; Region: PRK10865
585034008394	Clp amino terminal domain; Region: Clp_N; pfam02861
585034008395	Clp amino terminal domain; Region: Clp_N; pfam02861
585034008396	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034008397	Walker A motif; other site
585034008398	ATP binding site [chemical binding]; other site
585034008399	Walker B motif; other site
585034008400	arginine finger; other site
585034008401	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034008402	Walker A motif; other site
585034008403	ATP binding site [chemical binding]; other site
585034008404	Walker B motif; other site
585034008405	arginine finger; other site
585034008406	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
585034008407	hypothetical protein; Provisional; Region: PRK10723
585034008408	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
585034008409	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
585034008410	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
585034008411	RNA binding surface [nucleotide binding]; other site
585034008412	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
585034008413	active site
585034008414	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
585034008415	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
585034008416	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
585034008417	30S subunit binding site; other site
585034008418	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
585034008419	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
585034008420	Prephenate dehydratase; Region: PDT; pfam00800
585034008421	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
585034008422	putative L-Phe binding site [chemical binding]; other site
585034008423	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
585034008424	Chorismate mutase type II; Region: CM_2; cl00693
585034008425	prephenate dehydrogenase; Validated; Region: PRK08507
585034008426	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
585034008427	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
585034008428	lipoprotein; Provisional; Region: PRK11443
585034008429	Protein of unknown function (DUF2799); Region: DUF2799; pfam10973
585034008430	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
585034008431	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
585034008432	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585034008433	metal binding site [ion binding]; metal-binding site
585034008434	active site
585034008435	I-site; other site
585034008436	putative outer membrane lipoprotein; Provisional; Region: PRK09967
585034008437	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
585034008438	ligand binding site [chemical binding]; other site
585034008439	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
585034008440	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
585034008441	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
585034008442	RimM N-terminal domain; Region: RimM; pfam01782
585034008443	PRC-barrel domain; Region: PRC; pfam05239
585034008444	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
585034008445	signal recognition particle protein; Provisional; Region: PRK10867
585034008446	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
585034008447	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
585034008448	P loop; other site
585034008449	GTP binding site [chemical binding]; other site
585034008450	Signal peptide binding domain; Region: SRP_SPB; pfam02978
585034008451	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
585034008452	hypothetical protein; Provisional; Region: PRK11573
585034008453	Domain of unknown function DUF21; Region: DUF21; pfam01595
585034008454	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
585034008455	Transporter associated domain; Region: CorC_HlyC; smart01091
585034008456	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
585034008457	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
585034008458	dimer interface [polypeptide binding]; other site
585034008459	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
585034008460	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
585034008461	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
585034008462	recombination and repair protein; Provisional; Region: PRK10869
585034008463	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
585034008464	Walker A/P-loop; other site
585034008465	ATP binding site [chemical binding]; other site
585034008466	Q-loop/lid; other site
585034008467	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
585034008468	Q-loop/lid; other site
585034008469	ABC transporter signature motif; other site
585034008470	Walker B; other site
585034008471	D-loop; other site
585034008472	H-loop/switch region; other site
585034008473	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
585034008474	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
585034008475	hypothetical protein; Validated; Region: PRK01777
585034008476	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
585034008477	putative coenzyme Q binding site [chemical binding]; other site
585034008478	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
585034008479	SmpB-tmRNA interface; other site
585034008480	fragment of adhesin-like autotransporter (part 3);Evidence 7 : Gene remnant; Product type t : transporter
585034008481	fragment of adhesin-like autotransporter (part 2);Evidence 7 : Gene remnant; Product type t : transporter
585034008482	Transposase; Region: HTH_Tnp_1; pfam01527
585034008483	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
585034008484	HTH-like domain; Region: HTH_21; pfam13276
585034008485	Integrase core domain; Region: rve; pfam00665
585034008486	Integrase core domain; Region: rve_3; pfam13683
585034008487	fragment of adhesin-like autotransporter (part 1);Evidence 7 : Gene remnant; Product type t : transporter
585034008488	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
585034008489	catalytic residues [active]
585034008490	fragment of conserved hypothetical protein from bacteriophage origin (part 2);Evidence 7 : Gene remnant
585034008491	fragment of conserved hypothetical protein from bacteriophage origin (part 1);Evidence 7 : Gene remnant
585034008492	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
585034008493	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
585034008494	active site
585034008495	catalytic site [active]
585034008496	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; cl02706
585034008497	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
585034008498	substrate binding pocket [chemical binding]; other site
585034008499	active site
585034008500	iron coordination sites [ion binding]; other site
585034008501	Predicted dehydrogenase [General function prediction only]; Region: COG0579
585034008502	hydroxyglutarate oxidase; Provisional; Region: PRK11728
585034008503	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
585034008504	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
585034008505	tetramerization interface [polypeptide binding]; other site
585034008506	NAD(P) binding site [chemical binding]; other site
585034008507	catalytic residues [active]
585034008508	4-aminobutyrate aminotransferase; Validated; Region: PRK08088
585034008509	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
585034008510	inhibitor-cofactor binding pocket; inhibition site
585034008511	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034008512	catalytic residue [active]
585034008513	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
585034008514	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
585034008515	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034008516	DNA-binding site [nucleotide binding]; DNA binding site
585034008517	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
585034008518	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
585034008519	bacterial OsmY and nodulation domain; Region: BON; smart00749
585034008520	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
585034008521	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
585034008522	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
585034008523	dimerization interface [polypeptide binding]; other site
585034008524	putative DNA binding site [nucleotide binding]; other site
585034008525	Transcriptional regulators [Transcription]; Region: MarR; COG1846
585034008526	putative Zn2+ binding site [ion binding]; other site
585034008527	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YgaP, and similar uncharacterized putative rhodanese-related sulfurtransferases; Region: RHOD_YgaP; cd01527
585034008528	active site residue [active]
585034008529	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
585034008530	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
585034008531	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
585034008532	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
585034008533	hypothetical protein; Provisional; Region: PRK10556
585034008534	hypothetical protein; Provisional; Region: PRK10132
585034008535	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
585034008536	catalytic residues [active]
585034008537	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
585034008538	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
585034008539	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
585034008540	Class I ribonucleotide reductase; Region: RNR_I; cd01679
585034008541	active site
585034008542	dimer interface [polypeptide binding]; other site
585034008543	catalytic residues [active]
585034008544	effector binding site; other site
585034008545	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
585034008546	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
585034008547	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
585034008548	dimer interface [polypeptide binding]; other site
585034008549	putative radical transfer pathway; other site
585034008550	diiron center [ion binding]; other site
585034008551	tyrosyl radical; other site
585034008552	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
585034008553	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
585034008554	Walker A/P-loop; other site
585034008555	ATP binding site [chemical binding]; other site
585034008556	Q-loop/lid; other site
585034008557	ABC transporter signature motif; other site
585034008558	Walker B; other site
585034008559	D-loop; other site
585034008560	H-loop/switch region; other site
585034008561	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
585034008562	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
585034008563	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034008564	dimer interface [polypeptide binding]; other site
585034008565	conserved gate region; other site
585034008566	putative PBP binding loops; other site
585034008567	ABC-ATPase subunit interface; other site
585034008568	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
585034008569	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
585034008570	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
585034008571	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034008572	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
585034008573	putative L-valine exporter; Provisional; Region: PRK10408
585034008574	transcriptional repressor MprA; Provisional; Region: PRK10870
585034008575	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
585034008576	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
585034008577	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585034008578	HlyD family secretion protein; Region: HlyD_3; pfam13437
585034008579	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
585034008580	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034008581	putative substrate translocation pore; other site
585034008582	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034008583	S-ribosylhomocysteinase; Provisional; Region: PRK02260
585034008584	glutamate--cysteine ligase; Provisional; Region: PRK02107
585034008585	Predicted membrane protein [Function unknown]; Region: COG1238
585034008586	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
585034008587	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034008588	motif II; other site
585034008589	carbon storage regulator; Provisional; Region: PRK01712
585034008590	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
585034008591	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
585034008592	motif 1; other site
585034008593	active site
585034008594	motif 2; other site
585034008595	motif 3; other site
585034008596	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
585034008597	DHHA1 domain; Region: DHHA1; pfam02272
585034008598	recombination regulator RecX; Reviewed; Region: recX; PRK00117
585034008599	recombinase A; Provisional; Region: recA; PRK09354
585034008600	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
585034008601	hexamer interface [polypeptide binding]; other site
585034008602	Walker A motif; other site
585034008603	ATP binding site [chemical binding]; other site
585034008604	Walker B motif; other site
585034008605	hypothetical protein; Validated; Region: PRK03661
585034008606	Transglycosylase SLT domain; Region: SLT_2; pfam13406
585034008607	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
585034008608	N-acetyl-D-glucosamine binding site [chemical binding]; other site
585034008609	PTS system, glucitol/sorbitol-specific, IIC component; Region: EII-GUT; TIGR00821
585034008610	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
585034008611	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
585034008612	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
585034008613	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
585034008614	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
585034008615	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
585034008616	putative NAD(P) binding site [chemical binding]; other site
585034008617	active site
585034008618	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
585034008619	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
585034008620	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
585034008621	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585034008622	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
585034008623	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
585034008624	putative active site [active]
585034008625	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
585034008626	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
585034008627	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
585034008628	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034008629	Walker A motif; other site
585034008630	ATP binding site [chemical binding]; other site
585034008631	Walker B motif; other site
585034008632	arginine finger; other site
585034008633	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
585034008634	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
585034008635	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
585034008636	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
585034008637	iron binding site [ion binding]; other site
585034008638	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
585034008639	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585034008640	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
585034008641	Acylphosphatase; Region: Acylphosphatase; pfam00708
585034008642	HypF finger; Region: zf-HYPF; pfam07503
585034008643	HypF finger; Region: zf-HYPF; pfam07503
585034008644	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
585034008645	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
585034008646	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
585034008647	Transcriptional regulators [Transcription]; Region: PurR; COG1609
585034008648	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585034008649	DNA binding site [nucleotide binding]
585034008650	domain linker motif; other site
585034008651	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
585034008652	dimerization interface (closed form) [polypeptide binding]; other site
585034008653	ligand binding site [chemical binding]; other site
585034008654	PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional; Region: PRK09796
585034008655	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
585034008656	active site turn [active]
585034008657	phosphorylation site [posttranslational modification]
585034008658	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
585034008659	cryptic 6-phospho-beta-glucosidase; Provisional; Region: PRK09852
585034008660	beta-galactosidase; Region: BGL; TIGR03356
585034008661	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585034008662	non-specific DNA binding site [nucleotide binding]; other site
585034008663	salt bridge; other site
585034008664	sequence-specific DNA binding site [nucleotide binding]; other site
585034008665	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
585034008666	nickel binding site [ion binding]; other site
585034008667	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
585034008668	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
585034008669	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
585034008670	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
585034008671	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
585034008672	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
585034008673	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
585034008674	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
585034008675	NADH dehydrogenase; Region: NADHdh; cl00469
585034008676	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
585034008677	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
585034008678	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
585034008679	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
585034008680	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
585034008681	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
585034008682	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
585034008683	hydrogenase assembly chaperone; Provisional; Region: PRK10409
585034008684	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
585034008685	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
585034008686	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
585034008687	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
585034008688	dimerization interface [polypeptide binding]; other site
585034008689	ATP binding site [chemical binding]; other site
585034008690	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
585034008691	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
585034008692	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
585034008693	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034008694	Walker A motif; other site
585034008695	ATP binding site [chemical binding]; other site
585034008696	Walker B motif; other site
585034008697	arginine finger; other site
585034008698	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
585034008699	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
585034008700	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
585034008701	MutS domain I; Region: MutS_I; pfam01624
585034008702	MutS domain II; Region: MutS_II; pfam05188
585034008703	MutS domain III; Region: MutS_III; pfam05192
585034008704	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
585034008705	Walker A/P-loop; other site
585034008706	ATP binding site [chemical binding]; other site
585034008707	Q-loop/lid; other site
585034008708	ABC transporter signature motif; other site
585034008709	Walker B; other site
585034008710	D-loop; other site
585034008711	H-loop/switch region; other site
585034008712	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
585034008713	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
585034008714	active site
585034008715	metal binding site [ion binding]; metal-binding site
585034008716	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
585034008717	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
585034008718	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585034008719	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
585034008720	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
585034008721	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
585034008722	putative aldolase; Validated; Region: PRK08130
585034008723	active site
585034008724	intersubunit interface [polypeptide binding]; other site
585034008725	Zn2+ binding site [ion binding]; other site
585034008726	hypothetical protein; Provisional; Region: PRK09989
585034008727	putative transporter; Provisional; Region: PRK09821
585034008728	GntP family permease; Region: GntP_permease; pfam02447
585034008729	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
585034008730	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
585034008731	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
585034008732	Flavoprotein; Region: Flavoprotein; pfam02441
585034008733	MarR family; Region: MarR_2; cl17246
585034008734	Transcriptional regulators [Transcription]; Region: MarR; COG1846
585034008735	fragment of RNA polymerase, sigma S (sigma 38) factor (part 2);Evidence 7 : Gene remnant; Product type f : factor
585034008736	fragment of RNA polymerase, sigma S (sigma 38) factor (part 1);Evidence 7 : Gene remnant; Product type f : factor
585034008737	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
585034008738	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
585034008739	Peptidase family M23; Region: Peptidase_M23; pfam01551
585034008740	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
585034008741	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034008742	S-adenosylmethionine binding site [chemical binding]; other site
585034008743	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
585034008744	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
585034008745	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
585034008746	Permutation of conserved domain; other site
585034008747	active site
585034008748	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
585034008749	homotrimer interaction site [polypeptide binding]; other site
585034008750	zinc binding site [ion binding]; other site
585034008751	CDP-binding sites; other site
585034008752	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
585034008753	substrate binding site; other site
585034008754	dimer interface; other site
585034008755	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
585034008756	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
585034008757	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
585034008758	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
585034008759	ligand-binding site [chemical binding]; other site
585034008760	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
585034008761	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
585034008762	CysD dimerization site [polypeptide binding]; other site
585034008763	G1 box; other site
585034008764	putative GEF interaction site [polypeptide binding]; other site
585034008765	GTP/Mg2+ binding site [chemical binding]; other site
585034008766	Switch I region; other site
585034008767	G2 box; other site
585034008768	G3 box; other site
585034008769	Switch II region; other site
585034008770	G4 box; other site
585034008771	G5 box; other site
585034008772	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
585034008773	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
585034008774	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
585034008775	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
585034008776	Active Sites [active]
585034008777	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
585034008778	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
585034008779	metal binding site [ion binding]; metal-binding site
585034008780	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I-E; cd09648
585034008781	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-E; cd09719
585034008782	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09664
585034008783	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
585034008784	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
585034008785	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-E; cd09646
585034008786	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cd09670
585034008787	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669
585034008788	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
585034008789	CRISPR-associated helicase Cas3 [Defense mechanisms]; Region: COG1203
585034008790	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
585034008791	Hok/gef family; Region: HOK_GEF; pfam01848
585034008792	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
585034008793	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
585034008794	Active Sites [active]
585034008795	sulfite reductase subunit beta; Provisional; Region: PRK13504
585034008796	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
585034008797	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
585034008798	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
585034008799	Flavodoxin; Region: Flavodoxin_1; pfam00258
585034008800	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
585034008801	FAD binding pocket [chemical binding]; other site
585034008802	FAD binding motif [chemical binding]; other site
585034008803	catalytic residues [active]
585034008804	NAD binding pocket [chemical binding]; other site
585034008805	phosphate binding motif [ion binding]; other site
585034008806	beta-alpha-beta structure motif; other site
585034008807	6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a...; Region: PTPS; cd00470
585034008808	homohexamer interface [polypeptide binding]; other site
585034008809	putative substrate stabilizing pore; other site
585034008810	pterin binding site; other site
585034008811	putative oxidoreductase FixC; Provisional; Region: PRK10157
585034008812	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
585034008813	Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]; Region: GlpP; COG1954
585034008814	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
585034008815	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
585034008816	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
585034008817	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
585034008818	Ligand binding site [chemical binding]; other site
585034008819	Electron transfer flavoprotein domain; Region: ETF; pfam01012
585034008820	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
585034008821	benzoate transport; Region: 2A0115; TIGR00895
585034008822	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034008823	putative substrate translocation pore; other site
585034008824	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
585034008825	FAD binding domain; Region: FAD_binding_4; pfam01565
585034008826	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK06935
585034008827	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
585034008828	NADP binding site [chemical binding]; other site
585034008829	homodimer interface [polypeptide binding]; other site
585034008830	active site
585034008831	Major Facilitator Superfamily; Region: MFS_1; pfam07690
585034008832	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034008833	putative substrate translocation pore; other site
585034008834	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
585034008835	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
585034008836	nucleotide binding site [chemical binding]; other site
585034008837	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
585034008838	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
585034008839	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
585034008840	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
585034008841	Repair protein; Region: Repair_PSII; pfam04536
585034008842	enolase; Provisional; Region: eno; PRK00077
585034008843	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
585034008844	dimer interface [polypeptide binding]; other site
585034008845	metal binding site [ion binding]; metal-binding site
585034008846	substrate binding pocket [chemical binding]; other site
585034008847	CTP synthetase; Validated; Region: pyrG; PRK05380
585034008848	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
585034008849	Catalytic site [active]
585034008850	active site
585034008851	UTP binding site [chemical binding]; other site
585034008852	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
585034008853	active site
585034008854	putative oxyanion hole; other site
585034008855	catalytic triad [active]
585034008856	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
585034008857	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
585034008858	homodimer interface [polypeptide binding]; other site
585034008859	metal binding site [ion binding]; metal-binding site
585034008860	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
585034008861	homodimer interface [polypeptide binding]; other site
585034008862	active site
585034008863	putative chemical substrate binding site [chemical binding]; other site
585034008864	metal binding site [ion binding]; metal-binding site
585034008865	toxin MazF; Provisional; Region: PRK09907
585034008866	antitoxin MazE; Provisional; Region: PRK09798
585034008867	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
585034008868	HD domain; Region: HD_4; pfam13328
585034008869	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
585034008870	synthetase active site [active]
585034008871	NTP binding site [chemical binding]; other site
585034008872	metal binding site [ion binding]; metal-binding site
585034008873	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
585034008874	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
585034008875	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
585034008876	TRAM domain; Region: TRAM; pfam01938
585034008877	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034008878	S-adenosylmethionine binding site [chemical binding]; other site
585034008879	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
585034008880	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
585034008881	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585034008882	dimerization interface [polypeptide binding]; other site
585034008883	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585034008884	dimer interface [polypeptide binding]; other site
585034008885	phosphorylation site [posttranslational modification]
585034008886	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034008887	ATP binding site [chemical binding]; other site
585034008888	Mg2+ binding site [ion binding]; other site
585034008889	G-X-G motif; other site
585034008890	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
585034008891	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034008892	active site
585034008893	phosphorylation site [posttranslational modification]
585034008894	intermolecular recognition site; other site
585034008895	dimerization interface [polypeptide binding]; other site
585034008896	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
585034008897	putative binding surface; other site
585034008898	active site
585034008899	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
585034008900	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
585034008901	active site
585034008902	tetramer interface [polypeptide binding]; other site
585034008903	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
585034008904	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
585034008905	active site
585034008906	tetramer interface [polypeptide binding]; other site
585034008907	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034008908	D-galactonate transporter; Region: 2A0114; TIGR00893
585034008909	putative substrate translocation pore; other site
585034008910	flavodoxin; Provisional; Region: PRK08105
585034008911	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
585034008912	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
585034008913	probable active site [active]
585034008914	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
585034008915	SecY interacting protein Syd; Provisional; Region: PRK04968
585034008916	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
585034008917	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
585034008918	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
585034008919	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
585034008920	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
585034008921	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
585034008922	serine transporter; Region: stp; TIGR00814
585034008923	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
585034008924	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
585034008925	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
585034008926	flap endonuclease-like protein; Provisional; Region: PRK09482
585034008927	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
585034008928	active site
585034008929	metal binding site 1 [ion binding]; metal-binding site
585034008930	putative 5' ssDNA interaction site; other site
585034008931	metal binding site 3; metal-binding site
585034008932	metal binding site 2 [ion binding]; metal-binding site
585034008933	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
585034008934	putative DNA binding site [nucleotide binding]; other site
585034008935	putative metal binding site [ion binding]; other site
585034008936	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
585034008937	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
585034008938	dimer interface [polypeptide binding]; other site
585034008939	active site
585034008940	metal binding site [ion binding]; metal-binding site
585034008941	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
585034008942	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
585034008943	intersubunit interface [polypeptide binding]; other site
585034008944	active site
585034008945	Zn2+ binding site [ion binding]; other site
585034008946	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
585034008947	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034008948	putative substrate translocation pore; other site
585034008949	L-fucose isomerase; Provisional; Region: fucI; PRK10991
585034008950	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
585034008951	hexamer (dimer of trimers) interface [polypeptide binding]; other site
585034008952	trimer interface [polypeptide binding]; other site
585034008953	substrate binding site [chemical binding]; other site
585034008954	Mn binding site [ion binding]; other site
585034008955	L-fuculokinase; Provisional; Region: PRK10331
585034008956	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
585034008957	nucleotide binding site [chemical binding]; other site
585034008958	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
585034008959	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
585034008960	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
585034008961	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585034008962	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
585034008963	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
585034008964	hypothetical protein; Provisional; Region: PRK10873
585034008965	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
585034008966	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034008967	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
585034008968	dimerization interface [polypeptide binding]; other site
585034008969	substrate binding pocket [chemical binding]; other site
585034008970	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
585034008971	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
585034008972	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
585034008973	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
585034008974	catalytic residue [active]
585034008975	CsdA-binding activator; Provisional; Region: PRK15019
585034008976	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
585034008977	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
585034008978	putative ATP binding site [chemical binding]; other site
585034008979	putative substrate interface [chemical binding]; other site
585034008980	murein transglycosylase A; Provisional; Region: mltA; PRK11162
585034008981	MltA specific insert domain; Region: MltA; pfam03562
585034008982	3D domain; Region: 3D; pfam06725
585034008983	AMIN domain; Region: AMIN; pfam11741
585034008984	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
585034008985	active site
585034008986	metal binding site [ion binding]; metal-binding site
585034008987	N-acetylglutamate synthase; Validated; Region: PRK05279
585034008988	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
585034008989	putative feedback inhibition sensing region; other site
585034008990	putative nucleotide binding site [chemical binding]; other site
585034008991	putative substrate binding site [chemical binding]; other site
585034008992	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585034008993	Coenzyme A binding pocket [chemical binding]; other site
585034008994	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
585034008995	AAA domain; Region: AAA_30; pfam13604
585034008996	Family description; Region: UvrD_C_2; pfam13538
585034008997	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
585034008998	protease3; Provisional; Region: PRK15101
585034008999	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
585034009000	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
585034009001	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
585034009002	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
585034009003	exodeoxyribonuclease V, gamma subunit; Region: recC; TIGR01450
585034009004	hypothetical protein; Provisional; Region: PRK10332
585034009005	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
585034009006	hypothetical protein; Provisional; Region: PRK11521
585034009007	hypothetical protein; Provisional; Region: PRK10557
585034009008	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
585034009009	hypothetical protein; Provisional; Region: PRK10506
585034009010	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
585034009011	thymidylate synthase; Reviewed; Region: thyA; PRK01827
585034009012	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
585034009013	dimerization interface [polypeptide binding]; other site
585034009014	active site
585034009015	prolipoprotein diacylglyceryl transferase; Region: lgt; TIGR00544
585034009016	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
585034009017	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
585034009018	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
585034009019	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
585034009020	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
585034009021	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
585034009022	putative active site [active]
585034009023	Ap4A binding site [chemical binding]; other site
585034009024	nudix motif; other site
585034009025	putative metal binding site [ion binding]; other site
585034009026	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
585034009027	putative DNA-binding cleft [nucleotide binding]; other site
585034009028	putative DNA clevage site; other site
585034009029	molecular lever; other site
585034009030	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
585034009031	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
585034009032	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
585034009033	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
585034009034	active site
585034009035	catalytic tetrad [active]
585034009036	lysophospholipid transporter LplT; Provisional; Region: PRK11195
585034009037	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034009038	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
585034009039	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
585034009040	putative acyl-acceptor binding pocket; other site
585034009041	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
585034009042	acyl-activating enzyme (AAE) consensus motif; other site
585034009043	putative AMP binding site [chemical binding]; other site
585034009044	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
585034009045	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585034009046	DNA binding site [nucleotide binding]
585034009047	domain linker motif; other site
585034009048	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
585034009049	dimerization interface (closed form) [polypeptide binding]; other site
585034009050	ligand binding site [chemical binding]; other site
585034009051	diaminopimelate decarboxylase; Provisional; Region: PRK11165
585034009052	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
585034009053	active site
585034009054	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
585034009055	substrate binding site [chemical binding]; other site
585034009056	catalytic residues [active]
585034009057	dimer interface [polypeptide binding]; other site
585034009058	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
585034009059	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034009060	The C-terminal substrate binding domain of LysR, transcriptional regulator for lysine biosynthesis, contains the type 2 periplasmic binding fold; Region: PBP2_LysR; cd08456
585034009061	putative dimerization interface [polypeptide binding]; other site
585034009062	putative racemase; Provisional; Region: PRK10200
585034009063	aspartate racemase; Region: asp_race; TIGR00035
585034009064	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
585034009065	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034009066	putative substrate translocation pore; other site
585034009067	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034009068	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
585034009069	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
585034009070	NADP binding site [chemical binding]; other site
585034009071	homodimer interface [polypeptide binding]; other site
585034009072	active site
585034009073	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
585034009074	putative acyltransferase; Provisional; Region: PRK05790
585034009075	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
585034009076	dimer interface [polypeptide binding]; other site
585034009077	active site
585034009078	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
585034009079	serine transporter; Region: stp; TIGR00814
585034009080	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
585034009081	DNA binding residues [nucleotide binding]
585034009082	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
585034009083	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
585034009084	fragment of Conserved hypothetical protein (partial);Evidence 7 : Gene remnant
585034009085	type III secretion low calcium response chaperone LcrH/SycD; Region: LcrH_SycD; TIGR02552
585034009086	Tetratricopeptide repeat; Region: TPR_3; pfam07720
585034009087	Tetratricopeptide repeat; Region: TPR_3; pfam07720
585034009088	transcriptional regulator; Provisional; Region: PRK11906
585034009089	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
585034009090	DNA binding site [nucleotide binding]
585034009091	Tetratricopeptide repeat; Region: TPR_2; pfam07719
585034009092	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
585034009093	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
585034009094	N-acetyl-D-glucosamine binding site [chemical binding]; other site
585034009095	catalytic residue [active]
585034009096	fragment of conserved hypothetical protein, putative Bacterial regulatory protein LuxR family (part 2);Evidence 7 : Gene remnant
585034009097	fragment of conserved hypothetical protein, putative Bacterial regulatory protein LuxR family (part 1);Evidence 7 : Gene remnant
585034009098	fragment of conserved hypothetical protein (partial);Evidence 7 : Gene remnant
585034009099	type III secretion apparatus protein OrgA/MxiK; Region: OrgA_MxiK; TIGR02555
585034009100	Type III secretory pathway, lipoprotein EscJ [Intracellular trafficking and secretion]; Region: EscJ; COG4669
585034009101	fragment of conserved hypothetical protein, putative type III secretion apparatus protein (partial);Evidence 7 : Gene remnant
585034009102	Type III secretion needle MxiH like; Region: MxiH; cl09641
585034009103	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327; cl12363
585034009104	Type III secretion system protein PrgH-EprH (PrgH); Region: PrgH; pfam09480
585034009105	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585034009106	DNA binding residues [nucleotide binding]
585034009107	dimerization interface [polypeptide binding]; other site
585034009108	InvH outer membrane lipoprotein; Region: InvH; pfam04741
585034009109	fragment of Surface presentation of antigens protein (part 2);Evidence 7 : Gene remnant; Product type m : membrane component
585034009110	fragment of Surface presentation of antigens protein (part 1);Evidence 7 : Gene remnant; Product type m : membrane component
585034009111	type III secretion protein SpaR/YscT/HrcT; Region: fliR_like_III; TIGR01401
585034009112	fragment of surface presentation of antigens protein (partial);Evidence 7 : Gene remnant; Product type pm : putative membrane component
585034009113	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
585034009114	fragment of Type III secretion apparatus protein (partial);Evidence 7 : Gene remnant; Product type t : transporter
585034009115	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
585034009116	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
585034009117	Peptidase family M23; Region: Peptidase_M23; pfam01551
585034009118	xanthine dehydrogenase subunit XdhA; Provisional; Region: PRK09970
585034009119	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
585034009120	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
585034009121	xanthine dehydrogenase subunit XdhB; Provisional; Region: PRK09971
585034009122	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
585034009123	xanthine dehydrogenase subunit XdhC; Provisional; Region: PRK09908
585034009124	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
585034009125	catalytic loop [active]
585034009126	iron binding site [ion binding]; other site
585034009127	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
585034009128	GAF domain; Region: GAF; cl17456
585034009129	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
585034009130	PAS domain; Region: PAS; smart00091
585034009131	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034009132	Walker A motif; other site
585034009133	ATP binding site [chemical binding]; other site
585034009134	Walker B motif; other site
585034009135	arginine finger; other site
585034009136	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
585034009137	aspartate/ornithine carbamoyltransferase family protein; Validated; Region: PRK07200
585034009138	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
585034009139	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
585034009140	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
585034009141	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
585034009142	catalytic residue [active]
585034009143	peptidase; Reviewed; Region: PRK13004
585034009144	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649
585034009145	putative metal binding site [ion binding]; other site
585034009146	putative dimer interface [polypeptide binding]; other site
585034009147	D-hydantoinase; Region: D-hydantoinase; TIGR02033
585034009148	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
585034009149	tetramer interface [polypeptide binding]; other site
585034009150	active site
585034009151	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
585034009152	carbamate kinase; Reviewed; Region: PRK12686
585034009153	putative substrate binding site [chemical binding]; other site
585034009154	homodimer interface [polypeptide binding]; other site
585034009155	nucleotide binding site [chemical binding]; other site
585034009156	nucleotide binding site [chemical binding]; other site
585034009157	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
585034009158	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
585034009159	XdhC Rossmann domain; Region: XdhC_C; pfam13478
585034009160	selenium-dependent molybdenum hydroxylase system protein, YqeB family; Region: matur_yqeB; TIGR03309
585034009161	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
585034009162	probable selenium-dependent hydroxylase accessory protein YqeC; Region: TIGR03172
585034009163	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
585034009164	Ligand binding site; other site
585034009165	metal-binding site
585034009166	putative selenate reductase subunit YgfK; Provisional; Region: PRK09853
585034009167	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
585034009168	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
585034009169	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585034009170	putative selenium metabolism protein SsnA; Region: Se_ssnA; TIGR03314
585034009171	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
585034009172	active site
585034009173	putative substrate binding pocket [chemical binding]; other site
585034009174	probable selenate reductase, FAD-binding subunit; Region: Se_sel_red_FAD; TIGR03312
585034009175	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
585034009176	putative hypoxanthine oxidase; Provisional; Region: PRK09800
585034009177	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
585034009178	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
585034009179	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
585034009180	uracil-xanthine permease; Region: ncs2; TIGR00801
585034009181	guanine deaminase; Provisional; Region: PRK09228
585034009182	Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303
585034009183	active site
585034009184	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
585034009185	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
585034009186	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12809
585034009187	4Fe-4S binding domain; Region: Fer4; pfam00037
585034009188	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
585034009189	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585034009190	xanthine permease; Region: pbuX; TIGR03173
585034009191	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
585034009192	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
585034009193	active site
585034009194	metal binding site [ion binding]; metal-binding site
585034009195	nudix motif; other site
585034009196	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
585034009197	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
585034009198	dimer interface [polypeptide binding]; other site
585034009199	putative anticodon binding site; other site
585034009200	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
585034009201	motif 1; other site
585034009202	active site
585034009203	motif 2; other site
585034009204	motif 3; other site
585034009205	peptide chain release factor 2; Validated; Region: prfB; PRK00578
585034009206	This domain is found in peptide chain release factors; Region: PCRF; smart00937
585034009207	RF-1 domain; Region: RF-1; pfam00472
585034009208	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
585034009209	DHH family; Region: DHH; pfam01368
585034009210	DHHA1 domain; Region: DHHA1; pfam02272
585034009211	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
585034009212	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
585034009213	dimerization domain [polypeptide binding]; other site
585034009214	dimer interface [polypeptide binding]; other site
585034009215	catalytic residues [active]
585034009216	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
585034009217	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
585034009218	active site
585034009219	Int/Topo IB signature motif; other site
585034009220	flavodoxin FldB; Provisional; Region: PRK12359
585034009221	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
585034009222	hypothetical protein; Provisional; Region: PRK10878
585034009223	putative global regulator; Reviewed; Region: PRK09559
585034009224	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
585034009225	hemolysin; Provisional; Region: PRK15087
585034009226	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
585034009227	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
585034009228	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
585034009229	beta-galactosidase; Region: BGL; TIGR03356
585034009230	putative NAD(P)-binding oxidoreductase; Provisional; Region: PRK09730
585034009231	classical (c) SDRs; Region: SDR_c; cd05233
585034009232	NAD(P) binding site [chemical binding]; other site
585034009233	active site
585034009234	glycine dehydrogenase; Provisional; Region: PRK05367
585034009235	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
585034009236	tetramer interface [polypeptide binding]; other site
585034009237	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034009238	catalytic residue [active]
585034009239	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
585034009240	tetramer interface [polypeptide binding]; other site
585034009241	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034009242	catalytic residue [active]
585034009243	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
585034009244	lipoyl attachment site [posttranslational modification]; other site
585034009245	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
585034009246	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
585034009247	oxidoreductase; Provisional; Region: PRK08013
585034009248	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
585034009249	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
585034009250	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
585034009251	proline aminopeptidase P II; Provisional; Region: PRK10879
585034009252	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
585034009253	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
585034009254	active site
585034009255	hypothetical protein; Reviewed; Region: PRK01736
585034009256	Z-ring-associated protein; Provisional; Region: PRK10972
585034009257	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
585034009258	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
585034009259	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
585034009260	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
585034009261	ligand binding site [chemical binding]; other site
585034009262	NAD binding site [chemical binding]; other site
585034009263	tetramer interface [polypeptide binding]; other site
585034009264	catalytic site [active]
585034009265	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
585034009266	L-serine binding site [chemical binding]; other site
585034009267	ACT domain interface; other site
585034009268	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
585034009269	tetramer (dimer of dimers) interface [polypeptide binding]; other site
585034009270	active site
585034009271	dimer interface [polypeptide binding]; other site
585034009272	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
585034009273	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
585034009274	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034009275	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
585034009276	putative dimerization interface [polypeptide binding]; other site
585034009277	methylmalonyl-CoA mutase; Reviewed; Region: PRK09426
585034009278	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Alpha subunit-like subfamily; contains proteins similar to the alpha subunit of Propionbacterium shermanni MCM, as well as human and E. coli MCM. Members of this subfamily contain...; Region: MM_CoA_mutase_alpha_like; cd03679
585034009279	active site
585034009280	substrate binding site [chemical binding]; other site
585034009281	coenzyme B12 binding site [chemical binding]; other site
585034009282	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
585034009283	B12 binding site [chemical binding]; other site
585034009284	cobalt ligand [ion binding]; other site
585034009285	membrane ATPase/protein kinase; Provisional; Region: PRK09435
585034009286	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
585034009287	Walker A; other site
585034009288	methylmalonyl-CoA decarboxylase; Provisional; Region: PRK11423
585034009289	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
585034009290	substrate binding site [chemical binding]; other site
585034009291	oxyanion hole (OAH) forming residues; other site
585034009292	trimer interface [polypeptide binding]; other site
585034009293	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
585034009294	succinate CoA transferase; Region: YgfH_subfam; TIGR03458
585034009295	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
585034009296	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034009297	Transcriptional regulator [Transcription]; Region: LysR; COG0583
585034009298	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
585034009299	dimerization interface [polypeptide binding]; other site
585034009300	Uncharacterized conserved protein [Function unknown]; Region: COG2968
585034009301	oxidative stress defense protein; Provisional; Region: PRK11087
585034009302	arginine exporter protein; Provisional; Region: PRK09304
585034009303	mechanosensitive channel MscS; Provisional; Region: PRK10334
585034009304	Mechanosensitive ion channel; Region: MS_channel; pfam00924
585034009305	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
585034009306	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
585034009307	active site
585034009308	intersubunit interface [polypeptide binding]; other site
585034009309	zinc binding site [ion binding]; other site
585034009310	Na+ binding site [ion binding]; other site
585034009311	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
585034009312	Phosphoglycerate kinase; Region: PGK; pfam00162
585034009313	substrate binding site [chemical binding]; other site
585034009314	hinge regions; other site
585034009315	ADP binding site [chemical binding]; other site
585034009316	catalytic site [active]
585034009317	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
585034009318	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
585034009319	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
585034009320	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
585034009321	trimer interface [polypeptide binding]; other site
585034009322	putative Zn binding site [ion binding]; other site
585034009323	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
585034009324	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
585034009325	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
585034009326	Walker A/P-loop; other site
585034009327	ATP binding site [chemical binding]; other site
585034009328	Q-loop/lid; other site
585034009329	ABC transporter signature motif; other site
585034009330	Walker B; other site
585034009331	D-loop; other site
585034009332	H-loop/switch region; other site
585034009333	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
585034009334	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
585034009335	Walker A/P-loop; other site
585034009336	ATP binding site [chemical binding]; other site
585034009337	Q-loop/lid; other site
585034009338	ABC transporter signature motif; other site
585034009339	Walker B; other site
585034009340	D-loop; other site
585034009341	H-loop/switch region; other site
585034009342	nucleoside triphosphate hydrolase domain-containing protein; Reviewed; Region: PRK09270
585034009343	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
585034009344	active site
585034009345	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
585034009346	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10022
585034009347	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
585034009348	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
585034009349	putative active site [active]
585034009350	fragment of putative dehydrogenase (part 2);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585034009351	fragment of putative dehydrogenase (part 1);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585034009352	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
585034009353	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
585034009354	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
585034009355	active site
585034009356	P-loop; other site
585034009357	phosphorylation site [posttranslational modification]
585034009358	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
585034009359	active site
585034009360	phosphorylation site [posttranslational modification]
585034009361	transketolase; Reviewed; Region: PRK12753
585034009362	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
585034009363	TPP-binding site [chemical binding]; other site
585034009364	dimer interface [polypeptide binding]; other site
585034009365	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
585034009366	PYR/PP interface [polypeptide binding]; other site
585034009367	dimer interface [polypeptide binding]; other site
585034009368	TPP binding site [chemical binding]; other site
585034009369	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
585034009370	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
585034009371	Protein of unknown function (DUF1341); Region: DUF1341; cl06211
585034009372	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
585034009373	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
585034009374	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
585034009375	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
585034009376	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
585034009377	active site
585034009378	phosphorylation site [posttranslational modification]
585034009379	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
585034009380	active pocket/dimerization site; other site
585034009381	active site
585034009382	phosphorylation site [posttranslational modification]
585034009383	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
585034009384	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034009385	Walker A motif; other site
585034009386	ATP binding site [chemical binding]; other site
585034009387	Walker B motif; other site
585034009388	arginine finger; other site
585034009389	Transcriptional antiterminator [Transcription]; Region: COG3933
585034009390	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
585034009391	active site
585034009392	active pocket/dimerization site; other site
585034009393	phosphorylation site [posttranslational modification]
585034009394	PRD domain; Region: PRD; pfam00874
585034009395	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
585034009396	agmatinase; Region: agmatinase; TIGR01230
585034009397	oligomer interface [polypeptide binding]; other site
585034009398	putative active site [active]
585034009399	Mn binding site [ion binding]; other site
585034009400	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
585034009401	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
585034009402	dimer interface [polypeptide binding]; other site
585034009403	active site
585034009404	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
585034009405	catalytic residues [active]
585034009406	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
585034009407	Virulence promoting factor; Region: YqgB; pfam11036
585034009408	Protein of unknown function (DUF2684); Region: DUF2684; pfam10885
585034009409	S-adenosylmethionine synthetase; Validated; Region: PRK05250
585034009410	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
585034009411	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
585034009412	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
585034009413	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
585034009414	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034009415	putative substrate translocation pore; other site
585034009416	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034009417	hypothetical protein; Provisional; Region: PRK04860
585034009418	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
585034009419	DNA-specific endonuclease I; Provisional; Region: PRK15137
585034009420	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
585034009421	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
585034009422	RNA methyltransferase, RsmE family; Region: TIGR00046
585034009423	glutathione synthetase; Provisional; Region: PRK05246
585034009424	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
585034009425	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
585034009426	hypothetical protein; Validated; Region: PRK00228
585034009427	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
585034009428	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
585034009429	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
585034009430	Walker A motif; other site
585034009431	ATP binding site [chemical binding]; other site
585034009432	Walker B motif; other site
585034009433	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
585034009434	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
585034009435	catalytic residue [active]
585034009436	YGGT family; Region: YGGT; pfam02325
585034009437	YGGT family; Region: YGGT; pfam02325
585034009438	hypothetical protein; Validated; Region: PRK05090
585034009439	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
585034009440	active site
585034009441	dimerization interface [polypeptide binding]; other site
585034009442	HemN family oxidoreductase; Provisional; Region: PRK05660
585034009443	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585034009444	FeS/SAM binding site; other site
585034009445	HemN C-terminal domain; Region: HemN_C; pfam06969
585034009446	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
585034009447	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
585034009448	homodimer interface [polypeptide binding]; other site
585034009449	active site
585034009450	hypothetical protein; Provisional; Region: PRK10626
585034009451	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
585034009452	hypothetical protein; Provisional; Region: PRK11702
585034009453	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
585034009454	adenine DNA glycosylase; Provisional; Region: PRK10880
585034009455	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
585034009456	minor groove reading motif; other site
585034009457	helix-hairpin-helix signature motif; other site
585034009458	substrate binding pocket [chemical binding]; other site
585034009459	active site
585034009460	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
585034009461	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
585034009462	DNA binding and oxoG recognition site [nucleotide binding]
585034009463	oxidative damage protection protein; Provisional; Region: PRK05408
585034009464	murein transglycosylase C; Provisional; Region: mltC; PRK11671
585034009465	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
585034009466	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
585034009467	N-acetyl-D-glucosamine binding site [chemical binding]; other site
585034009468	catalytic residue [active]
585034009469	nucleoside transporter; Region: 2A0110; TIGR00889
585034009470	ornithine decarboxylase; Provisional; Region: PRK13578
585034009471	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
585034009472	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
585034009473	homodimer interface [polypeptide binding]; other site
585034009474	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034009475	catalytic residue [active]
585034009476	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
585034009477	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
585034009478	putative general secretion pathway protein YghD; Provisional; Region: PRK09731
585034009479	type II secretion system protein L; Region: typeII_sec_gspL; TIGR01709
585034009480	GspL-like protein; Provisional; Region: PRK09662
585034009481	Type II secretion system (T2SS), protein K; Region: T2SK; pfam03934
585034009482	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
585034009483	type II secretion system protein J; Region: gspJ; TIGR01711
585034009484	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
585034009485	type II secretion system protein I; Region: gspI; TIGR01707
585034009486	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
585034009487	Prokaryotic N-terminal methylation motif; Region: N_methyl; pfam07963
585034009488	Type II transport protein GspH; Region: GspH; pfam12019
585034009489	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
585034009490	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
585034009491	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
585034009492	type II secretion system protein F; Region: GspF; TIGR02120
585034009493	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
585034009494	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
585034009495	type II secretion system protein E; Region: type_II_gspE; TIGR02533
585034009496	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
585034009497	Walker A motif; other site
585034009498	ATP binding site [chemical binding]; other site
585034009499	Walker B motif; other site
585034009500	type II secretion system protein D; Region: type_II_gspD; TIGR02517
585034009501	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
585034009502	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
585034009503	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
585034009504	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
585034009505	putative type II secretion protein GspC; Provisional; Region: PRK09681
585034009506	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
585034009507	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
585034009508	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
585034009509	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
585034009510	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
585034009511	Domain of unknown function (DUF4092); Region: DUF4092; pfam13322
585034009512	Peptidase M60-like family; Region: M60-like; pfam13402
585034009513	glycolate transporter; Provisional; Region: PRK09695
585034009514	L-lactate permease; Region: Lactate_perm; cl00701
585034009515	Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate...; Region: malate_synt_G; cd00728
585034009516	active site
585034009517	hypothetical protein; Provisional; Region: PRK09732
585034009518	glycolate oxidase iron-sulfur subunit; Provisional; Region: glcF; PRK11274
585034009519	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
585034009520	Cysteine-rich domain; Region: CCG; pfam02754
585034009521	Cysteine-rich domain; Region: CCG; pfam02754
585034009522	glycolate oxidase FAD binding subunit; Provisional; Region: glcE; PRK11282
585034009523	FAD binding domain; Region: FAD_binding_4; pfam01565
585034009524	glycolate oxidase subunit GlcD; Provisional; Region: PRK11230
585034009525	FAD binding domain; Region: FAD_binding_4; pfam01565
585034009526	DNA-binding transcriptional regulator GlcC; Provisional; Region: PRK09990
585034009527	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034009528	DNA-binding site [nucleotide binding]; DNA binding site
585034009529	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
585034009530	fragment of Putative AMP-dependent synthetase (part 1);Evidence 7 : Gene remnant; Product type pe : putative enzyme
585034009531	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
585034009532	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
585034009533	NAD(P) binding site [chemical binding]; other site
585034009534	active site
585034009535	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
585034009536	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
585034009537	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
585034009538	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
585034009539	catalytic residue [active]
585034009540	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
585034009541	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
585034009542	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
585034009543	Predicted permeases [General function prediction only]; Region: COG0795
585034009544	Bacterial protein of unknown function (YtfJ_HI0045); Region: YtfJ_HI0045; pfam09695
585034009545	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
585034009546	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
585034009547	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
585034009548	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
585034009549	active site
585034009550	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
585034009551	thymidylate kinase; Region: DTMP_kinase; TIGR00041
585034009552	TMP-binding site; other site
585034009553	ATP-binding site [chemical binding]; other site
585034009554	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
585034009555	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
585034009556	TMP-binding site; other site
585034009557	ATP-binding site [chemical binding]; other site
585034009558	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
585034009559	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
585034009560	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
585034009561	CHAP domain; Region: CHAP; pfam05257
585034009562	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
585034009563	putative S-transferase; Provisional; Region: PRK11752
585034009564	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
585034009565	C-terminal domain interface [polypeptide binding]; other site
585034009566	GSH binding site (G-site) [chemical binding]; other site
585034009567	dimer interface [polypeptide binding]; other site
585034009568	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
585034009569	dimer interface [polypeptide binding]; other site
585034009570	N-terminal domain interface [polypeptide binding]; other site
585034009571	active site
585034009572	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
585034009573	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
585034009574	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
585034009575	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
585034009576	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
585034009577	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
585034009578	putative substrate-binding site; other site
585034009579	nickel binding site [ion binding]; other site
585034009580	hydrogenase 2 large subunit; Provisional; Region: PRK10467
585034009581	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
585034009582	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
585034009583	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
585034009584	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
585034009585	4Fe-4S binding domain; Region: Fer4_6; pfam12837
585034009586	hydrogenase 2 small subunit; Provisional; Region: PRK10468
585034009587	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
585034009588	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
585034009589	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
585034009590	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
585034009591	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
585034009592	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
585034009593	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
585034009594	active site
585034009595	catalytic tetrad [active]
585034009596	hypothetical protein; Provisional; Region: PRK05208
585034009597	oxidoreductase; Provisional; Region: PRK07985
585034009598	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
585034009599	NAD binding site [chemical binding]; other site
585034009600	metal binding site [ion binding]; metal-binding site
585034009601	active site
585034009602	biopolymer transport protein ExbD; Provisional; Region: PRK11267
585034009603	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
585034009604	biopolymer transport protein ExbB; Provisional; Region: PRK10414
585034009605	cystathionine beta-lyase; Provisional; Region: PRK08114
585034009606	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
585034009607	homodimer interface [polypeptide binding]; other site
585034009608	substrate-cofactor binding pocket; other site
585034009609	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034009610	catalytic residue [active]
585034009611	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
585034009612	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
585034009613	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
585034009614	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
585034009615	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034009616	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034009617	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
585034009618	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
585034009619	dimer interface [polypeptide binding]; other site
585034009620	active site
585034009621	metal binding site [ion binding]; metal-binding site
585034009622	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
585034009623	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
585034009624	active site
585034009625	catalytic tetrad [active]
585034009626	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
585034009627	putative outer membrane lipoprotein; Provisional; Region: PRK09973
585034009628	hypothetical protein; Provisional; Region: PRK01254
585034009629	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
585034009630	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
585034009631	FtsI repressor; Provisional; Region: PRK10883
585034009632	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
585034009633	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
585034009634	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
585034009635	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
585034009636	putative acyl-acceptor binding pocket; other site
585034009637	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
585034009638	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
585034009639	CAP-like domain; other site
585034009640	active site
585034009641	primary dimer interface [polypeptide binding]; other site
585034009642	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
585034009643	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
585034009644	TIGR00156 family protein; Region: TIGR00156
585034009645	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
585034009646	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034009647	active site
585034009648	phosphorylation site [posttranslational modification]
585034009649	intermolecular recognition site; other site
585034009650	dimerization interface [polypeptide binding]; other site
585034009651	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585034009652	DNA binding site [nucleotide binding]
585034009653	sensor protein QseC; Provisional; Region: PRK10337
585034009654	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585034009655	dimer interface [polypeptide binding]; other site
585034009656	phosphorylation site [posttranslational modification]
585034009657	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034009658	ATP binding site [chemical binding]; other site
585034009659	Mg2+ binding site [ion binding]; other site
585034009660	G-X-G motif; other site
585034009661	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
585034009662	Uncharacterized conserved protein [Function unknown]; Region: COG1359
585034009663	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
585034009664	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034009665	ATP binding site [chemical binding]; other site
585034009666	Mg2+ binding site [ion binding]; other site
585034009667	G-X-G motif; other site
585034009668	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
585034009669	anchoring element; other site
585034009670	dimer interface [polypeptide binding]; other site
585034009671	ATP binding site [chemical binding]; other site
585034009672	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
585034009673	active site
585034009674	metal binding site [ion binding]; metal-binding site
585034009675	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
585034009676	esterase YqiA; Provisional; Region: PRK11071
585034009677	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
585034009678	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
585034009679	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
585034009680	active site
585034009681	metal binding site [ion binding]; metal-binding site
585034009682	hexamer interface [polypeptide binding]; other site
585034009683	putative dehydrogenase; Provisional; Region: PRK11039
585034009684	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
585034009685	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
585034009686	dimer interface [polypeptide binding]; other site
585034009687	ADP-ribose binding site [chemical binding]; other site
585034009688	active site
585034009689	nudix motif; other site
585034009690	metal binding site [ion binding]; metal-binding site
585034009691	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
585034009692	hypothetical protein; Provisional; Region: PRK11653
585034009693	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
585034009694	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
585034009695	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
585034009696	putative active site [active]
585034009697	metal binding site [ion binding]; metal-binding site
585034009698	zinc transporter ZupT; Provisional; Region: PRK04201
585034009699	ZIP Zinc transporter; Region: Zip; pfam02535
585034009700	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
585034009701	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
585034009702	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
585034009703	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
585034009704	putative fimbrial protein; Provisional; Region: PRK09733
585034009705	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
585034009706	PapC N-terminal domain; Region: PapC_N; pfam13954
585034009707	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585034009708	PapC C-terminal domain; Region: PapC_C; pfam13953
585034009709	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
585034009710	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585034009711	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
585034009712	Fimbrial protein; Region: Fimbrial; pfam00419
585034009713	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
585034009714	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
585034009715	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
585034009716	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
585034009717	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
585034009718	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
585034009719	putative ribose interaction site [chemical binding]; other site
585034009720	putative ADP binding site [chemical binding]; other site
585034009721	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
585034009722	active site
585034009723	nucleotide binding site [chemical binding]; other site
585034009724	HIGH motif; other site
585034009725	KMSKS motif; other site
585034009726	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
585034009727	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
585034009728	metal binding triad; other site
585034009729	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
585034009730	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
585034009731	metal binding triad; other site
585034009732	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
585034009733	Uncharacterized conserved protein [Function unknown]; Region: COG3025
585034009734	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
585034009735	putative active site [active]
585034009736	putative metal binding residues [ion binding]; other site
585034009737	signature motif; other site
585034009738	putative triphosphate binding site [ion binding]; other site
585034009739	CHAD domain; Region: CHAD; pfam05235
585034009740	SH3 domain-containing protein; Provisional; Region: PRK10884
585034009741	Bacterial SH3 domain homologues; Region: SH3b; smart00287
585034009742	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
585034009743	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
585034009744	active site
585034009745	NTP binding site [chemical binding]; other site
585034009746	metal binding triad [ion binding]; metal-binding site
585034009747	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
585034009748	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
585034009749	Zn2+ binding site [ion binding]; other site
585034009750	Mg2+ binding site [ion binding]; other site
585034009751	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
585034009752	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
585034009753	homooctamer interface [polypeptide binding]; other site
585034009754	active site
585034009755	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
585034009756	transcriptional activator TtdR; Provisional; Region: PRK09801
585034009757	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034009758	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
585034009759	putative effector binding pocket; other site
585034009760	putative dimerization interface [polypeptide binding]; other site
585034009761	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
585034009762	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
585034009763	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
585034009764	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
585034009765	transmembrane helices; other site
585034009766	UGMP family protein; Validated; Region: PRK09604
585034009767	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
585034009768	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
585034009769	DNA primase; Validated; Region: dnaG; PRK05667
585034009770	CHC2 zinc finger; Region: zf-CHC2; pfam01807
585034009771	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
585034009772	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
585034009773	active site
585034009774	metal binding site [ion binding]; metal-binding site
585034009775	interdomain interaction site; other site
585034009776	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
585034009777	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
585034009778	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
585034009779	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
585034009780	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
585034009781	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
585034009782	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
585034009783	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
585034009784	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
585034009785	DNA binding residues [nucleotide binding]
585034009786	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
585034009787	active site
585034009788	SUMO-1 interface [polypeptide binding]; other site
585034009789	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
585034009790	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
585034009791	FAD binding pocket [chemical binding]; other site
585034009792	FAD binding motif [chemical binding]; other site
585034009793	phosphate binding motif [ion binding]; other site
585034009794	NAD binding pocket [chemical binding]; other site
585034009795	Predicted transcriptional regulators [Transcription]; Region: COG1695
585034009796	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
585034009797	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585034009798	PAS fold; Region: PAS_3; pfam08447
585034009799	putative active site [active]
585034009800	heme pocket [chemical binding]; other site
585034009801	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
585034009802	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
585034009803	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
585034009804	dimer interface [polypeptide binding]; other site
585034009805	putative CheW interface [polypeptide binding]; other site
585034009806	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
585034009807	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
585034009808	inhibitor-cofactor binding pocket; inhibition site
585034009809	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034009810	catalytic residue [active]
585034009811	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
585034009812	dimer interface [polypeptide binding]; other site
585034009813	putative tRNA-binding site [nucleotide binding]; other site
585034009814	DNA-binding transcriptional repressor EbgR; Provisional; Region: PRK10339
585034009815	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585034009816	DNA binding site [nucleotide binding]
585034009817	domain linker motif; other site
585034009818	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
585034009819	putative dimerization interface [polypeptide binding]; other site
585034009820	putative ligand binding site [chemical binding]; other site
585034009821	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
585034009822	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
585034009823	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
585034009824	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
585034009825	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
585034009826	cryptic beta-D-galactosidase subunit beta; Reviewed; Region: ebgC; PRK10202
585034009827	inner membrane transporter YjeM; Provisional; Region: PRK15238
585034009828	alpha-glucosidase; Provisional; Region: PRK10137
585034009829	Protein of unknown function, DUF608; Region: DUF608; pfam04685
585034009830	Trehalase; Region: Trehalase; cl17346
585034009831	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
585034009832	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
585034009833	active site
585034009834	FMN binding site [chemical binding]; other site
585034009835	2,4-decadienoyl-CoA binding site; other site
585034009836	catalytic residue [active]
585034009837	4Fe-4S cluster binding site [ion binding]; other site
585034009838	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
585034009839	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585034009840	non-specific DNA binding site [nucleotide binding]; other site
585034009841	salt bridge; other site
585034009842	sequence-specific DNA binding site [nucleotide binding]; other site
585034009843	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
585034009844	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034009845	S-adenosylmethionine binding site [chemical binding]; other site
585034009846	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
585034009847	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
585034009848	putative active site [active]
585034009849	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
585034009850	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
585034009851	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
585034009852	serine/threonine transporter SstT; Provisional; Region: PRK13628
585034009853	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
585034009854	Bacterial inner membrane protein; Region: Imp-YgjV; pfam10688
585034009855	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
585034009856	galactarate dehydratase; Region: galactar-dH20; TIGR03248
585034009857	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
585034009858	Glucuronate isomerase; Region: UxaC; pfam02614
585034009859	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
585034009860	D-galactonate transporter; Region: 2A0114; TIGR00893
585034009861	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034009862	putative substrate translocation pore; other site
585034009863	CblD like pilus biogenesis initiator; Region: CblD; cl06460
585034009864	fimbrial outer membrane usher protein TcfC; Provisional; Region: PRK15310
585034009865	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585034009866	CS1 type fimbrial major subunit; Region: Fimbrial_CS1; pfam04449
585034009867	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
585034009868	putative fimbrial protein TcfA; Provisional; Region: PRK15308
585034009869	DNA-binding transcriptional repressor ExuR; Provisional; Region: PRK11523
585034009870	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034009871	DNA-binding site [nucleotide binding]; DNA binding site
585034009872	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
585034009873	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
585034009874	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
585034009875	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
585034009876	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
585034009877	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
585034009878	Predicted membrane protein [Function unknown]; Region: COG5393
585034009879	YqjK-like protein; Region: YqjK; pfam13997
585034009880	Predicted membrane protein [Function unknown]; Region: COG2259
585034009881	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
585034009882	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
585034009883	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
585034009884	putative dimer interface [polypeptide binding]; other site
585034009885	N-terminal domain interface [polypeptide binding]; other site
585034009886	putative substrate binding pocket (H-site) [chemical binding]; other site
585034009887	Predicted membrane protein [Function unknown]; Region: COG3152
585034009888	Protein of unknown function (DUF805); Region: DUF805; pfam05656
585034009889	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034009890	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
585034009891	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
585034009892	dimerization interface [polypeptide binding]; other site
585034009893	Pirin-related protein [General function prediction only]; Region: COG1741
585034009894	Pirin; Region: Pirin; pfam02678
585034009895	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
585034009896	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
585034009897	serine transporter; Region: stp; TIGR00814
585034009898	L-serine dehydratase TdcG; Provisional; Region: PRK15040
585034009899	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
585034009900	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
585034009901	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
585034009902	homotrimer interaction site [polypeptide binding]; other site
585034009903	putative active site [active]
585034009904	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
585034009905	Pyruvate formate lyase 1; Region: PFL1; cd01678
585034009906	coenzyme A binding site [chemical binding]; other site
585034009907	active site
585034009908	catalytic residues [active]
585034009909	glycine loop; other site
585034009910	propionate/acetate kinase; Provisional; Region: PRK12379
585034009911	Acetokinase family; Region: Acetate_kinase; cl17229
585034009912	threonine/serine transporter TdcC; Provisional; Region: PRK13629
585034009913	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
585034009914	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
585034009915	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
585034009916	tetramer interface [polypeptide binding]; other site
585034009917	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034009918	catalytic residue [active]
585034009919	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
585034009920	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034009921	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
585034009922	putative substrate binding pocket [chemical binding]; other site
585034009923	putative dimerization interface [polypeptide binding]; other site
585034009924	DNA-binding transcriptional activator TdcR; Provisional; Region: PRK11424
585034009925	hypothetical protein; Provisional; Region: PRK09716
585034009926	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
585034009927	glycerate kinase I; Provisional; Region: PRK10342
585034009928	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
585034009929	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
585034009930	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
585034009931	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034009932	D-galactonate transporter; Region: 2A0114; TIGR00893
585034009933	putative substrate translocation pore; other site
585034009934	galactarate dehydratase; Region: galactar-dH20; TIGR03248
585034009935	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
585034009936	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
585034009937	putative regulator PrlF; Provisional; Region: PRK09974
585034009938	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
585034009939	Toxin with endonuclease activity YhaV; Region: Toxin_YhaV; pfam11663
585034009940	DNA-binding transcriptional regulator AgaR; Provisional; Region: PRK09802
585034009941	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
585034009942	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585034009943	tagatose 6-phosphate aldolase subunit KbaZ; Provisional; Region: PRK15458
585034009944	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
585034009945	active site
585034009946	phosphorylation site [posttranslational modification]
585034009947	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
585034009948	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
585034009949	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
585034009950	active pocket/dimerization site; other site
585034009951	active site
585034009952	phosphorylation site [posttranslational modification]
585034009953	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
585034009954	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
585034009955	active site
585034009956	dimer interface [polypeptide binding]; other site
585034009957	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
585034009958	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
585034009959	dimer interface [polypeptide binding]; other site
585034009960	active site
585034009961	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
585034009962	putative active site [active]
585034009963	Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cd00453
585034009964	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
585034009965	active site
585034009966	intersubunit interface [polypeptide binding]; other site
585034009967	zinc binding site [ion binding]; other site
585034009968	Na+ binding site [ion binding]; other site
585034009969	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
585034009970	active site
585034009971	phosphorylation site [posttranslational modification]
585034009972	PTS system N-acetylgalactosamine-specific transporter subunit IIC; Provisional; Region: PRK09757
585034009973	PTS system N-acetylgalactosamine-specific transporter subunit IID; Provisional; Region: PRK09855
585034009974	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
585034009975	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
585034009976	active site
585034009977	trimer interface [polypeptide binding]; other site
585034009978	allosteric site; other site
585034009979	active site lid [active]
585034009980	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
585034009981	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
585034009982	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585034009983	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
585034009984	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
585034009985	PapC N-terminal domain; Region: PapC_N; pfam13954
585034009986	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585034009987	PapC C-terminal domain; Region: PapC_C; pfam13953
585034009988	Fimbrial protein; Region: Fimbrial; pfam00419
585034009989	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
585034009990	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
585034009991	putative SAM binding site [chemical binding]; other site
585034009992	putative homodimer interface [polypeptide binding]; other site
585034009993	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
585034009994	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
585034009995	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
585034009996	putative ligand binding site [chemical binding]; other site
585034009997	TIGR00252 family protein; Region: TIGR00252
585034009998	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
585034009999	dimer interface [polypeptide binding]; other site
585034010000	active site
585034010001	outer membrane lipoprotein; Provisional; Region: PRK11023
585034010002	BON domain; Region: BON; pfam04972
585034010003	BON domain; Region: BON; pfam04972
585034010004	Predicted permease; Region: DUF318; pfam03773
585034010005	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
585034010006	NADH(P)-binding; Region: NAD_binding_10; pfam13460
585034010007	NAD binding site [chemical binding]; other site
585034010008	active site
585034010009	intracellular protease, PfpI family; Region: PfpI; TIGR01382
585034010010	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
585034010011	proposed catalytic triad [active]
585034010012	conserved cys residue [active]
585034010013	hypothetical protein; Provisional; Region: PRK03467
585034010014	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
585034010015	GIY-YIG motif/motif A; other site
585034010016	putative active site [active]
585034010017	putative metal binding site [ion binding]; other site
585034010018	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
585034010019	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585034010020	Coenzyme A binding pocket [chemical binding]; other site
585034010021	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
585034010022	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
585034010023	Peptidase family U32; Region: Peptidase_U32; pfam01136
585034010024	putative protease; Provisional; Region: PRK15447
585034010025	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
585034010026	hypothetical protein; Provisional; Region: PRK10508
585034010027	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
585034010028	tryptophan permease; Provisional; Region: PRK10483
585034010029	aromatic amino acid transport protein; Region: araaP; TIGR00837
585034010030	ATP-dependent RNA helicase DeaD; Provisional; Region: PRK11634
585034010031	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
585034010032	ATP binding site [chemical binding]; other site
585034010033	Mg++ binding site [ion binding]; other site
585034010034	motif III; other site
585034010035	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585034010036	nucleotide binding region [chemical binding]; other site
585034010037	ATP-binding site [chemical binding]; other site
585034010038	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
585034010039	putative RNA binding site [nucleotide binding]; other site
585034010040	lipoprotein NlpI; Provisional; Region: PRK11189
585034010041	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585034010042	binding surface
585034010043	TPR motif; other site
585034010044	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
585034010045	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
585034010046	RNase E interface [polypeptide binding]; other site
585034010047	trimer interface [polypeptide binding]; other site
585034010048	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
585034010049	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
585034010050	RNase E interface [polypeptide binding]; other site
585034010051	trimer interface [polypeptide binding]; other site
585034010052	active site
585034010053	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
585034010054	putative nucleic acid binding region [nucleotide binding]; other site
585034010055	G-X-X-G motif; other site
585034010056	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
585034010057	RNA binding site [nucleotide binding]; other site
585034010058	domain interface; other site
585034010059	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
585034010060	16S/18S rRNA binding site [nucleotide binding]; other site
585034010061	S13e-L30e interaction site [polypeptide binding]; other site
585034010062	25S rRNA binding site [nucleotide binding]; other site
585034010063	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
585034010064	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
585034010065	RNA binding site [nucleotide binding]; other site
585034010066	active site
585034010067	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
585034010068	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
585034010069	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
585034010070	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
585034010071	translation initiation factor IF-2; Region: IF-2; TIGR00487
585034010072	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
585034010073	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
585034010074	G1 box; other site
585034010075	putative GEF interaction site [polypeptide binding]; other site
585034010076	GTP/Mg2+ binding site [chemical binding]; other site
585034010077	Switch I region; other site
585034010078	G2 box; other site
585034010079	G3 box; other site
585034010080	Switch II region; other site
585034010081	G4 box; other site
585034010082	G5 box; other site
585034010083	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
585034010084	Translation-initiation factor 2; Region: IF-2; pfam11987
585034010085	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
585034010086	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
585034010087	NusA N-terminal domain; Region: NusA_N; pfam08529
585034010088	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
585034010089	RNA binding site [nucleotide binding]; other site
585034010090	homodimer interface [polypeptide binding]; other site
585034010091	NusA-like KH domain; Region: KH_5; pfam13184
585034010092	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
585034010093	G-X-X-G motif; other site
585034010094	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
585034010095	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
585034010096	ribosome maturation protein RimP; Reviewed; Region: PRK00092
585034010097	Sm and related proteins; Region: Sm_like; cl00259
585034010098	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
585034010099	putative oligomer interface [polypeptide binding]; other site
585034010100	putative RNA binding site [nucleotide binding]; other site
585034010101	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
585034010102	ANP binding site [chemical binding]; other site
585034010103	Substrate Binding Site II [chemical binding]; other site
585034010104	Substrate Binding Site I [chemical binding]; other site
585034010105	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
585034010106	Sulfatase; Region: Sulfatase; pfam00884
585034010107	Preprotein translocase SecG subunit; Region: SecG; pfam03840
585034010108	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
585034010109	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
585034010110	active site
585034010111	substrate binding site [chemical binding]; other site
585034010112	metal binding site [ion binding]; metal-binding site
585034010113	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
585034010114	dihydropteroate synthase; Region: DHPS; TIGR01496
585034010115	substrate binding pocket [chemical binding]; other site
585034010116	dimer interface [polypeptide binding]; other site
585034010117	inhibitor binding site; inhibition site
585034010118	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
585034010119	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034010120	Walker A motif; other site
585034010121	ATP binding site [chemical binding]; other site
585034010122	Walker B motif; other site
585034010123	arginine finger; other site
585034010124	Peptidase family M41; Region: Peptidase_M41; pfam01434
585034010125	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
585034010126	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034010127	S-adenosylmethionine binding site [chemical binding]; other site
585034010128	RNA-binding protein YhbY; Provisional; Region: PRK10343
585034010129	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
585034010130	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
585034010131	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
585034010132	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
585034010133	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
585034010134	GTPase CgtA; Reviewed; Region: obgE; PRK12298
585034010135	GTP1/OBG; Region: GTP1_OBG; pfam01018
585034010136	Obg GTPase; Region: Obg; cd01898
585034010137	G1 box; other site
585034010138	GTP/Mg2+ binding site [chemical binding]; other site
585034010139	Switch I region; other site
585034010140	G2 box; other site
585034010141	G3 box; other site
585034010142	Switch II region; other site
585034010143	G4 box; other site
585034010144	G5 box; other site
585034010145	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
585034010146	EamA-like transporter family; Region: EamA; pfam00892
585034010147	EamA-like transporter family; Region: EamA; pfam00892
585034010148	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
585034010149	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
585034010150	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
585034010151	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
585034010152	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
585034010153	substrate binding pocket [chemical binding]; other site
585034010154	chain length determination region; other site
585034010155	substrate-Mg2+ binding site; other site
585034010156	catalytic residues [active]
585034010157	aspartate-rich region 1; other site
585034010158	active site lid residues [active]
585034010159	aspartate-rich region 2; other site
585034010160	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
585034010161	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
585034010162	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
585034010163	hinge; other site
585034010164	active site
585034010165	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
585034010166	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
585034010167	anti sigma factor interaction site; other site
585034010168	regulatory phosphorylation site [posttranslational modification]; other site
585034010169	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
585034010170	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
585034010171	mce related protein; Region: MCE; pfam02470
585034010172	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
585034010173	conserved hypothetical integral membrane protein; Region: TIGR00056
585034010174	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
585034010175	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
585034010176	Walker A/P-loop; other site
585034010177	ATP binding site [chemical binding]; other site
585034010178	Q-loop/lid; other site
585034010179	ABC transporter signature motif; other site
585034010180	Walker B; other site
585034010181	D-loop; other site
585034010182	H-loop/switch region; other site
585034010183	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
585034010184	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
585034010185	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
585034010186	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
585034010187	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
585034010188	putative active site [active]
585034010189	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
585034010190	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
585034010191	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
585034010192	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
585034010193	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
585034010194	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
585034010195	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
585034010196	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
585034010197	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
585034010198	Walker A/P-loop; other site
585034010199	ATP binding site [chemical binding]; other site
585034010200	Q-loop/lid; other site
585034010201	ABC transporter signature motif; other site
585034010202	Walker B; other site
585034010203	D-loop; other site
585034010204	H-loop/switch region; other site
585034010205	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
585034010206	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
585034010207	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
585034010208	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
585034010209	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
585034010210	30S subunit binding site; other site
585034010211	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
585034010212	active site
585034010213	phosphorylation site [posttranslational modification]
585034010214	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
585034010215	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
585034010216	dimerization domain swap beta strand [polypeptide binding]; other site
585034010217	regulatory protein interface [polypeptide binding]; other site
585034010218	active site
585034010219	regulatory phosphorylation site [posttranslational modification]; other site
585034010220	hypothetical protein; Provisional; Region: PRK10345
585034010221	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
585034010222	Transglycosylase; Region: Transgly; cl17702
585034010223	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
585034010224	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
585034010225	conserved cys residue [active]
585034010226	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
585034010227	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585034010228	putative active site [active]
585034010229	heme pocket [chemical binding]; other site
585034010230	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585034010231	dimer interface [polypeptide binding]; other site
585034010232	phosphorylation site [posttranslational modification]
585034010233	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034010234	ATP binding site [chemical binding]; other site
585034010235	Mg2+ binding site [ion binding]; other site
585034010236	G-X-G motif; other site
585034010237	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034010238	active site
585034010239	phosphorylation site [posttranslational modification]
585034010240	intermolecular recognition site; other site
585034010241	dimerization interface [polypeptide binding]; other site
585034010242	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
585034010243	putative binding surface; other site
585034010244	active site
585034010245	radical SAM protein, TIGR01212 family; Region: TIGR01212
585034010246	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585034010247	FeS/SAM binding site; other site
585034010248	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
585034010249	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
585034010250	active site
585034010251	dimer interface [polypeptide binding]; other site
585034010252	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
585034010253	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
585034010254	active site
585034010255	FMN binding site [chemical binding]; other site
585034010256	substrate binding site [chemical binding]; other site
585034010257	3Fe-4S cluster binding site [ion binding]; other site
585034010258	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
585034010259	domain interface; other site
585034010260	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
585034010261	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
585034010262	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585034010263	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
585034010264	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
585034010265	uncharacterized protein, YhcH/YjgK/YiaL family; Region: TIGR00022
585034010266	N-acetylmannosamine kinase; Provisional; Region: PRK05082
585034010267	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
585034010268	nucleotide binding site [chemical binding]; other site
585034010269	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
585034010270	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
585034010271	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
585034010272	putative active site cavity [active]
585034010273	putative sialic acid transporter; Provisional; Region: PRK03893
585034010274	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034010275	putative substrate translocation pore; other site
585034010276	N-acetylneuraminate lyase; Region: nanA; TIGR00683
585034010277	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
585034010278	inhibitor site; inhibition site
585034010279	active site
585034010280	dimer interface [polypeptide binding]; other site
585034010281	catalytic residue [active]
585034010282	transcriptional regulator NanR; Provisional; Region: PRK03837
585034010283	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034010284	DNA-binding site [nucleotide binding]; DNA binding site
585034010285	FCD domain; Region: FCD; pfam07729
585034010286	putative cryptic C4-dicarboxylate transporter DcuD; Provisional; Region: PRK09804
585034010287	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
585034010288	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
585034010289	stringent starvation protein A; Provisional; Region: sspA; PRK09481
585034010290	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
585034010291	C-terminal domain interface [polypeptide binding]; other site
585034010292	putative GSH binding site (G-site) [chemical binding]; other site
585034010293	dimer interface [polypeptide binding]; other site
585034010294	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
585034010295	dimer interface [polypeptide binding]; other site
585034010296	N-terminal domain interface [polypeptide binding]; other site
585034010297	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
585034010298	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
585034010299	23S rRNA interface [nucleotide binding]; other site
585034010300	L3 interface [polypeptide binding]; other site
585034010301	Predicted ATPase [General function prediction only]; Region: COG1485
585034010302	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
585034010303	hypothetical protein; Provisional; Region: PRK11677
585034010304	serine endoprotease; Provisional; Region: PRK10139
585034010305	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
585034010306	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
585034010307	protein binding site [polypeptide binding]; other site
585034010308	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
585034010309	serine endoprotease; Provisional; Region: PRK10898
585034010310	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
585034010311	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
585034010312	malate dehydrogenase; Provisional; Region: PRK05086
585034010313	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
585034010314	NAD binding site [chemical binding]; other site
585034010315	dimerization interface [polypeptide binding]; other site
585034010316	Substrate binding site [chemical binding]; other site
585034010317	arginine repressor; Provisional; Region: PRK05066
585034010318	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
585034010319	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
585034010320	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
585034010321	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
585034010322	RNAase interaction site [polypeptide binding]; other site
585034010323	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
585034010324	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
585034010325	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
585034010326	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585034010327	HlyD family secretion protein; Region: HlyD_3; pfam13437
585034010328	efflux system membrane protein; Provisional; Region: PRK11594
585034010329	transcriptional regulator; Provisional; Region: PRK10632
585034010330	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034010331	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
585034010332	putative effector binding pocket; other site
585034010333	dimerization interface [polypeptide binding]; other site
585034010334	protease TldD; Provisional; Region: tldD; PRK10735
585034010335	hypothetical protein; Provisional; Region: PRK10899
585034010336	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
585034010337	ribonuclease G; Provisional; Region: PRK11712
585034010338	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
585034010339	homodimer interface [polypeptide binding]; other site
585034010340	oligonucleotide binding site [chemical binding]; other site
585034010341	Maf-like protein; Region: Maf; pfam02545
585034010342	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
585034010343	active site
585034010344	dimer interface [polypeptide binding]; other site
585034010345	rod shape-determining protein MreD; Provisional; Region: PRK11060
585034010346	rod shape-determining protein MreC; Region: mreC; TIGR00219
585034010347	rod shape-determining protein MreC; Region: MreC; pfam04085
585034010348	rod shape-determining protein MreB; Provisional; Region: PRK13927
585034010349	MreB and similar proteins; Region: MreB_like; cd10225
585034010350	nucleotide binding site [chemical binding]; other site
585034010351	Mg binding site [ion binding]; other site
585034010352	putative protofilament interaction site [polypeptide binding]; other site
585034010353	RodZ interaction site [polypeptide binding]; other site
585034010354	regulatory protein CsrD; Provisional; Region: PRK11059
585034010355	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585034010356	metal binding site [ion binding]; metal-binding site
585034010357	active site
585034010358	I-site; other site
585034010359	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585034010360	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
585034010361	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
585034010362	NADP binding site [chemical binding]; other site
585034010363	dimer interface [polypeptide binding]; other site
585034010364	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
585034010365	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
585034010366	carboxyltransferase (CT) interaction site; other site
585034010367	biotinylation site [posttranslational modification]; other site
585034010368	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
585034010369	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
585034010370	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
585034010371	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
585034010372	hypothetical protein; Provisional; Region: PRK10633
585034010373	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
585034010374	Na binding site [ion binding]; other site
585034010375	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
585034010376	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
585034010377	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
585034010378	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
585034010379	FMN binding site [chemical binding]; other site
585034010380	active site
585034010381	catalytic residues [active]
585034010382	substrate binding site [chemical binding]; other site
585034010383	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
585034010384	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
585034010385	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
585034010386	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034010387	DNA methylase; Region: N6_N4_Mtase; pfam01555
585034010388	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
585034010389	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
585034010390	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585034010391	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
585034010392	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
585034010393	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585034010394	HlyD family secretion protein; Region: HlyD_3; pfam13437
585034010395	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
585034010396	Protein export membrane protein; Region: SecD_SecF; cl14618
585034010397	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
585034010398	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
585034010399	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585034010400	substrate binding pocket [chemical binding]; other site
585034010401	membrane-bound complex binding site; other site
585034010402	hinge residues; other site
585034010403	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: BatB; COG4597
585034010404	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034010405	conserved gate region; other site
585034010406	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034010407	dimer interface [polypeptide binding]; other site
585034010408	conserved gate region; other site
585034010409	putative PBP binding loops; other site
585034010410	ABC-ATPase subunit interface; other site
585034010411	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
585034010412	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034010413	dimer interface [polypeptide binding]; other site
585034010414	conserved gate region; other site
585034010415	putative PBP binding loops; other site
585034010416	ABC-ATPase subunit interface; other site
585034010417	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
585034010418	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
585034010419	Walker A/P-loop; other site
585034010420	ATP binding site [chemical binding]; other site
585034010421	Q-loop/lid; other site
585034010422	ABC transporter signature motif; other site
585034010423	Walker B; other site
585034010424	D-loop; other site
585034010425	H-loop/switch region; other site
585034010426	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
585034010427	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
585034010428	trimer interface [polypeptide binding]; other site
585034010429	putative metal binding site [ion binding]; other site
585034010430	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
585034010431	shikimate 5-dehydrogenase; Region: aroE; TIGR00507
585034010432	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
585034010433	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
585034010434	shikimate binding site; other site
585034010435	NAD(P) binding site [chemical binding]; other site
585034010436	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
585034010437	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
585034010438	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
585034010439	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
585034010440	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
585034010441	hypothetical protein; Validated; Region: PRK03430
585034010442	hypothetical protein; Provisional; Region: PRK10736
585034010443	DNA protecting protein DprA; Region: dprA; TIGR00732
585034010444	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
585034010445	active site
585034010446	catalytic residues [active]
585034010447	metal binding site [ion binding]; metal-binding site
585034010448	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
585034010449	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
585034010450	putative active site [active]
585034010451	substrate binding site [chemical binding]; other site
585034010452	putative cosubstrate binding site; other site
585034010453	catalytic site [active]
585034010454	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
585034010455	substrate binding site [chemical binding]; other site
585034010456	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
585034010457	putative RNA binding site [nucleotide binding]; other site
585034010458	16S rRNA methyltransferase B; Provisional; Region: PRK10901
585034010459	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034010460	S-adenosylmethionine binding site [chemical binding]; other site
585034010461	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
585034010462	TrkA-N domain; Region: TrkA_N; pfam02254
585034010463	TrkA-C domain; Region: TrkA_C; pfam02080
585034010464	TrkA-N domain; Region: TrkA_N; pfam02254
585034010465	TrkA-C domain; Region: TrkA_C; pfam02080
585034010466	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
585034010467	Large-conductance mechanosensitive channel, MscL; Region: MscL; pfam01741
585034010468	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
585034010469	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
585034010470	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
585034010471	DNA binding residues [nucleotide binding]
585034010472	dimer interface [polypeptide binding]; other site
585034010473	metal binding site [ion binding]; metal-binding site
585034010474	hypothetical protein; Provisional; Region: PRK10203
585034010475	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
585034010476	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
585034010477	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
585034010478	alphaNTD homodimer interface [polypeptide binding]; other site
585034010479	alphaNTD - beta interaction site [polypeptide binding]; other site
585034010480	alphaNTD - beta' interaction site [polypeptide binding]; other site
585034010481	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
585034010482	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
585034010483	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
585034010484	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
585034010485	RNA binding surface [nucleotide binding]; other site
585034010486	30S ribosomal protein S11; Validated; Region: PRK05309
585034010487	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
585034010488	30S ribosomal protein S13; Region: bact_S13; TIGR03631
585034010489	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
585034010490	SecY translocase; Region: SecY; pfam00344
585034010491	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
585034010492	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
585034010493	23S rRNA binding site [nucleotide binding]; other site
585034010494	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
585034010495	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
585034010496	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
585034010497	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
585034010498	23S rRNA interface [nucleotide binding]; other site
585034010499	5S rRNA interface [nucleotide binding]; other site
585034010500	L27 interface [polypeptide binding]; other site
585034010501	L5 interface [polypeptide binding]; other site
585034010502	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
585034010503	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
585034010504	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
585034010505	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
585034010506	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
585034010507	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
585034010508	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
585034010509	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
585034010510	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
585034010511	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
585034010512	RNA binding site [nucleotide binding]; other site
585034010513	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
585034010514	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
585034010515	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
585034010516	23S rRNA interface [nucleotide binding]; other site
585034010517	putative translocon interaction site; other site
585034010518	signal recognition particle (SRP54) interaction site; other site
585034010519	L23 interface [polypeptide binding]; other site
585034010520	trigger factor interaction site; other site
585034010521	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
585034010522	23S rRNA interface [nucleotide binding]; other site
585034010523	5S rRNA interface [nucleotide binding]; other site
585034010524	putative antibiotic binding site [chemical binding]; other site
585034010525	L25 interface [polypeptide binding]; other site
585034010526	L27 interface [polypeptide binding]; other site
585034010527	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
585034010528	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
585034010529	G-X-X-G motif; other site
585034010530	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
585034010531	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
585034010532	protein-rRNA interface [nucleotide binding]; other site
585034010533	putative translocon binding site; other site
585034010534	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
585034010535	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
585034010536	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
585034010537	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
585034010538	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
585034010539	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
585034010540	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
585034010541	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
585034010542	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
585034010543	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
585034010544	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
585034010545	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
585034010546	heme binding site [chemical binding]; other site
585034010547	ferroxidase pore; other site
585034010548	ferroxidase diiron center [ion binding]; other site
585034010549	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
585034010550	elongation factor Tu; Reviewed; Region: PRK00049
585034010551	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
585034010552	G1 box; other site
585034010553	GEF interaction site [polypeptide binding]; other site
585034010554	GTP/Mg2+ binding site [chemical binding]; other site
585034010555	Switch I region; other site
585034010556	G2 box; other site
585034010557	G3 box; other site
585034010558	Switch II region; other site
585034010559	G4 box; other site
585034010560	G5 box; other site
585034010561	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
585034010562	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
585034010563	Antibiotic Binding Site [chemical binding]; other site
585034010564	elongation factor G; Reviewed; Region: PRK00007
585034010565	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
585034010566	G1 box; other site
585034010567	putative GEF interaction site [polypeptide binding]; other site
585034010568	GTP/Mg2+ binding site [chemical binding]; other site
585034010569	Switch I region; other site
585034010570	G2 box; other site
585034010571	G3 box; other site
585034010572	Switch II region; other site
585034010573	G4 box; other site
585034010574	G5 box; other site
585034010575	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
585034010576	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
585034010577	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
585034010578	30S ribosomal protein S7; Validated; Region: PRK05302
585034010579	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
585034010580	S17 interaction site [polypeptide binding]; other site
585034010581	S8 interaction site; other site
585034010582	16S rRNA interaction site [nucleotide binding]; other site
585034010583	streptomycin interaction site [chemical binding]; other site
585034010584	23S rRNA interaction site [nucleotide binding]; other site
585034010585	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
585034010586	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
585034010587	sulfur relay protein TusC; Validated; Region: PRK00211
585034010588	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
585034010589	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
585034010590	YheO-like PAS domain; Region: PAS_6; pfam08348
585034010591	HTH domain; Region: HTH_22; pfam13309
585034010592	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
585034010593	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
585034010594	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
585034010595	phi X174 lysis protein; Provisional; Region: PRK02793
585034010596	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
585034010597	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
585034010598	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
585034010599	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
585034010600	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
585034010601	TrkA-N domain; Region: TrkA_N; pfam02254
585034010602	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
585034010603	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
585034010604	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585034010605	Walker A/P-loop; other site
585034010606	ATP binding site [chemical binding]; other site
585034010607	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
585034010608	ABC transporter signature motif; other site
585034010609	Walker B; other site
585034010610	D-loop; other site
585034010611	ABC transporter; Region: ABC_tran_2; pfam12848
585034010612	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
585034010613	putative hydrolase; Provisional; Region: PRK10985
585034010614	hypothetical protein; Provisional; Region: PRK04966
585034010615	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
585034010616	active site
585034010617	hypothetical protein; Provisional; Region: PRK10738
585034010618	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
585034010619	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
585034010620	ligand binding site [chemical binding]; other site
585034010621	flexible hinge region; other site
585034010622	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
585034010623	putative switch regulator; other site
585034010624	non-specific DNA interactions [nucleotide binding]; other site
585034010625	DNA binding site [nucleotide binding]
585034010626	sequence specific DNA binding site [nucleotide binding]; other site
585034010627	putative cAMP binding site [chemical binding]; other site
585034010628	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
585034010629	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
585034010630	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
585034010631	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
585034010632	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
585034010633	inhibitor-cofactor binding pocket; inhibition site
585034010634	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034010635	catalytic residue [active]
585034010636	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
585034010637	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
585034010638	glutamine binding [chemical binding]; other site
585034010639	catalytic triad [active]
585034010640	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
585034010641	cell filamentation protein Fic; Provisional; Region: PRK10347
585034010642	hypothetical protein; Provisional; Region: PRK10204
585034010643	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
585034010644	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
585034010645	substrate binding site [chemical binding]; other site
585034010646	putative transporter; Provisional; Region: PRK03699
585034010647	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034010648	putative substrate translocation pore; other site
585034010649	nitrite reductase subunit NirD; Provisional; Region: PRK14989
585034010650	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585034010651	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
585034010652	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
585034010653	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
585034010654	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
585034010655	nitrite transporter NirC; Provisional; Region: PRK11562
585034010656	siroheme synthase; Provisional; Region: cysG; PRK10637
585034010657	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
585034010658	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
585034010659	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
585034010660	active site
585034010661	SAM binding site [chemical binding]; other site
585034010662	homodimer interface [polypeptide binding]; other site
585034010663	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
585034010664	putative fructoselysine transporter; Provisional; Region: frlA; PRK11357
585034010665	hypothetical protein; Provisional; Region: PHA02764
585034010666	fructoselysine-6-P-deglycase; Provisional; Region: frlB; PRK11382
585034010667	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
585034010668	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
585034010669	dimer interface [polypeptide binding]; other site
585034010670	active site
585034010671	fructoselysine 3-epimerase; Provisional; Region: PRK09856
585034010672	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
585034010673	AP (apurinic/apyrimidinic) site pocket; other site
585034010674	DNA interaction; other site
585034010675	Metal-binding active site; metal-binding site
585034010676	Fructoselysine kinase-like.  Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the...; Region: Fructoselysine_kinase_like; cd01940
585034010677	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
585034010678	substrate binding site [chemical binding]; other site
585034010679	ATP binding site [chemical binding]; other site
585034010680	DNA-binding transcriptional regulator FrlR; Provisional; Region: PRK11402
585034010681	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034010682	DNA-binding site [nucleotide binding]; DNA binding site
585034010683	UTRA domain; Region: UTRA; pfam07702
585034010684	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
585034010685	DNA topoisomerase III, bacteria and conjugative plasmid; Region: topB; TIGR01056
585034010686	Protein of unknown function; Region: YhfT; pfam10797
585034010687	Protein of unknown function DUF2620; Region: DUF2620; pfam10941
585034010688	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
585034010689	active site
585034010690	substrate binding pocket [chemical binding]; other site
585034010691	homodimer interaction site [polypeptide binding]; other site
585034010692	putative mutase; Provisional; Region: PRK12383
585034010693	Phosphopentomutase [Carbohydrate transport and metabolism]; Region: DeoB; COG1015
585034010694	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme yhfX; Region: PLPDE_III_yhfX_like; cd06811
585034010695	dimer interface [polypeptide binding]; other site
585034010696	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
585034010697	active site
585034010698	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
585034010699	substrate binding site [chemical binding]; other site
585034010700	catalytic residue [active]
585034010701	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
585034010702	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
585034010703	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
585034010704	active site
585034010705	HIGH motif; other site
585034010706	dimer interface [polypeptide binding]; other site
585034010707	KMSKS motif; other site
585034010708	phosphoglycolate phosphatase; Provisional; Region: PRK13222
585034010709	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
585034010710	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034010711	motif II; other site
585034010712	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
585034010713	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
585034010714	substrate binding site [chemical binding]; other site
585034010715	hexamer interface [polypeptide binding]; other site
585034010716	metal binding site [ion binding]; metal-binding site
585034010717	DNA adenine methylase; Provisional; Region: PRK10904
585034010718	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DamX; COG3266
585034010719	cell division protein DamX; Validated; Region: PRK10905
585034010720	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
585034010721	active site
585034010722	dimer interface [polypeptide binding]; other site
585034010723	metal binding site [ion binding]; metal-binding site
585034010724	shikimate kinase; Reviewed; Region: aroK; PRK00131
585034010725	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
585034010726	ADP binding site [chemical binding]; other site
585034010727	magnesium binding site [ion binding]; other site
585034010728	putative shikimate binding site; other site
585034010729	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
585034010730	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
585034010731	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
585034010732	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
585034010733	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
585034010734	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
585034010735	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
585034010736	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
585034010737	Transglycosylase; Region: Transgly; pfam00912
585034010738	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
585034010739	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
585034010740	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
585034010741	ADP-ribose binding site [chemical binding]; other site
585034010742	dimer interface [polypeptide binding]; other site
585034010743	active site
585034010744	nudix motif; other site
585034010745	metal binding site [ion binding]; metal-binding site
585034010746	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
585034010747	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
585034010748	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034010749	motif II; other site
585034010750	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
585034010751	RNA binding surface [nucleotide binding]; other site
585034010752	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
585034010753	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
585034010754	dimerization interface [polypeptide binding]; other site
585034010755	domain crossover interface; other site
585034010756	redox-dependent activation switch; other site
585034010757	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
585034010758	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
585034010759	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
585034010760	active site
585034010761	substrate-binding site [chemical binding]; other site
585034010762	metal-binding site [ion binding]
585034010763	ATP binding site [chemical binding]; other site
585034010764	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
585034010765	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585034010766	non-specific DNA binding site [nucleotide binding]; other site
585034010767	salt bridge; other site
585034010768	sequence-specific DNA binding site [nucleotide binding]; other site
585034010769	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
585034010770	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585034010771	dimerization interface [polypeptide binding]; other site
585034010772	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585034010773	dimer interface [polypeptide binding]; other site
585034010774	phosphorylation site [posttranslational modification]
585034010775	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034010776	ATP binding site [chemical binding]; other site
585034010777	G-X-G motif; other site
585034010778	osmolarity response regulator; Provisional; Region: ompR; PRK09468
585034010779	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034010780	active site
585034010781	phosphorylation site [posttranslational modification]
585034010782	intermolecular recognition site; other site
585034010783	dimerization interface [polypeptide binding]; other site
585034010784	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585034010785	DNA binding site [nucleotide binding]
585034010786	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
585034010787	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
585034010788	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
585034010789	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
585034010790	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
585034010791	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
585034010792	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
585034010793	RNA binding site [nucleotide binding]; other site
585034010794	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
585034010795	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
585034010796	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
585034010797	G1 box; other site
585034010798	GTP/Mg2+ binding site [chemical binding]; other site
585034010799	Switch I region; other site
585034010800	G2 box; other site
585034010801	G3 box; other site
585034010802	Switch II region; other site
585034010803	G4 box; other site
585034010804	G5 box; other site
585034010805	Nucleoside recognition; Region: Gate; pfam07670
585034010806	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
585034010807	Nucleoside recognition; Region: Gate; pfam07670
585034010808	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
585034010809	putative transposase; Provisional; Region: PRK09857
585034010810	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
585034010811	carboxylesterase BioH; Provisional; Region: PRK10349
585034010812	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
585034010813	DNA utilization protein GntX; Provisional; Region: PRK11595
585034010814	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
585034010815	active site
585034010816	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
585034010817	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
585034010818	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
585034010819	high-affinity gluconate transporter; Provisional; Region: PRK14984
585034010820	gluconate transporter; Region: gntP; TIGR00791
585034010821	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
585034010822	4-alpha-glucanotransferase; Region: malQ; TIGR00217
585034010823	maltodextrin phosphorylase; Provisional; Region: PRK14985
585034010824	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
585034010825	homodimer interface [polypeptide binding]; other site
585034010826	active site pocket [active]
585034010827	transcriptional regulator MalT; Provisional; Region: PRK04841
585034010828	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585034010829	DNA binding residues [nucleotide binding]
585034010830	RNA 3'-terminal-phosphate cyclase; Provisional; Region: PRK04204
585034010831	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288
585034010832	putative active site [active]
585034010833	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
585034010834	hypothetical protein; Reviewed; Region: PRK09588
585034010835	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
585034010836	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
585034010837	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034010838	Walker A motif; other site
585034010839	ATP binding site [chemical binding]; other site
585034010840	Walker B motif; other site
585034010841	arginine finger; other site
585034010842	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
585034010843	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
585034010844	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585034010845	intramembrane serine protease GlpG; Provisional; Region: PRK10907
585034010846	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
585034010847	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
585034010848	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
585034010849	active site residue [active]
585034010850	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
585034010851	hypothetical protein; Provisional; Region: PRK09781; cl08057
585034010852	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
585034010853	glycogen phosphorylase; Provisional; Region: PRK14986
585034010854	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
585034010855	homodimer interface [polypeptide binding]; other site
585034010856	active site pocket [active]
585034010857	glycogen synthase; Provisional; Region: glgA; PRK00654
585034010858	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
585034010859	ADP-binding pocket [chemical binding]; other site
585034010860	homodimer interface [polypeptide binding]; other site
585034010861	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
585034010862	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
585034010863	ligand binding site; other site
585034010864	oligomer interface; other site
585034010865	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
585034010866	sulfate 1 binding site; other site
585034010867	glycogen debranching enzyme; Provisional; Region: PRK03705
585034010868	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
585034010869	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
585034010870	active site
585034010871	catalytic site [active]
585034010872	glycogen branching enzyme; Provisional; Region: PRK05402
585034010873	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
585034010874	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
585034010875	active site
585034010876	catalytic site [active]
585034010877	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
585034010878	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
585034010879	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
585034010880	putative antibiotic transporter; Provisional; Region: PRK10739
585034010881	low affinity gluconate transporter; Provisional; Region: PRK10472
585034010882	gluconate transporter; Region: gntP; TIGR00791
585034010883	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
585034010884	ATP-binding site [chemical binding]; other site
585034010885	Gluconate-6-phosphate binding site [chemical binding]; other site
585034010886	Shikimate kinase; Region: SKI; pfam01202
585034010887	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
585034010888	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585034010889	DNA binding site [nucleotide binding]
585034010890	domain linker motif; other site
585034010891	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
585034010892	putative ligand binding site [chemical binding]; other site
585034010893	putative dimerization interface [polypeptide binding]; other site
585034010894	Pirin-related protein [General function prediction only]; Region: COG1741
585034010895	Pirin; Region: Pirin; pfam02678
585034010896	putative oxidoreductase; Provisional; Region: PRK10206
585034010897	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
585034010898	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
585034010899	putative acetyltransferase YhhY; Provisional; Region: PRK10140
585034010900	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585034010901	Coenzyme A binding pocket [chemical binding]; other site
585034010902	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
585034010903	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
585034010904	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
585034010905	hypothetical protein; Provisional; Region: PRK10350
585034010906	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
585034010907	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
585034010908	putative active site [active]
585034010909	catalytic site [active]
585034010910	putative metal binding site [ion binding]; other site
585034010911	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
585034010912	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
585034010913	Walker A/P-loop; other site
585034010914	ATP binding site [chemical binding]; other site
585034010915	Q-loop/lid; other site
585034010916	ABC transporter signature motif; other site
585034010917	Walker B; other site
585034010918	D-loop; other site
585034010919	H-loop/switch region; other site
585034010920	TOBE domain; Region: TOBE_2; pfam08402
585034010921	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
585034010922	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034010923	dimer interface [polypeptide binding]; other site
585034010924	conserved gate region; other site
585034010925	putative PBP binding loops; other site
585034010926	ABC-ATPase subunit interface; other site
585034010927	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
585034010928	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034010929	dimer interface [polypeptide binding]; other site
585034010930	conserved gate region; other site
585034010931	putative PBP binding loops; other site
585034010932	ABC-ATPase subunit interface; other site
585034010933	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
585034010934	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
585034010935	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
585034010936	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
585034010937	Walker A/P-loop; other site
585034010938	ATP binding site [chemical binding]; other site
585034010939	Q-loop/lid; other site
585034010940	ABC transporter signature motif; other site
585034010941	Walker B; other site
585034010942	D-loop; other site
585034010943	H-loop/switch region; other site
585034010944	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
585034010945	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
585034010946	Walker A/P-loop; other site
585034010947	ATP binding site [chemical binding]; other site
585034010948	Q-loop/lid; other site
585034010949	ABC transporter signature motif; other site
585034010950	Walker B; other site
585034010951	D-loop; other site
585034010952	H-loop/switch region; other site
585034010953	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
585034010954	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
585034010955	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
585034010956	TM-ABC transporter signature motif; other site
585034010957	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585034010958	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
585034010959	TM-ABC transporter signature motif; other site
585034010960	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
585034010961	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
585034010962	dimerization interface [polypeptide binding]; other site
585034010963	ligand binding site [chemical binding]; other site
585034010964	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
585034010965	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
585034010966	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
585034010967	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
585034010968	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
585034010969	dimerization interface [polypeptide binding]; other site
585034010970	ligand binding site [chemical binding]; other site
585034010971	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
585034010972	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
585034010973	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
585034010974	DNA binding residues [nucleotide binding]
585034010975	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
585034010976	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
585034010977	cell division protein FtsE; Provisional; Region: PRK10908
585034010978	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585034010979	Walker A/P-loop; other site
585034010980	ATP binding site [chemical binding]; other site
585034010981	Q-loop/lid; other site
585034010982	ABC transporter signature motif; other site
585034010983	Walker B; other site
585034010984	D-loop; other site
585034010985	H-loop/switch region; other site
585034010986	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
585034010987	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
585034010988	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
585034010989	P loop; other site
585034010990	GTP binding site [chemical binding]; other site
585034010991	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
585034010992	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034010993	S-adenosylmethionine binding site [chemical binding]; other site
585034010994	hypothetical protein; Provisional; Region: PRK10910
585034010995	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
585034010996	Predicted membrane protein [Function unknown]; Region: COG3714
585034010997	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
585034010998	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
585034010999	metal-binding site [ion binding]
585034011000	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
585034011001	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
585034011002	CPxP  motif; other site
585034011003	hypothetical protein; Provisional; Region: PRK11212
585034011004	hypothetical protein; Provisional; Region: PRK11615
585034011005	major facilitator superfamily transporter; Provisional; Region: PRK05122
585034011006	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034011007	putative substrate translocation pore; other site
585034011008	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
585034011009	Domain of unknown function DUF20; Region: UPF0118; pfam01594
585034011010	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
585034011011	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
585034011012	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
585034011013	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
585034011014	substrate binding site [chemical binding]; other site
585034011015	nickel transporter permease NikB; Provisional; Region: PRK10352
585034011016	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034011017	dimer interface [polypeptide binding]; other site
585034011018	conserved gate region; other site
585034011019	putative PBP binding loops; other site
585034011020	ABC-ATPase subunit interface; other site
585034011021	nickel transporter permease NikC; Provisional; Region: nikC; PRK10417
585034011022	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034011023	dimer interface [polypeptide binding]; other site
585034011024	conserved gate region; other site
585034011025	putative PBP binding loops; other site
585034011026	ABC-ATPase subunit interface; other site
585034011027	nickel transporter ATP-binding protein NikD; Provisional; Region: nikD; PRK10418
585034011028	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585034011029	Walker A/P-loop; other site
585034011030	ATP binding site [chemical binding]; other site
585034011031	Q-loop/lid; other site
585034011032	ABC transporter signature motif; other site
585034011033	Walker B; other site
585034011034	D-loop; other site
585034011035	H-loop/switch region; other site
585034011036	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
585034011037	nickel transporter ATP-binding protein NikE; Provisional; Region: nikE; PRK10419
585034011038	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585034011039	Walker A/P-loop; other site
585034011040	ATP binding site [chemical binding]; other site
585034011041	Q-loop/lid; other site
585034011042	ABC transporter signature motif; other site
585034011043	Walker B; other site
585034011044	D-loop; other site
585034011045	H-loop/switch region; other site
585034011046	nickel responsive regulator; Provisional; Region: PRK02967
585034011047	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
585034011048	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
585034011049	HicB family; Region: HicB; pfam05534
585034011050	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
585034011051	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
585034011052	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
585034011053	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
585034011054	Walker A/P-loop; other site
585034011055	ATP binding site [chemical binding]; other site
585034011056	Q-loop/lid; other site
585034011057	ABC transporter signature motif; other site
585034011058	Walker B; other site
585034011059	D-loop; other site
585034011060	H-loop/switch region; other site
585034011061	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
585034011062	Walker A/P-loop; other site
585034011063	ATP binding site [chemical binding]; other site
585034011064	Q-loop/lid; other site
585034011065	ABC transporter signature motif; other site
585034011066	Walker B; other site
585034011067	D-loop; other site
585034011068	H-loop/switch region; other site
585034011069	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
585034011070	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
585034011071	HlyD family secretion protein; Region: HlyD; pfam00529
585034011072	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585034011073	HlyD family secretion protein; Region: HlyD_3; pfam13437
585034011074	Domain of unknown function (DUF4049); Region: DUF4049; pfam13258
585034011075	Domain of unknown function (DUF4049); Region: DUF4049; pfam13258
585034011076	Protein of unknown function (DUF2776); Region: DUF2776; pfam10951
585034011077	Predicted flavoproteins [General function prediction only]; Region: COG2081
585034011078	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
585034011079	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
585034011080	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
585034011081	universal stress protein UspB; Provisional; Region: PRK04960
585034011082	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
585034011083	Ligand Binding Site [chemical binding]; other site
585034011084	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
585034011085	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034011086	POT family; Region: PTR2; pfam00854
585034011087	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034011088	S-adenosylmethionine binding site [chemical binding]; other site
585034011089	oligopeptidase A; Provisional; Region: PRK10911
585034011090	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
585034011091	active site
585034011092	Zn binding site [ion binding]; other site
585034011093	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
585034011094	glutathione reductase; Validated; Region: PRK06116
585034011095	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
585034011096	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585034011097	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
585034011098	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
585034011099	dimerization interface [polypeptide binding]; other site
585034011100	putative DNA binding site [nucleotide binding]; other site
585034011101	putative Zn2+ binding site [ion binding]; other site
585034011102	arsenical pump membrane protein; Provisional; Region: PRK15445
585034011103	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
585034011104	transmembrane helices; other site
585034011105	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
585034011106	ArsC family; Region: ArsC; pfam03960
585034011107	catalytic residues [active]
585034011108	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
585034011109	dimerization interface [polypeptide binding]; other site
585034011110	putative DNA binding site [nucleotide binding]; other site
585034011111	putative Zn2+ binding site [ion binding]; other site
585034011112	Predicted permeases [General function prediction only]; Region: COG0701
585034011113	outer membrane lipoprotein, Slp family; Region: slp; TIGR00752
585034011114	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
585034011115	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585034011116	DNA binding residues [nucleotide binding]
585034011117	dimerization interface [polypeptide binding]; other site
585034011118	putative Mg(2+) transport ATPase; Provisional; Region: PRK09977
585034011119	MgtC family; Region: MgtC; pfam02308
585034011120	acid-resistance protein; Provisional; Region: hdeB; PRK11566
585034011121	acid-resistance protein; Provisional; Region: PRK10208
585034011122	acid-resistance membrane protein; Provisional; Region: PRK10209
585034011123	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
585034011124	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
585034011125	pyruvate kinase; Provisional; Region: PRK05826
585034011126	multidrug efflux system protein MdtE; Provisional; Region: PRK09859
585034011127	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585034011128	HlyD family secretion protein; Region: HlyD_3; pfam13437
585034011129	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
585034011130	Protein export membrane protein; Region: SecD_SecF; cl14618
585034011131	transcriptional regulator YdeO; Provisional; Region: PRK09940
585034011132	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034011133	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
585034011134	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034011135	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
585034011136	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034011137	catalytic residue [active]
585034011138	Haem-binding domain; Region: Haem_bd; pfam14376
585034011139	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
585034011140	trehalase; Provisional; Region: treF; PRK13270
585034011141	Trehalase; Region: Trehalase; pfam01204
585034011142	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
585034011143	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585034011144	DNA binding residues [nucleotide binding]
585034011145	dimerization interface [polypeptide binding]; other site
585034011146	Transcriptional regulator [Transcription]; Region: LysR; COG0583
585034011147	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034011148	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
585034011149	putative effector binding pocket; other site
585034011150	putative dimerization interface [polypeptide binding]; other site
585034011151	inner membrane protein YhjD; Region: TIGR00766
585034011152	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034011153	metabolite-proton symporter; Region: 2A0106; TIGR00883
585034011154	putative substrate translocation pore; other site
585034011155	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
585034011156	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
585034011157	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585034011158	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
585034011159	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
585034011160	substrate binding site [chemical binding]; other site
585034011161	ATP binding site [chemical binding]; other site
585034011162	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
585034011163	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
585034011164	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
585034011165	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
585034011166	putative diguanylate cyclase; Provisional; Region: PRK13561
585034011167	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
585034011168	metal binding site [ion binding]; metal-binding site
585034011169	active site
585034011170	I-site; other site
585034011171	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585034011172	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
585034011173	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585034011174	binding surface
585034011175	TPR motif; other site
585034011176	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585034011177	binding surface
585034011178	TPR motif; other site
585034011179	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
585034011180	endo-1,4-D-glucanase; Provisional; Region: PRK11097
585034011181	cellulose synthase regulator protein; Provisional; Region: PRK11114
585034011182	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
585034011183	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
585034011184	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
585034011185	DXD motif; other site
585034011186	PilZ domain; Region: PilZ; pfam07238
585034011187	cell division protein; Provisional; Region: PRK10037
585034011188	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
585034011189	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
585034011190	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
585034011191	celllulose biosynthesis operon protein BcsF/YhjT; Region: cellullose_BcsF; TIGR03493
585034011192	Protein of unknown function (DUF3260); Region: DUF3260; pfam11658
585034011193	fragment of toxic polypeptide, small (partial);Evidence 7 : Gene remnant; Product type f : factor
585034011194	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
585034011195	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
585034011196	fragment of toxic polypeptide, small (partial);Evidence 7 : Gene remnant; Product type f : factor
585034011197	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
585034011198	serine transporter; Region: stp; TIGR00814
585034011199	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
585034011200	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585034011201	Walker A/P-loop; other site
585034011202	ATP binding site [chemical binding]; other site
585034011203	Q-loop/lid; other site
585034011204	ABC transporter signature motif; other site
585034011205	Walker B; other site
585034011206	D-loop; other site
585034011207	H-loop/switch region; other site
585034011208	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
585034011209	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
585034011210	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585034011211	Walker A/P-loop; other site
585034011212	ATP binding site [chemical binding]; other site
585034011213	Q-loop/lid; other site
585034011214	ABC transporter signature motif; other site
585034011215	Walker B; other site
585034011216	D-loop; other site
585034011217	H-loop/switch region; other site
585034011218	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
585034011219	dipeptide transporter; Provisional; Region: PRK10913
585034011220	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
585034011221	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034011222	dimer interface [polypeptide binding]; other site
585034011223	conserved gate region; other site
585034011224	putative PBP binding loops; other site
585034011225	ABC-ATPase subunit interface; other site
585034011226	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
585034011227	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034011228	dimer interface [polypeptide binding]; other site
585034011229	conserved gate region; other site
585034011230	putative PBP binding loops; other site
585034011231	ABC-ATPase subunit interface; other site
585034011232	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
585034011233	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
585034011234	peptide binding site [polypeptide binding]; other site
585034011235	phosphoethanolamine transferase; Provisional; Region: PRK11560
585034011236	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
585034011237	Sulfatase; Region: Sulfatase; pfam00884
585034011238	long polar fimbrial protein LpfE; Provisional; Region: PRK15205
585034011239	long polar fimbrial protein LpfD; Provisional; Region: PRK15206
585034011240	long polar fimbrial outer membrane usher protein LpfC; Provisional; Region: PRK15207
585034011241	PapC N-terminal domain; Region: PapC_N; pfam13954
585034011242	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585034011243	PapC C-terminal domain; Region: PapC_C; pfam13953
585034011244	long polar fimbrial chaperone LpfB; Provisional; Region: PRK15208
585034011245	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585034011246	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
585034011247	long polar fimbrial protein LpfA; Provisional; Region: PRK15209
585034011248	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
585034011249	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034011250	putative substrate translocation pore; other site
585034011251	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
585034011252	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
585034011253	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
585034011254	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585034011255	Coenzyme A binding pocket [chemical binding]; other site
585034011256	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
585034011257	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
585034011258	molybdopterin cofactor binding site [chemical binding]; other site
585034011259	substrate binding site [chemical binding]; other site
585034011260	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
585034011261	molybdopterin cofactor binding site; other site
585034011262	putative outer membrane lipoprotein; Provisional; Region: PRK10510
585034011263	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
585034011264	ligand binding site [chemical binding]; other site
585034011265	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
585034011266	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
585034011267	dimerization interface [polypeptide binding]; other site
585034011268	ligand binding site [chemical binding]; other site
585034011269	NADP binding site [chemical binding]; other site
585034011270	catalytic site [active]
585034011271	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
585034011272	Predicted transcriptional regulator [Transcription]; Region: COG2944
585034011273	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585034011274	non-specific DNA binding site [nucleotide binding]; other site
585034011275	salt bridge; other site
585034011276	sequence-specific DNA binding site [nucleotide binding]; other site
585034011277	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
585034011278	DNA-binding site [nucleotide binding]; DNA binding site
585034011279	RNA-binding motif; other site
585034011280	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
585034011281	DALR anticodon binding domain; Region: DALR_1; pfam05746
585034011282	anticodon binding site; other site
585034011283	tRNA binding surface [nucleotide binding]; other site
585034011284	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
585034011285	dimer interface [polypeptide binding]; other site
585034011286	motif 1; other site
585034011287	active site
585034011288	motif 2; other site
585034011289	motif 3; other site
585034011290	YsaB-like lipoprotein; Region: YsaB; pfam13983
585034011291	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
585034011292	Acyltransferase family; Region: Acyl_transf_3; pfam01757
585034011293	hypothetical protein; Provisional; Region: PRK11383
585034011294	yiaA/B two helix domain; Region: YiaAB; pfam05360
585034011295	yiaA/B two helix domain; Region: YiaAB; pfam05360
585034011296	hypothetical protein; Provisional; Region: PRK11403
585034011297	yiaA/B two helix domain; Region: YiaAB; pfam05360
585034011298	xylulokinase; Provisional; Region: PRK15027
585034011299	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
585034011300	N- and C-terminal domain interface [polypeptide binding]; other site
585034011301	active site
585034011302	MgATP binding site [chemical binding]; other site
585034011303	catalytic site [active]
585034011304	metal binding site [ion binding]; metal-binding site
585034011305	xylulose binding site [chemical binding]; other site
585034011306	homodimer interface [polypeptide binding]; other site
585034011307	xylose isomerase; Provisional; Region: PRK05474
585034011308	xylose isomerase; Region: xylose_isom_A; TIGR02630
585034011309	D-xylose transporter subunit XylF; Provisional; Region: xylF; PRK10355
585034011310	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
585034011311	putative ligand binding site [chemical binding]; other site
585034011312	xylose transporter ATP-binding subunit; Provisional; Region: PRK13549
585034011313	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
585034011314	Walker A/P-loop; other site
585034011315	ATP binding site [chemical binding]; other site
585034011316	Q-loop/lid; other site
585034011317	ABC transporter signature motif; other site
585034011318	Walker B; other site
585034011319	D-loop; other site
585034011320	H-loop/switch region; other site
585034011321	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
585034011322	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585034011323	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585034011324	TM-ABC transporter signature motif; other site
585034011325	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
585034011326	putative dimerization interface [polypeptide binding]; other site
585034011327	Transcriptional regulators [Transcription]; Region: PurR; COG1609
585034011328	putative ligand binding site [chemical binding]; other site
585034011329	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034011330	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
585034011331	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034011332	hypothetical protein; Provisional; Region: PRK10356
585034011333	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
585034011334	alpha-amylase; Reviewed; Region: malS; PRK09505
585034011335	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
585034011336	active site
585034011337	catalytic site [active]
585034011338	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
585034011339	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585034011340	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034011341	homodimer interface [polypeptide binding]; other site
585034011342	catalytic residue [active]
585034011343	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
585034011344	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
585034011345	Transcriptional regulator [Transcription]; Region: IclR; COG1414
585034011346	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
585034011347	Bacterial transcriptional regulator; Region: IclR; pfam01614
585034011348	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
585034011349	uncharacterized protein, YhcH/YjgK/YiaL family; Region: TIGR00022
585034011350	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
585034011351	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
585034011352	DctM-like transporters; Region: DctM; pfam06808
585034011353	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
585034011354	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
585034011355	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
585034011356	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
585034011357	putative N- and C-terminal domain interface [polypeptide binding]; other site
585034011358	putative active site [active]
585034011359	MgATP binding site [chemical binding]; other site
585034011360	catalytic site [active]
585034011361	metal binding site [ion binding]; metal-binding site
585034011362	putative xylulose binding site [chemical binding]; other site
585034011363	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
585034011364	active site
585034011365	dimer interface [polypeptide binding]; other site
585034011366	magnesium binding site [ion binding]; other site
585034011367	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
585034011368	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
585034011369	AP (apurinic/apyrimidinic) site pocket; other site
585034011370	DNA interaction; other site
585034011371	Metal-binding active site; metal-binding site
585034011372	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
585034011373	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
585034011374	intersubunit interface [polypeptide binding]; other site
585034011375	active site
585034011376	Zn2+ binding site [ion binding]; other site
585034011377	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
585034011378	Transcriptional regulator [Transcription]; Region: LysR; COG0583
585034011379	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034011380	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
585034011381	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
585034011382	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585034011383	HlyD family secretion protein; Region: HlyD_3; pfam13437
585034011384	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
585034011385	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
585034011386	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
585034011387	NAD(P) binding site [chemical binding]; other site
585034011388	catalytic residues [active]
585034011389	putative alcohol dehydrogenase; Provisional; Region: PRK09860
585034011390	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
585034011391	dimer interface [polypeptide binding]; other site
585034011392	active site
585034011393	metal binding site [ion binding]; metal-binding site
585034011394	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
585034011395	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
585034011396	G1 box; other site
585034011397	putative GEF interaction site [polypeptide binding]; other site
585034011398	GTP/Mg2+ binding site [chemical binding]; other site
585034011399	Switch I region; other site
585034011400	G2 box; other site
585034011401	G3 box; other site
585034011402	Switch II region; other site
585034011403	G4 box; other site
585034011404	G5 box; other site
585034011405	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
585034011406	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
585034011407	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
585034011408	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
585034011409	selenocysteine synthase; Provisional; Region: PRK04311
585034011410	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
585034011411	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
585034011412	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
585034011413	catalytic residue [active]
585034011414	putative glutathione S-transferase; Provisional; Region: PRK10357
585034011415	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
585034011416	putative C-terminal domain interface [polypeptide binding]; other site
585034011417	putative GSH binding site (G-site) [chemical binding]; other site
585034011418	putative dimer interface [polypeptide binding]; other site
585034011419	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
585034011420	dimer interface [polypeptide binding]; other site
585034011421	N-terminal domain interface [polypeptide binding]; other site
585034011422	putative substrate binding pocket (H-site) [chemical binding]; other site
585034011423	fragment of rhsC element core protein RshC (partial);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585034011424	fragment of conserved rhs-like protein of unknown function (part 2);Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin
585034011425	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
585034011426	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
585034011427	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585034011428	HlyD family secretion protein; Region: HlyD_3; pfam13437
585034011429	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
585034011430	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
585034011431	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
585034011432	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
585034011433	active site
585034011434	P-loop; other site
585034011435	phosphorylation site [posttranslational modification]
585034011436	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
585034011437	active site
585034011438	phosphorylation site [posttranslational modification]
585034011439	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
585034011440	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
585034011441	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
585034011442	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
585034011443	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
585034011444	hypothetical protein; Provisional; Region: PRK11020
585034011445	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
585034011446	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
585034011447	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
585034011448	trimer interface [polypeptide binding]; other site
585034011449	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
585034011450	trimer interface [polypeptide binding]; other site
585034011451	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
585034011452	Haemagglutinin; Region: HIM; pfam05662
585034011453	Haemagglutinin; Region: HIM; pfam05662
585034011454	YadA-like C-terminal region; Region: YadA; pfam03895
585034011455	L-lactate permease; Provisional; Region: PRK10420
585034011456	glycolate transporter; Provisional; Region: PRK09695
585034011457	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
585034011458	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034011459	DNA-binding site [nucleotide binding]; DNA binding site
585034011460	FCD domain; Region: FCD; pfam07729
585034011461	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
585034011462	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
585034011463	phosphate binding site [ion binding]; other site
585034011464	putative rRNA methylase; Provisional; Region: PRK10358
585034011465	serine acetyltransferase; Provisional; Region: cysE; PRK11132
585034011466	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
585034011467	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
585034011468	trimer interface [polypeptide binding]; other site
585034011469	active site
585034011470	substrate binding site [chemical binding]; other site
585034011471	CoA binding site [chemical binding]; other site
585034011472	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
585034011473	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
585034011474	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
585034011475	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
585034011476	SecA binding site; other site
585034011477	Preprotein binding site; other site
585034011478	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
585034011479	GSH binding site [chemical binding]; other site
585034011480	catalytic residues [active]
585034011481	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
585034011482	active site residue [active]
585034011483	phosphoglyceromutase; Provisional; Region: PRK05434
585034011484	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
585034011485	AmiB activator; Provisional; Region: PRK11637
585034011486	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
585034011487	Peptidase family M23; Region: Peptidase_M23; pfam01551
585034011488	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
585034011489	NodB motif; other site
585034011490	putative active site [active]
585034011491	putative catalytic site [active]
585034011492	Zn binding site [ion binding]; other site
585034011493	putative glycosyl transferase; Provisional; Region: PRK10073
585034011494	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
585034011495	active site
585034011496	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
585034011497	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
585034011498	NAD(P) binding site [chemical binding]; other site
585034011499	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
585034011500	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
585034011501	substrate-cofactor binding pocket; other site
585034011502	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034011503	catalytic residue [active]
585034011504	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
585034011505	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
585034011506	NADP binding site [chemical binding]; other site
585034011507	homopentamer interface [polypeptide binding]; other site
585034011508	substrate binding site [chemical binding]; other site
585034011509	active site
585034011510	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
585034011511	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
585034011512	putative active site [active]
585034011513	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
585034011514	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
585034011515	putative active site [active]
585034011516	O-Antigen ligase; Region: Wzy_C; pfam04932
585034011517	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
585034011518	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
585034011519	active site
585034011520	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
585034011521	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
585034011522	Ligand binding site; other site
585034011523	metal-binding site
585034011524	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
585034011525	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; pfam06176
585034011526	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
585034011527	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
585034011528	Ligand binding site; other site
585034011529	metal-binding site
585034011530	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
585034011531	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
585034011532	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
585034011533	Ligand binding site; other site
585034011534	metal-binding site
585034011535	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
585034011536	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
585034011537	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
585034011538	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
585034011539	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
585034011540	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
585034011541	putative active site [active]
585034011542	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
585034011543	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
585034011544	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
585034011545	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
585034011546	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
585034011547	active site
585034011548	(T/H)XGH motif; other site
585034011549	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
585034011550	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
585034011551	DNA binding site [nucleotide binding]
585034011552	catalytic residue [active]
585034011553	H2TH interface [polypeptide binding]; other site
585034011554	putative catalytic residues [active]
585034011555	turnover-facilitating residue; other site
585034011556	intercalation triad [nucleotide binding]; other site
585034011557	8OG recognition residue [nucleotide binding]; other site
585034011558	putative reading head residues; other site
585034011559	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
585034011560	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
585034011561	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
585034011562	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
585034011563	hypothetical protein; Reviewed; Region: PRK00024
585034011564	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
585034011565	MPN+ (JAMM) motif; other site
585034011566	Zinc-binding site [ion binding]; other site
585034011567	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
585034011568	Flavoprotein; Region: Flavoprotein; pfam02441
585034011569	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
585034011570	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
585034011571	trimer interface [polypeptide binding]; other site
585034011572	active site
585034011573	division inhibitor protein; Provisional; Region: slmA; PRK09480
585034011574	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585034011575	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
585034011576	active site
585034011577	ribonuclease PH; Reviewed; Region: rph; PRK00173
585034011578	Ribonuclease PH; Region: RNase_PH_bact; cd11362
585034011579	hexamer interface [polypeptide binding]; other site
585034011580	active site
585034011581	hypothetical protein; Provisional; Region: PRK11820
585034011582	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
585034011583	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
585034011584	BRO family, N-terminal domain; Region: Bro-N; cl10591
585034011585	Predicted membrane protein [Function unknown]; Region: COG2860
585034011586	UPF0126 domain; Region: UPF0126; pfam03458
585034011587	UPF0126 domain; Region: UPF0126; pfam03458
585034011588	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
585034011589	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
585034011590	nucleotide binding pocket [chemical binding]; other site
585034011591	K-X-D-G motif; other site
585034011592	catalytic site [active]
585034011593	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
585034011594	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
585034011595	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
585034011596	catalytic site [active]
585034011597	G-X2-G-X-G-K; other site
585034011598	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
585034011599	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
585034011600	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
585034011601	Zn2+ binding site [ion binding]; other site
585034011602	Mg2+ binding site [ion binding]; other site
585034011603	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
585034011604	synthetase active site [active]
585034011605	NTP binding site [chemical binding]; other site
585034011606	metal binding site [ion binding]; metal-binding site
585034011607	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
585034011608	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
585034011609	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
585034011610	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
585034011611	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
585034011612	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
585034011613	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
585034011614	generic binding surface II; other site
585034011615	ssDNA binding site; other site
585034011616	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585034011617	ATP binding site [chemical binding]; other site
585034011618	putative Mg++ binding site [ion binding]; other site
585034011619	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585034011620	nucleotide binding region [chemical binding]; other site
585034011621	ATP-binding site [chemical binding]; other site
585034011622	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
585034011623	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
585034011624	AsmA family; Region: AsmA; pfam05170
585034011625	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
585034011626	putative alpha-glucosidase; Provisional; Region: PRK10658
585034011627	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
585034011628	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
585034011629	active site
585034011630	homotrimer interface [polypeptide binding]; other site
585034011631	catalytic site [active]
585034011632	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
585034011633	putative transporter; Provisional; Region: PRK11462
585034011634	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
585034011635	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
585034011636	sugar efflux transporter; Region: 2A0120; TIGR00899
585034011637	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034011638	putative substrate translocation pore; other site
585034011639	EamA-like transporter family; Region: EamA; pfam00892
585034011640	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
585034011641	EamA-like transporter family; Region: EamA; pfam00892
585034011642	cytoplasmic membrane lipoprotein-28; Provisional; Region: PRK09861
585034011643	lipoprotein, YaeC family; Region: TIGR00363
585034011644	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
585034011645	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
585034011646	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034011647	putative substrate translocation pore; other site
585034011648	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
585034011649	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
585034011650	cryptic adenine deaminase; Provisional; Region: PRK10027
585034011651	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
585034011652	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
585034011653	active site
585034011654	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
585034011655	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
585034011656	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034011657	putative substrate translocation pore; other site
585034011658	regulatory protein UhpC; Provisional; Region: PRK11663
585034011659	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034011660	putative substrate translocation pore; other site
585034011661	sensory histidine kinase UhpB; Provisional; Region: PRK11644
585034011662	MASE1; Region: MASE1; pfam05231
585034011663	Histidine kinase; Region: HisKA_3; pfam07730
585034011664	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
585034011665	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034011666	active site
585034011667	phosphorylation site [posttranslational modification]
585034011668	intermolecular recognition site; other site
585034011669	dimerization interface [polypeptide binding]; other site
585034011670	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585034011671	DNA binding residues [nucleotide binding]
585034011672	dimerization interface [polypeptide binding]; other site
585034011673	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
585034011674	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
585034011675	putative valine binding site [chemical binding]; other site
585034011676	dimer interface [polypeptide binding]; other site
585034011677	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
585034011678	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
585034011679	PYR/PP interface [polypeptide binding]; other site
585034011680	dimer interface [polypeptide binding]; other site
585034011681	TPP binding site [chemical binding]; other site
585034011682	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
585034011683	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
585034011684	TPP-binding site [chemical binding]; other site
585034011685	dimer interface [polypeptide binding]; other site
585034011686	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
585034011687	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034011688	putative substrate translocation pore; other site
585034011689	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
585034011690	Domain of unknown function (DUF202); Region: DUF202; pfam02656
585034011691	Predicted membrane protein [Function unknown]; Region: COG2149
585034011692	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
585034011693	Sulfatase; Region: Sulfatase; pfam00884
585034011694	putative transporter; Provisional; Region: PRK10484
585034011695	uncharacterized SLC5 subfamily, Escherichia coli YidK-like; solute binding domain; Region: SLC5sbd_YidK; cd10328
585034011696	Na binding site [ion binding]; other site
585034011697	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
585034011698	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034011699	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
585034011700	fragment of 6-phospho-glucosidase (part 2);Evidence 7 : Gene remnant; Product type e : enzyme
585034011701	fragment of 6-phospho-glucosidase (part 1);Evidence 7 : Gene remnant; Product type e : enzyme
585034011702	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
585034011703	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
585034011704	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
585034011705	active site turn [active]
585034011706	phosphorylation site [posttranslational modification]
585034011707	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
585034011708	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034011709	DNA-binding site [nucleotide binding]; DNA binding site
585034011710	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
585034011711	putative transporter; Validated; Region: PRK03818
585034011712	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
585034011713	TrkA-C domain; Region: TrkA_C; pfam02080
585034011714	TrkA-C domain; Region: TrkA_C; pfam02080
585034011715	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
585034011716	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
585034011717	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
585034011718	putative dimer interface [polypeptide binding]; other site
585034011719	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
585034011720	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
585034011721	putative dimer interface [polypeptide binding]; other site
585034011722	hypothetical protein; Provisional; Region: PRK11616
585034011723	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
585034011724	putative oxidoreductase; Provisional; Region: PRK11445
585034011725	hypothetical protein; Provisional; Region: PRK07236
585034011726	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034011727	D-galactonate transporter; Region: 2A0114; TIGR00893
585034011728	putative substrate translocation pore; other site
585034011729	galactonate dehydratase; Provisional; Region: PRK14017
585034011730	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
585034011731	putative active site pocket [active]
585034011732	putative metal binding site [ion binding]; other site
585034011733	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
585034011734	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
585034011735	active site
585034011736	intersubunit interface [polypeptide binding]; other site
585034011737	catalytic residue [active]
585034011738	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
585034011739	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
585034011740	Transcriptional regulators [Transcription]; Region: FadR; COG2186
585034011741	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034011742	DNA-binding site [nucleotide binding]; DNA binding site
585034011743	FCD domain; Region: FCD; pfam07729
585034011744	hypothetical protein; Provisional; Region: PRK10215
585034011745	sugar phosphate phosphatase; Provisional; Region: PRK10513
585034011746	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034011747	active site
585034011748	motif I; other site
585034011749	motif II; other site
585034011750	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034011751	hypothetical protein; Provisional; Region: PRK11426
585034011752	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
585034011753	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034011754	Mg2+ binding site [ion binding]; other site
585034011755	G-X-G motif; other site
585034011756	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
585034011757	anchoring element; other site
585034011758	dimer interface [polypeptide binding]; other site
585034011759	ATP binding site [chemical binding]; other site
585034011760	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
585034011761	active site
585034011762	putative metal-binding site [ion binding]; other site
585034011763	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
585034011764	recF protein; Region: recf; TIGR00611
585034011765	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585034011766	Walker A/P-loop; other site
585034011767	ATP binding site [chemical binding]; other site
585034011768	Q-loop/lid; other site
585034011769	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585034011770	ABC transporter signature motif; other site
585034011771	Walker B; other site
585034011772	D-loop; other site
585034011773	H-loop/switch region; other site
585034011774	DNA polymerase III subunit beta; Validated; Region: PRK05643
585034011775	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
585034011776	putative DNA binding surface [nucleotide binding]; other site
585034011777	dimer interface [polypeptide binding]; other site
585034011778	beta-clamp/clamp loader binding surface; other site
585034011779	beta-clamp/translesion DNA polymerase binding surface; other site
585034011780	DnaA N-terminal domain; Region: DnaA_N; pfam11638
585034011781	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
585034011782	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034011783	Walker A motif; other site
585034011784	ATP binding site [chemical binding]; other site
585034011785	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
585034011786	Walker B motif; other site
585034011787	arginine finger; other site
585034011788	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
585034011789	DnaA box-binding interface [nucleotide binding]; other site
585034011790	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
585034011791	ribonuclease P; Reviewed; Region: rnpA; PRK01732
585034011792	hypothetical protein; Validated; Region: PRK00041
585034011793	membrane protein insertase; Provisional; Region: PRK01318
585034011794	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
585034011795	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
585034011796	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
585034011797	trmE is a tRNA modification GTPase; Region: trmE; cd04164
585034011798	G1 box; other site
585034011799	GTP/Mg2+ binding site [chemical binding]; other site
585034011800	Switch I region; other site
585034011801	G2 box; other site
585034011802	Switch II region; other site
585034011803	G3 box; other site
585034011804	G4 box; other site
585034011805	G5 box; other site
585034011806	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
585034011807	Tryptophanese operon leader peptide; Region: Tna_leader; pfam08053
585034011808	tryptophanase, leader peptide-associated; Region: tnaA_trp_ase; TIGR02617
585034011809	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
585034011810	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
585034011811	catalytic residue [active]
585034011812	tryptophan permease TnaB; Provisional; Region: PRK09664
585034011813	aromatic amino acid transport protein; Region: araaP; TIGR00837
585034011814	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
585034011815	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034011816	putative substrate translocation pore; other site
585034011817	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
585034011818	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034011819	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
585034011820	substrate binding pocket [chemical binding]; other site
585034011821	dimerization interface [polypeptide binding]; other site
585034011822	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
585034011823	Predicted flavoprotein [General function prediction only]; Region: COG0431
585034011824	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
585034011825	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
585034011826	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
585034011827	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034011828	active site
585034011829	motif I; other site
585034011830	motif II; other site
585034011831	putative inner membrane protein; Provisional; Region: PRK09823
585034011832	Uncharacterized protein family (UPF0167); Region: UPF0167; cl01252
585034011833	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
585034011834	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
585034011835	active site
585034011836	trimer interface [polypeptide binding]; other site
585034011837	allosteric site; other site
585034011838	active site lid [active]
585034011839	N-terminal Early set domain associated with the catalytic domain of putative esterases; Region: E_set_Esterase_like_N; cd11294
585034011840	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
585034011841	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
585034011842	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
585034011843	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
585034011844	trimer interface; other site
585034011845	sugar binding site [chemical binding]; other site
585034011846	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
585034011847	beta-galactosidase; Region: BGL; TIGR03356
585034011848	PTS system beta-glucoside-specific transporter subunits IIABC; Provisional; Region: PRK09824
585034011849	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
585034011850	active site turn [active]
585034011851	phosphorylation site [posttranslational modification]
585034011852	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
585034011853	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
585034011854	HPr interaction site; other site
585034011855	glycerol kinase (GK) interaction site [polypeptide binding]; other site
585034011856	active site
585034011857	phosphorylation site [posttranslational modification]
585034011858	transcriptional antiterminator BglG; Provisional; Region: PRK09772
585034011859	CAT RNA binding domain; Region: CAT_RBD; pfam03123
585034011860	PRD domain; Region: PRD; pfam00874
585034011861	PRD domain; Region: PRD; pfam00874
585034011862	transcriptional regulator PhoU; Provisional; Region: PRK11115
585034011863	PhoU domain; Region: PhoU; pfam01895
585034011864	PhoU domain; Region: PhoU; pfam01895
585034011865	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
585034011866	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
585034011867	Walker A/P-loop; other site
585034011868	ATP binding site [chemical binding]; other site
585034011869	Q-loop/lid; other site
585034011870	ABC transporter signature motif; other site
585034011871	Walker B; other site
585034011872	D-loop; other site
585034011873	H-loop/switch region; other site
585034011874	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
585034011875	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034011876	dimer interface [polypeptide binding]; other site
585034011877	conserved gate region; other site
585034011878	putative PBP binding loops; other site
585034011879	ABC-ATPase subunit interface; other site
585034011880	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
585034011881	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034011882	dimer interface [polypeptide binding]; other site
585034011883	conserved gate region; other site
585034011884	putative PBP binding loops; other site
585034011885	ABC-ATPase subunit interface; other site
585034011886	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585034011887	Fimbrial protein; Region: Fimbrial; cl01416
585034011888	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
585034011889	PapC N-terminal domain; Region: PapC_N; pfam13954
585034011890	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585034011891	PapC C-terminal domain; Region: PapC_C; pfam13953
585034011892	fimbrial chaperone protein; Provisional; Region: lfpB; PRK15290
585034011893	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585034011894	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
585034011895	fimbrial protein; Provisional; Region: lpfA; PRK15289
585034011896	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
585034011897	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
585034011898	glutaminase active site [active]
585034011899	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
585034011900	dimer interface [polypeptide binding]; other site
585034011901	active site
585034011902	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
585034011903	dimer interface [polypeptide binding]; other site
585034011904	active site
585034011905	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
585034011906	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
585034011907	Substrate binding site; other site
585034011908	Mg++ binding site; other site
585034011909	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
585034011910	active site
585034011911	substrate binding site [chemical binding]; other site
585034011912	CoA binding site [chemical binding]; other site
585034011913	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
585034011914	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
585034011915	gamma subunit interface [polypeptide binding]; other site
585034011916	epsilon subunit interface [polypeptide binding]; other site
585034011917	LBP interface [polypeptide binding]; other site
585034011918	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
585034011919	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
585034011920	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
585034011921	alpha subunit interaction interface [polypeptide binding]; other site
585034011922	Walker A motif; other site
585034011923	ATP binding site [chemical binding]; other site
585034011924	Walker B motif; other site
585034011925	inhibitor binding site; inhibition site
585034011926	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
585034011927	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
585034011928	core domain interface [polypeptide binding]; other site
585034011929	delta subunit interface [polypeptide binding]; other site
585034011930	epsilon subunit interface [polypeptide binding]; other site
585034011931	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
585034011932	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
585034011933	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
585034011934	beta subunit interaction interface [polypeptide binding]; other site
585034011935	Walker A motif; other site
585034011936	ATP binding site [chemical binding]; other site
585034011937	Walker B motif; other site
585034011938	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
585034011939	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
585034011940	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
585034011941	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
585034011942	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
585034011943	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
585034011944	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
585034011945	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
585034011946	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
585034011947	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
585034011948	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034011949	S-adenosylmethionine binding site [chemical binding]; other site
585034011950	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
585034011951	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
585034011952	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
585034011953	FMN-binding protein MioC; Provisional; Region: PRK09004
585034011954	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
585034011955	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
585034011956	putative DNA binding site [nucleotide binding]; other site
585034011957	putative Zn2+ binding site [ion binding]; other site
585034011958	AsnC family; Region: AsnC_trans_reg; pfam01037
585034011959	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
585034011960	dimer interface [polypeptide binding]; other site
585034011961	active site
585034011962	hypothetical protein; Provisional; Region: yieM; PRK10997
585034011963	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
585034011964	metal ion-dependent adhesion site (MIDAS); other site
585034011965	regulatory ATPase RavA; Provisional; Region: PRK13531
585034011966	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034011967	Walker A motif; other site
585034011968	ATP binding site [chemical binding]; other site
585034011969	Walker B motif; other site
585034011970	arginine finger; other site
585034011971	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
585034011972	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
585034011973	potassium uptake protein; Region: kup; TIGR00794
585034011974	D-ribose pyranase; Provisional; Region: PRK11797
585034011975	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
585034011976	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
585034011977	Walker A/P-loop; other site
585034011978	ATP binding site [chemical binding]; other site
585034011979	Q-loop/lid; other site
585034011980	ABC transporter signature motif; other site
585034011981	Walker B; other site
585034011982	D-loop; other site
585034011983	H-loop/switch region; other site
585034011984	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
585034011985	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585034011986	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585034011987	TM-ABC transporter signature motif; other site
585034011988	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
585034011989	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
585034011990	ligand binding site [chemical binding]; other site
585034011991	dimerization interface [polypeptide binding]; other site
585034011992	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
585034011993	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
585034011994	substrate binding site [chemical binding]; other site
585034011995	dimer interface [polypeptide binding]; other site
585034011996	ATP binding site [chemical binding]; other site
585034011997	transcriptional repressor RbsR; Provisional; Region: PRK10423
585034011998	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585034011999	DNA binding site [nucleotide binding]
585034012000	domain linker motif; other site
585034012001	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
585034012002	dimerization interface [polypeptide binding]; other site
585034012003	ligand binding site [chemical binding]; other site
585034012004	putative transporter; Provisional; Region: PRK10504
585034012005	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034012006	putative substrate translocation pore; other site
585034012007	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034012008	Transcriptional regulators [Transcription]; Region: FadR; COG2186
585034012009	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034012010	DNA-binding site [nucleotide binding]; DNA binding site
585034012011	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
585034012012	transcriptional regulator HdfR; Provisional; Region: PRK03601
585034012013	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034012014	LysR substrate binding domain; Region: LysR_substrate; pfam03466
585034012015	dimerization interface [polypeptide binding]; other site
585034012016	hypothetical protein; Provisional; Region: PRK11027
585034012017	putative ATP-dependent protease; Provisional; Region: PRK09862
585034012018	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
585034012019	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034012020	Walker A motif; other site
585034012021	ATP binding site [chemical binding]; other site
585034012022	Walker B motif; other site
585034012023	arginine finger; other site
585034012024	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
585034012025	ilvG operon leader peptide; Provisional; Region: PRK10424
585034012026	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
585034012027	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
585034012028	PYR/PP interface [polypeptide binding]; other site
585034012029	dimer interface [polypeptide binding]; other site
585034012030	TPP binding site [chemical binding]; other site
585034012031	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
585034012032	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
585034012033	TPP-binding site [chemical binding]; other site
585034012034	dimer interface [polypeptide binding]; other site
585034012035	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
585034012036	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
585034012037	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
585034012038	homodimer interface [polypeptide binding]; other site
585034012039	substrate-cofactor binding pocket; other site
585034012040	catalytic residue [active]
585034012041	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
585034012042	threonine dehydratase; Reviewed; Region: PRK09224
585034012043	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
585034012044	tetramer interface [polypeptide binding]; other site
585034012045	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034012046	catalytic residue [active]
585034012047	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
585034012048	putative Ile/Val binding site [chemical binding]; other site
585034012049	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
585034012050	putative Ile/Val binding site [chemical binding]; other site
585034012051	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034012052	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
585034012053	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
585034012054	putative dimerization interface [polypeptide binding]; other site
585034012055	ketol-acid reductoisomerase; Validated; Region: PRK05225
585034012056	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
585034012057	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
585034012058	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
585034012059	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
585034012060	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
585034012061	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3692
585034012062	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
585034012063	Part of AAA domain; Region: AAA_19; pfam13245
585034012064	Family description; Region: UvrD_C_2; pfam13538
585034012065	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
585034012066	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
585034012067	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
585034012068	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
585034012069	ATP binding site [chemical binding]; other site
585034012070	Mg++ binding site [ion binding]; other site
585034012071	motif III; other site
585034012072	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585034012073	nucleotide binding region [chemical binding]; other site
585034012074	ATP-binding site [chemical binding]; other site
585034012075	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
585034012076	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
585034012077	catalytic residues [active]
585034012078	putative rho operon leader peptide; Provisional; Region: PRK09979
585034012079	transcription termination factor Rho; Provisional; Region: rho; PRK09376
585034012080	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
585034012081	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
585034012082	RNA binding site [nucleotide binding]; other site
585034012083	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
585034012084	multimer interface [polypeptide binding]; other site
585034012085	Walker A motif; other site
585034012086	ATP binding site [chemical binding]; other site
585034012087	Walker B motif; other site
585034012088	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
585034012089	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
585034012090	Mg++ binding site [ion binding]; other site
585034012091	putative catalytic motif [active]
585034012092	substrate binding site [chemical binding]; other site
585034012093	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
585034012094	Chain length determinant protein; Region: Wzz; pfam02706
585034012095	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
585034012096	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
585034012097	active site
585034012098	homodimer interface [polypeptide binding]; other site
585034012099	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
585034012100	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
585034012101	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
585034012102	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
585034012103	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
585034012104	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
585034012105	NAD binding site [chemical binding]; other site
585034012106	substrate binding site [chemical binding]; other site
585034012107	homodimer interface [polypeptide binding]; other site
585034012108	active site
585034012109	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
585034012110	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
585034012111	substrate binding site; other site
585034012112	tetramer interface; other site
585034012113	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
585034012114	Coenzyme A binding pocket [chemical binding]; other site
585034012115	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
585034012116	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
585034012117	inhibitor-cofactor binding pocket; inhibition site
585034012118	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034012119	catalytic residue [active]
585034012120	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
585034012121	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
585034012122	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
585034012123	putative common antigen polymerase; Provisional; Region: PRK02975
585034012124	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
585034012125	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
585034012126	putative transport protein YifK; Provisional; Region: PRK10746
585034012127	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
585034012128	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585034012129	FeS/SAM binding site; other site
585034012130	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
585034012131	fragment of arylsulfatase-like enzyme (partial);Evidence 7 : Gene remnant; Product type e : enzyme
585034012132	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
585034012133	HemY protein N-terminus; Region: HemY_N; pfam07219
585034012134	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
585034012135	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
585034012136	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
585034012137	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
585034012138	active site
585034012139	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
585034012140	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
585034012141	domain interfaces; other site
585034012142	active site
585034012143	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
585034012144	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
585034012145	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
585034012146	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
585034012147	putative iron binding site [ion binding]; other site
585034012148	DKNYY family; Region: DKNYY; pfam13644
585034012149	Protein of unknown function (DUF3304); Region: DUF3304; pfam11745
585034012150	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
585034012151	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
585034012152	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
585034012153	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
585034012154	hypothetical protein; Provisional; Region: PRK10963
585034012155	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
585034012156	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
585034012157	active site
585034012158	DNA binding site [nucleotide binding]
585034012159	Int/Topo IB signature motif; other site
585034012160	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
585034012161	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034012162	motif II; other site
585034012163	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
585034012164	Part of AAA domain; Region: AAA_19; pfam13245
585034012165	Family description; Region: UvrD_C_2; pfam13538
585034012166	Predicted periplasmic protein [Function unknown]; Region: COG3698
585034012167	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
585034012168	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
585034012169	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
585034012170	Cl binding site [ion binding]; other site
585034012171	oligomer interface [polypeptide binding]; other site
585034012172	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
585034012173	Protein of unknown function (DUF3289); Region: DUF3289; cl11840
585034012174	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
585034012175	magnesium/nickel/cobalt transporter CorA; Provisional; Region: PRK11085
585034012176	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
585034012177	EamA-like transporter family; Region: EamA; cl17759
585034012178	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
585034012179	CoenzymeA binding site [chemical binding]; other site
585034012180	subunit interaction site [polypeptide binding]; other site
585034012181	PHB binding site; other site
585034012182	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
585034012183	dimerization interface [polypeptide binding]; other site
585034012184	substrate binding site [chemical binding]; other site
585034012185	active site
585034012186	calcium binding site [ion binding]; other site
585034012187	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
585034012188	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585034012189	ATP binding site [chemical binding]; other site
585034012190	putative Mg++ binding site [ion binding]; other site
585034012191	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
585034012192	nucleotide binding region [chemical binding]; other site
585034012193	ATP-binding site [chemical binding]; other site
585034012194	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
585034012195	Helicase and RNase D C-terminal; Region: HRDC; smart00341
585034012196	threonine efflux system; Provisional; Region: PRK10229
585034012197	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
585034012198	lysophospholipase L2; Provisional; Region: PRK10749
585034012199	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
585034012200	putative hydrolase; Provisional; Region: PRK10976
585034012201	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034012202	active site
585034012203	motif I; other site
585034012204	motif II; other site
585034012205	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034012206	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
585034012207	EamA-like transporter family; Region: EamA; pfam00892
585034012208	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
585034012209	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034012210	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
585034012211	putative dimerization interface [polypeptide binding]; other site
585034012212	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
585034012213	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
585034012214	THF binding site; other site
585034012215	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
585034012216	substrate binding site [chemical binding]; other site
585034012217	THF binding site; other site
585034012218	zinc-binding site [ion binding]; other site
585034012219	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
585034012220	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
585034012221	uridine phosphorylase; Provisional; Region: PRK11178
585034012222	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
585034012223	DNA recombination protein RmuC; Provisional; Region: PRK10361
585034012224	RmuC family; Region: RmuC; pfam02646
585034012225	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
585034012226	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034012227	S-adenosylmethionine binding site [chemical binding]; other site
585034012228	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
585034012229	SCP-2 sterol transfer family; Region: SCP2; pfam02036
585034012230	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
585034012231	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
585034012232	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
585034012233	twin arginine translocase protein A; Provisional; Region: tatA; PRK00575
585034012234	sec-independent translocase; Provisional; Region: PRK01770
585034012235	sec-independent translocase; Provisional; Region: tatB; PRK00404
585034012236	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
585034012237	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
585034012238	active site
585034012239	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
585034012240	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
585034012241	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
585034012242	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
585034012243	FMN reductase; Validated; Region: fre; PRK08051
585034012244	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
585034012245	FAD binding pocket [chemical binding]; other site
585034012246	FAD binding motif [chemical binding]; other site
585034012247	phosphate binding motif [ion binding]; other site
585034012248	beta-alpha-beta structure motif; other site
585034012249	NAD binding pocket [chemical binding]; other site
585034012250	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
585034012251	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
585034012252	dimer interface [polypeptide binding]; other site
585034012253	active site
585034012254	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
585034012255	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
585034012256	substrate binding site [chemical binding]; other site
585034012257	oxyanion hole (OAH) forming residues; other site
585034012258	trimer interface [polypeptide binding]; other site
585034012259	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
585034012260	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
585034012261	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
585034012262	proline dipeptidase; Provisional; Region: PRK13607
585034012263	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
585034012264	active site
585034012265	hypothetical protein; Provisional; Region: PRK11568
585034012266	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
585034012267	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
585034012268	potassium transporter; Provisional; Region: PRK10750
585034012269	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
585034012270	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
585034012271	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
585034012272	Walker A motif; other site
585034012273	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
585034012274	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
585034012275	GTP binding site; other site
585034012276	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
585034012277	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
585034012278	serine/threonine protein kinase; Provisional; Region: PRK11768
585034012279	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
585034012280	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
585034012281	catalytic residues [active]
585034012282	hinge region; other site
585034012283	alpha helical domain; other site
585034012284	hypothetical protein; Provisional; Region: PRK11367
585034012285	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
585034012286	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
585034012287	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
585034012288	putative acyl-acceptor binding pocket; other site
585034012289	DNA polymerase I; Provisional; Region: PRK05755
585034012290	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
585034012291	active site
585034012292	metal binding site 1 [ion binding]; metal-binding site
585034012293	putative 5' ssDNA interaction site; other site
585034012294	metal binding site 3; metal-binding site
585034012295	metal binding site 2 [ion binding]; metal-binding site
585034012296	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
585034012297	putative DNA binding site [nucleotide binding]; other site
585034012298	putative metal binding site [ion binding]; other site
585034012299	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
585034012300	active site
585034012301	catalytic site [active]
585034012302	substrate binding site [chemical binding]; other site
585034012303	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
585034012304	active site
585034012305	DNA binding site [nucleotide binding]
585034012306	catalytic site [active]
585034012307	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
585034012308	G1 box; other site
585034012309	GTP/Mg2+ binding site [chemical binding]; other site
585034012310	Switch I region; other site
585034012311	G2 box; other site
585034012312	G3 box; other site
585034012313	Switch II region; other site
585034012314	G4 box; other site
585034012315	G5 box; other site
585034012316	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
585034012317	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
585034012318	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585034012319	FeS/SAM binding site; other site
585034012320	HemN C-terminal domain; Region: HemN_C; pfam06969
585034012321	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
585034012322	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034012323	active site
585034012324	phosphorylation site [posttranslational modification]
585034012325	intermolecular recognition site; other site
585034012326	dimerization interface [polypeptide binding]; other site
585034012327	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034012328	Walker A motif; other site
585034012329	ATP binding site [chemical binding]; other site
585034012330	Walker B motif; other site
585034012331	arginine finger; other site
585034012332	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
585034012333	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
585034012334	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
585034012335	putative active site [active]
585034012336	heme pocket [chemical binding]; other site
585034012337	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585034012338	dimer interface [polypeptide binding]; other site
585034012339	phosphorylation site [posttranslational modification]
585034012340	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034012341	ATP binding site [chemical binding]; other site
585034012342	Mg2+ binding site [ion binding]; other site
585034012343	G-X-G motif; other site
585034012344	glutamine synthetase; Provisional; Region: glnA; PRK09469
585034012345	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
585034012346	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
585034012347	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
585034012348	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
585034012349	G1 box; other site
585034012350	putative GEF interaction site [polypeptide binding]; other site
585034012351	GTP/Mg2+ binding site [chemical binding]; other site
585034012352	Switch I region; other site
585034012353	G2 box; other site
585034012354	G3 box; other site
585034012355	Switch II region; other site
585034012356	G4 box; other site
585034012357	G5 box; other site
585034012358	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
585034012359	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
585034012360	transcriptional regulator protein; Region: phnR; TIGR03337
585034012361	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034012362	DNA-binding site [nucleotide binding]; DNA binding site
585034012363	UTRA domain; Region: UTRA; pfam07702
585034012364	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
585034012365	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034012366	putative substrate translocation pore; other site
585034012367	phosphoglycerate transporter family protein; Region: 2A0104; TIGR00881
585034012368	outer membrane porin L; Provisional; Region: ompL; PRK09980
585034012369	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
585034012370	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034012371	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
585034012372	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
585034012373	alpha-glucosidase; Provisional; Region: PRK10426
585034012374	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
585034012375	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
585034012376	putative active site [active]
585034012377	putative catalytic site [active]
585034012378	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
585034012379	active site
585034012380	catalytic residues [active]
585034012381	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
585034012382	dimerization interface [polypeptide binding]; other site
585034012383	putative active cleft [active]
585034012384	Tagatose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]; Region: LacD; COG3684
585034012385	catalytic residue [active]
585034012386	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
585034012387	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
585034012388	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
585034012389	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
585034012390	substrate binding site [chemical binding]; other site
585034012391	ATP binding site [chemical binding]; other site
585034012392	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
585034012393	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
585034012394	putative DNA binding site [nucleotide binding]; other site
585034012395	putative Zn2+ binding site [ion binding]; other site
585034012396	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585034012397	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
585034012398	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034012399	motif II; other site
585034012400	hypothetical protein; Reviewed; Region: PRK01637
585034012401	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
585034012402	putative active site [active]
585034012403	dimerization interface [polypeptide binding]; other site
585034012404	putative tRNAtyr binding site [nucleotide binding]; other site
585034012405	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585034012406	Coenzyme A binding pocket [chemical binding]; other site
585034012407	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
585034012408	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
585034012409	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
585034012410	substrate binding pocket [chemical binding]; other site
585034012411	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585034012412	non-specific DNA binding site [nucleotide binding]; other site
585034012413	salt bridge; other site
585034012414	sequence-specific DNA binding site [nucleotide binding]; other site
585034012415	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
585034012416	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
585034012417	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
585034012418	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
585034012419	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
585034012420	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
585034012421	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
585034012422	formate dehydrogenase, alpha subunit, proteobacterial-type; Region: formate-DH-alph; TIGR01553
585034012423	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
585034012424	[4Fe-4S] binding site [ion binding]; other site
585034012425	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
585034012426	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
585034012427	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
585034012428	molybdopterin cofactor binding site; other site
585034012429	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
585034012430	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
585034012431	putative frv operon regulatory protein; Provisional; Region: PRK09863
585034012432	HTH domain; Region: HTH_11; pfam08279
585034012433	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
585034012434	active site
585034012435	phosphorylation site [posttranslational modification]
585034012436	putative peptidase; Provisional; Region: PRK09864
585034012437	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
585034012438	oligomer interface [polypeptide binding]; other site
585034012439	active site
585034012440	metal binding site [ion binding]; metal-binding site
585034012441	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
585034012442	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
585034012443	active site
585034012444	P-loop; other site
585034012445	phosphorylation site [posttranslational modification]
585034012446	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
585034012447	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
585034012448	active site
585034012449	phosphorylation site [posttranslational modification]
585034012450	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
585034012451	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
585034012452	intersubunit interface [polypeptide binding]; other site
585034012453	active site
585034012454	Zn2+ binding site [ion binding]; other site
585034012455	L-rhamnose isomerase; Provisional; Region: PRK01076
585034012456	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
585034012457	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
585034012458	N- and C-terminal domain interface [polypeptide binding]; other site
585034012459	active site
585034012460	putative catalytic site [active]
585034012461	metal binding site [ion binding]; metal-binding site
585034012462	ATP binding site [chemical binding]; other site
585034012463	rhamnulokinase; Provisional; Region: rhaB; PRK10640
585034012464	carbohydrate binding site [chemical binding]; other site
585034012465	transcriptional activator RhaS; Provisional; Region: PRK13503
585034012466	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
585034012467	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034012468	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034012469	transcriptional activator RhaR; Provisional; Region: PRK13500
585034012470	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
585034012471	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034012472	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034012473	L-rhamnose-proton symport protein (RhaT); Region: RhaT; cl05728
585034012474	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
585034012475	superoxide dismutase; Provisional; Region: PRK10925
585034012476	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
585034012477	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
585034012478	2-keto-3-deoxygluconate transporter; Region: kdgT; TIGR00793
585034012479	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
585034012480	MOSC domain; Region: MOSC; pfam03473
585034012481	3-alpha domain; Region: 3-alpha; pfam03475
585034012482	two-component sensor protein; Provisional; Region: cpxA; PRK09470
585034012483	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585034012484	dimerization interface [polypeptide binding]; other site
585034012485	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585034012486	dimer interface [polypeptide binding]; other site
585034012487	phosphorylation site [posttranslational modification]
585034012488	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034012489	ATP binding site [chemical binding]; other site
585034012490	Mg2+ binding site [ion binding]; other site
585034012491	G-X-G motif; other site
585034012492	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
585034012493	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034012494	active site
585034012495	intermolecular recognition site; other site
585034012496	dimerization interface [polypeptide binding]; other site
585034012497	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585034012498	DNA binding site [nucleotide binding]
585034012499	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
585034012500	dimer interface [polypeptide binding]; other site
585034012501	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
585034012502	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
585034012503	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
585034012504	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
585034012505	active site
585034012506	ADP/pyrophosphate binding site [chemical binding]; other site
585034012507	dimerization interface [polypeptide binding]; other site
585034012508	allosteric effector site; other site
585034012509	fructose-1,6-bisphosphate binding site; other site
585034012510	sulfate transporter subunit; Provisional; Region: PRK10752
585034012511	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
585034012512	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
585034012513	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
585034012514	triosephosphate isomerase; Provisional; Region: PRK14567
585034012515	substrate binding site [chemical binding]; other site
585034012516	dimer interface [polypeptide binding]; other site
585034012517	catalytic triad [active]
585034012518	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
585034012519	Predicted membrane protein [Function unknown]; Region: COG3152
585034012520	hypothetical protein; Provisional; Region: PRK09981
585034012521	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
585034012522	Ligand Binding Site [chemical binding]; other site
585034012523	ferredoxin-NADP reductase; Provisional; Region: PRK10926
585034012524	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
585034012525	FAD binding pocket [chemical binding]; other site
585034012526	FAD binding motif [chemical binding]; other site
585034012527	phosphate binding motif [ion binding]; other site
585034012528	beta-alpha-beta structure motif; other site
585034012529	NAD binding pocket [chemical binding]; other site
585034012530	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
585034012531	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
585034012532	putative active site [active]
585034012533	glycerol kinase; Provisional; Region: glpK; PRK00047
585034012534	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
585034012535	N- and C-terminal domain interface [polypeptide binding]; other site
585034012536	active site
585034012537	MgATP binding site [chemical binding]; other site
585034012538	catalytic site [active]
585034012539	metal binding site [ion binding]; metal-binding site
585034012540	glycerol binding site [chemical binding]; other site
585034012541	homotetramer interface [polypeptide binding]; other site
585034012542	homodimer interface [polypeptide binding]; other site
585034012543	FBP binding site [chemical binding]; other site
585034012544	protein IIAGlc interface [polypeptide binding]; other site
585034012545	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
585034012546	amphipathic channel; other site
585034012547	Asn-Pro-Ala signature motifs; other site
585034012548	septal ring assembly protein ZapB; Provisional; Region: PRK15422
585034012549	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
585034012550	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
585034012551	UbiA prenyltransferase family; Region: UbiA; pfam01040
585034012552	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
585034012553	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034012554	Walker A motif; other site
585034012555	ATP binding site [chemical binding]; other site
585034012556	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
585034012557	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
585034012558	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
585034012559	active site
585034012560	HslU subunit interaction site [polypeptide binding]; other site
585034012561	essential cell division protein FtsN; Provisional; Region: PRK10927
585034012562	cell division protein FtsN; Provisional; Region: PRK12757
585034012563	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585034012564	DNA binding site [nucleotide binding]
585034012565	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
585034012566	domain linker motif; other site
585034012567	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
585034012568	dimerization interface [polypeptide binding]; other site
585034012569	ligand binding site [chemical binding]; other site
585034012570	primosome assembly protein PriA; Validated; Region: PRK05580
585034012571	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
585034012572	ATP binding site [chemical binding]; other site
585034012573	putative Mg++ binding site [ion binding]; other site
585034012574	helicase superfamily c-terminal domain; Region: HELICc; smart00490
585034012575	ATP-binding site [chemical binding]; other site
585034012576	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
585034012577	fragment of rhsB element core protein RshB (part 1);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585034012578	fragment of rhsB element core protein RshB (part 2);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585034012579	fragment of IS1 transposase InsAB' (part 2);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585034012580	fragment of IS1 transposase InsAB' (part 1);Evidence 7 : Gene remnant; Product type h : extrachromosomal origin
585034012581	hypothetical protein; Provisional; Region: PRK10030
585034012582	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
585034012583	dimerization interface [polypeptide binding]; other site
585034012584	DNA binding site [nucleotide binding]
585034012585	corepressor binding sites; other site
585034012586	cystathionine gamma-synthase; Provisional; Region: PRK08045
585034012587	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
585034012588	homodimer interface [polypeptide binding]; other site
585034012589	substrate-cofactor binding pocket; other site
585034012590	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034012591	catalytic residue [active]
585034012592	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
585034012593	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
585034012594	putative catalytic residues [active]
585034012595	putative nucleotide binding site [chemical binding]; other site
585034012596	putative aspartate binding site [chemical binding]; other site
585034012597	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
585034012598	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
585034012599	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
585034012600	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
585034012601	FAD binding site [chemical binding]; other site
585034012602	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
585034012603	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
585034012604	heme binding site [chemical binding]; other site
585034012605	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
585034012606	EamA-like transporter family; Region: EamA; pfam00892
585034012607	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
585034012608	EamA-like transporter family; Region: EamA; pfam00892
585034012609	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
585034012610	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
585034012611	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
585034012612	dimer interface [polypeptide binding]; other site
585034012613	active site
585034012614	metal binding site [ion binding]; metal-binding site
585034012615	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
585034012616	active site
585034012617	intersubunit interactions; other site
585034012618	catalytic residue [active]
585034012619	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
585034012620	dimerization domain swap beta strand [polypeptide binding]; other site
585034012621	regulatory protein interface [polypeptide binding]; other site
585034012622	active site
585034012623	regulatory phosphorylation site [posttranslational modification]; other site
585034012624	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
585034012625	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
585034012626	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
585034012627	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
585034012628	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
585034012629	active site
585034012630	phosphorylation site [posttranslational modification]
585034012631	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
585034012632	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
585034012633	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
585034012634	active site
585034012635	P-loop; other site
585034012636	phosphorylation site [posttranslational modification]
585034012637	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
585034012638	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
585034012639	dimer interface [polypeptide binding]; other site
585034012640	active site
585034012641	glycine loop; other site
585034012642	pyruvate formate lyase II activase; Provisional; Region: PRK10076
585034012643	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
585034012644	active site
585034012645	P-loop; other site
585034012646	phosphorylation site [posttranslational modification]
585034012647	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
585034012648	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034012649	hypothetical protein; Provisional; Region: PRK10649
585034012650	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
585034012651	Sulfatase; Region: Sulfatase; pfam00884
585034012652	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
585034012653	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
585034012654	acetylornithine deacetylase; Provisional; Region: PRK05111
585034012655	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
585034012656	metal binding site [ion binding]; metal-binding site
585034012657	putative dimer interface [polypeptide binding]; other site
585034012658	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
585034012659	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
585034012660	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
585034012661	nucleotide binding site [chemical binding]; other site
585034012662	N-acetyl-L-glutamate binding site [chemical binding]; other site
585034012663	argininosuccinate lyase; Provisional; Region: PRK04833
585034012664	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
585034012665	active sites [active]
585034012666	tetramer interface [polypeptide binding]; other site
585034012667	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
585034012668	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
585034012669	putative active site pocket [active]
585034012670	putative metal binding site [ion binding]; other site
585034012671	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034012672	D-galactonate transporter; Region: 2A0114; TIGR00893
585034012673	putative substrate translocation pore; other site
585034012674	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
585034012675	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034012676	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
585034012677	dimerization interface [polypeptide binding]; other site
585034012678	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
585034012679	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
585034012680	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
585034012681	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
585034012682	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585034012683	hypothetical protein; Provisional; Region: PRK11056
585034012684	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
585034012685	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034012686	S-adenosylmethionine binding site [chemical binding]; other site
585034012687	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
585034012688	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
585034012689	N-terminal plug; other site
585034012690	ligand-binding site [chemical binding]; other site
585034012691	glutamate racemase; Provisional; Region: PRK00865
585034012692	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
585034012693	FAD binding domain; Region: FAD_binding_4; pfam01565
585034012694	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
585034012695	Biotin operon repressor [Transcription]; Region: BirA; COG1654
585034012696	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
585034012697	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
585034012698	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
585034012699	pantothenate kinase; Provisional; Region: PRK05439
585034012700	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
585034012701	ATP-binding site [chemical binding]; other site
585034012702	CoA-binding site [chemical binding]; other site
585034012703	Mg2+-binding site [ion binding]; other site
585034012704	elongation factor Tu; Reviewed; Region: PRK00049
585034012705	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
585034012706	G1 box; other site
585034012707	GEF interaction site [polypeptide binding]; other site
585034012708	GTP/Mg2+ binding site [chemical binding]; other site
585034012709	Switch I region; other site
585034012710	G2 box; other site
585034012711	G3 box; other site
585034012712	Switch II region; other site
585034012713	G4 box; other site
585034012714	G5 box; other site
585034012715	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
585034012716	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
585034012717	Antibiotic Binding Site [chemical binding]; other site
585034012718	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
585034012719	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
585034012720	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
585034012721	putative homodimer interface [polypeptide binding]; other site
585034012722	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
585034012723	heterodimer interface [polypeptide binding]; other site
585034012724	homodimer interface [polypeptide binding]; other site
585034012725	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
585034012726	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
585034012727	23S rRNA interface [nucleotide binding]; other site
585034012728	L7/L12 interface [polypeptide binding]; other site
585034012729	putative thiostrepton binding site; other site
585034012730	L25 interface [polypeptide binding]; other site
585034012731	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
585034012732	mRNA/rRNA interface [nucleotide binding]; other site
585034012733	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
585034012734	23S rRNA interface [nucleotide binding]; other site
585034012735	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
585034012736	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
585034012737	core dimer interface [polypeptide binding]; other site
585034012738	peripheral dimer interface [polypeptide binding]; other site
585034012739	L10 interface [polypeptide binding]; other site
585034012740	L11 interface [polypeptide binding]; other site
585034012741	putative EF-Tu interaction site [polypeptide binding]; other site
585034012742	putative EF-G interaction site [polypeptide binding]; other site
585034012743	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
585034012744	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
585034012745	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
585034012746	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
585034012747	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
585034012748	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
585034012749	RPB3 interaction site [polypeptide binding]; other site
585034012750	RPB1 interaction site [polypeptide binding]; other site
585034012751	RPB11 interaction site [polypeptide binding]; other site
585034012752	RPB10 interaction site [polypeptide binding]; other site
585034012753	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
585034012754	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
585034012755	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
585034012756	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
585034012757	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
585034012758	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
585034012759	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
585034012760	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
585034012761	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
585034012762	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
585034012763	DNA binding site [nucleotide binding]
585034012764	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
585034012765	stationary phase growth adaptation protein; Provisional; Region: PRK09717
585034012766	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
585034012767	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585034012768	FeS/SAM binding site; other site
585034012769	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
585034012770	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
585034012771	ThiS interaction site; other site
585034012772	putative active site [active]
585034012773	tetramer interface [polypeptide binding]; other site
585034012774	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
585034012775	thiS-thiF/thiG interaction site; other site
585034012776	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
585034012777	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
585034012778	ATP binding site [chemical binding]; other site
585034012779	substrate interface [chemical binding]; other site
585034012780	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
585034012781	thiamine phosphate binding site [chemical binding]; other site
585034012782	active site
585034012783	pyrophosphate binding site [ion binding]; other site
585034012784	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
585034012785	ThiC-associated domain; Region: ThiC-associated; pfam13667
585034012786	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
585034012787	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
585034012788	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
585034012789	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
585034012790	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
585034012791	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
585034012792	putative NADH binding site [chemical binding]; other site
585034012793	putative active site [active]
585034012794	nudix motif; other site
585034012795	putative metal binding site [ion binding]; other site
585034012796	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
585034012797	substrate binding site [chemical binding]; other site
585034012798	active site
585034012799	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
585034012800	Active_site [active]
585034012801	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
585034012802	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
585034012803	IHF dimer interface [polypeptide binding]; other site
585034012804	IHF - DNA interface [nucleotide binding]; other site
585034012805	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
585034012806	zinc resistance protein; Provisional; Region: zraP; PRK11546
585034012807	dimer interface [polypeptide binding]; other site
585034012808	sensor protein ZraS; Provisional; Region: PRK10364
585034012809	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585034012810	dimer interface [polypeptide binding]; other site
585034012811	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034012812	ATP binding site [chemical binding]; other site
585034012813	Mg2+ binding site [ion binding]; other site
585034012814	G-X-G motif; other site
585034012815	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
585034012816	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034012817	active site
585034012818	phosphorylation site [posttranslational modification]
585034012819	intermolecular recognition site; other site
585034012820	dimerization interface [polypeptide binding]; other site
585034012821	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034012822	Walker A motif; other site
585034012823	ATP binding site [chemical binding]; other site
585034012824	Walker B motif; other site
585034012825	arginine finger; other site
585034012826	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
585034012827	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
585034012828	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
585034012829	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
585034012830	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
585034012831	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
585034012832	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
585034012833	purine monophosphate binding site [chemical binding]; other site
585034012834	dimer interface [polypeptide binding]; other site
585034012835	putative catalytic residues [active]
585034012836	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
585034012837	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
585034012838	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585034012839	Coenzyme A binding pocket [chemical binding]; other site
585034012840	homoserine O-succinyltransferase; Provisional; Region: PRK05368
585034012841	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
585034012842	proposed active site lysine [active]
585034012843	conserved cys residue [active]
585034012844	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
585034012845	malate synthase A; Region: malate_syn_A; TIGR01344
585034012846	active site
585034012847	isocitrate lyase; Provisional; Region: PRK15063
585034012848	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
585034012849	tetramer interface [polypeptide binding]; other site
585034012850	active site
585034012851	Mg2+/Mn2+ binding site [ion binding]; other site
585034012852	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
585034012853	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
585034012854	fragment of regulator of acetyl CoA synthetase (part 2);Evidence 7 : Gene remnant; Product type r : regulator
585034012855	fragment of regulator of acetyl CoA synthetase (part 1);Evidence 7 : Gene remnant; Product type r : regulator
585034012856	transcriptional repressor IclR; Provisional; Region: PRK11569
585034012857	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
585034012858	Bacterial transcriptional regulator; Region: IclR; pfam01614
585034012859	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
585034012860	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
585034012861	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
585034012862	substrate binding pocket [chemical binding]; other site
585034012863	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
585034012864	B12 binding site [chemical binding]; other site
585034012865	cobalt ligand [ion binding]; other site
585034012866	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
585034012867	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
585034012868	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
585034012869	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
585034012870	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
585034012871	active site pocket [active]
585034012872	oxyanion hole [active]
585034012873	catalytic triad [active]
585034012874	active site nucleophile [active]
585034012875	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
585034012876	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
585034012877	RNA binding surface [nucleotide binding]; other site
585034012878	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
585034012879	probable active site [active]
585034012880	hypothetical protein; Provisional; Region: PRK10515
585034012881	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
585034012882	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
585034012883	Predicted nucleotidyltransferase; Region: Nuc-transf; pfam10127
585034012884	Zeta toxin; Region: Zeta_toxin; pfam06414
585034012885	aspartate kinase III; Validated; Region: PRK09084
585034012886	AAK_AKiii-LysC-EC: Amino Acid Kinase Superfamily (AAK), AKiii-LysC-EC: this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKIII. AKIII is a monofunctional class enzyme (LysC) found in some...; Region: AAK_AKiii-LysC-EC; cd04258
585034012887	nucleotide binding site [chemical binding]; other site
585034012888	putative catalytic residues [active]
585034012889	aspartate binding site [chemical binding]; other site
585034012890	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_1; cd04932
585034012891	lysine allosteric regulatory site; other site
585034012892	dimer interface [polypeptide binding]; other site
585034012893	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
585034012894	dimer interface [polypeptide binding]; other site
585034012895	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
585034012896	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
585034012897	active site
585034012898	dimer interface [polypeptide binding]; other site
585034012899	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
585034012900	dimer interface [polypeptide binding]; other site
585034012901	active site
585034012902	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
585034012903	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
585034012904	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
585034012905	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
585034012906	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
585034012907	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
585034012908	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034012909	putative substrate translocation pore; other site
585034012910	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034012911	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
585034012912	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034012913	dimer interface [polypeptide binding]; other site
585034012914	conserved gate region; other site
585034012915	putative PBP binding loops; other site
585034012916	ABC-ATPase subunit interface; other site
585034012917	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034012918	dimer interface [polypeptide binding]; other site
585034012919	conserved gate region; other site
585034012920	putative PBP binding loops; other site
585034012921	ABC-ATPase subunit interface; other site
585034012922	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
585034012923	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
585034012924	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
585034012925	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
585034012926	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
585034012927	Walker A/P-loop; other site
585034012928	ATP binding site [chemical binding]; other site
585034012929	Q-loop/lid; other site
585034012930	ABC transporter signature motif; other site
585034012931	Walker B; other site
585034012932	D-loop; other site
585034012933	H-loop/switch region; other site
585034012934	TOBE domain; Region: TOBE_2; pfam08402
585034012935	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
585034012936	trimer interface; other site
585034012937	sugar binding site [chemical binding]; other site
585034012938	maltose regulon periplasmic protein; Provisional; Region: PRK10564
585034012939	hypothetical protein; Validated; Region: PRK09718
585034012940	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
585034012941	SopA-like central domain; Region: SopA; pfam13981
585034012942	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
585034012943	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
585034012944	UbiA prenyltransferase family; Region: UbiA; pfam01040
585034012945	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
585034012946	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
585034012947	putative acyl-acceptor binding pocket; other site
585034012948	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
585034012949	LexA repressor; Validated; Region: PRK00215
585034012950	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
585034012951	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
585034012952	Catalytic site [active]
585034012953	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
585034012954	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
585034012955	hypothetical protein; Provisional; Region: PRK10428
585034012956	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
585034012957	metal binding site 2 [ion binding]; metal-binding site
585034012958	putative DNA binding helix; other site
585034012959	metal binding site 1 [ion binding]; metal-binding site
585034012960	dimer interface [polypeptide binding]; other site
585034012961	structural Zn2+ binding site [ion binding]; other site
585034012962	Protein of unknown function (DUF2713); Region: DUF2713; pfam10897
585034012963	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
585034012964	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
585034012965	FMN binding site [chemical binding]; other site
585034012966	active site
585034012967	catalytic residues [active]
585034012968	substrate binding site [chemical binding]; other site
585034012969	phage shock protein G; Reviewed; Region: pspG; PRK09459
585034012970	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
585034012971	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
585034012972	NADP binding site [chemical binding]; other site
585034012973	dimer interface [polypeptide binding]; other site
585034012974	replicative DNA helicase; Provisional; Region: PRK08006
585034012975	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
585034012976	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
585034012977	Walker A motif; other site
585034012978	ATP binding site [chemical binding]; other site
585034012979	Walker B motif; other site
585034012980	DNA binding loops [nucleotide binding]
585034012981	alanine racemase; Reviewed; Region: alr; PRK00053
585034012982	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
585034012983	active site
585034012984	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
585034012985	substrate binding site [chemical binding]; other site
585034012986	catalytic residues [active]
585034012987	dimer interface [polypeptide binding]; other site
585034012988	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
585034012989	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585034012990	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034012991	homodimer interface [polypeptide binding]; other site
585034012992	catalytic residue [active]
585034012993	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034012994	active site
585034012995	motif I; other site
585034012996	motif II; other site
585034012997	Uncharacterized protein family UPF0047; Region: UPF0047; cl00439
585034012998	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
585034012999	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
585034013000	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
585034013001	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
585034013002	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
585034013003	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
585034013004	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
585034013005	dimer interface [polypeptide binding]; other site
585034013006	ssDNA binding site [nucleotide binding]; other site
585034013007	tetramer (dimer of dimers) interface [polypeptide binding]; other site
585034013008	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
585034013009	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
585034013010	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
585034013011	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
585034013012	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
585034013013	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034013014	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
585034013015	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
585034013016	DNA binding residues [nucleotide binding]
585034013017	dimer interface [polypeptide binding]; other site
585034013018	[2Fe-2S] cluster binding site [ion binding]; other site
585034013019	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
585034013020	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
585034013021	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
585034013022	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
585034013023	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
585034013024	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
585034013025	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
585034013026	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
585034013027	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
585034013028	Na binding site [ion binding]; other site
585034013029	Predicted membrane protein [Function unknown]; Region: COG3162
585034013030	acetyl-CoA synthetase; Provisional; Region: PRK00174
585034013031	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
585034013032	active site
585034013033	CoA binding site [chemical binding]; other site
585034013034	acyl-activating enzyme (AAE) consensus motif; other site
585034013035	AMP binding site [chemical binding]; other site
585034013036	acetate binding site [chemical binding]; other site
585034013037	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
585034013038	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
585034013039	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
585034013040	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
585034013041	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
585034013042	heme lyase subunit NrfE; Provisional; Region: PRK10369
585034013043	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
585034013044	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
585034013045	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
585034013046	binding surface
585034013047	TPR motif; other site
585034013048	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
585034013049	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
585034013050	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
585034013051	Sel1-like repeats; Region: SEL1; smart00671
585034013052	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
585034013053	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
585034013054	[4Fe-4S] binding site [ion binding]; other site
585034013055	molybdopterin cofactor binding site; other site
585034013056	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
585034013057	molybdopterin cofactor binding site; other site
585034013058	putative outer membrane efflux protein MdtP; Provisional; Region: PRK09915
585034013059	multidrug efflux system protein MdtO; Provisional; Region: PRK11427
585034013060	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
585034013061	multidrug resistance protein MdtN; Provisional; Region: PRK10476
585034013062	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
585034013063	HlyD family secretion protein; Region: HlyD_3; pfam13437
585034013064	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
585034013065	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
585034013066	Ribose/Galactose Isomerase; Region: LacAB_rpiB; cl00485
585034013067	carbon-phosphorus lyase complex accessory protein; Provisional; Region: phnP; PRK11244
585034013068	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585034013069	Coenzyme A binding pocket [chemical binding]; other site
585034013070	ribose 1,5-bisphosphokinase; Provisional; Region: PRK10078
585034013071	AAA domain; Region: AAA_18; pfam13238
585034013072	active site
585034013073	phosphonate metabolism protein PhnM; Provisional; Region: PRK15446
585034013074	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
585034013075	PhnM is believed to be a subunit of the membrane associated C-P lyase complex. C-P lyase is thought to catalyze the direct cleavage of inactivated C-P bonds to yield inorganic phosphate and the corresponding hydrocarbons. It is responsible for cleavage...; Region: PhnM; cd01306
585034013076	active site
585034013077	ABC-type phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PhnL; COG4778
585034013078	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
585034013079	Walker A/P-loop; other site
585034013080	ATP binding site [chemical binding]; other site
585034013081	Q-loop/lid; other site
585034013082	ABC transporter signature motif; other site
585034013083	Walker B; other site
585034013084	D-loop; other site
585034013085	H-loop/switch region; other site
585034013086	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
585034013087	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
585034013088	Walker A/P-loop; other site
585034013089	ATP binding site [chemical binding]; other site
585034013090	Q-loop/lid; other site
585034013091	ABC transporter signature motif; other site
585034013092	Walker B; other site
585034013093	D-loop; other site
585034013094	H-loop/switch region; other site
585034013095	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
585034013096	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnJ; COG3627
585034013097	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnI; COG3626
585034013098	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnH; COG3625
585034013099	Phosphonate metabolism protein PhnG; Region: PhnG; pfam06754
585034013100	phosphonate metabolism transcriptional regulator PhnF; Provisional; Region: PRK10079
585034013101	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034013102	DNA-binding site [nucleotide binding]; DNA binding site
585034013103	UTRA domain; Region: UTRA; pfam07702
585034013104	ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism]; Region: COG3639
585034013105	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
585034013106	dimer interface [polypeptide binding]; other site
585034013107	conserved gate region; other site
585034013108	putative PBP binding loops; other site
585034013109	ABC-ATPase subunit interface; other site
585034013110	phosphonate ABC transporter, periplasmic phosphonate binding protein; Region: PhnD; TIGR03431
585034013111	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
585034013112	substrate binding pocket [chemical binding]; other site
585034013113	membrane-bound complex binding site; other site
585034013114	hinge residues; other site
585034013115	phosphonate/organophosphate ester transporter subunit; Provisional; Region: PRK09984
585034013116	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
585034013117	Walker A/P-loop; other site
585034013118	ATP binding site [chemical binding]; other site
585034013119	Q-loop/lid; other site
585034013120	ABC transporter signature motif; other site
585034013121	Walker B; other site
585034013122	D-loop; other site
585034013123	H-loop/switch region; other site
585034013124	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
585034013125	dimer interface [polypeptide binding]; other site
585034013126	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
585034013127	hypothetical protein; Provisional; Region: PRK10220
585034013128	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
585034013129	PhnA protein; Region: PhnA; pfam03831
585034013130	hypothetical protein; Provisional; Region: PRK09866
585034013131	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
585034013132	G1 box; other site
585034013133	GTP/Mg2+ binding site [chemical binding]; other site
585034013134	G2 box; other site
585034013135	Switch I region; other site
585034013136	G3 box; other site
585034013137	Switch II region; other site
585034013138	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
585034013139	G2 box; other site
585034013140	Switch I region; other site
585034013141	G3 box; other site
585034013142	Switch II region; other site
585034013143	G4 box; other site
585034013144	G5 box; other site
585034013145	YjcZ-like protein; Region: YjcZ; pfam13990
585034013146	proline/glycine betaine transporter; Provisional; Region: PRK10642
585034013147	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034013148	putative substrate translocation pore; other site
585034013149	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
585034013150	sensor protein BasS/PmrB; Provisional; Region: PRK10755
585034013151	HAMP domain; Region: HAMP; pfam00672
585034013152	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585034013153	dimer interface [polypeptide binding]; other site
585034013154	phosphorylation site [posttranslational modification]
585034013155	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034013156	ATP binding site [chemical binding]; other site
585034013157	Mg2+ binding site [ion binding]; other site
585034013158	G-X-G motif; other site
585034013159	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
585034013160	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034013161	active site
585034013162	phosphorylation site [posttranslational modification]
585034013163	intermolecular recognition site; other site
585034013164	dimerization interface [polypeptide binding]; other site
585034013165	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585034013166	DNA binding site [nucleotide binding]
585034013167	putative metal dependent hydrolase; Provisional; Region: PRK11598
585034013168	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
585034013169	Sulfatase; Region: Sulfatase; pfam00884
585034013170	arginine:agmatin antiporter; Provisional; Region: PRK10644
585034013171	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
585034013172	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034013173	arginine decarboxylase; Provisional; Region: PRK15029
585034013174	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
585034013175	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
585034013176	homodimer interface [polypeptide binding]; other site
585034013177	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034013178	catalytic residue [active]
585034013179	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
585034013180	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
585034013181	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034013182	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034013183	alpha-galactosidase; Provisional; Region: PRK15076
585034013184	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
585034013185	NAD binding site [chemical binding]; other site
585034013186	sugar binding site [chemical binding]; other site
585034013187	divalent metal binding site [ion binding]; other site
585034013188	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
585034013189	dimer interface [polypeptide binding]; other site
585034013190	melibiose:sodium symporter; Provisional; Region: PRK10429
585034013191	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
585034013192	hypothetical protein; Provisional; Region: PRK09867
585034013193	fumarate hydratase; Provisional; Region: PRK15389
585034013194	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
585034013195	Fumarase C-terminus; Region: Fumerase_C; pfam05683
585034013196	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
585034013197	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
585034013198	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
585034013199	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034013200	active site
585034013201	phosphorylation site [posttranslational modification]
585034013202	intermolecular recognition site; other site
585034013203	dimerization interface [polypeptide binding]; other site
585034013204	Transcriptional regulator; Region: CitT; pfam12431
585034013205	sensory histidine kinase DcuS; Provisional; Region: PRK11086
585034013206	PAS domain; Region: PAS; smart00091
585034013207	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034013208	ATP binding site [chemical binding]; other site
585034013209	Mg2+ binding site [ion binding]; other site
585034013210	G-X-G motif; other site
585034013211	Uncharacterized conserved protein [Function unknown]; Region: COG3592
585034013212	Predicted acetyltransferase [General function prediction only]; Region: COG2388
585034013213	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
585034013214	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
585034013215	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
585034013216	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
585034013217	dimer interface [polypeptide binding]; other site
585034013218	putative anticodon binding site; other site
585034013219	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
585034013220	motif 1; other site
585034013221	active site
585034013222	motif 2; other site
585034013223	motif 3; other site
585034013224	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
585034013225	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034013226	putative substrate translocation pore; other site
585034013227	POT family; Region: PTR2; pfam00854
585034013228	lysine decarboxylase CadA; Provisional; Region: PRK15400
585034013229	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
585034013230	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
585034013231	homodimer interface [polypeptide binding]; other site
585034013232	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034013233	catalytic residue [active]
585034013234	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
585034013235	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
585034013236	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
585034013237	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585034013238	DNA binding site [nucleotide binding]
585034013239	putative transcriptional regulator; Provisional; Region: PRK11640
585034013240	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585034013241	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
585034013242	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
585034013243	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
585034013244	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
585034013245	DsbD alpha interface [polypeptide binding]; other site
585034013246	catalytic residues [active]
585034013247	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
585034013248	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
585034013249	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
585034013250	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
585034013251	Aspartase; Region: Aspartase; cd01357
585034013252	active sites [active]
585034013253	tetramer interface [polypeptide binding]; other site
585034013254	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
585034013255	putative transporter; Provisional; Region: PRK11021
585034013256	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
585034013257	oligomerisation interface [polypeptide binding]; other site
585034013258	mobile loop; other site
585034013259	roof hairpin; other site
585034013260	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
585034013261	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
585034013262	ring oligomerisation interface [polypeptide binding]; other site
585034013263	ATP/Mg binding site [chemical binding]; other site
585034013264	stacking interactions; other site
585034013265	hinge regions; other site
585034013266	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
585034013267	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
585034013268	Transposase; Region: DEDD_Tnp_IS110; pfam01548
585034013269	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
585034013270	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
585034013271	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585034013272	FeS/SAM binding site; other site
585034013273	elongation factor P; Validated; Region: PRK00529
585034013274	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
585034013275	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
585034013276	RNA binding site [nucleotide binding]; other site
585034013277	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
585034013278	RNA binding site [nucleotide binding]; other site
585034013279	entericidin A; Provisional; Region: PRK09810
585034013280	multidrug efflux system protein; Provisional; Region: PRK11431
585034013281	Bacterial lipocalin [Cell envelope biogenesis, outer membrane]; Region: Blc; COG3040
585034013282	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
585034013283	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
585034013284	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
585034013285	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
585034013286	Iron-sulfur protein interface; other site
585034013287	proximal quinone binding site [chemical binding]; other site
585034013288	C-subunit interface; other site
585034013289	distal quinone binding site; other site
585034013290	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
585034013291	D-subunit interface [polypeptide binding]; other site
585034013292	Iron-sulfur protein interface; other site
585034013293	proximal quinone binding site [chemical binding]; other site
585034013294	distal quinone binding site [chemical binding]; other site
585034013295	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
585034013296	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
585034013297	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
585034013298	L-aspartate oxidase; Provisional; Region: PRK06175
585034013299	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
585034013300	poxB regulator PoxA; Provisional; Region: PRK09350
585034013301	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
585034013302	motif 1; other site
585034013303	dimer interface [polypeptide binding]; other site
585034013304	active site
585034013305	motif 2; other site
585034013306	motif 3; other site
585034013307	inner membrane transporter YjeM; Provisional; Region: PRK15238
585034013308	putative mechanosensitive channel protein; Provisional; Region: PRK10929
585034013309	linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated...; Region: H15; cl00073
585034013310	DNA-binding site [nucleotide binding]; DNA binding site
585034013311	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
585034013312	Mechanosensitive ion channel; Region: MS_channel; pfam00924
585034013313	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
585034013314	GTPase RsgA; Reviewed; Region: PRK12288
585034013315	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
585034013316	RNA binding site [nucleotide binding]; other site
585034013317	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
585034013318	GTPase/Zn-binding domain interface [polypeptide binding]; other site
585034013319	GTP/Mg2+ binding site [chemical binding]; other site
585034013320	G4 box; other site
585034013321	G5 box; other site
585034013322	G1 box; other site
585034013323	Switch I region; other site
585034013324	G2 box; other site
585034013325	G3 box; other site
585034013326	Switch II region; other site
585034013327	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
585034013328	catalytic site [active]
585034013329	putative active site [active]
585034013330	putative substrate binding site [chemical binding]; other site
585034013331	dimer interface [polypeptide binding]; other site
585034013332	epoxyqueuosine reductase; Region: TIGR00276
585034013333	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
585034013334	putative carbohydrate kinase; Provisional; Region: PRK10565
585034013335	yjeF N-terminal region; Region: yjeF_nterm; TIGR00197
585034013336	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
585034013337	putative substrate binding site [chemical binding]; other site
585034013338	putative ATP binding site [chemical binding]; other site
585034013339	ADP-binding protein; Provisional; Region: PRK10646
585034013340	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
585034013341	AMIN domain; Region: AMIN; pfam11741
585034013342	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
585034013343	active site
585034013344	metal binding site [ion binding]; metal-binding site
585034013345	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
585034013346	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034013347	ATP binding site [chemical binding]; other site
585034013348	Mg2+ binding site [ion binding]; other site
585034013349	G-X-G motif; other site
585034013350	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
585034013351	ATP binding site [chemical binding]; other site
585034013352	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
585034013353	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
585034013354	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
585034013355	bacterial Hfq-like; Region: Hfq; cd01716
585034013356	hexamer interface [polypeptide binding]; other site
585034013357	Sm1 motif; other site
585034013358	RNA binding site [nucleotide binding]; other site
585034013359	Sm2 motif; other site
585034013360	GTPase HflX; Provisional; Region: PRK11058
585034013361	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
585034013362	HflX GTPase family; Region: HflX; cd01878
585034013363	G1 box; other site
585034013364	GTP/Mg2+ binding site [chemical binding]; other site
585034013365	Switch I region; other site
585034013366	G2 box; other site
585034013367	G3 box; other site
585034013368	Switch II region; other site
585034013369	G4 box; other site
585034013370	G5 box; other site
585034013371	FtsH protease regulator HflK; Provisional; Region: PRK10930
585034013372	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
585034013373	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
585034013374	FtsH protease regulator HflC; Provisional; Region: PRK11029
585034013375	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
585034013376	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
585034013377	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
585034013378	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
585034013379	GDP-binding site [chemical binding]; other site
585034013380	ACT binding site; other site
585034013381	IMP binding site; other site
585034013382	Predicted transcriptional regulator [Transcription]; Region: COG1959
585034013383	transcriptional repressor NsrR; Provisional; Region: PRK11014
585034013384	exoribonuclease R; Provisional; Region: PRK11642
585034013385	Ribonuclease R winged-helix domain; Region: HTH_12; pfam08461
585034013386	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
585034013387	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
585034013388	RNB domain; Region: RNB; pfam00773
585034013389	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
585034013390	RNA binding site [nucleotide binding]; other site
585034013391	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
585034013392	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
585034013393	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
585034013394	Uncharacterized protein conserved in bacteria (DUF2170); Region: DUF2170; cl01551
585034013395	PspA/IM30 family; Region: PspA_IM30; pfam04012
585034013396	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
585034013397	Predicted membrane protein [Function unknown]; Region: COG3766
585034013398	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
585034013399	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
585034013400	Predicted integral membrane protein [Function unknown]; Region: COG5463
585034013401	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
585034013402	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
585034013403	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
585034013404	FAD binding site [chemical binding]; other site
585034013405	substrate binding site [chemical binding]; other site
585034013406	catalytic residues [active]
585034013407	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
585034013408	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
585034013409	esterase; Provisional; Region: PRK10566
585034013410	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
585034013411	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
585034013412	transcriptional repressor UlaR; Provisional; Region: PRK13509
585034013413	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
585034013414	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
585034013415	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
585034013416	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
585034013417	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
585034013418	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
585034013419	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
585034013420	active site
585034013421	P-loop; other site
585034013422	phosphorylation site [posttranslational modification]
585034013423	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
585034013424	active site
585034013425	phosphorylation site [posttranslational modification]
585034013426	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
585034013427	active site
585034013428	dimer interface [polypeptide binding]; other site
585034013429	magnesium binding site [ion binding]; other site
585034013430	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
585034013431	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
585034013432	AP (apurinic/apyrimidinic) site pocket; other site
585034013433	DNA interaction; other site
585034013434	Metal-binding active site; metal-binding site
585034013435	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
585034013436	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
585034013437	intersubunit interface [polypeptide binding]; other site
585034013438	active site
585034013439	Zn2+ binding site [ion binding]; other site
585034013440	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
585034013441	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
585034013442	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
585034013443	dimer interface [polypeptide binding]; other site
585034013444	ssDNA binding site [nucleotide binding]; other site
585034013445	tetramer (dimer of dimers) interface [polypeptide binding]; other site
585034013446	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
585034013447	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
585034013448	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
585034013449	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
585034013450	Protein of unknown function (DUF2686); Region: DUF2686; pfam10887
585034013451	Transposase IS200 like; Region: Y1_Tnp; pfam01797
585034013452	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
585034013453	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
585034013454	Probable transposase; Region: OrfB_IS605; pfam01385
585034013455	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
585034013456	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
585034013457	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
585034013458	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
585034013459	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
585034013460	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
585034013461	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
585034013462	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
585034013463	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
585034013464	Hemerythrin-like domain; Region: Hr-like; cd12108
585034013465	Fe binding site [ion binding]; other site
585034013466	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
585034013467	EamA-like transporter family; Region: EamA; pfam00892
585034013468	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
585034013469	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
585034013470	NADP binding site [chemical binding]; other site
585034013471	Predicted transcriptional regulators [Transcription]; Region: COG1733
585034013472	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
585034013473	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
585034013474	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
585034013475	active site
585034013476	metal binding site [ion binding]; metal-binding site
585034013477	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
585034013478	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
585034013479	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
585034013480	active site
585034013481	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
585034013482	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
585034013483	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
585034013484	Domain of unknown function DUF21; Region: DUF21; pfam01595
585034013485	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
585034013486	Transporter associated domain; Region: CorC_HlyC; smart01091
585034013487	methionine sulfoxide reductase A; Provisional; Region: PRK00058
585034013488	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
585034013489	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
585034013490	Surface antigen; Region: Bac_surface_Ag; pfam01103
585034013491	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
585034013492	Family of unknown function (DUF490); Region: DUF490; pfam04357
585034013493	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
585034013494	putative active site pocket [active]
585034013495	dimerization interface [polypeptide binding]; other site
585034013496	putative catalytic residue [active]
585034013497	antitoxin ChpS; Provisional; Region: PRK11347
585034013498	toxin ChpB; Provisional; Region: PRK09812
585034013499	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
585034013500	dimer interface [polypeptide binding]; other site
585034013501	substrate binding site [chemical binding]; other site
585034013502	metal binding sites [ion binding]; metal-binding site
585034013503	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
585034013504	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
585034013505	putative ligand binding site [chemical binding]; other site
585034013506	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
585034013507	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
585034013508	Walker A/P-loop; other site
585034013509	ATP binding site [chemical binding]; other site
585034013510	Q-loop/lid; other site
585034013511	ABC transporter signature motif; other site
585034013512	Walker B; other site
585034013513	D-loop; other site
585034013514	H-loop/switch region; other site
585034013515	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
585034013516	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585034013517	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585034013518	TM-ABC transporter signature motif; other site
585034013519	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
585034013520	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
585034013521	TM-ABC transporter signature motif; other site
585034013522	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
585034013523	AMP binding site [chemical binding]; other site
585034013524	metal binding site [ion binding]; metal-binding site
585034013525	active site
585034013526	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
585034013527	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
585034013528	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
585034013529	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
585034013530	hypothetical protein; Provisional; Region: PRK05255
585034013531	peptidase PmbA; Provisional; Region: PRK11040
585034013532	cytochrome b562; Provisional; Region: PRK15058
585034013533	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
585034013534	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585034013535	FeS/SAM binding site; other site
585034013536	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
585034013537	ATP cone domain; Region: ATP-cone; pfam03477
585034013538	Class III ribonucleotide reductase; Region: RNR_III; cd01675
585034013539	effector binding site; other site
585034013540	active site
585034013541	Zn binding site [ion binding]; other site
585034013542	glycine loop; other site
585034013543	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
585034013544	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
585034013545	Ca binding site [ion binding]; other site
585034013546	active site
585034013547	catalytic site [active]
585034013548	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
585034013549	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
585034013550	active site turn [active]
585034013551	phosphorylation site [posttranslational modification]
585034013552	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
585034013553	trehalose repressor; Provisional; Region: treR; PRK09492
585034013554	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
585034013555	DNA binding site [nucleotide binding]
585034013556	domain linker motif; other site
585034013557	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
585034013558	dimerization interface [polypeptide binding]; other site
585034013559	ligand binding site [chemical binding]; other site
585034013560	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
585034013561	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
585034013562	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
585034013563	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
585034013564	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034013565	motif II; other site
585034013566	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
585034013567	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
585034013568	homotrimer interaction site [polypeptide binding]; other site
585034013569	putative active site [active]
585034013570	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
585034013571	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
585034013572	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
585034013573	aspartate carbamoyltransferase; Region: asp_carb_tr; TIGR00670
585034013574	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
585034013575	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
585034013576	PyrBI operon leader peptide; Region: PyrBI_leader; pfam08052
585034013577	YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198
585034013578	homotrimer interaction site [polypeptide binding]; other site
585034013579	putative active site [active]
585034013580	oxidoreductase; Provisional; Region: PRK12742
585034013581	classical (c) SDRs; Region: SDR_c; cd05233
585034013582	NAD(P) binding site [chemical binding]; other site
585034013583	active site
585034013584	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
585034013585	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
585034013586	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
585034013587	fragment of conserved hypothetical protein (part 1);Evidence 7 : Gene remnant
585034013588	fragment of conserved hypothetical protein (part 2);Evidence 7 : Gene remnant
585034013589	fragment of conserved hypothetical protein (part 3);Evidence 7 : Gene remnant
585034013590	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
585034013591	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
585034013592	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
585034013593	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
585034013594	RNase E inhibitor protein; Provisional; Region: PRK11191
585034013595	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
585034013596	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585034013597	Coenzyme A binding pocket [chemical binding]; other site
585034013598	Predicted membrane protein [Function unknown]; Region: COG4269
585034013599	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
585034013600	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
585034013601	HIGH motif; other site
585034013602	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
585034013603	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
585034013604	active site
585034013605	KMSKS motif; other site
585034013606	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
585034013607	tRNA binding surface [nucleotide binding]; other site
585034013608	anticodon binding site; other site
585034013609	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
585034013610	DNA polymerase III subunit chi; Validated; Region: PRK05728
585034013611	multifunctional aminopeptidase A; Provisional; Region: PRK00913
585034013612	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
585034013613	interface (dimer of trimers) [polypeptide binding]; other site
585034013614	Substrate-binding/catalytic site; other site
585034013615	Zn-binding sites [ion binding]; other site
585034013616	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
585034013617	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
585034013618	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
585034013619	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
585034013620	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
585034013621	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
585034013622	Walker A motif; other site
585034013623	ATP binding site [chemical binding]; other site
585034013624	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
585034013625	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
585034013626	putative NAD(P) binding site [chemical binding]; other site
585034013627	putative substrate binding site [chemical binding]; other site
585034013628	catalytic Zn binding site [ion binding]; other site
585034013629	structural Zn binding site [ion binding]; other site
585034013630	dimer interface [polypeptide binding]; other site
585034013631	integrase; Provisional; Region: PRK09692
585034013632	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
585034013633	active site
585034013634	Int/Topo IB signature motif; other site
585034013635	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
585034013636	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
585034013637	cofactor binding site; other site
585034013638	DNA binding site [nucleotide binding]
585034013639	substrate interaction site [chemical binding]; other site
585034013640	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
585034013641	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
585034013642	active site
585034013643	catalytic residues [active]
585034013644	DNA binding site [nucleotide binding]
585034013645	Int/Topo IB signature motif; other site
585034013646	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
585034013647	active site
585034013648	catalytic residues [active]
585034013649	DNA binding site [nucleotide binding]
585034013650	Int/Topo IB signature motif; other site
585034013651	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4688
585034013652	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
585034013653	Abi-like protein; Region: Abi_2; pfam07751
585034013654	Uncharacterized conserved protein [Function unknown]; Region: COG4938
585034013655	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585034013656	Walker A/P-loop; other site
585034013657	ATP binding site [chemical binding]; other site
585034013658	Protein of unknown function (DUF3696); Region: DUF3696; pfam12476
585034013659	Protein of unknown function DUF262; Region: DUF262; pfam03235
585034013660	Domain of unknown function (DUF303); Region: DUF303; pfam03629
585034013661	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
585034013662	Kelch motif; Region: Kelch_1; pfam01344
585034013663	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
585034013664	FimB and FimE and related proteins, DNA breaking-rejoining enzymes, integrase/recombinases, catalytic domain. This CD includes those proteins similar to E.coli FimE and FimB regulatory proteins and Proteus mirabilis MrpI; Region: INT_FimBE_C; cd01197
585034013665	Int/Topo IB signature motif; other site
585034013666	FimB and FimE and related proteins, DNA breaking-rejoining enzymes, integrase/recombinases, catalytic domain. This CD includes those proteins similar to E.coli FimE and FimB regulatory proteins and Proteus mirabilis MrpI; Region: INT_FimBE_C; cd01197
585034013667	Int/Topo IB signature motif; other site
585034013668	Fimbrial protein; Region: Fimbrial; cl01416
585034013669	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
585034013670	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
585034013671	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
585034013672	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
585034013673	outer membrane usher protein; Provisional; Region: PRK15193
585034013674	PapC N-terminal domain; Region: PapC_N; pfam13954
585034013675	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
585034013676	PapC C-terminal domain; Region: PapC_C; pfam13953
585034013677	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
585034013678	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
585034013679	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
585034013680	mannosyl binding site [chemical binding]; other site
585034013681	Fimbrial protein; Region: Fimbrial; pfam00419
585034013682	fructuronate transporter; Provisional; Region: PRK10034
585034013683	gluconate transporter; Region: gntP; TIGR00791
585034013684	mannonate dehydratase; Region: uxuA; TIGR00695
585034013685	mannonate dehydratase; Provisional; Region: PRK03906
585034013686	D-mannonate oxidoreductase; Provisional; Region: PRK15037
585034013687	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
585034013688	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
585034013689	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
585034013690	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034013691	DNA-binding site [nucleotide binding]; DNA binding site
585034013692	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
585034013693	Protein of unknown function (DUF2686); Region: DUF2686; pfam10887
585034013694	Glycine/serine hydroxymethyltransferase [Amino acid transport and metabolism]; Region: GlyA; COG0112
585034013695	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
585034013696	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
585034013697	cell density-dependent motility repressor; Provisional; Region: PRK10082
585034013698	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
585034013699	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
585034013700	Isoaspartyl dipeptidase hydrolyzes the beta-L-isoaspartyl linkages in dipeptides, as part of the degradative pathway to eliminate proteins with beta-L-isoaspartyl peptide bonds, bonds whereby the beta-group of an aspartate forms the peptide link with the...; Region: Isoaspartyl-dipeptidase; cd01308
585034013701	isoaspartyl dipeptidase IadA; Region: isoAsp_dipep; TIGR01975
585034013702	dimer interface [polypeptide binding]; other site
585034013703	active site
585034013704	hypothetical protein; Provisional; Region: PRK10519
585034013705	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
585034013706	Nucleoside recognition; Region: Gate; pfam07670
585034013707	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
585034013708	RNA 2'-phosphotransferase; Reviewed; Region: PRK00819
585034013709	Protein of unknown function (DUF1228); Region: DUF1228; pfam06779
585034013710	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
585034013711	SdiA-regulated; Region: SdiA-regulated; cd09971
585034013712	putative active site [active]
585034013713	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
585034013714	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
585034013715	CoA-substrate-specific enzyme activase, putative; Region: CoA_E_activ; TIGR00241
585034013716	Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB [Amino acid transport and metabolism]; Region: HgdB; COG1775
585034013717	benzoyl-CoA reductase, subunit C; Region: benz_CoA_red_C; TIGR02263
585034013718	Predicted membrane protein [Function unknown]; Region: COG2733
585034013719	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
585034013720	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034013721	putative substrate translocation pore; other site
585034013722	putative transposase; Provisional; Region: PRK09857
585034013723	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
585034013724	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
585034013725	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034013726	DNA-binding site [nucleotide binding]; DNA binding site
585034013727	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
585034013728	pyridoxal 5'-phosphate binding site [chemical binding]; other site
585034013729	homodimer interface [polypeptide binding]; other site
585034013730	catalytic residue [active]
585034013731	Uncharacterized conserved small protein [Function unknown]; Region: COG5457
585034013732	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
585034013733	Penicillin G acylase (PGA) is the key enzyme in the industrial production of beta-lactam antibiotics. PGA hydrolyzes the side chain of penicillin G and related beta-lactam antibiotics releasing 6-amino penicillanic acid (6-APA), a building block in the...; Region: Ntn_PGA; cd03748
585034013734	Penicillin amidase; Region: Penicil_amidase; pfam01804
585034013735	active site
585034013736	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
585034013737	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
585034013738	P-loop, Walker A motif; other site
585034013739	Base recognition motif; other site
585034013740	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
585034013741	Uncharacterized small protein [Function unknown]; Region: COG2879
585034013742	carbon starvation protein A; Provisional; Region: PRK15015
585034013743	Carbon starvation protein CstA; Region: CstA; pfam02554
585034013744	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
585034013745	4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional; Region: hpaC; PRK15486
585034013746	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
585034013747	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
585034013748	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
585034013749	Cupin domain; Region: Cupin_2; pfam07883
585034013750	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034013751	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034013752	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
585034013753	putative substrate translocation pore; other site
585034013754	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
585034013755	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
585034013756	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
585034013757	putative substrate binding pocket [chemical binding]; other site
585034013758	trimer interface [polypeptide binding]; other site
585034013759	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
585034013760	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
585034013761	putative active site [active]
585034013762	putative metal binding site [ion binding]; other site
585034013763	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
585034013764	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
585034013765	NAD binding site [chemical binding]; other site
585034013766	catalytic residues [active]
585034013767	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional; Region: PRK15203
585034013768	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit; Region: HpaG-N-term; TIGR02305
585034013769	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
585034013770	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
585034013771	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
585034013772	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
585034013773	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
585034013774	dimer interface [polypeptide binding]; other site
585034013775	ligand binding site [chemical binding]; other site
585034013776	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585034013777	dimerization interface [polypeptide binding]; other site
585034013778	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
585034013779	dimer interface [polypeptide binding]; other site
585034013780	putative CheW interface [polypeptide binding]; other site
585034013781	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
585034013782	D-galactonate transporter; Region: 2A0114; TIGR00893
585034013783	putative substrate translocation pore; other site
585034013784	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
585034013785	DNA-binding site [nucleotide binding]; DNA binding site
585034013786	Transcriptional regulators [Transcription]; Region: GntR; COG1802
585034013787	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
585034013788	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
585034013789	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
585034013790	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
585034013791	putative NAD(P) binding site [chemical binding]; other site
585034013792	catalytic Zn binding site [ion binding]; other site
585034013793	structural Zn binding site [ion binding]; other site
585034013794	phosphoglycerol transferase I; Provisional; Region: PRK03776
585034013795	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
585034013796	hypothetical protein; Provisional; Region: PRK11667
585034013797	DNA replication protein DnaC; Validated; Region: PRK07952
585034013798	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
585034013799	Walker A motif; other site
585034013800	ATP binding site [chemical binding]; other site
585034013801	Walker B motif; other site
585034013802	primosomal protein DnaI; Provisional; Region: PRK02854
585034013803	hypothetical protein; Provisional; Region: PRK09917
585034013804	Uncharacterized conserved protein [Function unknown]; Region: COG2966
585034013805	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
585034013806	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
585034013807	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585034013808	DNA binding residues [nucleotide binding]
585034013809	dimerization interface [polypeptide binding]; other site
585034013810	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
585034013811	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
585034013812	DNA binding residues [nucleotide binding]
585034013813	dimerization interface [polypeptide binding]; other site
585034013814	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
585034013815	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
585034013816	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
585034013817	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
585034013818	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
585034013819	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
585034013820	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
585034013821	S-adenosylmethionine binding site [chemical binding]; other site
585034013822	DNA polymerase III, psi subunit [DNA replication, recombination, and repair]; Region: HolD; COG3050
585034013823	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
585034013824	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
585034013825	Coenzyme A binding pocket [chemical binding]; other site
585034013826	dUMP phosphatase; Provisional; Region: PRK09449
585034013827	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034013828	motif II; other site
585034013829	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
585034013830	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
585034013831	G1 box; other site
585034013832	putative GEF interaction site [polypeptide binding]; other site
585034013833	GTP/Mg2+ binding site [chemical binding]; other site
585034013834	Switch I region; other site
585034013835	G2 box; other site
585034013836	G3 box; other site
585034013837	Switch II region; other site
585034013838	G4 box; other site
585034013839	G5 box; other site
585034013840	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
585034013841	periplasmic protein; Provisional; Region: PRK10568
585034013842	BON domain; Region: BON; pfam04972
585034013843	BON domain; Region: BON; pfam04972
585034013844	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
585034013845	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
585034013846	active site
585034013847	nucleophile elbow; other site
585034013848	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
585034013849	active site
585034013850	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
585034013851	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
585034013852	FeS/SAM binding site; other site
585034013853	hypothetical protein; Provisional; Region: PRK10977
585034013854	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
585034013855	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
585034013856	intersubunit interface [polypeptide binding]; other site
585034013857	active site
585034013858	catalytic residue [active]
585034013859	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
585034013860	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
585034013861	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
585034013862	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
585034013863	phosphopentomutase; Provisional; Region: PRK05362
585034013864	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
585034013865	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
585034013866	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
585034013867	fragment of conserved hypothetical protein, putative transcriptionnal regulator (partial);Evidence 7 : Gene remnant
585034013868	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
585034013869	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
585034013870	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
585034013871	hypothetical protein; Provisional; Region: PRK11246
585034013872	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
585034013873	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
585034013874	motif II; other site
585034013875	DNA repair protein RadA; Region: sms; TIGR00416
585034013876	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
585034013877	Walker A motif/ATP binding site; other site
585034013878	ATP binding site [chemical binding]; other site
585034013879	Walker B motif; other site
585034013880	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
585034013881	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
585034013882	non-specific DNA binding site [nucleotide binding]; other site
585034013883	salt bridge; other site
585034013884	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
585034013885	sequence-specific DNA binding site [nucleotide binding]; other site
585034013886	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
585034013887	active site
585034013888	(T/H)XGH motif; other site
585034013889	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
585034013890	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
585034013891	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
585034013892	Walker A/P-loop; other site
585034013893	ATP binding site [chemical binding]; other site
585034013894	Q-loop/lid; other site
585034013895	ABC transporter signature motif; other site
585034013896	Walker B; other site
585034013897	D-loop; other site
585034013898	H-loop/switch region; other site
585034013899	ABC transporter; Region: ABC_tran_2; pfam12848
585034013900	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
585034013901	lytic murein transglycosylase; Provisional; Region: PRK11619
585034013902	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
585034013903	N-acetyl-D-glucosamine binding site [chemical binding]; other site
585034013904	catalytic residue [active]
585034013905	Trp operon repressor; Provisional; Region: PRK01381
585034013906	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
585034013907	Transposase; Region: DEDD_Tnp_IS110; pfam01548
585034013908	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
585034013909	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
585034013910	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
585034013911	catalytic core [active]
585034013912	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
585034013913	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
585034013914	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
585034013915	hypothetical protein; Provisional; Region: PRK10756
585034013916	CreA protein; Region: CreA; pfam05981
585034013917	DNA-binding response regulator CreB; Provisional; Region: PRK11083
585034013918	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034013919	active site
585034013920	phosphorylation site [posttranslational modification]
585034013921	intermolecular recognition site; other site
585034013922	dimerization interface [polypeptide binding]; other site
585034013923	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585034013924	DNA binding site [nucleotide binding]
585034013925	sensory histidine kinase CreC; Provisional; Region: PRK11100
585034013926	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
585034013927	dimerization interface [polypeptide binding]; other site
585034013928	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
585034013929	dimer interface [polypeptide binding]; other site
585034013930	phosphorylation site [posttranslational modification]
585034013931	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
585034013932	ATP binding site [chemical binding]; other site
585034013933	Mg2+ binding site [ion binding]; other site
585034013934	G-X-G motif; other site
585034013935	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
585034013936	two-component response regulator; Provisional; Region: PRK11173
585034013937	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
585034013938	active site
585034013939	phosphorylation site [posttranslational modification]
585034013940	intermolecular recognition site; other site
585034013941	dimerization interface [polypeptide binding]; other site
585034013942	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
585034013943	DNA binding site [nucleotide binding]
585034013944	putative RNA methyltransferase; Provisional; Region: PRK10433
585034013945	RNA methyltransferase, TrmH family, group 1; Region: rRNA_methyl_1; TIGR00050