-- dump date   	20140619_082941
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
595495000001	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
595495000002	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
595495000003	putative catalytic residues [active]
595495000004	putative nucleotide binding site [chemical binding]; other site
595495000005	putative aspartate binding site [chemical binding]; other site
595495000006	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
595495000007	dimer interface [polypeptide binding]; other site
595495000008	putative threonine allosteric regulatory site; other site
595495000009	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
595495000010	putative threonine allosteric regulatory site; other site
595495000011	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
595495000012	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
595495000013	homoserine kinase; Region: thrB; TIGR00191
595495000014	Protein of unknown function; Region: YhfT; pfam10797
595495000015	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
595495000016	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
595495000017	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
595495000018	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495000019	catalytic residue [active]
595495000020	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
595495000021	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
595495000022	Transposase; Region: DEDD_Tnp_IS110; pfam01548
595495000023	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
595495000024	hypothetical protein; Validated; Region: PRK02101
595495000025	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
595495000026	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
595495000027	transaldolase-like protein; Provisional; Region: PTZ00411
595495000028	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
595495000029	active site
595495000030	dimer interface [polypeptide binding]; other site
595495000031	catalytic residue [active]
595495000032	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
595495000033	MPT binding site; other site
595495000034	trimer interface [polypeptide binding]; other site
595495000035	hypothetical protein; Provisional; Region: PRK10659
595495000036	hypothetical protein; Provisional; Region: PRK10236
595495000037	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
595495000038	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
595495000039	hypothetical protein; Provisional; Region: PRK10154
595495000040	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
595495000041	Nucleotide-binding domain of human HSPA9, Escherichia coli DnaK, and similar proteins; Region: HSPA9-like_NBD; cd11733
595495000042	nucleotide binding site [chemical binding]; other site
595495000043	NEF interaction site [polypeptide binding]; other site
595495000044	SBD interface [polypeptide binding]; other site
595495000045	chaperone protein DnaJ; Provisional; Region: PRK10767
595495000046	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
595495000047	HSP70 interaction site [polypeptide binding]; other site
595495000048	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
595495000049	substrate binding site [polypeptide binding]; other site
595495000050	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
595495000051	Zn binding sites [ion binding]; other site
595495000052	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
595495000053	dimer interface [polypeptide binding]; other site
595495000054	Hok/gef family; Region: HOK_GEF; pfam01848
595495000055	Hok/gef family; Region: HOK_GEF; pfam01848
595495000056	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
595495000057	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
595495000058	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495000059	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
595495000060	putative dimerization interface [polypeptide binding]; other site
595495000061	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
595495000062	PapC C-terminal domain; Region: PapC_C; pfam13953
595495000063	potential frameshift: common BLAST hit: gi|260853232|ref|YP_003227123.1| T3SS effector-like protein EspX-homolog
595495000064	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
595495000065	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
595495000066	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
595495000067	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
595495000068	active site
595495000069	Riboflavin kinase; Region: Flavokinase; smart00904
595495000070	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
595495000071	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
595495000072	HIGH motif; other site
595495000073	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
595495000074	active site
595495000075	KMSKS motif; other site
595495000076	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
595495000077	tRNA binding surface [nucleotide binding]; other site
595495000078	anticodon binding site; other site
595495000079	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
595495000080	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
595495000081	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
595495000082	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
595495000083	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
595495000084	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
595495000085	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
595495000086	active site
595495000087	tetramer interface [polypeptide binding]; other site
595495000088	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
595495000089	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
595495000090	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
595495000091	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
595495000092	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
595495000093	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
595495000094	catalytic site [active]
595495000095	subunit interface [polypeptide binding]; other site
595495000096	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
595495000097	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
595495000098	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
595495000099	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
595495000100	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
595495000101	ATP-grasp domain; Region: ATP-grasp_4; cl17255
595495000102	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
595495000103	IMP binding site; other site
595495000104	dimer interface [polypeptide binding]; other site
595495000105	interdomain contacts; other site
595495000106	partial ornithine binding site; other site
595495000107	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
595495000108	carnitine operon protein CaiE; Provisional; Region: PRK13627
595495000109	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
595495000110	putative trimer interface [polypeptide binding]; other site
595495000111	putative metal binding site [ion binding]; other site
595495000112	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
595495000113	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
595495000114	substrate binding site [chemical binding]; other site
595495000115	oxyanion hole (OAH) forming residues; other site
595495000116	trimer interface [polypeptide binding]; other site
595495000117	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
595495000118	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
595495000119	acyl-activating enzyme (AAE) consensus motif; other site
595495000120	putative AMP binding site [chemical binding]; other site
595495000121	putative active site [active]
595495000122	putative CoA binding site [chemical binding]; other site
595495000123	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
595495000124	CoA-transferase family III; Region: CoA_transf_3; pfam02515
595495000125	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
595495000126	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
595495000127	active site
595495000128	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
595495000129	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
595495000130	Ligand binding site [chemical binding]; other site
595495000131	Electron transfer flavoprotein domain; Region: ETF; pfam01012
595495000132	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
595495000133	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF; cd01985
595495000134	Ligand binding site [chemical binding]; other site
595495000135	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
595495000136	putative oxidoreductase FixC; Provisional; Region: PRK10157
595495000137	ferredoxin-like protein FixX; Provisional; Region: PRK15449
595495000138	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495000139	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
595495000140	putative substrate translocation pore; other site
595495000141	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
595495000142	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
595495000143	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
595495000144	TrkA-N domain; Region: TrkA_N; pfam02254
595495000145	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
595495000146	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
595495000147	folate binding site [chemical binding]; other site
595495000148	NADP+ binding site [chemical binding]; other site
595495000149	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
595495000150	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
595495000151	active site
595495000152	metal binding site [ion binding]; metal-binding site
595495000153	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
595495000154	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
595495000155	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
595495000156	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
595495000157	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
595495000158	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
595495000159	SurA N-terminal domain; Region: SurA_N; pfam09312
595495000160	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
595495000161	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
595495000162	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
595495000163	OstA-like protein; Region: OstA; pfam03968
595495000164	Organic solvent tolerance protein; Region: OstA_C; pfam04453
595495000165	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
595495000166	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
595495000167	putative metal binding site [ion binding]; other site
595495000168	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
595495000169	HSP70 interaction site [polypeptide binding]; other site
595495000170	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
595495000171	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
595495000172	active site
595495000173	ATP-dependent helicase HepA; Validated; Region: PRK04914
595495000174	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
595495000175	ATP binding site [chemical binding]; other site
595495000176	putative Mg++ binding site [ion binding]; other site
595495000177	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
595495000178	nucleotide binding region [chemical binding]; other site
595495000179	ATP-binding site [chemical binding]; other site
595495000180	DNA polymerase II; Reviewed; Region: PRK05762
595495000181	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
595495000182	active site
595495000183	catalytic site [active]
595495000184	substrate binding site [chemical binding]; other site
595495000185	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
595495000186	active site
595495000187	metal-binding site
595495000188	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
595495000189	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
595495000190	intersubunit interface [polypeptide binding]; other site
595495000191	active site
595495000192	Zn2+ binding site [ion binding]; other site
595495000193	L-arabinose isomerase; Provisional; Region: PRK02929
595495000194	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
595495000195	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
595495000196	trimer interface [polypeptide binding]; other site
595495000197	putative substrate binding site [chemical binding]; other site
595495000198	putative metal binding site [ion binding]; other site
595495000199	ribulokinase; Provisional; Region: PRK04123
595495000200	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
595495000201	N- and C-terminal domain interface [polypeptide binding]; other site
595495000202	active site
595495000203	MgATP binding site [chemical binding]; other site
595495000204	catalytic site [active]
595495000205	metal binding site [ion binding]; metal-binding site
595495000206	carbohydrate binding site [chemical binding]; other site
595495000207	homodimer interface [polypeptide binding]; other site
595495000208	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
595495000209	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
595495000210	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495000211	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495000212	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
595495000213	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
595495000214	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
595495000215	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
595495000216	Walker A/P-loop; other site
595495000217	ATP binding site [chemical binding]; other site
595495000218	Q-loop/lid; other site
595495000219	ABC transporter signature motif; other site
595495000220	Walker B; other site
595495000221	D-loop; other site
595495000222	H-loop/switch region; other site
595495000223	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
595495000224	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495000225	dimer interface [polypeptide binding]; other site
595495000226	conserved gate region; other site
595495000227	putative PBP binding loops; other site
595495000228	ABC-ATPase subunit interface; other site
595495000229	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495000230	dimer interface [polypeptide binding]; other site
595495000231	conserved gate region; other site
595495000232	putative PBP binding loops; other site
595495000233	ABC-ATPase subunit interface; other site
595495000234	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
595495000235	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
595495000236	transcriptional regulator SgrR; Provisional; Region: PRK13626
595495000237	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
595495000238	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
595495000239	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495000240	sugar efflux transporter; Region: 2A0120; TIGR00899
595495000241	putative substrate translocation pore; other site
595495000242	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
595495000243	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
595495000244	substrate binding site [chemical binding]; other site
595495000245	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
595495000246	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
595495000247	substrate binding site [chemical binding]; other site
595495000248	ligand binding site [chemical binding]; other site
595495000249	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
595495000250	tartrate dehydrogenase; Region: TTC; TIGR02089
595495000251	2-isopropylmalate synthase; Validated; Region: PRK00915
595495000252	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
595495000253	active site
595495000254	catalytic residues [active]
595495000255	metal binding site [ion binding]; metal-binding site
595495000256	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
595495000257	leu operon leader peptide; Provisional; Region: PRK09925
595495000258	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
595495000259	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495000260	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
595495000261	putative substrate binding pocket [chemical binding]; other site
595495000262	putative dimerization interface [polypeptide binding]; other site
595495000263	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
595495000264	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
595495000265	PYR/PP interface [polypeptide binding]; other site
595495000266	dimer interface [polypeptide binding]; other site
595495000267	TPP binding site [chemical binding]; other site
595495000268	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495000269	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
595495000270	TPP-binding site [chemical binding]; other site
595495000271	dimer interface [polypeptide binding]; other site
595495000272	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
595495000273	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
595495000274	putative valine binding site [chemical binding]; other site
595495000275	dimer interface [polypeptide binding]; other site
595495000276	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
595495000277	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
595495000278	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
595495000279	DNA binding site [nucleotide binding]
595495000280	domain linker motif; other site
595495000281	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
595495000282	dimerization interface [polypeptide binding]; other site
595495000283	ligand binding site [chemical binding]; other site
595495000284	mraZ protein; Region: TIGR00242
595495000285	MraZ protein; Region: MraZ; pfam02381
595495000286	MraZ protein; Region: MraZ; pfam02381
595495000287	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
595495000288	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
595495000289	cell division protein FtsL; Provisional; Region: PRK10772
595495000290	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
595495000291	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
595495000292	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
595495000293	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
595495000294	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
595495000295	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
595495000296	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
595495000297	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
595495000298	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
595495000299	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
595495000300	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
595495000301	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
595495000302	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
595495000303	Mg++ binding site [ion binding]; other site
595495000304	putative catalytic motif [active]
595495000305	putative substrate binding site [chemical binding]; other site
595495000306	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
595495000307	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
595495000308	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
595495000309	cell division protein FtsW; Provisional; Region: PRK10774
595495000310	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
595495000311	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
595495000312	active site
595495000313	homodimer interface [polypeptide binding]; other site
595495000314	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
595495000315	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
595495000316	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
595495000317	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
595495000318	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
595495000319	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
595495000320	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
595495000321	cell division protein FtsQ; Provisional; Region: PRK10775
595495000322	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
595495000323	Cell division protein FtsQ; Region: FtsQ; pfam03799
595495000324	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
595495000325	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
595495000326	Cell division protein FtsA; Region: FtsA; pfam14450
595495000327	cell division protein FtsZ; Validated; Region: PRK09330
595495000328	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
595495000329	nucleotide binding site [chemical binding]; other site
595495000330	SulA interaction site; other site
595495000331	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
595495000332	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
595495000333	SecA regulator SecM; Provisional; Region: PRK02943
595495000334	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
595495000335	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
595495000336	SEC-C motif; Region: SEC-C; pfam02810
595495000337	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
595495000338	active site
595495000339	8-oxo-dGMP binding site [chemical binding]; other site
595495000340	nudix motif; other site
595495000341	metal binding site [ion binding]; metal-binding site
595495000342	DNA gyrase inhibitor; Reviewed; Region: PRK00418
595495000343	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
595495000344	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
595495000345	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
595495000346	CoA-binding site [chemical binding]; other site
595495000347	ATP-binding [chemical binding]; other site
595495000348	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
595495000349	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
595495000350	active site
595495000351	type IV pilin biogenesis protein; Provisional; Region: PRK10573
595495000352	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
595495000353	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
595495000354	hypothetical protein; Provisional; Region: PRK10436
595495000355	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
595495000356	Walker A motif; other site
595495000357	ATP binding site [chemical binding]; other site
595495000358	Walker B motif; other site
595495000359	putative major pilin subunit; Provisional; Region: PRK10574
595495000360	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
595495000361	Pilin (bacterial filament); Region: Pilin; pfam00114
595495000362	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
595495000363	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
595495000364	dimerization interface [polypeptide binding]; other site
595495000365	active site
595495000366	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
595495000367	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
595495000368	amidase catalytic site [active]
595495000369	Zn binding residues [ion binding]; other site
595495000370	substrate binding site [chemical binding]; other site
595495000371	regulatory protein AmpE; Provisional; Region: PRK10987
595495000372	aromatic amino acid transporter; Provisional; Region: PRK10238
595495000373	Transcriptional regulators [Transcription]; Region: FadR; COG2186
595495000374	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
595495000375	DNA-binding site [nucleotide binding]; DNA binding site
595495000376	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
595495000377	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
595495000378	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
595495000379	dimer interface [polypeptide binding]; other site
595495000380	TPP-binding site [chemical binding]; other site
595495000381	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
595495000382	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
595495000383	E3 interaction surface; other site
595495000384	lipoyl attachment site [posttranslational modification]; other site
595495000385	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
595495000386	E3 interaction surface; other site
595495000387	lipoyl attachment site [posttranslational modification]; other site
595495000388	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
595495000389	E3 interaction surface; other site
595495000390	lipoyl attachment site [posttranslational modification]; other site
595495000391	e3 binding domain; Region: E3_binding; pfam02817
595495000392	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
595495000393	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
595495000394	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
595495000395	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
595495000396	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
595495000397	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
595495000398	Protein of unknown function (DUF3106); Region: DUF3106; pfam11304
595495000399	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
595495000400	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
595495000401	substrate binding site [chemical binding]; other site
595495000402	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
595495000403	substrate binding site [chemical binding]; other site
595495000404	ligand binding site [chemical binding]; other site
595495000405	hypothetical protein; Provisional; Region: PRK05248
595495000406	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
595495000407	spermidine synthase; Provisional; Region: PRK00811
595495000408	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495000409	S-adenosylmethionine binding site [chemical binding]; other site
595495000410	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
595495000411	multicopper oxidase; Provisional; Region: PRK10965
595495000412	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
595495000413	Multicopper oxidase; Region: Cu-oxidase; pfam00394
595495000414	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
595495000415	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
595495000416	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
595495000417	Trp docking motif [polypeptide binding]; other site
595495000418	putative active site [active]
595495000419	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
595495000420	active site
595495000421	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
595495000422	active site clefts [active]
595495000423	zinc binding site [ion binding]; other site
595495000424	dimer interface [polypeptide binding]; other site
595495000425	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
595495000426	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
595495000427	Walker A/P-loop; other site
595495000428	ATP binding site [chemical binding]; other site
595495000429	Q-loop/lid; other site
595495000430	ABC transporter signature motif; other site
595495000431	Walker B; other site
595495000432	D-loop; other site
595495000433	H-loop/switch region; other site
595495000434	inner membrane transport permease; Provisional; Region: PRK15066
595495000435	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
595495000436	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
595495000437	active pocket/dimerization site; other site
595495000438	active site
595495000439	phosphorylation site [posttranslational modification]
595495000440	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
595495000441	putative active site [active]
595495000442	putative metal binding site [ion binding]; other site
595495000443	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
595495000444	tetramerization interface [polypeptide binding]; other site
595495000445	active site
595495000446	Uncharacterized conserved protein [Function unknown]; Region: COG5464
595495000447	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
595495000448	pantoate--beta-alanine ligase; Region: panC; TIGR00018
595495000449	Pantoate-beta-alanine ligase; Region: PanC; cd00560
595495000450	active site
595495000451	ATP-binding site [chemical binding]; other site
595495000452	pantoate-binding site; other site
595495000453	HXXH motif; other site
595495000454	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
595495000455	oligomerization interface [polypeptide binding]; other site
595495000456	active site
595495000457	metal binding site [ion binding]; metal-binding site
595495000458	putative fimbrial-like adhesin protein; Provisional; Region: PRK09723
595495000459	putative fimbrial protein StaF; Provisional; Region: PRK15262
595495000460	putative fimbrial protein StaE; Provisional; Region: PRK15263
595495000461	Fimbrial protein; Region: Fimbrial; cl01416
595495000462	putative fimbrial outer membrane usher protein; Provisional; Region: PRK09828
595495000463	PapC N-terminal domain; Region: PapC_N; pfam13954
595495000464	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
595495000465	PapC C-terminal domain; Region: PapC_C; pfam13953
595495000466	putative chaperone protein EcpD; Provisional; Region: PRK09926
595495000467	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
595495000468	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
595495000469	Fimbrial protein; Region: Fimbrial; cl01416
595495000470	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
595495000471	catalytic center binding site [active]
595495000472	ATP binding site [chemical binding]; other site
595495000473	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
595495000474	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
595495000475	active site
595495000476	NTP binding site [chemical binding]; other site
595495000477	metal binding triad [ion binding]; metal-binding site
595495000478	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
595495000479	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
595495000480	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
595495000481	tRNA synthetases class I (E and Q), catalytic domain; Region: tRNA-synt_1c; pfam00749
595495000482	active site
595495000483	nucleotide binding site [chemical binding]; other site
595495000484	HIGH motif; other site
595495000485	KMSKS motif; other site
595495000486	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
595495000487	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
595495000488	2'-5' RNA ligase; Provisional; Region: PRK15124
595495000489	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
595495000490	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
595495000491	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
595495000492	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
595495000493	ATP binding site [chemical binding]; other site
595495000494	putative Mg++ binding site [ion binding]; other site
595495000495	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
595495000496	nucleotide binding region [chemical binding]; other site
595495000497	ATP-binding site [chemical binding]; other site
595495000498	Helicase associated domain (HA2) Add an annotation; Region: HA2; smart00847
595495000499	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
595495000500	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
595495000501	Transglycosylase; Region: Transgly; pfam00912
595495000502	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
595495000503	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
595495000504	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
595495000505	N-terminal plug; other site
595495000506	ligand-binding site [chemical binding]; other site
595495000507	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
595495000508	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
595495000509	Walker A/P-loop; other site
595495000510	ATP binding site [chemical binding]; other site
595495000511	Q-loop/lid; other site
595495000512	ABC transporter signature motif; other site
595495000513	Walker B; other site
595495000514	D-loop; other site
595495000515	H-loop/switch region; other site
595495000516	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
595495000517	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
595495000518	siderophore binding site; other site
595495000519	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
595495000520	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
595495000521	ABC-ATPase subunit  interface; other site
595495000522	dimer interface [polypeptide binding]; other site
595495000523	putative PBP binding regions; other site
595495000524	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
595495000525	ABC-ATPase subunit  interface; other site
595495000526	dimer interface [polypeptide binding]; other site
595495000527	putative PBP binding regions; other site
595495000528	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
595495000529	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
595495000530	inhibitor-cofactor binding pocket; inhibition site
595495000531	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495000532	catalytic residue [active]
595495000533	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
595495000534	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
595495000535	Cl- selectivity filter; other site
595495000536	Cl- binding residues [ion binding]; other site
595495000537	pore gating glutamate residue; other site
595495000538	dimer interface [polypeptide binding]; other site
595495000539	H+/Cl- coupling transport residue; other site
595495000540	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
595495000541	hypothetical protein; Provisional; Region: PRK10578
595495000542	UPF0126 domain; Region: UPF0126; pfam03458
595495000543	UPF0126 domain; Region: UPF0126; pfam03458
595495000544	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
595495000545	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
595495000546	cobalamin binding residues [chemical binding]; other site
595495000547	putative BtuC binding residues; other site
595495000548	dimer interface [polypeptide binding]; other site
595495000549	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
595495000550	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
595495000551	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
595495000552	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
595495000553	Zn2+ binding site [ion binding]; other site
595495000554	Mg2+ binding site [ion binding]; other site
595495000555	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
595495000556	serine endoprotease; Provisional; Region: PRK10942
595495000557	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
595495000558	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
595495000559	protein binding site [polypeptide binding]; other site
595495000560	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
595495000561	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
595495000562	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
595495000563	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
595495000564	hypothetical protein; Provisional; Region: PRK13677
595495000565	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
595495000566	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
595495000567	trimer interface [polypeptide binding]; other site
595495000568	active site
595495000569	substrate binding site [chemical binding]; other site
595495000570	CoA binding site [chemical binding]; other site
595495000571	PII uridylyl-transferase; Provisional; Region: PRK05007
595495000572	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
595495000573	metal binding triad; other site
595495000574	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
595495000575	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
595495000576	Zn2+ binding site [ion binding]; other site
595495000577	Mg2+ binding site [ion binding]; other site
595495000578	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
595495000579	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
595495000580	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
595495000581	active site
595495000582	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
595495000583	rRNA interaction site [nucleotide binding]; other site
595495000584	S8 interaction site; other site
595495000585	putative laminin-1 binding site; other site
595495000586	elongation factor Ts; Provisional; Region: tsf; PRK09377
595495000587	UBA/TS-N domain; Region: UBA; pfam00627
595495000588	Elongation factor TS; Region: EF_TS; pfam00889
595495000589	Elongation factor TS; Region: EF_TS; pfam00889
595495000590	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
595495000591	putative nucleotide binding site [chemical binding]; other site
595495000592	uridine monophosphate binding site [chemical binding]; other site
595495000593	homohexameric interface [polypeptide binding]; other site
595495000594	ribosome recycling factor; Reviewed; Region: frr; PRK00083
595495000595	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
595495000596	hinge region; other site
595495000597	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
595495000598	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
595495000599	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
595495000600	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
595495000601	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
595495000602	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
595495000603	catalytic residue [active]
595495000604	putative FPP diphosphate  binding site; other site
595495000605	putative FPP binding hydrophobic cleft; other site
595495000606	dimer interface [polypeptide binding]; other site
595495000607	putative IPP diphosphate binding site; other site
595495000608	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
595495000609	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
595495000610	zinc metallopeptidase RseP; Provisional; Region: PRK10779
595495000611	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
595495000612	active site
595495000613	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
595495000614	protein binding site [polypeptide binding]; other site
595495000615	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
595495000616	putative substrate binding region [chemical binding]; other site
595495000617	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
595495000618	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
595495000619	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
595495000620	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
595495000621	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
595495000622	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
595495000623	Surface antigen; Region: Bac_surface_Ag; pfam01103
595495000624	periplasmic chaperone; Provisional; Region: PRK10780
595495000625	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
595495000626	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
595495000627	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
595495000628	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
595495000629	trimer interface [polypeptide binding]; other site
595495000630	active site
595495000631	UDP-GlcNAc binding site [chemical binding]; other site
595495000632	lipid binding site [chemical binding]; lipid-binding site
595495000633	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
595495000634	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
595495000635	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
595495000636	active site
595495000637	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
595495000638	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
595495000639	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
595495000640	RNA/DNA hybrid binding site [nucleotide binding]; other site
595495000641	active site
595495000642	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
595495000643	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
595495000644	putative active site [active]
595495000645	putative PHP Thumb interface [polypeptide binding]; other site
595495000646	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
595495000647	generic binding surface II; other site
595495000648	generic binding surface I; other site
595495000649	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
595495000650	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
595495000651	lysine decarboxylase LdcC; Provisional; Region: PRK15399
595495000652	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
595495000653	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
595495000654	homodimer interface [polypeptide binding]; other site
595495000655	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495000656	catalytic residue [active]
595495000657	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
595495000658	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
595495000659	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
595495000660	putative metal binding site [ion binding]; other site
595495000661	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
595495000662	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
595495000663	Ligand Binding Site [chemical binding]; other site
595495000664	TilS substrate binding domain; Region: TilS; pfam09179
595495000665	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
595495000666	Rho-binding antiterminator; Provisional; Region: PRK11625
595495000667	hypothetical protein; Provisional; Region: PRK04964
595495000668	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
595495000669	hypothetical protein; Provisional; Region: PRK09256
595495000670	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
595495000671	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
595495000672	NlpE N-terminal domain; Region: NlpE; pfam04170
595495000673	hypothetical protein; Provisional; Region: PRK11479
595495000674	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
595495000675	prolyl-tRNA synthetase; Provisional; Region: PRK09194
595495000676	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
595495000677	dimer interface [polypeptide binding]; other site
595495000678	motif 1; other site
595495000679	active site
595495000680	motif 2; other site
595495000681	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
595495000682	putative deacylase active site [active]
595495000683	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
595495000684	active site
595495000685	motif 3; other site
595495000686	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
595495000687	anticodon binding site; other site
595495000688	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
595495000689	homodimer interaction site [polypeptide binding]; other site
595495000690	cofactor binding site; other site
595495000691	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
595495000692	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
595495000693	lipoprotein, YaeC family; Region: TIGR00363
595495000694	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495000695	dimer interface [polypeptide binding]; other site
595495000696	conserved gate region; other site
595495000697	ABC-ATPase subunit interface; other site
595495000698	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
595495000699	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
595495000700	Walker A/P-loop; other site
595495000701	ATP binding site [chemical binding]; other site
595495000702	Q-loop/lid; other site
595495000703	ABC transporter signature motif; other site
595495000704	Walker B; other site
595495000705	D-loop; other site
595495000706	H-loop/switch region; other site
595495000707	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
595495000708	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
595495000709	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495000710	active site
595495000711	motif I; other site
595495000712	motif II; other site
595495000713	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
595495000714	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
595495000715	active site
595495000716	catalytic tetrad [active]
595495000717	Transcriptional regulator [Transcription]; Region: LysR; COG0583
595495000718	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495000719	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
595495000720	putative effector binding pocket; other site
595495000721	dimerization interface [polypeptide binding]; other site
595495000722	hypothetical protein; Provisional; Region: PRK05421
595495000723	putative catalytic site [active]
595495000724	putative metal binding site [ion binding]; other site
595495000725	putative phosphate binding site [ion binding]; other site
595495000726	putative catalytic site [active]
595495000727	putative phosphate binding site [ion binding]; other site
595495000728	putative metal binding site [ion binding]; other site
595495000729	Methyltransferase domain; Region: Methyltransf_31; pfam13847
595495000730	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495000731	S-adenosylmethionine binding site [chemical binding]; other site
595495000732	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
595495000733	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
595495000734	N-acetyl-D-glucosamine binding site [chemical binding]; other site
595495000735	catalytic residue [active]
595495000736	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
595495000737	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
595495000738	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
595495000739	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
595495000740	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
595495000741	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495000742	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
595495000743	RNA/DNA hybrid binding site [nucleotide binding]; other site
595495000744	active site
595495000745	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
595495000746	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
595495000747	active site
595495000748	catalytic site [active]
595495000749	substrate binding site [chemical binding]; other site
595495000750	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
595495000751	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
595495000752	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
595495000753	ImpA domain protein; Region: DUF3702; pfam12486
595495000754	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
595495000755	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
595495000756	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
595495000757	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
595495000758	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
595495000759	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
595495000760	type VI secretion-associated protein, VC_A0118 family; Region: VI_minor_1; TIGR03360
595495000761	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
595495000762	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495000763	Walker A motif; other site
595495000764	ATP binding site [chemical binding]; other site
595495000765	Walker B motif; other site
595495000766	arginine finger; other site
595495000767	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495000768	Walker A motif; other site
595495000769	ATP binding site [chemical binding]; other site
595495000770	Walker B motif; other site
595495000771	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
595495000772	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
595495000773	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
595495000774	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
595495000775	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3521
595495000776	Predicted component of the type VI protein secretion system, contains a FHA domain [Intracellular trafficking, secretion, and vesicular    transport; Signal transduction mechanisms]; Region: COG3456
595495000777	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
595495000778	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
595495000779	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
595495000780	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
595495000781	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
595495000782	Protein of unknown function (DUF877); Region: DUF877; pfam05943
595495000783	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
595495000784	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3516
595495000785	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
595495000786	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
595495000787	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
595495000788	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
595495000789	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
595495000790	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
595495000791	RHS Repeat; Region: RHS_repeat; pfam05593
595495000792	RHS Repeat; Region: RHS_repeat; pfam05593
595495000793	RHS Repeat; Region: RHS_repeat; pfam05593
595495000794	RHS Repeat; Region: RHS_repeat; pfam05593
595495000795	RHS Repeat; Region: RHS_repeat; cl11982
595495000796	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
595495000797	RHS Repeat; Region: RHS_repeat; pfam05593
595495000798	RHS Repeat; Region: RHS_repeat; pfam05593
595495000799	RHS protein; Region: RHS; pfam03527
595495000800	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
595495000801	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
595495000802	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
595495000803	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495000804	Transposase [DNA replication, recombination, and repair]; Region: COG5433
595495000805	Transposase [DNA replication, recombination, and repair]; Region: COG5433
595495000806	C-N hydrolase family amidase; Provisional; Region: PRK10438
595495000807	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
595495000808	putative active site [active]
595495000809	catalytic triad [active]
595495000810	dimer interface [polypeptide binding]; other site
595495000811	multimer interface [polypeptide binding]; other site
595495000812	C-lysozyme inhibitor; Provisional; Region: PRK09993
595495000813	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
595495000814	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
595495000815	active site
595495000816	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
595495000817	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
595495000818	dimer interface [polypeptide binding]; other site
595495000819	active site
595495000820	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
595495000821	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
595495000822	putative active site [active]
595495000823	putative dimer interface [polypeptide binding]; other site
595495000824	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
595495000825	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
595495000826	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
595495000827	RelB antitoxin; Region: RelB; cl01171
595495000828	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
595495000829	NlpC/P60 family; Region: NLPC_P60; pfam00877
595495000830	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
595495000831	HicB family; Region: HicB; pfam05534
595495000832	Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; COG1298
595495000833	FHIPEP family; Region: FHIPEP; pfam00771
595495000834	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
595495000835	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
595495000836	Flagellar biosynthesis pathway, component FliR [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliR; COG1684
595495000837	Bacterial export proteins, family 3; Region: Bac_export_3; cl00867
595495000838	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
595495000839	flagellar motor switch protein FliN; Region: fliN; TIGR02480
595495000840	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
595495000841	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
595495000842	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495000843	Walker A motif; other site
595495000844	ATP binding site [chemical binding]; other site
595495000845	Walker B motif; other site
595495000846	arginine finger; other site
595495000847	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
595495000848	Flagellar hook-basal body complex protein FliE; Region: FliE; pfam02049
595495000849	flagellar MS-ring protein; Reviewed; Region: fliF; PRK07193
595495000850	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
595495000851	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
595495000852	flagellar motor switch protein G; Reviewed; Region: fliG; PRK07194
595495000853	MgtE intracellular N domain; Region: MgtE_N; smart00924
595495000854	FliG C-terminal domain; Region: FliG_C; pfam01706
595495000855	flagellar assembly protein H; Provisional; Region: fliH; PRK13386
595495000856	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
595495000857	Flagellar assembly protein FliH; Region: FliH; pfam02108
595495000858	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07196
595495000859	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
595495000860	Walker A motif/ATP binding site; other site
595495000861	Walker B motif; other site
595495000862	flagellar export protein FliJ; Region: flagell_FliJ; TIGR02473
595495000863	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
595495000864	active site
595495000865	nucleotide binding site [chemical binding]; other site
595495000866	HIGH motif; other site
595495000867	KMSKS motif; other site
595495000868	Mu-like prophage protein Com; Region: Mu-like_Com; cl11540
595495000869	multiple promoter invertase; Provisional; Region: mpi; PRK13413
595495000870	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
595495000871	catalytic residues [active]
595495000872	catalytic nucleophile [active]
595495000873	Presynaptic Site I dimer interface [polypeptide binding]; other site
595495000874	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
595495000875	Synaptic Flat tetramer interface [polypeptide binding]; other site
595495000876	Synaptic Site I dimer interface [polypeptide binding]; other site
595495000877	DNA binding site [nucleotide binding]
595495000878	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
595495000879	DNA-binding interface [nucleotide binding]; DNA binding site
595495000880	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
595495000881	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
595495000882	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
595495000883	Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; cl01542
595495000884	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
595495000885	Phage protein GP46; Region: GP46; pfam07409
595495000886	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
595495000887	Bacteriophage Mu Gp45 protein; Region: Phage_Mu_Gp45; pfam06890
595495000888	Mu-like prophage tail protein gpP [General function prediction only]; Region: COG4379
595495000889	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
595495000890	Mu-like prophage DNA circulation protein [General function prediction only]; Region: COG4228
595495000891	DNA circulation protein N-terminus; Region: DNA_circ_N; pfam07157
595495000892	Mu-like prophage protein [General function prediction only]; Region: COG3941
595495000893	tape measure domain; Region: tape_meas_nterm; TIGR02675
595495000894	Mu-like prophage FluMu protein gp41 [Function unknown]; Region: COG4518
595495000895	Phage tail tube protein; Region: Tail_tube; pfam10618
595495000896	Mu-like prophage tail sheath protein gpL [General function prediction only]; Region: COG4386
595495000897	Phage tail sheath protein; Region: Phage_sheath_1; pfam04984
595495000898	Protein of unknown function (DUF2635); Region: DUF2635; pfam10948
595495000899	Domain of unknown function (DUF1834); Region: DUF1834; pfam08873
595495000900	Protein of unknown function (DUF1320); Region: DUF1320; pfam07030
595495000901	Mu-like prophage major head subunit gpT; Region: Mu-like_gpT; pfam10124
595495000902	Mu-like prophage I protein; Region: Mu-like_Pro; pfam10123
595495000903	phage virion morphogenesis (putative tail completion) protein; Region: tail_comp_S; TIGR01635
595495000904	Uncharacterized protein, homolog of phage Mu protein gp30 [Function unknown]; Region: COG2369
595495000905	Phage Mu protein F like protein; Region: Phage_Mu_F; pfam04233
595495000906	Protein of unknown function (DUF935); Region: DUF935; pfam06074
595495000907	Mu-like prophage protein gp29 [Function unknown]; Region: COG4383
595495000908	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
595495000909	Protein of unknown function (DUF3486); Region: DUF3486; pfam11985
595495000910	Protein of unknown function (DUF2730); Region: DUF2730; pfam10805
595495000911	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
595495000912	catalytic residues [active]
595495000913	Mor transcription activator family; Region: Mor; pfam08765
595495000914	Mor transcription activator family; Region: Mor; pfam08765
595495000915	Protein of unknown function (DUF1018); Region: DUF1018; pfam06252
595495000916	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
595495000917	Bacteriophage Mu Gam like protein; Region: Phage_Mu_Gam; cl01825
595495000918	Uncharacterized ATPase, putative transposase [General function prediction only]; Region: COG2842
595495000919	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
595495000920	Walker A motif; other site
595495000921	ATP binding site [chemical binding]; other site
595495000922	Walker B motif; other site
595495000923	Mu B transposition protein, C terminal; Region: Phage-MuB_C; pfam09077
595495000924	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
595495000925	Mu DNA binding, I gamma subdomain; Region: HTH_Tnp_Mu_2; pfam09039
595495000926	Bacteriophage Mu transposase; Region: DDE_2; pfam02914
595495000927	Mu transposase, C-terminal; Region: Mu-transpos_C; pfam09299
595495000928	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
595495000929	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
595495000930	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
595495000931	L-aspartate oxidase; Provisional; Region: PRK06175
595495000932	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
595495000933	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
595495000934	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
595495000935	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
595495000936	D-subunit interface [polypeptide binding]; other site
595495000937	Iron-sulfur protein interface; other site
595495000938	proximal quinone binding site [chemical binding]; other site
595495000939	distal quinone binding site [chemical binding]; other site
595495000940	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
595495000941	Iron-sulfur protein interface; other site
595495000942	proximal quinone binding site [chemical binding]; other site
595495000943	C-subunit interface; other site
595495000944	distal quinone binding site; other site
595495000945	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
595495000946	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
595495000947	Bacterial lipocalin [Cell envelope biogenesis, outer membrane]; Region: Blc; COG3040
595495000948	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
595495000949	multidrug efflux system protein; Provisional; Region: PRK11431
595495000950	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
595495000951	entericidin A; Provisional; Region: PRK09810
595495000952	elongation factor P; Validated; Region: PRK00529
595495000953	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
595495000954	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
595495000955	RNA binding site [nucleotide binding]; other site
595495000956	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
595495000957	RNA binding site [nucleotide binding]; other site
595495000958	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
595495000959	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495000960	FeS/SAM binding site; other site
595495000961	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
595495000962	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
595495000963	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
595495000964	ring oligomerisation interface [polypeptide binding]; other site
595495000965	ATP/Mg binding site [chemical binding]; other site
595495000966	stacking interactions; other site
595495000967	hinge regions; other site
595495000968	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
595495000969	oligomerisation interface [polypeptide binding]; other site
595495000970	mobile loop; other site
595495000971	roof hairpin; other site
595495000972	putative transporter; Provisional; Region: PRK11021
595495000973	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
595495000974	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
595495000975	Aspartase; Region: Aspartase; cd01357
595495000976	active sites [active]
595495000977	tetramer interface [polypeptide binding]; other site
595495000978	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
595495000979	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
595495000980	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
595495000981	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
595495000982	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
595495000983	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
595495000984	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
595495000985	DsbD alpha interface [polypeptide binding]; other site
595495000986	catalytic residues [active]
595495000987	putative transcriptional regulator; Provisional; Region: PRK11640
595495000988	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
595495000989	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
595495000990	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
595495000991	DNA binding site [nucleotide binding]
595495000992	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
595495000993	lysine decarboxylase CadA; Provisional; Region: PRK15400
595495000994	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
595495000995	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
595495000996	homodimer interface [polypeptide binding]; other site
595495000997	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495000998	catalytic residue [active]
595495000999	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
595495001000	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
595495001001	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495001002	putative substrate translocation pore; other site
595495001003	POT family; Region: PTR2; pfam00854
595495001004	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
595495001005	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
595495001006	dimer interface [polypeptide binding]; other site
595495001007	putative anticodon binding site; other site
595495001008	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
595495001009	motif 1; other site
595495001010	active site
595495001011	motif 2; other site
595495001012	motif 3; other site
595495001013	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
595495001014	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
595495001015	Predicted acetyltransferase [General function prediction only]; Region: COG2388
595495001016	Uncharacterized conserved protein [Function unknown]; Region: COG3592
595495001017	sensory histidine kinase DcuS; Provisional; Region: PRK11086
595495001018	PAS domain; Region: PAS; smart00091
595495001019	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495001020	ATP binding site [chemical binding]; other site
595495001021	Mg2+ binding site [ion binding]; other site
595495001022	G-X-G motif; other site
595495001023	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
595495001024	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495001025	active site
595495001026	phosphorylation site [posttranslational modification]
595495001027	intermolecular recognition site; other site
595495001028	dimerization interface [polypeptide binding]; other site
595495001029	Transcriptional regulator; Region: CitT; pfam12431
595495001030	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
595495001031	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
595495001032	fumarate hydratase; Provisional; Region: PRK15389
595495001033	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
595495001034	Fumarase C-terminus; Region: Fumerase_C; pfam05683
595495001035	hypothetical protein; Provisional; Region: PRK09867
595495001036	melibiose:sodium symporter; Provisional; Region: PRK10429
595495001037	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
595495001038	alpha-galactosidase; Provisional; Region: PRK15076
595495001039	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
595495001040	NAD binding site [chemical binding]; other site
595495001041	sugar binding site [chemical binding]; other site
595495001042	divalent metal binding site [ion binding]; other site
595495001043	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
595495001044	dimer interface [polypeptide binding]; other site
595495001045	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
595495001046	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495001047	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495001048	arginine decarboxylase; Provisional; Region: PRK15029
595495001049	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
595495001050	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
595495001051	homodimer interface [polypeptide binding]; other site
595495001052	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495001053	catalytic residue [active]
595495001054	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
595495001055	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
595495001056	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495001057	arginine:agmatin antiporter; Provisional; Region: PRK10644
595495001058	putative metal dependent hydrolase; Provisional; Region: PRK11598
595495001059	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
595495001060	Sulfatase; Region: Sulfatase; pfam00884
595495001061	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
595495001062	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495001063	active site
595495001064	phosphorylation site [posttranslational modification]
595495001065	intermolecular recognition site; other site
595495001066	dimerization interface [polypeptide binding]; other site
595495001067	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
595495001068	DNA binding site [nucleotide binding]
595495001069	sensor protein BasS/PmrB; Provisional; Region: PRK10755
595495001070	HAMP domain; Region: HAMP; pfam00672
595495001071	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
595495001072	dimer interface [polypeptide binding]; other site
595495001073	phosphorylation site [posttranslational modification]
595495001074	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495001075	ATP binding site [chemical binding]; other site
595495001076	Mg2+ binding site [ion binding]; other site
595495001077	G-X-G motif; other site
595495001078	proline/glycine betaine transporter; Provisional; Region: PRK10642
595495001079	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495001080	putative substrate translocation pore; other site
595495001081	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
595495001082	YjcZ-like protein; Region: YjcZ; pfam13990
595495001083	hypothetical protein; Provisional; Region: PRK09866
595495001084	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
595495001085	G1 box; other site
595495001086	GTP/Mg2+ binding site [chemical binding]; other site
595495001087	G2 box; other site
595495001088	Switch I region; other site
595495001089	G3 box; other site
595495001090	Switch II region; other site
595495001091	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
595495001092	G2 box; other site
595495001093	Switch I region; other site
595495001094	G3 box; other site
595495001095	Switch II region; other site
595495001096	G4 box; other site
595495001097	G5 box; other site
595495001098	hypothetical protein; Provisional; Region: PRK10220
595495001099	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
595495001100	PhnA protein; Region: PhnA; pfam03831
595495001101	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
595495001102	dimer interface [polypeptide binding]; other site
595495001103	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
595495001104	phosphonate/organophosphate ester transporter subunit; Provisional; Region: PRK09984
595495001105	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
595495001106	Walker A/P-loop; other site
595495001107	ATP binding site [chemical binding]; other site
595495001108	Q-loop/lid; other site
595495001109	ABC transporter signature motif; other site
595495001110	Walker B; other site
595495001111	D-loop; other site
595495001112	H-loop/switch region; other site
595495001113	phosphonate ABC transporter, periplasmic phosphonate binding protein; Region: PhnD; TIGR03431
595495001114	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
595495001115	substrate binding pocket [chemical binding]; other site
595495001116	membrane-bound complex binding site; other site
595495001117	hinge residues; other site
595495001118	ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism]; Region: COG3639
595495001119	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495001120	conserved gate region; other site
595495001121	phosphonate metabolism transcriptional regulator PhnF; Provisional; Region: PRK10079
595495001122	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
595495001123	DNA-binding site [nucleotide binding]; DNA binding site
595495001124	UTRA domain; Region: UTRA; pfam07702
595495001125	Phosphonate metabolism protein PhnG; Region: PhnG; pfam06754
595495001126	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnH; COG3625
595495001127	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnI; COG3626
595495001128	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnJ; COG3627
595495001129	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
595495001130	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
595495001131	Walker A/P-loop; other site
595495001132	ATP binding site [chemical binding]; other site
595495001133	Q-loop/lid; other site
595495001134	ABC transporter signature motif; other site
595495001135	Walker B; other site
595495001136	D-loop; other site
595495001137	H-loop/switch region; other site
595495001138	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
595495001139	ABC-type phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PhnL; COG4778
595495001140	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
595495001141	Walker A/P-loop; other site
595495001142	ATP binding site [chemical binding]; other site
595495001143	Q-loop/lid; other site
595495001144	ABC transporter signature motif; other site
595495001145	Walker B; other site
595495001146	D-loop; other site
595495001147	H-loop/switch region; other site
595495001148	phosphonate metabolism protein PhnM; Provisional; Region: PRK15446
595495001149	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
595495001150	PhnM is believed to be a subunit of the membrane associated C-P lyase complex. C-P lyase is thought to catalyze the direct cleavage of inactivated C-P bonds to yield inorganic phosphate and the corresponding hydrocarbons. It is responsible for cleavage...; Region: PhnM; cd01306
595495001151	active site
595495001152	ribose 1,5-bisphosphokinase; Provisional; Region: PRK10078
595495001153	AAA domain; Region: AAA_18; pfam13238
595495001154	active site
595495001155	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
595495001156	Coenzyme A binding pocket [chemical binding]; other site
595495001157	carbon-phosphorus lyase complex accessory protein; Provisional; Region: phnP; PRK11244
595495001158	ribose 5-phosphate isomerase B; Region: rpiB; TIGR01120
595495001159	DNA-binding transcriptional repressor RpiR; Provisional; Region: PRK11337
595495001160	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
595495001161	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
595495001162	putative active site [active]
595495001163	D-allose transporter subunit; Provisional; Region: PRK09701
595495001164	Periplasmic allose-binding domain of bacterial transport systems that function as a primary receptor of active transport and chemotaxis; Region: PBP1_allose_binding; cd06320
595495001165	ligand binding site [chemical binding]; other site
595495001166	dimerization interface [polypeptide binding]; other site
595495001167	zinc binding site [ion binding]; other site
595495001168	D-allose transporter ATP-binding protein; Provisional; Region: PRK09700
595495001169	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495001170	Walker A/P-loop; other site
595495001171	ATP binding site [chemical binding]; other site
595495001172	Q-loop/lid; other site
595495001173	ABC transporter signature motif; other site
595495001174	Walker B; other site
595495001175	D-loop; other site
595495001176	H-loop/switch region; other site
595495001177	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
595495001178	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
595495001179	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
595495001180	TM-ABC transporter signature motif; other site
595495001181	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
595495001182	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
595495001183	substrate binding site [chemical binding]; other site
595495001184	hexamer interface [polypeptide binding]; other site
595495001185	metal binding site [ion binding]; metal-binding site
595495001186	D-allose kinase; Provisional; Region: PRK09698
595495001187	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
595495001188	nucleotide binding site [chemical binding]; other site
595495001189	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
595495001190	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495001191	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
595495001192	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
595495001193	multidrug resistance protein MdtN; Provisional; Region: PRK10476
595495001194	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
595495001195	HlyD family secretion protein; Region: HlyD_3; pfam13437
595495001196	multidrug efflux system protein MdtO; Provisional; Region: PRK11427
595495001197	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
595495001198	putative outer membrane efflux protein MdtP; Provisional; Region: PRK09915
595495001199	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
595495001200	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
595495001201	[4Fe-4S] binding site [ion binding]; other site
595495001202	molybdopterin cofactor binding site; other site
595495001203	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
595495001204	molybdopterin cofactor binding site; other site
595495001205	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
595495001206	Sel1-like repeats; Region: SEL1; smart00671
595495001207	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
595495001208	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
595495001209	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
595495001210	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
595495001211	binding surface
595495001212	TPR motif; other site
595495001213	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
595495001214	heme lyase subunit NrfE; Provisional; Region: PRK10369
595495001215	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
595495001216	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
595495001217	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
595495001218	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
595495001219	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
595495001220	acetyl-CoA synthetase; Provisional; Region: PRK00174
595495001221	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
595495001222	active site
595495001223	CoA binding site [chemical binding]; other site
595495001224	acyl-activating enzyme (AAE) consensus motif; other site
595495001225	AMP binding site [chemical binding]; other site
595495001226	acetate binding site [chemical binding]; other site
595495001227	Predicted membrane protein [Function unknown]; Region: COG3162
595495001228	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
595495001229	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
595495001230	Na binding site [ion binding]; other site
595495001231	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
595495001232	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
595495001233	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
595495001234	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
595495001235	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
595495001236	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
595495001237	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
595495001238	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
595495001239	DNA binding residues [nucleotide binding]
595495001240	dimer interface [polypeptide binding]; other site
595495001241	[2Fe-2S] cluster binding site [ion binding]; other site
595495001242	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
595495001243	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495001244	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
595495001245	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
595495001246	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
595495001247	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
595495001248	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
595495001249	dimer interface [polypeptide binding]; other site
595495001250	ssDNA binding site [nucleotide binding]; other site
595495001251	tetramer (dimer of dimers) interface [polypeptide binding]; other site
595495001252	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
595495001253	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
595495001254	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
595495001255	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
595495001256	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
595495001257	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
595495001258	Uncharacterized protein family UPF0047; Region: UPF0047; cl00439
595495001259	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495001260	active site
595495001261	motif I; other site
595495001262	motif II; other site
595495001263	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
595495001264	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
595495001265	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495001266	homodimer interface [polypeptide binding]; other site
595495001267	catalytic residue [active]
595495001268	alanine racemase; Reviewed; Region: alr; PRK00053
595495001269	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
595495001270	active site
595495001271	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
595495001272	substrate binding site [chemical binding]; other site
595495001273	catalytic residues [active]
595495001274	dimer interface [polypeptide binding]; other site
595495001275	replicative DNA helicase; Provisional; Region: PRK08006
595495001276	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
595495001277	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
595495001278	Walker A motif; other site
595495001279	ATP binding site [chemical binding]; other site
595495001280	Walker B motif; other site
595495001281	DNA binding loops [nucleotide binding]
595495001282	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
595495001283	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
595495001284	NADP binding site [chemical binding]; other site
595495001285	dimer interface [polypeptide binding]; other site
595495001286	phage shock protein G; Reviewed; Region: pspG; PRK09459
595495001287	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
595495001288	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
595495001289	FMN binding site [chemical binding]; other site
595495001290	active site
595495001291	catalytic residues [active]
595495001292	substrate binding site [chemical binding]; other site
595495001293	Protein of unknown function (DUF2713); Region: DUF2713; pfam10897
595495001294	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
595495001295	metal binding site 2 [ion binding]; metal-binding site
595495001296	putative DNA binding helix; other site
595495001297	metal binding site 1 [ion binding]; metal-binding site
595495001298	dimer interface [polypeptide binding]; other site
595495001299	structural Zn2+ binding site [ion binding]; other site
595495001300	hypothetical protein; Provisional; Region: PRK10428
595495001301	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
595495001302	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
595495001303	LexA repressor; Validated; Region: PRK00215
595495001304	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
595495001305	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
595495001306	Catalytic site [active]
595495001307	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
595495001308	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
595495001309	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
595495001310	putative acyl-acceptor binding pocket; other site
595495001311	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
595495001312	UbiA prenyltransferase family; Region: UbiA; pfam01040
595495001313	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
595495001314	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
595495001315	SopA-like central domain; Region: SopA; pfam13981
595495001316	hypothetical protein; Validated; Region: PRK09718
595495001317	maltose regulon periplasmic protein; Provisional; Region: PRK10564
595495001318	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
595495001319	trimer interface; other site
595495001320	sugar binding site [chemical binding]; other site
595495001321	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
595495001322	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
595495001323	Walker A/P-loop; other site
595495001324	ATP binding site [chemical binding]; other site
595495001325	Q-loop/lid; other site
595495001326	ABC transporter signature motif; other site
595495001327	Walker B; other site
595495001328	D-loop; other site
595495001329	H-loop/switch region; other site
595495001330	TOBE domain; Region: TOBE_2; pfam08402
595495001331	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
595495001332	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
595495001333	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
595495001334	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495001335	dimer interface [polypeptide binding]; other site
595495001336	conserved gate region; other site
595495001337	putative PBP binding loops; other site
595495001338	ABC-ATPase subunit interface; other site
595495001339	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
595495001340	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495001341	dimer interface [polypeptide binding]; other site
595495001342	conserved gate region; other site
595495001343	putative PBP binding loops; other site
595495001344	ABC-ATPase subunit interface; other site
595495001345	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
595495001346	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495001347	putative substrate translocation pore; other site
595495001348	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495001349	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
595495001350	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
595495001351	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
595495001352	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
595495001353	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
595495001354	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
595495001355	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
595495001356	active site
595495001357	dimer interface [polypeptide binding]; other site
595495001358	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
595495001359	dimer interface [polypeptide binding]; other site
595495001360	active site
595495001361	aspartate kinase III; Validated; Region: PRK09084
595495001362	AAK_AKiii-LysC-EC: Amino Acid Kinase Superfamily (AAK), AKiii-LysC-EC: this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKIII. AKIII is a monofunctional class enzyme (LysC) found in some...; Region: AAK_AKiii-LysC-EC; cd04258
595495001363	nucleotide binding site [chemical binding]; other site
595495001364	putative catalytic residues [active]
595495001365	aspartate binding site [chemical binding]; other site
595495001366	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_1; cd04932
595495001367	lysine allosteric regulatory site; other site
595495001368	dimer interface [polypeptide binding]; other site
595495001369	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
595495001370	dimer interface [polypeptide binding]; other site
595495001371	Zeta toxin; Region: Zeta_toxin; pfam06414
595495001372	Predicted nucleotidyltransferase; Region: Nuc-transf; pfam10127
595495001373	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
595495001374	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
595495001375	hypothetical protein; Provisional; Region: PRK10515
595495001376	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
595495001377	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
595495001378	RNA binding surface [nucleotide binding]; other site
595495001379	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
595495001380	probable active site [active]
595495001381	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
595495001382	active site pocket [active]
595495001383	oxyanion hole [active]
595495001384	catalytic triad [active]
595495001385	active site nucleophile [active]
595495001386	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
595495001387	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
595495001388	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
595495001389	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
595495001390	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
595495001391	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
595495001392	substrate binding pocket [chemical binding]; other site
595495001393	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
595495001394	B12 binding site [chemical binding]; other site
595495001395	cobalt ligand [ion binding]; other site
595495001396	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
595495001397	transcriptional repressor IclR; Provisional; Region: PRK11569
595495001398	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
595495001399	Bacterial transcriptional regulator; Region: IclR; pfam01614
595495001400	ShET2 enterotoxin, N-terminal region; Region: Toxin_15; pfam07906
595495001401	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
595495001402	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
595495001403	isocitrate lyase; Provisional; Region: PRK15063
595495001404	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
595495001405	tetramer interface [polypeptide binding]; other site
595495001406	active site
595495001407	Mg2+/Mn2+ binding site [ion binding]; other site
595495001408	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
595495001409	malate synthase A; Region: malate_syn_A; TIGR01344
595495001410	active site
595495001411	homoserine O-succinyltransferase; Provisional; Region: PRK05368
595495001412	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
595495001413	proposed active site lysine [active]
595495001414	conserved cys residue [active]
595495001415	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
595495001416	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
595495001417	Coenzyme A binding pocket [chemical binding]; other site
595495001418	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
595495001419	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
595495001420	purine monophosphate binding site [chemical binding]; other site
595495001421	dimer interface [polypeptide binding]; other site
595495001422	putative catalytic residues [active]
595495001423	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
595495001424	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
595495001425	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
595495001426	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
595495001427	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
595495001428	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
595495001429	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495001430	active site
595495001431	phosphorylation site [posttranslational modification]
595495001432	intermolecular recognition site; other site
595495001433	dimerization interface [polypeptide binding]; other site
595495001434	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495001435	Walker A motif; other site
595495001436	ATP binding site [chemical binding]; other site
595495001437	Walker B motif; other site
595495001438	arginine finger; other site
595495001439	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
595495001440	sensor protein ZraS; Provisional; Region: PRK10364
595495001441	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
595495001442	dimer interface [polypeptide binding]; other site
595495001443	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495001444	ATP binding site [chemical binding]; other site
595495001445	Mg2+ binding site [ion binding]; other site
595495001446	G-X-G motif; other site
595495001447	zinc resistance protein; Provisional; Region: zraP; PRK11546
595495001448	dimer interface [polypeptide binding]; other site
595495001449	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
595495001450	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
595495001451	IHF dimer interface [polypeptide binding]; other site
595495001452	IHF - DNA interface [nucleotide binding]; other site
595495001453	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
595495001454	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
595495001455	Active_site [active]
595495001456	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
595495001457	substrate binding site [chemical binding]; other site
595495001458	active site
595495001459	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
595495001460	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
595495001461	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
595495001462	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
595495001463	putative NADH binding site [chemical binding]; other site
595495001464	putative active site [active]
595495001465	nudix motif; other site
595495001466	putative metal binding site [ion binding]; other site
595495001467	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
595495001468	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
595495001469	ThiC-associated domain; Region: ThiC-associated; pfam13667
595495001470	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
595495001471	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
595495001472	thiamine phosphate binding site [chemical binding]; other site
595495001473	active site
595495001474	pyrophosphate binding site [ion binding]; other site
595495001475	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
595495001476	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
595495001477	ATP binding site [chemical binding]; other site
595495001478	substrate interface [chemical binding]; other site
595495001479	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
595495001480	thiS-thiF/thiG interaction site; other site
595495001481	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
595495001482	ThiS interaction site; other site
595495001483	putative active site [active]
595495001484	tetramer interface [polypeptide binding]; other site
595495001485	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
595495001486	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495001487	FeS/SAM binding site; other site
595495001488	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
595495001489	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
595495001490	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
595495001491	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
595495001492	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
595495001493	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
595495001494	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
595495001495	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
595495001496	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
595495001497	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
595495001498	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
595495001499	DNA binding site [nucleotide binding]
595495001500	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
595495001501	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
595495001502	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
595495001503	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
595495001504	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
595495001505	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
595495001506	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
595495001507	RPB3 interaction site [polypeptide binding]; other site
595495001508	RPB1 interaction site [polypeptide binding]; other site
595495001509	RPB11 interaction site [polypeptide binding]; other site
595495001510	RPB10 interaction site [polypeptide binding]; other site
595495001511	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
595495001512	core dimer interface [polypeptide binding]; other site
595495001513	peripheral dimer interface [polypeptide binding]; other site
595495001514	L10 interface [polypeptide binding]; other site
595495001515	L11 interface [polypeptide binding]; other site
595495001516	putative EF-Tu interaction site [polypeptide binding]; other site
595495001517	putative EF-G interaction site [polypeptide binding]; other site
595495001518	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
595495001519	23S rRNA interface [nucleotide binding]; other site
595495001520	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
595495001521	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
595495001522	mRNA/rRNA interface [nucleotide binding]; other site
595495001523	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
595495001524	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
595495001525	23S rRNA interface [nucleotide binding]; other site
595495001526	L7/L12 interface [polypeptide binding]; other site
595495001527	putative thiostrepton binding site; other site
595495001528	L25 interface [polypeptide binding]; other site
595495001529	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
595495001530	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
595495001531	putative homodimer interface [polypeptide binding]; other site
595495001532	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
595495001533	heterodimer interface [polypeptide binding]; other site
595495001534	homodimer interface [polypeptide binding]; other site
595495001535	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
595495001536	elongation factor Tu; Reviewed; Region: PRK00049
595495001537	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
595495001538	G1 box; other site
595495001539	GEF interaction site [polypeptide binding]; other site
595495001540	GTP/Mg2+ binding site [chemical binding]; other site
595495001541	Switch I region; other site
595495001542	G2 box; other site
595495001543	G3 box; other site
595495001544	Switch II region; other site
595495001545	G4 box; other site
595495001546	G5 box; other site
595495001547	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
595495001548	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
595495001549	Antibiotic Binding Site [chemical binding]; other site
595495001550	pantothenate kinase; Provisional; Region: PRK05439
595495001551	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
595495001552	ATP-binding site [chemical binding]; other site
595495001553	CoA-binding site [chemical binding]; other site
595495001554	Mg2+-binding site [ion binding]; other site
595495001555	Biotin operon repressor [Transcription]; Region: BirA; COG1654
595495001556	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
595495001557	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
595495001558	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
595495001559	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
595495001560	FAD binding domain; Region: FAD_binding_4; pfam01565
595495001561	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
595495001562	glutamate racemase; Provisional; Region: PRK00865
595495001563	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
595495001564	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
595495001565	N-terminal plug; other site
595495001566	ligand-binding site [chemical binding]; other site
595495001567	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
595495001568	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495001569	S-adenosylmethionine binding site [chemical binding]; other site
595495001570	hypothetical protein; Provisional; Region: PRK11056
595495001571	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
595495001572	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
595495001573	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
595495001574	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
595495001575	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
595495001576	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
595495001577	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495001578	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
595495001579	dimerization interface [polypeptide binding]; other site
595495001580	argininosuccinate lyase; Provisional; Region: PRK04833
595495001581	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
595495001582	active sites [active]
595495001583	tetramer interface [polypeptide binding]; other site
595495001584	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
595495001585	nucleotide binding site [chemical binding]; other site
595495001586	N-acetyl-L-glutamate binding site [chemical binding]; other site
595495001587	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
595495001588	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
595495001589	acetylornithine deacetylase; Provisional; Region: PRK05111
595495001590	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
595495001591	metal binding site [ion binding]; metal-binding site
595495001592	putative dimer interface [polypeptide binding]; other site
595495001593	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
595495001594	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
595495001595	hypothetical protein; Provisional; Region: PRK10649
595495001596	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
595495001597	Sulfatase; Region: Sulfatase; pfam00884
595495001598	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
595495001599	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495001600	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
595495001601	active site
595495001602	P-loop; other site
595495001603	phosphorylation site [posttranslational modification]
595495001604	pyruvate formate lyase II activase; Provisional; Region: PRK10076
595495001605	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
595495001606	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
595495001607	dimer interface [polypeptide binding]; other site
595495001608	active site
595495001609	glycine loop; other site
595495001610	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
595495001611	active site
595495001612	P-loop; other site
595495001613	phosphorylation site [posttranslational modification]
595495001614	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
595495001615	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
595495001616	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
595495001617	dimerization domain swap beta strand [polypeptide binding]; other site
595495001618	regulatory protein interface [polypeptide binding]; other site
595495001619	active site
595495001620	regulatory phosphorylation site [posttranslational modification]; other site
595495001621	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
595495001622	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
595495001623	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
595495001624	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
595495001625	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
595495001626	active site
595495001627	phosphorylation site [posttranslational modification]
595495001628	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
595495001629	active site
595495001630	intersubunit interactions; other site
595495001631	catalytic residue [active]
595495001632	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
595495001633	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
595495001634	dimer interface [polypeptide binding]; other site
595495001635	active site
595495001636	metal binding site [ion binding]; metal-binding site
595495001637	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
595495001638	EamA-like transporter family; Region: EamA; pfam00892
595495001639	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
595495001640	EamA-like transporter family; Region: EamA; pfam00892
595495001641	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
595495001642	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
595495001643	heme binding site [chemical binding]; other site
595495001644	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
595495001645	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
595495001646	FAD binding site [chemical binding]; other site
595495001647	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
595495001648	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
595495001649	putative catalytic residues [active]
595495001650	putative nucleotide binding site [chemical binding]; other site
595495001651	putative aspartate binding site [chemical binding]; other site
595495001652	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
595495001653	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
595495001654	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
595495001655	cystathionine gamma-synthase; Provisional; Region: PRK08045
595495001656	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
595495001657	homodimer interface [polypeptide binding]; other site
595495001658	substrate-cofactor binding pocket; other site
595495001659	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495001660	catalytic residue [active]
595495001661	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
595495001662	dimerization interface [polypeptide binding]; other site
595495001663	DNA binding site [nucleotide binding]
595495001664	corepressor binding sites; other site
595495001665	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
595495001666	Transposase; Region: DEDD_Tnp_IS110; pfam01548
595495001667	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
595495001668	hypothetical protein; Provisional; Region: PRK10030
595495001669	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
595495001670	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
595495001671	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
595495001672	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
595495001673	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
595495001674	PAAR motif; Region: PAAR_motif; cl15808
595495001675	RHS Repeat; Region: RHS_repeat; cl11982
595495001676	RHS Repeat; Region: RHS_repeat; pfam05593
595495001677	RHS Repeat; Region: RHS_repeat; cl11982
595495001678	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
595495001679	RHS Repeat; Region: RHS_repeat; pfam05593
595495001680	RHS Repeat; Region: RHS_repeat; pfam05593
595495001681	RHS protein; Region: RHS; pfam03527
595495001682	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
595495001683	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
595495001684	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
595495001685	primosome assembly protein PriA; Validated; Region: PRK05580
595495001686	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
595495001687	ATP binding site [chemical binding]; other site
595495001688	putative Mg++ binding site [ion binding]; other site
595495001689	helicase superfamily c-terminal domain; Region: HELICc; smart00490
595495001690	ATP-binding site [chemical binding]; other site
595495001691	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
595495001692	DNA binding site [nucleotide binding]
595495001693	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
595495001694	domain linker motif; other site
595495001695	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
595495001696	dimerization interface [polypeptide binding]; other site
595495001697	ligand binding site [chemical binding]; other site
595495001698	essential cell division protein FtsN; Provisional; Region: PRK10927
595495001699	cell division protein FtsN; Provisional; Region: PRK12757
595495001700	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
595495001701	active site
595495001702	HslU subunit interaction site [polypeptide binding]; other site
595495001703	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
595495001704	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495001705	Walker A motif; other site
595495001706	ATP binding site [chemical binding]; other site
595495001707	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
595495001708	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
595495001709	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
595495001710	UbiA prenyltransferase family; Region: UbiA; pfam01040
595495001711	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
595495001712	septal ring assembly protein ZapB; Provisional; Region: PRK15422
595495001713	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
595495001714	amphipathic channel; other site
595495001715	Asn-Pro-Ala signature motifs; other site
595495001716	glycerol kinase; Provisional; Region: glpK; PRK00047
595495001717	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
595495001718	N- and C-terminal domain interface [polypeptide binding]; other site
595495001719	active site
595495001720	MgATP binding site [chemical binding]; other site
595495001721	catalytic site [active]
595495001722	metal binding site [ion binding]; metal-binding site
595495001723	glycerol binding site [chemical binding]; other site
595495001724	homotetramer interface [polypeptide binding]; other site
595495001725	homodimer interface [polypeptide binding]; other site
595495001726	FBP binding site [chemical binding]; other site
595495001727	protein IIAGlc interface [polypeptide binding]; other site
595495001728	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
595495001729	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
595495001730	putative active site [active]
595495001731	ferredoxin-NADP reductase; Provisional; Region: PRK10926
595495001732	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
595495001733	FAD binding pocket [chemical binding]; other site
595495001734	FAD binding motif [chemical binding]; other site
595495001735	phosphate binding motif [ion binding]; other site
595495001736	beta-alpha-beta structure motif; other site
595495001737	NAD binding pocket [chemical binding]; other site
595495001738	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
595495001739	Ligand Binding Site [chemical binding]; other site
595495001740	hypothetical protein; Provisional; Region: PRK09981
595495001741	Predicted membrane protein [Function unknown]; Region: COG3152
595495001742	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
595495001743	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
595495001744	triosephosphate isomerase; Provisional; Region: PRK14567
595495001745	substrate binding site [chemical binding]; other site
595495001746	dimer interface [polypeptide binding]; other site
595495001747	catalytic triad [active]
595495001748	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
595495001749	sulfate transporter subunit; Provisional; Region: PRK10752
595495001750	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
595495001751	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
595495001752	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
595495001753	active site
595495001754	ADP/pyrophosphate binding site [chemical binding]; other site
595495001755	dimerization interface [polypeptide binding]; other site
595495001756	allosteric effector site; other site
595495001757	fructose-1,6-bisphosphate binding site; other site
595495001758	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
595495001759	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
595495001760	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
595495001761	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
595495001762	tail protein; Provisional; Region: D; PHA02561
595495001763	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
595495001764	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
595495001765	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
595495001766	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
595495001767	major tail tube protein; Provisional; Region: FII; PHA02600
595495001768	major tail sheath protein; Provisional; Region: FI; PHA02560
595495001769	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
595495001770	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
595495001771	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
595495001772	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
595495001773	phage tail protein, P2 protein I family; Region: tail_P2_I; TIGR01634
595495001774	baseplate assembly protein; Provisional; Region: J; PHA02568
595495001775	baseplate wedge subunit; Provisional; Region: W; PHA02516
595495001776	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
595495001777	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
595495001778	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
595495001779	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
595495001780	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
595495001781	The lysozyme from bacteriophage lambda hydrolyses the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc), as do other lysozymes.  But unlike other lysozymes, bacteriophage lambda does not produce a reducing...; Region: bacteriophage_lambda_lysozyme; cd00736
595495001782	N-acetyl-D-glucosamine binding site [chemical binding]; other site
595495001783	catalytic residue [active]
595495001784	Phage holin family 2; Region: Phage_holin_2; pfam04550
595495001785	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
595495001786	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
595495001787	terminase endonuclease subunit; Provisional; Region: M; PHA02537
595495001788	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
595495001789	Phage major capsid protein, P2 family; Region: Phage_cap_P2; pfam05125
595495001790	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
595495001791	terminase ATPase subunit; Provisional; Region: P; PHA02535
595495001792	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
595495001793	portal vertex protein; Provisional; Region: Q; PHA02536
595495001794	Phage portal protein; Region: Phage_portal; pfam04860
595495001795	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
595495001796	ParB-like nuclease domain; Region: ParB; smart00470
595495001797	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
595495001798	C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145
595495001799	cofactor binding site; other site
595495001800	DNA binding site [nucleotide binding]
595495001801	substrate interaction site [chemical binding]; other site
595495001802	Domain of Unknown Function with PDB structure (DUF3850); Region: DUF3850; pfam12961
595495001803	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
595495001804	DksA-like zinc finger domain containing protein; Region: PHA00080
595495001805	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
595495001806	Regulatory phage protein cox; Region: Phage_Cox; pfam10743
595495001807	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
595495001808	non-specific DNA binding site [nucleotide binding]; other site
595495001809	salt bridge; other site
595495001810	sequence-specific DNA binding site [nucleotide binding]; other site
595495001811	integrase; Provisional; Region: int; PHA02601
595495001812	Phage HP1 integrase, C-terminal catalytic domain. Bacteriophage HP1 and related integrases are found in eubacteria, plasmids and temperate bacteriophages of the P2 family.  They belong to the DNA breaking-rejoining enzyme superfamily, which includes...; Region: HP1_INT_C; cd00797
595495001813	active site
595495001814	catalytic residues [active]
595495001815	Int/Topo IB signature motif; other site
595495001816	dimer interface [polypeptide binding]; other site
595495001817	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
595495001818	dimer interface [polypeptide binding]; other site
595495001819	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
595495001820	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495001821	active site
595495001822	intermolecular recognition site; other site
595495001823	dimerization interface [polypeptide binding]; other site
595495001824	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
595495001825	DNA binding site [nucleotide binding]
595495001826	two-component sensor protein; Provisional; Region: cpxA; PRK09470
595495001827	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
595495001828	dimerization interface [polypeptide binding]; other site
595495001829	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
595495001830	dimer interface [polypeptide binding]; other site
595495001831	phosphorylation site [posttranslational modification]
595495001832	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495001833	ATP binding site [chemical binding]; other site
595495001834	Mg2+ binding site [ion binding]; other site
595495001835	G-X-G motif; other site
595495001836	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
595495001837	MOSC domain; Region: MOSC; pfam03473
595495001838	3-alpha domain; Region: 3-alpha; pfam03475
595495001839	2-keto-3-deoxygluconate transporter; Region: kdgT; TIGR00793
595495001840	superoxide dismutase; Provisional; Region: PRK10925
595495001841	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
595495001842	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
595495001843	L-rhamnose-proton symport protein (RhaT); Region: RhaT; cl05728
595495001844	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
595495001845	transcriptional activator RhaR; Provisional; Region: PRK13500
595495001846	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
595495001847	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495001848	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495001849	transcriptional activator RhaS; Provisional; Region: PRK13503
595495001850	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
595495001851	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495001852	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495001853	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
595495001854	N- and C-terminal domain interface [polypeptide binding]; other site
595495001855	active site
595495001856	putative catalytic site [active]
595495001857	metal binding site [ion binding]; metal-binding site
595495001858	ATP binding site [chemical binding]; other site
595495001859	rhamnulokinase; Provisional; Region: rhaB; PRK10640
595495001860	carbohydrate binding site [chemical binding]; other site
595495001861	L-rhamnose isomerase; Provisional; Region: PRK01076
595495001862	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
595495001863	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
595495001864	intersubunit interface [polypeptide binding]; other site
595495001865	active site
595495001866	Zn2+ binding site [ion binding]; other site
595495001867	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
595495001868	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
595495001869	active site
595495001870	phosphorylation site [posttranslational modification]
595495001871	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
595495001872	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
595495001873	active site
595495001874	P-loop; other site
595495001875	phosphorylation site [posttranslational modification]
595495001876	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
595495001877	putative peptidase; Provisional; Region: PRK09864
595495001878	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
595495001879	oligomer interface [polypeptide binding]; other site
595495001880	active site
595495001881	metal binding site [ion binding]; metal-binding site
595495001882	putative frv operon regulatory protein; Provisional; Region: PRK09863
595495001883	HTH domain; Region: HTH_11; pfam08279
595495001884	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
595495001885	active site
595495001886	phosphorylation site [posttranslational modification]
595495001887	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
595495001888	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
595495001889	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
595495001890	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
595495001891	molybdopterin cofactor binding site; other site
595495001892	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
595495001893	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
595495001894	molybdopterin cofactor binding site; other site
595495001895	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
595495001896	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
595495001897	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
595495001898	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
595495001899	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
595495001900	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
595495001901	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
595495001902	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
595495001903	non-specific DNA binding site [nucleotide binding]; other site
595495001904	salt bridge; other site
595495001905	sequence-specific DNA binding site [nucleotide binding]; other site
595495001906	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
595495001907	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
595495001908	substrate binding pocket [chemical binding]; other site
595495001909	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
595495001910	Coenzyme A binding pocket [chemical binding]; other site
595495001911	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
595495001912	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
595495001913	putative active site [active]
595495001914	dimerization interface [polypeptide binding]; other site
595495001915	putative tRNAtyr binding site [nucleotide binding]; other site
595495001916	hypothetical protein; Reviewed; Region: PRK01637
595495001917	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
595495001918	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495001919	motif II; other site
595495001920	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
595495001921	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
595495001922	putative DNA binding site [nucleotide binding]; other site
595495001923	putative Zn2+ binding site [ion binding]; other site
595495001924	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
595495001925	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
595495001926	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
595495001927	substrate binding site [chemical binding]; other site
595495001928	ATP binding site [chemical binding]; other site
595495001929	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
595495001930	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
595495001931	Tagatose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]; Region: LacD; COG3684
595495001932	catalytic residue [active]
595495001933	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
595495001934	dimerization interface [polypeptide binding]; other site
595495001935	putative active cleft [active]
595495001936	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
595495001937	active site
595495001938	catalytic residues [active]
595495001939	alpha-glucosidase; Provisional; Region: PRK10426
595495001940	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
595495001941	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
595495001942	putative active site [active]
595495001943	putative catalytic site [active]
595495001944	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
595495001945	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
595495001946	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
595495001947	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495001948	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495001949	outer membrane porin L; Provisional; Region: ompL; PRK09980
595495001950	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495001951	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
595495001952	putative transposase OrfB; Reviewed; Region: PHA02517
595495001953	HTH-like domain; Region: HTH_21; pfam13276
595495001954	Integrase core domain; Region: rve; pfam00665
595495001955	Integrase core domain; Region: rve_2; pfam13333
595495001956	Transposase; Region: HTH_Tnp_1; cl17663
595495001957	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
595495001958	Domain of unknown function (DUF932); Region: DUF932; pfam06067
595495001959	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
595495001960	MPN+ (JAMM) motif; other site
595495001961	Zinc-binding site [ion binding]; other site
595495001962	Protein of unknown function (DUF987); Region: DUF987; pfam06174
595495001963	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
595495001964	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
595495001965	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
595495001966	sugar efflux transporter; Region: 2A0120; TIGR00899
595495001967	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495001968	putative substrate translocation pore; other site
595495001969	EamA-like transporter family; Region: EamA; pfam00892
595495001970	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
595495001971	EamA-like transporter family; Region: EamA; pfam00892
595495001972	cytoplasmic membrane lipoprotein-28; Provisional; Region: PRK09861
595495001973	lipoprotein, YaeC family; Region: TIGR00363
595495001974	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
595495001975	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
595495001976	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495001977	putative substrate translocation pore; other site
595495001978	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
595495001979	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
595495001980	cryptic adenine deaminase; Provisional; Region: PRK10027
595495001981	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
595495001982	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
595495001983	active site
595495001984	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
595495001985	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
595495001986	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495001987	putative substrate translocation pore; other site
595495001988	regulatory protein UhpC; Provisional; Region: PRK11663
595495001989	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495001990	putative substrate translocation pore; other site
595495001991	sensory histidine kinase UhpB; Provisional; Region: PRK11644
595495001992	MASE1; Region: MASE1; pfam05231
595495001993	Histidine kinase; Region: HisKA_3; pfam07730
595495001994	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
595495001995	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495001996	active site
595495001997	phosphorylation site [posttranslational modification]
595495001998	intermolecular recognition site; other site
595495001999	dimerization interface [polypeptide binding]; other site
595495002000	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
595495002001	DNA binding residues [nucleotide binding]
595495002002	dimerization interface [polypeptide binding]; other site
595495002003	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
595495002004	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
595495002005	putative valine binding site [chemical binding]; other site
595495002006	dimer interface [polypeptide binding]; other site
595495002007	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
595495002008	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
595495002009	PYR/PP interface [polypeptide binding]; other site
595495002010	dimer interface [polypeptide binding]; other site
595495002011	TPP binding site [chemical binding]; other site
595495002012	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495002013	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
595495002014	TPP-binding site [chemical binding]; other site
595495002015	dimer interface [polypeptide binding]; other site
595495002016	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
595495002017	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495002018	putative substrate translocation pore; other site
595495002019	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
595495002020	Domain of unknown function (DUF202); Region: DUF202; pfam02656
595495002021	Predicted membrane protein [Function unknown]; Region: COG2149
595495002022	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
595495002023	Sulfatase; Region: Sulfatase; pfam00884
595495002024	putative transporter; Provisional; Region: PRK10484
595495002025	uncharacterized SLC5 subfamily, Escherichia coli YidK-like; solute binding domain; Region: SLC5sbd_YidK; cd10328
595495002026	Na binding site [ion binding]; other site
595495002027	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
595495002028	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495002029	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
595495002030	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
595495002031	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
595495002032	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
595495002033	NAD(P) binding site [chemical binding]; other site
595495002034	LDH/MDH dimer interface [polypeptide binding]; other site
595495002035	substrate binding site [chemical binding]; other site
595495002036	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
595495002037	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
595495002038	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
595495002039	active site turn [active]
595495002040	phosphorylation site [posttranslational modification]
595495002041	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
595495002042	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
595495002043	DNA-binding site [nucleotide binding]; DNA binding site
595495002044	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
595495002045	putative transporter; Validated; Region: PRK03818
595495002046	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
595495002047	TrkA-C domain; Region: TrkA_C; pfam02080
595495002048	TrkA-C domain; Region: TrkA_C; pfam02080
595495002049	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
595495002050	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
595495002051	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
595495002052	putative dimer interface [polypeptide binding]; other site
595495002053	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
595495002054	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
595495002055	putative dimer interface [polypeptide binding]; other site
595495002056	hypothetical protein; Provisional; Region: PRK11616
595495002057	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
595495002058	putative oxidoreductase; Provisional; Region: PRK11445
595495002059	hypothetical protein; Provisional; Region: PRK07236
595495002060	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495002061	D-galactonate transporter; Region: 2A0114; TIGR00893
595495002062	putative substrate translocation pore; other site
595495002063	galactonate dehydratase; Provisional; Region: PRK14017
595495002064	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
595495002065	putative active site pocket [active]
595495002066	putative metal binding site [ion binding]; other site
595495002067	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
595495002068	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
595495002069	active site
595495002070	intersubunit interface [polypeptide binding]; other site
595495002071	catalytic residue [active]
595495002072	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
595495002073	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
595495002074	Transcriptional regulators [Transcription]; Region: FadR; COG2186
595495002075	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
595495002076	DNA-binding site [nucleotide binding]; DNA binding site
595495002077	FCD domain; Region: FCD; pfam07729
595495002078	hypothetical protein; Provisional; Region: PRK10215
595495002079	sugar phosphate phosphatase; Provisional; Region: PRK10513
595495002080	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495002081	active site
595495002082	motif I; other site
595495002083	motif II; other site
595495002084	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495002085	hypothetical protein; Provisional; Region: PRK11426
595495002086	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
595495002087	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495002088	Mg2+ binding site [ion binding]; other site
595495002089	G-X-G motif; other site
595495002090	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
595495002091	anchoring element; other site
595495002092	dimer interface [polypeptide binding]; other site
595495002093	ATP binding site [chemical binding]; other site
595495002094	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
595495002095	active site
595495002096	putative metal-binding site [ion binding]; other site
595495002097	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
595495002098	recF protein; Region: recf; TIGR00611
595495002099	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495002100	Walker A/P-loop; other site
595495002101	ATP binding site [chemical binding]; other site
595495002102	Q-loop/lid; other site
595495002103	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495002104	ABC transporter signature motif; other site
595495002105	Walker B; other site
595495002106	D-loop; other site
595495002107	H-loop/switch region; other site
595495002108	DNA polymerase III subunit beta; Validated; Region: PRK05643
595495002109	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
595495002110	putative DNA binding surface [nucleotide binding]; other site
595495002111	dimer interface [polypeptide binding]; other site
595495002112	beta-clamp/clamp loader binding surface; other site
595495002113	beta-clamp/translesion DNA polymerase binding surface; other site
595495002114	DnaA N-terminal domain; Region: DnaA_N; pfam11638
595495002115	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
595495002116	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495002117	Walker A motif; other site
595495002118	ATP binding site [chemical binding]; other site
595495002119	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
595495002120	Walker B motif; other site
595495002121	arginine finger; other site
595495002122	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
595495002123	DnaA box-binding interface [nucleotide binding]; other site
595495002124	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
595495002125	ribonuclease P; Reviewed; Region: rnpA; PRK01732
595495002126	hypothetical protein; Validated; Region: PRK00041
595495002127	membrane protein insertase; Provisional; Region: PRK01318
595495002128	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
595495002129	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
595495002130	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
595495002131	trmE is a tRNA modification GTPase; Region: trmE; cd04164
595495002132	G1 box; other site
595495002133	GTP/Mg2+ binding site [chemical binding]; other site
595495002134	Switch I region; other site
595495002135	G2 box; other site
595495002136	Switch II region; other site
595495002137	G3 box; other site
595495002138	G4 box; other site
595495002139	G5 box; other site
595495002140	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
595495002141	Tryptophanese operon leader peptide; Region: Tna_leader; pfam08053
595495002142	tryptophanase, leader peptide-associated; Region: tnaA_trp_ase; TIGR02617
595495002143	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
595495002144	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
595495002145	catalytic residue [active]
595495002146	tryptophan permease TnaB; Provisional; Region: PRK09664
595495002147	aromatic amino acid transport protein; Region: araaP; TIGR00837
595495002148	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495002149	putative substrate translocation pore; other site
595495002150	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495002151	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
595495002152	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
595495002153	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495002154	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
595495002155	substrate binding pocket [chemical binding]; other site
595495002156	dimerization interface [polypeptide binding]; other site
595495002157	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
595495002158	Predicted flavoprotein [General function prediction only]; Region: COG0431
595495002159	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
595495002160	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
595495002161	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
595495002162	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495002163	active site
595495002164	motif I; other site
595495002165	motif II; other site
595495002166	putative inner membrane protein; Provisional; Region: PRK09823
595495002167	Uncharacterized protein family (UPF0167); Region: UPF0167; cl01252
595495002168	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
595495002169	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
595495002170	active site
595495002171	trimer interface [polypeptide binding]; other site
595495002172	allosteric site; other site
595495002173	active site lid [active]
595495002174	N-terminal Early set domain associated with the catalytic domain of putative esterases; Region: E_set_Esterase_like_N; cd11294
595495002175	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
595495002176	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
595495002177	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
595495002178	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
595495002179	trimer interface; other site
595495002180	sugar binding site [chemical binding]; other site
595495002181	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
595495002182	beta-galactosidase; Region: BGL; TIGR03356
595495002183	PTS system beta-glucoside-specific transporter subunits IIABC; Provisional; Region: PRK09824
595495002184	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
595495002185	active site turn [active]
595495002186	phosphorylation site [posttranslational modification]
595495002187	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
595495002188	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
595495002189	HPr interaction site; other site
595495002190	glycerol kinase (GK) interaction site [polypeptide binding]; other site
595495002191	active site
595495002192	phosphorylation site [posttranslational modification]
595495002193	transcriptional antiterminator BglG; Provisional; Region: PRK09772
595495002194	CAT RNA binding domain; Region: CAT_RBD; pfam03123
595495002195	PRD domain; Region: PRD; pfam00874
595495002196	PRD domain; Region: PRD; pfam00874
595495002197	transcriptional regulator PhoU; Provisional; Region: PRK11115
595495002198	PhoU domain; Region: PhoU; pfam01895
595495002199	PhoU domain; Region: PhoU; pfam01895
595495002200	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
595495002201	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
595495002202	Walker A/P-loop; other site
595495002203	ATP binding site [chemical binding]; other site
595495002204	Q-loop/lid; other site
595495002205	ABC transporter signature motif; other site
595495002206	Walker B; other site
595495002207	D-loop; other site
595495002208	H-loop/switch region; other site
595495002209	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
595495002210	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495002211	dimer interface [polypeptide binding]; other site
595495002212	conserved gate region; other site
595495002213	putative PBP binding loops; other site
595495002214	ABC-ATPase subunit interface; other site
595495002215	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
595495002216	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495002217	dimer interface [polypeptide binding]; other site
595495002218	conserved gate region; other site
595495002219	putative PBP binding loops; other site
595495002220	ABC-ATPase subunit interface; other site
595495002221	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
595495002222	Fimbrial protein; Region: Fimbrial; cl01416
595495002223	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
595495002224	PapC N-terminal domain; Region: PapC_N; pfam13954
595495002225	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
595495002226	PapC C-terminal domain; Region: PapC_C; pfam13953
595495002227	fimbrial chaperone protein; Provisional; Region: lfpB; PRK15290
595495002228	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
595495002229	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
595495002230	fimbrial protein; Provisional; Region: lpfA; PRK15289
595495002231	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
595495002232	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
595495002233	glutaminase active site [active]
595495002234	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
595495002235	dimer interface [polypeptide binding]; other site
595495002236	active site
595495002237	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
595495002238	dimer interface [polypeptide binding]; other site
595495002239	active site
595495002240	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
595495002241	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
595495002242	Substrate binding site; other site
595495002243	Mg++ binding site; other site
595495002244	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
595495002245	active site
595495002246	substrate binding site [chemical binding]; other site
595495002247	CoA binding site [chemical binding]; other site
595495002248	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
595495002249	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
595495002250	gamma subunit interface [polypeptide binding]; other site
595495002251	epsilon subunit interface [polypeptide binding]; other site
595495002252	LBP interface [polypeptide binding]; other site
595495002253	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
595495002254	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
595495002255	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
595495002256	alpha subunit interaction interface [polypeptide binding]; other site
595495002257	Walker A motif; other site
595495002258	ATP binding site [chemical binding]; other site
595495002259	Walker B motif; other site
595495002260	inhibitor binding site; inhibition site
595495002261	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
595495002262	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
595495002263	core domain interface [polypeptide binding]; other site
595495002264	delta subunit interface [polypeptide binding]; other site
595495002265	epsilon subunit interface [polypeptide binding]; other site
595495002266	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
595495002267	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
595495002268	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
595495002269	beta subunit interaction interface [polypeptide binding]; other site
595495002270	Walker A motif; other site
595495002271	ATP binding site [chemical binding]; other site
595495002272	Walker B motif; other site
595495002273	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
595495002274	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
595495002275	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
595495002276	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
595495002277	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
595495002278	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
595495002279	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
595495002280	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
595495002281	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
595495002282	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
595495002283	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495002284	S-adenosylmethionine binding site [chemical binding]; other site
595495002285	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
595495002286	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
595495002287	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
595495002288	FMN-binding protein MioC; Provisional; Region: PRK09004
595495002289	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
595495002290	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
595495002291	putative DNA binding site [nucleotide binding]; other site
595495002292	putative Zn2+ binding site [ion binding]; other site
595495002293	AsnC family; Region: AsnC_trans_reg; pfam01037
595495002294	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
595495002295	dimer interface [polypeptide binding]; other site
595495002296	active site
595495002297	hypothetical protein; Provisional; Region: yieM; PRK10997
595495002298	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
595495002299	metal ion-dependent adhesion site (MIDAS); other site
595495002300	regulatory ATPase RavA; Provisional; Region: PRK13531
595495002301	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495002302	Walker A motif; other site
595495002303	ATP binding site [chemical binding]; other site
595495002304	Walker B motif; other site
595495002305	arginine finger; other site
595495002306	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
595495002307	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
595495002308	potassium uptake protein; Region: kup; TIGR00794
595495002309	D-ribose pyranase; Provisional; Region: PRK11797
595495002310	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
595495002311	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
595495002312	Walker A/P-loop; other site
595495002313	ATP binding site [chemical binding]; other site
595495002314	Q-loop/lid; other site
595495002315	ABC transporter signature motif; other site
595495002316	Walker B; other site
595495002317	D-loop; other site
595495002318	H-loop/switch region; other site
595495002319	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
595495002320	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
595495002321	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
595495002322	putative transporter; Provisional; Region: PRK10504
595495002323	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495002324	putative substrate translocation pore; other site
595495002325	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495002326	Transcriptional regulators [Transcription]; Region: FadR; COG2186
595495002327	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
595495002328	DNA-binding site [nucleotide binding]; DNA binding site
595495002329	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
595495002330	transcriptional regulator HdfR; Provisional; Region: PRK03601
595495002331	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495002332	LysR substrate binding domain; Region: LysR_substrate; pfam03466
595495002333	dimerization interface [polypeptide binding]; other site
595495002334	hypothetical protein; Provisional; Region: PRK11027
595495002335	putative ATP-dependent protease; Provisional; Region: PRK09862
595495002336	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
595495002337	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495002338	Walker A motif; other site
595495002339	ATP binding site [chemical binding]; other site
595495002340	Walker B motif; other site
595495002341	arginine finger; other site
595495002342	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
595495002343	ilvG operon leader peptide; Provisional; Region: PRK10424
595495002344	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
595495002345	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
595495002346	PYR/PP interface [polypeptide binding]; other site
595495002347	dimer interface [polypeptide binding]; other site
595495002348	TPP binding site [chemical binding]; other site
595495002349	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495002350	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
595495002351	TPP-binding site [chemical binding]; other site
595495002352	dimer interface [polypeptide binding]; other site
595495002353	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
595495002354	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
595495002355	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
595495002356	homodimer interface [polypeptide binding]; other site
595495002357	substrate-cofactor binding pocket; other site
595495002358	catalytic residue [active]
595495002359	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
595495002360	threonine dehydratase; Reviewed; Region: PRK09224
595495002361	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
595495002362	tetramer interface [polypeptide binding]; other site
595495002363	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495002364	catalytic residue [active]
595495002365	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
595495002366	putative Ile/Val binding site [chemical binding]; other site
595495002367	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
595495002368	putative Ile/Val binding site [chemical binding]; other site
595495002369	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495002370	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
595495002371	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
595495002372	putative dimerization interface [polypeptide binding]; other site
595495002373	ketol-acid reductoisomerase; Validated; Region: PRK05225
595495002374	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
595495002375	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
595495002376	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
595495002377	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
595495002378	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
595495002379	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3692
595495002380	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
595495002381	Part of AAA domain; Region: AAA_19; pfam13245
595495002382	Family description; Region: UvrD_C_2; pfam13538
595495002383	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
595495002384	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
595495002385	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
595495002386	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
595495002387	ATP binding site [chemical binding]; other site
595495002388	Mg++ binding site [ion binding]; other site
595495002389	motif III; other site
595495002390	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
595495002391	nucleotide binding region [chemical binding]; other site
595495002392	ATP-binding site [chemical binding]; other site
595495002393	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
595495002394	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
595495002395	catalytic residues [active]
595495002396	putative rho operon leader peptide; Provisional; Region: PRK09979
595495002397	transcription termination factor Rho; Provisional; Region: rho; PRK09376
595495002398	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
595495002399	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
595495002400	RNA binding site [nucleotide binding]; other site
595495002401	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
595495002402	multimer interface [polypeptide binding]; other site
595495002403	Walker A motif; other site
595495002404	ATP binding site [chemical binding]; other site
595495002405	Walker B motif; other site
595495002406	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
595495002407	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
595495002408	Mg++ binding site [ion binding]; other site
595495002409	putative catalytic motif [active]
595495002410	substrate binding site [chemical binding]; other site
595495002411	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
595495002412	Chain length determinant protein; Region: Wzz; pfam02706
595495002413	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
595495002414	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
595495002415	active site
595495002416	homodimer interface [polypeptide binding]; other site
595495002417	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
595495002418	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
595495002419	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
595495002420	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
595495002421	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
595495002422	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
595495002423	NAD binding site [chemical binding]; other site
595495002424	substrate binding site [chemical binding]; other site
595495002425	homodimer interface [polypeptide binding]; other site
595495002426	active site
595495002427	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
595495002428	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
595495002429	substrate binding site; other site
595495002430	tetramer interface; other site
595495002431	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
595495002432	Coenzyme A binding pocket [chemical binding]; other site
595495002433	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
595495002434	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
595495002435	inhibitor-cofactor binding pocket; inhibition site
595495002436	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495002437	catalytic residue [active]
595495002438	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
595495002439	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
595495002440	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
595495002441	putative common antigen polymerase; Provisional; Region: PRK02975
595495002442	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
595495002443	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
595495002444	putative transport protein YifK; Provisional; Region: PRK10746
595495002445	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
595495002446	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495002447	FeS/SAM binding site; other site
595495002448	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
595495002449	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
595495002450	HemY protein N-terminus; Region: HemY_N; pfam07219
595495002451	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
595495002452	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
595495002453	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
595495002454	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
595495002455	active site
595495002456	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
595495002457	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
595495002458	domain interfaces; other site
595495002459	active site
595495002460	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
595495002461	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
595495002462	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
595495002463	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
595495002464	putative iron binding site [ion binding]; other site
595495002465	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
595495002466	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
595495002467	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
595495002468	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
595495002469	hypothetical protein; Provisional; Region: PRK10963
595495002470	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
595495002471	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
595495002472	active site
595495002473	DNA binding site [nucleotide binding]
595495002474	Int/Topo IB signature motif; other site
595495002475	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
595495002476	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495002477	motif II; other site
595495002478	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
595495002479	Part of AAA domain; Region: AAA_19; pfam13245
595495002480	Family description; Region: UvrD_C_2; pfam13538
595495002481	Predicted periplasmic protein [Function unknown]; Region: COG3698
595495002482	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
595495002483	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
595495002484	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
595495002485	Cl binding site [ion binding]; other site
595495002486	oligomer interface [polypeptide binding]; other site
595495002487	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
595495002488	Protein of unknown function (DUF3289); Region: DUF3289; cl11840
595495002489	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495002490	Protein of unknown function (DUF3289); Region: DUF3289; cl11840
595495002491	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
595495002492	EamA-like transporter family; Region: EamA; cl17759
595495002493	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
595495002494	CoenzymeA binding site [chemical binding]; other site
595495002495	subunit interaction site [polypeptide binding]; other site
595495002496	PHB binding site; other site
595495002497	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
595495002498	dimerization interface [polypeptide binding]; other site
595495002499	substrate binding site [chemical binding]; other site
595495002500	active site
595495002501	calcium binding site [ion binding]; other site
595495002502	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
595495002503	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
595495002504	ATP binding site [chemical binding]; other site
595495002505	putative Mg++ binding site [ion binding]; other site
595495002506	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
595495002507	nucleotide binding region [chemical binding]; other site
595495002508	ATP-binding site [chemical binding]; other site
595495002509	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
595495002510	Helicase and RNase D C-terminal; Region: HRDC; smart00341
595495002511	threonine efflux system; Provisional; Region: PRK10229
595495002512	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
595495002513	lysophospholipase L2; Provisional; Region: PRK10749
595495002514	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
595495002515	putative hydrolase; Provisional; Region: PRK10976
595495002516	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495002517	active site
595495002518	motif I; other site
595495002519	motif II; other site
595495002520	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495002521	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
595495002522	EamA-like transporter family; Region: EamA; pfam00892
595495002523	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
595495002524	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495002525	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
595495002526	putative dimerization interface [polypeptide binding]; other site
595495002527	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
595495002528	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
595495002529	THF binding site; other site
595495002530	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
595495002531	substrate binding site [chemical binding]; other site
595495002532	THF binding site; other site
595495002533	zinc-binding site [ion binding]; other site
595495002534	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
595495002535	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
595495002536	uridine phosphorylase; Provisional; Region: PRK11178
595495002537	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
595495002538	DNA recombination protein RmuC; Provisional; Region: PRK10361
595495002539	RmuC family; Region: RmuC; pfam02646
595495002540	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
595495002541	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495002542	S-adenosylmethionine binding site [chemical binding]; other site
595495002543	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
595495002544	SCP-2 sterol transfer family; Region: SCP2; pfam02036
595495002545	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
595495002546	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
595495002547	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
595495002548	twin arginine translocase protein A; Provisional; Region: tatA; PRK00575
595495002549	sec-independent translocase; Provisional; Region: PRK01770
595495002550	sec-independent translocase; Provisional; Region: tatB; PRK00404
595495002551	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
595495002552	potential frameshift: common BLAST hit: gi|260870563|ref|YP_003236965.1| DNase TatD
595495002553	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
595495002554	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
595495002555	active site
595495002556	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
595495002557	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
595495002558	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
595495002559	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
595495002560	FMN reductase; Validated; Region: fre; PRK08051
595495002561	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
595495002562	FAD binding pocket [chemical binding]; other site
595495002563	FAD binding motif [chemical binding]; other site
595495002564	phosphate binding motif [ion binding]; other site
595495002565	beta-alpha-beta structure motif; other site
595495002566	NAD binding pocket [chemical binding]; other site
595495002567	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
595495002568	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
595495002569	dimer interface [polypeptide binding]; other site
595495002570	active site
595495002571	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
595495002572	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
595495002573	substrate binding site [chemical binding]; other site
595495002574	oxyanion hole (OAH) forming residues; other site
595495002575	trimer interface [polypeptide binding]; other site
595495002576	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
595495002577	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
595495002578	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
595495002579	proline dipeptidase; Provisional; Region: PRK13607
595495002580	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
595495002581	active site
595495002582	hypothetical protein; Provisional; Region: PRK11568
595495002583	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
595495002584	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
595495002585	potassium transporter; Provisional; Region: PRK10750
595495002586	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
595495002587	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
595495002588	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
595495002589	Walker A motif; other site
595495002590	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
595495002591	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
595495002592	GTP binding site; other site
595495002593	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
595495002594	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
595495002595	serine/threonine protein kinase; Provisional; Region: PRK11768
595495002596	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
595495002597	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
595495002598	catalytic residues [active]
595495002599	hinge region; other site
595495002600	alpha helical domain; other site
595495002601	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
595495002602	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495002603	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
595495002604	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
595495002605	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
595495002606	putative acyl-acceptor binding pocket; other site
595495002607	DNA polymerase I; Provisional; Region: PRK05755
595495002608	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
595495002609	active site
595495002610	metal binding site 1 [ion binding]; metal-binding site
595495002611	putative 5' ssDNA interaction site; other site
595495002612	metal binding site 3; metal-binding site
595495002613	metal binding site 2 [ion binding]; metal-binding site
595495002614	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
595495002615	putative DNA binding site [nucleotide binding]; other site
595495002616	putative metal binding site [ion binding]; other site
595495002617	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
595495002618	active site
595495002619	catalytic site [active]
595495002620	substrate binding site [chemical binding]; other site
595495002621	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
595495002622	active site
595495002623	DNA binding site [nucleotide binding]
595495002624	catalytic site [active]
595495002625	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
595495002626	G1 box; other site
595495002627	GTP/Mg2+ binding site [chemical binding]; other site
595495002628	Switch I region; other site
595495002629	G2 box; other site
595495002630	G3 box; other site
595495002631	Switch II region; other site
595495002632	G4 box; other site
595495002633	G5 box; other site
595495002634	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
595495002635	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
595495002636	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495002637	FeS/SAM binding site; other site
595495002638	HemN C-terminal domain; Region: HemN_C; pfam06969
595495002639	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
595495002640	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495002641	active site
595495002642	phosphorylation site [posttranslational modification]
595495002643	intermolecular recognition site; other site
595495002644	dimerization interface [polypeptide binding]; other site
595495002645	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495002646	Walker A motif; other site
595495002647	ATP binding site [chemical binding]; other site
595495002648	Walker B motif; other site
595495002649	arginine finger; other site
595495002650	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
595495002651	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
595495002652	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
595495002653	putative active site [active]
595495002654	heme pocket [chemical binding]; other site
595495002655	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
595495002656	dimer interface [polypeptide binding]; other site
595495002657	phosphorylation site [posttranslational modification]
595495002658	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495002659	ATP binding site [chemical binding]; other site
595495002660	Mg2+ binding site [ion binding]; other site
595495002661	G-X-G motif; other site
595495002662	glutamine synthetase; Provisional; Region: glnA; PRK09469
595495002663	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
595495002664	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
595495002665	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
595495002666	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
595495002667	G1 box; other site
595495002668	putative GEF interaction site [polypeptide binding]; other site
595495002669	GTP/Mg2+ binding site [chemical binding]; other site
595495002670	Switch I region; other site
595495002671	G2 box; other site
595495002672	G3 box; other site
595495002673	Switch II region; other site
595495002674	G4 box; other site
595495002675	G5 box; other site
595495002676	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
595495002677	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
595495002678	transcriptional regulator protein; Region: phnR; TIGR03337
595495002679	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
595495002680	DNA-binding site [nucleotide binding]; DNA binding site
595495002681	UTRA domain; Region: UTRA; pfam07702
595495002682	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
595495002683	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495002684	putative substrate translocation pore; other site
595495002685	phosphoglycerate transporter family protein; Region: 2A0104; TIGR00881
595495002686	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495002687	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
595495002688	AAA ATPase domain; Region: AAA_15; pfam13175
595495002689	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495002690	Walker A/P-loop; other site
595495002691	ATP binding site [chemical binding]; other site
595495002692	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
595495002693	putative active site [active]
595495002694	putative metal-binding site [ion binding]; other site
595495002695	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
595495002696	Part of AAA domain; Region: AAA_19; pfam13245
595495002697	Family description; Region: UvrD_C_2; pfam13538
595495002698	integrase; Provisional; Region: PRK09692
595495002699	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
595495002700	active site
595495002701	Int/Topo IB signature motif; other site
595495002702	putative transporter; Provisional; Region: PRK11462
595495002703	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
595495002704	putative alpha-glucosidase; Provisional; Region: PRK10658
595495002705	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
595495002706	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
595495002707	active site
595495002708	homotrimer interface [polypeptide binding]; other site
595495002709	catalytic site [active]
595495002710	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
595495002711	AsmA family; Region: AsmA; pfam05170
595495002712	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
595495002713	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
595495002714	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
595495002715	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
595495002716	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
595495002717	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
595495002718	generic binding surface II; other site
595495002719	ssDNA binding site; other site
595495002720	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
595495002721	ATP binding site [chemical binding]; other site
595495002722	putative Mg++ binding site [ion binding]; other site
595495002723	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
595495002724	nucleotide binding region [chemical binding]; other site
595495002725	ATP-binding site [chemical binding]; other site
595495002726	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
595495002727	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
595495002728	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
595495002729	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
595495002730	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
595495002731	Zn2+ binding site [ion binding]; other site
595495002732	Mg2+ binding site [ion binding]; other site
595495002733	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
595495002734	synthetase active site [active]
595495002735	NTP binding site [chemical binding]; other site
595495002736	metal binding site [ion binding]; metal-binding site
595495002737	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
595495002738	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
595495002739	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
595495002740	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
595495002741	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
595495002742	catalytic site [active]
595495002743	G-X2-G-X-G-K; other site
595495002744	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
595495002745	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
595495002746	nucleotide binding pocket [chemical binding]; other site
595495002747	K-X-D-G motif; other site
595495002748	catalytic site [active]
595495002749	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
595495002750	Predicted membrane protein [Function unknown]; Region: COG2860
595495002751	UPF0126 domain; Region: UPF0126; pfam03458
595495002752	UPF0126 domain; Region: UPF0126; pfam03458
595495002753	DNA-damage-inducible protein D; Provisional; Region: dinD; PRK11525
595495002754	BRO family, N-terminal domain; Region: Bro-N; pfam02498
595495002755	hypothetical protein; Provisional; Region: PRK11820
595495002756	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
595495002757	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
595495002758	ribonuclease PH; Reviewed; Region: rph; PRK00173
595495002759	Ribonuclease PH; Region: RNase_PH_bact; cd11362
595495002760	hexamer interface [polypeptide binding]; other site
595495002761	active site
595495002762	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
595495002763	active site
595495002764	division inhibitor protein; Provisional; Region: slmA; PRK09480
595495002765	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
595495002766	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
595495002767	trimer interface [polypeptide binding]; other site
595495002768	active site
595495002769	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
595495002770	Flavoprotein; Region: Flavoprotein; pfam02441
595495002771	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
595495002772	hypothetical protein; Reviewed; Region: PRK00024
595495002773	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
595495002774	MPN+ (JAMM) motif; other site
595495002775	Zinc-binding site [ion binding]; other site
595495002776	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
595495002777	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
595495002778	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
595495002779	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
595495002780	DNA binding site [nucleotide binding]
595495002781	catalytic residue [active]
595495002782	H2TH interface [polypeptide binding]; other site
595495002783	putative catalytic residues [active]
595495002784	turnover-facilitating residue; other site
595495002785	intercalation triad [nucleotide binding]; other site
595495002786	8OG recognition residue [nucleotide binding]; other site
595495002787	putative reading head residues; other site
595495002788	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
595495002789	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
595495002790	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
595495002791	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
595495002792	active site
595495002793	(T/H)XGH motif; other site
595495002794	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
595495002795	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
595495002796	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
595495002797	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
595495002798	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
595495002799	putative active site [active]
595495002800	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
595495002801	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
595495002802	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
595495002803	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
595495002804	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
595495002805	Ligand binding site; other site
595495002806	metal-binding site
595495002807	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
595495002808	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
595495002809	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
595495002810	Ligand binding site; other site
595495002811	metal-binding site
595495002812	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
595495002813	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; pfam06176
595495002814	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
595495002815	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
595495002816	Ligand binding site; other site
595495002817	metal-binding site
595495002818	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
595495002819	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
595495002820	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
595495002821	active site
595495002822	O-Antigen ligase; Region: Wzy_C; pfam04932
595495002823	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
595495002824	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
595495002825	putative active site [active]
595495002826	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
595495002827	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
595495002828	putative active site [active]
595495002829	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
595495002830	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
595495002831	NADP binding site [chemical binding]; other site
595495002832	homopentamer interface [polypeptide binding]; other site
595495002833	substrate binding site [chemical binding]; other site
595495002834	active site
595495002835	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
595495002836	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
595495002837	substrate-cofactor binding pocket; other site
595495002838	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495002839	catalytic residue [active]
595495002840	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
595495002841	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
595495002842	NAD(P) binding site [chemical binding]; other site
595495002843	putative glycosyl transferase; Provisional; Region: PRK10073
595495002844	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
595495002845	active site
595495002846	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
595495002847	NodB motif; other site
595495002848	putative active site [active]
595495002849	putative catalytic site [active]
595495002850	Zn binding site [ion binding]; other site
595495002851	AmiB activator; Provisional; Region: PRK11637
595495002852	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
595495002853	Peptidase family M23; Region: Peptidase_M23; pfam01551
595495002854	phosphoglyceromutase; Provisional; Region: PRK05434
595495002855	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
595495002856	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
595495002857	active site residue [active]
595495002858	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
595495002859	GSH binding site [chemical binding]; other site
595495002860	catalytic residues [active]
595495002861	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
595495002862	SecA binding site; other site
595495002863	Preprotein binding site; other site
595495002864	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
595495002865	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
595495002866	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
595495002867	serine acetyltransferase; Provisional; Region: cysE; PRK11132
595495002868	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
595495002869	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
595495002870	trimer interface [polypeptide binding]; other site
595495002871	active site
595495002872	substrate binding site [chemical binding]; other site
595495002873	CoA binding site [chemical binding]; other site
595495002874	putative rRNA methylase; Provisional; Region: PRK10358
595495002875	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
595495002876	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
595495002877	phosphate binding site [ion binding]; other site
595495002878	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
595495002879	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
595495002880	DNA-binding site [nucleotide binding]; DNA binding site
595495002881	FCD domain; Region: FCD; pfam07729
595495002882	L-lactate permease; Provisional; Region: PRK10420
595495002883	glycolate transporter; Provisional; Region: PRK09695
595495002884	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
595495002885	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
595495002886	trimer interface [polypeptide binding]; other site
595495002887	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
595495002888	trimer interface [polypeptide binding]; other site
595495002889	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
595495002890	Haemagglutinin; Region: HIM; pfam05662
595495002891	Haemagglutinin; Region: HIM; pfam05662
595495002892	YadA-like C-terminal region; Region: YadA; pfam03895
595495002893	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
595495002894	hypothetical protein; Provisional; Region: PRK11020
595495002895	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
595495002896	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
595495002897	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
595495002898	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
595495002899	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
595495002900	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
595495002901	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
595495002902	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
595495002903	active site
595495002904	P-loop; other site
595495002905	phosphorylation site [posttranslational modification]
595495002906	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
595495002907	active site
595495002908	phosphorylation site [posttranslational modification]
595495002909	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
595495002910	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
595495002911	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
595495002912	HlyD family secretion protein; Region: HlyD_3; pfam13437
595495002913	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
595495002914	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
595495002915	RHS protein; Region: RHS; pfam03527
595495002916	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
595495002917	putative lyase; Provisional; Region: PRK09687
595495002918	PAAR motif; Region: PAAR_motif; cl15808
595495002919	RHS Repeat; Region: RHS_repeat; pfam05593
595495002920	RHS Repeat; Region: RHS_repeat; pfam05593
595495002921	RHS Repeat; Region: RHS_repeat; cl11982
595495002922	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
595495002923	RHS Repeat; Region: RHS_repeat; pfam05593
595495002924	RHS Repeat; Region: RHS_repeat; pfam05593
595495002925	RHS protein; Region: RHS; pfam03527
595495002926	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
595495002927	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
595495002928	putative glutathione S-transferase; Provisional; Region: PRK10357
595495002929	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
595495002930	putative C-terminal domain interface [polypeptide binding]; other site
595495002931	putative GSH binding site (G-site) [chemical binding]; other site
595495002932	putative dimer interface [polypeptide binding]; other site
595495002933	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
595495002934	dimer interface [polypeptide binding]; other site
595495002935	N-terminal domain interface [polypeptide binding]; other site
595495002936	putative substrate binding pocket (H-site) [chemical binding]; other site
595495002937	selenocysteine synthase; Provisional; Region: PRK04311
595495002938	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
595495002939	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
595495002940	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
595495002941	catalytic residue [active]
595495002942	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
595495002943	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
595495002944	G1 box; other site
595495002945	putative GEF interaction site [polypeptide binding]; other site
595495002946	GTP/Mg2+ binding site [chemical binding]; other site
595495002947	Switch I region; other site
595495002948	G2 box; other site
595495002949	G3 box; other site
595495002950	Switch II region; other site
595495002951	G4 box; other site
595495002952	G5 box; other site
595495002953	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
595495002954	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
595495002955	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
595495002956	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
595495002957	putative alcohol dehydrogenase; Provisional; Region: PRK09860
595495002958	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495002959	dimer interface [polypeptide binding]; other site
595495002960	active site
595495002961	metal binding site [ion binding]; metal-binding site
595495002962	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
595495002963	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
595495002964	NAD(P) binding site [chemical binding]; other site
595495002965	catalytic residues [active]
595495002966	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
595495002967	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
595495002968	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
595495002969	HlyD family secretion protein; Region: HlyD_3; pfam13437
595495002970	Transcriptional regulator [Transcription]; Region: LysR; COG0583
595495002971	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495002972	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
595495002973	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
595495002974	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
595495002975	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
595495002976	intersubunit interface [polypeptide binding]; other site
595495002977	active site
595495002978	Zn2+ binding site [ion binding]; other site
595495002979	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
595495002980	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
595495002981	AP (apurinic/apyrimidinic) site pocket; other site
595495002982	DNA interaction; other site
595495002983	Metal-binding active site; metal-binding site
595495002984	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
595495002985	active site
595495002986	dimer interface [polypeptide binding]; other site
595495002987	magnesium binding site [ion binding]; other site
595495002988	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
595495002989	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
595495002990	putative N- and C-terminal domain interface [polypeptide binding]; other site
595495002991	putative active site [active]
595495002992	MgATP binding site [chemical binding]; other site
595495002993	catalytic site [active]
595495002994	metal binding site [ion binding]; metal-binding site
595495002995	putative xylulose binding site [chemical binding]; other site
595495002996	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
595495002997	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
595495002998	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
595495002999	DctM-like transporters; Region: DctM; pfam06808
595495003000	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
595495003001	uncharacterized protein, YhcH/YjgK/YiaL family; Region: TIGR00022
595495003002	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
595495003003	Transcriptional regulator [Transcription]; Region: IclR; COG1414
595495003004	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
595495003005	Bacterial transcriptional regulator; Region: IclR; pfam01614
595495003006	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
595495003007	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
595495003008	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
595495003009	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
595495003010	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495003011	homodimer interface [polypeptide binding]; other site
595495003012	catalytic residue [active]
595495003013	alpha-amylase; Reviewed; Region: malS; PRK09505
595495003014	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
595495003015	active site
595495003016	catalytic site [active]
595495003017	hypothetical protein; Provisional; Region: PRK10356
595495003018	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
595495003019	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
595495003020	putative dimerization interface [polypeptide binding]; other site
595495003021	Transcriptional regulators [Transcription]; Region: PurR; COG1609
595495003022	putative ligand binding site [chemical binding]; other site
595495003023	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495003024	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
595495003025	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495003026	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
595495003027	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
595495003028	TM-ABC transporter signature motif; other site
595495003029	xylose transporter ATP-binding subunit; Provisional; Region: PRK13549
595495003030	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
595495003031	Walker A/P-loop; other site
595495003032	ATP binding site [chemical binding]; other site
595495003033	Q-loop/lid; other site
595495003034	ABC transporter signature motif; other site
595495003035	Walker B; other site
595495003036	D-loop; other site
595495003037	H-loop/switch region; other site
595495003038	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
595495003039	D-xylose transporter subunit XylF; Provisional; Region: xylF; PRK10355
595495003040	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
595495003041	putative ligand binding site [chemical binding]; other site
595495003042	xylose isomerase; Provisional; Region: PRK05474
595495003043	xylose isomerase; Region: xylose_isom_A; TIGR02630
595495003044	xylulokinase; Provisional; Region: PRK15027
595495003045	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
595495003046	N- and C-terminal domain interface [polypeptide binding]; other site
595495003047	active site
595495003048	MgATP binding site [chemical binding]; other site
595495003049	catalytic site [active]
595495003050	metal binding site [ion binding]; metal-binding site
595495003051	xylulose binding site [chemical binding]; other site
595495003052	homodimer interface [polypeptide binding]; other site
595495003053	hypothetical protein; Provisional; Region: PRK11403
595495003054	yiaA/B two helix domain; Region: YiaAB; pfam05360
595495003055	hypothetical protein; Provisional; Region: PRK11383
595495003056	yiaA/B two helix domain; Region: YiaAB; pfam05360
595495003057	yiaA/B two helix domain; Region: YiaAB; pfam05360
595495003058	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
595495003059	Acyltransferase family; Region: Acyl_transf_3; pfam01757
595495003060	YsaB-like lipoprotein; Region: YsaB; pfam13983
595495003061	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
595495003062	dimer interface [polypeptide binding]; other site
595495003063	motif 1; other site
595495003064	active site
595495003065	motif 2; other site
595495003066	motif 3; other site
595495003067	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
595495003068	DALR anticodon binding domain; Region: DALR_1; pfam05746
595495003069	anticodon binding site; other site
595495003070	tRNA binding surface [nucleotide binding]; other site
595495003071	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
595495003072	Helix-turn-helix domain; Region: HTH_28; pfam13518
595495003073	Helix-turn-helix domain; Region: HTH_28; pfam13518
595495003074	putative transposase OrfB; Reviewed; Region: PHA02517
595495003075	HTH-like domain; Region: HTH_21; pfam13276
595495003076	Integrase core domain; Region: rve; pfam00665
595495003077	Integrase core domain; Region: rve_2; pfam13333
595495003078	small toxic polypeptide; Provisional; Region: PRK09759
595495003079	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
595495003080	DNA-binding site [nucleotide binding]; DNA binding site
595495003081	RNA-binding motif; other site
595495003082	Predicted transcriptional regulator [Transcription]; Region: COG2944
595495003083	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
595495003084	non-specific DNA binding site [nucleotide binding]; other site
595495003085	salt bridge; other site
595495003086	sequence-specific DNA binding site [nucleotide binding]; other site
595495003087	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
595495003088	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
595495003089	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
595495003090	dimerization interface [polypeptide binding]; other site
595495003091	ligand binding site [chemical binding]; other site
595495003092	NADP binding site [chemical binding]; other site
595495003093	catalytic site [active]
595495003094	putative outer membrane lipoprotein; Provisional; Region: PRK10510
595495003095	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
595495003096	ligand binding site [chemical binding]; other site
595495003097	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
595495003098	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
595495003099	molybdopterin cofactor binding site [chemical binding]; other site
595495003100	substrate binding site [chemical binding]; other site
595495003101	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
595495003102	molybdopterin cofactor binding site; other site
595495003103	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
595495003104	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
595495003105	Coenzyme A binding pocket [chemical binding]; other site
595495003106	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
595495003107	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
595495003108	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
595495003109	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495003110	putative substrate translocation pore; other site
595495003111	long polar fimbrial protein LpfA; Provisional; Region: PRK15209
595495003112	long polar fimbrial chaperone LpfB; Provisional; Region: PRK15208
595495003113	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
595495003114	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
595495003115	long polar fimbrial outer membrane usher protein LpfC; Provisional; Region: PRK15207
595495003116	PapC N-terminal domain; Region: PapC_N; pfam13954
595495003117	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
595495003118	PapC C-terminal domain; Region: PapC_C; pfam13953
595495003119	long polar fimbrial protein LpfD; Provisional; Region: PRK15206
595495003120	long polar fimbrial protein LpfE; Provisional; Region: PRK15205
595495003121	phosphoethanolamine transferase; Provisional; Region: PRK11560
595495003122	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
595495003123	Sulfatase; Region: Sulfatase; pfam00884
595495003124	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
595495003125	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
595495003126	peptide binding site [polypeptide binding]; other site
595495003127	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
595495003128	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495003129	dimer interface [polypeptide binding]; other site
595495003130	conserved gate region; other site
595495003131	putative PBP binding loops; other site
595495003132	ABC-ATPase subunit interface; other site
595495003133	dipeptide transporter; Provisional; Region: PRK10913
595495003134	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
595495003135	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495003136	dimer interface [polypeptide binding]; other site
595495003137	conserved gate region; other site
595495003138	putative PBP binding loops; other site
595495003139	ABC-ATPase subunit interface; other site
595495003140	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
595495003141	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
595495003142	Walker A/P-loop; other site
595495003143	ATP binding site [chemical binding]; other site
595495003144	Q-loop/lid; other site
595495003145	ABC transporter signature motif; other site
595495003146	Walker B; other site
595495003147	D-loop; other site
595495003148	H-loop/switch region; other site
595495003149	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
595495003150	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
595495003151	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
595495003152	Walker A/P-loop; other site
595495003153	ATP binding site [chemical binding]; other site
595495003154	Q-loop/lid; other site
595495003155	ABC transporter signature motif; other site
595495003156	Walker B; other site
595495003157	D-loop; other site
595495003158	H-loop/switch region; other site
595495003159	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
595495003160	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
595495003161	serine transporter; Region: stp; TIGR00814
595495003162	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
595495003163	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
595495003164	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
595495003165	Protein of unknown function (DUF3260); Region: DUF3260; pfam11658
595495003166	celllulose biosynthesis operon protein BcsF/YhjT; Region: cellullose_BcsF; TIGR03493
595495003167	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
595495003168	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
595495003169	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
595495003170	cell division protein; Provisional; Region: PRK10037
595495003171	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
595495003172	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
595495003173	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
595495003174	DXD motif; other site
595495003175	PilZ domain; Region: PilZ; pfam07238
595495003176	cellulose synthase regulator protein; Provisional; Region: PRK11114
595495003177	endo-1,4-D-glucanase; Provisional; Region: PRK11097
595495003178	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
595495003179	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
595495003180	binding surface
595495003181	TPR motif; other site
595495003182	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
595495003183	binding surface
595495003184	TPR motif; other site
595495003185	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
595495003186	putative diguanylate cyclase; Provisional; Region: PRK13561
595495003187	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
595495003188	metal binding site [ion binding]; metal-binding site
595495003189	active site
595495003190	I-site; other site
595495003191	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
595495003192	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
595495003193	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
595495003194	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
595495003195	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
595495003196	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
595495003197	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
595495003198	substrate binding site [chemical binding]; other site
595495003199	ATP binding site [chemical binding]; other site
595495003200	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
595495003201	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
595495003202	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
595495003203	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495003204	metabolite-proton symporter; Region: 2A0106; TIGR00883
595495003205	putative substrate translocation pore; other site
595495003206	inner membrane protein YhjD; Region: TIGR00766
595495003207	Transcriptional regulator [Transcription]; Region: LysR; COG0583
595495003208	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495003209	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
595495003210	putative effector binding pocket; other site
595495003211	putative dimerization interface [polypeptide binding]; other site
595495003212	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
595495003213	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
595495003214	DNA binding residues [nucleotide binding]
595495003215	dimerization interface [polypeptide binding]; other site
595495003216	trehalase; Provisional; Region: treF; PRK13270
595495003217	Trehalase; Region: Trehalase; pfam01204
595495003218	Haem-binding domain; Region: Haem_bd; pfam14376
595495003219	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
595495003220	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
595495003221	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495003222	catalytic residue [active]
595495003223	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
595495003224	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495003225	transcriptional regulator YdeO; Provisional; Region: PRK09940
595495003226	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495003227	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
595495003228	Protein export membrane protein; Region: SecD_SecF; cl14618
595495003229	multidrug efflux system protein MdtE; Provisional; Region: PRK09859
595495003230	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
595495003231	HlyD family secretion protein; Region: HlyD_3; pfam13437
595495003232	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
595495003233	pyruvate kinase; Provisional; Region: PRK05826
595495003234	acid-resistance membrane protein; Provisional; Region: PRK10209
595495003235	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
595495003236	acid-resistance protein; Provisional; Region: PRK10208
595495003237	acid-resistance protein; Provisional; Region: hdeB; PRK11566
595495003238	putative Mg(2+) transport ATPase; Provisional; Region: PRK09977
595495003239	MgtC family; Region: MgtC; pfam02308
595495003240	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
595495003241	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
595495003242	DNA binding residues [nucleotide binding]
595495003243	dimerization interface [polypeptide binding]; other site
595495003244	outer membrane lipoprotein, Slp family; Region: slp; TIGR00752
595495003245	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495003246	Predicted permeases [General function prediction only]; Region: COG0701
595495003247	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
595495003248	dimerization interface [polypeptide binding]; other site
595495003249	putative DNA binding site [nucleotide binding]; other site
595495003250	putative Zn2+ binding site [ion binding]; other site
595495003251	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
595495003252	ArsC family; Region: ArsC; pfam03960
595495003253	catalytic residues [active]
595495003254	arsenical pump membrane protein; Provisional; Region: PRK15445
595495003255	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
595495003256	transmembrane helices; other site
595495003257	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
595495003258	dimerization interface [polypeptide binding]; other site
595495003259	putative DNA binding site [nucleotide binding]; other site
595495003260	putative Zn2+ binding site [ion binding]; other site
595495003261	glutathione reductase; Validated; Region: PRK06116
595495003262	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
595495003263	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
595495003264	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
595495003265	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
595495003266	oligopeptidase A; Provisional; Region: PRK10911
595495003267	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
595495003268	active site
595495003269	Zn binding site [ion binding]; other site
595495003270	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495003271	S-adenosylmethionine binding site [chemical binding]; other site
595495003272	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
595495003273	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495003274	putative substrate translocation pore; other site
595495003275	POT family; Region: PTR2; pfam00854
595495003276	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
595495003277	Ligand Binding Site [chemical binding]; other site
595495003278	universal stress protein UspB; Provisional; Region: PRK04960
595495003279	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
595495003280	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
595495003281	Predicted flavoproteins [General function prediction only]; Region: COG2081
595495003282	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
595495003283	Protein of unknown function (DUF2776); Region: DUF2776; pfam10951
595495003284	Domain of unknown function (DUF4049); Region: DUF4049; pfam13258
595495003285	Domain of unknown function (DUF4049); Region: DUF4049; pfam13258
595495003286	HlyD family secretion protein; Region: HlyD; pfam00529
595495003287	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
595495003288	HlyD family secretion protein; Region: HlyD_3; pfam13437
595495003289	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
595495003290	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
595495003291	Walker A/P-loop; other site
595495003292	ATP binding site [chemical binding]; other site
595495003293	Q-loop/lid; other site
595495003294	ABC transporter signature motif; other site
595495003295	Walker B; other site
595495003296	D-loop; other site
595495003297	H-loop/switch region; other site
595495003298	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
595495003299	Walker A/P-loop; other site
595495003300	ATP binding site [chemical binding]; other site
595495003301	Q-loop/lid; other site
595495003302	ABC transporter signature motif; other site
595495003303	Walker B; other site
595495003304	D-loop; other site
595495003305	H-loop/switch region; other site
595495003306	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
595495003307	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
595495003308	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
595495003309	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
595495003310	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
595495003311	HicB family; Region: HicB; pfam05534
595495003312	nickel responsive regulator; Provisional; Region: PRK02967
595495003313	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
595495003314	nickel transporter ATP-binding protein NikE; Provisional; Region: nikE; PRK10419
595495003315	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
595495003316	Walker A/P-loop; other site
595495003317	ATP binding site [chemical binding]; other site
595495003318	Q-loop/lid; other site
595495003319	ABC transporter signature motif; other site
595495003320	Walker B; other site
595495003321	D-loop; other site
595495003322	H-loop/switch region; other site
595495003323	nickel transporter ATP-binding protein NikD; Provisional; Region: nikD; PRK10418
595495003324	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
595495003325	Walker A/P-loop; other site
595495003326	ATP binding site [chemical binding]; other site
595495003327	Q-loop/lid; other site
595495003328	ABC transporter signature motif; other site
595495003329	Walker B; other site
595495003330	D-loop; other site
595495003331	H-loop/switch region; other site
595495003332	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
595495003333	nickel transporter permease NikC; Provisional; Region: nikC; PRK10417
595495003334	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495003335	dimer interface [polypeptide binding]; other site
595495003336	conserved gate region; other site
595495003337	putative PBP binding loops; other site
595495003338	ABC-ATPase subunit interface; other site
595495003339	nickel transporter permease NikB; Provisional; Region: PRK10352
595495003340	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495003341	dimer interface [polypeptide binding]; other site
595495003342	conserved gate region; other site
595495003343	putative PBP binding loops; other site
595495003344	ABC-ATPase subunit interface; other site
595495003345	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
595495003346	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
595495003347	substrate binding site [chemical binding]; other site
595495003348	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
595495003349	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
595495003350	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
595495003351	Domain of unknown function DUF20; Region: UPF0118; pfam01594
595495003352	major facilitator superfamily transporter; Provisional; Region: PRK05122
595495003353	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495003354	putative substrate translocation pore; other site
595495003355	hypothetical protein; Provisional; Region: PRK11615
595495003356	hypothetical protein; Provisional; Region: PRK11212
595495003357	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
595495003358	CPxP  motif; other site
595495003359	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
595495003360	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
595495003361	metal-binding site [ion binding]
595495003362	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
595495003363	Predicted membrane protein [Function unknown]; Region: COG3714
595495003364	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
595495003365	hypothetical protein; Provisional; Region: PRK10910
595495003366	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
595495003367	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495003368	S-adenosylmethionine binding site [chemical binding]; other site
595495003369	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
595495003370	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
595495003371	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
595495003372	P loop; other site
595495003373	GTP binding site [chemical binding]; other site
595495003374	cell division protein FtsE; Provisional; Region: PRK10908
595495003375	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495003376	Walker A/P-loop; other site
595495003377	ATP binding site [chemical binding]; other site
595495003378	Q-loop/lid; other site
595495003379	ABC transporter signature motif; other site
595495003380	Walker B; other site
595495003381	D-loop; other site
595495003382	H-loop/switch region; other site
595495003383	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
595495003384	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
595495003385	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
595495003386	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
595495003387	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
595495003388	DNA binding residues [nucleotide binding]
595495003389	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
595495003390	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
595495003391	dimerization interface [polypeptide binding]; other site
595495003392	ligand binding site [chemical binding]; other site
595495003393	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
595495003394	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
595495003395	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
595495003396	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
595495003397	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
595495003398	dimerization interface [polypeptide binding]; other site
595495003399	ligand binding site [chemical binding]; other site
595495003400	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
595495003401	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
595495003402	TM-ABC transporter signature motif; other site
595495003403	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
595495003404	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
595495003405	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
595495003406	TM-ABC transporter signature motif; other site
595495003407	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
595495003408	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
595495003409	Walker A/P-loop; other site
595495003410	ATP binding site [chemical binding]; other site
595495003411	Q-loop/lid; other site
595495003412	ABC transporter signature motif; other site
595495003413	Walker B; other site
595495003414	D-loop; other site
595495003415	H-loop/switch region; other site
595495003416	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
595495003417	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
595495003418	Walker A/P-loop; other site
595495003419	ATP binding site [chemical binding]; other site
595495003420	Q-loop/lid; other site
595495003421	ABC transporter signature motif; other site
595495003422	Walker B; other site
595495003423	D-loop; other site
595495003424	H-loop/switch region; other site
595495003425	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
595495003426	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
595495003427	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
595495003428	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495003429	dimer interface [polypeptide binding]; other site
595495003430	conserved gate region; other site
595495003431	putative PBP binding loops; other site
595495003432	ABC-ATPase subunit interface; other site
595495003433	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
595495003434	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495003435	dimer interface [polypeptide binding]; other site
595495003436	conserved gate region; other site
595495003437	putative PBP binding loops; other site
595495003438	ABC-ATPase subunit interface; other site
595495003439	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
595495003440	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
595495003441	Walker A/P-loop; other site
595495003442	ATP binding site [chemical binding]; other site
595495003443	Q-loop/lid; other site
595495003444	ABC transporter signature motif; other site
595495003445	Walker B; other site
595495003446	D-loop; other site
595495003447	H-loop/switch region; other site
595495003448	TOBE domain; Region: TOBE_2; pfam08402
595495003449	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
595495003450	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
595495003451	putative active site [active]
595495003452	catalytic site [active]
595495003453	putative metal binding site [ion binding]; other site
595495003454	hypothetical protein; Provisional; Region: PRK10350
595495003455	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
595495003456	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
595495003457	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
595495003458	putative acetyltransferase YhhY; Provisional; Region: PRK10140
595495003459	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
595495003460	Coenzyme A binding pocket [chemical binding]; other site
595495003461	putative oxidoreductase; Provisional; Region: PRK10206
595495003462	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
595495003463	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
595495003464	Pirin-related protein [General function prediction only]; Region: COG1741
595495003465	Pirin; Region: Pirin; pfam02678
595495003466	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
595495003467	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
595495003468	DNA binding site [nucleotide binding]
595495003469	domain linker motif; other site
595495003470	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
595495003471	putative ligand binding site [chemical binding]; other site
595495003472	putative dimerization interface [polypeptide binding]; other site
595495003473	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
595495003474	Shikimate kinase; Region: SKI; pfam01202
595495003475	low affinity gluconate transporter; Provisional; Region: PRK10472
595495003476	gluconate transporter; Region: gntP; TIGR00791
595495003477	putative antibiotic transporter; Provisional; Region: PRK10739
595495003478	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
595495003479	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
595495003480	glycogen branching enzyme; Provisional; Region: PRK05402
595495003481	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
595495003482	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
595495003483	active site
595495003484	catalytic site [active]
595495003485	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
595495003486	glycogen debranching enzyme; Provisional; Region: PRK03705
595495003487	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
595495003488	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
595495003489	active site
595495003490	catalytic site [active]
595495003491	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
595495003492	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
595495003493	ligand binding site; other site
595495003494	oligomer interface; other site
595495003495	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
595495003496	sulfate 1 binding site; other site
595495003497	glycogen synthase; Provisional; Region: glgA; PRK00654
595495003498	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
595495003499	ADP-binding pocket [chemical binding]; other site
595495003500	homodimer interface [polypeptide binding]; other site
595495003501	glycogen phosphorylase; Provisional; Region: PRK14986
595495003502	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
595495003503	homodimer interface [polypeptide binding]; other site
595495003504	active site pocket [active]
595495003505	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
595495003506	hypothetical protein; Provisional; Region: PRK09781; cl08057
595495003507	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495003508	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
595495003509	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
595495003510	active site residue [active]
595495003511	intramembrane serine protease GlpG; Provisional; Region: PRK10907
595495003512	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
595495003513	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
595495003514	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
595495003515	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
595495003516	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
595495003517	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
595495003518	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
595495003519	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495003520	Walker A motif; other site
595495003521	ATP binding site [chemical binding]; other site
595495003522	Walker B motif; other site
595495003523	arginine finger; other site
595495003524	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
595495003525	hypothetical protein; Reviewed; Region: PRK09588
595495003526	RNA 3'-terminal-phosphate cyclase; Provisional; Region: PRK04204
595495003527	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288
595495003528	putative active site [active]
595495003529	transcriptional regulator MalT; Provisional; Region: PRK04841
595495003530	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
595495003531	DNA binding residues [nucleotide binding]
595495003532	maltodextrin phosphorylase; Provisional; Region: PRK14985
595495003533	maltodextrin phosphorylase; Provisional; Region: PRK14985
595495003534	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
595495003535	active site pocket [active]
595495003536	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
595495003537	4-alpha-glucanotransferase; Region: malQ; TIGR00217
595495003538	high-affinity gluconate transporter; Provisional; Region: PRK14984
595495003539	gluconate transporter; Region: gntP; TIGR00791
595495003540	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
595495003541	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
595495003542	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
595495003543	DNA utilization protein GntX; Provisional; Region: PRK11595
595495003544	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
595495003545	active site
595495003546	carboxylesterase BioH; Provisional; Region: PRK10349
595495003547	methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657
595495003548	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
595495003549	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
595495003550	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
595495003551	G1 box; other site
595495003552	GTP/Mg2+ binding site [chemical binding]; other site
595495003553	Switch I region; other site
595495003554	G2 box; other site
595495003555	G3 box; other site
595495003556	Switch II region; other site
595495003557	G4 box; other site
595495003558	G5 box; other site
595495003559	Nucleoside recognition; Region: Gate; pfam07670
595495003560	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
595495003561	Nucleoside recognition; Region: Gate; pfam07670
595495003562	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
595495003563	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
595495003564	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
595495003565	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
595495003566	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
595495003567	RNA binding site [nucleotide binding]; other site
595495003568	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
595495003569	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
595495003570	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
595495003571	osmolarity response regulator; Provisional; Region: ompR; PRK09468
595495003572	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495003573	active site
595495003574	phosphorylation site [posttranslational modification]
595495003575	intermolecular recognition site; other site
595495003576	dimerization interface [polypeptide binding]; other site
595495003577	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
595495003578	DNA binding site [nucleotide binding]
595495003579	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
595495003580	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
595495003581	dimerization interface [polypeptide binding]; other site
595495003582	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
595495003583	dimer interface [polypeptide binding]; other site
595495003584	phosphorylation site [posttranslational modification]
595495003585	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495003586	ATP binding site [chemical binding]; other site
595495003587	G-X-G motif; other site
595495003588	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
595495003589	non-specific DNA binding site [nucleotide binding]; other site
595495003590	salt bridge; other site
595495003591	sequence-specific DNA binding site [nucleotide binding]; other site
595495003592	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
595495003593	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
595495003594	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
595495003595	active site
595495003596	substrate-binding site [chemical binding]; other site
595495003597	metal-binding site [ion binding]
595495003598	ATP binding site [chemical binding]; other site
595495003599	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
595495003600	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
595495003601	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
595495003602	dimerization interface [polypeptide binding]; other site
595495003603	domain crossover interface; other site
595495003604	redox-dependent activation switch; other site
595495003605	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
595495003606	RNA binding surface [nucleotide binding]; other site
595495003607	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
595495003608	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495003609	motif II; other site
595495003610	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
595495003611	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
595495003612	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
595495003613	ADP-ribose binding site [chemical binding]; other site
595495003614	dimer interface [polypeptide binding]; other site
595495003615	active site
595495003616	nudix motif; other site
595495003617	metal binding site [ion binding]; metal-binding site
595495003618	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
595495003619	Transglycosylase; Region: Transgly; pfam00912
595495003620	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
595495003621	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
595495003622	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
595495003623	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
595495003624	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
595495003625	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
595495003626	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
595495003627	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
595495003628	shikimate kinase; Reviewed; Region: aroK; PRK00131
595495003629	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
595495003630	ADP binding site [chemical binding]; other site
595495003631	magnesium binding site [ion binding]; other site
595495003632	putative shikimate binding site; other site
595495003633	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
595495003634	active site
595495003635	dimer interface [polypeptide binding]; other site
595495003636	metal binding site [ion binding]; metal-binding site
595495003637	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DamX; COG3266
595495003638	cell division protein DamX; Validated; Region: PRK10905
595495003639	DNA adenine methylase; Provisional; Region: PRK10904
595495003640	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
595495003641	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
595495003642	substrate binding site [chemical binding]; other site
595495003643	hexamer interface [polypeptide binding]; other site
595495003644	metal binding site [ion binding]; metal-binding site
595495003645	phosphoglycolate phosphatase; Provisional; Region: PRK13222
595495003646	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495003647	motif II; other site
595495003648	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
595495003649	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
595495003650	active site
595495003651	HIGH motif; other site
595495003652	dimer interface [polypeptide binding]; other site
595495003653	KMSKS motif; other site
595495003654	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
595495003655	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme yhfX; Region: PLPDE_III_yhfX_like; cd06811
595495003656	dimer interface [polypeptide binding]; other site
595495003657	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
595495003658	active site
595495003659	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
595495003660	substrate binding site [chemical binding]; other site
595495003661	catalytic residue [active]
595495003662	putative mutase; Provisional; Region: PRK12383
595495003663	Phosphopentomutase [Carbohydrate transport and metabolism]; Region: DeoB; COG1015
595495003664	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
595495003665	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
595495003666	active site
595495003667	substrate binding pocket [chemical binding]; other site
595495003668	homodimer interaction site [polypeptide binding]; other site
595495003669	Protein of unknown function DUF2620; Region: DUF2620; pfam10941
595495003670	Protein of unknown function; Region: YhfT; pfam10797
595495003671	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
595495003672	DNA topoisomerase III, bacteria and conjugative plasmid; Region: topB; TIGR01056
595495003673	DNA-binding transcriptional regulator FrlR; Provisional; Region: PRK11402
595495003674	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
595495003675	DNA-binding site [nucleotide binding]; DNA binding site
595495003676	UTRA domain; Region: UTRA; pfam07702
595495003677	Fructoselysine kinase-like.  Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the...; Region: Fructoselysine_kinase_like; cd01940
595495003678	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
595495003679	substrate binding site [chemical binding]; other site
595495003680	ATP binding site [chemical binding]; other site
595495003681	fructoselysine 3-epimerase; Provisional; Region: PRK09856
595495003682	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
595495003683	AP (apurinic/apyrimidinic) site pocket; other site
595495003684	DNA interaction; other site
595495003685	Metal-binding active site; metal-binding site
595495003686	fructoselysine-6-P-deglycase; Provisional; Region: frlB; PRK11382
595495003687	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
595495003688	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
595495003689	dimer interface [polypeptide binding]; other site
595495003690	active site
595495003691	putative fructoselysine transporter; Provisional; Region: frlA; PRK11357
595495003692	hypothetical protein; Provisional; Region: PHA02764
595495003693	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
595495003694	siroheme synthase; Provisional; Region: cysG; PRK10637
595495003695	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
595495003696	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
595495003697	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
595495003698	active site
595495003699	SAM binding site [chemical binding]; other site
595495003700	homodimer interface [polypeptide binding]; other site
595495003701	nitrite transporter NirC; Provisional; Region: PRK11562
595495003702	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
595495003703	nitrite reductase subunit NirD; Provisional; Region: PRK14989
595495003704	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
595495003705	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
595495003706	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
595495003707	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
595495003708	putative transporter; Provisional; Region: PRK03699
595495003709	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495003710	putative substrate translocation pore; other site
595495003711	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
595495003712	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
595495003713	substrate binding site [chemical binding]; other site
595495003714	hypothetical protein; Provisional; Region: PRK10204
595495003715	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
595495003716	cell filamentation protein Fic; Provisional; Region: PRK10347
595495003717	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
595495003718	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
595495003719	glutamine binding [chemical binding]; other site
595495003720	catalytic triad [active]
595495003721	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
595495003722	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
595495003723	inhibitor-cofactor binding pocket; inhibition site
595495003724	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495003725	catalytic residue [active]
595495003726	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
595495003727	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
595495003728	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
595495003729	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
595495003730	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
595495003731	ligand binding site [chemical binding]; other site
595495003732	flexible hinge region; other site
595495003733	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
595495003734	putative switch regulator; other site
595495003735	non-specific DNA interactions [nucleotide binding]; other site
595495003736	DNA binding site [nucleotide binding]
595495003737	sequence specific DNA binding site [nucleotide binding]; other site
595495003738	putative cAMP binding site [chemical binding]; other site
595495003739	hypothetical protein; Provisional; Region: PRK10738
595495003740	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
595495003741	active site
595495003742	hypothetical protein; Provisional; Region: PRK04966
595495003743	putative hydrolase; Provisional; Region: PRK10985
595495003744	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
595495003745	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495003746	Walker A/P-loop; other site
595495003747	ATP binding site [chemical binding]; other site
595495003748	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
595495003749	ABC transporter signature motif; other site
595495003750	Walker B; other site
595495003751	D-loop; other site
595495003752	ABC transporter; Region: ABC_tran_2; pfam12848
595495003753	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
595495003754	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
595495003755	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
595495003756	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
595495003757	TrkA-N domain; Region: TrkA_N; pfam02254
595495003758	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
595495003759	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
595495003760	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
595495003761	phi X174 lysis protein; Provisional; Region: PRK02793
595495003762	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
595495003763	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
595495003764	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
595495003765	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
595495003766	YheO-like PAS domain; Region: PAS_6; pfam08348
595495003767	HTH domain; Region: HTH_22; pfam13309
595495003768	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
595495003769	sulfur relay protein TusC; Validated; Region: PRK00211
595495003770	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
595495003771	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
595495003772	S17 interaction site [polypeptide binding]; other site
595495003773	S8 interaction site; other site
595495003774	16S rRNA interaction site [nucleotide binding]; other site
595495003775	streptomycin interaction site [chemical binding]; other site
595495003776	23S rRNA interaction site [nucleotide binding]; other site
595495003777	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
595495003778	30S ribosomal protein S7; Validated; Region: PRK05302
595495003779	elongation factor G; Reviewed; Region: PRK00007
595495003780	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
595495003781	G1 box; other site
595495003782	putative GEF interaction site [polypeptide binding]; other site
595495003783	GTP/Mg2+ binding site [chemical binding]; other site
595495003784	Switch I region; other site
595495003785	G2 box; other site
595495003786	G3 box; other site
595495003787	Switch II region; other site
595495003788	G4 box; other site
595495003789	G5 box; other site
595495003790	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
595495003791	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
595495003792	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
595495003793	elongation factor Tu; Reviewed; Region: PRK00049
595495003794	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
595495003795	G1 box; other site
595495003796	GEF interaction site [polypeptide binding]; other site
595495003797	GTP/Mg2+ binding site [chemical binding]; other site
595495003798	Switch I region; other site
595495003799	G2 box; other site
595495003800	G3 box; other site
595495003801	Switch II region; other site
595495003802	G4 box; other site
595495003803	G5 box; other site
595495003804	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
595495003805	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
595495003806	Antibiotic Binding Site [chemical binding]; other site
595495003807	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
595495003808	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
595495003809	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
595495003810	heme binding site [chemical binding]; other site
595495003811	ferroxidase pore; other site
595495003812	ferroxidase diiron center [ion binding]; other site
595495003813	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
595495003814	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
595495003815	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
595495003816	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
595495003817	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
595495003818	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
595495003819	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
595495003820	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
595495003821	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
595495003822	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
595495003823	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
595495003824	protein-rRNA interface [nucleotide binding]; other site
595495003825	putative translocon binding site; other site
595495003826	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
595495003827	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
595495003828	G-X-X-G motif; other site
595495003829	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
595495003830	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
595495003831	23S rRNA interface [nucleotide binding]; other site
595495003832	5S rRNA interface [nucleotide binding]; other site
595495003833	putative antibiotic binding site [chemical binding]; other site
595495003834	L25 interface [polypeptide binding]; other site
595495003835	L27 interface [polypeptide binding]; other site
595495003836	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
595495003837	23S rRNA interface [nucleotide binding]; other site
595495003838	putative translocon interaction site; other site
595495003839	signal recognition particle (SRP54) interaction site; other site
595495003840	L23 interface [polypeptide binding]; other site
595495003841	trigger factor interaction site; other site
595495003842	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
595495003843	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
595495003844	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
595495003845	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
595495003846	RNA binding site [nucleotide binding]; other site
595495003847	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
595495003848	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
595495003849	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
595495003850	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
595495003851	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
595495003852	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
595495003853	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
595495003854	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
595495003855	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
595495003856	23S rRNA interface [nucleotide binding]; other site
595495003857	5S rRNA interface [nucleotide binding]; other site
595495003858	L27 interface [polypeptide binding]; other site
595495003859	L5 interface [polypeptide binding]; other site
595495003860	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
595495003861	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
595495003862	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
595495003863	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
595495003864	23S rRNA binding site [nucleotide binding]; other site
595495003865	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
595495003866	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
595495003867	SecY translocase; Region: SecY; pfam00344
595495003868	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
595495003869	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
595495003870	30S ribosomal protein S13; Region: bact_S13; TIGR03631
595495003871	30S ribosomal protein S11; Validated; Region: PRK05309
595495003872	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
595495003873	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
595495003874	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
595495003875	RNA binding surface [nucleotide binding]; other site
595495003876	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
595495003877	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
595495003878	alphaNTD homodimer interface [polypeptide binding]; other site
595495003879	alphaNTD - beta interaction site [polypeptide binding]; other site
595495003880	alphaNTD - beta' interaction site [polypeptide binding]; other site
595495003881	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
595495003882	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
595495003883	hypothetical protein; Provisional; Region: PRK10203
595495003884	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
595495003885	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
595495003886	DNA binding residues [nucleotide binding]
595495003887	dimer interface [polypeptide binding]; other site
595495003888	metal binding site [ion binding]; metal-binding site
595495003889	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
595495003890	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
595495003891	Large-conductance mechanosensitive channel, MscL; Region: MscL; pfam01741
595495003892	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
595495003893	TrkA-N domain; Region: TrkA_N; pfam02254
595495003894	TrkA-C domain; Region: TrkA_C; pfam02080
595495003895	TrkA-N domain; Region: TrkA_N; pfam02254
595495003896	TrkA-C domain; Region: TrkA_C; pfam02080
595495003897	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
595495003898	putative RNA binding site [nucleotide binding]; other site
595495003899	16S rRNA methyltransferase B; Provisional; Region: PRK10901
595495003900	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495003901	S-adenosylmethionine binding site [chemical binding]; other site
595495003902	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
595495003903	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
595495003904	putative active site [active]
595495003905	substrate binding site [chemical binding]; other site
595495003906	putative cosubstrate binding site; other site
595495003907	catalytic site [active]
595495003908	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
595495003909	substrate binding site [chemical binding]; other site
595495003910	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
595495003911	active site
595495003912	catalytic residues [active]
595495003913	metal binding site [ion binding]; metal-binding site
595495003914	hypothetical protein; Provisional; Region: PRK10736
595495003915	DNA protecting protein DprA; Region: dprA; TIGR00732
595495003916	hypothetical protein; Validated; Region: PRK03430
595495003917	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
595495003918	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
595495003919	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
595495003920	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
595495003921	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
595495003922	shikimate 5-dehydrogenase; Region: aroE; TIGR00507
595495003923	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
595495003924	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
595495003925	shikimate binding site; other site
595495003926	NAD(P) binding site [chemical binding]; other site
595495003927	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
595495003928	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
595495003929	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
595495003930	trimer interface [polypeptide binding]; other site
595495003931	putative metal binding site [ion binding]; other site
595495003932	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
595495003933	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
595495003934	Walker A/P-loop; other site
595495003935	ATP binding site [chemical binding]; other site
595495003936	Q-loop/lid; other site
595495003937	ABC transporter signature motif; other site
595495003938	Walker B; other site
595495003939	D-loop; other site
595495003940	H-loop/switch region; other site
595495003941	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
595495003942	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495003943	dimer interface [polypeptide binding]; other site
595495003944	conserved gate region; other site
595495003945	putative PBP binding loops; other site
595495003946	ABC-ATPase subunit interface; other site
595495003947	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: BatB; COG4597
595495003948	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495003949	conserved gate region; other site
595495003950	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495003951	dimer interface [polypeptide binding]; other site
595495003952	conserved gate region; other site
595495003953	putative PBP binding loops; other site
595495003954	ABC-ATPase subunit interface; other site
595495003955	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
595495003956	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
595495003957	substrate binding pocket [chemical binding]; other site
595495003958	membrane-bound complex binding site; other site
595495003959	hinge residues; other site
595495003960	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
595495003961	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
595495003962	Protein export membrane protein; Region: SecD_SecF; cl14618
595495003963	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
595495003964	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
595495003965	HlyD family secretion protein; Region: HlyD_3; pfam13437
595495003966	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
595495003967	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
595495003968	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
595495003969	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
595495003970	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
595495003971	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495003972	DNA methylase; Region: N6_N4_Mtase; pfam01555
595495003973	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
595495003974	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
595495003975	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
595495003976	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
595495003977	FMN binding site [chemical binding]; other site
595495003978	active site
595495003979	catalytic residues [active]
595495003980	substrate binding site [chemical binding]; other site
595495003981	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
595495003982	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
595495003983	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
595495003984	Na binding site [ion binding]; other site
595495003985	hypothetical protein; Provisional; Region: PRK10633
595495003986	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
595495003987	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
595495003988	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
595495003989	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
595495003990	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
595495003991	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
595495003992	carboxyltransferase (CT) interaction site; other site
595495003993	biotinylation site [posttranslational modification]; other site
595495003994	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
595495003995	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
595495003996	NADP binding site [chemical binding]; other site
595495003997	dimer interface [polypeptide binding]; other site
595495003998	regulatory protein CsrD; Provisional; Region: PRK11059
595495003999	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
595495004000	metal binding site [ion binding]; metal-binding site
595495004001	active site
595495004002	I-site; other site
595495004003	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
595495004004	rod shape-determining protein MreB; Provisional; Region: PRK13927
595495004005	MreB and similar proteins; Region: MreB_like; cd10225
595495004006	nucleotide binding site [chemical binding]; other site
595495004007	Mg binding site [ion binding]; other site
595495004008	putative protofilament interaction site [polypeptide binding]; other site
595495004009	RodZ interaction site [polypeptide binding]; other site
595495004010	rod shape-determining protein MreC; Region: mreC; TIGR00219
595495004011	rod shape-determining protein MreC; Region: MreC; pfam04085
595495004012	rod shape-determining protein MreD; Provisional; Region: PRK11060
595495004013	Maf-like protein; Region: Maf; pfam02545
595495004014	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
595495004015	active site
595495004016	dimer interface [polypeptide binding]; other site
595495004017	ribonuclease G; Provisional; Region: PRK11712
595495004018	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
595495004019	homodimer interface [polypeptide binding]; other site
595495004020	oligonucleotide binding site [chemical binding]; other site
595495004021	hypothetical protein; Provisional; Region: PRK10899
595495004022	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
595495004023	protease TldD; Provisional; Region: tldD; PRK10735
595495004024	transcriptional regulator; Provisional; Region: PRK10632
595495004025	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495004026	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
595495004027	putative effector binding pocket; other site
595495004028	dimerization interface [polypeptide binding]; other site
595495004029	efflux system membrane protein; Provisional; Region: PRK11594
595495004030	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
595495004031	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
595495004032	HlyD family secretion protein; Region: HlyD_3; pfam13437
595495004033	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
595495004034	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
595495004035	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
595495004036	RNAase interaction site [polypeptide binding]; other site
595495004037	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
595495004038	arginine repressor; Provisional; Region: PRK05066
595495004039	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
595495004040	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
595495004041	malate dehydrogenase; Provisional; Region: PRK05086
595495004042	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
595495004043	NAD binding site [chemical binding]; other site
595495004044	dimerization interface [polypeptide binding]; other site
595495004045	Substrate binding site [chemical binding]; other site
595495004046	serine endoprotease; Provisional; Region: PRK10898
595495004047	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
595495004048	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
595495004049	serine endoprotease; Provisional; Region: PRK10139
595495004050	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
595495004051	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
595495004052	protein binding site [polypeptide binding]; other site
595495004053	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
595495004054	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
595495004055	hypothetical protein; Provisional; Region: PRK11677
595495004056	Predicted ATPase [General function prediction only]; Region: COG1485
595495004057	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
595495004058	23S rRNA interface [nucleotide binding]; other site
595495004059	L3 interface [polypeptide binding]; other site
595495004060	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
595495004061	stringent starvation protein A; Provisional; Region: sspA; PRK09481
595495004062	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
595495004063	C-terminal domain interface [polypeptide binding]; other site
595495004064	putative GSH binding site (G-site) [chemical binding]; other site
595495004065	dimer interface [polypeptide binding]; other site
595495004066	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
595495004067	dimer interface [polypeptide binding]; other site
595495004068	N-terminal domain interface [polypeptide binding]; other site
595495004069	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
595495004070	putative cryptic C4-dicarboxylate transporter DcuD; Provisional; Region: PRK09804
595495004071	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
595495004072	transcriptional regulator NanR; Provisional; Region: PRK03837
595495004073	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
595495004074	DNA-binding site [nucleotide binding]; DNA binding site
595495004075	FCD domain; Region: FCD; pfam07729
595495004076	N-acetylneuraminate lyase; Region: nanA; TIGR00683
595495004077	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
595495004078	inhibitor site; inhibition site
595495004079	active site
595495004080	dimer interface [polypeptide binding]; other site
595495004081	catalytic residue [active]
595495004082	putative sialic acid transporter; Provisional; Region: PRK03893
595495004083	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495004084	putative substrate translocation pore; other site
595495004085	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
595495004086	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
595495004087	putative active site cavity [active]
595495004088	N-acetylmannosamine kinase; Provisional; Region: PRK05082
595495004089	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
595495004090	nucleotide binding site [chemical binding]; other site
595495004091	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
595495004092	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
595495004093	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
595495004094	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
595495004095	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
595495004096	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
595495004097	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
595495004098	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
595495004099	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
595495004100	active site
595495004101	dimer interface [polypeptide binding]; other site
595495004102	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
595495004103	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
595495004104	active site
595495004105	FMN binding site [chemical binding]; other site
595495004106	substrate binding site [chemical binding]; other site
595495004107	3Fe-4S cluster binding site [ion binding]; other site
595495004108	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
595495004109	domain interface; other site
595495004110	radical SAM protein, TIGR01212 family; Region: TIGR01212
595495004111	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
595495004112	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
595495004113	putative active site [active]
595495004114	heme pocket [chemical binding]; other site
595495004115	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
595495004116	dimer interface [polypeptide binding]; other site
595495004117	phosphorylation site [posttranslational modification]
595495004118	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495004119	ATP binding site [chemical binding]; other site
595495004120	Mg2+ binding site [ion binding]; other site
595495004121	G-X-G motif; other site
595495004122	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495004123	active site
595495004124	phosphorylation site [posttranslational modification]
595495004125	intermolecular recognition site; other site
595495004126	dimerization interface [polypeptide binding]; other site
595495004127	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
595495004128	putative binding surface; other site
595495004129	active site
595495004130	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
595495004131	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
595495004132	conserved cys residue [active]
595495004133	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
595495004134	Transglycosylase; Region: Transgly; cl17702
595495004135	hypothetical protein; Provisional; Region: PRK10345
595495004136	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
595495004137	dimerization domain swap beta strand [polypeptide binding]; other site
595495004138	regulatory protein interface [polypeptide binding]; other site
595495004139	active site
595495004140	regulatory phosphorylation site [posttranslational modification]; other site
595495004141	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
595495004142	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
595495004143	active site
595495004144	phosphorylation site [posttranslational modification]
595495004145	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
595495004146	30S subunit binding site; other site
595495004147	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
595495004148	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
595495004149	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
595495004150	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
595495004151	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
595495004152	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
595495004153	Walker A/P-loop; other site
595495004154	ATP binding site [chemical binding]; other site
595495004155	Q-loop/lid; other site
595495004156	ABC transporter signature motif; other site
595495004157	Walker B; other site
595495004158	D-loop; other site
595495004159	H-loop/switch region; other site
595495004160	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
595495004161	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
595495004162	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
595495004163	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
595495004164	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
595495004165	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
595495004166	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
595495004167	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
595495004168	putative active site [active]
595495004169	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
595495004170	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
595495004171	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
595495004172	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
595495004173	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
595495004174	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
595495004175	Walker A/P-loop; other site
595495004176	ATP binding site [chemical binding]; other site
595495004177	Q-loop/lid; other site
595495004178	ABC transporter signature motif; other site
595495004179	Walker B; other site
595495004180	D-loop; other site
595495004181	H-loop/switch region; other site
595495004182	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
595495004183	conserved hypothetical integral membrane protein; Region: TIGR00056
595495004184	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
595495004185	mce related protein; Region: MCE; pfam02470
595495004186	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
595495004187	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
595495004188	anti sigma factor interaction site; other site
595495004189	regulatory phosphorylation site [posttranslational modification]; other site
595495004190	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
595495004191	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
595495004192	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
595495004193	hinge; other site
595495004194	active site
595495004195	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
595495004196	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
595495004197	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
595495004198	substrate binding pocket [chemical binding]; other site
595495004199	chain length determination region; other site
595495004200	substrate-Mg2+ binding site; other site
595495004201	catalytic residues [active]
595495004202	aspartate-rich region 1; other site
595495004203	active site lid residues [active]
595495004204	aspartate-rich region 2; other site
595495004205	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
595495004206	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
595495004207	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
595495004208	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
595495004209	EamA-like transporter family; Region: EamA; pfam00892
595495004210	EamA-like transporter family; Region: EamA; pfam00892
595495004211	GTPase CgtA; Reviewed; Region: obgE; PRK12298
595495004212	GTP1/OBG; Region: GTP1_OBG; pfam01018
595495004213	Obg GTPase; Region: Obg; cd01898
595495004214	G1 box; other site
595495004215	GTP/Mg2+ binding site [chemical binding]; other site
595495004216	Switch I region; other site
595495004217	G2 box; other site
595495004218	G3 box; other site
595495004219	Switch II region; other site
595495004220	G4 box; other site
595495004221	G5 box; other site
595495004222	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
595495004223	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
595495004224	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
595495004225	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
595495004226	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
595495004227	RNA-binding protein YhbY; Provisional; Region: PRK10343
595495004228	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
595495004229	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495004230	S-adenosylmethionine binding site [chemical binding]; other site
595495004231	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
595495004232	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495004233	Walker A motif; other site
595495004234	ATP binding site [chemical binding]; other site
595495004235	Walker B motif; other site
595495004236	arginine finger; other site
595495004237	Peptidase family M41; Region: Peptidase_M41; pfam01434
595495004238	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
595495004239	dihydropteroate synthase; Region: DHPS; TIGR01496
595495004240	substrate binding pocket [chemical binding]; other site
595495004241	dimer interface [polypeptide binding]; other site
595495004242	inhibitor binding site; inhibition site
595495004243	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
595495004244	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
595495004245	active site
595495004246	substrate binding site [chemical binding]; other site
595495004247	metal binding site [ion binding]; metal-binding site
595495004248	Preprotein translocase SecG subunit; Region: SecG; pfam03840
595495004249	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
595495004250	Sulfatase; Region: Sulfatase; pfam00884
595495004251	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
595495004252	ANP binding site [chemical binding]; other site
595495004253	Substrate Binding Site II [chemical binding]; other site
595495004254	Substrate Binding Site I [chemical binding]; other site
595495004255	ribosome maturation protein RimP; Reviewed; Region: PRK00092
595495004256	hypothetical protein; Provisional; Region: PRK14641
595495004257	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
595495004258	putative oligomer interface [polypeptide binding]; other site
595495004259	putative RNA binding site [nucleotide binding]; other site
595495004260	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
595495004261	NusA N-terminal domain; Region: NusA_N; pfam08529
595495004262	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
595495004263	RNA binding site [nucleotide binding]; other site
595495004264	homodimer interface [polypeptide binding]; other site
595495004265	NusA-like KH domain; Region: KH_5; pfam13184
595495004266	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
595495004267	G-X-X-G motif; other site
595495004268	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
595495004269	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
595495004270	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
595495004271	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
595495004272	translation initiation factor IF-2; Region: IF-2; TIGR00487
595495004273	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
595495004274	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
595495004275	G1 box; other site
595495004276	putative GEF interaction site [polypeptide binding]; other site
595495004277	GTP/Mg2+ binding site [chemical binding]; other site
595495004278	Switch I region; other site
595495004279	G2 box; other site
595495004280	G3 box; other site
595495004281	Switch II region; other site
595495004282	G4 box; other site
595495004283	G5 box; other site
595495004284	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
595495004285	Translation-initiation factor 2; Region: IF-2; pfam11987
595495004286	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
595495004287	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
595495004288	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
595495004289	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
595495004290	RNA binding site [nucleotide binding]; other site
595495004291	active site
595495004292	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
595495004293	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
595495004294	16S/18S rRNA binding site [nucleotide binding]; other site
595495004295	S13e-L30e interaction site [polypeptide binding]; other site
595495004296	25S rRNA binding site [nucleotide binding]; other site
595495004297	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
595495004298	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
595495004299	RNase E interface [polypeptide binding]; other site
595495004300	trimer interface [polypeptide binding]; other site
595495004301	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
595495004302	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
595495004303	RNase E interface [polypeptide binding]; other site
595495004304	trimer interface [polypeptide binding]; other site
595495004305	active site
595495004306	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
595495004307	putative nucleic acid binding region [nucleotide binding]; other site
595495004308	G-X-X-G motif; other site
595495004309	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
595495004310	RNA binding site [nucleotide binding]; other site
595495004311	domain interface; other site
595495004312	lipoprotein NlpI; Provisional; Region: PRK11189
595495004313	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
595495004314	binding surface
595495004315	TPR motif; other site
595495004316	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
595495004317	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
595495004318	ATP binding site [chemical binding]; other site
595495004319	Mg++ binding site [ion binding]; other site
595495004320	motif III; other site
595495004321	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
595495004322	nucleotide binding region [chemical binding]; other site
595495004323	ATP-binding site [chemical binding]; other site
595495004324	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
595495004325	putative RNA binding site [nucleotide binding]; other site
595495004326	tryptophan permease; Provisional; Region: PRK10483
595495004327	aromatic amino acid transport protein; Region: araaP; TIGR00837
595495004328	hypothetical protein; Provisional; Region: PRK10508
595495004329	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
595495004330	putative protease; Provisional; Region: PRK15447
595495004331	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
595495004332	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
595495004333	Peptidase family U32; Region: Peptidase_U32; pfam01136
595495004334	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
595495004335	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
595495004336	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
595495004337	Coenzyme A binding pocket [chemical binding]; other site
595495004338	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
595495004339	GIY-YIG motif/motif A; other site
595495004340	putative active site [active]
595495004341	putative metal binding site [ion binding]; other site
595495004342	hypothetical protein; Provisional; Region: PRK03467
595495004343	intracellular protease, PfpI family; Region: PfpI; TIGR01382
595495004344	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
595495004345	proposed catalytic triad [active]
595495004346	conserved cys residue [active]
595495004347	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
595495004348	NADH(P)-binding; Region: NAD_binding_10; pfam13460
595495004349	NAD binding site [chemical binding]; other site
595495004350	active site
595495004351	Predicted permease; Region: DUF318; pfam03773
595495004352	outer membrane lipoprotein; Provisional; Region: PRK11023
595495004353	BON domain; Region: BON; pfam04972
595495004354	BON domain; Region: BON; pfam04972
595495004355	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
595495004356	dimer interface [polypeptide binding]; other site
595495004357	active site
595495004358	TIGR00252 family protein; Region: TIGR00252
595495004359	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
595495004360	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
595495004361	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
595495004362	putative ligand binding site [chemical binding]; other site
595495004363	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
595495004364	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
595495004365	putative SAM binding site [chemical binding]; other site
595495004366	putative homodimer interface [polypeptide binding]; other site
595495004367	Fimbrial protein; Region: Fimbrial; pfam00419
595495004368	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
595495004369	PapC N-terminal domain; Region: PapC_N; pfam13954
595495004370	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
595495004371	PapC C-terminal domain; Region: PapC_C; pfam13953
595495004372	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
595495004373	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
595495004374	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
595495004375	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
595495004376	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
595495004377	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
595495004378	active site
595495004379	trimer interface [polypeptide binding]; other site
595495004380	allosteric site; other site
595495004381	active site lid [active]
595495004382	PTS system N-acetylgalactosamine-specific transporter subunit IID; Provisional; Region: PRK09855
595495004383	PTS system N-acetylgalactosamine-specific transporter subunit IIC; Provisional; Region: PRK09757
595495004384	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
595495004385	active site
595495004386	phosphorylation site [posttranslational modification]
595495004387	Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cd00453
595495004388	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
595495004389	active site
595495004390	intersubunit interface [polypeptide binding]; other site
595495004391	zinc binding site [ion binding]; other site
595495004392	Na+ binding site [ion binding]; other site
595495004393	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
595495004394	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
595495004395	dimer interface [polypeptide binding]; other site
595495004396	active site
595495004397	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
595495004398	putative active site [active]
595495004399	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
595495004400	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
595495004401	active site
595495004402	dimer interface [polypeptide binding]; other site
595495004403	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
595495004404	active pocket/dimerization site; other site
595495004405	active site
595495004406	phosphorylation site [posttranslational modification]
595495004407	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
595495004408	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
595495004409	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
595495004410	active site
595495004411	phosphorylation site [posttranslational modification]
595495004412	tagatose 6-phosphate aldolase subunit KbaZ; Provisional; Region: PRK15458
595495004413	DNA-binding transcriptional regulator AgaR; Provisional; Region: PRK09802
595495004414	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
595495004415	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
595495004416	Toxin with endonuclease activity YhaV; Region: Toxin_YhaV; pfam11663
595495004417	putative regulator PrlF; Provisional; Region: PRK09974
595495004418	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
595495004419	galactarate dehydratase; Region: galactar-dH20; TIGR03248
595495004420	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
595495004421	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
595495004422	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495004423	D-galactonate transporter; Region: 2A0114; TIGR00893
595495004424	putative substrate translocation pore; other site
595495004425	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
595495004426	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
595495004427	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
595495004428	glycerate kinase I; Provisional; Region: PRK10342
595495004429	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
595495004430	hypothetical protein; Provisional; Region: PRK09716
595495004431	DNA-binding transcriptional activator TdcR; Provisional; Region: PRK11424
595495004432	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
595495004433	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495004434	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
595495004435	putative substrate binding pocket [chemical binding]; other site
595495004436	putative dimerization interface [polypeptide binding]; other site
595495004437	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
595495004438	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
595495004439	tetramer interface [polypeptide binding]; other site
595495004440	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495004441	catalytic residue [active]
595495004442	threonine/serine transporter TdcC; Provisional; Region: PRK13629
595495004443	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
595495004444	propionate/acetate kinase; Provisional; Region: PRK12379
595495004445	Acetokinase family; Region: Acetate_kinase; cl17229
595495004446	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
595495004447	Pyruvate formate lyase 1; Region: PFL1; cd01678
595495004448	coenzyme A binding site [chemical binding]; other site
595495004449	active site
595495004450	catalytic residues [active]
595495004451	glycine loop; other site
595495004452	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
595495004453	homotrimer interaction site [polypeptide binding]; other site
595495004454	putative active site [active]
595495004455	L-serine dehydratase TdcG; Provisional; Region: PRK15040
595495004456	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
595495004457	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
595495004458	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
595495004459	serine transporter; Region: stp; TIGR00814
595495004460	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
595495004461	Pirin-related protein [General function prediction only]; Region: COG1741
595495004462	Pirin; Region: Pirin; pfam02678
595495004463	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495004464	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
595495004465	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
595495004466	dimerization interface [polypeptide binding]; other site
595495004467	Protein of unknown function (DUF805); Region: DUF805; pfam05656
595495004468	Predicted membrane protein [Function unknown]; Region: COG3152
595495004469	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
595495004470	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
595495004471	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
595495004472	putative dimer interface [polypeptide binding]; other site
595495004473	N-terminal domain interface [polypeptide binding]; other site
595495004474	putative substrate binding pocket (H-site) [chemical binding]; other site
595495004475	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495004476	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
595495004477	Predicted membrane protein [Function unknown]; Region: COG2259
595495004478	YqjK-like protein; Region: YqjK; pfam13997
595495004479	Predicted membrane protein [Function unknown]; Region: COG5393
595495004480	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
595495004481	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
595495004482	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
595495004483	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
595495004484	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
595495004485	DNA-binding transcriptional repressor ExuR; Provisional; Region: PRK11523
595495004486	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
595495004487	DNA-binding site [nucleotide binding]; DNA binding site
595495004488	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
595495004489	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
595495004490	putative fimbrial protein TcfA; Provisional; Region: PRK15308
595495004491	CS1 type fimbrial major subunit; Region: Fimbrial_CS1; pfam04449
595495004492	fimbrial outer membrane usher protein TcfC; Provisional; Region: PRK15310
595495004493	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
595495004494	CblD like pilus biogenesis initiator; Region: CblD; cl06460
595495004495	D-galactonate transporter; Region: 2A0114; TIGR00893
595495004496	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495004497	putative substrate translocation pore; other site
595495004498	Glucuronate isomerase; Region: UxaC; pfam02614
595495004499	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
595495004500	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
595495004501	galactarate dehydratase; Region: galactar-dH20; TIGR03248
595495004502	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
595495004503	Bacterial inner membrane protein; Region: Imp-YgjV; pfam10688
595495004504	serine/threonine transporter SstT; Provisional; Region: PRK13628
595495004505	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
595495004506	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
595495004507	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
595495004508	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
595495004509	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
595495004510	putative active site [active]
595495004511	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
595495004512	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
595495004513	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495004514	S-adenosylmethionine binding site [chemical binding]; other site
595495004515	Uncharacterized protein conserved in bacteria (DUF2136); Region: DUF2136; cl01912
595495004516	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
595495004517	non-specific DNA binding site [nucleotide binding]; other site
595495004518	salt bridge; other site
595495004519	sequence-specific DNA binding site [nucleotide binding]; other site
595495004520	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
595495004521	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
595495004522	active site
595495004523	FMN binding site [chemical binding]; other site
595495004524	2,4-decadienoyl-CoA binding site; other site
595495004525	catalytic residue [active]
595495004526	4Fe-4S cluster binding site [ion binding]; other site
595495004527	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
595495004528	alpha-glucosidase; Provisional; Region: PRK10137
595495004529	Protein of unknown function, DUF608; Region: DUF608; pfam04685
595495004530	Trehalase; Region: Trehalase; cl17346
595495004531	inner membrane transporter YjeM; Provisional; Region: PRK15238
595495004532	Domain of unknown function (DUF386); Region: DUF386; cl01047
595495004533	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495004534	Domain of unknown function (DUF386); Region: DUF386; cl01047
595495004535	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
595495004536	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
595495004537	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
595495004538	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
595495004539	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
595495004540	DNA-binding transcriptional repressor EbgR; Provisional; Region: PRK10339
595495004541	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
595495004542	DNA binding site [nucleotide binding]
595495004543	domain linker motif; other site
595495004544	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
595495004545	putative dimerization interface [polypeptide binding]; other site
595495004546	putative ligand binding site [chemical binding]; other site
595495004547	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
595495004548	dimer interface [polypeptide binding]; other site
595495004549	putative tRNA-binding site [nucleotide binding]; other site
595495004550	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
595495004551	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
595495004552	inhibitor-cofactor binding pocket; inhibition site
595495004553	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495004554	catalytic residue [active]
595495004555	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
595495004556	PAS fold; Region: PAS_3; pfam08447
595495004557	putative active site [active]
595495004558	heme pocket [chemical binding]; other site
595495004559	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
595495004560	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
595495004561	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
595495004562	dimer interface [polypeptide binding]; other site
595495004563	putative CheW interface [polypeptide binding]; other site
595495004564	Predicted transcriptional regulators [Transcription]; Region: COG1695
595495004565	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
595495004566	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
595495004567	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
595495004568	FAD binding pocket [chemical binding]; other site
595495004569	FAD binding motif [chemical binding]; other site
595495004570	phosphate binding motif [ion binding]; other site
595495004571	NAD binding pocket [chemical binding]; other site
595495004572	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
595495004573	active site
595495004574	SUMO-1 interface [polypeptide binding]; other site
595495004575	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
595495004576	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
595495004577	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
595495004578	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
595495004579	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
595495004580	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
595495004581	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
595495004582	DNA binding residues [nucleotide binding]
595495004583	DNA primase; Validated; Region: dnaG; PRK05667
595495004584	CHC2 zinc finger; Region: zf-CHC2; pfam01807
595495004585	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
595495004586	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
595495004587	active site
595495004588	metal binding site [ion binding]; metal-binding site
595495004589	interdomain interaction site; other site
595495004590	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
595495004591	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
595495004592	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
595495004593	UGMP family protein; Validated; Region: PRK09604
595495004594	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
595495004595	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
595495004596	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
595495004597	transmembrane helices; other site
595495004598	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
595495004599	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
595495004600	transcriptional activator TtdR; Provisional; Region: PRK09801
595495004601	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495004602	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
595495004603	putative effector binding pocket; other site
595495004604	putative dimerization interface [polypeptide binding]; other site
595495004605	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
595495004606	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
595495004607	homooctamer interface [polypeptide binding]; other site
595495004608	active site
595495004609	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
595495004610	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
595495004611	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
595495004612	active site
595495004613	NTP binding site [chemical binding]; other site
595495004614	metal binding triad [ion binding]; metal-binding site
595495004615	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
595495004616	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
595495004617	Zn2+ binding site [ion binding]; other site
595495004618	Mg2+ binding site [ion binding]; other site
595495004619	SH3 domain-containing protein; Provisional; Region: PRK10884
595495004620	Bacterial SH3 domain homologues; Region: SH3b; smart00287
595495004621	Uncharacterized conserved protein [Function unknown]; Region: COG3025
595495004622	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
595495004623	putative active site [active]
595495004624	putative metal binding residues [ion binding]; other site
595495004625	signature motif; other site
595495004626	putative triphosphate binding site [ion binding]; other site
595495004627	CHAD domain; Region: CHAD; pfam05235
595495004628	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
595495004629	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
595495004630	metal binding triad; other site
595495004631	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
595495004632	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
595495004633	metal binding triad; other site
595495004634	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
595495004635	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
595495004636	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
595495004637	putative ribose interaction site [chemical binding]; other site
595495004638	putative ADP binding site [chemical binding]; other site
595495004639	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
595495004640	active site
595495004641	nucleotide binding site [chemical binding]; other site
595495004642	HIGH motif; other site
595495004643	KMSKS motif; other site
595495004644	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
595495004645	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
595495004646	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
595495004647	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
595495004648	Fimbrial protein; Region: Fimbrial; pfam00419
595495004649	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
595495004650	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
595495004651	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
595495004652	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
595495004653	PapC N-terminal domain; Region: PapC_N; pfam13954
595495004654	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
595495004655	PapC C-terminal domain; Region: PapC_C; pfam13953
595495004656	putative fimbrial protein; Provisional; Region: PRK09733
595495004657	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
595495004658	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
595495004659	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
595495004660	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
595495004661	zinc transporter ZupT; Provisional; Region: PRK04201
595495004662	ZIP Zinc transporter; Region: Zip; pfam02535
595495004663	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
595495004664	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
595495004665	putative active site [active]
595495004666	metal binding site [ion binding]; metal-binding site
595495004667	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
595495004668	hypothetical protein; Provisional; Region: PRK11653
595495004669	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
595495004670	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
595495004671	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
595495004672	dimer interface [polypeptide binding]; other site
595495004673	ADP-ribose binding site [chemical binding]; other site
595495004674	active site
595495004675	nudix motif; other site
595495004676	metal binding site [ion binding]; metal-binding site
595495004677	putative dehydrogenase; Provisional; Region: PRK11039
595495004678	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
595495004679	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
595495004680	active site
595495004681	metal binding site [ion binding]; metal-binding site
595495004682	hexamer interface [polypeptide binding]; other site
595495004683	esterase YqiA; Provisional; Region: PRK11071
595495004684	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
595495004685	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
595495004686	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495004687	ATP binding site [chemical binding]; other site
595495004688	Mg2+ binding site [ion binding]; other site
595495004689	G-X-G motif; other site
595495004690	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
595495004691	anchoring element; other site
595495004692	dimer interface [polypeptide binding]; other site
595495004693	ATP binding site [chemical binding]; other site
595495004694	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
595495004695	active site
595495004696	metal binding site [ion binding]; metal-binding site
595495004697	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
595495004698	Uncharacterized conserved protein [Function unknown]; Region: COG1359
595495004699	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
595495004700	sensor protein QseC; Provisional; Region: PRK10337
595495004701	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
595495004702	dimer interface [polypeptide binding]; other site
595495004703	phosphorylation site [posttranslational modification]
595495004704	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495004705	ATP binding site [chemical binding]; other site
595495004706	Mg2+ binding site [ion binding]; other site
595495004707	G-X-G motif; other site
595495004708	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
595495004709	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495004710	active site
595495004711	phosphorylation site [posttranslational modification]
595495004712	intermolecular recognition site; other site
595495004713	dimerization interface [polypeptide binding]; other site
595495004714	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
595495004715	DNA binding site [nucleotide binding]
595495004716	TIGR00156 family protein; Region: TIGR00156
595495004717	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
595495004718	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
595495004719	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
595495004720	CAP-like domain; other site
595495004721	active site
595495004722	primary dimer interface [polypeptide binding]; other site
595495004723	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
595495004724	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
595495004725	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
595495004726	putative acyl-acceptor binding pocket; other site
595495004727	FtsI repressor; Provisional; Region: PRK10883
595495004728	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
595495004729	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
595495004730	hypothetical protein; Provisional; Region: PRK01254
595495004731	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
595495004732	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
595495004733	putative outer membrane lipoprotein; Provisional; Region: PRK09973
595495004734	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
595495004735	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
595495004736	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
595495004737	active site
595495004738	catalytic tetrad [active]
595495004739	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
595495004740	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
595495004741	dimer interface [polypeptide binding]; other site
595495004742	active site
595495004743	metal binding site [ion binding]; metal-binding site
595495004744	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
595495004745	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
595495004746	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495004747	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495004748	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
595495004749	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
595495004750	cystathionine beta-lyase; Provisional; Region: PRK08114
595495004751	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
595495004752	homodimer interface [polypeptide binding]; other site
595495004753	substrate-cofactor binding pocket; other site
595495004754	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495004755	catalytic residue [active]
595495004756	biopolymer transport protein ExbB; Provisional; Region: PRK10414
595495004757	biopolymer transport protein ExbD; Provisional; Region: PRK11267
595495004758	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
595495004759	oxidoreductase; Provisional; Region: PRK07985
595495004760	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
595495004761	NAD binding site [chemical binding]; other site
595495004762	metal binding site [ion binding]; metal-binding site
595495004763	active site
595495004764	hypothetical protein; Provisional; Region: PRK05208
595495004765	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
595495004766	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
595495004767	active site
595495004768	catalytic tetrad [active]
595495004769	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
595495004770	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
595495004771	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
595495004772	hydrogenase 2 small subunit; Provisional; Region: PRK10468
595495004773	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
595495004774	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
595495004775	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
595495004776	4Fe-4S binding domain; Region: Fer4_6; pfam12837
595495004777	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
595495004778	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
595495004779	hydrogenase 2 large subunit; Provisional; Region: PRK10467
595495004780	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
595495004781	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
595495004782	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
595495004783	putative substrate-binding site; other site
595495004784	nickel binding site [ion binding]; other site
595495004785	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
595495004786	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
595495004787	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
595495004788	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
595495004789	putative S-transferase; Provisional; Region: PRK11752
595495004790	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
595495004791	C-terminal domain interface [polypeptide binding]; other site
595495004792	GSH binding site (G-site) [chemical binding]; other site
595495004793	dimer interface [polypeptide binding]; other site
595495004794	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
595495004795	dimer interface [polypeptide binding]; other site
595495004796	N-terminal domain interface [polypeptide binding]; other site
595495004797	active site
595495004798	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
595495004799	CHAP domain; Region: CHAP; pfam05257
595495004800	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
595495004801	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
595495004802	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
595495004803	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
595495004804	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
595495004805	TMP-binding site; other site
595495004806	ATP-binding site [chemical binding]; other site
595495004807	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
595495004808	thymidylate kinase; Validated; Region: tmk; PRK00698
595495004809	TMP-binding site; other site
595495004810	ATP-binding site [chemical binding]; other site
595495004811	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
595495004812	Thymidylate kinase; Region: Thymidylate_kin; pfam02223
595495004813	active site
595495004814	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
595495004815	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
595495004816	Bacterial protein of unknown function (YtfJ_HI0045); Region: YtfJ_HI0045; pfam09695
595495004817	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
595495004818	Predicted permeases [General function prediction only]; Region: COG0795
595495004819	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
595495004820	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
595495004821	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
595495004822	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
595495004823	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
595495004824	catalytic residue [active]
595495004825	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
595495004826	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
595495004827	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
595495004828	NAD(P) binding site [chemical binding]; other site
595495004829	active site
595495004830	acyl-CoA synthetase; Validated; Region: PRK09192
595495004831	Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931
595495004832	acyl-activating enzyme (AAE) consensus motif; other site
595495004833	active site
595495004834	DNA-binding transcriptional regulator GlcC; Provisional; Region: PRK09990
595495004835	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
595495004836	DNA-binding site [nucleotide binding]; DNA binding site
595495004837	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
595495004838	glycolate oxidase subunit GlcD; Provisional; Region: PRK11230
595495004839	FAD binding domain; Region: FAD_binding_4; pfam01565
595495004840	glycolate oxidase FAD binding subunit; Provisional; Region: glcE; PRK11282
595495004841	FAD binding domain; Region: FAD_binding_4; pfam01565
595495004842	glycolate oxidase iron-sulfur subunit; Provisional; Region: glcF; PRK11274
595495004843	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
595495004844	Cysteine-rich domain; Region: CCG; pfam02754
595495004845	Cysteine-rich domain; Region: CCG; pfam02754
595495004846	hypothetical protein; Provisional; Region: PRK09732
595495004847	Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate...; Region: malate_synt_G; cd00728
595495004848	active site
595495004849	glycolate transporter; Provisional; Region: PRK09695
595495004850	L-lactate permease; Region: Lactate_perm; cl00701
595495004851	Domain of unknown function (DUF4092); Region: DUF4092; pfam13322
595495004852	Peptidase M60-like family; Region: M60-like; pfam13402
595495004853	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
595495004854	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
595495004855	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
595495004856	putative type II secretion protein GspC; Provisional; Region: PRK09681
595495004857	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
595495004858	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
595495004859	type II secretion system protein D; Region: type_II_gspD; TIGR02517
595495004860	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
595495004861	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
595495004862	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
595495004863	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
595495004864	type II secretion system protein E; Region: type_II_gspE; TIGR02533
595495004865	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
595495004866	Walker A motif; other site
595495004867	ATP binding site [chemical binding]; other site
595495004868	Walker B motif; other site
595495004869	type II secretion system protein F; Region: GspF; TIGR02120
595495004870	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
595495004871	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
595495004872	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
595495004873	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
595495004874	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
595495004875	Prokaryotic N-terminal methylation motif; Region: N_methyl; pfam07963
595495004876	Type II transport protein GspH; Region: GspH; pfam12019
595495004877	type II secretion system protein I; Region: gspI; TIGR01707
595495004878	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
595495004879	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
595495004880	type II secretion system protein J; Region: gspJ; TIGR01711
595495004881	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
595495004882	Type II secretion system (T2SS), protein K; Region: T2SK; pfam03934
595495004883	type II secretion system protein L; Region: typeII_sec_gspL; TIGR01709
595495004884	GspL-like protein; Provisional; Region: PRK09662
595495004885	putative general secretion pathway protein YghD; Provisional; Region: PRK09731
595495004886	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
595495004887	ornithine decarboxylase; Provisional; Region: PRK13578
595495004888	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
595495004889	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
595495004890	homodimer interface [polypeptide binding]; other site
595495004891	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495004892	catalytic residue [active]
595495004893	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
595495004894	nucleoside transporter; Region: 2A0110; TIGR00889
595495004895	murein transglycosylase C; Provisional; Region: mltC; PRK11671
595495004896	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
595495004897	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
595495004898	N-acetyl-D-glucosamine binding site [chemical binding]; other site
595495004899	catalytic residue [active]
595495004900	oxidative damage protection protein; Provisional; Region: PRK05408
595495004901	adenine DNA glycosylase; Provisional; Region: PRK10880
595495004902	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
595495004903	minor groove reading motif; other site
595495004904	helix-hairpin-helix signature motif; other site
595495004905	substrate binding pocket [chemical binding]; other site
595495004906	active site
595495004907	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
595495004908	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
595495004909	DNA binding and oxoG recognition site [nucleotide binding]
595495004910	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
595495004911	hypothetical protein; Provisional; Region: PRK11702
595495004912	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
595495004913	hypothetical protein; Provisional; Region: PRK10626
595495004914	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
595495004915	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
595495004916	homodimer interface [polypeptide binding]; other site
595495004917	active site
595495004918	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
595495004919	HemN family oxidoreductase; Provisional; Region: PRK05660
595495004920	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495004921	FeS/SAM binding site; other site
595495004922	HemN C-terminal domain; Region: HemN_C; pfam06969
595495004923	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
595495004924	active site
595495004925	dimerization interface [polypeptide binding]; other site
595495004926	hypothetical protein; Validated; Region: PRK05090
595495004927	YGGT family; Region: YGGT; pfam02325
595495004928	YGGT family; Region: YGGT; pfam02325
595495004929	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
595495004930	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
595495004931	catalytic residue [active]
595495004932	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
595495004933	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
595495004934	Walker A motif; other site
595495004935	ATP binding site [chemical binding]; other site
595495004936	Walker B motif; other site
595495004937	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
595495004938	hypothetical protein; Validated; Region: PRK00228
595495004939	glutathione synthetase; Provisional; Region: PRK05246
595495004940	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
595495004941	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
595495004942	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
595495004943	RNA methyltransferase, RsmE family; Region: TIGR00046
595495004944	DNA-specific endonuclease I; Provisional; Region: PRK15137
595495004945	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
595495004946	hypothetical protein; Provisional; Region: PRK04860
595495004947	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
595495004948	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
595495004949	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495004950	putative substrate translocation pore; other site
595495004951	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495004952	S-adenosylmethionine synthetase; Validated; Region: PRK05250
595495004953	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
595495004954	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
595495004955	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
595495004956	Protein of unknown function (DUF2684); Region: DUF2684; pfam10885
595495004957	Virulence promoting factor; Region: YqgB; pfam11036
595495004958	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
595495004959	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
595495004960	dimer interface [polypeptide binding]; other site
595495004961	active site
595495004962	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
595495004963	catalytic residues [active]
595495004964	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
595495004965	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
595495004966	agmatinase; Region: agmatinase; TIGR01230
595495004967	oligomer interface [polypeptide binding]; other site
595495004968	putative active site [active]
595495004969	Mn binding site [ion binding]; other site
595495004970	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
595495004971	transketolase; Reviewed; Region: PRK12753
595495004972	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
595495004973	TPP-binding site [chemical binding]; other site
595495004974	dimer interface [polypeptide binding]; other site
595495004975	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
595495004976	PYR/PP interface [polypeptide binding]; other site
595495004977	dimer interface [polypeptide binding]; other site
595495004978	TPP binding site [chemical binding]; other site
595495004979	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
595495004980	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
595495004981	active site
595495004982	phosphorylation site [posttranslational modification]
595495004983	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
595495004984	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
595495004985	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
595495004986	active site
595495004987	P-loop; other site
595495004988	phosphorylation site [posttranslational modification]
595495004989	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
595495004990	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
595495004991	putative NAD(P) binding site [chemical binding]; other site
595495004992	catalytic Zn binding site [ion binding]; other site
595495004993	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
595495004994	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
595495004995	putative active site [active]
595495004996	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
595495004997	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10022
595495004998	nucleoside triphosphate hydrolase domain-containing protein; Reviewed; Region: PRK09270
595495004999	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
595495005000	active site
595495005001	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
595495005002	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
595495005003	Walker A/P-loop; other site
595495005004	ATP binding site [chemical binding]; other site
595495005005	Q-loop/lid; other site
595495005006	ABC transporter signature motif; other site
595495005007	Walker B; other site
595495005008	D-loop; other site
595495005009	H-loop/switch region; other site
595495005010	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
595495005011	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
595495005012	Walker A/P-loop; other site
595495005013	ATP binding site [chemical binding]; other site
595495005014	Q-loop/lid; other site
595495005015	ABC transporter signature motif; other site
595495005016	Walker B; other site
595495005017	D-loop; other site
595495005018	H-loop/switch region; other site
595495005019	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
595495005020	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
595495005021	trimer interface [polypeptide binding]; other site
595495005022	putative Zn binding site [ion binding]; other site
595495005023	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
595495005024	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
595495005025	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
595495005026	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
595495005027	Phosphoglycerate kinase; Region: PGK; pfam00162
595495005028	substrate binding site [chemical binding]; other site
595495005029	hinge regions; other site
595495005030	ADP binding site [chemical binding]; other site
595495005031	catalytic site [active]
595495005032	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
595495005033	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
595495005034	active site
595495005035	intersubunit interface [polypeptide binding]; other site
595495005036	zinc binding site [ion binding]; other site
595495005037	Na+ binding site [ion binding]; other site
595495005038	mechanosensitive channel MscS; Provisional; Region: PRK10334
595495005039	Mechanosensitive ion channel; Region: MS_channel; pfam00924
595495005040	arginine exporter protein; Provisional; Region: PRK09304
595495005041	Uncharacterized conserved protein [Function unknown]; Region: COG2968
595495005042	oxidative stress defense protein; Provisional; Region: PRK11087
595495005043	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495005044	Transcriptional regulator [Transcription]; Region: LysR; COG0583
595495005045	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
595495005046	dimerization interface [polypeptide binding]; other site
595495005047	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
595495005048	succinate CoA transferase; Region: YgfH_subfam; TIGR03458
595495005049	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
595495005050	methylmalonyl-CoA decarboxylase; Provisional; Region: PRK11423
595495005051	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
595495005052	substrate binding site [chemical binding]; other site
595495005053	oxyanion hole (OAH) forming residues; other site
595495005054	trimer interface [polypeptide binding]; other site
595495005055	membrane ATPase/protein kinase; Provisional; Region: PRK09435
595495005056	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
595495005057	Walker A; other site
595495005058	methylmalonyl-CoA mutase; Reviewed; Region: PRK09426
595495005059	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Alpha subunit-like subfamily; contains proteins similar to the alpha subunit of Propionbacterium shermanni MCM, as well as human and E. coli MCM. Members of this subfamily contain...; Region: MM_CoA_mutase_alpha_like; cd03679
595495005060	active site
595495005061	substrate binding site [chemical binding]; other site
595495005062	coenzyme B12 binding site [chemical binding]; other site
595495005063	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
595495005064	B12 binding site [chemical binding]; other site
595495005065	cobalt ligand [ion binding]; other site
595495005066	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
595495005067	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495005068	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
595495005069	putative dimerization interface [polypeptide binding]; other site
595495005070	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
595495005071	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
595495005072	tetramer (dimer of dimers) interface [polypeptide binding]; other site
595495005073	active site
595495005074	dimer interface [polypeptide binding]; other site
595495005075	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
595495005076	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
595495005077	ligand binding site [chemical binding]; other site
595495005078	NAD binding site [chemical binding]; other site
595495005079	tetramer interface [polypeptide binding]; other site
595495005080	catalytic site [active]
595495005081	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
595495005082	L-serine binding site [chemical binding]; other site
595495005083	ACT domain interface; other site
595495005084	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
595495005085	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
595495005086	Z-ring-associated protein; Provisional; Region: PRK10972
595495005087	hypothetical protein; Reviewed; Region: PRK01736
595495005088	proline aminopeptidase P II; Provisional; Region: PRK10879
595495005089	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
595495005090	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
595495005091	active site
595495005092	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
595495005093	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
595495005094	oxidoreductase; Provisional; Region: PRK08013
595495005095	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
595495005096	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
595495005097	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
595495005098	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
595495005099	lipoyl attachment site [posttranslational modification]; other site
595495005100	glycine dehydrogenase; Provisional; Region: PRK05367
595495005101	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
595495005102	tetramer interface [polypeptide binding]; other site
595495005103	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495005104	catalytic residue [active]
595495005105	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
595495005106	tetramer interface [polypeptide binding]; other site
595495005107	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495005108	catalytic residue [active]
595495005109	putative NAD(P)-binding oxidoreductase; Provisional; Region: PRK09730
595495005110	classical (c) SDRs; Region: SDR_c; cd05233
595495005111	NAD(P) binding site [chemical binding]; other site
595495005112	active site
595495005113	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
595495005114	beta-galactosidase; Region: BGL; TIGR03356
595495005115	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
595495005116	hemolysin; Provisional; Region: PRK15087
595495005117	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
595495005118	putative global regulator; Reviewed; Region: PRK09559
595495005119	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
595495005120	hypothetical protein; Provisional; Region: PRK10878
595495005121	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
595495005122	flavodoxin FldB; Provisional; Region: PRK12359
595495005123	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
595495005124	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
595495005125	active site
595495005126	Int/Topo IB signature motif; other site
595495005127	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
595495005128	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
595495005129	dimerization domain [polypeptide binding]; other site
595495005130	dimer interface [polypeptide binding]; other site
595495005131	catalytic residues [active]
595495005132	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
595495005133	DHH family; Region: DHH; pfam01368
595495005134	DHHA1 domain; Region: DHHA1; pfam02272
595495005135	peptide chain release factor 2; Provisional; Region: PRK08787
595495005136	This domain is found in peptide chain release factors; Region: PCRF; smart00937
595495005137	RF-1 domain; Region: RF-1; pfam00472
595495005138	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
595495005139	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
595495005140	dimer interface [polypeptide binding]; other site
595495005141	putative anticodon binding site; other site
595495005142	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
595495005143	motif 1; other site
595495005144	active site
595495005145	motif 2; other site
595495005146	motif 3; other site
595495005147	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
595495005148	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
595495005149	active site
595495005150	metal binding site [ion binding]; metal-binding site
595495005151	nudix motif; other site
595495005152	xanthine permease; Region: pbuX; TIGR03173
595495005153	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12809
595495005154	4Fe-4S binding domain; Region: Fer4; pfam00037
595495005155	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
595495005156	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
595495005157	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
595495005158	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
595495005159	guanine deaminase; Provisional; Region: PRK09228
595495005160	Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303
595495005161	active site
595495005162	uracil-xanthine permease; Region: ncs2; TIGR00801
595495005163	putative hypoxanthine oxidase; Provisional; Region: PRK09800
595495005164	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
595495005165	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
595495005166	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
595495005167	probable selenate reductase, FAD-binding subunit; Region: Se_sel_red_FAD; TIGR03312
595495005168	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
595495005169	putative selenium metabolism protein SsnA; Region: Se_ssnA; TIGR03314
595495005170	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
595495005171	active site
595495005172	putative substrate binding pocket [chemical binding]; other site
595495005173	putative selenate reductase subunit YgfK; Provisional; Region: PRK09853
595495005174	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
595495005175	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
595495005176	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
595495005177	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
595495005178	Ligand binding site; other site
595495005179	metal-binding site
595495005180	probable selenium-dependent hydroxylase accessory protein YqeC; Region: TIGR03172
595495005181	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
595495005182	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
595495005183	XdhC Rossmann domain; Region: XdhC_C; pfam13478
595495005184	selenium-dependent molybdenum hydroxylase system protein, YqeB family; Region: matur_yqeB; TIGR03309
595495005185	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
595495005186	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
595495005187	carbamate kinase; Reviewed; Region: PRK12686
595495005188	putative substrate binding site [chemical binding]; other site
595495005189	homodimer interface [polypeptide binding]; other site
595495005190	nucleotide binding site [chemical binding]; other site
595495005191	nucleotide binding site [chemical binding]; other site
595495005192	D-hydantoinase; Region: D-hydantoinase; TIGR02033
595495005193	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
595495005194	tetramer interface [polypeptide binding]; other site
595495005195	active site
595495005196	peptidase; Reviewed; Region: PRK13004
595495005197	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649
595495005198	putative metal binding site [ion binding]; other site
595495005199	putative dimer interface [polypeptide binding]; other site
595495005200	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
595495005201	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
595495005202	catalytic residue [active]
595495005203	aspartate/ornithine carbamoyltransferase family protein; Validated; Region: PRK07200
595495005204	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
595495005205	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
595495005206	GAF domain; Region: GAF; cl17456
595495005207	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
595495005208	PAS domain; Region: PAS; smart00091
595495005209	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495005210	Walker A motif; other site
595495005211	ATP binding site [chemical binding]; other site
595495005212	Walker B motif; other site
595495005213	arginine finger; other site
595495005214	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
595495005215	xanthine dehydrogenase subunit XdhC; Provisional; Region: PRK09908
595495005216	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
595495005217	catalytic loop [active]
595495005218	iron binding site [ion binding]; other site
595495005219	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
595495005220	xanthine dehydrogenase subunit XdhB; Provisional; Region: PRK09971
595495005221	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
595495005222	xanthine dehydrogenase subunit XdhA; Provisional; Region: PRK09970
595495005223	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
595495005224	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
595495005225	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
595495005226	Peptidase family M23; Region: Peptidase_M23; pfam01551
595495005227	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
595495005228	type III secretion system protein SpaO; Validated; Region: PRK08158
595495005229	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
595495005230	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
595495005231	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495005232	type III secretion protein SpaR/YscT/HrcT; Region: fliR_like_III; TIGR01401
595495005233	type III secretion system protein SpaS; Validated; Region: PRK08156
595495005234	type III secretion system protein SpaS; Validated; Region: PRK08156
595495005235	InvH outer membrane lipoprotein; Region: InvH; pfam04741
595495005236	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
595495005237	DNA binding residues [nucleotide binding]
595495005238	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327; cl12363
595495005239	Type III secretion system protein PrgH-EprH (PrgH); Region: PrgH; pfam09480
595495005240	Type III secretion needle MxiH like; Region: MxiH; cl09641
595495005241	type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325
595495005242	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
595495005243	Bacterial type III secretion apparatus protein (OrgA_MxiK); Region: OrgA_MxiK; cl09716
595495005244	invasion protein OrgB; Provisional; Region: PRK15322
595495005245	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
595495005246	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
595495005247	N-acetyl-D-glucosamine binding site [chemical binding]; other site
595495005248	catalytic residue [active]
595495005249	transcriptional regulator; Provisional; Region: PRK11906
595495005250	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
595495005251	DNA binding site [nucleotide binding]
595495005252	type III secretion low calcium response chaperone LcrH/SycD; Region: LcrH_SycD; TIGR02552
595495005253	Tetratricopeptide repeat; Region: TPR_3; pfam07720
595495005254	Tetratricopeptide repeat; Region: TPR_3; pfam07720
595495005255	hyperosmolarity resistance protein Ebh, N-terminal domain; Region: hyperosmo_Ebh; TIGR04264
595495005256	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
595495005257	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
595495005258	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
595495005259	DNA binding residues [nucleotide binding]
595495005260	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
595495005261	serine transporter; Region: stp; TIGR00814
595495005262	putative acyltransferase; Provisional; Region: PRK05790
595495005263	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
595495005264	dimer interface [polypeptide binding]; other site
595495005265	active site
595495005266	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
595495005267	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
595495005268	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
595495005269	NADP binding site [chemical binding]; other site
595495005270	homodimer interface [polypeptide binding]; other site
595495005271	active site
595495005272	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
595495005273	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495005274	putative substrate translocation pore; other site
595495005275	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495005276	putative racemase; Provisional; Region: PRK10200
595495005277	aspartate racemase; Region: asp_race; TIGR00035
595495005278	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
595495005279	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495005280	The C-terminal substrate binding domain of LysR, transcriptional regulator for lysine biosynthesis, contains the type 2 periplasmic binding fold; Region: PBP2_LysR; cd08456
595495005281	putative dimerization interface [polypeptide binding]; other site
595495005282	diaminopimelate decarboxylase; Provisional; Region: PRK11165
595495005283	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
595495005284	active site
595495005285	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
595495005286	substrate binding site [chemical binding]; other site
595495005287	catalytic residues [active]
595495005288	dimer interface [polypeptide binding]; other site
595495005289	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
595495005290	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
595495005291	DNA binding site [nucleotide binding]
595495005292	domain linker motif; other site
595495005293	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
595495005294	dimerization interface (closed form) [polypeptide binding]; other site
595495005295	ligand binding site [chemical binding]; other site
595495005296	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
595495005297	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
595495005298	putative acyl-acceptor binding pocket; other site
595495005299	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
595495005300	acyl-activating enzyme (AAE) consensus motif; other site
595495005301	putative AMP binding site [chemical binding]; other site
595495005302	lysophospholipid transporter LplT; Provisional; Region: PRK11195
595495005303	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495005304	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
595495005305	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
595495005306	active site
595495005307	catalytic tetrad [active]
595495005308	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
595495005309	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
595495005310	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
595495005311	putative DNA-binding cleft [nucleotide binding]; other site
595495005312	putative DNA clevage site; other site
595495005313	molecular lever; other site
595495005314	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
595495005315	putative active site [active]
595495005316	Ap4A binding site [chemical binding]; other site
595495005317	nudix motif; other site
595495005318	putative metal binding site [ion binding]; other site
595495005319	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
595495005320	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
595495005321	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
595495005322	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
595495005323	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
595495005324	prolipoprotein diacylglyceryl transferase; Region: lgt; TIGR00544
595495005325	thymidylate synthase; Reviewed; Region: thyA; PRK01827
595495005326	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
595495005327	dimerization interface [polypeptide binding]; other site
595495005328	active site
595495005329	hypothetical protein; Provisional; Region: PRK10506
595495005330	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
595495005331	hypothetical protein; Provisional; Region: PRK10557
595495005332	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
595495005333	hypothetical protein; Provisional; Region: PRK11521
595495005334	hypothetical protein; Provisional; Region: PRK10332
595495005335	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
595495005336	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
595495005337	exodeoxyribonuclease V, gamma subunit; Region: recC; TIGR01450
595495005338	protease3; Provisional; Region: PRK15101
595495005339	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
595495005340	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
595495005341	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
595495005342	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
595495005343	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
595495005344	AAA domain; Region: AAA_30; pfam13604
595495005345	Family description; Region: UvrD_C_2; pfam13538
595495005346	N-acetylglutamate synthase; Validated; Region: PRK05279
595495005347	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
595495005348	putative feedback inhibition sensing region; other site
595495005349	putative nucleotide binding site [chemical binding]; other site
595495005350	putative substrate binding site [chemical binding]; other site
595495005351	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
595495005352	Coenzyme A binding pocket [chemical binding]; other site
595495005353	AMIN domain; Region: AMIN; pfam11741
595495005354	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
595495005355	active site
595495005356	metal binding site [ion binding]; metal-binding site
595495005357	ROS/MUCR transcriptional regulator protein; Region: ROS_MUCR; pfam05443
595495005358	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
595495005359	ImpA domain protein; Region: DUF3702; pfam12486
595495005360	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
595495005361	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
595495005362	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
595495005363	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
595495005364	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
595495005365	FlgD Tudor-like domain; Region: FLgD_tudor; cl17881
595495005366	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
595495005367	Transposase; Region: HTH_Tnp_1; cl17663
595495005368	Integrase core domain; Region: rve; pfam00665
595495005369	DDE domain; Region: DDE_Tnp_IS240; pfam13610
595495005370	Integrase core domain; Region: rve_3; pfam13683
595495005371	PAAR motif; Region: PAAR_motif; pfam05488
595495005372	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
595495005373	PAAR motif; Region: PAAR_motif; pfam05488
595495005374	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
595495005375	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
595495005376	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
595495005377	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
595495005378	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
595495005379	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
595495005380	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
595495005381	N-acetyl-D-glucosamine binding site [chemical binding]; other site
595495005382	catalytic residue [active]
595495005383	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
595495005384	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
595495005385	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
595495005386	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
595495005387	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4253
595495005388	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
595495005389	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
595495005390	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
595495005391	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
595495005392	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4253
595495005393	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
595495005394	Clp amino terminal domain; Region: Clp_N; pfam02861
595495005395	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495005396	Walker A motif; other site
595495005397	ATP binding site [chemical binding]; other site
595495005398	Walker B motif; other site
595495005399	arginine finger; other site
595495005400	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495005401	Walker A motif; other site
595495005402	ATP binding site [chemical binding]; other site
595495005403	Walker B motif; other site
595495005404	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
595495005405	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
595495005406	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
595495005407	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
595495005408	ligand binding site [chemical binding]; other site
595495005409	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850
595495005410	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
595495005411	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
595495005412	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
595495005413	Protein of unknown function (DUF877); Region: DUF877; pfam05943
595495005414	Protein of unknown function (DUF770); Region: DUF770; pfam05591
595495005415	murein transglycosylase A; Provisional; Region: mltA; PRK11162
595495005416	MltA specific insert domain; Region: MltA; pfam03562
595495005417	3D domain; Region: 3D; pfam06725
595495005418	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
595495005419	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
595495005420	putative ATP binding site [chemical binding]; other site
595495005421	putative substrate interface [chemical binding]; other site
595495005422	CsdA-binding activator; Provisional; Region: PRK15019
595495005423	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
595495005424	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
595495005425	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
595495005426	catalytic residue [active]
595495005427	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
595495005428	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
595495005429	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495005430	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
595495005431	dimerization interface [polypeptide binding]; other site
595495005432	substrate binding pocket [chemical binding]; other site
595495005433	hypothetical protein; Provisional; Region: PRK10873
595495005434	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
595495005435	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
595495005436	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
595495005437	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
595495005438	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
595495005439	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
595495005440	L-fuculokinase; Provisional; Region: PRK10331
595495005441	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
595495005442	nucleotide binding site [chemical binding]; other site
595495005443	L-fucose isomerase; Provisional; Region: fucI; PRK10991
595495005444	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
595495005445	hexamer (dimer of trimers) interface [polypeptide binding]; other site
595495005446	trimer interface [polypeptide binding]; other site
595495005447	substrate binding site [chemical binding]; other site
595495005448	Mn binding site [ion binding]; other site
595495005449	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
595495005450	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495005451	putative substrate translocation pore; other site
595495005452	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
595495005453	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
595495005454	intersubunit interface [polypeptide binding]; other site
595495005455	active site
595495005456	Zn2+ binding site [ion binding]; other site
595495005457	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
595495005458	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495005459	dimer interface [polypeptide binding]; other site
595495005460	active site
595495005461	metal binding site [ion binding]; metal-binding site
595495005462	flap endonuclease-like protein; Provisional; Region: PRK09482
595495005463	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
595495005464	active site
595495005465	metal binding site 1 [ion binding]; metal-binding site
595495005466	putative 5' ssDNA interaction site; other site
595495005467	metal binding site 3; metal-binding site
595495005468	metal binding site 2 [ion binding]; metal-binding site
595495005469	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
595495005470	putative DNA binding site [nucleotide binding]; other site
595495005471	putative metal binding site [ion binding]; other site
595495005472	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
595495005473	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
595495005474	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
595495005475	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
595495005476	serine transporter; Region: stp; TIGR00814
595495005477	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
595495005478	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
595495005479	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
595495005480	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
595495005481	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
595495005482	SecY interacting protein Syd; Provisional; Region: PRK04968
595495005483	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
595495005484	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
595495005485	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
595495005486	probable active site [active]
595495005487	flavodoxin; Provisional; Region: PRK08105
595495005488	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495005489	D-galactonate transporter; Region: 2A0114; TIGR00893
595495005490	putative substrate translocation pore; other site
595495005491	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
595495005492	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
595495005493	active site
595495005494	tetramer interface [polypeptide binding]; other site
595495005495	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
595495005496	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
595495005497	active site
595495005498	tetramer interface [polypeptide binding]; other site
595495005499	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
595495005500	TRAM domain; Region: TRAM; pfam01938
595495005501	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495005502	S-adenosylmethionine binding site [chemical binding]; other site
595495005503	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
595495005504	HD domain; Region: HD_4; pfam13328
595495005505	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
595495005506	synthetase active site [active]
595495005507	NTP binding site [chemical binding]; other site
595495005508	metal binding site [ion binding]; metal-binding site
595495005509	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
595495005510	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
595495005511	antitoxin MazE; Provisional; Region: PRK09798
595495005512	toxin MazF; Provisional; Region: PRK09907
595495005513	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
595495005514	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
595495005515	homodimer interface [polypeptide binding]; other site
595495005516	metal binding site [ion binding]; metal-binding site
595495005517	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
595495005518	homodimer interface [polypeptide binding]; other site
595495005519	active site
595495005520	putative chemical substrate binding site [chemical binding]; other site
595495005521	metal binding site [ion binding]; metal-binding site
595495005522	CTP synthetase; Validated; Region: pyrG; PRK05380
595495005523	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
595495005524	Catalytic site [active]
595495005525	active site
595495005526	UTP binding site [chemical binding]; other site
595495005527	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
595495005528	active site
595495005529	putative oxyanion hole; other site
595495005530	catalytic triad [active]
595495005531	enolase; Provisional; Region: eno; PRK00077
595495005532	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
595495005533	dimer interface [polypeptide binding]; other site
595495005534	metal binding site [ion binding]; metal-binding site
595495005535	substrate binding pocket [chemical binding]; other site
595495005536	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
595495005537	Repair protein; Region: Repair_PSII; pfam04536
595495005538	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
595495005539	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
595495005540	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
595495005541	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
595495005542	nucleotide binding site [chemical binding]; other site
595495005543	Major Facilitator Superfamily; Region: MFS_1; pfam07690
595495005544	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495005545	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK06935
595495005546	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
595495005547	NADP binding site [chemical binding]; other site
595495005548	homodimer interface [polypeptide binding]; other site
595495005549	active site
595495005550	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
595495005551	FAD binding domain; Region: FAD_binding_4; pfam01565
595495005552	benzoate transport; Region: 2A0115; TIGR00895
595495005553	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495005554	putative substrate translocation pore; other site
595495005555	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
595495005556	Ligand binding site [chemical binding]; other site
595495005557	Electron transfer flavoprotein domain; Region: ETF; pfam01012
595495005558	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
595495005559	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
595495005560	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
595495005561	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
595495005562	Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]; Region: GlpP; COG1954
595495005563	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
595495005564	putative oxidoreductase FixC; Provisional; Region: PRK10157
595495005565	6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a...; Region: PTPS; cd00470
595495005566	homohexamer interface [polypeptide binding]; other site
595495005567	putative substrate stabilizing pore; other site
595495005568	pterin binding site; other site
595495005569	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
595495005570	Flavodoxin; Region: Flavodoxin_1; pfam00258
595495005571	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
595495005572	FAD binding pocket [chemical binding]; other site
595495005573	FAD binding motif [chemical binding]; other site
595495005574	catalytic residues [active]
595495005575	NAD binding pocket [chemical binding]; other site
595495005576	phosphate binding motif [ion binding]; other site
595495005577	beta-alpha-beta structure motif; other site
595495005578	sulfite reductase subunit beta; Provisional; Region: PRK13504
595495005579	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
595495005580	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
595495005581	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
595495005582	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
595495005583	Active Sites [active]
595495005584	Hok/gef family; Region: HOK_GEF; pfam01848
595495005585	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
595495005586	CRISPR-associated helicase Cas3 [Defense mechanisms]; Region: COG1203
595495005587	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
595495005588	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669
595495005589	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cl09719
595495005590	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-E; cd09646
595495005591	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
595495005592	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
595495005593	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09664
595495005594	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-E; cd09719
595495005595	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I-E; cd09648
595495005596	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
595495005597	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
595495005598	metal binding site [ion binding]; metal-binding site
595495005599	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
595495005600	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
595495005601	Active Sites [active]
595495005602	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
595495005603	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
595495005604	CysD dimerization site [polypeptide binding]; other site
595495005605	G1 box; other site
595495005606	putative GEF interaction site [polypeptide binding]; other site
595495005607	GTP/Mg2+ binding site [chemical binding]; other site
595495005608	Switch I region; other site
595495005609	G2 box; other site
595495005610	G3 box; other site
595495005611	Switch II region; other site
595495005612	G4 box; other site
595495005613	G5 box; other site
595495005614	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
595495005615	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
595495005616	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
595495005617	ligand-binding site [chemical binding]; other site
595495005618	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
595495005619	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
595495005620	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
595495005621	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
595495005622	substrate binding site; other site
595495005623	dimer interface; other site
595495005624	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
595495005625	homotrimer interaction site [polypeptide binding]; other site
595495005626	zinc binding site [ion binding]; other site
595495005627	CDP-binding sites; other site
595495005628	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
595495005629	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
595495005630	Permutation of conserved domain; other site
595495005631	active site
595495005632	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
595495005633	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
595495005634	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
595495005635	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495005636	S-adenosylmethionine binding site [chemical binding]; other site
595495005637	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
595495005638	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
595495005639	Peptidase family M23; Region: Peptidase_M23; pfam01551
595495005640	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
595495005641	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
595495005642	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
595495005643	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
595495005644	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
595495005645	DNA binding residues [nucleotide binding]
595495005646	MarR family; Region: MarR_2; cl17246
595495005647	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
595495005648	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
595495005649	Flavoprotein; Region: Flavoprotein; pfam02441
595495005650	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
595495005651	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
595495005652	putative transporter; Provisional; Region: PRK09821
595495005653	GntP family permease; Region: GntP_permease; pfam02447
595495005654	hypothetical protein; Provisional; Region: PRK09989
595495005655	putative aldolase; Validated; Region: PRK08130
595495005656	active site
595495005657	intersubunit interface [polypeptide binding]; other site
595495005658	Zn2+ binding site [ion binding]; other site
595495005659	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
595495005660	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
595495005661	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
595495005662	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
595495005663	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
595495005664	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
595495005665	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
595495005666	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
595495005667	active site
595495005668	metal binding site [ion binding]; metal-binding site
595495005669	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
595495005670	MutS domain I; Region: MutS_I; pfam01624
595495005671	MutS domain II; Region: MutS_II; pfam05188
595495005672	MutS domain III; Region: MutS_III; pfam05192
595495005673	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
595495005674	Walker A/P-loop; other site
595495005675	ATP binding site [chemical binding]; other site
595495005676	Q-loop/lid; other site
595495005677	ABC transporter signature motif; other site
595495005678	Walker B; other site
595495005679	D-loop; other site
595495005680	H-loop/switch region; other site
595495005681	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
595495005682	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
595495005683	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
595495005684	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
595495005685	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495005686	Walker A motif; other site
595495005687	ATP binding site [chemical binding]; other site
595495005688	Walker B motif; other site
595495005689	arginine finger; other site
595495005690	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
595495005691	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
595495005692	dimerization interface [polypeptide binding]; other site
595495005693	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
595495005694	ATP binding site [chemical binding]; other site
595495005695	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
595495005696	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
595495005697	hydrogenase assembly chaperone; Provisional; Region: PRK10409
595495005698	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
595495005699	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
595495005700	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
595495005701	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
595495005702	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
595495005703	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
595495005704	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
595495005705	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
595495005706	NADH dehydrogenase; Region: NADHdh; cl00469
595495005707	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
595495005708	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
595495005709	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
595495005710	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
595495005711	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
595495005712	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
595495005713	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
595495005714	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
595495005715	nickel binding site [ion binding]; other site
595495005716	cryptic 6-phospho-beta-glucosidase; Provisional; Region: PRK09852
595495005717	beta-galactosidase; Region: BGL; TIGR03356
595495005718	PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional; Region: PRK09796
595495005719	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
595495005720	active site turn [active]
595495005721	phosphorylation site [posttranslational modification]
595495005722	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
595495005723	Transcriptional regulators [Transcription]; Region: PurR; COG1609
595495005724	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
595495005725	DNA binding site [nucleotide binding]
595495005726	domain linker motif; other site
595495005727	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
595495005728	dimerization interface (closed form) [polypeptide binding]; other site
595495005729	ligand binding site [chemical binding]; other site
595495005730	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495005731	4Fe-4S binding domain; Region: Fer4; cl02805
595495005732	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
595495005733	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
595495005734	Acylphosphatase; Region: Acylphosphatase; pfam00708
595495005735	HypF finger; Region: zf-HYPF; pfam07503
595495005736	HypF finger; Region: zf-HYPF; pfam07503
595495005737	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
595495005738	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
595495005739	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
595495005740	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
595495005741	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
595495005742	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
595495005743	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
595495005744	iron binding site [ion binding]; other site
595495005745	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
595495005746	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
595495005747	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495005748	Walker A motif; other site
595495005749	ATP binding site [chemical binding]; other site
595495005750	Walker B motif; other site
595495005751	arginine finger; other site
595495005752	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
595495005753	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
595495005754	putative active site [active]
595495005755	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
595495005756	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
595495005757	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
595495005758	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
595495005759	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
595495005760	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
595495005761	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
595495005762	putative NAD(P) binding site [chemical binding]; other site
595495005763	active site
595495005764	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
595495005765	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
595495005766	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
595495005767	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
595495005768	PTS system, glucitol/sorbitol-specific, IIC component; Region: EII-GUT; TIGR00821
595495005769	Transglycosylase SLT domain; Region: SLT_2; pfam13406
595495005770	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
595495005771	N-acetyl-D-glucosamine binding site [chemical binding]; other site
595495005772	hypothetical protein; Validated; Region: PRK03661
595495005773	recombinase A; Provisional; Region: recA; PRK09354
595495005774	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
595495005775	hexamer interface [polypeptide binding]; other site
595495005776	Walker A motif; other site
595495005777	ATP binding site [chemical binding]; other site
595495005778	Walker B motif; other site
595495005779	recombination regulator RecX; Reviewed; Region: recX; PRK00117
595495005780	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
595495005781	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
595495005782	motif 1; other site
595495005783	active site
595495005784	motif 2; other site
595495005785	motif 3; other site
595495005786	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
595495005787	DHHA1 domain; Region: DHHA1; pfam02272
595495005788	carbon storage regulator; Provisional; Region: PRK01712
595495005789	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
595495005790	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495005791	motif II; other site
595495005792	Predicted membrane protein [Function unknown]; Region: COG1238
595495005793	glutamate--cysteine ligase; Provisional; Region: PRK02107
595495005794	S-ribosylhomocysteinase; Provisional; Region: PRK02260
595495005795	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
595495005796	Zn2+ binding site [ion binding]; other site
595495005797	Mg2+ binding site [ion binding]; other site
595495005798	AAA domain; Region: AAA_33; pfam13671
595495005799	RNA ligase; Region: RNA_ligase; pfam09414
595495005800	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
595495005801	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495005802	putative substrate translocation pore; other site
595495005803	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495005804	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
595495005805	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
595495005806	HlyD family secretion protein; Region: HlyD_3; pfam13437
595495005807	transcriptional repressor MprA; Provisional; Region: PRK10870
595495005808	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
595495005809	putative L-valine exporter; Provisional; Region: PRK10408
595495005810	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
595495005811	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
595495005812	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495005813	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
595495005814	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
595495005815	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
595495005816	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495005817	dimer interface [polypeptide binding]; other site
595495005818	conserved gate region; other site
595495005819	putative PBP binding loops; other site
595495005820	ABC-ATPase subunit interface; other site
595495005821	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
595495005822	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
595495005823	Walker A/P-loop; other site
595495005824	ATP binding site [chemical binding]; other site
595495005825	Q-loop/lid; other site
595495005826	ABC transporter signature motif; other site
595495005827	Walker B; other site
595495005828	D-loop; other site
595495005829	H-loop/switch region; other site
595495005830	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
595495005831	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
595495005832	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
595495005833	dimer interface [polypeptide binding]; other site
595495005834	putative radical transfer pathway; other site
595495005835	diiron center [ion binding]; other site
595495005836	tyrosyl radical; other site
595495005837	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
595495005838	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
595495005839	Class I ribonucleotide reductase; Region: RNR_I; cd01679
595495005840	active site
595495005841	dimer interface [polypeptide binding]; other site
595495005842	catalytic residues [active]
595495005843	effector binding site; other site
595495005844	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495005845	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
595495005846	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
595495005847	catalytic residues [active]
595495005848	hypothetical protein; Provisional; Region: PRK10132
595495005849	hypothetical protein; Provisional; Region: PRK10556
595495005850	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
595495005851	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
595495005852	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
595495005853	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YgaP, and similar uncharacterized putative rhodanese-related sulfurtransferases; Region: RHOD_YgaP; cd01527
595495005854	active site residue [active]
595495005855	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
595495005856	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
595495005857	dimerization interface [polypeptide binding]; other site
595495005858	putative DNA binding site [nucleotide binding]; other site
595495005859	Transcriptional regulators [Transcription]; Region: MarR; COG1846
595495005860	putative Zn2+ binding site [ion binding]; other site
595495005861	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
595495005862	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
595495005863	bacterial OsmY and nodulation domain; Region: BON; smart00749
595495005864	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
595495005865	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
595495005866	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
595495005867	DNA-binding site [nucleotide binding]; DNA binding site
595495005868	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
595495005869	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
595495005870	4-aminobutyrate aminotransferase; Validated; Region: PRK08088
595495005871	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
595495005872	inhibitor-cofactor binding pocket; inhibition site
595495005873	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495005874	catalytic residue [active]
595495005875	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
595495005876	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
595495005877	tetramerization interface [polypeptide binding]; other site
595495005878	NAD(P) binding site [chemical binding]; other site
595495005879	catalytic residues [active]
595495005880	Predicted dehydrogenase [General function prediction only]; Region: COG0579
595495005881	hydroxyglutarate oxidase; Provisional; Region: PRK11728
595495005882	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
595495005883	substrate binding pocket [chemical binding]; other site
595495005884	active site
595495005885	iron coordination sites [ion binding]; other site
595495005886	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
595495005887	active site
595495005888	catalytic site [active]
595495005889	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
595495005890	Transposase; Region: HTH_Tnp_1; cl17663
595495005891	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
595495005892	putative transposase OrfB; Reviewed; Region: PHA02517
595495005893	HTH-like domain; Region: HTH_21; pfam13276
595495005894	Integrase core domain; Region: rve; pfam00665
595495005895	Integrase core domain; Region: rve_2; pfam13333
595495005896	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
595495005897	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495005898	ATP binding site [chemical binding]; other site
595495005899	Mg2+ binding site [ion binding]; other site
595495005900	G-X-G motif; other site
595495005901	integrase; Provisional; Region: PRK09692
595495005902	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
595495005903	active site
595495005904	Int/Topo IB signature motif; other site
595495005905	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
595495005906	SmpB-tmRNA interface; other site
595495005907	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
595495005908	putative coenzyme Q binding site [chemical binding]; other site
595495005909	hypothetical protein; Validated; Region: PRK01777
595495005910	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
595495005911	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
595495005912	recombination and repair protein; Provisional; Region: PRK10869
595495005913	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
595495005914	Walker A/P-loop; other site
595495005915	ATP binding site [chemical binding]; other site
595495005916	Q-loop/lid; other site
595495005917	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
595495005918	Q-loop/lid; other site
595495005919	ABC transporter signature motif; other site
595495005920	Walker B; other site
595495005921	D-loop; other site
595495005922	H-loop/switch region; other site
595495005923	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
595495005924	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
595495005925	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
595495005926	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
595495005927	dimer interface [polypeptide binding]; other site
595495005928	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
595495005929	hypothetical protein; Provisional; Region: PRK11573
595495005930	Domain of unknown function DUF21; Region: DUF21; pfam01595
595495005931	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
595495005932	Transporter associated domain; Region: CorC_HlyC; smart01091
595495005933	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
595495005934	signal recognition particle protein; Provisional; Region: PRK10867
595495005935	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
595495005936	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
595495005937	P loop; other site
595495005938	GTP binding site [chemical binding]; other site
595495005939	Signal peptide binding domain; Region: SRP_SPB; pfam02978
595495005940	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
595495005941	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
595495005942	RimM N-terminal domain; Region: RimM; pfam01782
595495005943	PRC-barrel domain; Region: PRC; pfam05239
595495005944	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
595495005945	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
595495005946	putative outer membrane lipoprotein; Provisional; Region: PRK09967
595495005947	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
595495005948	ligand binding site [chemical binding]; other site
595495005949	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
595495005950	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
595495005951	metal binding site [ion binding]; metal-binding site
595495005952	active site
595495005953	I-site; other site
595495005954	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
595495005955	lipoprotein; Provisional; Region: PRK11443
595495005956	Protein of unknown function (DUF2799); Region: DUF2799; pfam10973
595495005957	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
595495005958	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
595495005959	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
595495005960	chorismate mutase domain of T-protein; Region: CM_T; TIGR01799
595495005961	prephenate dehydrogenase; Validated; Region: PRK08507
595495005962	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
595495005963	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
595495005964	Prephenate dehydratase; Region: PDT; pfam00800
595495005965	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
595495005966	putative L-Phe binding site [chemical binding]; other site
595495005967	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
595495005968	30S subunit binding site; other site
595495005969	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
595495005970	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
595495005971	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
595495005972	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
595495005973	RNA binding surface [nucleotide binding]; other site
595495005974	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
595495005975	active site
595495005976	hypothetical protein; Provisional; Region: PRK10723
595495005977	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
595495005978	protein disaggregation chaperone; Provisional; Region: PRK10865
595495005979	Clp amino terminal domain; Region: Clp_N; pfam02861
595495005980	Clp amino terminal domain; Region: Clp_N; pfam02861
595495005981	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495005982	Walker A motif; other site
595495005983	ATP binding site [chemical binding]; other site
595495005984	Walker B motif; other site
595495005985	arginine finger; other site
595495005986	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495005987	Walker A motif; other site
595495005988	ATP binding site [chemical binding]; other site
595495005989	Walker B motif; other site
595495005990	arginine finger; other site
595495005991	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
595495005992	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
595495005993	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495005994	putative substrate translocation pore; other site
595495005995	lipoprotein; Provisional; Region: PRK10759
595495005996	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
595495005997	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
595495005998	domain interface [polypeptide binding]; other site
595495005999	putative active site [active]
595495006000	catalytic site [active]
595495006001	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
595495006002	domain interface [polypeptide binding]; other site
595495006003	putative active site [active]
595495006004	catalytic site [active]
595495006005	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
595495006006	CoA binding domain; Region: CoA_binding_2; pfam13380
595495006007	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
595495006008	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
595495006009	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
595495006010	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
595495006011	Uncharacterized conserved protein [Function unknown]; Region: COG3148
595495006012	thioredoxin 2; Provisional; Region: PRK10996
595495006013	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
595495006014	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
595495006015	catalytic residues [active]
595495006016	putative methyltransferase; Provisional; Region: PRK10864
595495006017	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
595495006018	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
595495006019	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
595495006020	ligand binding site [chemical binding]; other site
595495006021	active site
595495006022	UGI interface [polypeptide binding]; other site
595495006023	catalytic site [active]
595495006024	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
595495006025	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
595495006026	Transcriptional regulator [Transcription]; Region: LysR; COG0583
595495006027	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495006028	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
595495006029	dimerization interface [polypeptide binding]; other site
595495006030	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
595495006031	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
595495006032	ATP binding site [chemical binding]; other site
595495006033	Mg++ binding site [ion binding]; other site
595495006034	motif III; other site
595495006035	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
595495006036	nucleotide binding region [chemical binding]; other site
595495006037	ATP-binding site [chemical binding]; other site
595495006038	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
595495006039	Methyltransferase domain; Region: Methyltransf_26; pfam13659
595495006040	L-aspartate oxidase; Provisional; Region: PRK09077
595495006041	L-aspartate oxidase; Provisional; Region: PRK06175
595495006042	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
595495006043	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
595495006044	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
595495006045	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
595495006046	DNA binding residues [nucleotide binding]
595495006047	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
595495006048	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
595495006049	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
595495006050	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
595495006051	anti-sigma E factor; Provisional; Region: rseB; PRK09455
595495006052	SoxR reducing system protein RseC; Provisional; Region: PRK10862
595495006053	GTP-binding protein LepA; Provisional; Region: PRK05433
595495006054	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
595495006055	G1 box; other site
595495006056	putative GEF interaction site [polypeptide binding]; other site
595495006057	GTP/Mg2+ binding site [chemical binding]; other site
595495006058	Switch I region; other site
595495006059	G2 box; other site
595495006060	G3 box; other site
595495006061	Switch II region; other site
595495006062	G4 box; other site
595495006063	G5 box; other site
595495006064	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
595495006065	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
595495006066	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
595495006067	signal peptidase I; Provisional; Region: PRK10861
595495006068	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
595495006069	Catalytic site [active]
595495006070	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
595495006071	ribonuclease III; Reviewed; Region: rnc; PRK00102
595495006072	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
595495006073	dimerization interface [polypeptide binding]; other site
595495006074	active site
595495006075	metal binding site [ion binding]; metal-binding site
595495006076	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
595495006077	dsRNA binding site [nucleotide binding]; other site
595495006078	GTPase Era; Reviewed; Region: era; PRK00089
595495006079	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
595495006080	G1 box; other site
595495006081	GTP/Mg2+ binding site [chemical binding]; other site
595495006082	Switch I region; other site
595495006083	G2 box; other site
595495006084	Switch II region; other site
595495006085	G3 box; other site
595495006086	G4 box; other site
595495006087	G5 box; other site
595495006088	KH domain; Region: KH_2; pfam07650
595495006089	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
595495006090	Recombination protein O N terminal; Region: RecO_N; pfam11967
595495006091	Recombination protein O C terminal; Region: RecO_C; pfam02565
595495006092	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
595495006093	active site
595495006094	hydrophilic channel; other site
595495006095	dimerization interface [polypeptide binding]; other site
595495006096	catalytic residues [active]
595495006097	active site lid [active]
595495006098	holo-[acyl-carrier-protein] synthase; Region: acpS; TIGR00516
595495006099	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
595495006100	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
595495006101	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
595495006102	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
595495006103	putative active site [active]
595495006104	hypothetical protein; Provisional; Region: PRK11590
595495006105	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
595495006106	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
595495006107	nucleoside/Zn binding site; other site
595495006108	dimer interface [polypeptide binding]; other site
595495006109	catalytic motif [active]
595495006110	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
595495006111	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
595495006112	substrate binding pocket [chemical binding]; other site
595495006113	membrane-bound complex binding site; other site
595495006114	hinge residues; other site
595495006115	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
595495006116	N-acetyl-D-glucosamine binding site [chemical binding]; other site
595495006117	catalytic residue [active]
595495006118	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
595495006119	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
595495006120	dimerization interface [polypeptide binding]; other site
595495006121	ATP binding site [chemical binding]; other site
595495006122	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
595495006123	dimerization interface [polypeptide binding]; other site
595495006124	ATP binding site [chemical binding]; other site
595495006125	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
595495006126	putative active site [active]
595495006127	catalytic triad [active]
595495006128	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
595495006129	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
595495006130	dimer interface [polypeptide binding]; other site
595495006131	phosphorylation site [posttranslational modification]
595495006132	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495006133	ATP binding site [chemical binding]; other site
595495006134	Mg2+ binding site [ion binding]; other site
595495006135	G-X-G motif; other site
595495006136	hypothetical protein; Provisional; Region: PRK10722
595495006137	response regulator GlrR; Provisional; Region: PRK15115
595495006138	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495006139	active site
595495006140	phosphorylation site [posttranslational modification]
595495006141	intermolecular recognition site; other site
595495006142	dimerization interface [polypeptide binding]; other site
595495006143	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495006144	Walker A motif; other site
595495006145	ATP binding site [chemical binding]; other site
595495006146	Walker B motif; other site
595495006147	arginine finger; other site
595495006148	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
595495006149	Nitrogen regulatory protein P-II; Region: P-II; smart00938
595495006150	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
595495006151	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
595495006152	heme-binding site [chemical binding]; other site
595495006153	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
595495006154	FAD binding pocket [chemical binding]; other site
595495006155	FAD binding motif [chemical binding]; other site
595495006156	phosphate binding motif [ion binding]; other site
595495006157	beta-alpha-beta structure motif; other site
595495006158	NAD binding pocket [chemical binding]; other site
595495006159	Heme binding  pocket [chemical binding]; other site
595495006160	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
595495006161	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
595495006162	dimer interface [polypeptide binding]; other site
595495006163	active site
595495006164	glycine-pyridoxal phosphate binding site [chemical binding]; other site
595495006165	folate binding site [chemical binding]; other site
595495006166	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
595495006167	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
595495006168	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
595495006169	nucleotide binding site [chemical binding]; other site
595495006170	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
595495006171	TPR motif; other site
595495006172	Tetratricopeptide repeat; Region: TPR_16; pfam13432
595495006173	binding surface
595495006174	TPR repeat; Region: TPR_11; pfam13414
595495006175	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
595495006176	TPR motif; other site
595495006177	binding surface
595495006178	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
595495006179	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
595495006180	ligand binding site [chemical binding]; other site
595495006181	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
595495006182	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
595495006183	Walker A/P-loop; other site
595495006184	ATP binding site [chemical binding]; other site
595495006185	Q-loop/lid; other site
595495006186	ABC transporter signature motif; other site
595495006187	Walker B; other site
595495006188	D-loop; other site
595495006189	H-loop/switch region; other site
595495006190	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
595495006191	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
595495006192	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
595495006193	TM-ABC transporter signature motif; other site
595495006194	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
595495006195	L-threonine dehydrogenase (TDH)-like; Region: THR_DH_like; cd08239
595495006196	putative NAD(P) binding site [chemical binding]; other site
595495006197	catalytic Zn binding site [ion binding]; other site
595495006198	aldose 1-epimerase, similar to Escherichia coli YphB; Region: Aldose_epim_Ec_YphB; cd09021
595495006199	active site
595495006200	catalytic residues [active]
595495006201	Predicted membrane protein [Function unknown]; Region: COG2259
595495006202	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
595495006203	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase; Provisional; Region: PRK06200
595495006204	cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase (BphB)-like, classical (c) SDRs; Region: BphB-like_SDR_c; cd05348
595495006205	NAD binding site [chemical binding]; other site
595495006206	active site
595495006207	Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528
595495006208	[2Fe-2S] cluster binding site [ion binding]; other site
595495006209	Ring hydroxylating dioxygenase beta subunit. This subunit has a similar structure to NTF-2, Ketosteroid isomerase and scytalone dehydratase.The degradation of aromatic compounds by aerobic bacteria frequently begins with the dihydroxylation of the...; Region: ring_hydroxylating_dioxygenases_beta; cd00667
595495006210	inter-subunit interface; other site
595495006211	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
595495006212	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
595495006213	iron-sulfur cluster [ion binding]; other site
595495006214	[2Fe-2S] cluster binding site [ion binding]; other site
595495006215	C-terminal catalytic domain of the oxygenase alpha subunit of naphthalene 1,2-dioxygenase (NDO) and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_NDO-like; cd08881
595495006216	beta subunit interface [polypeptide binding]; other site
595495006217	alpha subunit interface [polypeptide binding]; other site
595495006218	active site
595495006219	substrate binding site [chemical binding]; other site
595495006220	Fe binding site [ion binding]; other site
595495006221	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
595495006222	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495006223	The C-terminal substrate binding domain of LysR-type transcriptional regulator HcaR in involved in 3-phenylpropionic acid catabolism, contains the type2 periplasmic binding fold; Region: PBP2_HcaR; cd08450
595495006224	putative dimerization interface [polypeptide binding]; other site
595495006225	putative substrate binding pocket [chemical binding]; other site
595495006226	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
595495006227	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495006228	putative substrate translocation pore; other site
595495006229	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
595495006230	PRD domain; Region: PRD; pfam00874
595495006231	PRD domain; Region: PRD; pfam00874
595495006232	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
595495006233	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
595495006234	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
595495006235	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
595495006236	active site
595495006237	dimerization interface [polypeptide binding]; other site
595495006238	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
595495006239	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
595495006240	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
595495006241	Rrf2 family protein; Region: rrf2_super; TIGR00738
595495006242	cysteine desulfurase; Provisional; Region: PRK14012
595495006243	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
595495006244	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
595495006245	catalytic residue [active]
595495006246	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
595495006247	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
595495006248	trimerization site [polypeptide binding]; other site
595495006249	active site
595495006250	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
595495006251	co-chaperone HscB; Provisional; Region: hscB; PRK05014
595495006252	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
595495006253	HSP70 interaction site [polypeptide binding]; other site
595495006254	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
595495006255	chaperone protein HscA; Provisional; Region: hscA; PRK05183
595495006256	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
595495006257	nucleotide binding site [chemical binding]; other site
595495006258	putative NEF/HSP70 interaction site [polypeptide binding]; other site
595495006259	SBD interface [polypeptide binding]; other site
595495006260	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
595495006261	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
595495006262	catalytic loop [active]
595495006263	iron binding site [ion binding]; other site
595495006264	hypothetical protein; Provisional; Region: PRK10721
595495006265	aminopeptidase B; Provisional; Region: PRK05015
595495006266	Peptidase; Region: DUF3663; pfam12404
595495006267	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
595495006268	interface (dimer of trimers) [polypeptide binding]; other site
595495006269	Substrate-binding/catalytic site; other site
595495006270	Zn-binding sites [ion binding]; other site
595495006271	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
595495006272	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
595495006273	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
595495006274	active site residue [active]
595495006275	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
595495006276	active site residue [active]
595495006277	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
595495006278	MG2 domain; Region: A2M_N; pfam01835
595495006279	Alpha-2-macroglobulin family; Region: A2M; pfam00207
595495006280	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
595495006281	surface patch; other site
595495006282	thioester region; other site
595495006283	specificity defining residues; other site
595495006284	penicillin-binding protein 1C; Provisional; Region: PRK11240
595495006285	Transglycosylase; Region: Transgly; pfam00912
595495006286	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
595495006287	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
595495006288	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
595495006289	active site
595495006290	multimer interface [polypeptide binding]; other site
595495006291	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
595495006292	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495006293	FeS/SAM binding site; other site
595495006294	cytoskeletal protein RodZ; Provisional; Region: PRK10856
595495006295	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
595495006296	non-specific DNA binding site [nucleotide binding]; other site
595495006297	salt bridge; other site
595495006298	sequence-specific DNA binding site [nucleotide binding]; other site
595495006299	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
595495006300	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
595495006301	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
595495006302	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
595495006303	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
595495006304	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
595495006305	dimer interface [polypeptide binding]; other site
595495006306	motif 1; other site
595495006307	active site
595495006308	motif 2; other site
595495006309	motif 3; other site
595495006310	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
595495006311	anticodon binding site; other site
595495006312	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
595495006313	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
595495006314	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cd00216
595495006315	Trp docking motif [polypeptide binding]; other site
595495006316	active site
595495006317	GTP-binding protein Der; Reviewed; Region: PRK00093
595495006318	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
595495006319	G1 box; other site
595495006320	GTP/Mg2+ binding site [chemical binding]; other site
595495006321	Switch I region; other site
595495006322	G2 box; other site
595495006323	Switch II region; other site
595495006324	G3 box; other site
595495006325	G4 box; other site
595495006326	G5 box; other site
595495006327	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
595495006328	G1 box; other site
595495006329	GTP/Mg2+ binding site [chemical binding]; other site
595495006330	Switch I region; other site
595495006331	G2 box; other site
595495006332	G3 box; other site
595495006333	Switch II region; other site
595495006334	G4 box; other site
595495006335	G5 box; other site
595495006336	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
595495006337	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
595495006338	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
595495006339	generic binding surface II; other site
595495006340	generic binding surface I; other site
595495006341	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
595495006342	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
595495006343	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
595495006344	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
595495006345	active site
595495006346	GMP synthase; Reviewed; Region: guaA; PRK00074
595495006347	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
595495006348	AMP/PPi binding site [chemical binding]; other site
595495006349	candidate oxyanion hole; other site
595495006350	catalytic triad [active]
595495006351	potential glutamine specificity residues [chemical binding]; other site
595495006352	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
595495006353	ATP Binding subdomain [chemical binding]; other site
595495006354	Ligand Binding sites [chemical binding]; other site
595495006355	Dimerization subdomain; other site
595495006356	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
595495006357	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
595495006358	MASE1; Region: MASE1; pfam05231
595495006359	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
595495006360	diguanylate cyclase; Region: GGDEF; smart00267
595495006361	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
595495006362	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495006363	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
595495006364	exopolyphosphatase; Provisional; Region: PRK10854
595495006365	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
595495006366	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
595495006367	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
595495006368	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
595495006369	Catalytic C-terminal domain, first repeat, of prokaryotic polyphosphate kinase 1 and similar proteins; Region: PLDc_PPK1_C1; cd09114
595495006370	domain interface [polypeptide binding]; other site
595495006371	active site
595495006372	catalytic site [active]
595495006373	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
595495006374	putative active site [active]
595495006375	catalytic site [active]
595495006376	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
595495006377	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
595495006378	active site
595495006379	substrate binding site [chemical binding]; other site
595495006380	cosubstrate binding site; other site
595495006381	catalytic site [active]
595495006382	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
595495006383	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
595495006384	dimerization interface [polypeptide binding]; other site
595495006385	putative ATP binding site [chemical binding]; other site
595495006386	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
595495006387	active site
595495006388	uracil transporter; Provisional; Region: PRK10720
595495006389	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
595495006390	DNA replication initiation factor; Provisional; Region: PRK08084
595495006391	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
595495006392	ArsC family; Region: ArsC; pfam03960
595495006393	catalytic residues [active]
595495006394	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
595495006395	Peptidase family M48; Region: Peptidase_M48; cl12018
595495006396	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
595495006397	Domain of unknown function DUF20; Region: UPF0118; pfam01594
595495006398	putative formate transporter; Provisional; Region: focB; PRK09713
595495006399	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains [Transcription / Signal transduction mechanisms]; Region: FhlA; COG3604
595495006400	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
595495006401	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495006402	Walker A motif; other site
595495006403	ATP binding site [chemical binding]; other site
595495006404	Walker B motif; other site
595495006405	arginine finger; other site
595495006406	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
595495006407	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
595495006408	hydrogenase 4 subunit H; Validated; Region: PRK08222
595495006409	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
595495006410	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
595495006411	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
595495006412	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
595495006413	hydrogenase 4 subunit F; Validated; Region: PRK06458
595495006414	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
595495006415	hydrogenase 4 membrane subunit; Provisional; Region: hyfE; PRK11492
595495006416	hydrogenase 4 subunit D; Validated; Region: PRK06525
595495006417	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
595495006418	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
595495006419	NADH dehydrogenase; Region: NADHdh; cl00469
595495006420	hydrogenase 4 subunit B; Validated; Region: PRK06521
595495006421	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
595495006422	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
595495006423	4Fe-4S binding domain; Region: Fer4; pfam00037
595495006424	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
595495006425	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
595495006426	catalytic triad [active]
595495006427	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
595495006428	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
595495006429	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
595495006430	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
595495006431	dihydrodipicolinate synthase; Region: dapA; TIGR00674
595495006432	dimer interface [polypeptide binding]; other site
595495006433	active site
595495006434	catalytic residue [active]
595495006435	lipoprotein; Provisional; Region: PRK11679
595495006436	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
595495006437	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
595495006438	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
595495006439	ATP binding site [chemical binding]; other site
595495006440	active site
595495006441	substrate binding site [chemical binding]; other site
595495006442	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
595495006443	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
595495006444	oligomeric interface; other site
595495006445	putative active site [active]
595495006446	homodimer interface [polypeptide binding]; other site
595495006447	Predicted metalloprotease [General function prediction only]; Region: COG2321
595495006448	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
595495006449	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
595495006450	Helicase; Region: Helicase_RecD; pfam05127
595495006451	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
595495006452	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
595495006453	putative hydrolase; Provisional; Region: PRK11460
595495006454	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
595495006455	hypothetical protein; Provisional; Region: PRK13664
595495006456	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
595495006457	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
595495006458	metal binding site [ion binding]; metal-binding site
595495006459	dimer interface [polypeptide binding]; other site
595495006460	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
595495006461	ArsC family; Region: ArsC; pfam03960
595495006462	putative catalytic residues [active]
595495006463	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
595495006464	Protein export membrane protein; Region: SecD_SecF; cl14618
595495006465	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
595495006466	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
595495006467	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
595495006468	dimerization interface [polypeptide binding]; other site
595495006469	Histidine kinase; Region: HisKA_3; pfam07730
595495006470	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495006471	ATP binding site [chemical binding]; other site
595495006472	Mg2+ binding site [ion binding]; other site
595495006473	G-X-G motif; other site
595495006474	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
595495006475	4Fe-4S binding domain; Region: Fer4; pfam00037
595495006476	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
595495006477	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
595495006478	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
595495006479	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
595495006480	dimer interface [polypeptide binding]; other site
595495006481	ADP-ribose binding site [chemical binding]; other site
595495006482	active site
595495006483	nudix motif; other site
595495006484	metal binding site [ion binding]; metal-binding site
595495006485	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
595495006486	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
595495006487	transketolase; Reviewed; Region: PRK12753
595495006488	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
595495006489	TPP-binding site [chemical binding]; other site
595495006490	dimer interface [polypeptide binding]; other site
595495006491	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
595495006492	PYR/PP interface [polypeptide binding]; other site
595495006493	dimer interface [polypeptide binding]; other site
595495006494	TPP binding site [chemical binding]; other site
595495006495	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
595495006496	transaldolase-like protein; Provisional; Region: PTZ00411
595495006497	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
595495006498	active site
595495006499	dimer interface [polypeptide binding]; other site
595495006500	catalytic residue [active]
595495006501	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
595495006502	Malic enzyme, N-terminal domain; Region: malic; pfam00390
595495006503	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
595495006504	putative NAD(P) binding site [chemical binding]; other site
595495006505	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
595495006506	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
595495006507	putative hexamer interface [polypeptide binding]; other site
595495006508	putative hexagonal pore; other site
595495006509	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
595495006510	G1 box; other site
595495006511	GTP/Mg2+ binding site [chemical binding]; other site
595495006512	G2 box; other site
595495006513	Switch I region; other site
595495006514	G3 box; other site
595495006515	Switch II region; other site
595495006516	G4 box; other site
595495006517	G5 box; other site
595495006518	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
595495006519	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
595495006520	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
595495006521	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
595495006522	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
595495006523	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
595495006524	Hexamer interface [polypeptide binding]; other site
595495006525	Hexagonal pore residue; other site
595495006526	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
595495006527	Hexamer/Pentamer interface [polypeptide binding]; other site
595495006528	central pore; other site
595495006529	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
595495006530	putative catalytic cysteine [active]
595495006531	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
595495006532	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
595495006533	nucleotide binding site [chemical binding]; other site
595495006534	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
595495006535	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
595495006536	active site
595495006537	metal binding site [ion binding]; metal-binding site
595495006538	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
595495006539	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
595495006540	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
595495006541	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
595495006542	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
595495006543	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
595495006544	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
595495006545	putative hexamer interface [polypeptide binding]; other site
595495006546	putative hexagonal pore; other site
595495006547	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
595495006548	putative hexamer interface [polypeptide binding]; other site
595495006549	putative hexagonal pore; other site
595495006550	carboxysome structural protein EutK; Provisional; Region: PRK15466
595495006551	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
595495006552	Hexamer interface [polypeptide binding]; other site
595495006553	Hexagonal pore residue; other site
595495006554	transcriptional regulator EutR; Provisional; Region: PRK10130
595495006555	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495006556	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495006557	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
595495006558	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
595495006559	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
595495006560	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
595495006561	active site
595495006562	metal binding site [ion binding]; metal-binding site
595495006563	putative acetyltransferase; Provisional; Region: PRK03624
595495006564	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
595495006565	Coenzyme A binding pocket [chemical binding]; other site
595495006566	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
595495006567	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
595495006568	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
595495006569	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
595495006570	putative periplasmic esterase; Provisional; Region: PRK03642
595495006571	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
595495006572	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
595495006573	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
595495006574	active site turn [active]
595495006575	phosphorylation site [posttranslational modification]
595495006576	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
595495006577	N-acetylmuramic acid 6-phosphate etherase; Region: TIGR00274
595495006578	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
595495006579	putative active site [active]
595495006580	transcriptional regulator MurR; Provisional; Region: PRK15482
595495006581	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
595495006582	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
595495006583	putative active site [active]
595495006584	short chain dehydrogenase; Provisional; Region: PRK08226
595495006585	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
595495006586	NAD binding site [chemical binding]; other site
595495006587	homotetramer interface [polypeptide binding]; other site
595495006588	homodimer interface [polypeptide binding]; other site
595495006589	active site
595495006590	thiosulfate transporter subunit; Provisional; Region: PRK10852
595495006591	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
595495006592	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
595495006593	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495006594	dimer interface [polypeptide binding]; other site
595495006595	conserved gate region; other site
595495006596	putative PBP binding loops; other site
595495006597	ABC-ATPase subunit interface; other site
595495006598	sulfate transport protein; Provisional; Region: cysT; CHL00187
595495006599	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495006600	dimer interface [polypeptide binding]; other site
595495006601	conserved gate region; other site
595495006602	putative PBP binding loops; other site
595495006603	ABC-ATPase subunit interface; other site
595495006604	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
595495006605	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
595495006606	Walker A/P-loop; other site
595495006607	ATP binding site [chemical binding]; other site
595495006608	Q-loop/lid; other site
595495006609	ABC transporter signature motif; other site
595495006610	Walker B; other site
595495006611	D-loop; other site
595495006612	H-loop/switch region; other site
595495006613	TOBE-like domain; Region: TOBE_3; pfam12857
595495006614	cysteine synthase B; Region: cysM; TIGR01138
595495006615	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
595495006616	dimer interface [polypeptide binding]; other site
595495006617	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495006618	catalytic residue [active]
595495006619	hypothetical protein; Provisional; Region: PRK10318
595495006620	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
595495006621	dimer interface [polypeptide binding]; other site
595495006622	pyridoxamine kinase; Validated; Region: PRK05756
595495006623	pyridoxal binding site [chemical binding]; other site
595495006624	ATP binding site [chemical binding]; other site
595495006625	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
595495006626	HPr interaction site; other site
595495006627	glycerol kinase (GK) interaction site [polypeptide binding]; other site
595495006628	active site
595495006629	phosphorylation site [posttranslational modification]
595495006630	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
595495006631	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
595495006632	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
595495006633	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
595495006634	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
595495006635	dimerization domain swap beta strand [polypeptide binding]; other site
595495006636	regulatory protein interface [polypeptide binding]; other site
595495006637	active site
595495006638	regulatory phosphorylation site [posttranslational modification]; other site
595495006639	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
595495006640	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
595495006641	dimer interface [polypeptide binding]; other site
595495006642	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495006643	catalytic residue [active]
595495006644	putative sulfate transport protein CysZ; Validated; Region: PRK04949
595495006645	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
595495006646	cell division protein ZipA; Provisional; Region: PRK03427
595495006647	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
595495006648	FtsZ protein binding site [polypeptide binding]; other site
595495006649	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
595495006650	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
595495006651	nucleotide binding pocket [chemical binding]; other site
595495006652	K-X-D-G motif; other site
595495006653	catalytic site [active]
595495006654	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
595495006655	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
595495006656	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
595495006657	Dimer interface [polypeptide binding]; other site
595495006658	BRCT sequence motif; other site
595495006659	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
595495006660	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
595495006661	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
595495006662	Transcriptional regulator [Transcription]; Region: LysR; COG0583
595495006663	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495006664	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
595495006665	putative dimerization interface [polypeptide binding]; other site
595495006666	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
595495006667	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
595495006668	active site
595495006669	HIGH motif; other site
595495006670	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
595495006671	active site
595495006672	KMSKS motif; other site
595495006673	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
595495006674	salt bridge; other site
595495006675	non-specific DNA binding site [nucleotide binding]; other site
595495006676	sequence-specific DNA binding site [nucleotide binding]; other site
595495006677	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
595495006678	MASE1; Region: MASE1; pfam05231
595495006679	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
595495006680	diguanylate cyclase; Region: GGDEF; smart00267
595495006681	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
595495006682	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
595495006683	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
595495006684	Nucleoside recognition; Region: Gate; pfam07670
595495006685	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
595495006686	manganese transport protein MntH; Reviewed; Region: PRK00701
595495006687	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
595495006688	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
595495006689	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
595495006690	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
595495006691	Cl- selectivity filter; other site
595495006692	Cl- binding residues [ion binding]; other site
595495006693	pore gating glutamate residue; other site
595495006694	dimer interface [polypeptide binding]; other site
595495006695	glucokinase, proteobacterial type; Region: glk; TIGR00749
595495006696	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
595495006697	nucleotide binding site [chemical binding]; other site
595495006698	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
595495006699	active site
595495006700	P-loop; other site
595495006701	phosphorylation site [posttranslational modification]
595495006702	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
595495006703	aminopeptidase; Provisional; Region: PRK09795
595495006704	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
595495006705	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
595495006706	active site
595495006707	exoaminopeptidase; Provisional; Region: PRK09961
595495006708	M42 Peptidases, also known as glutamyl aminopeptidase family; Region: M42; cd05638
595495006709	oligomer interface [polypeptide binding]; other site
595495006710	active site
595495006711	metal binding site [ion binding]; metal-binding site
595495006712	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
595495006713	dimerization domain swap beta strand [polypeptide binding]; other site
595495006714	regulatory protein interface [polypeptide binding]; other site
595495006715	active site
595495006716	regulatory phosphorylation site [posttranslational modification]; other site
595495006717	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
595495006718	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
595495006719	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
595495006720	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
595495006721	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
595495006722	active site
595495006723	phosphorylation site [posttranslational modification]
595495006724	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
595495006725	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495006726	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
595495006727	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495006728	active site
595495006729	phosphorylation site [posttranslational modification]
595495006730	intermolecular recognition site; other site
595495006731	dimerization interface [polypeptide binding]; other site
595495006732	LytTr DNA-binding domain; Region: LytTR; pfam04397
595495006733	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
595495006734	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
595495006735	GAF domain; Region: GAF; pfam01590
595495006736	Histidine kinase; Region: His_kinase; pfam06580
595495006737	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495006738	ATP binding site [chemical binding]; other site
595495006739	Mg2+ binding site [ion binding]; other site
595495006740	G-X-G motif; other site
595495006741	aminotransferase; Validated; Region: PRK08175
595495006742	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
595495006743	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495006744	homodimer interface [polypeptide binding]; other site
595495006745	catalytic residue [active]
595495006746	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
595495006747	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
595495006748	putative acyl-acceptor binding pocket; other site
595495006749	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
595495006750	hypothetical protein; Provisional; Region: PRK10316
595495006751	YfdX protein; Region: YfdX; pfam10938
595495006752	formyl-coenzyme A transferase; Provisional; Region: PRK05398
595495006753	CoA-transferase family III; Region: CoA_transf_3; pfam02515
595495006754	putative oxalyl-CoA decarboxylase; Validated; Region: PRK09259
595495006755	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
595495006756	PYR/PP interface [polypeptide binding]; other site
595495006757	dimer interface [polypeptide binding]; other site
595495006758	TPP binding site [chemical binding]; other site
595495006759	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495006760	Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL...; Region: TPP_BZL_OCoD_HPCL; cd02004
595495006761	TPP-binding site; other site
595495006762	dimer interface [polypeptide binding]; other site
595495006763	putative transporter YfdV; Provisional; Region: PRK09903
595495006764	putative CoA-transferase; Provisional; Region: PRK11430
595495006765	CoA-transferase family III; Region: CoA_transf_3; pfam02515
595495006766	hybrid sensory histidine kinase in two-component regulatory system with EvgA; Provisional; Region: PRK09959
595495006767	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
595495006768	substrate binding pocket [chemical binding]; other site
595495006769	membrane-bound complex binding site; other site
595495006770	hinge residues; other site
595495006771	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
595495006772	substrate binding pocket [chemical binding]; other site
595495006773	membrane-bound complex binding site; other site
595495006774	hinge residues; other site
595495006775	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
595495006776	dimer interface [polypeptide binding]; other site
595495006777	phosphorylation site [posttranslational modification]
595495006778	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495006779	ATP binding site [chemical binding]; other site
595495006780	Mg2+ binding site [ion binding]; other site
595495006781	G-X-G motif; other site
595495006782	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495006783	active site
595495006784	phosphorylation site [posttranslational modification]
595495006785	intermolecular recognition site; other site
595495006786	dimerization interface [polypeptide binding]; other site
595495006787	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
595495006788	putative binding surface; other site
595495006789	active site
595495006790	DNA-binding transcriptional activator EvgA; Provisional; Region: PRK09958
595495006791	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495006792	active site
595495006793	phosphorylation site [posttranslational modification]
595495006794	intermolecular recognition site; other site
595495006795	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
595495006796	DNA binding residues [nucleotide binding]
595495006797	dimerization interface [polypeptide binding]; other site
595495006798	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
595495006799	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
595495006800	HlyD family secretion protein; Region: HlyD_3; pfam13437
595495006801	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
595495006802	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495006803	putative substrate translocation pore; other site
595495006804	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495006805	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
595495006806	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
595495006807	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
595495006808	catalytic residue [active]
595495006809	fructuronate transporter; Provisional; Region: PRK10034; cl15264
595495006810	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
595495006811	DNA binding site [nucleotide binding]
595495006812	domain linker motif; other site
595495006813	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
595495006814	Ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_sucrose_transcription_regulator; cd06288
595495006815	putative dimerization interface [polypeptide binding]; other site
595495006816	putative ligand binding site [chemical binding]; other site
595495006817	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
595495006818	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
595495006819	substrate binding [chemical binding]; other site
595495006820	active site
595495006821	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
595495006822	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
595495006823	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
595495006824	putative substrate binding site [chemical binding]; other site
595495006825	putative ATP binding site [chemical binding]; other site
595495006826	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
595495006827	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495006828	putative substrate translocation pore; other site
595495006829	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
595495006830	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
595495006831	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
595495006832	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
595495006833	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
595495006834	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
595495006835	dimer interface [polypeptide binding]; other site
595495006836	active site
595495006837	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
595495006838	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
595495006839	substrate binding site [chemical binding]; other site
595495006840	oxyanion hole (OAH) forming residues; other site
595495006841	trimer interface [polypeptide binding]; other site
595495006842	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
595495006843	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
595495006844	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
595495006845	catalytic core [active]
595495006846	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
595495006847	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
595495006848	PapC N-terminal domain; Region: PapC_N; pfam13954
595495006849	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
595495006850	PapC C-terminal domain; Region: PapC_C; pfam13953
595495006851	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
595495006852	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
595495006853	Fimbrial protein; Region: Fimbrial; cl01416
595495006854	Fimbrial protein; Region: Fimbrial; cl01416
595495006855	Fimbrial protein; Region: Fimbrial; cl01416
595495006856	Protein of unknown function (DUF2544); Region: DUF2544; pfam11245
595495006857	hypothetical protein; Provisional; Region: PRK04946
595495006858	Smr domain; Region: Smr; pfam01713
595495006859	HemK family putative methylases; Region: hemK_fam; TIGR00536
595495006860	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495006861	S-adenosylmethionine binding site [chemical binding]; other site
595495006862	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
595495006863	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
595495006864	Tetramer interface [polypeptide binding]; other site
595495006865	active site
595495006866	FMN-binding site [chemical binding]; other site
595495006867	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
595495006868	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
595495006869	hypothetical protein; Provisional; Region: PRK10621
595495006870	Predicted permeases [General function prediction only]; Region: COG0730
595495006871	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
595495006872	YfcL protein; Region: YfcL; pfam08891
595495006873	Uncharacterized conserved protein [Function unknown]; Region: COG4121
595495006874	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
595495006875	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
595495006876	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
595495006877	dimer interface [polypeptide binding]; other site
595495006878	active site
595495006879	putative transporter; Provisional; Region: PRK12382
595495006880	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495006881	putative substrate translocation pore; other site
595495006882	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
595495006883	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
595495006884	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
595495006885	ligand binding site [chemical binding]; other site
595495006886	NAD binding site [chemical binding]; other site
595495006887	catalytic site [active]
595495006888	homodimer interface [polypeptide binding]; other site
595495006889	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
595495006890	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
595495006891	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
595495006892	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
595495006893	dimerization interface 3.5A [polypeptide binding]; other site
595495006894	active site
595495006895	hypothetical protein; Provisional; Region: PRK10847
595495006896	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
595495006897	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
595495006898	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
595495006899	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
595495006900	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
595495006901	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
595495006902	cell division protein DedD; Provisional; Region: PRK11633
595495006903	Sporulation related domain; Region: SPOR; pfam05036
595495006904	colicin V production protein; Provisional; Region: PRK10845
595495006905	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
595495006906	amidophosphoribosyltransferase; Provisional; Region: PRK09246
595495006907	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
595495006908	active site
595495006909	tetramer interface [polypeptide binding]; other site
595495006910	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
595495006911	active site
595495006912	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
595495006913	Flavoprotein; Region: Flavoprotein; pfam02441
595495006914	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
595495006915	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
595495006916	substrate binding pocket [chemical binding]; other site
595495006917	membrane-bound complex binding site; other site
595495006918	hinge residues; other site
595495006919	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
595495006920	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
595495006921	substrate binding pocket [chemical binding]; other site
595495006922	membrane-bound complex binding site; other site
595495006923	hinge residues; other site
595495006924	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
595495006925	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495006926	dimer interface [polypeptide binding]; other site
595495006927	conserved gate region; other site
595495006928	putative PBP binding loops; other site
595495006929	ABC-ATPase subunit interface; other site
595495006930	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495006931	dimer interface [polypeptide binding]; other site
595495006932	conserved gate region; other site
595495006933	putative PBP binding loops; other site
595495006934	ABC-ATPase subunit interface; other site
595495006935	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
595495006936	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
595495006937	Walker A/P-loop; other site
595495006938	ATP binding site [chemical binding]; other site
595495006939	Q-loop/lid; other site
595495006940	ABC transporter signature motif; other site
595495006941	Walker B; other site
595495006942	D-loop; other site
595495006943	H-loop/switch region; other site
595495006944	putative transposase; Provisional; Region: PRK09857
595495006945	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
595495006946	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
595495006947	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
595495006948	putative NAD(P) binding site [chemical binding]; other site
595495006949	putative active site [active]
595495006950	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
595495006951	homooctamer interface [polypeptide binding]; other site
595495006952	active site
595495006953	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
595495006954	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
595495006955	C-terminal domain interface [polypeptide binding]; other site
595495006956	GSH binding site (G-site) [chemical binding]; other site
595495006957	dimer interface [polypeptide binding]; other site
595495006958	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
595495006959	N-terminal domain interface [polypeptide binding]; other site
595495006960	putative dimer interface [polypeptide binding]; other site
595495006961	active site
595495006962	glutathione S-transferase; Provisional; Region: PRK15113
595495006963	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
595495006964	C-terminal domain interface [polypeptide binding]; other site
595495006965	GSH binding site (G-site) [chemical binding]; other site
595495006966	dimer interface [polypeptide binding]; other site
595495006967	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
595495006968	N-terminal domain interface [polypeptide binding]; other site
595495006969	putative dimer interface [polypeptide binding]; other site
595495006970	putative substrate binding pocket (H-site) [chemical binding]; other site
595495006971	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
595495006972	active site
595495006973	metal binding site [ion binding]; metal-binding site
595495006974	homotetramer interface [polypeptide binding]; other site
595495006975	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
595495006976	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
595495006977	nudix motif; other site
595495006978	hypothetical protein; Provisional; Region: PRK11588
595495006979	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
595495006980	phosphate acetyltransferase; Reviewed; Region: PRK05632
595495006981	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
595495006982	DRTGG domain; Region: DRTGG; pfam07085
595495006983	phosphate acetyltransferase; Region: pta; TIGR00651
595495006984	propionate/acetate kinase; Provisional; Region: PRK12379
595495006985	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
595495006986	hypothetical protein; Provisional; Region: PRK01816
595495006987	hypothetical protein; Validated; Region: PRK05445
595495006988	putative phosphatase; Provisional; Region: PRK11587
595495006989	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495006990	motif II; other site
595495006991	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
595495006992	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
595495006993	TrkA-C domain; Region: TrkA_C; pfam02080
595495006994	TrkA-C domain; Region: TrkA_C; pfam02080
595495006995	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
595495006996	5'-nucleotidase; Provisional; Region: PRK03826
595495006997	aminotransferase AlaT; Validated; Region: PRK09265
595495006998	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
595495006999	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495007000	homodimer interface [polypeptide binding]; other site
595495007001	catalytic residue [active]
595495007002	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
595495007003	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495007004	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
595495007005	putative dimerization interface [polypeptide binding]; other site
595495007006	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
595495007007	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
595495007008	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
595495007009	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
595495007010	NADH dehydrogenase subunit D; Validated; Region: PRK06075
595495007011	NADH dehydrogenase subunit E; Validated; Region: PRK07539
595495007012	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
595495007013	putative dimer interface [polypeptide binding]; other site
595495007014	[2Fe-2S] cluster binding site [ion binding]; other site
595495007015	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
595495007016	SLBB domain; Region: SLBB; pfam10531
595495007017	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
595495007018	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
595495007019	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
595495007020	catalytic loop [active]
595495007021	iron binding site [ion binding]; other site
595495007022	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
595495007023	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
595495007024	[4Fe-4S] binding site [ion binding]; other site
595495007025	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
595495007026	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
595495007027	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
595495007028	4Fe-4S binding domain; Region: Fer4; pfam00037
595495007029	4Fe-4S binding domain; Region: Fer4; pfam00037
595495007030	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
595495007031	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
595495007032	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
595495007033	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
595495007034	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
595495007035	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
595495007036	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
595495007037	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
595495007038	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
595495007039	Domain of unknown function (DUF1877); Region: DUF1877; pfam08974
595495007040	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
595495007041	deubiquitinase; Provisional; Region: PRK11836
595495007042	ribonuclease BN; Region: true_RNase_BN; TIGR02649
595495007043	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
595495007044	Coenzyme A binding pocket [chemical binding]; other site
595495007045	hypothetical protein; Provisional; Region: PRK10404
595495007046	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
595495007047	isochorismate synthases; Region: isochor_syn; TIGR00543
595495007048	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
595495007049	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
595495007050	dimer interface [polypeptide binding]; other site
595495007051	tetramer interface [polypeptide binding]; other site
595495007052	PYR/PP interface [polypeptide binding]; other site
595495007053	TPP binding site [chemical binding]; other site
595495007054	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
595495007055	TPP-binding site; other site
595495007056	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
595495007057	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
595495007058	nucleophilic elbow; other site
595495007059	catalytic triad; other site
595495007060	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
595495007061	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
595495007062	substrate binding site [chemical binding]; other site
595495007063	oxyanion hole (OAH) forming residues; other site
595495007064	trimer interface [polypeptide binding]; other site
595495007065	O-succinylbenzoate synthase; Provisional; Region: PRK05105
595495007066	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
595495007067	active site
595495007068	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
595495007069	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
595495007070	acyl-activating enzyme (AAE) consensus motif; other site
595495007071	putative AMP binding site [chemical binding]; other site
595495007072	putative active site [active]
595495007073	putative CoA binding site [chemical binding]; other site
595495007074	signal transduction protein PmrD; Provisional; Region: PRK15450
595495007075	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
595495007076	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
595495007077	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
595495007078	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
595495007079	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
595495007080	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
595495007081	putative active site [active]
595495007082	putative catalytic site [active]
595495007083	putative Zn binding site [ion binding]; other site
595495007084	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
595495007085	ArnA, N-terminal formyltransferase domain; Region: FMT_core_ArnA_N; cd08644
595495007086	substrate binding site [chemical binding]; other site
595495007087	cosubstrate binding site; other site
595495007088	catalytic site [active]
595495007089	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
595495007090	active site
595495007091	hexamer interface [polypeptide binding]; other site
595495007092	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
595495007093	NAD binding site [chemical binding]; other site
595495007094	substrate binding site [chemical binding]; other site
595495007095	active site
595495007096	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
595495007097	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
595495007098	Ligand binding site; other site
595495007099	Putative Catalytic site; other site
595495007100	DXD motif; other site
595495007101	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
595495007102	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
595495007103	inhibitor-cofactor binding pocket; inhibition site
595495007104	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495007105	catalytic residue [active]
595495007106	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
595495007107	catalytic core [active]
595495007108	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
595495007109	YfaZ precursor; Region: YfaZ; pfam07437
595495007110	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
595495007111	hypothetical protein; Provisional; Region: PRK03673
595495007112	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
595495007113	putative MPT binding site; other site
595495007114	Competence-damaged protein; Region: CinA; cl00666
595495007115	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
595495007116	hypothetical protein; Provisional; Region: PRK09956
595495007117	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
595495007118	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
595495007119	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
595495007120	Cysteine-rich domain; Region: CCG; pfam02754
595495007121	Cysteine-rich domain; Region: CCG; pfam02754
595495007122	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
595495007123	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
595495007124	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
595495007125	hydroxyglutarate oxidase; Provisional; Region: PRK11728
595495007126	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
595495007127	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
595495007128	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495007129	putative substrate translocation pore; other site
595495007130	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
595495007131	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
595495007132	active site
595495007133	catalytic site [active]
595495007134	metal binding site [ion binding]; metal-binding site
595495007135	hypothetical protein; Provisional; Region: PRK09902
595495007136	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
595495007137	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
595495007138	catalytic loop [active]
595495007139	iron binding site [ion binding]; other site
595495007140	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
595495007141	dimer interface [polypeptide binding]; other site
595495007142	putative radical transfer pathway; other site
595495007143	diiron center [ion binding]; other site
595495007144	tyrosyl radical; other site
595495007145	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
595495007146	ATP cone domain; Region: ATP-cone; pfam03477
595495007147	Class I ribonucleotide reductase; Region: RNR_I; cd01679
595495007148	active site
595495007149	dimer interface [polypeptide binding]; other site
595495007150	catalytic residues [active]
595495007151	effector binding site; other site
595495007152	R2 peptide binding site; other site
595495007153	adhesin; Provisional; Region: PRK09752
595495007154	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
595495007155	Autotransporter beta-domain; Region: Autotransporter; pfam03797
595495007156	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
595495007157	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495007158	S-adenosylmethionine binding site [chemical binding]; other site
595495007159	DNA gyrase subunit A; Validated; Region: PRK05560
595495007160	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
595495007161	CAP-like domain; other site
595495007162	active site
595495007163	primary dimer interface [polypeptide binding]; other site
595495007164	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
595495007165	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
595495007166	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
595495007167	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
595495007168	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
595495007169	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
595495007170	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4685
595495007171	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3234
595495007172	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
595495007173	MG2 domain; Region: A2M_N; pfam01835
595495007174	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cl17457
595495007175	Alpha-2-macroglobulin family; Region: A2M; pfam00207
595495007176	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267
595495007177	Predicted secreted protein [Function unknown]; Region: COG5445
595495007178	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
595495007179	Predicted secreted protein [Function unknown]; Region: COG5445
595495007180	Stage II sporulation protein; Region: SpoIID; pfam08486
595495007181	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
595495007182	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4676
595495007183	Uncharacterized protein conserved in bacteria (DUF2135); Region: DUF2135; pfam09906
595495007184	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
595495007185	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
595495007186	dimer interface [polypeptide binding]; other site
595495007187	phosphorylation site [posttranslational modification]
595495007188	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495007189	ATP binding site [chemical binding]; other site
595495007190	Mg2+ binding site [ion binding]; other site
595495007191	G-X-G motif; other site
595495007192	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
595495007193	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495007194	active site
595495007195	phosphorylation site [posttranslational modification]
595495007196	intermolecular recognition site; other site
595495007197	dimerization interface [polypeptide binding]; other site
595495007198	transcriptional regulator RcsB; Provisional; Region: PRK10840
595495007199	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495007200	active site
595495007201	phosphorylation site [posttranslational modification]
595495007202	intermolecular recognition site; other site
595495007203	dimerization interface [polypeptide binding]; other site
595495007204	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
595495007205	DNA binding residues [nucleotide binding]
595495007206	dimerization interface [polypeptide binding]; other site
595495007207	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
595495007208	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495007209	ATP binding site [chemical binding]; other site
595495007210	G-X-G motif; other site
595495007211	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
595495007212	putative binding surface; other site
595495007213	active site
595495007214	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
595495007215	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
595495007216	trimer interface [polypeptide binding]; other site
595495007217	eyelet of channel; other site
595495007218	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
595495007219	ApbE family; Region: ApbE; pfam02424
595495007220	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
595495007221	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
595495007222	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495007223	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495007224	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
595495007225	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
595495007226	DNA binding site [nucleotide binding]
595495007227	active site
595495007228	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
595495007229	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
595495007230	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
595495007231	Walker A/P-loop; other site
595495007232	ATP binding site [chemical binding]; other site
595495007233	Q-loop/lid; other site
595495007234	ABC transporter signature motif; other site
595495007235	Walker B; other site
595495007236	D-loop; other site
595495007237	H-loop/switch region; other site
595495007238	malate:quinone oxidoreductase; Validated; Region: PRK05257
595495007239	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
595495007240	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
595495007241	secondary substrate binding site; other site
595495007242	primary substrate binding site; other site
595495007243	inhibition loop; other site
595495007244	dimerization interface [polypeptide binding]; other site
595495007245	tRNA synthetases class I (R); Region: tRNA-synt_1d; pfam00750
595495007246	ferredoxin-type protein; Provisional; Region: PRK10194
595495007247	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
595495007248	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
595495007249	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
595495007250	[4Fe-4S] binding site [ion binding]; other site
595495007251	molybdopterin cofactor binding site; other site
595495007252	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
595495007253	molybdopterin cofactor binding site; other site
595495007254	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
595495007255	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
595495007256	4Fe-4S binding domain; Region: Fer4_5; pfam12801
595495007257	4Fe-4S binding domain; Region: Fer4_6; pfam12837
595495007258	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
595495007259	cytochrome c-type protein NapC; Provisional; Region: PRK10617
595495007260	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
595495007261	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
595495007262	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
595495007263	Walker A/P-loop; other site
595495007264	ATP binding site [chemical binding]; other site
595495007265	Q-loop/lid; other site
595495007266	ABC transporter signature motif; other site
595495007267	Walker B; other site
595495007268	D-loop; other site
595495007269	H-loop/switch region; other site
595495007270	heme exporter protein CcmB; Region: ccmB; TIGR01190
595495007271	heme exporter protein CcmC; Region: ccmC; TIGR01191
595495007272	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
595495007273	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13165
595495007274	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
595495007275	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
595495007276	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
595495007277	catalytic residues [active]
595495007278	central insert; other site
595495007279	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
595495007280	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
595495007281	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
595495007282	binding surface
595495007283	TPR motif; other site
595495007284	transcriptional regulator NarP; Provisional; Region: PRK10403
595495007285	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495007286	active site
595495007287	phosphorylation site [posttranslational modification]
595495007288	intermolecular recognition site; other site
595495007289	dimerization interface [polypeptide binding]; other site
595495007290	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
595495007291	DNA binding residues [nucleotide binding]
595495007292	dimerization interface [polypeptide binding]; other site
595495007293	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
595495007294	hypothetical protein; Provisional; Region: PRK09945
595495007295	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
595495007296	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
595495007297	Autotransporter beta-domain; Region: Autotransporter; pfam03797
595495007298	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
595495007299	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
595495007300	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
595495007301	Sulfatase; Region: Sulfatase; pfam00884
595495007302	hypothetical protein; Provisional; Region: PRK13689
595495007303	Nucleoid-associated protein [General function prediction only]; Region: COG3081
595495007304	nucleoid-associated protein NdpA; Validated; Region: PRK00378
595495007305	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
595495007306	5S rRNA interface [nucleotide binding]; other site
595495007307	CTC domain interface [polypeptide binding]; other site
595495007308	L16 interface [polypeptide binding]; other site
595495007309	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
595495007310	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
595495007311	ATP binding site [chemical binding]; other site
595495007312	putative Mg++ binding site [ion binding]; other site
595495007313	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
595495007314	nucleotide binding region [chemical binding]; other site
595495007315	ATP-binding site [chemical binding]; other site
595495007316	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
595495007317	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
595495007318	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
595495007319	RNA binding surface [nucleotide binding]; other site
595495007320	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
595495007321	active site
595495007322	uracil binding [chemical binding]; other site
595495007323	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495007324	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
595495007325	putative substrate translocation pore; other site
595495007326	hypothetical protein; Provisional; Region: PRK11835
595495007327	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
595495007328	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
595495007329	Walker A/P-loop; other site
595495007330	ATP binding site [chemical binding]; other site
595495007331	Q-loop/lid; other site
595495007332	ABC transporter signature motif; other site
595495007333	Walker B; other site
595495007334	D-loop; other site
595495007335	H-loop/switch region; other site
595495007336	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
595495007337	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
595495007338	Walker A/P-loop; other site
595495007339	ATP binding site [chemical binding]; other site
595495007340	Q-loop/lid; other site
595495007341	ABC transporter signature motif; other site
595495007342	Walker B; other site
595495007343	D-loop; other site
595495007344	H-loop/switch region; other site
595495007345	microcin C ABC transporter permease; Provisional; Region: PRK15021
595495007346	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495007347	dimer interface [polypeptide binding]; other site
595495007348	conserved gate region; other site
595495007349	ABC-ATPase subunit interface; other site
595495007350	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
595495007351	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495007352	dimer interface [polypeptide binding]; other site
595495007353	conserved gate region; other site
595495007354	putative PBP binding loops; other site
595495007355	ABC-ATPase subunit interface; other site
595495007356	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
595495007357	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
595495007358	phage resistance protein; Provisional; Region: PRK10551
595495007359	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
595495007360	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
595495007361	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
595495007362	NlpC/P60 family; Region: NLPC_P60; pfam00877
595495007363	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
595495007364	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
595495007365	active site
595495007366	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
595495007367	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
595495007368	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
595495007369	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
595495007370	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
595495007371	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
595495007372	elongation factor P; Provisional; Region: PRK04542
595495007373	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
595495007374	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
595495007375	RNA binding site [nucleotide binding]; other site
595495007376	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
595495007377	RNA binding site [nucleotide binding]; other site
595495007378	Flagellin N-methylase; Region: FliB; pfam03692
595495007379	sugar efflux transporter B; Provisional; Region: PRK15011
595495007380	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495007381	putative substrate translocation pore; other site
595495007382	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
595495007383	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
595495007384	active site
595495007385	phosphorylation site [posttranslational modification]
595495007386	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
595495007387	dimerization domain swap beta strand [polypeptide binding]; other site
595495007388	regulatory protein interface [polypeptide binding]; other site
595495007389	active site
595495007390	regulatory phosphorylation site [posttranslational modification]; other site
595495007391	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
595495007392	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
595495007393	putative substrate binding site [chemical binding]; other site
595495007394	putative ATP binding site [chemical binding]; other site
595495007395	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
595495007396	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
595495007397	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
595495007398	active site
595495007399	P-loop; other site
595495007400	phosphorylation site [posttranslational modification]
595495007401	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
595495007402	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
595495007403	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
595495007404	substrate binding site [chemical binding]; other site
595495007405	ATP binding site [chemical binding]; other site
595495007406	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
595495007407	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
595495007408	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
595495007409	Nucleoside recognition; Region: Gate; pfam07670
595495007410	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
595495007411	DNA-binding transcriptional activator YeiL; Provisional; Region: PRK10402
595495007412	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
595495007413	ligand binding site [chemical binding]; other site
595495007414	flexible hinge region; other site
595495007415	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
595495007416	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
595495007417	active site
595495007418	tetramer interface [polypeptide binding]; other site
595495007419	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
595495007420	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
595495007421	Nucleoside recognition; Region: Gate; pfam07670
595495007422	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
595495007423	putative kinase; Provisional; Region: PRK09954
595495007424	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
595495007425	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
595495007426	substrate binding site [chemical binding]; other site
595495007427	ATP binding site [chemical binding]; other site
595495007428	endonuclease IV; Provisional; Region: PRK01060
595495007429	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
595495007430	AP (apurinic/apyrimidinic) site pocket; other site
595495007431	DNA interaction; other site
595495007432	Metal-binding active site; metal-binding site
595495007433	conserved hypothetical integral membrane protein; Region: TIGR00698
595495007434	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
595495007435	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495007436	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
595495007437	putative dimerization interface [polypeptide binding]; other site
595495007438	lysine transporter; Provisional; Region: PRK10836
595495007439	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
595495007440	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
595495007441	N-terminal plug; other site
595495007442	ligand-binding site [chemical binding]; other site
595495007443	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
595495007444	S-formylglutathione hydrolase; Region: PLN02442
595495007445	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
595495007446	homodecamer interface [polypeptide binding]; other site
595495007447	GTP cyclohydrolase I; Provisional; Region: PLN03044
595495007448	active site
595495007449	putative catalytic site residues [active]
595495007450	zinc binding site [ion binding]; other site
595495007451	GTP-CH-I/GFRP interaction surface; other site
595495007452	Predicted membrane protein [Function unknown]; Region: COG2311
595495007453	hypothetical protein; Provisional; Region: PRK10835
595495007454	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
595495007455	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
595495007456	DNA binding site [nucleotide binding]
595495007457	domain linker motif; other site
595495007458	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
595495007459	dimerization interface (closed form) [polypeptide binding]; other site
595495007460	ligand binding site [chemical binding]; other site
595495007461	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
595495007462	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
595495007463	ligand binding site [chemical binding]; other site
595495007464	calcium binding site [ion binding]; other site
595495007465	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
595495007466	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
595495007467	Walker A/P-loop; other site
595495007468	ATP binding site [chemical binding]; other site
595495007469	Q-loop/lid; other site
595495007470	ABC transporter signature motif; other site
595495007471	Walker B; other site
595495007472	D-loop; other site
595495007473	H-loop/switch region; other site
595495007474	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
595495007475	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
595495007476	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
595495007477	TM-ABC transporter signature motif; other site
595495007478	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
595495007479	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
595495007480	homodimer interface [polypeptide binding]; other site
595495007481	active site
595495007482	FMN binding site [chemical binding]; other site
595495007483	substrate binding site [chemical binding]; other site
595495007484	4Fe-4S binding domain; Region: Fer4; pfam00037
595495007485	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
595495007486	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
595495007487	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
595495007488	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
595495007489	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
595495007490	putative active site [active]
595495007491	cytidine deaminase; Provisional; Region: PRK09027
595495007492	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
595495007493	active site
595495007494	catalytic motif [active]
595495007495	Zn binding site [ion binding]; other site
595495007496	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
595495007497	active site
595495007498	catalytic motif [active]
595495007499	Zn binding site [ion binding]; other site
595495007500	hypothetical protein; Provisional; Region: PRK10711
595495007501	hypothetical protein; Provisional; Region: PRK01821
595495007502	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
595495007503	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
595495007504	FMN binding site [chemical binding]; other site
595495007505	active site
595495007506	catalytic residues [active]
595495007507	substrate binding site [chemical binding]; other site
595495007508	Outer membrane efflux protein; Region: OEP; pfam02321
595495007509	Outer membrane efflux protein; Region: OEP; pfam02321
595495007510	oxidoreductase; Provisional; Region: PRK12743
595495007511	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
595495007512	NAD(P) binding site [chemical binding]; other site
595495007513	active site
595495007514	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
595495007515	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
595495007516	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
595495007517	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
595495007518	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
595495007519	D-lactate dehydrogenase; Provisional; Region: PRK11183
595495007520	FAD binding domain; Region: FAD_binding_4; pfam01565
595495007521	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
595495007522	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
595495007523	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
595495007524	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
595495007525	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
595495007526	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495007527	dimer interface [polypeptide binding]; other site
595495007528	conserved gate region; other site
595495007529	ABC-ATPase subunit interface; other site
595495007530	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
595495007531	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
595495007532	Walker A/P-loop; other site
595495007533	ATP binding site [chemical binding]; other site
595495007534	Q-loop/lid; other site
595495007535	ABC transporter signature motif; other site
595495007536	Walker B; other site
595495007537	D-loop; other site
595495007538	H-loop/switch region; other site
595495007539	CBS domain; Region: CBS; pfam00571
595495007540	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
595495007541	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495007542	dimer interface [polypeptide binding]; other site
595495007543	conserved gate region; other site
595495007544	putative PBP binding loops; other site
595495007545	ABC-ATPase subunit interface; other site
595495007546	hypothetical protein; Provisional; Region: PRK13681
595495007547	transcriptional regulator MirA; Provisional; Region: PRK15043
595495007548	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
595495007549	DNA binding residues [nucleotide binding]
595495007550	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
595495007551	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
595495007552	GAF domain; Region: GAF; pfam01590
595495007553	Histidine kinase; Region: His_kinase; pfam06580
595495007554	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495007555	ATP binding site [chemical binding]; other site
595495007556	Mg2+ binding site [ion binding]; other site
595495007557	G-X-G motif; other site
595495007558	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
595495007559	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495007560	active site
595495007561	phosphorylation site [posttranslational modification]
595495007562	intermolecular recognition site; other site
595495007563	dimerization interface [polypeptide binding]; other site
595495007564	LytTr DNA-binding domain; Region: LytTR; pfam04397
595495007565	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
595495007566	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
595495007567	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
595495007568	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
595495007569	VWA domain containing CoxE-like protein; Region: VWA_CoxE; pfam05762
595495007570	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
595495007571	metal ion-dependent adhesion site (MIDAS); other site
595495007572	MoxR-like ATPases [General function prediction only]; Region: COG0714
595495007573	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495007574	Walker A motif; other site
595495007575	ATP binding site [chemical binding]; other site
595495007576	Walker B motif; other site
595495007577	arginine finger; other site
595495007578	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
595495007579	WGR domain of molybdate metabolism regulator and related proteins; Region: WGR_MMR_like; cd07996
595495007580	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
595495007581	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
595495007582	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
595495007583	active site
595495007584	HIGH motif; other site
595495007585	KMSKS motif; other site
595495007586	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
595495007587	tRNA binding surface [nucleotide binding]; other site
595495007588	anticodon binding site; other site
595495007589	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
595495007590	dimer interface [polypeptide binding]; other site
595495007591	putative tRNA-binding site [nucleotide binding]; other site
595495007592	antiporter inner membrane protein; Provisional; Region: PRK11670
595495007593	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
595495007594	Walker A motif; other site
595495007595	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
595495007596	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
595495007597	putative fimbrial assembly chaperone protein StcB; Provisional; Region: PRK15253
595495007598	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
595495007599	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
595495007600	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
595495007601	PapC N-terminal domain; Region: PapC_N; pfam13954
595495007602	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
595495007603	PapC C-terminal domain; Region: PapC_C; pfam13953
595495007604	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
595495007605	putative fimbrial biosynthesis regulatory protein; Provisional; Region: PRK15216
595495007606	Predicted integral membrane protein [Function unknown]; Region: COG5455
595495007607	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
595495007608	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
595495007609	putative metal binding site [ion binding]; other site
595495007610	putative homodimer interface [polypeptide binding]; other site
595495007611	putative homotetramer interface [polypeptide binding]; other site
595495007612	putative homodimer-homodimer interface [polypeptide binding]; other site
595495007613	putative allosteric switch controlling residues; other site
595495007614	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
595495007615	substrate binding site [chemical binding]; other site
595495007616	multimerization interface [polypeptide binding]; other site
595495007617	ATP binding site [chemical binding]; other site
595495007618	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
595495007619	dimer interface [polypeptide binding]; other site
595495007620	substrate binding site [chemical binding]; other site
595495007621	ATP binding site [chemical binding]; other site
595495007622	Lyzozyme M1 (1,4-beta-N-acetylmuramidase) [Cell envelope biogenesis, outer membrane]; Region: Acm; COG3757
595495007623	YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins; Region: GH25_YegX-like; cd06524
595495007624	active site
595495007625	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
595495007626	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
595495007627	DNA-binding site [nucleotide binding]; DNA binding site
595495007628	UTRA domain; Region: UTRA; pfam07702
595495007629	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
595495007630	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
595495007631	substrate binding site [chemical binding]; other site
595495007632	ATP binding site [chemical binding]; other site
595495007633	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
595495007634	nucleoside transporter; Region: 2A0110; TIGR00889
595495007635	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495007636	putative substrate translocation pore; other site
595495007637	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
595495007638	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
595495007639	putative active site; other site
595495007640	catalytic residue [active]
595495007641	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
595495007642	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
595495007643	intersubunit interface [polypeptide binding]; other site
595495007644	active site
595495007645	zinc binding site [ion binding]; other site
595495007646	Na+ binding site [ion binding]; other site
595495007647	D-tagatose-1,6-bisphosphate aldolase subunit GatZ; Provisional; Region: PRK15052
595495007648	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
595495007649	active site
595495007650	phosphorylation site [posttranslational modification]
595495007651	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
595495007652	active site
595495007653	P-loop; other site
595495007654	phosphorylation site [posttranslational modification]
595495007655	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
595495007656	PTS system, galactitol-specific IIC component; Region: EIIC-GAT; TIGR00827
595495007657	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
595495007658	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
595495007659	putative NAD(P) binding site [chemical binding]; other site
595495007660	catalytic Zn binding site [ion binding]; other site
595495007661	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
595495007662	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
595495007663	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
595495007664	lipid kinase; Reviewed; Region: PRK13054
595495007665	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
595495007666	integrase; Provisional; Region: int; PHA02601
595495007667	Phage HP1 integrase, C-terminal catalytic domain. Bacteriophage HP1 and related integrases are found in eubacteria, plasmids and temperate bacteriophages of the P2 family.  They belong to the DNA breaking-rejoining enzyme superfamily, which includes...; Region: HP1_INT_C; cd00797
595495007668	dimer interface [polypeptide binding]; other site
595495007669	active site
595495007670	catalytic residues [active]
595495007671	Int/Topo IB signature motif; other site
595495007672	Regulatory phage protein cox; Region: Phage_Cox; pfam10743
595495007673	DksA-like zinc finger domain containing protein; Region: PHA00080
595495007674	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
595495007675	AAA domain; Region: AAA_21; pfam13304
595495007676	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495007677	Walker B; other site
595495007678	D-loop; other site
595495007679	H-loop/switch region; other site
595495007680	portal vertex protein; Provisional; Region: Q; PHA02536
595495007681	Phage portal protein; Region: Phage_portal; pfam04860
595495007682	terminase ATPase subunit; Provisional; Region: P; PHA02535
595495007683	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
595495007684	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
595495007685	Phage major capsid protein, P2 family; Region: Phage_cap_P2; pfam05125
595495007686	terminase endonuclease subunit; Provisional; Region: M; PHA02537
595495007687	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
595495007688	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
595495007689	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
595495007690	Phage holin family 2; Region: Phage_holin_2; pfam04550
595495007691	The lysozyme from bacteriophage lambda hydrolyses the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc), as do other lysozymes.  But unlike other lysozymes, bacteriophage lambda does not produce a reducing...; Region: bacteriophage_lambda_lysozyme; cd00736
595495007692	N-acetyl-D-glucosamine binding site [chemical binding]; other site
595495007693	catalytic residue [active]
595495007694	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
595495007695	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
595495007696	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
595495007697	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
595495007698	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
595495007699	baseplate wedge subunit; Provisional; Region: W; PHA02516
595495007700	baseplate assembly protein; Provisional; Region: J; PHA02568
595495007701	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
595495007702	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
595495007703	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
595495007704	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
595495007705	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
595495007706	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
595495007707	catalytic residues [active]
595495007708	catalytic nucleophile [active]
595495007709	Presynaptic Site I dimer interface [polypeptide binding]; other site
595495007710	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
595495007711	Synaptic Flat tetramer interface [polypeptide binding]; other site
595495007712	Synaptic Site I dimer interface [polypeptide binding]; other site
595495007713	DNA binding site [nucleotide binding]
595495007714	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
595495007715	DNA-binding interface [nucleotide binding]; DNA binding site
595495007716	major tail sheath protein; Provisional; Region: FI; PHA02560
595495007717	major tail tube protein; Provisional; Region: FII; PHA02600
595495007718	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
595495007719	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
595495007720	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
595495007721	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
595495007722	tail protein; Provisional; Region: D; PHA02561
595495007723	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
595495007724	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
595495007725	putative protease; Provisional; Region: PRK15452
595495007726	Peptidase family U32; Region: Peptidase_U32; pfam01136
595495007727	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
595495007728	putative addiction module antidote protein, CC2985 family; Region: antidote_CC2985; TIGR02606
595495007729	Uncharacterized conserved protein [Function unknown]; Region: COG3422
595495007730	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
595495007731	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
595495007732	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495007733	active site
595495007734	phosphorylation site [posttranslational modification]
595495007735	intermolecular recognition site; other site
595495007736	dimerization interface [polypeptide binding]; other site
595495007737	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
595495007738	DNA binding site [nucleotide binding]
595495007739	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
595495007740	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
595495007741	dimerization interface [polypeptide binding]; other site
595495007742	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
595495007743	dimer interface [polypeptide binding]; other site
595495007744	phosphorylation site [posttranslational modification]
595495007745	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495007746	ATP binding site [chemical binding]; other site
595495007747	Mg2+ binding site [ion binding]; other site
595495007748	G-X-G motif; other site
595495007749	putative transporter; Provisional; Region: PRK10504
595495007750	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495007751	putative substrate translocation pore; other site
595495007752	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495007753	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
595495007754	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
595495007755	Protein export membrane protein; Region: SecD_SecF; cl14618
595495007756	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
595495007757	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
595495007758	HlyD family secretion protein; Region: HlyD_3; pfam13437
595495007759	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
595495007760	metal ion-dependent adhesion site (MIDAS); other site
595495007761	Protein phosphatase 2C; Region: PP2C_2; pfam13672
595495007762	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3779
595495007763	Uncharacterized protein conserved in bacteria (DUF2314); Region: DUF2314; pfam10077
595495007764	Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only]; Region: COG4248
595495007765	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
595495007766	substrate binding site [chemical binding]; other site
595495007767	activation loop (A-loop); other site
595495007768	Y-family of DNA polymerases; Region: PolY; cl12025
595495007769	putative chaperone; Provisional; Region: PRK11678
595495007770	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
595495007771	nucleotide binding site [chemical binding]; other site
595495007772	putative NEF/HSP70 interaction site [polypeptide binding]; other site
595495007773	SBD interface [polypeptide binding]; other site
595495007774	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
595495007775	AlkA N-terminal domain; Region: AlkA_N; smart01009
595495007776	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
595495007777	minor groove reading motif; other site
595495007778	helix-hairpin-helix signature motif; other site
595495007779	substrate binding pocket [chemical binding]; other site
595495007780	active site
595495007781	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
595495007782	putative diguanylate cyclase; Provisional; Region: PRK09776
595495007783	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
595495007784	putative active site [active]
595495007785	heme pocket [chemical binding]; other site
595495007786	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
595495007787	putative active site [active]
595495007788	heme pocket [chemical binding]; other site
595495007789	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
595495007790	putative active site [active]
595495007791	heme pocket [chemical binding]; other site
595495007792	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
595495007793	metal binding site [ion binding]; metal-binding site
595495007794	active site
595495007795	I-site; other site
595495007796	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
595495007797	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
595495007798	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
595495007799	ATP-binding site [chemical binding]; other site
595495007800	Sugar specificity; other site
595495007801	Pyrimidine base specificity; other site
595495007802	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
595495007803	trimer interface [polypeptide binding]; other site
595495007804	active site
595495007805	putative assembly protein; Provisional; Region: PRK10833
595495007806	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
595495007807	Uncharacterized conserved small protein [Function unknown]; Region: COG5606
595495007808	Phage-related protein [Function unknown]; Region: COG4679
595495007809	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
595495007810	FOG: CBS domain [General function prediction only]; Region: COG0517
595495007811	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
595495007812	Transporter associated domain; Region: CorC_HlyC; smart01091
595495007813	polysaccharide export protein Wza; Provisional; Region: PRK15078
595495007814	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
595495007815	SLBB domain; Region: SLBB; pfam10531
595495007816	Low molecular weight phosphatase family; Region: LMWPc; cd00115
595495007817	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
595495007818	active site
595495007819	tyrosine kinase; Provisional; Region: PRK11519
595495007820	Chain length determinant protein; Region: Wzz; pfam02706
595495007821	Chain length determinant protein; Region: Wzz; cl15801
595495007822	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
595495007823	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
595495007824	putative glycosyl transferase; Provisional; Region: PRK10018
595495007825	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
595495007826	active site
595495007827	putative acyl transferase; Provisional; Region: PRK10191
595495007828	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
595495007829	trimer interface [polypeptide binding]; other site
595495007830	active site
595495007831	substrate binding site [chemical binding]; other site
595495007832	CoA binding site [chemical binding]; other site
595495007833	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
595495007834	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
595495007835	putative colanic acid polymerase WcaD; Region: WcaD; TIGR04010
595495007836	putative glycosyl transferase; Provisional; Region: PRK10063
595495007837	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
595495007838	metal-binding site
595495007839	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
595495007840	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
595495007841	putative trimer interface [polypeptide binding]; other site
595495007842	putative active site [active]
595495007843	putative substrate binding site [chemical binding]; other site
595495007844	putative CoA binding site [chemical binding]; other site
595495007845	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
595495007846	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
595495007847	NADP-binding site; other site
595495007848	homotetramer interface [polypeptide binding]; other site
595495007849	substrate binding site [chemical binding]; other site
595495007850	homodimer interface [polypeptide binding]; other site
595495007851	active site
595495007852	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
595495007853	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
595495007854	NADP binding site [chemical binding]; other site
595495007855	active site
595495007856	putative substrate binding site [chemical binding]; other site
595495007857	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
595495007858	active site
595495007859	GDP-Mannose binding site [chemical binding]; other site
595495007860	dimer interface [polypeptide binding]; other site
595495007861	modified nudix motif
595495007862	metal binding site [ion binding]; metal-binding site
595495007863	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
595495007864	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
595495007865	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
595495007866	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
595495007867	Substrate binding site; other site
595495007868	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
595495007869	phosphomannomutase CpsG; Provisional; Region: PRK15414
595495007870	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
595495007871	active site
595495007872	substrate binding site [chemical binding]; other site
595495007873	metal binding site [ion binding]; metal-binding site
595495007874	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
595495007875	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
595495007876	colanic acid exporter; Provisional; Region: PRK10459
595495007877	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
595495007878	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
595495007879	colanic acid biosynthesis pyruvyl transferase WcaK; Region: wcaK; TIGR04006
595495007880	colanic acid biosynthesis glycosyltransferase WcaL; Region: wcaL; TIGR04005
595495007881	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
595495007882	putative ADP-binding pocket [chemical binding]; other site
595495007883	putative colanic acid biosynthesis protein; Provisional; Region: wcaM; PRK10123
595495007884	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
595495007885	active site
595495007886	tetramer interface; other site
595495007887	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
595495007888	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
595495007889	O-antigen polysaccharide polymerase Wzy; Region: O-ag_pol_Wzy; pfam14296
595495007890	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
595495007891	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
595495007892	active site
595495007893	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
595495007894	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
595495007895	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
595495007896	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
595495007897	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
595495007898	NAD binding site [chemical binding]; other site
595495007899	homodimer interface [polypeptide binding]; other site
595495007900	active site
595495007901	substrate binding site [chemical binding]; other site
595495007902	sugar transferase, PEP-CTERM/EpsH1 system associated; Region: stp1; TIGR03087
595495007903	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
595495007904	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
595495007905	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
595495007906	Substrate binding site; other site
595495007907	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
595495007908	phosphomannomutase CpsG; Provisional; Region: PRK15414
595495007909	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
595495007910	active site
595495007911	substrate binding site [chemical binding]; other site
595495007912	metal binding site [ion binding]; metal-binding site
595495007913	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
595495007914	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
595495007915	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
595495007916	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
595495007917	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
595495007918	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
595495007919	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
595495007920	chain length determinant protein WzzB; Provisional; Region: PRK15471
595495007921	Chain length determinant protein; Region: Wzz; pfam02706
595495007922	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
595495007923	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
595495007924	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
595495007925	metal binding site [ion binding]; metal-binding site
595495007926	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
595495007927	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
595495007928	substrate binding site [chemical binding]; other site
595495007929	glutamase interaction surface [polypeptide binding]; other site
595495007930	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
595495007931	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
595495007932	catalytic residues [active]
595495007933	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
595495007934	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
595495007935	putative active site [active]
595495007936	oxyanion strand; other site
595495007937	catalytic triad [active]
595495007938	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
595495007939	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495007940	active site
595495007941	motif I; other site
595495007942	motif II; other site
595495007943	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
595495007944	putative active site pocket [active]
595495007945	4-fold oligomerization interface [polypeptide binding]; other site
595495007946	metal binding residues [ion binding]; metal-binding site
595495007947	3-fold/trimer interface [polypeptide binding]; other site
595495007948	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
595495007949	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
595495007950	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495007951	homodimer interface [polypeptide binding]; other site
595495007952	catalytic residue [active]
595495007953	Histidinol dehydrogenase; Region: Histidinol_dh; pfam00815
595495007954	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
595495007955	NAD binding site [chemical binding]; other site
595495007956	dimerization interface [polypeptide binding]; other site
595495007957	product binding site; other site
595495007958	substrate binding site [chemical binding]; other site
595495007959	zinc binding site [ion binding]; other site
595495007960	catalytic residues [active]
595495007961	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
595495007962	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
595495007963	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
595495007964	antitoxin YefM; Provisional; Region: PRK11409
595495007965	Plasmid encoded toxin Txe; Region: Plasmid_Txe; pfam06769
595495007966	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
595495007967	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
595495007968	putative NAD(P) binding site [chemical binding]; other site
595495007969	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495007970	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
595495007971	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
595495007972	dimerization interface [polypeptide binding]; other site
595495007973	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
595495007974	putative selenium metabolism protein, YedE family; Region: seleno_YedE; TIGR04112
595495007975	Sulphur transport; Region: Sulf_transp; pfam04143
595495007976	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
595495007977	CPxP  motif; other site
595495007978	exonuclease I; Provisional; Region: sbcB; PRK11779
595495007979	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
595495007980	active site
595495007981	catalytic site [active]
595495007982	substrate binding site [chemical binding]; other site
595495007983	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
595495007984	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
595495007985	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
595495007986	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
595495007987	DNA gyrase inhibitor; Provisional; Region: PRK10016
595495007988	Predicted membrane protein [Function unknown]; Region: COG1289
595495007989	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
595495007990	hypothetical protein; Provisional; Region: PRK05423
595495007991	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
595495007992	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
595495007993	homotrimer interface [polypeptide binding]; other site
595495007994	Walker A motif; other site
595495007995	GTP binding site [chemical binding]; other site
595495007996	Walker B motif; other site
595495007997	cobalamin 5'-phosphate synthase/cobalamin synthase; Region: cobS; TIGR00317
595495007998	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
595495007999	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
595495008000	putative dimer interface [polypeptide binding]; other site
595495008001	active site pocket [active]
595495008002	putative cataytic base [active]
595495008003	L,D-transpeptidase; Provisional; Region: PRK10190
595495008004	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
595495008005	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
595495008006	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495008007	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
595495008008	putative dimerization interface [polypeptide binding]; other site
595495008009	transcriptional regulator Cbl; Reviewed; Region: cbl; PRK12679
595495008010	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495008011	The C-terminal substrate binding domain of LysR-type transcriptional regulator Cbl, which is required for expression of sulfate starvation-inducible (ssi) genes, contains the type 2 periplasmic binding fold; Region: PBP2_Cbl; cd08444
595495008012	putative substrate binding site [chemical binding]; other site
595495008013	dimerization interface [polypeptide binding]; other site
595495008014	MATE family multidrug exporter; Provisional; Region: PRK10189
595495008015	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
595495008016	Transcriptional regulator; Region: Transcrip_reg; cl00361
595495008017	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495008018	hypothetical protein; Provisional; Region: PRK12378
595495008019	AMP nucleosidase; Provisional; Region: PRK08292
595495008020	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
595495008021	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
595495008022	shikimate transporter; Provisional; Region: PRK09952
595495008023	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495008024	putative substrate translocation pore; other site
595495008025	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
595495008026	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
595495008027	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
595495008028	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
595495008029	zinc/cadmium-binding protein; Provisional; Region: PRK10306
595495008030	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
595495008031	TMAO/DMSO reductase; Reviewed; Region: PRK05363
595495008032	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
595495008033	Moco binding site; other site
595495008034	metal coordination site [ion binding]; other site
595495008035	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
595495008036	active site
595495008037	homotetramer interface [polypeptide binding]; other site
595495008038	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
595495008039	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495008040	active site
595495008041	phosphorylation site [posttranslational modification]
595495008042	intermolecular recognition site; other site
595495008043	dimerization interface [polypeptide binding]; other site
595495008044	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
595495008045	DNA binding site [nucleotide binding]
595495008046	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
595495008047	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
595495008048	dimer interface [polypeptide binding]; other site
595495008049	phosphorylation site [posttranslational modification]
595495008050	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495008051	ATP binding site [chemical binding]; other site
595495008052	Mg2+ binding site [ion binding]; other site
595495008053	G-X-G motif; other site
595495008054	chaperone protein HchA; Provisional; Region: PRK04155
595495008055	Type 1 glutamine amidotransferase (GATase1)-like domain found in Escherichia coli Hsp31 protein (EcHsp31); Region: GATase1_EcHsp31_like; cd03148
595495008056	dimer interface [polypeptide binding]; other site
595495008057	metal binding site [ion binding]; metal-binding site
595495008058	potential oxyanion hole; other site
595495008059	potential catalytic triad [active]
595495008060	conserved cys residue [active]
595495008061	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
595495008062	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
595495008063	eyelet of channel; other site
595495008064	trimer interface [polypeptide binding]; other site
595495008065	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
595495008066	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
595495008067	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
595495008068	Zn2+ binding site [ion binding]; other site
595495008069	Mg2+ binding site [ion binding]; other site
595495008070	DNA cytosine methylase; Provisional; Region: PRK10458
595495008071	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
595495008072	cofactor binding site; other site
595495008073	DNA binding site [nucleotide binding]
595495008074	substrate interaction site [chemical binding]; other site
595495008075	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
595495008076	additional DNA contacts [nucleotide binding]; other site
595495008077	mismatch recognition site; other site
595495008078	active site
595495008079	zinc binding site [ion binding]; other site
595495008080	DNA intercalation site [nucleotide binding]; other site
595495008081	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
595495008082	EamA-like transporter family; Region: EamA; pfam00892
595495008083	hypothetical protein; Provisional; Region: PRK10062
595495008084	Uncharacterized small protein [Function unknown]; Region: COG5475
595495008085	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
595495008086	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
595495008087	metal binding site [ion binding]; metal-binding site
595495008088	active site
595495008089	I-site; other site
595495008090	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
595495008091	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495008092	active site
595495008093	motif I; other site
595495008094	motif II; other site
595495008095	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
595495008096	hypothetical protein; Provisional; Region: PRK10708
595495008097	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
595495008098	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
595495008099	DNA binding residues [nucleotide binding]
595495008100	dimerization interface [polypeptide binding]; other site
595495008101	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
595495008102	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
595495008103	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
595495008104	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
595495008105	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
595495008106	flagellar motor switch protein; Validated; Region: fliN; PRK05698
595495008107	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
595495008108	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
595495008109	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
595495008110	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
595495008111	flagellar hook-length control protein; Provisional; Region: PRK10118
595495008112	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
595495008113	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
595495008114	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
595495008115	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
595495008116	Walker A motif/ATP binding site; other site
595495008117	Walker B motif; other site
595495008118	flagellar assembly protein H; Validated; Region: fliH; PRK05687
595495008119	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
595495008120	Flagellar assembly protein FliH; Region: FliH; pfam02108
595495008121	flagellar motor switch protein FliG; Region: fliG; TIGR00207
595495008122	FliG C-terminal domain; Region: FliG_C; pfam01706
595495008123	flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); Region: fliF; TIGR00206
595495008124	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
595495008125	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
595495008126	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
595495008127	multidrug efflux protein; Reviewed; Region: emrE; PRK09541
595495008128	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
595495008129	substrate binding site [chemical binding]; other site
595495008130	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
595495008131	Transposase IS200 like; Region: Y1_Tnp; pfam01797
595495008132	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
595495008133	Probable transposase; Region: OrfB_IS605; pfam01385
595495008134	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
595495008135	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
595495008136	Uncharacterized ACR, COG2135; Region: DUF159; cl03646
595495008137	Uncharacterized ACR, COG2135; Region: DUF159; cl03646
595495008138	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
595495008139	CPxP  motif; other site
595495008140	putative inner membrane protein; Provisional; Region: PRK11099
595495008141	lipoprotein; Provisional; Region: PRK10397
595495008142	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
595495008143	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
595495008144	active site
595495008145	Na/Ca binding site [ion binding]; other site
595495008146	catalytic site [active]
595495008147	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
595495008148	Flagellar protein FliS; Region: FliS; cl00654
595495008149	flagellar capping protein; Reviewed; Region: fliD; PRK08032
595495008150	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
595495008151	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
595495008152	flagellin; Validated; Region: PRK08026
595495008153	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
595495008154	Flagellin protein; Region: FliC; pfam12445
595495008155	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
595495008156	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
595495008157	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
595495008158	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
595495008159	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
595495008160	DNA binding residues [nucleotide binding]
595495008161	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
595495008162	cystine transporter subunit; Provisional; Region: PRK11260
595495008163	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
595495008164	substrate binding pocket [chemical binding]; other site
595495008165	membrane-bound complex binding site; other site
595495008166	hinge residues; other site
595495008167	D-cysteine desulfhydrase; Validated; Region: PRK03910
595495008168	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
595495008169	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495008170	catalytic residue [active]
595495008171	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
595495008172	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495008173	dimer interface [polypeptide binding]; other site
595495008174	conserved gate region; other site
595495008175	putative PBP binding loops; other site
595495008176	ABC-ATPase subunit interface; other site
595495008177	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
595495008178	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
595495008179	Walker A/P-loop; other site
595495008180	ATP binding site [chemical binding]; other site
595495008181	Q-loop/lid; other site
595495008182	ABC transporter signature motif; other site
595495008183	Walker B; other site
595495008184	D-loop; other site
595495008185	H-loop/switch region; other site
595495008186	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
595495008187	Autoinducer binding domain; Region: Autoind_bind; pfam03472
595495008188	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
595495008189	DNA binding residues [nucleotide binding]
595495008190	dimerization interface [polypeptide binding]; other site
595495008191	hypothetical protein; Provisional; Region: PRK10613
595495008192	response regulator; Provisional; Region: PRK09483
595495008193	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495008194	active site
595495008195	phosphorylation site [posttranslational modification]
595495008196	intermolecular recognition site; other site
595495008197	dimerization interface [polypeptide binding]; other site
595495008198	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
595495008199	DNA binding residues [nucleotide binding]
595495008200	dimerization interface [polypeptide binding]; other site
595495008201	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
595495008202	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
595495008203	GIY-YIG motif/motif A; other site
595495008204	active site
595495008205	catalytic site [active]
595495008206	putative DNA binding site [nucleotide binding]; other site
595495008207	metal binding site [ion binding]; metal-binding site
595495008208	UvrB/uvrC motif; Region: UVR; pfam02151
595495008209	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
595495008210	Helix-hairpin-helix motif; Region: HHH; pfam00633
595495008211	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
595495008212	hypothetical protein; Provisional; Region: PRK10396
595495008213	yecA family protein; Region: ygfB_yecA; TIGR02292
595495008214	SEC-C motif; Region: SEC-C; pfam02810
595495008215	tyrosine transporter TyrP; Provisional; Region: PRK15132
595495008216	aromatic amino acid transport protein; Region: araaP; TIGR00837
595495008217	probable metal-binding protein; Region: matur_matur; TIGR03853
595495008218	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
595495008219	Ferritin-like domain; Region: Ferritin; pfam00210
595495008220	ferroxidase diiron center [ion binding]; other site
595495008221	YecR-like lipoprotein; Region: YecR; pfam13992
595495008222	Protein of unknown function (DUF2766); Region: DUF2766; pfam10964
595495008223	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
595495008224	Ferritin-like domain; Region: Ferritin; pfam00210
595495008225	ferroxidase diiron center [ion binding]; other site
595495008226	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
595495008227	Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540
595495008228	ligand binding site [chemical binding]; other site
595495008229	L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288
595495008230	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
595495008231	Walker A/P-loop; other site
595495008232	ATP binding site [chemical binding]; other site
595495008233	Q-loop/lid; other site
595495008234	ABC transporter signature motif; other site
595495008235	Walker B; other site
595495008236	D-loop; other site
595495008237	H-loop/switch region; other site
595495008238	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
595495008239	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
595495008240	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
595495008241	TM-ABC transporter signature motif; other site
595495008242	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
595495008243	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
595495008244	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
595495008245	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
595495008246	active site
595495008247	homotetramer interface [polypeptide binding]; other site
595495008248	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
595495008249	Ligand Binding Site [chemical binding]; other site
595495008250	transcriptional activator FlhD; Provisional; Region: PRK02909
595495008251	transcriptional activator FlhC; Provisional; Region: PRK12722
595495008252	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
595495008253	flagellar motor protein MotA; Validated; Region: PRK09110
595495008254	flagellar motor protein MotB; Validated; Region: motB; PRK09041
595495008255	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
595495008256	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
595495008257	ligand binding site [chemical binding]; other site
595495008258	chemotaxis protein CheA; Provisional; Region: PRK10547
595495008259	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
595495008260	putative binding surface; other site
595495008261	active site
595495008262	CheY binding; Region: CheY-binding; pfam09078
595495008263	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
595495008264	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495008265	ATP binding site [chemical binding]; other site
595495008266	Mg2+ binding site [ion binding]; other site
595495008267	G-X-G motif; other site
595495008268	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
595495008269	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
595495008270	putative CheA interaction surface; other site
595495008271	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
595495008272	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
595495008273	dimer interface [polypeptide binding]; other site
595495008274	ligand binding site [chemical binding]; other site
595495008275	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
595495008276	dimerization interface [polypeptide binding]; other site
595495008277	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
595495008278	dimer interface [polypeptide binding]; other site
595495008279	putative CheW interface [polypeptide binding]; other site
595495008280	methyl-accepting protein IV; Provisional; Region: PRK09793
595495008281	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
595495008282	dimer interface [polypeptide binding]; other site
595495008283	ligand binding site [chemical binding]; other site
595495008284	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
595495008285	dimerization interface [polypeptide binding]; other site
595495008286	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
595495008287	dimer interface [polypeptide binding]; other site
595495008288	putative CheW interface [polypeptide binding]; other site
595495008289	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
595495008290	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
595495008291	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495008292	S-adenosylmethionine binding site [chemical binding]; other site
595495008293	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
595495008294	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495008295	active site
595495008296	phosphorylation site [posttranslational modification]
595495008297	intermolecular recognition site; other site
595495008298	dimerization interface [polypeptide binding]; other site
595495008299	CheB methylesterase; Region: CheB_methylest; pfam01339
595495008300	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
595495008301	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495008302	active site
595495008303	phosphorylation site [posttranslational modification]
595495008304	intermolecular recognition site; other site
595495008305	dimerization interface [polypeptide binding]; other site
595495008306	chemotaxis regulator CheZ; Provisional; Region: PRK11166
595495008307	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
595495008308	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
595495008309	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
595495008310	FHIPEP family; Region: FHIPEP; pfam00771
595495008311	Flagellar protein FlhE; Region: FlhE; pfam06366
595495008312	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
595495008313	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
595495008314	arginyl-tRNA synthetase; Region: argS; TIGR00456
595495008315	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
595495008316	active site
595495008317	HIGH motif; other site
595495008318	KMSK motif region; other site
595495008319	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
595495008320	tRNA binding surface [nucleotide binding]; other site
595495008321	anticodon binding site; other site
595495008322	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
595495008323	putative metal binding site [ion binding]; other site
595495008324	copper homeostasis protein CutC; Provisional; Region: PRK11572
595495008325	trimethylamine-N-oxide reductase c-type cytochrome TorC; Region: torC; TIGR02162
595495008326	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
595495008327	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
595495008328	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
595495008329	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
595495008330	molybdopterin cofactor binding site [chemical binding]; other site
595495008331	substrate binding site [chemical binding]; other site
595495008332	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
595495008333	molybdopterin cofactor binding site; other site
595495008334	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495008335	S-adenosylmethionine binding site [chemical binding]; other site
595495008336	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495008337	S-adenosylmethionine binding site [chemical binding]; other site
595495008338	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
595495008339	hypothetical protein; Provisional; Region: PRK10302
595495008340	Isochorismatase family; Region: Isochorismatase; pfam00857
595495008341	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
595495008342	catalytic triad [active]
595495008343	conserved cis-peptide bond; other site
595495008344	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
595495008345	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
595495008346	dimer interface [polypeptide binding]; other site
595495008347	anticodon binding site; other site
595495008348	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
595495008349	homodimer interface [polypeptide binding]; other site
595495008350	motif 1; other site
595495008351	active site
595495008352	motif 2; other site
595495008353	GAD domain; Region: GAD; pfam02938
595495008354	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
595495008355	motif 3; other site
595495008356	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
595495008357	nudix motif; other site
595495008358	hypothetical protein; Validated; Region: PRK00110
595495008359	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
595495008360	active site
595495008361	putative DNA-binding cleft [nucleotide binding]; other site
595495008362	dimer interface [polypeptide binding]; other site
595495008363	hypothetical protein; Provisional; Region: PRK11470
595495008364	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
595495008365	RuvA N terminal domain; Region: RuvA_N; pfam01330
595495008366	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
595495008367	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
595495008368	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495008369	Walker A motif; other site
595495008370	ATP binding site [chemical binding]; other site
595495008371	Walker B motif; other site
595495008372	arginine finger; other site
595495008373	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
595495008374	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
595495008375	Transposase; Region: DEDD_Tnp_IS110; pfam01548
595495008376	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
595495008377	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
595495008378	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
595495008379	ABC-ATPase subunit  interface; other site
595495008380	dimer interface [polypeptide binding]; other site
595495008381	putative PBP binding regions; other site
595495008382	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
595495008383	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
595495008384	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
595495008385	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
595495008386	metal binding site [ion binding]; metal-binding site
595495008387	putative peptidase; Provisional; Region: PRK11649
595495008388	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
595495008389	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
595495008390	Peptidase family M23; Region: Peptidase_M23; pfam01551
595495008391	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
595495008392	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
595495008393	putative acyl-acceptor binding pocket; other site
595495008394	pyruvate kinase; Provisional; Region: PRK05826
595495008395	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
595495008396	domain interfaces; other site
595495008397	active site
595495008398	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
595495008399	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
595495008400	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
595495008401	putative active site [active]
595495008402	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
595495008403	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
595495008404	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
595495008405	phosphogluconate dehydratase; Validated; Region: PRK09054
595495008406	6-phosphogluconate dehydratase; Region: edd; TIGR01196
595495008407	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
595495008408	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
595495008409	active site
595495008410	intersubunit interface [polypeptide binding]; other site
595495008411	catalytic residue [active]
595495008412	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
595495008413	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
595495008414	ATP-grasp domain; Region: ATP-grasp; pfam02222
595495008415	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
595495008416	hypothetical protein; Provisional; Region: PRK13680
595495008417	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
595495008418	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
595495008419	putative metal binding site [ion binding]; other site
595495008420	protease 2; Provisional; Region: PRK10115
595495008421	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
595495008422	exodeoxyribonuclease X; Provisional; Region: PRK07983
595495008423	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
595495008424	active site
595495008425	catalytic site [active]
595495008426	substrate binding site [chemical binding]; other site
595495008427	Predicted amidohydrolase [General function prediction only]; Region: COG0388
595495008428	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
595495008429	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
595495008430	hypothetical protein; Provisional; Region: PRK10301
595495008431	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
595495008432	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
595495008433	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
595495008434	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
595495008435	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
595495008436	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
595495008437	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
595495008438	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495008439	S-adenosylmethionine binding site [chemical binding]; other site
595495008440	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
595495008441	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
595495008442	mce related protein; Region: MCE; pfam02470
595495008443	mce related protein; Region: MCE; pfam02470
595495008444	mce related protein; Region: MCE; pfam02470
595495008445	mce related protein; Region: MCE; pfam02470
595495008446	mce related protein; Region: MCE; pfam02470
595495008447	integral membrane protein, PqiA family; Region: pqiA_fam; TIGR00155
595495008448	Paraquat-inducible protein A; Region: PqiA; pfam04403
595495008449	Paraquat-inducible protein A; Region: PqiA; pfam04403
595495008450	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
595495008451	GAF domain; Region: GAF_2; pfam13185
595495008452	ProP expression regulator; Provisional; Region: PRK04950
595495008453	ProQ/FINO family; Region: ProQ; pfam04352
595495008454	carboxy-terminal protease; Provisional; Region: PRK11186
595495008455	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
595495008456	protein binding site [polypeptide binding]; other site
595495008457	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
595495008458	Catalytic dyad [active]
595495008459	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
595495008460	heat shock protein HtpX; Provisional; Region: PRK05457
595495008461	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495008462	Major Facilitator Superfamily; Region: MFS_1; pfam07690
595495008463	putative substrate translocation pore; other site
595495008464	Predicted integral membrane protein [Function unknown]; Region: COG5521
595495008465	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
595495008466	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
595495008467	dimerization interface [polypeptide binding]; other site
595495008468	putative Zn2+ binding site [ion binding]; other site
595495008469	putative DNA binding site [nucleotide binding]; other site
595495008470	Bacterial transcriptional regulator; Region: IclR; pfam01614
595495008471	PhoPQ regulatory protein; Provisional; Region: PRK10299
595495008472	YebO-like protein; Region: YebO; pfam13974
595495008473	Protein of unknown function (DUF2627); Region: DUF2527; pfam10736
595495008474	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
595495008475	DNA-binding site [nucleotide binding]; DNA binding site
595495008476	RNA-binding motif; other site
595495008477	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
595495008478	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495008479	S-adenosylmethionine binding site [chemical binding]; other site
595495008480	hypothetical protein; Provisional; Region: PRK11469
595495008481	Domain of unknown function DUF; Region: DUF204; pfam02659
595495008482	Domain of unknown function DUF; Region: DUF204; pfam02659
595495008483	Predicted membrane protein [Function unknown]; Region: COG4811
595495008484	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
595495008485	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
595495008486	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
595495008487	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
595495008488	active pocket/dimerization site; other site
595495008489	active site
595495008490	phosphorylation site [posttranslational modification]
595495008491	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
595495008492	active site
595495008493	phosphorylation site [posttranslational modification]
595495008494	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
595495008495	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
595495008496	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
595495008497	Transporter associated domain; Region: CorC_HlyC; smart01091
595495008498	phage resistance protein; Provisional; Region: PRK10551
595495008499	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
595495008500	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
595495008501	L-serine deaminase; Provisional; Region: PRK15023
595495008502	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
595495008503	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
595495008504	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
595495008505	putative active site [active]
595495008506	putative CoA binding site [chemical binding]; other site
595495008507	nudix motif; other site
595495008508	metal binding site [ion binding]; metal-binding site
595495008509	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
595495008510	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
595495008511	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
595495008512	hypothetical protein; Provisional; Region: PRK05114
595495008513	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
595495008514	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
595495008515	homotrimer interaction site [polypeptide binding]; other site
595495008516	putative active site [active]
595495008517	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
595495008518	DEAD/DEAH box helicase; Region: DEAD; pfam00270
595495008519	DEAD_2; Region: DEAD_2; pfam06733
595495008520	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
595495008521	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
595495008522	Glycoprotease family; Region: Peptidase_M22; pfam00814
595495008523	outer membrane lipoprotein, Slp family; Region: slp; TIGR00752
595495008524	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
595495008525	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
595495008526	acyl-activating enzyme (AAE) consensus motif; other site
595495008527	putative AMP binding site [chemical binding]; other site
595495008528	putative active site [active]
595495008529	putative CoA binding site [chemical binding]; other site
595495008530	ribonuclease D; Provisional; Region: PRK10829
595495008531	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
595495008532	catalytic site [active]
595495008533	putative active site [active]
595495008534	putative substrate binding site [chemical binding]; other site
595495008535	Helicase and RNase D C-terminal; Region: HRDC; smart00341
595495008536	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
595495008537	Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal  ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185
595495008538	FMN-binding pocket [chemical binding]; other site
595495008539	flavin binding motif; other site
595495008540	phosphate binding motif [ion binding]; other site
595495008541	beta-alpha-beta structure motif; other site
595495008542	NAD binding pocket [chemical binding]; other site
595495008543	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
595495008544	catalytic loop [active]
595495008545	iron binding site [ion binding]; other site
595495008546	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
595495008547	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
595495008548	[2Fe-2S] cluster binding site [ion binding]; other site
595495008549	C-terminal catalytic domain of the oxygenase alpha subunit of an uncharacterized subgroup of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases; Region: RHO_alpha_C_2; cd08886
595495008550	putative alpha subunit interface [polypeptide binding]; other site
595495008551	putative active site [active]
595495008552	putative substrate binding site [chemical binding]; other site
595495008553	Fe binding site [ion binding]; other site
595495008554	putative transporter; Provisional; Region: PRK09950
595495008555	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
595495008556	tartrate dehydrogenase; Region: TTC; TIGR02089
595495008557	transcriptional activator TtdR; Provisional; Region: PRK09801
595495008558	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495008559	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
595495008560	putative effector binding pocket; other site
595495008561	putative dimerization interface [polypeptide binding]; other site
595495008562	leucine export protein LeuE; Provisional; Region: PRK10958
595495008563	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
595495008564	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
595495008565	Transposase IS200 like; Region: Y1_Tnp; pfam01797
595495008566	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
595495008567	Probable transposase; Region: OrfB_IS605; pfam01385
595495008568	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
595495008569	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
595495008570	hypothetical protein; Provisional; Region: PRK10457
595495008571	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
595495008572	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
595495008573	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
595495008574	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
595495008575	metal binding site [ion binding]; metal-binding site
595495008576	active site
595495008577	I-site; other site
595495008578	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
595495008579	Domain of unknown function (DUF333); Region: DUF333; pfam03891
595495008580	Uncharacterized conserved protein [Function unknown]; Region: COG3189
595495008581	cyanate transporter; Region: CynX; TIGR00896
595495008582	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495008583	putative substrate translocation pore; other site
595495008584	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
595495008585	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495008586	Predicted membrane protein [Function unknown]; Region: COG2707
595495008587	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
595495008588	putative deacylase active site [active]
595495008589	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
595495008590	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
595495008591	metal binding site [ion binding]; metal-binding site
595495008592	active site
595495008593	I-site; other site
595495008594	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
595495008595	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
595495008596	metal binding site [ion binding]; metal-binding site
595495008597	active site
595495008598	I-site; other site
595495008599	hypothetical protein; Provisional; Region: PRK05325
595495008600	PrkA family serine protein kinase; Provisional; Region: PRK15455
595495008601	AAA ATPase domain; Region: AAA_16; pfam13191
595495008602	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
595495008603	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
595495008604	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
595495008605	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
595495008606	active site
595495008607	catalytic tetrad [active]
595495008608	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
595495008609	active site
595495008610	phosphate binding residues; other site
595495008611	catalytic residues [active]
595495008612	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
595495008613	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
595495008614	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
595495008615	methionine sulfoxide reductase B; Provisional; Region: PRK00222
595495008616	SelR domain; Region: SelR; pfam01641
595495008617	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
595495008618	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
595495008619	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
595495008620	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
595495008621	NAD(P) binding site [chemical binding]; other site
595495008622	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495008623	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495008624	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
595495008625	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
595495008626	inhibitor binding site; inhibition site
595495008627	catalytic Zn binding site [ion binding]; other site
595495008628	structural Zn binding site [ion binding]; other site
595495008629	NADP binding site [chemical binding]; other site
595495008630	tetramer interface [polypeptide binding]; other site
595495008631	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
595495008632	intersubunit interface [polypeptide binding]; other site
595495008633	active site
595495008634	zinc binding site [ion binding]; other site
595495008635	Na+ binding site [ion binding]; other site
595495008636	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
595495008637	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
595495008638	substrate binding site [chemical binding]; other site
595495008639	ATP binding site [chemical binding]; other site
595495008640	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
595495008641	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
595495008642	active site
595495008643	catalytic tetrad [active]
595495008644	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
595495008645	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
595495008646	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
595495008647	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
595495008648	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495008649	putative substrate translocation pore; other site
595495008650	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495008651	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
595495008652	Isochorismatase family; Region: Isochorismatase; pfam00857
595495008653	catalytic triad [active]
595495008654	metal binding site [ion binding]; metal-binding site
595495008655	conserved cis-peptide bond; other site
595495008656	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
595495008657	active site
595495008658	homodimer interface [polypeptide binding]; other site
595495008659	protease 4; Provisional; Region: PRK10949
595495008660	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
595495008661	tandem repeat interface [polypeptide binding]; other site
595495008662	oligomer interface [polypeptide binding]; other site
595495008663	active site residues [active]
595495008664	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
595495008665	tandem repeat interface [polypeptide binding]; other site
595495008666	oligomer interface [polypeptide binding]; other site
595495008667	active site residues [active]
595495008668	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
595495008669	putative FMN binding site [chemical binding]; other site
595495008670	selenophosphate synthetase; Provisional; Region: PRK00943
595495008671	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
595495008672	dimerization interface [polypeptide binding]; other site
595495008673	putative ATP binding site [chemical binding]; other site
595495008674	DNA topoisomerase III; Provisional; Region: PRK07726
595495008675	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
595495008676	active site
595495008677	putative interdomain interaction site [polypeptide binding]; other site
595495008678	putative metal-binding site [ion binding]; other site
595495008679	putative nucleotide binding site [chemical binding]; other site
595495008680	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
595495008681	domain I; other site
595495008682	DNA binding groove [nucleotide binding]
595495008683	phosphate binding site [ion binding]; other site
595495008684	domain II; other site
595495008685	domain III; other site
595495008686	nucleotide binding site [chemical binding]; other site
595495008687	catalytic site [active]
595495008688	domain IV; other site
595495008689	hypothetical protein; Provisional; Region: PRK11380
595495008690	glutamate dehydrogenase; Provisional; Region: PRK09414
595495008691	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
595495008692	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
595495008693	NAD(P) binding site [chemical binding]; other site
595495008694	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
595495008695	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
595495008696	active site
595495008697	8-oxo-dGMP binding site [chemical binding]; other site
595495008698	nudix motif; other site
595495008699	metal binding site [ion binding]; metal-binding site
595495008700	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
595495008701	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4136
595495008702	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495008703	Walker A/P-loop; other site
595495008704	ATP binding site [chemical binding]; other site
595495008705	Q-loop/lid; other site
595495008706	ABC transporter signature motif; other site
595495008707	Walker B; other site
595495008708	D-loop; other site
595495008709	H-loop/switch region; other site
595495008710	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4135
595495008711	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495008712	dimer interface [polypeptide binding]; other site
595495008713	conserved gate region; other site
595495008714	putative PBP binding loops; other site
595495008715	ABC-ATPase subunit interface; other site
595495008716	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4134
595495008717	hypothetical protein; Provisional; Region: PRK11622
595495008718	Uncharacterized conserved protein [Function unknown]; Region: COG2128
595495008719	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
595495008720	Uncharacterized conserved protein [Function unknown]; Region: COG0398
595495008721	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
595495008722	Uncharacterized conserved protein [Function unknown]; Region: COG0398
595495008723	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
595495008724	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
595495008725	putative catalytic site [active]
595495008726	putative phosphate binding site [ion binding]; other site
595495008727	active site
595495008728	metal binding site A [ion binding]; metal-binding site
595495008729	DNA binding site [nucleotide binding]
595495008730	putative AP binding site [nucleotide binding]; other site
595495008731	putative metal binding site B [ion binding]; other site
595495008732	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
595495008733	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
595495008734	inhibitor-cofactor binding pocket; inhibition site
595495008735	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495008736	catalytic residue [active]
595495008737	arginine succinyltransferase; Provisional; Region: PRK10456
595495008738	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
595495008739	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
595495008740	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
595495008741	NAD(P) binding site [chemical binding]; other site
595495008742	catalytic residues [active]
595495008743	succinylarginine dihydrolase; Provisional; Region: PRK13281
595495008744	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
595495008745	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
595495008746	putative active site [active]
595495008747	Zn binding site [ion binding]; other site
595495008748	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
595495008749	dimer interface [polypeptide binding]; other site
595495008750	hypothetical protein; Provisional; Region: PRK11396
595495008751	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
595495008752	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
595495008753	GIY-YIG motif/motif A; other site
595495008754	active site
595495008755	catalytic site [active]
595495008756	putative DNA binding site [nucleotide binding]; other site
595495008757	metal binding site [ion binding]; metal-binding site
595495008758	NAD+ synthetase; Region: nadE; TIGR00552
595495008759	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
595495008760	homodimer interface [polypeptide binding]; other site
595495008761	NAD binding pocket [chemical binding]; other site
595495008762	ATP binding pocket [chemical binding]; other site
595495008763	Mg binding site [ion binding]; other site
595495008764	active-site loop [active]
595495008765	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
595495008766	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
595495008767	active site
595495008768	P-loop; other site
595495008769	phosphorylation site [posttranslational modification]
595495008770	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
595495008771	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
595495008772	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
595495008773	methionine cluster; other site
595495008774	active site
595495008775	phosphorylation site [posttranslational modification]
595495008776	metal binding site [ion binding]; metal-binding site
595495008777	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
595495008778	Cupin domain; Region: Cupin_2; pfam07883
595495008779	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495008780	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
595495008781	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
595495008782	NAD binding site [chemical binding]; other site
595495008783	sugar binding site [chemical binding]; other site
595495008784	divalent metal binding site [ion binding]; other site
595495008785	tetramer (dimer of dimers) interface [polypeptide binding]; other site
595495008786	dimer interface [polypeptide binding]; other site
595495008787	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
595495008788	putative active site [active]
595495008789	YdjC motif; other site
595495008790	Mg binding site [ion binding]; other site
595495008791	putative homodimer interface [polypeptide binding]; other site
595495008792	hydroperoxidase II; Provisional; Region: katE; PRK11249
595495008793	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
595495008794	tetramer interface [polypeptide binding]; other site
595495008795	heme binding pocket [chemical binding]; other site
595495008796	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
595495008797	domain interactions; other site
595495008798	cell division modulator; Provisional; Region: PRK10113
595495008799	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
595495008800	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
595495008801	inner membrane protein; Provisional; Region: PRK11648
595495008802	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
595495008803	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
595495008804	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495008805	motif II; other site
595495008806	YniB-like protein; Region: YniB; pfam14002
595495008807	Phosphotransferase enzyme family; Region: APH; pfam01636
595495008808	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
595495008809	active site
595495008810	ATP binding site [chemical binding]; other site
595495008811	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
595495008812	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
595495008813	6-phosphofructokinase 2; Provisional; Region: PRK10294
595495008814	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
595495008815	putative substrate binding site [chemical binding]; other site
595495008816	putative ATP binding site [chemical binding]; other site
595495008817	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
595495008818	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495008819	potential frameshift: common BLAST hit: gi|218705219|ref|YP_002412738.1| putative ankyrin repeat regulatory protein
595495008820	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
595495008821	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
595495008822	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
595495008823	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
595495008824	active site
595495008825	dimer interface [polypeptide binding]; other site
595495008826	motif 1; other site
595495008827	motif 2; other site
595495008828	motif 3; other site
595495008829	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
595495008830	anticodon binding site; other site
595495008831	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
595495008832	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
595495008833	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
595495008834	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
595495008835	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
595495008836	23S rRNA binding site [nucleotide binding]; other site
595495008837	L21 binding site [polypeptide binding]; other site
595495008838	L13 binding site [polypeptide binding]; other site
595495008839	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
595495008840	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
595495008841	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
595495008842	dimer interface [polypeptide binding]; other site
595495008843	motif 1; other site
595495008844	active site
595495008845	motif 2; other site
595495008846	motif 3; other site
595495008847	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
595495008848	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
595495008849	putative tRNA-binding site [nucleotide binding]; other site
595495008850	B3/4 domain; Region: B3_4; pfam03483
595495008851	tRNA synthetase B5 domain; Region: B5; smart00874
595495008852	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
595495008853	dimer interface [polypeptide binding]; other site
595495008854	motif 1; other site
595495008855	motif 3; other site
595495008856	motif 2; other site
595495008857	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
595495008858	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
595495008859	IHF dimer interface [polypeptide binding]; other site
595495008860	IHF - DNA interface [nucleotide binding]; other site
595495008861	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
595495008862	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
595495008863	ABC-ATPase subunit  interface; other site
595495008864	dimer interface [polypeptide binding]; other site
595495008865	putative PBP binding regions; other site
595495008866	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
595495008867	catalytic residues [active]
595495008868	dimer interface [polypeptide binding]; other site
595495008869	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
595495008870	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
595495008871	Walker A/P-loop; other site
595495008872	ATP binding site [chemical binding]; other site
595495008873	Q-loop/lid; other site
595495008874	ABC transporter signature motif; other site
595495008875	Walker B; other site
595495008876	D-loop; other site
595495008877	H-loop/switch region; other site
595495008878	NlpC/P60 family; Region: NLPC_P60; pfam00877
595495008879	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
595495008880	Uncharacterized conserved protein [Function unknown]; Region: COG0397
595495008881	hypothetical protein; Validated; Region: PRK00029
595495008882	Hemin uptake protein [Inorganic ion transport and metabolism]; Region: HemP; COG4256
595495008883	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
595495008884	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
595495008885	PEP synthetase regulatory protein; Provisional; Region: PRK05339
595495008886	phosphoenolpyruvate synthase; Validated; Region: PRK06464
595495008887	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
595495008888	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
595495008889	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
595495008890	short chain acyl-CoA synthetase; Reviewed; Region: PRK06087
595495008891	Cyclohexanecarboxylate-CoA ligase (also called cyclohex-1-ene-1-carboxylate:CoA ligase); Region: CHC_CoA_lg; cd05903
595495008892	acyl-activating enzyme (AAE) consensus motif; other site
595495008893	putative AMP binding site [chemical binding]; other site
595495008894	putative active site [active]
595495008895	putative CoA binding site [chemical binding]; other site
595495008896	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
595495008897	oxidoreductase; Provisional; Region: PRK10015
595495008898	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
595495008899	Electron transfer flavoprotein domain; Region: ETF; smart00893
595495008900	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
595495008901	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
595495008902	Ligand binding site [chemical binding]; other site
595495008903	Electron transfer flavoprotein domain; Region: ETF; pfam01012
595495008904	Cupin domain; Region: Cupin_2; pfam07883
595495008905	Winged helix DNA-binding domain (DUF1495); Region: DUF1495; cl01336
595495008906	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
595495008907	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495008908	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
595495008909	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
595495008910	active site
595495008911	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
595495008912	Coenzyme A transferase; Region: CoA_trans; smart00882
595495008913	Coenzyme A transferase; Region: CoA_trans; cl17247
595495008914	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
595495008915	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
595495008916	active site
595495008917	catalytic residue [active]
595495008918	dimer interface [polypeptide binding]; other site
595495008919	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
595495008920	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
595495008921	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
595495008922	shikimate binding site; other site
595495008923	NAD(P) binding site [chemical binding]; other site
595495008924	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495008925	putative substrate translocation pore; other site
595495008926	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495008927	Major Facilitator Superfamily; Region: MFS_1; pfam07690
595495008928	putative substrate translocation pore; other site
595495008929	Domain of unknown function (DUF1870); Region: DUF1870; pfam08965
595495008930	putative inner membrane protein; Provisional; Region: PRK10983
595495008931	Domain of unknown function DUF20; Region: UPF0118; pfam01594
595495008932	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
595495008933	FAD binding domain; Region: FAD_binding_4; pfam01565
595495008934	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
595495008935	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
595495008936	CoenzymeA binding site [chemical binding]; other site
595495008937	subunit interaction site [polypeptide binding]; other site
595495008938	PHB binding site; other site
595495008939	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
595495008940	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
595495008941	putative ABC transporter; Region: ycf24; CHL00085
595495008942	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
595495008943	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
595495008944	Walker A/P-loop; other site
595495008945	ATP binding site [chemical binding]; other site
595495008946	Q-loop/lid; other site
595495008947	ABC transporter signature motif; other site
595495008948	Walker B; other site
595495008949	D-loop; other site
595495008950	H-loop/switch region; other site
595495008951	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
595495008952	FeS assembly protein SufD; Region: sufD; TIGR01981
595495008953	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
595495008954	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
595495008955	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
595495008956	catalytic residue [active]
595495008957	cysteine desufuration protein SufE; Provisional; Region: PRK09296
595495008958	L,D-transpeptidase; Provisional; Region: PRK10190
595495008959	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
595495008960	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
595495008961	murein lipoprotein; Provisional; Region: PRK15396
595495008962	pyruvate kinase; Provisional; Region: PRK09206
595495008963	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
595495008964	domain interfaces; other site
595495008965	active site
595495008966	hypothetical protein; Provisional; Region: PRK10292
595495008967	hypothetical protein; Provisional; Region: PRK09898
595495008968	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
595495008969	putative oxidoreductase; Provisional; Region: PRK09849
595495008970	Aldehyde ferredoxin oxidoreductase, N-terminal domain; Region: AFOR_N; pfam02730
595495008971	Aldehyde ferredoxin oxidoreductase, domains 2 & 3; Region: AFOR_C; pfam01314
595495008972	hypothetical protein; Provisional; Region: PRK09947
595495008973	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
595495008974	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
595495008975	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
595495008976	hypothetical protein; Provisional; Region: PRK09946
595495008977	hypothetical protein; Provisional; Region: PRK09897
595495008978	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
595495008979	putative monooxygenase; Provisional; Region: PRK11118
595495008980	hypothetical protein; Provisional; Region: PRK09945
595495008981	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
595495008982	multidrug efflux protein; Reviewed; Region: PRK01766
595495008983	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
595495008984	cation binding site [ion binding]; other site
595495008985	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
595495008986	Lumazine binding domain; Region: Lum_binding; pfam00677
595495008987	Lumazine binding domain; Region: Lum_binding; pfam00677
595495008988	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
595495008989	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
595495008990	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495008991	S-adenosylmethionine binding site [chemical binding]; other site
595495008992	putative transporter; Provisional; Region: PRK11043
595495008993	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495008994	putative substrate translocation pore; other site
595495008995	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
595495008996	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495008997	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
595495008998	dimerization interface [polypeptide binding]; other site
595495008999	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
595495009000	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
595495009001	DNA binding site [nucleotide binding]
595495009002	domain linker motif; other site
595495009003	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
595495009004	dimerization interface [polypeptide binding]; other site
595495009005	ligand binding site [chemical binding]; other site
595495009006	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495009007	Major Facilitator Superfamily; Region: MFS_1; pfam07690
595495009008	putative substrate translocation pore; other site
595495009009	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
595495009010	Transposase; Region: DEDD_Tnp_IS110; pfam01548
595495009011	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
595495009012	superoxide dismutase; Provisional; Region: PRK10543
595495009013	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
595495009014	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
595495009015	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
595495009016	NlpC/P60 family; Region: NLPC_P60; pfam00877
595495009017	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
595495009018	putative GSH binding site [chemical binding]; other site
595495009019	catalytic residues [active]
595495009020	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
595495009021	putative ATP-dependent helicase Lhr; Provisional; Region: PRK09751
595495009022	ATP binding site [chemical binding]; other site
595495009023	putative Mg++ binding site [ion binding]; other site
595495009024	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
595495009025	nucleotide binding region [chemical binding]; other site
595495009026	ATP-binding site [chemical binding]; other site
595495009027	DEAD/H associated; Region: DEAD_assoc; pfam08494
595495009028	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
595495009029	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
595495009030	dimer interface [polypeptide binding]; other site
595495009031	catalytic site [active]
595495009032	putative active site [active]
595495009033	putative substrate binding site [chemical binding]; other site
595495009034	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
595495009035	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
595495009036	dimer interface [polypeptide binding]; other site
595495009037	active site
595495009038	metal binding site [ion binding]; metal-binding site
595495009039	glutathione binding site [chemical binding]; other site
595495009040	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
595495009041	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
595495009042	FMN binding site [chemical binding]; other site
595495009043	active site
595495009044	substrate binding site [chemical binding]; other site
595495009045	catalytic residue [active]
595495009046	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
595495009047	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
595495009048	Predicted Fe-S protein [General function prediction only]; Region: COG3313
595495009049	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
595495009050	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
595495009051	active site
595495009052	catalytic tetrad [active]
595495009053	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
595495009054	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
595495009055	E-class dimer interface [polypeptide binding]; other site
595495009056	P-class dimer interface [polypeptide binding]; other site
595495009057	active site
595495009058	Cu2+ binding site [ion binding]; other site
595495009059	Zn2+ binding site [ion binding]; other site
595495009060	Fusaric acid resistance protein family; Region: FUSC; pfam04632
595495009061	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
595495009062	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
595495009063	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
595495009064	HlyD family secretion protein; Region: HlyD_3; pfam13437
595495009065	Protein of unknown function (DUF1656); Region: DUF1656; cl11658
595495009066	transcriptional regulator SlyA; Provisional; Region: PRK03573
595495009067	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
595495009068	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
595495009069	Uncharacterized protein family (UPF0075); Region: UPF0075; pfam03702
595495009070	lysozyme inhibitor; Provisional; Region: PRK11372
595495009071	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
595495009072	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
595495009073	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
595495009074	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
595495009075	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
595495009076	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
595495009077	active site
595495009078	HIGH motif; other site
595495009079	dimer interface [polypeptide binding]; other site
595495009080	KMSKS motif; other site
595495009081	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
595495009082	RNA binding surface [nucleotide binding]; other site
595495009083	pyridoxamine kinase; Validated; Region: PRK05756
595495009084	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
595495009085	dimer interface [polypeptide binding]; other site
595495009086	pyridoxal binding site [chemical binding]; other site
595495009087	ATP binding site [chemical binding]; other site
595495009088	glutathionine S-transferase; Provisional; Region: PRK10542
595495009089	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
595495009090	C-terminal domain interface [polypeptide binding]; other site
595495009091	GSH binding site (G-site) [chemical binding]; other site
595495009092	dimer interface [polypeptide binding]; other site
595495009093	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
595495009094	N-terminal domain interface [polypeptide binding]; other site
595495009095	dimer interface [polypeptide binding]; other site
595495009096	substrate binding pocket (H-site) [chemical binding]; other site
595495009097	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
595495009098	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495009099	putative substrate translocation pore; other site
595495009100	POT family; Region: PTR2; pfam00854
595495009101	endonuclease III; Provisional; Region: PRK10702
595495009102	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
595495009103	minor groove reading motif; other site
595495009104	helix-hairpin-helix signature motif; other site
595495009105	substrate binding pocket [chemical binding]; other site
595495009106	active site
595495009107	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
595495009108	electron transport complex RsxE subunit; Provisional; Region: PRK12405
595495009109	electron transport complex protein RnfG; Validated; Region: PRK01908
595495009110	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
595495009111	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
595495009112	SLBB domain; Region: SLBB; pfam10531
595495009113	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
595495009114	electron transport complex protein RnfB; Provisional; Region: PRK05113
595495009115	Putative Fe-S cluster; Region: FeS; pfam04060
595495009116	4Fe-4S binding domain; Region: Fer4; pfam00037
595495009117	electron transport complex protein RsxA; Provisional; Region: PRK05151
595495009118	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
595495009119	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
595495009120	putative oxidoreductase; Provisional; Region: PRK11579
595495009121	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
595495009122	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
595495009123	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
595495009124	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
595495009125	active site
595495009126	purine riboside binding site [chemical binding]; other site
595495009127	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
595495009128	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
595495009129	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495009130	homodimer interface [polypeptide binding]; other site
595495009131	catalytic residue [active]
595495009132	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
595495009133	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
595495009134	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
595495009135	active site turn [active]
595495009136	phosphorylation site [posttranslational modification]
595495009137	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
595495009138	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
595495009139	DNA binding site [nucleotide binding]
595495009140	domain linker motif; other site
595495009141	Ligand-binding domain of MalI, a transcription regulator of the maltose system of Escherichia coli and its close homologs from other bacteria; Region: PBP1_MalI_like; cd06289
595495009142	putative dimerization interface [polypeptide binding]; other site
595495009143	putative ligand binding site [chemical binding]; other site
595495009144	7-alpha-hydroxysteroid dehydrogenase; Validated; Region: PRK06113
595495009145	7 alpha-hydroxysteroid dehydrogenase (7 alpha-HSDH), classical (c) SDRs; Region: 7_alpha_HSDH_SDR_c; cd05365
595495009146	NAD binding site [chemical binding]; other site
595495009147	substrate binding site [chemical binding]; other site
595495009148	homotetramer interface [polypeptide binding]; other site
595495009149	homodimer interface [polypeptide binding]; other site
595495009150	active site
595495009151	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
595495009152	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
595495009153	beta-D-glucuronidase; Provisional; Region: PRK10150
595495009154	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
595495009155	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
595495009156	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
595495009157	glucuronide transporter; Provisional; Region: PRK09848
595495009158	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
595495009159	putative outer membrane porin protein; Provisional; Region: PRK11379
595495009160	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
595495009161	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
595495009162	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
595495009163	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
595495009164	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
595495009165	fumarate hydratase; Provisional; Region: PRK15389
595495009166	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
595495009167	Fumarase C-terminus; Region: Fumerase_C; pfam05683
595495009168	fumarate hydratase; Reviewed; Region: fumC; PRK00485
595495009169	Class II fumarases; Region: Fumarase_classII; cd01362
595495009170	active site
595495009171	tetramer interface [polypeptide binding]; other site
595495009172	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
595495009173	sensor protein RstB; Provisional; Region: PRK10604
595495009174	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
595495009175	dimerization interface [polypeptide binding]; other site
595495009176	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
595495009177	dimer interface [polypeptide binding]; other site
595495009178	phosphorylation site [posttranslational modification]
595495009179	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495009180	ATP binding site [chemical binding]; other site
595495009181	Mg2+ binding site [ion binding]; other site
595495009182	G-X-G motif; other site
595495009183	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
595495009184	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495009185	active site
595495009186	phosphorylation site [posttranslational modification]
595495009187	intermolecular recognition site; other site
595495009188	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
595495009189	DNA binding site [nucleotide binding]
595495009190	GlpM protein; Region: GlpM; pfam06942
595495009191	dihydromonapterin reductase; Provisional; Region: PRK06483
595495009192	pteridine reductase (PR), classical (c) SDRs; Region: PR_SDR_c; cd05357
595495009193	NADP binding site [chemical binding]; other site
595495009194	substrate binding pocket [chemical binding]; other site
595495009195	active site
595495009196	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
595495009197	Spore germination protein; Region: Spore_permease; cl17796
595495009198	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
595495009199	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
595495009200	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
595495009201	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
595495009202	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
595495009203	ligand binding site [chemical binding]; other site
595495009204	homodimer interface [polypeptide binding]; other site
595495009205	NAD(P) binding site [chemical binding]; other site
595495009206	trimer interface B [polypeptide binding]; other site
595495009207	trimer interface A [polypeptide binding]; other site
595495009208	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
595495009209	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
595495009210	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
595495009211	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
595495009212	Domain of unknown function DUF20; Region: UPF0118; pfam01594
595495009213	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
595495009214	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
595495009215	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
595495009216	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
595495009217	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495009218	putative substrate translocation pore; other site
595495009219	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
595495009220	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495009221	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
595495009222	dimerization interface [polypeptide binding]; other site
595495009223	substrate binding pocket [chemical binding]; other site
595495009224	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
595495009225	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
595495009226	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
595495009227	nucleotide binding site [chemical binding]; other site
595495009228	putative dithiobiotin synthetase; Provisional; Region: PRK12374
595495009229	AAA domain; Region: AAA_26; pfam13500
595495009230	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
595495009231	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
595495009232	Cl- selectivity filter; other site
595495009233	Cl- binding residues [ion binding]; other site
595495009234	pore gating glutamate residue; other site
595495009235	dimer interface [polypeptide binding]; other site
595495009236	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
595495009237	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
595495009238	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
595495009239	4Fe-4S binding domain; Region: Fer4; cl02805
595495009240	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
595495009241	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
595495009242	putative [Fe4-S4] binding site [ion binding]; other site
595495009243	putative molybdopterin cofactor binding site [chemical binding]; other site
595495009244	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
595495009245	putative molybdopterin cofactor binding site; other site
595495009246	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
595495009247	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
595495009248	putative [Fe4-S4] binding site [ion binding]; other site
595495009249	putative molybdopterin cofactor binding site [chemical binding]; other site
595495009250	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
595495009251	putative molybdopterin cofactor binding site; other site
595495009252	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
595495009253	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
595495009254	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
595495009255	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
595495009256	Coenzyme A binding pocket [chemical binding]; other site
595495009257	hypothetical protein; Provisional; Region: PRK13659
595495009258	hypothetical protein; Provisional; Region: PRK02237
595495009259	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
595495009260	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
595495009261	putative active site pocket [active]
595495009262	putative metal binding site [ion binding]; other site
595495009263	putative oxidoreductase; Provisional; Region: PRK10083
595495009264	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
595495009265	putative NAD(P) binding site [chemical binding]; other site
595495009266	catalytic Zn binding site [ion binding]; other site
595495009267	structural Zn binding site [ion binding]; other site
595495009268	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495009269	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
595495009270	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
595495009271	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
595495009272	Int/Topo IB signature motif; other site
595495009273	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
595495009274	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
595495009275	active site
595495009276	catalytic site [active]
595495009277	substrate binding site [chemical binding]; other site
595495009278	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
595495009279	DicB protein; Region: DicB; pfam05358
595495009280	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
595495009281	transcriptional repressor DicA; Reviewed; Region: PRK09706
595495009282	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
595495009283	non-specific DNA binding site [nucleotide binding]; other site
595495009284	salt bridge; other site
595495009285	sequence-specific DNA binding site [nucleotide binding]; other site
595495009286	DNA-binding transcriptional regulator DicC; Provisional; Region: PRK09744
595495009287	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
595495009288	primosomal protein DnaI; Provisional; Region: PRK02854
595495009289	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
595495009290	Methyltransferase domain; Region: Methyltransf_25; pfam13649
595495009291	Homeodomain-like domain; Region: HTH_23; pfam13384
595495009292	Winged helix-turn helix; Region: HTH_29; pfam13551
595495009293	Homeodomain-like domain; Region: HTH_32; pfam13565
595495009294	Integrase core domain; Region: rve; pfam00665
595495009295	Integrase core domain; Region: rve_3; cl15866
595495009296	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
595495009297	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
595495009298	Hok/gef family; Region: HOK_GEF; pfam01848
595495009299	Protein of unknown function (DUF968); Region: DUF968; pfam06147
595495009300	Antitermination protein; Region: Antiterm; pfam03589
595495009301	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
595495009302	DnaJ central domain; Region: DnaJ_CXXCXGXG; pfam00684
595495009303	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
595495009304	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
595495009305	DNA-binding site [nucleotide binding]; DNA binding site
595495009306	RNA-binding motif; other site
595495009307	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
595495009308	DNA-binding site [nucleotide binding]; DNA binding site
595495009309	RNA-binding motif; other site
595495009310	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495009311	Lysis protein S; Region: Lysis_S; pfam04971
595495009312	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
595495009313	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
595495009314	catalytic residues [active]
595495009315	Protein of unknown function (DUF2514); Region: DUF2514; pfam10721
595495009316	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
595495009317	DNA-binding site [nucleotide binding]; DNA binding site
595495009318	RNA-binding motif; other site
595495009319	GnsA/GnsB family; Region: GnsAB; pfam08178
595495009320	Protein of unknown function (DUF1398); Region: DUF1398; pfam07166
595495009321	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
595495009322	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
595495009323	gpW; Region: gpW; pfam02831
595495009324	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
595495009325	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
595495009326	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
595495009327	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
595495009328	tandem repeat interface [polypeptide binding]; other site
595495009329	oligomer interface [polypeptide binding]; other site
595495009330	active site residues [active]
595495009331	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
595495009332	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
595495009333	DNA packaging protein FI; Region: Packaging_FI; pfam14000
595495009334	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
595495009335	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
595495009336	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
595495009337	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
595495009338	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
595495009339	phage minor tail protein G; Region: phage_lambda_G; TIGR01674
595495009340	Minor tail protein T; Region: Phage_tail_T; pfam06223
595495009341	Phage-related minor tail protein [Function unknown]; Region: COG5281
595495009342	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
595495009343	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
595495009344	Phage-related protein [Function unknown]; Region: COG4718
595495009345	Phage-related protein [Function unknown]; Region: gp18; COG4672
595495009346	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
595495009347	MPN+ (JAMM) motif; other site
595495009348	Zinc-binding site [ion binding]; other site
595495009349	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
595495009350	NlpC/P60 family; Region: NLPC_P60; cl17555
595495009351	Phage-related protein, tail component [Function unknown]; Region: COG4723
595495009352	Phage-related protein, tail component [Function unknown]; Region: COG4733
595495009353	Putative phage tail protein; Region: Phage-tail_3; pfam13550
595495009354	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
595495009355	Interdomain contacts; other site
595495009356	Cytokine receptor motif; other site
595495009357	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
595495009358	Fibronectin type III protein; Region: DUF3672; pfam12421
595495009359	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
595495009360	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
595495009361	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
595495009362	Phage Tail Collar Domain; Region: Collar; pfam07484
595495009363	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
595495009364	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
595495009365	Resolvase, N terminal domain; Region: Resolvase; pfam00239
595495009366	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
595495009367	DNA-binding interface [nucleotide binding]; DNA binding site
595495009368	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495009369	DNA-binding transcriptional activator FeaR; Provisional; Region: PRK09685
595495009370	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495009371	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
595495009372	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
595495009373	NAD(P) binding site [chemical binding]; other site
595495009374	catalytic residues [active]
595495009375	tyramine oxidase; Provisional; Region: tynA; PRK14696
595495009376	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
595495009377	Copper amine oxidase, N2 domain; Region: Cu_amine_oxidN2; pfam02727
595495009378	Copper amine oxidase, N3 domain; Region: Cu_amine_oxidN3; pfam02728
595495009379	Copper amine oxidase, enzyme domain; Region: Cu_amine_oxid; pfam01179
595495009380	bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; Provisional; Region: PRK11563
595495009381	N-terminal domain of the monoamine oxidase C dehydratase; Region: ALDH_MaoC-N; cd07128
595495009382	substrate binding site [chemical binding]; other site
595495009383	dimer interface [polypeptide binding]; other site
595495009384	NADP binding site [chemical binding]; other site
595495009385	catalytic residues [active]
595495009386	MaoC_C  The C-terminal hot dog fold of the MaoC (monoamine oxidase C) dehydratase regulatory protein. Orthologs of MaoC include PaaZ [Escherichia coli] and PaaN [Pseudomonas putida], which are putative ring-opening enzymes involved in phenylacetic acid...; Region: MaoC_C; cd03452
595495009387	substrate binding site [chemical binding]; other site
595495009388	phenylacetate-CoA oxygenase subunit PaaA; Provisional; Region: paaA; PRK13778
595495009389	phenylacetate-CoA oxygenase, PaaG subunit; Region: PA_CoA_Oxy1; TIGR02156
595495009390	phenylacetate-CoA oxygenase subunit PaaB; Provisional; Region: paaB; PRK13781
595495009391	phenylacetate-CoA oxygenase, PaaI subunit; Region: PA_CoA_Oxy3; TIGR02158
595495009392	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
595495009393	phenylacetate-CoA oxygenase, PaaJ subunit; Region: PA_CoA_Oxy4; TIGR02159
595495009394	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
595495009395	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
595495009396	FAD binding pocket [chemical binding]; other site
595495009397	FAD binding motif [chemical binding]; other site
595495009398	phosphate binding motif [ion binding]; other site
595495009399	beta-alpha-beta structure motif; other site
595495009400	NAD(p) ribose binding residues [chemical binding]; other site
595495009401	NAD binding pocket [chemical binding]; other site
595495009402	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
595495009403	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
595495009404	catalytic loop [active]
595495009405	iron binding site [ion binding]; other site
595495009406	enoyl-CoA hydratase-isomerase; Provisional; Region: PRK09674
595495009407	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
595495009408	substrate binding site [chemical binding]; other site
595495009409	oxyanion hole (OAH) forming residues; other site
595495009410	trimer interface [polypeptide binding]; other site
595495009411	enoyl-CoA hydratase; Provisional; Region: PRK08140
595495009412	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
595495009413	substrate binding site [chemical binding]; other site
595495009414	oxyanion hole (OAH) forming residues; other site
595495009415	trimer interface [polypeptide binding]; other site
595495009416	3-hydroxyacyl-CoA dehydrogenase PaaC; Region: PaaC-3OHAcCoADH; TIGR02279
595495009417	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
595495009418	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
595495009419	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
595495009420	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
595495009421	CoenzymeA binding site [chemical binding]; other site
595495009422	subunit interaction site [polypeptide binding]; other site
595495009423	PHB binding site; other site
595495009424	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
595495009425	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
595495009426	dimer interface [polypeptide binding]; other site
595495009427	active site
595495009428	Phenylacetate-CoA ligase (also known as PaaK); Region: PaaK; cd05913
595495009429	phenylacetate-CoA ligase; Region: PA_CoA_ligase; TIGR02155
595495009430	active site
595495009431	AMP binding site [chemical binding]; other site
595495009432	homodimer interface [polypeptide binding]; other site
595495009433	acyl-activating enzyme (AAE) consensus motif; other site
595495009434	CoA binding site [chemical binding]; other site
595495009435	PaaX-like protein; Region: PaaX; pfam07848
595495009436	phenylacetic acid degradation operon negative regulatory protein PaaX; Region: PaaX_trns_reg; TIGR02277
595495009437	PaaX-like protein C-terminal domain; Region: PaaX_C; pfam08223
595495009438	phenylacetic acid degradation protein PaaY; Region: PaaY; TIGR02287
595495009439	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
595495009440	putative trimer interface [polypeptide binding]; other site
595495009441	putative metal binding site [ion binding]; other site
595495009442	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
595495009443	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
595495009444	active site
595495009445	catalytic tetrad [active]
595495009446	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
595495009447	Protein of unknown function (DUF2773); Region: DUF2773; pfam10971
595495009448	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
595495009449	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase [General function prediction only]; Region: COG4589
595495009450	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
595495009451	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
595495009452	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
595495009453	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495009454	S-adenosylmethionine binding site [chemical binding]; other site
595495009455	PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin; Region: PAP2_Aur1_like; cd03386
595495009456	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
595495009457	active site
595495009458	Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; Region: DSPc; cd00127
595495009459	active site
595495009460	catalytic residues [active]
595495009461	azoreductase; Reviewed; Region: PRK00170
595495009462	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
595495009463	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
595495009464	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
595495009465	ATP binding site [chemical binding]; other site
595495009466	putative Mg++ binding site [ion binding]; other site
595495009467	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
595495009468	nucleotide binding region [chemical binding]; other site
595495009469	ATP-binding site [chemical binding]; other site
595495009470	Helicase associated domain (HA2); Region: HA2; pfam04408
595495009471	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
595495009472	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
595495009473	Uncharacterized conserved protein [Function unknown]; Region: COG1434
595495009474	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
595495009475	putative active site [active]
595495009476	Escherichia coli lactaldehyde dehydrogenase AldA-like; Region: ALDH_LactADH-AldA; cd07088
595495009477	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
595495009478	NAD binding site [chemical binding]; other site
595495009479	catalytic residues [active]
595495009480	substrate binding site [chemical binding]; other site
595495009481	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
595495009482	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
595495009483	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
595495009484	cytochrome b561; Provisional; Region: PRK11513
595495009485	hypothetical protein; Provisional; Region: PRK10040
595495009486	small toxic polypeptide; Provisional; Region: PRK09738
595495009487	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
595495009488	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
595495009489	dimer interface [polypeptide binding]; other site
595495009490	ligand binding site [chemical binding]; other site
595495009491	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
595495009492	dimerization interface [polypeptide binding]; other site
595495009493	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
595495009494	dimer interface [polypeptide binding]; other site
595495009495	putative CheW interface [polypeptide binding]; other site
595495009496	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
595495009497	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495009498	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
595495009499	dimerization interface [polypeptide binding]; other site
595495009500	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
595495009501	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
595495009502	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
595495009503	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
595495009504	hypothetical protein; Provisional; Region: PRK11415
595495009505	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
595495009506	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
595495009507	Coenzyme A binding pocket [chemical binding]; other site
595495009508	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
595495009509	putative trimer interface [polypeptide binding]; other site
595495009510	putative CoA binding site [chemical binding]; other site
595495009511	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
595495009512	putative trimer interface [polypeptide binding]; other site
595495009513	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
595495009514	putative CoA binding site [chemical binding]; other site
595495009515	putative trimer interface [polypeptide binding]; other site
595495009516	putative CoA binding site [chemical binding]; other site
595495009517	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
595495009518	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
595495009519	gating phenylalanine in ion channel; other site
595495009520	tellurite resistance protein TehB; Provisional; Region: PRK11207
595495009521	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495009522	S-adenosylmethionine binding site [chemical binding]; other site
595495009523	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
595495009524	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
595495009525	Probable transposase; Region: OrfB_IS605; pfam01385
595495009526	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
595495009527	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
595495009528	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
595495009529	benzoate transporter; Region: benE; TIGR00843
595495009530	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
595495009531	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
595495009532	non-specific DNA binding site [nucleotide binding]; other site
595495009533	salt bridge; other site
595495009534	sequence-specific DNA binding site [nucleotide binding]; other site
595495009535	Cupin domain; Region: Cupin_2; pfam07883
595495009536	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
595495009537	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
595495009538	Peptidase family U32; Region: Peptidase_U32; pfam01136
595495009539	Collagenase; Region: DUF3656; pfam12392
595495009540	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
595495009541	YcfA-like protein; Region: YcfA; pfam07927
595495009542	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: COG1598
595495009543	Helix-turn-helix; Region: HTH_3; pfam01381
595495009544	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
595495009545	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
595495009546	DNA-binding site [nucleotide binding]; DNA binding site
595495009547	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
595495009548	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495009549	homodimer interface [polypeptide binding]; other site
595495009550	catalytic residue [active]
595495009551	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
595495009552	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
595495009553	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
595495009554	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495009555	Walker A/P-loop; other site
595495009556	ATP binding site [chemical binding]; other site
595495009557	Q-loop/lid; other site
595495009558	ABC transporter signature motif; other site
595495009559	Walker B; other site
595495009560	D-loop; other site
595495009561	H-loop/switch region; other site
595495009562	TOBE domain; Region: TOBE_2; pfam08402
595495009563	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495009564	dimer interface [polypeptide binding]; other site
595495009565	conserved gate region; other site
595495009566	putative PBP binding loops; other site
595495009567	ABC-ATPase subunit interface; other site
595495009568	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
595495009569	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495009570	ABC-ATPase subunit interface; other site
595495009571	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
595495009572	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
595495009573	tetrameric interface [polypeptide binding]; other site
595495009574	NAD binding site [chemical binding]; other site
595495009575	catalytic residues [active]
595495009576	substrate binding site [chemical binding]; other site
595495009577	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
595495009578	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
595495009579	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
595495009580	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
595495009581	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
595495009582	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
595495009583	Prostaglandin dehydrogenases; Region: PGDH; cd05288
595495009584	NAD(P) binding site [chemical binding]; other site
595495009585	substrate binding site [chemical binding]; other site
595495009586	dimer interface [polypeptide binding]; other site
595495009587	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
595495009588	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495009589	6-phospho-beta-glucosidase; Reviewed; Region: celA; PRK09589
595495009590	beta-galactosidase; Region: BGL; TIGR03356
595495009591	hypothetical protein; Provisional; Region: PRK10106
595495009592	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
595495009593	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495009594	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
595495009595	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
595495009596	inner membrane protein; Provisional; Region: PRK10995
595495009597	putative arabinose transporter; Provisional; Region: PRK03545
595495009598	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495009599	putative substrate translocation pore; other site
595495009600	Transcriptional regulator [Transcription]; Region: LysR; COG0583
595495009601	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495009602	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
595495009603	putative dimerization interface [polypeptide binding]; other site
595495009604	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
595495009605	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
595495009606	NAD(P) binding site [chemical binding]; other site
595495009607	catalytic residues [active]
595495009608	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
595495009609	glutaminase; Provisional; Region: PRK00971
595495009610	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
595495009611	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
595495009612	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
595495009613	metal binding site [ion binding]; metal-binding site
595495009614	active site
595495009615	I-site; other site
595495009616	altronate oxidoreductase; Provisional; Region: PRK03643
595495009617	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
595495009618	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
595495009619	Predicted membrane protein [Function unknown]; Region: COG3781
595495009620	Trans-aconitate methyltransferase [General function prediction only]; Region: Tam; COG4106
595495009621	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495009622	S-adenosylmethionine binding site [chemical binding]; other site
595495009623	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
595495009624	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
595495009625	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
595495009626	putative active site; other site
595495009627	catalytic residue [active]
595495009628	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
595495009629	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
595495009630	ligand binding site [chemical binding]; other site
595495009631	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
595495009632	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
595495009633	TM-ABC transporter signature motif; other site
595495009634	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
595495009635	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
595495009636	TM-ABC transporter signature motif; other site
595495009637	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
595495009638	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
595495009639	Walker A/P-loop; other site
595495009640	ATP binding site [chemical binding]; other site
595495009641	Q-loop/lid; other site
595495009642	ABC transporter signature motif; other site
595495009643	Walker B; other site
595495009644	D-loop; other site
595495009645	H-loop/switch region; other site
595495009646	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
595495009647	transcriptional regulator LsrR; Provisional; Region: PRK15418
595495009648	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
595495009649	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
595495009650	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
595495009651	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
595495009652	putative N- and C-terminal domain interface [polypeptide binding]; other site
595495009653	putative active site [active]
595495009654	putative MgATP binding site [chemical binding]; other site
595495009655	catalytic site [active]
595495009656	metal binding site [ion binding]; metal-binding site
595495009657	putative carbohydrate binding site [chemical binding]; other site
595495009658	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495009659	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
595495009660	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
595495009661	Autotransporter beta-domain; Region: Autotransporter; pfam03797
595495009662	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
595495009663	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
595495009664	non-specific DNA binding site [nucleotide binding]; other site
595495009665	salt bridge; other site
595495009666	sequence-specific DNA binding site [nucleotide binding]; other site
595495009667	HipA N-terminal domain; Region: Couple_hipA; pfam13657
595495009668	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
595495009669	HipA-like N-terminal domain; Region: HipA_N; pfam07805
595495009670	HipA-like C-terminal domain; Region: HipA_C; pfam07804
595495009671	Helix-turn-helix domain; Region: HTH_18; pfam12833
595495009672	Fimbrial protein; Region: Fimbrial; cl01416
595495009673	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
595495009674	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
595495009675	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
595495009676	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
595495009677	PapC N-terminal domain; Region: PapC_N; pfam13954
595495009678	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
595495009679	PapC C-terminal domain; Region: PapC_C; pfam13953
595495009680	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
595495009681	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
595495009682	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
595495009683	mannosyl binding site [chemical binding]; other site
595495009684	Fimbrial protein; Region: Fimbrial; pfam00419
595495009685	putative oxidoreductase; Provisional; Region: PRK09939
595495009686	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
595495009687	putative molybdopterin cofactor binding site [chemical binding]; other site
595495009688	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
595495009689	putative molybdopterin cofactor binding site; other site
595495009690	transcriptional regulator YdeO; Provisional; Region: PRK09940
595495009691	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495009692	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
595495009693	Sulfatase; Region: Sulfatase; cl17466
595495009694	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495009695	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
595495009696	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
595495009697	hypothetical protein; Provisional; Region: PRK10695
595495009698	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
595495009699	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
595495009700	putative ligand binding site [chemical binding]; other site
595495009701	putative NAD binding site [chemical binding]; other site
595495009702	catalytic site [active]
595495009703	heat-inducible protein; Provisional; Region: PRK10449
595495009704	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
595495009705	Domain of unknown function (DUF333); Region: DUF333; pfam03891
595495009706	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
595495009707	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
595495009708	dimer interface [polypeptide binding]; other site
595495009709	PYR/PP interface [polypeptide binding]; other site
595495009710	TPP binding site [chemical binding]; other site
595495009711	substrate binding site [chemical binding]; other site
595495009712	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
595495009713	Domain of unknown function; Region: EKR; smart00890
595495009714	4Fe-4S binding domain; Region: Fer4_6; pfam12837
595495009715	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
595495009716	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
595495009717	TPP-binding site [chemical binding]; other site
595495009718	dimer interface [polypeptide binding]; other site
595495009719	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
595495009720	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
595495009721	trimer interface [polypeptide binding]; other site
595495009722	eyelet of channel; other site
595495009723	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
595495009724	Ligand Binding Site [chemical binding]; other site
595495009725	Domain of unknown function (DUF4376); Region: DUF4376; pfam14301
595495009726	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
595495009727	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
595495009728	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
595495009729	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
595495009730	AntA/AntB antirepressor; Region: AntA; cl01430
595495009731	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
595495009732	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
595495009733	N-acetyl-D-glucosamine binding site [chemical binding]; other site
595495009734	catalytic residue [active]
595495009735	Protein of unknown function (DUF3383); Region: DUF3383; pfam11863
595495009736	Uncharacterized protein conserved in bacteria (DUF2213); Region: DUF2213; pfam09979
595495009737	phage-related protein, HI1409 family; Region: phge_rel_HI1409; TIGR01555
595495009738	Terminase small subunit; Region: Terminase_2; cl01513
595495009739	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
595495009740	ParB-like nuclease domain; Region: ParBc; pfam02195
595495009741	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
595495009742	Protein of unknown function (DUF754); Region: DUF754; pfam05449
595495009743	Protein of unknown function (DUF1133); Region: DUF1133; pfam06576
595495009744	Protein of unknown function (DUF1364); Region: DUF1364; pfam07102
595495009745	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
595495009746	Hok/gef family; Region: HOK_GEF; pfam01848
595495009747	Uncharacterized conserved protein [Function unknown]; Region: COG4938
595495009748	Protein of unknown function (DUF3696); Region: DUF3696; pfam12476
595495009749	Protein of unknown function DUF262; Region: DUF262; pfam03235
595495009750	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
595495009751	Protein of unknown function (DUF1627); Region: DUF1627; pfam07789
595495009752	putative replication protein; Provisional; Region: PRK12377
595495009753	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495009754	Walker A motif; other site
595495009755	ATP binding site [chemical binding]; other site
595495009756	Walker B motif; other site
595495009757	arginine finger; other site
595495009758	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3756
595495009759	primosomal protein DnaI; Provisional; Region: PRK02854
595495009760	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
595495009761	Helix-turn-helix domain; Region: HTH_17; cl17695
595495009762	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
595495009763	non-specific DNA binding site [nucleotide binding]; other site
595495009764	salt bridge; other site
595495009765	transcriptional repressor DicA; Reviewed; Region: PRK09706
595495009766	sequence-specific DNA binding site [nucleotide binding]; other site
595495009767	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
595495009768	FtsZ inhibitor protein; Reviewed; Region: kil; PRK11354
595495009769	hypothetical protein; Reviewed; Region: PRK09790
595495009770	exonuclease VIII; Reviewed; Region: PRK09709
595495009771	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
595495009772	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
595495009773	recombination and repair protein RecT; Reviewed; Region: recT; PRK09846
595495009774	restriction alleviation and modification protein; Reviewed; Region: lar; PRK09710
595495009775	hypothetical protein; Provisional; Region: PRK09750
595495009776	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
595495009777	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
595495009778	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
595495009779	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
595495009780	Int/Topo IB signature motif; other site
595495009781	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
595495009782	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
595495009783	Ligand Binding Site [chemical binding]; other site
595495009784	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
595495009785	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
595495009786	ATP binding site [chemical binding]; other site
595495009787	Mg++ binding site [ion binding]; other site
595495009788	motif III; other site
595495009789	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
595495009790	nucleotide binding region [chemical binding]; other site
595495009791	ATP-binding site [chemical binding]; other site
595495009792	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
595495009793	putative RNA binding site [nucleotide binding]; other site
595495009794	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
595495009795	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
595495009796	Cl binding site [ion binding]; other site
595495009797	oligomer interface [polypeptide binding]; other site
595495009798	PAS domain S-box; Region: sensory_box; TIGR00229
595495009799	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
595495009800	putative active site [active]
595495009801	heme pocket [chemical binding]; other site
595495009802	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
595495009803	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
595495009804	metal binding site [ion binding]; metal-binding site
595495009805	active site
595495009806	I-site; other site
595495009807	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
595495009808	Smr domain; Region: Smr; pfam01713
595495009809	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791
595495009810	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495009811	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
595495009812	putative substrate binding pocket [chemical binding]; other site
595495009813	putative dimerization interface [polypeptide binding]; other site
595495009814	M20 Peptidases Aminoacyclase-1 indole-3-acetic-L-aspartic acid hydrolase from bacteria and archaea; Region: M20_Acy1_IAAspH_bact; cd05665
595495009815	amidohydrolase; Region: amidohydrolases; TIGR01891
595495009816	putative metal binding site [ion binding]; other site
595495009817	dimer interface [polypeptide binding]; other site
595495009818	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
595495009819	amidohydrolase; Region: amidohydrolases; TIGR01891
595495009820	putative metal binding site [ion binding]; other site
595495009821	putative aminobenzoyl-glutamate transporter; Provisional; Region: abgT; PRK11339
595495009822	p-Aminobenzoyl-glutamate transporter family; Region: ydaH; TIGR00819
595495009823	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
595495009824	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
595495009825	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
595495009826	DNA binding site [nucleotide binding]
595495009827	active site
595495009828	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
595495009829	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
595495009830	ligand binding site [chemical binding]; other site
595495009831	flexible hinge region; other site
595495009832	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
595495009833	putative switch regulator; other site
595495009834	non-specific DNA interactions [nucleotide binding]; other site
595495009835	DNA binding site [nucleotide binding]
595495009836	sequence specific DNA binding site [nucleotide binding]; other site
595495009837	putative cAMP binding site [chemical binding]; other site
595495009838	universal stress protein UspE; Provisional; Region: PRK11175
595495009839	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
595495009840	Ligand Binding Site [chemical binding]; other site
595495009841	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
595495009842	Ligand Binding Site [chemical binding]; other site
595495009843	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
595495009844	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495009845	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
595495009846	Mechanosensitive ion channel; Region: MS_channel; pfam00924
595495009847	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
595495009848	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
595495009849	peptide binding site [polypeptide binding]; other site
595495009850	Uncharacterized BCR, COG1636; Region: DUF208; cl17782
595495009851	Transcriptional regulator [Transcription]; Region: LysR; COG0583
595495009852	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495009853	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
595495009854	putative effector binding pocket; other site
595495009855	putative dimerization interface [polypeptide binding]; other site
595495009856	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
595495009857	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
595495009858	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
595495009859	atypical (a) SDRs, subgroup 6; Region: SDR_a6; cd05267
595495009860	NADH(P)-binding; Region: NAD_binding_10; pfam13460
595495009861	putative NAD(P) binding site [chemical binding]; other site
595495009862	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
595495009863	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
595495009864	putative active site [active]
595495009865	Zn binding site [ion binding]; other site
595495009866	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
595495009867	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
595495009868	active site
595495009869	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
595495009870	dimer interface [polypeptide binding]; other site
595495009871	catalytic triad [active]
595495009872	peroxidatic and resolving cysteines [active]
595495009873	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
595495009874	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
595495009875	putative aromatic amino acid binding site; other site
595495009876	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495009877	Walker A motif; other site
595495009878	ATP binding site [chemical binding]; other site
595495009879	Walker B motif; other site
595495009880	arginine finger; other site
595495009881	Predicted membrane protein [Function unknown]; Region: COG3768
595495009882	TIGR01620 family protein; Region: hyp_HI0043
595495009883	Predicted ATPase [General function prediction only]; Region: COG3106
595495009884	Transcriptional regulators [Transcription]; Region: PurR; COG1609
595495009885	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
595495009886	DNA binding site [nucleotide binding]
595495009887	domain linker motif; other site
595495009888	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
595495009889	putative dimerization interface [polypeptide binding]; other site
595495009890	putative ligand binding site [chemical binding]; other site
595495009891	Outer membrane protein G (OmpG); Region: Porin_OmpG; pfam09381
595495009892	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
595495009893	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
595495009894	Walker A/P-loop; other site
595495009895	ATP binding site [chemical binding]; other site
595495009896	Q-loop/lid; other site
595495009897	ABC transporter signature motif; other site
595495009898	Walker B; other site
595495009899	D-loop; other site
595495009900	H-loop/switch region; other site
595495009901	TOBE domain; Region: TOBE_2; pfam08402
595495009902	beta-phosphoglucomutase; Region: bPGM; TIGR01990
595495009903	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495009904	motif II; other site
595495009905	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
595495009906	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
595495009907	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
595495009908	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
595495009909	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
595495009910	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
595495009911	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
595495009912	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
595495009913	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
595495009914	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide and other MDR family members; Region: 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_; cd08255
595495009915	putative NAD(P) binding site [chemical binding]; other site
595495009916	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
595495009917	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495009918	dimer interface [polypeptide binding]; other site
595495009919	conserved gate region; other site
595495009920	putative PBP binding loops; other site
595495009921	ABC-ATPase subunit interface; other site
595495009922	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495009923	dimer interface [polypeptide binding]; other site
595495009924	conserved gate region; other site
595495009925	putative PBP binding loops; other site
595495009926	ABC-ATPase subunit interface; other site
595495009927	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
595495009928	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
595495009929	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
595495009930	sucrose phosphorylase; Provisional; Region: PRK13840
595495009931	active site
595495009932	homodimer interface [polypeptide binding]; other site
595495009933	catalytic site [active]
595495009934	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
595495009935	active site residue [active]
595495009936	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
595495009937	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
595495009938	phage shock protein C; Region: phageshock_pspC; TIGR02978
595495009939	phage shock protein B; Provisional; Region: pspB; PRK09458
595495009940	phage shock protein PspA; Provisional; Region: PRK10698
595495009941	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
595495009942	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495009943	Walker A motif; other site
595495009944	ATP binding site [chemical binding]; other site
595495009945	Walker B motif; other site
595495009946	arginine finger; other site
595495009947	4-aminobutyrate transaminase; Provisional; Region: PRK09792
595495009948	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
595495009949	inhibitor-cofactor binding pocket; inhibition site
595495009950	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495009951	catalytic residue [active]
595495009952	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
595495009953	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
595495009954	gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK09847
595495009955	Escherichia coli NADP+-dependent gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase PuuC-like; Region: ALDH_GABALDH-PuuC; cd07112
595495009956	NAD(P) binding site [chemical binding]; other site
595495009957	catalytic residues [active]
595495009958	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
595495009959	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
595495009960	non-specific DNA binding site [nucleotide binding]; other site
595495009961	salt bridge; other site
595495009962	sequence-specific DNA binding site [nucleotide binding]; other site
595495009963	Cupin domain; Region: Cupin_2; pfam07883
595495009964	gamma-glutamyl-gamma-aminobutyrate hydrolase; Provisional; Region: puuD; PRK11366
595495009965	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
595495009966	catalytic triad [active]
595495009967	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
595495009968	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
595495009969	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
595495009970	Protein of unknown function (DUF2543); Region: DUF2543; pfam10820
595495009971	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
595495009972	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
595495009973	peptide binding site [polypeptide binding]; other site
595495009974	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
595495009975	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495009976	dimer interface [polypeptide binding]; other site
595495009977	conserved gate region; other site
595495009978	putative PBP binding loops; other site
595495009979	ABC-ATPase subunit interface; other site
595495009980	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
595495009981	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
595495009982	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495009983	dimer interface [polypeptide binding]; other site
595495009984	conserved gate region; other site
595495009985	putative PBP binding loops; other site
595495009986	ABC-ATPase subunit interface; other site
595495009987	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
595495009988	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
595495009989	Walker A/P-loop; other site
595495009990	ATP binding site [chemical binding]; other site
595495009991	Q-loop/lid; other site
595495009992	ABC transporter signature motif; other site
595495009993	Walker B; other site
595495009994	D-loop; other site
595495009995	H-loop/switch region; other site
595495009996	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
595495009997	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
595495009998	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
595495009999	Walker A/P-loop; other site
595495010000	ATP binding site [chemical binding]; other site
595495010001	Q-loop/lid; other site
595495010002	ABC transporter signature motif; other site
595495010003	Walker B; other site
595495010004	D-loop; other site
595495010005	H-loop/switch region; other site
595495010006	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
595495010007	putative active site [active]
595495010008	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
595495010009	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
595495010010	NAD binding site [chemical binding]; other site
595495010011	homotetramer interface [polypeptide binding]; other site
595495010012	homodimer interface [polypeptide binding]; other site
595495010013	substrate binding site [chemical binding]; other site
595495010014	active site
595495010015	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
595495010016	Uncharacterized conserved protein [Function unknown]; Region: COG2128
595495010017	exoribonuclease II; Provisional; Region: PRK05054
595495010018	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
595495010019	RNB domain; Region: RNB; pfam00773
595495010020	S1 RNA binding domain; Region: S1; pfam00575
595495010021	RNase II stability modulator; Provisional; Region: PRK10060
595495010022	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
595495010023	putative active site [active]
595495010024	heme pocket [chemical binding]; other site
595495010025	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
595495010026	metal binding site [ion binding]; metal-binding site
595495010027	active site
595495010028	I-site; other site
595495010029	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
595495010030	hypothetical protein; Provisional; Region: PRK13658
595495010031	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
595495010032	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
595495010033	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
595495010034	lipoprotein; Provisional; Region: PRK10540
595495010035	translation initiation factor Sui1; Validated; Region: PRK06824
595495010036	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
595495010037	putative rRNA binding site [nucleotide binding]; other site
595495010038	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
595495010039	active site
595495010040	dimer interface [polypeptide binding]; other site
595495010041	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
595495010042	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
595495010043	TPR motif; other site
595495010044	binding surface
595495010045	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
595495010046	binding surface
595495010047	TPR motif; other site
595495010048	Predicted membrane protein [Function unknown]; Region: COG3771
595495010049	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
595495010050	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
595495010051	active site
595495010052	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
595495010053	dimerization interface [polypeptide binding]; other site
595495010054	active site
595495010055	aconitate hydratase; Validated; Region: PRK09277
595495010056	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
595495010057	substrate binding site [chemical binding]; other site
595495010058	ligand binding site [chemical binding]; other site
595495010059	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
595495010060	substrate binding site [chemical binding]; other site
595495010061	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
595495010062	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495010063	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
595495010064	substrate binding site [chemical binding]; other site
595495010065	putative dimerization interface [polypeptide binding]; other site
595495010066	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
595495010067	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
595495010068	active site
595495010069	interdomain interaction site; other site
595495010070	putative metal-binding site [ion binding]; other site
595495010071	nucleotide binding site [chemical binding]; other site
595495010072	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
595495010073	domain I; other site
595495010074	DNA binding groove [nucleotide binding]
595495010075	phosphate binding site [ion binding]; other site
595495010076	domain II; other site
595495010077	domain III; other site
595495010078	nucleotide binding site [chemical binding]; other site
595495010079	catalytic site [active]
595495010080	domain IV; other site
595495010081	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
595495010082	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
595495010083	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
595495010084	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
595495010085	hypothetical protein; Provisional; Region: PRK11037
595495010086	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
595495010087	putative inner membrane peptidase; Provisional; Region: PRK11778
595495010088	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
595495010089	tandem repeat interface [polypeptide binding]; other site
595495010090	oligomer interface [polypeptide binding]; other site
595495010091	active site residues [active]
595495010092	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
595495010093	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
595495010094	NADP binding site [chemical binding]; other site
595495010095	homodimer interface [polypeptide binding]; other site
595495010096	active site
595495010097	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
595495010098	Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557
595495010099	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
595495010100	homodimer interface [polypeptide binding]; other site
595495010101	Walker A motif; other site
595495010102	ATP binding site [chemical binding]; other site
595495010103	hydroxycobalamin binding site [chemical binding]; other site
595495010104	Walker B motif; other site
595495010105	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
595495010106	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
595495010107	RNA binding surface [nucleotide binding]; other site
595495010108	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
595495010109	probable active site [active]
595495010110	hypothetical protein; Provisional; Region: PRK11630
595495010111	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
595495010112	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
595495010113	active site
595495010114	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
595495010115	anthranilate synthase component I; Provisional; Region: PRK13564
595495010116	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
595495010117	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
595495010118	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
595495010119	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
595495010120	glutamine binding [chemical binding]; other site
595495010121	catalytic triad [active]
595495010122	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
595495010123	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
595495010124	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
595495010125	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
595495010126	active site
595495010127	ribulose/triose binding site [chemical binding]; other site
595495010128	phosphate binding site [ion binding]; other site
595495010129	substrate (anthranilate) binding pocket [chemical binding]; other site
595495010130	product (indole) binding pocket [chemical binding]; other site
595495010131	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
595495010132	active site
595495010133	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
595495010134	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
595495010135	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495010136	catalytic residue [active]
595495010137	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
595495010138	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
595495010139	substrate binding site [chemical binding]; other site
595495010140	active site
595495010141	catalytic residues [active]
595495010142	heterodimer interface [polypeptide binding]; other site
595495010143	General stress protein [General function prediction only]; Region: GsiB; COG3729
595495010144	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
595495010145	dimerization interface [polypeptide binding]; other site
595495010146	metal binding site [ion binding]; metal-binding site
595495010147	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3685
595495010148	outer membrane protein W; Provisional; Region: PRK10959
595495010149	hypothetical protein; Provisional; Region: PRK02868
595495010150	intracellular septation protein A; Reviewed; Region: PRK00259
595495010151	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
595495010152	transport protein TonB; Provisional; Region: PRK10819
595495010153	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
595495010154	YciI-like protein; Reviewed; Region: PRK11370
595495010155	voltage-gated potassium channel; Provisional; Region: PRK10537
595495010156	Ion channel; Region: Ion_trans_2; pfam07885
595495010157	TrkA-N domain; Region: TrkA_N; pfam02254
595495010158	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
595495010159	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
595495010160	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
595495010161	putative active site [active]
595495010162	catalytic site [active]
595495010163	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
595495010164	putative active site [active]
595495010165	catalytic site [active]
595495010166	dsDNA-mimic protein; Reviewed; Region: PRK05094
595495010167	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
595495010168	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
595495010169	Walker A/P-loop; other site
595495010170	ATP binding site [chemical binding]; other site
595495010171	Q-loop/lid; other site
595495010172	ABC transporter signature motif; other site
595495010173	Walker B; other site
595495010174	D-loop; other site
595495010175	H-loop/switch region; other site
595495010176	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
595495010177	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
595495010178	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
595495010179	Walker A/P-loop; other site
595495010180	ATP binding site [chemical binding]; other site
595495010181	Q-loop/lid; other site
595495010182	ABC transporter signature motif; other site
595495010183	Walker B; other site
595495010184	D-loop; other site
595495010185	H-loop/switch region; other site
595495010186	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
595495010187	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
595495010188	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
595495010189	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495010190	dimer interface [polypeptide binding]; other site
595495010191	conserved gate region; other site
595495010192	putative PBP binding loops; other site
595495010193	ABC-ATPase subunit interface; other site
595495010194	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
595495010195	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495010196	dimer interface [polypeptide binding]; other site
595495010197	conserved gate region; other site
595495010198	putative PBP binding loops; other site
595495010199	ABC-ATPase subunit interface; other site
595495010200	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
595495010201	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
595495010202	peptide binding site [polypeptide binding]; other site
595495010203	hypothetical protein; Provisional; Region: PRK11111
595495010204	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
595495010205	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
595495010206	putative catalytic cysteine [active]
595495010207	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
595495010208	putative active site [active]
595495010209	metal binding site [ion binding]; metal-binding site
595495010210	thymidine kinase; Provisional; Region: PRK04296
595495010211	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
595495010212	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
595495010213	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
595495010214	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
595495010215	active site
595495010216	tetramer interface; other site
595495010217	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495010218	active site
595495010219	response regulator of RpoS; Provisional; Region: PRK10693
595495010220	phosphorylation site [posttranslational modification]
595495010221	intermolecular recognition site; other site
595495010222	dimerization interface [polypeptide binding]; other site
595495010223	hypothetical protein; Provisional; Region: PRK10279
595495010224	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
595495010225	active site
595495010226	nucleophile elbow; other site
595495010227	hypothetical protein; Provisional; Region: PRK01617
595495010228	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
595495010229	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
595495010230	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
595495010231	putative active site [active]
595495010232	putative substrate binding site [chemical binding]; other site
595495010233	putative cosubstrate binding site; other site
595495010234	catalytic site [active]
595495010235	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
595495010236	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
595495010237	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
595495010238	4Fe-4S binding domain; Region: Fer4; cl02805
595495010239	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
595495010240	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
595495010241	[4Fe-4S] binding site [ion binding]; other site
595495010242	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
595495010243	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
595495010244	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
595495010245	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
595495010246	molybdopterin cofactor binding site; other site
595495010247	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
595495010248	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
595495010249	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
595495010250	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
595495010251	dimerization interface [polypeptide binding]; other site
595495010252	Histidine kinase; Region: HisKA_3; pfam07730
595495010253	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495010254	ATP binding site [chemical binding]; other site
595495010255	Mg2+ binding site [ion binding]; other site
595495010256	G-X-G motif; other site
595495010257	transcriptional regulator NarL; Provisional; Region: PRK10651
595495010258	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495010259	active site
595495010260	phosphorylation site [posttranslational modification]
595495010261	intermolecular recognition site; other site
595495010262	dimerization interface [polypeptide binding]; other site
595495010263	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
595495010264	DNA binding residues [nucleotide binding]
595495010265	dimerization interface [polypeptide binding]; other site
595495010266	putative invasin; Provisional; Region: PRK10177
595495010267	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
595495010268	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
595495010269	Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism]; Region: ChaC; COG3703
595495010270	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
595495010271	putative active site pocket [active]
595495010272	dimerization interface [polypeptide binding]; other site
595495010273	putative catalytic residue [active]
595495010274	cation transport regulator; Reviewed; Region: chaB; PRK09582
595495010275	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495010276	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
595495010277	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
595495010278	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
595495010279	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
595495010280	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
595495010281	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
595495010282	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
595495010283	hypothetical protein; Provisional; Region: PRK10941
595495010284	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
595495010285	hypothetical protein; Provisional; Region: PRK10278
595495010286	HemK family putative methylases; Region: hemK_fam; TIGR00536
595495010287	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495010288	peptide chain release factor 1; Validated; Region: prfA; PRK00591
595495010289	This domain is found in peptide chain release factors; Region: PCRF; smart00937
595495010290	RF-1 domain; Region: RF-1; pfam00472
595495010291	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
595495010292	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
595495010293	tRNA; other site
595495010294	putative tRNA binding site [nucleotide binding]; other site
595495010295	putative NADP binding site [chemical binding]; other site
595495010296	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
595495010297	outer membrane lipoprotein LolB; Region: lolB; TIGR00548
595495010298	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
595495010299	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
595495010300	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
595495010301	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
595495010302	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
595495010303	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
595495010304	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
595495010305	active site
595495010306	putative transporter; Provisional; Region: PRK11660
595495010307	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
595495010308	Sulfate transporter family; Region: Sulfate_transp; pfam00916
595495010309	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
595495010310	hypothetical protein; Provisional; Region: PRK10692
595495010311	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
595495010312	putative active site [active]
595495010313	catalytic residue [active]
595495010314	GTP-binding protein YchF; Reviewed; Region: PRK09601
595495010315	YchF GTPase; Region: YchF; cd01900
595495010316	G1 box; other site
595495010317	GTP/Mg2+ binding site [chemical binding]; other site
595495010318	Switch I region; other site
595495010319	G2 box; other site
595495010320	Switch II region; other site
595495010321	G3 box; other site
595495010322	G4 box; other site
595495010323	G5 box; other site
595495010324	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
595495010325	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
595495010326	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
595495010327	Autotransporter beta-domain; Region: Autotransporter; pfam03797
595495010328	DNA-binding transcriptional regulator DhaR; Provisional; Region: PRK11388
595495010329	PAS domain; Region: PAS; smart00091
595495010330	putative active site [active]
595495010331	heme pocket [chemical binding]; other site
595495010332	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495010333	Walker A motif; other site
595495010334	ATP binding site [chemical binding]; other site
595495010335	Walker B motif; other site
595495010336	arginine finger; other site
595495010337	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
595495010338	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK11468
595495010339	Dak1 domain; Region: Dak1; pfam02733
595495010340	dihydroxyacetone kinase subunit DhaL; Provisional; Region: PRK10005
595495010341	dihydroxyacetone kinase subunit M; Provisional; Region: PRK11377
595495010342	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3412
595495010343	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
595495010344	dimerization domain swap beta strand [polypeptide binding]; other site
595495010345	regulatory protein interface [polypeptide binding]; other site
595495010346	active site
595495010347	regulatory phosphorylation site [posttranslational modification]; other site
595495010348	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
595495010349	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
595495010350	trehalase; Provisional; Region: treA; PRK13271
595495010351	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
595495010352	hypothetical protein; Provisional; Region: PRK10457
595495010353	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
595495010354	Flagellar regulator YcgR; Region: YcgR; pfam07317
595495010355	PilZ domain; Region: PilZ; pfam07238
595495010356	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
595495010357	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
595495010358	N-acetyl-D-glucosamine binding site [chemical binding]; other site
595495010359	catalytic residue [active]
595495010360	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
595495010361	dimer interface [polypeptide binding]; other site
595495010362	catalytic triad [active]
595495010363	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
595495010364	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
595495010365	TrkA-C domain; Region: TrkA_C; pfam02080
595495010366	Transporter associated domain; Region: CorC_HlyC; smart01091
595495010367	alanine racemase; Reviewed; Region: dadX; PRK03646
595495010368	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
595495010369	active site
595495010370	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
595495010371	substrate binding site [chemical binding]; other site
595495010372	catalytic residues [active]
595495010373	dimer interface [polypeptide binding]; other site
595495010374	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
595495010375	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
595495010376	SpoVR family protein; Provisional; Region: PRK11767
595495010377	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
595495010378	fatty acid metabolism regulator; Provisional; Region: PRK04984
595495010379	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
595495010380	DNA-binding site [nucleotide binding]; DNA binding site
595495010381	FadR C-terminal domain; Region: FadR_C; pfam07840
595495010382	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
595495010383	transmembrane helices; other site
595495010384	disulfide bond formation protein B; Provisional; Region: PRK01749
595495010385	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
595495010386	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
595495010387	active site
595495010388	DNA binding site [nucleotide binding]
595495010389	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
595495010390	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
595495010391	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
595495010392	Catalytic site [active]
595495010393	Haemolysin E (HlyE); Region: HlyE; cl11627
595495010394	Haemolysin E (HlyE); Region: HlyE; cl11627
595495010395	hypothetical protein; Provisional; Region: PRK05170
595495010396	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
595495010397	hypothetical protein; Provisional; Region: PRK10691
595495010398	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
595495010399	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
595495010400	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
595495010401	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
595495010402	septum formation inhibitor; Reviewed; Region: minC; PRK03511
595495010403	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
595495010404	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
595495010405	cell division inhibitor MinD; Provisional; Region: PRK10818
595495010406	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
595495010407	Switch I; other site
595495010408	Switch II; other site
595495010409	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
595495010410	Autotransporter beta-domain; Region: Autotransporter; cl17461
595495010411	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
595495010412	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
595495010413	Autotransporter beta-domain; Region: Autotransporter; smart00869
595495010414	heme ABC transporter, heme-binding protein isdE; Region: IsdE; TIGR03659
595495010415	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
595495010416	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
595495010417	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
595495010418	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
595495010419	Sensors of blue-light using FAD; Region: BLUF; smart01034
595495010420	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
595495010421	transcriptional regulator MirA; Provisional; Region: PRK15043
595495010422	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
595495010423	DNA binding residues [nucleotide binding]
595495010424	Protein of unknown function (DUF1398); Region: DUF1398; pfam07166
595495010425	anti-adapter protein IraM; Provisional; Region: PRK09919
595495010426	isocitrate dehydrogenase; Validated; Region: PRK07362
595495010427	isocitrate dehydrogenase; Reviewed; Region: PRK07006
595495010428	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
595495010429	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
595495010430	probable active site [active]
595495010431	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
595495010432	nudix motif; other site
595495010433	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
595495010434	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
595495010435	putative lysogenization regulator; Reviewed; Region: PRK00218
595495010436	adenylosuccinate lyase; Provisional; Region: PRK09285
595495010437	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
595495010438	tetramer interface [polypeptide binding]; other site
595495010439	active site
595495010440	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
595495010441	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495010442	active site
595495010443	phosphorylation site [posttranslational modification]
595495010444	intermolecular recognition site; other site
595495010445	dimerization interface [polypeptide binding]; other site
595495010446	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
595495010447	DNA binding site [nucleotide binding]
595495010448	sensor protein PhoQ; Provisional; Region: PRK10815
595495010449	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
595495010450	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
595495010451	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
595495010452	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495010453	ATP binding site [chemical binding]; other site
595495010454	Mg2+ binding site [ion binding]; other site
595495010455	G-X-G motif; other site
595495010456	Uncharacterized conserved protein [Function unknown]; Region: COG2850
595495010457	Cupin-like domain; Region: Cupin_8; pfam13621
595495010458	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
595495010459	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
595495010460	metal binding site [ion binding]; metal-binding site
595495010461	dimer interface [polypeptide binding]; other site
595495010462	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
595495010463	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495010464	Walker A/P-loop; other site
595495010465	ATP binding site [chemical binding]; other site
595495010466	Q-loop/lid; other site
595495010467	ABC transporter signature motif; other site
595495010468	Walker B; other site
595495010469	D-loop; other site
595495010470	H-loop/switch region; other site
595495010471	TOBE domain; Region: TOBE_2; pfam08402
595495010472	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
595495010473	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495010474	dimer interface [polypeptide binding]; other site
595495010475	conserved gate region; other site
595495010476	putative PBP binding loops; other site
595495010477	ABC-ATPase subunit interface; other site
595495010478	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
595495010479	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495010480	dimer interface [polypeptide binding]; other site
595495010481	conserved gate region; other site
595495010482	putative PBP binding loops; other site
595495010483	ABC-ATPase subunit interface; other site
595495010484	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
595495010485	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
595495010486	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
595495010487	Repair protein; Region: Repair_PSII; cl01535
595495010488	NAD-dependent deacetylase; Provisional; Region: PRK00481
595495010489	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
595495010490	NAD+ binding site [chemical binding]; other site
595495010491	substrate binding site [chemical binding]; other site
595495010492	Zn binding site [ion binding]; other site
595495010493	fructokinase; Reviewed; Region: PRK09557
595495010494	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
595495010495	nucleotide binding site [chemical binding]; other site
595495010496	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
595495010497	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
595495010498	FtsX-like permease family; Region: FtsX; pfam02687
595495010499	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
595495010500	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
595495010501	Walker A/P-loop; other site
595495010502	ATP binding site [chemical binding]; other site
595495010503	Q-loop/lid; other site
595495010504	ABC transporter signature motif; other site
595495010505	Walker B; other site
595495010506	D-loop; other site
595495010507	H-loop/switch region; other site
595495010508	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
595495010509	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
595495010510	FtsX-like permease family; Region: FtsX; pfam02687
595495010511	Predicted membrane protein [Function unknown]; Region: COG4763
595495010512	Acyltransferase family; Region: Acyl_transf_3; pfam01757
595495010513	transcription-repair coupling factor; Provisional; Region: PRK10689
595495010514	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
595495010515	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
595495010516	ATP binding site [chemical binding]; other site
595495010517	putative Mg++ binding site [ion binding]; other site
595495010518	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
595495010519	nucleotide binding region [chemical binding]; other site
595495010520	ATP-binding site [chemical binding]; other site
595495010521	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
595495010522	L,D-transpeptidase; Provisional; Region: PRK10260
595495010523	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
595495010524	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
595495010525	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
595495010526	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
595495010527	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
595495010528	hypothetical protein; Provisional; Region: PRK11280
595495010529	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
595495010530	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
595495010531	hypothetical protein; Provisional; Region: PRK04940
595495010532	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
595495010533	beta-hexosaminidase; Provisional; Region: PRK05337
595495010534	thiamine kinase; Region: ycfN_thiK; TIGR02721
595495010535	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
595495010536	active site
595495010537	substrate binding site [chemical binding]; other site
595495010538	ATP binding site [chemical binding]; other site
595495010539	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
595495010540	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
595495010541	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
595495010542	putative dimer interface [polypeptide binding]; other site
595495010543	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
595495010544	nucleotide binding site/active site [active]
595495010545	HIT family signature motif; other site
595495010546	catalytic residue [active]
595495010547	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
595495010548	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
595495010549	N-terminal plug; other site
595495010550	ligand-binding site [chemical binding]; other site
595495010551	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
595495010552	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
595495010553	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
595495010554	active site turn [active]
595495010555	phosphorylation site [posttranslational modification]
595495010556	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
595495010557	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
595495010558	active site
595495010559	DNA polymerase III subunit delta'; Validated; Region: PRK07993
595495010560	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
595495010561	thymidylate kinase; Validated; Region: tmk; PRK00698
595495010562	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
595495010563	TMP-binding site; other site
595495010564	ATP-binding site [chemical binding]; other site
595495010565	conserved hypothetical protein, YceG family; Region: TIGR00247
595495010566	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
595495010567	dimerization interface [polypeptide binding]; other site
595495010568	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
595495010569	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
595495010570	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495010571	catalytic residue [active]
595495010572	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
595495010573	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
595495010574	dimer interface [polypeptide binding]; other site
595495010575	active site
595495010576	acyl carrier protein; Provisional; Region: acpP; PRK00982
595495010577	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
595495010578	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
595495010579	NAD(P) binding site [chemical binding]; other site
595495010580	homotetramer interface [polypeptide binding]; other site
595495010581	homodimer interface [polypeptide binding]; other site
595495010582	active site
595495010583	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
595495010584	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
595495010585	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
595495010586	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
595495010587	dimer interface [polypeptide binding]; other site
595495010588	active site
595495010589	CoA binding pocket [chemical binding]; other site
595495010590	putative phosphate acyltransferase; Provisional; Region: PRK05331
595495010591	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
595495010592	hypothetical protein; Provisional; Region: PRK11193
595495010593	Maf-like protein; Region: Maf; pfam02545
595495010594	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
595495010595	active site
595495010596	dimer interface [polypeptide binding]; other site
595495010597	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
595495010598	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
595495010599	RNA binding surface [nucleotide binding]; other site
595495010600	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
595495010601	active site
595495010602	Protein of unknown function (DUF2655); Region: DUF2655; pfam10848
595495010603	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
595495010604	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
595495010605	homodimer interface [polypeptide binding]; other site
595495010606	oligonucleotide binding site [chemical binding]; other site
595495010607	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
595495010608	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
595495010609	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
595495010610	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
595495010611	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
595495010612	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
595495010613	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
595495010614	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
595495010615	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
595495010616	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
595495010617	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
595495010618	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
595495010619	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
595495010620	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
595495010621	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
595495010622	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
595495010623	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
595495010624	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
595495010625	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
595495010626	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
595495010627	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
595495010628	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
595495010629	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
595495010630	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
595495010631	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
595495010632	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
595495010633	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
595495010634	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
595495010635	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
595495010636	flagellar basal-body rod protein FlgB; Region: FlgB; TIGR01396
595495010637	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
595495010638	Flagellar basal body P-ring biosynthesis protein [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FlgA; COG1261
595495010639	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
595495010640	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
595495010641	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
595495010642	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
595495010643	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
595495010644	MviN-like protein; Region: MVIN; pfam03023
595495010645	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
595495010646	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
595495010647	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
595495010648	hypothetical protein; Provisional; Region: PRK11239
595495010649	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
595495010650	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
595495010651	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
595495010652	multidrug resistance protein MdtH; Provisional; Region: PRK11646
595495010653	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495010654	putative substrate translocation pore; other site
595495010655	glutaredoxin 2; Provisional; Region: PRK10387
595495010656	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
595495010657	C-terminal domain interface [polypeptide binding]; other site
595495010658	GSH binding site (G-site) [chemical binding]; other site
595495010659	catalytic residues [active]
595495010660	putative dimer interface [polypeptide binding]; other site
595495010661	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
595495010662	N-terminal domain interface [polypeptide binding]; other site
595495010663	lipoprotein; Provisional; Region: PRK10598
595495010664	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
595495010665	active site
595495010666	substrate binding pocket [chemical binding]; other site
595495010667	dimer interface [polypeptide binding]; other site
595495010668	DNA damage-inducible protein I; Provisional; Region: PRK10597
595495010669	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
595495010670	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
595495010671	hydroxyglutarate oxidase; Provisional; Region: PRK11728
595495010672	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
595495010673	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
595495010674	hypothetical protein; Provisional; Region: PRK03757
595495010675	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
595495010676	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
595495010677	active site residue [active]
595495010678	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
595495010679	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
595495010680	putative acyl-acceptor binding pocket; other site
595495010681	drug efflux system protein MdtG; Provisional; Region: PRK09874
595495010682	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495010683	putative substrate translocation pore; other site
595495010684	secY/secA suppressor protein; Provisional; Region: PRK11467
595495010685	lipoprotein; Provisional; Region: PRK10175
595495010686	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
595495010687	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
595495010688	Ligand binding site; other site
595495010689	DXD motif; other site
595495010690	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
595495010691	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
595495010692	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
595495010693	Acyltransferase family; Region: Acyl_transf_3; pfam01757
595495010694	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
595495010695	PLD-like domain; Region: PLDc_2; pfam13091
595495010696	putative active site [active]
595495010697	catalytic site [active]
595495010698	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
595495010699	PLD-like domain; Region: PLDc_2; pfam13091
595495010700	putative active site [active]
595495010701	catalytic site [active]
595495010702	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
595495010703	putative ADP-ribose binding site [chemical binding]; other site
595495010704	putative active site [active]
595495010705	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
595495010706	major curlin subunit; Provisional; Region: csgA; PRK10051
595495010707	Curlin associated repeat; Region: Curlin_rpt; pfam07012
595495010708	Curlin associated repeat; Region: Curlin_rpt; pfam07012
595495010709	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
595495010710	Curlin associated repeat; Region: Curlin_rpt; pfam07012
595495010711	Curlin associated repeat; Region: Curlin_rpt; pfam07012
595495010712	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
595495010713	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
595495010714	DNA binding residues [nucleotide binding]
595495010715	dimerization interface [polypeptide binding]; other site
595495010716	curli assembly protein CsgE; Provisional; Region: PRK10386
595495010717	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495010718	curli assembly protein CsgF; Provisional; Region: PRK10050
595495010719	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
595495010720	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
595495010721	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
595495010722	putative hydrolase; Validated; Region: PRK09248
595495010723	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
595495010724	active site
595495010725	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
595495010726	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
595495010727	putative ligand binding site [chemical binding]; other site
595495010728	NAD binding site [chemical binding]; other site
595495010729	dimerization interface [polypeptide binding]; other site
595495010730	catalytic site [active]
595495010731	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
595495010732	Transposase; Region: HTH_Tnp_1; cl17663
595495010733	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
595495010734	putative transposase OrfB; Reviewed; Region: PHA02517
595495010735	HTH-like domain; Region: HTH_21; pfam13276
595495010736	Integrase core domain; Region: rve; pfam00665
595495010737	Integrase core domain; Region: rve_2; pfam13333
595495010738	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
595495010739	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
595495010740	metal binding site [ion binding]; metal-binding site
595495010741	active site
595495010742	I-site; other site
595495010743	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495010744	outer membrane protein PgaA; Provisional; Region: pgaA; PRK10049
595495010745	outer membrane N-deacetylase; Provisional; Region: pgaB; PRK14582
595495010746	N-terminal putative catalytic polysaccharide deacetylase domain of bacterial poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, and similar proteins; Region: CE4_PgaB_5s; cd10964
595495010747	putative active site [active]
595495010748	putative metal binding site [ion binding]; other site
595495010749	N-glycosyltransferase; Provisional; Region: PRK11204
595495010750	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
595495010751	DXD motif; other site
595495010752	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
595495010753	putative PGA biosynthesis protein; Provisional; Region: pgaD; PRK14585
595495010754	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
595495010755	hypothetical protein; Provisional; Region: PRK10536
595495010756	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
595495010757	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
595495010758	inactive ferrous ion transporter periplasmic protein EfeO; Provisional; Region: PRK10378
595495010759	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
595495010760	Imelysin; Region: Peptidase_M75; pfam09375
595495010761	FTR1 family protein; Region: TIGR00145
595495010762	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
595495010763	Na binding site [ion binding]; other site
595495010764	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
595495010765	Predicted transcriptional regulator [Transcription]; Region: COG3905
595495010766	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
595495010767	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
595495010768	Glutamate binding site [chemical binding]; other site
595495010769	NAD binding site [chemical binding]; other site
595495010770	catalytic residues [active]
595495010771	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
595495010772	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
595495010773	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
595495010774	pyrimidine utilization protein A; Region: RutA; TIGR03612
595495010775	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
595495010776	active site
595495010777	dimer interface [polypeptide binding]; other site
595495010778	non-prolyl cis peptide bond; other site
595495010779	insertion regions; other site
595495010780	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
595495010781	Isochorismatase family; Region: Isochorismatase; pfam00857
595495010782	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
595495010783	catalytic triad [active]
595495010784	conserved cis-peptide bond; other site
595495010785	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
595495010786	homotrimer interaction site [polypeptide binding]; other site
595495010787	putative active site [active]
595495010788	pyrimidine utilization protein D; Region: RutD; TIGR03611
595495010789	Nitroreductase-like family 5.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_5; cd02148
595495010790	putative FMN binding site [chemical binding]; other site
595495010791	pyrimidine utilization flavin reductase protein F; Region: RutF; TIGR03615
595495010792	pyrimidine utilization transport protein G; Region: RutG; TIGR03616
595495010793	General stress protein [General function prediction only]; Region: GsiB; COG3729
595495010794	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
595495010795	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
595495010796	hypothetical protein; Provisional; Region: PRK10174
595495010797	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
595495010798	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
595495010799	catalytic core [active]
595495010800	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
595495010801	hypothetical protein; Provisional; Region: PRK09784
595495010802	hypothetical protein; Provisional; Region: PRK09784
595495010803	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
595495010804	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
595495010805	HSP70 interaction site [polypeptide binding]; other site
595495010806	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
595495010807	substrate binding site [polypeptide binding]; other site
595495010808	dimer interface [polypeptide binding]; other site
595495010809	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
595495010810	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
595495010811	chaperone protein TorD; Validated; Region: torD; PRK04976
595495010812	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
595495010813	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
595495010814	molybdopterin cofactor binding site [chemical binding]; other site
595495010815	substrate binding site [chemical binding]; other site
595495010816	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
595495010817	molybdopterin cofactor binding site; other site
595495010818	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
595495010819	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
595495010820	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
595495010821	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495010822	active site
595495010823	phosphorylation site [posttranslational modification]
595495010824	intermolecular recognition site; other site
595495010825	dimerization interface [polypeptide binding]; other site
595495010826	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
595495010827	DNA binding site [nucleotide binding]
595495010828	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
595495010829	TorT-like proteins, a periplasmic binding protein family that activates induction of the Tor respiratory system upon trimethylamine N-oxide (TMAO) electron-acceptor binding in bacteria; Region: PBP1_TorT-like; cd06306
595495010830	putative ligand binding site [chemical binding]; other site
595495010831	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
595495010832	HAMP domain; Region: HAMP; pfam00672
595495010833	dimerization interface [polypeptide binding]; other site
595495010834	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
595495010835	dimer interface [polypeptide binding]; other site
595495010836	phosphorylation site [posttranslational modification]
595495010837	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495010838	ATP binding site [chemical binding]; other site
595495010839	Mg2+ binding site [ion binding]; other site
595495010840	G-X-G motif; other site
595495010841	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495010842	active site
595495010843	phosphorylation site [posttranslational modification]
595495010844	intermolecular recognition site; other site
595495010845	dimerization interface [polypeptide binding]; other site
595495010846	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
595495010847	putative binding surface; other site
595495010848	active site
595495010849	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
595495010850	4Fe-4S binding domain; Region: Fer4_5; pfam12801
595495010851	4Fe-4S binding domain; Region: Fer4_5; pfam12801
595495010852	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
595495010853	GnsA/GnsB family; Region: GnsAB; pfam08178
595495010854	cold shock gene; Provisional; Region: PRK09891
595495010855	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
595495010856	DNA-binding site [nucleotide binding]; DNA binding site
595495010857	RNA-binding motif; other site
595495010858	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
595495010859	DNA-binding site [nucleotide binding]; DNA binding site
595495010860	RNA-binding motif; other site
595495010861	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
595495010862	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
595495010863	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
595495010864	polysaccharide export protein Wza; Provisional; Region: PRK15078
595495010865	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
595495010866	SLBB domain; Region: SLBB; pfam10531
595495010867	SLBB domain; Region: SLBB; pfam10531
595495010868	Low molecular weight phosphatase family; Region: LMWPc; cd00115
595495010869	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
595495010870	active site
595495010871	cryptic autophosphorylating protein tyrosine kinase Etk; Provisional; Region: PRK09841
595495010872	Chain length determinant protein; Region: Wzz; pfam02706
595495010873	Chain length determinant protein; Region: Wzz; cl15801
595495010874	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
595495010875	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
595495010876	Nucleotide binding site [chemical binding]; other site
595495010877	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
595495010878	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
595495010879	catalytic core [active]
595495010880	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
595495010881	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
595495010882	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
595495010883	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
595495010884	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
595495010885	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
595495010886	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
595495010887	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
595495010888	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
595495010889	putative substrate-binding site; other site
595495010890	nickel binding site [ion binding]; other site
595495010891	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
595495010892	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
595495010893	hydrogenase 1 large subunit; Provisional; Region: PRK10170
595495010894	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
595495010895	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
595495010896	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
595495010897	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
595495010898	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
595495010899	YccA-like proteins; Region: YccA_like; cd10433
595495010900	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
595495010901	sulfur transfer protein TusE; Provisional; Region: PRK11508
595495010902	Acylphosphatase; Region: Acylphosphatase; cl00551
595495010903	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
595495010904	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
595495010905	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
595495010906	putative RNA binding site [nucleotide binding]; other site
595495010907	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495010908	S-adenosylmethionine binding site [chemical binding]; other site
595495010909	heat shock protein HspQ; Provisional; Region: PRK14129
595495010910	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
595495010911	hypothetical protein; Provisional; Region: PRK03641
595495010912	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
595495010913	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
595495010914	active site
595495010915	dimer interfaces [polypeptide binding]; other site
595495010916	catalytic residues [active]
595495010917	DNA helicase IV; Provisional; Region: helD; PRK11054
595495010918	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
595495010919	Part of AAA domain; Region: AAA_19; pfam13245
595495010920	Family description; Region: UvrD_C_2; pfam13538
595495010921	Predicted membrane protein [Function unknown]; Region: COG3304
595495010922	Domain of unknown function (DUF307); Region: DUF307; pfam03733
595495010923	Domain of unknown function (DUF307); Region: DUF307; pfam03733
595495010924	TIGR01666 family membrane protein; Region: YCCS
595495010925	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
595495010926	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
595495010927	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
595495010928	TfoX C-terminal domain; Region: TfoX_C; pfam04994
595495010929	cell division inhibitor SulA; Region: sula; TIGR00623
595495010930	outer membrane protein A; Reviewed; Region: PRK10808
595495010931	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
595495010932	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
595495010933	ligand binding site [chemical binding]; other site
595495010934	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
595495010935	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
595495010936	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
595495010937	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
595495010938	active site 1 [active]
595495010939	dimer interface [polypeptide binding]; other site
595495010940	active site 2 [active]
595495010941	ribosome modulation factor; Provisional; Region: PRK14563
595495010942	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
595495010943	Protein of unknown function (DUF330); Region: DUF330; pfam03886
595495010944	paraquat-inducible protein B; Provisional; Region: PRK10807
595495010945	mce related protein; Region: MCE; pfam02470
595495010946	mce related protein; Region: MCE; pfam02470
595495010947	mce related protein; Region: MCE; pfam02470
595495010948	DASH complex subunit Duo1; Region: DASH_Duo1; pfam08651
595495010949	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
595495010950	Paraquat-inducible protein A; Region: PqiA; pfam04403
595495010951	Paraquat-inducible protein A; Region: PqiA; pfam04403
595495010952	ABC transporter ATPase component; Reviewed; Region: PRK11147
595495010953	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495010954	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495010955	Walker A/P-loop; other site
595495010956	Walker A/P-loop; other site
595495010957	ATP binding site [chemical binding]; other site
595495010958	ATP binding site [chemical binding]; other site
595495010959	Q-loop/lid; other site
595495010960	Q-loop/lid; other site
595495010961	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
595495010962	ABC transporter signature motif; other site
595495010963	Walker B; other site
595495010964	D-loop; other site
595495010965	ABC transporter; Region: ABC_tran_2; pfam12848
595495010966	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
595495010967	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
595495010968	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
595495010969	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
595495010970	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495010971	S-adenosylmethionine binding site [chemical binding]; other site
595495010972	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
595495010973	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
595495010974	MOSC domain; Region: MOSC; pfam03473
595495010975	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
595495010976	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
595495010977	catalytic loop [active]
595495010978	iron binding site [ion binding]; other site
595495010979	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
595495010980	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
595495010981	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
595495010982	quinone interaction residues [chemical binding]; other site
595495010983	active site
595495010984	catalytic residues [active]
595495010985	FMN binding site [chemical binding]; other site
595495010986	substrate binding site [chemical binding]; other site
595495010987	putativi pili assembly chaperone; Provisional; Region: PRK11385
595495010988	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
595495010989	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
595495010990	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
595495010991	Fimbrial protein; Region: Fimbrial; cl01416
595495010992	Fimbrial protein; Region: Fimbrial; cl01416
595495010993	outer membrane usher protein; Provisional; Region: PRK15193
595495010994	PapC N-terminal domain; Region: PapC_N; pfam13954
595495010995	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
595495010996	PapC C-terminal domain; Region: PapC_C; pfam13953
595495010997	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
595495010998	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
595495010999	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
595495011000	Fimbrial protein; Region: Fimbrial; cl01416
595495011001	NAD(P)H-dependent FMN reductase; Provisional; Region: PRK10569
595495011002	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
595495011003	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
595495011004	substrate binding pocket [chemical binding]; other site
595495011005	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
595495011006	membrane-bound complex binding site; other site
595495011007	hinge residues; other site
595495011008	alkanesulfonate monooxygenase; Provisional; Region: PRK00719
595495011009	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
595495011010	active site
595495011011	dimer interface [polypeptide binding]; other site
595495011012	non-prolyl cis peptide bond; other site
595495011013	insertion regions; other site
595495011014	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
595495011015	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495011016	dimer interface [polypeptide binding]; other site
595495011017	conserved gate region; other site
595495011018	putative PBP binding loops; other site
595495011019	ABC-ATPase subunit interface; other site
595495011020	aliphatic sulfonates transport ATP-binding subunit; Provisional; Region: ssuB; PRK11247
595495011021	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
595495011022	Walker A/P-loop; other site
595495011023	ATP binding site [chemical binding]; other site
595495011024	Q-loop/lid; other site
595495011025	ABC transporter signature motif; other site
595495011026	Walker B; other site
595495011027	D-loop; other site
595495011028	H-loop/switch region; other site
595495011029	aminopeptidase N; Provisional; Region: pepN; PRK14015
595495011030	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
595495011031	active site
595495011032	Zn binding site [ion binding]; other site
595495011033	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
595495011034	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
595495011035	active site
595495011036	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
595495011037	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
595495011038	putative dimer interface [polypeptide binding]; other site
595495011039	putative anticodon binding site; other site
595495011040	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
595495011041	homodimer interface [polypeptide binding]; other site
595495011042	motif 1; other site
595495011043	motif 2; other site
595495011044	active site
595495011045	motif 3; other site
595495011046	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
595495011047	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
595495011048	trimer interface [polypeptide binding]; other site
595495011049	eyelet of channel; other site
595495011050	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
595495011051	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
595495011052	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495011053	homodimer interface [polypeptide binding]; other site
595495011054	catalytic residue [active]
595495011055	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
595495011056	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
595495011057	Peptidase M15; Region: Peptidase_M15_3; cl01194
595495011058	murein L,D-transpeptidase; Provisional; Region: PRK10594
595495011059	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
595495011060	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
595495011061	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
595495011062	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
595495011063	MukB N-terminal; Region: MukB; pfam04310
595495011064	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
595495011065	condesin subunit E; Provisional; Region: PRK05256
595495011066	condesin subunit F; Provisional; Region: PRK05260
595495011067	Methyltransferase domain; Region: Methyltransf_31; pfam13847
595495011068	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495011069	S-adenosylmethionine binding site [chemical binding]; other site
595495011070	Uncharacterized conserved protein [Function unknown]; Region: COG1434
595495011071	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
595495011072	putative active site [active]
595495011073	hypothetical protein; Provisional; Region: PRK10593
595495011074	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
595495011075	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
595495011076	Ligand binding site; other site
595495011077	oligomer interface; other site
595495011078	hypothetical protein; Provisional; Region: PRK11827
595495011079	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
595495011080	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
595495011081	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
595495011082	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
595495011083	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
595495011084	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
595495011085	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
595495011086	Walker A/P-loop; other site
595495011087	ATP binding site [chemical binding]; other site
595495011088	Q-loop/lid; other site
595495011089	ABC transporter signature motif; other site
595495011090	Walker B; other site
595495011091	D-loop; other site
595495011092	H-loop/switch region; other site
595495011093	ComEC family competence protein; Provisional; Region: PRK11539
595495011094	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
595495011095	ComEC/Rec2-related protein; Region: ComEC_N-term; TIGR00360
595495011096	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
595495011097	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
595495011098	IHF dimer interface [polypeptide binding]; other site
595495011099	IHF - DNA interface [nucleotide binding]; other site
595495011100	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
595495011101	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
595495011102	RNA binding site [nucleotide binding]; other site
595495011103	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
595495011104	RNA binding site [nucleotide binding]; other site
595495011105	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
595495011106	RNA binding site [nucleotide binding]; other site
595495011107	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
595495011108	RNA binding site [nucleotide binding]; other site
595495011109	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
595495011110	RNA binding site [nucleotide binding]; other site
595495011111	cytidylate kinase; Provisional; Region: cmk; PRK00023
595495011112	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
595495011113	CMP-binding site; other site
595495011114	The sites determining sugar specificity; other site
595495011115	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
595495011116	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
595495011117	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
595495011118	hinge; other site
595495011119	active site
595495011120	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
595495011121	homodimer interface [polypeptide binding]; other site
595495011122	substrate-cofactor binding pocket; other site
595495011123	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495011124	catalytic residue [active]
595495011125	Predicted membrane protein [Function unknown]; Region: COG2323
595495011126	uncharacterized domain; Region: TIGR00702
595495011127	YcaO-like family; Region: YcaO; pfam02624
595495011128	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495011129	formate transporter; Provisional; Region: PRK10805
595495011130	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011131	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
595495011132	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
595495011133	dimer interface [polypeptide binding]; other site
595495011134	PYR/PP interface [polypeptide binding]; other site
595495011135	TPP binding site [chemical binding]; other site
595495011136	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495011137	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
595495011138	TPP-binding site [chemical binding]; other site
595495011139	dimer interface [polypeptide binding]; other site
595495011140	putative alcohol dehydrogenase; Provisional; Region: PRK09860
595495011141	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495011142	dimer interface [polypeptide binding]; other site
595495011143	active site
595495011144	metal binding site [ion binding]; metal-binding site
595495011145	chloramphenicol acetyltransferase; Provisional; Region: PRK13757
595495011146	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
595495011147	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011148	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
595495011149	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495011150	FeS/SAM binding site; other site
595495011151	YcaO domain protein; Region: TIGR03549
595495011152	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495011153	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011154	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
595495011155	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
595495011156	dimer interface [polypeptide binding]; other site
595495011157	PYR/PP interface [polypeptide binding]; other site
595495011158	TPP binding site [chemical binding]; other site
595495011159	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495011160	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
595495011161	TPP-binding site [chemical binding]; other site
595495011162	dimer interface [polypeptide binding]; other site
595495011163	putative alcohol dehydrogenase; Provisional; Region: PRK09860
595495011164	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495011165	dimer interface [polypeptide binding]; other site
595495011166	active site
595495011167	metal binding site [ion binding]; metal-binding site
595495011168	chloramphenicol acetyltransferase; Provisional; Region: PRK13757
595495011169	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
595495011170	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011171	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
595495011172	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495011173	FeS/SAM binding site; other site
595495011174	YcaO domain protein; Region: TIGR03549
595495011175	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495011176	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011177	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
595495011178	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
595495011179	dimer interface [polypeptide binding]; other site
595495011180	PYR/PP interface [polypeptide binding]; other site
595495011181	TPP binding site [chemical binding]; other site
595495011182	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495011183	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
595495011184	TPP-binding site [chemical binding]; other site
595495011185	dimer interface [polypeptide binding]; other site
595495011186	putative alcohol dehydrogenase; Provisional; Region: PRK09860
595495011187	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495011188	dimer interface [polypeptide binding]; other site
595495011189	active site
595495011190	metal binding site [ion binding]; metal-binding site
595495011191	chloramphenicol acetyltransferase; Provisional; Region: PRK13757
595495011192	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
595495011193	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011194	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
595495011195	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495011196	FeS/SAM binding site; other site
595495011197	YcaO domain protein; Region: TIGR03549
595495011198	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495011199	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011200	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
595495011201	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
595495011202	dimer interface [polypeptide binding]; other site
595495011203	PYR/PP interface [polypeptide binding]; other site
595495011204	TPP binding site [chemical binding]; other site
595495011205	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495011206	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
595495011207	TPP-binding site [chemical binding]; other site
595495011208	dimer interface [polypeptide binding]; other site
595495011209	putative alcohol dehydrogenase; Provisional; Region: PRK09860
595495011210	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495011211	dimer interface [polypeptide binding]; other site
595495011212	active site
595495011213	metal binding site [ion binding]; metal-binding site
595495011214	chloramphenicol acetyltransferase; Provisional; Region: PRK13757
595495011215	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
595495011216	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011217	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
595495011218	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495011219	FeS/SAM binding site; other site
595495011220	YcaO domain protein; Region: TIGR03549
595495011221	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495011222	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011223	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
595495011224	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
595495011225	dimer interface [polypeptide binding]; other site
595495011226	PYR/PP interface [polypeptide binding]; other site
595495011227	TPP binding site [chemical binding]; other site
595495011228	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495011229	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
595495011230	TPP-binding site [chemical binding]; other site
595495011231	dimer interface [polypeptide binding]; other site
595495011232	putative alcohol dehydrogenase; Provisional; Region: PRK09860
595495011233	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495011234	dimer interface [polypeptide binding]; other site
595495011235	active site
595495011236	metal binding site [ion binding]; metal-binding site
595495011237	chloramphenicol acetyltransferase; Provisional; Region: PRK13757
595495011238	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
595495011239	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011240	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
595495011241	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495011242	FeS/SAM binding site; other site
595495011243	YcaO domain protein; Region: TIGR03549
595495011244	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495011245	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011246	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
595495011247	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
595495011248	dimer interface [polypeptide binding]; other site
595495011249	PYR/PP interface [polypeptide binding]; other site
595495011250	TPP binding site [chemical binding]; other site
595495011251	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495011252	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
595495011253	TPP-binding site [chemical binding]; other site
595495011254	dimer interface [polypeptide binding]; other site
595495011255	putative alcohol dehydrogenase; Provisional; Region: PRK09860
595495011256	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495011257	dimer interface [polypeptide binding]; other site
595495011258	active site
595495011259	metal binding site [ion binding]; metal-binding site
595495011260	chloramphenicol acetyltransferase; Provisional; Region: PRK13757
595495011261	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
595495011262	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011263	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
595495011264	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495011265	FeS/SAM binding site; other site
595495011266	YcaO domain protein; Region: TIGR03549
595495011267	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495011268	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011269	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
595495011270	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
595495011271	dimer interface [polypeptide binding]; other site
595495011272	PYR/PP interface [polypeptide binding]; other site
595495011273	TPP binding site [chemical binding]; other site
595495011274	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495011275	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
595495011276	TPP-binding site [chemical binding]; other site
595495011277	dimer interface [polypeptide binding]; other site
595495011278	putative alcohol dehydrogenase; Provisional; Region: PRK09860
595495011279	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495011280	dimer interface [polypeptide binding]; other site
595495011281	active site
595495011282	metal binding site [ion binding]; metal-binding site
595495011283	chloramphenicol acetyltransferase; Provisional; Region: PRK13757
595495011284	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
595495011285	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011286	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
595495011287	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495011288	FeS/SAM binding site; other site
595495011289	YcaO domain protein; Region: TIGR03549
595495011290	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495011291	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011292	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
595495011293	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
595495011294	dimer interface [polypeptide binding]; other site
595495011295	PYR/PP interface [polypeptide binding]; other site
595495011296	TPP binding site [chemical binding]; other site
595495011297	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495011298	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
595495011299	TPP-binding site [chemical binding]; other site
595495011300	dimer interface [polypeptide binding]; other site
595495011301	putative alcohol dehydrogenase; Provisional; Region: PRK09860
595495011302	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495011303	dimer interface [polypeptide binding]; other site
595495011304	active site
595495011305	metal binding site [ion binding]; metal-binding site
595495011306	chloramphenicol acetyltransferase; Provisional; Region: PRK13757
595495011307	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
595495011308	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011309	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
595495011310	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495011311	FeS/SAM binding site; other site
595495011312	YcaO domain protein; Region: TIGR03549
595495011313	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495011314	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011315	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
595495011316	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
595495011317	dimer interface [polypeptide binding]; other site
595495011318	PYR/PP interface [polypeptide binding]; other site
595495011319	TPP binding site [chemical binding]; other site
595495011320	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495011321	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
595495011322	TPP-binding site [chemical binding]; other site
595495011323	dimer interface [polypeptide binding]; other site
595495011324	putative alcohol dehydrogenase; Provisional; Region: PRK09860
595495011325	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495011326	dimer interface [polypeptide binding]; other site
595495011327	active site
595495011328	metal binding site [ion binding]; metal-binding site
595495011329	chloramphenicol acetyltransferase; Provisional; Region: PRK13757
595495011330	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
595495011331	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011332	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
595495011333	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495011334	FeS/SAM binding site; other site
595495011335	YcaO domain protein; Region: TIGR03549
595495011336	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495011337	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011338	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
595495011339	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
595495011340	dimer interface [polypeptide binding]; other site
595495011341	PYR/PP interface [polypeptide binding]; other site
595495011342	TPP binding site [chemical binding]; other site
595495011343	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495011344	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
595495011345	TPP-binding site [chemical binding]; other site
595495011346	dimer interface [polypeptide binding]; other site
595495011347	putative alcohol dehydrogenase; Provisional; Region: PRK09860
595495011348	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495011349	dimer interface [polypeptide binding]; other site
595495011350	active site
595495011351	metal binding site [ion binding]; metal-binding site
595495011352	chloramphenicol acetyltransferase; Provisional; Region: PRK13757
595495011353	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
595495011354	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011355	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
595495011356	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495011357	FeS/SAM binding site; other site
595495011358	YcaO domain protein; Region: TIGR03549
595495011359	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495011360	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011361	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
595495011362	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
595495011363	dimer interface [polypeptide binding]; other site
595495011364	PYR/PP interface [polypeptide binding]; other site
595495011365	TPP binding site [chemical binding]; other site
595495011366	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495011367	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
595495011368	TPP-binding site [chemical binding]; other site
595495011369	dimer interface [polypeptide binding]; other site
595495011370	putative alcohol dehydrogenase; Provisional; Region: PRK09860
595495011371	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495011372	dimer interface [polypeptide binding]; other site
595495011373	active site
595495011374	metal binding site [ion binding]; metal-binding site
595495011375	chloramphenicol acetyltransferase; Provisional; Region: PRK13757
595495011376	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
595495011377	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011378	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
595495011379	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495011380	FeS/SAM binding site; other site
595495011381	YcaO domain protein; Region: TIGR03549
595495011382	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495011383	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011384	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
595495011385	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
595495011386	dimer interface [polypeptide binding]; other site
595495011387	PYR/PP interface [polypeptide binding]; other site
595495011388	TPP binding site [chemical binding]; other site
595495011389	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495011390	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
595495011391	TPP-binding site [chemical binding]; other site
595495011392	dimer interface [polypeptide binding]; other site
595495011393	putative alcohol dehydrogenase; Provisional; Region: PRK09860
595495011394	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495011395	dimer interface [polypeptide binding]; other site
595495011396	active site
595495011397	metal binding site [ion binding]; metal-binding site
595495011398	chloramphenicol acetyltransferase; Provisional; Region: PRK13757
595495011399	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
595495011400	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011401	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
595495011402	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495011403	FeS/SAM binding site; other site
595495011404	YcaO domain protein; Region: TIGR03549
595495011405	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495011406	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011407	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
595495011408	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
595495011409	dimer interface [polypeptide binding]; other site
595495011410	PYR/PP interface [polypeptide binding]; other site
595495011411	TPP binding site [chemical binding]; other site
595495011412	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495011413	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
595495011414	TPP-binding site [chemical binding]; other site
595495011415	dimer interface [polypeptide binding]; other site
595495011416	putative alcohol dehydrogenase; Provisional; Region: PRK09860
595495011417	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495011418	dimer interface [polypeptide binding]; other site
595495011419	active site
595495011420	metal binding site [ion binding]; metal-binding site
595495011421	chloramphenicol acetyltransferase; Provisional; Region: PRK13757
595495011422	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
595495011423	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011424	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
595495011425	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495011426	FeS/SAM binding site; other site
595495011427	YcaO domain protein; Region: TIGR03549
595495011428	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495011429	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011430	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
595495011431	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
595495011432	dimer interface [polypeptide binding]; other site
595495011433	PYR/PP interface [polypeptide binding]; other site
595495011434	TPP binding site [chemical binding]; other site
595495011435	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495011436	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
595495011437	TPP-binding site [chemical binding]; other site
595495011438	dimer interface [polypeptide binding]; other site
595495011439	putative alcohol dehydrogenase; Provisional; Region: PRK09860
595495011440	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495011441	dimer interface [polypeptide binding]; other site
595495011442	active site
595495011443	metal binding site [ion binding]; metal-binding site
595495011444	chloramphenicol acetyltransferase; Provisional; Region: PRK13757
595495011445	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
595495011446	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011447	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
595495011448	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495011449	FeS/SAM binding site; other site
595495011450	YcaO domain protein; Region: TIGR03549
595495011451	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495011452	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011453	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
595495011454	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
595495011455	dimer interface [polypeptide binding]; other site
595495011456	PYR/PP interface [polypeptide binding]; other site
595495011457	TPP binding site [chemical binding]; other site
595495011458	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495011459	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
595495011460	TPP-binding site [chemical binding]; other site
595495011461	dimer interface [polypeptide binding]; other site
595495011462	putative alcohol dehydrogenase; Provisional; Region: PRK09860
595495011463	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495011464	dimer interface [polypeptide binding]; other site
595495011465	active site
595495011466	metal binding site [ion binding]; metal-binding site
595495011467	chloramphenicol acetyltransferase; Provisional; Region: PRK13757
595495011468	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
595495011469	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011470	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
595495011471	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495011472	FeS/SAM binding site; other site
595495011473	YcaO domain protein; Region: TIGR03549
595495011474	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495011475	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011476	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
595495011477	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
595495011478	dimer interface [polypeptide binding]; other site
595495011479	PYR/PP interface [polypeptide binding]; other site
595495011480	TPP binding site [chemical binding]; other site
595495011481	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495011482	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
595495011483	TPP-binding site [chemical binding]; other site
595495011484	dimer interface [polypeptide binding]; other site
595495011485	putative alcohol dehydrogenase; Provisional; Region: PRK09860
595495011486	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495011487	dimer interface [polypeptide binding]; other site
595495011488	active site
595495011489	metal binding site [ion binding]; metal-binding site
595495011490	chloramphenicol acetyltransferase; Provisional; Region: PRK13757
595495011491	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
595495011492	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011493	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
595495011494	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495011495	FeS/SAM binding site; other site
595495011496	YcaO domain protein; Region: TIGR03549
595495011497	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495011498	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011499	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
595495011500	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
595495011501	dimer interface [polypeptide binding]; other site
595495011502	PYR/PP interface [polypeptide binding]; other site
595495011503	TPP binding site [chemical binding]; other site
595495011504	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495011505	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
595495011506	TPP-binding site [chemical binding]; other site
595495011507	dimer interface [polypeptide binding]; other site
595495011508	putative alcohol dehydrogenase; Provisional; Region: PRK09860
595495011509	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495011510	dimer interface [polypeptide binding]; other site
595495011511	active site
595495011512	metal binding site [ion binding]; metal-binding site
595495011513	chloramphenicol acetyltransferase; Provisional; Region: PRK13757
595495011514	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
595495011515	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011516	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
595495011517	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495011518	FeS/SAM binding site; other site
595495011519	YcaO domain protein; Region: TIGR03549
595495011520	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495011521	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011522	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
595495011523	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
595495011524	dimer interface [polypeptide binding]; other site
595495011525	PYR/PP interface [polypeptide binding]; other site
595495011526	TPP binding site [chemical binding]; other site
595495011527	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495011528	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
595495011529	TPP-binding site [chemical binding]; other site
595495011530	dimer interface [polypeptide binding]; other site
595495011531	putative alcohol dehydrogenase; Provisional; Region: PRK09860
595495011532	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495011533	dimer interface [polypeptide binding]; other site
595495011534	active site
595495011535	metal binding site [ion binding]; metal-binding site
595495011536	chloramphenicol acetyltransferase; Provisional; Region: PRK13757
595495011537	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
595495011538	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011539	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
595495011540	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495011541	FeS/SAM binding site; other site
595495011542	YcaO domain protein; Region: TIGR03549
595495011543	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495011544	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011545	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
595495011546	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
595495011547	dimer interface [polypeptide binding]; other site
595495011548	PYR/PP interface [polypeptide binding]; other site
595495011549	TPP binding site [chemical binding]; other site
595495011550	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495011551	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
595495011552	TPP-binding site [chemical binding]; other site
595495011553	dimer interface [polypeptide binding]; other site
595495011554	putative alcohol dehydrogenase; Provisional; Region: PRK09860
595495011555	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495011556	dimer interface [polypeptide binding]; other site
595495011557	active site
595495011558	metal binding site [ion binding]; metal-binding site
595495011559	chloramphenicol acetyltransferase; Provisional; Region: PRK13757
595495011560	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
595495011561	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011562	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
595495011563	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495011564	FeS/SAM binding site; other site
595495011565	YcaO domain protein; Region: TIGR03549
595495011566	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495011567	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011568	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
595495011569	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
595495011570	dimer interface [polypeptide binding]; other site
595495011571	PYR/PP interface [polypeptide binding]; other site
595495011572	TPP binding site [chemical binding]; other site
595495011573	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495011574	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
595495011575	TPP-binding site [chemical binding]; other site
595495011576	dimer interface [polypeptide binding]; other site
595495011577	putative alcohol dehydrogenase; Provisional; Region: PRK09860
595495011578	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
595495011579	dimer interface [polypeptide binding]; other site
595495011580	active site
595495011581	metal binding site [ion binding]; metal-binding site
595495011582	chloramphenicol acetyltransferase; Provisional; Region: PRK13757
595495011583	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
595495011584	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
595495011585	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
595495011586	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495011587	FeS/SAM binding site; other site
595495011588	hypothetical protein; Provisional; Region: PRK09739
595495011589	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
595495011590	Transcriptional regulator [Transcription]; Region: LysR; COG0583
595495011591	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495011592	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
595495011593	putative effector binding pocket; other site
595495011594	putative dimerization interface [polypeptide binding]; other site
595495011595	Amino acid permease; Region: AA_permease_2; pfam13520
595495011596	putative MFS family transporter protein; Provisional; Region: PRK03633
595495011597	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495011598	putative substrate translocation pore; other site
595495011599	Isochorismatase family; Region: Isochorismatase; pfam00857
595495011600	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
595495011601	catalytic triad [active]
595495011602	dimer interface [polypeptide binding]; other site
595495011603	conserved cis-peptide bond; other site
595495011604	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
595495011605	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
595495011606	4Fe-4S binding domain; Region: Fer4; pfam00037
595495011607	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
595495011608	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
595495011609	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
595495011610	putative [Fe4-S4] binding site [ion binding]; other site
595495011611	putative molybdopterin cofactor binding site [chemical binding]; other site
595495011612	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
595495011613	putative molybdopterin cofactor binding site; other site
595495011614	seryl-tRNA synthetase; Provisional; Region: PRK05431
595495011615	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
595495011616	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
595495011617	dimer interface [polypeptide binding]; other site
595495011618	active site
595495011619	motif 1; other site
595495011620	motif 2; other site
595495011621	motif 3; other site
595495011622	recombination factor protein RarA; Reviewed; Region: PRK13342
595495011623	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495011624	Walker A motif; other site
595495011625	ATP binding site [chemical binding]; other site
595495011626	Walker B motif; other site
595495011627	arginine finger; other site
595495011628	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
595495011629	periplasmic chaperone LolA; Region: lolA; TIGR00547
595495011630	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
595495011631	DNA translocase FtsK; Provisional; Region: PRK10263
595495011632	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
595495011633	DNA translocase FtsK; Provisional; Region: PRK10263
595495011634	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
595495011635	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
595495011636	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
595495011637	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
595495011638	putative DNA binding site [nucleotide binding]; other site
595495011639	putative Zn2+ binding site [ion binding]; other site
595495011640	AsnC family; Region: AsnC_trans_reg; pfam01037
595495011641	thioredoxin reductase; Provisional; Region: PRK10262
595495011642	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
595495011643	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
595495011644	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
595495011645	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
595495011646	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495011647	Walker A/P-loop; other site
595495011648	ATP binding site [chemical binding]; other site
595495011649	Q-loop/lid; other site
595495011650	ABC transporter signature motif; other site
595495011651	Walker B; other site
595495011652	D-loop; other site
595495011653	H-loop/switch region; other site
595495011654	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
595495011655	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
595495011656	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
595495011657	Walker A/P-loop; other site
595495011658	ATP binding site [chemical binding]; other site
595495011659	Q-loop/lid; other site
595495011660	ABC transporter signature motif; other site
595495011661	Walker B; other site
595495011662	D-loop; other site
595495011663	H-loop/switch region; other site
595495011664	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
595495011665	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
595495011666	rRNA binding site [nucleotide binding]; other site
595495011667	predicted 30S ribosome binding site; other site
595495011668	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
595495011669	Clp amino terminal domain; Region: Clp_N; pfam02861
595495011670	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495011671	Walker A motif; other site
595495011672	ATP binding site [chemical binding]; other site
595495011673	Walker B motif; other site
595495011674	arginine finger; other site
595495011675	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495011676	Walker A motif; other site
595495011677	ATP binding site [chemical binding]; other site
595495011678	Walker B motif; other site
595495011679	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
595495011680	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
595495011681	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
595495011682	DNA-binding site [nucleotide binding]; DNA binding site
595495011683	RNA-binding motif; other site
595495011684	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
595495011685	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
595495011686	Walker A/P-loop; other site
595495011687	ATP binding site [chemical binding]; other site
595495011688	Q-loop/lid; other site
595495011689	ABC transporter signature motif; other site
595495011690	Walker B; other site
595495011691	D-loop; other site
595495011692	H-loop/switch region; other site
595495011693	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
595495011694	FtsX-like permease family; Region: FtsX; pfam02687
595495011695	macrolide transporter subunit MacA; Provisional; Region: PRK11578
595495011696	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
595495011697	HlyD family secretion protein; Region: HlyD_3; pfam13437
595495011698	Protein of unknown function (DUF535); Region: DUF535; pfam04393
595495011699	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
595495011700	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
595495011701	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
595495011702	putative active site [active]
595495011703	putative metal-binding site [ion binding]; other site
595495011704	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
595495011705	amphipathic channel; other site
595495011706	Asn-Pro-Ala signature motifs; other site
595495011707	Predicted membrane protein [Function unknown]; Region: COG2431
595495011708	hybrid cluster protein; Provisional; Region: PRK05290
595495011709	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
595495011710	ACS interaction site; other site
595495011711	CODH interaction site; other site
595495011712	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
595495011713	hybrid metal cluster; other site
595495011714	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
595495011715	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
595495011716	FAD binding pocket [chemical binding]; other site
595495011717	FAD binding motif [chemical binding]; other site
595495011718	phosphate binding motif [ion binding]; other site
595495011719	beta-alpha-beta structure motif; other site
595495011720	NAD binding pocket [chemical binding]; other site
595495011721	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
595495011722	catalytic loop [active]
595495011723	iron binding site [ion binding]; other site
595495011724	pyruvate dehydrogenase; Provisional; Region: PRK09124
595495011725	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
595495011726	PYR/PP interface [polypeptide binding]; other site
595495011727	dimer interface [polypeptide binding]; other site
595495011728	tetramer interface [polypeptide binding]; other site
595495011729	TPP binding site [chemical binding]; other site
595495011730	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495011731	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
595495011732	TPP-binding site [chemical binding]; other site
595495011733	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
595495011734	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
595495011735	tetramer interface [polypeptide binding]; other site
595495011736	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495011737	catalytic residue [active]
595495011738	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
595495011739	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
595495011740	putative NAD(P) binding site [chemical binding]; other site
595495011741	putative active site [active]
595495011742	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
595495011743	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
595495011744	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
595495011745	NAD(P) binding site [chemical binding]; other site
595495011746	active site
595495011747	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
595495011748	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
595495011749	amidase catalytic site [active]
595495011750	Zn binding residues [ion binding]; other site
595495011751	substrate binding site [chemical binding]; other site
595495011752	hypothetical protein; Provisional; Region: PRK02877
595495011753	putative lipoprotein; Provisional; Region: PRK10533
595495011754	putative lipoprotein; Provisional; Region: PRK10533
595495011755	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
595495011756	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495011757	Walker A/P-loop; other site
595495011758	ATP binding site [chemical binding]; other site
595495011759	Q-loop/lid; other site
595495011760	ABC transporter signature motif; other site
595495011761	Walker B; other site
595495011762	D-loop; other site
595495011763	H-loop/switch region; other site
595495011764	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
595495011765	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
595495011766	substrate binding pocket [chemical binding]; other site
595495011767	membrane-bound complex binding site; other site
595495011768	hinge residues; other site
595495011769	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
595495011770	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495011771	dimer interface [polypeptide binding]; other site
595495011772	conserved gate region; other site
595495011773	putative PBP binding loops; other site
595495011774	ABC-ATPase subunit interface; other site
595495011775	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495011776	dimer interface [polypeptide binding]; other site
595495011777	conserved gate region; other site
595495011778	putative PBP binding loops; other site
595495011779	ABC-ATPase subunit interface; other site
595495011780	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
595495011781	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
595495011782	substrate binding pocket [chemical binding]; other site
595495011783	membrane-bound complex binding site; other site
595495011784	hinge residues; other site
595495011785	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
595495011786	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495011787	S-adenosylmethionine binding site [chemical binding]; other site
595495011788	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
595495011789	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
595495011790	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495011791	dimer interface [polypeptide binding]; other site
595495011792	conserved gate region; other site
595495011793	putative PBP binding loops; other site
595495011794	ABC-ATPase subunit interface; other site
595495011795	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
595495011796	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495011797	dimer interface [polypeptide binding]; other site
595495011798	conserved gate region; other site
595495011799	putative PBP binding loops; other site
595495011800	ABC-ATPase subunit interface; other site
595495011801	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
595495011802	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495011803	Walker A/P-loop; other site
595495011804	ATP binding site [chemical binding]; other site
595495011805	Q-loop/lid; other site
595495011806	ABC transporter signature motif; other site
595495011807	Walker B; other site
595495011808	D-loop; other site
595495011809	H-loop/switch region; other site
595495011810	TOBE domain; Region: TOBE_2; pfam08402
595495011811	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
595495011812	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
595495011813	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
595495011814	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
595495011815	RimK-like ATP-grasp domain; Region: RimK; pfam08443
595495011816	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
595495011817	dimer interface [polypeptide binding]; other site
595495011818	FMN binding site [chemical binding]; other site
595495011819	NADPH bind site [chemical binding]; other site
595495011820	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
595495011821	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
595495011822	GSH binding site [chemical binding]; other site
595495011823	catalytic residues [active]
595495011824	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
595495011825	putative transporter; Provisional; Region: PRK04972
595495011826	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
595495011827	TrkA-C domain; Region: TrkA_C; pfam02080
595495011828	TrkA-C domain; Region: TrkA_C; pfam02080
595495011829	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
595495011830	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
595495011831	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
595495011832	tail protein; Provisional; Region: D; PHA02561
595495011833	Phage protein U [General function prediction only]; Region: COG3499
595495011834	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
595495011835	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
595495011836	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
595495011837	major tail tube protein; Provisional; Region: FII; PHA02600
595495011838	major tail sheath protein; Provisional; Region: FI; PHA02560
595495011839	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
595495011840	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
595495011841	catalytic residues [active]
595495011842	catalytic nucleophile [active]
595495011843	Presynaptic Site I dimer interface [polypeptide binding]; other site
595495011844	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
595495011845	Synaptic Flat tetramer interface [polypeptide binding]; other site
595495011846	Synaptic Site I dimer interface [polypeptide binding]; other site
595495011847	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
595495011848	DNA-binding interface [nucleotide binding]; DNA binding site
595495011849	Phage Tail Collar Domain; Region: Collar; pfam07484
595495011850	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
595495011851	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
595495011852	Transposase; Region: HTH_Tnp_1; cl17663
595495011853	HTH-like domain; Region: HTH_21; pfam13276
595495011854	Integrase core domain; Region: rve; pfam00665
595495011855	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
595495011856	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
595495011857	baseplate assembly protein; Provisional; Region: J; PHA02568
595495011858	baseplate wedge subunit; Provisional; Region: W; PHA02516
595495011859	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
595495011860	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
595495011861	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
595495011862	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
595495011863	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
595495011864	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
595495011865	catalytic residues [active]
595495011866	P2-like prophage tail protein X [General function prediction only]; Region: COG5004
595495011867	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
595495011868	terminase endonuclease subunit; Provisional; Region: M; PHA02537
595495011869	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
595495011870	capsid protein; Provisional; Region: N; PHA02538
595495011871	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
595495011872	terminase ATPase subunit; Provisional; Region: P; PHA02535
595495011873	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
595495011874	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
595495011875	portal vertex protein; Provisional; Region: Q; PHA02536
595495011876	Phage portal protein; Region: Phage_portal; pfam04860
595495011877	Protein of unknown function DUF262; Region: DUF262; pfam03235
595495011878	Uncharacterized conserved protein [Function unknown]; Region: COG1479
595495011879	DinI-like family; Region: DinI; pfam06183
595495011880	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
595495011881	DNA adenine methylase (dam); Region: dam; TIGR00571
595495011882	DksA-like zinc finger domain containing protein; Region: PHA00080
595495011883	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
595495011884	Protein of unknown function (DUF2724); Region: DUF2724; pfam10893
595495011885	Phage regulatory protein CII (CP76); Region: Phage_CP76; pfam06892
595495011886	Helix-turn-helix domain; Region: HTH_17; cl17695
595495011887	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
595495011888	KAP family P-loop domain; Region: KAP_NTPase; pfam07693
595495011889	Predicted P-loop ATPase [General function prediction only]; Region: COG4928
595495011890	integrase; Provisional; Region: int; PHA02601
595495011891	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
595495011892	active site
595495011893	DNA binding site [nucleotide binding]
595495011894	Int/Topo IB signature motif; other site
595495011895	transcriptional repressor BetI; Region: betaine_BetI; TIGR03384
595495011896	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
595495011897	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
595495011898	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495011899	putative substrate translocation pore; other site
595495011900	Major Facilitator Superfamily; Region: MFS_1; pfam07690
595495011901	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
595495011902	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495011903	active site
595495011904	motif I; other site
595495011905	motif II; other site
595495011906	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495011907	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
595495011908	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
595495011909	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495011910	putative substrate translocation pore; other site
595495011911	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
595495011912	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
595495011913	active site
595495011914	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
595495011915	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
595495011916	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
595495011917	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
595495011918	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
595495011919	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
595495011920	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
595495011921	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
595495011922	putative C-terminal domain interface [polypeptide binding]; other site
595495011923	putative GSH binding site (G-site) [chemical binding]; other site
595495011924	putative dimer interface [polypeptide binding]; other site
595495011925	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
595495011926	N-terminal domain interface [polypeptide binding]; other site
595495011927	dimer interface [polypeptide binding]; other site
595495011928	substrate binding pocket (H-site) [chemical binding]; other site
595495011929	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
595495011930	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
595495011931	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
595495011932	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
595495011933	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
595495011934	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495011935	FeS/SAM binding site; other site
595495011936	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
595495011937	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
595495011938	metal binding site [ion binding]; metal-binding site
595495011939	active site
595495011940	I-site; other site
595495011941	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
595495011942	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
595495011943	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
595495011944	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495011945	dimer interface [polypeptide binding]; other site
595495011946	conserved gate region; other site
595495011947	putative PBP binding loops; other site
595495011948	ABC-ATPase subunit interface; other site
595495011949	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
595495011950	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495011951	dimer interface [polypeptide binding]; other site
595495011952	conserved gate region; other site
595495011953	putative PBP binding loops; other site
595495011954	ABC-ATPase subunit interface; other site
595495011955	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
595495011956	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
595495011957	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
595495011958	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
595495011959	Walker A/P-loop; other site
595495011960	ATP binding site [chemical binding]; other site
595495011961	Q-loop/lid; other site
595495011962	ABC transporter signature motif; other site
595495011963	Walker B; other site
595495011964	D-loop; other site
595495011965	H-loop/switch region; other site
595495011966	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
595495011967	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
595495011968	Walker A/P-loop; other site
595495011969	ATP binding site [chemical binding]; other site
595495011970	Q-loop/lid; other site
595495011971	ABC transporter signature motif; other site
595495011972	Walker B; other site
595495011973	D-loop; other site
595495011974	H-loop/switch region; other site
595495011975	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
595495011976	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
595495011977	catalytic nucleophile [active]
595495011978	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
595495011979	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
595495011980	dimer interface [polypeptide binding]; other site
595495011981	putative functional site; other site
595495011982	putative MPT binding site; other site
595495011983	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
595495011984	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
595495011985	ATP binding site [chemical binding]; other site
595495011986	substrate interface [chemical binding]; other site
595495011987	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
595495011988	active site
595495011989	intersubunit interactions; other site
595495011990	catalytic residue [active]
595495011991	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
595495011992	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
595495011993	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
595495011994	dimer interface [polypeptide binding]; other site
595495011995	active site
595495011996	glycine loop; other site
595495011997	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
595495011998	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495011999	active site
595495012000	motif I; other site
595495012001	motif II; other site
595495012002	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495012003	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
595495012004	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
595495012005	Transposase; Region: DEDD_Tnp_IS110; pfam01548
595495012006	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
595495012007	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
595495012008	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495012009	Walker A/P-loop; other site
595495012010	ATP binding site [chemical binding]; other site
595495012011	Q-loop/lid; other site
595495012012	ABC transporter signature motif; other site
595495012013	Walker B; other site
595495012014	D-loop; other site
595495012015	H-loop/switch region; other site
595495012016	ABC transporter; Region: ABC_tran_2; pfam12848
595495012017	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
595495012018	L,D-transpeptidase; Provisional; Region: PRK10260
595495012019	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
595495012020	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
595495012021	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
595495012022	transmembrane helices; other site
595495012023	manganese transport regulator MntR; Provisional; Region: PRK11050
595495012024	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
595495012025	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
595495012026	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
595495012027	Sulfatase; Region: Sulfatase; pfam00884
595495012028	outer membrane protein X; Provisional; Region: ompX; PRK09408
595495012029	threonine and homoserine efflux system; Provisional; Region: PRK10532
595495012030	EamA-like transporter family; Region: EamA; pfam00892
595495012031	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
595495012032	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
595495012033	dimerization interface [polypeptide binding]; other site
595495012034	DPS ferroxidase diiron center [ion binding]; other site
595495012035	ion pore; other site
595495012036	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
595495012037	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
595495012038	substrate binding pocket [chemical binding]; other site
595495012039	membrane-bound complex binding site; other site
595495012040	hinge residues; other site
595495012041	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
595495012042	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495012043	dimer interface [polypeptide binding]; other site
595495012044	conserved gate region; other site
595495012045	putative PBP binding loops; other site
595495012046	ABC-ATPase subunit interface; other site
595495012047	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
595495012048	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
595495012049	Walker A/P-loop; other site
595495012050	ATP binding site [chemical binding]; other site
595495012051	Q-loop/lid; other site
595495012052	ABC transporter signature motif; other site
595495012053	Walker B; other site
595495012054	D-loop; other site
595495012055	H-loop/switch region; other site
595495012056	putative mechanosensitive channel protein; Provisional; Region: PRK11465
595495012057	Mechanosensitive ion channel; Region: MS_channel; pfam00924
595495012058	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
595495012059	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
595495012060	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
595495012061	catecholate siderophore receptor Fiu; Provisional; Region: PRK09840
595495012062	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
595495012063	N-terminal plug; other site
595495012064	ligand-binding site [chemical binding]; other site
595495012065	Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467
595495012066	hypothetical protein; Provisional; Region: PRK11019
595495012067	hypothetical protein; Provisional; Region: PRK10259
595495012068	putative dehydrogenase; Provisional; Region: PRK10098
595495012069	glycosyl transferase family protein; Provisional; Region: PRK08136
595495012070	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
595495012071	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
595495012072	DEAD_2; Region: DEAD_2; pfam06733
595495012073	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
595495012074	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3236
595495012075	helicase 45; Provisional; Region: PTZ00424
595495012076	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
595495012077	ATP binding site [chemical binding]; other site
595495012078	Mg++ binding site [ion binding]; other site
595495012079	motif III; other site
595495012080	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
595495012081	nucleotide binding region [chemical binding]; other site
595495012082	ATP-binding site [chemical binding]; other site
595495012083	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
595495012084	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
595495012085	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
595495012086	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
595495012087	HlyD family secretion protein; Region: HlyD_3; pfam13437
595495012088	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
595495012089	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
595495012090	Walker A/P-loop; other site
595495012091	ATP binding site [chemical binding]; other site
595495012092	Q-loop/lid; other site
595495012093	ABC transporter signature motif; other site
595495012094	Walker B; other site
595495012095	D-loop; other site
595495012096	H-loop/switch region; other site
595495012097	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
595495012098	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
595495012099	Walker A/P-loop; other site
595495012100	ATP binding site [chemical binding]; other site
595495012101	Q-loop/lid; other site
595495012102	ABC transporter signature motif; other site
595495012103	Walker B; other site
595495012104	D-loop; other site
595495012105	H-loop/switch region; other site
595495012106	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
595495012107	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
595495012108	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
595495012109	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
595495012110	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
595495012111	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
595495012112	putative catalytic site [active]
595495012113	putative metal binding site [ion binding]; other site
595495012114	putative phosphate binding site [ion binding]; other site
595495012115	cardiolipin synthase 2; Provisional; Region: PRK11263
595495012116	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
595495012117	putative active site [active]
595495012118	catalytic site [active]
595495012119	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
595495012120	putative active site [active]
595495012121	catalytic site [active]
595495012122	Predicted integral membrane protein [Function unknown]; Region: COG0392
595495012123	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
595495012124	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
595495012125	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
595495012126	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
595495012127	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
595495012128	MoaE homodimer interface [polypeptide binding]; other site
595495012129	MoaD interaction [polypeptide binding]; other site
595495012130	active site residues [active]
595495012131	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
595495012132	MoaE interaction surface [polypeptide binding]; other site
595495012133	MoeB interaction surface [polypeptide binding]; other site
595495012134	thiocarboxylated glycine; other site
595495012135	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
595495012136	trimer interface [polypeptide binding]; other site
595495012137	dimer interface [polypeptide binding]; other site
595495012138	putative active site [active]
595495012139	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
595495012140	MPT binding site; other site
595495012141	trimer interface [polypeptide binding]; other site
595495012142	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
595495012143	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495012144	FeS/SAM binding site; other site
595495012145	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
595495012146	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
595495012147	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
595495012148	putative substrate binding pocket [chemical binding]; other site
595495012149	dimer interface [polypeptide binding]; other site
595495012150	phosphate binding site [ion binding]; other site
595495012151	excinuclease ABC subunit B; Provisional; Region: PRK05298
595495012152	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
595495012153	ATP binding site [chemical binding]; other site
595495012154	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
595495012155	nucleotide binding region [chemical binding]; other site
595495012156	ATP-binding site [chemical binding]; other site
595495012157	Ultra-violet resistance protein B; Region: UvrB; pfam12344
595495012158	UvrB/uvrC motif; Region: UVR; pfam02151
595495012159	AAA domain; Region: AAA_26; pfam13500
595495012160	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
595495012161	Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and...; Region: DTBS; cd03109
595495012162	ADP binding site [chemical binding]; other site
595495012163	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
595495012164	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495012165	S-adenosylmethionine binding site [chemical binding]; other site
595495012166	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
595495012167	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
595495012168	substrate-cofactor binding pocket; other site
595495012169	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495012170	catalytic residue [active]
595495012171	biotin synthase; Provisional; Region: PRK15108
595495012172	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495012173	FeS/SAM binding site; other site
595495012174	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
595495012175	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
595495012176	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
595495012177	inhibitor-cofactor binding pocket; inhibition site
595495012178	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495012179	catalytic residue [active]
595495012180	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
595495012181	substrate binding site [chemical binding]; other site
595495012182	acyl-CoA thioesterase; Provisional; Region: PRK10531
595495012183	putative pectinesterase; Region: PLN02432; cl01911
595495012184	putative hydratase; Provisional; Region: PRK11413
595495012185	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
595495012186	substrate binding site [chemical binding]; other site
595495012187	ligand binding site [chemical binding]; other site
595495012188	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
595495012189	substrate binding site [chemical binding]; other site
595495012190	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
595495012191	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
595495012192	transmembrane helices; other site
595495012193	PrpF protein; Region: PrpF; pfam04303
595495012194	Transcriptional regulator [Transcription]; Region: LysR; COG0583
595495012195	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495012196	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
595495012197	putative dimerization interface [polypeptide binding]; other site
595495012198	6-phosphogluconolactonase; Provisional; Region: PRK11028
595495012199	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
595495012200	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495012201	motif II; other site
595495012202	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495012203	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
595495012204	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495012205	Walker A/P-loop; other site
595495012206	ATP binding site [chemical binding]; other site
595495012207	Q-loop/lid; other site
595495012208	ABC transporter signature motif; other site
595495012209	Walker B; other site
595495012210	D-loop; other site
595495012211	H-loop/switch region; other site
595495012212	molybdenum-pterin binding domain; Region: Mop; TIGR00638
595495012213	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
595495012214	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495012215	putative PBP binding loops; other site
595495012216	ABC-ATPase subunit interface; other site
595495012217	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
595495012218	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
595495012219	substrate binding pocket [chemical binding]; other site
595495012220	membrane-bound complex binding site; other site
595495012221	hinge residues; other site
595495012222	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
595495012223	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
595495012224	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
595495012225	molybdenum-pterin binding domain; Region: Mop; TIGR00638
595495012226	TOBE domain; Region: TOBE; pfam03459
595495012227	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
595495012228	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
595495012229	Walker A/P-loop; other site
595495012230	ATP binding site [chemical binding]; other site
595495012231	Q-loop/lid; other site
595495012232	ABC transporter signature motif; other site
595495012233	Walker B; other site
595495012234	D-loop; other site
595495012235	H-loop/switch region; other site
595495012236	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495012237	Walker A/P-loop; other site
595495012238	ATP binding site [chemical binding]; other site
595495012239	Q-loop/lid; other site
595495012240	ABC transporter signature motif; other site
595495012241	Walker B; other site
595495012242	D-loop; other site
595495012243	H-loop/switch region; other site
595495012244	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
595495012245	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
595495012246	NAD binding site [chemical binding]; other site
595495012247	homodimer interface [polypeptide binding]; other site
595495012248	active site
595495012249	substrate binding site [chemical binding]; other site
595495012250	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
595495012251	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
595495012252	dimer interface [polypeptide binding]; other site
595495012253	active site
595495012254	galactokinase; Provisional; Region: PRK05101
595495012255	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
595495012256	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
595495012257	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
595495012258	active site
595495012259	catalytic residues [active]
595495012260	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
595495012261	catalytic core [active]
595495012262	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
595495012263	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
595495012264	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
595495012265	YbgS-like protein; Region: YbgS; pfam13985
595495012266	zinc transporter ZitB; Provisional; Region: PRK03557
595495012267	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
595495012268	quinolinate synthetase; Provisional; Region: PRK09375
595495012269	tol-pal system protein YbgF; Provisional; Region: PRK10803
595495012270	Tetratricopeptide repeat; Region: TPR_6; pfam13174
595495012271	Tetratricopeptide repeat; Region: TPR_6; pfam13174
595495012272	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
595495012273	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
595495012274	ligand binding site [chemical binding]; other site
595495012275	translocation protein TolB; Provisional; Region: tolB; PRK03629
595495012276	TolB amino-terminal domain; Region: TolB_N; pfam04052
595495012277	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
595495012278	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
595495012279	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
595495012280	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
595495012281	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
595495012282	TolA C-terminal; Region: TolA; pfam06519
595495012283	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
595495012284	colicin uptake protein TolR; Provisional; Region: PRK11024
595495012285	colicin uptake protein TolQ; Provisional; Region: PRK10801
595495012286	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
595495012287	active site
595495012288	hypothetical protein; Provisional; Region: PRK10588
595495012289	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
595495012290	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
595495012291	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
595495012292	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
595495012293	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
595495012294	alpha-mannosidase; Provisional; Region: PRK09819
595495012295	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
595495012296	active site
595495012297	metal binding site [ion binding]; metal-binding site
595495012298	catalytic site [active]
595495012299	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
595495012300	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
595495012301	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
595495012302	active site
595495012303	phosphorylation site [posttranslational modification]
595495012304	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
595495012305	active site
595495012306	P-loop; other site
595495012307	phosphorylation site [posttranslational modification]
595495012308	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
595495012309	DNA-binding transcriptional repressor MngR; Provisional; Region: PRK09764
595495012310	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
595495012311	DNA-binding site [nucleotide binding]; DNA binding site
595495012312	UTRA domain; Region: UTRA; pfam07702
595495012313	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
595495012314	CoA binding domain; Region: CoA_binding; smart00881
595495012315	CoA-ligase; Region: Ligase_CoA; pfam00549
595495012316	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
595495012317	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
595495012318	CoA-ligase; Region: Ligase_CoA; pfam00549
595495012319	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
595495012320	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
595495012321	E3 interaction surface; other site
595495012322	lipoyl attachment site [posttranslational modification]; other site
595495012323	e3 binding domain; Region: E3_binding; pfam02817
595495012324	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
595495012325	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
595495012326	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
595495012327	TPP-binding site [chemical binding]; other site
595495012328	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
595495012329	dimer interface [polypeptide binding]; other site
595495012330	PYR/PP interface [polypeptide binding]; other site
595495012331	TPP binding site [chemical binding]; other site
595495012332	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
595495012333	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
595495012334	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
595495012335	L-aspartate oxidase; Provisional; Region: PRK06175
595495012336	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
595495012337	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
595495012338	SdhC subunit interface [polypeptide binding]; other site
595495012339	proximal heme binding site [chemical binding]; other site
595495012340	cardiolipin binding site; other site
595495012341	Iron-sulfur protein interface; other site
595495012342	proximal quinone binding site [chemical binding]; other site
595495012343	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
595495012344	Iron-sulfur protein interface; other site
595495012345	proximal quinone binding site [chemical binding]; other site
595495012346	SdhD (CybS) interface [polypeptide binding]; other site
595495012347	proximal heme binding site [chemical binding]; other site
595495012348	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
595495012349	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
595495012350	dimer interface [polypeptide binding]; other site
595495012351	active site
595495012352	citrylCoA binding site [chemical binding]; other site
595495012353	NADH binding [chemical binding]; other site
595495012354	cationic pore residues; other site
595495012355	oxalacetate/citrate binding site [chemical binding]; other site
595495012356	coenzyme A binding site [chemical binding]; other site
595495012357	catalytic triad [active]
595495012358	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
595495012359	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
595495012360	PapC N-terminal domain; Region: PapC_N; pfam13954
595495012361	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
595495012362	PapC C-terminal domain; Region: PapC_C; pfam13953
595495012363	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
595495012364	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
595495012365	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
595495012366	Fimbrial protein; Region: Fimbrial; pfam00419
595495012367	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
595495012368	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
595495012369	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
595495012370	endonuclease VIII; Provisional; Region: PRK10445
595495012371	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
595495012372	DNA binding site [nucleotide binding]
595495012373	catalytic residue [active]
595495012374	putative catalytic residues [active]
595495012375	H2TH interface [polypeptide binding]; other site
595495012376	intercalation triad [nucleotide binding]; other site
595495012377	substrate specificity determining residue; other site
595495012378	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
595495012379	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
595495012380	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
595495012381	putative active site [active]
595495012382	biotin-dependent carboxylase uncharacterized domain; Region: urea_amlyse_rel; TIGR00724
595495012383	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
595495012384	sensor histidine kinase inhibitor, KipI family; Region: TIGR00370
595495012385	Uncharacterized conserved protein [Function unknown]; Region: COG0327
595495012386	metal-binding protein; Provisional; Region: PRK10799
595495012387	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
595495012388	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495012389	putative substrate translocation pore; other site
595495012390	POT family; Region: PTR2; pfam00854
595495012391	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
595495012392	DNA photolyase; Region: DNA_photolyase; pfam00875
595495012393	hypothetical protein; Provisional; Region: PRK10167
595495012394	Uncharacterized conserved protein [Function unknown]; Region: COG3272
595495012395	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
595495012396	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495012397	Transposase [DNA replication, recombination, and repair]; Region: COG5433
595495012398	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
595495012399	PAAR motif; Region: PAAR_motif; cl15808
595495012400	RHS Repeat; Region: RHS_repeat; pfam05593
595495012401	RHS Repeat; Region: RHS_repeat; pfam05593
595495012402	RHS Repeat; Region: RHS_repeat; cl11982
595495012403	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
595495012404	RHS Repeat; Region: RHS_repeat; pfam05593
595495012405	RHS Repeat; Region: RHS_repeat; pfam05593
595495012406	RHS protein; Region: RHS; pfam03527
595495012407	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
595495012408	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
595495012409	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
595495012410	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
595495012411	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
595495012412	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
595495012413	sensor protein KdpD; Provisional; Region: PRK10490
595495012414	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
595495012415	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
595495012416	Ligand Binding Site [chemical binding]; other site
595495012417	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
595495012418	GAF domain; Region: GAF_3; pfam13492
595495012419	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
595495012420	dimer interface [polypeptide binding]; other site
595495012421	phosphorylation site [posttranslational modification]
595495012422	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495012423	ATP binding site [chemical binding]; other site
595495012424	Mg2+ binding site [ion binding]; other site
595495012425	G-X-G motif; other site
595495012426	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
595495012427	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495012428	active site
595495012429	phosphorylation site [posttranslational modification]
595495012430	intermolecular recognition site; other site
595495012431	dimerization interface [polypeptide binding]; other site
595495012432	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
595495012433	DNA binding site [nucleotide binding]
595495012434	ornithine decarboxylase; Provisional; Region: PRK13578
595495012435	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
595495012436	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
595495012437	homodimer interface [polypeptide binding]; other site
595495012438	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495012439	catalytic residue [active]
595495012440	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
595495012441	putrescine transporter; Provisional; Region: potE; PRK10655
595495012442	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
595495012443	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
595495012444	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
595495012445	active site
595495012446	substrate binding site [chemical binding]; other site
595495012447	metal binding site [ion binding]; metal-binding site
595495012448	replication initiation regulator SeqA; Provisional; Region: PRK11187
595495012449	acyl-CoA esterase; Provisional; Region: PRK10673
595495012450	PGAP1-like protein; Region: PGAP1; pfam07819
595495012451	LexA regulated protein; Provisional; Region: PRK11675
595495012452	flavodoxin FldA; Validated; Region: PRK09267
595495012453	ferric uptake regulator; Provisional; Region: fur; PRK09462
595495012454	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
595495012455	metal binding site 2 [ion binding]; metal-binding site
595495012456	putative DNA binding helix; other site
595495012457	metal binding site 1 [ion binding]; metal-binding site
595495012458	dimer interface [polypeptide binding]; other site
595495012459	structural Zn2+ binding site [ion binding]; other site
595495012460	YbfN-like lipoprotein; Region: YbfN; pfam13982
595495012461	outer membrane porin, OprD family; Region: OprD; pfam03573
595495012462	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
595495012463	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
595495012464	active site
595495012465	HIGH motif; other site
595495012466	nucleotide binding site [chemical binding]; other site
595495012467	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
595495012468	KMSKS motif; other site
595495012469	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
595495012470	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
595495012471	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
595495012472	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
595495012473	active site turn [active]
595495012474	phosphorylation site [posttranslational modification]
595495012475	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
595495012476	HPr interaction site; other site
595495012477	glycerol kinase (GK) interaction site [polypeptide binding]; other site
595495012478	active site
595495012479	phosphorylation site [posttranslational modification]
595495012480	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
595495012481	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
595495012482	active site
595495012483	trimer interface [polypeptide binding]; other site
595495012484	allosteric site; other site
595495012485	active site lid [active]
595495012486	hexamer (dimer of trimers) interface [polypeptide binding]; other site
595495012487	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
595495012488	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
595495012489	active site
595495012490	dimer interface [polypeptide binding]; other site
595495012491	MarR family; Region: MarR; pfam01047
595495012492	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
595495012493	ROK family; Region: ROK; pfam00480
595495012494	UMP phosphatase; Provisional; Region: PRK10444
595495012495	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495012496	active site
595495012497	motif I; other site
595495012498	motif II; other site
595495012499	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495012500	asparagine synthetase B; Provisional; Region: asnB; PRK09431
595495012501	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
595495012502	active site
595495012503	dimer interface [polypeptide binding]; other site
595495012504	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
595495012505	Ligand Binding Site [chemical binding]; other site
595495012506	Molecular Tunnel; other site
595495012507	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
595495012508	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
595495012509	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
595495012510	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
595495012511	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495012512	FeS/SAM binding site; other site
595495012513	TRAM domain; Region: TRAM; pfam01938
595495012514	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
595495012515	PhoH-like protein; Region: PhoH; pfam02562
595495012516	metal-binding heat shock protein; Provisional; Region: PRK00016
595495012517	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
595495012518	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
595495012519	Transporter associated domain; Region: CorC_HlyC; smart01091
595495012520	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
595495012521	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
595495012522	putative active site [active]
595495012523	catalytic triad [active]
595495012524	putative dimer interface [polypeptide binding]; other site
595495012525	potential frameshift: common BLAST hit: gi|260866804|ref|YP_003233206.1| rhomboid family protein
595495012526	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
595495012527	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
595495012528	substrate binding pocket [chemical binding]; other site
595495012529	membrane-bound complex binding site; other site
595495012530	hinge residues; other site
595495012531	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
595495012532	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495012533	dimer interface [polypeptide binding]; other site
595495012534	conserved gate region; other site
595495012535	putative PBP binding loops; other site
595495012536	ABC-ATPase subunit interface; other site
595495012537	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
595495012538	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495012539	dimer interface [polypeptide binding]; other site
595495012540	conserved gate region; other site
595495012541	putative PBP binding loops; other site
595495012542	ABC-ATPase subunit interface; other site
595495012543	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
595495012544	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
595495012545	Walker A/P-loop; other site
595495012546	ATP binding site [chemical binding]; other site
595495012547	Q-loop/lid; other site
595495012548	ABC transporter signature motif; other site
595495012549	Walker B; other site
595495012550	D-loop; other site
595495012551	H-loop/switch region; other site
595495012552	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
595495012553	active site
595495012554	tetramer interface [polypeptide binding]; other site
595495012555	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
595495012556	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
595495012557	nucleotide binding site [chemical binding]; other site
595495012558	putative NEF/HSP70 interaction site [polypeptide binding]; other site
595495012559	SBD interface [polypeptide binding]; other site
595495012560	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cl02542
595495012561	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
595495012562	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
595495012563	Sel1-like repeats; Region: SEL1; smart00671
595495012564	Sel1-like repeats; Region: SEL1; smart00671
595495012565	Sel1-like repeats; Region: SEL1; smart00671
595495012566	DnaJ molecular chaperone homology domain; Region: DnaJ; smart00271
595495012567	HSP70 interaction site [polypeptide binding]; other site
595495012568	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
595495012569	Sel1-like repeats; Region: SEL1; smart00671
595495012570	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
595495012571	Sel1-like repeats; Region: SEL1; smart00671
595495012572	Sel1-like repeats; Region: SEL1; smart00671
595495012573	Sel1-like repeats; Region: SEL1; smart00671
595495012574	Sel1-like repeats; Region: SEL1; smart00671
595495012575	Sel1-like repeats; Region: SEL1; smart00671
595495012576	Sel1-like repeats; Region: SEL1; smart00671
595495012577	hypothetical protein; Provisional; Region: PRK11032
595495012578	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
595495012579	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
595495012580	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
595495012581	HIGH motif; other site
595495012582	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
595495012583	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
595495012584	active site
595495012585	KMSKS motif; other site
595495012586	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
595495012587	tRNA binding surface [nucleotide binding]; other site
595495012588	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
595495012589	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
595495012590	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
595495012591	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
595495012592	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
595495012593	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
595495012594	active site
595495012595	(T/H)XGH motif; other site
595495012596	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
595495012597	catalytic core [active]
595495012598	ribosome-associated protein; Provisional; Region: PRK11538
595495012599	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
595495012600	penicillin-binding protein 2; Provisional; Region: PRK10795
595495012601	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
595495012602	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
595495012603	cell wall shape-determining protein; Provisional; Region: PRK10794
595495012604	rare lipoprotein A; Provisional; Region: PRK10672
595495012605	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
595495012606	Sporulation related domain; Region: SPOR; pfam05036
595495012607	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
595495012608	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
595495012609	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
595495012610	hypothetical protein; Provisional; Region: PRK04998
595495012611	lipoate-protein ligase B; Provisional; Region: PRK14342
595495012612	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
595495012613	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495012614	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
595495012615	substrate binding pocket [chemical binding]; other site
595495012616	dimerization interface [polypeptide binding]; other site
595495012617	lipoyl synthase; Provisional; Region: PRK05481
595495012618	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495012619	FeS/SAM binding site; other site
595495012620	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
595495012621	Predicted amidohydrolase [General function prediction only]; Region: COG0388
595495012622	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
595495012623	putative active site [active]
595495012624	catalytic triad [active]
595495012625	putative dimer interface [polypeptide binding]; other site
595495012626	chromosome condensation membrane protein; Provisional; Region: PRK14196
595495012627	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
595495012628	DNA-binding site [nucleotide binding]; DNA binding site
595495012629	RNA-binding motif; other site
595495012630	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
595495012631	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
595495012632	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
595495012633	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
595495012634	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495012635	active site
595495012636	phosphorylation site [posttranslational modification]
595495012637	intermolecular recognition site; other site
595495012638	dimerization interface [polypeptide binding]; other site
595495012639	Transcriptional regulator; Region: CitT; pfam12431
595495012640	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
595495012641	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
595495012642	putative active site [active]
595495012643	heme pocket [chemical binding]; other site
595495012644	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495012645	ATP binding site [chemical binding]; other site
595495012646	Mg2+ binding site [ion binding]; other site
595495012647	G-X-G motif; other site
595495012648	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
595495012649	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
595495012650	putative active site [active]
595495012651	(T/H)XGH motif; other site
595495012652	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
595495012653	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
595495012654	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
595495012655	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
595495012656	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
595495012657	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
595495012658	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
595495012659	transmembrane helices; other site
595495012660	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
595495012661	B1 nucleotide binding pocket [chemical binding]; other site
595495012662	B2 nucleotide binding pocket [chemical binding]; other site
595495012663	CAS motifs; other site
595495012664	active site
595495012665	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
595495012666	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
595495012667	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
595495012668	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
595495012669	NAD binding site [chemical binding]; other site
595495012670	catalytic Zn binding site [ion binding]; other site
595495012671	structural Zn binding site [ion binding]; other site
595495012672	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
595495012673	Ligand Binding Site [chemical binding]; other site
595495012674	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
595495012675	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
595495012676	catalytic residue [active]
595495012677	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
595495012678	catalytic residues [active]
595495012679	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
595495012680	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
595495012681	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
595495012682	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
595495012683	dimer interface [polypeptide binding]; other site
595495012684	decamer (pentamer of dimers) interface [polypeptide binding]; other site
595495012685	catalytic triad [active]
595495012686	peroxidatic and resolving cysteines [active]
595495012687	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
595495012688	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
595495012689	dimerization domain [polypeptide binding]; other site
595495012690	dimer interface [polypeptide binding]; other site
595495012691	catalytic residues [active]
595495012692	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
595495012693	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495012694	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
595495012695	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
595495012696	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
595495012697	Active Sites [active]
595495012698	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
595495012699	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
595495012700	ParB-like nuclease domain; Region: ParBc; pfam02195
595495012701	methionine aminotransferase; Validated; Region: PRK09082
595495012702	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
595495012703	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495012704	homodimer interface [polypeptide binding]; other site
595495012705	catalytic residue [active]
595495012706	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
595495012707	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
595495012708	putative active site [active]
595495012709	metal binding site [ion binding]; metal-binding site
595495012710	Uncharacterized small protein [Function unknown]; Region: COG2879
595495012711	carbon starvation protein A; Provisional; Region: PRK15015
595495012712	Carbon starvation protein CstA; Region: CstA; pfam02554
595495012713	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
595495012714	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
595495012715	CoenzymeA binding site [chemical binding]; other site
595495012716	subunit interaction site [polypeptide binding]; other site
595495012717	PHB binding site; other site
595495012718	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
595495012719	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
595495012720	putative NAD(P) binding site [chemical binding]; other site
595495012721	active site
595495012722	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
595495012723	hydrophobic substrate binding pocket; other site
595495012724	Isochorismatase family; Region: Isochorismatase; pfam00857
595495012725	active site
595495012726	conserved cis-peptide bond; other site
595495012727	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
595495012728	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
595495012729	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
595495012730	acyl-activating enzyme (AAE) consensus motif; other site
595495012731	active site
595495012732	AMP binding site [chemical binding]; other site
595495012733	substrate binding site [chemical binding]; other site
595495012734	isochorismate synthase EntC; Provisional; Region: PRK15016
595495012735	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
595495012736	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
595495012737	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
595495012738	siderophore binding site; other site
595495012739	enterobactin exporter EntS; Provisional; Region: PRK10489
595495012740	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495012741	putative substrate translocation pore; other site
595495012742	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
595495012743	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
595495012744	ABC-ATPase subunit  interface; other site
595495012745	dimer interface [polypeptide binding]; other site
595495012746	putative PBP binding regions; other site
595495012747	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
595495012748	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
595495012749	ABC-ATPase subunit  interface; other site
595495012750	dimer interface [polypeptide binding]; other site
595495012751	putative PBP binding regions; other site
595495012752	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
595495012753	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
595495012754	Walker A/P-loop; other site
595495012755	ATP binding site [chemical binding]; other site
595495012756	Q-loop/lid; other site
595495012757	ABC transporter signature motif; other site
595495012758	Walker B; other site
595495012759	D-loop; other site
595495012760	H-loop/switch region; other site
595495012761	LPS O-antigen length regulator; Provisional; Region: PRK10381
595495012762	Chain length determinant protein; Region: Wzz; pfam02706
595495012763	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
595495012764	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
595495012765	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
595495012766	acyl-activating enzyme (AAE) consensus motif; other site
595495012767	AMP binding site [chemical binding]; other site
595495012768	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
595495012769	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
595495012770	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
595495012771	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
595495012772	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
595495012773	outer membrane receptor FepA; Provisional; Region: PRK13524
595495012774	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
595495012775	N-terminal plug; other site
595495012776	ligand-binding site [chemical binding]; other site
595495012777	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
595495012778	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
595495012779	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
595495012780	Hok/gef family; Region: HOK_GEF; pfam01848
595495012781	Hok/gef family; Region: HOK_GEF; pfam01848
595495012782	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
595495012783	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
595495012784	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
595495012785	hypothetical protein; Provisional; Region: PRK10250
595495012786	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
595495012787	dimer interface [polypeptide binding]; other site
595495012788	FMN binding site [chemical binding]; other site
595495012789	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
595495012790	Mechanosensitive ion channel; Region: MS_channel; pfam00924
595495012791	phenylalanine transporter; Provisional; Region: PRK10249
595495012792	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
595495012793	copper/silver efflux system membrane fusion protein CusB; Provisional; Region: PRK09783
595495012794	HlyD family secretion protein; Region: HlyD_3; pfam13437
595495012795	periplasmic copper-binding protein; Provisional; Region: PRK09838
595495012796	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
595495012797	DNA-binding transcriptional activator CusR; Provisional; Region: PRK09836
595495012798	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495012799	active site
595495012800	phosphorylation site [posttranslational modification]
595495012801	intermolecular recognition site; other site
595495012802	dimerization interface [polypeptide binding]; other site
595495012803	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
595495012804	DNA binding site [nucleotide binding]
595495012805	sensor kinase CusS; Provisional; Region: PRK09835
595495012806	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
595495012807	dimerization interface [polypeptide binding]; other site
595495012808	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
595495012809	dimer interface [polypeptide binding]; other site
595495012810	phosphorylation site [posttranslational modification]
595495012811	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495012812	ATP binding site [chemical binding]; other site
595495012813	Mg2+ binding site [ion binding]; other site
595495012814	G-X-G motif; other site
595495012815	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
595495012816	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
595495012817	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
595495012818	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
595495012819	Uncharacterized conserved protein [Function unknown]; Region: COG5435
595495012820	PAAR motif; Region: PAAR_motif; pfam05488
595495012821	RHS Repeat; Region: RHS_repeat; cl11982
595495012822	RHS Repeat; Region: RHS_repeat; pfam05593
595495012823	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
595495012824	RHS Repeat; Region: RHS_repeat; pfam05593
595495012825	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
595495012826	RHS Repeat; Region: RHS_repeat; pfam05593
595495012827	RHS Repeat; Region: RHS_repeat; cl11982
595495012828	RHS Repeat; Region: RHS_repeat; pfam05593
595495012829	RHS Repeat; Region: RHS_repeat; cl11982
595495012830	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
595495012831	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
595495012832	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
595495012833	RHS Repeat; Region: RHS_repeat; cl11982
595495012834	RHS Repeat; Region: RHS_repeat; cl11982
595495012835	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
595495012836	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
595495012837	RHS Repeat; Region: RHS_repeat; cl11982
595495012838	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
595495012839	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
595495012840	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495012841	Transposase [DNA replication, recombination, and repair]; Region: COG5433
595495012842	Transposase [DNA replication, recombination, and repair]; Region: COG5433
595495012843	bacteriophage N4 adsorption protein B; Provisional; Region: nfrB; PRK11234
595495012844	active site
595495012845	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
595495012846	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
595495012847	bacteriophage N4 receptor, outer membrane subunit; Provisional; Region: PRK09782
595495012848	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
595495012849	TPR motif; other site
595495012850	binding surface
595495012851	Bacteriophage N adsorption protein A C-term; Region: NfrA_C; pfam13283
595495012852	hypothetical protein; Provisional; Region: PRK09936
595495012853	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
595495012854	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495012855	transcriptional regulator FimZ; Provisional; Region: PRK09935
595495012856	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495012857	active site
595495012858	phosphorylation site [posttranslational modification]
595495012859	intermolecular recognition site; other site
595495012860	dimerization interface [polypeptide binding]; other site
595495012861	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
595495012862	DNA binding residues [nucleotide binding]
595495012863	dimerization interface [polypeptide binding]; other site
595495012864	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
595495012865	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
595495012866	PapC C-terminal domain; Region: PapC_C; pfam13953
595495012867	outer membrane usher protein FimD; Provisional; Region: PRK15198
595495012868	PapC N-terminal domain; Region: PapC_N; pfam13954
595495012869	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
595495012870	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
595495012871	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
595495012872	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
595495012873	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
595495012874	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
595495012875	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
595495012876	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
595495012877	homodimer interface [polypeptide binding]; other site
595495012878	NADP binding site [chemical binding]; other site
595495012879	substrate binding site [chemical binding]; other site
595495012880	ribosome-associated protein; Provisional; Region: PRK11507
595495012881	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
595495012882	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
595495012883	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
595495012884	active site
595495012885	HIGH motif; other site
595495012886	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
595495012887	KMSKS motif; other site
595495012888	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
595495012889	tRNA binding surface [nucleotide binding]; other site
595495012890	anticodon binding site; other site
595495012891	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
595495012892	substrate binding site [chemical binding]; other site
595495012893	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
595495012894	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
595495012895	putative active site [active]
595495012896	putative metal binding site [ion binding]; other site
595495012897	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
595495012898	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
595495012899	ATP-grasp domain; Region: ATP-grasp; pfam02222
595495012900	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
595495012901	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
595495012902	putative substrate binding site [chemical binding]; other site
595495012903	nucleotide binding site [chemical binding]; other site
595495012904	nucleotide binding site [chemical binding]; other site
595495012905	homodimer interface [polypeptide binding]; other site
595495012906	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
595495012907	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
595495012908	membrane protein FdrA; Validated; Region: PRK06091
595495012909	CoA binding domain; Region: CoA_binding; pfam02629
595495012910	CoA-ligase; Region: Ligase_CoA; pfam00549
595495012911	ureidoglycolate dehydrogenase; Provisional; Region: PRK15025
595495012912	allantoate amidohydrolase; Region: AllC; TIGR03176
595495012913	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
595495012914	active site
595495012915	metal binding site [ion binding]; metal-binding site
595495012916	dimer interface [polypeptide binding]; other site
595495012917	Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only]; Region: GlxB; COG3257
595495012918	Protein of unknown function (DUF861); Region: Cupin_3; pfam05899
595495012919	Cupin domain; Region: Cupin_2; cl17218
595495012920	glycerate kinase II; Provisional; Region: PRK09932
595495012921	putative uracil/xanthine transporter; Provisional; Region: PRK11412
595495012922	allantoinase; Provisional; Region: PRK08044
595495012923	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
595495012924	active site
595495012925	nucleobase-cation-symport-1 (NCS1) transporters; solute-binding domain; Region: SLC-NCS1sbd; cd10323
595495012926	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
595495012927	Na binding site [ion binding]; other site
595495012928	substrate binding site [chemical binding]; other site
595495012929	tartronate semialdehyde reductase; Provisional; Region: PRK15059
595495012930	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
595495012931	hydroxypyruvate isomerase; Provisional; Region: PRK09997
595495012932	glyoxylate carboligase; Provisional; Region: PRK11269
595495012933	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
595495012934	PYR/PP interface [polypeptide binding]; other site
595495012935	dimer interface [polypeptide binding]; other site
595495012936	TPP binding site [chemical binding]; other site
595495012937	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
595495012938	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
595495012939	TPP-binding site [chemical binding]; other site
595495012940	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
595495012941	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
595495012942	Bacterial transcriptional regulator; Region: IclR; pfam01614
595495012943	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
595495012944	ureidoglycolate hydrolase; Provisional; Region: PRK03606
595495012945	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
595495012946	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495012947	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
595495012948	dimerization interface [polypeptide binding]; other site
595495012949	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
595495012950	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
595495012951	active site residue [active]
595495012952	Winged helix-turn helix; Region: HTH_29; pfam13551
595495012953	Helix-turn-helix domain; Region: HTH_28; pfam13518
595495012954	hypothetical protein; Provisional; Region: PRK14710
595495012955	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
595495012956	RHS protein; Region: RHS; pfam03527
595495012957	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
595495012958	PAAR motif; Region: PAAR_motif; cl15808
595495012959	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
595495012960	RHS Repeat; Region: RHS_repeat; pfam05593
595495012961	RHS Repeat; Region: RHS_repeat; pfam05593
595495012962	RHS Repeat; Region: RHS_repeat; pfam05593
595495012963	RHS Repeat; Region: RHS_repeat; pfam05593
595495012964	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
595495012965	RHS Repeat; Region: RHS_repeat; pfam05593
595495012966	RHS Repeat; Region: RHS_repeat; pfam05593
595495012967	RHS protein; Region: RHS; pfam03527
595495012968	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
595495012969	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
595495012970	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
595495012971	FtsX-like permease family; Region: FtsX; pfam02687
595495012972	FtsX-like permease family; Region: FtsX; pfam02687
595495012973	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
595495012974	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
595495012975	Walker A/P-loop; other site
595495012976	ATP binding site [chemical binding]; other site
595495012977	Q-loop/lid; other site
595495012978	ABC transporter signature motif; other site
595495012979	Walker B; other site
595495012980	D-loop; other site
595495012981	H-loop/switch region; other site
595495012982	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
595495012983	active site
595495012984	catalytic triad [active]
595495012985	oxyanion hole [active]
595495012986	switch loop; other site
595495012987	oxidoreductase; Provisional; Region: PRK08017
595495012988	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
595495012989	NADP binding site [chemical binding]; other site
595495012990	active site
595495012991	steroid binding site; other site
595495012992	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
595495012993	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
595495012994	Uncharacterized protein family (UPF0014); Region: UPF0014; pfam03649
595495012995	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
595495012996	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495012997	Walker A/P-loop; other site
595495012998	ATP binding site [chemical binding]; other site
595495012999	Q-loop/lid; other site
595495013000	ABC transporter signature motif; other site
595495013001	Walker B; other site
595495013002	D-loop; other site
595495013003	H-loop/switch region; other site
595495013004	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
595495013005	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
595495013006	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
595495013007	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
595495013008	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
595495013009	DNA binding residues [nucleotide binding]
595495013010	dimer interface [polypeptide binding]; other site
595495013011	copper binding site [ion binding]; other site
595495013012	amino acid transporter; Region: 2A0306; TIGR00909
595495013013	glutaminase; Reviewed; Region: PRK12356
595495013014	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
595495013015	copper exporting ATPase; Provisional; Region: copA; PRK10671
595495013016	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
595495013017	metal-binding site [ion binding]
595495013018	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
595495013019	metal-binding site [ion binding]
595495013020	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
595495013021	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495013022	motif II; other site
595495013023	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
595495013024	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
595495013025	non-specific DNA binding site [nucleotide binding]; other site
595495013026	salt bridge; other site
595495013027	sequence-specific DNA binding site [nucleotide binding]; other site
595495013028	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
595495013029	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
595495013030	putative deacylase active site [active]
595495013031	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
595495013032	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
595495013033	active site
595495013034	metal binding site [ion binding]; metal-binding site
595495013035	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
595495013036	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495013037	Major Facilitator Superfamily; Region: MFS_1; pfam07690
595495013038	putative substrate translocation pore; other site
595495013039	putative cation:proton antiport protein; Provisional; Region: PRK10669
595495013040	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
595495013041	TrkA-N domain; Region: TrkA_N; pfam02254
595495013042	inosine/guanosine kinase; Provisional; Region: PRK15074
595495013043	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
595495013044	acetyl esterase; Provisional; Region: PRK10162
595495013045	ferrochelatase; Region: hemH; TIGR00109
595495013046	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
595495013047	C-terminal domain interface [polypeptide binding]; other site
595495013048	active site
595495013049	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
595495013050	active site
595495013051	N-terminal domain interface [polypeptide binding]; other site
595495013052	adenylate kinase; Reviewed; Region: adk; PRK00279
595495013053	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
595495013054	AMP-binding site [chemical binding]; other site
595495013055	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
595495013056	heat shock protein 90; Provisional; Region: PRK05218
595495013057	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495013058	ATP binding site [chemical binding]; other site
595495013059	Mg2+ binding site [ion binding]; other site
595495013060	G-X-G motif; other site
595495013061	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecR; COG0353
595495013062	RecR protein; Region: RecR; pfam02132
595495013063	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
595495013064	putative active site [active]
595495013065	putative metal-binding site [ion binding]; other site
595495013066	tetramer interface [polypeptide binding]; other site
595495013067	hypothetical protein; Validated; Region: PRK00153
595495013068	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
595495013069	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495013070	Walker A motif; other site
595495013071	ATP binding site [chemical binding]; other site
595495013072	Walker B motif; other site
595495013073	DNA polymerase III subunit delta'; Validated; Region: PRK08485
595495013074	arginine finger; other site
595495013075	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
595495013076	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
595495013077	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
595495013078	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
595495013079	active site
595495013080	hypothetical protein; Provisional; Region: PRK10527
595495013081	primosomal replication protein N''; Provisional; Region: PRK10093
595495013082	hypothetical protein; Provisional; Region: PRK11038
595495013083	hypothetical protein; Provisional; Region: PRK11281
595495013084	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
595495013085	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
595495013086	Mechanosensitive ion channel; Region: MS_channel; pfam00924
595495013087	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
595495013088	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
595495013089	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
595495013090	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
595495013091	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
595495013092	HlyD family secretion protein; Region: HlyD_3; pfam13437
595495013093	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
595495013094	Protein export membrane protein; Region: SecD_SecF; cl14618
595495013095	Protein export membrane protein; Region: SecD_SecF; cl14618
595495013096	Biofilm formation regulator YbaJ; Region: YbaJ; pfam10757
595495013097	gene expression modulator; Provisional; Region: PRK10945
595495013098	maltose O-acetyltransferase; Provisional; Region: PRK10092
595495013099	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
595495013100	active site
595495013101	substrate binding site [chemical binding]; other site
595495013102	trimer interface [polypeptide binding]; other site
595495013103	CoA binding site [chemical binding]; other site
595495013104	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
595495013105	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
595495013106	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
595495013107	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
595495013108	Uncharacterized conserved protein [Function unknown]; Region: COG5507
595495013109	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
595495013110	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
595495013111	DNA binding site [nucleotide binding]
595495013112	active site
595495013113	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
595495013114	acyl-CoA thioesterase II; Provisional; Region: PRK10526
595495013115	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
595495013116	active site
595495013117	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
595495013118	catalytic triad [active]
595495013119	dimer interface [polypeptide binding]; other site
595495013120	ammonium transporter; Provisional; Region: PRK10666
595495013121	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
595495013122	Nitrogen regulatory protein P-II; Region: P-II; smart00938
595495013123	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
595495013124	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
595495013125	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
595495013126	Walker A/P-loop; other site
595495013127	ATP binding site [chemical binding]; other site
595495013128	Q-loop/lid; other site
595495013129	ABC transporter signature motif; other site
595495013130	Walker B; other site
595495013131	D-loop; other site
595495013132	H-loop/switch region; other site
595495013133	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
595495013134	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
595495013135	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495013136	Walker A/P-loop; other site
595495013137	ATP binding site [chemical binding]; other site
595495013138	Q-loop/lid; other site
595495013139	ABC transporter signature motif; other site
595495013140	Walker B; other site
595495013141	D-loop; other site
595495013142	H-loop/switch region; other site
595495013143	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
595495013144	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
595495013145	putative DNA binding site [nucleotide binding]; other site
595495013146	putative Zn2+ binding site [ion binding]; other site
595495013147	AsnC family; Region: AsnC_trans_reg; pfam01037
595495013148	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
595495013149	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495013150	active site
595495013151	motif I; other site
595495013152	motif II; other site
595495013153	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
595495013154	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
595495013155	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
595495013156	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
595495013157	Ligand Binding Site [chemical binding]; other site
595495013158	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
595495013159	active site
595495013160	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
595495013161	periplasmic folding chaperone; Provisional; Region: PRK10788
595495013162	SurA N-terminal domain; Region: SurA_N_3; cl07813
595495013163	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
595495013164	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
595495013165	IHF dimer interface [polypeptide binding]; other site
595495013166	IHF - DNA interface [nucleotide binding]; other site
595495013167	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
595495013168	Found in ATP-dependent protease La (LON); Region: LON; smart00464
595495013169	Found in ATP-dependent protease La (LON); Region: LON; smart00464
595495013170	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495013171	Walker A motif; other site
595495013172	ATP binding site [chemical binding]; other site
595495013173	Walker B motif; other site
595495013174	arginine finger; other site
595495013175	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
595495013176	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
595495013177	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
595495013178	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495013179	Walker A motif; other site
595495013180	ATP binding site [chemical binding]; other site
595495013181	Walker B motif; other site
595495013182	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
595495013183	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
595495013184	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
595495013185	oligomer interface [polypeptide binding]; other site
595495013186	active site residues [active]
595495013187	trigger factor; Provisional; Region: tig; PRK01490
595495013188	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
595495013189	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
595495013190	transcriptional regulator BolA; Provisional; Region: PRK11628
595495013191	hypothetical protein; Provisional; Region: PRK11627
595495013192	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
595495013193	muropeptide transporter; Reviewed; Region: ampG; PRK11902
595495013194	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495013195	putative substrate translocation pore; other site
595495013196	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
595495013197	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
595495013198	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
595495013199	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
595495013200	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
595495013201	D-pathway; other site
595495013202	Putative ubiquinol binding site [chemical binding]; other site
595495013203	Low-spin heme (heme b) binding site [chemical binding]; other site
595495013204	Putative water exit pathway; other site
595495013205	Binuclear center (heme o3/CuB) [ion binding]; other site
595495013206	K-pathway; other site
595495013207	Putative proton exit pathway; other site
595495013208	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
595495013209	Subunit III/IV interface [polypeptide binding]; other site
595495013210	Subunit I/III interface [polypeptide binding]; other site
595495013211	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
595495013212	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
595495013213	UbiA prenyltransferase family; Region: UbiA; pfam01040
595495013214	Protein of unknown function (DUF1778); Region: DUF1778; pfam08681
595495013215	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
595495013216	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
595495013217	Sel1 repeat; Region: Sel1; pfam08238
595495013218	Sel1-like repeats; Region: SEL1; smart00671
595495013219	Sel1-like repeats; Region: SEL1; smart00671
595495013220	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495013221	Major Facilitator Superfamily; Region: MFS_1; pfam07690
595495013222	putative substrate translocation pore; other site
595495013223	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
595495013224	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
595495013225	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
595495013226	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
595495013227	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
595495013228	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
595495013229	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
595495013230	conserved cys residue [active]
595495013231	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
595495013232	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
595495013233	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
595495013234	Ligand Binding Site [chemical binding]; other site
595495013235	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
595495013236	active site residue [active]
595495013237	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
595495013238	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
595495013239	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
595495013240	substrate binding pocket [chemical binding]; other site
595495013241	chain length determination region; other site
595495013242	substrate-Mg2+ binding site; other site
595495013243	catalytic residues [active]
595495013244	aspartate-rich region 1; other site
595495013245	active site lid residues [active]
595495013246	aspartate-rich region 2; other site
595495013247	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
595495013248	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
595495013249	TPP-binding site; other site
595495013250	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
595495013251	PYR/PP interface [polypeptide binding]; other site
595495013252	dimer interface [polypeptide binding]; other site
595495013253	TPP binding site [chemical binding]; other site
595495013254	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
595495013255	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
595495013256	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
595495013257	active site
595495013258	catalytic tetrad [active]
595495013259	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
595495013260	tetramer interfaces [polypeptide binding]; other site
595495013261	binuclear metal-binding site [ion binding]; other site
595495013262	thiamine monophosphate kinase; Provisional; Region: PRK05731
595495013263	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
595495013264	ATP binding site [chemical binding]; other site
595495013265	dimerization interface [polypeptide binding]; other site
595495013266	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
595495013267	putative RNA binding site [nucleotide binding]; other site
595495013268	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
595495013269	homopentamer interface [polypeptide binding]; other site
595495013270	active site
595495013271	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
595495013272	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
595495013273	catalytic motif [active]
595495013274	Zn binding site [ion binding]; other site
595495013275	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
595495013276	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
595495013277	ATP cone domain; Region: ATP-cone; pfam03477
595495013278	hypothetical protein; Provisional; Region: PRK11530
595495013279	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
595495013280	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
595495013281	active site
595495013282	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
595495013283	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
595495013284	Protein export membrane protein; Region: SecD_SecF; pfam02355
595495013285	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
595495013286	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
595495013287	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
595495013288	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
595495013289	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
595495013290	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
595495013291	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
595495013292	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
595495013293	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
595495013294	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
595495013295	maltodextrin glucosidase; Provisional; Region: PRK10785
595495013296	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
595495013297	homodimer interface [polypeptide binding]; other site
595495013298	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
595495013299	active site
595495013300	homodimer interface [polypeptide binding]; other site
595495013301	catalytic site [active]
595495013302	putative proline-specific permease; Provisional; Region: proY; PRK10580
595495013303	Spore germination protein; Region: Spore_permease; cl17796
595495013304	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
595495013305	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
595495013306	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
595495013307	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
595495013308	putative active site [active]
595495013309	heme pocket [chemical binding]; other site
595495013310	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
595495013311	dimer interface [polypeptide binding]; other site
595495013312	phosphorylation site [posttranslational modification]
595495013313	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495013314	ATP binding site [chemical binding]; other site
595495013315	Mg2+ binding site [ion binding]; other site
595495013316	G-X-G motif; other site
595495013317	transcriptional regulator PhoB; Provisional; Region: PRK10161
595495013318	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495013319	active site
595495013320	phosphorylation site [posttranslational modification]
595495013321	intermolecular recognition site; other site
595495013322	dimerization interface [polypeptide binding]; other site
595495013323	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
595495013324	DNA binding site [nucleotide binding]
595495013325	exonuclease subunit SbcD; Provisional; Region: PRK10966
595495013326	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
595495013327	active site
595495013328	metal binding site [ion binding]; metal-binding site
595495013329	DNA binding site [nucleotide binding]
595495013330	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
595495013331	exonuclease subunit SbcC; Provisional; Region: PRK10246
595495013332	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495013333	Walker A/P-loop; other site
595495013334	ATP binding site [chemical binding]; other site
595495013335	Q-loop/lid; other site
595495013336	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495013337	ABC transporter signature motif; other site
595495013338	Walker B; other site
595495013339	D-loop; other site
595495013340	H-loop/switch region; other site
595495013341	MFS transport protein AraJ; Provisional; Region: PRK10091
595495013342	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495013343	putative substrate translocation pore; other site
595495013344	fructokinase; Reviewed; Region: PRK09557
595495013345	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
595495013346	nucleotide binding site [chemical binding]; other site
595495013347	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
595495013348	Protein of unknown function (DUF2773); Region: DUF2773; pfam10971
595495013349	hypothetical protein; Provisional; Region: PRK10579
595495013350	hypothetical protein; Provisional; Region: PRK10481
595495013351	hypothetical protein; Provisional; Region: PRK10380
595495013352	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
595495013353	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
595495013354	ADP binding site [chemical binding]; other site
595495013355	magnesium binding site [ion binding]; other site
595495013356	putative shikimate binding site; other site
595495013357	hypothetical protein; Validated; Region: PRK00124
595495013358	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
595495013359	pyrroline-5-carboxylate reductase; Region: PLN02688
595495013360	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
595495013361	MASE2 domain; Region: MASE2; pfam05230
595495013362	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
595495013363	metal binding site [ion binding]; metal-binding site
595495013364	active site
595495013365	I-site; other site
595495013366	hypothetical protein; Provisional; Region: PRK11505
595495013367	psiF repeat; Region: PsiF_repeat; pfam07769
595495013368	psiF repeat; Region: PsiF_repeat; pfam07769
595495013369	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
595495013370	dimer interface [polypeptide binding]; other site
595495013371	Alkaline phosphatase homologues; Region: alkPPc; smart00098
595495013372	active site
595495013373	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495013374	alkaline phosphatase; Provisional; Region: PRK10518
595495013375	anti-RssB factor; Provisional; Region: PRK10244
595495013376	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
595495013377	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
595495013378	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
595495013379	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
595495013380	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
595495013381	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
595495013382	microcin B17 transporter; Reviewed; Region: PRK11098
595495013383	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
595495013384	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
595495013385	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
595495013386	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
595495013387	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
595495013388	Autotransporter beta-domain; Region: Autotransporter; pfam03797
595495013389	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
595495013390	dimer interface [polypeptide binding]; other site
595495013391	active site
595495013392	Schiff base residues; other site
595495013393	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
595495013394	taurine dioxygenase; Reviewed; Region: tauD; PRK09553
595495013395	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
595495013396	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
595495013397	dimer interface [polypeptide binding]; other site
595495013398	conserved gate region; other site
595495013399	putative PBP binding loops; other site
595495013400	ABC-ATPase subunit interface; other site
595495013401	taurine transporter ATP-binding subunit; Provisional; Region: tauB; PRK11248
595495013402	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
595495013403	Walker A/P-loop; other site
595495013404	ATP binding site [chemical binding]; other site
595495013405	Q-loop/lid; other site
595495013406	ABC transporter signature motif; other site
595495013407	Walker B; other site
595495013408	D-loop; other site
595495013409	H-loop/switch region; other site
595495013410	ABC-type taurine transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: TauA; COG4521
595495013411	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
595495013412	substrate binding pocket [chemical binding]; other site
595495013413	membrane-bound complex binding site; other site
595495013414	hinge residues; other site
595495013415	Uncharacterized proteins, LmbE homologs [Function unknown]; Region: COG2120
595495013416	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
595495013417	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
595495013418	DXD motif; other site
595495013419	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
595495013420	putative trimer interface [polypeptide binding]; other site
595495013421	putative CoA binding site [chemical binding]; other site
595495013422	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
595495013423	putative metal binding site [ion binding]; other site
595495013424	putative homodimer interface [polypeptide binding]; other site
595495013425	putative homotetramer interface [polypeptide binding]; other site
595495013426	putative homodimer-homodimer interface [polypeptide binding]; other site
595495013427	putative allosteric switch controlling residues; other site
595495013428	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
595495013429	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
595495013430	substrate binding site [chemical binding]; other site
595495013431	catalytic Zn binding site [ion binding]; other site
595495013432	NAD binding site [chemical binding]; other site
595495013433	structural Zn binding site [ion binding]; other site
595495013434	dimer interface [polypeptide binding]; other site
595495013435	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
595495013436	S-formylglutathione hydrolase; Region: PLN02442
595495013437	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
595495013438	putative 3-hydroxyphenylpropionic transporter MhpT; Provisional; Region: PRK11551
595495013439	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495013440	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495013441	4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated; Region: PRK08195
595495013442	4-hydroxy-2-oxovalerate aldolase, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_HOA; cd07943
595495013443	active site
595495013444	catalytic residues [active]
595495013445	metal binding site [ion binding]; metal-binding site
595495013446	DmpG-like communication domain; Region: DmpG_comm; pfam07836
595495013447	acetaldehyde dehydrogenase; Validated; Region: PRK08300
595495013448	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
595495013449	Prokaryotic acetaldehyde dehydrogenase, dimerisation; Region: AcetDehyd-dimer; pfam09290
595495013450	2-keto-4-pentenoate hydratase; Provisional; Region: mhpD; PRK11342
595495013451	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; Region: biphenyl_bphD; TIGR03343
595495013452	Subunit B of the Class III Extradiol ring-cleavage dioxygenase, 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB), which catalyzes the oxidization and subsequent ring-opening of 2,3-dihydroxyphenylpropionate; Region: MhpB_like; cd07365
595495013453	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
595495013454	putative active site [active]
595495013455	Fe(II) binding site [ion binding]; other site
595495013456	putative dimer interface [polypeptide binding]; other site
595495013457	putative tetramer interface [polypeptide binding]; other site
595495013458	3-(3-hydroxyphenyl)propionate hydroxylase; Validated; Region: mhpA; PRK06183
595495013459	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
595495013460	DNA-binding transcriptional activator MhpR; Provisional; Region: PRK09834
595495013461	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
595495013462	Bacterial transcriptional regulator; Region: IclR; pfam01614
595495013463	lac repressor; Reviewed; Region: lacI; PRK09526
595495013464	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
595495013465	DNA binding site [nucleotide binding]
595495013466	domain linker motif; other site
595495013467	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
595495013468	ligand binding site [chemical binding]; other site
595495013469	dimerization interface (open form) [polypeptide binding]; other site
595495013470	dimerization interface (closed form) [polypeptide binding]; other site
595495013471	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
595495013472	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
595495013473	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
595495013474	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
595495013475	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
595495013476	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
595495013477	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495013478	putative substrate translocation pore; other site
595495013479	galactoside O-acetyltransferase; Reviewed; Region: lacA; PRK09527
595495013480	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
595495013481	active site
595495013482	substrate binding site [chemical binding]; other site
595495013483	trimer interface [polypeptide binding]; other site
595495013484	CoA binding site [chemical binding]; other site
595495013485	putative cyanate transporter; Provisional; Region: cynX; PRK09705
595495013486	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495013487	Cyanate lyase [Inorganic ion transport and metabolism]; Region: CynS; COG1513
595495013488	Cyanase C-terminal domain. Cyanase (Cyanate lyase) is responsible for the hydrolysis of cyanate.  It catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. This allows organisms that possess the enzyme to overcome the...; Region: Cyanase_C; cd00559
595495013489	oligomer interface [polypeptide binding]; other site
595495013490	active site
595495013491	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
595495013492	active site clefts [active]
595495013493	zinc binding site [ion binding]; other site
595495013494	dimer interface [polypeptide binding]; other site
595495013495	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
595495013496	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495013497	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator CynR, contains the type 2 periplasmic binding fold; Region: PBP2_CynR; cd08425
595495013498	dimerization interface [polypeptide binding]; other site
595495013499	cytosine deaminase; Provisional; Region: PRK09230
595495013500	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
595495013501	active site
595495013502	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
595495013503	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
595495013504	Na binding site [ion binding]; other site
595495013505	putative substrate binding site [chemical binding]; other site
595495013506	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
595495013507	Propionyl-CoA synthetase (PrpE); Region: PrpE; cd05967
595495013508	acyl-activating enzyme (AAE) consensus motif; other site
595495013509	putative AMP binding site [chemical binding]; other site
595495013510	putative active site [active]
595495013511	putative CoA binding site [chemical binding]; other site
595495013512	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
595495013513	2-methylcitrate dehydratase; Region: prpD; TIGR02330
595495013514	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
595495013515	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
595495013516	dimer interface [polypeptide binding]; other site
595495013517	active site
595495013518	citrylCoA binding site [chemical binding]; other site
595495013519	oxalacetate/citrate binding site [chemical binding]; other site
595495013520	coenzyme A binding site [chemical binding]; other site
595495013521	catalytic triad [active]
595495013522	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
595495013523	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
595495013524	tetramer interface [polypeptide binding]; other site
595495013525	active site
595495013526	Mg2+/Mn2+ binding site [ion binding]; other site
595495013527	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
595495013528	Propionate catabolism activator; Region: PrpR_N; pfam06506
595495013529	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495013530	Walker A motif; other site
595495013531	ATP binding site [chemical binding]; other site
595495013532	Walker B motif; other site
595495013533	arginine finger; other site
595495013534	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
595495013535	hypothetical protein; Provisional; Region: PRK09929
595495013536	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
595495013537	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
595495013538	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
595495013539	putative NAD(P) binding site [chemical binding]; other site
595495013540	putative substrate binding site [chemical binding]; other site
595495013541	catalytic Zn binding site [ion binding]; other site
595495013542	structural Zn binding site [ion binding]; other site
595495013543	dimer interface [polypeptide binding]; other site
595495013544	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
595495013545	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
595495013546	TM-ABC transporter signature motif; other site
595495013547	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
595495013548	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
595495013549	TM-ABC transporter signature motif; other site
595495013550	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
595495013551	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
595495013552	Walker A/P-loop; other site
595495013553	ATP binding site [chemical binding]; other site
595495013554	Q-loop/lid; other site
595495013555	ABC transporter signature motif; other site
595495013556	Walker B; other site
595495013557	D-loop; other site
595495013558	H-loop/switch region; other site
595495013559	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
595495013560	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
595495013561	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
595495013562	ligand binding site [chemical binding]; other site
595495013563	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
595495013564	putative deaminase; Validated; Region: PRK06846
595495013565	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
595495013566	active site
595495013567	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
595495013568	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
595495013569	putative substrate binding site [chemical binding]; other site
595495013570	nucleotide binding site [chemical binding]; other site
595495013571	nucleotide binding site [chemical binding]; other site
595495013572	homodimer interface [polypeptide binding]; other site
595495013573	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
595495013574	Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Region: SucD; COG0074
595495013575	CoA binding domain; Region: CoA_binding; pfam02629
595495013576	CoA-ligase; Region: Ligase_CoA; pfam00549
595495013577	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
595495013578	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
595495013579	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
595495013580	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
595495013581	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
595495013582	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
595495013583	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495013584	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
595495013585	dimerization interface [polypeptide binding]; other site
595495013586	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
595495013587	DNA binding residues [nucleotide binding]
595495013588	dimerization interface [polypeptide binding]; other site
595495013589	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
595495013590	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
595495013591	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
595495013592	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
595495013593	Autotransporter beta-domain; Region: Autotransporter; pfam03797
595495013594	choline transport protein BetT; Provisional; Region: PRK09928
595495013595	transcriptional regulator BetI; Validated; Region: PRK00767
595495013596	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
595495013597	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
595495013598	betaine aldehyde dehydrogenase; Provisional; Region: PRK13252
595495013599	NAD+-dependent 4-trimethylaminobutyraldehyde dehydrogenase, ALDH family 9A1; Region: ALDH_F9_TMBADH; cd07090
595495013600	tetrameric interface [polypeptide binding]; other site
595495013601	NAD binding site [chemical binding]; other site
595495013602	catalytic residues [active]
595495013603	choline dehydrogenase; Validated; Region: PRK02106
595495013604	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
595495013605	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
595495013606	Uncharacterized conserved protein [Function unknown]; Region: COG1556
595495013607	iron-sulfur cluster-binding protein; Region: TIGR00273
595495013608	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
595495013609	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
595495013610	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
595495013611	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
595495013612	Cysteine-rich domain; Region: CCG; pfam02754
595495013613	Cysteine-rich domain; Region: CCG; pfam02754
595495013614	Cupin; Region: Cupin_6; pfam12852
595495013615	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
595495013616	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495013617	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
595495013618	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
595495013619	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
595495013620	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
595495013621	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
595495013622	Predicted membrane protein [Function unknown]; Region: COG3059
595495013623	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
595495013624	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
595495013625	active site
595495013626	catalytic tetrad [active]
595495013627	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
595495013628	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495013629	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
595495013630	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
595495013631	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
595495013632	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
595495013633	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
595495013634	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
595495013635	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
595495013636	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
595495013637	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
595495013638	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
595495013639	DNA binding residues [nucleotide binding]
595495013640	putative fimbrial protein TcfA; Provisional; Region: PRK15308
595495013641	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
595495013642	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
595495013643	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
595495013644	Protein of unknown function (DUF1440); Region: DUF1440; cl01380
595495013645	aldehyde oxidoreductase 2Fe-2S subunit; Provisional; Region: PRK11433
595495013646	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
595495013647	catalytic loop [active]
595495013648	iron binding site [ion binding]; other site
595495013649	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
595495013650	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
595495013651	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; smart01092
595495013652	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
595495013653	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
595495013654	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
595495013655	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
595495013656	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
595495013657	XdhC Rossmann domain; Region: XdhC_C; pfam13478
595495013658	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
595495013659	Transcriptional regulator [Transcription]; Region: LysR; COG0583
595495013660	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
595495013661	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
595495013662	putative catalytic cysteine [active]
595495013663	gamma-glutamyl kinase; Provisional; Region: PRK05429
595495013664	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
595495013665	nucleotide binding site [chemical binding]; other site
595495013666	homotetrameric interface [polypeptide binding]; other site
595495013667	putative phosphate binding site [ion binding]; other site
595495013668	putative allosteric binding site; other site
595495013669	PUA domain; Region: PUA; pfam01472
595495013670	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
595495013671	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
595495013672	trimer interface [polypeptide binding]; other site
595495013673	eyelet of channel; other site
595495013674	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
595495013675	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
595495013676	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
595495013677	active site
595495013678	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
595495013679	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
595495013680	metal binding site [ion binding]; metal-binding site
595495013681	dimer interface [polypeptide binding]; other site
595495013682	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
595495013683	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
595495013684	hypothetical protein; Reviewed; Region: PRK09588
595495013685	release factor H-coupled RctB family protein; Region: release_rtcB; TIGR03073
595495013686	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
595495013687	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
595495013688	Coenzyme A binding pocket [chemical binding]; other site
595495013689	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
595495013690	active site
595495013691	DNA polymerase IV; Validated; Region: PRK02406
595495013692	DNA binding site [nucleotide binding]
595495013693	hypothetical protein; Validated; Region: PRK06778
595495013694	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
595495013695	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
595495013696	ligand binding site [chemical binding]; other site
595495013697	flagellar motor protein MotA; Provisional; Region: PRK12482
595495013698	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
595495013699	flagellar biosynthesis sigma factor; Provisional; Region: PRK12427
595495013700	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
595495013701	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
595495013702	DNA binding residues [nucleotide binding]
595495013703	Flagellar basal body-associated protein FliL; Region: FliL; pfam03748
595495013704	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
595495013705	adenylate kinase; Region: PLN02674
595495013706	Flagellar protein FliS; Region: FliS; cl00654
595495013707	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
595495013708	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
595495013709	flagellin; Reviewed; Region: PRK08869
595495013710	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
595495013711	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
595495013712	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495013713	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
595495013714	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
595495013715	DNA binding site [nucleotide binding]
595495013716	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK07192
595495013717	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
595495013718	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK07191
595495013719	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
595495013720	Rod binding protein; Region: Rod-binding; cl01626
595495013721	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
595495013722	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
595495013723	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK12407
595495013724	Flagellar L-ring protein; Region: FlgH; pfam02107
595495013725	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
595495013726	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
595495013727	flagellar basal body rod protein FlgF; Reviewed; Region: flgF; PRK12640
595495013728	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
595495013729	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
595495013730	flagellar hook protein FlgE; Validated; Region: flgE; PRK06803
595495013731	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
595495013732	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
595495013733	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
595495013734	Flagellar hook capping protein [Cell motility and secretion]; Region: FlgD; COG1843
595495013735	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
595495013736	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
595495013737	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK06802
595495013738	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
595495013739	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
595495013740	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK12685
595495013741	SAF-like; Region: SAF_2; pfam13144
595495013742	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
595495013743	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
595495013744	Anti-sigma-28 factor, FlgM; Region: FlgM; pfam04316
595495013745	FlgN protein; Region: FlgN; pfam05130
595495013746	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
595495013747	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
595495013748	active site
595495013749	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
595495013750	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
595495013751	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
595495013752	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
595495013753	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
595495013754	Mu DNA binding, I gamma subdomain; Region: HTH_Tnp_Mu_2; pfam09039
595495013755	Bacteriophage Mu transposase; Region: DDE_2; pfam02914
595495013756	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
595495013757	poxB regulator PoxA; Provisional; Region: PRK09350
595495013758	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
595495013759	motif 1; other site
595495013760	dimer interface [polypeptide binding]; other site
595495013761	active site
595495013762	motif 2; other site
595495013763	motif 3; other site
595495013764	inner membrane transporter YjeM; Provisional; Region: PRK15238
595495013765	Protein of unknown function (DUF2645); Region: DUF2645; pfam10840
595495013766	putative mechanosensitive channel protein; Provisional; Region: PRK10929
595495013767	linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated...; Region: H15; cl00073
595495013768	DNA-binding site [nucleotide binding]; DNA binding site
595495013769	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
595495013770	Mechanosensitive ion channel; Region: MS_channel; pfam00924
595495013771	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
595495013772	GTPase RsgA; Reviewed; Region: PRK12288
595495013773	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
595495013774	RNA binding site [nucleotide binding]; other site
595495013775	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
595495013776	GTPase/Zn-binding domain interface [polypeptide binding]; other site
595495013777	GTP/Mg2+ binding site [chemical binding]; other site
595495013778	G4 box; other site
595495013779	G5 box; other site
595495013780	G1 box; other site
595495013781	Switch I region; other site
595495013782	G2 box; other site
595495013783	G3 box; other site
595495013784	Switch II region; other site
595495013785	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
595495013786	catalytic site [active]
595495013787	putative active site [active]
595495013788	putative substrate binding site [chemical binding]; other site
595495013789	dimer interface [polypeptide binding]; other site
595495013790	epoxyqueuosine reductase; Region: TIGR00276
595495013791	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
595495013792	putative carbohydrate kinase; Provisional; Region: PRK10565
595495013793	yjeF N-terminal region; Region: yjeF_nterm; TIGR00197
595495013794	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
595495013795	putative substrate binding site [chemical binding]; other site
595495013796	putative ATP binding site [chemical binding]; other site
595495013797	ADP-binding protein; Provisional; Region: PRK10646
595495013798	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
595495013799	AMIN domain; Region: AMIN; pfam11741
595495013800	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
595495013801	active site
595495013802	metal binding site [ion binding]; metal-binding site
595495013803	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
595495013804	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495013805	ATP binding site [chemical binding]; other site
595495013806	Mg2+ binding site [ion binding]; other site
595495013807	G-X-G motif; other site
595495013808	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
595495013809	ATP binding site [chemical binding]; other site
595495013810	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
595495013811	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
595495013812	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
595495013813	bacterial Hfq-like; Region: Hfq; cd01716
595495013814	hexamer interface [polypeptide binding]; other site
595495013815	Sm1 motif; other site
595495013816	RNA binding site [nucleotide binding]; other site
595495013817	Sm2 motif; other site
595495013818	GTPase HflX; Provisional; Region: PRK11058
595495013819	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
595495013820	HflX GTPase family; Region: HflX; cd01878
595495013821	G1 box; other site
595495013822	GTP/Mg2+ binding site [chemical binding]; other site
595495013823	Switch I region; other site
595495013824	G2 box; other site
595495013825	G3 box; other site
595495013826	Switch II region; other site
595495013827	G4 box; other site
595495013828	G5 box; other site
595495013829	FtsH protease regulator HflK; Provisional; Region: PRK10930
595495013830	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
595495013831	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
595495013832	FtsH protease regulator HflC; Provisional; Region: PRK11029
595495013833	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
595495013834	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
595495013835	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
595495013836	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
595495013837	GDP-binding site [chemical binding]; other site
595495013838	ACT binding site; other site
595495013839	IMP binding site; other site
595495013840	Predicted transcriptional regulator [Transcription]; Region: COG1959
595495013841	transcriptional repressor NsrR; Provisional; Region: PRK11014
595495013842	exoribonuclease R; Provisional; Region: PRK11642
595495013843	Ribonuclease R winged-helix domain; Region: HTH_12; pfam08461
595495013844	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
595495013845	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
595495013846	RNB domain; Region: RNB; pfam00773
595495013847	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
595495013848	RNA binding site [nucleotide binding]; other site
595495013849	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
595495013850	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
595495013851	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
595495013852	Uncharacterized protein conserved in bacteria (DUF2170); Region: DUF2170; cl01551
595495013853	PspA/IM30 family; Region: PspA_IM30; pfam04012
595495013854	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
595495013855	Predicted membrane protein [Function unknown]; Region: COG3766
595495013856	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
595495013857	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
595495013858	Predicted integral membrane protein [Function unknown]; Region: COG5463
595495013859	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
595495013860	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
595495013861	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
595495013862	FAD binding site [chemical binding]; other site
595495013863	substrate binding site [chemical binding]; other site
595495013864	catalytic residues [active]
595495013865	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
595495013866	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
595495013867	esterase; Provisional; Region: PRK10566
595495013868	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
595495013869	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
595495013870	transcriptional repressor UlaR; Provisional; Region: PRK13509
595495013871	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
595495013872	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
595495013873	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
595495013874	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
595495013875	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
595495013876	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
595495013877	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
595495013878	active site
595495013879	P-loop; other site
595495013880	phosphorylation site [posttranslational modification]
595495013881	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
595495013882	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
595495013883	active site
595495013884	phosphorylation site [posttranslational modification]
595495013885	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
595495013886	active site
595495013887	dimer interface [polypeptide binding]; other site
595495013888	magnesium binding site [ion binding]; other site
595495013889	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
595495013890	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
595495013891	AP (apurinic/apyrimidinic) site pocket; other site
595495013892	DNA interaction; other site
595495013893	Metal-binding active site; metal-binding site
595495013894	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
595495013895	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
595495013896	intersubunit interface [polypeptide binding]; other site
595495013897	active site
595495013898	Zn2+ binding site [ion binding]; other site
595495013899	Protein of unknown function (DUF1440); Region: DUF1440; pfam07274
595495013900	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
595495013901	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
595495013902	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
595495013903	dimer interface [polypeptide binding]; other site
595495013904	ssDNA binding site [nucleotide binding]; other site
595495013905	tetramer (dimer of dimers) interface [polypeptide binding]; other site
595495013906	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
595495013907	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
595495013908	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
595495013909	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
595495013910	Protein of unknown function (DUF2686); Region: DUF2686; pfam10887
595495013911	Transposase IS200 like; Region: Y1_Tnp; pfam01797
595495013912	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
595495013913	Probable transposase; Region: OrfB_IS605; pfam01385
595495013914	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
595495013915	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
595495013916	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
595495013917	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
595495013918	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
595495013919	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
595495013920	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
595495013921	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
595495013922	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
595495013923	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
595495013924	Hemerythrin-like domain; Region: Hr-like; cd12108
595495013925	Fe binding site [ion binding]; other site
595495013926	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
595495013927	EamA-like transporter family; Region: EamA; pfam00892
595495013928	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
595495013929	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
595495013930	NADP binding site [chemical binding]; other site
595495013931	Predicted transcriptional regulators [Transcription]; Region: COG1733
595495013932	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
595495013933	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
595495013934	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
595495013935	active site
595495013936	metal binding site [ion binding]; metal-binding site
595495013937	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
595495013938	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
595495013939	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
595495013940	active site
595495013941	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
595495013942	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
595495013943	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
595495013944	Domain of unknown function DUF21; Region: DUF21; pfam01595
595495013945	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
595495013946	Transporter associated domain; Region: CorC_HlyC; smart01091
595495013947	methionine sulfoxide reductase A; Provisional; Region: PRK00058
595495013948	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
595495013949	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
595495013950	Surface antigen; Region: Bac_surface_Ag; pfam01103
595495013951	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
595495013952	Family of unknown function (DUF490); Region: DUF490; pfam04357
595495013953	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
595495013954	putative active site pocket [active]
595495013955	dimerization interface [polypeptide binding]; other site
595495013956	putative catalytic residue [active]
595495013957	antitoxin ChpS; Provisional; Region: PRK11347
595495013958	toxin ChpB; Provisional; Region: PRK09812
595495013959	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
595495013960	dimer interface [polypeptide binding]; other site
595495013961	substrate binding site [chemical binding]; other site
595495013962	metal binding sites [ion binding]; metal-binding site
595495013963	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
595495013964	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
595495013965	putative ligand binding site [chemical binding]; other site
595495013966	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
595495013967	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
595495013968	Walker A/P-loop; other site
595495013969	ATP binding site [chemical binding]; other site
595495013970	Q-loop/lid; other site
595495013971	ABC transporter signature motif; other site
595495013972	Walker B; other site
595495013973	D-loop; other site
595495013974	H-loop/switch region; other site
595495013975	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
595495013976	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
595495013977	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
595495013978	TM-ABC transporter signature motif; other site
595495013979	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
595495013980	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
595495013981	TM-ABC transporter signature motif; other site
595495013982	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
595495013983	AMP binding site [chemical binding]; other site
595495013984	metal binding site [ion binding]; metal-binding site
595495013985	active site
595495013986	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
595495013987	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
595495013988	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
595495013989	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
595495013990	hypothetical protein; Provisional; Region: PRK05255
595495013991	peptidase PmbA; Provisional; Region: PRK11040
595495013992	Cytochrome b562; Region: Cytochrom_B562; cl01546
595495013993	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
595495013994	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495013995	FeS/SAM binding site; other site
595495013996	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
595495013997	ATP cone domain; Region: ATP-cone; pfam03477
595495013998	Class III ribonucleotide reductase; Region: RNR_III; cd01675
595495013999	effector binding site; other site
595495014000	active site
595495014001	Zn binding site [ion binding]; other site
595495014002	glycine loop; other site
595495014003	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
595495014004	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
595495014005	Ca binding site [ion binding]; other site
595495014006	active site
595495014007	catalytic site [active]
595495014008	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
595495014009	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
595495014010	active site turn [active]
595495014011	phosphorylation site [posttranslational modification]
595495014012	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
595495014013	trehalose repressor; Provisional; Region: treR; PRK09492
595495014014	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
595495014015	DNA binding site [nucleotide binding]
595495014016	domain linker motif; other site
595495014017	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
595495014018	dimerization interface [polypeptide binding]; other site
595495014019	ligand binding site [chemical binding]; other site
595495014020	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
595495014021	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
595495014022	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
595495014023	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
595495014024	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495014025	motif II; other site
595495014026	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
595495014027	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
595495014028	homotrimer interaction site [polypeptide binding]; other site
595495014029	putative active site [active]
595495014030	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
595495014031	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
595495014032	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
595495014033	aspartate carbamoyltransferase; Region: asp_carb_tr; TIGR00670
595495014034	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
595495014035	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
595495014036	PyrBI operon leader peptide; Region: PyrBI_leader; pfam08052
595495014037	YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198
595495014038	homotrimer interaction site [polypeptide binding]; other site
595495014039	putative active site [active]
595495014040	oxidoreductase; Provisional; Region: PRK12742
595495014041	classical (c) SDRs; Region: SDR_c; cd05233
595495014042	NAD(P) binding site [chemical binding]; other site
595495014043	active site
595495014044	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
595495014045	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
595495014046	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
595495014047	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
595495014048	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
595495014049	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
595495014050	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
595495014051	RNase E inhibitor protein; Provisional; Region: PRK11191
595495014052	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
595495014053	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
595495014054	Coenzyme A binding pocket [chemical binding]; other site
595495014055	Predicted membrane protein [Function unknown]; Region: COG4269
595495014056	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
595495014057	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
595495014058	HIGH motif; other site
595495014059	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
595495014060	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
595495014061	active site
595495014062	KMSKS motif; other site
595495014063	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
595495014064	tRNA binding surface [nucleotide binding]; other site
595495014065	anticodon binding site; other site
595495014066	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
595495014067	DNA polymerase III subunit chi; Validated; Region: PRK05728
595495014068	multifunctional aminopeptidase A; Provisional; Region: PRK00913
595495014069	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
595495014070	interface (dimer of trimers) [polypeptide binding]; other site
595495014071	Substrate-binding/catalytic site; other site
595495014072	Zn-binding sites [ion binding]; other site
595495014073	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
595495014074	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
595495014075	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
595495014076	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
595495014077	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
595495014078	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
595495014079	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
595495014080	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
595495014081	DNA binding site [nucleotide binding]
595495014082	domain linker motif; other site
595495014083	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
595495014084	putative dimerization interface [polypeptide binding]; other site
595495014085	putative ligand binding site [chemical binding]; other site
595495014086	fructuronate transporter; Provisional; Region: PRK10034; cl15264
595495014087	gluconate transporter; Region: gntP; TIGR00791
595495014088	gluconate 5-dehydrogenase; Provisional; Region: PRK08085
595495014089	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
595495014090	NADP binding site [chemical binding]; other site
595495014091	homodimer interface [polypeptide binding]; other site
595495014092	active site
595495014093	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
595495014094	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
595495014095	putative NAD(P) binding site [chemical binding]; other site
595495014096	catalytic Zn binding site [ion binding]; other site
595495014097	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
595495014098	ATP-binding site [chemical binding]; other site
595495014099	Gluconate-6-phosphate binding site [chemical binding]; other site
595495014100	Shikimate kinase; Region: SKI; pfam01202
595495014101	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
595495014102	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
595495014103	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
595495014104	putative NAD(P) binding site [chemical binding]; other site
595495014105	putative substrate binding site [chemical binding]; other site
595495014106	catalytic Zn binding site [ion binding]; other site
595495014107	structural Zn binding site [ion binding]; other site
595495014108	dimer interface [polypeptide binding]; other site
595495014109	integrase; Provisional; Region: PRK09692
595495014110	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
595495014111	active site
595495014112	Int/Topo IB signature motif; other site
595495014113	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
595495014114	HNH endonuclease; Region: HNH_2; pfam13391
595495014115	5'-nucleotidase; Region: 5-nucleotidase; pfam06189
595495014116	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
595495014117	active site
595495014118	catalytic triad [active]
595495014119	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
595495014120	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
595495014121	HsdM N-terminal domain; Region: HsdM_N; pfam12161
595495014122	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
595495014123	Methyltransferase domain; Region: Methyltransf_26; pfam13659
595495014124	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
595495014125	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: HsdR; COG4096
595495014126	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
595495014127	ATP binding site [chemical binding]; other site
595495014128	putative Mg++ binding site [ion binding]; other site
595495014129	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
595495014130	Predicted transcriptional regulator [Transcription]; Region: COG2378
595495014131	WYL domain; Region: WYL; cl14852
595495014132	Predicted GTPase [General function prediction only]; Region: COG3596
595495014133	YfjP GTPase; Region: YfjP; cd11383
595495014134	G1 box; other site
595495014135	GTP/Mg2+ binding site [chemical binding]; other site
595495014136	Switch I region; other site
595495014137	G2 box; other site
595495014138	Switch II region; other site
595495014139	G3 box; other site
595495014140	G4 box; other site
595495014141	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
595495014142	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
595495014143	Domain of unknown function (DUF932); Region: DUF932; pfam06067
595495014144	hypothetical protein; Reviewed; Region: PRK00024
595495014145	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
595495014146	MPN+ (JAMM) motif; other site
595495014147	Zinc-binding site [ion binding]; other site
595495014148	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
595495014149	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
595495014150	Methyltransferase domain; Region: Methyltransf_27; pfam13708
595495014151	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
595495014152	integrase; Provisional; Region: PRK09692
595495014153	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
595495014154	active site
595495014155	Int/Topo IB signature motif; other site
595495014156	Protein kinase domain; Region: Pkinase; pfam00069
595495014157	Catalytic domain of Protein Kinases; Region: PKc; cd00180
595495014158	active site
595495014159	ATP binding site [chemical binding]; other site
595495014160	substrate binding site [chemical binding]; other site
595495014161	activation loop (A-loop); other site
595495014162	HerA helicase [Replication, recombination, and repair]; Region: COG0433
595495014163	Domain of unknown function DUF87; Region: DUF87; pfam01935
595495014164	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
595495014165	Methyltransferase domain; Region: Methyltransf_26; pfam13659
595495014166	McrBC 5-methylcytosine restriction system component; Region: McrBC; pfam10117
595495014167	AAA domain (dynein-related subfamily); Region: AAA_5; pfam07728
595495014168	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
595495014169	HNH endonuclease; Region: HNH_2; pfam13391
595495014170	Domain of unknown function (DUF303); Region: DUF303; pfam03629
595495014171	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
595495014172	Kelch motif; Region: Kelch_1; pfam01344
595495014173	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
595495014174	FimB and FimE and related proteins, DNA breaking-rejoining enzymes, integrase/recombinases, catalytic domain. This CD includes those proteins similar to E.coli FimE and FimB regulatory proteins and Proteus mirabilis MrpI; Region: INT_FimBE_C; cd01197
595495014175	Int/Topo IB signature motif; other site
595495014176	FimB and FimE and related proteins, DNA breaking-rejoining enzymes, integrase/recombinases, catalytic domain. This CD includes those proteins similar to E.coli FimE and FimB regulatory proteins and Proteus mirabilis MrpI; Region: INT_FimBE_C; cd01197
595495014177	Int/Topo IB signature motif; other site
595495014178	Fimbrial protein; Region: Fimbrial; cl01416
595495014179	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
595495014180	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
595495014181	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
595495014182	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
595495014183	outer membrane usher protein; Provisional; Region: PRK15193
595495014184	PapC N-terminal domain; Region: PapC_N; pfam13954
595495014185	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
595495014186	PapC C-terminal domain; Region: PapC_C; pfam13953
595495014187	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
595495014188	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
595495014189	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
595495014190	mannosyl binding site [chemical binding]; other site
595495014191	Fimbrial protein; Region: Fimbrial; pfam00419
595495014192	fructuronate transporter; Provisional; Region: PRK10034
595495014193	gluconate transporter; Region: gntP; TIGR00791
595495014194	mannonate dehydratase; Region: uxuA; TIGR00695
595495014195	mannonate dehydratase; Provisional; Region: PRK03906
595495014196	D-mannonate oxidoreductase; Provisional; Region: PRK15037
595495014197	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
595495014198	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
595495014199	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
595495014200	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
595495014201	DNA-binding site [nucleotide binding]; DNA binding site
595495014202	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
595495014203	Protein of unknown function (DUF2686); Region: DUF2686; pfam10887
595495014204	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
595495014205	cell density-dependent motility repressor; Provisional; Region: PRK10082
595495014206	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
595495014207	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
595495014208	Isoaspartyl dipeptidase hydrolyzes the beta-L-isoaspartyl linkages in dipeptides, as part of the degradative pathway to eliminate proteins with beta-L-isoaspartyl peptide bonds, bonds whereby the beta-group of an aspartate forms the peptide link with the...; Region: Isoaspartyl-dipeptidase; cd01308
595495014209	isoaspartyl dipeptidase IadA; Region: isoAsp_dipep; TIGR01975
595495014210	dimer interface [polypeptide binding]; other site
595495014211	active site
595495014212	hypothetical protein; Provisional; Region: PRK10519
595495014213	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
595495014214	Nucleoside recognition; Region: Gate; pfam07670
595495014215	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
595495014216	RNA 2'-phosphotransferase; Reviewed; Region: PRK00819
595495014217	Protein of unknown function (DUF1228); Region: DUF1228; pfam06779
595495014218	SdiA-regulated; Region: SdiA-regulated; pfam06977
595495014219	SdiA-regulated; Region: SdiA-regulated; cd09971
595495014220	putative active site [active]
595495014221	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
595495014222	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
595495014223	CoA-substrate-specific enzyme activase, putative; Region: CoA_E_activ; TIGR00241
595495014224	Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB [Amino acid transport and metabolism]; Region: HgdB; COG1775
595495014225	benzoyl-CoA reductase, subunit C; Region: benz_CoA_red_C; TIGR02263
595495014226	Predicted membrane protein [Function unknown]; Region: COG2733
595495014227	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
595495014228	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495014229	putative substrate translocation pore; other site
595495014230	putative transposase; Provisional; Region: PRK09857
595495014231	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
595495014232	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
595495014233	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
595495014234	DNA-binding site [nucleotide binding]; DNA binding site
595495014235	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
595495014236	pyridoxal 5'-phosphate binding site [chemical binding]; other site
595495014237	homodimer interface [polypeptide binding]; other site
595495014238	catalytic residue [active]
595495014239	Uncharacterized conserved small protein [Function unknown]; Region: COG5457
595495014240	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
595495014241	Penicillin amidase; Region: Penicil_amidase; pfam01804
595495014242	Penicillin G acylase (PGA) is the key enzyme in the industrial production of beta-lactam antibiotics. PGA hydrolyzes the side chain of penicillin G and related beta-lactam antibiotics releasing 6-amino penicillanic acid (6-APA), a building block in the...; Region: Ntn_PGA; cd03748
595495014243	active site
595495014244	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
595495014245	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
595495014246	P-loop, Walker A motif; other site
595495014247	Base recognition motif; other site
595495014248	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
595495014249	Uncharacterized small protein [Function unknown]; Region: COG2879
595495014250	carbon starvation protein A; Provisional; Region: PRK15015
595495014251	Carbon starvation protein CstA; Region: CstA; pfam02554
595495014252	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
595495014253	4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional; Region: hpaC; PRK15486
595495014254	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
595495014255	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
595495014256	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
595495014257	Cupin domain; Region: Cupin_2; pfam07883
595495014258	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495014259	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495014260	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
595495014261	putative substrate translocation pore; other site
595495014262	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
595495014263	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
595495014264	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
595495014265	putative substrate binding pocket [chemical binding]; other site
595495014266	trimer interface [polypeptide binding]; other site
595495014267	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
595495014268	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
595495014269	putative active site [active]
595495014270	putative metal binding site [ion binding]; other site
595495014271	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
595495014272	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
595495014273	NAD binding site [chemical binding]; other site
595495014274	catalytic residues [active]
595495014275	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional; Region: PRK15203
595495014276	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit; Region: HpaG-N-term; TIGR02305
595495014277	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
595495014278	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
595495014279	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
595495014280	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
595495014281	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
595495014282	dimer interface [polypeptide binding]; other site
595495014283	ligand binding site [chemical binding]; other site
595495014284	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
595495014285	dimerization interface [polypeptide binding]; other site
595495014286	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
595495014287	dimer interface [polypeptide binding]; other site
595495014288	putative CheW interface [polypeptide binding]; other site
595495014289	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
595495014290	D-galactonate transporter; Region: 2A0114; TIGR00893
595495014291	putative substrate translocation pore; other site
595495014292	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
595495014293	DNA-binding site [nucleotide binding]; DNA binding site
595495014294	Transcriptional regulators [Transcription]; Region: GntR; COG1802
595495014295	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
595495014296	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
595495014297	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
595495014298	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
595495014299	putative NAD(P) binding site [chemical binding]; other site
595495014300	catalytic Zn binding site [ion binding]; other site
595495014301	structural Zn binding site [ion binding]; other site
595495014302	phosphoglycerol transferase I; Provisional; Region: PRK03776
595495014303	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
595495014304	hypothetical protein; Provisional; Region: PRK11667
595495014305	DNA replication protein DnaC; Validated; Region: PRK07952
595495014306	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
595495014307	Walker A motif; other site
595495014308	ATP binding site [chemical binding]; other site
595495014309	Walker B motif; other site
595495014310	primosomal protein DnaI; Provisional; Region: PRK02854
595495014311	hypothetical protein; Provisional; Region: PRK09917
595495014312	Uncharacterized conserved protein [Function unknown]; Region: COG2966
595495014313	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
595495014314	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
595495014315	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
595495014316	DNA binding residues [nucleotide binding]
595495014317	dimerization interface [polypeptide binding]; other site
595495014318	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
595495014319	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
595495014320	DNA binding residues [nucleotide binding]
595495014321	dimerization interface [polypeptide binding]; other site
595495014322	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
595495014323	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
595495014324	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
595495014325	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
595495014326	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
595495014327	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
595495014328	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
595495014329	S-adenosylmethionine binding site [chemical binding]; other site
595495014330	DNA polymerase III, psi subunit [DNA replication, recombination, and repair]; Region: HolD; COG3050
595495014331	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
595495014332	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
595495014333	Coenzyme A binding pocket [chemical binding]; other site
595495014334	dUMP phosphatase; Provisional; Region: PRK09449
595495014335	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495014336	motif II; other site
595495014337	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
595495014338	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
595495014339	G1 box; other site
595495014340	putative GEF interaction site [polypeptide binding]; other site
595495014341	GTP/Mg2+ binding site [chemical binding]; other site
595495014342	Switch I region; other site
595495014343	G2 box; other site
595495014344	G3 box; other site
595495014345	Switch II region; other site
595495014346	G4 box; other site
595495014347	G5 box; other site
595495014348	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
595495014349	periplasmic protein; Provisional; Region: PRK10568
595495014350	BON domain; Region: BON; pfam04972
595495014351	BON domain; Region: BON; pfam04972
595495014352	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
595495014353	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
595495014354	active site
595495014355	nucleophile elbow; other site
595495014356	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
595495014357	active site
595495014358	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
595495014359	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
595495014360	FeS/SAM binding site; other site
595495014361	hypothetical protein; Provisional; Region: PRK10977
595495014362	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
595495014363	intersubunit interface [polypeptide binding]; other site
595495014364	active site
595495014365	catalytic residue [active]
595495014366	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
595495014367	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
595495014368	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
595495014369	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
595495014370	phosphopentomutase; Provisional; Region: PRK05362
595495014371	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
595495014372	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
595495014373	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
595495014374	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
595495014375	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
595495014376	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
595495014377	hypothetical protein; Provisional; Region: PRK11246
595495014378	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
595495014379	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
595495014380	motif II; other site
595495014381	DNA repair protein RadA; Region: sms; TIGR00416
595495014382	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
595495014383	Walker A motif/ATP binding site; other site
595495014384	ATP binding site [chemical binding]; other site
595495014385	Walker B motif; other site
595495014386	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
595495014387	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
595495014388	non-specific DNA binding site [nucleotide binding]; other site
595495014389	salt bridge; other site
595495014390	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
595495014391	sequence-specific DNA binding site [nucleotide binding]; other site
595495014392	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
595495014393	active site
595495014394	(T/H)XGH motif; other site
595495014395	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
595495014396	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
595495014397	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495014398	Walker A/P-loop; other site
595495014399	ATP binding site [chemical binding]; other site
595495014400	Q-loop/lid; other site
595495014401	ABC transporter signature motif; other site
595495014402	Walker B; other site
595495014403	D-loop; other site
595495014404	H-loop/switch region; other site
595495014405	ABC transporter; Region: ABC_tran_2; pfam12848
595495014406	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
595495014407	lytic murein transglycosylase; Provisional; Region: PRK11619
595495014408	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
595495014409	N-acetyl-D-glucosamine binding site [chemical binding]; other site
595495014410	catalytic residue [active]
595495014411	Trp operon repressor; Provisional; Region: PRK01381
595495014412	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
595495014413	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
595495014414	catalytic core [active]
595495014415	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
595495014416	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
595495014417	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
595495014418	hypothetical protein; Provisional; Region: PRK10756
595495014419	CreA protein; Region: CreA; pfam05981
595495014420	DNA-binding response regulator CreB; Provisional; Region: PRK11083
595495014421	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495014422	active site
595495014423	phosphorylation site [posttranslational modification]
595495014424	intermolecular recognition site; other site
595495014425	dimerization interface [polypeptide binding]; other site
595495014426	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
595495014427	DNA binding site [nucleotide binding]
595495014428	sensory histidine kinase CreC; Provisional; Region: PRK11100
595495014429	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
595495014430	dimerization interface [polypeptide binding]; other site
595495014431	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
595495014432	dimer interface [polypeptide binding]; other site
595495014433	phosphorylation site [posttranslational modification]
595495014434	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
595495014435	ATP binding site [chemical binding]; other site
595495014436	Mg2+ binding site [ion binding]; other site
595495014437	G-X-G motif; other site
595495014438	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
595495014439	two-component response regulator; Provisional; Region: PRK11173
595495014440	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
595495014441	active site
595495014442	phosphorylation site [posttranslational modification]
595495014443	intermolecular recognition site; other site
595495014444	dimerization interface [polypeptide binding]; other site
595495014445	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
595495014446	DNA binding site [nucleotide binding]
595495014447	putative RNA methyltransferase; Provisional; Region: PRK10433
595495014448	RNA methyltransferase, TrmH family, group 1; Region: rRNA_methyl_1; TIGR00050
595495014449	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
595495014450	Walker A/P-loop; other site
595495014451	ATP binding site [chemical binding]; other site
595495014452	AAA domain; Region: AAA_21; pfam13304
595495014453	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
595495014454	ATP binding site [chemical binding]; other site
595495014455	Q-loop/lid; other site
595495014456	ABC transporter signature motif; other site
595495014457	Walker B; other site
595495014458	D-loop; other site
595495014459	H-loop/switch region; other site
595495014460	Rop protein; Region: Rop; pfam01815
595495014461	Bacterial mobilisation protein (MobC); Region: MobC; pfam05713
595495014462	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
595495014463	MbeB-like, N-term conserved region; Region: MbeB_N; pfam04837
595495014464	MbeD/MobD like; Region: MbeD_MobD; pfam04899