-- dump date 20140619_082629 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 316385000001 SEQ_END SEQ_END NC_010473.1 4686137 4686137 DR NC_010473.1; contig end 4686137..4686137 Escherichia coli str. K-12 substr. DH10B YP_001728984.1 CDS thrL NC_010473.1 190 255 D involved in threonine biosynthesis; controls the expression of the thrLABC operon; thr operon leader peptide 190..255 Escherichia coli str. K-12 substr. DH10B 6058969 YP_001728985.1 CDS thrA NC_010473.1 337 2799 D multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 337..2799 Escherichia coli str. K-12 substr. DH10B 6058347 YP_001728986.1 CDS thrB NC_010473.1 2801 3733 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 2801..3733 Escherichia coli str. K-12 substr. DH10B 6058639 YP_001728987.1 CDS thrC NC_010473.1 3734 5020 D catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 3734..5020 Escherichia coli str. K-12 substr. DH10B 6062260 YP_001728988.1 CDS yaaX NC_010473.1 5234 5530 D hypothetical protein 5234..5530 Escherichia coli str. K-12 substr. DH10B 6061721 YP_001728989.1 CDS yaaA NC_010473.1 5683 6459 R hypothetical protein complement(5683..6459) Escherichia coli str. K-12 substr. DH10B 6061859 YP_001728990.1 CDS yaaJ NC_010473.1 6529 7959 R transporter complement(6529..7959) Escherichia coli str. K-12 substr. DH10B 6061809 YP_001728991.1 CDS talB NC_010473.1 8238 9191 D transaldolase B 8238..9191 Escherichia coli str. K-12 substr. DH10B 6061856 YP_001728992.1 CDS mogA NC_010473.1 9306 9893 D forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 9306..9893 Escherichia coli str. K-12 substr. DH10B 6061839 YP_001728993.1 CDS yaaH NC_010473.1 9928 10494 R hypothetical protein complement(9928..10494) Escherichia coli str. K-12 substr. DH10B 6060849 YP_001728994.1 CDS yaaW NC_010473.1 10643 11356 R hypothetical protein complement(10643..11356) Escherichia coli str. K-12 substr. DH10B 6060848 YP_001728995.1 CDS htgA NC_010473.1 10830 11315 D hypothetical protein 10830..11315 Escherichia coli str. K-12 substr. DH10B 6061775 YP_001728996.1 CDS yaaI NC_010473.1 11382 11786 R hypothetical protein complement(11382..11786) Escherichia coli str. K-12 substr. DH10B 6061719 YP_001728997.1 CDS dnaK NC_010473.1 12163 14079 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 12163..14079 Escherichia coli str. K-12 substr. DH10B 6060570 YP_001728998.1 CDS dnaJ NC_010473.1 14168 15298 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 14168..15298 Escherichia coli str. K-12 substr. DH10B 6060564 YP_001728999.1 CDS insL-1 NC_010473.1 15445 16557 D IS186/IS421 transposase 15445..16557 Escherichia coli str. K-12 substr. DH10B 6061805 YP_001729000.1 CDS mokC NC_010473.1 16751 16960 R regulatory protein for HokC, overlaps CDS of hokC complement(16751..16960) Escherichia coli str. K-12 substr. DH10B 6061760 YP_001729001.1 CDS hokC NC_010473.1 16751 16903 R toxic membrane protein, small complement(16751..16903) Escherichia coli str. K-12 substr. DH10B 6061702 YP_001729002.1 CDS nhaA NC_010473.1 17489 18655 D exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 17489..18655 Escherichia coli str. K-12 substr. DH10B 6059585 YP_001729003.1 CDS nhaR NC_010473.1 18715 19620 D Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 18715..19620 Escherichia coli str. K-12 substr. DH10B 6060870 YP_001729004.1 CDS insB-1 NC_010473.1 19811 20314 R IS1 transposase InsAB' complement(19811..20314) Escherichia coli str. K-12 substr. DH10B 6060829 YP_001729005.1 CDS insA-1 NC_010473.1 20233 20508 R IS1 repressor protein InsA complement(20233..20508) Escherichia coli str. K-12 substr. DH10B 6061774 YP_001729006.1 CDS rpsT NC_010473.1 20815 21078 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(20815..21078) Escherichia coli str. K-12 substr. DH10B 6061729 YP_001729007.1 CDS yaaY NC_010473.1 21181 21399 D hypothetical protein 21181..21399 Escherichia coli str. K-12 substr. DH10B 6061762 YP_001729008.1 CDS ribF NC_010473.1 21407 22348 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 21407..22348 Escherichia coli str. K-12 substr. DH10B 6060863 YP_001729009.1 CDS ileS NC_010473.1 22391 25207 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 22391..25207 Escherichia coli str. K-12 substr. DH10B 6060861 YP_001729010.1 CDS lspA NC_010473.1 25207 25701 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 25207..25701 Escherichia coli str. K-12 substr. DH10B 6060712 YP_001729011.1 CDS fkpB NC_010473.1 25826 26275 D FKBP-type peptidyl-prolyl cis-trans isomerase 25826..26275 Escherichia coli str. K-12 substr. DH10B 6061711 YP_001729012.1 CDS ispH NC_010473.1 26277 27227 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 26277..27227 Escherichia coli str. K-12 substr. DH10B 6061757 YP_001729013.1 CDS rihC NC_010473.1 27293 28207 D catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC 27293..28207 Escherichia coli str. K-12 substr. DH10B 6061670 YP_001729014.1 CDS dapB NC_010473.1 28374 29195 D catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 28374..29195 Escherichia coli str. K-12 substr. DH10B 6061749 YP_001729015.1 CDS carA NC_010473.1 29651 30799 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 29651..30799 Escherichia coli str. K-12 substr. DH10B 6061743 YP_001729016.1 CDS carB NC_010473.1 30817 34038 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 30817..34038 Escherichia coli str. K-12 substr. DH10B 6061731 YP_001729017.1 CDS caiF NC_010473.1 34300 34695 D regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 34300..34695 Escherichia coli str. K-12 substr. DH10B 6060689 YP_001729018.1 CDS caiE NC_010473.1 34781 35371 R involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE complement(34781..35371) Escherichia coli str. K-12 substr. DH10B 6060753 YP_001729019.2 CDS caiD NC_010473.1 35377 36162 R catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase complement(35377..36162) Escherichia coli str. K-12 substr. DH10B 6061640 YP_001729020.1 CDS caiC NC_010473.1 36271 37839 R putative crotonobetaine/carnitine-CoA ligase complement(36271..37839) Escherichia coli str. K-12 substr. DH10B 6061718 YP_001729021.1 CDS caiB NC_010473.1 37898 39115 R catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase complement(37898..39115) Escherichia coli str. K-12 substr. DH10B 6060847 YP_001729022.1 CDS caiA NC_010473.1 39244 40386 R catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase complement(39244..40386) Escherichia coli str. K-12 substr. DH10B 6061674 YP_001729023.1 CDS caiT NC_010473.1 40417 41931 R catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter complement(40417..41931) Escherichia coli str. K-12 substr. DH10B 6061707 YP_001729024.1 CDS fixA NC_010473.1 42403 43173 D required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; putative electron transfer flavoprotein FixA 42403..43173 Escherichia coli str. K-12 substr. DH10B 6060840 YP_001729025.1 CDS fixB NC_010473.1 43188 44129 D involved in electron transfer during carnitine metabolism; putative electron transfer flavoprotein FixB 43188..44129 Escherichia coli str. K-12 substr. DH10B 6061693 YP_001729026.1 CDS fixC NC_010473.1 44180 45466 D FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; putative oxidoreductase FixC 44180..45466 Escherichia coli str. K-12 substr. DH10B 6060832 YP_001729027.1 CDS fixX NC_010473.1 45463 45750 D 4Fe-4S ferredoxin 45463..45750 Escherichia coli str. K-12 substr. DH10B 6060834 YP_001729028.1 CDS yaaU NC_010473.1 45807 47138 D transporter 45807..47138 Escherichia coli str. K-12 substr. DH10B 6061685 YP_001729029.1 CDS kefF NC_010473.1 47246 47776 D Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 47246..47776 Escherichia coli str. K-12 substr. DH10B 6061681 YP_001729030.1 CDS kefC NC_010473.1 47769 49631 D transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 47769..49631 Escherichia coli str. K-12 substr. DH10B 6061581 YP_001729031.1 CDS folA NC_010473.1 49823 50302 D catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 49823..50302 Escherichia coli str. K-12 substr. DH10B 6061666 YP_001729032.1 CDS apaH NC_010473.1 50380 51222 R hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase complement(50380..51222) Escherichia coli str. K-12 substr. DH10B 6060780 YP_001729033.1 CDS apaG NC_010473.1 51229 51606 R protein associated with Co2+ and Mg2+ efflux; ApaG protein complement(51229..51606) Escherichia coli str. K-12 substr. DH10B 6060560 YP_001729034.1 CDS ksgA NC_010473.1 51609 52430 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(51609..52430) Escherichia coli str. K-12 substr. DH10B 6061655 YP_001729035.1 CDS pdxA NC_010473.1 52427 53416 R catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase complement(52427..53416) Escherichia coli str. K-12 substr. DH10B 6061608 YP_001729036.1 CDS surA NC_010473.1 53416 54702 R Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA complement(53416..54702) Escherichia coli str. K-12 substr. DH10B 6061611 YP_001729037.1 CDS imp NC_010473.1 54755 57109 R determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein complement(54755..57109) Escherichia coli str. K-12 substr. DH10B 6061599 YP_001729038.1 CDS djlA NC_010473.1 57364 58179 D functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 57364..58179 Escherichia coli str. K-12 substr. DH10B 6061527 YP_001729039.1 CDS rluA NC_010473.1 59687 60346 R catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A complement(59687..60346) Escherichia coli str. K-12 substr. DH10B 6058505 YP_001729040.1 CDS mraZ NC_010473.1 63738 64196 D MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 63738..64196 Escherichia coli str. K-12 substr. DH10B 6060357 YP_001729041.1 CDS mraW NC_010473.1 64198 65139 D contains two mutations: synonymous changes in codons 113 and 114; S-adenosyl-methyltransferase MraW 64198..65139 Escherichia coli str. K-12 substr. DH10B 6061555 YP_001729042.1 CDS ftsL NC_010473.1 65136 65501 D membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 65136..65501 Escherichia coli str. K-12 substr. DH10B 6060757 YP_001729043.1 CDS ftsI NC_010473.1 65517 67283 D contains eleven mutations: synonymous changes in codons 164, 168, 170, 179, 228, 250, 305, 314, 425, 466, and 477; transpeptidase involved in septal peptidoglycan synthesis (penicillin-binding protein 3) 65517..67283 Escherichia coli str. K-12 substr. DH10B 6061496 YP_001729044.1 CDS murE NC_010473.1 67270 68757 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 67270..68757 Escherichia coli str. K-12 substr. DH10B 6061495 YP_001729045.1 CDS murF NC_010473.1 68754 70112 D UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 68754..70112 Escherichia coli str. K-12 substr. DH10B 6061602 YP_001729046.1 CDS mraY NC_010473.1 70106 71188 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 70106..71188 Escherichia coli str. K-12 substr. DH10B 6061592 YP_001729047.1 CDS murD NC_010473.1 71191 72507 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 71191..72507 Escherichia coli str. K-12 substr. DH10B 6061589 YP_001729048.1 CDS ftsW NC_010473.1 72507 73751 D integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 72507..73751 Escherichia coli str. K-12 substr. DH10B 6062336 YP_001729049.1 CDS murG NC_010473.1 73748 74815 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 73748..74815 Escherichia coli str. K-12 substr. DH10B 6061471 YP_001729050.1 CDS murC NC_010473.1 74869 76344 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 74869..76344 Escherichia coli str. K-12 substr. DH10B 6061468 YP_001729051.1 CDS ddl NC_010473.1 76337 77257 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 76337..77257 Escherichia coli str. K-12 substr. DH10B 6061511 YP_001729052.1 CDS ftsQ NC_010473.1 77259 78089 D involved in septum formation; cell division protein FtsQ 77259..78089 Escherichia coli str. K-12 substr. DH10B 6061565 YP_001729053.1 CDS ftsA NC_010473.1 78086 79348 D ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 78086..79348 Escherichia coli str. K-12 substr. DH10B 6061506 YP_001729054.1 CDS ftsZ NC_010473.1 79409 80560 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 79409..80560 Escherichia coli str. K-12 substr. DH10B 6061490 YP_001729055.1 CDS lpxC NC_010473.1 80661 81578 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 80661..81578 Escherichia coli str. K-12 substr. DH10B 6061533 YP_001729056.1 CDS secM NC_010473.1 81809 82321 D secM translational pause allows for the initiation of secA translation; SecA regulator SecM 81809..82321 Escherichia coli str. K-12 substr. DH10B 6061485 YP_001729057.1 CDS secA NC_010473.1 82383 85088 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 82383..85088 Escherichia coli str. K-12 substr. DH10B 6060734 YP_001729058.1 CDS mutT NC_010473.1 85148 85537 D nucleoside triphosphate pyrophosphohydrolase 85148..85537 Escherichia coli str. K-12 substr. DH10B 6061521 YP_001729059.1 CDS yacG NC_010473.1 85753 85950 R zinc-binding protein complement(85753..85950) Escherichia coli str. K-12 substr. DH10B 6061455 YP_001729060.1 CDS yacF NC_010473.1 85960 86703 R hypothetical protein complement(85960..86703) Escherichia coli str. K-12 substr. DH10B 6061452 YP_001729061.1 CDS coaE NC_010473.1 86703 87323 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(86703..87323) Escherichia coli str. K-12 substr. DH10B 6060659 YP_001729062.1 CDS guaC NC_010473.1 87548 88591 D catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 87548..88591 Escherichia coli str. K-12 substr. DH10B 6061504 YP_001729063.1 CDS hofC NC_010473.1 88626 89828 R type IV pilin biogenesis protein complement(88626..89828) Escherichia coli str. K-12 substr. DH10B 6061353 YP_001729064.1 CDS hofB NC_010473.1 89818 91203 R hypothetical protein complement(89818..91203) Escherichia coli str. K-12 substr. DH10B 6061494 YP_001729065.1 CDS ppdD NC_010473.1 91213 91653 R putative major pilin subunit complement(91213..91653) Escherichia coli str. K-12 substr. DH10B 6062314 YP_001729066.1 CDS nadC NC_010473.1 91856 92749 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase complement(91856..92749) Escherichia coli str. K-12 substr. DH10B 6061483 YP_001729067.1 CDS ampD NC_010473.1 92837 93388 D N-acetyl-anhydromuranmyl-L-alanine amidase 92837..93388 Escherichia coli str. K-12 substr. DH10B 6061477 YP_001729068.1 CDS ampE NC_010473.1 93385 94239 D involved in regulation of beta-lactamase; putative signaling protein; regulatory protein AmpE 93385..94239 Escherichia coli str. K-12 substr. DH10B 6061475 YP_001729069.1 CDS aroP NC_010473.1 94282 95655 R aromatic amino acid transporter complement(94282..95655) Escherichia coli str. K-12 substr. DH10B 6061459 YP_001729070.1 CDS pdhR NC_010473.1 96196 96960 D activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 96196..96960 Escherichia coli str. K-12 substr. DH10B 6060779 YP_001729071.1 CDS aceE NC_010473.1 97121 99784 D E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 97121..99784 Escherichia coli str. K-12 substr. DH10B 6060775 YP_001729072.1 CDS aceF NC_010473.1 99799 101691 D E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 99799..101691 Escherichia coli str. K-12 substr. DH10B 6061449 YP_001729073.1 CDS lpd NC_010473.1 102016 103440 D E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 102016..103440 Escherichia coli str. K-12 substr. DH10B 6061443 YP_001729074.1 CDS yacH NC_010473.1 103511 105364 R hypothetical protein complement(103511..105364) Escherichia coli str. K-12 substr. DH10B 6061405 YP_001729075.1 CDS acnB NC_010473.1 105719 108316 D catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 105719..108316 Escherichia coli str. K-12 substr. DH10B 6061409 YP_001729076.1 CDS yacL NC_010473.1 108492 108854 D hypothetical protein 108492..108854 Escherichia coli str. K-12 substr. DH10B 6061436 YP_001729077.1 CDS speD NC_010473.1 108892 109686 R S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase complement(108892..109686) Escherichia coli str. K-12 substr. DH10B 6062345 YP_001729078.1 CDS speE NC_010473.1 109702 110568 R catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase complement(109702..110568) Escherichia coli str. K-12 substr. DH10B 6061294 YP_001729079.1 CDS yacC NC_010473.1 110674 111021 R hypothetical protein complement(110674..111021) Escherichia coli str. K-12 substr. DH10B 6060630 YP_001729080.1 CDS cueO NC_010473.1 111187 112737 D laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 111187..112737 Escherichia coli str. K-12 substr. DH10B 6060624 YP_001729081.1 CDS gcd NC_010473.1 112939 115329 R glucose dehydrogenase complement(112939..115329) Escherichia coli str. K-12 substr. DH10B 6060544 YP_001729082.1 CDS hpt NC_010473.1 115535 116071 D hypoxanthine phosphoribosyltransferase 115535..116071 Escherichia coli str. K-12 substr. DH10B 6060535 YP_001729083.1 CDS can NC_010473.1 116112 116774 R catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase complement(116112..116774) Escherichia coli str. K-12 substr. DH10B 6061219 YP_001729084.1 CDS yadG NC_010473.1 116883 117809 D ABC transporter ATP-binding protein 116883..117809 Escherichia coli str. K-12 substr. DH10B 6060761 YP_001729085.1 CDS yadH NC_010473.1 117806 118576 D ABC transporter membrane protein 117806..118576 Escherichia coli str. K-12 substr. DH10B 6060762 YP_001729086.1 CDS yadI NC_010473.1 118681 119121 D PTS enzyme IIA 118681..119121 Escherichia coli str. K-12 substr. DH10B 6061403 YP_001729087.1 CDS yadE NC_010473.1 119185 120414 D polysaccharide deacetylase lipoprotein 119185..120414 Escherichia coli str. K-12 substr. DH10B 6061401 YP_001729088.1 CDS panD NC_010473.1 120418 120798 R Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase complement(120418..120798) Escherichia coli str. K-12 substr. DH10B 6061400 YP_001729089.1 CDS yadD NC_010473.1 121072 121974 D transposase 121072..121974 Escherichia coli str. K-12 substr. DH10B 6061394 YP_001729090.1 CDS panC NC_010473.1 122048 122899 R catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase complement(122048..122899) Escherichia coli str. K-12 substr. DH10B 6061395 YP_001729091.1 CDS panB NC_010473.1 122911 123705 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(122911..123705) Escherichia coli str. K-12 substr. DH10B 6061341 YP_001729092.1 CDS yadC NC_010473.1 123819 125057 R putative fimbrial-like adhesin protein complement(123819..125057) Escherichia coli str. K-12 substr. DH10B 6062319 YP_001729093.1 CDS yadK NC_010473.1 125107 125703 R fimbrial-like adhesin protein complement(125107..125703) Escherichia coli str. K-12 substr. DH10B 6061375 YP_001729094.1 CDS yadL NC_010473.1 125730 126335 R fimbrial-like adhesin protein complement(125730..126335) Escherichia coli str. K-12 substr. DH10B 6060744 YP_001729095.1 CDS yadM NC_010473.1 126347 126916 R fimbrial-like adhesin protein complement(126347..126916) Escherichia coli str. K-12 substr. DH10B 6061374 YP_001729096.1 CDS htrE NC_010473.1 126933 129530 R similar to the fimbrial usher protein PapC; putative outer membrane usher protein complement(126933..129530) Escherichia coli str. K-12 substr. DH10B 6061364 YP_001729097.1 CDS ecpD NC_010473.1 129565 130305 R putative chaperone protein EcpD complement(129565..130305) Escherichia coli str. K-12 substr. DH10B 6061266 YP_001729098.1 CDS yadN NC_010473.1 130403 130987 R fimbrial-like adhesin protein complement(130403..130987) Escherichia coli str. K-12 substr. DH10B 6060575 YP_001729099.1 CDS folK NC_010473.1 131357 131836 R catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase complement(131357..131836) Escherichia coli str. K-12 substr. DH10B 6060572 YP_001729100.1 CDS pcnB NC_010473.1 131833 133230 R Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase I complement(131833..133230) Escherichia coli str. K-12 substr. DH10B 6061204 YP_001729101.1 CDS yadB NC_010473.1 133290 134216 R this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase complement(133290..134216) Escherichia coli str. K-12 substr. DH10B 6061205 YP_001729102.1 CDS dksA NC_010473.1 134253 134708 R RNA polymerase-binding transcription factor complement(134253..134708) Escherichia coli str. K-12 substr. DH10B 6061347 YP_001729103.1 CDS sfsA NC_010473.1 134886 135590 R Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A complement(134886..135590) Escherichia coli str. K-12 substr. DH10B 6062338 YP_001729104.1 CDS ligT NC_010473.1 135605 136135 R 2'-5' RNA ligase complement(135605..136135) Escherichia coli str. K-12 substr. DH10B 6061343 YP_001729105.1 CDS hrpB NC_010473.1 136209 138638 D similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 136209..138638 Escherichia coli str. K-12 substr. DH10B 6061344 YP_001729106.1 CDS mrcB NC_010473.1 138834 141368 D bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 138834..141368 Escherichia coli str. K-12 substr. DH10B 6061336 YP_001729107.1 CDS fhuA NC_010473.1 141588 143831 D involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 141588..143831 Escherichia coli str. K-12 substr. DH10B 6062278 YP_001729108.1 CDS fhuC NC_010473.1 143882 144679 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 143882..144679 Escherichia coli str. K-12 substr. DH10B 6061278 YP_001729109.1 CDS fhuD NC_010473.1 144679 145569 D Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 144679..145569 Escherichia coli str. K-12 substr. DH10B 6061320 YP_001729110.1 CDS fhuB NC_010473.1 145566 147548 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 145566..147548 Escherichia coli str. K-12 substr. DH10B 6061265 YP_001729111.1 CDS hemL NC_010473.1 147706 148986 R Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase complement(147706..148986) Escherichia coli str. K-12 substr. DH10B 6062269 YP_001729112.1 CDS clcA NC_010473.1 149211 150632 D Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 149211..150632 Escherichia coli str. K-12 substr. DH10B 6061211 YP_001729113.1 CDS yadR NC_010473.1 150714 151058 D essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 150714..151058 Escherichia coli str. K-12 substr. DH10B 6061258 YP_001729114.1 CDS yadS NC_010473.1 151105 151728 R hypothetical protein complement(151105..151728) Escherichia coli str. K-12 substr. DH10B 6062317 YP_001729115.1 CDS btuF NC_010473.1 151766 152566 R solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF complement(151766..152566) Escherichia coli str. K-12 substr. DH10B 6060553 YP_001729116.1 CDS pfs NC_010473.1 152559 153257 R enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase complement(152559..153257) Escherichia coli str. K-12 substr. DH10B 6060549 YP_001729117.1 CDS dgt NC_010473.1 153341 154858 D forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 153341..154858 Escherichia coli str. K-12 substr. DH10B 6060649 YP_001729118.1 CDS degP NC_010473.1 154988 156412 D protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 154988..156412 Escherichia coli str. K-12 substr. DH10B 6060713 YP_001729119.1 CDS cdaR NC_010473.1 156567 157724 D regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 156567..157724 Escherichia coli str. K-12 substr. DH10B 6061301 YP_001729120.1 CDS yaeH NC_010473.1 157813 158199 R hypothetical protein complement(157813..158199) Escherichia coli str. K-12 substr. DH10B 6061246 YP_001729121.1 CDS yaeI NC_010473.1 158361 159173 R phosphodiesterase YaeI complement(158361..159173) Escherichia coli str. K-12 substr. DH10B 6062254 YP_001729122.1 CDS dapD NC_010473.1 159227 160051 R catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase complement(159227..160051) Escherichia coli str. K-12 substr. DH10B 6061233 YP_001729123.1 CDS glnD NC_010473.1 160082 162754 R catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase complement(160082..162754) Escherichia coli str. K-12 substr. DH10B 6061232 YP_001729124.1 CDS map NC_010473.1 162816 163610 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase complement(162816..163610) Escherichia coli str. K-12 substr. DH10B 6062247 YP_001729125.1 CDS rpsB NC_010473.1 163978 164703 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 163978..164703 Escherichia coli str. K-12 substr. DH10B 6059702 YP_001729126.1 CDS tsf NC_010473.1 164961 165812 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 164961..165812 Escherichia coli str. K-12 substr. DH10B 6061275 YP_001729127.1 CDS pyrH NC_010473.1 165959 166684 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 165959..166684 Escherichia coli str. K-12 substr. DH10B 6061269 YP_001729128.1 CDS frr NC_010473.1 166976 167533 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 166976..167533 Escherichia coli str. K-12 substr. DH10B 6061218 YP_001729129.1 CDS dxr NC_010473.1 167625 168821 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 167625..168821 Escherichia coli str. K-12 substr. DH10B 6061216 YP_001729130.1 CDS ispU NC_010473.1 169007 169768 D catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 169007..169768 Escherichia coli str. K-12 substr. DH10B 6061250 YP_001729131.1 CDS cdsA NC_010473.1 169781 170638 D catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 169781..170638 Escherichia coli str. K-12 substr. DH10B 6060529 YP_001729132.1 CDS rseP NC_010473.1 170650 172002 D catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 170650..172002 Escherichia coli str. K-12 substr. DH10B 6060701 YP_001729133.1 CDS ecfK NC_010473.1 172032 174464 D part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 172032..174464 Escherichia coli str. K-12 substr. DH10B 6060629 YP_001729134.1 CDS skp NC_010473.1 174586 175071 D periplasmic chaperone 174586..175071 Escherichia coli str. K-12 substr. DH10B 6060697 YP_001729135.1 CDS lpxD NC_010473.1 175075 176100 D adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 175075..176100 Escherichia coli str. K-12 substr. DH10B 6061150 YP_001729136.1 CDS fabZ NC_010473.1 176205 176660 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 176205..176660 Escherichia coli str. K-12 substr. DH10B 6061195 YP_001729137.1 CDS lpxA NC_010473.1 176664 177452 D catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 176664..177452 Escherichia coli str. K-12 substr. DH10B 6062258 YP_001729138.1 CDS lpxB NC_010473.1 177452 178600 D catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 177452..178600 Escherichia coli str. K-12 substr. DH10B 6061005 YP_001729139.1 CDS rnhB NC_010473.1 178597 179193 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 178597..179193 Escherichia coli str. K-12 substr. DH10B 6061147 YP_001729140.1 CDS dnaE NC_010473.1 179230 182712 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 179230..182712 Escherichia coli str. K-12 substr. DH10B 6061238 YP_001729141.1 CDS accA NC_010473.1 182725 183684 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 182725..183684 Escherichia coli str. K-12 substr. DH10B 6062185 YP_001729142.1 CDS ldcC NC_010473.1 183783 185924 D lysine decarboxylase 2, constitutive 183783..185924 Escherichia coli str. K-12 substr. DH10B 6061138 YP_001729143.1 CDS yaeR NC_010473.1 185981 186370 D hypothetical protein 185981..186370 Escherichia coli str. K-12 substr. DH10B 6061135 YP_001729144.1 CDS tilS NC_010473.1 186435 187733 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 186435..187733 Escherichia coli str. K-12 substr. DH10B 6061222 YP_001729145.1 CDS rof NC_010473.1 187782 188036 R Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator complement(187782..188036) Escherichia coli str. K-12 substr. DH10B 6062062 YP_001729146.1 CDS yaeP NC_010473.1 188029 188229 R hypothetical protein complement(188029..188229) Escherichia coli str. K-12 substr. DH10B 6062236 YP_001729147.1 CDS yaeQ NC_010473.1 188395 188940 D hypothetical protein 188395..188940 Escherichia coli str. K-12 substr. DH10B 6062233 YP_001729148.1 CDS yaeJ NC_010473.1 188937 189359 D peptidyl-tRNA hydrolase domain-containing protein 188937..189359 Escherichia coli str. K-12 substr. DH10B 6060616 YP_001729149.1 CDS nlpE NC_010473.1 189373 190083 D lipoprotein involved with copper homeostasis and adhesion 189373..190083 Escherichia coli str. K-12 substr. DH10B 6060499 YP_001729150.1 CDS yaeF NC_010473.1 190283 191107 R hypothetical protein complement(190283..191107) Escherichia coli str. K-12 substr. DH10B 6061203 YP_001729151.1 CDS proS NC_010473.1 191161 192879 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(191161..192879) Escherichia coli str. K-12 substr. DH10B 6061202 YP_001729152.1 CDS yaeB NC_010473.1 192991 193698 R hypothetical protein complement(192991..193698) Escherichia coli str. K-12 substr. DH10B 6061019 YP_001729153.1 CDS rcsF NC_010473.1 193695 194099 R outer membrane lipoprotein complement(193695..194099) Escherichia coli str. K-12 substr. DH10B 6062189 YP_001729154.1 CDS metQ NC_010473.1 194217 195032 R DL-methionine transporter substrate-binding subunit complement(194217..195032) Escherichia coli str. K-12 substr. DH10B 6062220 YP_001729155.1 CDS metI NC_010473.1 195072 195725 R part of the MetNIQ methionine uptake system; DL-methionine transporter permease complement(195072..195725) Escherichia coli str. K-12 substr. DH10B 6062218 YP_001729156.1 CDS metN NC_010473.1 195718 196749 R part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit complement(195718..196749) Escherichia coli str. K-12 substr. DH10B 6061111 YP_001729157.1 CDS gmhB NC_010473.1 196937 197512 D Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 196937..197512 Escherichia coli str. K-12 substr. DH10B 6061142 YP_001729158.1 CDS dkgB NC_010473.1 203271 204074 D catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 203271..204074 Escherichia coli str. K-12 substr. DH10B 6059800 YP_001729159.1 CDS yafC NC_010473.1 204071 204985 R DNA-binding transcriptional regulator complement(204071..204985) Escherichia coli str. K-12 substr. DH10B 6061101 YP_001729160.1 CDS yafD NC_010473.1 205226 206026 D hypothetical protein 205226..206026 Escherichia coli str. K-12 substr. DH10B 6061105 YP_001729161.1 CDS yafE NC_010473.1 206030 206653 D S-adenosyl-L-methionine-dependent methyltransferase 206030..206653 Escherichia coli str. K-12 substr. DH10B 6061095 YP_001729162.1 CDS mltD NC_010473.1 206701 208059 R catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D complement(206701..208059) Escherichia coli str. K-12 substr. DH10B 6060811 YP_001729163.1 CDS gloB NC_010473.1 208131 208886 R catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase complement(208131..208886) Escherichia coli str. K-12 substr. DH10B 6062135 YP_001729164.1 CDS yafS NC_010473.1 208920 209642 D S-adenosyl-L-methionine-dependent methyltransferase 208920..209642 Escherichia coli str. K-12 substr. DH10B 6060678 YP_001729165.1 CDS rnhA NC_010473.1 209639 210106 R An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H complement(209639..210106) Escherichia coli str. K-12 substr. DH10B 6060677 YP_001729166.1 CDS dnaQ NC_010473.1 210171 210902 D 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 210171..210902 Escherichia coli str. K-12 substr. DH10B 6061081 YP_001729167.1 CDS yafT NC_010473.1 211439 212224 D aminopeptidase 211439..212224 Escherichia coli str. K-12 substr. DH10B 6059983 YP_001729168.1 CDS yafV NC_010473.1 213523 214293 R hypothetical protein complement(213523..214293) Escherichia coli str. K-12 substr. DH10B 6060276 YP_001729169.1 CDS ivy NC_010473.1 214447 214920 D inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 214447..214920 Escherichia coli str. K-12 substr. DH10B 6061167 YP_001729170.1 CDS fadE NC_010473.1 214963 217407 R functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase complement(214963..217407) Escherichia coli str. K-12 substr. DH10B 6062199 YP_001729171.1 CDS gmhA NC_010473.1 217647 218225 D catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 217647..218225 Escherichia coli str. K-12 substr. DH10B 6061162 YP_001729172.1 CDS yafJ NC_010473.1 218431 219198 D contains the nonsynonymous change Q80L; amidotransferase 218431..219198 Escherichia coli str. K-12 substr. DH10B 6061121 YP_001729173.1 CDS yafK NC_010473.1 219169 219909 R hypothetical protein complement(219169..219909) Escherichia coli str. K-12 substr. DH10B 6061066 YP_001729174.1 CDS yafQ NC_010473.1 220065 220343 R toxin of the YafQ-DinJ toxin-antitoxin system complement(220065..220343) Escherichia coli str. K-12 substr. DH10B 6061153 YP_001729175.1 CDS dinJ NC_010473.1 220346 220606 R antitoxin of YafQ-DinJ toxin-antitoxin system complement(220346..220606) Escherichia coli str. K-12 substr. DH10B 6061114 YP_001729176.1 CDS yafL NC_010473.1 220816 221565 D contains synonymous mutation (G to T) at position 36; C40 family peptidase 220816..221565 Escherichia coli str. K-12 substr. DH10B 6061149 YP_001729177.1 CDS yafM NC_010473.1 221741 222238 D hypothetical protein 221741..222238 Escherichia coli str. K-12 substr. DH10B 6062152 YP_001729178.1 CDS dinB NC_010473.1 225002 226057 D involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 225002..226057 Escherichia coli str. K-12 substr. DH10B 6060198 YP_001729179.1 CDS yafN NC_010473.1 226109 226402 D putative antitoxin of the YafO-YafN toxin-antitoxin system 226109..226402 Escherichia coli str. K-12 substr. DH10B 6061100 YP_001729180.1 CDS yafO NC_010473.1 226405 226803 D YafO overproduction induces toxicity; it is believed to be the toxin of a toxin-antitoxin pair; unknown function; putative toxin YafO 226405..226803 Escherichia coli str. K-12 substr. DH10B 6060580 YP_001729181.1 CDS yafP NC_010473.1 226813 227265 D hypothetical protein 226813..227265 Escherichia coli str. K-12 substr. DH10B 6060584 YP_001729182.1 CDS pepD NC_010473.1 228363 229820 R aminoacyl-histidine dipeptidase complement(228363..229820) Escherichia coli str. K-12 substr. DH10B 6060105 YP_001729183.1 CDS gpt NC_010473.1 230081 230539 D catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 230081..230539 Escherichia coli str. K-12 substr. DH10B 6060518 YP_001729184.1 CDS frsA NC_010473.1 230631 231875 D forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 230631..231875 Escherichia coli str. K-12 substr. DH10B 6061367 YP_001729185.1 CDS crl NC_010473.1 231933 232334 D involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 231933..232334 Escherichia coli str. K-12 substr. DH10B 6061454 YP_001729186.1 CDS phoE NC_010473.1 232373 233428 R outer membrane phosphoporin protein E complement(232373..233428) Escherichia coli str. K-12 substr. DH10B 6061732 YP_001729187.1 CDS proB NC_010473.1 233716 234819 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 233716..234819 Escherichia coli str. K-12 substr. DH10B 6061924 YP_001729188.1 CDS proA NC_010473.1 234831 236084 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 234831..236084 Escherichia coli str. K-12 substr. DH10B 6061964 YP_001729189.1 CDS ykfI NC_010473.1 236656 236997 R CP4-6 prophage; toxin of the YkfI-YafW toxin-antitoxin system complement(236656..236997) Escherichia coli str. K-12 substr. DH10B 6058464 YP_001729190.1 CDS yafW NC_010473.1 237018 237335 R CP4-6 prophage; antitoxin of the YkfI-YafW toxin-antitoxin system complement(237018..237335) Escherichia coli str. K-12 substr. DH10B 6062075 YP_001729191.1 CDS ykfH NC_010473.1 237354 237575 R hypothetical protein complement(237354..237575) Escherichia coli str. K-12 substr. DH10B 6062127 YP_001729192.1 CDS ykfG NC_010473.1 237584 238060 R CP4-6 prophage; DNA repair protein complement(237584..238060) Escherichia coli str. K-12 substr. DH10B 6062145 YP_001729193.1 CDS yafX NC_010473.1 238076 238534 R CP4-6 prophage; hypothetical protein complement(238076..238534) Escherichia coli str. K-12 substr. DH10B 6062115 YP_001729194.1 CDS ykfF NC_010473.1 238632 238871 R CP4-6 prophage; hypothetical protein complement(238632..238871) Escherichia coli str. K-12 substr. DH10B 6062168 YP_001729195.1 CDS ykfB NC_010473.1 238948 239415 R CP4-6 prophage; hypothetical protein complement(238948..239415) Escherichia coli str. K-12 substr. DH10B 6062179 YP_001729196.1 CDS yafY NC_010473.1 239438 239881 R CP4-6 prophage; inner membrane lipoprotein complement(239438..239881) Escherichia coli str. K-12 substr. DH10B 6062150 YP_001729197.1 CDS yafZ NC_010473.1 240512 241333 R CP4-6 prophage; hypothetical protein complement(240512..241333) Escherichia coli str. K-12 substr. DH10B 6059344 YP_001729198.1 CDS ykfA NC_010473.1 241425 242288 R CP4-6 prophage; GTP-binding protein complement(241425..242288) Escherichia coli str. K-12 substr. DH10B 6062289 YP_001729199.1 CDS perR NC_010473.1 242617 243510 R CP4-6 prophage; DNA-binding transcriptional regulator complement(242617..243510) Escherichia coli str. K-12 substr. DH10B 6062299 YP_001729200.1 CDS insN-1 NC_010473.1 243570 243974 D CP4-6 prophage; partial regulator of insertion element IS911A 243570..243974 Escherichia coli str. K-12 substr. DH10B 6062302 YP_001729201.1 CDS insI-1 NC_010473.1 243931 245082 D CP4-6 prophage; IS30 transposase 243931..245082 Escherichia coli str. K-12 substr. DH10B 6062312 YP_001729202.1 CDS insO-1 NC_010473.1 245158 245583 D CP4-6 prophage; partial transposase of insertion element IS911A 245158..245583 Escherichia coli str. K-12 substr. DH10B 6062213 YP_001729203.1 CDS insH-1 NC_010473.1 247429 248445 R CP4-6 prophage; IS5 transposase and trans-activator complement(247429..248445) Escherichia coli str. K-12 substr. DH10B 6059560 YP_001729204.1 CDS mmuP NC_010473.1 248653 250056 D S-methylmethionine transporter 248653..250056 Escherichia coli str. K-12 substr. DH10B 6062339 YP_001729205.1 CDS mmuM NC_010473.1 250043 250975 D converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; homocysteine methyltransferase 250043..250975 Escherichia coli str. K-12 substr. DH10B 6062419 YP_001729206.1 CDS fbpC NC_010473.1 251084 252130 R Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import; ferric transporter ATP-binding subunit complement(251084..252130) Escherichia coli str. K-12 substr. DH10B 6060364 YP_001729207.1 CDS afuB NC_010473.1 252142 252504 R CP4-6 prophage; ferric ABC transporter membrane protein complement(252142..252504) Escherichia coli str. K-12 substr. DH10B 6062282 YP_001729208.1 CDS insB-2 NC_010473.1 252506 253009 R CP4-6 prophage; IS1 transposase InsAB' complement(252506..253009) Escherichia coli str. K-12 substr. DH10B 6062407 YP_001729209.1 CDS insA-2 NC_010473.1 252928 253203 R CP4-6 prophage; IS1 repressor protein InsA complement(252928..253203) Escherichia coli str. K-12 substr. DH10B 6062389 YP_001729210.1 CDS ykgN NC_010473.1 253352 253690 R IS protein complement(253352..253690) Escherichia coli str. K-12 substr. DH10B 6062382 YP_001729211.1 CDS yagB NC_010473.1 253713 254063 R CP4-6 prophage; hypothetical protein complement(253713..254063) Escherichia coli str. K-12 substr. DH10B 6062323 YP_001729212.1 CDS yagA NC_010473.1 254157 255311 R CP4-6 prophage; DNA-binding transcriptional regulator complement(254157..255311) Escherichia coli str. K-12 substr. DH10B 6062417 YP_001729213.1 CDS yagE NC_010473.1 255585 256514 D CP4-6 prophage; lyase/synthase 255585..256514 Escherichia coli str. K-12 substr. DH10B 6060903 YP_001729214.1 CDS yagF NC_010473.1 256529 258496 D contains synonymous mutation (T to G) at position 1335; hypothetical protein 256529..258496 Escherichia coli str. K-12 substr. DH10B 6062281 YP_001729215.1 CDS yagG NC_010473.1 258723 260105 D uncharacterized member of the GPH family of galactose-pentose-hexuronide transporters; putative symporter YagG 258723..260105 Escherichia coli str. K-12 substr. DH10B 6058916 YP_001729216.1 CDS yagH NC_010473.1 260117 261727 D CP4-6 prophage; xylosidase/arabinosidase 260117..261727 Escherichia coli str. K-12 substr. DH10B 6058952 YP_001729217.1 CDS argF NC_010473.1 264075 265079 R catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase; when both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III; ornithine carbamoyltransferase subunit F complement(264075..265079) Escherichia coli str. K-12 substr. DH10B 6060287 YP_001729218.1 CDS insB-3 NC_010473.1 265423 265926 R CP4-6 prophage; IS1 transposase InsAB' complement(265423..265926) Escherichia coli str. K-12 substr. DH10B 6061877 YP_001729219.1 CDS insA-3 NC_010473.1 265845 266120 R CP4-6 prophage; IS1 repressor protein InsA complement(265845..266120) Escherichia coli str. K-12 substr. DH10B 6062170 YP_001729220.1 CDS yagJ NC_010473.1 266274 267005 D CP4-6 prophage; hypothetical protein 266274..267005 Escherichia coli str. K-12 substr. DH10B 6062311 YP_001729221.1 CDS yagK NC_010473.1 267096 267722 R CP4-6 prophage; hypothetical protein complement(267096..267722) Escherichia coli str. K-12 substr. DH10B 6058896 YP_001729222.1 CDS yagL NC_010473.1 267994 268692 R CP4-6 prophage; DNA-binding protein complement(267994..268692) Escherichia coli str. K-12 substr. DH10B 6059304 YP_001729223.1 CDS yagM NC_010473.1 268719 269573 R CP4-6 prophage; hypothetical protein complement(268719..269573) Escherichia coli str. K-12 substr. DH10B 6059821 YP_001729224.1 CDS yagN NC_010473.1 269913 270353 R CP4-6 prophage; hypothetical protein complement(269913..270353) Escherichia coli str. K-12 substr. DH10B 6060265 YP_001729225.1 CDS intF NC_010473.1 270470 271870 R CP4-6 prophage; phage integrase complement(270470..271870) Escherichia coli str. K-12 substr. DH10B 6060277 YP_001729226.1 CDS yagP NC_010473.1 272155 272565 R transcriptional regulator complement(272155..272565) Escherichia coli str. K-12 substr. DH10B 6062079 YP_001729227.1 CDS yagQ NC_010473.1 272544 273500 R hypothetical protein complement(272544..273500) Escherichia coli str. K-12 substr. DH10B 6060039 YP_001729228.1 CDS yagR NC_010473.1 273510 275708 R oxidoreductase complement(273510..275708) Escherichia coli str. K-12 substr. DH10B 6061894 YP_001729229.1 CDS yagS NC_010473.1 275705 276661 R oxidoreductase complement(275705..276661) Escherichia coli str. K-12 substr. DH10B 6062103 YP_001729230.1 CDS yagT NC_010473.1 276658 277347 R putative xanthine dehydrogenase iron-sulfur-binding subunit complement(276658..277347) Escherichia coli str. K-12 substr. DH10B 6058920 YP_001729231.1 CDS yagU NC_010473.1 277765 278379 D inner membrane protein 277765..278379 Escherichia coli str. K-12 substr. DH10B 6059793 YP_001729232.1 CDS ykgJ NC_010473.1 278627 278956 R ferredoxin complement(278627..278956) Escherichia coli str. K-12 substr. DH10B 6059806 YP_001729233.1 CDS yagV NC_010473.1 279269 279979 R hypothetical protein complement(279269..279979) Escherichia coli str. K-12 substr. DH10B 6061933 YP_001729234.1 CDS yagW NC_010473.1 279948 281591 R receptor complement(279948..281591) Escherichia coli str. K-12 substr. DH10B 6061579 YP_001729235.1 CDS yagX NC_010473.1 281581 284106 R aromatic compound dioxygenase complement(281581..284106) Escherichia coli str. K-12 substr. DH10B 6061133 YP_001729236.1 CDS matC NC_010473.1 284132 284800 R hypothetical protein complement(284132..284800) Escherichia coli str. K-12 substr. DH10B 6060675 YP_001729237.1 CDS matB NC_010473.1 284858 285445 R MAT fimbrillin complement(284858..285445) Escherichia coli str. K-12 substr. DH10B 6061956 YP_001729238.1 CDS matA NC_010473.1 285520 286110 R regulator complement(285520..286110) Escherichia coli str. K-12 substr. DH10B 6058216 YP_001729239.1 CDS ykgL NC_010473.1 286886 287113 D hypothetical protein 286886..287113 Escherichia coli str. K-12 substr. DH10B 6058242 YP_001729240.1 CDS rpmJ NC_010473.1 287148 287288 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 complement(287148..287288) Escherichia coli str. K-12 substr. DH10B 6058268 YP_001729241.1 CDS rpmE2 NC_010473.1 287288 287551 R RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(287288..287551) Escherichia coli str. K-12 substr. DH10B 6058420 YP_001729242.1 CDS eaeH NC_010473.1 289131 290018 D attaching and effacing protein, pathogenesis factor 289131..290018 Escherichia coli str. K-12 substr. DH10B 6058618 YP_001729243.1 CDS insE-1 NC_010473.1 290056 290364 D IS3 element protein InsE 290056..290364 Escherichia coli str. K-12 substr. DH10B 6059106 YP_001729244.1 CDS insF-1 NC_010473.1 290361 291227 D IS3 element protein InsF 290361..291227 Escherichia coli str. K-12 substr. DH10B 6058762 YP_001729245.1 CDS ykgA NC_010473.1 291224 291910 R DNA-binding transcriptional regulator complement(291224..291910) Escherichia coli str. K-12 substr. DH10B 6058881 YP_001729246.1 CDS ykgB NC_010473.1 292500 293093 R inner membrane protein complement(292500..293093) Escherichia coli str. K-12 substr. DH10B 6059081 YP_001729247.1 CDS ykgI NC_010473.1 293105 293341 R hypothetical protein complement(293105..293341) Escherichia coli str. K-12 substr. DH10B 6059116 YP_001729248.1 CDS ykgC NC_010473.1 293450 294775 R Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase complement(293450..294775) Escherichia coli str. K-12 substr. DH10B 6059121 YP_001729249.1 CDS ykgD NC_010473.1 295001 295855 D DNA-binding transcriptional regulator 295001..295855 Escherichia coli str. K-12 substr. DH10B 6059137 YP_001729250.1 CDS ykgE NC_010473.1 296382 297101 D oxidoreductase 296382..297101 Escherichia coli str. K-12 substr. DH10B 6059167 YP_001729251.1 CDS ykgF NC_010473.1 297112 298539 D amino acid dehydrogenase 297112..298539 Escherichia coli str. K-12 substr. DH10B 6059187 YP_001729252.1 CDS ykgG NC_010473.1 298532 299227 D transporter 298532..299227 Escherichia coli str. K-12 substr. DH10B 6059198 YP_001729253.1 CDS ykgH NC_010473.1 299470 300138 R inner membrane protein complement(299470..300138) Escherichia coli str. K-12 substr. DH10B 6059205 YP_001729254.1 CDS betA NC_010473.1 300351 302021 R catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase complement(300351..302021) Escherichia coli str. K-12 substr. DH10B 6059685 YP_001729255.1 CDS betB NC_010473.1 302035 303507 R catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase complement(302035..303507) Escherichia coli str. K-12 substr. DH10B 6059213 YP_001729256.1 CDS betI NC_010473.1 303521 304108 R HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI complement(303521..304108) Escherichia coli str. K-12 substr. DH10B 6059246 YP_001729257.1 CDS betT NC_010473.1 304237 306270 D proton-motive-force-driven choline transporter; choline transport protein BetT 304237..306270 Escherichia coli str. K-12 substr. DH10B 6059248 YP_001729258.1 CDS yahA NC_010473.1 307145 308233 D DNA-binding transcriptional regulator 307145..308233 Escherichia coli str. K-12 substr. DH10B 6059249 YP_001729259.1 CDS yahB NC_010473.1 308275 309207 R DNA-binding transcriptional regulator complement(308275..309207) Escherichia coli str. K-12 substr. DH10B 6059254 YP_001729260.1 CDS yahC NC_010473.1 309299 309796 R inner membrane protein complement(309299..309796) Escherichia coli str. K-12 substr. DH10B 6059257 YP_001729261.1 CDS yahD NC_010473.1 310054 310659 D transcriptional regulator 310054..310659 Escherichia coli str. K-12 substr. DH10B 6059261 YP_001729262.1 CDS yahE NC_010473.1 310699 311562 D hypothetical protein 310699..311562 Escherichia coli str. K-12 substr. DH10B 6059280 YP_001729263.1 CDS yahF NC_010473.1 311552 313099 D acyl-CoA synthetase 311552..313099 Escherichia coli str. K-12 substr. DH10B 6059281 YP_001729264.1 CDS mhpT NC_010473.1 314014 315225 D putative 3-hydroxyphenylpropionic transporter MhpT 314014..315225 Escherichia coli str. K-12 substr. DH10B 6059282 YP_001729265.1 CDS yaiL NC_010473.1 315327 315866 D nucleoprotein/polynucleotide-associated enzyme 315327..315866 Escherichia coli str. K-12 substr. DH10B 6059284 YP_001729266.1 CDS frmB NC_010473.1 316090 316923 R esterase complement(316090..316923) Escherichia coli str. K-12 substr. DH10B 6059309 YP_001729267.1 CDS frmA NC_010473.1 317017 318126 R alcohol dehydrogenase complement(317017..318126) Escherichia coli str. K-12 substr. DH10B 6059313 YP_001729268.1 CDS frmR NC_010473.1 318161 318436 R formaldehyde-induced negative regulator of the frmRAB operon; regulator protein FrmR complement(318161..318436) Escherichia coli str. K-12 substr. DH10B 6059318 YP_001729269.1 CDS yaiO NC_010473.1 318624 319397 R hypothetical protein complement(318624..319397) Escherichia coli str. K-12 substr. DH10B 6059321 YP_001729270.1 CDS insC-1 NC_010473.1 319861 320271 D IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 319861..320271 Escherichia coli str. K-12 substr. DH10B 6059144 YP_001729271.1 CDS insD-1 NC_010473.1 320229 321134 D IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 320229..321134 Escherichia coli str. K-12 substr. DH10B 6059120 YP_001729272.1 CDS yaiP NC_010473.1 321294 322490 R glucosyltransferase complement(321294..322490) Escherichia coli str. K-12 substr. DH10B 6059324 YP_001729273.1 CDS yaiS NC_010473.1 322614 323171 R hypothetical protein complement(322614..323171) Escherichia coli str. K-12 substr. DH10B 6059325 YP_001729274.1 CDS tauA NC_010473.1 323787 324749 D with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 323787..324749 Escherichia coli str. K-12 substr. DH10B 6059327 YP_001729275.1 CDS tauB NC_010473.1 324762 325529 D Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit 324762..325529 Escherichia coli str. K-12 substr. DH10B 6059331 YP_001729276.1 CDS tauC NC_010473.1 325526 326353 D taurine transporter subunit 325526..326353 Escherichia coli str. K-12 substr. DH10B 6059337 YP_001729277.1 CDS tauD NC_010473.1 326350 327201 D catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 326350..327201 Escherichia coli str. K-12 substr. DH10B 6059341 YP_001729278.1 CDS hemB NC_010473.1 327308 328282 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(327308..328282) Escherichia coli str. K-12 substr. DH10B 6059343 YP_001729279.1 CDS ykiB NC_010473.1 328452 328721 R hypothetical protein complement(328452..328721) Escherichia coli str. K-12 substr. DH10B 6059354 YP_001729280.1 CDS insF-2 NC_010473.1 330294 331160 R IS3 element protein InsF complement(330294..331160) Escherichia coli str. K-12 substr. DH10B 6058693 YP_001729281.1 CDS insE-2 NC_010473.1 331157 331465 R IS3 element protein InsE complement(331157..331465) Escherichia coli str. K-12 substr. DH10B 6059361 YP_001729282.1 CDS yaiV NC_010473.1 333016 333684 D putative DNA-binding transcriptional regulator 333016..333684 Escherichia coli str. K-12 substr. DH10B 6059376 YP_001729283.1 CDS ampH NC_010473.1 333685 334842 R this protein has no known enzymatic function; beta-lactam binding protein AmpH complement(333685..334842) Escherichia coli str. K-12 substr. DH10B 6059396 YP_001729284.1 CDS sbmA NC_010473.1 335194 336414 D in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transporter 335194..336414 Escherichia coli str. K-12 substr. DH10B 6059398 YP_001729285.1 CDS yaiW NC_010473.1 336427 337521 D DNA-binding transcriptional regulator 336427..337521 Escherichia coli str. K-12 substr. DH10B 6059400 YP_001729286.1 CDS yaiY NC_010473.1 337580 337888 R inner membrane protein complement(337580..337888) Escherichia coli str. K-12 substr. DH10B 6059401 YP_001729287.1 CDS yaiZ NC_010473.1 338148 338360 D inner membrane protein 338148..338360 Escherichia coli str. K-12 substr. DH10B 6059406 YP_001729288.1 CDS ddl NC_010473.1 338384 339478 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(338384..339478) Escherichia coli str. K-12 substr. DH10B 6059408 YP_001729289.1 CDS iraP NC_010473.1 339941 340201 D hypothetical protein 339941..340201 Escherichia coli str. K-12 substr. DH10B 6059414 YP_001729290.1 CDS phoA NC_010473.1 340302 341717 D alkaline phosphatase 340302..341717 Escherichia coli str. K-12 substr. DH10B 6059419 YP_001729291.1 CDS psiF NC_010473.1 341836 342156 D hypothetical protein 341836..342156 Escherichia coli str. K-12 substr. DH10B 6059422 YP_001729292.1 CDS adrA NC_010473.1 342258 343373 D catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 342258..343373 Escherichia coli str. K-12 substr. DH10B 6059436 YP_001729293.1 CDS proC NC_010473.1 343390 344199 R catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase complement(343390..344199) Escherichia coli str. K-12 substr. DH10B 6059440 YP_001729294.1 CDS yaiI NC_010473.1 344319 344777 D hypothetical protein 344319..344777 Escherichia coli str. K-12 substr. DH10B 6059443 YP_001729295.1 CDS aroL NC_010473.1 344960 345484 D type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 344960..345484 Escherichia coli str. K-12 substr. DH10B 6059445 YP_001729296.1 CDS yaiA NC_010473.1 345534 345725 D hypothetical protein 345534..345725 Escherichia coli str. K-12 substr. DH10B 6059449 YP_001729297.1 CDS aroM NC_010473.1 345983 346660 D hypothetical protein 345983..346660 Escherichia coli str. K-12 substr. DH10B 6059454 YP_001729298.1 CDS yaiE NC_010473.1 346732 347016 D hypothetical protein 346732..347016 Escherichia coli str. K-12 substr. DH10B 6059457 YP_001729299.1 CDS ykiA NC_010473.1 347224 347505 D hypothetical protein 347224..347505 Escherichia coli str. K-12 substr. DH10B 6059462 YP_001729300.1 CDS rdgC NC_010473.1 347663 348574 R Required for efficient pilin antigenic variation; recombination associated protein complement(347663..348574) Escherichia coli str. K-12 substr. DH10B 6059464 YP_001729301.1 CDS mak NC_010473.1 348699 349607 D catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 348699..349607 Escherichia coli str. K-12 substr. DH10B 6059467 YP_001729302.1 CDS araJ NC_010473.1 349852 351036 R member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers; MFS transport protein AraJ complement(349852..351036) Escherichia coli str. K-12 substr. DH10B 6059134 YP_001729303.1 CDS sbcC NC_010473.1 351162 354308 R with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease subunit SbcC complement(351162..354308) Escherichia coli str. K-12 substr. DH10B 6059475 YP_001729304.1 CDS sbcD NC_010473.1 354305 355507 R with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease subunit SbcD complement(354305..355507) Escherichia coli str. K-12 substr. DH10B 6059477 YP_001729305.1 CDS phoB NC_010473.1 355697 356386 D two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB 355697..356386 Escherichia coli str. K-12 substr. DH10B 6059481 YP_001729306.1 CDS phoR NC_010473.1 356444 357739 D membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 356444..357739 Escherichia coli str. K-12 substr. DH10B 6059488 YP_001729307.1 CDS brnQ NC_010473.1 358146 359465 D branched chain amino acid ABC transporter 358146..359465 Escherichia coli str. K-12 substr. DH10B 6059495 YP_001729308.1 CDS proY NC_010473.1 359541 360914 D cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; putative proline-specific permease 359541..360914 Escherichia coli str. K-12 substr. DH10B 6059496 YP_001729309.1 CDS malZ NC_010473.1 361070 362887 D maltodextrin glucosidase 361070..362887 Escherichia coli str. K-12 substr. DH10B 6059498 YP_001729310.1 CDS acpH NC_010473.1 362892 363473 R Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; acyl carrier protein phosphodiesterase complement(362892..363473) Escherichia coli str. K-12 substr. DH10B 6059506 YP_001729311.1 CDS queA NC_010473.1 363566 364636 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 363566..364636 Escherichia coli str. K-12 substr. DH10B 6059509 YP_001729312.1 CDS tgt NC_010473.1 364692 365819 D Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 364692..365819 Escherichia coli str. K-12 substr. DH10B 6059510 YP_001729313.1 CDS yajC NC_010473.1 365842 366174 D member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 365842..366174 Escherichia coli str. K-12 substr. DH10B 6060241 YP_001729314.1 CDS secD NC_010473.1 366202 368049 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 366202..368049 Escherichia coli str. K-12 substr. DH10B 6059511 YP_001729315.1 CDS secF NC_010473.1 368060 369031 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 368060..369031 Escherichia coli str. K-12 substr. DH10B 6059515 YP_001729316.1 CDS yajD NC_010473.1 369160 369507 D hypothetical protein 369160..369507 Escherichia coli str. K-12 substr. DH10B 6059517 YP_001729317.1 CDS tsx NC_010473.1 369684 370568 R nucleoside channel phage T6/colicin K receptor complement(369684..370568) Escherichia coli str. K-12 substr. DH10B 6059520 YP_001729318.1 CDS yajI NC_010473.1 370867 371406 R hypothetical protein complement(370867..371406) Escherichia coli str. K-12 substr. DH10B 6059524 YP_001729319.1 CDS nrdR NC_010473.1 371557 372006 D transcriptional regulator NrdR 371557..372006 Escherichia coli str. K-12 substr. DH10B 6059529 YP_001729320.1 CDS ribD NC_010473.1 372010 373113 D riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 372010..373113 Escherichia coli str. K-12 substr. DH10B 6059530 YP_001729321.1 CDS ribH NC_010473.1 373202 373672 D RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 373202..373672 Escherichia coli str. K-12 substr. DH10B 6059532 YP_001729322.1 CDS nusB NC_010473.1 373692 374111 D Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 373692..374111 Escherichia coli str. K-12 substr. DH10B 6059533 YP_001729323.1 CDS thiL NC_010473.1 374189 375166 D catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 374189..375166 Escherichia coli str. K-12 substr. DH10B 6059535 YP_001729324.1 CDS pgpA NC_010473.1 375144 375662 D hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 375144..375662 Escherichia coli str. K-12 substr. DH10B 6059537 YP_001729325.1 CDS yajO NC_010473.1 375716 376690 R oxidoreductase, NAD(P)-binding complement(375716..376690) Escherichia coli str. K-12 substr. DH10B 6059542 YP_001729326.1 CDS dxs NC_010473.1 376870 378732 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(376870..378732) Escherichia coli str. K-12 substr. DH10B 6059543 YP_001729327.1 CDS ispA NC_010473.1 378757 379656 R geranyltranstransferase complement(378757..379656) Escherichia coli str. K-12 substr. DH10B 6059545 YP_001729328.1 CDS xseB NC_010473.1 379656 379898 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(379656..379898) Escherichia coli str. K-12 substr. DH10B 6059548 YP_001729329.1 CDS thiI NC_010473.1 380104 381552 D Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 380104..381552 Escherichia coli str. K-12 substr. DH10B 6059550 YP_001729330.1 CDS yajL NC_010473.1 381606 382196 R DJ-1 family protein complement(381606..382196) Escherichia coli str. K-12 substr. DH10B 6059551 YP_001729331.1 CDS panE NC_010473.1 382159 383070 R ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase complement(382159..383070) Escherichia coli str. K-12 substr. DH10B 6059554 YP_001729332.1 CDS yajQ NC_010473.1 383238 383729 D putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; putative nucleotide-binding protein 383238..383729 Escherichia coli str. K-12 substr. DH10B 6059555 YP_001729333.1 CDS yajR NC_010473.1 383857 385221 R transporter complement(383857..385221) Escherichia coli str. K-12 substr. DH10B 6059556 YP_001729334.1 CDS cyoE NC_010473.1 385370 386260 R converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase complement(385370..386260) Escherichia coli str. K-12 substr. DH10B 6059559 YP_001729335.1 CDS cyoD NC_010473.1 386272 386601 R cytochrome o ubiquinol oxidase subunit IV complement(386272..386601) Escherichia coli str. K-12 substr. DH10B 6059561 YP_001729336.1 CDS cyoC NC_010473.1 386601 387215 R cytochrome o ubiquinol oxidase subunit III complement(386601..387215) Escherichia coli str. K-12 substr. DH10B 6059562 YP_001729337.1 CDS cyoB NC_010473.1 387205 389196 R cytochrome o ubiquinol oxidase subunit I complement(387205..389196) Escherichia coli str. K-12 substr. DH10B 6059565 YP_001729338.1 CDS cyoA NC_010473.1 389218 390165 R cytochrome o ubiquinol oxidase subunit II complement(389218..390165) Escherichia coli str. K-12 substr. DH10B 6059567 YP_001729339.1 CDS ampG NC_010473.1 390625 392100 R in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter complement(390625..392100) Escherichia coli str. K-12 substr. DH10B 6059568 YP_001729340.1 CDS yajG NC_010473.1 392144 392722 R hypothetical protein complement(392144..392722) Escherichia coli str. K-12 substr. DH10B 6059575 YP_001729341.1 CDS bolA NC_010473.1 393027 393344 D positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 393027..393344 Escherichia coli str. K-12 substr. DH10B 6059577 YP_001729342.1 CDS tig NC_010473.1 393688 394986 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 393688..394986 Escherichia coli str. K-12 substr. DH10B 6059583 YP_001729343.1 CDS clpP NC_010473.1 395232 395855 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 395232..395855 Escherichia coli str. K-12 substr. DH10B 6059592 YP_001729344.1 CDS clpX NC_010473.1 395981 397255 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 395981..397255 Escherichia coli str. K-12 substr. DH10B 6059595 YP_001729345.1 CDS lon NC_010473.1 397443 399797 D DNA-binding ATP-dependent protease La 397443..399797 Escherichia coli str. K-12 substr. DH10B 6059596 YP_001729346.1 CDS hupB NC_010473.1 400006 400278 D histone-like DNA-binding protein; transcriptional regulator HU subunit beta 400006..400278 Escherichia coli str. K-12 substr. DH10B 6059598 YP_001729347.1 CDS ppiD NC_010473.1 400470 402341 D peptidyl-prolyl cis-trans isomerase 400470..402341 Escherichia coli str. K-12 substr. DH10B 6059607 YP_001729348.1 CDS ybaV NC_010473.1 402492 402863 D hypothetical protein 402492..402863 Escherichia coli str. K-12 substr. DH10B 6059608 YP_001729349.1 CDS ybaW NC_010473.1 402957 403355 D hypothetical protein 402957..403355 Escherichia coli str. K-12 substr. DH10B 6059611 YP_001729350.1 CDS queC NC_010473.1 403407 404102 R YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC complement(403407..404102) Escherichia coli str. K-12 substr. DH10B 6059632 YP_001729351.1 CDS ybaE NC_010473.1 404167 405867 R ABC transporter substrate-binding protein complement(404167..405867) Escherichia coli str. K-12 substr. DH10B 6059633 YP_001729352.1 CDS cof NC_010473.1 405967 406785 D thiamin pyrimidine pyrophosphate hydrolase 405967..406785 Escherichia coli str. K-12 substr. DH10B 6059635 YP_001729353.1 CDS ybaO NC_010473.1 406938 407396 D DNA-binding transcriptional regulator 406938..407396 Escherichia coli str. K-12 substr. DH10B 6059649 YP_001729354.1 CDS mdlA NC_010473.1 407426 409198 D putative multidrug transporter membrane\ATP-binding components 407426..409198 Escherichia coli str. K-12 substr. DH10B 6059650 YP_001729355.1 CDS mdlB NC_010473.1 409191 410972 D putative multidrug transporter membrane\ATP-binding components 409191..410972 Escherichia coli str. K-12 substr. DH10B 6059653 YP_001729356.1 CDS glnK NC_010473.1 411153 411491 D indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 411153..411491 Escherichia coli str. K-12 substr. DH10B 6059664 YP_001729357.1 CDS amtB NC_010473.1 411521 412807 D ammonium transporter 411521..412807 Escherichia coli str. K-12 substr. DH10B 6059668 YP_001729358.1 CDS tesB NC_010473.1 412856 413716 R acyl-CoA thioesterase II complement(412856..413716) Escherichia coli str. K-12 substr. DH10B 6059671 YP_001729359.1 CDS ybaY NC_010473.1 413934 414506 D outer membrane lipoprotein 413934..414506 Escherichia coli str. K-12 substr. DH10B 6059672 YP_001729360.1 CDS ybaZ NC_010473.1 414537 414926 R methyltransferase complement(414537..414926) Escherichia coli str. K-12 substr. DH10B 6059674 YP_001729361.1 CDS ybaA NC_010473.1 415227 415580 D hypothetical protein 415227..415580 Escherichia coli str. K-12 substr. DH10B 6061734 YP_001729362.1 CDS ylaB NC_010473.1 415622 417172 R inner membrane protein complement(415622..417172) Escherichia coli str. K-12 substr. DH10B 6059678 YP_001729363.1 CDS ylaC NC_010473.1 417336 417806 R inner membrane protein complement(417336..417806) Escherichia coli str. K-12 substr. DH10B 6059681 YP_001729364.1 CDS maa NC_010473.1 417922 418473 R maltose O-acetyltransferase complement(417922..418473) Escherichia coli str. K-12 substr. DH10B 6059684 YP_001729365.1 CDS hha NC_010473.1 418645 418863 R with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein complement(418645..418863) Escherichia coli str. K-12 substr. DH10B 6059976 YP_001729366.1 CDS ybaJ NC_010473.1 418889 419263 R hypothetical protein complement(418889..419263) Escherichia coli str. K-12 substr. DH10B 6059688 YP_001729367.1 CDS acrB NC_010473.1 419809 422958 R multidrug efflux system protein complement(419809..422958) Escherichia coli str. K-12 substr. DH10B 6059690 YP_001729368.1 CDS acrA NC_010473.1 422981 424174 R multidrug efflux system complement(422981..424174) Escherichia coli str. K-12 substr. DH10B 6059692 YP_001729369.1 CDS acrR NC_010473.1 424316 424963 D regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 424316..424963 Escherichia coli str. K-12 substr. DH10B 6059695 YP_001729370.1 CDS kefA NC_010473.1 425091 428453 D small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 425091..428453 Escherichia coli str. K-12 substr. DH10B 6059697 YP_001729371.1 CDS ybaM NC_010473.1 428665 428826 R hypothetical protein complement(428665..428826) Escherichia coli str. K-12 substr. DH10B 6059700 YP_001729372.1 CDS priC NC_010473.1 428840 429367 R PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' complement(428840..429367) Escherichia coli str. K-12 substr. DH10B 6059708 YP_001729373.1 CDS ybaN NC_010473.1 429437 429814 D hypothetical protein 429437..429814 Escherichia coli str. K-12 substr. DH10B 6059719 YP_001729374.1 CDS apt NC_010473.1 429967 430518 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 429967..430518 Escherichia coli str. K-12 substr. DH10B 6059725 YP_001729375.1 CDS dnaX NC_010473.1 430647 432578 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 430647..432578 Escherichia coli str. K-12 substr. DH10B 6059726 YP_001729376.1 CDS ybaB NC_010473.1 432631 432960 D hypothetical protein 432631..432960 Escherichia coli str. K-12 substr. DH10B 6059732 YP_001729377.1 CDS recR NC_010473.1 432960 433565 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 432960..433565 Escherichia coli str. K-12 substr. DH10B 6059736 YP_001729378.1 CDS htpG NC_010473.1 433675 435549 D molecular chaperone; heat shock protein 90 433675..435549 Escherichia coli str. K-12 substr. DH10B 6059744 YP_001729379.1 CDS adk NC_010473.1 435730 436374 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 435730..436374 Escherichia coli str. K-12 substr. DH10B 6059750 YP_001729380.1 CDS hemH NC_010473.1 436610 437572 D protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 436610..437572 Escherichia coli str. K-12 substr. DH10B 6059765 YP_001729381.1 CDS aes NC_010473.1 437569 438528 R acetyl esterase complement(437569..438528) Escherichia coli str. K-12 substr. DH10B 6059767 YP_001729382.1 CDS gsk NC_010473.1 438680 439984 D inosine/guanosine kinase 438680..439984 Escherichia coli str. K-12 substr. DH10B 6059770 YP_001729383.1 CDS ybaL NC_010473.1 440117 441793 R YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; putative cation:proton antiport protein complement(440117..441793) Escherichia coli str. K-12 substr. DH10B 6059774 YP_001729384.1 CDS fsr NC_010473.1 442031 443251 R fosmidomycin efflux system complement(442031..443251) Escherichia coli str. K-12 substr. DH10B 6059782 YP_001729385.1 CDS ushA NC_010473.1 443469 445121 D catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 443469..445121 Escherichia coli str. K-12 substr. DH10B 6059784 YP_001729386.1 CDS ybaK NC_010473.1 445158 445637 R hypothetical protein complement(445158..445637) Escherichia coli str. K-12 substr. DH10B 6062380 YP_001729387.1 CDS ybaP NC_010473.1 445841 446635 R hypothetical protein complement(445841..446635) Escherichia coli str. K-12 substr. DH10B 6058803 YP_001729388.1 CDS ybaQ NC_010473.1 446773 447114 D DNA-binding transcriptional regulator 446773..447114 Escherichia coli str. K-12 substr. DH10B 6059796 YP_001729389.1 CDS copA NC_010473.1 447430 449934 R copper exporting ATPase complement(447430..449934) Escherichia coli str. K-12 substr. DH10B 6059797 YP_001729390.1 CDS ybaS NC_010473.1 450196 451128 D catalyzes the formation of glutamate from glutamine; glutaminase 450196..451128 Escherichia coli str. K-12 substr. DH10B 6059798 YP_001729391.1 CDS ybaT NC_010473.1 451131 452423 D transporter 451131..452423 Escherichia coli str. K-12 substr. DH10B 6059799 YP_001729392.1 CDS cueR NC_010473.1 452548 452955 D activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 452548..452955 Escherichia coli str. K-12 substr. DH10B 6059803 YP_001729393.1 CDS ybbJ NC_010473.1 452956 453411 R inner membrane protein complement(452956..453411) Escherichia coli str. K-12 substr. DH10B 6059805 YP_001729394.1 CDS qmcA NC_010473.1 453411 454328 R protease, membrane anchored complement(453411..454328) Escherichia coli str. K-12 substr. DH10B 6059811 YP_001729395.1 CDS ybbL NC_010473.1 454474 455151 D putative ABC transporter ATP-binding protein YbbL 454474..455151 Escherichia coli str. K-12 substr. DH10B 6059812 YP_001729396.1 CDS ybbM NC_010473.1 455138 455917 D inner membrane protein 455138..455917 Escherichia coli str. K-12 substr. DH10B 6059813 YP_001729397.1 CDS ybbN NC_010473.1 455980 456834 R thioredoxin domain-containing protein complement(455980..456834) Escherichia coli str. K-12 substr. DH10B 6059818 YP_001729398.1 CDS ybbO NC_010473.1 456895 457704 R short chain dehydrogenase complement(456895..457704) Escherichia coli str. K-12 substr. DH10B 6059819 YP_001729399.1 CDS tesA NC_010473.1 457694 458320 R multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 complement(457694..458320) Escherichia coli str. K-12 substr. DH10B 6059820 YP_001729400.1 CDS ybbA NC_010473.1 458288 458974 D putative ABC transporter ATP-binding protein YbbA 458288..458974 Escherichia coli str. K-12 substr. DH10B 6059822 YP_001729401.1 CDS ybbP NC_010473.1 458971 461385 D inner membrane protein 458971..461385 Escherichia coli str. K-12 substr. DH10B 6059824 YP_001729402.1 CDS rhsD NC_010473.1 461816 466096 D rhsD element protein 461816..466096 Escherichia coli str. K-12 substr. DH10B 6059617 YP_001729403.1 CDS ybbC NC_010473.1 466136 466504 D hypothetical protein 466136..466504 Escherichia coli str. K-12 substr. DH10B 6059619 YP_001729404.1 CDS ylbH NC_010473.1 466504 467214 D protein, rhs-like protein 466504..467214 Escherichia coli str. K-12 substr. DH10B 6059624 YP_001729405.1 CDS ylbG NC_010473.1 468200 468571 R DNA-binding transcriptional regulator complement(468200..468571) Escherichia coli str. K-12 substr. DH10B 6059334 YP_001729406.1 CDS ybbB NC_010473.1 468687 469781 R catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase complement(468687..469781) Escherichia coli str. K-12 substr. DH10B 6059628 YP_001729407.1 CDS allS NC_010473.1 469850 470776 R activator of the allDC-ylbA operon involved in allantoin utilization; DNA-binding transcriptional activator AllS complement(469850..470776) Escherichia coli str. K-12 substr. DH10B 6059630 YP_001729408.1 CDS allA NC_010473.1 471006 471488 D catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 471006..471488 Escherichia coli str. K-12 substr. DH10B 6059827 YP_001729409.1 CDS allR NC_010473.1 471566 472381 D regulates operons involved in the utilization of allantoin; DNA-binding transcriptional repressor AllR 471566..472381 Escherichia coli str. K-12 substr. DH10B 6059851 YP_001729410.1 CDS gcl NC_010473.1 472471 474252 D catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate; glyoxylate carboligase 472471..474252 Escherichia coli str. K-12 substr. DH10B 6059868 YP_001729411.1 CDS hyi NC_010473.1 474265 475041 D hydroxypyruvate isomerase 474265..475041 Escherichia coli str. K-12 substr. DH10B 6059884 YP_001729412.1 CDS glxR NC_010473.1 475141 476019 D tartronate semialdehyde reductase, NADH-dependent 475141..476019 Escherichia coli str. K-12 substr. DH10B 6059888 YP_001729413.1 CDS ybbV NC_010473.1 476051 476329 D hypothetical protein 476051..476329 Escherichia coli str. K-12 substr. DH10B 6059894 YP_001729414.1 CDS ybbW NC_010473.1 476188 477642 D allantoin permease 476188..477642 Escherichia coli str. K-12 substr. DH10B 6059898 YP_001729415.1 CDS allB NC_010473.1 477702 479063 D Plays a crucial role on both purine and pyrimidine metabolism; allantoinase 477702..479063 Escherichia coli str. K-12 substr. DH10B 6059904 YP_001729416.1 CDS ybbY NC_010473.1 479120 480421 D putative purine permease YbbY 479120..480421 Escherichia coli str. K-12 substr. DH10B 6059907 YP_001729417.1 CDS glxK NC_010473.1 480443 481588 D glycerate kinase 480443..481588 Escherichia coli str. K-12 substr. DH10B 6059931 YP_001729418.1 CDS ylbA NC_010473.1 481816 482601 R hypothetical protein complement(481816..482601) Escherichia coli str. K-12 substr. DH10B 6059936 YP_001729419.1 CDS allC NC_010473.1 482612 483847 R allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase complement(482612..483847) Escherichia coli str. K-12 substr. DH10B 6059940 YP_001729420.1 CDS allD NC_010473.1 483869 484918 R ureidoglycolate dehydrogenase complement(483869..484918) Escherichia coli str. K-12 substr. DH10B 6059947 YP_001729421.1 CDS fdrA NC_010473.1 485235 486902 D multicopy suppressor of dominant negative ftsH mutations; membrane protein FdrA 485235..486902 Escherichia coli str. K-12 substr. DH10B 6059980 YP_001729422.1 CDS ylbE NC_010473.1 486912 488171 D DH10B lacks the frameshift in codon 85 that disrupts ylbE in both MG1655 and W3110; hypothetical protein 486912..488171 Escherichia coli str. K-12 substr. DH10B 6060012 YP_001729423.1 CDS ylbF NC_010473.1 488182 488997 D hypothetical protein 488182..488997 Escherichia coli str. K-12 substr. DH10B 6058653 YP_001729424.1 CDS ybcF NC_010473.1 488994 489887 D carbamate kinase 488994..489887 Escherichia coli str. K-12 substr. DH10B 6060016 YP_001729425.1 CDS purK NC_010473.1 490082 491149 R With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit complement(490082..491149) Escherichia coli str. K-12 substr. DH10B 6060032 YP_001729426.1 CDS purE NC_010473.1 491146 491655 R N5-carboxyaminoimidazole ribonucleotide mutase complement(491146..491655) Escherichia coli str. K-12 substr. DH10B 6060049 YP_001729427.1 CDS lpxH NC_010473.1 491773 492495 R catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase complement(491773..492495) Escherichia coli str. K-12 substr. DH10B 6060059 YP_001729428.1 CDS ppiB NC_010473.1 492498 492992 R peptidyl-prolyl cis-trans isomerase B complement(492498..492992) Escherichia coli str. K-12 substr. DH10B 6060071 YP_001729429.1 CDS cysS NC_010473.1 493166 494551 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 493166..494551 Escherichia coli str. K-12 substr. DH10B 6058949 YP_001729430.1 CDS ybcI NC_010473.1 494587 495108 R inner membrane protein complement(494587..495108) Escherichia coli str. K-12 substr. DH10B 6060076 YP_001729431.1 CDS ybcJ NC_010473.1 495216 495428 R hypothetical protein complement(495216..495428) Escherichia coli str. K-12 substr. DH10B 6060077 YP_001729432.1 CDS folD NC_010473.1 495430 496296 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(495430..496296) Escherichia coli str. K-12 substr. DH10B 6060087 YP_001729433.1 CDS sfmA NC_010473.1 496767 497309 D fimbrial-like adhesin protein 496767..497309 Escherichia coli str. K-12 substr. DH10B 6060090 YP_001729434.1 CDS sfmC NC_010473.1 497529 498221 D pilin chaperone, periplasmic 497529..498221 Escherichia coli str. K-12 substr. DH10B 6060101 YP_001729435.1 CDS sfmD NC_010473.1 498252 500855 D outer membrane export usher protein 498252..500855 Escherichia coli str. K-12 substr. DH10B 6060103 YP_001729436.1 CDS sfmH NC_010473.1 500891 501874 D fimbrial-like adhesin protein 500891..501874 Escherichia coli str. K-12 substr. DH10B 6060110 YP_001729437.1 CDS sfmF NC_010473.1 501885 502400 D putative fimbrial protein 501885..502400 Escherichia coli str. K-12 substr. DH10B 6060117 YP_001729438.1 CDS fimZ NC_010473.1 502403 503035 R activates the production of the major fimbrae protein FimA; transcriptional regulator FimZ complement(502403..503035) Escherichia coli str. K-12 substr. DH10B 6060120 YP_001729439.1 CDS intD NC_010473.1 503370 504533 R DLP12 prophage; integrase complement(503370..504533) Escherichia coli str. K-12 substr. DH10B 6058724 YP_001729440.1 CDS ybcC NC_010473.1 504653 504916 R DLP12 prophage; exonuclease complement(504653..504916) Escherichia coli str. K-12 substr. DH10B 6060122 YP_001729441.1 CDS insE-3 NC_010473.1 505388 505696 D DLP12 prophage; IS3 element protein InsE 505388..505696 Escherichia coli str. K-12 substr. DH10B 6058968 YP_001729442.1 CDS insF-3 NC_010473.1 505693 506559 D DLP12 prophage; IS3 element protein InsF 505693..506559 Escherichia coli str. K-12 substr. DH10B 6060137 YP_001729443.1 CDS renD NC_010473.1 506617 506802 D DLP12 prophage; hypothetical protein 506617..506802 Escherichia coli str. K-12 substr. DH10B 6060175 YP_001729444.1 CDS emrE NC_010473.1 506870 507202 D member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation; multidrug efflux protein 506870..507202 Escherichia coli str. K-12 substr. DH10B 6060189 YP_001729445.1 CDS ybcK NC_010473.1 507457 508983 D DLP12 prophage; recombinase 507457..508983 Escherichia coli str. K-12 substr. DH10B 6060193 YP_001729446.1 CDS ybcL NC_010473.1 509448 509999 D DLP12 prophage; similar to PEBP/RK1P protein family in eukaryotes that inhibits MEK phosphorylation by Raf-1; crystal structure suggests similar properties but exact function is unknown; putative kinase inhibitor 509448..509999 Escherichia coli str. K-12 substr. DH10B 6060200 YP_001729447.1 CDS ybcM NC_010473.1 510009 510806 D DLP12 prophage; DNA-binding transcriptional regulator 510009..510806 Escherichia coli str. K-12 substr. DH10B 6060206 YP_001729448.1 CDS ybcN NC_010473.1 511021 511476 D DLP12 prophage; hypothetical protein 511021..511476 Escherichia coli str. K-12 substr. DH10B 6060210 YP_001729449.1 CDS ninE NC_010473.1 511476 511646 D DLP12 prophage; conserved protein similar to phage 82 and lambda proteins; prophage protein NinE 511476..511646 Escherichia coli str. K-12 substr. DH10B 6060221 YP_001729450.1 CDS ybcO NC_010473.1 511639 511929 D DLP12 prophage; hypothetical protein 511639..511929 Escherichia coli str. K-12 substr. DH10B 6062415 YP_001729451.1 CDS rusA NC_010473.1 511926 512288 D DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 511926..512288 Escherichia coli str. K-12 substr. DH10B 6060232 YP_001729452.1 CDS ylcG NC_010473.1 512285 512425 D DLP12 prophage; hypothetical protein 512285..512425 Escherichia coli str. K-12 substr. DH10B 6060238 YP_001729453.1 CDS ybcQ NC_010473.1 512511 512894 D DLP12 prophage; antitermination protein 512511..512894 Escherichia coli str. K-12 substr. DH10B 6060239 YP_001729454.1 CDS insH-2 NC_010473.1 513292 514308 R DLP12 prophage; IS5 transposase and trans-activator complement(513292..514308) Escherichia coli str. K-12 substr. DH10B 6059499 YP_001729455.1 CDS essD NC_010473.1 515953 516168 D DLP12 prophage; phage lysis protein 515953..516168 Escherichia coli str. K-12 substr. DH10B 6060252 YP_001729456.1 CDS ybcS NC_010473.1 516168 516665 D DLP12 prophage; lysozyme 516168..516665 Escherichia coli str. K-12 substr. DH10B 6060258 YP_001729457.1 CDS rzpD NC_010473.1 516662 517123 D DLP12 prophage; murein endopeptidase 516662..517123 Escherichia coli str. K-12 substr. DH10B 6060259 YP_001729458.1 CDS rzoD NC_010473.1 516882 517064 D DLP12 prophage; lipoprotein 516882..517064 Escherichia coli str. K-12 substr. DH10B 6060266 YP_001729459.1 CDS borD NC_010473.1 517155 517448 R DLP12 prophage; lipoprotein complement(517155..517448) Escherichia coli str. K-12 substr. DH10B 6060273 YP_001729460.1 CDS ybcV NC_010473.1 517739 518149 R DLP12 prophage; hypothetical protein complement(517739..518149) Escherichia coli str. K-12 substr. DH10B 6060282 YP_001729461.1 CDS ybcW NC_010473.1 518435 518641 D DLP12 prophage; hypothetical protein 518435..518641 Escherichia coli str. K-12 substr. DH10B 6060296 YP_001729462.1 CDS nohB NC_010473.1 519389 519934 D DLP12 prophage; DNA packaging protein 519389..519934 Escherichia coli str. K-12 substr. DH10B 6060303 YP_001729463.1 CDS appY NC_010473.1 522236 522985 D DLP12 prophage; DNA-binding transcriptional activator 522236..522985 Escherichia coli str. K-12 substr. DH10B 6060852 YP_001729464.1 CDS ompT NC_010473.1 523235 524188 R outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease complement(523235..524188) Escherichia coli str. K-12 substr. DH10B 6060305 YP_001729465.1 CDS envY NC_010473.1 524702 525463 R DNA-binding transcriptional activator of porin biosynthesis complement(524702..525463) Escherichia coli str. K-12 substr. DH10B 6060306 YP_001729466.1 CDS ybcH NC_010473.1 525646 526536 R hypothetical protein complement(525646..526536) Escherichia coli str. K-12 substr. DH10B 6059964 YP_001729467.1 CDS nfrA NC_010473.1 526537 529509 R bacteriophage N4 receptor, outer membrane subunit complement(526537..529509) Escherichia coli str. K-12 substr. DH10B 6060307 YP_001729468.1 CDS nfrB NC_010473.1 529496 531733 R bacteriophage N4 adsorption protein B complement(529496..531733) Escherichia coli str. K-12 substr. DH10B 6060321 YP_001729469.1 CDS cusS NC_010473.1 531883 533325 R sensor kinase CusS complement(531883..533325) Escherichia coli str. K-12 substr. DH10B 6060324 YP_001729470.1 CDS cusR NC_010473.1 533315 533998 R response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR complement(533315..533998) Escherichia coli str. K-12 substr. DH10B 6060325 YP_001729471.1 CDS cusC NC_010473.1 534155 535528 D with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 534155..535528 Escherichia coli str. K-12 substr. DH10B 6060327 YP_001729472.1 CDS cusF NC_010473.1 535686 536018 D copper-binding protein 535686..536018 Escherichia coli str. K-12 substr. DH10B 6060329 YP_001729473.1 CDS cusB NC_010473.1 536034 537257 D with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 536034..537257 Escherichia coli str. K-12 substr. DH10B 6060339 YP_001729474.1 CDS cusA NC_010473.1 537269 540412 D copper/silver efflux system, membrane component 537269..540412 Escherichia coli str. K-12 substr. DH10B 6060345 YP_001729475.1 CDS pheP NC_010473.1 540514 541890 D phenylalanine transporter 540514..541890 Escherichia coli str. K-12 substr. DH10B 6060346 YP_001729476.1 CDS ybdG NC_010473.1 541971 543218 R mechanosensitive channel complement(541971..543218) Escherichia coli str. K-12 substr. DH10B 6060356 YP_001729477.1 CDS nfnB NC_010473.1 543326 543979 R catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase complement(543326..543979) Escherichia coli str. K-12 substr. DH10B 6060362 YP_001729478.1 CDS ybdF NC_010473.1 544073 544441 R hypothetical protein complement(544073..544441) Escherichia coli str. K-12 substr. DH10B 6060370 YP_001729479.1 CDS ybdJ NC_010473.1 544506 544754 R inner membrane protein complement(544506..544754) Escherichia coli str. K-12 substr. DH10B 6060382 YP_001729480.1 CDS ybdK NC_010473.1 544820 545938 R ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase complement(544820..545938) Escherichia coli str. K-12 substr. DH10B 6060383 YP_001729481.1 CDS hokE NC_010473.1 546391 546543 D toxic polypeptide, small 546391..546543 Escherichia coli str. K-12 substr. DH10B 6060387 YP_001729482.1 CDS insL-2 NC_010473.1 546620 547732 D IS186/IS421 transposase 546620..547732 Escherichia coli str. K-12 substr. DH10B 6060394 YP_001729483.1 CDS entD NC_010473.1 548014 548643 R phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex complement(548014..548643) Escherichia coli str. K-12 substr. DH10B 6060408 YP_001729484.1 CDS fepA NC_010473.1 548809 551049 R Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA complement(548809..551049) Escherichia coli str. K-12 substr. DH10B 6060409 YP_001729485.1 CDS fes NC_010473.1 551370 552494 D enterobactin/ferric enterobactin esterase 551370..552494 Escherichia coli str. K-12 substr. DH10B 6060423 YP_001729486.1 CDS ybdZ NC_010473.1 552497 552715 D hypothetical protein 552497..552715 Escherichia coli str. K-12 substr. DH10B 6060424 YP_001729487.1 CDS entF NC_010473.1 552712 556593 D with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 552712..556593 Escherichia coli str. K-12 substr. DH10B 6060427 YP_001729488.1 CDS fepE NC_010473.1 556809 557942 D part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 556809..557942 Escherichia coli str. K-12 substr. DH10B 6060429 YP_001729489.1 CDS fepC NC_010473.1 557939 558754 R with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein complement(557939..558754) Escherichia coli str. K-12 substr. DH10B 6060434 YP_001729490.1 CDS fepG NC_010473.1 558751 559743 R with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease complement(558751..559743) Escherichia coli str. K-12 substr. DH10B 6060454 YP_001729491.1 CDS fepD NC_010473.1 559740 560744 R with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein complement(559740..560744) Escherichia coli str. K-12 substr. DH10B 6060458 YP_001729492.1 CDS entS NC_010473.1 560855 562105 D protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 560855..562105 Escherichia coli str. K-12 substr. DH10B 6058761 YP_001729493.1 CDS fepB NC_010473.1 562109 563065 R with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein complement(562109..563065) Escherichia coli str. K-12 substr. DH10B 6059043 YP_001729494.1 CDS entC NC_010473.1 563440 564615 D isochorismate synthase 1 563440..564615 Escherichia coli str. K-12 substr. DH10B 6060467 YP_001729495.1 CDS entE NC_010473.1 564625 566235 D bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 564625..566235 Escherichia coli str. K-12 substr. DH10B 6060494 YP_001729496.1 CDS entB NC_010473.1 566249 567106 D isochorismatase 566249..567106 Escherichia coli str. K-12 substr. DH10B 6060506 YP_001729497.1 CDS entA NC_010473.1 567106 567852 D catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 567106..567852 Escherichia coli str. K-12 substr. DH10B 6060507 YP_001729498.1 CDS ybdB NC_010473.1 567855 568268 D hypothetical protein 567855..568268 Escherichia coli str. K-12 substr. DH10B 6060512 YP_001729499.1 CDS cstA NC_010473.1 568449 570554 D carbon starvation protein 568449..570554 Escherichia coli str. K-12 substr. DH10B 6060515 YP_001729500.1 CDS ybdD NC_010473.1 570737 570934 D hypothetical protein 570737..570934 Escherichia coli str. K-12 substr. DH10B 6060527 YP_001729501.1 CDS ybdH NC_010473.1 570944 572032 R member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein complement(570944..572032) Escherichia coli str. K-12 substr. DH10B 6060528 YP_001729502.1 CDS ybdL NC_010473.1 572141 573301 D catalyzes the transfer of an amino moiety; putative aminotransferase 572141..573301 Escherichia coli str. K-12 substr. DH10B 6060530 YP_001729503.1 CDS ybdM NC_010473.1 573302 573931 R hypothetical protein complement(573302..573931) Escherichia coli str. K-12 substr. DH10B 6060543 YP_001729504.1 CDS ybdN NC_010473.1 573904 575124 R hypothetical protein complement(573904..575124) Escherichia coli str. K-12 substr. DH10B 6058990 YP_001729505.1 CDS ybdO NC_010473.1 575271 576173 R DNA-binding transcriptional regulator complement(575271..576173) Escherichia coli str. K-12 substr. DH10B 6060548 YP_001729506.1 CDS dsbG NC_010473.1 576382 577128 R Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase complement(576382..577128) Escherichia coli str. K-12 substr. DH10B 6060576 YP_001729507.1 CDS ahpC NC_010473.1 577500 578063 D with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase subunit C 577500..578063 Escherichia coli str. K-12 substr. DH10B 6060578 YP_001729508.1 CDS ahpF NC_010473.1 578308 579873 D alkyl hydroperoxide reductase, F52a subunit, FAD/NAD(P)-binding 578308..579873 Escherichia coli str. K-12 substr. DH10B 6060587 YP_001729509.1 CDS uspG NC_010473.1 579994 580422 R universal stress protein UP12 complement(579994..580422) Escherichia coli str. K-12 substr. DH10B 6060594 YP_001729510.1 CDS ybdR NC_010473.1 580643 581881 D oxidoreductase, Zn-dependent and NAD(P)-binding 580643..581881 Escherichia coli str. K-12 substr. DH10B 6060595 YP_001729511.1 CDS rnk NC_010473.1 582112 582522 R Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator complement(582112..582522) Escherichia coli str. K-12 substr. DH10B 6060599 YP_001729512.1 CDS rna NC_010473.1 582752 583558 R ribonuclease I complement(582752..583558) Escherichia coli str. K-12 substr. DH10B 6060604 YP_001729513.1 CDS citT NC_010473.1 583672 585135 R citrate:succinate antiporter complement(583672..585135) Escherichia coli str. K-12 substr. DH10B 6060607 YP_001729514.1 CDS citG NC_010473.1 585186 586064 R catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase complement(585186..586064) Escherichia coli str. K-12 substr. DH10B 6060609 YP_001729515.1 CDS citX NC_010473.1 586039 586590 R 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase complement(586039..586590) Escherichia coli str. K-12 substr. DH10B 6060615 YP_001729516.1 CDS citF NC_010473.1 586594 588126 R citrate lyase, citrate-ACP transferase (alpha) subunit complement(586594..588126) Escherichia coli str. K-12 substr. DH10B 6060618 YP_001729517.1 CDS citE NC_010473.1 588137 589045 R citrate lyase, citryl-ACP lyase (beta) subunit complement(588137..589045) Escherichia coli str. K-12 substr. DH10B 6060635 YP_001729518.1 CDS citD NC_010473.1 589042 589338 R acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma complement(589042..589338) Escherichia coli str. K-12 substr. DH10B 6060637 YP_001729519.1 CDS citC NC_010473.1 589353 590411 R citrate lyase synthetase complement(589353..590411) Escherichia coli str. K-12 substr. DH10B 6060648 YP_001729520.1 CDS citA NC_010473.1 590790 592448 D sensory histidine kinase in two-component regulatory system with citB 590790..592448 Escherichia coli str. K-12 substr. DH10B 6060680 YP_001729521.1 CDS dpiA NC_010473.1 592417 593097 D regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 592417..593097 Escherichia coli str. K-12 substr. DH10B 6060684 YP_001729522.1 CDS dcuC NC_010473.1 593138 594523 R responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC complement(593138..594523) Escherichia coli str. K-12 substr. DH10B 6060693 YP_001729523.1 CDS pagP NC_010473.1 595112 595672 D catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 595112..595672 Escherichia coli str. K-12 substr. DH10B 6060696 YP_001729524.1 CDS cspE NC_010473.1 595847 596056 D member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 595847..596056 Escherichia coli str. K-12 substr. DH10B 6060698 YP_001729525.1 CDS crcB NC_010473.1 596110 596493 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(596110..596493) Escherichia coli str. K-12 substr. DH10B 6058649 YP_001729526.1 CDS tatE NC_010473.1 597502 597705 D TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein E 597502..597705 Escherichia coli str. K-12 substr. DH10B 6061792 YP_001729527.1 CDS lipA NC_010473.1 597806 598771 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(597806..598771) Escherichia coli str. K-12 substr. DH10B 6060715 YP_001729528.1 CDS ybeF NC_010473.1 598980 599933 R putative DNA-binding transcriptional regulator complement(598980..599933) Escherichia coli str. K-12 substr. DH10B 6060717 YP_001729529.1 CDS lipB NC_010473.1 600192 600833 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(600192..600833) Escherichia coli str. K-12 substr. DH10B 6060719 YP_001729530.1 CDS ybeD NC_010473.1 600934 601197 R hypothetical protein complement(600934..601197) Escherichia coli str. K-12 substr. DH10B 6060731 YP_001729531.1 CDS dacA NC_010473.1 601307 602518 R penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase complement(601307..602518) Escherichia coli str. K-12 substr. DH10B 6062416 YP_001729532.1 CDS rlpA NC_010473.1 602657 603745 R rare lipoprotein A complement(602657..603745) Escherichia coli str. K-12 substr. DH10B 6059374 YP_001729533.1 CDS mrdB NC_010473.1 603756 604868 R cell wall shape-determining protein complement(603756..604868) Escherichia coli str. K-12 substr. DH10B 6060451 YP_001729534.1 CDS mrdA NC_010473.1 604871 606772 R penicillin-binding protein 2 complement(604871..606772) Escherichia coli str. K-12 substr. DH10B 6058741 YP_001729535.1 CDS ybeA NC_010473.1 606803 607270 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(606803..607270) Escherichia coli str. K-12 substr. DH10B 6058885 YP_001729536.1 CDS ybeB NC_010473.1 607274 607591 R hypothetical protein complement(607274..607591) Escherichia coli str. K-12 substr. DH10B 6058983 YP_001729537.1 CDS cobC NC_010473.1 607851 608462 R alpha-ribazole-5'-phosphate phosphatase complement(607851..608462) Escherichia coli str. K-12 substr. DH10B 6059060 YP_001729538.1 CDS nadD NC_010473.1 608486 609127 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase complement(608486..609127) Escherichia coli str. K-12 substr. DH10B 6059069 YP_001729539.1 CDS holA NC_010473.1 609129 610160 R required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta complement(609129..610160) Escherichia coli str. K-12 substr. DH10B 6059100 YP_001729540.1 CDS rlpB NC_010473.1 610160 610741 R rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB complement(610160..610741) Escherichia coli str. K-12 substr. DH10B 6059197 YP_001729541.1 CDS leuS NC_010473.1 610756 613338 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(610756..613338) Escherichia coli str. K-12 substr. DH10B 6059747 YP_001729542.1 CDS ybeL NC_010473.1 613573 614055 D hypothetical protein 613573..614055 Escherichia coli str. K-12 substr. DH10B 6060062 YP_001729543.1 CDS ybeQ NC_010473.1 614125 615102 R hypothetical protein complement(614125..615102) Escherichia coli str. K-12 substr. DH10B 6060019 YP_001729544.1 CDS ybeR NC_010473.1 615266 615973 D hypothetical protein 615266..615973 Escherichia coli str. K-12 substr. DH10B 6060489 YP_001729545.1 CDS djlB NC_010473.1 615970 617397 D chaperone 615970..617397 Escherichia coli str. K-12 substr. DH10B 6059207 YP_001729546.1 CDS ybeT NC_010473.1 617407 617961 R outer membrane protein complement(617407..617961) Escherichia coli str. K-12 substr. DH10B 6058995 YP_001729547.1 CDS ybeU NC_010473.1 618063 618770 D tRNA ligase 618063..618770 Escherichia coli str. K-12 substr. DH10B 6058621 YP_001729548.1 CDS djlC NC_010473.1 618767 620218 D Hsc56 co-chaperone of HscC 618767..620218 Escherichia coli str. K-12 substr. DH10B 6059606 YP_001729549.1 CDS hscC NC_010473.1 620278 621948 R Hsp70 family chaperone Hsc62, binds to RpoD and inhibits transcription complement(620278..621948) Escherichia coli str. K-12 substr. DH10B 6060007 YP_001729550.1 CDS rihA NC_010473.1 622032 622967 R Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 complement(622032..622967) Escherichia coli str. K-12 substr. DH10B 6058609 YP_001729551.1 CDS gltL NC_010473.1 623085 623810 R glutamate/aspartate ABC transporter ATP-binding protein complement(623085..623810) Escherichia coli str. K-12 substr. DH10B 6061849 YP_001729552.1 CDS gltK NC_010473.1 623810 624484 R glutamate/aspartate ABC transporter membrane protein complement(623810..624484) Escherichia coli str. K-12 substr. DH10B 6061850 YP_001729553.1 CDS gltJ NC_010473.1 624484 625224 R glutamate/aspartate ABC transporter membrane protein complement(624484..625224) Escherichia coli str. K-12 substr. DH10B 6061843 YP_001729554.1 CDS gltI NC_010473.1 625394 626302 R glutamate and aspartate transporter subunit complement(625394..626302) Escherichia coli str. K-12 substr. DH10B 6061847 YP_001729555.1 CDS insH-3 NC_010473.1 626552 627568 R IS5 transposase and trans-activator complement(626552..627568) Escherichia coli str. K-12 substr. DH10B 6061853 YP_001729556.1 CDS essD NC_010473.1 629213 629428 D DLP12 prophage; phage lysis protein 629213..629428 Escherichia coli str. K-12 substr. DH10B 6061756 YP_001729557.1 CDS ybcS NC_010473.1 629428 629925 D DLP12 prophage; lysozyme 629428..629925 Escherichia coli str. K-12 substr. DH10B 6061840 YP_001729558.1 CDS rzpD NC_010473.1 629922 630383 D DLP12 prophage; murein endopeptidase 629922..630383 Escherichia coli str. K-12 substr. DH10B 6061828 YP_001729559.1 CDS rzoD NC_010473.1 630142 630324 D DLP12 prophage; lipoprotein 630142..630324 Escherichia coli str. K-12 substr. DH10B 6061831 YP_001729560.1 CDS borD NC_010473.1 630415 630708 R DLP12 prophage; lipoprotein complement(630415..630708) Escherichia coli str. K-12 substr. DH10B 6061841 YP_001729561.1 CDS ybcV NC_010473.1 630999 631409 R DLP12 prophage; hypothetical protein complement(630999..631409) Escherichia coli str. K-12 substr. DH10B 6061822 YP_001729562.1 CDS ybcW NC_010473.1 631695 631901 D DLP12 prophage; hypothetical protein 631695..631901 Escherichia coli str. K-12 substr. DH10B 6061818 YP_001729563.1 CDS nohB NC_010473.1 632649 633194 D DLP12 prophage; DNA packaging protein 632649..633194 Escherichia coli str. K-12 substr. DH10B 6061807 YP_001729564.1 CDS appY NC_010473.1 635496 636245 D DLP12 prophage; DNA-binding transcriptional activator 635496..636245 Escherichia coli str. K-12 substr. DH10B 6061507 YP_001729565.1 CDS ompT NC_010473.1 636495 637448 R outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease complement(636495..637448) Escherichia coli str. K-12 substr. DH10B 6061795 YP_001729566.1 CDS envY NC_010473.1 637962 638723 R DNA-binding transcriptional activator of porin biosynthesis complement(637962..638723) Escherichia coli str. K-12 substr. DH10B 6061797 YP_001729567.1 CDS ybcH NC_010473.1 638906 639796 R hypothetical protein complement(638906..639796) Escherichia coli str. K-12 substr. DH10B 6061784 YP_001729568.1 CDS nfrA NC_010473.1 639797 642769 R bacteriophage N4 receptor, outer membrane subunit complement(639797..642769) Escherichia coli str. K-12 substr. DH10B 6061778 YP_001729569.1 CDS nfrB NC_010473.1 642756 644993 R bacteriophage N4 adsorption protein B complement(642756..644993) Escherichia coli str. K-12 substr. DH10B 6061781 YP_001729570.1 CDS cusS NC_010473.1 645143 646585 R sensor kinase CusS complement(645143..646585) Escherichia coli str. K-12 substr. DH10B 6061773 YP_001729571.1 CDS cusR NC_010473.1 646575 647258 R response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR complement(646575..647258) Escherichia coli str. K-12 substr. DH10B 6061783 YP_001729572.1 CDS cusC NC_010473.1 647415 648788 D with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 647415..648788 Escherichia coli str. K-12 substr. DH10B 6061765 YP_001729573.1 CDS cusF NC_010473.1 648946 649278 D copper-binding protein 648946..649278 Escherichia coli str. K-12 substr. DH10B 6061768 YP_001729574.1 CDS cusB NC_010473.1 649294 650517 D with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 649294..650517 Escherichia coli str. K-12 substr. DH10B 6061763 YP_001729575.1 CDS cusA NC_010473.1 650529 653672 D copper/silver efflux system, membrane component 650529..653672 Escherichia coli str. K-12 substr. DH10B 6061771 YP_001729576.1 CDS pheP NC_010473.1 653774 655150 D phenylalanine transporter 653774..655150 Escherichia coli str. K-12 substr. DH10B 6061754 YP_001729577.1 CDS ybdG NC_010473.1 655231 656478 R mechanosensitive channel complement(655231..656478) Escherichia coli str. K-12 substr. DH10B 6061758 YP_001729578.1 CDS nfnB NC_010473.1 656586 657239 R catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase complement(656586..657239) Escherichia coli str. K-12 substr. DH10B 6061753 YP_001729579.1 CDS ybdF NC_010473.1 657333 657701 R hypothetical protein complement(657333..657701) Escherichia coli str. K-12 substr. DH10B 6061761 YP_001729580.1 CDS ybdJ NC_010473.1 657766 658014 R inner membrane protein complement(657766..658014) Escherichia coli str. K-12 substr. DH10B 6061815 YP_001729581.1 CDS ybdK NC_010473.1 658080 659198 R ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase complement(658080..659198) Escherichia coli str. K-12 substr. DH10B 6061802 YP_001729582.1 CDS hokE NC_010473.1 659651 659803 D toxic polypeptide, small 659651..659803 Escherichia coli str. K-12 substr. DH10B 6061799 YP_001729583.1 CDS insL-2 NC_010473.1 659880 660992 D IS186/IS421 transposase 659880..660992 Escherichia coli str. K-12 substr. DH10B 6061788 YP_001729584.1 CDS entD NC_010473.1 661274 661903 R phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex complement(661274..661903) Escherichia coli str. K-12 substr. DH10B 6061744 YP_001729585.1 CDS fepA NC_010473.1 662069 664309 R Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA complement(662069..664309) Escherichia coli str. K-12 substr. DH10B 6061746 YP_001729586.1 CDS fes NC_010473.1 664630 665754 D enterobactin/ferric enterobactin esterase 664630..665754 Escherichia coli str. K-12 substr. DH10B 6061736 YP_001729587.1 CDS ybdZ NC_010473.1 665757 665975 D hypothetical protein 665757..665975 Escherichia coli str. K-12 substr. DH10B 6061740 YP_001729588.1 CDS entF NC_010473.1 665972 669853 D with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 665972..669853 Escherichia coli str. K-12 substr. DH10B 6061748 YP_001729589.1 CDS fepE NC_010473.1 670069 671202 D part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 670069..671202 Escherichia coli str. K-12 substr. DH10B 6061728 YP_001729590.1 CDS fepC NC_010473.1 671199 672014 R with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein complement(671199..672014) Escherichia coli str. K-12 substr. DH10B 6061712 YP_001729591.1 CDS fepG NC_010473.1 672011 673003 R with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease complement(672011..673003) Escherichia coli str. K-12 substr. DH10B 6061713 YP_001729592.1 CDS fepD NC_010473.1 673000 674004 R with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein complement(673000..674004) Escherichia coli str. K-12 substr. DH10B 6061708 YP_001729593.1 CDS entS NC_010473.1 674115 675365 D protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 674115..675365 Escherichia coli str. K-12 substr. DH10B 6061696 YP_001729594.1 CDS fepB NC_010473.1 675369 676325 R with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein complement(675369..676325) Escherichia coli str. K-12 substr. DH10B 6061699 YP_001729595.1 CDS entC NC_010473.1 676700 677875 D isochorismate synthase 1 676700..677875 Escherichia coli str. K-12 substr. DH10B 6061682 YP_001729596.1 CDS entE NC_010473.1 677885 679495 D bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 677885..679495 Escherichia coli str. K-12 substr. DH10B 6061703 YP_001729597.1 CDS entB NC_010473.1 679509 680366 D isochorismatase 679509..680366 Escherichia coli str. K-12 substr. DH10B 6061669 YP_001729598.1 CDS entA NC_010473.1 680366 681112 D catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 680366..681112 Escherichia coli str. K-12 substr. DH10B 6061677 YP_001729599.1 CDS ybdB NC_010473.1 681115 681528 D hypothetical protein 681115..681528 Escherichia coli str. K-12 substr. DH10B 6061667 YP_001729600.1 CDS cstA NC_010473.1 681709 683814 D carbon starvation protein 681709..683814 Escherichia coli str. K-12 substr. DH10B 6061679 YP_001729601.1 CDS ybdD NC_010473.1 683997 684194 D hypothetical protein 683997..684194 Escherichia coli str. K-12 substr. DH10B 6061715 YP_001729602.1 CDS ybdH NC_010473.1 684204 685292 R member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein complement(684204..685292) Escherichia coli str. K-12 substr. DH10B 6061709 YP_001729603.1 CDS ybdL NC_010473.1 685401 686561 D catalyzes the transfer of an amino moiety; putative aminotransferase 685401..686561 Escherichia coli str. K-12 substr. DH10B 6061661 YP_001729604.1 CDS ybdM NC_010473.1 686562 687191 R hypothetical protein complement(686562..687191) Escherichia coli str. K-12 substr. DH10B 6061663 YP_001729605.1 CDS ybdN NC_010473.1 687164 688384 R hypothetical protein complement(687164..688384) Escherichia coli str. K-12 substr. DH10B 6061653 YP_001729606.1 CDS ybdO NC_010473.1 688531 689433 R DNA-binding transcriptional regulator complement(688531..689433) Escherichia coli str. K-12 substr. DH10B 6061657 YP_001729607.1 CDS dsbG NC_010473.1 689642 690388 R Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase complement(689642..690388) Escherichia coli str. K-12 substr. DH10B 6061665 YP_001729608.1 CDS ahpC NC_010473.1 690760 691323 D with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase subunit C 690760..691323 Escherichia coli str. K-12 substr. DH10B 6059484 YP_001729609.1 CDS ahpF NC_010473.1 691568 693133 D alkyl hydroperoxide reductase, F52a subunit, FAD/NAD(P)-binding 691568..693133 Escherichia coli str. K-12 substr. DH10B 6061650 YP_001729610.1 CDS uspG NC_010473.1 693254 693682 R universal stress protein UP12 complement(693254..693682) Escherichia coli str. K-12 substr. DH10B 6061637 YP_001729611.1 CDS ybdR NC_010473.1 693903 695141 D oxidoreductase, Zn-dependent and NAD(P)-binding 693903..695141 Escherichia coli str. K-12 substr. DH10B 6061643 YP_001729612.1 CDS rnk NC_010473.1 695372 695782 R Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator complement(695372..695782) Escherichia coli str. K-12 substr. DH10B 6061634 YP_001729613.1 CDS rna NC_010473.1 696012 696818 R ribonuclease I complement(696012..696818) Escherichia coli str. K-12 substr. DH10B 6061626 YP_001729614.1 CDS citT NC_010473.1 696932 698395 R citrate:succinate antiporter complement(696932..698395) Escherichia coli str. K-12 substr. DH10B 6061628 YP_001729615.1 CDS citG NC_010473.1 698446 699324 R catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA; triphosphoribosyl-dephospho-CoA synthase complement(698446..699324) Escherichia coli str. K-12 substr. DH10B 6061624 YP_001729616.1 CDS citX NC_010473.1 699299 699850 R 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate; 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase complement(699299..699850) Escherichia coli str. K-12 substr. DH10B 6061633 YP_001729617.1 CDS citF NC_010473.1 699854 701386 R citrate lyase, citrate-ACP transferase (alpha) subunit complement(699854..701386) Escherichia coli str. K-12 substr. DH10B 6061619 YP_001729618.1 CDS citE NC_010473.1 701397 702305 R citrate lyase, citryl-ACP lyase (beta) subunit complement(701397..702305) Escherichia coli str. K-12 substr. DH10B 6061620 YP_001729619.1 CDS citD NC_010473.1 702302 702598 R acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma complement(702302..702598) Escherichia coli str. K-12 substr. DH10B 6061613 YP_001729620.1 CDS citC NC_010473.1 702613 703671 R citrate lyase synthetase complement(702613..703671) Escherichia coli str. K-12 substr. DH10B 6061622 YP_001729621.1 CDS citA NC_010473.1 704050 705708 D sensory histidine kinase in two-component regulatory system with citB 704050..705708 Escherichia coli str. K-12 substr. DH10B 6061649 YP_001729622.1 CDS dpiA NC_010473.1 705677 706357 D regulates the expression of citAB in citrate fermentation; two-component response regulator DpiA 705677..706357 Escherichia coli str. K-12 substr. DH10B 6061635 YP_001729623.1 CDS dcuC NC_010473.1 706398 707783 R responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC complement(706398..707783) Escherichia coli str. K-12 substr. DH10B 6061606 YP_001729624.1 CDS pagP NC_010473.1 708372 708932 D catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 708372..708932 Escherichia coli str. K-12 substr. DH10B 6061607 YP_001729625.1 CDS cspE NC_010473.1 709107 709316 D member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 709107..709316 Escherichia coli str. K-12 substr. DH10B 6061604 YP_001729626.1 CDS crcB NC_010473.1 709370 709753 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(709370..709753) Escherichia coli str. K-12 substr. DH10B 6061605 YP_001729627.1 CDS tatE NC_010473.1 710762 710965 D TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein E 710762..710965 Escherichia coli str. K-12 substr. DH10B 6061464 YP_001729628.1 CDS lipA NC_010473.1 711066 712031 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(711066..712031) Escherichia coli str. K-12 substr. DH10B 6061601 YP_001729629.1 CDS ybeF NC_010473.1 712240 713193 R putative DNA-binding transcriptional regulator complement(712240..713193) Escherichia coli str. K-12 substr. DH10B 6061593 YP_001729630.1 CDS lipB NC_010473.1 713452 714093 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(713452..714093) Escherichia coli str. K-12 substr. DH10B 6061594 YP_001729631.1 CDS ybeD NC_010473.1 714194 714457 R hypothetical protein complement(714194..714457) Escherichia coli str. K-12 substr. DH10B 6061584 YP_001729632.1 CDS dacA NC_010473.1 714567 715778 R penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase complement(714567..715778) Escherichia coli str. K-12 substr. DH10B 6061576 YP_001729633.1 CDS rlpA NC_010473.1 715917 717005 R rare lipoprotein A complement(715917..717005) Escherichia coli str. K-12 substr. DH10B 6061569 YP_001729634.1 CDS mrdB NC_010473.1 717016 718128 R cell wall shape-determining protein complement(717016..718128) Escherichia coli str. K-12 substr. DH10B 6061573 YP_001729635.1 CDS mrdA NC_010473.1 718131 720032 R penicillin-binding protein 2 complement(718131..720032) Escherichia coli str. K-12 substr. DH10B 6061562 YP_001729636.1 CDS ybeA NC_010473.1 720063 720530 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(720063..720530) Escherichia coli str. K-12 substr. DH10B 6061575 YP_001729637.1 CDS ybeB NC_010473.1 720534 720851 R hypothetical protein complement(720534..720851) Escherichia coli str. K-12 substr. DH10B 6061552 YP_001729638.1 CDS cobC NC_010473.1 721111 721722 R alpha-ribazole-5'-phosphate phosphatase complement(721111..721722) Escherichia coli str. K-12 substr. DH10B 6061556 YP_001729639.1 CDS nadD NC_010473.1 721746 722387 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase complement(721746..722387) Escherichia coli str. K-12 substr. DH10B 6061549 YP_001729640.1 CDS holA NC_010473.1 722389 723420 R required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta complement(722389..723420) Escherichia coli str. K-12 substr. DH10B 6061561 YP_001729641.1 CDS rlpB NC_010473.1 723420 724001 R rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB complement(723420..724001) Escherichia coli str. K-12 substr. DH10B 6061598 YP_001729642.1 CDS leuS NC_010473.1 724016 726598 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(724016..726598) Escherichia coli str. K-12 substr. DH10B 6061586 YP_001729643.1 CDS ybeL NC_010473.1 726833 727315 D hypothetical protein 726833..727315 Escherichia coli str. K-12 substr. DH10B 6059098 YP_001729644.1 CDS ybeQ NC_010473.1 727385 728362 R hypothetical protein complement(727385..728362) Escherichia coli str. K-12 substr. DH10B 6061542 YP_001729645.1 CDS ybeR NC_010473.1 728526 729233 D hypothetical protein 728526..729233 Escherichia coli str. K-12 substr. DH10B 6061544 YP_001729646.1 CDS djlB NC_010473.1 729230 730657 D chaperone 729230..730657 Escherichia coli str. K-12 substr. DH10B 6061529 YP_001729647.1 CDS ybeT NC_010473.1 730667 731221 R outer membrane protein complement(730667..731221) Escherichia coli str. K-12 substr. DH10B 6061535 YP_001729648.1 CDS ybeU NC_010473.1 731323 732030 D tRNA ligase 731323..732030 Escherichia coli str. K-12 substr. DH10B 6061548 YP_001729649.1 CDS djlC NC_010473.1 732027 733478 D Hsc56 co-chaperone of HscC 732027..733478 Escherichia coli str. K-12 substr. DH10B 6061525 YP_001729650.1 CDS hscC NC_010473.1 733538 735208 R Hsp70 family chaperone Hsc62, binds to RpoD and inhibits transcription complement(733538..735208) Escherichia coli str. K-12 substr. DH10B 6061520 YP_001729651.1 CDS rihA NC_010473.1 735292 736227 R Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 complement(735292..736227) Escherichia coli str. K-12 substr. DH10B 6061522 YP_001729652.1 CDS gltL NC_010473.1 736345 737070 R glutamate/aspartate ABC transporter ATP-binding protein complement(736345..737070) Escherichia coli str. K-12 substr. DH10B 6061517 YP_001729653.1 CDS gltK NC_010473.1 737070 737744 R glutamate/aspartate ABC transporter membrane protein complement(737070..737744) Escherichia coli str. K-12 substr. DH10B 6061509 YP_001729654.1 CDS gltJ NC_010473.1 737744 738484 R glutamate/aspartate ABC transporter membrane protein complement(737744..738484) Escherichia coli str. K-12 substr. DH10B 6061512 YP_001729655.1 CDS gltI NC_010473.1 738654 739562 R glutamate and aspartate transporter subunit complement(738654..739562) Escherichia coli str. K-12 substr. DH10B 6061500 YP_001729656.1 CDS ECDH10B_0725 NC_010473.1 739812 740828 R IS5 transposase and trans-activator complement(739812..740828) Escherichia coli str. K-12 substr. DH10B 6061514 YP_001729657.1 CDS lnt NC_010473.1 741158 742696 R Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase complement(741158..742696) Escherichia coli str. K-12 substr. DH10B 6061493 YP_001729658.1 CDS corC NC_010473.1 742721 743599 R ion transport complement(742721..743599) Escherichia coli str. K-12 substr. DH10B 6061497 YP_001729659.1 CDS ybeY NC_010473.1 743689 744156 R putative metalloprotease complement(743689..744156) Escherichia coli str. K-12 substr. DH10B 6061491 YP_001729660.1 CDS ybeZ NC_010473.1 744153 745193 R nucleoside triphosphate hydrolase domain-containing protein complement(744153..745193) Escherichia coli str. K-12 substr. DH10B 6061499 YP_001729661.1 CDS miaB NC_010473.1 745346 746770 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(745346..746770) Escherichia coli str. K-12 substr. DH10B 6061524 YP_001729662.1 CDS ubiF NC_010473.1 746916 748091 D catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 746916..748091 Escherichia coli str. K-12 substr. DH10B 6061519 YP_001729663.1 CDS asnB NC_010473.1 749328 750992 R functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B complement(749328..750992) Escherichia coli str. K-12 substr. DH10B 6061769 YP_001729664.1 CDS nagD NC_010473.1 751389 752141 R UMP phosphatase complement(751389..752141) Escherichia coli str. K-12 substr. DH10B 6061479 YP_001729665.1 CDS nagC NC_010473.1 752189 753409 R DNA-binding transcriptional dual regulator complement(752189..753409) Escherichia coli str. K-12 substr. DH10B 6061472 YP_001729666.1 CDS nagA NC_010473.1 753418 754566 R catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase complement(753418..754566) Escherichia coli str. K-12 substr. DH10B 6061473 YP_001729667.1 CDS nagB NC_010473.1 754626 755426 R catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase complement(754626..755426) Escherichia coli str. K-12 substr. DH10B 6061489 YP_001729668.1 CDS nagE NC_010473.1 755759 757705 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunit IIABC 755759..757705 Escherichia coli str. K-12 substr. DH10B 6061470 YP_001729669.1 CDS glnS NC_010473.1 757908 759572 D catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 757908..759572 Escherichia coli str. K-12 substr. DH10B 6061458 YP_001729670.1 CDS ybfM NC_010473.1 760149 761555 D outer membrane porin 760149..761555 Escherichia coli str. K-12 substr. DH10B 6061466 YP_001729671.1 CDS ybfN NC_010473.1 761605 761931 D lipoprotein 761605..761931 Escherichia coli str. K-12 substr. DH10B 6061453 YP_001729672.1 CDS fur NC_010473.1 762015 762461 R negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator complement(762015..762461) Escherichia coli str. K-12 substr. DH10B 6061442 YP_001729673.1 CDS fldA NC_010473.1 762750 763280 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA complement(762750..763280) Escherichia coli str. K-12 substr. DH10B 6061448 YP_001729674.1 CDS ybfE NC_010473.1 763420 763713 R LexA regulated protein complement(763420..763713) Escherichia coli str. K-12 substr. DH10B 6061438 YP_001729675.1 CDS ybfF NC_010473.1 763853 764617 R hypothetical protein complement(763853..764617) Escherichia coli str. K-12 substr. DH10B 6061451 YP_001729676.1 CDS seqA NC_010473.1 764802 765347 D negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 764802..765347 Escherichia coli str. K-12 substr. DH10B 6061434 YP_001729677.1 CDS pgm NC_010473.1 765373 767013 D catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 765373..767013 Escherichia coli str. K-12 substr. DH10B 6061435 YP_001729678.1 CDS ybfP NC_010473.1 767227 767721 D hypothetical protein 767227..767721 Escherichia coli str. K-12 substr. DH10B 6061429 YP_001729679.1 CDS potE NC_010473.1 768761 770080 R catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter complement(768761..770080) Escherichia coli str. K-12 substr. DH10B 6061283 YP_001729680.1 CDS speF NC_010473.1 770077 772275 R ornithine decarboxylase complement(770077..772275) Escherichia coli str. K-12 substr. DH10B 6061469 YP_001729681.1 CDS kdpE NC_010473.1 772871 773548 R response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE complement(772871..773548) Escherichia coli str. K-12 substr. DH10B 6061456 YP_001729682.1 CDS kdpD NC_010473.1 773545 776229 R sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD complement(773545..776229) Escherichia coli str. K-12 substr. DH10B 6061424 YP_001729683.1 CDS kdpC NC_010473.1 776222 776794 R One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C complement(776222..776794) Escherichia coli str. K-12 substr. DH10B 6061426 YP_001729684.1 CDS kdpB NC_010473.1 776803 778851 R One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B complement(776803..778851) Escherichia coli str. K-12 substr. DH10B 6061422 YP_001729685.1 CDS kdpA NC_010473.1 778874 780547 R catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A complement(778874..780547) Escherichia coli str. K-12 substr. DH10B 6061423 YP_001729686.1 CDS kdpF NC_010473.1 780547 780636 R one of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit F complement(780547..780636) Escherichia coli str. K-12 substr. DH10B 6061427 YP_001729687.1 CDS ybfA NC_010473.1 780949 781155 D hypothetical protein 780949..781155 Escherichia coli str. K-12 substr. DH10B 6061420 YP_001729688.1 CDS rhsC NC_010473.1 781398 785591 D rhsC element core protein RhsC 781398..785591 Escherichia coli str. K-12 substr. DH10B 6061414 YP_001729689.1 CDS ybfB NC_010473.1 785591 785917 D inner membrane protein 785591..785917 Escherichia coli str. K-12 substr. DH10B 6061417 YP_001729690.1 CDS ybfO NC_010473.1 786035 787468 D protein, rhs-like protein 786035..787468 Escherichia coli str. K-12 substr. DH10B 6061407 YP_001729691.1 CDS ybfC NC_010473.1 787465 788034 D hypothetical protein 787465..788034 Escherichia coli str. K-12 substr. DH10B 6061391 YP_001729692.1 CDS ybfQ NC_010473.1 788260 788514 D transposase 788260..788514 Escherichia coli str. K-12 substr. DH10B 6061396 YP_001729693.1 CDS ybfD NC_010473.1 789907 790668 D hypothetical protein 789907..790668 Escherichia coli str. K-12 substr. DH10B 6058485 YP_001729694.1 CDS ybgA NC_010473.1 790816 791325 D hypothetical protein 790816..791325 Escherichia coli str. K-12 substr. DH10B 6061404 YP_001729695.1 CDS phr NC_010473.1 791322 792740 D UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 791322..792740 Escherichia coli str. K-12 substr. DH10B 6061381 YP_001729696.1 CDS ybgH NC_010473.1 792890 794371 R transporter complement(792890..794371) Escherichia coli str. K-12 substr. DH10B 6061382 YP_001729697.1 CDS ybgI NC_010473.1 794642 795385 D putative hydrolase-oxidase 794642..795385 Escherichia coli str. K-12 substr. DH10B 6061379 YP_001729698.1 CDS ybgJ NC_010473.1 795408 796064 D allophanate hydrolase subunit 1 795408..796064 Escherichia coli str. K-12 substr. DH10B 6061388 YP_001729699.1 CDS ybgK NC_010473.1 796058 796990 D allophanate hydrolase subunit 2 796058..796990 Escherichia coli str. K-12 substr. DH10B 6061418 YP_001729700.1 CDS ybgL NC_010473.1 796980 797714 D LamB/YcsF family protein 796980..797714 Escherichia coli str. K-12 substr. DH10B 6061411 YP_001729701.1 CDS nei NC_010473.1 797750 798541 D 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity; endonuclease VIII 797750..798541 Escherichia coli str. K-12 substr. DH10B 6061373 YP_001729702.1 CDS abrB NC_010473.1 798538 799584 R regulator complement(798538..799584) Escherichia coli str. K-12 substr. DH10B 6061376 YP_001729703.1 CDS ybgO NC_010473.1 799736 800797 R fimbrial-like adhesin protein complement(799736..800797) Escherichia coli str. K-12 substr. DH10B 6061365 YP_001729704.1 CDS ybgP NC_010473.1 800794 801522 R assembly protein complement(800794..801522) Escherichia coli str. K-12 substr. DH10B 6061368 YP_001729705.1 CDS ybgQ NC_010473.1 801537 803984 R outer membrane protein complement(801537..803984) Escherichia coli str. K-12 substr. DH10B 6061378 YP_001729706.1 CDS ybgD NC_010473.1 804044 804610 R fimbrial-like adhesin protein complement(804044..804610) Escherichia coli str. K-12 substr. DH10B 6061362 YP_001729707.1 CDS gltA NC_010473.1 805000 806283 R type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase complement(805000..806283) Escherichia coli str. K-12 substr. DH10B 6061339 YP_001729708.1 CDS sdhC NC_010473.1 806992 807381 D succinate dehydrogenase cytochrome b556 large membrane subunit 806992..807381 Escherichia coli str. K-12 substr. DH10B 6061355 YP_001729709.1 CDS sdhD NC_010473.1 807375 807722 D succinate dehydrogenase cytochrome b556 small membrane subunit 807375..807722 Escherichia coli str. K-12 substr. DH10B 6061335 YP_001729710.1 CDS sdhA NC_010473.1 807722 809488 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 807722..809488 Escherichia coli str. K-12 substr. DH10B 6061321 YP_001729711.1 CDS sdhB NC_010473.1 809504 810220 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 809504..810220 Escherichia coli str. K-12 substr. DH10B 6061325 YP_001729712.1 CDS sucA NC_010473.1 810521 813322 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 810521..813322 Escherichia coli str. K-12 substr. DH10B 6061319 YP_001729713.1 CDS sucB NC_010473.1 813337 814554 D component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 813337..814554 Escherichia coli str. K-12 substr. DH10B 6061328 YP_001729714.1 CDS sucC NC_010473.1 814829 815995 D catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 814829..815995 Escherichia coli str. K-12 substr. DH10B 6061306 YP_001729715.1 CDS sucD NC_010473.1 815995 816864 D Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 815995..816864 Escherichia coli str. K-12 substr. DH10B 6061313 YP_001729716.1 CDS mngR NC_010473.1 816968 817690 R regulates the succiny-lCoA synthetase operon; DNA-binding transcriptional repressor MngR complement(816968..817690) Escherichia coli str. K-12 substr. DH10B 6061302 YP_001729717.1 CDS mngA NC_010473.1 817799 819775 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC 817799..819775 Escherichia coli str. K-12 substr. DH10B 6061317 YP_001729718.1 CDS mngB NC_010473.1 819793 822426 D alpha-mannosidase 819793..822426 Escherichia coli str. K-12 substr. DH10B 6061356 YP_001729719.1 CDS cydA NC_010473.1 823273 824841 D cytochrome d terminal oxidase, subunit I 823273..824841 Escherichia coli str. K-12 substr. DH10B 6061337 YP_001729720.1 CDS cydB NC_010473.1 824857 825996 D cytochrome d terminal oxidase, subunit II 824857..825996 Escherichia coli str. K-12 substr. DH10B 6061288 YP_001729721.1 CDS ybgT NC_010473.1 826011 826124 D hypothetical protein 826011..826124 Escherichia coli str. K-12 substr. DH10B 6061291 YP_001729722.1 CDS ybgE NC_010473.1 826124 826417 D hypothetical protein 826124..826417 Escherichia coli str. K-12 substr. DH10B 6061280 YP_001729723.1 CDS ybgC NC_010473.1 826567 826971 D catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase YbgC 826567..826971 Escherichia coli str. K-12 substr. DH10B 6061286 YP_001729724.1 CDS tolQ NC_010473.1 826968 827660 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 826968..827660 Escherichia coli str. K-12 substr. DH10B 6061293 YP_001729725.1 CDS tolR NC_010473.1 827664 828092 D membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 827664..828092 Escherichia coli str. K-12 substr. DH10B 6061274 YP_001729726.1 CDS tolA NC_010473.1 828157 829422 D inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 828157..829422 Escherichia coli str. K-12 substr. DH10B 6061260 YP_001729727.1 CDS tolB NC_010473.1 829555 830847 D forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 829555..830847 Escherichia coli str. K-12 substr. DH10B 6061267 YP_001729728.1 CDS pal NC_010473.1 830882 831403 D peptidoglycan-associated outer membrane lipoprotein 830882..831403 Escherichia coli str. K-12 substr. DH10B 6061254 YP_001729729.1 CDS ybgF NC_010473.1 831413 832204 D periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 831413..832204 Escherichia coli str. K-12 substr. DH10B 6061237 YP_001729730.1 CDS nadA NC_010473.1 833900 834943 D 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 833900..834943 Escherichia coli str. K-12 substr. DH10B 6062128 YP_001729731.1 CDS pnuC NC_010473.1 834981 835700 D nicotinamide mononucleotide transporter 834981..835700 Escherichia coli str. K-12 substr. DH10B 6061235 YP_001729732.1 CDS zitB NC_010473.1 835697 836638 R involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB complement(835697..836638) Escherichia coli str. K-12 substr. DH10B 6061248 YP_001729733.1 CDS ybgS NC_010473.1 836752 837132 R hypothetical protein complement(836752..837132) Escherichia coli str. K-12 substr. DH10B 6061213 YP_001729734.1 CDS aroG NC_010473.1 837448 838500 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 837448..838500 Escherichia coli str. K-12 substr. DH10B 6061215 YP_001729735.1 CDS gpmA NC_010473.1 838658 839410 R 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase complement(838658..839410) Escherichia coli str. K-12 substr. DH10B 6061197 YP_001729736.1 CDS galM NC_010473.1 839612 840652 R catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase complement(839612..840652) Escherichia coli str. K-12 substr. DH10B 6061225 YP_001729737.1 CDS galT NC_010473.1 843134 844180 R catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase complement(843134..844180) Escherichia coli str. K-12 substr. DH10B 6061289 YP_001729738.1 CDS galE NC_010473.1 844190 845206 R UDP-galactose-4-epimerase complement(844190..845206) Escherichia coli str. K-12 substr. DH10B 6061257 YP_001729739.1 CDS modF NC_010473.1 845467 846939 R contains 2 ATP-binding cassettes; involved in the transport of molybdenum; putative molybdenum transport ATP-binding protein ModF complement(845467..846939) Escherichia coli str. K-12 substr. DH10B 6061180 YP_001729740.1 CDS modE NC_010473.1 847007 847795 R represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE complement(847007..847795) Escherichia coli str. K-12 substr. DH10B 6061183 YP_001729741.1 CDS ybhT NC_010473.1 847924 848073 D hypothetical protein 847924..848073 Escherichia coli str. K-12 substr. DH10B 6061176 YP_001729742.1 CDS modA NC_010473.1 848240 849013 D with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 848240..849013 Escherichia coli str. K-12 substr. DH10B 6061177 YP_001729743.1 CDS modB NC_010473.1 849013 849702 D part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 849013..849702 Escherichia coli str. K-12 substr. DH10B 6061193 YP_001729744.1 CDS modC NC_010473.1 849705 850763 D Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 849705..850763 Escherichia coli str. K-12 substr. DH10B 6061174 YP_001729745.1 CDS ybhA NC_010473.1 850764 851582 R YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase complement(850764..851582) Escherichia coli str. K-12 substr. DH10B 6061165 YP_001729746.1 CDS pgl NC_010473.1 851737 852732 D catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 851737..852732 Escherichia coli str. K-12 substr. DH10B 6061170 YP_001729747.1 CDS ybhD NC_010473.1 852773 853726 R DNA-binding transcriptional regulator complement(852773..853726) Escherichia coli str. K-12 substr. DH10B 6061159 YP_001729748.1 CDS ybhH NC_010473.1 853910 854962 D hypothetical protein 853910..854962 Escherichia coli str. K-12 substr. DH10B 6061143 YP_001729749.1 CDS ybhI NC_010473.1 855038 856471 D transporter 855038..856471 Escherichia coli str. K-12 substr. DH10B 6061145 YP_001729750.1 CDS ybhJ NC_010473.1 856654 858915 D hypothetical protein 856654..858915 Escherichia coli str. K-12 substr. DH10B 6061137 YP_001729751.1 CDS ybhC NC_010473.1 859149 860432 R outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family; putative pectinesterase complement(859149..860432) Escherichia coli str. K-12 substr. DH10B 6061157 YP_001729752.1 CDS ybhB NC_010473.1 860584 861060 R YbhB; similar to rat and human kinase inhibitory proteins; putative kinase inhibitor protein complement(860584..861060) Escherichia coli str. K-12 substr. DH10B 6061127 YP_001729753.1 CDS bioA NC_010473.1 861119 862408 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase complement(861119..862408) Escherichia coli str. K-12 substr. DH10B 6061129 YP_001729754.1 CDS bioB NC_010473.1 862495 863535 D biotin synthase 862495..863535 Escherichia coli str. K-12 substr. DH10B 6061126 YP_001729755.1 CDS bioF NC_010473.1 863532 864686 D catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 863532..864686 Escherichia coli str. K-12 substr. DH10B 6061136 YP_001729756.1 CDS bioC NC_010473.1 864673 865428 D putative methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC 864673..865428 Escherichia coli str. K-12 substr. DH10B 6061173 YP_001729757.1 CDS bioD NC_010473.1 865421 866098 D DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 865421..866098 Escherichia coli str. K-12 substr. DH10B 6061163 YP_001729758.1 CDS uvrB NC_010473.1 866677 868698 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 866677..868698 Escherichia coli str. K-12 substr. DH10B 6061119 YP_001729759.1 CDS ybhK NC_010473.1 868890 869798 R transferase complement(868890..869798) Escherichia coli str. K-12 substr. DH10B 6061122 YP_001729760.1 CDS moaA NC_010473.1 870195 871184 D together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 870195..871184 Escherichia coli str. K-12 substr. DH10B 6061096 YP_001729761.1 CDS moaB NC_010473.1 871206 871718 D molybdopterin biosynthesis protein B 871206..871718 Escherichia coli str. K-12 substr. DH10B 6061097 YP_001729762.1 CDS moaC NC_010473.1 871721 872206 D MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 871721..872206 Escherichia coli str. K-12 substr. DH10B 6061125 YP_001729763.1 CDS moaD NC_010473.1 872199 872444 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 872199..872444 Escherichia coli str. K-12 substr. DH10B 6061094 YP_001729764.1 CDS moaE NC_010473.1 872446 872898 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 872446..872898 Escherichia coli str. K-12 substr. DH10B 6061087 YP_001729765.1 CDS ybhL NC_010473.1 873035 873739 D inner membrane protein 873035..873739 Escherichia coli str. K-12 substr. DH10B 6061089 YP_001729766.1 CDS ybhM NC_010473.1 873944 874657 D inner membrane protein 873944..874657 Escherichia coli str. K-12 substr. DH10B 6061079 YP_001729767.1 CDS ybhN NC_010473.1 874693 875649 R inner membrane protein complement(874693..875649) Escherichia coli str. K-12 substr. DH10B 6061068 YP_001729768.1 CDS ybhO NC_010473.1 875649 876890 R cardiolipin synthase 2 complement(875649..876890) Escherichia coli str. K-12 substr. DH10B 6061070 YP_001729769.1 CDS ybhP NC_010473.1 876887 877648 R DNase complement(876887..877648) Escherichia coli str. K-12 substr. DH10B 6061064 YP_001729770.1 CDS ybhQ NC_010473.1 877781 878191 D inner membrane protein 877781..878191 Escherichia coli str. K-12 substr. DH10B 6061077 YP_001729771.1 CDS ybhR NC_010473.1 878153 879259 R ABC transporter membrane protein complement(878153..879259) Escherichia coli str. K-12 substr. DH10B 6061047 YP_001729772.1 CDS ybhS NC_010473.1 879270 880403 R ABC transporter membrane protein complement(879270..880403) Escherichia coli str. K-12 substr. DH10B 6061052 YP_001729773.1 CDS ybhF NC_010473.1 880396 882132 R ABC transporter ATP-binding protein complement(880396..882132) Escherichia coli str. K-12 substr. DH10B 6061046 YP_001729774.1 CDS ybhG NC_010473.1 882125 883123 R hypothetical protein complement(882125..883123) Escherichia coli str. K-12 substr. DH10B 6061054 YP_001729775.1 CDS ybiH NC_010473.1 883123 883794 R putative DNA-binding transcriptional regulator complement(883123..883794) Escherichia coli str. K-12 substr. DH10B 6061091 YP_001729776.1 CDS rhlE NC_010473.1 884023 885387 D this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 884023..885387 Escherichia coli str. K-12 substr. DH10B 6061080 YP_001729777.1 CDS ybiA NC_010473.1 885619 886101 R hypothetical protein complement(885619..886101) Escherichia coli str. K-12 substr. DH10B 6061036 YP_001729778.1 CDS dinG NC_010473.1 886221 888371 D helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 886221..888371 Escherichia coli str. K-12 substr. DH10B 6061038 YP_001729779.1 CDS ybiB NC_010473.1 888399 889361 D glycosyl transferase family protein 888399..889361 Escherichia coli str. K-12 substr. DH10B 6061032 YP_001729780.1 CDS ybiC NC_010473.1 889502 890587 D hypothetical protein 889502..890587 Escherichia coli str. K-12 substr. DH10B 6061035 YP_001729781.1 CDS ybiJ NC_010473.1 890816 891076 R hypothetical protein complement(890816..891076) Escherichia coli str. K-12 substr. DH10B 6061042 YP_001729782.1 CDS ybiI NC_010473.1 891341 891607 R hypothetical protein complement(891341..891607) Escherichia coli str. K-12 substr. DH10B 6061030 YP_001729783.1 CDS ybiX NC_010473.1 891681 892358 R putative hydroxylase complement(891681..892358) Escherichia coli str. K-12 substr. DH10B 6061026 YP_001729784.1 CDS fiu NC_010473.1 892400 894682 R Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu complement(892400..894682) Escherichia coli str. K-12 substr. DH10B 6061028 YP_001729785.1 CDS ybiM NC_010473.1 894947 895207 R hypothetical protein complement(894947..895207) Escherichia coli str. K-12 substr. DH10B 6061008 YP_001729786.1 CDS ybiN NC_010473.1 895483 896409 D putative SAM-dependent methyltransferase 895483..896409 Escherichia coli str. K-12 substr. DH10B 6061000 YP_001729787.1 CDS ybiO NC_010473.1 896406 898631 R hypothetical protein complement(896406..898631) Escherichia coli str. K-12 substr. DH10B 6061001 YP_001729788.1 CDS glnQ NC_010473.1 898892 899614 R similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein complement(898892..899614) Escherichia coli str. K-12 substr. DH10B 6060989 YP_001729789.1 CDS glnP NC_010473.1 899611 900270 R similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease complement(899611..900270) Escherichia coli str. K-12 substr. DH10B 6061003 YP_001729790.1 CDS glnH NC_010473.1 900409 901155 R similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein complement(900409..901155) Escherichia coli str. K-12 substr. DH10B 6060972 YP_001729791.1 CDS dps NC_010473.1 901559 902062 R binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps complement(901559..902062) Escherichia coli str. K-12 substr. DH10B 6060977 YP_001729792.1 CDS rhtA NC_010473.1 902361 903248 R threonine and homoserine efflux system complement(902361..903248) Escherichia coli str. K-12 substr. DH10B 6060969 YP_001729793.1 CDS ompX NC_010473.1 903601 904116 D OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 903601..904116 Escherichia coli str. K-12 substr. DH10B 6060986 YP_001729794.1 CDS ybiP NC_010473.1 904165 905748 R hydrolase, inner membrane complement(904165..905748) Escherichia coli str. K-12 substr. DH10B 6061029 YP_001729795.1 CDS yliL NC_010473.1 905822 906091 D hypothetical protein 905822..906091 Escherichia coli str. K-12 substr. DH10B 6061023 YP_001729796.1 CDS mntR NC_010473.1 906334 906801 D Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 906334..906801 Escherichia coli str. K-12 substr. DH10B 6062164 YP_001729797.1 CDS ybiR NC_010473.1 906798 907916 D transporter 906798..907916 Escherichia coli str. K-12 substr. DH10B 6060959 YP_001729798.1 CDS ybiS NC_010473.1 907975 908895 R hypothetical protein complement(907975..908895) Escherichia coli str. K-12 substr. DH10B 6060945 YP_001729799.1 CDS ybiT NC_010473.1 909114 910706 D ABC transporter ATP-binding protein 909114..910706 Escherichia coli str. K-12 substr. DH10B 6060949 YP_001729800.1 CDS ybiU NC_010473.1 910947 912212 R hypothetical protein complement(910947..912212) Escherichia coli str. K-12 substr. DH10B 6060960 YP_001729801.1 CDS ybiV NC_010473.1 912364 913179 R hydrolase complement(912364..913179) Escherichia coli str. K-12 substr. DH10B 6060942 YP_001729802.1 CDS ybiW NC_010473.1 913325 915757 R pyruvate formate lyase complement(913325..915757) Escherichia coli str. K-12 substr. DH10B 6060936 YP_001729803.1 CDS ybiY NC_010473.1 915763 916689 R pyruvate formate lyase activating enzyme complement(915763..916689) Escherichia coli str. K-12 substr. DH10B 6060937 YP_001729804.1 CDS fsaA NC_010473.1 916793 917455 D similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 916793..917455 Escherichia coli str. K-12 substr. DH10B 6060929 YP_001729805.1 CDS moeB NC_010473.1 917531 918280 R ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB complement(917531..918280) Escherichia coli str. K-12 substr. DH10B 6060922 YP_001729806.1 CDS moeA NC_010473.1 918280 919515 R is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA complement(918280..919515) Escherichia coli str. K-12 substr. DH10B 6060923 YP_001729807.1 CDS iaaA NC_010473.1 919719 920684 D L-asparaginase 919719..920684 Escherichia coli str. K-12 substr. DH10B 6060921 YP_001729808.1 CDS gsiA NC_010473.1 920671 922542 D with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 920671..922542 Escherichia coli str. K-12 substr. DH10B 6060924 YP_001729809.1 CDS gsiB NC_010473.1 922562 924100 D periplasmic solute-binding component of a glutathione transporter 922562..924100 Escherichia coli str. K-12 substr. DH10B 6060911 YP_001729810.1 CDS gsiC NC_010473.1 924118 925038 D permease component of a glutathione transporter 924118..925038 Escherichia coli str. K-12 substr. DH10B 6060913 YP_001729811.1 CDS gsiD NC_010473.1 925041 925952 D permease component of a glutathione transporter 925041..925952 Escherichia coli str. K-12 substr. DH10B 6060909 YP_001729812.1 CDS yliE NC_010473.1 926130 928478 D inner membrane protein 926130..928478 Escherichia coli str. K-12 substr. DH10B 6060915 YP_001729813.1 CDS yliF NC_010473.1 928486 929814 D diguanylate cyclase 928486..929814 Escherichia coli str. K-12 substr. DH10B 6060939 YP_001729814.1 CDS rimO NC_010473.1 929861 931186 R catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase complement(929861..931186) Escherichia coli str. K-12 substr. DH10B 6060931 YP_001729815.1 CDS bssR NC_010473.1 931399 931782 D BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 931399..931782 Escherichia coli str. K-12 substr. DH10B 6060885 YP_001729816.1 CDS yliI NC_010473.1 931893 933008 D dehydrogenase 931893..933008 Escherichia coli str. K-12 substr. DH10B 6060888 YP_001729817.1 CDS yliJ NC_010473.1 933005 933631 R glutathione S-transferase complement(933005..933631) Escherichia coli str. K-12 substr. DH10B 6060876 YP_001729818.1 CDS dacC NC_010473.1 933878 935080 D penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 933878..935080 Escherichia coli str. K-12 substr. DH10B 6060877 YP_001729819.1 CDS deoR NC_010473.1 935127 935885 R DNA-binding transcriptional repressor DeoR complement(935127..935885) Escherichia coli str. K-12 substr. DH10B 6060906 YP_001729820.1 CDS ybjG NC_010473.1 935943 936539 R undecaprenyl pyrophosphate phosphatase complement(935943..936539) Escherichia coli str. K-12 substr. DH10B 6060873 YP_001729821.1 CDS cmr NC_010473.1 936824 938056 D multidrug efflux system protein 936824..938056 Escherichia coli str. K-12 substr. DH10B 6060869 YP_001729822.1 CDS ybjH NC_010473.1 938097 938381 R hypothetical protein complement(938097..938381) Escherichia coli str. K-12 substr. DH10B 6060871 YP_001729823.1 CDS ybjI NC_010473.1 938467 939282 R hypothetical protein complement(938467..939282) Escherichia coli str. K-12 substr. DH10B 6060860 YP_001729824.1 CDS ybjJ NC_010473.1 939282 940490 R transporter complement(939282..940490) Escherichia coli str. K-12 substr. DH10B 6060845 YP_001729825.1 CDS ybjK NC_010473.1 940574 941110 D DNA-binding transcriptional regulator 940574..941110 Escherichia coli str. K-12 substr. DH10B 6060850 YP_001729826.1 CDS ybjL NC_010473.1 941285 942970 R hypothetical protein complement(941285..942970) Escherichia coli str. K-12 substr. DH10B 6058171 YP_001729827.1 CDS ybjM NC_010473.1 943240 943617 D inner membrane protein 943240..943617 Escherichia coli str. K-12 substr. DH10B 6060854 YP_001729828.1 CDS grxA NC_010473.1 943647 943904 R functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin complement(943647..943904) Escherichia coli str. K-12 substr. DH10B 6060838 YP_001729829.1 CDS ybjC NC_010473.1 944064 944351 D YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 944064..944351 Escherichia coli str. K-12 substr. DH10B 6060841 YP_001729830.1 CDS nfsA NC_010473.1 944335 945057 D NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 944335..945057 Escherichia coli str. K-12 substr. DH10B 6060833 YP_001729831.1 CDS rimK NC_010473.1 945118 946020 D responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 945118..946020 Escherichia coli str. K-12 substr. DH10B 6060843 YP_001729832.1 CDS ybjN NC_010473.1 946108 946584 D oxidoreductase 946108..946584 Escherichia coli str. K-12 substr. DH10B 6060872 YP_001729833.1 CDS potF NC_010473.1 946935 948047 D putrescine ABC transporter periplasmic-binding protein 946935..948047 Escherichia coli str. K-12 substr. DH10B 6060864 YP_001729834.1 CDS potG NC_010473.1 948142 949275 D part of the PotFGHI ATP-dependent putrescine transporter; putrescine ABC transporter ATP-binding protein 948142..949275 Escherichia coli str. K-12 substr. DH10B 6060826 YP_001729835.1 CDS potH NC_010473.1 949285 950238 D putrescine ABC transporter membrane protein 949285..950238 Escherichia coli str. K-12 substr. DH10B 6060827 YP_001729836.1 CDS potI NC_010473.1 950235 951080 D putrescine ABC transporter membrane protein 950235..951080 Escherichia coli str. K-12 substr. DH10B 6060821 YP_001729837.1 CDS ybjO NC_010473.1 951140 951628 D inner membrane protein 951140..951628 Escherichia coli str. K-12 substr. DH10B 6060822 YP_001729838.1 CDS rumB NC_010473.1 951669 952796 D RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 951669..952796 Escherichia coli str. K-12 substr. DH10B 6060828 YP_001729839.1 CDS artJ NC_010473.1 952995 953726 R arginine ABC transporter periplasmic-binding protein complement(952995..953726) Escherichia coli str. K-12 substr. DH10B 6060820 YP_001729840.1 CDS artM NC_010473.1 954017 954685 R with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM complement(954017..954685) Escherichia coli str. K-12 substr. DH10B 6060813 YP_001729841.1 CDS artQ NC_010473.1 954685 955401 R with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ complement(954685..955401) Escherichia coli str. K-12 substr. DH10B 6060818 YP_001729842.1 CDS artI NC_010473.1 955408 956139 R arginine ABC transporter periplasmic-binding protein complement(955408..956139) Escherichia coli str. K-12 substr. DH10B 6060809 YP_001729843.1 CDS artP NC_010473.1 956157 956885 R With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit complement(956157..956885) Escherichia coli str. K-12 substr. DH10B 6060802 YP_001729844.1 CDS ybjP NC_010473.1 957103 957618 R induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; putative lipoprotein complement(957103..957618) Escherichia coli str. K-12 substr. DH10B 6060804 YP_001729845.1 CDS ybjQ NC_010473.1 957744 958067 D hypothetical protein 957744..958067 Escherichia coli str. K-12 substr. DH10B 6060801 YP_001729846.1 CDS ybjR NC_010473.1 958064 958894 D amidase 958064..958894 Escherichia coli str. K-12 substr. DH10B 6060805 YP_001729847.1 CDS ybjS NC_010473.1 958891 959904 R NAD(P)-binding oxidoreductase complement(958891..959904) Escherichia coli str. K-12 substr. DH10B 6060797 YP_001729848.1 CDS ybjT NC_010473.1 960003 961433 R hypothetical protein complement(960003..961433) Escherichia coli str. K-12 substr. DH10B 6060799 YP_001729849.1 CDS ltaE NC_010473.1 961444 962445 R low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase complement(961444..962445) Escherichia coli str. K-12 substr. DH10B 6060796 YP_001729850.1 CDS poxB NC_010473.1 962482 964200 R catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase complement(962482..964200) Escherichia coli str. K-12 substr. DH10B 6060800 YP_001729851.1 CDS hcr NC_010473.1 964333 965301 R HCP oxidoreductase complement(964333..965301) Escherichia coli str. K-12 substr. DH10B 6060819 YP_001729852.1 CDS hcp NC_010473.1 965313 966965 R catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase complement(965313..966965) Escherichia coli str. K-12 substr. DH10B 6060812 YP_001729853.1 CDS ybjE NC_010473.1 967109 968008 R transporter complement(967109..968008) Escherichia coli str. K-12 substr. DH10B 6060785 YP_001729854.1 CDS aqpZ NC_010473.1 968503 969198 R porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z complement(968503..969198) Escherichia coli str. K-12 substr. DH10B 6060786 YP_001729855.1 CDS ybjD NC_010473.1 969624 971282 D contains the nonsynonymous change M498I; hypothetical protein 969624..971282 Escherichia coli str. K-12 substr. DH10B 6060777 YP_001729856.1 CDS ybjX NC_010473.1 971279 972271 R hypothetical protein complement(971279..972271) Escherichia coli str. K-12 substr. DH10B 6060781 YP_001729857.1 CDS macA NC_010473.1 972386 973501 D confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 972386..973501 Escherichia coli str. K-12 substr. DH10B 6060793 YP_001729858.1 CDS macB NC_010473.1 973498 975444 D with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease 973498..975444 Escherichia coli str. K-12 substr. DH10B 6060774 YP_001729859.1 CDS cspD NC_010473.1 975517 975741 R inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible; stationary phase/starvation inducible regulatory protein CspD complement(975517..975741) Escherichia coli str. K-12 substr. DH10B 6060768 YP_001729860.1 CDS clpS NC_010473.1 976064 976384 D involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 976064..976384 Escherichia coli str. K-12 substr. DH10B 6060769 YP_001729861.1 CDS clpA NC_010473.1 976415 978691 D ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 976415..978691 Escherichia coli str. K-12 substr. DH10B 6060764 YP_001729862.1 CDS infA NC_010473.1 979376 979594 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(979376..979594) Escherichia coli str. K-12 substr. DH10B 6059392 YP_001729863.1 CDS aat NC_010473.1 979879 980583 R leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase complement(979879..980583) Escherichia coli str. K-12 substr. DH10B 6060751 YP_001729864.1 CDS cydC NC_010473.1 980625 982346 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(980625..982346) Escherichia coli str. K-12 substr. DH10B 6060747 YP_001729865.1 CDS cydD NC_010473.1 982347 984113 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(982347..984113) Escherichia coli str. K-12 substr. DH10B 6060755 YP_001729866.1 CDS trxB NC_010473.1 984236 985201 R catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase complement(984236..985201) Escherichia coli str. K-12 substr. DH10B 6060711 YP_001729867.1 CDS lrp NC_010473.1 985746 986240 D mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 985746..986240 Escherichia coli str. K-12 substr. DH10B 6060741 YP_001729868.1 CDS ftsK NC_010473.1 986375 990364 D DNA-binding membrane protein required for chromosome resolution and partitioning; DNA translocase FtsK 986375..990364 Escherichia coli str. K-12 substr. DH10B 6060702 YP_001729869.1 CDS lolA NC_010473.1 990523 991134 D participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 990523..991134 Escherichia coli str. K-12 substr. DH10B 6060745 YP_001729870.1 CDS ycaJ NC_010473.1 991145 992488 D recombination factor protein RarA 991145..992488 Escherichia coli str. K-12 substr. DH10B 6060771 YP_001729871.1 CDS serS NC_010473.1 992579 993871 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 992579..993871 Escherichia coli str. K-12 substr. DH10B 6060765 YP_001729872.1 CDS dmsA NC_010473.1 994110 996554 D dimethyl sulfoxide reductase, anaerobic subunit A 994110..996554 Escherichia coli str. K-12 substr. DH10B 6060687 YP_001729873.1 CDS dmsB NC_010473.1 996565 997182 D dimethyl sulfoxide reductase, anaerobic subunit B 996565..997182 Escherichia coli str. K-12 substr. DH10B 6060692 YP_001729874.1 CDS dmsC NC_010473.1 997184 998047 D dimethyl sulfoxide reductase, anaerobic subunit C 997184..998047 Escherichia coli str. K-12 substr. DH10B 6060685 YP_001729875.1 CDS ycaC NC_010473.1 998082 998708 R hydrolase complement(998082..998708) Escherichia coli str. K-12 substr. DH10B 6060686 YP_001729876.1 CDS ycaD NC_010473.1 999022 1000170 D putative MFS family transporter protein 999022..1000170 Escherichia coli str. K-12 substr. DH10B 6060700 YP_001729877.1 CDS ycaM NC_010473.1 1000380 1001810 D transporter 1000380..1001810 Escherichia coli str. K-12 substr. DH10B 6060668 YP_001729878.1 CDS ycaN NC_010473.1 1001811 1002719 R DNA-binding transcriptional regulator complement(1001811..1002719) Escherichia coli str. K-12 substr. DH10B 6060656 YP_001729879.1 CDS ycaK NC_010473.1 1002819 1003409 D hypothetical protein 1002819..1003409 Escherichia coli str. K-12 substr. DH10B 6060658 YP_001729880.1 CDS pflA NC_010473.1 1003491 1004231 R activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 complement(1003491..1004231) Escherichia coli str. K-12 substr. DH10B 6060644 YP_001729881.1 CDS pflB NC_010473.1 1004423 1006705 R pyruvate formate lyase I complement(1004423..1006705) Escherichia coli str. K-12 substr. DH10B 6060638 YP_001729882.1 CDS focA NC_010473.1 1006760 1007617 R formate transporter complement(1006760..1007617) Escherichia coli str. K-12 substr. DH10B 6060640 YP_001729883.1 CDS ycaO NC_010473.1 1008023 1009783 R hypothetical protein complement(1008023..1009783) Escherichia coli str. K-12 substr. DH10B 6060634 YP_001729884.1 CDS ycaP NC_010473.1 1009913 1010605 D inner membrane protein 1009913..1010605 Escherichia coli str. K-12 substr. DH10B 6060641 YP_001729885.1 CDS serC NC_010473.1 1010804 1011892 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1010804..1011892 Escherichia coli str. K-12 substr. DH10B 6060653 YP_001729886.1 CDS aroA NC_010473.1 1011963 1013246 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1011963..1013246 Escherichia coli str. K-12 substr. DH10B 6060621 YP_001729887.1 CDS ycaL NC_010473.1 1013415 1014179 D peptidase with chaperone function 1013415..1014179 Escherichia coli str. K-12 substr. DH10B 6060626 YP_001729888.1 CDS cmk NC_010473.1 1014352 1015035 D Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1014352..1015035 Escherichia coli str. K-12 substr. DH10B 6060620 YP_001729889.1 CDS rpsA NC_010473.1 1015146 1016819 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1015146..1016819 Escherichia coli str. K-12 substr. DH10B 6060632 YP_001729890.1 CDS ihfB NC_010473.1 1016979 1017263 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1016979..1017263 Escherichia coli str. K-12 substr. DH10B 6060662 YP_001729891.1 CDS ycaI NC_010473.1 1017471 1019735 D hypothetical protein 1017471..1019735 Escherichia coli str. K-12 substr. DH10B 6060650 YP_001729892.1 CDS msbA NC_010473.1 1019772 1021520 D involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease 1019772..1021520 Escherichia coli str. K-12 substr. DH10B 6062280 YP_001729893.1 CDS lpxK NC_010473.1 1021517 1022503 D transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 1021517..1022503 Escherichia coli str. K-12 substr. DH10B 6060588 YP_001729894.1 CDS ycaQ NC_010473.1 1022540 1023772 D hypothetical protein 1022540..1023772 Escherichia coli str. K-12 substr. DH10B 6060592 YP_001729895.1 CDS ycaR NC_010473.1 1023824 1024006 D hypothetical protein 1023824..1024006 Escherichia coli str. K-12 substr. DH10B 6060583 YP_001729896.1 CDS kdsB NC_010473.1 1024003 1024749 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 1024003..1024749 Escherichia coli str. K-12 substr. DH10B 6060586 YP_001729897.1 CDS ycbJ NC_010473.1 1024903 1025796 D hypothetical protein 1024903..1025796 Escherichia coli str. K-12 substr. DH10B 6060612 YP_001729898.1 CDS ycbC NC_010473.1 1025773 1026552 R hypothetical protein complement(1025773..1026552) Escherichia coli str. K-12 substr. DH10B 6060581 YP_001729899.1 CDS smtA NC_010473.1 1026688 1027473 D involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; putative metallothionein SmtA 1026688..1027473 Escherichia coli str. K-12 substr. DH10B 6060571 YP_001729900.1 CDS mukF NC_010473.1 1027470 1028792 D acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 1027470..1028792 Escherichia coli str. K-12 substr. DH10B 6060574 YP_001729901.1 CDS mukE NC_010473.1 1028800 1029477 D protein involved in chromosome partitioning; acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 1028800..1029477 Escherichia coli str. K-12 substr. DH10B 6060563 YP_001729902.1 CDS mukB NC_010473.1 1029477 1033937 D SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 1029477..1033937 Escherichia coli str. K-12 substr. DH10B 6060547 YP_001729903.1 CDS ycbB NC_010473.1 1034198 1036045 D hypothetical protein 1034198..1036045 Escherichia coli str. K-12 substr. DH10B 6060557 YP_001729904.1 CDS ycbK NC_010473.1 1036226 1036774 D hypothetical protein 1036226..1036774 Escherichia coli str. K-12 substr. DH10B 6060546 YP_001729905.1 CDS ycbL NC_010473.1 1036801 1037448 D metal-binding protein 1036801..1037448 Escherichia coli str. K-12 substr. DH10B 6060562 YP_001729906.1 CDS aspC NC_010473.1 1037670 1038860 R catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase complement(1037670..1038860) Escherichia coli str. K-12 substr. DH10B 6060534 YP_001729907.1 CDS ompF NC_010473.1 1039045 1040133 R outer membrane porin F; 1a; Ia; b; outer membrane protein F complement(1039045..1040133) Escherichia coli str. K-12 substr. DH10B 6060536 YP_001729908.1 CDS asnC NC_010473.1 1040736 1042136 R catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase complement(1040736..1042136) Escherichia coli str. K-12 substr. DH10B 6060533 YP_001729909.1 CDS pncB NC_010473.1 1042305 1043507 R catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(1042305..1043507) Escherichia coli str. K-12 substr. DH10B 6060538 YP_001729910.1 CDS pepN NC_010473.1 1043773 1046385 D aminopeptidase N 1043773..1046385 Escherichia coli str. K-12 substr. DH10B 6060577 YP_001729911.1 CDS ssuB NC_010473.1 1046428 1047195 R part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit complement(1046428..1047195) Escherichia coli str. K-12 substr. DH10B 6060568 YP_001729912.1 CDS ssuC NC_010473.1 1047192 1047983 R part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease complement(1047192..1047983) Escherichia coli str. K-12 substr. DH10B 6060509 YP_001729913.1 CDS ssuD NC_010473.1 1047994 1049139 R catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase complement(1047994..1049139) Escherichia coli str. K-12 substr. DH10B 6060526 YP_001729914.1 CDS ssuA NC_010473.1 1049136 1050095 R part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit complement(1049136..1050095) Escherichia coli str. K-12 substr. DH10B 6060500 YP_001729915.1 CDS ssuE NC_010473.1 1050088 1050663 R NAD(P)H-dependent FMN reductase complement(1050088..1050663) Escherichia coli str. K-12 substr. DH10B 6060504 YP_001729916.1 CDS ycbQ NC_010473.1 1051019 1051558 D fimbrial-like adhesin protein 1051019..1051558 Escherichia coli str. K-12 substr. DH10B 6060532 YP_001729917.1 CDS ycbR NC_010473.1 1051641 1052342 D periplasmic pilin chaperone 1051641..1052342 Escherichia coli str. K-12 substr. DH10B 6060476 YP_001729918.1 CDS ycbS NC_010473.1 1052367 1054967 D outer membrane usher protein 1052367..1054967 Escherichia coli str. K-12 substr. DH10B 6060461 YP_001729919.1 CDS ycbT NC_010473.1 1054958 1056028 D fimbrial-like adhesin protein 1054958..1056028 Escherichia coli str. K-12 substr. DH10B 6060463 YP_001729920.1 CDS ycbU NC_010473.1 1056040 1056582 D contains the nonsynonymous change G119W; fimbrial-like adhesin protein 1056040..1056582 Escherichia coli str. K-12 substr. DH10B 6060380 YP_001729921.1 CDS ycbV NC_010473.1 1056590 1057105 D fimbrial-like adhesin protein 1056590..1057105 Escherichia coli str. K-12 substr. DH10B 6060374 YP_001729922.1 CDS ycbF NC_010473.1 1057098 1057808 D pili assembly chaperone 1057098..1057808 Escherichia coli str. K-12 substr. DH10B 6060375 YP_001729923.1 CDS pyrD NC_010473.1 1057919 1058929 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1057919..1058929 Escherichia coli str. K-12 substr. DH10B 6060372 YP_001729924.1 CDS ycbW NC_010473.1 1059103 1059645 D hypothetical protein 1059103..1059645 Escherichia coli str. K-12 substr. DH10B 6060379 YP_001729925.1 CDS ycbX NC_010473.1 1059642 1060751 R 2Fe-2S cluster-containing protein complement(1059642..1060751) Escherichia coli str. K-12 substr. DH10B 6060340 YP_001729926.1 CDS rlmL NC_010473.1 1060995 1063103 D catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1060995..1063103 Escherichia coli str. K-12 substr. DH10B 6060358 YP_001729927.1 CDS uup NC_010473.1 1063115 1065022 D Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1063115..1065022 Escherichia coli str. K-12 substr. DH10B 6060338 YP_001729928.1 CDS pqiA NC_010473.1 1065152 1066405 D paraquat-inducible membrane protein A 1065152..1066405 Escherichia coli str. K-12 substr. DH10B 6060365 YP_001729929.1 CDS pqiB NC_010473.1 1066410 1068050 D paraquat-inducible protein B 1066410..1068050 Escherichia coli str. K-12 substr. DH10B 6060396 YP_001729930.1 CDS ymbA NC_010473.1 1068047 1068610 D hypothetical protein 1068047..1068610 Escherichia coli str. K-12 substr. DH10B 6060464 YP_001729931.1 CDS rmf NC_010473.1 1068866 1069033 D ribosome modulation factor 1068866..1069033 Escherichia coli str. K-12 substr. DH10B 6060400 YP_001729932.1 CDS fabA NC_010473.1 1069103 1069621 R catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase complement(1069103..1069621) Escherichia coli str. K-12 substr. DH10B 6060334 YP_001729933.1 CDS ycbZ NC_010473.1 1069690 1071450 R peptidase complement(1069690..1071450) Escherichia coli str. K-12 substr. DH10B 6060335 YP_001729934.1 CDS ycbG NC_010473.1 1071636 1072088 D hypothetical protein 1071636..1072088 Escherichia coli str. K-12 substr. DH10B 6060326 YP_001729935.1 CDS ompA NC_010473.1 1072164 1073204 R OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A complement(1072164..1073204) Escherichia coli str. K-12 substr. DH10B 6060328 YP_001729936.1 CDS sulA NC_010473.1 1073561 1074070 R SOS cell division inhibitor complement(1073561..1074070) Escherichia coli str. K-12 substr. DH10B 6060336 YP_001729937.1 CDS sxy NC_010473.1 1074289 1074918 D CRP-S promoter co-activator 1074289..1074918 Escherichia coli str. K-12 substr. DH10B 6060320 YP_001729938.1 CDS yccS NC_010473.1 1074881 1077034 R inner membrane protein complement(1074881..1077034) Escherichia coli str. K-12 substr. DH10B 6060293 YP_001729939.1 CDS yccF NC_010473.1 1077053 1077499 R hypothetical protein complement(1077053..1077499) Escherichia coli str. K-12 substr. DH10B 6060300 YP_001729940.1 CDS helD NC_010473.1 1077622 1079676 D catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1077622..1079676 Escherichia coli str. K-12 substr. DH10B 6060264 YP_001729941.1 CDS mgsA NC_010473.1 1079708 1080166 R catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase complement(1079708..1080166) Escherichia coli str. K-12 substr. DH10B 6060225 YP_001729942.1 CDS yccT NC_010473.1 1080262 1080924 R hypothetical protein complement(1080262..1080924) Escherichia coli str. K-12 substr. DH10B 6060250 YP_001729943.1 CDS yccU NC_010473.1 1081097 1081510 D CoA-binding protein 1081097..1081510 Escherichia coli str. K-12 substr. DH10B 6060224 YP_001729944.1 CDS hspQ NC_010473.1 1081555 1081872 R heat shock protein HspQ complement(1081555..1081872) Escherichia coli str. K-12 substr. DH10B 6060257 YP_001729945.1 CDS yccW NC_010473.1 1081930 1083120 R methyltransferase complement(1081930..1083120) Escherichia coli str. K-12 substr. DH10B 6060205 YP_001729946.1 CDS yccX NC_010473.1 1083215 1083493 D catalyzes the hydrolysis of acylphosphate; acylphosphatase 1083215..1083493 Escherichia coli str. K-12 substr. DH10B 6060211 YP_001729947.1 CDS yccK NC_010473.1 1083490 1083819 R transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE complement(1083490..1083819) Escherichia coli str. K-12 substr. DH10B 6060203 YP_001729948.1 CDS yccA NC_010473.1 1083910 1084569 R hypothetical protein complement(1083910..1084569) Escherichia coli str. K-12 substr. DH10B 6060215 YP_001729949.1 CDS hyaA NC_010473.1 1085290 1086408 D hydrogenase 1, small subunit 1085290..1086408 Escherichia coli str. K-12 substr. DH10B 6060551 YP_001729950.1 CDS hyaB NC_010473.1 1086405 1088198 D involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 1086405..1088198 Escherichia coli str. K-12 substr. DH10B 6060289 YP_001729951.1 CDS hyaC NC_010473.1 1088217 1088924 D hydrogenase 1 b-type cytochrome subunit 1088217..1088924 Escherichia coli str. K-12 substr. DH10B 6060173 YP_001729952.1 CDS hyaD NC_010473.1 1088921 1089508 D protein involved in processing of HyaA and HyaB proteins; HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 1088921..1089508 Escherichia coli str. K-12 substr. DH10B 6060182 YP_001729953.1 CDS hyaE NC_010473.1 1089505 1089903 D protein involved in processing of HyaA and HyaB proteins; involved in processing hydrogenase proteins HyaA and HyaB; hydrogenase-1 operon protein HyaE 1089505..1089903 Escherichia coli str. K-12 substr. DH10B 6060159 YP_001729954.1 CDS hyaF NC_010473.1 1089900 1090757 D protein involved in nickel incorporation into hydrogenase-1 proteins; protein HyaF 1089900..1090757 Escherichia coli str. K-12 substr. DH10B 6060164 YP_001729955.1 CDS appC NC_010473.1 1090891 1092435 D cytochrome bd-II oxidase subunit I 1090891..1092435 Escherichia coli str. K-12 substr. DH10B 6060199 YP_001729956.1 CDS appB NC_010473.1 1092447 1093583 D contains synonymous changes in codon 277; cytochrome bd-II oxidase subunit II 1092447..1093583 Escherichia coli str. K-12 substr. DH10B 6060155 YP_001729957.1 CDS appA NC_010473.1 1093768 1095066 D phosphoanhydride phosphorylase 1093768..1095066 Escherichia coli str. K-12 substr. DH10B 6060145 YP_001729958.1 CDS etk NC_010473.1 1095181 1097361 R cryptic autophosphorylating protein tyrosine kinase Etk complement(1095181..1097361) Escherichia coli str. K-12 substr. DH10B 6060149 YP_001729959.1 CDS etp NC_010473.1 1097381 1097827 R Etk and Etp are a tyrosine kinase-tyrosine phosphatase pair, etp dephosphorylates etk; phosphotyrosine-protein phosphatase complement(1097381..1097827) Escherichia coli str. K-12 substr. DH10B 6060138 YP_001729960.1 CDS gfcE NC_010473.1 1097815 1098954 R exopolysaccharide export protein complement(1097815..1098954) Escherichia coli str. K-12 substr. DH10B 6060104 YP_001729961.1 CDS gfcD NC_010473.1 1099000 1101096 R hypothetical protein complement(1099000..1101096) Escherichia coli str. K-12 substr. DH10B 6060113 YP_001729962.1 CDS gfcC NC_010473.1 1101096 1101842 R hypothetical protein complement(1101096..1101842) Escherichia coli str. K-12 substr. DH10B 6060054 YP_001729963.1 CDS gfcB NC_010473.1 1101839 1102483 R outer membrane lipoprotein complement(1101839..1102483) Escherichia coli str. K-12 substr. DH10B 6060125 YP_001729964.1 CDS gfcA NC_010473.1 1102590 1102895 R hypothetical protein complement(1102590..1102895) Escherichia coli str. K-12 substr. DH10B 6059948 YP_001729965.1 CDS insA-4 NC_010473.1 1102984 1103259 D IS1 repressor protein InsA 1102984..1103259 Escherichia coli str. K-12 substr. DH10B 6059974 YP_001729966.1 CDS insB-4 NC_010473.1 1103178 1103681 D IS1 transposase InsAB' 1103178..1103681 Escherichia coli str. K-12 substr. DH10B 6059912 YP_001729967.1 CDS cspH NC_010473.1 1104114 1104326 R CspA family stress protein complement(1104114..1104326) Escherichia coli str. K-12 substr. DH10B 6059997 YP_001729968.1 CDS cspG NC_010473.1 1104612 1104824 D cold shock protein CspG 1104612..1104824 Escherichia coli str. K-12 substr. DH10B 6060151 YP_001729969.1 CDS ymcE NC_010473.1 1104998 1105228 D cold shock gene 1104998..1105228 Escherichia coli str. K-12 substr. DH10B 6060144 YP_001729970.1 CDS gnsA NC_010473.1 1105218 1105391 D regulator of phosphatidylethanolamine synthesis 1105218..1105391 Escherichia coli str. K-12 substr. DH10B 6059896 YP_001729971.1 CDS yccM NC_010473.1 1105440 1106513 R 4Fe-4S binding protein complement(1105440..1106513) Escherichia coli str. K-12 substr. DH10B 6059908 YP_001729972.1 CDS torS NC_010473.1 1106585 1109329 R Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS complement(1106585..1109329) Escherichia coli str. K-12 substr. DH10B 6059859 YP_001729973.1 CDS torT NC_010473.1 1109412 1110440 D periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 1109412..1110440 Escherichia coli str. K-12 substr. DH10B 6059865 YP_001729974.1 CDS torR NC_010473.1 1110413 1111105 R response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR complement(1110413..1111105) Escherichia coli str. K-12 substr. DH10B 6059909 YP_001729975.1 CDS torC NC_010473.1 1111235 1112407 D trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit 1111235..1112407 Escherichia coli str. K-12 substr. DH10B 6059809 YP_001729976.1 CDS torA NC_010473.1 1112407 1114953 D trimethylamine N-oxide (TMAO) reductase I, catalytic subunit 1112407..1114953 Escherichia coli str. K-12 substr. DH10B 6059739 YP_001729977.1 CDS torD NC_010473.1 1114950 1115549 D TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1114950..1115549 Escherichia coli str. K-12 substr. DH10B 6059752 YP_001729978.1 CDS cbpM NC_010473.1 1115701 1116006 R with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM complement(1115701..1116006) Escherichia coli str. K-12 substr. DH10B 6059720 YP_001729979.1 CDS cbpA NC_010473.1 1116006 1116926 R DnaJ-like protein that functions as a co-chaperone of DnaK; functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA complement(1116006..1116926) Escherichia coli str. K-12 substr. DH10B 6059667 YP_001729980.1 CDS yccE NC_010473.1 1117187 1118443 D hypothetical protein 1117187..1118443 Escherichia coli str. K-12 substr. DH10B 6059689 YP_001729981.1 CDS agp NC_010473.1 1118736 1119977 D glucose-1-phosphatase/inositol phosphatase 1118736..1119977 Escherichia coli str. K-12 substr. DH10B 6059655 YP_001729982.1 CDS yccJ NC_010473.1 1120015 1120242 R hypothetical protein complement(1120015..1120242) Escherichia coli str. K-12 substr. DH10B 6059713 YP_001729983.1 CDS wrbA NC_010473.1 1120263 1120859 R stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA complement(1120263..1120859) Escherichia coli str. K-12 substr. DH10B 6059642 YP_001729984.1 CDS ymdF NC_010473.1 1121232 1121405 D hypothetical protein 1121232..1121405 Escherichia coli str. K-12 substr. DH10B 6059645 YP_001729985.1 CDS rutG NC_010473.1 1121662 1122990 R pyrimidine transporter complement(1121662..1122990) Escherichia coli str. K-12 substr. DH10B 6059615 YP_001729986.1 CDS rutF NC_010473.1 1123011 1123505 R oxidoreductase, flavin:NADH component complement(1123011..1123505) Escherichia coli str. K-12 substr. DH10B 6059652 YP_001729987.1 CDS rutE NC_010473.1 1123516 1124106 R hypothetical protein complement(1123516..1124106) Escherichia coli str. K-12 substr. DH10B 6059777 YP_001729988.1 CDS rutD NC_010473.1 1124116 1124916 R hydrolase complement(1124116..1124916) Escherichia coli str. K-12 substr. DH10B 6059721 YP_001729989.1 CDS rutC NC_010473.1 1124924 1125310 R hypothetical protein complement(1124924..1125310) Escherichia coli str. K-12 substr. DH10B 6059549 YP_001729990.1 CDS rutB NC_010473.1 1125322 1126014 R isochorismatase complement(1125322..1126014) Escherichia coli str. K-12 substr. DH10B 6059552 YP_001729991.1 CDS rutA NC_010473.1 1126014 1127162 R monooxygenase complement(1126014..1127162) Escherichia coli str. K-12 substr. DH10B 6059490 YP_001729992.1 CDS rutR NC_010473.1 1127393 1128031 D rut operon repressor 1127393..1128031 Escherichia coli str. K-12 substr. DH10B 6059538 YP_001729993.1 CDS putA NC_010473.1 1128071 1132033 R proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase complement(1128071..1132033) Escherichia coli str. K-12 substr. DH10B 6059557 YP_001729994.1 CDS putP NC_010473.1 1132456 1133964 D proline:sodium symporter 1132456..1133964 Escherichia coli str. K-12 substr. DH10B 6059483 YP_001729995.1 CDS efeO NC_010473.1 1135394 1136521 D hypothetical protein 1135394..1136521 Escherichia coli str. K-12 substr. DH10B 6061324 YP_001729996.1 CDS efeB NC_010473.1 1136527 1137798 D redox component of a tripartite ferrous iron transporter 1136527..1137798 Escherichia coli str. K-12 substr. DH10B 6059455 YP_001729997.1 CDS phoH NC_010473.1 1138143 1139207 D hypothetical protein 1138143..1139207 Escherichia coli str. K-12 substr. DH10B 6059431 YP_001729998.1 CDS pgaD NC_010473.1 1139257 1139670 R in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export; putative PGA biosynthesis protein complement(1139257..1139670) Escherichia coli str. K-12 substr. DH10B 6059410 YP_001729999.1 CDS pgaC NC_010473.1 1139672 1140997 R predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase complement(1139672..1140997) Escherichia coli str. K-12 substr. DH10B 6059425 YP_001730000.1 CDS pgaB NC_010473.1 1140990 1143008 R in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export; outer membrane N-deacetylase complement(1140990..1143008) Escherichia coli str. K-12 substr. DH10B 6059405 YP_001730001.1 CDS pgaA NC_010473.1 1143017 1145440 R outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA complement(1143017..1145440) Escherichia coli str. K-12 substr. DH10B 6059428 YP_001730002.1 CDS insF-4 NC_010473.1 1148762 1149628 R IS3 element protein InsF complement(1148762..1149628) Escherichia coli str. K-12 substr. DH10B 6062272 YP_001730003.1 CDS insE-4 NC_010473.1 1149625 1149933 R IS3 element protein InsE complement(1149625..1149933) Escherichia coli str. K-12 substr. DH10B 6059377 YP_001730004.1 CDS ycdU NC_010473.1 1150330 1151316 D inner membrane protein 1150330..1151316 Escherichia coli str. K-12 substr. DH10B 6059062 YP_001730005.1 CDS ycdW NC_010473.1 1152554 1153492 D 2-ketoacid reductase 1152554..1153492 Escherichia coli str. K-12 substr. DH10B 6060511 YP_001730006.1 CDS ycdX NC_010473.1 1153547 1154284 D putative hydrolase 1153547..1154284 Escherichia coli str. K-12 substr. DH10B 6059470 YP_001730007.1 CDS ycdY NC_010473.1 1154308 1154862 D contains the nonsynonymous change C144Y; hypothetical protein 1154308..1154862 Escherichia coli str. K-12 substr. DH10B 6059439 YP_001730008.1 CDS ycdZ NC_010473.1 1154964 1155455 D inner membrane protein 1154964..1155455 Escherichia coli str. K-12 substr. DH10B 6059338 YP_001730009.1 CDS csgG NC_010473.1 1155519 1156352 R outer membrane channel lipoprotein complement(1155519..1156352) Escherichia coli str. K-12 substr. DH10B 6059346 YP_001730010.1 CDS csgF NC_010473.1 1156379 1156795 R nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF complement(1156379..1156795) Escherichia coli str. K-12 substr. DH10B 6059299 YP_001730011.1 CDS csgE NC_010473.1 1156820 1157209 R chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE complement(1156820..1157209) Escherichia coli str. K-12 substr. DH10B 6059336 YP_001730012.1 CDS csgD NC_010473.1 1157214 1157864 R activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD complement(1157214..1157864) Escherichia coli str. K-12 substr. DH10B 6059357 YP_001730013.1 CDS csgB NC_010473.1 1158619 1159074 D CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1158619..1159074 Escherichia coli str. K-12 substr. DH10B 6059298 YP_001730014.1 CDS csgA NC_010473.1 1159115 1159570 D cryptic curlin major subunit 1159115..1159570 Escherichia coli str. K-12 substr. DH10B 6059265 YP_001730015.1 CDS csgC NC_010473.1 1159629 1159961 D involved in autoagglutination of curliated cells; not involved in production of curli fibers; putative autoagglutination protein 1159629..1159961 Escherichia coli str. K-12 substr. DH10B 6059266 YP_001730016.1 CDS ymdA NC_010473.1 1160082 1160393 D hypothetical protein 1160082..1160393 Escherichia coli str. K-12 substr. DH10B 6059241 YP_001730017.1 CDS ymdB NC_010473.1 1160488 1161021 D hypothetical protein 1160488..1161021 Escherichia coli str. K-12 substr. DH10B 6059212 YP_001730018.1 CDS ymdC NC_010473.1 1161023 1162444 D hydrolase 1161023..1162444 Escherichia coli str. K-12 substr. DH10B 6059214 YP_001730019.1 CDS mdoC NC_010473.1 1162452 1163609 R required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein complement(1162452..1163609) Escherichia coli str. K-12 substr. DH10B 6059204 YP_001730020.1 CDS mdoG NC_010473.1 1164003 1165538 D involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1164003..1165538 Escherichia coli str. K-12 substr. DH10B 6059215 YP_001730021.1 CDS mdoH NC_010473.1 1165531 1168074 D necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1165531..1168074 Escherichia coli str. K-12 substr. DH10B 6059174 YP_001730022.1 CDS yceK NC_010473.1 1168247 1168474 D hypothetical protein 1168247..1168474 Escherichia coli str. K-12 substr. DH10B 6059188 YP_001730023.1 CDS msyB NC_010473.1 1168475 1168849 R hypothetical protein complement(1168475..1168849) Escherichia coli str. K-12 substr. DH10B 6059171 YP_001730024.1 CDS mdtG NC_010473.1 1168932 1170158 R Confers resistance to fosfomycin and deoxycholate; drug efflux system protein MdtG complement(1168932..1170158) Escherichia coli str. K-12 substr. DH10B 6059189 YP_001730025.1 CDS lpxL NC_010473.1 1170330 1171250 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(1170330..1171250) Escherichia coli str. K-12 substr. DH10B 6059293 YP_001730026.1 CDS yceA NC_010473.1 1171475 1172527 D hypothetical protein 1171475..1172527 Escherichia coli str. K-12 substr. DH10B 6059244 YP_001730027.1 CDS yceI NC_010473.1 1172569 1173144 R hypothetical protein complement(1172569..1173144) Escherichia coli str. K-12 substr. DH10B 6059386 YP_001730028.1 CDS yceJ NC_010473.1 1173148 1173714 R cytochrome b561 complement(1173148..1173714) Escherichia coli str. K-12 substr. DH10B 6059115 YP_001730029.1 CDS yceO NC_010473.1 1173975 1174115 R hypothetical protein complement(1173975..1174115) Escherichia coli str. K-12 substr. DH10B 6059145 YP_001730030.1 CDS solA NC_010473.1 1174136 1175254 R catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase complement(1174136..1175254) Escherichia coli str. K-12 substr. DH10B 6059108 YP_001730031.1 CDS bssS NC_010473.1 1175369 1175623 R BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS complement(1175369..1175623) Escherichia coli str. K-12 substr. DH10B 6059109 YP_001730032.1 CDS dinI NC_010473.1 1175910 1176155 R DNA damage-inducible protein I complement(1175910..1176155) Escherichia coli str. K-12 substr. DH10B 6059150 YP_001730033.1 CDS pyrC NC_010473.1 1176229 1177275 R catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase complement(1176229..1177275) Escherichia coli str. K-12 substr. DH10B 6059070 YP_001730034.1 CDS yceB NC_010473.1 1177381 1177941 R hypothetical protein complement(1177381..1177941) Escherichia coli str. K-12 substr. DH10B 6059047 YP_001730035.1 CDS grxB NC_010473.1 1178075 1178722 R cofactor involved in the reduction of disulfides; glutaredoxin complement(1178075..1178722) Escherichia coli str. K-12 substr. DH10B 6059059 YP_001730036.1 CDS mdtH NC_010473.1 1178786 1179994 R Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH complement(1178786..1179994) Escherichia coli str. K-12 substr. DH10B 6059039 YP_001730037.1 CDS rimJ NC_010473.1 1180230 1180814 D ribosomal-protein-S5-alanine N-acetyltransferase 1180230..1180814 Escherichia coli str. K-12 substr. DH10B 6059016 YP_001730038.1 CDS yceH NC_010473.1 1180825 1181472 D hypothetical protein 1180825..1181472 Escherichia coli str. K-12 substr. DH10B 6059031 YP_001730039.1 CDS mviM NC_010473.1 1181474 1182397 D oxidoreductase 1181474..1182397 Escherichia coli str. K-12 substr. DH10B 6059010 YP_001730040.1 CDS yceN NC_010473.1 1182507 1184042 D inner membrane protein 1182507..1184042 Escherichia coli str. K-12 substr. DH10B 6059037 YP_001730041.1 CDS flgN NC_010473.1 1184082 1184498 R export chaperone for FlgK and FlgL complement(1184082..1184498) Escherichia coli str. K-12 substr. DH10B 6059005 YP_001730042.1 CDS flgM NC_010473.1 1184503 1184796 R regulates the flagellar specific sigma28 transcription factor; anti-sigma-28 factor FlgM complement(1184503..1184796) Escherichia coli str. K-12 substr. DH10B 6059007 YP_001730043.1 CDS flgA NC_010473.1 1184872 1185531 R required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA complement(1184872..1185531) Escherichia coli str. K-12 substr. DH10B 6058997 YP_001730044.1 CDS flgB NC_010473.1 1185686 1186102 D with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB 1185686..1186102 Escherichia coli str. K-12 substr. DH10B 6059008 YP_001730045.1 CDS flgC NC_010473.1 1186106 1186510 D with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1186106..1186510 Escherichia coli str. K-12 substr. DH10B 6059068 YP_001730046.1 CDS flgD NC_010473.1 1186522 1187217 D acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1186522..1187217 Escherichia coli str. K-12 substr. DH10B 6059040 YP_001730047.1 CDS flgE NC_010473.1 1187242 1188450 D the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1187242..1188450 Escherichia coli str. K-12 substr. DH10B 6058938 YP_001730048.1 CDS flgF NC_010473.1 1188470 1189225 D FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1188470..1189225 Escherichia coli str. K-12 substr. DH10B 6058953 YP_001730049.1 CDS flgG NC_010473.1 1189397 1190179 D makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1189397..1190179 Escherichia coli str. K-12 substr. DH10B 6058919 YP_001730050.1 CDS flgH NC_010473.1 1190232 1190930 D part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1190232..1190930 Escherichia coli str. K-12 substr. DH10B 6058922 YP_001730051.1 CDS flgI NC_010473.1 1190942 1192039 D part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 1190942..1192039 Escherichia coli str. K-12 substr. DH10B 6058977 YP_001730052.1 CDS flgJ NC_010473.1 1192039 1192980 D Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1192039..1192980 Escherichia coli str. K-12 substr. DH10B 6058914 YP_001730053.1 CDS flgK NC_010473.1 1193046 1194689 D with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1193046..1194689 Escherichia coli str. K-12 substr. DH10B 6058889 YP_001730054.1 CDS flgL NC_010473.1 1194701 1195654 D with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1194701..1195654 Escherichia coli str. K-12 substr. DH10B 6058891 YP_001730055.1 CDS rne NC_010473.1 1195850 1199035 R bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E complement(1195850..1199035) Escherichia coli str. K-12 substr. DH10B 6058874 YP_001730056.1 CDS yceQ NC_010473.1 1199170 1199490 D hypothetical protein 1199170..1199490 Escherichia coli str. K-12 substr. DH10B 6058842 YP_001730057.1 CDS rluC NC_010473.1 1199608 1200567 D catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1199608..1200567 Escherichia coli str. K-12 substr. DH10B 6058855 YP_001730058.1 CDS yceF NC_010473.1 1200679 1201263 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(1200679..1201263) Escherichia coli str. K-12 substr. DH10B 6058836 YP_001730059.1 CDS yceD NC_010473.1 1201462 1201983 D hypothetical protein 1201462..1201983 Escherichia coli str. K-12 substr. DH10B 6061961 YP_001730060.1 CDS rpmF NC_010473.1 1202035 1202208 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1202035..1202208 Escherichia coli str. K-12 substr. DH10B 6058827 YP_001730061.1 CDS plsX NC_010473.1 1202289 1203359 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 1202289..1203359 Escherichia coli str. K-12 substr. DH10B 6058828 YP_001730062.1 CDS fabH NC_010473.1 1203427 1204380 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1203427..1204380 Escherichia coli str. K-12 substr. DH10B 6058821 YP_001730063.1 CDS fabD NC_010473.1 1204396 1205325 D malonyl-CoA-[acyl-carrier-protein] transacylase 1204396..1205325 Escherichia coli str. K-12 substr. DH10B 6058831 YP_001730064.1 CDS fabG NC_010473.1 1205338 1206072 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1205338..1206072 Escherichia coli str. K-12 substr. DH10B 6058893 YP_001730065.1 CDS acpP NC_010473.1 1206283 1206519 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1206283..1206519 Escherichia coli str. K-12 substr. DH10B 6058875 YP_001730066.1 CDS fabF NC_010473.1 1206607 1207848 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 1206607..1207848 Escherichia coli str. K-12 substr. DH10B 6058791 YP_001730067.1 CDS pabC NC_010473.1 1207968 1208777 D catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1207968..1208777 Escherichia coli str. K-12 substr. DH10B 6058792 YP_001730068.1 CDS yceG NC_010473.1 1208780 1209802 D hypothetical protein 1208780..1209802 Escherichia coli str. K-12 substr. DH10B 6058777 YP_001730069.1 CDS tmk NC_010473.1 1209792 1210433 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1209792..1210433 Escherichia coli str. K-12 substr. DH10B 6058785 YP_001730070.1 CDS holB NC_010473.1 1210430 1211434 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1210430..1211434 Escherichia coli str. K-12 substr. DH10B 6058796 YP_001730071.1 CDS ycfH NC_010473.1 1211445 1212242 D putative metallodependent hydrolase 1211445..1212242 Escherichia coli str. K-12 substr. DH10B 6058760 YP_001730072.1 CDS ptsG NC_010473.1 1212537 1213970 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunit IIBC 1212537..1213970 Escherichia coli str. K-12 substr. DH10B 6058738 YP_001730073.1 CDS fhuE NC_010473.1 1214030 1216219 R ferric-rhodotorulic acid outer membrane transporter complement(1214030..1216219) Escherichia coli str. K-12 substr. DH10B 6058740 YP_001730074.1 CDS hinT NC_010473.1 1216553 1216912 D purine nucleoside phosphoramidase 1216553..1216912 Escherichia coli str. K-12 substr. DH10B 6058735 YP_001730075.1 CDS ycfL NC_010473.1 1216915 1217292 D lipoprotein 1216915..1217292 Escherichia coli str. K-12 substr. DH10B 6058711 YP_001730076.1 CDS ycfM NC_010473.1 1217306 1217947 D outer membrane lipoprotein 1217306..1217947 Escherichia coli str. K-12 substr. DH10B 6058731 YP_001730077.1 CDS thiK NC_010473.1 1217928 1218752 D catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1217928..1218752 Escherichia coli str. K-12 substr. DH10B 6058697 YP_001730078.1 CDS nagZ NC_010473.1 1218763 1219788 D hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1218763..1219788 Escherichia coli str. K-12 substr. DH10B 6058733 YP_001730079.1 CDS ycfP NC_010473.1 1219811 1220353 D hypothetical protein 1219811..1220353 Escherichia coli str. K-12 substr. DH10B 6058670 YP_001730080.1 CDS ndh NC_010473.1 1220753 1222057 D respiratory NADH dehydrogenase 2/cupric reductase 1220753..1222057 Escherichia coli str. K-12 substr. DH10B 6058686 YP_001730081.1 CDS ycfJ NC_010473.1 1222267 1222806 D hypothetical protein 1222267..1222806 Escherichia coli str. K-12 substr. DH10B 6058668 YP_001730082.1 CDS ycfQ NC_010473.1 1222868 1223500 R DNA-binding transcriptional regulator complement(1222868..1223500) Escherichia coli str. K-12 substr. DH10B 6058691 YP_001730083.1 CDS ycfR NC_010473.1 1223741 1223998 D hypothetical protein 1223741..1223998 Escherichia coli str. K-12 substr. DH10B 6060652 YP_001730084.1 CDS ycfS NC_010473.1 1224080 1225042 R contains the nonsynonymous change L180P; hypothetical protein complement(1224080..1225042) Escherichia coli str. K-12 substr. DH10B 6058759 YP_001730085.1 CDS mfd NC_010473.1 1225186 1228632 R transcription-repair coupling factor complement(1225186..1228632) Escherichia coli str. K-12 substr. DH10B 6058736 YP_001730086.1 CDS ycfT NC_010473.1 1228760 1229833 R inner membrane protein complement(1228760..1229833) Escherichia coli str. K-12 substr. DH10B 6058642 YP_001730087.1 CDS lolC NC_010473.1 1230095 1231294 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1230095..1231294 Escherichia coli str. K-12 substr. DH10B 6058652 YP_001730088.1 CDS lolD NC_010473.1 1231287 1231988 D outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1231287..1231988 Escherichia coli str. K-12 substr. DH10B 6058630 YP_001730089.1 CDS lolE NC_010473.1 1231988 1233232 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1231988..1233232 Escherichia coli str. K-12 substr. DH10B 6058638 YP_001730090.1 CDS nagK NC_010473.1 1233261 1234172 D catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1233261..1234172 Escherichia coli str. K-12 substr. DH10B 6058658 YP_001730091.1 CDS cobB NC_010473.1 1234188 1235027 D Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1234188..1235027 Escherichia coli str. K-12 substr. DH10B 6058617 YP_001730092.1 CDS ycfZ NC_010473.1 1235147 1235935 R inner membrane protein complement(1235147..1235935) Escherichia coli str. K-12 substr. DH10B 6058619 YP_001730093.1 CDS ymfA NC_010473.1 1235932 1236393 R inner membrane protein complement(1235932..1236393) Escherichia coli str. K-12 substr. DH10B 6058610 YP_001730094.1 CDS potD NC_010473.1 1236451 1237497 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter substrate-binding protein complement(1236451..1237497) Escherichia coli str. K-12 substr. DH10B 6058612 YP_001730095.1 CDS potC NC_010473.1 1237494 1238288 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1237494..1238288) Escherichia coli str. K-12 substr. DH10B 6058624 YP_001730096.1 CDS potB NC_010473.1 1238285 1239112 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1238285..1239112) Escherichia coli str. K-12 substr. DH10B 6058608 YP_001730097.1 CDS potA NC_010473.1 1239126 1240262 R functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase complement(1239126..1240262) Escherichia coli str. K-12 substr. DH10B 6058606 YP_001730098.1 CDS pepT NC_010473.1 1240512 1241738 D catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1240512..1241738 Escherichia coli str. K-12 substr. DH10B 6058603 YP_001730099.1 CDS ycfD NC_010473.1 1241787 1242908 R hypothetical protein complement(1241787..1242908) Escherichia coli str. K-12 substr. DH10B 6058604 YP_001730100.1 CDS phoQ NC_010473.1 1242984 1244444 R sensor protein PhoQ complement(1242984..1244444) Escherichia coli str. K-12 substr. DH10B 6058588 YP_001730101.1 CDS phoP NC_010473.1 1244444 1245115 R response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP complement(1244444..1245115) Escherichia coli str. K-12 substr. DH10B 6058593 YP_001730102.1 CDS purB NC_010473.1 1245284 1246654 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(1245284..1246654) Escherichia coli str. K-12 substr. DH10B 6058585 YP_001730103.1 CDS hflD NC_010473.1 1246658 1247299 R HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein complement(1246658..1247299) Escherichia coli str. K-12 substr. DH10B 6058581 YP_001730104.1 CDS mnmA NC_010473.1 1247335 1248441 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(1247335..1248441) Escherichia coli str. K-12 substr. DH10B 6058582 YP_001730105.1 CDS nudJ NC_010473.1 1248495 1248956 R bifunctional thiamin pyrimidine pyrophosphate hydrolase and thiamin pyrophosphate hydrolase complement(1248495..1248956) Escherichia coli str. K-12 substr. DH10B 6058579 YP_001730106.1 CDS rluE NC_010473.1 1248966 1249619 R catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E complement(1248966..1249619) Escherichia coli str. K-12 substr. DH10B 6058584 YP_001730107.1 CDS icd NC_010473.1 1249791 1251041 D Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1249791..1251041 Escherichia coli str. K-12 substr. DH10B 6058576 YP_001730108.1 CDS elbA NC_010473.1 1251144 1251467 R hypothetical protein complement(1251144..1251467) Escherichia coli str. K-12 substr. DH10B 6058577 YP_001730109.1 CDS ycgX NC_010473.1 1252167 1252571 R hypothetical protein complement(1252167..1252571) Escherichia coli str. K-12 substr. DH10B 6058575 YP_001730110.1 CDS ycgE NC_010473.1 1252792 1253523 R DNA-binding transcriptional regulator complement(1252792..1253523) Escherichia coli str. K-12 substr. DH10B 6058578 YP_001730111.1 CDS ycgF NC_010473.1 1253728 1254939 R FAD-binding phosphodiesterase complement(1253728..1254939) Escherichia coli str. K-12 substr. DH10B 6058571 YP_001730112.1 CDS ycgZ NC_010473.1 1255253 1255489 D hypothetical protein 1255253..1255489 Escherichia coli str. K-12 substr. DH10B 6058572 YP_001730113.1 CDS ymgA NC_010473.1 1255532 1255804 D hypothetical protein 1255532..1255804 Escherichia coli str. K-12 substr. DH10B 6058568 YP_001730114.1 CDS ymgB NC_010473.1 1255833 1256099 D hypothetical protein 1255833..1256099 Escherichia coli str. K-12 substr. DH10B 6058573 YP_001730115.1 CDS ymgC NC_010473.1 1256212 1256460 D hypothetical protein 1256212..1256460 Escherichia coli str. K-12 substr. DH10B 6058605 YP_001730116.1 CDS ycgG NC_010473.1 1256792 1258315 D inner membrane protein 1256792..1258315 Escherichia coli str. K-12 substr. DH10B 6058598 YP_001730117.1 CDS ymgF NC_010473.1 1258447 1258665 D hypothetical protein 1258447..1258665 Escherichia coli str. K-12 substr. DH10B 6060417 YP_001730118.1 CDS ymgD NC_010473.1 1261769 1262098 R hypothetical protein complement(1261769..1262098) Escherichia coli str. K-12 substr. DH10B 6062256 YP_001730119.1 CDS ymgG NC_010473.1 1262108 1262383 R hypothetical protein complement(1262108..1262383) Escherichia coli str. K-12 substr. DH10B 6060459 YP_001730120.1 CDS ymgI NC_010473.1 1262454 1262627 R hypothetical protein complement(1262454..1262627) Escherichia coli str. K-12 substr. DH10B 6060447 YP_001730121.1 CDS ymgJ NC_010473.1 1262728 1262913 D hypothetical protein 1262728..1262913 Escherichia coli str. K-12 substr. DH10B 6060446 YP_001730122.1 CDS minE NC_010473.1 1263743 1264009 R works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE complement(1263743..1264009) Escherichia coli str. K-12 substr. DH10B 6061217 YP_001730123.1 CDS minD NC_010473.1 1264013 1264825 R ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD complement(1264013..1264825) Escherichia coli str. K-12 substr. DH10B 6060438 YP_001730124.1 CDS minC NC_010473.1 1264849 1265544 R blocks the formation of polar Z-ring septums; septum formation inhibitor complement(1264849..1265544) Escherichia coli str. K-12 substr. DH10B 6060428 YP_001730125.1 CDS ycgJ NC_010473.1 1266064 1266432 D hypothetical protein 1266064..1266432 Escherichia coli str. K-12 substr. DH10B 6058594 YP_001730126.1 CDS ycgK NC_010473.1 1266535 1266936 R hypothetical protein complement(1266535..1266936) Escherichia coli str. K-12 substr. DH10B 6058586 YP_001730127.1 CDS ycgL NC_010473.1 1267145 1267471 D hypothetical protein 1267145..1267471 Escherichia coli str. K-12 substr. DH10B 6058562 YP_001730128.1 CDS ycgM NC_010473.1 1267543 1268202 D hypothetical protein 1267543..1268202 Escherichia coli str. K-12 substr. DH10B 6058564 YP_001730129.1 CDS ycgN NC_010473.1 1268279 1268740 D hypothetical protein 1268279..1268740 Escherichia coli str. K-12 substr. DH10B 6058557 YP_001730130.1 CDS hlyE NC_010473.1 1268947 1269858 R Acts by forming a pore-like structure upon contact with mammalian cells; hemolysin E complement(1268947..1269858) Escherichia coli str. K-12 substr. DH10B 6058558 YP_001730131.1 CDS umuD NC_010473.1 1270231 1270650 D binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1270231..1270650 Escherichia coli str. K-12 substr. DH10B 6058566 YP_001730132.1 CDS umuC NC_010473.1 1270650 1271918 D binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1270650..1271918 Escherichia coli str. K-12 substr. DH10B 6058556 YP_001730133.1 CDS dsbB NC_010473.1 1271964 1272494 R disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B complement(1271964..1272494) Escherichia coli str. K-12 substr. DH10B 6058550 YP_001730134.1 CDS nhaB NC_010473.1 1272640 1274181 R involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter complement(1272640..1274181) Escherichia coli str. K-12 substr. DH10B 6058552 YP_001730135.1 CDS fadR NC_010473.1 1274402 1275121 D Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1274402..1275121 Escherichia coli str. K-12 substr. DH10B 6058547 YP_001730136.1 CDS ycgB NC_010473.1 1275173 1276705 R SpoVR family protein complement(1275173..1276705) Escherichia coli str. K-12 substr. DH10B 6058539 YP_001730137.1 CDS dadA NC_010473.1 1277035 1278333 D catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1277035..1278333 Escherichia coli str. K-12 substr. DH10B 6058541 YP_001730138.1 CDS dadX NC_010473.1 1278343 1279413 D catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1278343..1279413 Escherichia coli str. K-12 substr. DH10B 6058538 YP_001730139.1 CDS cvrA NC_010473.1 1279799 1281535 R the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter complement(1279799..1281535) Escherichia coli str. K-12 substr. DH10B 6058546 YP_001730140.1 CDS ldcA NC_010473.1 1281630 1282544 R catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A complement(1281630..1282544) Escherichia coli str. K-12 substr. DH10B 6058524 YP_001730141.1 CDS emtA NC_010473.1 1282644 1283255 D lytic murein endotransglycosylase E 1282644..1283255 Escherichia coli str. K-12 substr. DH10B 6058529 YP_001730142.1 CDS ycgR NC_010473.1 1283257 1283991 R protein involved in flagellar function; hypothetical protein complement(1283257..1283991) Escherichia coli str. K-12 substr. DH10B 6058521 YP_001730143.1 CDS ymgE NC_010473.1 1284192 1284446 D inner membrane protein 1284192..1284446 Escherichia coli str. K-12 substr. DH10B 6058530 YP_001730144.1 CDS ycgY NC_010473.1 1284624 1285064 D hypothetical protein 1284624..1285064 Escherichia coli str. K-12 substr. DH10B 6058553 YP_001730145.1 CDS treA NC_010473.1 1285143 1286840 R periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase complement(1285143..1286840) Escherichia coli str. K-12 substr. DH10B 6058548 YP_001730146.1 CDS dhaM NC_010473.1 1287160 1288578 R phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL; dihydroxyacetone kinase subunit DhaM complement(1287160..1288578) Escherichia coli str. K-12 substr. DH10B 6058512 YP_001730147.1 CDS dhaL NC_010473.1 1288589 1289221 R with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; dihydroxyacetone kinase subunit DhaL complement(1288589..1289221) Escherichia coli str. K-12 substr. DH10B 6058517 YP_001730148.1 CDS dhaK NC_010473.1 1289232 1290302 R with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK complement(1289232..1290302) Escherichia coli str. K-12 substr. DH10B 6058509 YP_001730149.1 CDS dhaR NC_010473.1 1290530 1292449 D Positively regulates the dhaKLM operon from a sigma-70 promoter; DNA-binding transcriptional regulator DhaR 1290530..1292449 Escherichia coli str. K-12 substr. DH10B 6058511 YP_001730150.1 CDS ycgV NC_010473.1 1292549 1295416 R adhesin complement(1292549..1295416) Escherichia coli str. K-12 substr. DH10B 6058518 YP_001730151.1 CDS ychF NC_010473.1 1296185 1297276 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(1296185..1297276) Escherichia coli str. K-12 substr. DH10B 6058508 YP_001730152.1 CDS pth NC_010473.1 1297393 1297977 R Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase complement(1297393..1297977) Escherichia coli str. K-12 substr. DH10B 6058498 YP_001730153.1 CDS ychH NC_010473.1 1298255 1298533 D YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1298255..1298533 Escherichia coli str. K-12 substr. DH10B 6058502 YP_001730154.1 CDS ychM NC_010473.1 1298588 1300267 R putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; putative sulfate transporter YchM complement(1298588..1300267) Escherichia coli str. K-12 substr. DH10B 6058493 YP_001730155.1 CDS prsA NC_010473.1 1300392 1301339 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase complement(1300392..1301339) Escherichia coli str. K-12 substr. DH10B 6058488 YP_001730156.1 CDS ipk NC_010473.1 1301490 1302341 R An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(1301490..1302341) Escherichia coli str. K-12 substr. DH10B 6058489 YP_001730157.1 CDS lolB NC_010473.1 1302341 1302964 R Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB complement(1302341..1302964) Escherichia coli str. K-12 substr. DH10B 6058486 YP_001730158.1 CDS hemA NC_010473.1 1303178 1304434 D catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1303178..1304434 Escherichia coli str. K-12 substr. DH10B 6058490 YP_001730159.1 CDS prfA NC_010473.1 1304476 1305558 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1304476..1305558 Escherichia coli str. K-12 substr. DH10B 6058479 YP_001730160.1 CDS prmC NC_010473.1 1305558 1306391 D HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1305558..1306391 Escherichia coli str. K-12 substr. DH10B 6058480 YP_001730161.1 CDS ychQ NC_010473.1 1306388 1306780 D putative transcriptional regulator 1306388..1306780 Escherichia coli str. K-12 substr. DH10B 6058478 YP_001730162.1 CDS ychA NC_010473.1 1306784 1307593 D putative transcriptional regulator 1306784..1307593 Escherichia coli str. K-12 substr. DH10B 6058484 YP_001730163.1 CDS kdsA NC_010473.1 1307629 1308483 D catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1307629..1308483 Escherichia coli str. K-12 substr. DH10B 6058506 YP_001730164.1 CDS ldrA NC_010473.1 1308632 1308739 R toxic polypeptide, small complement(1308632..1308739) Escherichia coli str. K-12 substr. DH10B 6058496 YP_001730165.1 CDS ldrB NC_010473.1 1309167 1309274 R toxic polypeptide, small complement(1309167..1309274) Escherichia coli str. K-12 substr. DH10B 6062123 YP_001730166.1 CDS ldrC NC_010473.1 1309702 1309809 R toxic polypeptide, small complement(1309702..1309809) Escherichia coli str. K-12 substr. DH10B 6059541 YP_001730167.1 CDS chaA NC_010473.1 1310213 1311313 R calcium/sodium:proton antiporter complement(1310213..1311313) Escherichia coli str. K-12 substr. DH10B 6061868 YP_001730168.1 CDS chaB NC_010473.1 1311583 1311813 D in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 1311583..1311813 Escherichia coli str. K-12 substr. DH10B 6058469 YP_001730169.1 CDS chaC NC_010473.1 1311971 1312666 D regulatory protein for cation transport 1311971..1312666 Escherichia coli str. K-12 substr. DH10B 6058475 YP_001730170.1 CDS ychN NC_010473.1 1312710 1313063 R hypothetical protein complement(1312710..1313063) Escherichia coli str. K-12 substr. DH10B 6058467 YP_001730171.1 CDS ychO NC_010473.1 1313248 1314642 D hypothetical protein 1313248..1314642 Escherichia coli str. K-12 substr. DH10B 6058448 YP_001730172.1 CDS narL NC_010473.1 1314643 1315293 R two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL complement(1314643..1315293) Escherichia coli str. K-12 substr. DH10B 6058454 YP_001730173.1 CDS narX NC_010473.1 1315286 1317082 R nitrate/nitrite sensor protein NarX complement(1315286..1317082) Escherichia coli str. K-12 substr. DH10B 6058446 YP_001730174.1 CDS narK NC_010473.1 1317421 1318812 D nitrate/nitrite transporter 1317421..1318812 Escherichia coli str. K-12 substr. DH10B 6058441 YP_001730175.1 CDS narG NC_010473.1 1319328 1323071 D nitrate reductase 1 subunit alpha 1319328..1323071 Escherichia coli str. K-12 substr. DH10B 6058442 YP_001730176.1 CDS narH NC_010473.1 1323068 1324606 D nitrate reductase 1 subunit, beta (Fe-S) 1323068..1324606 Escherichia coli str. K-12 substr. DH10B 6058440 YP_001730177.1 CDS narJ NC_010473.1 1324603 1325313 D molybdenum-cofactor-assembly chaperone subunit (delta subunit) of nitrate reductase 1 1324603..1325313 Escherichia coli str. K-12 substr. DH10B 6058445 YP_001730178.1 CDS narI NC_010473.1 1325313 1325990 D nitrate reductase 1 subunit gamma (cytochrome b(NR)) 1325313..1325990 Escherichia coli str. K-12 substr. DH10B 6058432 YP_001730179.1 CDS ychS NC_010473.1 1326173 1326448 D hypothetical protein 1326173..1326448 Escherichia coli str. K-12 substr. DH10B 6058433 YP_001730180.1 CDS tpr NC_010473.1 1326551 1326640 R putative protamine-like protein complement(1326551..1326640) Escherichia coli str. K-12 substr. DH10B 6059178 YP_001730181.1 CDS purU NC_010473.1 1327246 1328088 R produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase complement(1327246..1328088) Escherichia coli str. K-12 substr. DH10B 6062204 YP_001730182.1 CDS ychJ NC_010473.1 1328138 1328596 R hypothetical protein complement(1328138..1328596) Escherichia coli str. K-12 substr. DH10B 6058458 YP_001730183.1 CDS rssA NC_010473.1 1328670 1329614 D hypothetical protein 1328670..1329614 Escherichia coli str. K-12 substr. DH10B 6058447 YP_001730184.1 CDS rssB NC_010473.1 1329706 1330719 D response regulator of RpoS 1329706..1330719 Escherichia coli str. K-12 substr. DH10B 6058424 YP_001730185.1 CDS galU NC_010473.1 1330921 1331829 D together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalU 1330921..1331829 Escherichia coli str. K-12 substr. DH10B 6058428 YP_001730186.1 CDS hns NC_010473.1 1331973 1332386 R global DNA-binding transcriptional dual regulator H-NS complement(1331973..1332386) Escherichia coli str. K-12 substr. DH10B 6058415 YP_001730187.1 CDS tdk NC_010473.1 1332991 1333608 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1332991..1333608 Escherichia coli str. K-12 substr. DH10B 6058419 YP_001730188.1 CDS adhE NC_010473.1 1334910 1337585 R bifunctional acetaldehyde-CoA/alcohol dehydrogenase complement(1334910..1337585) Escherichia coli str. K-12 substr. DH10B 6062148 YP_001730189.1 CDS ychE NC_010473.1 1338062 1338709 D hypothetical protein 1338062..1338709 Escherichia coli str. K-12 substr. DH10B 6058411 YP_001730190.1 CDS oppA NC_010473.1 1340224 1341855 D contains the nonsynonymous change N271Y; oligopeptide transporter periplasmic subunit 1340224..1341855 Escherichia coli str. K-12 substr. DH10B 6058404 YP_001730191.1 CDS oppB NC_010473.1 1341941 1342861 D oligopeptide transporter permease 1341941..1342861 Escherichia coli str. K-12 substr. DH10B 6058406 YP_001730192.1 CDS oppC NC_010473.1 1342876 1343784 D oligopeptide ABC transporter membrane protein 1342876..1343784 Escherichia coli str. K-12 substr. DH10B 6058402 YP_001730193.1 CDS oppD NC_010473.1 1343796 1344809 D oligopeptide ABC transporter ATP-binding protein 1343796..1344809 Escherichia coli str. K-12 substr. DH10B 6058393 YP_001730194.1 CDS oppF NC_010473.1 1344806 1345810 D contains the nonsynonymous change S325A; ATP-binding subunit of oligopeptide ABC transporter 1344806..1345810 Escherichia coli str. K-12 substr. DH10B 6058398 YP_001730195.1 CDS yciU NC_010473.1 1345863 1346192 R highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein complement(1345863..1346192) Escherichia coli str. K-12 substr. DH10B 6058392 YP_001730196.1 CDS cls NC_010473.1 1346227 1347687 R catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase complement(1346227..1347687) Escherichia coli str. K-12 substr. DH10B 6058400 YP_001730197.1 CDS kch NC_010473.1 1348058 1349311 R voltage-gated potassium channel complement(1348058..1349311) Escherichia coli str. K-12 substr. DH10B 6058380 YP_001730198.1 CDS int NC_010473.1 1349759 1351009 D integrase 1349759..1351009 Escherichia coli str. K-12 substr. DH10B 6058384 YP_001730199.1 CDS xis NC_010473.1 1351006 1351203 R excisionase complement(1351006..1351203) Escherichia coli str. K-12 substr. DH10B 6058375 YP_001730200.1 CDS ECDH10B_1315 NC_010473.1 1351245 1351490 R hypothetical protein complement(1351245..1351490) Escherichia coli str. K-12 substr. DH10B 6058389 YP_001730201.1 CDS ECDH10B_1317 NC_010473.1 1352518 1352952 R hypothetical protein complement(1352518..1352952) Escherichia coli str. K-12 substr. DH10B 6060027 YP_001730202.1 CDS exo NC_010473.1 1352943 1353623 R exonuclease complement(1352943..1353623) Escherichia coli str. K-12 substr. DH10B 6058403 YP_001730203.1 CDS bet NC_010473.1 1353620 1354537 R RecT protein complement(1353620..1354537) Escherichia coli str. K-12 substr. DH10B 6058369 YP_001730204.1 CDS ECDH10B_1320 NC_010473.1 1354547 1354828 R hypothetical protein complement(1354547..1354828) Escherichia coli str. K-12 substr. DH10B 6058371 YP_001730205.1 CDS ECDH10B_1321 NC_010473.1 1354836 1355804 R hypothetical protein complement(1354836..1355804) Escherichia coli str. K-12 substr. DH10B 6058367 YP_001730206.1 CDS ECDH10B_1322 NC_010473.1 1355909 1356799 R hypothetical protein complement(1355909..1356799) Escherichia coli str. K-12 substr. DH10B 6058368 YP_001730207.1 CDS kil NC_010473.1 1356756 1356965 R Rac prophage Kil protein; Kil overexpression leads to morphological defects and inhibits cell division; FtsZ inhibitor protein complement(1356756..1356965) Escherichia coli str. K-12 substr. DH10B 6058374 YP_001730208.1 CDS ECDH10B_1324 NC_010473.1 1356962 1357162 R hypothetical protein complement(1356962..1357162) Escherichia coli str. K-12 substr. DH10B 6058366 YP_001730209.1 CDS ECDH10B_1325 NC_010473.1 1357122 1357331 R hypothetical protein complement(1357122..1357331) Escherichia coli str. K-12 substr. DH10B 6058360 YP_001730210.1 CDS N NC_010473.1 1357487 1357783 R regulatory protein N complement(1357487..1357783) Escherichia coli str. K-12 substr. DH10B 6058361 YP_001730211.1 CDS 40 NC_010473.1 1358581 1359447 R protein 40A complement(1358581..1359447) Escherichia coli str. K-12 substr. DH10B 6058358 YP_001730212.1 CDS cI NC_010473.1 1359584 1360294 R repressor protein CI complement(1359584..1360294) Escherichia coli str. K-12 substr. DH10B 6058345 YP_001730213.1 CDS 30 NC_010473.1 1360412 1360633 D regulatory protein 30 (Cro) 1360412..1360633 Escherichia coli str. K-12 substr. DH10B 6058355 YP_001730214.1 CDS cII NC_010473.1 1360808 1361206 D regulatory protein CII 1360808..1361206 Escherichia coli str. K-12 substr. DH10B 6058344 YP_001730215.1 CDS ECDH10B_1331 NC_010473.1 1361292 1362200 D replication protein 15 (O) 1361292..1362200 Escherichia coli str. K-12 substr. DH10B 6058357 YP_001730216.1 CDS ECDH10B_1332 NC_010473.1 1362197 1362886 D replication protein 14 (P) 1362197..1362886 Escherichia coli str. K-12 substr. DH10B 6058341 YP_001730217.1 CDS ECDH10B_1333 NC_010473.1 1362950 1363669 D hypothetical protein 1362950..1363669 Escherichia coli str. K-12 substr. DH10B 6058342 YP_001730218.1 CDS ECDH10B_1334 NC_010473.1 1363842 1364345 D DLP12 prophage; hypothetical protein 1363842..1364345 Escherichia coli str. K-12 substr. DH10B 6058340 YP_001730219.1 CDS ECDH10B_1335 NC_010473.1 1364512 1365180 D serine/threonine-protein phosphatase 1364512..1365180 Escherichia coli str. K-12 substr. DH10B 6058343 YP_001730220.1 CDS rap NC_010473.1 1365173 1365814 D structure-specific endonuclease 1365173..1365814 Escherichia coli str. K-12 substr. DH10B 6058364 YP_001730221.1 CDS 17 NC_010473.1 1366130 1366939 D prophage antitermination protein 1366130..1366939 Escherichia coli str. K-12 substr. DH10B 6058359 YP_001730222.1 CDS 18 NC_010473.1 1367418 1367642 D lysis S family protein 1367418..1367642 Escherichia coli str. K-12 substr. DH10B 6058331 YP_001730223.1 CDS 19 NC_010473.1 1367620 1368114 D lysozyme-like protein 1367620..1368114 Escherichia coli str. K-12 substr. DH10B 6058333 YP_001730224.1 CDS Rz NC_010473.1 1368111 1368569 D Rz lysis protein 1368111..1368569 Escherichia coli str. K-12 substr. DH10B 6058325 YP_001730225.1 CDS Rz1 NC_010473.1 1368331 1368516 D putative lysis protein 1368331..1368516 Escherichia coli str. K-12 substr. DH10B 6058328 YP_001730226.1 CDS rha NC_010473.1 1368732 1369286 D Rha protein 1368732..1369286 Escherichia coli str. K-12 substr. DH10B 6058338 YP_001730227.1 CDS ECDH10B_1343 NC_010473.1 1369358 1369972 R hypothetical protein complement(1369358..1369972) Escherichia coli str. K-12 substr. DH10B 6058324 YP_001730228.1 CDS ECDH10B_1344 NC_010473.1 1369953 1370183 D putative Fur-regulated protein 1369953..1370183 Escherichia coli str. K-12 substr. DH10B 6058320 YP_001730229.1 CDS ECDH10B_1345 NC_010473.1 1370345 1371073 D putative Fur-regulated protein 1370345..1371073 Escherichia coli str. K-12 substr. DH10B 6058322 YP_001730230.1 CDS ECDH10B_1346 NC_010473.1 1371321 1371866 D phage DNA packaging protein Nu1 1371321..1371866 Escherichia coli str. K-12 substr. DH10B 6058308 YP_001730231.1 CDS 2 NC_010473.1 1371841 1373763 D DNA packaging protein 1371841..1373763 Escherichia coli str. K-12 substr. DH10B 6058305 YP_001730232.1 CDS W NC_010473.1 1373763 1373969 D head-to-tail joining protein 1373763..1373969 Escherichia coli str. K-12 substr. DH10B 6058306 YP_001730233.1 CDS B NC_010473.1 1373966 1375558 D head portal protein 1373966..1375558 Escherichia coli str. K-12 substr. DH10B 6058304 YP_001730234.1 CDS C NC_010473.1 1375539 1376882 D head protein 1375539..1376882 Escherichia coli str. K-12 substr. DH10B 6058307 YP_001730235.1 CDS D NC_010473.1 1376892 1377224 D head decoration protein; major capsid protein 1376892..1377224 Escherichia coli str. K-12 substr. DH10B 6058299 YP_001730236.1 CDS cynS NC_010473.1 1378249 1378719 D catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide; cyanate hydratase 1378249..1378719 Escherichia coli str. K-12 substr. DH10B 6061990 YP_001730237.1 CDS cynX NC_010473.1 1378752 1379906 D MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon; not essential; putative cyanate transporter 1378752..1379906 Escherichia coli str. K-12 substr. DH10B 6058298 YP_001730238.1 CDS lacA NC_010473.1 1380009 1380620 R transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown; galactoside O-acetyltransferase complement(1380009..1380620) Escherichia coli str. K-12 substr. DH10B 6058302 YP_001730239.1 CDS lacY NC_010473.1 1380686 1381939 R lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; galactoside permease complement(1380686..1381939) Escherichia coli str. K-12 substr. DH10B 6058323 YP_001730240.1 CDS lacI NC_010473.1 1385095 1386177 R transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor complement(1385095..1386177) Escherichia coli str. K-12 substr. DH10B 6058312 YP_001730241.1 CDS mhpR NC_010473.1 1386254 1387201 R activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional activator MhpR complement(1386254..1387201) Escherichia coli str. K-12 substr. DH10B 6058293 YP_001730242.1 CDS mhpA NC_010473.1 1387278 1388942 D catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate; 3-(3-hydroxyphenyl)propionate hydroxylase 1387278..1388942 Escherichia coli str. K-12 substr. DH10B 6058294 YP_001730243.1 CDS mhpB NC_010473.1 1388944 1389888 D catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family; 3-(2,3-dihydroxyphenyl)propionate dioxygenase 1388944..1389888 Escherichia coli str. K-12 substr. DH10B 6058289 YP_001730244.1 CDS mhpC NC_010473.1 1389891 1390772 D 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase 1389891..1390772 Escherichia coli str. K-12 substr. DH10B 6058291 YP_001730245.1 CDS tnpX NC_010473.1 1391119 1393215 R hypothetical protein complement(1391119..1393215) Escherichia coli str. K-12 substr. DH10B 6058296 YP_001730246.1 CDS tnpR NC_010473.1 1393231 1393782 R resolvase complement(1393231..1393782) Escherichia coli str. K-12 substr. DH10B 6059378 YP_001730247.1 CDS tnpA NC_010473.1 1393946 1396954 D transposase 1393946..1396954 Escherichia coli str. K-12 substr. DH10B 6058286 YP_001730248.1 CDS yciI NC_010473.1 1397989 1398285 R unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein complement(1397989..1398285) Escherichia coli str. K-12 substr. DH10B 6062101 YP_001730249.1 CDS tonB NC_010473.1 1398509 1399228 D membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transporter 1398509..1399228 Escherichia coli str. K-12 substr. DH10B 6058282 YP_001730250.1 CDS yciA NC_010473.1 1399268 1399666 R YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins; acyl-CoA thioester hydrolase complement(1399268..1399666) Escherichia coli str. K-12 substr. DH10B 6058277 YP_001730251.1 CDS yciB NC_010473.1 1399771 1400310 R Involved in cell division; probably involved in intracellular septation; intracellular septation protein A complement(1399771..1400310) Escherichia coli str. K-12 substr. DH10B 6058270 YP_001730252.1 CDS yciC NC_010473.1 1400340 1401083 R hypothetical protein complement(1400340..1401083) Escherichia coli str. K-12 substr. DH10B 6058273 YP_001730253.1 CDS ompW NC_010473.1 1401440 1402078 D receptor for colicin S4; outer membrane protein W 1401440..1402078 Escherichia coli str. K-12 substr. DH10B 6058269 YP_001730254.1 CDS yciE NC_010473.1 1402138 1402644 R hypothetical protein complement(1402138..1402644) Escherichia coli str. K-12 substr. DH10B 6058275 YP_001730255.1 CDS yciF NC_010473.1 1402690 1403190 R hypothetical protein complement(1402690..1403190) Escherichia coli str. K-12 substr. DH10B 6058259 YP_001730256.1 CDS yciG NC_010473.1 1403276 1403455 R hypothetical protein complement(1403276..1403455) Escherichia coli str. K-12 substr. DH10B 6058262 YP_001730257.1 CDS trpA NC_010473.1 1403836 1404642 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1403836..1404642) Escherichia coli str. K-12 substr. DH10B 6058258 YP_001730258.1 CDS trpB NC_010473.1 1404642 1405835 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1404642..1405835) Escherichia coli str. K-12 substr. DH10B 6058265 YP_001730259.1 CDS trpC NC_010473.1 1405847 1407205 R monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(1405847..1407205) Escherichia coli str. K-12 substr. DH10B 6058285 YP_001730260.1 CDS trpD NC_010473.1 1407209 1408804 R bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase complement(1407209..1408804) Escherichia coli str. K-12 substr. DH10B 6058280 YP_001730261.1 CDS trpE NC_010473.1 1408804 1410366 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1408804..1410366) Escherichia coli str. K-12 substr. DH10B 6058250 YP_001730263.1 CDS trpH NC_010473.1 1410640 1411521 D hypothetical protein 1410640..1411521 Escherichia coli str. K-12 substr. DH10B 6058247 YP_001730264.1 CDS yciO NC_010473.1 1411518 1412138 D hypothetical protein 1411518..1412138 Escherichia coli str. K-12 substr. DH10B 6058248 YP_001730265.1 CDS yciQ NC_010473.1 1412166 1414061 D inner membrane protein 1412166..1414061 Escherichia coli str. K-12 substr. DH10B 6058254 YP_001730266.1 CDS rluB NC_010473.1 1414272 1415147 D catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1414272..1415147 Escherichia coli str. K-12 substr. DH10B 6058246 YP_001730267.1 CDS btuR NC_010473.1 1415187 1415777 R catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase complement(1415187..1415777) Escherichia coli str. K-12 substr. DH10B 6058243 YP_001730268.1 CDS yciK NC_010473.1 1415774 1416532 R short chain dehydrogenase complement(1415774..1416532) Escherichia coli str. K-12 substr. DH10B 6058244 YP_001730269.1 CDS sohB NC_010473.1 1416752 1417801 D SohB; periplasmic protein; member of the peptidase S49 family; putative periplasmic protease 1416752..1417801 Escherichia coli str. K-12 substr. DH10B 6058240 YP_001730270.1 CDS yciN NC_010473.1 1417837 1418088 R hypothetical protein complement(1417837..1418088) Escherichia coli str. K-12 substr. DH10B 6058233 YP_001730271.1 CDS topA NC_010473.1 1418468 1421065 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1418468..1421065 Escherichia coli str. K-12 substr. DH10B 6058235 YP_001730272.1 CDS cysB NC_010473.1 1421275 1422249 D LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1421275..1422249 Escherichia coli str. K-12 substr. DH10B 6058232 YP_001730273.1 CDS ymiA NC_010473.1 1422580 1422708 D hypothetical protein 1422580..1422708 Escherichia coli str. K-12 substr. DH10B 6058238 YP_001730274.1 CDS yciX NC_010473.1 1422711 1422878 D hypothetical protein 1422711..1422878 Escherichia coli str. K-12 substr. DH10B 6058218 YP_001730275.1 CDS acnA NC_010473.1 1423251 1425926 D Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1423251..1425926 Escherichia coli str. K-12 substr. DH10B 6058220 YP_001730276.1 CDS ribA NC_010473.1 1425990 1426580 R catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II complement(1425990..1426580) Escherichia coli str. K-12 substr. DH10B 6058217 YP_001730277.1 CDS pgpB NC_010473.1 1426750 1427514 D phosphatidylglycerophosphatase B 1426750..1427514 Escherichia coli str. K-12 substr. DH10B 6058225 YP_001730278.1 CDS yciS NC_010473.1 1427663 1427971 D inner membrane protein 1427663..1427971 Escherichia coli str. K-12 substr. DH10B 6058245 YP_001730279.1 CDS yciM NC_010473.1 1427978 1429147 D tetratricopeptide repeat protein 1427978..1429147 Escherichia coli str. K-12 substr. DH10B 6058241 YP_001730280.1 CDS pyrF NC_010473.1 1429341 1430078 D type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1429341..1430078 Escherichia coli str. K-12 substr. DH10B 6058210 YP_001730281.1 CDS yciH NC_010473.1 1430078 1430404 D involved in start site selection during the initiation of translation; translation initiation factor Sui1 1430078..1430404 Escherichia coli str. K-12 substr. DH10B 6058214 YP_001730282.1 CDS osmB NC_010473.1 1430530 1430748 R lipoprotein complement(1430530..1430748) Escherichia coli str. K-12 substr. DH10B 6058208 YP_001730283.1 CDS yciT NC_010473.1 1431017 1431766 R DNA-binding transcriptional regulator complement(1431017..1431766) Escherichia coli str. K-12 substr. DH10B 6058209 YP_001730284.1 CDS gmr NC_010473.1 1432177 1434162 R c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator complement(1432177..1434162) Escherichia coli str. K-12 substr. DH10B 6058215 YP_001730285.1 CDS rnb NC_010473.1 1434398 1436332 R Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II complement(1434398..1436332) Escherichia coli str. K-12 substr. DH10B 6058207 YP_001730286.1 CDS yciW NC_010473.1 1436400 1437527 R oxidoreductase complement(1436400..1437527) Escherichia coli str. K-12 substr. DH10B 6058201 YP_001730287.1 CDS fabI NC_010473.1 1437671 1438459 R Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase complement(1437671..1438459) Escherichia coli str. K-12 substr. DH10B 6058204 YP_001730288.1 CDS ycjD NC_010473.1 1438827 1439180 R hypothetical protein complement(1438827..1439180) Escherichia coli str. K-12 substr. DH10B 6058198 YP_001730289.1 CDS sapF NC_010473.1 1439248 1440054 R antibiotic ABC transporter ATP-binding protein complement(1439248..1440054) Escherichia coli str. K-12 substr. DH10B 6058190 YP_001730290.1 CDS sapD NC_010473.1 1440056 1441048 R antibiotic ABC transporter ATP-binding protein complement(1440056..1441048) Escherichia coli str. K-12 substr. DH10B 6058196 YP_001730291.1 CDS sapC NC_010473.1 1441048 1441938 R antibiotic ABC transporter transmembrane protein complement(1441048..1441938) Escherichia coli str. K-12 substr. DH10B 6058187 YP_001730292.1 CDS sapB NC_010473.1 1441925 1442890 R antibiotic ABC transporter transmembrane protein complement(1441925..1442890) Escherichia coli str. K-12 substr. DH10B 6058197 YP_001730293.1 CDS sapA NC_010473.1 1442887 1444530 R antibiotic ABC transporter periplasmic-binding protein complement(1442887..1444530) Escherichia coli str. K-12 substr. DH10B 6058182 YP_001730294.1 CDS ymjA NC_010473.1 1444843 1445088 R hypothetical protein complement(1444843..1445088) Escherichia coli str. K-12 substr. DH10B 6058183 YP_001730295.1 CDS puuP NC_010473.1 1445222 1446607 R contains the nonsynonymous change Y110C; putrescine importer complement(1445222..1446607) Escherichia coli str. K-12 substr. DH10B 6058181 YP_001730296.1 CDS puuA NC_010473.1 1446910 1448328 R gamma-Glu-putrescine synthase complement(1446910..1448328) Escherichia coli str. K-12 substr. DH10B 6058184 YP_001730297.1 CDS puuD NC_010473.1 1448540 1449304 D catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate; gamma-glutamyl-gamma-aminobutyrate hydrolase 1448540..1449304 Escherichia coli str. K-12 substr. DH10B 6058206 YP_001730298.1 CDS puuR NC_010473.1 1449331 1449888 D regulates genes involved in putrescine degradation; DNA-binding transcriptional repressor PuuR 1449331..1449888 Escherichia coli str. K-12 substr. DH10B 6058199 YP_001730299.1 CDS puuC NC_010473.1 1450163 1451650 D catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation; gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase 1450163..1451650 Escherichia coli str. K-12 substr. DH10B 6058177 YP_001730300.1 CDS puuB NC_010473.1 1451652 1452932 D gamma-Glu-putrescine oxidase 1451652..1452932 Escherichia coli str. K-12 substr. DH10B 6058178 YP_001730301.1 CDS puuE NC_010473.1 1452970 1454235 D putrescine-inducible GABA aminotransferase; catalyzes the formation of glutamate and succinate semialdehyde from 4-aminobutyrate and 2-oxoglutarate; 4-aminobutyrate transaminase 1452970..1454235 Escherichia coli str. K-12 substr. DH10B 6058174 YP_001730302.1 CDS pspF NC_010473.1 1454355 1455332 R transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator complement(1454355..1455332) Escherichia coli str. K-12 substr. DH10B 6058175 YP_001730303.1 CDS pspA NC_010473.1 1455499 1456167 D involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1455499..1456167 Escherichia coli str. K-12 substr. DH10B 6058179 YP_001730304.1 CDS pspB NC_010473.1 1456221 1456445 D acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1456221..1456445 Escherichia coli str. K-12 substr. DH10B 6058173 YP_001730305.1 CDS pspC NC_010473.1 1456445 1456804 D with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1456445..1456804 Escherichia coli str. K-12 substr. DH10B 6058165 YP_001730306.1 CDS pspD NC_010473.1 1456813 1457034 D peripheral inner membrane phage-shock protein 1456813..1457034 Escherichia coli str. K-12 substr. DH10B 6058166 YP_001730307.1 CDS pspE NC_010473.1 1457109 1457423 D rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1457109..1457423 Escherichia coli str. K-12 substr. DH10B 6058162 YP_001730308.1 CDS ycjM NC_010473.1 1457636 1459315 D glucosyltransferase 1457636..1459315 Escherichia coli str. K-12 substr. DH10B 6058159 YP_001730309.1 CDS ycjN NC_010473.1 1459329 1460621 D sugar ABC transporter periplasmic-binding protein 1459329..1460621 Escherichia coli str. K-12 substr. DH10B 6058160 YP_001730310.1 CDS ycjO NC_010473.1 1460642 1461523 D sugar ABC transporter membrane protein 1460642..1461523 Escherichia coli str. K-12 substr. DH10B 6058158 YP_001730311.1 CDS ycjP NC_010473.1 1461510 1462352 D sugar ABC transporter membrane protein 1461510..1462352 Escherichia coli str. K-12 substr. DH10B 6058161 YP_001730312.1 CDS ycjQ NC_010473.1 1462383 1463435 D oxidoreductase, Zn-dependent and NAD(P)-binding 1462383..1463435 Escherichia coli str. K-12 substr. DH10B 6058151 YP_001730313.1 CDS ycjR NC_010473.1 1463454 1464242 D hypothetical protein 1463454..1464242 Escherichia coli str. K-12 substr. DH10B 6058155 YP_001730314.1 CDS ycjS NC_010473.1 1464252 1465307 D oxidoreductase, NADH-binding 1464252..1465307 Escherichia coli str. K-12 substr. DH10B 6058149 YP_001730315.1 CDS ycjT NC_010473.1 1465304 1467571 D hydrolase 1465304..1467571 Escherichia coli str. K-12 substr. DH10B 6058157 YP_001730316.1 CDS ycjU NC_010473.1 1467568 1468227 D beta-phosphoglucomutase 1467568..1468227 Escherichia coli str. K-12 substr. DH10B 6058168 YP_001730317.1 CDS ompG NC_010473.1 1469367 1470272 D outer membrane porin 1469367..1470272 Escherichia coli str. K-12 substr. DH10B 6062292 YP_001730318.1 CDS ycjW NC_010473.1 1470383 1471381 R DNA-binding transcriptional regulator complement(1470383..1471381) Escherichia coli str. K-12 substr. DH10B 6058144 YP_001730319.1 CDS ycjX NC_010473.1 1471537 1472934 D hypothetical protein 1471537..1472934 Escherichia coli str. K-12 substr. DH10B 6058147 YP_001730320.1 CDS ycjF NC_010473.1 1472931 1473992 D hypothetical protein 1472931..1473992 Escherichia coli str. K-12 substr. DH10B 6058141 YP_001730321.1 CDS tyrR NC_010473.1 1474140 1475681 D regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1474140..1475681 Escherichia coli str. K-12 substr. DH10B 6058143 YP_001730322.1 CDS tpx NC_010473.1 1475725 1476231 R antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase complement(1475725..1476231) Escherichia coli str. K-12 substr. DH10B 6058148 YP_001730323.1 CDS ycjG NC_010473.1 1476350 1477315 D L-Ala-D/L-Glu epimerase 1476350..1477315 Escherichia coli str. K-12 substr. DH10B 6060086 YP_001730324.1 CDS mpaA NC_010473.1 1477290 1478078 R murein peptide amidase A complement(1477290..1478078) Escherichia coli str. K-12 substr. DH10B 6058140 YP_001730325.1 CDS ymjC NC_010473.1 1478100 1478282 R oxidoreductase complement(1478100..1478282) Escherichia coli str. K-12 substr. DH10B 6058136 YP_001730326.1 CDS ycjY NC_010473.1 1478353 1479285 R hydrolase complement(1478353..1479285) Escherichia coli str. K-12 substr. DH10B 6058138 YP_001730327.1 CDS ycjZ NC_010473.1 1479411 1480310 D DNA-binding transcriptional regulator 1479411..1480310 Escherichia coli str. K-12 substr. DH10B 6058132 YP_001730328.1 CDS mppA NC_010473.1 1480647 1482260 D L-ala-gamma-D-glutamyl-meso-DAP ABC transporter periplasmic substrate-binding protein 1480647..1482260 Escherichia coli str. K-12 substr. DH10B 6058128 YP_001730329.1 CDS ynaI NC_010473.1 1482311 1483342 R inner membrane protein complement(1482311..1483342) Escherichia coli str. K-12 substr. DH10B 6058129 YP_001730330.1 CDS insH-4 NC_010473.1 1483496 1484512 D IS5 transposase and trans-activator 1483496..1484512 Escherichia coli str. K-12 substr. DH10B 6058127 YP_001730331.1 CDS ynaJ NC_010473.1 1484785 1485042 D inner membrane protein 1484785..1485042 Escherichia coli str. K-12 substr. DH10B 6058130 YP_001730332.1 CDS uspE NC_010473.1 1485092 1486042 R with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE complement(1485092..1486042) Escherichia coli str. K-12 substr. DH10B 6058118 YP_001730333.1 CDS fnr NC_010473.1 1486194 1486946 R Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator complement(1486194..1486946) Escherichia coli str. K-12 substr. DH10B 6058119 YP_001730334.1 CDS ogt NC_010473.1 1487141 1487656 R O-6-alkylguanine-DNA:cysteine-protein methyltransferase complement(1487141..1487656) Escherichia coli str. K-12 substr. DH10B 6058117 YP_001730335.1 CDS abgT NC_010473.1 1487667 1489193 R putative aminobenzoyl-glutamate transporter complement(1487667..1489193) Escherichia coli str. K-12 substr. DH10B 6058122 YP_001730336.1 CDS abgB NC_010473.1 1489230 1490675 R peptidase, aminobenzoyl-glutamate utilization protein complement(1489230..1490675) Escherichia coli str. K-12 substr. DH10B 6058139 YP_001730337.1 CDS abgA NC_010473.1 1490675 1491985 R peptidase, aminobenzoyl-glutamate utilization protein complement(1490675..1491985) Escherichia coli str. K-12 substr. DH10B 6058134 YP_001730338.1 CDS abgR NC_010473.1 1492161 1493069 D putative DNA-binding transcriptional regulator 1492161..1493069 Escherichia coli str. K-12 substr. DH10B 6058111 YP_001730339.1 CDS ydaL NC_010473.1 1493399 1493962 D hypothetical protein 1493399..1493962 Escherichia coli str. K-12 substr. DH10B 6062214 YP_001730340.1 CDS ydaM NC_010473.1 1493983 1495215 R diguanylate cyclase domain-containing signalling protein complement(1493983..1495215) Escherichia coli str. K-12 substr. DH10B 6058107 YP_001730341.1 CDS zntB NC_010473.1 1495470 1496453 D zinc transporter 1495470..1496453 Escherichia coli str. K-12 substr. DH10B 6058109 YP_001730342.1 CDS dbpA NC_010473.1 1496931 1498304 D exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1496931..1498304 Escherichia coli str. K-12 substr. DH10B 6058115 YP_001730343.1 CDS ttcA NC_010473.1 1498433 1499368 R TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase complement(1498433..1499368) Escherichia coli str. K-12 substr. DH10B 6058106 YP_001730344.1 CDS intR NC_010473.1 1499420 1500655 R contains a synonymous change in codon 113; Rac prophage integrase complement(1499420..1500655) Escherichia coli str. K-12 substr. DH10B 6058100 YP_001730345.1 CDS ydaQ NC_010473.1 1500657 1500872 R Rac prophage; protein complement(1500657..1500872) Escherichia coli str. K-12 substr. DH10B 6058103 YP_001730346.1 CDS ydaC NC_010473.1 1500951 1501160 R Rac prophage; hypothetical protein complement(1500951..1501160) Escherichia coli str. K-12 substr. DH10B 6058096 YP_001730347.1 CDS lar NC_010473.1 1501153 1501347 R seems to be involved in restriction alleviation and enhancement of modification by EcoKI, but not in restriction alleviation of type III restriction systems; Rac prophage; restriction alleviation and modification protein complement(1501153..1501347) Escherichia coli str. K-12 substr. DH10B 6058093 YP_001730348.1 CDS recT NC_010473.1 1501404 1502213 R recombination and repair protein RecT complement(1501404..1502213) Escherichia coli str. K-12 substr. DH10B 6058094 YP_001730349.1 CDS recE NC_010473.1 1502206 1504806 R The RecE (also known as exonuclease VIII) pathway is an alternative pathway for the initiation of homologous recombination in Escherichia coli. The RecE pathway is activated in recB, recC sbcA (suppressors of recB and recC) mutants. Activation of the RecE pathway results in the production of at least two phage proteins relevant for recombinational repair. RecE is a duplex DNA-specific exonuclease which produces 3' overhangs in duplex DNA by preferentially degrading the 5'-ending strands. Recombinational repair of E.coli chromosomal DNA involves as well other proteins: RecA, RecF, RecJ, RecO, RecR, and RuvC.; exonuclease VIII complement(1502206..1504806) Escherichia coli str. K-12 substr. DH10B 6058092 YP_001730350.1 CDS racC NC_010473.1 1504908 1505183 R Rac prophage hypothetical protein; hypothetical protein complement(1504908..1505183) Escherichia coli str. K-12 substr. DH10B 6058095 YP_001730351.1 CDS ydaE NC_010473.1 1505258 1505428 R Rac prophage; protein complement(1505258..1505428) Escherichia coli str. K-12 substr. DH10B 6058086 YP_001730352.1 CDS kil NC_010473.1 1505428 1505649 R Rac prophage Kil protein; Kil overexpression leads to morphological defects and inhibits cell division; FtsZ inhibitor protein complement(1505428..1505649) Escherichia coli str. K-12 substr. DH10B 6058087 YP_001730353.1 CDS sieB NC_010473.1 1506091 1506579 D Rac prophage; phage superinfection exclusion protein 1506091..1506579 Escherichia coli str. K-12 substr. DH10B 6058085 YP_001730354.1 CDS ydaF NC_010473.1 1506576 1506731 R Rac prophage; protein complement(1506576..1506731) Escherichia coli str. K-12 substr. DH10B 6058088 YP_001730355.1 CDS ydaG NC_010473.1 1506742 1506876 R Rac prophage; protein complement(1506742..1506876) Escherichia coli str. K-12 substr. DH10B 6058104 YP_001730356.1 CDS racR NC_010473.1 1507185 1507661 R Rac prophage; DNA-binding transcriptional regulator complement(1507185..1507661) Escherichia coli str. K-12 substr. DH10B 6058097 YP_001730357.1 CDS ydaS NC_010473.1 1507785 1508081 D Rac prophage; DNA-binding transcriptional regulator 1507785..1508081 Escherichia coli str. K-12 substr. DH10B 6058081 YP_001730358.1 CDS ydaT NC_010473.1 1508104 1508526 D Rac prophage; protein 1508104..1508526 Escherichia coli str. K-12 substr. DH10B 6058082 YP_001730359.1 CDS ydaU NC_010473.1 1508539 1509396 D Rac prophage; protein 1508539..1509396 Escherichia coli str. K-12 substr. DH10B 6058079 YP_001730360.1 CDS ydaV NC_010473.1 1509403 1510149 D putative replication protein 1509403..1510149 Escherichia coli str. K-12 substr. DH10B 6058080 YP_001730361.1 CDS ydaW NC_010473.1 1510172 1510732 D Rac prophage; DNA-binding protein 1510172..1510732 Escherichia coli str. K-12 substr. DH10B 6058083 YP_001730362.1 CDS rzpR NC_010473.1 1510765 1511064 D Rac prophage; defective peptidase 1510765..1511064 Escherichia coli str. K-12 substr. DH10B 6058078 YP_001730363.1 CDS rzoR NC_010473.1 1510820 1511005 D Rac prophage; lipoprotein 1510820..1511005 Escherichia coli str. K-12 substr. DH10B 6058365 YP_001730364.1 CDS trkG NC_010473.1 1511202 1512659 D Rac prophage; potassium transporter subunit 1511202..1512659 Escherichia coli str. K-12 substr. DH10B 6058076 YP_001730365.1 CDS ynaK NC_010473.1 1512797 1513060 D Rac prophage; protein 1512797..1513060 Escherichia coli str. K-12 substr. DH10B 6058101 YP_001730366.1 CDS ydaY NC_010473.1 1513041 1513400 D Rac prophage; protein 1513041..1513400 Escherichia coli str. K-12 substr. DH10B 6058531 YP_001730367.1 CDS ynaA NC_010473.1 1513874 1514902 D Rac prophage; tail protein 1513874..1514902 Escherichia coli str. K-12 substr. DH10B 6058452 YP_001730368.1 CDS insH-5 NC_010473.1 1515166 1516146 R contains the nonsynonymous change E214K; IS5 transposase and trans-activator complement(1515166..1516146) Escherichia coli str. K-12 substr. DH10B 6058629 YP_001730369.1 CDS stfR NC_010473.1 1516469 1519831 D Rac prophage; tail fiber protein 1516469..1519831 Escherichia coli str. K-12 substr. DH10B 6058450 YP_001730370.1 CDS tfaR NC_010473.1 1519831 1520406 D Rac prophage; tail fiber assembly protein 1519831..1520406 Escherichia coli str. K-12 substr. DH10B 6062420 YP_001730371.1 CDS pinR NC_010473.1 1520504 1521094 R Rac prophage; site-specific recombinase complement(1520504..1521094) Escherichia coli str. K-12 substr. DH10B 6062379 YP_001730372.1 CDS ynaE NC_010473.1 1521411 1521677 R Rac prophage; DNA-binding transcriptional regulator complement(1521411..1521677) Escherichia coli str. K-12 substr. DH10B 6062412 YP_001730373.1 CDS uspF NC_010473.1 1523804 1524238 R stress-induced protein, ATP-binding protein complement(1523804..1524238) Escherichia coli str. K-12 substr. DH10B 6062376 YP_001730374.1 CDS ompN NC_010473.1 1524379 1525512 R outer membrane pore protein N, non-specific complement(1524379..1525512) Escherichia coli str. K-12 substr. DH10B 6058077 YP_001730375.1 CDS ydbK NC_010473.1 1525879 1529403 R fused pyruvate-flavodoxin oxidoreductase: FeS binding protein complement(1525879..1529403) Escherichia coli str. K-12 substr. DH10B 6058837 YP_001730376.1 CDS ydbJ NC_010473.1 1529677 1529943 D hypothetical protein 1529677..1529943 Escherichia coli str. K-12 substr. DH10B 6062423 YP_001730377.1 CDS hslJ NC_010473.1 1529940 1530362 R heat-inducible protein complement(1529940..1530362) Escherichia coli str. K-12 substr. DH10B 6058772 YP_001730378.1 CDS ldhA NC_010473.1 1530473 1531462 R fermentative D-lactate dehydrogenase, NAD-dependent complement(1530473..1531462) Escherichia coli str. K-12 substr. DH10B 6062427 YP_001730379.1 CDS ydbH NC_010473.1 1531670 1534309 D hypothetical protein 1531670..1534309 Escherichia coli str. K-12 substr. DH10B 6059693 YP_001730380.1 CDS ynbE NC_010473.1 1534306 1534491 D lipoprotein 1534306..1534491 Escherichia coli str. K-12 substr. DH10B 6060452 YP_001730381.1 CDS ydbL NC_010473.1 1534499 1534825 D hypothetical protein 1534499..1534825 Escherichia coli str. K-12 substr. DH10B 6062369 YP_001730382.1 CDS feaR NC_010473.1 1534997 1535902 R activator of genes involved in phenylacetic acid catabolism; DNA-binding transcriptional activator FeaR complement(1534997..1535902) Escherichia coli str. K-12 substr. DH10B 6059416 YP_001730383.1 CDS feaB NC_010473.1 1536138 1537637 D phenylacetaldehyde dehydrogenase 1536138..1537637 Escherichia coli str. K-12 substr. DH10B 6059371 YP_001730384.1 CDS tynA NC_010473.1 1537695 1539968 R catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine; tyramine oxidase complement(1537695..1539968) Escherichia coli str. K-12 substr. DH10B 6059061 YP_001730385.1 CDS maoC NC_010473.1 1540216 1542261 R catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase complement(1540216..1542261) Escherichia coli str. K-12 substr. DH10B 6059814 YP_001730386.1 CDS paaA NC_010473.1 1542546 1543475 D with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; phenylacetate-CoA oxygenase subunit PaaA 1542546..1543475 Escherichia coli str. K-12 substr. DH10B 6059072 YP_001730387.1 CDS paaB NC_010473.1 1543487 1543774 D with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation; phenylacetate-CoA oxygenase subunit PaaB 1543487..1543774 Escherichia coli str. K-12 substr. DH10B 6062404 YP_001730388.1 CDS paaC NC_010473.1 1543783 1544529 D multicomponent oxygenase/reductase subunit for phenylacetic acid degradation 1543783..1544529 Escherichia coli str. K-12 substr. DH10B 6062418 YP_001730389.1 CDS paaD NC_010473.1 1544544 1545041 D multicomponent oxygenase/reductase subunit for phenylacetic acid degradation 1544544..1545041 Escherichia coli str. K-12 substr. DH10B 6062387 YP_001730390.1 CDS paaE NC_010473.1 1545049 1546119 D multicomponent oxygenase/reductase subunit for phenylacetic acid degradation 1545049..1546119 Escherichia coli str. K-12 substr. DH10B 6060395 YP_001730391.1 CDS paaF NC_010473.1 1546116 1546883 D enoyl-CoA hydratase-isomerase 1546116..1546883 Escherichia coli str. K-12 substr. DH10B 6060202 YP_001730392.1 CDS paaG NC_010473.1 1546883 1547671 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1546883..1547671 Escherichia coli str. K-12 substr. DH10B 6062430 YP_001730393.1 CDS paaH NC_010473.1 1547673 1549100 D converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; 3-hydroxyacyl-CoA dehydrogenase 1547673..1549100 Escherichia coli str. K-12 substr. DH10B 6062366 YP_001730394.1 CDS paaI NC_010473.1 1549090 1549512 D thioesterase 1549090..1549512 Escherichia coli str. K-12 substr. DH10B 6058888 YP_001730395.1 CDS paaJ NC_010473.1 1549512 1550717 D catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; beta-ketoadipyl CoA thiolase 1549512..1550717 Escherichia coli str. K-12 substr. DH10B 6058877 YP_001730396.1 CDS paaK NC_010473.1 1550744 1552057 D phenylacetyl-CoA ligase 1550744..1552057 Escherichia coli str. K-12 substr. DH10B 6059795 YP_001730397.1 CDS paaX NC_010473.1 1552158 1553108 D DNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive 1552158..1553108 Escherichia coli str. K-12 substr. DH10B 6058929 YP_001730398.1 CDS paaY NC_010473.1 1553090 1553680 D hexapeptide repeat-containing acetyltransferase 1553090..1553680 Escherichia coli str. K-12 substr. DH10B 6060171 YP_001730399.1 CDS insD-2 NC_010473.1 1556540 1557445 R IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD complement(1556540..1557445) Escherichia coli str. K-12 substr. DH10B 6058675 YP_001730400.1 CDS insC-2 NC_010473.1 1557403 1557813 R IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein complement(1557403..1557813) Escherichia coli str. K-12 substr. DH10B 6059743 YP_001730401.1 CDS insI-2 NC_010473.1 1557977 1559128 D contains two mutations: a synonymous change in codon 231, and the nonsynonymous change L261V; IS30 transposase 1557977..1559128 Escherichia coli str. K-12 substr. DH10B 6059182 YP_001730402.1 CDS ydbC NC_010473.1 1562840 1563700 D putative oxidoreductase 1562840..1563700 Escherichia coli str. K-12 substr. DH10B 6058634 YP_001730403.1 CDS ydbD NC_010473.1 1563763 1566069 D hypothetical protein 1563763..1566069 Escherichia coli str. K-12 substr. DH10B 6059602 YP_001730404.1 CDS ynbA NC_010473.1 1566240 1566845 D inner membrane protein 1566240..1566845 Escherichia coli str. K-12 substr. DH10B 6059604 YP_001730405.1 CDS ynbB NC_010473.1 1566845 1567741 D CDP-diglyceride synthase 1566845..1567741 Escherichia coli str. K-12 substr. DH10B 6058779 YP_001730406.1 CDS ynbC NC_010473.1 1567757 1569514 D hydrolase 1567757..1569514 Escherichia coli str. K-12 substr. DH10B 6060139 YP_001730407.1 CDS ynbD NC_010473.1 1569528 1570820 D phosphatase, inner membrane protein 1569528..1570820 Escherichia coli str. K-12 substr. DH10B 6062309 YP_001730408.1 CDS azoR NC_010473.1 1570874 1571479 R FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase complement(1570874..1571479) Escherichia coli str. K-12 substr. DH10B 6058519 YP_001730409.1 CDS hrpA NC_010473.1 1571680 1575582 D involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1571680..1575582 Escherichia coli str. K-12 substr. DH10B 6058664 YP_001730410.1 CDS ydcF NC_010473.1 1575854 1576654 D hypothetical protein 1575854..1576654 Escherichia coli str. K-12 substr. DH10B 6058176 YP_001730411.1 CDS aldA NC_010473.1 1576851 1578290 D NAD-linked; aldehyde dehydrogenase A 1576851..1578290 Escherichia coli str. K-12 substr. DH10B 6058212 YP_001730412.1 CDS cybB NC_010473.1 1579521 1580051 D B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1579521..1580051 Escherichia coli str. K-12 substr. DH10B 6058682 YP_001730413.1 CDS ydcA NC_010473.1 1580296 1580469 D hypothetical protein 1580296..1580469 Escherichia coli str. K-12 substr. DH10B 6060469 YP_001730414.1 CDS hokB NC_010473.1 1580541 1580690 R small toxic polypeptide complement(1580541..1580690) Escherichia coli str. K-12 substr. DH10B 6058870 YP_001730415.1 CDS mokB NC_010473.1 1580581 1580748 R regulatory peptide complement(1580581..1580748) Escherichia coli str. K-12 substr. DH10B 6062350 YP_001730416.1 CDS trg NC_010473.1 1581089 1582729 D methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor 1581089..1582729 Escherichia coli str. K-12 substr. DH10B 6061063 YP_001730417.1 CDS ydcI NC_010473.1 1582767 1583690 R DNA-binding transcriptional regulator complement(1582767..1583690) Escherichia coli str. K-12 substr. DH10B 6061383 YP_001730418.1 CDS ydcJ NC_010473.1 1583907 1585250 D hypothetical protein 1583907..1585250 Escherichia coli str. K-12 substr. DH10B 6062070 YP_001730419.1 CDS mdoD NC_010473.1 1585475 1587130 D involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1585475..1587130 Escherichia coli str. K-12 substr. DH10B 6060410 YP_001730420.1 CDS ydcH NC_010473.1 1587270 1587494 D hypothetical protein 1587270..1587494 Escherichia coli str. K-12 substr. DH10B 6058348 YP_001730421.1 CDS rimL NC_010473.1 1587557 1588096 D ribosomal-protein-L7/L12-serine acetyltransferase 1587557..1588096 Escherichia coli str. K-12 substr. DH10B 6059329 YP_001730422.1 CDS ydcK NC_010473.1 1588088 1589068 R hypothetical protein complement(1588088..1589068) Escherichia coli str. K-12 substr. DH10B 6061108 YP_001730423.1 CDS tehA NC_010473.1 1589192 1590184 D potassium-tellurite ethidium and proflavin transporter 1589192..1590184 Escherichia coli str. K-12 substr. DH10B 6062349 YP_001730424.1 CDS tehB NC_010473.1 1590181 1590774 D with TehA confers resistance to tellurite; tellurite resistance protein TehB 1590181..1590774 Escherichia coli str. K-12 substr. DH10B 6058278 YP_001730425.1 CDS ydcL NC_010473.1 1591076 1591744 D lipoprotein 1591076..1591744 Escherichia coli str. K-12 substr. DH10B 6058466 YP_001730426.1 CDS ydcM NC_010473.1 1592276 1593484 D transposase 1592276..1593484 Escherichia coli str. K-12 substr. DH10B 6058722 YP_001730427.1 CDS ydcO NC_010473.1 1593524 1594699 R benzoate transporter complement(1593524..1594699) Escherichia coli str. K-12 substr. DH10B 6060111 YP_001730428.1 CDS ydcN NC_010473.1 1594791 1595327 D DNA-binding transcriptional regulator 1594791..1595327 Escherichia coli str. K-12 substr. DH10B 6058252 YP_001730429.1 CDS ydcP NC_010473.1 1595400 1597361 D peptidase 1595400..1597361 Escherichia coli str. K-12 substr. DH10B 6058257 YP_001730430.1 CDS yncJ NC_010473.1 1597453 1597683 R hypothetical protein complement(1597453..1597683) Escherichia coli str. K-12 substr. DH10B 6058090 YP_001730431.1 CDS yncN NC_010473.1 1597905 1598081 D hypothetical protein 1597905..1598081 Escherichia coli str. K-12 substr. DH10B 6058354 YP_001730432.1 CDS ydcQ NC_010473.1 1598106 1598543 D DNA-binding transcriptional regulator 1598106..1598543 Escherichia coli str. K-12 substr. DH10B 6061141 YP_001730433.1 CDS ydcR NC_010473.1 1598622 1600028 D fused DNA-binding transcriptional regulator; amino transferase 1598622..1600028 Escherichia coli str. K-12 substr. DH10B 6058145 YP_001730434.1 CDS ydcS NC_010473.1 1600273 1601418 D spermidine/putrescine ABC transporter periplasmic-binding protein 1600273..1601418 Escherichia coli str. K-12 substr. DH10B 6058773 YP_001730435.1 CDS ydcT NC_010473.1 1601436 1602449 D spermidine/putrescine ABC transporter ATP-binding protein 1601436..1602449 Escherichia coli str. K-12 substr. DH10B 6058453 YP_001730436.1 CDS ydcU NC_010473.1 1602450 1603391 D spermidine/putrescine ABC transporter membrane protein 1602450..1603391 Escherichia coli str. K-12 substr. DH10B 6058387 YP_001730437.1 CDS ydcV NC_010473.1 1603381 1604175 D spermidine/putrescine ABC transporter membrane protein 1603381..1604175 Escherichia coli str. K-12 substr. DH10B 6058435 YP_001730438.1 CDS ydcW NC_010473.1 1604197 1605621 D catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1604197..1605621 Escherichia coli str. K-12 substr. DH10B 6059746 YP_001730439.1 CDS ydcX NC_010473.1 1606008 1606181 D inner membrane protein 1606008..1606181 Escherichia coli str. K-12 substr. DH10B 6062377 YP_001730440.1 CDS ydcY NC_010473.1 1606267 1606500 D hypothetical protein 1606267..1606500 Escherichia coli str. K-12 substr. DH10B 6058527 YP_001730441.1 CDS ydcZ NC_010473.1 1606501 1606950 R inner membrane protein complement(1606501..1606950) Escherichia coli str. K-12 substr. DH10B 6058284 YP_001730442.1 CDS yncA NC_010473.1 1606947 1607465 R acyltransferase complement(1606947..1607465) Escherichia coli str. K-12 substr. DH10B 6059479 YP_001730443.1 CDS yncB NC_010473.1 1607646 1608683 D oxidoreductase, Zn-dependent and NAD(P)-binding 1607646..1608683 Escherichia coli str. K-12 substr. DH10B 6062331 YP_001730444.1 CDS yncC NC_010473.1 1608881 1609546 D putative DNA-binding transcriptional regulator 1608881..1609546 Escherichia coli str. K-12 substr. DH10B 6062347 YP_001730445.1 CDS yncD NC_010473.1 1609582 1611684 R iron outer membrane transporter complement(1609582..1611684) Escherichia coli str. K-12 substr. DH10B 6062253 YP_001730446.1 CDS yncE NC_010473.1 1611926 1612987 D hypothetical protein 1611926..1612987 Escherichia coli str. K-12 substr. DH10B 6062405 YP_001730447.1 CDS ansP NC_010473.1 1613100 1614599 R L-asparagine transporter complement(1613100..1614599) Escherichia coli str. K-12 substr. DH10B 6062132 YP_001730448.1 CDS yncG NC_010473.1 1614866 1615483 D hypothetical protein 1614866..1615483 Escherichia coli str. K-12 substr. DH10B 6058133 YP_001730449.1 CDS yncH NC_010473.1 1615559 1615771 D hypothetical protein 1615559..1615771 Escherichia coli str. K-12 substr. DH10B 6058434 YP_001730450.1 CDS ydcD NC_010473.1 1618541 1619023 D hypothetical protein 1618541..1619023 Escherichia coli str. K-12 substr. DH10B 6058732 YP_001730451.1 CDS ydcC NC_010473.1 1620435 1621571 D hypothetical protein 1620435..1621571 Escherichia coli str. K-12 substr. DH10B 6058797 YP_001730452.1 CDS pptA NC_010473.1 1621671 1621904 D 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 1621671..1621904 Escherichia coli str. K-12 substr. DH10B 6060737 YP_001730453.1 CDS yddH NC_010473.1 1621901 1622470 R hypothetical protein complement(1621901..1622470) Escherichia coli str. K-12 substr. DH10B 6060426 YP_001730454.1 CDS nhoA NC_010473.1 1622643 1623488 D N-hydroxyarylamine O-acetyltransferase 1622643..1623488 Escherichia coli str. K-12 substr. DH10B 6058438 YP_001730455.1 CDS yddE NC_010473.1 1623584 1624477 R hypothetical protein complement(1623584..1624477) Escherichia coli str. K-12 substr. DH10B 6058221 YP_001730456.1 CDS narV NC_010473.1 1624556 1625236 R nitrate reductase 2 (NRZ), gamma subunit complement(1624556..1625236) Escherichia coli str. K-12 substr. DH10B 6058597 YP_001730457.1 CDS narW NC_010473.1 1625233 1625928 R nitrate reductase 2 (NRZ), delta subunit (assembly subunit) complement(1625233..1625928) Escherichia coli str. K-12 substr. DH10B 6058474 YP_001730458.1 CDS narY NC_010473.1 1625928 1627472 R nitrate reductase 2 (NRZ), beta subunit complement(1625928..1627472) Escherichia coli str. K-12 substr. DH10B 6058317 YP_001730459.1 CDS narZ NC_010473.1 1627469 1631209 R nitrate reductase 2 (NRZ), alpha subunit complement(1627469..1631209) Escherichia coli str. K-12 substr. DH10B 6058229 YP_001730460.1 CDS narU NC_010473.1 1631291 1632679 R nitrate/nitrite transporter complement(1631291..1632679) Escherichia coli str. K-12 substr. DH10B 6062264 YP_001730461.1 CDS yddJ NC_010473.1 1633003 1633338 R hypothetical protein complement(1633003..1633338) Escherichia coli str. K-12 substr. DH10B 6058596 YP_001730462.1 CDS yddK NC_010473.1 1633377 1634333 R hypothetical protein complement(1633377..1634333) Escherichia coli str. K-12 substr. DH10B 6062304 YP_001730463.1 CDS yddL NC_010473.1 1634357 1634647 R lipoprotein complement(1634357..1634647) Escherichia coli str. K-12 substr. DH10B 6062209 YP_001730464.1 CDS yddG NC_010473.1 1634907 1635788 R hypothetical protein complement(1634907..1635788) Escherichia coli str. K-12 substr. DH10B 6062375 YP_001730465.1 CDS fdnG NC_010473.1 1636020 1639067 D formate dehydrogenase-N subunit alpha, nitrate-inducible 1636020..1639067 Escherichia coli str. K-12 substr. DH10B 6062270 YP_001730466.1 CDS fdnH NC_010473.1 1639080 1639964 D formate dehydrogenase-N, Fe-S (beta) subunit, nitrate-inducible 1639080..1639964 Escherichia coli str. K-12 substr. DH10B 6062344 YP_001730467.1 CDS fdnI NC_010473.1 1639957 1640610 D nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1639957..1640610 Escherichia coli str. K-12 substr. DH10B 6062240 YP_001730468.1 CDS yddM NC_010473.1 1641017 1641301 R DNA-binding transcriptional regulator complement(1641017..1641301) Escherichia coli str. K-12 substr. DH10B 6062275 YP_001730469.1 CDS adhP NC_010473.1 1641447 1642457 R similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase complement(1641447..1642457) Escherichia coli str. K-12 substr. DH10B 6062183 YP_001730470.1 CDS maeA NC_010473.1 1642591 1644288 R malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase complement(1642591..1644288) Escherichia coli str. K-12 substr. DH10B 6062279 YP_001730471.1 CDS rpsV NC_010473.1 1644445 1644582 R protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase; 30S ribosomal subunit S22 complement(1644445..1644582) Escherichia coli str. K-12 substr. DH10B 6058222 YP_001730472.1 CDS bdm NC_010473.1 1644684 1644899 R biofilm-dependent modulation protein complement(1644684..1644899) Escherichia coli str. K-12 substr. DH10B 6062340 YP_001730473.1 CDS osmC NC_010473.1 1645244 1645675 D osmotically inducible, stress-inducible membrane protein 1645244..1645675 Escherichia coli str. K-12 substr. DH10B 6062028 YP_001730474.1 CDS ddpF NC_010473.1 1645731 1646657 R D-alanine-D-alanine ABC transporter ATP-binding protein complement(1645731..1646657) Escherichia coli str. K-12 substr. DH10B 6062114 YP_001730475.1 CDS ddpD NC_010473.1 1646650 1647636 R D-alanine-D-alanine ABC transporter ATP-binding protein complement(1646650..1647636) Escherichia coli str. K-12 substr. DH10B 6061939 YP_001730476.1 CDS ddpC NC_010473.1 1647633 1648529 R ATP-dependent peptide transporter membrane subunit complement(1647633..1648529) Escherichia coli str. K-12 substr. DH10B 6062020 YP_001730477.1 CDS ddpB NC_010473.1 1648526 1649548 R D-alanine-D-alanine ABC transporter membrane protein complement(1648526..1649548) Escherichia coli str. K-12 substr. DH10B 6062174 YP_001730478.1 CDS ddpA NC_010473.1 1649550 1651100 R D-alanine-D-alanine ABC transporter periplasmic-binding protein complement(1649550..1651100) Escherichia coli str. K-12 substr. DH10B 6061876 YP_001730479.1 CDS ddpX NC_010473.1 1651114 1651695 R catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis; D-alanyl-D-alanine dipeptidase complement(1651114..1651695) Escherichia coli str. K-12 substr. DH10B 6061631 YP_001730480.1 CDS dos NC_010473.1 1651953 1654352 R heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate; cAMP phosphodiesterase complement(1651953..1654352) Escherichia coli str. K-12 substr. DH10B 6061724 YP_001730481.1 CDS yddV NC_010473.1 1654377 1655759 R diguanylate cyclase complement(1654377..1655759) Escherichia coli str. K-12 substr. DH10B 6061329 YP_001730482.1 CDS yddW NC_010473.1 1656123 1657442 R liprotein complement(1656123..1657442) Escherichia coli str. K-12 substr. DH10B 6060513 YP_001730483.1 CDS gadC NC_010473.1 1657573 1659108 R glutamate:gamma-aminobutyric acid antiporter complement(1657573..1659108) Escherichia coli str. K-12 substr. DH10B 6060508 YP_001730484.1 CDS gadB NC_010473.1 1659264 1660664 R glutamate decarboxylase complement(1659264..1660664) Escherichia coli str. K-12 substr. DH10B 6062180 YP_001730485.1 CDS pqqL NC_010473.1 1661026 1663821 R peptidase complement(1661026..1663821) Escherichia coli str. K-12 substr. DH10B 6061220 YP_001730486.1 CDS yddB NC_010473.1 1663866 1666238 R porin protein complement(1663866..1666238) Escherichia coli str. K-12 substr. DH10B 6062107 YP_001730487.1 CDS yddA NC_010473.1 1666276 1667961 R multidrug ABC transporter membrane protein; ATP-binding protein complement(1666276..1667961) Escherichia coli str. K-12 substr. DH10B 6062186 YP_001730488.1 CDS ydeM NC_010473.1 1668252 1669409 R hypothetical protein complement(1668252..1669409) Escherichia coli str. K-12 substr. DH10B 6062422 YP_001730489.1 CDS ydeN NC_010473.1 1669461 1671143 R hypothetical protein complement(1669461..1671143) Escherichia coli str. K-12 substr. DH10B 6061053 YP_001730490.1 CDS ydeO NC_010473.1 1671545 1672306 R regulates the cellular response to acid resistance; transcriptional regulator YdeO complement(1671545..1672306) Escherichia coli str. K-12 substr. DH10B 6061835 YP_001730491.1 CDS ydeP NC_010473.1 1672826 1675105 R in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family; putative oxidoreductase complement(1672826..1675105) Escherichia coli str. K-12 substr. DH10B 6061567 YP_001730492.1 CDS ydeQ NC_010473.1 1675439 1676353 R fimbrial-like adhesin protein complement(1675439..1676353) Escherichia coli str. K-12 substr. DH10B 6062118 YP_001730493.1 CDS ydeR NC_010473.1 1676412 1676915 R fimbrial-like adhesin protein complement(1676412..1676915) Escherichia coli str. K-12 substr. DH10B 6062116 YP_001730494.1 CDS yneL NC_010473.1 1678006 1678185 R transcriptional regulator complement(1678006..1678185) Escherichia coli str. K-12 substr. DH10B 6062201 YP_001730495.1 CDS hipA NC_010473.1 1678503 1679825 R regulator with hipB complement(1678503..1679825) Escherichia coli str. K-12 substr. DH10B 6062163 YP_001730496.1 CDS hipB NC_010473.1 1679825 1680091 R DNA-binding transcriptional regulator HipB complement(1679825..1680091) Escherichia coli str. K-12 substr. DH10B 6061012 YP_001730497.1 CDS ydeU NC_010473.1 1680314 1681714 R hypothetical protein complement(1680314..1681714) Escherichia coli str. K-12 substr. DH10B 6062203 YP_001730498.1 CDS ydeK NC_010473.1 1681758 1685735 R putative lipoprotein complement(1681758..1685735) Escherichia coli str. K-12 substr. DH10B 6062172 YP_001730499.1 CDS lsrK NC_010473.1 1686266 1687858 R autoinducer-2 (AI-2) kinase complement(1686266..1687858) Escherichia coli str. K-12 substr. DH10B 6060598 YP_001730500.1 CDS lsrR NC_010473.1 1687937 1688890 R lsr operon transcriptional repressor complement(1687937..1688890) Escherichia coli str. K-12 substr. DH10B 6062136 YP_001730501.1 CDS lsrA NC_010473.1 1689139 1690674 D AI2 ABC transporter ATP-binding protein 1689139..1690674 Escherichia coli str. K-12 substr. DH10B 6061189 YP_001730502.1 CDS lsrC NC_010473.1 1690668 1691696 D AI2 ABC transporter membrane protein 1690668..1691696 Escherichia coli str. K-12 substr. DH10B 6062077 YP_001730503.1 CDS lsrD NC_010473.1 1691696 1692688 D AI2 ABC transporter membrane protein 1691696..1692688 Escherichia coli str. K-12 substr. DH10B 6061146 YP_001730504.1 CDS lsrB NC_010473.1 1692700 1693722 D AI2 ABC transporter periplasmic-binding protein 1692700..1693722 Escherichia coli str. K-12 substr. DH10B 6061184 YP_001730505.1 CDS lsrF NC_010473.1 1693749 1694624 D aldolase 1693749..1694624 Escherichia coli str. K-12 substr. DH10B 6062049 YP_001730506.1 CDS lsrG NC_010473.1 1694648 1694938 D autoinducer-2 (AI-2) modifying protein LsrG 1694648..1694938 Escherichia coli str. K-12 substr. DH10B 6062083 YP_001730507.1 CDS tam NC_010473.1 1694995 1695753 D catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 1694995..1695753 Escherichia coli str. K-12 substr. DH10B 6061200 YP_001730508.1 CDS yneE NC_010473.1 1695757 1696671 R inner membrane protein complement(1695757..1696671) Escherichia coli str. K-12 substr. DH10B 6061192 YP_001730509.1 CDS yneF NC_010473.1 1698556 1699503 R diguanylate cyclase complement(1698556..1699503) Escherichia coli str. K-12 substr. DH10B 6062131 YP_001730510.1 CDS yneG NC_010473.1 1699615 1699974 R hypothetical protein complement(1699615..1699974) Escherichia coli str. K-12 substr. DH10B 6062173 YP_001730511.1 CDS yneH NC_010473.1 1699974 1700900 R catalyzes the formation of glutamate from glutamine; glutaminase complement(1699974..1700900) Escherichia coli str. K-12 substr. DH10B 6062225 YP_001730512.1 CDS yneI NC_010473.1 1700964 1702352 R in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; putative succinate-semialdehyde dehydrogenase complement(1700964..1702352) Escherichia coli str. K-12 substr. DH10B 6061065 YP_001730513.1 CDS yneJ NC_010473.1 1702453 1703334 D DNA-binding transcriptional regulator 1702453..1703334 Escherichia coli str. K-12 substr. DH10B 6061208 YP_001730514.1 CDS yneK NC_010473.1 1703412 1704527 D hypothetical protein 1703412..1704527 Escherichia coli str. K-12 substr. DH10B 6062227 YP_001730515.1 CDS ydeA NC_010473.1 1704677 1705867 D sugar efflux transporter 1704677..1705867 Escherichia coli str. K-12 substr. DH10B 6061118 YP_001730516.1 CDS marC NC_010473.1 1705892 1706557 R protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC complement(1705892..1706557) Escherichia coli str. K-12 substr. DH10B 6060681 YP_001730517.1 CDS marR NC_010473.1 1706769 1707203 D Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 1706769..1707203 Escherichia coli str. K-12 substr. DH10B 6061210 YP_001730518.1 CDS marA NC_010473.1 1707223 1707606 D transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 1707223..1707606 Escherichia coli str. K-12 substr. DH10B 6060688 YP_001730519.1 CDS marB NC_010473.1 1707638 1707856 D hypothetical protein 1707638..1707856 Escherichia coli str. K-12 substr. DH10B 6062207 YP_001730520.1 CDS eamA NC_010473.1 1707887 1708786 R O-acetylserine/cysteine export protein complement(1707887..1708786) Escherichia coli str. K-12 substr. DH10B 6061227 YP_001730521.1 CDS ydeE NC_010473.1 1708981 1710168 D YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; putative MFS-type transporter YdeE 1708981..1710168 Escherichia coli str. K-12 substr. DH10B 6061181 YP_001730522.1 CDS ydeH NC_010473.1 1710609 1711499 R hypothetical protein complement(1710609..1711499) Escherichia coli str. K-12 substr. DH10B 6061187 YP_001730523.1 CDS ydeI NC_010473.1 1711754 1712146 R hypothetical protein complement(1711754..1712146) Escherichia coli str. K-12 substr. DH10B 6062243 YP_001730524.1 CDS ydeJ NC_010473.1 1712422 1712940 D competence damage-inducible protein A 1712422..1712940 Escherichia coli str. K-12 substr. DH10B 6061253 YP_001730525.1 CDS dcp NC_010473.1 1712984 1715029 R dipeptidyl carboxypeptidase II complement(1712984..1715029) Escherichia coli str. K-12 substr. DH10B 6062221 YP_001730526.1 CDS ydfG NC_010473.1 1715166 1715912 D NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 1715166..1715912 Escherichia coli str. K-12 substr. DH10B 6061259 YP_001730527.1 CDS ydfH NC_010473.1 1716001 1716687 D DNA-binding transcriptional regulator 1716001..1716687 Escherichia coli str. K-12 substr. DH10B 6061244 YP_001730528.1 CDS ydfZ NC_010473.1 1716864 1717067 D hypothetical protein 1716864..1717067 Escherichia coli str. K-12 substr. DH10B 6060682 YP_001730529.1 CDS ydfI NC_010473.1 1717102 1718562 R mannonate dehydrogenase complement(1717102..1718562) Escherichia coli str. K-12 substr. DH10B 6061033 YP_001730530.1 CDS ydfJ NC_010473.1 1718651 1719934 R transporter complement(1718651..1719934) Escherichia coli str. K-12 substr. DH10B 6060704 YP_001730531.1 CDS ydfK NC_010473.1 1720688 1720954 D Qin prophage; DNA-binding transcriptional regulator 1720688..1720954 Escherichia coli str. K-12 substr. DH10B 6061268 YP_001730532.1 CDS pinQ NC_010473.1 1721271 1721861 D Qin prophage; site-specific recombinase 1721271..1721861 Escherichia coli str. K-12 substr. DH10B 6061272 YP_001730533.1 CDS tfaQ NC_010473.1 1721959 1722534 R Qin prophage; tail fiber assembly protein complement(1721959..1722534) Escherichia coli str. K-12 substr. DH10B 6060709 YP_001730534.1 CDS stfQ NC_010473.1 1722534 1723496 R Qin prophage; side tail fiber assembly protein complement(1722534..1723496) Escherichia coli str. K-12 substr. DH10B 6061214 YP_001730535.1 CDS nohA NC_010473.1 1723447 1724016 R Qin prophage; packaging protein complement(1723447..1724016) Escherichia coli str. K-12 substr. DH10B 6061234 YP_001730536.1 CDS ynfO NC_010473.1 1724405 1724638 D Qin prophage; protein 1724405..1724638 Escherichia coli str. K-12 substr. DH10B 6060716 YP_001730537.1 CDS ydfO NC_010473.1 1724696 1725106 D Qin prophage; protein 1724696..1725106 Escherichia coli str. K-12 substr. DH10B 6061247 YP_001730538.1 CDS gnsB NC_010473.1 1725258 1725431 R Qin prophage; protein complement(1725258..1725431) Escherichia coli str. K-12 substr. DH10B 6061310 YP_001730539.1 CDS ynfN NC_010473.1 1725603 1725758 R Qin prophage; protein complement(1725603..1725758) Escherichia coli str. K-12 substr. DH10B 6060722 YP_001730540.1 CDS cspI NC_010473.1 1726104 1726316 R Qin prophage; cold shock protein complement(1726104..1726316) Escherichia coli str. K-12 substr. DH10B 6062212 YP_001730541.1 CDS ydfP NC_010473.1 1726679 1727176 R Qin prophage; protein complement(1726679..1727176) Escherichia coli str. K-12 substr. DH10B 6060725 YP_001730542.1 CDS ydfQ NC_010473.1 1727173 1727706 R Qin prophage; lysozyme complement(1727173..1727706) Escherichia coli str. K-12 substr. DH10B 6061318 YP_001730543.1 CDS ydfR NC_010473.1 1727703 1728014 R Qin prophage; protein complement(1727703..1728014) Escherichia coli str. K-12 substr. DH10B 6061345 YP_001730544.1 CDS essQ NC_010473.1 1728019 1728234 R Qin prophage; S lysis protein complement(1728019..1728234) Escherichia coli str. K-12 substr. DH10B 6062246 YP_001730545.1 CDS cspB NC_010473.1 1728988 1729203 R Qin prophage; cold shock protein complement(1728988..1729203) Escherichia coli str. K-12 substr. DH10B 6061348 YP_001730546.1 CDS cspF NC_010473.1 1729504 1729716 D Qin prophage; cold shock protein 1729504..1729716 Escherichia coli str. K-12 substr. DH10B 6062283 YP_001730547.1 CDS ydfT NC_010473.1 1730138 1730890 R Qin prophage; antitermination protein Q complement(1730138..1730890) Escherichia coli str. K-12 substr. DH10B 6060566 YP_001730548.1 CDS rem NC_010473.1 1732300 1732551 R Qin prophage; protein complement(1732300..1732551) Escherichia coli str. K-12 substr. DH10B 6061292 YP_001730549.1 CDS hokD NC_010473.1 1732768 1732923 R Qin prophage; small toxic polypeptide complement(1732768..1732923) Escherichia coli str. K-12 substr. DH10B 6061309 YP_001730550.1 CDS relE NC_010473.1 1732995 1733282 R Qin prophage; toxin of the RelE-RelB toxin-antitoxin system complement(1732995..1733282) Escherichia coli str. K-12 substr. DH10B 6062222 YP_001730551.1 CDS relB NC_010473.1 1733282 1733521 R Qin prophage; bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor; bifunctional antitoxin/transcriptional repressor RelB complement(1733282..1733521) Escherichia coli str. K-12 substr. DH10B 6059869 YP_001730552.1 CDS ydfV NC_010473.1 1733546 1733851 D Qin prophage; protein 1733546..1733851 Escherichia coli str. K-12 substr. DH10B 6062351 YP_001730553.1 CDS flxA NC_010473.1 1734054 1734386 D Qin prophage; protein 1734054..1734386 Escherichia coli str. K-12 substr. DH10B 6059345 YP_001730554.1 CDS ydfW NC_010473.1 1734823 1734972 R Qin prophage; protein complement(1734823..1734972) Escherichia coli str. K-12 substr. DH10B 6061354 YP_001730555.1 CDS ydfX NC_010473.1 1734995 1735285 R Qin prophage; protein complement(1734995..1735285) Escherichia coli str. K-12 substr. DH10B 6062373 YP_001730556.1 CDS dicC NC_010473.1 1735269 1735499 R DNA-binding transcriptional regulator DicC complement(1735269..1735499) Escherichia coli str. K-12 substr. DH10B 6062401 YP_001730557.1 CDS dicA NC_010473.1 1735583 1735990 D The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown.; transcriptional repressor DicA 1735583..1735990 Escherichia coli str. K-12 substr. DH10B 6062402 YP_001730558.1 CDS ydfA NC_010473.1 1736157 1736312 D Qin prophage; protein 1736157..1736312 Escherichia coli str. K-12 substr. DH10B 6062378 YP_001730559.1 CDS ydfB NC_010473.1 1736314 1736442 D Qin prophage; protein 1736314..1736442 Escherichia coli str. K-12 substr. DH10B 6062358 YP_001730560.1 CDS ydfC NC_010473.1 1736472 1736690 D Qin prophage; protein 1736472..1736690 Escherichia coli str. K-12 substr. DH10B 6062355 YP_001730561.1 CDS dicB NC_010473.1 1737258 1737446 D Qin prophage; cell division inhibition protein 1737258..1737446 Escherichia coli str. K-12 substr. DH10B 6060569 YP_001730562.1 CDS ydfD NC_010473.1 1737443 1737634 D Qin prophage; protein 1737443..1737634 Escherichia coli str. K-12 substr. DH10B 6062363 YP_001730563.1 CDS ydfE NC_010473.1 1737727 1738647 D Qin prophage; protein 1737727..1738647 Escherichia coli str. K-12 substr. DH10B 6062330 YP_001730564.1 CDS rspB NC_010473.1 1741881 1742900 R putative dehydrogenase complement(1741881..1742900) Escherichia coli str. K-12 substr. DH10B 6062320 YP_001730565.1 CDS rspA NC_010473.1 1742912 1744126 R dehydratase complement(1742912..1744126) Escherichia coli str. K-12 substr. DH10B 6062360 YP_001730566.1 CDS ynfA NC_010473.1 1744332 1744658 R hypothetical protein complement(1744332..1744658) Escherichia coli str. K-12 substr. DH10B 6062223 YP_001730567.1 CDS ynfB NC_010473.1 1744793 1745134 D hypothetical protein 1744793..1745134 Escherichia coli str. K-12 substr. DH10B 6062371 YP_001730568.1 CDS speG NC_010473.1 1745169 1745729 D spermidine N1-acetyltransferase 1745169..1745729 Escherichia coli str. K-12 substr. DH10B 6062365 YP_001730569.1 CDS ynfC NC_010473.1 1745732 1746442 R hypothetical protein complement(1745732..1746442) Escherichia coli str. K-12 substr. DH10B 6062381 YP_001730570.1 CDS ynfD NC_010473.1 1746550 1746855 D hypothetical protein 1746550..1746855 Escherichia coli str. K-12 substr. DH10B 6062303 YP_001730571.1 CDS ynfE NC_010473.1 1747054 1749480 D oxidoreductase subunit 1747054..1749480 Escherichia coli str. K-12 substr. DH10B 6062296 YP_001730572.1 CDS ynfF NC_010473.1 1749541 1751964 D oxidoreductase subunit 1749541..1751964 Escherichia coli str. K-12 substr. DH10B 6062337 YP_001730573.1 CDS ynfG NC_010473.1 1751975 1752592 D oxidoreductase, Fe-S subunit 1751975..1752592 Escherichia coli str. K-12 substr. DH10B 6062267 YP_001730574.1 CDS ynfH NC_010473.1 1752594 1753448 D oxidoreductase, membrane subunit 1752594..1753448 Escherichia coli str. K-12 substr. DH10B 6062252 YP_001730575.1 CDS dmsD NC_010473.1 1753491 1754105 D binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 1753491..1754105 Escherichia coli str. K-12 substr. DH10B 6062318 YP_001730576.1 CDS clcB NC_010473.1 1754300 1755556 D putative voltage-gated ClC-type chloride channel ClcB 1754300..1755556 Escherichia coli str. K-12 substr. DH10B 6058655 YP_001730577.1 CDS ynfK NC_010473.1 1755509 1756204 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; putative dithiobiotin synthetase complement(1755509..1756204) Escherichia coli str. K-12 substr. DH10B 6058911 YP_001730578.1 CDS dgsA NC_010473.1 1756329 1757549 R DNA-binding transcriptional repressor complement(1756329..1757549) Escherichia coli str. K-12 substr. DH10B 6059088 YP_001730579.1 CDS ynfL NC_010473.1 1757684 1758577 R DNA-binding transcriptional regulator complement(1757684..1758577) Escherichia coli str. K-12 substr. DH10B 6058974 YP_001730580.1 CDS ynfM NC_010473.1 1758684 1759937 D transporter 1758684..1759937 Escherichia coli str. K-12 substr. DH10B 6059570 YP_001730581.1 CDS asr NC_010473.1 1760361 1760669 D required for growth and survival under moderately acid conditions; acid shock protein 1760361..1760669 Escherichia coli str. K-12 substr. DH10B 6060319 YP_001730582.1 CDS ydgD NC_010473.1 1760945 1761766 D peptidase 1760945..1761766 Escherichia coli str. K-12 substr. DH10B 6060397 YP_001730583.1 CDS mdtI NC_010473.1 1761805 1762134 R with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI complement(1761805..1762134) Escherichia coli str. K-12 substr. DH10B 6059262 YP_001730584.1 CDS mdtJ NC_010473.1 1762121 1762486 R with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtJ complement(1762121..1762486) Escherichia coli str. K-12 substr. DH10B 6059237 YP_001730585.1 CDS tqsA NC_010473.1 1762898 1763932 D transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; putative transport protein 1762898..1763932 Escherichia coli str. K-12 substr. DH10B 6059165 YP_001730586.1 CDS pntB NC_010473.1 1763957 1765345 R catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase complement(1763957..1765345) Escherichia coli str. K-12 substr. DH10B 6059009 YP_001730587.1 CDS pntA NC_010473.1 1765356 1766888 R forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha complement(1765356..1766888) Escherichia coli str. K-12 substr. DH10B 6058971 YP_001730588.1 CDS ydgH NC_010473.1 1767412 1768356 D hypothetical protein 1767412..1768356 Escherichia coli str. K-12 substr. DH10B 6058690 YP_001730589.1 CDS ydgI NC_010473.1 1768542 1769924 D arginine/ornithine transporter 1768542..1769924 Escherichia coli str. K-12 substr. DH10B 6058681 YP_001730590.1 CDS folM NC_010473.1 1769961 1770683 D short chain dehydrogenase 1769961..1770683 Escherichia coli str. K-12 substr. DH10B 6059380 YP_001730591.1 CDS ydgC NC_010473.1 1770680 1771015 R inner membrane protein associated with alginate biosynthesis complement(1770680..1771015) Escherichia coli str. K-12 substr. DH10B 6059789 YP_001730592.1 CDS rstA NC_010473.1 1771135 1771863 D response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 1771135..1771863 Escherichia coli str. K-12 substr. DH10B 6059238 YP_001730593.1 CDS rstB NC_010473.1 1771867 1773168 D sensor protein RstB 1771867..1773168 Escherichia coli str. K-12 substr. DH10B 6059453 YP_001730594.1 CDS tus NC_010473.1 1773244 1774173 D binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 1773244..1774173 Escherichia coli str. K-12 substr. DH10B 6060496 YP_001730595.1 CDS fumC NC_010473.1 1774170 1775573 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(1774170..1775573) Escherichia coli str. K-12 substr. DH10B 6059759 YP_001730596.1 CDS fumA NC_010473.1 1775716 1777362 R fumarate hydratase, aerobic class I complement(1775716..1777362) Escherichia coli str. K-12 substr. DH10B 6059791 YP_001730597.1 CDS manA NC_010473.1 1777561 1778736 D mannose-6-phosphate isomerase 1777561..1778736 Escherichia coli str. K-12 substr. DH10B 6059901 YP_001730598.1 CDS ydgA NC_010473.1 1778837 1780345 D hypothetical protein 1778837..1780345 Escherichia coli str. K-12 substr. DH10B 6061860 YP_001730599.1 CDS uidC NC_010473.1 1780571 1781836 R putative outer membrane porin protein complement(1780571..1781836) Escherichia coli str. K-12 substr. DH10B 6061886 YP_001730600.1 CDS uidB NC_010473.1 1781875 1783248 R glucuronide transporter complement(1781875..1783248) Escherichia coli str. K-12 substr. DH10B 6061776 YP_001730601.1 CDS uidA NC_010473.1 1783245 1785056 R beta-D-glucuronidase complement(1783245..1785056) Escherichia coli str. K-12 substr. DH10B 6061790 YP_001730602.1 CDS uidR NC_010473.1 1785447 1786037 R DNA-binding transcriptional repressor complement(1785447..1786037) Escherichia coli str. K-12 substr. DH10B 6061806 YP_001730603.1 CDS hdhA NC_010473.1 1786258 1787025 R Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase complement(1786258..1787025) Escherichia coli str. K-12 substr. DH10B 6061820 YP_001730604.1 CDS malI NC_010473.1 1787137 1788165 R regulates malXY which are involved in maltose-glucose transport; DNA-binding transcriptional repressor MalI complement(1787137..1788165) Escherichia coli str. K-12 substr. DH10B 6061821 YP_001730605.1 CDS malX NC_010473.1 1788340 1789932 D phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site; bifunctional PTS system maltose and glucose-specific transporter subunits IICB 1788340..1789932 Escherichia coli str. K-12 substr. DH10B 6061823 YP_001730606.1 CDS malY NC_010473.1 1789942 1791114 D bifunctional beta-cystathionase and regulator of maltose regulon 1789942..1791114 Escherichia coli str. K-12 substr. DH10B 6061827 YP_001730607.1 CDS add NC_010473.1 1791218 1792219 D catalyzes the formation of inosine from adenosine; adenosine deaminase 1791218..1792219 Escherichia coli str. K-12 substr. DH10B 6061844 YP_001730608.1 CDS ydgJ NC_010473.1 1792253 1793293 R putative oxidoreductase complement(1792253..1793293) Escherichia coli str. K-12 substr. DH10B 6061854 YP_001730609.1 CDS ydgT NC_010473.1 1793544 1793759 D YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 1793544..1793759 Escherichia coli str. K-12 substr. DH10B 6061857 YP_001730610.1 CDS ydgK NC_010473.1 1793845 1794285 D inner membrane protein 1793845..1794285 Escherichia coli str. K-12 substr. DH10B 6061858 YP_001730611.1 CDS rsxA NC_010473.1 1794362 1794943 D Na(+)-translocating NADH-quinone reductase subunit E 1794362..1794943 Escherichia coli str. K-12 substr. DH10B 6061862 YP_001730612.1 CDS rsxB NC_010473.1 1794943 1795521 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1794943..1795521 Escherichia coli str. K-12 substr. DH10B 6061863 YP_001730613.1 CDS rsxC NC_010473.1 1795514 1797736 D part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1795514..1797736 Escherichia coli str. K-12 substr. DH10B 6061864 YP_001730614.1 CDS rnfD NC_010473.1 1797737 1798795 D RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1797737..1798795 Escherichia coli str. K-12 substr. DH10B 6061875 YP_001730615.1 CDS rsxG NC_010473.1 1798799 1799419 D part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1798799..1799419 Escherichia coli str. K-12 substr. DH10B 6061879 YP_001730616.1 CDS rsxE NC_010473.1 1799423 1800118 D in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE 1799423..1800118 Escherichia coli str. K-12 substr. DH10B 6061883 YP_001730617.1 CDS nth NC_010473.1 1800118 1800753 D DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 1800118..1800753 Escherichia coli str. K-12 substr. DH10B 6061884 YP_001730618.1 CDS tppB NC_010473.1 1801364 1802866 D mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; putative tripeptide transporter permease 1801364..1802866 Escherichia coli str. K-12 substr. DH10B 6061889 YP_001730619.1 CDS gst NC_010473.1 1802972 1803577 D glutathionine S-transferase 1802972..1803577 Escherichia coli str. K-12 substr. DH10B 6061899 YP_001730620.1 CDS pdxY NC_010473.1 1803621 1804484 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase complement(1803621..1804484) Escherichia coli str. K-12 substr. DH10B 6061906 YP_001730621.1 CDS tyrS NC_010473.1 1804543 1805817 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(1804543..1805817) Escherichia coli str. K-12 substr. DH10B 6061908 YP_001730622.1 CDS pdxH NC_010473.1 1805946 1806602 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase complement(1805946..1806602) Escherichia coli str. K-12 substr. DH10B 6061926 YP_001730623.1 CDS ydhA NC_010473.1 1806661 1806990 R MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor complement(1806661..1806990) Escherichia coli str. K-12 substr. DH10B 6061931 YP_001730624.1 CDS anmK NC_010473.1 1807088 1808197 R catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase complement(1807088..1808197) Escherichia coli str. K-12 substr. DH10B 6061940 YP_001730625.1 CDS slyB NC_010473.1 1808471 1808938 D outer membrane lipoprotein 1808471..1808938 Escherichia coli str. K-12 substr. DH10B 6061942 YP_001730626.1 CDS slyA NC_010473.1 1808985 1809419 R Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA complement(1808985..1809419) Escherichia coli str. K-12 substr. DH10B 6061949 YP_001730627.1 CDS ydhJ NC_010473.1 1809859 1810716 D undecaprenyl pyrophosphate phosphatase 1809859..1810716 Escherichia coli str. K-12 substr. DH10B 6061954 YP_001730628.1 CDS ydhK NC_010473.1 1810716 1812728 D inner membrane protein 1810716..1812728 Escherichia coli str. K-12 substr. DH10B 6061965 YP_001730629.1 CDS sodC NC_010473.1 1812729 1813250 R SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase complement(1812729..1813250) Escherichia coli str. K-12 substr. DH10B 6061966 YP_001730630.1 CDS ydhF NC_010473.1 1813331 1814227 R oxidoreductase complement(1813331..1814227) Escherichia coli str. K-12 substr. DH10B 6061967 YP_001730631.1 CDS ydhL NC_010473.1 1814276 1814515 R hypothetical protein complement(1814276..1814515) Escherichia coli str. K-12 substr. DH10B 6061988 YP_001730632.1 CDS ydhM NC_010473.1 1814702 1815217 D DNA-binding transcriptional regulator 1814702..1815217 Escherichia coli str. K-12 substr. DH10B 6061992 YP_001730633.1 CDS nemA NC_010473.1 1815254 1816351 D FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 1815254..1816351 Escherichia coli str. K-12 substr. DH10B 6061996 YP_001730634.1 CDS gloA NC_010473.1 1816432 1816839 D Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 1816432..1816839 Escherichia coli str. K-12 substr. DH10B 6062001 YP_001730635.1 CDS rnt NC_010473.1 1816942 1817589 D Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 1816942..1817589 Escherichia coli str. K-12 substr. DH10B 6062002 YP_001730636.1 CDS lhr NC_010473.1 1817682 1822298 D similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases; longest known protein in E. coli; putative ATP-dependent helicase Lhr 1817682..1822298 Escherichia coli str. K-12 substr. DH10B 6062015 YP_001730637.1 CDS grxD NC_010473.1 1822349 1822696 R hypothetical protein complement(1822349..1822696) Escherichia coli str. K-12 substr. DH10B 6062018 YP_001730638.1 CDS ydhO NC_010473.1 1823030 1823845 D lipoprotein 1823030..1823845 Escherichia coli str. K-12 substr. DH10B 6062022 YP_001730639.1 CDS sodB NC_010473.1 1823973 1824554 D SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 1823973..1824554 Escherichia coli str. K-12 substr. DH10B 6062033 YP_001730640.1 CDS ydhP NC_010473.1 1824716 1825885 R transporter complement(1824716..1825885) Escherichia coli str. K-12 substr. DH10B 6062038 YP_001730641.1 CDS ydhB NC_010473.1 1827461 1828393 R putative DNA-binding transcriptional regulator complement(1827461..1828393) Escherichia coli str. K-12 substr. DH10B 6062056 YP_001730642.1 CDS ydhC NC_010473.1 1828506 1829717 D uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 1828506..1829717 Escherichia coli str. K-12 substr. DH10B 6062066 YP_001730643.1 CDS cfa NC_010473.1 1830008 1831156 D catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane-fatty-acyl-phospholipid synthase 1830008..1831156 Escherichia coli str. K-12 substr. DH10B 6062082 YP_001730644.1 CDS ribC NC_010473.1 1831196 1831837 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(1831196..1831837) Escherichia coli str. K-12 substr. DH10B 6062086 YP_001730645.1 CDS mdtK NC_010473.1 1832052 1833425 D NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1832052..1833425 Escherichia coli str. K-12 substr. DH10B 6062087 YP_001730646.1 CDS ydhQ NC_010473.1 1833466 1834722 R hypothetical protein complement(1833466..1834722) Escherichia coli str. K-12 substr. DH10B 6062088 YP_001730647.1 CDS ydhR NC_010473.1 1835295 1835600 D hypothetical protein 1835295..1835600 Escherichia coli str. K-12 substr. DH10B 6061680 YP_001730648.1 CDS ydhS NC_010473.1 1835726 1837330 D hypothetical protein 1835726..1837330 Escherichia coli str. K-12 substr. DH10B 6062100 YP_001730649.1 CDS ydhT NC_010473.1 1837342 1838154 R hypothetical protein complement(1837342..1838154) Escherichia coli str. K-12 substr. DH10B 6062104 YP_001730650.1 CDS ydhU NC_010473.1 1838158 1838943 R cytochrome complement(1838158..1838943) Escherichia coli str. K-12 substr. DH10B 6062117 YP_001730651.1 CDS ydhX NC_010473.1 1838940 1839608 R 4Fe-4S ferredoxin complement(1838940..1839608) Escherichia coli str. K-12 substr. DH10B 6062124 YP_001730652.1 CDS ydhW NC_010473.1 1839672 1840319 R hypothetical protein complement(1839672..1840319) Escherichia coli str. K-12 substr. DH10B 6062133 YP_001730653.1 CDS ydhV NC_010473.1 1840323 1842425 R putative oxidoreductase complement(1840323..1842425) Escherichia coli str. K-12 substr. DH10B 6062138 YP_001730654.1 CDS ydhY NC_010473.1 1842446 1843072 R hypothetical protein complement(1842446..1843072) Escherichia coli str. K-12 substr. DH10B 6062139 YP_001730655.1 CDS ydhZ NC_010473.1 1843527 1843736 R hypothetical protein complement(1843527..1843736) Escherichia coli str. K-12 substr. DH10B 6062140 YP_001730656.1 CDS pykF NC_010473.1 1844293 1845705 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1844293..1845705 Escherichia coli str. K-12 substr. DH10B 6062142 YP_001730657.1 CDS lpp NC_010473.1 1846016 1846252 D murein lipoprotein 1846016..1846252 Escherichia coli str. K-12 substr. DH10B 6062143 YP_001730658.1 CDS ynhG NC_010473.1 1846316 1847320 R hypothetical protein complement(1846316..1847320) Escherichia coli str. K-12 substr. DH10B 6062149 YP_001730659.1 CDS sufE NC_010473.1 1847469 1847885 R Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE complement(1847469..1847885) Escherichia coli str. K-12 substr. DH10B 6062155 YP_001730660.1 CDS sufS NC_010473.1 1847898 1849118 R catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase complement(1847898..1849118) Escherichia coli str. K-12 substr. DH10B 6062160 YP_001730661.1 CDS sufD NC_010473.1 1849115 1850386 R with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD complement(1849115..1850386) Escherichia coli str. K-12 substr. DH10B 6062161 YP_001730662.1 CDS sufC NC_010473.1 1850361 1851107 R part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase complement(1850361..1851107) Escherichia coli str. K-12 substr. DH10B 6062162 YP_001730663.1 CDS sufB NC_010473.1 1851117 1852604 R with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB complement(1851117..1852604) Escherichia coli str. K-12 substr. DH10B 6062166 YP_001730664.1 CDS sufA NC_010473.1 1852613 1852981 R functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein complement(1852613..1852981) Escherichia coli str. K-12 substr. DH10B 6062171 YP_001730665.1 CDS ydiH NC_010473.1 1853529 1853798 R hypothetical protein complement(1853529..1853798) Escherichia coli str. K-12 substr. DH10B 6059715 YP_001730666.1 CDS ydiI NC_010473.1 1853817 1854227 R hypothetical protein complement(1853817..1854227) Escherichia coli str. K-12 substr. DH10B 6062178 YP_001730667.1 CDS ydiJ NC_010473.1 1854224 1857280 R FAD-linked oxidoreductase complement(1854224..1857280) Escherichia coli str. K-12 substr. DH10B 6062181 YP_001730668.1 CDS ydiK NC_010473.1 1857669 1858781 D YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; putative inner membrane protein 1857669..1858781 Escherichia coli str. K-12 substr. DH10B 6062182 YP_001730669.1 CDS ydiL NC_010473.1 1859210 1859566 D hypothetical protein 1859210..1859566 Escherichia coli str. K-12 substr. DH10B 6059270 YP_001730670.1 CDS ydiM NC_010473.1 1859666 1860880 D transporter 1859666..1860880 Escherichia coli str. K-12 substr. DH10B 6062190 YP_001730671.1 CDS ydiN NC_010473.1 1861107 1862372 D transporter 1861107..1862372 Escherichia coli str. K-12 substr. DH10B 6062192 YP_001730672.1 CDS ydiB NC_010473.1 1862384 1863250 D YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate; quinate/shikimate dehydrogenase 1862384..1863250 Escherichia coli str. K-12 substr. DH10B 6062193 YP_001730673.1 CDS aroD NC_010473.1 1863281 1864039 D catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 1863281..1864039 Escherichia coli str. K-12 substr. DH10B 6062211 YP_001730674.1 CDS ydiO NC_010473.1 1865791 1866942 D may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; putative acyl-CoA dehydrogenase 1865791..1866942 Escherichia coli str. K-12 substr. DH10B 6062216 YP_001730675.1 CDS ydiP NC_010473.1 1866985 1867896 R DNA-binding transcriptional regulator complement(1866985..1867896) Escherichia coli str. K-12 substr. DH10B 6062230 YP_001730676.1 CDS ydiQ NC_010473.1 1868212 1868976 D YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain; putative electron transfer flavoprotein YdiQ 1868212..1868976 Escherichia coli str. K-12 substr. DH10B 6062239 YP_001730677.1 CDS ydiR NC_010473.1 1868996 1869934 D May play a role in a redox process; electron transfer flavoprotein subunit YdiR 1868996..1869934 Escherichia coli str. K-12 substr. DH10B 6062241 YP_001730678.1 CDS ydiS NC_010473.1 1869990 1871279 D hypothetical protein 1869990..1871279 Escherichia coli str. K-12 substr. DH10B 6062257 YP_001730679.1 CDS ydiT NC_010473.1 1871276 1871569 D 4Fe-4S ferredoxin 1871276..1871569 Escherichia coli str. K-12 substr. DH10B 6062262 YP_001730680.1 CDS ydiD NC_010473.1 1871572 1873272 D acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids; short chain acyl-CoA synthetase 1871572..1873272 Escherichia coli str. K-12 substr. DH10B 6062271 YP_001730681.1 CDS pps NC_010473.1 1873329 1875707 R catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase complement(1873329..1875707) Escherichia coli str. K-12 substr. DH10B 6062273 YP_001730682.1 CDS ydiA NC_010473.1 1876040 1876873 D hypothetical protein 1876040..1876873 Escherichia coli str. K-12 substr. DH10B 6062277 YP_001730683.1 CDS aroH NC_010473.1 1877030 1878076 D tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 1877030..1878076 Escherichia coli str. K-12 substr. DH10B 6062284 YP_001730684.1 CDS ydiE NC_010473.1 1878208 1878399 D hypothetical protein 1878208..1878399 Escherichia coli str. K-12 substr. DH10B 6062287 YP_001730685.1 CDS ydiU NC_010473.1 1878403 1879839 R hypothetical protein complement(1878403..1879839) Escherichia coli str. K-12 substr. DH10B 6062293 YP_001730686.1 CDS ydiV NC_010473.1 1879902 1880615 R hypothetical protein complement(1879902..1880615) Escherichia coli str. K-12 substr. DH10B 6062298 YP_001730687.1 CDS nlpC NC_010473.1 1880862 1881326 R lipoprotein complement(1880862..1881326) Escherichia coli str. K-12 substr. DH10B 6062307 YP_001730688.1 CDS btuD NC_010473.1 1881404 1882153 R ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase complement(1881404..1882153) Escherichia coli str. K-12 substr. DH10B 6062322 YP_001730689.1 CDS btuE NC_010473.1 1882153 1882704 R similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; putative glutathione peroxidase complement(1882153..1882704) Escherichia coli str. K-12 substr. DH10B 6062364 YP_001730690.1 CDS btuC NC_010473.1 1882767 1883747 R with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease complement(1882767..1883747) Escherichia coli str. K-12 substr. DH10B 6062370 YP_001730691.1 CDS ihfA NC_010473.1 1883848 1884147 R This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha complement(1883848..1884147) Escherichia coli str. K-12 substr. DH10B 6062397 YP_001730692.1 CDS pheT NC_010473.1 1884152 1886539 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(1884152..1886539) Escherichia coli str. K-12 substr. DH10B 6059612 YP_001730693.1 CDS pheS NC_010473.1 1886554 1887537 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha complement(1886554..1887537) Escherichia coli str. K-12 substr. DH10B 6059730 YP_001730695.1 CDS rplT NC_010473.1 1887988 1888344 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(1887988..1888344) Escherichia coli str. K-12 substr. DH10B 6062341 YP_001730696.1 CDS rpmI NC_010473.1 1888397 1888594 R 50S ribosomal protein L35 complement(1888397..1888594) Escherichia coli str. K-12 substr. DH10B 6059285 YP_001730697.1 CDS thrS NC_010473.1 1889237 1891165 R catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase complement(1889237..1891165) Escherichia coli str. K-12 substr. DH10B 6058835 YP_001730698.1 CDS yniD NC_010473.1 1893745 1893867 D hypothetical protein 1893745..1893867 Escherichia coli str. K-12 substr. DH10B 6059709 YP_001730699.1 CDS ydiY NC_010473.1 1893920 1894678 R hypothetical protein complement(1893920..1894678) Escherichia coli str. K-12 substr. DH10B 6059105 YP_001730700.1 CDS pfkB NC_010473.1 1894965 1895894 D 6-phosphofructokinase 1894965..1895894 Escherichia coli str. K-12 substr. DH10B 6059131 YP_001730701.1 CDS ydiZ NC_010473.1 1895995 1896285 D hypothetical protein 1895995..1896285 Escherichia coli str. K-12 substr. DH10B 6059718 YP_001730702.1 CDS yniA NC_010473.1 1896391 1897251 D phosphotransferase/kinase 1896391..1897251 Escherichia coli str. K-12 substr. DH10B 6060197 YP_001730703.1 CDS yniB NC_010473.1 1897292 1897828 R inner membrane protein complement(1897292..1897828) Escherichia coli str. K-12 substr. DH10B 6058864 YP_001730704.1 CDS yniC NC_010473.1 1897975 1898643 D YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 1897975..1898643 Escherichia coli str. K-12 substr. DH10B 6060331 YP_001730705.1 CDS ydjM NC_010473.1 1898806 1899396 D hypothetical protein 1898806..1899396 Escherichia coli str. K-12 substr. DH10B 6059768 YP_001730706.1 CDS ydjN NC_010473.1 1899529 1900920 D transporter 1899529..1900920 Escherichia coli str. K-12 substr. DH10B 6060162 YP_001730707.1 CDS ydjO NC_010473.1 1900924 1901739 R hypothetical protein complement(1900924..1901739) Escherichia coli str. K-12 substr. DH10B 6058710 YP_001730708.1 CDS cedA NC_010473.1 1902016 1902279 R cell division modulator complement(1902016..1902279) Escherichia coli str. K-12 substr. DH10B 6058674 YP_001730709.1 CDS katE NC_010473.1 1902462 1904723 D Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 1902462..1904723 Escherichia coli str. K-12 substr. DH10B 6062391 YP_001730710.1 CDS chbG NC_010473.1 1904981 1905730 R hypothetical protein complement(1904981..1905730) Escherichia coli str. K-12 substr. DH10B 6062385 YP_001730711.1 CDS chbF NC_010473.1 1905743 1907095 R cryptic phospho-beta-glucosidase, NAD(P)-binding complement(1905743..1907095) Escherichia coli str. K-12 substr. DH10B 6058781 YP_001730712.1 CDS chbR NC_010473.1 1907200 1908042 R represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR complement(1907200..1908042) Escherichia coli str. K-12 substr. DH10B 6058689 YP_001730713.1 CDS chbA NC_010473.1 1908050 1908400 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA complement(1908050..1908400) Escherichia coli str. K-12 substr. DH10B 6062276 YP_001730714.1 CDS chbC NC_010473.1 1908451 1909809 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC complement(1908451..1909809) Escherichia coli str. K-12 substr. DH10B 6059142 YP_001730715.1 CDS chbB NC_010473.1 1909894 1910214 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB complement(1909894..1910214) Escherichia coli str. K-12 substr. DH10B 6059143 YP_001730716.1 CDS osmE NC_010473.1 1910513 1910851 R osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE complement(1910513..1910851) Escherichia coli str. K-12 substr. DH10B 6059139 YP_001730717.1 CDS nadE NC_010473.1 1911053 1911880 D catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1911053..1911880 Escherichia coli str. K-12 substr. DH10B 6059160 YP_001730718.1 CDS cho NC_010473.1 1912110 1912997 D 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 1912110..1912997 Escherichia coli str. K-12 substr. DH10B 6062274 YP_001730719.1 CDS ydjR NC_010473.1 1912957 1913532 R hypothetical protein complement(1912957..1913532) Escherichia coli str. K-12 substr. DH10B 6062248 YP_001730720.1 CDS spy NC_010473.1 1913735 1914220 R periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; hypothetical protein complement(1913735..1914220) Escherichia coli str. K-12 substr. DH10B 6062326 YP_001730721.1 CDS astE NC_010473.1 1914550 1915518 R catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase complement(1914550..1915518) Escherichia coli str. K-12 substr. DH10B 6062421 YP_001730722.1 CDS astB NC_010473.1 1915511 1916854 R catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase complement(1915511..1916854) Escherichia coli str. K-12 substr. DH10B 6062313 YP_001730723.1 CDS astD NC_010473.1 1916851 1918329 R a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase complement(1916851..1918329) Escherichia coli str. K-12 substr. DH10B 6061505 YP_001730724.1 CDS astA NC_010473.1 1918326 1919360 R arginine succinyltransferase complement(1918326..1919360) Escherichia coli str. K-12 substr. DH10B 6060726 YP_001730725.1 CDS astC NC_010473.1 1919357 1920577 R catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase complement(1919357..1920577) Escherichia coli str. K-12 substr. DH10B 6060730 YP_001730726.1 CDS xthA NC_010473.1 1921023 1921829 D removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1921023..1921829 Escherichia coli str. K-12 substr. DH10B 6060661 YP_001730727.1 CDS ydjX NC_010473.1 1921996 1922706 D inner membrane protein 1921996..1922706 Escherichia coli str. K-12 substr. DH10B 6061486 YP_001730728.1 CDS ydjY NC_010473.1 1922711 1923388 D hypothetical protein 1922711..1923388 Escherichia coli str. K-12 substr. DH10B 6061432 YP_001730729.1 CDS ydjZ NC_010473.1 1923403 1924110 D inner membrane protein 1923403..1924110 Escherichia coli str. K-12 substr. DH10B 6061540 YP_001730730.1 CDS ynjA NC_010473.1 1924110 1924658 D hypothetical protein 1924110..1924658 Escherichia coli str. K-12 substr. DH10B 6061538 YP_001730731.1 CDS ynjB NC_010473.1 1924668 1925834 D putative ABC transporter solute-binding protein 1924668..1925834 Escherichia coli str. K-12 substr. DH10B 6061412 YP_001730732.1 CDS ynjC NC_010473.1 1925852 1927342 D ABC transporter membrane protein 1925852..1927342 Escherichia coli str. K-12 substr. DH10B 6061571 YP_001730733.1 CDS ynjD NC_010473.1 1927342 1927995 D ABC transporter ATP-binding protein 1927342..1927995 Escherichia coli str. K-12 substr. DH10B 6061578 YP_001730734.1 CDS ynjE NC_010473.1 1928062 1929369 D thiosulfate sulfur transferase 1928062..1929369 Escherichia coli str. K-12 substr. DH10B 6060676 YP_001730735.1 CDS ynjF NC_010473.1 1929378 1929998 R phosphatidyl transferase, inner membrane protein complement(1929378..1929998) Escherichia coli str. K-12 substr. DH10B 6060623 YP_001730736.1 CDS nudG NC_010473.1 1930085 1930492 D pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 1930085..1930492 Escherichia coli str. K-12 substr. DH10B 6060619 YP_001730737.1 CDS ynjH NC_010473.1 1930458 1930730 R hypothetical protein complement(1930458..1930730) Escherichia coli str. K-12 substr. DH10B 6061518 YP_001730738.1 CDS gdhA NC_010473.1 1930966 1932309 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1930966..1932309 Escherichia coli str. K-12 substr. DH10B 6061597 YP_001730739.1 CDS ynjI NC_010473.1 1932426 1933466 R hypothetical protein complement(1932426..1933466) Escherichia coli str. K-12 substr. DH10B 6061638 YP_001730740.1 CDS topB NC_010473.1 1933594 1935555 R decatenates replicating daughter chromosomes; DNA topoisomerase III complement(1933594..1935555) Escherichia coli str. K-12 substr. DH10B 6061647 YP_001730741.1 CDS selD NC_010473.1 1935560 1936603 R catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase complement(1935560..1936603) Escherichia coli str. K-12 substr. DH10B 6061609 YP_001730742.1 CDS ydjA NC_010473.1 1936720 1937271 R hypothetical protein complement(1936720..1937271) Escherichia coli str. K-12 substr. DH10B 6061570 YP_001730743.1 CDS sppA NC_010473.1 1937432 1939288 D SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 1937432..1939288 Escherichia coli str. K-12 substr. DH10B 6061621 YP_001730744.1 CDS ansA NC_010473.1 1939455 1940471 D converts asparagine to aspartate and ammonia; asparaginase 1939455..1940471 Escherichia coli str. K-12 substr. DH10B 6061673 YP_001730745.1 CDS pncA NC_010473.1 1940482 1941123 D catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 1940482..1941123 Escherichia coli str. K-12 substr. DH10B 6060567 YP_001730746.1 CDS ydjE NC_010473.1 1941216 1942574 R transporter complement(1941216..1942574) Escherichia coli str. K-12 substr. DH10B 6061675 YP_001730747.1 CDS ydjF NC_010473.1 1942691 1943449 R DNA-binding transcriptional regulator complement(1942691..1943449) Escherichia coli str. K-12 substr. DH10B 6061646 YP_001730748.1 CDS ydjG NC_010473.1 1943586 1944566 R oxidoreductase complement(1943586..1944566) Escherichia coli str. K-12 substr. DH10B 6060846 YP_001730749.1 CDS ydjH NC_010473.1 1944576 1945523 R kinase complement(1944576..1945523) Escherichia coli str. K-12 substr. DH10B 6061700 YP_001730750.1 CDS ydjJ NC_010473.1 1946385 1947428 R oxidoreductase, Zn-dependent and NAD(P)-binding complement(1946385..1947428) Escherichia coli str. K-12 substr. DH10B 6062357 YP_001730751.1 CDS ydjK NC_010473.1 1947445 1948824 R transporter complement(1947445..1948824) Escherichia coli str. K-12 substr. DH10B 6061684 YP_001730752.1 CDS ydjL NC_010473.1 1948851 1949927 R oxidoreductase, Zn-dependent and NAD(P)-binding complement(1948851..1949927) Escherichia coli str. K-12 substr. DH10B 6061726 YP_001730753.1 CDS yeaC NC_010473.1 1950297 1950569 R hypothetical protein complement(1950297..1950569) Escherichia coli str. K-12 substr. DH10B 6061739 YP_001730754.1 CDS msrB NC_010473.1 1950611 1951024 R this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B complement(1950611..1951024) Escherichia coli str. K-12 substr. DH10B 6060773 YP_001730755.1 CDS gapA NC_010473.1 1951366 1952361 D glyceraldehyde-3-phosphate dehydrogenase 1951366..1952361 Escherichia coli str. K-12 substr. DH10B 6061690 YP_001730756.1 CDS yeaD NC_010473.1 1952445 1953329 D hypothetical protein 1952445..1953329 Escherichia coli str. K-12 substr. DH10B 6061639 YP_001730757.1 CDS yeaE NC_010473.1 1953377 1954231 R oxidoreductase complement(1953377..1954231) Escherichia coli str. K-12 substr. DH10B 6062409 YP_001730758.1 CDS mipA NC_010473.1 1954321 1955067 R scaffolding protein for murein synthesizing machinery complement(1954321..1955067) Escherichia coli str. K-12 substr. DH10B 6061730 YP_001730759.1 CDS yeaG NC_010473.1 1955503 1957437 D hypothetical protein 1955503..1957437 Escherichia coli str. K-12 substr. DH10B 6061786 YP_001730760.1 CDS yeaH NC_010473.1 1957550 1958833 D hypothetical protein 1957550..1958833 Escherichia coli str. K-12 substr. DH10B 6060899 YP_001730761.1 CDS yeaI NC_010473.1 1958980 1960455 D diguanylate cyclase 1958980..1960455 Escherichia coli str. K-12 substr. DH10B 6061800 YP_001730762.1 CDS yeaJ NC_010473.1 1960636 1962126 D diguanylate cyclase 1960636..1962126 Escherichia coli str. K-12 substr. DH10B 6061861 YP_001730763.1 CDS yeaK NC_010473.1 1962169 1962672 D hypothetical protein 1962169..1962672 Escherichia coli str. K-12 substr. DH10B 6061873 YP_001730764.1 CDS yoaI NC_010473.1 1962673 1962777 R hypothetical protein complement(1962673..1962777) Escherichia coli str. K-12 substr. DH10B 6060824 YP_001730765.1 CDS yeaL NC_010473.1 1962947 1963393 D inner membrane protein 1962947..1963393 Escherichia coli str. K-12 substr. DH10B 6061890 YP_001730766.1 CDS yeaM NC_010473.1 1963350 1964171 R DNA-binding transcriptional regulator complement(1963350..1964171) Escherichia coli str. K-12 substr. DH10B 6061851 YP_001730767.1 CDS yeaN NC_010473.1 1964268 1965449 D transporter 1964268..1965449 Escherichia coli str. K-12 substr. DH10B 6061816 YP_001730768.1 CDS yeaO NC_010473.1 1965504 1965851 D hypothetical protein 1965504..1965851 Escherichia coli str. K-12 substr. DH10B 6061735 YP_001730769.1 CDS yoaF NC_010473.1 1965873 1966127 R outer membrane protein complement(1965873..1966127) Escherichia coli str. K-12 substr. DH10B 6061888 YP_001730770.1 CDS yeaP NC_010473.1 1966310 1967335 D diguanylate cyclase 1966310..1967335 Escherichia coli str. K-12 substr. DH10B 6060603 YP_001730771.1 CDS yeaQ NC_010473.1 1967602 1967850 R hypothetical protein complement(1967602..1967850) Escherichia coli str. K-12 substr. DH10B 6060605 YP_001730772.1 CDS yoaG NC_010473.1 1967998 1968180 R hypothetical protein complement(1967998..1968180) Escherichia coli str. K-12 substr. DH10B 6061796 YP_001730773.1 CDS yeaR NC_010473.1 1968184 1968543 R hypothetical protein complement(1968184..1968543) Escherichia coli str. K-12 substr. DH10B 6061892 YP_001730774.1 CDS yeaS NC_010473.1 1968716 1969354 R leucine export protein LeuE complement(1968716..1969354) Escherichia coli str. K-12 substr. DH10B 6061917 YP_001730775.1 CDS yeaT NC_010473.1 1969481 1970404 R DNA-binding transcriptional regulator complement(1969481..1970404) Escherichia coli str. K-12 substr. DH10B 6061896 YP_001730776.1 CDS yeaU NC_010473.1 1970507 1971592 D dehydrogenase 1970507..1971592 Escherichia coli str. K-12 substr. DH10B 6060908 YP_001730777.1 CDS yeaV NC_010473.1 1971783 1973228 D member of the betaine, carnitine, choline transporter (BCCT) family; unknown function; putative transporter 1971783..1973228 Escherichia coli str. K-12 substr. DH10B 6060973 YP_001730778.1 CDS yeaW NC_010473.1 1973260 1974384 D 2Fe-2S cluster-containing protein 1973260..1974384 Escherichia coli str. K-12 substr. DH10B 6060925 YP_001730779.1 CDS yeaX NC_010473.1 1974440 1975405 D oxidoreductase 1974440..1975405 Escherichia coli str. K-12 substr. DH10B 6060982 YP_001730780.1 CDS rnd NC_010473.1 1975459 1976586 R ribonuclease D complement(1975459..1976586) Escherichia coli str. K-12 substr. DH10B 6060625 YP_001730781.1 CDS fadD NC_010473.1 1976656 1978341 R Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(1976656..1978341) Escherichia coli str. K-12 substr. DH10B 6061811 YP_001730782.1 CDS yeaY NC_010473.1 1978546 1979127 R lipoprotein complement(1978546..1979127) Escherichia coli str. K-12 substr. DH10B 6060902 YP_001730783.1 CDS yeaZ NC_010473.1 1979167 1979862 R peptidase complement(1979167..1979862) Escherichia coli str. K-12 substr. DH10B 6061982 YP_001730784.1 CDS yoaA NC_010473.1 1979920 1981830 R hypothetical protein complement(1979920..1981830) Escherichia coli str. K-12 substr. DH10B 6060910 YP_001730785.1 CDS yoaB NC_010473.1 1981962 1982306 D hypothetical protein 1981962..1982306 Escherichia coli str. K-12 substr. DH10B 6062010 YP_001730786.1 CDS yoaC NC_010473.1 1982668 1983027 D hypothetical protein 1982668..1983027 Escherichia coli str. K-12 substr. DH10B 6060879 YP_001730787.1 CDS yoaH NC_010473.1 1983147 1983326 R hypothetical protein complement(1983147..1983326) Escherichia coli str. K-12 substr. DH10B 6061994 YP_001730788.1 CDS yeaB NC_010473.1 1984765 1985343 D hypothetical protein 1984765..1985343 Escherichia coli str. K-12 substr. DH10B 6062004 YP_001730789.1 CDS sdaA NC_010473.1 1985527 1986891 D L-serine deaminase I 1985527..1986891 Escherichia coli str. K-12 substr. DH10B 6061041 YP_001730790.1 CDS yoaD NC_010473.1 1987022 1988620 D phosphodiesterase 1987022..1988620 Escherichia coli str. K-12 substr. DH10B 6061010 YP_001730791.1 CDS yoaE NC_010473.1 1988624 1990180 R fused membrane protein; protein complement(1988624..1990180) Escherichia coli str. K-12 substr. DH10B 6062058 YP_001730792.1 CDS manX NC_010473.1 1990643 1991614 D fused mannose-specific PTS enzymes: IIA component; IIB component 1990643..1991614 Escherichia coli str. K-12 substr. DH10B 6062027 YP_001730793.1 CDS manY NC_010473.1 1991677 1992477 D mannose-specific enzyme IIC component of PTS 1991677..1992477 Escherichia coli str. K-12 substr. DH10B 6061060 YP_001730794.1 CDS manZ NC_010473.1 1992481 1993341 D hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 1992481..1993341 Escherichia coli str. K-12 substr. DH10B 6061024 YP_001730795.1 CDS yobD NC_010473.1 1993396 1993854 D hypothetical protein 1993396..1993854 Escherichia coli str. K-12 substr. DH10B 6062042 YP_001730796.1 CDS yebN NC_010473.1 1994283 1994849 D membrane protein YebN; hypothetical protein 1994283..1994849 Escherichia coli str. K-12 substr. DH10B 6062080 YP_001730797.1 CDS rrmA NC_010473.1 1994846 1995655 R methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase A complement(1994846..1995655) Escherichia coli str. K-12 substr. DH10B 6062016 YP_001730798.1 CDS cspC NC_010473.1 1995821 1996030 R cold shock-like protein CspC complement(1995821..1996030) Escherichia coli str. K-12 substr. DH10B 6062024 YP_001730799.1 CDS yobF NC_010473.1 1996043 1996186 R hypothetical protein complement(1996043..1996186) Escherichia coli str. K-12 substr. DH10B 6062026 YP_001730800.1 CDS yebO NC_010473.1 1996856 1997143 R hypothetical protein complement(1996856..1997143) Escherichia coli str. K-12 substr. DH10B 6061044 YP_001730801.1 CDS yobG NC_010473.1 1997218 1997361 R hypothetical protein complement(1997218..1997361) Escherichia coli str. K-12 substr. DH10B 6061099 YP_001730802.1 CDS yobH NC_010473.1 1997520 1997759 D hypothetical protein 1997520..1997759 Escherichia coli str. K-12 substr. DH10B 6062110 YP_001730803.1 CDS kdgR NC_010473.1 1997903 1998694 R DNA-binding transcriptional regulator complement(1997903..1998694) Escherichia coli str. K-12 substr. DH10B 6061002 YP_001730804.1 CDS yebQ NC_010473.1 1998871 2000244 D transporter 1998871..2000244 Escherichia coli str. K-12 substr. DH10B 6062048 YP_001730805.1 CDS htpX NC_010473.1 2000290 2001171 R putative metalloprotease; heat shock protein HtpX complement(2000290..2001171) Escherichia coli str. K-12 substr. DH10B 6062084 YP_001730806.1 CDS prc NC_010473.1 2001363 2003411 R Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease complement(2001363..2003411) Escherichia coli str. K-12 substr. DH10B 6061112 YP_001730807.1 CDS proQ NC_010473.1 2003431 2004129 R affects solute and DNA transport through an unknown mechanism; putative solute/DNA competence effector complement(2003431..2004129) Escherichia coli str. K-12 substr. DH10B 6062130 YP_001730808.1 CDS yebR NC_010473.1 2004226 2004777 R hypothetical protein complement(2004226..2004777) Escherichia coli str. K-12 substr. DH10B 6062098 YP_001730809.1 CDS yebS NC_010473.1 2004853 2006136 D inner membrane protein 2004853..2006136 Escherichia coli str. K-12 substr. DH10B 6061120 YP_001730810.1 CDS yebT NC_010473.1 2006105 2008738 D hypothetical protein 2006105..2008738 Escherichia coli str. K-12 substr. DH10B 6062113 YP_001730811.1 CDS yebU NC_010473.1 2008818 2010257 D in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 2008818..2010257 Escherichia coli str. K-12 substr. DH10B 6060501 YP_001730812.1 CDS yebV NC_010473.1 2010375 2010611 D hypothetical protein 2010375..2010611 Escherichia coli str. K-12 substr. DH10B 6060502 YP_001730813.1 CDS yebW NC_010473.1 2010716 2010907 D hypothetical protein 2010716..2010907 Escherichia coli str. K-12 substr. DH10B 6060559 YP_001730814.1 CDS pphA NC_010473.1 2010908 2011564 R Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 complement(2010908..2011564) Escherichia coli str. K-12 substr. DH10B 6060425 YP_001730815.1 CDS yebY NC_010473.1 2011960 2012301 R hypothetical protein complement(2011960..2012301) Escherichia coli str. K-12 substr. DH10B 6060951 YP_001730816.1 CDS yebZ NC_010473.1 2012314 2013186 R inner membrane protein complement(2012314..2013186) Escherichia coli str. K-12 substr. DH10B 6060556 YP_001730817.1 CDS yobA NC_010473.1 2013190 2013564 R hypothetical protein complement(2013190..2013564) Escherichia coli str. K-12 substr. DH10B 6060573 YP_001730818.1 CDS holE NC_010473.1 2013703 2013933 D DNA polymerase III subunit theta 2013703..2013933 Escherichia coli str. K-12 substr. DH10B 6060582 YP_001730819.1 CDS yobB NC_010473.1 2014035 2014691 D hypothetical protein 2014035..2014691 Escherichia coli str. K-12 substr. DH10B 6060727 YP_001730820.1 CDS exoX NC_010473.1 2014715 2015377 D 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 2014715..2015377 Escherichia coli str. K-12 substr. DH10B 6062232 YP_001730821.1 CDS ptrB NC_010473.1 2015374 2017434 R PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 complement(2015374..2017434) Escherichia coli str. K-12 substr. DH10B 6062424 YP_001730822.1 CDS yebE NC_010473.1 2017643 2018302 R hypothetical protein complement(2017643..2018302) Escherichia coli str. K-12 substr. DH10B 6062386 YP_001730823.1 CDS yebF NC_010473.1 2018629 2018997 R secreted protein; unknown function; hypothetical protein complement(2018629..2018997) Escherichia coli str. K-12 substr. DH10B 6062261 YP_001730824.1 CDS yebG NC_010473.1 2019052 2019342 R DNA damage-inducible protein YebG complement(2019052..2019342) Escherichia coli str. K-12 substr. DH10B 6062208 YP_001730825.1 CDS purT NC_010473.1 2019476 2020654 D non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 2019476..2020654 Escherichia coli str. K-12 substr. DH10B 6058146 YP_001730826.1 CDS eda NC_010473.1 2020710 2021351 R catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(2020710..2021351) Escherichia coli str. K-12 substr. DH10B 6058918 YP_001730827.1 CDS edd NC_010473.1 2021388 2023199 R catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase complement(2021388..2023199) Escherichia coli str. K-12 substr. DH10B 6060736 YP_001730828.1 CDS zwf NC_010473.1 2023434 2024909 R catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(2023434..2024909) Escherichia coli str. K-12 substr. DH10B 6059783 YP_001730829.1 CDS yebK NC_010473.1 2025247 2026116 D Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 2025247..2026116 Escherichia coli str. K-12 substr. DH10B 6060976 YP_001730830.1 CDS pykA NC_010473.1 2026244 2027686 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2026244..2027686 Escherichia coli str. K-12 substr. DH10B 6058790 YP_001730831.1 CDS lpxM NC_010473.1 2027817 2028788 R Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase complement(2027817..2028788) Escherichia coli str. K-12 substr. DH10B 6058856 YP_001730832.1 CDS yebA NC_010473.1 2028908 2030230 R hypothetical protein complement(2028908..2030230) Escherichia coli str. K-12 substr. DH10B 6059707 YP_001730833.1 CDS znuA NC_010473.1 2030246 2031178 R involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein complement(2030246..2031178) Escherichia coli str. K-12 substr. DH10B 6059992 YP_001730834.1 CDS znuC NC_010473.1 2031257 2032012 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 2031257..2032012 Escherichia coli str. K-12 substr. DH10B 6059673 YP_001730835.1 CDS znuB NC_010473.1 2032009 2032794 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane protein 2032009..2032794 Escherichia coli str. K-12 substr. DH10B 6060956 YP_001730836.1 CDS ruvB NC_010473.1 2032941 2033951 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(2032941..2033951) Escherichia coli str. K-12 substr. DH10B 6062332 YP_001730837.1 CDS ruvA NC_010473.1 2033960 2034571 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(2033960..2034571) Escherichia coli str. K-12 substr. DH10B 6060371 YP_001730838.1 CDS yebB NC_010473.1 2034846 2035448 D hypothetical protein 2034846..2035448 Escherichia coli str. K-12 substr. DH10B 6061958 YP_001730839.1 CDS ruvC NC_010473.1 2035450 2035971 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(2035450..2035971) Escherichia coli str. K-12 substr. DH10B 6058834 YP_001730840.1 CDS yebC NC_010473.1 2036006 2036746 R hypothetical protein complement(2036006..2036746) Escherichia coli str. K-12 substr. DH10B 6058231 YP_001730841.1 CDS ntpA NC_010473.1 2036775 2037227 R converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase complement(2036775..2037227) Escherichia coli str. K-12 substr. DH10B 6058236 YP_001730842.1 CDS aspS NC_010473.1 2037345 2039117 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(2037345..2039117) Escherichia coli str. K-12 substr. DH10B 6058283 YP_001730843.1 CDS yecD NC_010473.1 2039427 2039993 D hypothetical protein 2039427..2039993 Escherichia coli str. K-12 substr. DH10B 6058316 YP_001730844.1 CDS yecE NC_010473.1 2039990 2040808 D hypothetical protein 2039990..2040808 Escherichia coli str. K-12 substr. DH10B 6058352 YP_001730845.1 CDS yecN NC_010473.1 2040861 2041256 D inner membrane protein 2040861..2041256 Escherichia coli str. K-12 substr. DH10B 6058391 YP_001730846.1 CDS yecO NC_010473.1 2041297 2042040 D methyltransferase 2041297..2042040 Escherichia coli str. K-12 substr. DH10B 6058396 YP_001730847.1 CDS yecP NC_010473.1 2042037 2043008 D S-adenosyl-L-methionine-dependent methyltransferase 2042037..2043008 Escherichia coli str. K-12 substr. DH10B 6058227 YP_001730848.1 CDS torZ NC_010473.1 2043173 2045602 R trimethylamine N-oxide reductase system III, catalytic subunit complement(2043173..2045602) Escherichia coli str. K-12 substr. DH10B 6058416 YP_001730849.1 CDS torY NC_010473.1 2045627 2046727 R TMAO reductase III (TorYZ), cytochrome c-type subunit complement(2045627..2046727) Escherichia coli str. K-12 substr. DH10B 6058481 YP_001730850.1 CDS cutC NC_010473.1 2047115 2047861 R copper homeostasis protein CutC complement(2047115..2047861) Escherichia coli str. K-12 substr. DH10B 6058491 YP_001730851.1 CDS yecM NC_010473.1 2047875 2048441 R hypothetical protein complement(2047875..2048441) Escherichia coli str. K-12 substr. DH10B 6058516 YP_001730852.1 CDS argS NC_010473.1 2048657 2050390 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2048657..2050390 Escherichia coli str. K-12 substr. DH10B 6058537 YP_001730853.1 CDS yecT NC_010473.1 2050567 2051055 D hypothetical protein 2050567..2051055 Escherichia coli str. K-12 substr. DH10B 6060242 YP_001730854.1 CDS flhE NC_010473.1 2051175 2051567 R hypothetical protein complement(2051175..2051567) Escherichia coli str. K-12 substr. DH10B 6058559 YP_001730855.1 CDS flhA NC_010473.1 2051567 2053645 R membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA complement(2051567..2053645) Escherichia coli str. K-12 substr. DH10B 6058600 YP_001730856.1 CDS flhB NC_010473.1 2053638 2054786 R membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB complement(2053638..2054786) Escherichia coli str. K-12 substr. DH10B 6058614 YP_001730857.1 CDS cheZ NC_010473.1 2054988 2055632 R cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ complement(2054988..2055632) Escherichia coli str. K-12 substr. DH10B 6058615 YP_001730858.1 CDS cheY NC_010473.1 2055643 2056032 R chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY complement(2055643..2056032) Escherichia coli str. K-12 substr. DH10B 6058620 YP_001730859.1 CDS cheB NC_010473.1 2056047 2057096 R regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase complement(2056047..2057096) Escherichia coli str. K-12 substr. DH10B 6058625 YP_001730860.1 CDS cheR NC_010473.1 2057099 2057959 R methylates the MCP; chemotaxis methyltransferase CheR complement(2057099..2057959) Escherichia coli str. K-12 substr. DH10B 6058622 YP_001730861.1 CDS tap NC_010473.1 2057978 2059579 R mediates taxis toward dipeptides; methyl-accepting protein IV complement(2057978..2059579) Escherichia coli str. K-12 substr. DH10B 6058631 YP_001730862.1 CDS tar NC_010473.1 2059625 2061286 R methyl-accepting chemotaxis protein II complement(2059625..2061286) Escherichia coli str. K-12 substr. DH10B 6058628 YP_001730863.1 CDS cheW NC_010473.1 2061431 2061934 R purine-binding chemotaxis protein complement(2061431..2061934) Escherichia coli str. K-12 substr. DH10B 6058633 YP_001730864.1 CDS motB NC_010473.1 2063924 2064850 R protein that enables flagellar motor rotation; with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB complement(2063924..2064850) Escherichia coli str. K-12 substr. DH10B 6058648 YP_001730865.1 CDS motA NC_010473.1 2064847 2065734 R With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA complement(2064847..2065734) Escherichia coli str. K-12 substr. DH10B 6058650 YP_001730866.1 CDS flhD NC_010473.1 2066456 2066815 R with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD complement(2066456..2066815) Escherichia coli str. K-12 substr. DH10B 6058651 YP_001730867.1 CDS yecG NC_010473.1 2068785 2069213 D ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 2068785..2069213 Escherichia coli str. K-12 substr. DH10B 6058656 YP_001730868.1 CDS otsA NC_010473.1 2069220 2070644 R trehalose-6-phosphate synthase complement(2069220..2070644) Escherichia coli str. K-12 substr. DH10B 6058632 YP_001730869.1 CDS otsB NC_010473.1 2070619 2071419 R biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase complement(2070619..2071419) Escherichia coli str. K-12 substr. DH10B 6058660 YP_001730870.1 CDS araH NC_010473.1 2071586 2072575 R Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease complement(2071586..2072575) Escherichia coli str. K-12 substr. DH10B 6058663 YP_001730871.1 CDS araG NC_010473.1 2072587 2074101 R Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein complement(2072587..2074101) Escherichia coli str. K-12 substr. DH10B 6058669 YP_001730872.1 CDS araF NC_010473.1 2074171 2075160 R periplasmic-binding component of L-arabinose ABC transporter (precursor) complement(2074171..2075160) Escherichia coli str. K-12 substr. DH10B 6058822 YP_001730873.1 CDS yecI NC_010473.1 2075957 2076460 D ferritin-like protein 2075957..2076460 Escherichia coli str. K-12 substr. DH10B 6058672 YP_001730874.1 CDS yecJ NC_010473.1 2076539 2076790 R hypothetical protein complement(2076539..2076790) Escherichia coli str. K-12 substr. DH10B 6058696 YP_001730875.1 CDS yecR NC_010473.1 2077254 2077577 D hypothetical protein 2077254..2077577 Escherichia coli str. K-12 substr. DH10B 6058910 YP_001730876.1 CDS ftn NC_010473.1 2077748 2078245 D cytoplasmic iron storage protein; ferritin 2077748..2078245 Escherichia coli str. K-12 substr. DH10B 6058709 YP_001730877.1 CDS yecH NC_010473.1 2078283 2078522 R hypothetical protein complement(2078283..2078522) Escherichia coli str. K-12 substr. DH10B 6059659 YP_001730878.1 CDS tyrP NC_010473.1 2078713 2079924 D tyrosine transporter 2078713..2079924 Escherichia coli str. K-12 substr. DH10B 6059780 YP_001730879.1 CDS yecA NC_010473.1 2079986 2080651 R hypothetical protein complement(2079986..2080651) Escherichia coli str. K-12 substr. DH10B 6058717 YP_001730880.1 CDS pgsA NC_010473.1 2081301 2081849 R phosphatidylglycerophosphate synthetase complement(2081301..2081849) Escherichia coli str. K-12 substr. DH10B 6060196 YP_001730881.1 CDS uvrC NC_010473.1 2081906 2083738 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(2081906..2083738) Escherichia coli str. K-12 substr. DH10B 6058725 YP_001730882.1 CDS uvrY NC_010473.1 2083735 2084391 R in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator complement(2083735..2084391) Escherichia coli str. K-12 substr. DH10B 6058729 YP_001730883.1 CDS yecF NC_010473.1 2084850 2085074 D hypothetical protein 2084850..2085074 Escherichia coli str. K-12 substr. DH10B 6058734 YP_001730884.1 CDS sdiA NC_010473.1 2085142 2085864 R regulates genes involved in cell division; DNA-binding transcriptional activator SdiA complement(2085142..2085864) Escherichia coli str. K-12 substr. DH10B 6058780 YP_001730885.1 CDS yecC NC_010473.1 2086094 2086846 R putative amino-acid ABC transporter ATP-binding protein YecC complement(2086094..2086846) Escherichia coli str. K-12 substr. DH10B 6058786 YP_001730886.1 CDS yecS NC_010473.1 2086843 2087511 R ABC transporter membrane protein complement(2086843..2087511) Escherichia coli str. K-12 substr. DH10B 6058787 YP_001730887.1 CDS dcyD NC_010473.1 2087526 2088512 R catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase complement(2087526..2088512) Escherichia coli str. K-12 substr. DH10B 6058788 YP_001730888.1 CDS fliY NC_010473.1 2088617 2089417 R cystine transporter subunit complement(2088617..2089417) Escherichia coli str. K-12 substr. DH10B 6058789 YP_001730889.1 CDS fliZ NC_010473.1 2089505 2090056 R expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ complement(2089505..2090056) Escherichia coli str. K-12 substr. DH10B 6058809 YP_001730890.1 CDS fliA NC_010473.1 2090102 2090821 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor complement(2090102..2090821) Escherichia coli str. K-12 substr. DH10B 6058815 YP_001730891.1 CDS fliD NC_010473.1 2092904 2094310 D involved in flagellin assembly; flagellar capping protein 2092904..2094310 Escherichia coli str. K-12 substr. DH10B 6058818 YP_001730892.1 CDS fliS NC_010473.1 2094335 2094745 D flagellin specific chaperone; flagellar protein FliS 2094335..2094745 Escherichia coli str. K-12 substr. DH10B 6058841 YP_001730893.1 CDS fliT NC_010473.1 2094745 2095110 D binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 2094745..2095110 Escherichia coli str. K-12 substr. DH10B 6058847 YP_001730894.1 CDS amyA NC_010473.1 2095188 2096675 D converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 2095188..2096675 Escherichia coli str. K-12 substr. DH10B 6058848 YP_001730895.1 CDS yedD NC_010473.1 2096709 2097122 R hypothetical protein complement(2096709..2097122) Escherichia coli str. K-12 substr. DH10B 6058851 YP_001730896.1 CDS yedE NC_010473.1 2097309 2098514 D putative inner membrane protein 2097309..2098514 Escherichia coli str. K-12 substr. DH10B 6058852 YP_001730897.1 CDS yedF NC_010473.1 2098511 2098744 D hypothetical protein 2098511..2098744 Escherichia coli str. K-12 substr. DH10B 6058854 YP_001730898.1 CDS yedK NC_010473.1 2098853 2099521 D hypothetical protein 2098853..2099521 Escherichia coli str. K-12 substr. DH10B 6058865 YP_001730899.1 CDS yedL NC_010473.1 2099632 2100111 D acyltransferase 2099632..2100111 Escherichia coli str. K-12 substr. DH10B 6058869 YP_001730900.1 CDS yedM NC_010473.1 2101033 2101383 R hypothetical protein complement(2101033..2101383) Escherichia coli str. K-12 substr. DH10B 6058897 YP_001730901.1 CDS fliE NC_010473.1 2101732 2102046 R forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE complement(2101732..2102046) Escherichia coli str. K-12 substr. DH10B 6059128 YP_001730902.1 CDS fliF NC_010473.1 2102261 2103919 D the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 2102261..2103919 Escherichia coli str. K-12 substr. DH10B 6058900 YP_001730903.1 CDS fliG NC_010473.1 2103912 2104907 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 2103912..2104907 Escherichia coli str. K-12 substr. DH10B 6058907 YP_001730904.1 CDS fliH NC_010473.1 2104900 2105586 D binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 2104900..2105586 Escherichia coli str. K-12 substr. DH10B 6058917 YP_001730905.1 CDS fliI NC_010473.1 2105586 2106959 D involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 2105586..2106959 Escherichia coli str. K-12 substr. DH10B 6058927 YP_001730906.1 CDS fliJ NC_010473.1 2106978 2107421 D rod/hook and filament chaperone; flagellar biosynthesis chaperone 2106978..2107421 Escherichia coli str. K-12 substr. DH10B 6058942 YP_001730907.1 CDS fliK NC_010473.1 2107418 2108545 D flagellar hook-length control protein 2107418..2108545 Escherichia coli str. K-12 substr. DH10B 6058944 YP_001730908.1 CDS fliL NC_010473.1 2108650 2109114 D interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 2108650..2109114 Escherichia coli str. K-12 substr. DH10B 6058951 YP_001730909.1 CDS fliM NC_010473.1 2109119 2110123 D with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 2109119..2110123 Escherichia coli str. K-12 substr. DH10B 6058954 YP_001730910.1 CDS fliN NC_010473.1 2110120 2110533 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 2110120..2110533 Escherichia coli str. K-12 substr. DH10B 6058975 YP_001730911.1 CDS fliO NC_010473.1 2110536 2110901 D with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus; flagellar biosynthesis protein FliO 2110536..2110901 Escherichia coli str. K-12 substr. DH10B 6058986 YP_001730912.1 CDS fliP NC_010473.1 2110901 2111638 D FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 2110901..2111638 Escherichia coli str. K-12 substr. DH10B 6059001 YP_001730913.1 CDS fliQ NC_010473.1 2111648 2111917 D with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 2111648..2111917 Escherichia coli str. K-12 substr. DH10B 6059019 YP_001730914.1 CDS fliR NC_010473.1 2111925 2112710 D FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 2111925..2112710 Escherichia coli str. K-12 substr. DH10B 6059021 YP_001730915.1 CDS rcsA NC_010473.1 2113000 2113623 D DNA-binding transcriptional activator, co-regulator with RcsB 2113000..2113623 Escherichia coli str. K-12 substr. DH10B 6059025 YP_001730916.1 CDS dsrB NC_010473.1 2113667 2113855 R hypothetical protein complement(2113667..2113855) Escherichia coli str. K-12 substr. DH10B 6059033 YP_001730917.1 CDS yodD NC_010473.1 2114018 2114245 D hypothetical protein 2114018..2114245 Escherichia coli str. K-12 substr. DH10B 6059038 YP_001730918.1 CDS yedP NC_010473.1 2114543 2115358 D catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 2114543..2115358 Escherichia coli str. K-12 substr. DH10B 6058946 YP_001730919.1 CDS yedQ NC_010473.1 2115355 2117049 R diguanylate cyclase complement(2115355..2117049) Escherichia coli str. K-12 substr. DH10B 6059077 YP_001730920.1 CDS yodC NC_010473.1 2117220 2117402 R hypothetical protein complement(2117220..2117402) Escherichia coli str. K-12 substr. DH10B 6059079 YP_001730921.1 CDS yedI NC_010473.1 2117481 2118398 R hypothetical protein complement(2117481..2118398) Escherichia coli str. K-12 substr. DH10B 6059082 YP_001730922.1 CDS yedA NC_010473.1 2118571 2119491 D hypothetical protein 2118571..2119491 Escherichia coli str. K-12 substr. DH10B 6059092 YP_001730923.1 CDS vsr NC_010473.1 2119480 2119950 R DNA mismatch endonuclease of very short patch repair complement(2119480..2119950) Escherichia coli str. K-12 substr. DH10B 6059095 YP_001730924.1 CDS dcm NC_010473.1 2119931 2121349 R DNA cytosine methylase complement(2119931..2121349) Escherichia coli str. K-12 substr. DH10B 6059099 YP_001730925.1 CDS yedJ NC_010473.1 2121416 2122111 R hypothetical protein complement(2121416..2122111) Escherichia coli str. K-12 substr. DH10B 6059110 YP_001730926.1 CDS yedR NC_010473.1 2122151 2122516 R inner membrane protein complement(2122151..2122516) Escherichia coli str. K-12 substr. DH10B 6059113 YP_001730927.1 CDS hchA NC_010473.1 2124867 2125718 D Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 2124867..2125718 Escherichia coli str. K-12 substr. DH10B 6059114 YP_001730928.1 CDS yedV NC_010473.1 2125826 2127184 R sensory kinase in two-component regulatory system with YedW complement(2125826..2127184) Escherichia coli str. K-12 substr. DH10B 6059118 YP_001730929.1 CDS yedW NC_010473.1 2127184 2127855 R induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced; transcriptional regulatory protein YedW complement(2127184..2127855) Escherichia coli str. K-12 substr. DH10B 6059126 YP_001730930.1 CDS yedX NC_010473.1 2127988 2128401 D hypothetical protein 2127988..2128401 Escherichia coli str. K-12 substr. DH10B 6059127 YP_001730931.1 CDS yedZ NC_010473.1 2129515 2130150 D in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; putative sulfite oxidase subunit YedZ 2129515..2130150 Escherichia coli str. K-12 substr. DH10B 6059161 YP_001730932.1 CDS yodA NC_010473.1 2130407 2131057 D hypothetical protein 2130407..2131057 Escherichia coli str. K-12 substr. DH10B 6059163 YP_001730933.1 CDS yodB NC_010473.1 2131400 2131930 D cytochrome 2131400..2131930 Escherichia coli str. K-12 substr. DH10B 6059164 YP_001730934.1 CDS yeeI NC_010473.1 2132683 2133480 D hypothetical protein 2132683..2133480 Escherichia coli str. K-12 substr. DH10B 6059210 YP_001730935.1 CDS yeeJ NC_010473.1 2133943 2141046 D adhesin 2133943..2141046 Escherichia coli str. K-12 substr. DH10B 6058719 YP_001730936.1 CDS shiA NC_010473.1 2142675 2143991 D shikimate transporter 2142675..2143991 Escherichia coli str. K-12 substr. DH10B 6059175 YP_001730937.1 CDS amn NC_010473.1 2144093 2145547 D Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 2144093..2145547 Escherichia coli str. K-12 substr. DH10B 6059191 YP_001730938.1 CDS yeeN NC_010473.1 2145890 2146606 D hypothetical protein 2145890..2146606 Escherichia coli str. K-12 substr. DH10B 6059209 YP_001730939.1 CDS yeeO NC_010473.1 2147235 2148878 R hypothetical protein complement(2147235..2148878) Escherichia coli str. K-12 substr. DH10B 6060015 YP_001730940.1 CDS cbl NC_010473.1 2148996 2149946 R LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl complement(2148996..2149946) Escherichia coli str. K-12 substr. DH10B 6062043 YP_001730941.1 CDS nac NC_010473.1 2150048 2150965 R Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator complement(2150048..2150965) Escherichia coli str. K-12 substr. DH10B 6059224 YP_001730942.1 CDS erfK NC_010473.1 2151423 2152355 R hypothetical protein complement(2151423..2152355) Escherichia coli str. K-12 substr. DH10B 6062315 YP_001730943.1 CDS cobT NC_010473.1 2152420 2153499 R catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase complement(2152420..2153499) Escherichia coli str. K-12 substr. DH10B 6059234 YP_001730944.1 CDS cobS NC_010473.1 2153511 2154254 R catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase complement(2153511..2154254) Escherichia coli str. K-12 substr. DH10B 6059236 YP_001730945.1 CDS cobU NC_010473.1 2154251 2154796 R catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase complement(2154251..2154796) Escherichia coli str. K-12 substr. DH10B 6059245 YP_001730946.1 CDS insH-6 NC_010473.1 2155337 2156353 R CP4-44 prophage; IS5 transposase and trans-activator complement(2155337..2156353) Escherichia coli str. K-12 substr. DH10B 6059260 YP_001730947.1 CDS insD-3 NC_010473.1 2157984 2158889 R IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD complement(2157984..2158889) Escherichia coli str. K-12 substr. DH10B 6059268 YP_001730948.1 CDS insC-3 NC_010473.1 2158847 2159257 R IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein complement(2158847..2159257) Escherichia coli str. K-12 substr. DH10B 6059271 YP_001730949.1 CDS flu NC_010473.1 2160571 2163690 D CP4-44 prophage; antigen 43 (Ag43) phase-variable biofilm formation autotransporter 2160571..2163690 Escherichia coli str. K-12 substr. DH10B 6062384 YP_001730950.1 CDS yeeR NC_010473.1 2163811 2165343 D CP4-44 prophage; membrane protein 2163811..2165343 Escherichia coli str. K-12 substr. DH10B 6059288 YP_001730951.1 CDS yeeS NC_010473.1 2165340 2165786 D CP4-44 prophage; DNA repair protein 2165340..2165786 Escherichia coli str. K-12 substr. DH10B 6059296 YP_001730952.1 CDS yeeT NC_010473.1 2165849 2166070 D CP4-44 prophage; protein 2165849..2166070 Escherichia coli str. K-12 substr. DH10B 6059302 YP_001730953.1 CDS yeeU NC_010473.1 2166144 2166512 D CP4-44 prophage; antitoxin of the YeeV-YeeU toxin-antitoxin system 2166144..2166512 Escherichia coli str. K-12 substr. DH10B 6059303 YP_001730954.1 CDS yeeV NC_010473.1 2166601 2166975 D CP4-44 prophage; toxin of the YeeV-YeeU toxin-antitoxin system 2166601..2166975 Escherichia coli str. K-12 substr. DH10B 6059307 YP_001730955.1 CDS yeeW NC_010473.1 2166972 2167166 D CP4-44 prophage; protein 2166972..2167166 Escherichia coli str. K-12 substr. DH10B 6059311 YP_001730956.1 CDS yoeF NC_010473.1 2167607 2167963 D hypothetical protein 2167607..2167963 Escherichia coli str. K-12 substr. DH10B 6059323 YP_001730957.1 CDS yeeX NC_010473.1 2168064 2168459 R hypothetical protein complement(2168064..2168459) Escherichia coli str. K-12 substr. DH10B 6059332 YP_001730958.1 CDS yeeA NC_010473.1 2168565 2169623 R inner membrane protein complement(2168565..2169623) Escherichia coli str. K-12 substr. DH10B 6059340 YP_001730959.1 CDS sbmC NC_010473.1 2169821 2170294 R DNA gyrase inhibitor complement(2169821..2170294) Escherichia coli str. K-12 substr. DH10B 6059347 YP_001730960.1 CDS dacD NC_010473.1 2170413 2171579 R removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase complement(2170413..2171579) Escherichia coli str. K-12 substr. DH10B 6059350 YP_001730961.1 CDS sbcB NC_010473.1 2171788 2173215 D Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 2171788..2173215 Escherichia coli str. K-12 substr. DH10B 6059358 YP_001730962.1 CDS yeeD NC_010473.1 2173258 2173485 R hypothetical protein complement(2173258..2173485) Escherichia coli str. K-12 substr. DH10B 6059360 YP_001730963.1 CDS yeeE NC_010473.1 2173499 2174557 R inner membrane protein complement(2173499..2174557) Escherichia coli str. K-12 substr. DH10B 6059362 YP_001730964.1 CDS yeeF NC_010473.1 2174736 2176094 R amino-acid transporter complement(2174736..2176094) Escherichia coli str. K-12 substr. DH10B 6059363 YP_001730965.1 CDS yeeY NC_010473.1 2176361 2177290 R DNA-binding transcriptional regulator complement(2176361..2177290) Escherichia coli str. K-12 substr. DH10B 6059364 YP_001730966.1 CDS yeeZ NC_010473.1 2177336 2178160 R epimerase complement(2177336..2178160) Escherichia coli str. K-12 substr. DH10B 6059366 YP_001730967.1 CDS yoeB NC_010473.1 2178243 2178497 R toxin of the YoeB-YefM toxin-antitoxin system complement(2178243..2178497) Escherichia coli str. K-12 substr. DH10B 6059368 YP_001730968.1 CDS yefM NC_010473.1 2178494 2178745 R Antitoxin that counteracts the effect of the YoeB toxin; antitoxin YefM complement(2178494..2178745) Escherichia coli str. K-12 substr. DH10B 6059381 YP_001730970.1 CDS hisG NC_010473.1 2179224 2180123 D long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2179224..2180123 Escherichia coli str. K-12 substr. DH10B 6059384 YP_001730971.1 CDS hisD NC_010473.1 2180129 2181433 D catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2180129..2181433 Escherichia coli str. K-12 substr. DH10B 6059387 YP_001730972.1 CDS hisC NC_010473.1 2181430 2182500 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2181430..2182500 Escherichia coli str. K-12 substr. DH10B 6059393 YP_001730973.1 CDS hisB NC_010473.1 2182500 2183567 D catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2182500..2183567 Escherichia coli str. K-12 substr. DH10B 6059394 YP_001730974.1 CDS hisH NC_010473.1 2183567 2184157 D with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2183567..2184157 Escherichia coli str. K-12 substr. DH10B 6059418 YP_001730975.1 CDS hisA NC_010473.1 2184157 2184894 D catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2184157..2184894 Escherichia coli str. K-12 substr. DH10B 6059421 YP_001730976.1 CDS hisF NC_010473.1 2184876 2185652 D catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2184876..2185652 Escherichia coli str. K-12 substr. DH10B 6059433 YP_001730977.1 CDS hisI NC_010473.1 2185646 2186257 D catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 2185646..2186257 Escherichia coli str. K-12 substr. DH10B 6059450 YP_001730978.1 CDS cld NC_010473.1 2186353 2187333 R regulator of length of O-antigen component of lipopolysaccharide chains complement(2186353..2187333) Escherichia coli str. K-12 substr. DH10B 6059452 YP_001730979.1 CDS ugd NC_010473.1 2187479 2188645 R UDP-glucose 6-dehydrogenase complement(2187479..2188645) Escherichia coli str. K-12 substr. DH10B 6059458 YP_001730980.1 CDS gnd NC_010473.1 2188894 2190300 R catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase complement(2188894..2190300) Escherichia coli str. K-12 substr. DH10B 6059459 YP_001730981.1 CDS insH-7 NC_010473.1 2190927 2191943 R IS5 transposase and trans-activator complement(2190927..2191943) Escherichia coli str. K-12 substr. DH10B 6059463 YP_001730982.1 CDS wbbK NC_010473.1 2192423 2193541 R lipopolysaccharide biosynthesis protein complement(2192423..2193541) Escherichia coli str. K-12 substr. DH10B 6059468 YP_001730983.1 CDS wbbJ NC_010473.1 2193526 2194116 R WbbJ; catalyzes the transfer of the O-acetyl moiety to the O antigen; part of the lipopolysaccharide biosynthetic pathway; putative lipopolysaccharide biosynthesis O-acetyl transferase WbbJ complement(2193526..2194116) Escherichia coli str. K-12 substr. DH10B 6059472 YP_001730984.1 CDS wbbI NC_010473.1 2194097 2195089 R hypothetical protein complement(2194097..2195089) Escherichia coli str. K-12 substr. DH10B 6059478 YP_001730985.1 CDS wbbH NC_010473.1 2195092 2196258 R O-antigen polymerase complement(2195092..2196258) Escherichia coli str. K-12 substr. DH10B 6059489 YP_001730986.1 CDS glf NC_010473.1 2196258 2197361 R UDP-galactopyranose mutase, FAD/NAD(P)-binding complement(2196258..2197361) Escherichia coli str. K-12 substr. DH10B 6059501 YP_001730987.1 CDS rfbX NC_010473.1 2197369 2198616 R polisoprenol-linked O-antigen transporter complement(2197369..2198616) Escherichia coli str. K-12 substr. DH10B 6059502 YP_001730988.1 CDS rfbC NC_010473.1 2198613 2199170 R dTDP-4-deoxyrhamnose-3,5-epimerase complement(2198613..2199170) Escherichia coli str. K-12 substr. DH10B 6059503 YP_001730989.1 CDS rfbA NC_010473.1 2199170 2200051 R glucose-1-phosphate thymidylyltransferase complement(2199170..2200051) Escherichia coli str. K-12 substr. DH10B 6059507 YP_001730990.1 CDS rfbD NC_010473.1 2200109 2201008 R with dTDP-4-dehydrorhamnose 3,5-epimerase forms a complex known as dTDP-L-rhamnose synthetase; catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose; dTDP-4-dehydrorhamnose reductase complement(2200109..2201008) Escherichia coli str. K-12 substr. DH10B 6059508 YP_001730991.1 CDS rfbB NC_010473.1 2201008 2202093 R NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose; dTDP-glucose-4,6-dehydratase complement(2201008..2202093) Escherichia coli str. K-12 substr. DH10B 6059518 YP_001730992.1 CDS galF NC_010473.1 2202466 2203359 R together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalF complement(2202466..2203359) Escherichia coli str. K-12 substr. DH10B 6059521 YP_001730993.1 CDS wcaM NC_010473.1 2203534 2204928 R WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; putative colanic acid biosynthesis protein complement(2203534..2204928) Escherichia coli str. K-12 substr. DH10B 6059522 YP_001730994.1 CDS wcaL NC_010473.1 2204939 2206159 R glycosyl transferase family protein complement(2204939..2206159) Escherichia coli str. K-12 substr. DH10B 6059525 YP_001730995.1 CDS wcaK NC_010473.1 2206156 2207436 R putative pyruvyl transferase complement(2206156..2207436) Escherichia coli str. K-12 substr. DH10B 6059528 YP_001730996.1 CDS wzxC NC_010473.1 2207712 2209190 R colanic acid exporter complement(2207712..2209190) Escherichia coli str. K-12 substr. DH10B 6059540 YP_001730997.1 CDS wcaJ NC_010473.1 2209192 2210586 R WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; putative UDP-glucose lipid carrier transferase complement(2209192..2210586) Escherichia coli str. K-12 substr. DH10B 6059544 YP_001730998.1 CDS cpsG NC_010473.1 2210641 2212011 R phosphomannomutase complement(2210641..2212011) Escherichia coli str. K-12 substr. DH10B 6059546 YP_001730999.1 CDS cpsB NC_010473.1 2212116 2213552 R mannose-1-phosphate guanyltransferase complement(2212116..2213552) Escherichia coli str. K-12 substr. DH10B 6059558 YP_001731000.1 CDS wcaI NC_010473.1 2213555 2214778 R putative glycosyl transferase complement(2213555..2214778) Escherichia coli str. K-12 substr. DH10B 6059563 YP_001731001.1 CDS nudD NC_010473.1 2214775 2215254 R GDP-mannose mannosyl hydrolase complement(2214775..2215254) Escherichia coli str. K-12 substr. DH10B 6059566 YP_001731002.1 CDS fcl NC_010473.1 2215257 2216222 R bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase and GDP-4-dehydro-6-L-deoxygalactose reductase complement(2215257..2216222) Escherichia coli str. K-12 substr. DH10B 6059576 YP_001731003.1 CDS gmd NC_010473.1 2216225 2217346 R GDP-D-mannose dehydratase complement(2216225..2217346) Escherichia coli str. K-12 substr. DH10B 6059580 YP_001731004.1 CDS wcaF NC_010473.1 2217372 2217920 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); putative colanic acid biosynthesis acetyltransferase WcaF complement(2217372..2217920) Escherichia coli str. K-12 substr. DH10B 6059586 YP_001731005.1 CDS wcaE NC_010473.1 2217936 2218682 R putative glycosyl transferase complement(2217936..2218682) Escherichia coli str. K-12 substr. DH10B 6059589 YP_001731006.1 CDS wcaD NC_010473.1 2218693 2219910 R essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; putative colanic acid biosynthesis protein complement(2218693..2219910) Escherichia coli str. K-12 substr. DH10B 6059591 YP_001731007.1 CDS wcaC NC_010473.1 2219885 2221102 R putative glycosyl transferase complement(2219885..2221102) Escherichia coli str. K-12 substr. DH10B 6059594 YP_001731008.1 CDS wcaB NC_010473.1 2221099 2221587 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; putative colanic acid biosynthesis acetyltransferase WcaB complement(2221099..2221587) Escherichia coli str. K-12 substr. DH10B 6059599 YP_001731009.1 CDS wcaA NC_010473.1 2221590 2222429 R putative glycosyl transferase complement(2221590..2222429) Escherichia coli str. K-12 substr. DH10B 6059614 YP_001731010.1 CDS wzc NC_010473.1 2222522 2224684 R Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase complement(2222522..2224684) Escherichia coli str. K-12 substr. DH10B 6059620 YP_001731011.1 CDS wzb NC_010473.1 2224687 2225130 R Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase complement(2224687..2225130) Escherichia coli str. K-12 substr. DH10B 6059622 YP_001731012.1 CDS wza NC_010473.1 2225136 2226275 R lipoprotein required for capsular polysaccharide translocation through the outer membrane complement(2225136..2226275) Escherichia coli str. K-12 substr. DH10B 6059631 YP_001731013.1 CDS yegH NC_010473.1 2226934 2228517 D fused membrane protein; membrane protein 2226934..2228517 Escherichia coli str. K-12 substr. DH10B 6059638 YP_001731014.1 CDS asmA NC_010473.1 2228791 2230644 R YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; putative assembly protein complement(2228791..2230644) Escherichia coli str. K-12 substr. DH10B 6059644 YP_001731015.1 CDS dcd NC_010473.1 2230666 2231247 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(2230666..2231247) Escherichia coli str. K-12 substr. DH10B 6059647 YP_001731016.1 CDS udk NC_010473.1 2231339 2231980 R functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase complement(2231339..2231980) Escherichia coli str. K-12 substr. DH10B 6059654 YP_001731017.1 CDS yegE NC_010473.1 2232298 2235615 D contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction; putative sensor protein 2232298..2235615 Escherichia coli str. K-12 substr. DH10B 6059656 YP_001731018.1 CDS alkA NC_010473.1 2235724 2236572 R inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyladenine DNA glycosylase complement(2235724..2236572) Escherichia coli str. K-12 substr. DH10B 6059665 YP_001731019.1 CDS yegD NC_010473.1 2236706 2238058 D putative chaperone 2236706..2238058 Escherichia coli str. K-12 substr. DH10B 6059680 YP_001731020.1 CDS yegI NC_010473.1 2238071 2240017 R hypothetical protein complement(2238071..2240017) Escherichia coli str. K-12 substr. DH10B 6059682 YP_001731021.1 CDS yegJ NC_010473.1 2240217 2240678 D hypothetical protein 2240217..2240678 Escherichia coli str. K-12 substr. DH10B 6059694 YP_001731022.1 CDS yegK NC_010473.1 2240743 2241504 R hypothetical protein complement(2240743..2241504) Escherichia coli str. K-12 substr. DH10B 6059710 YP_001731023.1 CDS yegL NC_010473.1 2241501 2242160 R hypothetical protein complement(2241501..2242160) Escherichia coli str. K-12 substr. DH10B 6059711 YP_001731024.1 CDS mdtA NC_010473.1 2243048 2244295 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2243048..2244295 Escherichia coli str. K-12 substr. DH10B 6060091 YP_001731025.1 CDS mdtB NC_010473.1 2244295 2247417 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2244295..2247417 Escherichia coli str. K-12 substr. DH10B 6059722 YP_001731026.1 CDS mdtC NC_010473.1 2247418 2250495 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2247418..2250495 Escherichia coli str. K-12 substr. DH10B 6059728 YP_001731027.1 CDS mdtD NC_010473.1 2250496 2251911 D multidrug efflux system protein MdtE 2250496..2251911 Escherichia coli str. K-12 substr. DH10B 6059734 YP_001731028.1 CDS baeS NC_010473.1 2251908 2253311 D signal transduction histidine-protein kinase BaeS 2251908..2253311 Escherichia coli str. K-12 substr. DH10B 6059735 YP_001731029.1 CDS baeR NC_010473.1 2253308 2254030 D response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2253308..2254030 Escherichia coli str. K-12 substr. DH10B 6059737 YP_001731030.1 CDS yegP NC_010473.1 2254221 2254553 D hypothetical protein 2254221..2254553 Escherichia coli str. K-12 substr. DH10B 6059738 YP_001731031.1 CDS yegQ NC_010473.1 2254700 2256061 D peptidase 2254700..2256061 Escherichia coli str. K-12 substr. DH10B 6059745 YP_001731032.1 CDS ogrK NC_010473.1 2256334 2256552 R in E. coli K-12 this is in prophage P2 remnant; DNA-binding transcriptional regulator complement(2256334..2256552) Escherichia coli str. K-12 substr. DH10B 6058567 YP_001731033.1 CDS yegR NC_010473.1 2257021 2257338 R hypothetical protein complement(2257021..2257338) Escherichia coli str. K-12 substr. DH10B 6059757 YP_001731034.1 CDS yegS NC_010473.1 2257744 2258643 D cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2257744..2258643 Escherichia coli str. K-12 substr. DH10B 6059769 YP_001731035.1 CDS insE-5 NC_010473.1 2259259 2259567 D IS3 element protein InsE 2259259..2259567 Escherichia coli str. K-12 substr. DH10B 6059781 YP_001731036.1 CDS insF-5 NC_010473.1 2259564 2260430 D IS3 element protein InsF 2259564..2260430 Escherichia coli str. K-12 substr. DH10B 6059801 YP_001731037.1 CDS gatD NC_010473.1 2260865 2261905 R Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate; galactitol-1-phosphate dehydrogenase complement(2260865..2261905) Escherichia coli str. K-12 substr. DH10B 6059804 YP_001731038.1 CDS gatC NC_010473.1 2261953 2263308 R PTS system galactitol-specific transporter subunit IIC complement(2261953..2263308) Escherichia coli str. K-12 substr. DH10B 6059807 YP_001731039.1 CDS gatB NC_010473.1 2263312 2263596 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIB complement(2263312..2263596) Escherichia coli str. K-12 substr. DH10B 6059810 YP_001731040.1 CDS gatA NC_010473.1 2263627 2264079 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system galactitol-specific transporter subunit IIA complement(2263627..2264079) Escherichia coli str. K-12 substr. DH10B 6059816 YP_001731041.1 CDS gatY NC_010473.1 2265380 2266234 R catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase complement(2265380..2266234) Escherichia coli str. K-12 substr. DH10B 6059825 YP_001731042.1 CDS fbaB NC_010473.1 2266542 2267594 R catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase complement(2266542..2267594) Escherichia coli str. K-12 substr. DH10B 6059826 YP_001731043.1 CDS yegT NC_010473.1 2267851 2269128 D nucleoside transporter 2267851..2269128 Escherichia coli str. K-12 substr. DH10B 6059833 YP_001731044.1 CDS yegU NC_010473.1 2269125 2270129 D hydrolase 2269125..2270129 Escherichia coli str. K-12 substr. DH10B 6059852 YP_001731045.1 CDS yegV NC_010473.1 2270126 2271091 D kinase 2270126..2271091 Escherichia coli str. K-12 substr. DH10B 6059853 YP_001731046.1 CDS yegW NC_010473.1 2271065 2271811 R DNA-binding transcriptional regulator complement(2271065..2271811) Escherichia coli str. K-12 substr. DH10B 6059860 YP_001731047.1 CDS yegX NC_010473.1 2271863 2272681 R hydrolase complement(2271863..2272681) Escherichia coli str. K-12 substr. DH10B 6058923 YP_001731048.1 CDS thiD NC_010473.1 2272746 2273546 R catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase complement(2272746..2273546) Escherichia coli str. K-12 substr. DH10B 6059863 YP_001731049.1 CDS thiM NC_010473.1 2273543 2274331 R catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase complement(2273543..2274331) Escherichia coli str. K-12 substr. DH10B 6059864 YP_001731050.1 CDS rcnR NC_010473.1 2274554 2274826 R transcriptional repressor of rcnA complement(2274554..2274826) Escherichia coli str. K-12 substr. DH10B 6059871 YP_001731051.1 CDS yohM NC_010473.1 2274947 2275771 D membrane protein conferring nickel and cobalt resistance; nickel/cobalt efflux protein RcnA 2274947..2275771 Escherichia coli str. K-12 substr. DH10B 6060390 YP_001731052.1 CDS yohN NC_010473.1 2275990 2276328 D hypothetical protein 2275990..2276328 Escherichia coli str. K-12 substr. DH10B 6059876 YP_001731053.1 CDS yehB NC_010473.1 2277460 2279940 R outer membrane protein complement(2277460..2279940) Escherichia coli str. K-12 substr. DH10B 6058766 YP_001731054.1 CDS yehC NC_010473.1 2279956 2280675 R periplasmic pilin chaperone complement(2279956..2280675) Escherichia coli str. K-12 substr. DH10B 6059885 YP_001731055.1 CDS yehD NC_010473.1 2280710 2281252 R fimbrial-like adhesin protein complement(2280710..2281252) Escherichia coli str. K-12 substr. DH10B 6059887 YP_001731056.1 CDS yehE NC_010473.1 2281545 2281826 R hypothetical protein complement(2281545..2281826) Escherichia coli str. K-12 substr. DH10B 6059911 YP_001731057.1 CDS mrp NC_010473.1 2282089 2283198 R putative ATPase complement(2282089..2283198) Escherichia coli str. K-12 substr. DH10B 6059913 YP_001731058.1 CDS metG NC_010473.1 2283330 2285363 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2283330..2285363 Escherichia coli str. K-12 substr. DH10B 6059122 YP_001731059.1 CDS yehI NC_010473.1 2289309 2292941 D hypothetical protein 2289309..2292941 Escherichia coli str. K-12 substr. DH10B 6059101 YP_001731060.1 CDS yehK NC_010473.1 2293002 2293319 D hypothetical protein 2293002..2293319 Escherichia coli str. K-12 substr. DH10B 6059954 YP_001731061.1 CDS yehL NC_010473.1 2293626 2294714 D ABC transporter ATP-binding protein 2293626..2294714 Escherichia coli str. K-12 substr. DH10B 6058749 YP_001731062.1 CDS yehM NC_010473.1 2294725 2297004 D hypothetical protein 2294725..2297004 Escherichia coli str. K-12 substr. DH10B 6058750 YP_001731063.1 CDS yehP NC_010473.1 2296997 2298133 D hypothetical protein 2296997..2298133 Escherichia coli str. K-12 substr. DH10B 6058751 YP_001731064.1 CDS yehQ NC_010473.1 2298130 2299974 D hypothetical protein 2298130..2299974 Escherichia coli str. K-12 substr. DH10B 6058756 YP_001731065.1 CDS yehR NC_010473.1 2300255 2300716 D hypothetical protein 2300255..2300716 Escherichia coli str. K-12 substr. DH10B 6058757 YP_001731066.1 CDS yehS NC_010473.1 2300756 2301226 R hypothetical protein complement(2300756..2301226) Escherichia coli str. K-12 substr. DH10B 6058758 YP_001731067.1 CDS yehT NC_010473.1 2301273 2301992 R unknown function; when overproduced it confers drug-resistance; putative two-component response-regulatory protein YehT complement(2301273..2301992) Escherichia coli str. K-12 substr. DH10B 6058763 YP_001731068.1 CDS yehU NC_010473.1 2301989 2303674 R sensory kinase in two-component system with YehT complement(2301989..2303674) Escherichia coli str. K-12 substr. DH10B 6058769 YP_001731069.1 CDS mlrA NC_010473.1 2303896 2304627 D DNA-binding transcriptional regulator 2303896..2304627 Escherichia coli str. K-12 substr. DH10B 6058771 YP_001731070.1 CDS yohO NC_010473.1 2304687 2304794 D hypothetical protein 2304687..2304794 Escherichia coli str. K-12 substr. DH10B 6059956 YP_001731071.1 CDS yehW NC_010473.1 2304775 2305506 R ABC transporter membrane protein complement(2304775..2305506) Escherichia coli str. K-12 substr. DH10B 6059994 YP_001731072.1 CDS yehX NC_010473.1 2305511 2306437 R ABC transporter ATP-binding protein complement(2305511..2306437) Escherichia coli str. K-12 substr. DH10B 6060008 YP_001731073.1 CDS yehY NC_010473.1 2306430 2307587 R ABC transporter membrane protein complement(2306430..2307587) Escherichia coli str. K-12 substr. DH10B 6060014 YP_001731074.1 CDS yehZ NC_010473.1 2307594 2308511 R ABC transporter substrate-binding protein complement(2307594..2308511) Escherichia coli str. K-12 substr. DH10B 6060025 YP_001731075.1 CDS bglX NC_010473.1 2308722 2311019 R beta-D-glucoside glucohydrolase, periplasmic complement(2308722..2311019) Escherichia coli str. K-12 substr. DH10B 6060026 YP_001731076.1 CDS dld NC_010473.1 2311215 2312930 D component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2311215..2312930 Escherichia coli str. K-12 substr. DH10B 6060037 YP_001731077.1 CDS pbpG NC_010473.1 2312968 2313900 R specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase complement(2312968..2313900) Escherichia coli str. K-12 substr. DH10B 6060044 YP_001731078.1 CDS yohC NC_010473.1 2314074 2314661 R inner membrane protein complement(2314074..2314661) Escherichia coli str. K-12 substr. DH10B 6059074 YP_001731079.1 CDS yohD NC_010473.1 2314831 2315409 D inner membrane protein 2314831..2315409 Escherichia coli str. K-12 substr. DH10B 6060056 YP_001731080.1 CDS yohF NC_010473.1 2315539 2316300 R acetoin dehydrogenase complement(2315539..2316300) Escherichia coli str. K-12 substr. DH10B 6060073 YP_001731081.1 CDS yohG NC_010473.1 2316353 2317441 R may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance outer membrane protein MdtQ complement(2316353..2317441) Escherichia coli str. K-12 substr. DH10B 6060126 YP_001731082.1 CDS yohH NC_010473.1 2317579 2317716 R hypothetical protein complement(2317579..2317716) Escherichia coli str. K-12 substr. DH10B 6060136 YP_001731083.1 CDS dusC NC_010473.1 2318468 2319415 R tRNA-dihydrouridine synthase C complement(2318468..2319415) Escherichia coli str. K-12 substr. DH10B 6058700 YP_001731084.1 CDS yohJ NC_010473.1 2319654 2320052 D hypothetical protein 2319654..2320052 Escherichia coli str. K-12 substr. DH10B 6060157 YP_001731085.1 CDS yohK NC_010473.1 2320049 2320744 D hypothetical protein 2320049..2320744 Escherichia coli str. K-12 substr. DH10B 6058640 YP_001731086.1 CDS cdd NC_010473.1 2320874 2321758 D Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2320874..2321758 Escherichia coli str. K-12 substr. DH10B 6060167 YP_001731087.1 CDS sanA NC_010473.1 2321908 2322627 D hypothetical protein 2321908..2322627 Escherichia coli str. K-12 substr. DH10B 6060176 YP_001731088.1 CDS yeiS NC_010473.1 2322630 2322869 D inner membrane protein 2322630..2322869 Escherichia coli str. K-12 substr. DH10B 6060204 YP_001731089.1 CDS yeiT NC_010473.1 2323063 2324301 D function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; putative oxidoreductase 2323063..2324301 Escherichia coli str. K-12 substr. DH10B 6060223 YP_001731090.1 CDS yeiA NC_010473.1 2324295 2325530 D catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2324295..2325530 Escherichia coli str. K-12 substr. DH10B 6060230 YP_001731091.1 CDS mglC NC_010473.1 2325773 2326783 R ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein complement(2325773..2326783) Escherichia coli str. K-12 substr. DH10B 6060271 YP_001731092.1 CDS mglB NC_010473.1 2328361 2329359 R methyl-galactoside ABC transporter periplasmic substrate-binding protein complement(2328361..2329359) Escherichia coli str. K-12 substr. DH10B 6058678 YP_001731093.1 CDS galS NC_010473.1 2329639 2330679 R negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS complement(2329639..2330679) Escherichia coli str. K-12 substr. DH10B 6060290 YP_001731094.1 CDS yeiB NC_010473.1 2330821 2331978 R hypothetical protein complement(2330821..2331978) Escherichia coli str. K-12 substr. DH10B 6060309 YP_001731095.1 CDS folE NC_010473.1 2331995 2332663 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(2331995..2332663) Escherichia coli str. K-12 substr. DH10B 6060311 YP_001731096.1 CDS yeiG NC_010473.1 2332921 2333757 D esterase 2332921..2333757 Escherichia coli str. K-12 substr. DH10B 6058679 YP_001731097.1 CDS cirA NC_010473.1 2333789 2335780 R Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor complement(2333789..2335780) Escherichia coli str. K-12 substr. DH10B 6060317 YP_001731098.1 CDS lysP NC_010473.1 2336074 2337543 R lysine transporter complement(2336074..2337543) Escherichia coli str. K-12 substr. DH10B 6060332 YP_001731099.1 CDS yeiE NC_010473.1 2337748 2338629 R putative DNA-binding transcriptional regulator complement(2337748..2338629) Escherichia coli str. K-12 substr. DH10B 6060333 YP_001731100.1 CDS yeiH NC_010473.1 2338728 2339777 D inner membrane protein 2338728..2339777 Escherichia coli str. K-12 substr. DH10B 6060349 YP_001731101.1 CDS nfo NC_010473.1 2339851 2340708 D Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2339851..2340708 Escherichia coli str. K-12 substr. DH10B 6060359 YP_001731102.1 CDS yeiI NC_010473.1 2340711 2341799 D hypothetical protein 2340711..2341799 Escherichia coli str. K-12 substr. DH10B 6060378 YP_001731103.1 CDS yeiJ NC_010473.1 2341906 2343156 R nucleoside transporter complement(2341906..2343156) Escherichia coli str. K-12 substr. DH10B 6060386 YP_001731104.1 CDS rihB NC_010473.1 2343256 2344197 R Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 complement(2343256..2344197) Escherichia coli str. K-12 substr. DH10B 6060412 YP_001731105.1 CDS yeiL NC_010473.1 2344366 2345025 D activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 2344366..2345025 Escherichia coli str. K-12 substr. DH10B 6060415 YP_001731106.1 CDS yeiM NC_010473.1 2345096 2346346 R nucleoside transporter complement(2345096..2346346) Escherichia coli str. K-12 substr. DH10B 6060430 YP_001731107.1 CDS yeiN NC_010473.1 2346440 2347378 R hypothetical protein complement(2346440..2347378) Escherichia coli str. K-12 substr. DH10B 6060453 YP_001731108.1 CDS yeiC NC_010473.1 2347366 2348307 R hypothetical protein complement(2347366..2348307) Escherichia coli str. K-12 substr. DH10B 6060455 YP_001731109.1 CDS fruA NC_010473.1 2348730 2350421 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunit IIBC complement(2348730..2350421) Escherichia coli str. K-12 substr. DH10B 6060473 YP_001731110.1 CDS fruK NC_010473.1 2350438 2351376 R converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase complement(2350438..2351376) Escherichia coli str. K-12 substr. DH10B 6060477 YP_001731111.1 CDS setB NC_010473.1 2352873 2354054 D lactose/glucose efflux system 2352873..2354054 Escherichia coli str. K-12 substr. DH10B 6060520 YP_001731112.1 CDS yeiW NC_010473.1 2354051 2354305 R hypothetical protein complement(2354051..2354305) Escherichia coli str. K-12 substr. DH10B 6060521 YP_001731113.1 CDS yeiP NC_010473.1 2354460 2355032 D Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 2354460..2355032 Escherichia coli str. K-12 substr. DH10B 6060523 YP_001731114.1 CDS yeiQ NC_010473.1 2355255 2356721 D dehydrogenase, NAD-dependent 2355255..2356721 Escherichia coli str. K-12 substr. DH10B 6060525 YP_001731115.1 CDS yeiR NC_010473.1 2356839 2357825 D hypothetical protein 2356839..2357825 Escherichia coli str. K-12 substr. DH10B 6060541 YP_001731116.1 CDS yeiU NC_010473.1 2357864 2358577 D undecaprenyl pyrophosphate phosphatase 2357864..2358577 Escherichia coli str. K-12 substr. DH10B 6060585 YP_001731117.1 CDS spr NC_010473.1 2358989 2359555 D by similarity, Spr seems to have peptidase activity; involved in thermoresistance; putative outer membrane lipoprotein 2358989..2359555 Escherichia coli str. K-12 substr. DH10B 6060596 YP_001731118.1 CDS rtn NC_010473.1 2359736 2361292 D hypothetical protein 2359736..2361292 Escherichia coli str. K-12 substr. DH10B 6060610 YP_001731119.1 CDS yejA NC_010473.1 2361374 2363188 D oligopeptide ABC transporter periplasmic-binding protein 2361374..2363188 Escherichia coli str. K-12 substr. DH10B 6060613 YP_001731120.1 CDS yejB NC_010473.1 2363189 2364283 D oligopeptide ABC transporter membrane protein 2363189..2364283 Escherichia coli str. K-12 substr. DH10B 6060645 YP_001731121.1 CDS yejE NC_010473.1 2364283 2365308 D oligopeptide ABC transporter membrane protein 2364283..2365308 Escherichia coli str. K-12 substr. DH10B 6060655 YP_001731122.1 CDS yejF NC_010473.1 2365310 2366899 D fused oligopeptide transporter subunits of ABC superfamilly: ATP-binding components 2365310..2366899 Escherichia coli str. K-12 substr. DH10B 6060666 YP_001731123.1 CDS yejG NC_010473.1 2366903 2367247 R hypothetical protein complement(2366903..2367247) Escherichia coli str. K-12 substr. DH10B 6060669 YP_001731124.1 CDS bcr NC_010473.1 2367580 2368770 R Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein complement(2367580..2368770) Escherichia coli str. K-12 substr. DH10B 6060673 YP_001731125.1 CDS rsuA NC_010473.1 2368798 2369493 R catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A complement(2368798..2369493) Escherichia coli str. K-12 substr. DH10B 6060694 YP_001731126.1 CDS yejH NC_010473.1 2369642 2371402 D ATP-dependet helicase 2369642..2371402 Escherichia coli str. K-12 substr. DH10B 6060718 YP_001731127.1 CDS rplY NC_010473.1 2371527 2371811 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 2371527..2371811 Escherichia coli str. K-12 substr. DH10B 6060723 YP_001731128.1 CDS yejK NC_010473.1 2371950 2372957 R nucleoid-associated protein NdpA complement(2371950..2372957) Escherichia coli str. K-12 substr. DH10B 6060733 YP_001731129.1 CDS yejL NC_010473.1 2373139 2373366 D hypothetical protein 2373139..2373366 Escherichia coli str. K-12 substr. DH10B 6060740 YP_001731130.1 CDS yejM NC_010473.1 2373386 2375146 D hydrolase, inner membrane 2373386..2375146 Escherichia coli str. K-12 substr. DH10B 6060742 YP_001731131.1 CDS yejO NC_010473.1 2375400 2377910 R autotransporter outer membrane protein complement(2375400..2377910) Escherichia coli str. K-12 substr. DH10B 6058422 YP_001731132.1 CDS insH-8 NC_010473.1 2378075 2379091 R IS5 transposase and trans-activator complement(2378075..2379091) Escherichia coli str. K-12 substr. DH10B 6060752 YP_001731133.1 CDS narP NC_010473.1 2379510 2380157 D nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 2379510..2380157 Escherichia coli str. K-12 substr. DH10B 6060767 YP_001731134.1 CDS ccmH NC_010473.1 2380368 2381420 R heme lyase, CcmH subunit complement(2380368..2381420) Escherichia coli str. K-12 substr. DH10B 6060778 YP_001731135.1 CDS ccmG NC_010473.1 2381417 2381974 R periplasmic thioredoxin of cytochrome c-type biogenesis complement(2381417..2381974) Escherichia coli str. K-12 substr. DH10B 6060152 YP_001731136.1 CDS ccmF NC_010473.1 2381971 2383914 R heme lyase, CcmF subunit complement(2381971..2383914) Escherichia coli str. K-12 substr. DH10B 6060486 YP_001731137.1 CDS ccmE NC_010473.1 2383911 2384390 R CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE complement(2383911..2384390) Escherichia coli str. K-12 substr. DH10B 6058616 YP_001731138.1 CDS ccmD NC_010473.1 2384387 2384596 R cytochrome c biogenesis protein complement(2384387..2384596) Escherichia coli str. K-12 substr. DH10B 6058673 YP_001731139.1 CDS ccmC NC_010473.1 2384593 2385330 R heme ABC transporter membrane protein complement(2384593..2385330) Escherichia coli str. K-12 substr. DH10B 6058723 YP_001731140.1 CDS ccmB NC_010473.1 2385372 2386034 R heme ABC transporter membrane protein complement(2385372..2386034) Escherichia coli str. K-12 substr. DH10B 6058859 YP_001731141.1 CDS ccmA NC_010473.1 2386031 2386654 R ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA complement(2386031..2386654) Escherichia coli str. K-12 substr. DH10B 6059046 YP_001731142.1 CDS napC NC_010473.1 2386667 2387269 R with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC complement(2386667..2387269) Escherichia coli str. K-12 substr. DH10B 6059094 YP_001731143.1 CDS napB NC_010473.1 2387279 2387728 R small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit complement(2387279..2387728) Escherichia coli str. K-12 substr. DH10B 6059474 YP_001731144.1 CDS napH NC_010473.1 2387725 2388588 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component complement(2387725..2388588) Escherichia coli str. K-12 substr. DH10B 6059828 YP_001731145.1 CDS napG NC_010473.1 2388575 2389270 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component complement(2388575..2389270) Escherichia coli str. K-12 substr. DH10B 6060067 YP_001731146.1 CDS napA NC_010473.1 2389277 2391763 R periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit complement(2389277..2391763) Escherichia coli str. K-12 substr. DH10B 6060165 YP_001731147.1 CDS napD NC_010473.1 2391760 2392023 R assembly protein for periplasmic nitrate reductase complement(2391760..2392023) Escherichia coli str. K-12 substr. DH10B 6058819 YP_001731148.1 CDS napF NC_010473.1 2392013 2392507 R Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA.; ferredoxin-type protein complement(2392013..2392507) Escherichia coli str. K-12 substr. DH10B 6058807 YP_001731149.1 CDS eco NC_010473.1 2392915 2393403 D serine protease inhibitor, inhibits trypsin and other proteases; ecotin 2392915..2393403 Escherichia coli str. K-12 substr. DH10B 6059505 YP_001731150.1 CDS mqo NC_010473.1 2394118 2395764 R malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase complement(2394118..2395764) Escherichia coli str. K-12 substr. DH10B 6059847 YP_001731151.1 CDS yojI NC_010473.1 2395982 2397625 R efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane protein/ATP-binding component complement(2395982..2397625) Escherichia coli str. K-12 substr. DH10B 6058824 YP_001731152.1 CDS alkB NC_010473.1 2397701 2398351 R oxidative demethylase of N1-methyladenine or N3-methylcytosine DNA lesions complement(2397701..2398351) Escherichia coli str. K-12 substr. DH10B 6059097 YP_001731153.1 CDS ada NC_010473.1 2398351 2399415 R fused DNA-binding transcriptional dual regulator; O6-methylguanine-DNA methyltransferase complement(2398351..2399415) Escherichia coli str. K-12 substr. DH10B 6059404 YP_001731154.1 CDS yojL NC_010473.1 2399489 2400544 R catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE complement(2399489..2400544) Escherichia coli str. K-12 substr. DH10B 6059590 YP_001731155.1 CDS ompC NC_010473.1 2400656 2401759 R allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C complement(2400656..2401759) Escherichia coli str. K-12 substr. DH10B 6059669 YP_001731156.1 CDS rcsD NC_010473.1 2402498 2405170 D phosphotransfer intermediate protein in two-component regulatory system with RcsBC 2402498..2405170 Escherichia coli str. K-12 substr. DH10B 6058542 YP_001731157.1 CDS rcsB NC_010473.1 2405187 2405837 D two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 2405187..2405837 Escherichia coli str. K-12 substr. DH10B 6059899 YP_001731158.1 CDS rcsC NC_010473.1 2406037 2408886 R hybrid sensory kinase in two-component regulatory system with RcsB and YojN complement(2406037..2408886) Escherichia coli str. K-12 substr. DH10B 6059883 YP_001731159.1 CDS atoS NC_010473.1 2409053 2410879 D with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; sensory histidine kinase AtoS 2409053..2410879 Escherichia coli str. K-12 substr. DH10B 6059829 YP_001731160.1 CDS atoC NC_010473.1 2410876 2412261 D with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; acetoacetate metabolism regulatory protein AtoC 2410876..2412261 Escherichia coli str. K-12 substr. DH10B 6059881 YP_001731161.1 CDS atoD NC_010473.1 2412457 2413119 D acetyl-CoA:acetoacetyl-CoA transferase subunit alpha 2412457..2413119 Escherichia coli str. K-12 substr. DH10B 6059872 YP_001731162.1 CDS atoA NC_010473.1 2413119 2413769 D acetyl-CoA:acetoacetyl-CoA transferase, beta subunit 2413119..2413769 Escherichia coli str. K-12 substr. DH10B 6059895 YP_001731163.1 CDS atoE NC_010473.1 2413766 2415088 D short chain fatty acid transporter 2413766..2415088 Escherichia coli str. K-12 substr. DH10B 6059890 YP_001731164.1 CDS atoB NC_010473.1 2415119 2416303 D acetyl-CoA acetyltransferase 2415119..2416303 Escherichia coli str. K-12 substr. DH10B 6062408 YP_001731165.1 CDS yfaP NC_010473.1 2416377 2417153 R hypothetical protein complement(2416377..2417153) Escherichia coli str. K-12 substr. DH10B 6060178 YP_001731166.1 CDS yfaQ NC_010473.1 2417158 2418807 R hypothetical protein complement(2417158..2418807) Escherichia coli str. K-12 substr. DH10B 6058084 YP_001731167.1 CDS yfaT NC_010473.1 2423346 2423969 R hypothetical protein complement(2423346..2423969) Escherichia coli str. K-12 substr. DH10B 6058113 YP_001731168.1 CDS yfaA NC_010473.1 2423966 2425654 R hypothetical protein complement(2423966..2425654) Escherichia coli str. K-12 substr. DH10B 6058120 YP_001731169.1 CDS gyrA NC_010473.1 2425803 2428430 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A complement(2425803..2428430) Escherichia coli str. K-12 substr. DH10B 6058121 YP_001731170.1 CDS ubiG NC_010473.1 2428577 2429299 D Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 2428577..2429299 Escherichia coli str. K-12 substr. DH10B 6058142 YP_001731171.1 CDS yfaL NC_010473.1 2429427 2433179 R adhesin complement(2429427..2433179) Escherichia coli str. K-12 substr. DH10B 6058150 YP_001731172.1 CDS nrdA NC_010473.1 2433875 2436160 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2433875..2436160 Escherichia coli str. K-12 substr. DH10B 6058156 YP_001731173.1 CDS nrdB NC_010473.1 2436394 2437524 D B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 2436394..2437524 Escherichia coli str. K-12 substr. DH10B 6058191 YP_001731174.1 CDS yfaE NC_010473.1 2437524 2437778 D plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 2437524..2437778 Escherichia coli str. K-12 substr. DH10B 6058192 YP_001731175.1 CDS inaA NC_010473.1 2437832 2438482 R hypothetical protein complement(2437832..2438482) Escherichia coli str. K-12 substr. DH10B 6058230 YP_001731176.1 CDS yfaH NC_010473.1 2438697 2438903 D hypothetical protein 2438697..2438903 Escherichia coli str. K-12 substr. DH10B 6058234 YP_001731177.1 CDS glpQ NC_010473.1 2438945 2440021 R hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase complement(2438945..2440021) Escherichia coli str. K-12 substr. DH10B 6058255 YP_001731178.1 CDS glpT NC_010473.1 2440026 2441384 R catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter complement(2440026..2441384) Escherichia coli str. K-12 substr. DH10B 6058297 YP_001731179.1 CDS glpA NC_010473.1 2441657 2443285 D anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 2441657..2443285 Escherichia coli str. K-12 substr. DH10B 6058301 YP_001731180.1 CDS glpB NC_010473.1 2443275 2444534 D sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 2443275..2444534 Escherichia coli str. K-12 substr. DH10B 6058319 YP_001731181.1 CDS glpC NC_010473.1 2444531 2445721 D anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 2444531..2445721 Escherichia coli str. K-12 substr. DH10B 6058330 YP_001731182.1 CDS yfaD NC_010473.1 2445914 2446813 D hypothetical protein 2445914..2446813 Escherichia coli str. K-12 substr. DH10B 6058346 YP_001731183.1 CDS yfaU NC_010473.1 2447052 2447855 R putative aldolase complement(2447052..2447855) Escherichia coli str. K-12 substr. DH10B 6058381 YP_001731184.1 CDS yfaV NC_010473.1 2447873 2449162 R transporter complement(2447873..2449162) Escherichia coli str. K-12 substr. DH10B 6058382 YP_001731185.1 CDS yfaW NC_010473.1 2449219 2450436 R enolase complement(2449219..2450436) Escherichia coli str. K-12 substr. DH10B 6058390 YP_001731186.1 CDS yfaX NC_010473.1 2450439 2451221 R DNA-binding transcriptional regulator complement(2450439..2451221) Escherichia coli str. K-12 substr. DH10B 6058397 YP_001731187.1 CDS yfaY NC_010473.1 2451441 2452643 R competence damage-inducible protein A complement(2451441..2452643) Escherichia coli str. K-12 substr. DH10B 6058455 YP_001731188.1 CDS yfaZ NC_010473.1 2452743 2453285 R outer membrane porin protein complement(2452743..2453285) Escherichia coli str. K-12 substr. DH10B 6058476 YP_001731189.1 CDS yfaO NC_010473.1 2453564 2453989 D NUDIX hydrolase 2453564..2453989 Escherichia coli str. K-12 substr. DH10B 6059295 YP_001731190.1 CDS ais NC_010473.1 2454028 2454630 R hypothetical protein complement(2454028..2454630) Escherichia coli str. K-12 substr. DH10B 6058500 YP_001731191.1 CDS arnB NC_010473.1 2454938 2456077 D catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 2454938..2456077 Escherichia coli str. K-12 substr. DH10B 6058503 YP_001731192.1 CDS arnC NC_010473.1 2456081 2457049 D catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase 2456081..2457049 Escherichia coli str. K-12 substr. DH10B 6058534 YP_001731193.1 CDS arnA NC_010473.1 2457049 2459031 D Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 2457049..2459031 Escherichia coli str. K-12 substr. DH10B 6058544 YP_001731194.1 CDS yfbH NC_010473.1 2459028 2459918 D hypothetical protein 2459028..2459918 Escherichia coli str. K-12 substr. DH10B 6058560 YP_001731195.1 CDS arnT NC_010473.1 2459918 2461570 D catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 2459918..2461570 Escherichia coli str. K-12 substr. DH10B 6058563 YP_001731196.1 CDS yfbW NC_010473.1 2461567 2461902 D hypothetical protein 2461567..2461902 Escherichia coli str. K-12 substr. DH10B 6058580 YP_001731197.1 CDS yfbJ NC_010473.1 2461902 2462288 D hypothetical protein 2461902..2462288 Escherichia coli str. K-12 substr. DH10B 6058589 YP_001731198.1 CDS pmrD NC_010473.1 2462282 2462548 R polymyxin resistance protein B complement(2462282..2462548) Escherichia coli str. K-12 substr. DH10B 6058599 YP_001731199.1 CDS menE NC_010473.1 2462658 2464013 R O-succinylbenzoic acid--CoA ligase complement(2462658..2464013) Escherichia coli str. K-12 substr. DH10B 6058607 YP_001731200.1 CDS menC NC_010473.1 2464010 2464972 R catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase complement(2464010..2464972) Escherichia coli str. K-12 substr. DH10B 6058613 YP_001731201.1 CDS menB NC_010473.1 2464972 2465829 R catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase complement(2464972..2465829) Escherichia coli str. K-12 substr. DH10B 6058627 YP_001731202.1 CDS yfbB NC_010473.1 2465844 2466602 R catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB complement(2465844..2466602) Escherichia coli str. K-12 substr. DH10B 6058643 YP_001731203.1 CDS menD NC_010473.1 2466599 2468269 R SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase complement(2466599..2468269) Escherichia coli str. K-12 substr. DH10B 6058661 YP_001731204.1 CDS menF NC_010473.1 2468358 2469653 R isochorismate synthase 2 complement(2468358..2469653) Escherichia coli str. K-12 substr. DH10B 6058685 YP_001731205.1 CDS elaB NC_010473.1 2469732 2470037 R hypothetical protein complement(2469732..2470037) Escherichia coli str. K-12 substr. DH10B 6058687 YP_001731206.1 CDS elaA NC_010473.1 2470092 2470553 R hypothetical protein complement(2470092..2470553) Escherichia coli str. K-12 substr. DH10B 6058688 YP_001731207.1 CDS elaD NC_010473.1 2472500 2473711 D ElaD; specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins; SseL in Salmonella is required for macrophage killing and virulence, and it is secreted by the salmonella pathogenicity island 2 type III secretion system; deubiquitinase 2472500..2473711 Escherichia coli str. K-12 substr. DH10B 6058695 YP_001731208.1 CDS yfbL NC_010473.1 2475647 2476618 D peptidase 2475647..2476618 Escherichia coli str. K-12 substr. DH10B 6058715 YP_001731209.1 CDS yfbM NC_010473.1 2476721 2477224 D hypothetical protein 2476721..2477224 Escherichia coli str. K-12 substr. DH10B 6058716 YP_001731210.1 CDS yfbN NC_010473.1 2477497 2478213 R hypothetical protein complement(2477497..2478213) Escherichia coli str. K-12 substr. DH10B 6058746 YP_001731211.1 CDS yfbO NC_010473.1 2478368 2478844 D hypothetical protein 2478368..2478844 Escherichia coli str. K-12 substr. DH10B 6058752 YP_001731212.1 CDS yfbP NC_010473.1 2478900 2479751 D hypothetical protein 2478900..2479751 Escherichia coli str. K-12 substr. DH10B 6058755 YP_001731213.1 CDS nuoN NC_010473.1 2479835 2481112 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N complement(2479835..2481112) Escherichia coli str. K-12 substr. DH10B 6058782 YP_001731214.1 CDS nuoM NC_010473.1 2481299 2482828 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M complement(2481299..2482828) Escherichia coli str. K-12 substr. DH10B 6058794 YP_001731215.1 CDS nuoL NC_010473.1 2482992 2484833 R Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L complement(2482992..2484833) Escherichia coli str. K-12 substr. DH10B 6058832 YP_001731216.1 CDS nuoK NC_010473.1 2484830 2485132 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K complement(2484830..2485132) Escherichia coli str. K-12 substr. DH10B 6058833 YP_001731217.1 CDS nuoJ NC_010473.1 2485129 2485683 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J complement(2485129..2485683) Escherichia coli str. K-12 substr. DH10B 6058844 YP_001731218.1 CDS nuoI NC_010473.1 2485695 2486237 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I complement(2485695..2486237) Escherichia coli str. K-12 substr. DH10B 6058845 YP_001731219.1 CDS nuoH NC_010473.1 2486252 2487229 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H complement(2486252..2487229) Escherichia coli str. K-12 substr. DH10B 6058868 YP_001731220.1 CDS nuoG NC_010473.1 2487226 2489958 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G complement(2487226..2489958) Escherichia coli str. K-12 substr. DH10B 6058872 YP_001731221.1 CDS nuoF NC_010473.1 2490005 2491342 R shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F complement(2490005..2491342) Escherichia coli str. K-12 substr. DH10B 6058884 YP_001731222.1 CDS nuoE NC_010473.1 2491339 2491839 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E complement(2491339..2491839) Escherichia coli str. K-12 substr. DH10B 6058886 YP_001731223.1 CDS nuoC NC_010473.1 2491842 2493644 R NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D complement(2491842..2493644) Escherichia coli str. K-12 substr. DH10B 6058903 YP_001731224.1 CDS nuoB NC_010473.1 2493738 2494400 R The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B complement(2493738..2494400) Escherichia coli str. K-12 substr. DH10B 6058908 YP_001731225.1 CDS nuoA NC_010473.1 2494416 2494859 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A complement(2494416..2494859) Escherichia coli str. K-12 substr. DH10B 6058909 YP_001731226.1 CDS lrhA NC_010473.1 2495490 2496428 R DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes complement(2495490..2496428) Escherichia coli str. K-12 substr. DH10B 6059316 YP_001731227.1 CDS yfbQ NC_010473.1 2497348 2498565 D broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 2497348..2498565 Escherichia coli str. K-12 substr. DH10B 6058932 YP_001731228.1 CDS yfbR NC_010473.1 2498649 2499248 D hypothetical protein 2498649..2499248 Escherichia coli str. K-12 substr. DH10B 6058934 YP_001731229.1 CDS yfbT NC_010473.1 2501226 2501876 R putative phosphatase complement(2501226..2501876) Escherichia coli str. K-12 substr. DH10B 6058939 YP_001731230.1 CDS yfbU NC_010473.1 2501887 2502381 R hypothetical protein complement(2501887..2502381) Escherichia coli str. K-12 substr. DH10B 6058941 YP_001731231.1 CDS yfbV NC_010473.1 2502464 2502919 R hypothetical protein complement(2502464..2502919) Escherichia coli str. K-12 substr. DH10B 6058948 YP_001731232.1 CDS ackA NC_010473.1 2503257 2504459 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 2503257..2504459 Escherichia coli str. K-12 substr. DH10B 6058957 YP_001731233.1 CDS pta NC_010473.1 2504534 2506678 D catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 2504534..2506678 Escherichia coli str. K-12 substr. DH10B 6058958 YP_001731234.1 CDS yfcC NC_010473.1 2506868 2508388 D hypothetical protein 2506868..2508388 Escherichia coli str. K-12 substr. DH10B 6058959 YP_001731235.1 CDS yfcD NC_010473.1 2508421 2508963 R NUDIX hydrolase complement(2508421..2508963) Escherichia coli str. K-12 substr. DH10B 6058967 YP_001731236.1 CDS yfcE NC_010473.1 2509021 2509575 R phosphodiesterase complement(2509021..2509575) Escherichia coli str. K-12 substr. DH10B 6058985 YP_001731237.1 CDS yfcF NC_010473.1 2509628 2510272 R hypothetical protein complement(2509628..2510272) Escherichia coli str. K-12 substr. DH10B 6058987 YP_001731238.1 CDS yfcG NC_010473.1 2510408 2511055 D glutathione S-transferase 2510408..2511055 Escherichia coli str. K-12 substr. DH10B 6059003 YP_001731239.1 CDS folX NC_010473.1 2511112 2511474 D catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 2511112..2511474 Escherichia coli str. K-12 substr. DH10B 6059004 YP_001731240.1 CDS yfcH NC_010473.1 2511495 2512388 D hypothetical protein 2511495..2512388 Escherichia coli str. K-12 substr. DH10B 6059011 YP_001731241.1 CDS yfcI NC_010473.1 2512436 2513326 R putative transposase complement(2512436..2513326) Escherichia coli str. K-12 substr. DH10B 6059012 YP_001731242.1 CDS hisP NC_010473.1 2513523 2514296 R histidine/lysine/arginine/ornithine transporter subunit complement(2513523..2514296) Escherichia coli str. K-12 substr. DH10B 6059023 YP_001731243.1 CDS hisM NC_010473.1 2514304 2515020 R histidine/lysine/arginine/ornithine ABC transporter membrane protein complement(2514304..2515020) Escherichia coli str. K-12 substr. DH10B 6059027 YP_001731244.1 CDS hisQ NC_010473.1 2515017 2515703 R histidine/lysine/arginine/ornithine ABC transporter membrane protein complement(2515017..2515703) Escherichia coli str. K-12 substr. DH10B 6059035 YP_001731245.1 CDS hisJ NC_010473.1 2515793 2516575 R histidine/lysine/arginine/ornithine ABC transporter periplasmic-binding protein complement(2515793..2516575) Escherichia coli str. K-12 substr. DH10B 6059041 YP_001731246.1 CDS argT NC_010473.1 2516796 2517578 R lysine/arginine/ornithine ABC transporter periplasmic-binding protein complement(2516796..2517578) Escherichia coli str. K-12 substr. DH10B 6059042 YP_001731247.1 CDS ubiX NC_010473.1 2517844 2518413 R catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(2517844..2518413) Escherichia coli str. K-12 substr. DH10B 6059050 YP_001731248.1 CDS purF NC_010473.1 2518508 2520025 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(2518508..2520025) Escherichia coli str. K-12 substr. DH10B 6059052 YP_001731249.1 CDS cvpA NC_010473.1 2520062 2520550 R membrane protein required for colicin V production; colicin V production protein complement(2520062..2520550) Escherichia coli str. K-12 substr. DH10B 6059056 YP_001731250.1 CDS dedD NC_010473.1 2520809 2521471 R hypothetical protein complement(2520809..2521471) Escherichia coli str. K-12 substr. DH10B 6059073 YP_001731251.1 CDS folC NC_010473.1 2521461 2522729 R bifunctional folylpolyglutamate synthase/ dihydrofolate synthase complement(2521461..2522729) Escherichia coli str. K-12 substr. DH10B 6059080 YP_001731252.1 CDS accD NC_010473.1 2522799 2523713 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta complement(2522799..2523713) Escherichia coli str. K-12 substr. DH10B 6059083 YP_001731253.1 CDS dedA NC_010473.1 2523869 2524528 R hypothetical protein complement(2523869..2524528) Escherichia coli str. K-12 substr. DH10B 6059125 YP_001731254.1 CDS truA NC_010473.1 2524611 2525423 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(2524611..2525423) Escherichia coli str. K-12 substr. DH10B 6059152 YP_001731255.1 CDS usg NC_010473.1 2525423 2526436 R putative semialdehyde dehydrogenase complement(2525423..2526436) Escherichia coli str. K-12 substr. DH10B 6059153 YP_001731256.1 CDS pdxB NC_010473.1 2526502 2527638 R erythronate-4-phosphate dehydrogenase complement(2526502..2527638) Escherichia coli str. K-12 substr. DH10B 6059173 YP_001731257.1 CDS flk NC_010473.1 2527737 2528732 D in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 2527737..2528732 Escherichia coli str. K-12 substr. DH10B 6059181 YP_001731258.1 CDS yfcJ NC_010473.1 2528729 2529907 R hypothetical protein complement(2528729..2529907) Escherichia coli str. K-12 substr. DH10B 6059200 YP_001731259.1 CDS fabB NC_010473.1 2530172 2531392 R FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase complement(2530172..2531392) Escherichia coli str. K-12 substr. DH10B 6059208 YP_001731260.1 CDS mnmC NC_010473.1 2531551 2533557 D catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 2531551..2533557 Escherichia coli str. K-12 substr. DH10B 6059219 YP_001731261.1 CDS yfcL NC_010473.1 2533678 2533956 R hypothetical protein complement(2533678..2533956) Escherichia coli str. K-12 substr. DH10B 6059220 YP_001731262.1 CDS yfcM NC_010473.1 2533990 2534538 R hypothetical protein complement(2533990..2534538) Escherichia coli str. K-12 substr. DH10B 6059231 YP_001731263.1 CDS yfcA NC_010473.1 2534538 2535347 R hypothetical protein complement(2534538..2535347) Escherichia coli str. K-12 substr. DH10B 6059256 YP_001731264.1 CDS mepA NC_010473.1 2535347 2536171 R D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase complement(2535347..2536171) Escherichia coli str. K-12 substr. DH10B 6059273 YP_001731265.1 CDS aroC NC_010473.1 2536175 2537260 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(2536175..2537260) Escherichia coli str. K-12 substr. DH10B 6059277 YP_001731266.1 CDS prmB NC_010473.1 2537295 2538227 R involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(2537295..2538227) Escherichia coli str. K-12 substr. DH10B 6059289 YP_001731267.1 CDS yfcN NC_010473.1 2538393 2538944 D hypothetical protein 2538393..2538944 Escherichia coli str. K-12 substr. DH10B 6059294 YP_001731268.1 CDS yfcO NC_010473.1 2539015 2539836 R hypothetical protein complement(2539015..2539836) Escherichia coli str. K-12 substr. DH10B 6059842 YP_001731269.1 CDS yfcP NC_010473.1 2539838 2540377 R fimbrial-like adhesin protein complement(2539838..2540377) Escherichia coli str. K-12 substr. DH10B 6059461 YP_001731270.1 CDS yfcQ NC_010473.1 2540374 2540862 R fimbrial-like adhesin protein complement(2540374..2540862) Escherichia coli str. K-12 substr. DH10B 6059701 YP_001731271.1 CDS yfcR NC_010473.1 2540859 2541371 R fimbrial-like adhesin protein complement(2540859..2541371) Escherichia coli str. K-12 substr. DH10B 6059755 YP_001731272.1 CDS yfcS NC_010473.1 2541371 2542123 R periplasmic pilus chaperone complement(2541371..2542123) Escherichia coli str. K-12 substr. DH10B 6059794 YP_001731273.1 CDS yfcT NC_010473.1 2542143 2543039 R outer membrane export usher protein complement(2542143..2543039) Escherichia coli str. K-12 substr. DH10B 6059867 YP_001731274.1 CDS yfcU NC_010473.1 2543052 2544788 R export usher protein complement(2543052..2544788) Escherichia coli str. K-12 substr. DH10B 6059880 YP_001731275.1 CDS yfcV NC_010473.1 2544870 2545433 R fimbrial-like adhesin protein complement(2544870..2545433) Escherichia coli str. K-12 substr. DH10B 6059886 YP_001731276.1 CDS sixA NC_010473.1 2546114 2546599 R phosphohistidine phosphatase complement(2546114..2546599) Escherichia coli str. K-12 substr. DH10B 6059891 YP_001731277.1 CDS fadJ NC_010473.1 2546802 2548946 R multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha complement(2546802..2548946) Escherichia coli str. K-12 substr. DH10B 6059893 YP_001731278.1 CDS fadI NC_010473.1 2548946 2550256 R FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase complement(2548946..2550256) Escherichia coli str. K-12 substr. DH10B 6059897 YP_001731279.1 CDS yfcZ NC_010473.1 2550437 2550721 R hypothetical protein complement(2550437..2550721) Escherichia coli str. K-12 substr. DH10B 6059903 YP_001731280.1 CDS fadL NC_010473.1 2551087 2552433 D long-chain fatty acid outer membrane transporter 2551087..2552433 Escherichia coli str. K-12 substr. DH10B 6059914 YP_001731281.1 CDS yfdF NC_010473.1 2552799 2553857 D hypothetical protein 2552799..2553857 Escherichia coli str. K-12 substr. DH10B 6059915 YP_001731282.1 CDS vacJ NC_010473.1 2554039 2554794 R lipoprotein complement(2554039..2554794) Escherichia coli str. K-12 substr. DH10B 6059415 YP_001731283.1 CDS yfdC NC_010473.1 2555088 2556020 D inner membrane protein 2555088..2556020 Escherichia coli str. K-12 substr. DH10B 6059916 YP_001731284.1 CDS intS NC_010473.1 2556332 2557489 D CPS-53 (KpLE1) prophage; prophage CPS-53 integrase 2556332..2557489 Escherichia coli str. K-12 substr. DH10B 6062425 YP_001731285.1 CDS yfdG NC_010473.1 2557642 2558004 D CPS-53 (KpLE1) prophage; bactoprenol-linked glucose translocase (flippase) 2557642..2558004 Escherichia coli str. K-12 substr. DH10B 6059920 YP_001731286.1 CDS yfdH NC_010473.1 2558001 2558921 D CPS-53 (KpLE1) prophage; bactoprenol glucosyl transferase 2558001..2558921 Escherichia coli str. K-12 substr. DH10B 6059921 YP_001731287.1 CDS yfdI NC_010473.1 2558918 2560249 D CPS-53 (KpLE1) prophage; inner membrane protein 2558918..2560249 Escherichia coli str. K-12 substr. DH10B 6059923 YP_001731288.1 CDS yfdK NC_010473.1 2560864 2561304 R CPS-53 (KpLE1) prophage; hypothetical protein complement(2560864..2561304) Escherichia coli str. K-12 substr. DH10B 6059196 YP_001731289.1 CDS yfdL NC_010473.1 2561331 2561849 R CPS-53 (KpLE1) prophage; hypothetical protein complement(2561331..2561849) Escherichia coli str. K-12 substr. DH10B 6059925 YP_001731290.1 CDS yfdM NC_010473.1 2561899 2562174 R CPS-53 (KpLE1) prophage; methyltransferase complement(2561899..2562174) Escherichia coli str. K-12 substr. DH10B 6059926 YP_001731291.1 CDS yfdN NC_010473.1 2562174 2562668 R CPS-53 (KpLE1) prophage; hypothetical protein complement(2562174..2562668) Escherichia coli str. K-12 substr. DH10B 6059927 YP_001731292.1 CDS yfdO NC_010473.1 2562665 2563033 R CPS-53 (KpLE1) prophage; defective phage replication protein O complement(2562665..2563033) Escherichia coli str. K-12 substr. DH10B 6059928 YP_001731293.1 CDS yfdP NC_010473.1 2563307 2563753 D CPS-53 (KpLE1) prophage; hypothetical protein 2563307..2563753 Escherichia coli str. K-12 substr. DH10B 6059930 YP_001731294.1 CDS yfdQ NC_010473.1 2563819 2564643 D CPS-53 (KpLE1) prophage; hypothetical protein 2563819..2564643 Escherichia coli str. K-12 substr. DH10B 6059934 YP_001731295.1 CDS yfdR NC_010473.1 2564771 2565307 D CPS-53 (KpLE1) prophage; hypothetical protein 2564771..2565307 Escherichia coli str. K-12 substr. DH10B 6059935 YP_001731296.1 CDS yfdS NC_010473.1 2565298 2565660 D CPS-53 (KpLE1) prophage; hypothetical protein 2565298..2565660 Escherichia coli str. K-12 substr. DH10B 6059937 YP_001731297.1 CDS yfdT NC_010473.1 2565660 2565965 D CPS-53 (KpLE1) prophage; hypothetical protein 2565660..2565965 Escherichia coli str. K-12 substr. DH10B 6059938 YP_001731298.1 CDS ypdJ NC_010473.1 2565881 2566021 D hypothetical protein 2565881..2566021 Escherichia coli str. K-12 substr. DH10B 6059939 YP_001731299.1 CDS torI NC_010473.1 2566097 2566297 D response regulator inhibitor for tor operon 2566097..2566297 Escherichia coli str. K-12 substr. DH10B 6059941 YP_001731300.1 CDS dsdC NC_010473.1 2566481 2567416 R regulates the synthesis and expression of the dsdXA operon and dadA gene; DNA-binding transcriptional regulator DsdC complement(2566481..2567416) Escherichia coli str. K-12 substr. DH10B 6059942 YP_001731301.1 CDS dsdX NC_010473.1 2567634 2568971 D member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; permease DsdX 2567634..2568971 Escherichia coli str. K-12 substr. DH10B 6059943 YP_001731302.1 CDS dsdA NC_010473.1 2568989 2570317 D catalyzes the formation of pyruvate from serine; D-serine dehydratase 2568989..2570317 Escherichia coli str. K-12 substr. DH10B 6059944 YP_001731303.1 CDS emrY NC_010473.1 2570425 2571963 R multidrug efflux system complement(2570425..2571963) Escherichia coli str. K-12 substr. DH10B 6059945 YP_001731304.1 CDS emrK NC_010473.1 2571963 2573126 R EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein component complement(2571963..2573126) Escherichia coli str. K-12 substr. DH10B 6059946 YP_001731305.1 CDS evgA NC_010473.1 2573542 2574156 D response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance; DNA-binding transcriptional activator EvgA 2573542..2574156 Escherichia coli str. K-12 substr. DH10B 6059949 YP_001731306.1 CDS yfdE NC_010473.1 2577810 2578955 R hypothetical protein complement(2577810..2578955) Escherichia coli str. K-12 substr. DH10B 6059950 YP_001731307.1 CDS yfdV NC_010473.1 2579029 2579973 R member of the AEC family of auxin efflux transporters; unknown function; putative transporter YfdV complement(2579029..2579973) Escherichia coli str. K-12 substr. DH10B 6059951 YP_001731308.1 CDS oxc NC_010473.1 2580043 2581737 R catalyzes the formation of formyl-CoA from oxalyl-CoA; putative oxalyl-CoA decarboxylase complement(2580043..2581737) Escherichia coli str. K-12 substr. DH10B 6059952 YP_001731309.1 CDS frc NC_010473.1 2581791 2583041 R catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA; formyl-coenzyme A transferase complement(2581791..2583041) Escherichia coli str. K-12 substr. DH10B 6059953 YP_001731310.1 CDS yfdX NC_010473.1 2583554 2584189 R hypothetical protein complement(2583554..2584189) Escherichia coli str. K-12 substr. DH10B 6059955 YP_001731311.1 CDS ypdI NC_010473.1 2584485 2584760 D lipoprotein involved in colanic acid biosynthesis 2584485..2584760 Escherichia coli str. K-12 substr. DH10B 6059957 YP_001731312.1 CDS yfdY NC_010473.1 2584837 2585079 R inner membrane protein complement(2584837..2585079) Escherichia coli str. K-12 substr. DH10B 6059958 YP_001731313.1 CDS lpxP NC_010473.1 2585432 2586352 D Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 2585432..2586352 Escherichia coli str. K-12 substr. DH10B 6059959 YP_001731314.1 CDS yfdZ NC_010473.1 2586844 2588082 R aminotransferase complement(2586844..2588082) Escherichia coli str. K-12 substr. DH10B 6059960 YP_001731315.1 CDS ypdA NC_010473.1 2588458 2590155 D sensory kinase in two-component system with YpdB 2588458..2590155 Escherichia coli str. K-12 substr. DH10B 6059961 YP_001731316.1 CDS ypdB NC_010473.1 2590170 2590904 D response regulator in two-component system withYpdA 2590170..2590904 Escherichia coli str. K-12 substr. DH10B 6059962 YP_001731317.1 CDS ypdC NC_010473.1 2590917 2591774 D DNA-binding protein 2590917..2591774 Escherichia coli str. K-12 substr. DH10B 6059963 YP_001731318.1 CDS ypdD NC_010473.1 2591777 2594272 R fused PTS enzymes: Hpr component; enzyme I component; enzyme IIA component complement(2591777..2594272) Escherichia coli str. K-12 substr. DH10B 6059967 YP_001731319.1 CDS ypdE NC_010473.1 2594297 2595334 R metalloprotein; exoaminopeptidase complement(2594297..2595334) Escherichia coli str. K-12 substr. DH10B 6059969 YP_001731320.1 CDS ypdF NC_010473.1 2595334 2596419 R Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase complement(2595334..2596419) Escherichia coli str. K-12 substr. DH10B 6059970 YP_001731321.1 CDS ypdG NC_010473.1 2596434 2597681 R enzyme IIC component of PTS complement(2596434..2597681) Escherichia coli str. K-12 substr. DH10B 6059971 YP_001731322.1 CDS ypdH NC_010473.1 2597703 2598029 R enzyme IIB component of PTS complement(2597703..2598029) Escherichia coli str. K-12 substr. DH10B 6059975 YP_001731323.1 CDS glk NC_010473.1 2598248 2599213 R catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase complement(2598248..2599213) Escherichia coli str. K-12 substr. DH10B 6059977 YP_001731324.1 CDS yfeO NC_010473.1 2599417 2600673 D hypothetical protein 2599417..2600673 Escherichia coli str. K-12 substr. DH10B 6059978 YP_001731325.1 CDS ypeC NC_010473.1 2600788 2601114 D hypothetical protein 2600788..2601114 Escherichia coli str. K-12 substr. DH10B 6059979 YP_001731326.1 CDS mntH NC_010473.1 2601255 2602493 R manganese transport protein MntH complement(2601255..2602493) Escherichia coli str. K-12 substr. DH10B 6059981 YP_001731327.1 CDS nupC NC_010473.1 2602829 2604031 D nucleoside (except guanosine) transporter 2602829..2604031 Escherichia coli str. K-12 substr. DH10B 6059982 YP_001731328.1 CDS insL-3 NC_010473.1 2604118 2605230 D IS186/IS421 transposase 2604118..2605230 Escherichia coli str. K-12 substr. DH10B 6059984 YP_001731329.1 CDS yfeA NC_010473.1 2605430 2607619 R diguanylate cyclase complement(2605430..2607619) Escherichia coli str. K-12 substr. DH10B 6059989 YP_001731330.1 CDS yfeC NC_010473.1 2608254 2608598 D DNA-binding transcriptional regulator 2608254..2608598 Escherichia coli str. K-12 substr. DH10B 6059986 YP_001731331.1 CDS yfeD NC_010473.1 2608600 2608992 D DNA-binding transcriptional regulator 2608600..2608992 Escherichia coli str. K-12 substr. DH10B 6059991 YP_001731332.1 CDS gltX NC_010473.1 2609044 2610459 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(2609044..2610459) Escherichia coli str. K-12 substr. DH10B 6059993 YP_001731333.1 CDS xapR NC_010473.1 2611380 2612264 R DNA-binding transcriptional activator XapR complement(2611380..2612264) Escherichia coli str. K-12 substr. DH10B 6059514 YP_001731334.1 CDS xapB NC_010473.1 2612516 2613772 R xanthosine transporter complement(2612516..2613772) Escherichia coli str. K-12 substr. DH10B 6059996 YP_001731335.1 CDS xapA NC_010473.1 2613832 2614665 R catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase complement(2613832..2614665) Escherichia coli str. K-12 substr. DH10B 6059999 YP_001731336.1 CDS yfeN NC_010473.1 2614914 2615678 D hypothetical protein 2614914..2615678 Escherichia coli str. K-12 substr. DH10B 6060002 YP_001731337.1 CDS yfeR NC_010473.1 2615717 2616643 R DNA-binding transcriptional regulator complement(2615717..2616643) Escherichia coli str. K-12 substr. DH10B 6060004 YP_001731338.1 CDS yfeH NC_010473.1 2616733 2617731 D inner membrane protein 2616733..2617731 Escherichia coli str. K-12 substr. DH10B 6060005 YP_001731339.1 CDS ypeB NC_010473.1 2617728 2617946 R hypothetical protein complement(2617728..2617946) Escherichia coli str. K-12 substr. DH10B 6060006 YP_001731340.1 CDS ligA NC_010473.1 2617948 2619963 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(2617948..2619963) Escherichia coli str. K-12 substr. DH10B 6060009 YP_001731341.1 CDS zipA NC_010473.1 2620034 2621020 R interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA complement(2620034..2621020) Escherichia coli str. K-12 substr. DH10B 6060013 YP_001731342.1 CDS cysZ NC_010473.1 2621250 2622011 D putative role in sulfur assimilation; putative sulfate transport protein CysZ 2621250..2622011 Escherichia coli str. K-12 substr. DH10B 6060018 YP_001731343.1 CDS cysK NC_010473.1 2622196 2623167 D CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 2622196..2623167 Escherichia coli str. K-12 substr. DH10B 6060020 YP_001731344.1 CDS ptsH NC_010473.1 2623551 2623808 D PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr 2623551..2623808 Escherichia coli str. K-12 substr. DH10B 6060021 YP_001731345.1 CDS ptsI NC_010473.1 2623853 2625580 D Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 2623853..2625580 Escherichia coli str. K-12 substr. DH10B 6060023 YP_001731346.1 CDS crr NC_010473.1 2625621 2626130 D functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter 2625621..2626130 Escherichia coli str. K-12 substr. DH10B 6060024 YP_001731347.1 CDS pdxK NC_010473.1 2626173 2627024 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase complement(2626173..2627024) Escherichia coli str. K-12 substr. DH10B 6060028 YP_001731348.1 CDS yfeK NC_010473.1 2627129 2627503 D hypothetical protein 2627129..2627503 Escherichia coli str. K-12 substr. DH10B 6060033 YP_001731349.1 CDS yfeS NC_010473.1 2627536 2628270 D hypothetical protein 2627536..2628270 Escherichia coli str. K-12 substr. DH10B 6060034 YP_001731350.1 CDS cysM NC_010473.1 2628459 2629370 R catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B complement(2628459..2629370) Escherichia coli str. K-12 substr. DH10B 6060035 YP_001731351.1 CDS cysA NC_010473.1 2629504 2630601 R sulfate/thiosulfate transporter subunit complement(2629504..2630601) Escherichia coli str. K-12 substr. DH10B 6060036 YP_001731352.1 CDS cysW NC_010473.1 2630591 2631466 R Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit complement(2630591..2631466) Escherichia coli str. K-12 substr. DH10B 6060038 YP_001731353.1 CDS cysU NC_010473.1 2631466 2632299 R sulfate/thiosulfate transporter subunit complement(2631466..2632299) Escherichia coli str. K-12 substr. DH10B 6060041 YP_001731354.1 CDS cysP NC_010473.1 2632299 2633315 R thiosulfate transporter subunit complement(2632299..2633315) Escherichia coli str. K-12 substr. DH10B 6060042 YP_001731355.1 CDS ucpA NC_010473.1 2633619 2634410 R short chain dehydrogenase complement(2633619..2634410) Escherichia coli str. K-12 substr. DH10B 6060043 YP_001731356.1 CDS yfeT NC_010473.1 2634539 2635396 R DNA-binding transcriptional regulator complement(2634539..2635396) Escherichia coli str. K-12 substr. DH10B 6060045 YP_001731357.1 CDS murQ NC_010473.1 2635560 2636456 D catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 2635560..2636456 Escherichia coli str. K-12 substr. DH10B 6060046 YP_001731358.1 CDS murP NC_010473.1 2636460 2637884 D belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunit IIBC 2636460..2637884 Escherichia coli str. K-12 substr. DH10B 6060047 YP_001731359.1 CDS yfeW NC_010473.1 2637889 2639193 D hypothetical protein 2637889..2639193 Escherichia coli str. K-12 substr. DH10B 6060048 YP_001731360.1 CDS yfeX NC_010473.1 2639433 2640332 R hypothetical protein complement(2639433..2640332) Escherichia coli str. K-12 substr. DH10B 6060050 YP_001731361.1 CDS yfeY NC_010473.1 2640428 2641003 R hypothetical protein complement(2640428..2641003) Escherichia coli str. K-12 substr. DH10B 6060051 YP_001731362.1 CDS yfeZ NC_010473.1 2641064 2641513 R inner membrane protein complement(2641064..2641513) Escherichia coli str. K-12 substr. DH10B 6060052 YP_001731363.1 CDS ypeA NC_010473.1 2641500 2641925 R putative acetyltransferase complement(2641500..2641925) Escherichia coli str. K-12 substr. DH10B 6060055 YP_001731364.1 CDS amiA NC_010473.1 2642139 2643008 D N-acetylmuramoyl-l-alanine amidase I 2642139..2643008 Escherichia coli str. K-12 substr. DH10B 6060057 YP_001731365.1 CDS hemF NC_010473.1 2643012 2643911 D catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 2643012..2643911 Escherichia coli str. K-12 substr. DH10B 6060058 YP_001731366.1 CDS yfeG NC_010473.1 2643917 2644969 R activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR complement(2643917..2644969) Escherichia coli str. K-12 substr. DH10B 6060061 YP_001731367.1 CDS yffI NC_010473.1 2645015 2645515 R ethanolamine utilization carboxysome structural protein complement(2645015..2645515) Escherichia coli str. K-12 substr. DH10B 6060063 YP_001731368.1 CDS eutL NC_010473.1 2645528 2646187 R ethanolamine utilization carboxysome structural protein complement(2645528..2646187) Escherichia coli str. K-12 substr. DH10B 6060064 YP_001731369.1 CDS eutC NC_010473.1 2646197 2647084 R catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit complement(2646197..2647084) Escherichia coli str. K-12 substr. DH10B 6060065 YP_001731370.1 CDS eutB NC_010473.1 2647105 2648466 R ethanolamine ammonia-lyase, large subunit, heavy chain complement(2647105..2648466) Escherichia coli str. K-12 substr. DH10B 6060066 YP_001731371.1 CDS intZ NC_010473.1 2648558 2649853 D CPZ-55 prophage; integrase 2648558..2649853 Escherichia coli str. K-12 substr. DH10B 6060069 YP_001731372.1 CDS yffL NC_010473.1 2650044 2650685 D CPZ-55 prophage; hypothetical protein 2650044..2650685 Escherichia coli str. K-12 substr. DH10B 6060070 YP_001731373.1 CDS yffM NC_010473.1 2651155 2651400 D CPZ-55 prophage; hypothetical protein 2651155..2651400 Escherichia coli str. K-12 substr. DH10B 6060072 YP_001731374.1 CDS yffN NC_010473.1 2651397 2651780 D CPZ-55 prophage; hypothetical protein 2651397..2651780 Escherichia coli str. K-12 substr. DH10B 6060075 YP_001731375.1 CDS yffO NC_010473.1 2651898 2652314 D CPZ-55 prophage; hypothetical protein 2651898..2652314 Escherichia coli str. K-12 substr. DH10B 6060078 YP_001731376.1 CDS yffP NC_010473.1 2652311 2652904 D CPZ-55 prophage; hypothetical protein 2652311..2652904 Escherichia coli str. K-12 substr. DH10B 6060079 YP_001731377.1 CDS yffQ NC_010473.1 2653364 2653756 D CPZ-55 prophage; hypothetical protein 2653364..2653756 Escherichia coli str. K-12 substr. DH10B 6060098 YP_001731378.1 CDS yffR NC_010473.1 2653767 2654159 D CPZ-55 prophage; hypothetical protein 2653767..2654159 Escherichia coli str. K-12 substr. DH10B 6060099 YP_001731379.1 CDS yffS NC_010473.1 2654280 2655119 D CPZ-55 prophage; hypothetical protein 2654280..2655119 Escherichia coli str. K-12 substr. DH10B 6060102 YP_001731380.1 CDS eutA NC_010473.1 2655268 2656671 R ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase complement(2655268..2656671) Escherichia coli str. K-12 substr. DH10B 6060106 YP_001731381.1 CDS eutH NC_010473.1 2656668 2657894 R inner membrane protein complement(2656668..2657894) Escherichia coli str. K-12 substr. DH10B 6060107 YP_001731382.1 CDS eutG NC_010473.1 2658111 2659298 R alcohol dehydrogenase in ethanolamine utilization complement(2658111..2659298) Escherichia coli str. K-12 substr. DH10B 6060108 YP_001731383.1 CDS eutJ NC_010473.1 2659288 2660124 R chaperonin, ethanolamine utilization protein complement(2659288..2660124) Escherichia coli str. K-12 substr. DH10B 6060109 YP_001731384.1 CDS eutE NC_010473.1 2660135 2661538 R aldehyde dehydrogenase complement(2660135..2661538) Escherichia coli str. K-12 substr. DH10B 6060112 YP_001731385.1 CDS cchB NC_010473.1 2661550 2661837 R ethanolamine utilization carboxysome structural protein complement(2661550..2661837) Escherichia coli str. K-12 substr. DH10B 6060114 YP_001731386.1 CDS cchA NC_010473.1 2661944 2662237 R ethanolamine utilization carboxysome structural protein complement(2661944..2662237) Escherichia coli str. K-12 substr. DH10B 6060118 YP_001731387.1 CDS eutD NC_010473.1 2662276 2663292 R in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase complement(2662276..2663292) Escherichia coli str. K-12 substr. DH10B 6060119 YP_001731388.1 CDS eutT NC_010473.1 2663289 2664092 R cobalamin adenosyltransferase in ethanolamine utilization complement(2663289..2664092) Escherichia coli str. K-12 substr. DH10B 6060127 YP_001731389.1 CDS eutQ NC_010473.1 2664089 2664790 R hypothetical protein complement(2664089..2664790) Escherichia coli str. K-12 substr. DH10B 6060129 YP_001731390.1 CDS eutP NC_010473.1 2664765 2665244 R hypothetical protein complement(2664765..2665244) Escherichia coli str. K-12 substr. DH10B 6060130 YP_001731391.1 CDS ypfE NC_010473.1 2665257 2665592 R ethanol utilization carboxysome structural protein complement(2665257..2665592) Escherichia coli str. K-12 substr. DH10B 6060132 YP_001731392.1 CDS maeB NC_010473.1 2665885 2668164 R NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme complement(2665885..2668164) Escherichia coli str. K-12 substr. DH10B 6060134 YP_001731393.1 CDS talA NC_010473.1 2668453 2669403 D transaldolase A 2668453..2669403 Escherichia coli str. K-12 substr. DH10B 6060135 YP_001731394.1 CDS tktB NC_010473.1 2669423 2671426 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2669423..2671426 Escherichia coli str. K-12 substr. DH10B 6060140 YP_001731395.1 CDS ypfG NC_010473.1 2671521 2672564 R hypothetical protein complement(2671521..2672564) Escherichia coli str. K-12 substr. DH10B 6060142 YP_001731396.1 CDS yffH NC_010473.1 2672690 2673265 R NUDIX hydrolase complement(2672690..2673265) Escherichia coli str. K-12 substr. DH10B 6060143 YP_001731397.1 CDS aegA NC_010473.1 2673333 2675312 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); putative oxidoreductase Fe-S binding subunit complement(2673333..2675312) Escherichia coli str. K-12 substr. DH10B 6060146 YP_001731398.1 CDS narQ NC_010473.1 2675518 2677218 D nitrate/nitrite sensor protein NarQ 2675518..2677218 Escherichia coli str. K-12 substr. DH10B 6060147 YP_001731399.1 CDS acrD NC_010473.1 2677382 2680495 D aminoglycoside/multidrug efflux system 2677382..2680495 Escherichia coli str. K-12 substr. DH10B 6060148 YP_001731400.1 CDS yffB NC_010473.1 2681034 2681390 D hypothetical protein 2681034..2681390 Escherichia coli str. K-12 substr. DH10B 6060150 YP_001731401.1 CDS dapE NC_010473.1 2681394 2682521 D dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2681394..2682521 Escherichia coli str. K-12 substr. DH10B 6060158 YP_001731402.1 CDS ypfN NC_010473.1 2682549 2682749 D hypothetical protein 2682549..2682749 Escherichia coli str. K-12 substr. DH10B 6060160 YP_001731403.1 CDS ypfH NC_010473.1 2682859 2683557 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YpfH complement(2682859..2683557) Escherichia coli str. K-12 substr. DH10B 6060163 YP_001731404.1 CDS ypfI NC_010473.1 2683631 2685646 R hydrolase complement(2683631..2685646) Escherichia coli str. K-12 substr. DH10B 6060168 YP_001731405.1 CDS ypfJ NC_010473.1 2685661 2686524 R hypothetical protein complement(2685661..2686524) Escherichia coli str. K-12 substr. DH10B 6060172 YP_001731406.1 CDS purC NC_010473.1 2686692 2687405 R catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase complement(2686692..2687405) Escherichia coli str. K-12 substr. DH10B 6060174 YP_001731407.1 CDS nlpB NC_010473.1 2687618 2688652 R lipoprotein complement(2687618..2688652) Escherichia coli str. K-12 substr. DH10B 6060179 YP_001731408.1 CDS dapA NC_010473.1 2688669 2689547 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(2688669..2689547) Escherichia coli str. K-12 substr. DH10B 6060180 YP_001731409.1 CDS gcvR NC_010473.1 2689693 2690265 D negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 2689693..2690265 Escherichia coli str. K-12 substr. DH10B 6060184 YP_001731410.1 CDS bcp NC_010473.1 2690265 2690735 D bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 2690265..2690735 Escherichia coli str. K-12 substr. DH10B 6060187 YP_001731411.1 CDS hyfA NC_010473.1 2690988 2691605 D hydrogenase 4, 4Fe-4S subunit 2690988..2691605 Escherichia coli str. K-12 substr. DH10B 6060192 YP_001731412.1 CDS hyfB NC_010473.1 2691605 2693623 D hydrogenase 4 subunit B 2691605..2693623 Escherichia coli str. K-12 substr. DH10B 6060195 YP_001731413.1 CDS hyfC NC_010473.1 2693634 2694581 D hydrogenase 4, membrane subunit 2693634..2694581 Escherichia coli str. K-12 substr. DH10B 6060209 YP_001731414.1 CDS hyfD NC_010473.1 2694598 2696037 D hydrogenase 4 subunit D 2694598..2696037 Escherichia coli str. K-12 substr. DH10B 6060212 YP_001731415.1 CDS hyfE NC_010473.1 2696049 2696699 D interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide; hydrogenase 4 membrane subunit 2696049..2696699 Escherichia coli str. K-12 substr. DH10B 6060213 YP_001731416.1 CDS hyfF NC_010473.1 2696704 2698284 D hydrogenase 4 subunit F 2696704..2698284 Escherichia coli str. K-12 substr. DH10B 6060216 YP_001731417.1 CDS hyfG NC_010473.1 2698274 2699941 D hydrogenase 4 subunit 2698274..2699941 Escherichia coli str. K-12 substr. DH10B 6060217 YP_001731418.1 CDS hyfH NC_010473.1 2699951 2700496 D probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far; hydrogenase 4 subunit H 2699951..2700496 Escherichia coli str. K-12 substr. DH10B 6060219 YP_001731419.1 CDS hyfI NC_010473.1 2700493 2701251 D hydrogenase 4, Fe-S subunit 2700493..2701251 Escherichia coli str. K-12 substr. DH10B 6060222 YP_001731420.1 CDS hyfJ NC_010473.1 2701244 2701657 D processing element hydrogenase 4 2701244..2701657 Escherichia coli str. K-12 substr. DH10B 6060227 YP_001731421.1 CDS hyfR NC_010473.1 2701687 2703699 D DNA-binding transcriptional activator, formate sensing 2701687..2703699 Escherichia coli str. K-12 substr. DH10B 6060233 YP_001731422.1 CDS focB NC_010473.1 2703721 2704569 D inner membrane protein presumed to act as a formate transporter; member of the hyf operon; putative formate transporter 2703721..2704569 Escherichia coli str. K-12 substr. DH10B 6060234 YP_001731423.1 CDS yfgO NC_010473.1 2704607 2705668 R inner membrane protein complement(2704607..2705668) Escherichia coli str. K-12 substr. DH10B 6060243 YP_001731424.1 CDS yfgC NC_010473.1 2705881 2707344 D peptidase 2705881..2707344 Escherichia coli str. K-12 substr. DH10B 6060246 YP_001731425.1 CDS yfgD NC_010473.1 2707365 2707724 D oxidoreductase 2707365..2707724 Escherichia coli str. K-12 substr. DH10B 6060255 YP_001731426.1 CDS hda NC_010473.1 2707862 2708608 R controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor complement(2707862..2708608) Escherichia coli str. K-12 substr. DH10B 6060260 YP_001731427.1 CDS uraA NC_010473.1 2708658 2709947 R uracil transporter complement(2708658..2709947) Escherichia coli str. K-12 substr. DH10B 6060191 YP_001731428.1 CDS upp NC_010473.1 2710033 2710659 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(2710033..2710659) Escherichia coli str. K-12 substr. DH10B 6060267 YP_001731429.1 CDS purM NC_010473.1 2710984 2712021 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 2710984..2712021 Escherichia coli str. K-12 substr. DH10B 6060270 YP_001731430.1 CDS purN NC_010473.1 2712021 2712659 D glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 2712021..2712659 Escherichia coli str. K-12 substr. DH10B 6060274 YP_001731431.1 CDS ppk NC_010473.1 2712831 2714897 D catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 2712831..2714897 Escherichia coli str. K-12 substr. DH10B 6060278 YP_001731432.1 CDS ppx NC_010473.1 2714902 2716443 D exopolyphosphatase 2714902..2716443 Escherichia coli str. K-12 substr. DH10B 6060279 YP_001731433.1 CDS yfgF NC_010473.1 2716482 2718725 R inner membrane protein complement(2716482..2718725) Escherichia coli str. K-12 substr. DH10B 6060280 YP_001731434.1 CDS yfgG NC_010473.1 2719077 2719268 D hypothetical protein 2719077..2719268 Escherichia coli str. K-12 substr. DH10B 6060281 YP_001731435.1 CDS yfgH NC_010473.1 2719579 2720097 D outer membrane lipoprotein 2719579..2720097 Escherichia coli str. K-12 substr. DH10B 6060284 YP_001731436.1 CDS yfgI NC_010473.1 2720113 2720652 D hypothetical protein 2720113..2720652 Escherichia coli str. K-12 substr. DH10B 6060285 YP_001731437.1 CDS guaA NC_010473.1 2720745 2722322 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(2720745..2722322) Escherichia coli str. K-12 substr. DH10B 6060288 YP_001731438.1 CDS guaB NC_010473.1 2722391 2723857 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(2722391..2723857) Escherichia coli str. K-12 substr. DH10B 6060291 YP_001731439.1 CDS xseA NC_010473.1 2724019 2725389 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 2724019..2725389 Escherichia coli str. K-12 substr. DH10B 6060294 YP_001731440.1 CDS yfgJ NC_010473.1 2725386 2725601 R hypothetical protein complement(2725386..2725601) Escherichia coli str. K-12 substr. DH10B 6060295 YP_001731441.1 CDS engA NC_010473.1 2725671 2727143 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(2725671..2727143) Escherichia coli str. K-12 substr. DH10B 6060298 YP_001731442.1 CDS yfgL NC_010473.1 2727261 2728439 R with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL complement(2727261..2728439) Escherichia coli str. K-12 substr. DH10B 6060301 YP_001731443.1 CDS yfgM NC_010473.1 2728450 2729070 R hypothetical protein complement(2728450..2729070) Escherichia coli str. K-12 substr. DH10B 6060310 YP_001731444.1 CDS hisS NC_010473.1 2729088 2730362 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(2729088..2730362) Escherichia coli str. K-12 substr. DH10B 6060322 YP_001731445.1 CDS ispG NC_010473.1 2730473 2731591 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(2730473..2731591) Escherichia coli str. K-12 substr. DH10B 6060323 YP_001731446.1 CDS yfgA NC_010473.1 2731618 2732631 R cytoskeletal protein RodZ complement(2731618..2732631) Escherichia coli str. K-12 substr. DH10B 6060342 YP_001731447.1 CDS yfgB NC_010473.1 2732916 2734070 R 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N complement(2732916..2734070) Escherichia coli str. K-12 substr. DH10B 6060344 YP_001731448.1 CDS ndk NC_010473.1 2734220 2734651 R catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase complement(2734220..2734651) Escherichia coli str. K-12 substr. DH10B 6060348 YP_001731449.1 CDS pbpC NC_010473.1 2734800 2737112 R penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C complement(2734800..2737112) Escherichia coli str. K-12 substr. DH10B 6060350 YP_001731450.1 CDS yfhM NC_010473.1 2737113 2742074 R hypothetical protein complement(2737113..2742074) Escherichia coli str. K-12 substr. DH10B 6060351 YP_001731451.1 CDS sseA NC_010473.1 2742281 2743126 D catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 2742281..2743126 Escherichia coli str. K-12 substr. DH10B 6060352 YP_001731452.1 CDS sseB NC_010473.1 2743944 2744720 R enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB complement(2743944..2744720) Escherichia coli str. K-12 substr. DH10B 6058783 YP_001731453.1 CDS pepB NC_010473.1 2744862 2746145 R catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B complement(2744862..2746145) Escherichia coli str. K-12 substr. DH10B 6060361 YP_001731454.1 CDS yfhJ NC_010473.1 2746323 2746523 R hypothetical protein complement(2746323..2746523) Escherichia coli str. K-12 substr. DH10B 6060366 YP_001731455.1 CDS fdx NC_010473.1 2746535 2746870 R [2Fe-2S] ferredoxin complement(2746535..2746870) Escherichia coli str. K-12 substr. DH10B 6060367 YP_001731456.1 CDS hscA NC_010473.1 2746872 2748722 R involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA complement(2746872..2748722) Escherichia coli str. K-12 substr. DH10B 6060385 YP_001731457.1 CDS hscB NC_010473.1 2748739 2749254 R J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB complement(2748739..2749254) Escherichia coli str. K-12 substr. DH10B 6060391 YP_001731458.1 CDS iscA NC_010473.1 2749350 2749673 R forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein complement(2749350..2749673) Escherichia coli str. K-12 substr. DH10B 6060393 YP_001731459.1 CDS iscU NC_010473.1 2749690 2750076 R scaffold protein complement(2749690..2750076) Escherichia coli str. K-12 substr. DH10B 6060399 YP_001731460.1 CDS iscS NC_010473.1 2750104 2751318 R catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase complement(2750104..2751318) Escherichia coli str. K-12 substr. DH10B 6060401 YP_001731461.1 CDS iscR NC_010473.1 2751430 2751918 R regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR complement(2751430..2751918) Escherichia coli str. K-12 substr. DH10B 6060406 YP_001731462.1 CDS yfhQ NC_010473.1 2752370 2753110 R methyltransferase complement(2752370..2753110) Escherichia coli str. K-12 substr. DH10B 6060416 YP_001731463.1 CDS suhB NC_010473.1 2753229 2754032 D inositol monophosphatase 2753229..2754032 Escherichia coli str. K-12 substr. DH10B 6060418 YP_001731464.1 CDS yfhR NC_010473.1 2754150 2755031 D peptidase 2754150..2755031 Escherichia coli str. K-12 substr. DH10B 6060442 YP_001731465.1 CDS csiE NC_010473.1 2755222 2756502 D stationary phase inducible protein CsiE 2755222..2756502 Escherichia coli str. K-12 substr. DH10B 6060443 YP_001731466.1 CDS hcaT NC_010473.1 2756494 2757633 R putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; putative 3-phenylpropionic acid transporter complement(2756494..2757633) Escherichia coli str. K-12 substr. DH10B 6060444 YP_001731467.1 CDS hcaR NC_010473.1 2757793 2758683 R activator of 3-phenylpropionic acid catabolism; DNA-binding transcriptional regulator HcaR complement(2757793..2758683) Escherichia coli str. K-12 substr. DH10B 6060445 YP_001731468.1 CDS hcaE NC_010473.1 2758819 2760180 D 3-phenylpropionate dioxygenase, large (alpha) subunit 2758819..2760180 Escherichia coli str. K-12 substr. DH10B 6062285 YP_001731469.1 CDS hcaF NC_010473.1 2760177 2760695 D 3-phenylpropionate dioxygenase subunit beta 2760177..2760695 Escherichia coli str. K-12 substr. DH10B 6060450 YP_001731470.1 CDS hcaC NC_010473.1 2760695 2761015 D 3-phenylpropionate dioxygenase ferredoxin subunit 2760695..2761015 Escherichia coli str. K-12 substr. DH10B 6060457 YP_001731471.1 CDS hcaB NC_010473.1 2761012 2761824 D Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate; 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase 2761012..2761824 Escherichia coli str. K-12 substr. DH10B 6060465 YP_001731472.1 CDS hcaD NC_010473.1 2761834 2763036 D phenylpropionate dioxygenase ferredoxin reductase subunit 2761834..2763036 Escherichia coli str. K-12 substr. DH10B 6060470 YP_001731473.1 CDS yphA NC_010473.1 2763061 2763555 D inner membrane protein 2763061..2763555 Escherichia coli str. K-12 substr. DH10B 6060474 YP_001731474.1 CDS yphB NC_010473.1 2763603 2764475 R hypothetical protein complement(2763603..2764475) Escherichia coli str. K-12 substr. DH10B 6060475 YP_001731475.1 CDS yphC NC_010473.1 2764487 2765548 R oxidoreductase, Zn-dependent and NAD(P)-binding complement(2764487..2765548) Escherichia coli str. K-12 substr. DH10B 6060478 YP_001731476.1 CDS yphD NC_010473.1 2765614 2766612 R sugar ABC transporter membrane protein complement(2765614..2766612) Escherichia coli str. K-12 substr. DH10B 6060479 YP_001731477.1 CDS yphE NC_010473.1 2766637 2768148 R sugar ABC transporter ATP-binding protein complement(2766637..2768148) Escherichia coli str. K-12 substr. DH10B 6060480 YP_001731478.1 CDS yphF NC_010473.1 2768171 2769154 R sugar ABC transporter periplasmic-binding protein complement(2768171..2769154) Escherichia coli str. K-12 substr. DH10B 6060482 YP_001731479.1 CDS yphG NC_010473.1 2769251 2772532 R hypothetical protein complement(2769251..2772532) Escherichia coli str. K-12 substr. DH10B 6060483 YP_001731480.1 CDS yphH NC_010473.1 2772650 2773843 D DNA-binding transcriptional regulator 2772650..2773843 Escherichia coli str. K-12 substr. DH10B 6060484 YP_001731481.1 CDS glyA NC_010473.1 2774041 2775294 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(2774041..2775294) Escherichia coli str. K-12 substr. DH10B 6060030 YP_001731482.1 CDS hmp NC_010473.1 2775622 2776812 D flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 2775622..2776812 Escherichia coli str. K-12 substr. DH10B 6060485 YP_001731483.1 CDS glnB NC_010473.1 2776857 2777195 R indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 complement(2776857..2777195) Escherichia coli str. K-12 substr. DH10B 6060490 YP_001731484.1 CDS yfhA NC_010473.1 2777256 2778590 R two component system DNA-binding response regulator complement(2777256..2778590) Escherichia coli str. K-12 substr. DH10B 6060492 YP_001731485.1 CDS yfhG NC_010473.1 2778580 2779293 R hypothetical protein complement(2778580..2779293) Escherichia coli str. K-12 substr. DH10B 6060495 YP_001731486.1 CDS yfhK NC_010473.1 2779458 2780885 R sensory kinase in two-component system complement(2779458..2780885) Escherichia coli str. K-12 substr. DH10B 6060497 YP_001731487.1 CDS purL NC_010473.1 2781443 2785330 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase complement(2781443..2785330) Escherichia coli str. K-12 substr. DH10B 6060231 YP_001731488.1 CDS yfhD NC_010473.1 2785726 2787144 D YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; putative transglycosylase 2785726..2787144 Escherichia coli str. K-12 substr. DH10B 6060524 YP_001731489.1 CDS tadA NC_010473.1 2787141 2787644 R tRNA-specific adenosine deaminase complement(2787141..2787644) Escherichia coli str. K-12 substr. DH10B 6060542 YP_001731490.1 CDS yfhB NC_010473.1 2787702 2788337 R hypothetical protein complement(2787702..2788337) Escherichia coli str. K-12 substr. DH10B 6060552 YP_001731491.1 CDS yfhH NC_010473.1 2788546 2789394 D putative DNA-binding transcriptional regulator 2788546..2789394 Escherichia coli str. K-12 substr. DH10B 6060590 YP_001731492.1 CDS yfhL NC_010473.1 2789450 2789710 D 4Fe-4S binding protein 2789450..2789710 Escherichia coli str. K-12 substr. DH10B 6060602 YP_001731493.1 CDS pdxJ NC_010473.1 2790785 2791516 R involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase complement(2790785..2791516) Escherichia coli str. K-12 substr. DH10B 6060622 YP_001731494.1 CDS recO NC_010473.1 2791528 2792256 R involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO complement(2791528..2792256) Escherichia coli str. K-12 substr. DH10B 6060631 YP_001731495.1 CDS era NC_010473.1 2792268 2793173 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(2792268..2793173) Escherichia coli str. K-12 substr. DH10B 6060633 YP_001731496.1 CDS rnc NC_010473.1 2793170 2793850 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(2793170..2793850) Escherichia coli str. K-12 substr. DH10B 6060636 YP_001731497.1 CDS lepB NC_010473.1 2794122 2795096 R catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I complement(2794122..2795096) Escherichia coli str. K-12 substr. DH10B 6060642 YP_001731498.1 CDS lepA NC_010473.1 2795112 2796911 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(2795112..2796911) Escherichia coli str. K-12 substr. DH10B 6060657 YP_001731499.1 CDS rseC NC_010473.1 2797109 2797588 R protein involved in reduction of the SoxR iron-sulfur cluster; involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC complement(2797109..2797588) Escherichia coli str. K-12 substr. DH10B 6060663 YP_001731500.1 CDS rseB NC_010473.1 2797585 2798541 R periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE complement(2797585..2798541) Escherichia coli str. K-12 substr. DH10B 6060665 YP_001731501.1 CDS rseA NC_010473.1 2798541 2799191 R anti-RNA polymerase sigma factor SigE complement(2798541..2799191) Escherichia coli str. K-12 substr. DH10B 6060667 YP_001731502.1 CDS rpoE NC_010473.1 2799224 2799799 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE complement(2799224..2799799) Escherichia coli str. K-12 substr. DH10B 6060683 YP_001731503.1 CDS nadB NC_010473.1 2800207 2801829 D catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 2800207..2801829 Escherichia coli str. K-12 substr. DH10B 6060695 YP_001731504.1 CDS yfiC NC_010473.1 2801814 2802551 R S-adenosyl-L-methionine-dependent methyltransferase complement(2801814..2802551) Escherichia coli str. K-12 substr. DH10B 6060703 YP_001731505.1 CDS srmB NC_010473.1 2802683 2804017 D facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 2802683..2804017 Escherichia coli str. K-12 substr. DH10B 6060710 YP_001731506.1 CDS yfiE NC_010473.1 2804226 2805107 R DNA-binding transcriptional regulator complement(2804226..2805107) Escherichia coli str. K-12 substr. DH10B 6060729 YP_001731507.1 CDS yfiK NC_010473.1 2805210 2805797 D neutral amino-acid efflux protein 2805210..2805797 Escherichia coli str. K-12 substr. DH10B 6060738 YP_001731508.1 CDS yfiD NC_010473.1 2805853 2806236 R stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA complement(2805853..2806236) Escherichia coli str. K-12 substr. DH10B 6060746 YP_001731509.1 CDS ung NC_010473.1 2806541 2807230 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 2806541..2807230 Escherichia coli str. K-12 substr. DH10B 6060754 YP_001731510.1 CDS yfiF NC_010473.1 2807278 2808315 R putative methyltransferase complement(2807278..2808315) Escherichia coli str. K-12 substr. DH10B 6060763 YP_001731511.1 CDS trxC NC_010473.1 2808522 2808941 D thioredoxin 2 2808522..2808941 Escherichia coli str. K-12 substr. DH10B 6060770 YP_001731512.1 CDS yfiP NC_010473.1 2809010 2809708 D hypothetical protein 2809010..2809708 Escherichia coli str. K-12 substr. DH10B 6060082 YP_001731513.1 CDS yfiQ NC_010473.1 2809740 2812400 D fused acyl-CoA synthetase: NAD(P)-binding subunit; ATP-binding subunit 2809740..2812400 Escherichia coli str. K-12 substr. DH10B 6060089 YP_001731514.1 CDS pssA NC_010473.1 2812514 2813869 D catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 2812514..2813869 Escherichia coli str. K-12 substr. DH10B 6060093 YP_001731515.1 CDS yfiM NC_010473.1 2813966 2814238 D hypothetical protein 2813966..2814238 Escherichia coli str. K-12 substr. DH10B 6060095 YP_001731516.1 CDS kgtP NC_010473.1 2814235 2815533 R alpha-ketoglutarate transporter complement(2814235..2815533) Escherichia coli str. K-12 substr. DH10B 6060096 YP_001731517.1 CDS clpB NC_010473.1 2821387 2823960 R protein disaggregation chaperone complement(2821387..2823960) Escherichia coli str. K-12 substr. DH10B 6060330 YP_001731518.1 CDS yfiH NC_010473.1 2824090 2824821 R hypothetical protein complement(2824090..2824821) Escherichia coli str. K-12 substr. DH10B 6060795 YP_001731519.1 CDS rluD NC_010473.1 2824818 2825798 R responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D complement(2824818..2825798) Escherichia coli str. K-12 substr. DH10B 6060808 YP_001731520.1 CDS yfiO NC_010473.1 2825933 2826670 D with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 2825933..2826670 Escherichia coli str. K-12 substr. DH10B 6060810 YP_001731521.1 CDS yfiA NC_010473.1 2826941 2827282 D associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA 2826941..2827282 Escherichia coli str. K-12 substr. DH10B 6060815 YP_001731523.1 CDS pheA NC_010473.1 2827532 2828692 D catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 2827532..2828692 Escherichia coli str. K-12 substr. DH10B 6060836 YP_001731524.1 CDS tyrA NC_010473.1 2828735 2829856 R catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase complement(2828735..2829856) Escherichia coli str. K-12 substr. DH10B 6060839 YP_001731525.1 CDS aroF NC_010473.1 2829867 2830937 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(2829867..2830937) Escherichia coli str. K-12 substr. DH10B 6060851 YP_001731526.1 CDS yfiL NC_010473.1 2831147 2831512 D hypothetical protein 2831147..2831512 Escherichia coli str. K-12 substr. DH10B 6060853 YP_001731527.1 CDS yfiR NC_010473.1 2831662 2832180 D hypothetical protein 2831662..2832180 Escherichia coli str. K-12 substr. DH10B 6060855 YP_001731528.1 CDS yfiN NC_010473.1 2832170 2833396 D hypothetical protein 2832170..2833396 Escherichia coli str. K-12 substr. DH10B 6060856 YP_001731529.1 CDS yfiB NC_010473.1 2833412 2833894 D putative outer membrane lipoprotein 2833412..2833894 Escherichia coli str. K-12 substr. DH10B 6060857 YP_001731530.1 CDS rplS NC_010473.1 2833970 2834317 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(2833970..2834317) Escherichia coli str. K-12 substr. DH10B 6060858 YP_001731531.1 CDS trmD NC_010473.1 2834359 2835126 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(2834359..2835126) Escherichia coli str. K-12 substr. DH10B 6060859 YP_001731532.1 CDS rimM NC_010473.1 2835157 2835705 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(2835157..2835705) Escherichia coli str. K-12 substr. DH10B 6060884 YP_001731533.1 CDS rpsP NC_010473.1 2835724 2835972 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(2835724..2835972) Escherichia coli str. K-12 substr. DH10B 6060887 YP_001731534.1 CDS ffh NC_010473.1 2836221 2837582 R with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein complement(2836221..2837582) Escherichia coli str. K-12 substr. DH10B 6060891 YP_001731535.1 CDS yfjD NC_010473.1 2838561 2839847 D hypothetical protein 2838561..2839847 Escherichia coli str. K-12 substr. DH10B 6060894 YP_001731536.1 CDS grpE NC_010473.1 2839902 2840495 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(2839902..2840495) Escherichia coli str. K-12 substr. DH10B 6060900 YP_001731537.1 CDS ppnK NC_010473.1 2840618 2841496 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 2840618..2841496 Escherichia coli str. K-12 substr. DH10B 6060907 YP_001731538.1 CDS recN NC_010473.1 2841582 2843243 D recombination and repair protein 2841582..2843243 Escherichia coli str. K-12 substr. DH10B 6060914 YP_001731539.1 CDS smpA NC_010473.1 2843392 2843733 D hypothetical protein 2843392..2843733 Escherichia coli str. K-12 substr. DH10B 6060934 YP_001731540.1 CDS yfjF NC_010473.1 2843795 2844085 R hypothetical protein complement(2843795..2844085) Escherichia coli str. K-12 substr. DH10B 6060935 YP_001731541.1 CDS yfjG NC_010473.1 2844075 2844551 R hypothetical protein complement(2844075..2844551) Escherichia coli str. K-12 substr. DH10B 6060946 YP_001731542.1 CDS smpB NC_010473.1 2844683 2845165 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 2844683..2845165 Escherichia coli str. K-12 substr. DH10B 6060947 YP_001731543.1 CDS yfjH NC_010473.1 2847431 2848387 R CP4-57 prophage; hypothetical protein complement(2847431..2848387) Escherichia coli str. K-12 substr. DH10B 6060353 YP_001731544.1 CDS alpA NC_010473.1 2848431 2848643 D CP4-57 prophage; DNA-binding transcriptional activator 2848431..2848643 Escherichia coli str. K-12 substr. DH10B 6060961 YP_001731545.1 CDS yfjI NC_010473.1 2848772 2850181 D CP4-57 prophage; hypothetical protein 2848772..2850181 Escherichia coli str. K-12 substr. DH10B 6060962 YP_001731546.1 CDS yfjJ NC_010473.1 2850334 2850960 D CP4-57 prophage; hypothetical protein 2850334..2850960 Escherichia coli str. K-12 substr. DH10B 6060963 YP_001731547.1 CDS yfjK NC_010473.1 2851138 2853327 R CP4-57 prophage; protein complement(2851138..2853327) Escherichia coli str. K-12 substr. DH10B 6060970 YP_001731548.1 CDS yfjL NC_010473.1 2853324 2854940 R CP4-57 prophage; hypothetical protein complement(2853324..2854940) Escherichia coli str. K-12 substr. DH10B 6060971 YP_001731549.1 CDS yfjM NC_010473.1 2855300 2855563 R CP4-57 prophage; hypothetical protein complement(2855300..2855563) Escherichia coli str. K-12 substr. DH10B 6060991 YP_001731550.1 CDS yfjN NC_010473.1 2855705 2856778 D CP4-57 prophage; RNase LS 2855705..2856778 Escherichia coli str. K-12 substr. DH10B 6060992 YP_001731551.1 CDS yfjO NC_010473.1 2856771 2857142 D CP4-57 prophage; hypothetical protein 2856771..2857142 Escherichia coli str. K-12 substr. DH10B 6060995 YP_001731552.1 CDS yfjP NC_010473.1 2857497 2858360 D CP4-57 prophage; GTP-binding protein 2857497..2858360 Escherichia coli str. K-12 substr. DH10B 6060996 YP_001731553.1 CDS yfjQ NC_010473.1 2858452 2859273 D CP4-57 prophage; hypothetical protein 2858452..2859273 Escherichia coli str. K-12 substr. DH10B 6061007 YP_001731554.1 CDS yfjR NC_010473.1 2859490 2860191 D CP4-57 prophage; DNA-binding transcriptional regulator 2859490..2860191 Escherichia coli str. K-12 substr. DH10B 6061009 YP_001731555.1 CDS ypjK NC_010473.1 2860232 2860468 D CP4-57 prophage; inner membrane protein 2860232..2860468 Escherichia coli str. K-12 substr. DH10B 6061011 YP_001731556.1 CDS yfjS NC_010473.1 2860468 2860911 D CP4-57 prophage; hypothetical protein 2860468..2860911 Escherichia coli str. K-12 substr. DH10B 6061015 YP_001731557.1 CDS yfjT NC_010473.1 2860935 2861402 D CP4-57 prophage; hypothetical protein 2860935..2861402 Escherichia coli str. K-12 substr. DH10B 6061018 YP_001731558.1 CDS yfjU NC_010473.1 2861627 2861941 R CP4-57 prophage; protein complement(2861627..2861941) Escherichia coli str. K-12 substr. DH10B 6061031 YP_001731559.1 CDS ypjL NC_010473.1 2861954 2862472 R CP4-57 prophage; inner membrane protein complement(2861954..2862472) Escherichia coli str. K-12 substr. DH10B 6061039 YP_001731560.1 CDS yfjV NC_010473.1 2862623 2862823 R CP4-57 prophage; hypothetical protein complement(2862623..2862823) Escherichia coli str. K-12 substr. DH10B 6061048 YP_001731561.1 CDS yfjW NC_010473.1 2863105 2864808 D CP4-57 prophage; inner membrane protein 2863105..2864808 Escherichia coli str. K-12 substr. DH10B 6061058 YP_001731562.1 CDS yfjX NC_010473.1 2865706 2866164 D CP4-57 prophage; antirestriction protein 2865706..2866164 Escherichia coli str. K-12 substr. DH10B 6061062 YP_001731563.1 CDS yfjY NC_010473.1 2866173 2866655 D CP4-57 prophage; DNA repair protein 2866173..2866655 Escherichia coli str. K-12 substr. DH10B 6061069 YP_001731564.1 CDS ypjJ NC_010473.1 2866664 2866864 D hypothetical protein 2866664..2866864 Escherichia coli str. K-12 substr. DH10B 6061075 YP_001731565.1 CDS yfjZ NC_010473.1 2866902 2867219 D CP4-57 prophage; antitoxin of the YpjF-YfjZ toxin-antitoxin system 2866902..2867219 Escherichia coli str. K-12 substr. DH10B 6061082 YP_001731566.1 CDS ypjF NC_010473.1 2867240 2867569 D CP4-57 prophage; toxin of the YpjF-YfjZ toxin-antitoxin system 2867240..2867569 Escherichia coli str. K-12 substr. DH10B 6061088 YP_001731567.1 CDS ygaT NC_010473.1 2878772 2879749 D in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 2878772..2879749 Escherichia coli str. K-12 substr. DH10B 6061534 YP_001731568.1 CDS ygaF NC_010473.1 2879769 2881037 D catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 2879769..2881037 Escherichia coli str. K-12 substr. DH10B 6061109 YP_001731569.1 CDS gabT NC_010473.1 2882522 2883802 D catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 2882522..2883802 Escherichia coli str. K-12 substr. DH10B 6061113 YP_001731570.1 CDS gabP NC_010473.1 2884040 2885440 D gamma-aminobutyrate transporter 2884040..2885440 Escherichia coli str. K-12 substr. DH10B 6061128 YP_001731571.1 CDS csiR NC_010473.1 2885461 2886123 D regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 2885461..2886123 Escherichia coli str. K-12 substr. DH10B 6061132 YP_001731572.1 CDS ygaU NC_010473.1 2886124 2886573 R LysM domain/BON superfamily protein complement(2886124..2886573) Escherichia coli str. K-12 substr. DH10B 6061134 YP_001731573.1 CDS yqaE NC_010473.1 2886657 2886815 R hypothetical protein complement(2886657..2886815) Escherichia coli str. K-12 substr. DH10B 6061144 YP_001731574.1 CDS ygaV NC_010473.1 2886998 2887297 D DNA-binding transcriptional regulator 2886998..2887297 Escherichia coli str. K-12 substr. DH10B 6061152 YP_001731575.1 CDS ygaP NC_010473.1 2887307 2887831 D inner membrane protein with hydrolase activity 2887307..2887831 Escherichia coli str. K-12 substr. DH10B 6061154 YP_001731576.1 CDS stpA NC_010473.1 2887878 2888282 R DNA binding protein complement(2887878..2888282) Escherichia coli str. K-12 substr. DH10B 6061158 YP_001731577.1 CDS ygaW NC_010473.1 2888951 2889400 D inner membrane protein 2888951..2889400 Escherichia coli str. K-12 substr. DH10B 6061160 YP_001731578.1 CDS ygaC NC_010473.1 2889437 2889781 R hypothetical protein complement(2889437..2889781) Escherichia coli str. K-12 substr. DH10B 6061161 YP_001731579.1 CDS nrdH NC_010473.1 2890510 2890755 D glutaredoxin-like protein 2890510..2890755 Escherichia coli str. K-12 substr. DH10B 6061169 YP_001731580.1 CDS nrdI NC_010473.1 2890752 2891162 D protein that stimulates ribonucleotide reduction; in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 2890752..2891162 Escherichia coli str. K-12 substr. DH10B 6061171 YP_001731581.1 CDS nrdE NC_010473.1 2891135 2893279 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2891135..2893279 Escherichia coli str. K-12 substr. DH10B 6061178 YP_001731582.1 CDS nrdF NC_010473.1 2893289 2894248 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 2893289..2894248 Escherichia coli str. K-12 substr. DH10B 6061179 YP_001731583.1 CDS proW NC_010473.1 2896574 2897638 D with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 2896574..2897638 Escherichia coli str. K-12 substr. DH10B 6061182 YP_001731584.1 CDS proX NC_010473.1 2897696 2898688 D with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 2897696..2898688 Escherichia coli str. K-12 substr. DH10B 6061186 YP_001731585.1 CDS ygaZ NC_010473.1 2900181 2900918 D transporter 2900181..2900918 Escherichia coli str. K-12 substr. DH10B 6058950 YP_001731586.1 CDS ygaH NC_010473.1 2900908 2901243 D hypothetical protein 2900908..2901243 Escherichia coli str. K-12 substr. DH10B 6061196 YP_001731587.1 CDS emrA NC_010473.1 2901991 2903163 D multidrug efflux system 2901991..2903163 Escherichia coli str. K-12 substr. DH10B 6061199 YP_001731588.1 CDS emrB NC_010473.1 2903180 2904718 D multidrug efflux system protein 2903180..2904718 Escherichia coli str. K-12 substr. DH10B 6061206 YP_001731589.1 CDS luxS NC_010473.1 2904782 2905297 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(2904782..2905297) Escherichia coli str. K-12 substr. DH10B 6061207 YP_001731590.1 CDS gshA NC_010473.1 2905447 2907003 R involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase complement(2905447..2907003) Escherichia coli str. K-12 substr. DH10B 6060402 YP_001731591.1 CDS yqaA NC_010473.1 2907076 2907504 R inner membrane protein complement(2907076..2907504) Escherichia coli str. K-12 substr. DH10B 6061230 YP_001731592.1 CDS yqaB NC_010473.1 2907501 2908067 R YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase complement(2907501..2908067) Escherichia coli str. K-12 substr. DH10B 6061231 YP_001731593.1 CDS csrA NC_010473.1 2909525 2909710 R affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator complement(2909525..2909710) Escherichia coli str. K-12 substr. DH10B 6061929 YP_001731594.1 CDS alaS NC_010473.1 2909945 2912575 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(2909945..2912575) Escherichia coli str. K-12 substr. DH10B 6061256 YP_001731595.1 CDS recX NC_010473.1 2912703 2913203 R binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX complement(2912703..2913203) Escherichia coli str. K-12 substr. DH10B 6061279 YP_001731596.1 CDS ygaD NC_010473.1 2914413 2914910 R competence damage-inducible protein A complement(2914413..2914910) Escherichia coli str. K-12 substr. DH10B 6061285 YP_001731597.1 CDS mltB NC_010473.1 2915055 2916140 R membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B complement(2915055..2916140) Escherichia coli str. K-12 substr. DH10B 6061287 YP_001731598.1 CDS srlA NC_010473.1 2916396 2916959 D PTS system glucitol/sorbitol-specific transporter subunit IIC 2916396..2916959 Escherichia coli str. K-12 substr. DH10B 6061295 YP_001731599.1 CDS srlE NC_010473.1 2916956 2917915 D glucitol/sorbitol-specific enzyme IIB component of PTS 2916956..2917915 Escherichia coli str. K-12 substr. DH10B 6061298 YP_001731600.1 CDS srlB NC_010473.1 2917926 2918297 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucitol/sorbitol-specific transporter subunit IIA 2917926..2918297 Escherichia coli str. K-12 substr. DH10B 6061303 YP_001731601.1 CDS srlD NC_010473.1 2918301 2919080 D catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; sorbitol-6-phosphate dehydrogenase 2918301..2919080 Escherichia coli str. K-12 substr. DH10B 6061308 YP_001731602.1 CDS gutM NC_010473.1 2919185 2919544 D regulator for glucitol utilization; DNA-binding transcriptional activator GutM 2919185..2919544 Escherichia coli str. K-12 substr. DH10B 6061314 YP_001731603.1 CDS srlR NC_010473.1 2919611 2920384 D regulates genes involved in glucitol utilization; DNA-binding transcriptional repressor SrlR 2919611..2920384 Escherichia coli str. K-12 substr. DH10B 6061315 YP_001731604.1 CDS gutQ NC_010473.1 2920377 2921342 D catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 2920377..2921342 Escherichia coli str. K-12 substr. DH10B 6061326 YP_001731605.1 CDS norR NC_010473.1 2921339 2922853 R Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcriptional regulator complement(2921339..2922853) Escherichia coli str. K-12 substr. DH10B 6061332 YP_001731606.1 CDS norV NC_010473.1 2923040 2924479 D detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin 2923040..2924479 Escherichia coli str. K-12 substr. DH10B 6061334 YP_001731607.1 CDS norW NC_010473.1 2924476 2925609 D catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 2924476..2925609 Escherichia coli str. K-12 substr. DH10B 6061342 YP_001731608.1 CDS hypF NC_010473.1 2925737 2927989 R carbamoyl phosphate phosphatase and maturation protein for [NiFe] hydrogenases complement(2925737..2927989) Escherichia coli str. K-12 substr. DH10B 6061358 YP_001731609.1 CDS hydN NC_010473.1 2928142 2928669 R involved in electron transport from formate to hydrogen; electron transport protein HydN complement(2928142..2928669) Escherichia coli str. K-12 substr. DH10B 6061361 YP_001731610.1 CDS ascG NC_010473.1 2928818 2929831 R DNA-binding transcriptional repressor complement(2928818..2929831) Escherichia coli str. K-12 substr. DH10B 6061363 YP_001731611.1 CDS ascF NC_010473.1 2930088 2931545 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC 2930088..2931545 Escherichia coli str. K-12 substr. DH10B 6061377 YP_001731612.1 CDS ascB NC_010473.1 2931554 2932978 D cryptic 6-phospho-beta-glucosidase 2931554..2932978 Escherichia coli str. K-12 substr. DH10B 6061380 YP_001731613.1 CDS hycI NC_010473.1 2933137 2933607 R involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease complement(2933137..2933607) Escherichia coli str. K-12 substr. DH10B 6061389 YP_001731614.1 CDS hycH NC_010473.1 2933600 2934010 R protein required for maturation of hydrogenase 3; protein Hycprotein H complement(2933600..2934010) Escherichia coli str. K-12 substr. DH10B 6061392 YP_001731615.1 CDS hycG NC_010473.1 2934007 2934774 R hydrogenase 3 and formate hydrogenase complex, HycG subunit complement(2934007..2934774) Escherichia coli str. K-12 substr. DH10B 6061399 YP_001731616.1 CDS hycF NC_010473.1 2934774 2935316 R electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit complement(2934774..2935316) Escherichia coli str. K-12 substr. DH10B 6061413 YP_001731617.1 CDS hycE NC_010473.1 2935326 2937035 R hydrogenase 3, large subunit complement(2935326..2937035) Escherichia coli str. K-12 substr. DH10B 6061425 YP_001731618.1 CDS hycD NC_010473.1 2937053 2937976 R hydrogenase 3, membrane subunit complement(2937053..2937976) Escherichia coli str. K-12 substr. DH10B 6061439 YP_001731619.1 CDS hycC NC_010473.1 2937979 2939805 R catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 complement(2937979..2939805) Escherichia coli str. K-12 substr. DH10B 6061441 YP_001731620.1 CDS hycB NC_010473.1 2939802 2940413 R hydrogenase 3, Fe-S subunit complement(2939802..2940413) Escherichia coli str. K-12 substr. DH10B 6061445 YP_001731621.1 CDS hycA NC_010473.1 2940538 2940999 R regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA complement(2940538..2940999) Escherichia coli str. K-12 substr. DH10B 6061446 YP_001731622.1 CDS hypA NC_010473.1 2941211 2941561 D protein involved in nickel insertion into hydrogenases 3; plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 2941211..2941561 Escherichia coli str. K-12 substr. DH10B 6061460 YP_001731623.1 CDS hypB NC_010473.1 2941565 2942437 D GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 2941565..2942437 Escherichia coli str. K-12 substr. DH10B 6061463 YP_001731624.1 CDS hypC NC_010473.1 2942428 2942700 D protein required for maturation of hydrogenases 1 and 3; HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 2942428..2942700 Escherichia coli str. K-12 substr. DH10B 6061465 YP_001731625.1 CDS hypD NC_010473.1 2942700 2943821 D protein required for maturation of hydrogenases; hypothetical protein 2942700..2943821 Escherichia coli str. K-12 substr. DH10B 6061476 YP_001731626.1 CDS hypE NC_010473.1 2943860 2944828 D carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein 2943860..2944828 Escherichia coli str. K-12 substr. DH10B 6061480 YP_001731627.1 CDS fhlA NC_010473.1 2944902 2946980 D DNA-binding transcriptional activator 2944902..2946980 Escherichia coli str. K-12 substr. DH10B 6061481 YP_001731628.1 CDS ygbA NC_010473.1 2947017 2947370 R hypothetical protein complement(2947017..2947370) Escherichia coli str. K-12 substr. DH10B 6061484 YP_001731629.1 CDS mutS NC_010473.1 2947657 2950218 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 2947657..2950218 Escherichia coli str. K-12 substr. DH10B 6061488 YP_001731630.1 CDS pphB NC_010473.1 2950324 2950980 D serine/threonine-specific protein phosphatase 2 2950324..2950980 Escherichia coli str. K-12 substr. DH10B 6061503 YP_001731631.1 CDS ygbI NC_010473.1 2951031 2951828 R DNA-binding transcriptional regulator complement(2951031..2951828) Escherichia coli str. K-12 substr. DH10B 6061508 YP_001731632.1 CDS ygbJ NC_010473.1 2951994 2952902 D dehydrogenase 2951994..2952902 Escherichia coli str. K-12 substr. DH10B 6061513 YP_001731633.1 CDS ygbK NC_010473.1 2952899 2954065 D hypothetical protein 2952899..2954065 Escherichia coli str. K-12 substr. DH10B 6061515 YP_001731634.1 CDS ygbM NC_010473.1 2954800 2955576 D hypothetical protein 2954800..2955576 Escherichia coli str. K-12 substr. DH10B 6061523 YP_001731635.1 CDS ygbN NC_010473.1 2955665 2957029 D member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; inner membrane permease YgbN 2955665..2957029 Escherichia coli str. K-12 substr. DH10B 6061526 YP_001731636.1 CDS rpoS NC_010473.1 2957123 2958115 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS complement(2957123..2958115) Escherichia coli str. K-12 substr. DH10B 6061531 YP_001731637.1 CDS nlpD NC_010473.1 2958178 2959317 R outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD complement(2958178..2959317) Escherichia coli str. K-12 substr. DH10B 6058878 YP_001731638.1 CDS pcm NC_010473.1 2959457 2960083 R catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase complement(2959457..2960083) Escherichia coli str. K-12 substr. DH10B 6061536 YP_001731639.1 CDS surE NC_010473.1 2960077 2960838 R catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE complement(2960077..2960838) Escherichia coli str. K-12 substr. DH10B 6061537 YP_001731640.1 CDS truD NC_010473.1 2960819 2961868 R catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D complement(2960819..2961868) Escherichia coli str. K-12 substr. DH10B 6061547 YP_001731641.1 CDS ispF NC_010473.1 2961865 2962344 R catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(2961865..2962344) Escherichia coli str. K-12 substr. DH10B 6061551 YP_001731642.1 CDS ispD NC_010473.1 2962344 2963054 R 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(2962344..2963054) Escherichia coli str. K-12 substr. DH10B 6061553 YP_001731643.1 CDS ftsB NC_010473.1 2963073 2963384 R forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB complement(2963073..2963384) Escherichia coli str. K-12 substr. DH10B 6061554 YP_001731644.1 CDS ygbE NC_010473.1 2963578 2963901 R hypothetical protein complement(2963578..2963901) Escherichia coli str. K-12 substr. DH10B 6061560 YP_001731645.1 CDS cysC NC_010473.1 2963951 2964556 R converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase complement(2963951..2964556) Escherichia coli str. K-12 substr. DH10B 6061563 YP_001731646.1 CDS cysN NC_010473.1 2964556 2965983 R may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 complement(2964556..2965983) Escherichia coli str. K-12 substr. DH10B 6061564 YP_001731647.1 CDS cysD NC_010473.1 2965985 2966893 R with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 complement(2965985..2966893) Escherichia coli str. K-12 substr. DH10B 6061566 YP_001731648.1 CDS iap NC_010473.1 2967145 2968182 D catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase isozyme conversion aminopeptidase 2967145..2968182 Escherichia coli str. K-12 substr. DH10B 6061572 YP_001731649.1 CDS ygbF NC_010473.1 2969133 2969417 R hypothetical protein complement(2969133..2969417) Escherichia coli str. K-12 substr. DH10B 6062411 YP_001731650.1 CDS ygbT NC_010473.1 2969419 2970336 R hypothetical protein complement(2969419..2970336) Escherichia coli str. K-12 substr. DH10B 6061577 YP_001731651.1 CDS ygcH NC_010473.1 2970352 2970951 R hypothetical protein complement(2970352..2970951) Escherichia coli str. K-12 substr. DH10B 6061582 YP_001731652.1 CDS ygcI NC_010473.1 2970938 2971612 R hypothetical protein complement(2970938..2971612) Escherichia coli str. K-12 substr. DH10B 6061583 YP_001731653.1 CDS ygcJ NC_010473.1 2971615 2972706 R hypothetical protein complement(2971615..2972706) Escherichia coli str. K-12 substr. DH10B 6061588 YP_001731654.1 CDS ygcK NC_010473.1 2972719 2973201 R hypothetical protein complement(2972719..2973201) Escherichia coli str. K-12 substr. DH10B 6061590 YP_001731655.1 CDS ygcL NC_010473.1 2973194 2974702 R unknown function; in E. coli this protein is regulated by BaeR, a protein involved in resistance to novobiocin and deoxycholate; hypothetical protein complement(2973194..2974702) Escherichia coli str. K-12 substr. DH10B 6061595 YP_001731656.1 CDS ygcB NC_010473.1 2975117 2977783 R hypothetical protein complement(2975117..2977783) Escherichia coli str. K-12 substr. DH10B 6061596 YP_001731657.1 CDS cysH NC_010473.1 2978142 2978876 R catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase complement(2978142..2978876) Escherichia coli str. K-12 substr. DH10B 6061603 YP_001731658.1 CDS cysJ NC_010473.1 2980663 2982462 R catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha complement(2980663..2982462) Escherichia coli str. K-12 substr. DH10B 6061617 YP_001731659.1 CDS sscR NC_010473.1 2982778 2983143 D 6-pyruvoyl tetrahydrobiopterin synthase 2982778..2983143 Escherichia coli str. K-12 substr. DH10B 6061625 YP_001731660.1 CDS ygcN NC_010473.1 2983221 2984492 D oxidoreductase 2983221..2984492 Escherichia coli str. K-12 substr. DH10B 6061629 YP_001731661.1 CDS ygcO NC_010473.1 2984483 2984743 D 4Fe-4S binding protein 2984483..2984743 Escherichia coli str. K-12 substr. DH10B 6061641 YP_001731662.1 CDS ygcP NC_010473.1 2984760 2985335 D anti-terminator regulatory protein 2984760..2985335 Escherichia coli str. K-12 substr. DH10B 6061644 YP_001731663.1 CDS ygcQ NC_010473.1 2985483 2986343 R flavoprotein complement(2985483..2986343) Escherichia coli str. K-12 substr. DH10B 6061648 YP_001731664.1 CDS ygcR NC_010473.1 2986340 2987119 R flavoprotein complement(2986340..2987119) Escherichia coli str. K-12 substr. DH10B 6061652 YP_001731665.1 CDS ygcS NC_010473.1 2987097 2988434 R transporter complement(2987097..2988434) Escherichia coli str. K-12 substr. DH10B 6061654 YP_001731666.1 CDS ygcU NC_010473.1 2988528 2989982 R FAD containing dehydrogenase complement(2988528..2989982) Escherichia coli str. K-12 substr. DH10B 6061662 YP_001731667.1 CDS ygcW NC_010473.1 2990052 2990837 R deoxygluconate dehydrogenase complement(2990052..2990837) Escherichia coli str. K-12 substr. DH10B 6061686 YP_001731668.1 CDS yqcE NC_010473.1 2991156 2992433 D transporter 2991156..2992433 Escherichia coli str. K-12 substr. DH10B 6061691 YP_001731669.1 CDS ygcE NC_010473.1 2992460 2993938 D kinase 2992460..2993938 Escherichia coli str. K-12 substr. DH10B 6061697 YP_001731670.1 CDS ygcF NC_010473.1 2995311 2995982 R hypothetical protein complement(2995311..2995982) Escherichia coli str. K-12 substr. DH10B 6061701 YP_001731671.1 CDS eno NC_010473.1 2997207 2998505 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(2997207..2998505) Escherichia coli str. K-12 substr. DH10B 6061727 YP_001731672.1 CDS pyrG NC_010473.1 2998593 3000230 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(2998593..3000230) Escherichia coli str. K-12 substr. DH10B 6061747 YP_001731673.1 CDS mazG NC_010473.1 3000458 3001249 R functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase complement(3000458..3001249) Escherichia coli str. K-12 substr. DH10B 6061678 YP_001731674.1 CDS chpA NC_010473.1 3001320 3001655 R MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system; toxin ChpA complement(3001320..3001655) Escherichia coli str. K-12 substr. DH10B 6061751 YP_001731675.1 CDS chpR NC_010473.1 3001655 3001903 R part of the MazF-MazE toxin-antitoxin system; conteracts MazF; antitoxin MazE complement(3001655..3001903) Escherichia coli str. K-12 substr. DH10B 6061752 YP_001731676.1 CDS rumA NC_010473.1 3005599 3006900 R in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase complement(3005599..3006900) Escherichia coli str. K-12 substr. DH10B 6058839 YP_001731677.1 CDS barA NC_010473.1 3006957 3009713 D part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 3006957..3009713 Escherichia coli str. K-12 substr. DH10B 6061766 YP_001731678.1 CDS gudD NC_010473.1 3009945 3011285 R (D)-glucarate dehydratase 1 complement(3009945..3011285) Escherichia coli str. K-12 substr. DH10B 6061767 YP_001731679.1 CDS gudX NC_010473.1 3011306 3012646 R glucarate dehydratase complement(3011306..3012646) Escherichia coli str. K-12 substr. DH10B 6061782 YP_001731680.1 CDS gudP NC_010473.1 3012648 3014000 R D-glucarate transporter complement(3012648..3014000) Escherichia coli str. K-12 substr. DH10B 6061798 YP_001731681.1 CDS yqcA NC_010473.1 3014435 3014884 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(3014435..3014884) Escherichia coli str. K-12 substr. DH10B 6061817 YP_001731682.1 CDS truC NC_010473.1 3014902 3015684 R catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C complement(3014902..3015684) Escherichia coli str. K-12 substr. DH10B 6061825 YP_001731683.1 CDS yqcC NC_010473.1 3015684 3016013 R hypothetical protein complement(3015684..3016013) Escherichia coli str. K-12 substr. DH10B 6061829 YP_001731684.1 CDS syd NC_010473.1 3016635 3017180 R putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd complement(3016635..3017180) Escherichia coli str. K-12 substr. DH10B 6061866 YP_001731685.1 CDS queF NC_010473.1 3017248 3018096 D catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 3017248..3018096 Escherichia coli str. K-12 substr. DH10B 6061834 YP_001731686.1 CDS ygdH NC_010473.1 3018208 3019572 D hypothetical protein 3018208..3019572 Escherichia coli str. K-12 substr. DH10B 6061837 YP_001731687.1 CDS sdaC NC_010473.1 3020129 3021418 D serine transporter 3020129..3021418 Escherichia coli str. K-12 substr. DH10B 6061842 YP_001731688.1 CDS sdaB NC_010473.1 3021476 3022843 D L-serine deaminase II 3021476..3022843 Escherichia coli str. K-12 substr. DH10B 6061846 YP_001731689.1 CDS xni NC_010473.1 3022865 3023710 D has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 3022865..3023710 Escherichia coli str. K-12 substr. DH10B 6061848 YP_001731690.1 CDS fucO NC_010473.1 3023765 3024916 R L-1,2-propanediol oxidoreductase complement(3023765..3024916) Escherichia coli str. K-12 substr. DH10B 6061852 YP_001731691.1 CDS fucA NC_010473.1 3024941 3025588 R catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate; L-fuculose phosphate aldolase complement(3024941..3025588) Escherichia coli str. K-12 substr. DH10B 6061867 YP_001731692.1 CDS fucP NC_010473.1 3026135 3027451 D L-fucose transporter 3026135..3027451 Escherichia coli str. K-12 substr. DH10B 6061878 YP_001731693.1 CDS fucI NC_010473.1 3027484 3029259 D catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase 3027484..3029259 Escherichia coli str. K-12 substr. DH10B 6061885 YP_001731694.1 CDS fucK NC_010473.1 3029338 3030786 D L-fuculokinase 3029338..3030786 Escherichia coli str. K-12 substr. DH10B 6061897 YP_001731695.1 CDS fucU NC_010473.1 3030788 3031210 D L-fucose mutarotase 3030788..3031210 Escherichia coli str. K-12 substr. DH10B 6061901 YP_001731696.1 CDS fucR NC_010473.1 3031268 3031999 D regulates expression of genes involved in L-fucose utilization; DNA-binding transcriptional activator FucR 3031268..3031999 Escherichia coli str. K-12 substr. DH10B 6061902 YP_001731697.1 CDS ygdE NC_010473.1 3032043 3033143 R putative RNA 2'-O-ribose methyltransferase complement(3032043..3033143) Escherichia coli str. K-12 substr. DH10B 6061903 YP_001731698.1 CDS ygdD NC_010473.1 3033136 3033531 R hypothetical protein complement(3033136..3033531) Escherichia coli str. K-12 substr. DH10B 6061904 YP_001731699.1 CDS gcvA NC_010473.1 3033550 3034467 R Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA complement(3033550..3034467) Escherichia coli str. K-12 substr. DH10B 6061909 YP_001731700.1 CDS ygdI NC_010473.1 3034810 3035037 R hypothetical protein complement(3034810..3035037) Escherichia coli str. K-12 substr. DH10B 6061656 YP_001731701.1 CDS csdA NC_010473.1 3035229 3036434 D cysteine sulfinate desulfinase 3035229..3036434 Escherichia coli str. K-12 substr. DH10B 6058699 YP_001731702.1 CDS ygdK NC_010473.1 3036434 3036877 D Fe-S metabolism protein 3036434..3036877 Escherichia coli str. K-12 substr. DH10B 6061920 YP_001731703.1 CDS ygdL NC_010473.1 3036928 3037734 R hypothetical protein complement(3036928..3037734) Escherichia coli str. K-12 substr. DH10B 6061925 YP_001731704.1 CDS mltA NC_010473.1 3037973 3039070 R membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A complement(3037973..3039070) Escherichia coli str. K-12 substr. DH10B 6061927 YP_001731705.1 CDS amiC NC_010473.1 3039649 3040902 R N-acetylmuramoyl-L-alanine amidase complement(3039649..3040902) Escherichia coli str. K-12 substr. DH10B 6061252 YP_001731706.1 CDS argA NC_010473.1 3041134 3042465 D catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 3041134..3042465 Escherichia coli str. K-12 substr. DH10B 6061934 YP_001731707.1 CDS recD NC_010473.1 3042527 3044353 R helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha complement(3042527..3044353) Escherichia coli str. K-12 substr. DH10B 6061945 YP_001731708.1 CDS recB NC_010473.1 3044353 3047895 R helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta complement(3044353..3047895) Escherichia coli str. K-12 substr. DH10B 6061947 YP_001731709.1 CDS ptrA NC_010473.1 3047888 3050776 R protease III complement(3047888..3050776) Escherichia coli str. K-12 substr. DH10B 6061953 YP_001731710.1 CDS recC NC_010473.1 3050952 3054320 R catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma complement(3050952..3054320) Escherichia coli str. K-12 substr. DH10B 6061960 YP_001731711.1 CDS ppdC NC_010473.1 3054333 3054656 R hypothetical protein complement(3054333..3054656) Escherichia coli str. K-12 substr. DH10B 6061963 YP_001731712.1 CDS ygdB NC_010473.1 3054641 3055048 R hypothetical protein complement(3054641..3055048) Escherichia coli str. K-12 substr. DH10B 6061970 YP_001731713.1 CDS ppdB NC_010473.1 3055045 3055608 R hypothetical protein complement(3055045..3055608) Escherichia coli str. K-12 substr. DH10B 6061972 YP_001731714.1 CDS ppdA NC_010473.1 3055599 3056069 R hypothetical protein complement(3055599..3056069) Escherichia coli str. K-12 substr. DH10B 6061975 YP_001731715.1 CDS thyA NC_010473.1 3056253 3057047 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(3056253..3057047) Escherichia coli str. K-12 substr. DH10B 6061980 YP_001731716.1 CDS lgt NC_010473.1 3057054 3057929 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(3057054..3057929) Escherichia coli str. K-12 substr. DH10B 6061986 YP_001731717.1 CDS ptsP NC_010473.1 3058080 3060326 R member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain complement(3058080..3060326) Escherichia coli str. K-12 substr. DH10B 6061987 YP_001731718.1 CDS nudH NC_010473.1 3060339 3060869 R hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase complement(3060339..3060869) Escherichia coli str. K-12 substr. DH10B 6061999 YP_001731719.1 CDS mutH NC_010473.1 3061554 3062243 D MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 3061554..3062243 Escherichia coli str. K-12 substr. DH10B 6062009 YP_001731720.1 CDS ygdQ NC_010473.1 3062312 3063025 D inner membrane protein 3062312..3063025 Escherichia coli str. K-12 substr. DH10B 6062012 YP_001731721.1 CDS ygdR NC_010473.1 3063163 3063381 D hypothetical protein 3063163..3063381 Escherichia coli str. K-12 substr. DH10B 6062013 YP_001731722.1 CDS tas NC_010473.1 3063489 3064529 D complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; putative aldo-keto reductase 3063489..3064529 Escherichia coli str. K-12 substr. DH10B 6062025 YP_001731723.1 CDS ygeD NC_010473.1 3064561 3065754 R lysophospholipid transporter LplT complement(3064561..3065754) Escherichia coli str. K-12 substr. DH10B 6062030 YP_001731724.1 CDS aas NC_010473.1 3065747 3067906 R Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase complement(3065747..3067906) Escherichia coli str. K-12 substr. DH10B 6062031 YP_001731725.1 CDS galR NC_010473.1 3068491 3069522 D controls transcription of galETKM; DNA-binding transcriptional regulator GalR 3068491..3069522 Escherichia coli str. K-12 substr. DH10B 6060784 YP_001731726.1 CDS lysA NC_010473.1 3069529 3070791 R catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase complement(3069529..3070791) Escherichia coli str. K-12 substr. DH10B 6062035 YP_001731727.1 CDS lysR NC_010473.1 3070913 3071848 D activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; DNA-binding transcriptional regulator LysR 3070913..3071848 Escherichia coli str. K-12 substr. DH10B 6062036 YP_001731728.1 CDS ygeA NC_010473.1 3071835 3072527 R putative racemase complement(3071835..3072527) Escherichia coli str. K-12 substr. DH10B 6062037 YP_001731729.1 CDS araE NC_010473.1 3072656 3074074 R arabinose transporter complement(3072656..3074074) Escherichia coli str. K-12 substr. DH10B 6062041 YP_001731730.1 CDS kduD NC_010473.1 3074389 3075150 R catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase complement(3074389..3075150) Escherichia coli str. K-12 substr. DH10B 6062044 YP_001731731.1 CDS kduI NC_010473.1 3075180 3076016 R 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase complement(3075180..3076016) Escherichia coli str. K-12 substr. DH10B 6062046 YP_001731732.1 CDS yqeF NC_010473.1 3076303 3077484 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase complement(3076303..3077484) Escherichia coli str. K-12 substr. DH10B 6062051 YP_001731733.1 CDS yqeG NC_010473.1 3077739 3078968 D transporter 3077739..3078968 Escherichia coli str. K-12 substr. DH10B 6062053 YP_001731734.1 CDS yqeH NC_010473.1 3079428 3080060 D hypothetical protein 3079428..3080060 Escherichia coli str. K-12 substr. DH10B 6062054 YP_001731735.1 CDS yqeI NC_010473.1 3080394 3081203 D transcriptional regulator 3080394..3081203 Escherichia coli str. K-12 substr. DH10B 6062059 YP_001731736.1 CDS yqeJ NC_010473.1 3081196 3081678 D hypothetical protein 3081196..3081678 Escherichia coli str. K-12 substr. DH10B 6062065 YP_001731737.1 CDS yqeK NC_010473.1 3081827 3082252 R hypothetical protein complement(3081827..3082252) Escherichia coli str. K-12 substr. DH10B 6062069 YP_001731738.1 CDS ygeF NC_010473.1 3082446 3082892 D hypothetical protein 3082446..3082892 Escherichia coli str. K-12 substr. DH10B 6062071 YP_001731739.1 CDS ygeG NC_010473.1 3083160 3083651 D chaperone 3083160..3083651 Escherichia coli str. K-12 substr. DH10B 6062074 YP_001731740.1 CDS ygeH NC_010473.1 3083986 3085362 D transcriptional regulator 3083986..3085362 Escherichia coli str. K-12 substr. DH10B 6062081 YP_001731741.1 CDS ygeI NC_010473.1 3085530 3085748 D hypothetical protein 3085530..3085748 Escherichia coli str. K-12 substr. DH10B 6061297 YP_001731742.1 CDS ygeK NC_010473.1 3086352 3086795 R DNA-binding transcriptional regulator complement(3086352..3086795) Escherichia coli str. K-12 substr. DH10B 6059267 YP_001731743.1 CDS ygeL NC_010473.1 3086829 3086984 R hypothetical protein complement(3086829..3086984) Escherichia coli str. K-12 substr. DH10B 6062089 YP_001731744.1 CDS ygeM NC_010473.1 3087206 3087637 R hypothetical protein complement(3087206..3087637) Escherichia coli str. K-12 substr. DH10B 6062090 YP_001731745.1 CDS ygeO NC_010473.1 3087854 3088279 R hypothetical protein complement(3087854..3088279) Escherichia coli str. K-12 substr. DH10B 6062094 YP_001731746.1 CDS insD-4 NC_010473.1 3088264 3089169 R IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD complement(3088264..3089169) Escherichia coli str. K-12 substr. DH10B 6062095 YP_001731747.1 CDS insC-4 NC_010473.1 3089127 3089537 R IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein complement(3089127..3089537) Escherichia coli str. K-12 substr. DH10B 6062097 YP_001731748.1 CDS ygeR NC_010473.1 3091028 3091783 R TPR repeat-containing transcriptional regulator complement(3091028..3091783) Escherichia coli str. K-12 substr. DH10B 6059742 YP_001731749.1 CDS xdhA NC_010473.1 3092237 3094495 D putative molybdenum cofactor-binding protein; participates in purine salvage; xanthine dehydrogenase subunit XdhA 3092237..3094495 Escherichia coli str. K-12 substr. DH10B 6062105 YP_001731750.1 CDS xdhB NC_010473.1 3094506 3095384 D FAD-binding subunit; with XdhA and XdhC participates in purine salvage; xanthine dehydrogenase subunit XdhB 3094506..3095384 Escherichia coli str. K-12 substr. DH10B 6062111 YP_001731751.1 CDS xdhC NC_010473.1 3095381 3095860 D iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage; xanthine dehydrogenase subunit XdhC 3095381..3095860 Escherichia coli str. K-12 substr. DH10B 6062120 YP_001731752.1 CDS ygeV NC_010473.1 3095900 3097678 R DNA-binding transcriptional regulator complement(3095900..3097678) Escherichia coli str. K-12 substr. DH10B 6062129 YP_001731753.1 CDS ygeW NC_010473.1 3098154 3099344 D aspartate/ornithine carbamoyltransferase family protein 3098154..3099344 Escherichia coli str. K-12 substr. DH10B 6062146 YP_001731754.1 CDS ygeX NC_010473.1 3099402 3100598 D catalyzes the formation of pyruvate from 2,3-diaminopropionate; diaminopropionate ammonia-lyase 3099402..3100598 Escherichia coli str. K-12 substr. DH10B 6062151 YP_001731755.1 CDS ygeY NC_010473.1 3100656 3101867 D Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases; peptidase 3100656..3101867 Escherichia coli str. K-12 substr. DH10B 6062159 YP_001731756.1 CDS hyuA NC_010473.1 3101920 3103305 D catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 3101920..3103305 Escherichia coli str. K-12 substr. DH10B 6062165 YP_001731757.1 CDS yqeA NC_010473.1 3103353 3104285 D catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 3103353..3104285 Escherichia coli str. K-12 substr. DH10B 6062194 YP_001731758.1 CDS yqeB NC_010473.1 3104506 3106131 R hypothetical protein complement(3104506..3106131) Escherichia coli str. K-12 substr. DH10B 6062205 YP_001731759.1 CDS yqeC NC_010473.1 3106179 3106949 R hypothetical protein complement(3106179..3106949) Escherichia coli str. K-12 substr. DH10B 6062215 YP_001731760.1 CDS ygfJ NC_010473.1 3107052 3107630 D hypothetical protein 3107052..3107630 Escherichia coli str. K-12 substr. DH10B 6062219 YP_001731761.1 CDS ygfK NC_010473.1 3107952 3111050 D with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase; putative selenate reductase subunit YgfK 3107952..3111050 Escherichia coli str. K-12 substr. DH10B 6062234 YP_001731762.1 CDS ssnA NC_010473.1 3111053 3112381 D in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS; putative chlorohydrolase/aminohydrolase 3111053..3112381 Escherichia coli str. K-12 substr. DH10B 6062242 YP_001731763.1 CDS ygfM NC_010473.1 3112432 3113211 D with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain; putative selenate reductase subunit YgfM 3112432..3113211 Escherichia coli str. K-12 substr. DH10B 6062244 YP_001731764.1 CDS xdhD NC_010473.1 3113208 3116078 D with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration; putative selenate reductase subunit YgfN 3113208..3116078 Escherichia coli str. K-12 substr. DH10B 6062249 YP_001731765.1 CDS ygfO NC_010473.1 3116243 3117643 D transporter 3116243..3117643 Escherichia coli str. K-12 substr. DH10B 6062259 YP_001731766.1 CDS guaD NC_010473.1 3117658 3118977 D Catalyzes the deamination of guanine; guanine deaminase 3117658..3118977 Escherichia coli str. K-12 substr. DH10B 6062266 YP_001731767.1 CDS ygfQ NC_010473.1 3119013 3120380 D transporter 3119013..3120380 Escherichia coli str. K-12 substr. DH10B 6062286 YP_001731768.1 CDS ygfT NC_010473.1 3120904 3122823 R unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); putative oxidoreductase Fe-S binding subunit complement(3120904..3122823) Escherichia coli str. K-12 substr. DH10B 6062300 YP_001731769.1 CDS ygfU NC_010473.1 3123259 3124707 D transporter 3123259..3124707 Escherichia coli str. K-12 substr. DH10B 6062308 YP_001731770.1 CDS idi NC_010473.1 3124957 3125505 D catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 3124957..3125505 Escherichia coli str. K-12 substr. DH10B 6062310 YP_001731771.1 CDS lysS NC_010473.1 3125549 3127066 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(3125549..3127066) Escherichia coli str. K-12 substr. DH10B 6062324 YP_001731772.1 CDS prfB NC_010473.1 3127076 3128174 R recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 complement(join(3127076..3128098,3128100..3128174)) Escherichia coli str. K-12 substr. DH10B 6062325 YP_001731773.1 CDS recJ NC_010473.1 3128265 3129998 R 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ complement(3128265..3129998) Escherichia coli str. K-12 substr. DH10B 6062327 YP_001731774.1 CDS dsbC NC_010473.1 3130004 3130714 R DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC complement(3130004..3130714) Escherichia coli str. K-12 substr. DH10B 6062354 YP_001731775.1 CDS xerD NC_010473.1 3130739 3131635 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD complement(3130739..3131635) Escherichia coli str. K-12 substr. DH10B 6062359 YP_001731776.1 CDS fldB NC_010473.1 3131747 3132268 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 3131747..3132268 Escherichia coli str. K-12 substr. DH10B 6062362 YP_001731777.1 CDS ygfX NC_010473.1 3132308 3132715 R hypothetical protein complement(3132308..3132715) Escherichia coli str. K-12 substr. DH10B 6062367 YP_001731778.1 CDS ygfY NC_010473.1 3132696 3132962 R hypothetical protein complement(3132696..3132962) Escherichia coli str. K-12 substr. DH10B 6062393 YP_001731779.1 CDS ygfZ NC_010473.1 3133205 3134185 D physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; putative global regulator 3133205..3134185 Escherichia coli str. K-12 substr. DH10B 6062395 YP_001731780.1 CDS yqfA NC_010473.1 3134381 3135040 R oxidoreductase, inner membrane subunit complement(3134381..3135040) Escherichia coli str. K-12 substr. DH10B 6062396 YP_001731781.1 CDS yqfB NC_010473.1 3135204 3135515 R hypothetical protein complement(3135204..3135515) Escherichia coli str. K-12 substr. DH10B 6062398 YP_001731782.1 CDS bglA NC_010473.1 3135554 3136993 D 6-phospho-beta-glucosidase 3135554..3136993 Escherichia coli str. K-12 substr. DH10B 6062426 YP_001731783.1 CDS ygfF NC_010473.1 3137050 3137793 R hypothetical protein complement(3137050..3137793) Escherichia coli str. K-12 substr. DH10B 6062383 YP_001731784.1 CDS gcvP NC_010473.1 3138060 3140933 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase complement(3138060..3140933) Escherichia coli str. K-12 substr. DH10B 6059123 YP_001731785.1 CDS gcvH NC_010473.1 3141052 3141441 R part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H complement(3141052..3141441) Escherichia coli str. K-12 substr. DH10B 6059228 YP_001731786.1 CDS visC NC_010473.1 3143007 3144209 R hypothetical protein complement(3143007..3144209) Escherichia coli str. K-12 substr. DH10B 6059093 YP_001731787.1 CDS ubiH NC_010473.1 3144232 3145410 R Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase complement(3144232..3145410) Escherichia coli str. K-12 substr. DH10B 6059242 YP_001731788.1 CDS pepP NC_010473.1 3145407 3146732 R exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II complement(3145407..3146732) Escherichia coli str. K-12 substr. DH10B 6058726 YP_001731789.1 CDS ygfB NC_010473.1 3146758 3147336 R the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein complement(3146758..3147336) Escherichia coli str. K-12 substr. DH10B 6062394 YP_001731790.1 CDS zapA NC_010473.1 3147504 3147833 D protein that localizes to the cytokinetic ring; Z-ring-associated protein 3147504..3147833 Escherichia coli str. K-12 substr. DH10B 6058955 YP_001731791.1 CDS ygfA NC_010473.1 3148133 3148681 D ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function; putative ligase 3148133..3148681 Escherichia coli str. K-12 substr. DH10B 6058089 YP_001731792.1 CDS serA NC_010473.1 3149070 3150302 R catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase complement(3149070..3150302) Escherichia coli str. K-12 substr. DH10B 6059149 YP_001731793.1 CDS rpiA NC_010473.1 3150558 3151217 R Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A complement(3150558..3151217) Escherichia coli str. K-12 substr. DH10B 6060133 YP_001731794.1 CDS yqfE NC_010473.1 3151273 3151503 R hypothetical protein complement(3151273..3151503) Escherichia coli str. K-12 substr. DH10B 6059646 YP_001731795.1 CDS argP NC_010473.1 3151645 3152538 D specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 3151645..3152538 Escherichia coli str. K-12 substr. DH10B 6060214 YP_001731796.1 CDS argK NC_010473.1 3154879 3155874 D functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins; arginine/ornithine transport system ATPase 3154879..3155874 Escherichia coli str. K-12 substr. DH10B 6059230 YP_001731797.1 CDS ygfG NC_010473.1 3155885 3156670 D catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA; methylmalonyl-CoA decarboxylase 3155885..3156670 Escherichia coli str. K-12 substr. DH10B 6058991 YP_001731798.1 CDS ygfI NC_010473.1 3158169 3159065 R DNA-binding transcriptional regulator complement(3158169..3159065) Escherichia coli str. K-12 substr. DH10B 6059051 YP_001731799.1 CDS yggE NC_010473.1 3159232 3159972 R hypothetical protein complement(3159232..3159972) Escherichia coli str. K-12 substr. DH10B 6060433 YP_001731800.1 CDS argO NC_010473.1 3160065 3160700 R Involved in the export of arginine; arginine exporter protein complement(3160065..3160700) Escherichia coli str. K-12 substr. DH10B 6059222 YP_001731801.1 CDS mscS NC_010473.1 3160839 3161699 R participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS complement(3160839..3161699) Escherichia coli str. K-12 substr. DH10B 6058915 YP_001731802.1 CDS fbaA NC_010473.1 3162057 3163136 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase complement(3162057..3163136) Escherichia coli str. K-12 substr. DH10B 6059029 YP_001731803.1 CDS pgk NC_010473.1 3163351 3164514 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(3163351..3164514) Escherichia coli str. K-12 substr. DH10B 6062255 YP_001731804.1 CDS epd NC_010473.1 3164564 3165583 R NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase complement(3164564..3165583) Escherichia coli str. K-12 substr. DH10B 6059857 YP_001731805.1 CDS frcK NC_010473.1 3165868 3166581 R putative fructose transport system kinase complement(3165868..3166581) Escherichia coli str. K-12 substr. DH10B 6059854 YP_001731806.1 CDS yggD NC_010473.1 3166578 3167087 R putative DNA-binding transcriptional regulator complement(3166578..3167087) Escherichia coli str. K-12 substr. DH10B 6059855 YP_001731807.1 CDS yggF NC_010473.1 3167109 3168074 R fructose-1,6-bisphosphatase II-like protein complement(3167109..3168074) Escherichia coli str. K-12 substr. DH10B 6059856 YP_001731808.1 CDS yggP NC_010473.1 3168071 3169348 R dehydrogenase complement(3168071..3169348) Escherichia coli str. K-12 substr. DH10B 6062316 YP_001731809.1 CDS tktA NC_010473.1 3172735 3174726 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(3172735..3174726) Escherichia coli str. K-12 substr. DH10B 6059044 YP_001731810.1 CDS yggG NC_010473.1 3175004 3175762 D peptidase 3175004..3175762 Escherichia coli str. K-12 substr. DH10B 6062175 YP_001731811.1 CDS speB NC_010473.1 3175968 3176888 R catalyzes the formation of putrescine from agmatine; agmatinase complement(3175968..3176888) Escherichia coli str. K-12 substr. DH10B 6062294 YP_001731812.1 CDS speA NC_010473.1 3177026 3179002 R catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase complement(3177026..3179002) Escherichia coli str. K-12 substr. DH10B 6062390 YP_001731813.1 CDS yqgB NC_010473.1 3179011 3179157 R hypothetical protein complement(3179011..3179157) Escherichia coli str. K-12 substr. DH10B 6059850 YP_001731814.1 CDS yqgC NC_010473.1 3179278 3179493 D hypothetical protein 3179278..3179493 Escherichia coli str. K-12 substr. DH10B 6059849 YP_001731815.1 CDS yqgD NC_010473.1 3179490 3179741 R inner membrane protein complement(3179490..3179741) Escherichia coli str. K-12 substr. DH10B 6059848 YP_001731816.1 CDS metK NC_010473.1 3179797 3180951 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 3179797..3180951 Escherichia coli str. K-12 substr. DH10B 6059845 YP_001731817.1 CDS sprT NC_010473.1 3182846 3183343 D hypothetical protein 3182846..3183343 Escherichia coli str. K-12 substr. DH10B 6059846 YP_001731818.1 CDS yggJ NC_010473.1 3184225 3184956 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 3184225..3184956 Escherichia coli str. K-12 substr. DH10B 6058108 YP_001731819.1 CDS gshB NC_010473.1 3184969 3185919 D catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 3184969..3185919 Escherichia coli str. K-12 substr. DH10B 6059843 YP_001731820.1 CDS yqgE NC_010473.1 3186028 3186591 D hypothetical protein 3186028..3186591 Escherichia coli str. K-12 substr. DH10B 6059844 YP_001731821.1 CDS yqgF NC_010473.1 3186591 3187007 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 3186591..3187007 Escherichia coli str. K-12 substr. DH10B 6059841 YP_001731822.1 CDS yggR NC_010473.1 3187191 3188171 R transporter complement(3187191..3188171) Escherichia coli str. K-12 substr. DH10B 6059837 YP_001731823.1 CDS yggS NC_010473.1 3188189 3188893 D hypothetical protein 3188189..3188893 Escherichia coli str. K-12 substr. DH10B 6059840 YP_001731824.1 CDS yggT NC_010473.1 3188911 3189477 D inner membrane protein 3188911..3189477 Escherichia coli str. K-12 substr. DH10B 6058737 YP_001731825.1 CDS yggU NC_010473.1 3189474 3189764 D hypothetical protein 3189474..3189764 Escherichia coli str. K-12 substr. DH10B 6058805 YP_001731826.1 CDS yggV NC_010473.1 3189772 3190365 D HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 3189772..3190365 Escherichia coli str. K-12 substr. DH10B 6058814 YP_001731827.1 CDS yggW NC_010473.1 3190358 3191494 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3190358..3191494 Escherichia coli str. K-12 substr. DH10B 6058883 YP_001731828.1 CDS yggM NC_010473.1 3191649 3192656 R hypothetical protein complement(3191649..3192656) Escherichia coli str. K-12 substr. DH10B 6058960 YP_001731829.1 CDS ansB NC_010473.1 3192773 3193819 R catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II complement(3192773..3193819) Escherichia coli str. K-12 substr. DH10B 6059065 YP_001731830.1 CDS yggN NC_010473.1 3193995 3194714 R hypothetical protein complement(3193995..3194714) Escherichia coli str. K-12 substr. DH10B 6059124 YP_001731831.1 CDS yggL NC_010473.1 3194898 3195224 R hypothetical protein complement(3194898..3195224) Escherichia coli str. K-12 substr. DH10B 6059203 YP_001731832.1 CDS trmB NC_010473.1 3195224 3195943 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(3195224..3195943) Escherichia coli str. K-12 substr. DH10B 6059235 YP_001731833.1 CDS mutY NC_010473.1 3196104 3197156 D adenine DNA glycosylase 3196104..3197156 Escherichia coli str. K-12 substr. DH10B 6058798 YP_001731834.1 CDS yggX NC_010473.1 3197184 3197459 D protein that protects iron-sulfur proteins against oxidative damage; hypothetical protein 3197184..3197459 Escherichia coli str. K-12 substr. DH10B 6058989 YP_001731835.1 CDS mltC NC_010473.1 3197524 3198603 D Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 3197524..3198603 Escherichia coli str. K-12 substr. DH10B 6059287 YP_001731836.1 CDS pppA NC_010473.1 3203945 3204754 D bifunctional prepilin leader peptidase and methylase 3203945..3204754 Escherichia coli str. K-12 substr. DH10B 6059714 YP_001731837.1 CDS yghG NC_010473.1 3204820 3205230 D hypothetical protein 3204820..3205230 Escherichia coli str. K-12 substr. DH10B 6059717 YP_001731838.1 CDS yghF NC_010473.1 3205377 3206243 D part of the general (type II) secretion pathway (GSP), a signal sequence-dependent process responsible for protein export; involved in trans-location of exoproteins from the cytoplasm to the periplasm; putative type II secretion protein GspC 3205377..3206243 Escherichia coli str. K-12 substr. DH10B 6059998 YP_001731839.1 CDS yghD NC_010473.1 3207171 3207707 D putative general secretion pathway protein YghD 3207171..3207707 Escherichia coli str. K-12 substr. DH10B 6059317 YP_001731840.1 CDS yqgA NC_010473.1 3208037 3208744 R inner membrane protein complement(3208037..3208744) Escherichia coli str. K-12 substr. DH10B 6062348 YP_001731841.1 CDS speC NC_010473.1 3209142 3211277 D ornithine decarboxylase 3209142..3211277 Escherichia coli str. K-12 substr. DH10B 6059808 YP_001731842.1 CDS glcA NC_010473.1 3215364 3217046 R glycolate transporter complement(3215364..3217046) Escherichia coli str. K-12 substr. DH10B 6060403 YP_001731843.1 CDS glcB NC_010473.1 3217401 3219572 R catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G complement(3217401..3219572) Escherichia coli str. K-12 substr. DH10B 6059600 YP_001731844.1 CDS glcG NC_010473.1 3219594 3219998 R hypothetical protein complement(3219594..3219998) Escherichia coli str. K-12 substr. DH10B 6059409 YP_001731845.1 CDS glcF NC_010473.1 3220003 3221226 R glycolate oxidase iron-sulfur subunit complement(3220003..3221226) Escherichia coli str. K-12 substr. DH10B 6059170 YP_001731846.1 CDS glcE NC_010473.1 3221237 3222289 R glycolate oxidase FAD binding subunit complement(3221237..3222289) Escherichia coli str. K-12 substr. DH10B 6058982 YP_001731847.1 CDS glcD NC_010473.1 3222289 3223788 R glycolate oxidase subunit GlcD complement(3222289..3223788) Escherichia coli str. K-12 substr. DH10B 6058707 YP_001731848.1 CDS glcC NC_010473.1 3224039 3224803 D DNA-binding transcriptional regulator GlcC 3224039..3224803 Escherichia coli str. K-12 substr. DH10B 6058943 YP_001731849.1 CDS yghO NC_010473.1 3224810 3225982 R DNA-binding transcriptional regulator complement(3224810..3225982) Escherichia coli str. K-12 substr. DH10B 6058861 YP_001731850.1 CDS insH-9 NC_010473.1 3225945 3226961 D IS5 transposase and trans-activator 3225945..3226961 Escherichia coli str. K-12 substr. DH10B 6059250 YP_001731851.1 CDS yghQ NC_010473.1 3227108 3228175 R inner membrane protein complement(3227108..3228175) Escherichia coli str. K-12 substr. DH10B 6059609 YP_001731852.1 CDS yghR NC_010473.1 3228221 3228979 R nucleoside triphosphate hydrolase domain-containing protein complement(3228221..3228979) Escherichia coli str. K-12 substr. DH10B 6059733 YP_001731853.1 CDS yghS NC_010473.1 3229011 3229724 R nucleoside triphosphate hydrolase domain-containing protein complement(3229011..3229724) Escherichia coli str. K-12 substr. DH10B 6060421 YP_001731854.1 CDS yghT NC_010473.1 3229898 3230590 D nucleoside triphosphate hydrolase domain-containing protein 3229898..3230590 Escherichia coli str. K-12 substr. DH10B 6060448 YP_001731855.1 CDS pitB NC_010473.1 3230639 3232138 R phosphate transporter complement(3230639..3232138) Escherichia coli str. K-12 substr. DH10B 6059836 YP_001731856.1 CDS gss NC_010473.1 3232430 3234289 R catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase complement(3232430..3234289) Escherichia coli str. K-12 substr. DH10B 6058636 YP_001731857.1 CDS yghU NC_010473.1 3234494 3235360 D YghU; B2989; one of eight putative glutathione transferase proteins from E. coli; putative glutathione S-transferase YghU 3234494..3235360 Escherichia coli str. K-12 substr. DH10B 6060407 YP_001731858.1 CDS hybG NC_010473.1 3235483 3235731 R hydrogenase 2 accessory protein HypG complement(3235483..3235731) Escherichia coli str. K-12 substr. DH10B 6060185 YP_001731859.1 CDS hybF NC_010473.1 3235744 3236085 R plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF complement(3235744..3236085) Escherichia coli str. K-12 substr. DH10B 6059933 YP_001731860.1 CDS hybE NC_010473.1 3236078 3236566 R hydrogenase 2-specific chaperone complement(3236078..3236566) Escherichia coli str. K-12 substr. DH10B 6059763 YP_001731861.1 CDS hybD NC_010473.1 3236559 3237053 R protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase complement(3236559..3237053) Escherichia coli str. K-12 substr. DH10B 6059053 YP_001731862.1 CDS hybC NC_010473.1 3237053 3238756 R involved in hydrogen uptake; hydrogenase 2 large subunit complement(3237053..3238756) Escherichia coli str. K-12 substr. DH10B 6059621 YP_001731863.1 CDS hybB NC_010473.1 3238753 3239931 R HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; putative hydrogenase 2 b cytochrome subunit complement(3238753..3239931) Escherichia coli str. K-12 substr. DH10B 6059651 YP_001731864.1 CDS hybA NC_010473.1 3239921 3240907 R Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA complement(3239921..3240907) Escherichia coli str. K-12 substr. DH10B 6060220 YP_001731865.1 CDS hybO NC_010473.1 3240910 3242028 R involved in hydrogen uptake; hydrogenase 2 small subunit complement(3240910..3242028) Escherichia coli str. K-12 substr. DH10B 6059486 YP_001731866.1 CDS yghW NC_010473.1 3242217 3242504 R hypothetical protein complement(3242217..3242504) Escherichia coli str. K-12 substr. DH10B 6060830 YP_001731867.1 CDS yghZ NC_010473.1 3243664 3244704 D aldo-keto reductase 3243664..3244704 Escherichia coli str. K-12 substr. DH10B 6060886 YP_001731868.1 CDS yqhA NC_010473.1 3244744 3245238 R hypothetical protein complement(3244744..3245238) Escherichia coli str. K-12 substr. DH10B 6061166 YP_001731869.1 CDS yghA NC_010473.1 3245429 3246313 D oxidoreductase 3245429..3246313 Escherichia coli str. K-12 substr. DH10B 6060437 YP_001731870.1 CDS exbD NC_010473.1 3246585 3247010 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD complement(3246585..3247010) Escherichia coli str. K-12 substr. DH10B 6062154 YP_001731871.1 CDS exbB NC_010473.1 3247017 3247751 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB complement(3247017..3247751) Escherichia coli str. K-12 substr. DH10B 6060124 YP_001731872.1 CDS metC NC_010473.1 3248003 3249190 D catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3248003..3249190 Escherichia coli str. K-12 substr. DH10B 6060368 YP_001731873.1 CDS yghB NC_010473.1 3249330 3249989 D inner membrane protein 3249330..3249989 Escherichia coli str. K-12 substr. DH10B 6060297 YP_001731874.1 CDS yqhC NC_010473.1 3250029 3250985 R DNA-binding transcriptional regulator complement(3250029..3250985) Escherichia coli str. K-12 substr. DH10B 6060268 YP_001731875.1 CDS yqhD NC_010473.1 3251122 3252285 D alcohol dehydrogenase 3251122..3252285 Escherichia coli str. K-12 substr. DH10B 6060229 YP_001731876.1 CDS dkgA NC_010473.1 3252390 3253217 D methylglyoxal reductase/-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 3252390..3253217 Escherichia coli str. K-12 substr. DH10B 6060228 YP_001731877.1 CDS yqhG NC_010473.1 3253417 3254343 D hypothetical protein 3253417..3254343 Escherichia coli str. K-12 substr. DH10B 6060156 YP_001731878.1 CDS yqhH NC_010473.1 3254394 3254651 D putative outer membrane lipoprotein 3254394..3254651 Escherichia coli str. K-12 substr. DH10B 6059972 YP_001731879.1 CDS ygiQ NC_010473.1 3254694 3256913 R hypothetical protein complement(3254694..3256913) Escherichia coli str. K-12 substr. DH10B 6059932 YP_001731880.1 CDS sufI NC_010473.1 3257024 3258436 R repressor protein for FtsI complement(3257024..3258436) Escherichia coli str. K-12 substr. DH10B 6059776 YP_001731881.1 CDS plsC NC_010473.1 3258511 3259248 R 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(3258511..3259248) Escherichia coli str. K-12 substr. DH10B 6059749 YP_001731882.1 CDS parC NC_010473.1 3259482 3261740 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A complement(3259482..3261740) Escherichia coli str. K-12 substr. DH10B 6059861 YP_001731883.1 CDS ygiS NC_010473.1 3261878 3263485 R YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transport system; putative binding protein complement(3261878..3263485) Escherichia coli str. K-12 substr. DH10B 6059434 YP_001731884.1 CDS ygiT NC_010473.1 3263618 3264013 R DNA-binding transcriptional regulator complement(3263618..3264013) Escherichia coli str. K-12 substr. DH10B 6059627 YP_001731885.1 CDS mqsR NC_010473.1 3264015 3264311 R quorum-sensing regulator complement(3264015..3264311) Escherichia coli str. K-12 substr. DH10B 6059579 YP_001731886.1 CDS ygiV NC_010473.1 3264516 3264998 R transcriptional regulator complement(3264516..3264998) Escherichia coli str. K-12 substr. DH10B 6059388 YP_001731887.1 CDS ygiW NC_010473.1 3265051 3265443 R hypothetical protein complement(3265051..3265443) Escherichia coli str. K-12 substr. DH10B 6059466 YP_001731888.1 CDS qseB NC_010473.1 3265595 3266254 D response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 3265595..3266254 Escherichia coli str. K-12 substr. DH10B 6059403 YP_001731889.1 CDS qseC NC_010473.1 3266251 3267600 D sensor protein QseC 3266251..3267600 Escherichia coli str. K-12 substr. DH10B 6061989 YP_001731890.1 CDS ygiZ NC_010473.1 3267646 3267978 R inner membrane protein complement(3267646..3267978) Escherichia coli str. K-12 substr. DH10B 6058998 YP_001731891.1 CDS mdaB NC_010473.1 3268297 3268878 D NADPH quinone reductase 3268297..3268878 Escherichia coli str. K-12 substr. DH10B 6059365 YP_001731892.1 CDS ygiN NC_010473.1 3268909 3269223 D quinol monooxygenase 3268909..3269223 Escherichia coli str. K-12 substr. DH10B 6058853 YP_001731893.1 CDS parE NC_010473.1 3269271 3271163 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(3269271..3271163) Escherichia coli str. K-12 substr. DH10B 6059314 YP_001731894.1 CDS yqiA NC_010473.1 3271192 3271773 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YqiA complement(3271192..3271773) Escherichia coli str. K-12 substr. DH10B 6059272 YP_001731895.1 CDS cpdA NC_010473.1 3271773 3272600 R cyclic 3',5'-adenosine monophosphate phosphodiesterase complement(3271773..3272600) Escherichia coli str. K-12 substr. DH10B 6059315 YP_001731896.1 CDS yqiB NC_010473.1 3272625 3273047 R hypothetical protein complement(3272625..3273047) Escherichia coli str. K-12 substr. DH10B 6059243 YP_001731897.1 CDS nudF NC_010473.1 3273048 3273677 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase NudF complement(3273048..3273677) Escherichia coli str. K-12 substr. DH10B 6060275 YP_001731898.1 CDS tolC NC_010473.1 3273882 3275363 D trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 3273882..3275363 Escherichia coli str. K-12 substr. DH10B 6059239 YP_001731899.1 CDS ygiA NC_010473.1 3275363 3275623 D hypothetical protein 3275363..3275623 Escherichia coli str. K-12 substr. DH10B 6061704 YP_001731900.1 CDS ygiB NC_010473.1 3275607 3276182 D hypothetical protein 3275607..3276182 Escherichia coli str. K-12 substr. DH10B 6059186 YP_001731901.1 CDS ygiC NC_010473.1 3276188 3277348 D hypothetical protein 3276188..3277348 Escherichia coli str. K-12 substr. DH10B 6059117 YP_001731902.1 CDS ygiD NC_010473.1 3277386 3278174 R seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein complement(3277386..3278174) Escherichia coli str. K-12 substr. DH10B 6062019 YP_001731903.1 CDS zupT NC_010473.1 3278317 3279090 D zinc transporter ZupT 3278317..3279090 Escherichia coli str. K-12 substr. DH10B 6059071 YP_001731904.1 CDS ribB NC_010473.1 3279580 3280233 R DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase complement(3279580..3280233) Escherichia coli str. K-12 substr. DH10B 6060998 YP_001731905.1 CDS yqiC NC_010473.1 3280607 3280897 D hypothetical protein 3280607..3280897 Escherichia coli str. K-12 substr. DH10B 6058904 YP_001731906.1 CDS ygiL NC_010473.1 3281181 3281732 D putative fimbrial protein 3281181..3281732 Escherichia coli str. K-12 substr. DH10B 6058857 YP_001731907.1 CDS insC-5 NC_010473.1 3281909 3282319 D IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 3281909..3282319 Escherichia coli str. K-12 substr. DH10B 6058808 YP_001731908.1 CDS insD-5 NC_010473.1 3282277 3283182 D IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 3282277..3283182 Escherichia coli str. K-12 substr. DH10B 6058804 YP_001731909.1 CDS yqiG NC_010473.1 3283167 3285632 D outer membrane usher protein 3283167..3285632 Escherichia coli str. K-12 substr. DH10B 6058778 YP_001731910.1 CDS yqiH NC_010473.1 3285648 3286397 D periplasmic pilin chaperone 3285648..3286397 Escherichia coli str. K-12 substr. DH10B 6058753 YP_001731911.1 CDS yqiI NC_010473.1 3286399 3287463 D hypothetical protein 3286399..3287463 Escherichia coli str. K-12 substr. DH10B 6058721 YP_001731912.1 CDS glgS NC_010473.1 3287506 3287706 R Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS complement(3287506..3287706) Escherichia coli str. K-12 substr. DH10B 6060867 YP_001731913.1 CDS yqiJ NC_010473.1 3287975 3288604 D inner membrane protein 3287975..3288604 Escherichia coli str. K-12 substr. DH10B 6058712 YP_001731914.1 CDS yqiK NC_010473.1 3288631 3290292 D hypothetical protein 3288631..3290292 Escherichia coli str. K-12 substr. DH10B 6058718 YP_001731915.1 CDS rfaE NC_010473.1 3291087 3292520 R catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase complement(3291087..3292520) Escherichia coli str. K-12 substr. DH10B 6058470 YP_001731916.1 CDS glnE NC_010473.1 3292568 3295408 R catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase complement(3292568..3295408) Escherichia coli str. K-12 substr. DH10B 6059104 YP_001731917.1 CDS ygiF NC_010473.1 3295431 3296732 R adenylate cyclase complement(3295431..3296732) Escherichia coli str. K-12 substr. DH10B 6061930 YP_001731918.1 CDS htrG NC_010473.1 3296974 3297594 D putative signal transduction protein 3296974..3297594 Escherichia coli str. K-12 substr. DH10B 6059648 YP_001731919.1 CDS cca NC_010473.1 3297658 3298896 D catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 3297658..3298896 Escherichia coli str. K-12 substr. DH10B 6059369 YP_001731920.1 CDS bacA NC_010473.1 3299077 3299898 R BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase complement(3299077..3299898) Escherichia coli str. K-12 substr. DH10B 6060188 YP_001731921.1 CDS folB NC_010473.1 3299988 3300356 R catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase complement(3299988..3300356) Escherichia coli str. K-12 substr. DH10B 6059227 YP_001731922.1 CDS ygiH NC_010473.1 3300461 3301078 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY 3300461..3301078 Escherichia coli str. K-12 substr. DH10B 6062076 YP_001731923.1 CDS ygiP NC_010473.1 3301091 3302023 R activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol; transcriptional activator TtdR complement(3301091..3302023) Escherichia coli str. K-12 substr. DH10B 6060919 YP_001731924.1 CDS ttdA NC_010473.1 3302230 3303141 D Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 3302230..3303141 Escherichia coli str. K-12 substr. DH10B 6061071 YP_001731925.1 CDS ttdB NC_010473.1 3303138 3303743 D Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 3303138..3303743 Escherichia coli str. K-12 substr. DH10B 6062007 YP_001731926.1 CDS ygjE NC_010473.1 3303791 3305254 D tartrate:succinate antiporter 3303791..3305254 Escherichia coli str. K-12 substr. DH10B 6060896 YP_001731927.1 CDS ygjD NC_010473.1 3305297 3306310 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease complement(3305297..3306310) Escherichia coli str. K-12 substr. DH10B 6060505 YP_001731928.1 CDS rpsU NC_010473.1 3306548 3306763 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 3306548..3306763 Escherichia coli str. K-12 substr. DH10B 6060790 YP_001731929.1 CDS dnaG NC_010473.1 3306874 3308619 D synthesizes RNA primers at the replication forks; DNA primase 3306874..3308619 Escherichia coli str. K-12 substr. DH10B 6058823 YP_001731930.1 CDS rpoD NC_010473.1 3308814 3310655 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 3308814..3310655 Escherichia coli str. K-12 substr. DH10B 6062000 YP_001731931.1 CDS mug NC_010473.1 3310734 3311240 R G/U mismatch-specific DNA glycosylase complement(3310734..3311240) Escherichia coli str. K-12 substr. DH10B 6058812 YP_001731932.1 CDS yqjH NC_010473.1 3311494 3312258 R siderophore interacting protein complement(3311494..3312258) Escherichia coli str. K-12 substr. DH10B 6059513 YP_001731933.1 CDS yqjI NC_010473.1 3312546 3313169 D transcriptional regulator 3312546..3313169 Escherichia coli str. K-12 substr. DH10B 6061322 YP_001731934.1 CDS aer NC_010473.1 3313323 3314843 R fused signal transducer for aerotaxis sensory component; methyl accepting chemotaxis component complement(3313323..3314843) Escherichia coli str. K-12 substr. DH10B 6060341 YP_001731935.1 CDS ygjG NC_010473.1 3315234 3316640 D catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 3315234..3316640 Escherichia coli str. K-12 substr. DH10B 6061580 YP_001731936.1 CDS ygjH NC_010473.1 3316682 3317014 R hypothetical protein complement(3316682..3317014) Escherichia coli str. K-12 substr. DH10B 6062406 YP_001731937.1 CDS ebgR NC_010473.1 3317233 3318216 D DNA-binding transcriptional repressor EbgR 3317233..3318216 Escherichia coli str. K-12 substr. DH10B 6060803 YP_001731938.1 CDS ebgA NC_010473.1 3318400 3321492 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit alpha 3318400..3321492 Escherichia coli str. K-12 substr. DH10B 6061880 YP_001731939.1 CDS ebgC NC_010473.1 3321489 3321938 D in Escherichia coli this is the second beta-galactosidase system; cryptic beta-D-galactosidase subunit beta 3321489..3321938 Escherichia coli str. K-12 substr. DH10B 6061882 YP_001731940.1 CDS ygjI NC_010473.1 3322001 3323434 D transporter 3322001..3323434 Escherichia coli str. K-12 substr. DH10B 6061838 YP_001731941.1 CDS ygjJ NC_010473.1 3323568 3324638 D hypothetical protein 3323568..3324638 Escherichia coli str. K-12 substr. DH10B 6060920 YP_001731942.1 CDS ygjK NC_010473.1 3324655 3327006 D putative glycosyl hydrolase 3324655..3327006 Escherichia coli str. K-12 substr. DH10B 6061770 YP_001731943.1 CDS fadH NC_010473.1 3327432 3329450 D 2,4-dienoyl-CoA reductase 3327432..3329450 Escherichia coli str. K-12 substr. DH10B 6058764 YP_001731944.1 CDS ygjM NC_010473.1 3329495 3329911 R DNA-binding transcriptional regulator complement(3329495..3329911) Escherichia coli str. K-12 substr. DH10B 6061936 YP_001731945.1 CDS ygjN NC_010473.1 3329908 3330222 R hypothetical protein complement(3329908..3330222) Escherichia coli str. K-12 substr. DH10B 6060917 YP_001731946.1 CDS ygjO NC_010473.1 3330506 3331642 R methyltransferase small subunit complement(3330506..3331642) Escherichia coli str. K-12 substr. DH10B 6060967 YP_001731947.1 CDS ygjP NC_010473.1 3331727 3332230 D metal dependent hydrolase 3331727..3332230 Escherichia coli str. K-12 substr. DH10B 6060517 YP_001731948.1 CDS ygjQ NC_010473.1 3332307 3332999 D thioredoxin-like protein 3332307..3332999 Escherichia coli str. K-12 substr. DH10B 6060984 YP_001731949.1 CDS ygjR NC_010473.1 3333060 3334064 D NAD(P)-binding dehydrogenase 3333060..3334064 Escherichia coli str. K-12 substr. DH10B 6060994 YP_001731950.1 CDS alx NC_010473.1 3334347 3335312 D inner membrane protein, part of terminus 3334347..3335312 Escherichia coli str. K-12 substr. DH10B 6059283 YP_001731951.1 CDS sstT NC_010473.1 3335711 3336955 D involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 3335711..3336955 Escherichia coli str. K-12 substr. DH10B 6062011 YP_001731952.1 CDS ygjV NC_010473.1 3336960 3337511 R inner membrane protein complement(3336960..3337511) Escherichia coli str. K-12 substr. DH10B 6060980 YP_001731953.1 CDS uxaA NC_010473.1 3337594 3339081 R altronate hydrolase complement(3337594..3339081) Escherichia coli str. K-12 substr. DH10B 6061004 YP_001731954.1 CDS uxaC NC_010473.1 3339096 3340508 R catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase complement(3339096..3340508) Escherichia coli str. K-12 substr. DH10B 6062050 YP_001731955.1 CDS exuT NC_010473.1 3340871 3342289 D hexuronate transporter 3340871..3342289 Escherichia coli str. K-12 substr. DH10B 6061067 YP_001731956.1 CDS exuR NC_010473.1 3342419 3343195 D regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 3342419..3343195 Escherichia coli str. K-12 substr. DH10B 6061073 YP_001731957.1 CDS yqjA NC_010473.1 3343540 3344202 D inner membrane protein 3343540..3344202 Escherichia coli str. K-12 substr. DH10B 6060664 YP_001731958.1 CDS yqjB NC_010473.1 3344206 3344589 D hypothetical protein 3344206..3344589 Escherichia coli str. K-12 substr. DH10B 6062109 YP_001731959.1 CDS yqjC NC_010473.1 3344736 3345104 D hypothetical protein 3344736..3345104 Escherichia coli str. K-12 substr. DH10B 6060516 YP_001731960.1 CDS yqjD NC_010473.1 3345142 3345447 D hypothetical protein 3345142..3345447 Escherichia coli str. K-12 substr. DH10B 6060510 YP_001731961.1 CDS yqjE NC_010473.1 3345450 3345854 D inner membrane protein 3345450..3345854 Escherichia coli str. K-12 substr. DH10B 6060601 YP_001731962.1 CDS yqjK NC_010473.1 3345844 3346143 D hypothetical protein 3345844..3346143 Escherichia coli str. K-12 substr. DH10B 6060031 YP_001731963.1 CDS yqjF NC_010473.1 3346329 3346721 D quinol oxidase subunit 3346329..3346721 Escherichia coli str. K-12 substr. DH10B 6060671 YP_001731964.1 CDS yqjG NC_010473.1 3346791 3347777 D S-transferase 3346791..3347777 Escherichia coli str. K-12 substr. DH10B 6060600 YP_001731965.1 CDS yhaH NC_010473.1 3348071 3348436 D inner membrane protein 3348071..3348436 Escherichia coli str. K-12 substr. DH10B 6060690 YP_001731966.1 CDS yhaI NC_010473.1 3348678 3349034 D inner membrane protein 3348678..3349034 Escherichia coli str. K-12 substr. DH10B 6060807 YP_001731967.1 CDS yhaJ NC_010473.1 3349085 3349981 R DNA-binding transcriptional regulator complement(3349085..3349981) Escherichia coli str. K-12 substr. DH10B 6060739 YP_001731968.1 CDS yhaK NC_010473.1 3350086 3350787 D pirin-related protein 3350086..3350787 Escherichia coli str. K-12 substr. DH10B 6060874 YP_001731969.1 CDS yhaL NC_010473.1 3350810 3350974 D hypothetical protein 3350810..3350974 Escherichia coli str. K-12 substr. DH10B 6060882 YP_001731970.1 CDS yhaM NC_010473.1 3351108 3352418 R hypothetical protein complement(3351108..3352418) Escherichia coli str. K-12 substr. DH10B 6060895 YP_001731971.1 CDS yhaO NC_010473.1 3352446 3353714 R transporter complement(3352446..3353714) Escherichia coli str. K-12 substr. DH10B 6061061 YP_001731972.1 CDS tdcG NC_010473.1 3354052 3355416 R L-serine dehydratase 3 complement(3354052..3355416) Escherichia coli str. K-12 substr. DH10B 6061115 YP_001731973.1 CDS tdcF NC_010473.1 3355488 3355877 R hypothetical protein complement(3355488..3355877) Escherichia coli str. K-12 substr. DH10B 6061037 YP_001731974.1 CDS tdcE NC_010473.1 3355891 3358185 R pyruvate formate-lyase 4/2-ketobutyrate formate-lyase complement(3355891..3358185) Escherichia coli str. K-12 substr. DH10B 6061236 YP_001731975.1 CDS tdcD NC_010473.1 3358219 3359439 R catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism; propionate/acetate kinase complement(3358219..3359439) Escherichia coli str. K-12 substr. DH10B 6059823 YP_001731976.1 CDS tdcC NC_010473.1 3359453 3360784 R involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC complement(3359453..3360784) Escherichia coli str. K-12 substr. DH10B 6061826 YP_001731977.1 CDS tdcB NC_010473.1 3360806 3361795 R catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase complement(3360806..3361795) Escherichia coli str. K-12 substr. DH10B 6061793 YP_001731978.1 CDS tdcA NC_010473.1 3361894 3362832 R regulates the tdcABCDEFG operon which is involved in amino acid degradation; DNA-binding transcriptional activator TdcA complement(3361894..3362832) Escherichia coli str. K-12 substr. DH10B 6061941 YP_001731979.1 CDS tdcR NC_010473.1 3363147 3363365 D participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon; DNA-binding transcriptional activator TdcR 3363147..3363365 Escherichia coli str. K-12 substr. DH10B 6061957 YP_001731980.1 CDS yhaB NC_010473.1 3363621 3364160 D hypothetical protein 3363621..3364160 Escherichia coli str. K-12 substr. DH10B 6061921 YP_001731981.1 CDS yhaC NC_010473.1 3364182 3365369 D hypothetical protein 3364182..3365369 Escherichia coli str. K-12 substr. DH10B 6062122 YP_001731982.1 CDS garK NC_010473.1 3366392 3367618 R glycerate kinase complement(3366392..3367618) Escherichia coli str. K-12 substr. DH10B 6059015 YP_001731983.1 CDS garR NC_010473.1 3367634 3368524 R catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase complement(3367634..3368524) Escherichia coli str. K-12 substr. DH10B 6062429 YP_001731984.1 CDS garL NC_010473.1 3368554 3369324 R cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase complement(3368554..3369324) Escherichia coli str. K-12 substr. DH10B 6058659 YP_001731985.1 CDS garP NC_010473.1 3369340 3370674 R (D)-galactarate transporter complement(3369340..3370674) Escherichia coli str. K-12 substr. DH10B 6059838 YP_001731986.1 CDS garD NC_010473.1 3371049 3372620 D (D)-galactarate dehydrogenase 3371049..3372620 Escherichia coli str. K-12 substr. DH10B 6058623 YP_001731987.1 CDS sohA NC_010473.1 3372769 3373104 D SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation; putative regulator PrlF 3372769..3373104 Escherichia coli str. K-12 substr. DH10B 6060414 YP_001731988.1 CDS yhaV NC_010473.1 3373104 3373568 D hypothetical protein 3373104..3373568 Escherichia coli str. K-12 substr. DH10B 6059918 YP_001731989.1 CDS agaR NC_010473.1 3373623 3374432 R transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR complement(3373623..3374432) Escherichia coli str. K-12 substr. DH10B 6060218 YP_001731990.1 CDS kbaZ NC_010473.1 3374681 3375961 D tagatose 6-phosphate aldolase 1, kbaZ subunit 3374681..3375961 Escherichia coli str. K-12 substr. DH10B 6059873 YP_001731991.1 CDS agaV NC_010473.1 3375984 3376457 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3375984..3376457 Escherichia coli str. K-12 substr. DH10B 6059676 YP_001731992.1 CDS agaA NC_010473.1 3376889 3377392 D hypothetical protein 3376889..3377392 Escherichia coli str. K-12 substr. DH10B 6059370 YP_001731993.1 CDS agaS NC_010473.1 3377743 3378897 D tagatose-6-phosphate ketose/aldose isomerase 3377743..3378897 Escherichia coli str. K-12 substr. DH10B 6059618 YP_001731994.1 CDS kbaY NC_010473.1 3378910 3379770 D catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 3378910..3379770 Escherichia coli str. K-12 substr. DH10B 6060404 YP_001731995.1 CDS agaB NC_010473.1 3379937 3380413 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 3379937..3380413 Escherichia coli str. K-12 substr. DH10B 6059465 YP_001731996.1 CDS agaC NC_010473.1 3380452 3381255 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIC 3380452..3381255 Escherichia coli str. K-12 substr. DH10B 6060456 YP_001731997.1 CDS agaD NC_010473.1 3381245 3382036 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID 3381245..3382036 Escherichia coli str. K-12 substr. DH10B 6058770 YP_001731998.1 CDS agaI NC_010473.1 3382037 3382792 D galactosamine-6-phosphate isomerase 3382037..3382792 Escherichia coli str. K-12 substr. DH10B 6058676 YP_001731999.1 CDS yraH NC_010473.1 3383193 3383777 D fimbrial-like adhesin protein 3383193..3383777 Escherichia coli str. K-12 substr. DH10B 6060611 YP_001732000.1 CDS yraI NC_010473.1 3383857 3384552 D periplasmic pilin chaperone 3383857..3384552 Escherichia coli str. K-12 substr. DH10B 6058743 YP_001732001.1 CDS yraJ NC_010473.1 3384581 3387097 D outer membrane protein 3384581..3387097 Escherichia coli str. K-12 substr. DH10B 6060029 YP_001732002.1 CDS yraK NC_010473.1 3387108 3388199 D fimbrial-like adhesin protein 3387108..3388199 Escherichia coli str. K-12 substr. DH10B 6061016 YP_001732003.1 CDS yraL NC_010473.1 3388242 3389102 R methyltransferase complement(3388242..3389102) Escherichia coli str. K-12 substr. DH10B 6060933 YP_001732004.1 CDS yraM NC_010473.1 3389167 3391203 D hypothetical protein 3389167..3391203 Escherichia coli str. K-12 substr. DH10B 6058795 YP_001732005.1 CDS yraN NC_010473.1 3391161 3391556 D hypothetical protein 3391161..3391556 Escherichia coli str. K-12 substr. DH10B 6061281 YP_001732006.1 CDS diaA NC_010473.1 3391576 3392166 D Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 3391576..3392166 Escherichia coli str. K-12 substr. DH10B 6061155 YP_001732007.1 CDS yraP NC_010473.1 3392176 3392751 D hypothetical protein 3392176..3392751 Escherichia coli str. K-12 substr. DH10B 6061462 YP_001732008.1 CDS yraQ NC_010473.1 3392865 3393905 R permease complement(3392865..3393905) Escherichia coli str. K-12 substr. DH10B 6061600 YP_001732009.1 CDS yraR NC_010473.1 3393978 3394613 R nucleoside-diphosphate-sugar epimerase complement(3393978..3394613) Escherichia coli str. K-12 substr. DH10B 6059180 YP_001732010.1 CDS yhbO NC_010473.1 3394741 3395259 D intracellular protease 3394741..3395259 Escherichia coli str. K-12 substr. DH10B 6061855 YP_001732011.1 CDS yhbP NC_010473.1 3395239 3395682 R hypothetical protein complement(3395239..3395682) Escherichia coli str. K-12 substr. DH10B 6061907 YP_001732012.1 CDS yhbQ NC_010473.1 3395733 3396035 D GIY-YIG nuclease superfamily protein 3395733..3396035 Escherichia coli str. K-12 substr. DH10B 6062073 YP_001732013.1 CDS yhbS NC_010473.1 3396022 3396525 R acyltransferase complement(3396022..3396525) Escherichia coli str. K-12 substr. DH10B 6061969 YP_001732014.1 CDS yhbT NC_010473.1 3396519 3397043 R lipid carrier protein complement(3396519..3397043) Escherichia coli str. K-12 substr. DH10B 6062210 YP_001732015.1 CDS yhbU NC_010473.1 3397252 3398247 D peptidase (collagenase-like) 3397252..3398247 Escherichia coli str. K-12 substr. DH10B 6060299 YP_001732016.1 CDS yhbV NC_010473.1 3398256 3399134 D protease 3398256..3399134 Escherichia coli str. K-12 substr. DH10B 6060466 YP_001732017.1 CDS yhbW NC_010473.1 3399215 3400222 D hypothetical protein 3399215..3400222 Escherichia coli str. K-12 substr. DH10B 6060441 YP_001732018.1 CDS mtr NC_010473.1 3400340 3401584 R tryptophan transporter of high affinity; tryptophan permease complement(3400340..3401584) Escherichia coli str. K-12 substr. DH10B 6060128 YP_001732019.1 CDS deaD NC_010473.1 3401738 3403627 R participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD complement(3401738..3403627) Escherichia coli str. K-12 substr. DH10B 6060420 YP_001732020.1 CDS nlpI NC_010473.1 3403807 3404691 R lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI complement(3403807..3404691) Escherichia coli str. K-12 substr. DH10B 6060373 YP_001732021.1 CDS pnp NC_010473.1 3404800 3407004 R polynucleotide phosphorylase/polyadenylase complement(3404800..3407004) Escherichia coli str. K-12 substr. DH10B 6060347 YP_001732022.1 CDS rpsO NC_010473.1 3407182 3407451 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(3407182..3407451) Escherichia coli str. K-12 substr. DH10B 6062290 YP_001732023.1 CDS truB NC_010473.1 3407600 3408544 R catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(3407600..3408544) Escherichia coli str. K-12 substr. DH10B 6060312 YP_001732024.1 CDS rbfA NC_010473.1 3408544 3408945 R associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A complement(3408544..3408945) Escherichia coli str. K-12 substr. DH10B 6060256 YP_001732025.1 CDS infB NC_010473.1 3409109 3411781 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(3409109..3411781) Escherichia coli str. K-12 substr. DH10B 6060060 YP_001732026.1 CDS nusA NC_010473.1 3411806 3413293 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(3411806..3413293) Escherichia coli str. K-12 substr. DH10B 6060254 YP_001732027.1 CDS yhbC NC_010473.1 3413321 3413773 R in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein complement(3413321..3413773) Escherichia coli str. K-12 substr. DH10B 6060226 YP_001732028.1 CDS argG NC_010473.1 3414404 3415747 D catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 3414404..3415747 Escherichia coli str. K-12 substr. DH10B 6060897 YP_001732029.1 CDS yhbX NC_010473.1 3415755 3417380 R hydrolase, inner membrane complement(3415755..3417380) Escherichia coli str. K-12 substr. DH10B 6060010 YP_001732030.1 CDS secG NC_010473.1 3417940 3418272 R preprotein translocase subunit SecG complement(3417940..3418272) Escherichia coli str. K-12 substr. DH10B 6059703 YP_001732031.1 CDS glmM NC_010473.1 3418500 3419837 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(3418500..3419837) Escherichia coli str. K-12 substr. DH10B 6059875 YP_001732032.1 CDS folP NC_010473.1 3419830 3420678 R catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase complement(3419830..3420678) Escherichia coli str. K-12 substr. DH10B 6058533 YP_001732033.1 CDS hflB NC_010473.1 3420768 3422702 R inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease complement(3420768..3422702) Escherichia coli str. K-12 substr. DH10B 6059910 YP_001732034.1 CDS rrmJ NC_010473.1 3422802 3423431 R Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J complement(3422802..3423431) Escherichia coli str. K-12 substr. DH10B 6059785 YP_001732035.1 CDS yhbY NC_010473.1 3423557 3423850 D RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 3423557..3423850 Escherichia coli str. K-12 substr. DH10B 6059772 YP_001732036.1 CDS greA NC_010473.1 3424006 3424482 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(3424006..3424482) Escherichia coli str. K-12 substr. DH10B 6058137 YP_001732037.1 CDS dacB NC_010473.1 3424730 3426163 D penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 3424730..3426163 Escherichia coli str. K-12 substr. DH10B 6058226 YP_001732038.1 CDS obgE NC_010473.1 3426349 3427521 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(3426349..3427521) Escherichia coli str. K-12 substr. DH10B 6059698 YP_001732039.1 CDS yhbE NC_010473.1 3427537 3428502 R inner membrane protein complement(3427537..3428502) Escherichia coli str. K-12 substr. DH10B 6059731 YP_001732040.1 CDS rpmA NC_010473.1 3428629 3428886 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(3428629..3428886) Escherichia coli str. K-12 substr. DH10B 6061239 YP_001732041.1 CDS rplU NC_010473.1 3428907 3429218 R 50S ribosomal protein L21 complement(3428907..3429218) Escherichia coli str. K-12 substr. DH10B 6061349 YP_001732042.1 CDS ispB NC_010473.1 3429477 3430448 D octaprenyl diphosphate synthase 3429477..3430448 Escherichia coli str. K-12 substr. DH10B 6061444 YP_001732043.1 CDS sfsB NC_010473.1 3430676 3430954 D activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 3430676..3430954 Escherichia coli str. K-12 substr. DH10B 6061616 YP_001732044.1 CDS yrbA NC_010473.1 3432316 3432570 R DNA-binding transcriptional regulator complement(3432316..3432570) Escherichia coli str. K-12 substr. DH10B 6061591 YP_001732045.1 CDS yrbB NC_010473.1 3432730 3433023 R hypothetical protein complement(3432730..3433023) Escherichia coli str. K-12 substr. DH10B 6061664 YP_001732046.1 CDS yrbC NC_010473.1 3433023 3433658 R organic solvent ABC transporter complement(3433023..3433658) Escherichia coli str. K-12 substr. DH10B 6061722 YP_001732047.1 CDS yrbD NC_010473.1 3433677 3434228 R organic solvent ABC transporter complement(3433677..3434228) Escherichia coli str. K-12 substr. DH10B 6059771 YP_001732048.1 CDS yrbE NC_010473.1 3434233 3435015 R toluene ABC transporter membrane protein complement(3434233..3435015) Escherichia coli str. K-12 substr. DH10B 6059723 YP_001732049.1 CDS yrbF NC_010473.1 3435023 3435832 R ATP-binding subunit of a putative ABC toluene efflux transporter; putative ABC transporter ATP-binding protein YrbF complement(3435023..3435832) Escherichia coli str. K-12 substr. DH10B 6059696 YP_001732050.1 CDS yrbG NC_010473.1 3436042 3437019 D YrbG; inner membrane protein involved in cell envelope integrity; putative sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; putative calcium/sodium:proton antiporter 3436042..3437019 Escherichia coli str. K-12 substr. DH10B 6059629 YP_001732051.1 CDS kdsD NC_010473.1 3437033 3438019 D D-arabinose 5-phosphate isomerase 3437033..3438019 Escherichia coli str. K-12 substr. DH10B 6059640 YP_001732052.1 CDS kdsC NC_010473.1 3438040 3438606 D forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 3438040..3438606 Escherichia coli str. K-12 substr. DH10B 6059643 YP_001732053.1 CDS yrbK NC_010473.1 3438603 3439178 D hypothetical protein 3438603..3439178 Escherichia coli str. K-12 substr. DH10B 6062226 YP_001732054.1 CDS yhbN NC_010473.1 3439147 3439704 D LptA; periplasmic binding protein part of a putative ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 3439147..3439704 Escherichia coli str. K-12 substr. DH10B 6062126 YP_001732055.1 CDS yhbG NC_010473.1 3439711 3440436 D putative ABC transporter ATP-binding protein YhbG 3439711..3440436 Escherichia coli str. K-12 substr. DH10B 6062361 YP_001732056.1 CDS rpoN NC_010473.1 3440484 3441917 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 3440484..3441917 Escherichia coli str. K-12 substr. DH10B 6059391 YP_001732057.1 CDS hpf NC_010473.1 3441940 3442227 D YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; putative sigma(54) modulation protein 3441940..3442227 Escherichia coli str. K-12 substr. DH10B 6059493 YP_001732058.1 CDS ptsN NC_010473.1 3442345 3442836 D PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 3442345..3442836 Escherichia coli str. K-12 substr. DH10B 6059412 YP_001732059.1 CDS yhbJ NC_010473.1 3442882 3443736 D hypothetical protein 3442882..3443736 Escherichia coli str. K-12 substr. DH10B 6059601 YP_001732060.1 CDS npr NC_010473.1 3443733 3444005 D phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) 3443733..3444005 Escherichia coli str. K-12 substr. DH10B 6059308 YP_001732061.1 CDS yrbL NC_010473.1 3444219 3444851 D hypothetical protein 3444219..3444851 Escherichia coli str. K-12 substr. DH10B 6062005 YP_001732062.1 CDS mtgA NC_010473.1 3444848 3445576 R glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase complement(3444848..3445576) Escherichia coli str. K-12 substr. DH10B 6059432 YP_001732063.1 CDS elbB NC_010473.1 3445573 3446226 R isoprenoid biosynthesis protein with amidotransferase-like domain complement(3445573..3446226) Escherichia coli str. K-12 substr. DH10B 6059389 YP_001732064.1 CDS arcB NC_010473.1 3446456 3448792 R sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB complement(3446456..3448792) Escherichia coli str. K-12 substr. DH10B 6058702 YP_001732065.1 CDS yhcC NC_010473.1 3448888 3449817 R Fe-S oxidoreductase complement(3448888..3449817) Escherichia coli str. K-12 substr. DH10B 6059397 YP_001732066.1 CDS gltB NC_010473.1 3450399 3454952 D catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 3450399..3454952 Escherichia coli str. K-12 substr. DH10B 6059473 YP_001732067.1 CDS gltD NC_010473.1 3454965 3456383 D glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3454965..3456383 Escherichia coli str. K-12 substr. DH10B 6059526 YP_001732068.1 CDS gltF NC_010473.1 3456943 3457707 D hypothetical protein 3456943..3457707 Escherichia coli str. K-12 substr. DH10B 6061745 YP_001732069.1 CDS yhcA NC_010473.1 3457879 3458553 D member of the periplasmic pilus chaperone family of proteins; putative periplasmic chaperone protein 3457879..3458553 Escherichia coli str. K-12 substr. DH10B 6059353 YP_001732070.1 CDS yhcD NC_010473.1 3458574 3460955 D outer membrane protein 3458574..3460955 Escherichia coli str. K-12 substr. DH10B 6059310 YP_001732071.1 CDS insH-10 NC_010473.1 3461469 3462485 R IS5 transposase and trans-activator complement(3461469..3462485) Escherichia coli str. K-12 substr. DH10B 6061910 YP_001732072.1 CDS yhcF NC_010473.1 3462693 3463409 D transcriptional regulator 3462693..3463409 Escherichia coli str. K-12 substr. DH10B 6059335 YP_001732073.1 CDS yhcH NC_010473.1 3464781 3465245 R hypothetical protein complement(3464781..3465245) Escherichia coli str. K-12 substr. DH10B 6062410 YP_001732074.1 CDS nanK NC_010473.1 3465242 3466117 R catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase complement(3465242..3466117) Escherichia coli str. K-12 substr. DH10B 6059328 YP_001732075.1 CDS nanE NC_010473.1 3466114 3466803 R Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase complement(3466114..3466803) Escherichia coli str. K-12 substr. DH10B 6059330 YP_001732076.1 CDS nanT NC_010473.1 3466851 3468341 R putative sialic acid transporter complement(3466851..3468341) Escherichia coli str. K-12 substr. DH10B 6058549 YP_001732077.1 CDS nanA NC_010473.1 3468450 3469343 R catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase complement(3468450..3469343) Escherichia coli str. K-12 substr. DH10B 6061738 YP_001732078.1 CDS nanR NC_010473.1 3469465 3470256 R Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR complement(3469465..3470256) Escherichia coli str. K-12 substr. DH10B 6059247 YP_001732079.1 CDS dcuD NC_010473.1 3470636 3472003 D YhcL; uncharacterized member of the DcuC family of anaerobic dicarboxylate transporters; probable role in transport of carboxylates across the inner membrane from the periplasm; its encoding gene is not essential for growth and is probably cryptic; putative cryptic C4-dicarboxylate transporter DcuD 3470636..3472003 Escherichia coli str. K-12 substr. DH10B 6060531 YP_001732080.1 CDS sspB NC_010473.1 3472046 3472543 R ClpXP protease specificity-enhancing factor complement(3472046..3472543) Escherichia coli str. K-12 substr. DH10B 6059223 YP_001732081.1 CDS sspA NC_010473.1 3472549 3473187 R transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A complement(3472549..3473187) Escherichia coli str. K-12 substr. DH10B 6060941 YP_001732082.1 CDS rpsI NC_010473.1 3473582 3473974 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(3473582..3473974) Escherichia coli str. K-12 substr. DH10B 6059202 YP_001732083.1 CDS rplM NC_010473.1 3473990 3474418 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(3473990..3474418) Escherichia coli str. K-12 substr. DH10B 6059129 YP_001732084.1 CDS yhcM NC_010473.1 3474637 3475764 R hypothetical protein complement(3474637..3475764) Escherichia coli str. K-12 substr. DH10B 6059168 YP_001732085.1 CDS yhcB NC_010473.1 3475958 3476356 D cytochrome d ubiquinol oxidase subunit III 3475958..3476356 Escherichia coli str. K-12 substr. DH10B 6061311 YP_001732086.1 CDS degQ NC_010473.1 3476510 3477877 D serine endoprotease 3476510..3477877 Escherichia coli str. K-12 substr. DH10B 6059706 YP_001732087.1 CDS degS NC_010473.1 3477967 3479034 D serine endoprotease 3477967..3479034 Escherichia coli str. K-12 substr. DH10B 6062413 YP_001732088.1 CDS mdh NC_010473.1 3479097 3480035 R oxidizes malate to oxaloacetate; malate dehydrogenase complement(3479097..3480035) Escherichia coli str. K-12 substr. DH10B 6059112 YP_001732089.1 CDS argR NC_010473.1 3480470 3480940 D regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 3480470..3480940 Escherichia coli str. K-12 substr. DH10B 6059090 YP_001732090.1 CDS yhcN NC_010473.1 3481305 3481568 D hypothetical protein 3481305..3481568 Escherichia coli str. K-12 substr. DH10B 6061457 YP_001732091.1 CDS yhcO NC_010473.1 3481624 3481896 R barnase inhibitor complement(3481624..3481896) Escherichia coli str. K-12 substr. DH10B 6059045 YP_001732092.1 CDS aaeA NC_010473.1 3483961 3484893 R with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA complement(3483961..3484893) Escherichia coli str. K-12 substr. DH10B 6059066 YP_001732093.1 CDS aaeX NC_010473.1 3484901 3485104 R membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein complement(3484901..3485104) Escherichia coli str. K-12 substr. DH10B 6059034 YP_001732094.1 CDS aaeR NC_010473.1 3485287 3486216 D putative DNA-binding transcriptional regulator 3485287..3486216 Escherichia coli str. K-12 substr. DH10B 6059519 YP_001732095.1 CDS tldD NC_010473.1 3486350 3487795 R responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD complement(3486350..3487795) Escherichia coli str. K-12 substr. DH10B 6059006 YP_001732096.1 CDS yhdP NC_010473.1 3488225 3492025 R hypothetical protein complement(3488225..3492025) Escherichia coli str. K-12 substr. DH10B 6058962 YP_001732097.1 CDS rng NC_010473.1 3492093 3493562 R involved in the processing of the 5'end of 16S rRNA; ribonuclease G complement(3492093..3493562) Escherichia coli str. K-12 substr. DH10B 6061262 YP_001732098.1 CDS yhdE NC_010473.1 3493552 3494145 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(3493552..3494145) Escherichia coli str. K-12 substr. DH10B 6058930 YP_001732099.1 CDS mreD NC_010473.1 3494154 3494642 R part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD complement(3494154..3494642) Escherichia coli str. K-12 substr. DH10B 6059000 YP_001732100.1 CDS mreB NC_010473.1 3495811 3496854 R functions in MreBCD complex in some organisms; rod shape-determining protein MreB complement(3495811..3496854) Escherichia coli str. K-12 substr. DH10B 6058887 YP_001732101.1 CDS yhdA NC_010473.1 3497159 3499099 R regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD complement(3497159..3499099) Escherichia coli str. K-12 substr. DH10B 6059879 YP_001732102.1 CDS yhdH NC_010473.1 3499251 3500225 D oxidoreductase, Zn-dependent and NAD(P)-binding 3499251..3500225 Escherichia coli str. K-12 substr. DH10B 6058906 YP_001732103.1 CDS accB NC_010473.1 3501203 3501673 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3501203..3501673 Escherichia coli str. K-12 substr. DH10B 6058890 YP_001732104.1 CDS accC NC_010473.1 3501684 3503033 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 3501684..3503033 Escherichia coli str. K-12 substr. DH10B 6058863 YP_001732105.1 CDS yhdT NC_010473.1 3503142 3503384 D hypothetical protein 3503142..3503384 Escherichia coli str. K-12 substr. DH10B 6058850 YP_001732106.1 CDS panF NC_010473.1 3503374 3504825 D mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 3503374..3504825 Escherichia coli str. K-12 substr. DH10B 6058829 YP_001732107.1 CDS prmA NC_010473.1 3504837 3505718 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 3504837..3505718 Escherichia coli str. K-12 substr. DH10B 6058825 YP_001732108.1 CDS dusB NC_010473.1 3506047 3507012 D tRNA-dihydrouridine synthase B 3506047..3507012 Escherichia coli str. K-12 substr. DH10B 6060085 YP_001732109.1 CDS fis NC_010473.1 3507038 3507334 D Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 3507038..3507334 Escherichia coli str. K-12 substr. DH10B 6058830 YP_001732110.1 CDS yhdJ NC_010473.1 3507420 3508304 D putative methyltransferase 3507420..3508304 Escherichia coli str. K-12 substr. DH10B 6060943 YP_001732111.1 CDS yhdU NC_010473.1 3508388 3508567 D hypothetical protein 3508388..3508567 Escherichia coli str. K-12 substr. DH10B 6058799 YP_001732112.1 CDS envR NC_010473.1 3508570 3509232 R DNA-binding transcriptional regulator EnvR complement(3508570..3509232) Escherichia coli str. K-12 substr. DH10B 6058768 YP_001732113.1 CDS acrE NC_010473.1 3509631 3510788 D hypothetical protein 3509631..3510788 Escherichia coli str. K-12 substr. DH10B 6058793 YP_001732114.1 CDS acrF NC_010473.1 3510800 3513904 D multidrug efflux system protein 3510800..3513904 Escherichia coli str. K-12 substr. DH10B 6058714 YP_001732115.1 CDS yhdV NC_010473.1 3514157 3514378 D outer membrane protein 3514157..3514378 Escherichia coli str. K-12 substr. DH10B 6059438 YP_001732116.1 CDS yhdW NC_010473.1 3514916 3515833 D amino-acid ABC transporter periplasmic-binding protein 3514916..3515833 Escherichia coli str. K-12 substr. DH10B 6058747 YP_001732117.1 CDS yhdX NC_010473.1 3515901 3517082 D amino-acid ABC transporter membrane protein 3515901..3517082 Escherichia coli str. K-12 substr. DH10B 6060901 YP_001732118.1 CDS yhdY NC_010473.1 3517092 3518195 D amino-acid ABC transporter membrane protein 3517092..3518195 Escherichia coli str. K-12 substr. DH10B 6058728 YP_001732119.1 CDS yhdZ NC_010473.1 3518203 3518961 D amino-acid ABC transporter ATP-binding protein 3518203..3518961 Escherichia coli str. K-12 substr. DH10B 6060792 YP_001732120.1 CDS yrdA NC_010473.1 3525003 3525557 D hypothetical protein 3525003..3525557 Escherichia coli str. K-12 substr. DH10B 6061316 YP_001732121.1 CDS yrdB NC_010473.1 3525533 3525790 R hypothetical protein complement(3525533..3525790) Escherichia coli str. K-12 substr. DH10B 6061950 YP_001732122.1 CDS aroE NC_010473.1 3525787 3526605 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(3525787..3526605) Escherichia coli str. K-12 substr. DH10B 6061872 YP_001732123.1 CDS yrdC NC_010473.1 3526610 3527182 R RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; putative ribosome maturation factor complement(3526610..3527182) Escherichia coli str. K-12 substr. DH10B 6061541 YP_001732124.1 CDS yrdD NC_010473.1 3527187 3527729 R DNA topoisomerase complement(3527187..3527729) Escherichia coli str. K-12 substr. DH10B 6061055 YP_001732125.1 CDS smg NC_010473.1 3527758 3528231 R hypothetical protein complement(3527758..3528231) Escherichia coli str. K-12 substr. DH10B 6061978 YP_001732126.1 CDS smf NC_010473.1 3528203 3529327 R DNA protecting protein DprA complement(3528203..3529327) Escherichia coli str. K-12 substr. DH10B 6060918 YP_001732127.1 CDS def NC_010473.1 3529457 3529966 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 3529457..3529966 Escherichia coli str. K-12 substr. DH10B 6061433 YP_001732128.1 CDS fmt NC_010473.1 3529981 3530928 D modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 3529981..3530928 Escherichia coli str. K-12 substr. DH10B 6059727 YP_001732129.1 CDS rsmB NC_010473.1 3530974 3532263 D catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase B 3530974..3532263 Escherichia coli str. K-12 substr. DH10B 6059531 YP_001732130.1 CDS mscL NC_010473.1 3533791 3534201 D forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3533791..3534201 Escherichia coli str. K-12 substr. DH10B 6061307 YP_001732131.1 CDS yhdL NC_010473.1 3534198 3534416 R hypothetical protein complement(3534198..3534416) Escherichia coli str. K-12 substr. DH10B 6061819 YP_001732132.1 CDS zntR NC_010473.1 3534472 3534897 R mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator complement(3534472..3534897) Escherichia coli str. K-12 substr. DH10B 6061557 YP_001732133.1 CDS yhdN NC_010473.1 3534908 3535276 R hypothetical protein complement(3534908..3535276) Escherichia coli str. K-12 substr. DH10B 6061995 YP_001732134.1 CDS rplQ NC_010473.1 3535383 3535766 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(3535383..3535766) Escherichia coli str. K-12 substr. DH10B 6058843 YP_001732135.1 CDS rpoA NC_010473.1 3535807 3536796 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(3535807..3536796) Escherichia coli str. K-12 substr. DH10B 6060938 YP_001732136.1 CDS rpsD NC_010473.1 3536822 3537442 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(3536822..3537442) Escherichia coli str. K-12 substr. DH10B 6059087 YP_001732137.1 CDS rpsK NC_010473.1 3537476 3537865 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(3537476..3537865) Escherichia coli str. K-12 substr. DH10B 6061116 YP_001732138.1 CDS rpsM NC_010473.1 3537882 3538238 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(3537882..3538238) Escherichia coli str. K-12 substr. DH10B 6061558 YP_001732139.1 CDS rpmJ NC_010473.1 3538385 3538501 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 complement(3538385..3538501) Escherichia coli str. K-12 substr. DH10B 6062198 YP_001732140.1 CDS secY NC_010473.1 3538533 3539864 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(3538533..3539864) Escherichia coli str. K-12 substr. DH10B 6059858 YP_001732141.1 CDS rplO NC_010473.1 3539872 3540306 R late assembly protein; 50S ribosomal protein L15 complement(3539872..3540306) Escherichia coli str. K-12 substr. DH10B 6059573 YP_001732142.1 CDS rpmD NC_010473.1 3540310 3540489 R L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 complement(3540310..3540489) Escherichia coli str. K-12 substr. DH10B 6059786 YP_001732143.1 CDS rpsE NC_010473.1 3540493 3540996 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(3540493..3540996) Escherichia coli str. K-12 substr. DH10B 6059582 YP_001732144.1 CDS rplR NC_010473.1 3541011 3541364 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(3541011..3541364) Escherichia coli str. K-12 substr. DH10B 6059758 YP_001732145.1 CDS rplF NC_010473.1 3541374 3541907 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(3541374..3541907) Escherichia coli str. K-12 substr. DH10B 6058937 YP_001732146.1 CDS rpsH NC_010473.1 3541920 3542312 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(3541920..3542312) Escherichia coli str. K-12 substr. DH10B 6059437 YP_001732147.1 CDS rpsN NC_010473.1 3542346 3542651 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(3542346..3542651) Escherichia coli str. K-12 substr. DH10B 6059078 YP_001732148.1 CDS rplE NC_010473.1 3542666 3543205 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(3542666..3543205) Escherichia coli str. K-12 substr. DH10B 6059076 YP_001732149.1 CDS rplX NC_010473.1 3543220 3543534 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(3543220..3543534) Escherichia coli str. K-12 substr. DH10B 6058945 YP_001732150.1 CDS rplN NC_010473.1 3543545 3543916 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(3543545..3543916) Escherichia coli str. K-12 substr. DH10B 6059032 YP_001732151.1 CDS rpsQ NC_010473.1 3544081 3544335 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(3544081..3544335) Escherichia coli str. K-12 substr. DH10B 6058892 YP_001732152.1 CDS rpmC NC_010473.1 3544335 3544526 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(3544335..3544526) Escherichia coli str. K-12 substr. DH10B 6059352 YP_001732153.1 CDS rplP NC_010473.1 3544526 3544936 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(3544526..3544936) Escherichia coli str. K-12 substr. DH10B 6059491 YP_004770504.1 CDS ECDH10B_p1 NC_010473.1 3544949 3545650 R 30S ribosomal protein S3 complement(3544949..3545650) Escherichia coli str. K-12 substr. DH10B 11031905 YP_001732154.1 CDS rplV NC_010473.1 3545668 3546000 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(3545668..3546000) Escherichia coli str. K-12 substr. DH10B 6059022 YP_001732155.1 CDS rpsS NC_010473.1 3546015 3546293 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(3546015..3546293) Escherichia coli str. K-12 substr. DH10B 6058817 YP_001732156.1 CDS rplB NC_010473.1 3546310 3547131 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(3546310..3547131) Escherichia coli str. K-12 substr. DH10B 6061209 YP_001732157.1 CDS rplW NC_010473.1 3547149 3547451 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(3547149..3547451) Escherichia coli str. K-12 substr. DH10B 6058860 YP_001732158.1 CDS rplD NC_010473.1 3547448 3548053 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(3547448..3548053) Escherichia coli str. K-12 substr. DH10B 6058745 YP_001732159.1 CDS rplC NC_010473.1 3548064 3548693 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(3548064..3548693) Escherichia coli str. K-12 substr. DH10B 6059985 YP_001732160.1 CDS rpsJ NC_010473.1 3548726 3549037 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(3548726..3549037) Escherichia coli str. K-12 substr. DH10B 6058272 YP_001732161.1 CDS pioO NC_010473.1 3549275 3549694 R calcium-binding protein that may be required for the initiation of chromosome replication; chromosome replication protein PioO complement(3549275..3549694) Escherichia coli str. K-12 substr. DH10B 6060724 YP_001732162.1 CDS gspA NC_010473.1 3549696 3551165 R general secretory pathway component, cryptic complement(3549696..3551165) Escherichia coli str. K-12 substr. DH10B 6059183 YP_001732163.1 CDS gspC NC_010473.1 3551345 3552160 D general secretory pathway component, cryptic 3551345..3552160 Escherichia coli str. K-12 substr. DH10B 6062353 YP_001732164.1 CDS gspD NC_010473.1 3552144 3554096 D general secretory pathway component, cryptic 3552144..3554096 Escherichia coli str. K-12 substr. DH10B 6061717 YP_001732165.1 CDS gspE NC_010473.1 3554106 3555587 D general secretory pathway component, cryptic 3554106..3555587 Escherichia coli str. K-12 substr. DH10B 6060978 YP_001732166.1 CDS gspF NC_010473.1 3555584 3556780 D general secretory pathway component, cryptic 3555584..3556780 Escherichia coli str. K-12 substr. DH10B 6062144 YP_001732167.1 CDS gspG NC_010473.1 3556790 3557227 D pseudopilin, cryptic, general secretion pathway 3556790..3557227 Escherichia coli str. K-12 substr. DH10B 6060555 YP_001732168.1 CDS gspH NC_010473.1 3557235 3557744 D general secretory pathway component, cryptic 3557235..3557744 Escherichia coli str. K-12 substr. DH10B 6061104 YP_001732169.1 CDS gspI NC_010473.1 3557741 3558118 D general secretory pathway component, cryptic 3557741..3558118 Escherichia coli str. K-12 substr. DH10B 6061406 YP_001732170.1 CDS gspJ NC_010473.1 3558111 3558698 D general secretory pathway component, cryptic 3558111..3558698 Escherichia coli str. K-12 substr. DH10B 6061893 YP_001732171.1 CDS gspK NC_010473.1 3558691 3559674 D general secretory pathway component, cryptic 3558691..3559674 Escherichia coli str. K-12 substr. DH10B 6061780 YP_001732172.1 CDS gspL NC_010473.1 3559689 3560852 D general secretory pathway component, cryptic 3559689..3560852 Escherichia coli str. K-12 substr. DH10B 6059862 YP_001732173.1 CDS gspM NC_010473.1 3560849 3561310 D general secretory pathway component, cryptic 3560849..3561310 Escherichia coli str. K-12 substr. DH10B 6058075 YP_001732174.1 CDS gspO NC_010473.1 3561310 3561987 D bifunctional prepilin leader peptidase and methylase 3561310..3561987 Escherichia coli str. K-12 substr. DH10B 6060472 YP_001732175.1 CDS bfr NC_010473.1 3562016 3562492 R iron storage protein; bacterioferritin complement(3562016..3562492) Escherichia coli str. K-12 substr. DH10B 6060487 YP_001732176.1 CDS bfd NC_010473.1 3562564 3562758 R bacterioferritin-associated ferredoxin complement(3562564..3562758) Escherichia coli str. K-12 substr. DH10B 6061905 YP_001732177.1 CDS tufA NC_010473.1 3565912 3567096 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(3565912..3567096) Escherichia coli str. K-12 substr. DH10B 6061804 YP_001732178.1 CDS fusA NC_010473.1 3567167 3569281 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(3567167..3569281) Escherichia coli str. K-12 substr. DH10B 6058329 YP_001732179.1 CDS rpsG NC_010473.1 3569309 3569848 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(3569309..3569848) Escherichia coli str. K-12 substr. DH10B 6059670 YP_004770505.1 CDS ECDH10B_p2 NC_010473.1 3569945 3570319 R 30S ribosomal protein S12 complement(3569945..3570319) Escherichia coli str. K-12 substr. DH10B 11031906 YP_001732180.1 CDS yheL NC_010473.1 3570445 3570732 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB complement(3570445..3570732) Escherichia coli str. K-12 substr. DH10B 6059581 YP_001732181.1 CDS yheM NC_010473.1 3570740 3571099 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC complement(3570740..3571099) Escherichia coli str. K-12 substr. DH10B 6059423 YP_001732182.1 CDS yheN NC_010473.1 3571099 3571485 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD complement(3571099..3571485) Escherichia coli str. K-12 substr. DH10B 6059427 YP_001732183.1 CDS yheO NC_010473.1 3571485 3572207 R DNA-binding transcriptional regulator complement(3571485..3572207) Escherichia coli str. K-12 substr. DH10B 6059399 YP_001732184.1 CDS fkpA NC_010473.1 3572374 3573186 R rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase complement(3572374..3573186) Escherichia coli str. K-12 substr. DH10B 6059064 YP_001732185.1 CDS slyX NC_010473.1 3573407 3573625 D hypothetical protein 3573407..3573625 Escherichia coli str. K-12 substr. DH10B 6059232 YP_001732186.1 CDS slyD NC_010473.1 3573674 3574264 R rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase complement(3573674..3574264) Escherichia coli str. K-12 substr. DH10B 6059578 YP_001732187.1 CDS yheV NC_010473.1 3574359 3574559 R hypothetical protein complement(3574359..3574559) Escherichia coli str. K-12 substr. DH10B 6060251 YP_001732188.1 CDS kefB NC_010473.1 3574569 3576374 R involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB complement(3574569..3576374) Escherichia coli str. K-12 substr. DH10B 6060313 YP_001732189.1 CDS kefG NC_010473.1 3576374 3576928 R required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG complement(3576374..3576928) Escherichia coli str. K-12 substr. DH10B 6059138 YP_001732190.1 CDS yheS NC_010473.1 3577056 3578969 D putative ABC transporter ATP-binding protein 3577056..3578969 Escherichia coli str. K-12 substr. DH10B 6060384 YP_001732191.1 CDS yheT NC_010473.1 3578969 3579991 D putative hydrolase 3578969..3579991 Escherichia coli str. K-12 substr. DH10B 6058846 YP_001732192.1 CDS yheU NC_010473.1 3579985 3580203 D hypothetical protein 3579985..3580203 Escherichia coli str. K-12 substr. DH10B 6058739 YP_001732193.1 CDS prkB NC_010473.1 3580257 3581126 D phosphoribulokinase 3580257..3581126 Escherichia coli str. K-12 substr. DH10B 6060405 YP_001732194.1 CDS yhfA NC_010473.1 3581181 3581585 R hypothetical protein complement(3581181..3581585) Escherichia coli str. K-12 substr. DH10B 6058926 YP_001732195.1 CDS crp NC_010473.1 3581887 3582519 D complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 3581887..3582519 Escherichia coli str. K-12 substr. DH10B 6058677 YP_001732196.1 CDS yhfK NC_010473.1 3582558 3584660 D inner membrane protein 3582558..3584660 Escherichia coli str. K-12 substr. DH10B 6058992 YP_001732197.1 CDS argD NC_010473.1 3584727 3585947 R DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein complement(3584727..3585947) Escherichia coli str. K-12 substr. DH10B 6058980 YP_001732198.1 CDS pabA NC_010473.1 3586033 3586596 R aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II complement(3586033..3586596) Escherichia coli str. K-12 substr. DH10B 6059154 YP_001732199.1 CDS fic NC_010473.1 3586628 3587230 R cell filamentation protein Fic complement(3586628..3587230) Escherichia coli str. K-12 substr. DH10B 6059553 YP_001732200.1 CDS yhfG NC_010473.1 3587220 3587387 R hypothetical protein complement(3587220..3587387) Escherichia coli str. K-12 substr. DH10B 6059760 YP_001732201.1 CDS ppiA NC_010473.1 3587492 3588064 R peptidyl-prolyl cis-trans isomerase A complement(3587492..3588064) Escherichia coli str. K-12 substr. DH10B 6060439 YP_001732202.1 CDS tsgA NC_010473.1 3588335 3589516 D hypothetical protein 3588335..3589516 Escherichia coli str. K-12 substr. DH10B 6058644 YP_001732203.1 CDS nirB NC_010473.1 3589778 3592321 D nitrite reductase, large subunit, NAD(P)H-binding 3589778..3592321 Escherichia coli str. K-12 substr. DH10B 6058662 YP_001732204.1 CDS nirD NC_010473.1 3592318 3592644 D involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 3592318..3592644 Escherichia coli str. K-12 substr. DH10B 6059320 YP_001732205.1 CDS nirC NC_010473.1 3592770 3593576 D member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 3592770..3593576 Escherichia coli str. K-12 substr. DH10B 6059572 YP_001732206.1 CDS cysG NC_010473.1 3593595 3594968 D multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 3593595..3594968 Escherichia coli str. K-12 substr. DH10B 6059603 YP_001732207.1 CDS yhfL NC_010473.1 3595215 3595382 D secreted peptide 3595215..3595382 Escherichia coli str. K-12 substr. DH10B 6059815 YP_001732208.1 CDS frlA NC_010473.1 3595677 3597014 D inner membrane protein possibly involved in fructoselysine transport; member of the flr operon; putative fructoselysine transporter 3595677..3597014 Escherichia coli str. K-12 substr. DH10B 6059639 YP_001732209.1 CDS frlB NC_010473.1 3597035 3598057 D catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine; fructoselysine-6-P-deglycase 3597035..3598057 Escherichia coli str. K-12 substr. DH10B 6059657 YP_001732210.1 CDS frlC NC_010473.1 3598107 3598937 D YhfOP; YhfP; YhfO; FrlC; catalyzes the interconversion of fructoselysine and psicoselysine; fructoselysine 3-epimerase 3598107..3598937 Escherichia coli str. K-12 substr. DH10B 6059666 YP_001732211.1 CDS frlD NC_010473.1 3598934 3599719 D fructoselysine 6-kinase 3598934..3599719 Escherichia coli str. K-12 substr. DH10B 6059973 YP_001732212.1 CDS frlR NC_010473.1 3599819 3600550 D may act as a transcriptional regulator of a putative fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes; DNA-binding transcriptional regulator FrlR 3599819..3600550 Escherichia coli str. K-12 substr. DH10B 6060003 YP_001732213.1 CDS yhfS NC_010473.1 3600702 3601787 R hypothetical protein complement(3600702..3601787) Escherichia coli str. K-12 substr. DH10B 6062305 YP_001732214.1 CDS yhfT NC_010473.1 3601799 3603103 R inner membrane protein complement(3601799..3603103) Escherichia coli str. K-12 substr. DH10B 6061997 YP_001732215.1 CDS yhfU NC_010473.1 3603115 3603468 R hypothetical protein complement(3603115..3603468) Escherichia coli str. K-12 substr. DH10B 6061683 YP_001732216.1 CDS php NC_010473.1 3603479 3604357 R phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE); putative hydrolase complement(3603479..3604357) Escherichia coli str. K-12 substr. DH10B 6059017 YP_001732217.1 CDS yhfW NC_010473.1 3604354 3605580 R putative mutase complement(3604354..3605580) Escherichia coli str. K-12 substr. DH10B 6061261 YP_001732218.1 CDS yhfX NC_010473.1 3605580 3606743 R amino acid racemase complement(3605580..3606743) Escherichia coli str. K-12 substr. DH10B 6061107 YP_001732219.1 CDS yhfY NC_010473.1 3606827 3607189 R hypothetical protein complement(3606827..3607189) Escherichia coli str. K-12 substr. DH10B 6060985 YP_001732220.1 CDS yhfZ NC_010473.1 3607206 3608111 R hypothetical protein complement(3607206..3608111) Escherichia coli str. K-12 substr. DH10B 6060948 YP_001732221.1 CDS trpS NC_010473.1 3608401 3609405 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(3608401..3609405) Escherichia coli str. K-12 substr. DH10B 6060927 YP_001732222.1 CDS gph NC_010473.1 3609398 3610156 R catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase complement(3609398..3610156) Escherichia coli str. K-12 substr. DH10B 6060759 YP_001732223.1 CDS rpe NC_010473.1 3610149 3610826 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(3610149..3610826) Escherichia coli str. K-12 substr. DH10B 6060705 YP_001732224.1 CDS dam NC_010473.1 3610844 3611680 R DNA adenine methylase complement(3610844..3611680) Escherichia coli str. K-12 substr. DH10B 6060593 YP_001732225.1 CDS damX NC_010473.1 3611787 3613073 R hypothetical protein complement(3611787..3613073) Escherichia coli str. K-12 substr. DH10B 6059534 YP_001732226.1 CDS aroB NC_010473.1 3613165 3614253 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(3613165..3614253) Escherichia coli str. K-12 substr. DH10B 6058405 YP_001732227.1 CDS aroK NC_010473.1 3614310 3614831 R type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I complement(3614310..3614831) Escherichia coli str. K-12 substr. DH10B 6058602 YP_001732228.1 CDS hofQ NC_010473.1 3615232 3616470 R outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ complement(3615232..3616470) Escherichia coli str. K-12 substr. DH10B 6058164 YP_001732229.1 CDS yrfA NC_010473.1 3616382 3616786 R hypothetical protein complement(3616382..3616786) Escherichia coli str. K-12 substr. DH10B 6058372 YP_001732230.1 CDS yrfB NC_010473.1 3616776 3617216 R hypothetical protein complement(3616776..3617216) Escherichia coli str. K-12 substr. DH10B 6058460 YP_001732231.1 CDS yrfC NC_010473.1 3617200 3617739 R fimbrial assembly protein complement(3617200..3617739) Escherichia coli str. K-12 substr. DH10B 6058507 YP_001732232.1 CDS yrfD NC_010473.1 3617739 3618518 R pilus assembly protein complement(3617739..3618518) Escherichia coli str. K-12 substr. DH10B 6058167 YP_001732233.1 CDS mrcA NC_010473.1 3618638 3621190 D bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 3618638..3621190 Escherichia coli str. K-12 substr. DH10B 6060462 YP_001732234.1 CDS nudE NC_010473.1 3621356 3621916 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE complement(3621356..3621916) Escherichia coli str. K-12 substr. DH10B 6059292 YP_001732235.1 CDS yrfF NC_010473.1 3622236 3624371 D inner membrane protein 3622236..3624371 Escherichia coli str. K-12 substr. DH10B 6059286 YP_001732236.1 CDS yrfG NC_010473.1 3624436 3625104 D hydrolase 3624436..3625104 Escherichia coli str. K-12 substr. DH10B 6059623 YP_001732237.1 CDS hslR NC_010473.1 3625115 3625516 D ribosome-associated heat shock protein Hsp15 3625115..3625516 Escherichia coli str. K-12 substr. DH10B 6059683 YP_001732238.1 CDS hslO NC_010473.1 3625541 3626419 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 3625541..3626419 Escherichia coli str. K-12 substr. DH10B 6058587 YP_001732239.1 CDS yhgE NC_010473.1 3626482 3628206 R inner membrane protein complement(3626482..3628206) Escherichia coli str. K-12 substr. DH10B 6062196 YP_001732240.1 CDS pck NC_010473.1 3628585 3630207 D PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 3628585..3630207 Escherichia coli str. K-12 substr. DH10B 6062153 YP_001732241.1 CDS envZ NC_010473.1 3630283 3631635 R membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein complement(3630283..3631635) Escherichia coli str. K-12 substr. DH10B 6062092 YP_001732242.1 CDS ompR NC_010473.1 3631632 3632351 R part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator complement(3631632..3632351) Escherichia coli str. K-12 substr. DH10B 6062072 YP_001732243.1 CDS greB NC_010473.1 3632579 3633055 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 3632579..3633055 Escherichia coli str. K-12 substr. DH10B 6061973 YP_001732244.1 CDS yhgF NC_010473.1 3633152 3635473 D transcriptional accessory protein 3633152..3635473 Escherichia coli str. K-12 substr. DH10B 6061974 YP_001732245.1 CDS feoA NC_010473.1 3635930 3636157 D ferrous iron transport protein A 3635930..3636157 Escherichia coli str. K-12 substr. DH10B 6061832 YP_001732246.1 CDS feoB NC_010473.1 3636174 3638495 D cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 3636174..3638495 Escherichia coli str. K-12 substr. DH10B 6061692 YP_001732247.1 CDS yhgG NC_010473.1 3638495 3638731 D DNA-binding transcriptional regulator 3638495..3638731 Escherichia coli str. K-12 substr. DH10B 6061706 YP_001732248.1 CDS bioH NC_010473.1 3639841 3640611 R Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH complement(3639841..3640611) Escherichia coli str. K-12 substr. DH10B 6061636 YP_001732249.1 CDS gntX NC_010473.1 3640649 3641332 D involved in high-affinity gluconate transport; gluconate periplasmic binding protein 3640649..3641332 Escherichia coli str. K-12 substr. DH10B 6061614 YP_001732250.1 CDS gntY NC_010473.1 3641391 3641966 D cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; putative DNA uptake protein 3641391..3641966 Escherichia coli str. K-12 substr. DH10B 6061539 YP_001732251.1 CDS gntT NC_010473.1 3642326 3643642 D gluconate transporter, high-affinity GNT I system 3642326..3643642 Escherichia coli str. K-12 substr. DH10B 6061461 YP_001732252.1 CDS malQ NC_010473.1 3643753 3645837 R amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase complement(3643753..3645837) Escherichia coli str. K-12 substr. DH10B 6061510 YP_001732253.1 CDS malP NC_010473.1 3645847 3648240 R maltodextrin phosphorylase complement(3645847..3648240) Escherichia coli str. K-12 substr. DH10B 6061487 YP_001732254.1 CDS malT NC_010473.1 3648852 3651557 D Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 3648852..3651557 Escherichia coli str. K-12 substr. DH10B 6061359 YP_001732255.1 CDS rtcA NC_010473.1 3651600 3652616 R catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase complement(3651600..3652616) Escherichia coli str. K-12 substr. DH10B 6061384 YP_001732256.1 CDS rtcB NC_010473.1 3652620 3653846 R hypothetical protein complement(3652620..3653846) Escherichia coli str. K-12 substr. DH10B 6061312 YP_001732257.1 CDS rtcR NC_010473.1 3654035 3655633 D sigma 54-dependent transcriptional regulator of rtcBA expression 3654035..3655633 Escherichia coli str. K-12 substr. DH10B 6061333 YP_001732258.1 CDS glpR NC_010473.1 3655615 3656373 R represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR complement(3655615..3656373) Escherichia coli str. K-12 substr. DH10B 6061191 YP_001732259.1 CDS glpG NC_010473.1 3656390 3657220 R protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG complement(3656390..3657220) Escherichia coli str. K-12 substr. DH10B 6061251 YP_001732260.1 CDS glpE NC_010473.1 3657265 3657591 R belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase complement(3657265..3657591) Escherichia coli str. K-12 substr. DH10B 6061078 YP_001732261.1 CDS glpD NC_010473.1 3657781 3659286 D in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 3657781..3659286 Escherichia coli str. K-12 substr. DH10B 6061051 YP_001732262.1 CDS yzgL NC_010473.1 3659492 3659773 R hypothetical protein complement(3659492..3659773) Escherichia coli str. K-12 substr. DH10B 6061043 YP_001732263.1 CDS glgP NC_010473.1 3659902 3662349 R glycogen phosphorylase complement(3659902..3662349) Escherichia coli str. K-12 substr. DH10B 6061049 YP_001732264.1 CDS glgA NC_010473.1 3662368 3663801 R catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase complement(3662368..3663801) Escherichia coli str. K-12 substr. DH10B 6060955 YP_001732265.1 CDS glgC NC_010473.1 3663801 3665096 R catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase complement(3663801..3665096) Escherichia coli str. K-12 substr. DH10B 6060987 YP_001732266.1 CDS glgX NC_010473.1 3665114 3667087 R catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching protein complement(3665114..3667087) Escherichia coli str. K-12 substr. DH10B 6060912 YP_001732267.1 CDS glgB NC_010473.1 3667084 3669270 R catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein complement(3667084..3669270) Escherichia coli str. K-12 substr. DH10B 6060898 YP_001732268.1 CDS asd NC_010473.1 3669543 3670646 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(3669543..3670646) Escherichia coli str. K-12 substr. DH10B 6060816 YP_001732269.1 CDS yhgN NC_010473.1 3670839 3671432 D YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); putative dITP- and XTP- hydrolase 3670839..3671432 Escherichia coli str. K-12 substr. DH10B 6060337 YP_001732270.1 CDS gntU NC_010473.1 3671489 3672829 R low affinity gluconate transporter complement(3671489..3672829) Escherichia coli str. K-12 substr. DH10B 6060691 YP_001732271.1 CDS gntK NC_010473.1 3672833 3673360 R thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase complement(3672833..3673360) Escherichia coli str. K-12 substr. DH10B 6060707 YP_001732272.1 CDS gntR NC_010473.1 3673499 3674494 R DNA-binding transcriptional repressor complement(3673499..3674494) Escherichia coli str. K-12 substr. DH10B 6060554 YP_001732273.1 CDS yhhW NC_010473.1 3674718 3675413 R hypothetical protein complement(3674718..3675413) Escherichia coli str. K-12 substr. DH10B 6060269 YP_001732274.1 CDS yhhX NC_010473.1 3675536 3676573 R putative dehydrogenase complement(3675536..3676573) Escherichia coli str. K-12 substr. DH10B 6062169 YP_001732275.1 CDS yhhY NC_010473.1 3676906 3677394 D YhhY; regulated by the fur regulator; unknown function; putative acetyltransferase YhhY 3676906..3677394 Escherichia coli str. K-12 substr. DH10B 6058979 YP_001732276.1 CDS yhhZ NC_010473.1 3677631 3678809 D hypothetical protein 3677631..3678809 Escherichia coli str. K-12 substr. DH10B 6060660 YP_001732277.1 CDS yrhA NC_010473.1 3678809 3679222 D hypothetical protein 3678809..3679222 Escherichia coli str. K-12 substr. DH10B 6062093 YP_001732278.1 CDS insA-6 NC_010473.1 3679251 3679526 D IS1 repressor protein InsA 3679251..3679526 Escherichia coli str. K-12 substr. DH10B 6061072 YP_001732279.1 CDS insB-6 NC_010473.1 3679445 3679948 D IS1 transposase InsAB' 3679445..3679948 Escherichia coli str. K-12 substr. DH10B 6061027 YP_001732280.1 CDS yrhB NC_010473.1 3680527 3680811 D hypothetical protein 3680527..3680811 Escherichia coli str. K-12 substr. DH10B 6062067 YP_001732281.1 CDS ggt NC_010473.1 3680849 3682591 R periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase complement(3680849..3682591) Escherichia coli str. K-12 substr. DH10B 6061045 YP_001732282.1 CDS yhhA NC_010473.1 3682711 3683151 D hypothetical protein 3682711..3683151 Escherichia coli str. K-12 substr. DH10B 6062017 YP_001732283.1 CDS ugpQ NC_010473.1 3683138 3683881 R hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; glycerophosphodiester phosphodiesterase complement(3683138..3683881) Escherichia coli str. K-12 substr. DH10B 6062029 YP_001732284.1 CDS ugpC NC_010473.1 3683878 3684948 R part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit complement(3683878..3684948) Escherichia coli str. K-12 substr. DH10B 6061968 YP_001732285.1 CDS ugpE NC_010473.1 3684950 3685795 R with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein complement(3684950..3685795) Escherichia coli str. K-12 substr. DH10B 6061017 YP_001732286.1 CDS ugpA NC_010473.1 3685792 3686679 R with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease complement(3685792..3686679) Escherichia coli str. K-12 substr. DH10B 6061006 YP_001732287.1 CDS ugpB NC_010473.1 3686777 3688093 R with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein complement(3686777..3688093) Escherichia coli str. K-12 substr. DH10B 6060999 YP_001732288.1 CDS livF NC_010473.1 3688492 3689205 R with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(3688492..3689205) Escherichia coli str. K-12 substr. DH10B 6061919 YP_001732289.1 CDS livG NC_010473.1 3689207 3689974 R Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(3689207..3689974) Escherichia coli str. K-12 substr. DH10B 6061984 YP_001732290.1 CDS livM NC_010473.1 3689971 3691248 R Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit complement(3689971..3691248) Escherichia coli str. K-12 substr. DH10B 6060932 YP_001732291.1 CDS livH NC_010473.1 3691245 3692171 R LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH complement(3691245..3692171) Escherichia coli str. K-12 substr. DH10B 6060794 YP_001732292.1 CDS livK NC_010473.1 3692219 3693328 R leucine ABC transporter periplasmic-binding component complement(3692219..3693328) Escherichia coli str. K-12 substr. DH10B 6061623 YP_001732293.1 CDS yhhK NC_010473.1 3693752 3694135 D hypothetical protein 3693752..3694135 Escherichia coli str. K-12 substr. DH10B 6061630 YP_001732294.1 CDS livJ NC_010473.1 3694323 3695426 R leucine/isoleucine/valine ABC transporter periplasmic-binding component complement(3694323..3695426) Escherichia coli str. K-12 substr. DH10B 6061574 YP_001732295.1 CDS rpoH NC_010473.1 3695697 3696551 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(3695697..3696551) Escherichia coli str. K-12 substr. DH10B 6061532 YP_001732296.1 CDS ftsX NC_010473.1 3696796 3697854 R putative ABC transporter, membrane protein; cell division protein FtsX complement(3696796..3697854) Escherichia coli str. K-12 substr. DH10B 6060758 YP_001732297.1 CDS ftsE NC_010473.1 3697847 3698515 R putative ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE complement(3697847..3698515) Escherichia coli str. K-12 substr. DH10B 6060772 YP_001732298.1 CDS ftsY NC_010473.1 3698518 3700011 R signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY complement(3698518..3700011) Escherichia coli str. K-12 substr. DH10B 6061689 YP_001732299.1 CDS rsmD NC_010473.1 3700161 3700757 D catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 3700161..3700757 Escherichia coli str. K-12 substr. DH10B 6061676 YP_001732300.1 CDS yhhL NC_010473.1 3700747 3701016 D hypothetical protein 3700747..3701016 Escherichia coli str. K-12 substr. DH10B 6061651 YP_001732301.1 CDS yhhM NC_010473.1 3701019 3701378 R hypothetical protein complement(3701019..3701378) Escherichia coli str. K-12 substr. DH10B 6061737 YP_001732302.1 CDS yhhN NC_010473.1 3701519 3702145 D inner membrane protein 3701519..3702145 Escherichia coli str. K-12 substr. DH10B 6060862 YP_001732303.1 CDS zntA NC_010473.1 3702219 3704417 D P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 3702219..3704417 Escherichia coli str. K-12 substr. DH10B 6060788 YP_001732304.1 CDS sirA NC_010473.1 3704519 3704764 R TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA complement(3704519..3704764) Escherichia coli str. K-12 substr. DH10B 6061870 YP_001732305.1 CDS yhhQ NC_010473.1 3704985 3705650 D hypothetical protein 3704985..3705650 Escherichia coli str. K-12 substr. DH10B 6060880 YP_001732306.1 CDS dcrB NC_010473.1 3705723 3706280 D hypothetical protein 3705723..3706280 Escherichia coli str. K-12 substr. DH10B 6060782 YP_001732307.1 CDS yhhS NC_010473.1 3706284 3707501 R major facilitator superfamily transporter complement(3706284..3707501) Escherichia coli str. K-12 substr. DH10B 6060565 YP_001732308.1 CDS yhhT NC_010473.1 3707633 3708682 D inner membrane protein 3707633..3708682 Escherichia coli str. K-12 substr. DH10B 6061502 YP_001732309.1 CDS acpT NC_010473.1 3708737 3709324 D holo-(acyl carrier protein) synthase 2 3708737..3709324 Escherichia coli str. K-12 substr. DH10B 6061501 YP_001732310.1 CDS nikA NC_010473.1 3709435 3711009 D nickel ABC transporter periplasmic substrate-binding proteinsuperfamily 3709435..3711009 Escherichia coli str. K-12 substr. DH10B 6061813 YP_001732311.1 CDS nikB NC_010473.1 3711009 3711953 D with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 3711009..3711953 Escherichia coli str. K-12 substr. DH10B 6060831 YP_001732312.1 CDS nikC NC_010473.1 3711950 3712783 D with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 3711950..3712783 Escherichia coli str. K-12 substr. DH10B 6060878 YP_001732313.1 CDS nikD NC_010473.1 3712783 3713547 D with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 3712783..3713547 Escherichia coli str. K-12 substr. DH10B 6061915 YP_001732314.1 CDS nikE NC_010473.1 3713544 3714350 D with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 3713544..3714350 Escherichia coli str. K-12 substr. DH10B 6060953 YP_001732315.1 CDS nikR NC_010473.1 3714356 3714757 D Inhibits transcription at high concentrations of nickel; nickel responsive regulator 3714356..3714757 Escherichia coli str. K-12 substr. DH10B 6061845 YP_001732316.1 CDS rhsB NC_010473.1 3714960 3719195 D rhsB element core protein RshB 3714960..3719195 Escherichia coli str. K-12 substr. DH10B 6059476 YP_001732317.1 CDS yhhH NC_010473.1 3719167 3719550 D hypothetical protein 3719167..3719550 Escherichia coli str. K-12 substr. DH10B 6059504 YP_001732318.1 CDS yhhI NC_010473.1 3720146 3721282 D transposase 3720146..3721282 Escherichia coli str. K-12 substr. DH10B 6059516 YP_001732319.1 CDS yhhJ NC_010473.1 3721447 3722571 R ABC transporter membrane protein complement(3721447..3722571) Escherichia coli str. K-12 substr. DH10B 6059342 YP_001732320.1 CDS rbbA NC_010473.1 3722571 3725306 R fused ribosome-associated ATPase: ATP-binding protein; ATP-binding protein; membrane protein complement(3722571..3725306) Escherichia coli str. K-12 substr. DH10B 6059322 YP_001732321.1 CDS yhiJ NC_010473.1 3726736 3728358 R hypothetical protein complement(3726736..3728358) Escherichia coli str. K-12 substr. DH10B 6059319 YP_001732322.1 CDS yhiM NC_010473.1 3730609 3731661 D inner membrane protein 3730609..3731661 Escherichia coli str. K-12 substr. DH10B 6060646 YP_001732323.1 CDS yhiN NC_010473.1 3731976 3733178 R oxidoreductase complement(3731976..3733178) Escherichia coli str. K-12 substr. DH10B 6059275 YP_001732324.1 CDS pitA NC_010473.1 3733410 3734909 D phosphate transporter, low-affinity 3733410..3734909 Escherichia coli str. K-12 substr. DH10B 6059276 YP_001732325.1 CDS uspB NC_010473.1 3735153 3735488 R ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB complement(3735153..3735488) Escherichia coli str. K-12 substr. DH10B 6059291 YP_001732326.1 CDS uspA NC_010473.1 3735879 3736313 D universal stress global response regulator 3735879..3736313 Escherichia coli str. K-12 substr. DH10B 6059258 YP_001732327.1 CDS yhiP NC_010473.1 3736630 3738099 D member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 3736630..3738099 Escherichia coli str. K-12 substr. DH10B 6059253 YP_001732328.1 CDS yhiQ NC_010473.1 3738148 3738900 R predicted SAM-dependent methyltransferase; putative methyltransferase complement(3738148..3738900) Escherichia coli str. K-12 substr. DH10B 6059194 YP_001732329.1 CDS prlC NC_010473.1 3738908 3740950 R oligopeptidase A complement(3738908..3740950) Escherichia coli str. K-12 substr. DH10B 6061226 YP_001732330.1 CDS yhiR NC_010473.1 3741153 3741995 D DNA (exogenous) processing protein 3741153..3741995 Escherichia coli str. K-12 substr. DH10B 6058314 YP_001732331.1 CDS gor NC_010473.1 3742067 3743419 D catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 3742067..3743419 Escherichia coli str. K-12 substr. DH10B 6058494 YP_001732332.1 CDS arsR NC_010473.1 3744296 3744649 D regulates the expression of of the arsRBC involved in resistance to arsenic; DNA-binding transcriptional repressor ArsR 3744296..3744649 Escherichia coli str. K-12 substr. DH10B 6058423 YP_001732333.1 CDS arsB NC_010473.1 3744703 3745992 D arsenite/antimonite transporter 3744703..3745992 Escherichia coli str. K-12 substr. DH10B 6062297 YP_001732334.1 CDS arsC NC_010473.1 3746005 3746430 D arsenate reductase 3746005..3746430 Escherichia coli str. K-12 substr. DH10B 6058451 YP_001732335.1 CDS yhiS NC_010473.1 3747059 3747841 D hypothetical protein 3747059..3747841 Escherichia coli str. K-12 substr. DH10B 6058123 YP_001732336.1 CDS insH-11 NC_010473.1 3747950 3748966 R IS5 transposase and trans-activator complement(3747950..3748966) Escherichia coli str. K-12 substr. DH10B 6058356 YP_001732337.1 CDS slp NC_010473.1 3749729 3750295 D outer membrane lipoprotein 3749729..3750295 Escherichia coli str. K-12 substr. DH10B 6062268 YP_001732338.1 CDS yhiF NC_010473.1 3750451 3750981 D DNA-binding ranscriptional regulator 3750451..3750981 Escherichia coli str. K-12 substr. DH10B 6059229 YP_001732339.1 CDS yhiD NC_010473.1 3751023 3751670 R inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; putative Mg(2+) transport ATPase complement(3751023..3751670) Escherichia coli str. K-12 substr. DH10B 6059140 YP_001732340.1 CDS hdeB NC_010473.1 3751734 3752060 R acid-resistance protein complement(3751734..3752060) Escherichia coli str. K-12 substr. DH10B 6059135 YP_001732341.1 CDS hdeA NC_010473.1 3752176 3752508 R inactive form; acid-resistance protein complement(3752176..3752508) Escherichia coli str. K-12 substr. DH10B 6059193 YP_001732342.1 CDS hdeD NC_010473.1 3752763 3753335 D acid-resistance membrane protein 3752763..3753335 Escherichia coli str. K-12 substr. DH10B 6059201 YP_001732343.1 CDS gadE NC_010473.1 3754134 3754661 D acid-induced positive regulator of glutamate-dependent acid resistance 3754134..3754661 Escherichia coli str. K-12 substr. DH10B 6059166 YP_001732344.1 CDS mdtE NC_010473.1 3755000 3756157 D with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 3755000..3756157 Escherichia coli str. K-12 substr. DH10B 6059151 YP_001732345.1 CDS mdtF NC_010473.1 3756182 3759295 D multidrug transporter, RpoS-dependent 3756182..3759295 Escherichia coli str. K-12 substr. DH10B 6059132 YP_001732346.1 CDS gadW NC_010473.1 3759658 3760386 R DNA-binding transcriptional activator complement(3759658..3760386) Escherichia coli str. K-12 substr. DH10B 6059159 YP_001732347.1 CDS gadX NC_010473.1 3760754 3761578 R regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX complement(3760754..3761578) Escherichia coli str. K-12 substr. DH10B 6058913 YP_001732348.1 CDS gadA NC_010473.1 3761948 3763348 R glutamate decarboxylase complement(3761948..3763348) Escherichia coli str. K-12 substr. DH10B 6059024 YP_001732349.1 CDS yhjA NC_010473.1 3763559 3764956 R cytochrome C peroxidase complement(3763559..3764956) Escherichia coli str. K-12 substr. DH10B 6059089 YP_001732350.1 CDS treF NC_010473.1 3765360 3767009 D cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 3765360..3767009 Escherichia coli str. K-12 substr. DH10B 6059091 YP_001732351.1 CDS yhjB NC_010473.1 3767060 3767662 R DNA-binding response regulator in two-component regulatory system complement(3767060..3767662) Escherichia coli str. K-12 substr. DH10B 6058970 YP_001732352.1 CDS yhjC NC_010473.1 3768110 3769081 D DNA-binding transcriptional regulator 3768110..3769081 Escherichia coli str. K-12 substr. DH10B 6059028 YP_001732353.1 CDS yhjD NC_010473.1 3769130 3770143 D inner membrane protein 3769130..3770143 Escherichia coli str. K-12 substr. DH10B 6059013 YP_001732354.1 CDS yhjE NC_010473.1 3770554 3771876 D transporter 3770554..3771876 Escherichia coli str. K-12 substr. DH10B 6059002 YP_001732355.1 CDS yhjG NC_010473.1 3772058 3774133 R outer membrane biogenesis protein complement(3772058..3774133) Escherichia coli str. K-12 substr. DH10B 6058924 YP_001732356.1 CDS yhjH NC_010473.1 3774188 3774955 R in Escherichia coli this protein is involved in flagellar function; EAL domain-containing protein complement(3774188..3774955) Escherichia coli str. K-12 substr. DH10B 6061340 YP_001732357.1 CDS kdgK NC_010473.1 3775187 3776116 D ketodeoxygluconokinase 3775187..3776116 Escherichia coli str. K-12 substr. DH10B 6058947 YP_001732358.1 CDS yhjJ NC_010473.1 3776212 3777708 R zinc-dependent peptidase complement(3776212..3777708) Escherichia coli str. K-12 substr. DH10B 6058940 YP_001732359.1 CDS yhjK NC_010473.1 3779398 3781347 R HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a putative phosphodiesterase protein from E. coli; putative phosphodiesterase complement(3779398..3781347) Escherichia coli str. K-12 substr. DH10B 6058876 YP_001732360.1 CDS bcsC NC_010473.1 3781468 3784941 R cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC complement(3781468..3784941) Escherichia coli str. K-12 substr. DH10B 6058880 YP_001732361.1 CDS bcsZ NC_010473.1 3784923 3786029 R catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase complement(3784923..3786029) Escherichia coli str. K-12 substr. DH10B 6058894 YP_001732362.1 CDS bcsB NC_010473.1 3786036 3788375 R binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein complement(3786036..3788375) Escherichia coli str. K-12 substr. DH10B 6058936 YP_001732363.1 CDS bcsA NC_010473.1 3788386 3791004 R polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit complement(3788386..3791004) Escherichia coli str. K-12 substr. DH10B 6058813 YP_001732364.1 CDS yhjR NC_010473.1 3791765 3791953 R hypothetical protein complement(3791765..3791953) Escherichia coli str. K-12 substr. DH10B 6059447 YP_001732365.1 CDS bcsF NC_010473.1 3793794 3793985 D hypothetical protein 3793794..3793985 Escherichia coli str. K-12 substr. DH10B 6058838 YP_001732366.1 CDS bcsG NC_010473.1 3793982 3795661 D inner membrane protein 3793982..3795661 Escherichia coli str. K-12 substr. DH10B 6058866 YP_001732367.1 CDS ldrD NC_010473.1 3795748 3795855 R toxic polypeptide, small complement(3795748..3795855) Escherichia coli str. K-12 substr. DH10B 6058730 YP_001732368.1 CDS yhjV NC_010473.1 3796331 3797602 D transporter 3796331..3797602 Escherichia coli str. K-12 substr. DH10B 6058867 YP_001732369.1 CDS dppF NC_010473.1 3797632 3798636 R Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit complement(3797632..3798636) Escherichia coli str. K-12 substr. DH10B 6058713 YP_001732370.1 CDS dppD NC_010473.1 3798633 3799616 R DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit complement(3798633..3799616) Escherichia coli str. K-12 substr. DH10B 6058811 YP_001732371.1 CDS dppC NC_010473.1 3799627 3800529 R dipeptide transporter complement(3799627..3800529) Escherichia coli str. K-12 substr. DH10B 6058635 YP_001732372.1 CDS dppB NC_010473.1 3800539 3801558 R transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB complement(3800539..3801558) Escherichia coli str. K-12 substr. DH10B 6060743 YP_001732373.1 CDS dppA NC_010473.1 3801866 3803473 R peptide ABC transporter periplasmic substrate-binding protein complement(3801866..3803473) Escherichia coli str. K-12 substr. DH10B 6058698 YP_001732374.1 CDS eptB NC_010473.1 3804384 3806075 R catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase complement(3804384..3806075) Escherichia coli str. K-12 substr. DH10B 6058810 YP_001732375.1 CDS yhjX NC_010473.1 3806399 3807607 R transporter complement(3806399..3807607) Escherichia coli str. K-12 substr. DH10B 6058565 YP_001732376.1 CDS yhjY NC_010473.1 3807836 3808534 R hypothetical protein complement(3807836..3808534) Escherichia coli str. K-12 substr. DH10B 6058487 YP_001732377.1 CDS tag NC_010473.1 3808692 3809255 D constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyladenine DNA glycosylase 3808692..3809255 Escherichia coli str. K-12 substr. DH10B 6058528 YP_001732378.1 CDS yiaC NC_010473.1 3809252 3809692 D hypothetical protein 3809252..3809692 Escherichia coli str. K-12 substr. DH10B 6060166 YP_001732379.1 CDS bisC NC_010473.1 3809661 3811940 R biotin sulfoxide reductase complement(3809661..3811940) Escherichia coli str. K-12 substr. DH10B 6058125 YP_001732380.1 CDS yiaD NC_010473.1 3812147 3812806 D putative outer membrane lipoprotein 3812147..3812806 Escherichia coli str. K-12 substr. DH10B 6058362 YP_001732381.1 CDS tiaE NC_010473.1 3812910 3813884 D 2-keto-D-gluconate reductase (glyoxalate reductase) (2-ketoaldonate reductase) 3812910..3813884 Escherichia coli str. K-12 substr. DH10B 6058427 YP_001732382.1 CDS yiaF NC_010473.1 3813934 3814644 R hypothetical protein complement(3813934..3814644) Escherichia coli str. K-12 substr. DH10B 6058102 YP_001732383.1 CDS yiaG NC_010473.1 3815078 3815368 D putative transcriptional regulator 3815078..3815368 Escherichia coli str. K-12 substr. DH10B 6058377 YP_001732384.1 CDS cspA NC_010473.1 3815649 3815861 D major cold shock protein 3815649..3815861 Escherichia coli str. K-12 substr. DH10B 6058592 YP_001732385.1 CDS hokA NC_010473.1 3816048 3816200 R small toxic polypeptide complement(3816048..3816200) Escherichia coli str. K-12 substr. DH10B 6058336 YP_001732386.1 CDS insJ NC_010473.1 3816280 3816801 D IS150 protein InsA 3816280..3816801 Escherichia coli str. K-12 substr. DH10B 6058292 YP_001732387.1 CDS insK NC_010473.1 3816798 3817649 D IS150 protein InsB 3816798..3817649 Escherichia coli str. K-12 substr. DH10B 6058414 YP_001732388.1 CDS glyS NC_010473.1 3817928 3819997 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(3817928..3819997) Escherichia coli str. K-12 substr. DH10B 6058311 YP_001732389.1 CDS ysaB NC_010473.1 3821013 3821312 R hypothetical protein complement(3821013..3821312) Escherichia coli str. K-12 substr. DH10B 6058569 YP_001732390.1 CDS yiaH NC_010473.1 3821487 3822482 D inner membrane protein 3821487..3822482 Escherichia coli str. K-12 substr. DH10B 6058351 YP_001732391.1 CDS yiaA NC_010473.1 3822524 3822961 R hypothetical protein complement(3822524..3822961) Escherichia coli str. K-12 substr. DH10B 6058261 YP_001732392.1 CDS yiaB NC_010473.1 3823007 3823348 R hypothetical protein complement(3823007..3823348) Escherichia coli str. K-12 substr. DH10B 6058535 YP_001732393.1 CDS xylB NC_010473.1 3823517 3824971 R xylulokinase complement(3823517..3824971) Escherichia coli str. K-12 substr. DH10B 6058551 YP_001732394.1 CDS xylA NC_010473.1 3825043 3826365 R catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase complement(3825043..3826365) Escherichia coli str. K-12 substr. DH10B 6062400 YP_001732395.1 CDS xylF NC_010473.1 3826731 3827723 D periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 3826731..3827723 Escherichia coli str. K-12 substr. DH10B 6059130 YP_001732396.1 CDS xylG NC_010473.1 3827801 3829342 D with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 3827801..3829342 Escherichia coli str. K-12 substr. DH10B 6059469 YP_001732397.1 CDS xylH NC_010473.1 3829320 3830501 D D-xylose ABC transporter membrane protein 3829320..3830501 Escherichia coli str. K-12 substr. DH10B 6058185 YP_001732398.1 CDS xylR NC_010473.1 3830579 3831757 D DNA-binding transcriptional activator, xylose-binding 3830579..3831757 Escherichia coli str. K-12 substr. DH10B 6059460 YP_001732399.1 CDS bax NC_010473.1 3831953 3832777 R hypothetical protein complement(3831953..3832777) Escherichia coli str. K-12 substr. DH10B 6059451 YP_001732400.1 CDS malS NC_010473.1 3833097 3835127 D periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 3833097..3835127 Escherichia coli str. K-12 substr. DH10B 6059446 YP_001732401.1 CDS avtA NC_010473.1 3835305 3836558 D transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 3835305..3836558 Escherichia coli str. K-12 substr. DH10B 6058540 YP_001732402.1 CDS ysaA NC_010473.1 3836709 3837182 R hydrogenase, 4Fe-4S ferredoxin-type component complement(3836709..3837182) Escherichia coli str. K-12 substr. DH10B 6059441 YP_001732403.1 CDS yiaJ NC_010473.1 3837284 3838132 R DNA-binding transcriptional repressor complement(3837284..3838132) Escherichia coli str. K-12 substr. DH10B 6059430 YP_001732404.1 CDS yiaK NC_010473.1 3838333 3839331 D NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 3838333..3839331 Escherichia coli str. K-12 substr. DH10B 6058124 YP_001732405.1 CDS yiaL NC_010473.1 3839343 3839810 D hypothetical protein 3839343..3839810 Escherichia coli str. K-12 substr. DH10B 6059420 YP_001732406.1 CDS yiaM NC_010473.1 3839928 3840401 D membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO; 2,3-diketo-L-gulonate TRAP transporter small permease 3839928..3840401 Escherichia coli str. K-12 substr. DH10B 6059411 YP_001732407.1 CDS yiaN NC_010473.1 3840404 3841681 D transporter 3840404..3841681 Escherichia coli str. K-12 substr. DH10B 6059492 YP_001732408.1 CDS yiaO NC_010473.1 3841694 3842680 D transporter 3841694..3842680 Escherichia coli str. K-12 substr. DH10B 6059417 YP_001732409.1 CDS lyxK NC_010473.1 3842684 3844180 D L-xylulose kinase 3842684..3844180 Escherichia coli str. K-12 substr. DH10B 6059390 YP_001732410.1 CDS sgbH NC_010473.1 3844177 3844839 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate; 3-keto-L-gulonate-6-phosphate decarboxylase 3844177..3844839 Escherichia coli str. K-12 substr. DH10B 6058426 YP_001732411.1 CDS sgbU NC_010473.1 3844832 3845692 D L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; putative L-xylulose 5-phosphate 3-epimerase 3844832..3845692 Escherichia coli str. K-12 substr. DH10B 6058239 YP_001732412.1 CDS sgbE NC_010473.1 3845686 3846381 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 3845686..3846381 Escherichia coli str. K-12 substr. DH10B 6062156 YP_001732413.1 CDS yiaT NC_010473.1 3846728 3847468 R hypothetical protein complement(3846728..3847468) Escherichia coli str. K-12 substr. DH10B 6059588 YP_001732414.1 CDS yiaU NC_010473.1 3847592 3848566 D DNA-binding transcriptional regulator 3847592..3848566 Escherichia coli str. K-12 substr. DH10B 6059616 YP_001732415.1 CDS yiaV NC_010473.1 3848563 3849699 R membrane fusion protein (MFP) component of efflux pump, signal anchor complement(3848563..3849699) Escherichia coli str. K-12 substr. DH10B 6059641 YP_001732416.1 CDS yiaW NC_010473.1 3849705 3850028 R inner membrane protein complement(3849705..3850028) Escherichia coli str. K-12 substr. DH10B 6059610 YP_001732417.1 CDS aldB NC_010473.1 3850573 3852111 R aldehyde dehydrogenase B complement(3850573..3852111) Escherichia coli str. K-12 substr. DH10B 6059637 YP_001732418.1 CDS yiaY NC_010473.1 3852276 3853427 R putative alcohol dehydrogenase complement(3852276..3853427) Escherichia coli str. K-12 substr. DH10B 6059705 YP_001732419.1 CDS selB NC_010473.1 3853617 3855461 R selenocysteinyl-tRNA-specific translation factor complement(3853617..3855461) Escherichia coli str. K-12 substr. DH10B 6058483 YP_001732420.1 CDS yibF NC_010473.1 3856947 3857555 R putative glutathione S-transferase complement(3856947..3857555) Escherichia coli str. K-12 substr. DH10B 6058408 YP_001732421.1 CDS yibA NC_010473.1 3861937 3862779 D hypothetical protein 3861937..3862779 Escherichia coli str. K-12 substr. DH10B 6058412 YP_001732422.1 CDS yibJ NC_010473.1 3862821 3863522 D Rhs-family protein 3862821..3863522 Escherichia coli str. K-12 substr. DH10B 6058264 YP_001732423.1 CDS yibG NC_010473.1 3863777 3864238 D hypothetical protein 3863777..3864238 Escherichia coli str. K-12 substr. DH10B 6059740 YP_001732424.1 CDS yibH NC_010473.1 3865843 3866979 R hypothetical protein complement(3865843..3866979) Escherichia coli str. K-12 substr. DH10B 6058110 YP_001732425.1 CDS yibI NC_010473.1 3866982 3867344 R inner membrane protein complement(3866982..3867344) Escherichia coli str. K-12 substr. DH10B 6058318 YP_001732426.1 CDS mtlA NC_010473.1 3867881 3869794 D fused mannitol-specific PTS enzymes: IIA components; IIB components; IIC components 3867881..3869794 Escherichia coli str. K-12 substr. DH10B 6058279 YP_001732427.1 CDS mtlD NC_010473.1 3870024 3871172 D mannitol-1-phosphate 5-dehydrogenase 3870024..3871172 Escherichia coli str. K-12 substr. DH10B 6058514 YP_001732428.1 CDS mtlR NC_010473.1 3871172 3871759 D Acts as a repressor of the mtlAD operon; mannitol repressor protein 3871172..3871759 Escherichia coli str. K-12 substr. DH10B 6058193 YP_001732429.1 CDS yibT NC_010473.1 3871771 3871980 R hypothetical protein complement(3871771..3871980) Escherichia coli str. K-12 substr. DH10B 6058135 YP_001732430.1 CDS yibL NC_010473.1 3872265 3872627 D hypothetical protein 3872265..3872627 Escherichia coli str. K-12 substr. DH10B 6058211 YP_001732431.1 CDS lldP NC_010473.1 3872999 3874654 D L-lactate permease 3872999..3874654 Escherichia coli str. K-12 substr. DH10B 6058223 YP_001732432.1 CDS lldR NC_010473.1 3874654 3875430 D represses the lctPRD operon; DNA-binding transcriptional repressor LldR 3874654..3875430 Escherichia coli str. K-12 substr. DH10B 6058131 YP_001732433.1 CDS lldD NC_010473.1 3875427 3876617 D flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 3875427..3876617 Escherichia coli str. K-12 substr. DH10B 6058555 YP_001732434.1 CDS yibK NC_010473.1 3876815 3877288 D member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; putative tRNA/rRNA methyltransferase YibK 3876815..3877288 Escherichia coli str. K-12 substr. DH10B 6058477 YP_001732435.1 CDS cysE NC_010473.1 3877341 3878162 R catalyzes the O-acetylation of serine; serine acetyltransferase complement(3877341..3878162) Escherichia coli str. K-12 substr. DH10B 6058545 YP_001732436.1 CDS gpsA NC_010473.1 3878242 3879261 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(3878242..3879261) Escherichia coli str. K-12 substr. DH10B 6058267 YP_001732437.1 CDS secB NC_010473.1 3879261 3879728 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB complement(3879261..3879728) Escherichia coli str. K-12 substr. DH10B 6058410 YP_001732438.1 CDS grxC NC_010473.1 3879791 3880042 R glutaredoxin 3 complement(3879791..3880042) Escherichia coli str. K-12 substr. DH10B 6058583 YP_001732439.1 CDS yibN NC_010473.1 3880184 3880615 R rhodanese-related sulfurtransferase complement(3880184..3880615) Escherichia coli str. K-12 substr. DH10B 6059817 YP_001732440.1 CDS gpmI NC_010473.1 3880860 3882404 D catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 3880860..3882404 Escherichia coli str. K-12 substr. DH10B 6059831 YP_001732441.2 CDS envC NC_010473.1 3882414 3883697 D hypothetical protein 3882414..3883697 Escherichia coli str. K-12 substr. DH10B 6058310 YP_001732442.1 CDS yibQ NC_010473.1 3883701 3884660 D polysaccharide deacetylase 3883701..3884660 Escherichia coli str. K-12 substr. DH10B 6059874 YP_001732443.1 CDS yibD NC_010473.1 3884647 3885681 R putative glycosyl transferase complement(3884647..3885681) Escherichia coli str. K-12 substr. DH10B 6059882 YP_001732444.1 CDS tdh NC_010473.1 3885920 3886945 R converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase complement(3885920..3886945) Escherichia coli str. K-12 substr. DH10B 6059902 YP_001732445.1 CDS kbl NC_010473.1 3886955 3888151 R catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase complement(3886955..3888151) Escherichia coli str. K-12 substr. DH10B 6059968 YP_001732446.1 CDS htrL NC_010473.1 3888426 3889283 R hypothetical protein complement(3888426..3889283) Escherichia coli str. K-12 substr. DH10B 6058444 YP_001732447.1 CDS rfaD NC_010473.1 3889587 3890519 D catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 3889587..3890519 Escherichia coli str. K-12 substr. DH10B 6058213 YP_001732448.1 CDS rfaF NC_010473.1 3890529 3891575 D catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose--LPS heptosyltransferase 3890529..3891575 Escherichia coli str. K-12 substr. DH10B 6058611 YP_001732449.1 CDS rfaC NC_010473.1 3891579 3892538 D ADP-heptose--LPS heptosyltransferase 3891579..3892538 Escherichia coli str. K-12 substr. DH10B 6058194 YP_001732450.1 CDS rfaL NC_010473.1 3892548 3893807 D O-antigen ligase 3892548..3893807 Escherichia coli str. K-12 substr. DH10B 6058443 YP_001732451.1 CDS rfaK NC_010473.1 3893839 3894912 R lipopolysaccharide core biosynthesis protein complement(3893839..3894912) Escherichia coli str. K-12 substr. DH10B 6058515 YP_001732452.1 CDS rfaZ NC_010473.1 3894945 3895796 R lipopolysaccharide core biosynthesis protein complement(3894945..3895796) Escherichia coli str. K-12 substr. DH10B 6058395 YP_001732453.1 CDS rfaY NC_010473.1 3895867 3896565 R lipopolysaccharide core biosynthesis protein complement(3895867..3896565) Escherichia coli str. K-12 substr. DH10B 6058413 YP_001732454.1 CDS rfaJ NC_010473.1 3896583 3897599 R UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase complement(3896583..3897599) Escherichia coli str. K-12 substr. DH10B 6058482 YP_001732455.1 CDS rfaI NC_010473.1 3897639 3898658 R UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase complement(3897639..3898658) Escherichia coli str. K-12 substr. DH10B 6058501 YP_001732456.1 CDS rfaB NC_010473.1 3898658 3899767 R UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase complement(3898658..3899767) Escherichia coli str. K-12 substr. DH10B 6060068 YP_001732457.1 CDS rfaS NC_010473.1 3899781 3900716 R lipopolysaccharide core biosynthesis protein complement(3899781..3900716) Escherichia coli str. K-12 substr. DH10B 6058112 YP_001732458.1 CDS rfaP NC_010473.1 3900753 3901550 R kinase that phosphorylates core heptose of lipopolysaccharide complement(3900753..3901550) Escherichia coli str. K-12 substr. DH10B 6058388 YP_001732459.1 CDS rfaG NC_010473.1 3901543 3902667 R glucosyltransferase I complement(3901543..3902667) Escherichia coli str. K-12 substr. DH10B 6058520 YP_001732460.1 CDS rfaQ NC_010473.1 3902664 3903698 R lipopolysaccharide core biosynthesis protein complement(3902664..3903698) Escherichia coli str. K-12 substr. DH10B 6060080 YP_001732461.1 CDS kdtA NC_010473.1 3904140 3905417 D catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 3904140..3905417 Escherichia coli str. K-12 substr. DH10B 6060097 YP_001732462.1 CDS coaD NC_010473.1 3905425 3905904 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 3905425..3905904 Escherichia coli str. K-12 substr. DH10B 6058401 YP_001732463.1 CDS mutM NC_010473.1 3905943 3906752 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(3905943..3906752) Escherichia coli str. K-12 substr. DH10B 6058465 YP_001732464.1 CDS rpmG NC_010473.1 3906850 3907017 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(3906850..3907017) Escherichia coli str. K-12 substr. DH10B 6058499 YP_001732465.1 CDS rpmB NC_010473.1 3907038 3907274 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(3907038..3907274) Escherichia coli str. K-12 substr. DH10B 6058417 YP_001732466.1 CDS radC NC_010473.1 3907491 3908159 R Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC complement(3907491..3908159) Escherichia coli str. K-12 substr. DH10B 6058532 YP_001732467.1 CDS dfp NC_010473.1 3908331 3909551 D catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 3908331..3909551 Escherichia coli str. K-12 substr. DH10B 6058288 YP_001732468.1 CDS dut NC_010473.1 3909532 3909987 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 3909532..3909987 Escherichia coli str. K-12 substr. DH10B 6058409 YP_001732469.1 CDS slmA NC_010473.1 3910094 3910690 D FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 3910094..3910690 Escherichia coli str. K-12 substr. DH10B 6058287 YP_001732470.1 CDS pyrE NC_010473.1 3910727 3911368 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(3910727..3911368) Escherichia coli str. K-12 substr. DH10B 6060170 YP_001732471.1 CDS yicC NC_010473.1 3912277 3913140 D hypothetical protein 3912277..3913140 Escherichia coli str. K-12 substr. DH10B 6060181 YP_001732472.1 CDS dinD NC_010473.1 3913361 3914185 D DNA-damage-inducible protein D 3913361..3914185 Escherichia coli str. K-12 substr. DH10B 6058126 YP_001732473.1 CDS yicG NC_010473.1 3914475 3915092 D inner membrane protein 3914475..3915092 Escherichia coli str. K-12 substr. DH10B 6058425 YP_001732474.1 CDS ligB NC_010473.1 3915089 3916771 R this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB complement(3915089..3916771) Escherichia coli str. K-12 substr. DH10B 6058350 YP_001732475.1 CDS gmk NC_010473.1 3917029 3917652 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 3917029..3917652 Escherichia coli str. K-12 substr. DH10B 6058263 YP_001732476.1 CDS rpoZ NC_010473.1 3917707 3917982 D promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 3917707..3917982 Escherichia coli str. K-12 substr. DH10B 6058385 YP_001732477.1 CDS spoT NC_010473.1 3918001 3920115 D contains a six base pair insertion resulting in addition of Gln-Asp after amino acid 84, within the overlapping hydrolase and synthetase domains, as well as a SNP causing the H257Y substitution in the regulatory domain; bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 3918001..3920115 Escherichia coli str. K-12 substr. DH10B 6058154 YP_001732478.1 CDS spoU NC_010473.1 3920122 3920811 D specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 3920122..3920811 Escherichia coli str. K-12 substr. DH10B 6058601 YP_001732479.1 CDS recG NC_010473.1 3920817 3922898 D catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 3920817..3922898 Escherichia coli str. K-12 substr. DH10B 6060245 YP_001732480.1 CDS gltS NC_010473.1 3923067 3924272 R glutamate transporter complement(3923067..3924272) Escherichia coli str. K-12 substr. DH10B 6060247 YP_001732481.1 CDS yicE NC_010473.1 3924552 3925943 D transporter 3924552..3925943 Escherichia coli str. K-12 substr. DH10B 6060253 YP_001732482.1 CDS yicH NC_010473.1 3926064 3927773 D hypothetical protein 3926064..3927773 Escherichia coli str. K-12 substr. DH10B 6060261 YP_001732483.1 CDS yicI NC_010473.1 3927826 3930144 R catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase complement(3927826..3930144) Escherichia coli str. K-12 substr. DH10B 6058309 YP_001732484.1 CDS yicJ NC_010473.1 3930154 3931536 R may be involved in the transport of galactosides-pentoses-hexuronides; putative transporter complement(3930154..3931536) Escherichia coli str. K-12 substr. DH10B 6060272 YP_001732485.1 CDS setC NC_010473.1 3932560 3933744 D sugar efflux system 3932560..3933744 Escherichia coli str. K-12 substr. DH10B 6058754 YP_001732486.1 CDS yicL NC_010473.1 3933855 3934778 D inner membrane protein 3933855..3934778 Escherichia coli str. K-12 substr. DH10B 6058249 YP_001732487.1 CDS nlpA NC_010473.1 3934782 3935600 R hypothetical protein complement(3934782..3935600) Escherichia coli str. K-12 substr. DH10B 6058180 YP_001732488.1 CDS yicS NC_010473.1 3935822 3936115 D hypothetical protein 3935822..3936115 Escherichia coli str. K-12 substr. DH10B 6060315 YP_001732489.1 CDS nepI NC_010473.1 3936156 3937511 R experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS; ribonucleoside transporter complement(3936156..3937511) Escherichia coli str. K-12 substr. DH10B 6058456 YP_001732490.1 CDS yicN NC_010473.1 3937557 3938009 R hypothetical protein complement(3937557..3938009) Escherichia coli str. K-12 substr. DH10B 6060083 YP_001732491.1 CDS yicO NC_010473.1 3938062 3939396 R xanthine/uracil permase complement(3938062..3939396) Escherichia coli str. K-12 substr. DH10B 6060354 YP_001732492.1 CDS ade NC_010473.1 3939571 3941337 D catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 3939571..3941337 Escherichia coli str. K-12 substr. DH10B 6058437 YP_001732493.1 CDS uhpT NC_010473.1 3941383 3942774 R cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter complement(3941383..3942774) Escherichia coli str. K-12 substr. DH10B 6058170 YP_001732494.1 CDS uhpC NC_010473.1 3942912 3944231 R membrane protein regulates uhpT expression; regulatory protein UhpC complement(3942912..3944231) Escherichia coli str. K-12 substr. DH10B 6059157 YP_001732495.1 CDS uhpB NC_010473.1 3944241 3945743 R Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB complement(3944241..3945743) Escherichia coli str. K-12 substr. DH10B 6061098 YP_001732496.1 CDS uhpA NC_010473.1 3945743 3946333 R response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA complement(3945743..3946333) Escherichia coli str. K-12 substr. DH10B 6058657 YP_001732497.1 CDS ilvN NC_010473.1 3946409 3946699 R with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit complement(3946409..3946699) Escherichia coli str. K-12 substr. DH10B 6058378 YP_001732498.1 CDS ilvB NC_010473.1 3946703 3948391 R acetolactate synthase catalytic subunit complement(3946703..3948391) Escherichia coli str. K-12 substr. DH10B 6058513 YP_001732499.1 CDS ivbL NC_010473.1 3948497 3948595 R ilvB operon leader peptide complement(3948497..3948595) Escherichia coli str. K-12 substr. DH10B 6059349 YP_001732500.1 CDS emrD NC_010473.1 3949529 3950713 D multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 3949529..3950713 Escherichia coli str. K-12 substr. DH10B 6058645 YP_001732501.1 CDS yidF NC_010473.1 3950721 3951218 R DNA-binding transcriptional regulator complement(3950721..3951218) Escherichia coli str. K-12 substr. DH10B 6062063 YP_001732502.1 CDS yidG NC_010473.1 3951215 3951577 R inner membrane protein complement(3951215..3951577) Escherichia coli str. K-12 substr. DH10B 6061687 YP_001732503.1 CDS yidH NC_010473.1 3951567 3951914 R inner membrane protein complement(3951567..3951914) Escherichia coli str. K-12 substr. DH10B 6061546 YP_001732504.1 CDS yidI NC_010473.1 3952022 3952471 D inner membrane protein 3952022..3952471 Escherichia coli str. K-12 substr. DH10B 6061398 YP_001732505.1 CDS yidJ NC_010473.1 3952518 3954011 R sulfatase/phosphatase complement(3952518..3954011) Escherichia coli str. K-12 substr. DH10B 6061255 YP_001732506.1 CDS yidK NC_010473.1 3954008 3955723 R uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function; putative symporter YidK complement(3954008..3955723) Escherichia coli str. K-12 substr. DH10B 6061057 YP_001732507.1 CDS yidL NC_010473.1 3955860 3956783 D DNA-binding transcriptional regulator 3955860..3956783 Escherichia coli str. K-12 substr. DH10B 6060904 YP_001732508.1 CDS yidP NC_010473.1 3959506 3960222 D DNA-binding transcriptional regulator 3959506..3960222 Escherichia coli str. K-12 substr. DH10B 6058840 YP_001732509.1 CDS yidE NC_010473.1 3960219 3961880 R hypothetical protein complement(3960219..3961880) Escherichia coli str. K-12 substr. DH10B 6062125 YP_001732510.1 CDS ibpB NC_010473.1 3962076 3962504 R 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB complement(3962076..3962504) Escherichia coli str. K-12 substr. DH10B 6062047 YP_001732511.1 CDS ibpA NC_010473.1 3962616 3963029 R with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA complement(3962616..3963029) Escherichia coli str. K-12 substr. DH10B 6062008 YP_001732512.1 CDS yidQ NC_010473.1 3963335 3963667 D hypothetical protein 3963335..3963667 Escherichia coli str. K-12 substr. DH10B 6061977 YP_001732513.1 CDS yidR NC_010473.1 3963669 3964883 R hypothetical protein complement(3963669..3964883) Escherichia coli str. K-12 substr. DH10B 6061528 YP_001732514.1 CDS dgoT NC_010473.1 3966045 3967337 R D-galactonate transporter complement(3966045..3967337) Escherichia coli str. K-12 substr. DH10B 6061550 YP_001732515.1 CDS dgoD NC_010473.1 3967457 3968605 R galactonate dehydratase complement(3967457..3968605) Escherichia coli str. K-12 substr. DH10B 6061660 YP_001732516.1 CDS dgoA NC_010473.1 3968602 3969219 R catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase complement(3968602..3969219) Escherichia coli str. K-12 substr. DH10B 6061779 YP_001732517.1 CDS dgoK NC_010473.1 3969203 3970081 R 2-oxo-3-deoxygalactonate kinase complement(3969203..3970081) Escherichia coli str. K-12 substr. DH10B 6061402 YP_001732518.1 CDS dgoR NC_010473.1 3970078 3970767 R DNA-binding transcriptional regulator complement(3970078..3970767) Escherichia coli str. K-12 substr. DH10B 6061794 YP_001732519.1 CDS yidX NC_010473.1 3971045 3971701 D hypothetical protein 3971045..3971701 Escherichia coli str. K-12 substr. DH10B 6061922 YP_001732520.1 CDS yidA NC_010473.1 3971747 3972559 R YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase complement(3971747..3972559) Escherichia coli str. K-12 substr. DH10B 6059176 YP_001732521.1 CDS yidB NC_010473.1 3972674 3973072 R hypothetical protein complement(3972674..3973072) Escherichia coli str. K-12 substr. DH10B 6059300 YP_001732522.1 CDS recF NC_010473.1 3975755 3976828 R Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F complement(3975755..3976828) Escherichia coli str. K-12 substr. DH10B 6059269 YP_001732523.1 CDS dnaN NC_010473.1 3976828 3977928 R binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta complement(3976828..3977928) Escherichia coli str. K-12 substr. DH10B 6058510 YP_001732524.1 CDS rpmH NC_010473.1 3979943 3980083 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 3979943..3980083 Escherichia coli str. K-12 substr. DH10B 6058237 YP_001732525.1 CDS rnpA NC_010473.1 3980100 3980459 D protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 3980100..3980459 Escherichia coli str. K-12 substr. DH10B 6059155 YP_001732526.1 CDS yidD NC_010473.1 3980423 3980680 D hypothetical protein 3980423..3980680 Escherichia coli str. K-12 substr. DH10B 6059086 YP_001732527.1 CDS yidC NC_010473.1 3980683 3982329 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC 3980683..3982329 Escherichia coli str. K-12 substr. DH10B 6059018 YP_001732528.1 CDS trmE NC_010473.1 3982435 3983799 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 3982435..3983799 Escherichia coli str. K-12 substr. DH10B 6058961 YP_001732529.1 CDS tnaC NC_010473.1 3984042 3984116 D tryptophanase leader peptide 3984042..3984116 Escherichia coli str. K-12 substr. DH10B 6058912 YP_001732530.1 CDS tnaA NC_010473.1 3984337 3985752 D tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 3984337..3985752 Escherichia coli str. K-12 substr. DH10B 6061034 YP_001732531.1 CDS tnaB NC_010473.1 3985843 3987090 D tryptophan transporter of low affinity; tryptophan permease TnaB 3985843..3987090 Escherichia coli str. K-12 substr. DH10B 6058748 YP_001732532.1 CDS mdtL NC_010473.1 3987222 3988397 D Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 3987222..3988397 Escherichia coli str. K-12 substr. DH10B 6058706 YP_001732533.1 CDS yidZ NC_010473.1 3988372 3989331 D Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 3988372..3989331 Escherichia coli str. K-12 substr. DH10B 6058646 YP_001732534.1 CDS yieE NC_010473.1 3989476 3990237 D phosphopantetheinyl transferase 3989476..3990237 Escherichia coli str. K-12 substr. DH10B 6058098 YP_001732535.1 CDS yieF NC_010473.1 3990259 3990825 D chromate reductase, class I, flavoprotein 3990259..3990825 Escherichia coli str. K-12 substr. DH10B 6058522 YP_001732536.1 CDS yieG NC_010473.1 3990879 3992216 R inner membrane protein complement(3990879..3992216) Escherichia coli str. K-12 substr. DH10B 6058399 YP_001732537.1 CDS yieH NC_010473.1 3992381 3993046 D YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 3992381..3993046 Escherichia coli str. K-12 substr. DH10B 6058461 YP_001732538.1 CDS yieI NC_010473.1 3993113 3993580 D might be involved in hypersensitivity to nitrofurzone; putative inner membrane protein 3993113..3993580 Escherichia coli str. K-12 substr. DH10B 6058116 YP_001732539.1 CDS cbrC NC_010473.1 3993629 3994216 D hypothetical protein 3993629..3994216 Escherichia coli str. K-12 substr. DH10B 6060965 YP_001732540.1 CDS yieK NC_010473.1 3994278 3995000 R putative 6-phosphogluconolactonase complement(3994278..3995000) Escherichia coli str. K-12 substr. DH10B 6062052 YP_001732541.1 CDS yieL NC_010473.1 3995015 3996211 R xylanase complement(3995015..3996211) Escherichia coli str. K-12 substr. DH10B 6061346 YP_001732542.1 CDS bglH NC_010473.1 3996211 3997827 R carbohydrate-specific outer membrane porin, cryptic complement(3996211..3997827) Escherichia coli str. K-12 substr. DH10B 6059326 YP_001732543.1 CDS bglB NC_010473.1 3997896 3999308 R cryptic phospho-beta-glucosidase B complement(3997896..3999308) Escherichia coli str. K-12 substr. DH10B 6061131 YP_001732544.1 CDS bglF NC_010473.1 3999327 4001204 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system beta-glucoside-specific transporter subunit IIABC complement(3999327..4001204) Escherichia coli str. K-12 substr. DH10B 6060435 YP_001732545.1 CDS bglG NC_010473.1 4001338 4002174 R positive regulator of the beta-glucoside operon; transcriptional antiterminator; transcriptional antiterminator BglG complement(4001338..4002174) Escherichia coli str. K-12 substr. DH10B 6060235 YP_001732546.1 CDS phoU NC_010473.1 4002460 4003185 R regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU complement(4002460..4003185) Escherichia coli str. K-12 substr. DH10B 6060084 YP_001732547.1 CDS pstB NC_010473.1 4003200 4003973 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(4003200..4003973) Escherichia coli str. K-12 substr. DH10B 6058315 YP_001732548.1 CDS pstA NC_010473.1 4004156 4005046 R Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA complement(4004156..4005046) Escherichia coli str. K-12 substr. DH10B 6058228 YP_001732549.1 CDS pstC NC_010473.1 4005046 4006005 R part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC complement(4005046..4006005) Escherichia coli str. K-12 substr. DH10B 6058429 YP_001732550.1 CDS pstS NC_010473.1 4006092 4007132 R phosphate ABC transporter substrate-binding protein complement(4006092..4007132) Escherichia coli str. K-12 substr. DH10B 6060017 YP_001732551.1 CDS glmU NC_010473.1 4009437 4010807 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(4009437..4010807) Escherichia coli str. K-12 substr. DH10B 6059870 YP_001732552.1 CDS atpC NC_010473.1 4011160 4011579 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(4011160..4011579) Escherichia coli str. K-12 substr. DH10B 6062003 YP_001732553.1 CDS atpD NC_010473.1 4011600 4012982 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(4011600..4012982) Escherichia coli str. K-12 substr. DH10B 6058271 YP_001732554.1 CDS atpG NC_010473.1 4013009 4013872 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(4013009..4013872) Escherichia coli str. K-12 substr. DH10B 6059435 YP_001732555.1 CDS atpA NC_010473.1 4013923 4015464 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(4013923..4015464) Escherichia coli str. K-12 substr. DH10B 6060798 YP_001732556.1 CDS atpH NC_010473.1 4015477 4016010 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(4015477..4016010) Escherichia coli str. K-12 substr. DH10B 6061478 YP_001732557.1 CDS atpF NC_010473.1 4016025 4016495 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B complement(4016025..4016495) Escherichia coli str. K-12 substr. DH10B 6060491 YP_001732558.1 CDS atpE NC_010473.1 4016557 4016796 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C complement(4016557..4016796) Escherichia coli str. K-12 substr. DH10B 6061741 YP_001732559.1 CDS atpB NC_010473.1 4016843 4017658 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(4016843..4017658) Escherichia coli str. K-12 substr. DH10B 6060643 YP_001732560.1 CDS atpI NC_010473.1 4017667 4018047 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I complement(4017667..4018047) Escherichia coli str. K-12 substr. DH10B 6060503 YP_001732561.1 CDS gidB NC_010473.1 4018664 4019287 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(4018664..4019287) Escherichia coli str. K-12 substr. DH10B 6060614 YP_001732562.1 CDS gidA NC_010473.1 4019351 4021240 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(4019351..4021240) Escherichia coli str. K-12 substr. DH10B 6058463 YP_001732563.1 CDS mioC NC_010473.1 4021619 4022062 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(4021619..4022062) Escherichia coli str. K-12 substr. DH10B 6061156 YP_001732564.1 CDS asnC NC_010473.1 4022152 4022610 R transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC complement(4022152..4022610) Escherichia coli str. K-12 substr. DH10B 6058775 YP_001732565.1 CDS asnA NC_010473.1 4022762 4023754 D catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4022762..4023754 Escherichia coli str. K-12 substr. DH10B 6060092 YP_001732566.1 CDS yieM NC_010473.1 4023759 4025210 R contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein complement(4023759..4025210) Escherichia coli str. K-12 substr. DH10B 6058504 YP_001732567.1 CDS trkD NC_010473.1 4026923 4028791 D Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4026923..4028791 Escherichia coli str. K-12 substr. DH10B 6060369 YP_001732568.1 CDS rbsD NC_010473.1 4028958 4029377 D cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4028958..4029377 Escherichia coli str. K-12 substr. DH10B 6058554 YP_001732569.1 CDS rbsA NC_010473.1 4029385 4030890 D with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP-binding protein 4029385..4030890 Escherichia coli str. K-12 substr. DH10B 6058276 YP_001732570.1 CDS rbsC NC_010473.1 4030895 4031860 D functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 4030895..4031860 Escherichia coli str. K-12 substr. DH10B 6058219 YP_001732571.1 CDS rbsB NC_010473.1 4031885 4032775 D periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4031885..4032775 Escherichia coli str. K-12 substr. DH10B 6059788 YP_001732572.1 CDS rbsK NC_010473.1 4032901 4033830 D catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4032901..4033830 Escherichia coli str. K-12 substr. DH10B 6061440 YP_001732573.1 CDS hsrA NC_010473.1 4036128 4037555 R multidrug or homocysteine efflux system complement(4036128..4037555) Escherichia coli str. K-12 substr. DH10B 6061408 YP_001732574.1 CDS yieP NC_010473.1 4037578 4038270 R transcriptional regulator complement(4037578..4038270) Escherichia coli str. K-12 substr. DH10B 6058774 YP_001732575.1 CDS hdfR NC_010473.1 4044071 4044910 R Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR complement(4044071..4044910) Escherichia coli str. K-12 substr. DH10B 6061021 YP_001732576.1 CDS yifE NC_010473.1 4045029 4045367 D hypothetical protein 4045029..4045367 Escherichia coli str. K-12 substr. DH10B 6060651 YP_001732577.1 CDS yifB NC_010473.1 4045392 4046942 R among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function; putative ATP-dependent protease complement(4045392..4046942) Escherichia coli str. K-12 substr. DH10B 6058459 YP_001732578.1 CDS ilvL NC_010473.1 4047265 4047363 D ilvG operon leader peptide 4047265..4047363 Escherichia coli str. K-12 substr. DH10B 6058561 YP_001732579.1 CDS ilvM NC_010473.1 4049144 4049407 D acetolactate synthase 2 regulatory subunit 4049144..4049407 Escherichia coli str. K-12 substr. DH10B 6058436 YP_001732580.1 CDS ilvE NC_010473.1 4049427 4050356 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4049427..4050356 Escherichia coli str. K-12 substr. DH10B 6058370 YP_001732581.1 CDS ilvA NC_010473.1 4052274 4053818 D threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 4052274..4053818 Escherichia coli str. K-12 substr. DH10B 6058988 YP_001732582.1 CDS ilvY NC_010473.1 4053870 4054763 R participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY complement(4053870..4054763) Escherichia coli str. K-12 substr. DH10B 6059375 YP_001732583.1 CDS ilvC NC_010473.1 4054913 4056388 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 4054913..4056388 Escherichia coli str. K-12 substr. DH10B 6059704 YP_001732584.1 CDS ppiC NC_010473.1 4056475 4056756 R peptidyl-prolyl cis-trans isomerase C complement(4056475..4056756) Escherichia coli str. K-12 substr. DH10B 6062187 YP_001732585.1 CDS rep NC_010473.1 4057620 4059641 D single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 4057620..4059641 Escherichia coli str. K-12 substr. DH10B 6059691 YP_001732586.1 CDS gpp NC_010473.1 4059688 4061172 R catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase complement(4059688..4061172) Escherichia coli str. K-12 substr. DH10B 6061985 YP_001732587.1 CDS rhlB NC_010473.1 4061308 4062573 R enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB complement(4061308..4062573) Escherichia coli str. K-12 substr. DH10B 6061836 YP_001732588.1 CDS trxA NC_010473.1 4062704 4063033 D thioredoxin 4062704..4063033 Escherichia coli str. K-12 substr. DH10B 6061668 YP_001732589.1 CDS rhoL NC_010473.1 4063174 4063275 D putative rho operon leader peptide 4063174..4063275 Escherichia coli str. K-12 substr. DH10B 6061627 YP_001732590.1 CDS rho NC_010473.1 4063360 4064619 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 4063360..4064619 Escherichia coli str. K-12 substr. DH10B 6061516 YP_001732591.1 CDS rfe NC_010473.1 4064859 4065962 D undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase 4064859..4065962 Escherichia coli str. K-12 substr. DH10B 6061498 YP_001732592.1 CDS wzzE NC_010473.1 4065974 4067020 D Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 4065974..4067020 Escherichia coli str. K-12 substr. DH10B 6061323 YP_001732593.1 CDS rffE NC_010473.1 4067076 4068206 D UDP-N-acetylglucosamine 2-epimerase 4067076..4068206 Escherichia coli str. K-12 substr. DH10B 6061290 YP_001732594.1 CDS wecC NC_010473.1 4068203 4069465 D catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 4068203..4069465 Escherichia coli str. K-12 substr. DH10B 6061175 YP_001732595.1 CDS rffG NC_010473.1 4069465 4070532 D dTDP-glucose 4,6-dehydratase 4069465..4070532 Escherichia coli str. K-12 substr. DH10B 6061151 YP_001732596.1 CDS rffH NC_010473.1 4070551 4071432 D glucose-1-phosphate thymidylyltransferase 4070551..4071432 Escherichia coli str. K-12 substr. DH10B 6061020 YP_001732597.1 CDS rffC NC_010473.1 4071410 4072084 D TDP-fucosamine acetyltransferase 4071410..4072084 Escherichia coli str. K-12 substr. DH10B 6060940 YP_001732598.1 CDS rffA NC_010473.1 4072089 4073219 D catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 4072089..4073219 Escherichia coli str. K-12 substr. DH10B 6060889 YP_001732599.1 CDS wzxE NC_010473.1 4073221 4074471 D lipid III translocase 4073221..4074471 Escherichia coli str. K-12 substr. DH10B 6060806 YP_001732600.1 CDS rffT NC_010473.1 4074468 4075547 D catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 4074468..4075547 Escherichia coli str. K-12 substr. DH10B 6060579 YP_001732601.1 CDS wzyE NC_010473.1 4075544 4076896 D enterobacterial common antigen polymerase; putative common antigen polymerase 4075544..4076896 Escherichia coli str. K-12 substr. DH10B 6060539 YP_001732602.1 CDS rffM NC_010473.1 4076899 4077639 D putative UDP-N-acetyl-D-mannosaminuronic acid transferase 4076899..4077639 Escherichia coli str. K-12 substr. DH10B 6061124 YP_001732603.1 CDS yifK NC_010473.1 4077830 4079215 D uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; putative transport protein YifK 4077830..4079215 Escherichia coli str. K-12 substr. DH10B 6061103 YP_001732604.1 CDS aslB NC_010473.1 4079901 4081136 D regulator of arylsulfatase activity 4079901..4081136 Escherichia coli str. K-12 substr. DH10B 6060540 YP_001732605.1 CDS aslA NC_010473.1 4081295 4082950 R acrylsulfatase-like protein complement(4081295..4082950) Escherichia coli str. K-12 substr. DH10B 6061059 YP_001732606.1 CDS hemY NC_010473.1 4083629 4084825 R putative protoheme IX biogenesis protein complement(4083629..4084825) Escherichia coli str. K-12 substr. DH10B 6061393 YP_001732607.1 CDS hemD NC_010473.1 4086031 4086771 R catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase complement(4086031..4086771) Escherichia coli str. K-12 substr. DH10B 6060968 YP_001732608.1 CDS hemC NC_010473.1 4086768 4087709 R transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase complement(4086768..4087709) Escherichia coli str. K-12 substr. DH10B 6060627 YP_001732609.1 CDS cyaY NC_010473.1 4090682 4091002 R defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein complement(4090682..4091002) Escherichia coli str. K-12 substr. DH10B 6060988 YP_001732610.1 CDS yzcX NC_010473.1 4090793 4091278 D hypothetical protein 4090793..4091278 Escherichia coli str. K-12 substr. DH10B 6061750 YP_001732611.1 CDS yifL NC_010473.1 4091465 4091668 D lipoprotein 4091465..4091668 Escherichia coli str. K-12 substr. DH10B 6061632 YP_001732612.1 CDS dapF NC_010473.1 4091705 4092529 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 4091705..4092529 Escherichia coli str. K-12 substr. DH10B 6061568 YP_001732613.1 CDS xerC NC_010473.1 4093230 4094126 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 4093230..4094126 Escherichia coli str. K-12 substr. DH10B 6060597 YP_001732614.1 CDS yigB NC_010473.1 4094126 4094842 D YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 4094126..4094842 Escherichia coli str. K-12 substr. DH10B 6060825 YP_001732615.1 CDS uvrD NC_010473.1 4094926 4097088 D unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 4094926..4097088 Escherichia coli str. K-12 substr. DH10B 6061671 YP_001732616.1 CDS yigE NC_010473.1 4097235 4097999 R hypothetical protein complement(4097235..4097999) Escherichia coli str. K-12 substr. DH10B 6060916 YP_001732617.1 CDS corA NC_010473.1 4098369 4099319 D responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 4098369..4099319 Escherichia coli str. K-12 substr. DH10B 6061869 YP_001732618.1 CDS yigF NC_010473.1 4099362 4099742 R inner membrane protein complement(4099362..4099742) Escherichia coli str. K-12 substr. DH10B 6061482 YP_001732619.1 CDS yigG NC_010473.1 4099756 4100136 R hypothetical protein complement(4099756..4100136) Escherichia coli str. K-12 substr. DH10B 6060721 YP_001732620.1 CDS rarD NC_010473.1 4100231 4101121 R chloramphenical resistance permease complement(4100231..4101121) Escherichia coli str. K-12 substr. DH10B 6060866 YP_001732621.1 CDS yigI NC_010473.1 4101173 4101640 R hypothetical protein complement(4101173..4101640) Escherichia coli str. K-12 substr. DH10B 6060944 YP_001732622.1 CDS pldA NC_010473.1 4101805 4102674 D catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 4101805..4102674 Escherichia coli str. K-12 substr. DH10B 6058105 YP_001732623.1 CDS recQ NC_010473.1 4102807 4104636 D functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 4102807..4104636 Escherichia coli str. K-12 substr. DH10B 6059482 YP_001732624.1 CDS rhtC NC_010473.1 4104700 4105320 D threonine efflux system 4104700..4105320 Escherichia coli str. K-12 substr. DH10B 6061914 YP_001732625.1 CDS rhtB NC_010473.1 4105382 4106002 R homoserine/homoserine lactone efflux protein complement(4105382..4106002) Escherichia coli str. K-12 substr. DH10B 6059312 YP_001732626.1 CDS pldB NC_010473.1 4106113 4107135 D lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 4106113..4107135 Escherichia coli str. K-12 substr. DH10B 6059297 YP_001732627.1 CDS yigL NC_010473.1 4107143 4107943 D purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; putative sugar phosphatase 4107143..4107943 Escherichia coli str. K-12 substr. DH10B 6059290 YP_001732628.1 CDS metR NC_010473.1 4108806 4109759 R DNA-binding transcriptional activator, homocysteine-binding complement(4108806..4109759) Escherichia coli str. K-12 substr. DH10B 6059225 YP_001732629.1 CDS metE NC_010473.1 4109996 4112257 D catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 4109996..4112257 Escherichia coli str. K-12 substr. DH10B 6059211 YP_001732630.1 CDS ysgA NC_010473.1 4112297 4113112 R hydrolase complement(4112297..4113112) Escherichia coli str. K-12 substr. DH10B 6058274 YP_001732631.1 CDS udp NC_010473.1 4113374 4114135 D catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 4113374..4114135 Escherichia coli str. K-12 substr. DH10B 6062352 YP_001732632.1 CDS rmuC NC_010473.1 4114276 4115703 D YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 4114276..4115703 Escherichia coli str. K-12 substr. DH10B 6058334 YP_001732633.1 CDS ubiE NC_010473.1 4115798 4116553 D Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4115798..4116553 Escherichia coli str. K-12 substr. DH10B 6060314 YP_001732634.1 CDS yigP NC_010473.1 4116567 4117172 D hypothetical protein 4116567..4117172 Escherichia coli str. K-12 substr. DH10B 6059141 YP_001732635.1 CDS ubiB NC_010473.1 4117169 4118809 D an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; putative ubiquinone biosynthesis protein UbiB 4117169..4118809 Escherichia coli str. K-12 substr. DH10B 6059192 YP_001732636.1 CDS tatA NC_010473.1 4118888 4119157 D TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 4118888..4119157 Escherichia coli str. K-12 substr. DH10B 6059162 YP_001732637.1 CDS tatB NC_010473.1 4119161 4119676 D mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 4119161..4119676 Escherichia coli str. K-12 substr. DH10B 6060545 YP_001732638.1 CDS tatC NC_010473.1 4119679 4120455 D with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 4119679..4120455 Escherichia coli str. K-12 substr. DH10B 6059036 YP_001732639.1 CDS tatD NC_010473.1 4120497 4121279 D magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 4120497..4121279 Escherichia coli str. K-12 substr. DH10B 6059048 YP_001732640.1 CDS rfaH NC_010473.1 4121276 4121764 R transcriptional activator RfaH complement(4121276..4121764) Escherichia coli str. K-12 substr. DH10B 6058984 YP_001732641.1 CDS ubiD NC_010473.1 4121931 4123424 D catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 4121931..4123424 Escherichia coli str. K-12 substr. DH10B 6059020 YP_001732642.1 CDS fre NC_010473.1 4123470 4124171 D NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 4123470..4124171 Escherichia coli str. K-12 substr. DH10B 6061282 YP_001732643.1 CDS fadA NC_010473.1 4124552 4125715 R FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase complement(4124552..4125715) Escherichia coli str. K-12 substr. DH10B 6061185 YP_001732644.1 CDS fadB NC_010473.1 4125725 4127914 R includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha complement(4125725..4127914) Escherichia coli str. K-12 substr. DH10B 6058879 YP_001732645.1 CDS pepQ NC_010473.1 4128104 4129435 D catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 4128104..4129435 Escherichia coli str. K-12 substr. DH10B 6061092 YP_001732646.1 CDS yigZ NC_010473.1 4129435 4130049 D hypothetical protein 4129435..4130049 Escherichia coli str. K-12 substr. DH10B 6058801 YP_001732647.1 CDS trkH NC_010473.1 4130088 4131539 D potassium transporter 4130088..4131539 Escherichia coli str. K-12 substr. DH10B 6058816 YP_001732648.1 CDS hemG NC_010473.1 4131551 4132096 D catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 4131551..4132096 Escherichia coli str. K-12 substr. DH10B 6058727 YP_001732649.1 CDS mobB NC_010473.1 4137849 4138361 R in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein B complement(4137849..4138361) Escherichia coli str. K-12 substr. DH10B 6060868 YP_001732650.1 CDS mobA NC_010473.1 4138358 4138942 R in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA complement(4138358..4138942) Escherichia coli str. K-12 substr. DH10B 6058667 YP_001732651.1 CDS yihD NC_010473.1 4139012 4139281 D hypothetical protein 4139012..4139281 Escherichia coli str. K-12 substr. DH10B 6058671 YP_001732652.1 CDS yihE NC_010473.1 4139358 4140344 D catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 4139358..4140344 Escherichia coli str. K-12 substr. DH10B 6058523 YP_001732653.1 CDS dsbA NC_010473.1 4140361 4140987 D protein disulfide isomerase I 4140361..4140987 Escherichia coli str. K-12 substr. DH10B 6058256 YP_001732654.1 CDS yihF NC_010473.1 4141142 4142572 D hypothetical protein 4141142..4142572 Escherichia coli str. K-12 substr. DH10B 6058337 YP_001732655.1 CDS yihG NC_010473.1 4142613 4143545 R putative acyltransferase complement(4142613..4143545) Escherichia coli str. K-12 substr. DH10B 6058383 YP_001732656.1 CDS polA NC_010473.1 4143909 4146695 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 4143909..4146695 Escherichia coli str. K-12 substr. DH10B 6058570 YP_001732657.1 CDS engB NC_010473.1 4147076 4147672 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(4147076..4147672) Escherichia coli str. K-12 substr. DH10B 6061913 YP_001732658.1 CDS yihI NC_010473.1 4148290 4148799 D hypothetical protein 4148290..4148799 Escherichia coli str. K-12 substr. DH10B 6061025 YP_001732659.1 CDS hemN NC_010473.1 4148988 4150361 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 4148988..4150361 Escherichia coli str. K-12 substr. DH10B 6058495 YP_001732660.1 CDS glnG NC_010473.1 4150812 4152221 R response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) complement(4150812..4152221) Escherichia coli str. K-12 substr. DH10B 6058394 YP_001732661.1 CDS glnL NC_010473.1 4152233 4153282 R sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) complement(4152233..4153282) Escherichia coli str. K-12 substr. DH10B 6058188 YP_001732662.1 CDS glnA NC_010473.1 4153568 4154977 R forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase complement(4153568..4154977) Escherichia coli str. K-12 substr. DH10B 6060875 YP_001732663.1 CDS bipA NC_010473.1 4155350 4157173 D GTP-binding protein 4155350..4157173 Escherichia coli str. K-12 substr. DH10B 6062333 YP_001732664.1 CDS yihL NC_010473.1 4157390 4158100 D DNA-binding transcriptional regulator 4157390..4158100 Escherichia coli str. K-12 substr. DH10B 6059605 YP_001732665.1 CDS yihM NC_010473.1 4158108 4159088 D sugar phosphate isomerase 4158108..4159088 Escherichia coli str. K-12 substr. DH10B 6059523 YP_001732666.1 CDS yihN NC_010473.1 4159190 4160455 D transporter 4159190..4160455 Escherichia coli str. K-12 substr. DH10B 6059512 YP_001732667.1 CDS ompL NC_010473.1 4160546 4161238 R porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown; outer membrane porin L complement(4160546..4161238) Escherichia coli str. K-12 substr. DH10B 6059379 YP_001732668.1 CDS yihO NC_010473.1 4161306 4162709 R predited transporter complement(4161306..4162709) Escherichia coli str. K-12 substr. DH10B 6059917 YP_001732669.1 CDS yihP NC_010473.1 4162752 4164158 R transporter complement(4162752..4164158) Escherichia coli str. K-12 substr. DH10B 6059922 YP_001732670.1 CDS yihQ NC_010473.1 4164183 4166219 R alpha-glucosidase complement(4164183..4166219) Escherichia coli str. K-12 substr. DH10B 6059929 YP_001732671.1 CDS yihR NC_010473.1 4167195 4168121 R aldose-1-epimerase complement(4167195..4168121) Escherichia coli str. K-12 substr. DH10B 6060355 YP_001732672.1 CDS yihS NC_010473.1 4168235 4169476 R glucosamine isomerase complement(4168235..4169476) Escherichia coli str. K-12 substr. DH10B 6060381 YP_001732673.1 CDS yihT NC_010473.1 4169493 4170371 R aldolase complement(4169493..4170371) Escherichia coli str. K-12 substr. DH10B 6060488 YP_001732674.1 CDS yihU NC_010473.1 4170395 4171291 R oxidoreductase complement(4170395..4171291) Escherichia coli str. K-12 substr. DH10B 6062301 YP_001732675.1 CDS yihV NC_010473.1 4171459 4172355 D sugar kinase 4171459..4172355 Escherichia coli str. K-12 substr. DH10B 6062329 YP_001732676.1 CDS yihW NC_010473.1 4172389 4173174 D DNA-binding transcriptional regulator 4172389..4173174 Escherichia coli str. K-12 substr. DH10B 6062343 YP_001732677.1 CDS yihX NC_010473.1 4173273 4173872 D phosphatase 4173273..4173872 Escherichia coli str. K-12 substr. DH10B 6062399 YP_001732678.1 CDS rbn NC_010473.1 4173866 4174738 D RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 4173866..4174738 Escherichia coli str. K-12 substr. DH10B 6060471 YP_001732679.1 CDS dtd NC_010473.1 4174735 4175172 D hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 4174735..4175172 Escherichia coli str. K-12 substr. DH10B 6058978 YP_001732680.1 CDS yiiD NC_010473.1 4175169 4176158 D acetyltransferase 4175169..4176158 Escherichia coli str. K-12 substr. DH10B 6059471 YP_001732681.1 CDS yiiE NC_010473.1 4177011 4177229 D transcriptional regulator 4177011..4177229 Escherichia coli str. K-12 substr. DH10B 6058472 YP_001732682.1 CDS yiiF NC_010473.1 4177471 4177689 D hypothetical protein 4177471..4177689 Escherichia coli str. K-12 substr. DH10B 6058590 YP_001732683.1 CDS fdhE NC_010473.1 4178019 4178948 R required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE complement(4178019..4178948) Escherichia coli str. K-12 substr. DH10B 6060040 YP_001732684.1 CDS fdoI NC_010473.1 4178945 4179580 R cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma complement(4178945..4179580) Escherichia coli str. K-12 substr. DH10B 6059355 YP_001732685.1 CDS fdoH NC_010473.1 4179577 4180479 R formate dehydrogenase-O, Fe-S subunit complement(4179577..4180479) Escherichia coli str. K-12 substr. DH10B 6059184 YP_001732686.1 CDS fdoG NC_010473.1 4180492 4183542 R contains the nonsynonymous change N307T; formate dehydrogenase-O, large subunit complement(4180492..4183542) Escherichia coli str. K-12 substr. DH10B 6061545 YP_001732687.1 CDS fdhD NC_010473.1 4183736 4184569 D involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 4183736..4184569 Escherichia coli str. K-12 substr. DH10B 6061431 YP_001732688.1 CDS yiiG NC_010473.1 4184722 4185777 D hypothetical protein 4184722..4185777 Escherichia coli str. K-12 substr. DH10B 6061296 YP_001732689.1 CDS frvR NC_010473.1 4185827 4187575 R putative repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system; putative frv operon regulatory protein complement(4185827..4187575) Escherichia coli str. K-12 substr. DH10B 6061300 YP_001732690.1 CDS frvX NC_010473.1 4187575 4188645 R with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars; putative fructose-specific phosphotransferase system protein FrvX complement(4187575..4188645) Escherichia coli str. K-12 substr. DH10B 6061305 YP_001732691.1 CDS frvB NC_010473.1 4188635 4190086 R putative PTS system transporter subunits IIBC complement(4188635..4190086) Escherichia coli str. K-12 substr. DH10B 6061352 YP_001732692.1 CDS yiiL NC_010473.1 4190844 4191158 R L-rhamnose mutarotase complement(4190844..4191158) Escherichia coli str. K-12 substr. DH10B 6061273 YP_001732693.1 CDS rhaD NC_010473.1 4191168 4191992 R rhamnulose-1-phosphate aldolase complement(4191168..4191992) Escherichia coli str. K-12 substr. DH10B 6062228 YP_001732694.1 CDS rhaA NC_010473.1 4192443 4193702 R catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase complement(4192443..4193702) Escherichia coli str. K-12 substr. DH10B 6061366 YP_001732695.1 CDS rhaB NC_010473.1 4193699 4195168 R catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase complement(4193699..4195168) Escherichia coli str. K-12 substr. DH10B 6060283 YP_001732696.1 CDS rhaS NC_010473.1 4195456 4196292 D activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 4195456..4196292 Escherichia coli str. K-12 substr. DH10B 6061198 YP_001732697.1 CDS rhaR NC_010473.1 4196276 4197214 D activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 4196276..4197214 Escherichia coli str. K-12 substr. DH10B 6060647 YP_001732698.1 CDS rhaT NC_010473.1 4197211 4198245 R transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter complement(4197211..4198245) Escherichia coli str. K-12 substr. DH10B 6061304 YP_001732699.1 CDS sodA NC_010473.1 4198530 4199150 D SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 4198530..4199150 Escherichia coli str. K-12 substr. DH10B 6061123 YP_001732700.1 CDS kdgT NC_010473.1 4199410 4200393 D transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 4199410..4200393 Escherichia coli str. K-12 substr. DH10B 6061277 YP_001732701.1 CDS yiiM NC_010473.1 4200542 4201216 D hypothetical protein 4200542..4201216 Escherichia coli str. K-12 substr. DH10B 6062328 YP_001732702.1 CDS cpxA NC_010473.1 4201322 4202695 R part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein complement(4201322..4202695) Escherichia coli str. K-12 substr. DH10B 6061327 YP_001732703.1 CDS cpxR NC_010473.1 4202692 4203390 R response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR complement(4202692..4203390) Escherichia coli str. K-12 substr. DH10B 6060728 YP_001732704.1 CDS cpxP NC_010473.1 4203540 4204040 D repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; repressor CpxP 4203540..4204040 Escherichia coli str. K-12 substr. DH10B 6060639 YP_001732705.1 CDS fieF NC_010473.1 4204189 4205091 D member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 4204189..4205091 Escherichia coli str. K-12 substr. DH10B 6062238 YP_001732706.1 CDS pfkA NC_010473.1 4205272 4206234 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 4205272..4206234 Escherichia coli str. K-12 substr. DH10B 6059835 YP_001732707.1 CDS sbp NC_010473.1 4206554 4207543 D sulfate transporter subunit 4206554..4207543 Escherichia coli str. K-12 substr. DH10B 6061263 YP_001732708.1 CDS cdh NC_010473.1 4207650 4208405 D CDP-diacylglycerol pyrophosphatase 4207650..4208405 Escherichia coli str. K-12 substr. DH10B 6060708 YP_001732709.1 CDS tpiA NC_010473.1 4208460 4209227 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(4208460..4209227) Escherichia coli str. K-12 substr. DH10B 6061229 YP_001732710.1 CDS yiiQ NC_010473.1 4209335 4209934 R hypothetical protein complement(4209335..4209934) Escherichia coli str. K-12 substr. DH10B 6061212 YP_001732711.1 CDS yiiR NC_010473.1 4210035 4210475 D inner membrane protein 4210035..4210475 Escherichia coli str. K-12 substr. DH10B 6060966 YP_001732712.1 CDS yiiS NC_010473.1 4210687 4210986 D hypothetical protein 4210687..4210986 Escherichia coli str. K-12 substr. DH10B 6061911 YP_001732713.1 CDS yiiT NC_010473.1 4211013 4211441 D with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 4211013..4211441 Escherichia coli str. K-12 substr. DH10B 6061952 YP_001732714.1 CDS fpr NC_010473.1 4211446 4212192 R ferredoxin-NADP reductase complement(4211446..4212192) Escherichia coli str. K-12 substr. DH10B 6060957 YP_001732715.1 CDS glpX NC_010473.1 4212289 4213299 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(4212289..4213299) Escherichia coli str. K-12 substr. DH10B 6061955 YP_001732716.1 CDS glpK NC_010473.1 4213434 4214942 R Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase complement(4213434..4214942) Escherichia coli str. K-12 substr. DH10B 6062224 YP_001732717.1 CDS glpF NC_010473.1 4214965 4215810 R glycerol facilitator complement(4214965..4215810) Escherichia coli str. K-12 substr. DH10B 6062231 YP_001732718.1 CDS yiiU NC_010473.1 4216235 4216480 D hypothetical protein 4216235..4216480 Escherichia coli str. K-12 substr. DH10B 6062237 YP_001732719.1 CDS rraA NC_010473.1 4216565 4217050 R regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA complement(4216565..4217050) Escherichia coli str. K-12 substr. DH10B 6061221 YP_001732720.1 CDS menA NC_010473.1 4217143 4218069 R catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase complement(4217143..4218069) Escherichia coli str. K-12 substr. DH10B 6061090 YP_001732721.1 CDS hslU NC_010473.1 4218136 4219467 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU complement(4218136..4219467) Escherichia coli str. K-12 substr. DH10B 6061076 YP_001732722.1 CDS hslV NC_010473.1 4219477 4220007 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit complement(4219477..4220007) Escherichia coli str. K-12 substr. DH10B 6062158 YP_001732723.1 CDS ftsN NC_010473.1 4220100 4221059 R cell division protein FtsN complement(4220100..4221059) Escherichia coli str. K-12 substr. DH10B 6060591 YP_001732724.1 CDS cytR NC_010473.1 4221151 4222176 R negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR complement(4221151..4222176) Escherichia coli str. K-12 substr. DH10B 6061022 YP_001732725.1 CDS priA NC_010473.1 4222332 4224530 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(4222332..4224530) Escherichia coli str. K-12 substr. DH10B 6061164 YP_001732726.1 CDS rpmE NC_010473.1 4224733 4224945 D RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 4224733..4224945 Escherichia coli str. K-12 substr. DH10B 6062197 YP_001732727.1 CDS yiiX NC_010473.1 4225006 4225614 R member of the NlpC/P60 superfamily of peptidases; putative peptidoglycan peptidase complement(4225006..4225614) Escherichia coli str. K-12 substr. DH10B 6060550 YP_001732728.1 CDS metJ NC_010473.1 4225798 4226115 R when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ complement(4225798..4226115) Escherichia coli str. K-12 substr. DH10B 6061610 YP_001732729.1 CDS metB NC_010473.1 4226392 4227552 D catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 4226392..4227552 Escherichia coli str. K-12 substr. DH10B 6061056 YP_001732730.1 CDS metL NC_010473.1 4227555 4229987 D multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 4227555..4229987 Escherichia coli str. K-12 substr. DH10B 6061874 YP_001732731.1 CDS metF NC_010473.1 4230336 4231226 D MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 4230336..4231226 Escherichia coli str. K-12 substr. DH10B 6061824 YP_001732732.1 CDS katG NC_010473.1 4231555 4233735 D catalase/hydroperoxidase HPI(I) 4231555..4233735 Escherichia coli str. K-12 substr. DH10B 6062229 YP_001732733.1 CDS yijE NC_010473.1 4233828 4234733 D permease 4233828..4234733 Escherichia coli str. K-12 substr. DH10B 6062134 YP_001732734.1 CDS yijF NC_010473.1 4234760 4235377 R hypothetical protein complement(4234760..4235377) Escherichia coli str. K-12 substr. DH10B 6061946 YP_001732735.1 CDS gldA NC_010473.1 4235652 4236755 R forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase complement(4235652..4236755) Escherichia coli str. K-12 substr. DH10B 6058353 YP_001732736.1 CDS fsaB NC_010473.1 4236766 4237428 R similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase complement(4236766..4237428) Escherichia coli str. K-12 substr. DH10B 6058327 YP_001732737.1 CDS ptsA NC_010473.1 4237440 4239941 R fused PTS enzymes: Hpr component; enzyme I component; enzyme IIA component complement(4237440..4239941) Escherichia coli str. K-12 substr. DH10B 6058379 YP_001732738.1 CDS frwC NC_010473.1 4240250 4241329 D FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; putative fructose-like permease EIIC subunit 2 4240250..4241329 Escherichia coli str. K-12 substr. DH10B 6058449 YP_001732739.1 CDS frwB NC_010473.1 4241344 4241664 D FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; putative PTS system fructose-like transporter subunit EIIB 4241344..4241664 Escherichia coli str. K-12 substr. DH10B 6058526 YP_001732740.1 CDS pflD NC_010473.1 4241715 4244012 D involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; putative formate acetyltransferase 2 4241715..4244012 Escherichia coli str. K-12 substr. DH10B 6058295 YP_001732741.1 CDS pflC NC_010473.1 4243978 4244856 D pyruvate formate lyase II activase 4243978..4244856 Escherichia coli str. K-12 substr. DH10B 6058543 YP_001732742.1 CDS frwD NC_010473.1 4244858 4245199 D FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; putative fructose-like phosphotransferase EIIB subunit 3 4244858..4245199 Escherichia coli str. K-12 substr. DH10B 6058418 YP_001732743.1 CDS yijO NC_010473.1 4245186 4246037 R DNA-binding transcriptional regulator complement(4245186..4246037) Escherichia coli str. K-12 substr. DH10B 6058321 YP_001732744.1 CDS yijP NC_010473.1 4246252 4247985 R hypothetical protein complement(4246252..4247985) Escherichia coli str. K-12 substr. DH10B 6058376 YP_001732745.1 CDS ppc NC_010473.1 4248167 4250818 R catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase complement(4248167..4250818) Escherichia coli str. K-12 substr. DH10B 6058099 YP_001732746.1 CDS argE NC_010473.1 4251416 4252567 R catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase complement(4251416..4252567) Escherichia coli str. K-12 substr. DH10B 6058349 YP_001732747.1 CDS argC NC_010473.1 4252721 4253725 D catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 4252721..4253725 Escherichia coli str. K-12 substr. DH10B 6058303 YP_001732748.1 CDS argB NC_010473.1 4253736 4254509 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 4253736..4254509 Escherichia coli str. K-12 substr. DH10B 6058363 YP_001732749.1 CDS argH NC_010473.1 4254570 4255943 D catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 4254570..4255943 Escherichia coli str. K-12 substr. DH10B 6058290 YP_001732750.1 CDS oxyR NC_010473.1 4256210 4257127 D Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 4256210..4257127 Escherichia coli str. K-12 substr. DH10B 6062039 YP_001732751.1 CDS sthA NC_010473.1 4257110 4258510 R catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase complement(4257110..4258510) Escherichia coli str. K-12 substr. DH10B 6058332 YP_001732752.1 CDS fabR NC_010473.1 4258844 4259491 D negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 4258844..4259491 Escherichia coli str. K-12 substr. DH10B 6058525 YP_001732753.1 CDS yijD NC_010473.1 4259491 4259850 D hypothetical protein 4259491..4259850 Escherichia coli str. K-12 substr. DH10B 6058266 YP_001732754.1 CDS trmA NC_010473.1 4259890 4260990 R catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase complement(4259890..4260990) Escherichia coli str. K-12 substr. DH10B 6062245 YP_001732755.1 CDS btuB NC_010473.1 4261359 4263203 D involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 4261359..4263203 Escherichia coli str. K-12 substr. DH10B 6058457 YP_001732756.1 CDS murI NC_010473.1 4263148 4264005 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 4263148..4264005 Escherichia coli str. K-12 substr. DH10B 6058260 YP_001732757.1 CDS murB NC_010473.1 4269777 4270805 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 4269777..4270805 Escherichia coli str. K-12 substr. DH10B 6061140 YP_001732758.1 CDS birA NC_010473.1 4270802 4271767 D catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 4270802..4271767 Escherichia coli str. K-12 substr. DH10B 6059190 YP_001732759.1 CDS coaA NC_010473.1 4271796 4272746 R catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase complement(4271796..4272746) Escherichia coli str. K-12 substr. DH10B 6059356 YP_001732760.1 CDS tufB NC_010473.1 4273663 4274847 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 4273663..4274847 Escherichia coli str. K-12 substr. DH10B 6058849 YP_001732761.1 CDS secE NC_010473.1 4275077 4275460 D forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 4275077..4275460 Escherichia coli str. K-12 substr. DH10B 6058921 YP_001732762.1 CDS nusG NC_010473.1 4275462 4276007 D Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 4275462..4276007 Escherichia coli str. K-12 substr. DH10B 6062335 YP_001732763.1 CDS rplK NC_010473.1 4276166 4276594 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 4276166..4276594 Escherichia coli str. K-12 substr. DH10B 6058964 YP_001732764.1 CDS rplA NC_010473.1 4276598 4277302 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 4276598..4277302 Escherichia coli str. K-12 substr. DH10B 6058963 YP_001732765.1 CDS rplJ NC_010473.1 4277715 4278212 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 4277715..4278212 Escherichia coli str. K-12 substr. DH10B 6060388 YP_001732766.1 CDS rplL NC_010473.1 4278279 4278644 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 4278279..4278644 Escherichia coli str. K-12 substr. DH10B 6059866 YP_001732767.1 CDS rpoB NC_010473.1 4278964 4282992 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 4278964..4282992 Escherichia coli str. K-12 substr. DH10B 6058462 YP_001732768.1 CDS rpoC NC_010473.1 4283069 4287292 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 4283069..4287292 Escherichia coli str. K-12 substr. DH10B 6058956 YP_001732769.1 CDS htrC NC_010473.1 4287505 4288044 D heat shock protein 4287505..4288044 Escherichia coli str. K-12 substr. DH10B 6058386 YP_001732770.1 CDS thiH NC_010473.1 4288454 4289587 R in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH complement(4288454..4289587) Escherichia coli str. K-12 substr. DH10B 6058705 YP_001732771.1 CDS thiG NC_010473.1 4289584 4290354 R functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase complement(4289584..4290354) Escherichia coli str. K-12 substr. DH10B 6058862 YP_001732772.1 CDS thiS NC_010473.1 4290356 4290556 R with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS complement(4290356..4290556) Escherichia coli str. K-12 substr. DH10B 6058905 YP_001732773.1 CDS thiF NC_010473.1 4290540 4291295 R thiamin (thiazole moiety) biosynthesis protein complement(4290540..4291295) Escherichia coli str. K-12 substr. DH10B 6059075 YP_001732774.1 CDS thiE NC_010473.1 4291288 4291923 R catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase complement(4291288..4291923) Escherichia coli str. K-12 substr. DH10B 6062414 YP_001732775.1 CDS thiC NC_010473.1 4291923 4293818 R required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC complement(4291923..4293818) Escherichia coli str. K-12 substr. DH10B 6059259 YP_001732776.1 CDS rsd NC_010473.1 4294051 4294527 R binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor complement(4294051..4294527) Escherichia coli str. K-12 substr. DH10B 6059147 YP_001732777.1 CDS nudC NC_010473.1 4294622 4295395 D can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 4294622..4295395 Escherichia coli str. K-12 substr. DH10B 6059900 YP_001732778.1 CDS hemE NC_010473.1 4295435 4296499 D catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 4295435..4296499 Escherichia coli str. K-12 substr. DH10B 6060094 YP_001732779.1 CDS nfi NC_010473.1 4296509 4297180 D Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 4296509..4297180 Escherichia coli str. K-12 substr. DH10B 6058641 YP_001732780.1 CDS yjaG NC_010473.1 4297223 4297813 D hypothetical protein 4297223..4297813 Escherichia coli str. K-12 substr. DH10B 6058873 YP_001732781.1 CDS hupA NC_010473.1 4298000 4298272 D histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 4298000..4298272 Escherichia coli str. K-12 substr. DH10B 6058966 YP_001732782.1 CDS yjaH NC_010473.1 4298285 4298980 D hypothetical protein 4298285..4298980 Escherichia coli str. K-12 substr. DH10B 6058981 YP_001732783.1 CDS zraP NC_010473.1 4298982 4299407 R zinc resistance protein complement(4298982..4299407) Escherichia coli str. K-12 substr. DH10B 6058994 YP_001732784.1 CDS zraS NC_010473.1 4299645 4301042 D sensor protein ZraS 4299645..4301042 Escherichia coli str. K-12 substr. DH10B 6059156 YP_001732785.1 CDS zraR NC_010473.1 4301039 4302364 D DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR 4301039..4302364 Escherichia coli str. K-12 substr. DH10B 6059058 YP_001732786.1 CDS purD NC_010473.1 4302361 4303650 R catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase complement(4302361..4303650) Escherichia coli str. K-12 substr. DH10B 6059195 YP_001732787.1 CDS purH NC_010473.1 4303662 4305251 R involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase complement(4303662..4305251) Escherichia coli str. K-12 substr. DH10B 6059199 YP_001732788.1 CDS yjaA NC_010473.1 4310953 4311336 D hypothetical protein 4310953..4311336 Escherichia coli str. K-12 substr. DH10B 6062188 YP_001732789.1 CDS yjaB NC_010473.1 4311399 4311842 R hypothetical protein complement(4311399..4311842) Escherichia coli str. K-12 substr. DH10B 6059593 YP_001732790.1 CDS metA NC_010473.1 4311999 4312928 D catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 4311999..4312928 Escherichia coli str. K-12 substr. DH10B 6059662 YP_001732791.1 CDS aceB NC_010473.1 4313197 4314798 D Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 4313197..4314798 Escherichia coli str. K-12 substr. DH10B 6059830 YP_001732792.1 CDS aceA NC_010473.1 4314828 4316132 D isocitrate lyase 4314828..4316132 Escherichia coli str. K-12 substr. DH10B 6060308 YP_001732793.1 CDS aceK NC_010473.1 4316315 4318051 D catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase protein 4316315..4318051 Escherichia coli str. K-12 substr. DH10B 6060116 YP_001732794.1 CDS arpA NC_010473.1 4318020 4320206 R regulator of acetyl CoA synthetase complement(4318020..4320206) Escherichia coli str. K-12 substr. DH10B 6059049 YP_001732795.1 CDS iclR NC_010473.1 4320523 4321347 R regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; IclR family transcriptional regulator complement(4320523..4321347) Escherichia coli str. K-12 substr. DH10B 6059026 YP_001732796.1 CDS metH NC_010473.1 4321547 4325230 D one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 4321547..4325230 Escherichia coli str. K-12 substr. DH10B 6059383 YP_001732797.1 CDS yjbB NC_010473.1 4325450 4327081 D transporter 4325450..4327081 Escherichia coli str. K-12 substr. DH10B 6059429 YP_001732798.1 CDS pepE NC_010473.1 4327172 4327861 R alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family; peptidase E complement(4327172..4327861) Escherichia coli str. K-12 substr. DH10B 6059658 YP_001732799.1 CDS rluF NC_010473.1 4328073 4328945 D catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 4328073..4328945 Escherichia coli str. K-12 substr. DH10B 6059766 YP_001732800.1 CDS yjbD NC_010473.1 4329078 4329350 R hypothetical protein complement(4329078..4329350) Escherichia coli str. K-12 substr. DH10B 6060237 YP_001732801.1 CDS lysC NC_010473.1 4329603 4330952 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase III complement(4329603..4330952) Escherichia coli str. K-12 substr. DH10B 6059252 YP_001732802.1 CDS pgi NC_010473.1 4331477 4333126 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 4331477..4333126 Escherichia coli str. K-12 substr. DH10B 6058820 YP_001732803.1 CDS yjbE NC_010473.1 4333625 4333867 D hypothetical protein 4333625..4333867 Escherichia coli str. K-12 substr. DH10B 6060088 YP_001732804.1 CDS yjbF NC_010473.1 4333981 4334619 D lipoprotein 4333981..4334619 Escherichia coli str. K-12 substr. DH10B 6061808 YP_001732805.1 CDS yjbG NC_010473.1 4334616 4335353 D hypothetical protein 4334616..4335353 Escherichia coli str. K-12 substr. DH10B 6061801 YP_001732806.1 CDS yjbH NC_010473.1 4335353 4337449 D porin 4335353..4337449 Escherichia coli str. K-12 substr. DH10B 6061898 YP_001732807.1 CDS yjbA NC_010473.1 4338044 4338454 D phosphate-starvation-inducible protein PsiE 4338044..4338454 Escherichia coli str. K-12 substr. DH10B 6061725 YP_001732808.1 CDS xylE NC_010473.1 4338498 4339973 R xylose/proton symporter; member of the major facilitator superfamily (MFS) of transporter; D-xylose transporter XylE complement(4338498..4339973) Escherichia coli str. K-12 substr. DH10B 6060606 YP_001732809.1 CDS malG NC_010473.1 4340345 4341235 R with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease complement(4340345..4341235) Escherichia coli str. K-12 substr. DH10B 6061810 YP_001732810.1 CDS malF NC_010473.1 4341250 4342794 R with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein complement(4341250..4342794) Escherichia coli str. K-12 substr. DH10B 6061812 YP_001732811.1 CDS malE NC_010473.1 4342948 4344138 R functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein complement(4342948..4344138) Escherichia coli str. K-12 substr. DH10B 6060930 YP_001732812.1 CDS malK NC_010473.1 4344503 4345618 D with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 4344503..4345618 Escherichia coli str. K-12 substr. DH10B 6060983 YP_001732813.1 CDS lamB NC_010473.1 4345690 4347030 D porin involved in the transport of maltose and maltodextrins; maltoporin 4345690..4347030 Escherichia coli str. K-12 substr. DH10B 6060514 YP_001732814.1 CDS malM NC_010473.1 4347273 4348193 D maltose regulon periplasmic protein 4347273..4348193 Escherichia coli str. K-12 substr. DH10B 6062006 YP_001732815.1 CDS yjbI NC_010473.1 4348674 4350002 D in E. coli, some yjbl mutations have been reported as suppressors of dnaG mutations; hypothetical protein 4348674..4350002 Escherichia coli str. K-12 substr. DH10B 6062014 YP_001732816.1 CDS ubiC NC_010473.1 4350225 4350722 D catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 4350225..4350722 Escherichia coli str. K-12 substr. DH10B 6061040 YP_001732817.1 CDS ubiA NC_010473.1 4350735 4351607 D catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 4350735..4351607 Escherichia coli str. K-12 substr. DH10B 6062055 YP_001732818.1 CDS plsB NC_010473.1 4351762 4354185 R PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase complement(4351762..4354185) Escherichia coli str. K-12 substr. DH10B 6062078 YP_001732819.1 CDS dgkA NC_010473.1 4354356 4354724 D diacylglycerol kinase 4354356..4354724 Escherichia coli str. K-12 substr. DH10B 6062060 YP_001732820.1 CDS lexA NC_010473.1 4354834 4355442 D Represses a number of genes involved in the response to DNA damage; LexA repressor 4354834..4355442 Escherichia coli str. K-12 substr. DH10B 6062108 YP_001732821.1 CDS dinF NC_010473.1 4355461 4356840 D DNA-damage-inducible SOS response protein 4355461..4356840 Escherichia coli str. K-12 substr. DH10B 6061117 YP_001732822.1 CDS yjbJ NC_010473.1 4356956 4357165 D unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; putative stress-response protein 4356956..4357165 Escherichia coli str. K-12 substr. DH10B 6061130 YP_001732823.1 CDS zur NC_010473.1 4357207 4357722 R Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor complement(4357207..4357722) Escherichia coli str. K-12 substr. DH10B 6062167 YP_001732824.1 CDS yjbL NC_010473.1 4358040 4358294 D hypothetical protein 4358040..4358294 Escherichia coli str. K-12 substr. DH10B 6060208 YP_001732825.1 CDS yjbM NC_010473.1 4358318 4359025 D hypothetical protein 4358318..4359025 Escherichia coli str. K-12 substr. DH10B 6060628 YP_001732826.1 CDS dusA NC_010473.1 4359388 4360425 D tRNA-dihydrouridine synthase A 4359388..4360425 Escherichia coli str. K-12 substr. DH10B 6060672 YP_001732827.1 CDS pspG NC_010473.1 4360559 4360801 D coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 4360559..4360801 Escherichia coli str. K-12 substr. DH10B 6060706 YP_001732828.1 CDS qor NC_010473.1 4360967 4361950 R quinone oxidoreductase complement(4360967..4361950) Escherichia coli str. K-12 substr. DH10B 6059480 YP_001732829.1 CDS dnaB NC_010473.1 4362033 4363448 D unwinds double stranded DNA; replicative DNA helicase 4362033..4363448 Escherichia coli str. K-12 substr. DH10B 6059699 YP_001732830.1 CDS alr NC_010473.1 4363501 4364580 D converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 4363501..4364580 Escherichia coli str. K-12 substr. DH10B 6062306 YP_001732831.1 CDS tyrB NC_010473.1 4364833 4366026 D catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 4364833..4366026 Escherichia coli str. K-12 substr. DH10B 6062235 YP_001732832.1 CDS aphA NC_010473.1 4367133 4367846 D Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 4367133..4367846 Escherichia coli str. K-12 substr. DH10B 6060468 YP_001732833.1 CDS yjbQ NC_010473.1 4367957 4368373 D hypothetical protein 4367957..4368373 Escherichia coli str. K-12 substr. DH10B 6062295 YP_001732834.1 CDS yjbR NC_010473.1 4368377 4368733 D hypothetical protein 4368377..4368733 Escherichia coli str. K-12 substr. DH10B 6059764 YP_001732835.1 CDS ssb NC_010473.1 4371844 4372380 D binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 4371844..4372380 Escherichia coli str. K-12 substr. DH10B 6059233 YP_001732836.1 CDS yjcB NC_010473.1 4372479 4372760 R inner membrane protein complement(4372479..4372760) Escherichia coli str. K-12 substr. DH10B 6059584 YP_001732837.1 CDS soxS NC_010473.1 4374779 4375102 R regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS complement(4374779..4375102) Escherichia coli str. K-12 substr. DH10B 6059014 YP_001732838.1 CDS soxR NC_010473.1 4375188 4375652 D DNA-binding transcriptional dual regulator, Fe-S center for redox-sensing 4375188..4375652 Escherichia coli str. K-12 substr. DH10B 6059084 YP_001732839.1 CDS yjcD NC_010473.1 4376198 4377547 D permease 4376198..4377547 Escherichia coli str. K-12 substr. DH10B 6059636 YP_001732840.1 CDS yjcE NC_010473.1 4377699 4379348 D cation/proton antiporter 4377699..4379348 Escherichia coli str. K-12 substr. DH10B 6059218 YP_001732841.1 CDS yjcF NC_010473.1 4379502 4380794 R hypothetical protein complement(4379502..4380794) Escherichia coli str. K-12 substr. DH10B 6059367 YP_001732842.1 CDS actP NC_010473.1 4380972 4382621 R member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease complement(4380972..4382621) Escherichia coli str. K-12 substr. DH10B 6059660 YP_001732843.1 CDS yjcH NC_010473.1 4382618 4382932 R inner membrane protein involved in acetate transport complement(4382618..4382932) Escherichia coli str. K-12 substr. DH10B 6058972 YP_001732844.1 CDS acs NC_010473.1 4383132 4385090 R Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase complement(4383132..4385090) Escherichia coli str. K-12 substr. DH10B 6059571 YP_001732845.1 CDS nrfA NC_010473.1 4385483 4386919 D catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552; cytochrome c552 4385483..4386919 Escherichia coli str. K-12 substr. DH10B 6060249 YP_001732846.1 CDS nrfC NC_010473.1 4388304 4388975 D formate-dependent nitrite reductase, 4Fe4S subunit 4388304..4388975 Escherichia coli str. K-12 substr. DH10B 6061618 YP_001732847.1 CDS nrfD NC_010473.1 4388972 4389928 D formate-dependent nitrite reductase, membrane subunit 4388972..4389928 Escherichia coli str. K-12 substr. DH10B 6061467 YP_001732848.1 CDS nrfE NC_010473.1 4390008 4391666 D with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552; heme lyase subunit NrfE 4390008..4391666 Escherichia coli str. K-12 substr. DH10B 6061371 YP_001732849.1 CDS nrfF NC_010473.1 4391659 4392042 D formate-dependent nitrite reductase complex subunit NrfF 4391659..4392042 Escherichia coli str. K-12 substr. DH10B 6062431 YP_001732850.1 CDS nrfG NC_010473.1 4392039 4392635 D formate-dependent nitrite reductase complex subunit NrfG 4392039..4392635 Escherichia coli str. K-12 substr. DH10B 6061264 YP_001732851.1 CDS gltP NC_010473.1 4392977 4394290 D carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 4392977..4394290 Escherichia coli str. K-12 substr. DH10B 6061168 YP_001732852.1 CDS yjcO NC_010473.1 4394821 4395510 R hypothetical protein complement(4394821..4395510) Escherichia coli str. K-12 substr. DH10B 6060958 YP_001732853.1 CDS fdhF NC_010473.1 4395604 4397751 R formate dehydrogenase-H, selenopolypeptide subunit complement(4395604..4397751) Escherichia coli str. K-12 substr. DH10B 6058767 YP_001732854.1 CDS yjcP NC_010473.1 4397949 4399415 R part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; putative outer membrane efflux protein MdtP complement(4397949..4399415) Escherichia coli str. K-12 substr. DH10B 6060979 YP_001732855.1 CDS yjcQ NC_010473.1 4399412 4401463 R possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO complement(4399412..4401463) Escherichia coli str. K-12 substr. DH10B 6060892 YP_001732856.1 CDS yjcR NC_010473.1 4401463 4402494 R with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN complement(4401463..4402494) Escherichia coli str. K-12 substr. DH10B 6060791 YP_001732857.1 CDS yjcS NC_010473.1 4402997 4404982 R alkyl sulfatase complement(4402997..4404982) Escherichia coli str. K-12 substr. DH10B 6060748 YP_001732858.1 CDS alsK NC_010473.1 4405255 4406184 R D-allose kinase complement(4405255..4406184) Escherichia coli str. K-12 substr. DH10B 6059889 YP_001732859.1 CDS alsE NC_010473.1 4406168 4406863 R allulose-6-phosphate 3-epimerase complement(4406168..4406863) Escherichia coli str. K-12 substr. DH10B 6060001 YP_001732860.1 CDS alsC NC_010473.1 4406874 4407854 R D-allose transporter subunit complement(4406874..4407854) Escherichia coli str. K-12 substr. DH10B 6060392 YP_001732861.1 CDS alsA NC_010473.1 4407833 4409365 R with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains; D-allose transporter ATP-binding protein complement(4407833..4409365) Escherichia coli str. K-12 substr. DH10B 6062206 YP_001732862.1 CDS alsB NC_010473.1 4409492 4410427 R D-allose transporter subunit complement(4409492..4410427) Escherichia coli str. K-12 substr. DH10B 6059111 YP_001732863.1 CDS rpiR NC_010473.1 4410486 4411376 R involved in rpiB and als operon repression; DNA-binding transcriptional repressor RpiR complement(4410486..4411376) Escherichia coli str. K-12 substr. DH10B 6059487 YP_001732864.1 CDS rpiB NC_010473.1 4411735 4412184 D catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 4411735..4412184 Escherichia coli str. K-12 substr. DH10B 6059494 YP_001732865.1 CDS yjdP NC_010473.1 4412253 4412582 D hypothetical protein 4412253..4412582 Escherichia coli str. K-12 substr. DH10B 6059547 YP_001732866.1 CDS phnP NC_010473.1 4412729 4413487 R required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein complement(4412729..4413487) Escherichia coli str. K-12 substr. DH10B 6059574 YP_001732867.1 CDS phnO NC_010473.1 4413489 4413923 R PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role; aminoalkylphosphonic acid N-acetyltransferase complement(4413489..4413923) Escherichia coli str. K-12 substr. DH10B 6059625 YP_001732868.1 CDS phnN NC_010473.1 4413910 4414467 R ribose 1,5-bisphosphokinase complement(4413910..4414467) Escherichia coli str. K-12 substr. DH10B 6059741 YP_001732869.1 CDS phnM NC_010473.1 4414467 4415603 R carbon-phosphorus lyase complex subunit complement(4414467..4415603) Escherichia coli str. K-12 substr. DH10B 6059748 YP_001732870.1 CDS phnL NC_010473.1 4415600 4416280 R carbon-phosphorus lyase complex subunit complement(4415600..4416280) Escherichia coli str. K-12 substr. DH10B 6059729 YP_001732871.1 CDS phnK NC_010473.1 4416391 4417149 R phosphonate C-P lyase system protein PhnK complement(4416391..4417149) Escherichia coli str. K-12 substr. DH10B 6059761 YP_001732872.1 CDS phnJ NC_010473.1 4417146 4417991 R carbon-phosphorus lyase complex subunit complement(4417146..4417991) Escherichia coli str. K-12 substr. DH10B 6059906 YP_001732873.1 CDS phnI NC_010473.1 4417984 4419048 R carbon-phosphorus lyase complex subunit complement(4417984..4419048) Escherichia coli str. K-12 substr. DH10B 6059965 YP_001732874.1 CDS phnH NC_010473.1 4419048 4419632 R carbon-phosphorus lyase complex subunit complement(4419048..4419632) Escherichia coli str. K-12 substr. DH10B 6059834 YP_001732875.1 CDS phnG NC_010473.1 4419629 4420081 R carbon-phosphorus lyase complex subunit complement(4419629..4420081) Escherichia coli str. K-12 substr. DH10B 6059892 YP_001732876.1 CDS phnF NC_010473.1 4420082 4420807 R may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF complement(4420082..4420807) Escherichia coli str. K-12 substr. DH10B 6060302 YP_001732877.1 CDS phnD NC_010473.1 4421721 4422737 R phosphonate/organophosphate ester ABC transporter periplasmic-binding protein complement(4421721..4422737) Escherichia coli str. K-12 substr. DH10B 6060449 YP_001732878.1 CDS phnC NC_010473.1 4422762 4423550 R phosphonate/organophosphate ester transporter subunit complement(4422762..4423550) Escherichia coli str. K-12 substr. DH10B 6058189 YP_001732879.1 CDS phnB NC_010473.1 4423683 4424126 R hypothetical protein complement(4423683..4424126) Escherichia coli str. K-12 substr. DH10B 6058654 YP_001732880.1 CDS phnA NC_010473.1 4424784 4425119 R hypothetical protein complement(4424784..4425119) Escherichia coli str. K-12 substr. DH10B 6058665 YP_001732881.1 CDS yjdA NC_010473.1 4425520 4427748 D hypothetical protein 4425520..4427748 Escherichia coli str. K-12 substr. DH10B 6062392 YP_001732882.1 CDS yjcZ NC_010473.1 4427745 4428623 D hypothetical protein 4427745..4428623 Escherichia coli str. K-12 substr. DH10B 6062291 YP_001732883.1 CDS proP NC_010473.1 4428887 4430389 D proline/glycine betaine transporter 4428887..4430389 Escherichia coli str. K-12 substr. DH10B 6062147 YP_001732884.1 CDS basS NC_010473.1 4430566 4431657 R sensor protein BasS/PmrB complement(4430566..4431657) Escherichia coli str. K-12 substr. DH10B 6062157 YP_001732885.1 CDS basR NC_010473.1 4431667 4432335 R response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR complement(4431667..4432335) Escherichia coli str. K-12 substr. DH10B 6062068 YP_001732886.1 CDS eptA NC_010473.1 4432332 4433975 R with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; putative cell division protein complement(4432332..4433975) Escherichia coli str. K-12 substr. DH10B 6061998 YP_001732887.1 CDS adiC NC_010473.1 4434079 4435416 R arginine:agmatin antiporter complement(4434079..4435416) Escherichia coli str. K-12 substr. DH10B 6062040 YP_001732888.1 CDS melR NC_010473.1 4439105 4440013 R DNA-binding transcriptional regulator MelR complement(4439105..4440013) Escherichia coli str. K-12 substr. DH10B 6062023 YP_001732889.1 CDS melA NC_010473.1 4440296 4441651 D alpha-galactosidase, NAD(P)-binding 4440296..4441651 Escherichia coli str. K-12 substr. DH10B 6061993 YP_001732890.1 CDS melB NC_010473.1 4441766 4443175 D melibiose:sodium symporter 4441766..4443175 Escherichia coli str. K-12 substr. DH10B 6061981 YP_001732891.1 CDS yjdF NC_010473.1 4443314 4443943 R hypothetical protein complement(4443314..4443943) Escherichia coli str. K-12 substr. DH10B 6061979 YP_001732892.1 CDS fumB NC_010473.1 4444065 4445711 R anaerobic class I fumarate hydratase complement(4444065..4445711) Escherichia coli str. K-12 substr. DH10B 6061932 YP_001732893.1 CDS dcuB NC_010473.1 4445789 4447129 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter complement(4445789..4447129) Escherichia coli str. K-12 substr. DH10B 6061959 YP_001732894.1 CDS dcuS NC_010473.1 4448416 4450047 R C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS complement(4448416..4450047) Escherichia coli str. K-12 substr. DH10B 6061948 YP_001732895.1 CDS yjdI NC_010473.1 4450228 4450458 D hypothetical protein 4450228..4450458 Escherichia coli str. K-12 substr. DH10B 6061943 YP_001732896.1 CDS yjdJ NC_010473.1 4450470 4450742 D acyltransferase 4450470..4450742 Escherichia coli str. K-12 substr. DH10B 6061944 YP_001732897.1 CDS yjdK NC_010473.1 4450969 4451265 D hypothetical protein 4450969..4451265 Escherichia coli str. K-12 substr. DH10B 6061935 YP_001732898.1 CDS yjdO NC_010473.1 4451293 4451466 D hypothetical protein 4451293..4451466 Escherichia coli str. K-12 substr. DH10B 6061938 YP_001732899.1 CDS lysU NC_010473.1 4451585 4453102 R class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(4451585..4453102) Escherichia coli str. K-12 substr. DH10B 6061871 YP_001732900.1 CDS yjdL NC_010473.1 4453339 4454796 R transporter complement(4453339..4454796) Escherichia coli str. K-12 substr. DH10B 6061891 YP_001732901.1 CDS cadA NC_010473.1 4454855 4457002 R lysine decarboxylase 1 complement(4454855..4457002) Escherichia coli str. K-12 substr. DH10B 6061887 YP_001732902.1 CDS cadB NC_010473.1 4457082 4458416 R antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter complement(4457082..4458416) Escherichia coli str. K-12 substr. DH10B 6061764 YP_001732903.1 CDS cadC NC_010473.1 4458781 4460319 R regulates the cadBA operon; DNA-binding transcriptional activator CadC complement(4458781..4460319) Escherichia coli str. K-12 substr. DH10B 6061742 YP_001732904.1 CDS yjdC NC_010473.1 4461118 4461693 R putative transcriptional regulator complement(4461118..4461693) Escherichia coli str. K-12 substr. DH10B 6059677 YP_001732905.1 CDS dipZ NC_010473.1 4461730 4463427 R two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein complement(4461730..4463427) Escherichia coli str. K-12 substr. DH10B 6061698 YP_001732906.1 CDS cutA NC_010473.1 4463403 4463741 R copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA complement(4463403..4463741) Escherichia coli str. K-12 substr. DH10B 6061659 YP_001732907.1 CDS dcuA NC_010473.1 4463857 4465158 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter complement(4463857..4465158) Escherichia coli str. K-12 substr. DH10B 6061642 YP_001732908.1 CDS aspA NC_010473.1 4465276 4466712 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(4465276..4466712) Escherichia coli str. K-12 substr. DH10B 6061587 YP_001732909.1 CDS fxsA NC_010473.1 4467049 4467525 D F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 4467049..4467525 Escherichia coli str. K-12 substr. DH10B 6061492 YP_001732910.1 CDS yjeH NC_010473.1 4467541 4468797 R uncharacterized member of the APC superfamily of amino acid transporters; unknown function; inner membrane protein YjeH complement(4467541..4468797) Escherichia coli str. K-12 substr. DH10B 6061385 YP_001732911.1 CDS groES NC_010473.1 4469073 4469366 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 4469073..4469366 Escherichia coli str. K-12 substr. DH10B 6061370 YP_001732912.1 CDS groEL NC_010473.1 4469410 4471056 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 4469410..4471056 Escherichia coli str. K-12 substr. DH10B 6061450 YP_001732913.1 CDS yjeI NC_010473.1 4471194 4471547 D hypothetical protein 4471194..4471547 Escherichia coli str. K-12 substr. DH10B 6061415 YP_001732914.1 CDS yjeJ NC_010473.1 4471750 4472619 R hypothetical protein complement(4471750..4472619) Escherichia coli str. K-12 substr. DH10B 6061428 YP_001732915.1 CDS efp NC_010473.1 4474084 4474650 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 4474084..4474650 Escherichia coli str. K-12 substr. DH10B 6061410 YP_001732916.1 CDS ecnA NC_010473.1 4474702 4474827 D acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex; entericidin A 4474702..4474827 Escherichia coli str. K-12 substr. DH10B 6061249 YP_001732917.1 CDS ecnB NC_010473.1 4474938 4475084 D entericidin B membrane lipoprotein 4474938..4475084 Escherichia coli str. K-12 substr. DH10B 6061240 YP_001732918.1 CDS sugE NC_010473.1 4475260 4475577 D member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; quaternary ammonium compound-resistance protein SugE 4475260..4475577 Escherichia coli str. K-12 substr. DH10B 6061330 YP_001732919.1 CDS blc NC_010473.1 4475574 4476107 R lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc complement(4475574..4476107) Escherichia coli str. K-12 substr. DH10B 6061284 YP_001732920.1 CDS ampC NC_010473.1 4476196 4477329 R beta-lactamase complement(4476196..4477329) Escherichia coli str. K-12 substr. DH10B 6061224 YP_001732921.1 CDS frdD NC_010473.1 4477392 4477751 R in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D complement(4477392..4477751) Escherichia coli str. K-12 substr. DH10B 6061190 YP_001732922.1 CDS frdC NC_010473.1 4477762 4478157 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C complement(4477762..4478157) Escherichia coli str. K-12 substr. DH10B 6061148 YP_001732923.1 CDS frdA NC_010473.1 4478895 4480703 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(4478895..4480703) Escherichia coli str. K-12 substr. DH10B 6061106 YP_001732924.1 CDS poxA NC_010473.1 4481028 4482005 D lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 4481028..4482005 Escherichia coli str. K-12 substr. DH10B 6061093 YP_001732925.1 CDS yjeM NC_010473.1 4482224 4483726 D transporter 4482224..4483726 Escherichia coli str. K-12 substr. DH10B 6061086 YP_001732926.1 CDS yjeN NC_010473.1 4483778 4484092 D hypothetical protein 4483778..4484092 Escherichia coli str. K-12 substr. DH10B 6061083 YP_001732927.1 CDS yjeO NC_010473.1 4484089 4484403 D inner membrane protein 4484089..4484403 Escherichia coli str. K-12 substr. DH10B 6061050 YP_001732928.1 CDS yjeP NC_010473.1 4484432 4487755 R hypothetical protein complement(4484432..4487755) Escherichia coli str. K-12 substr. DH10B 6060997 YP_001732929.1 CDS psd NC_010473.1 4487777 4488745 R catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase complement(4487777..4488745) Escherichia coli str. K-12 substr. DH10B 6060679 YP_001732930.1 CDS rsgA NC_010473.1 4488842 4489894 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(4488842..4489894) Escherichia coli str. K-12 substr. DH10B 6060835 YP_001732931.1 CDS orn NC_010473.1 4489989 4490534 D 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 4489989..4490534 Escherichia coli str. K-12 substr. DH10B 6060787 YP_001732932.1 CDS yjeS NC_010473.1 4491313 4492452 R Fe-S electron transport protein complement(4491313..4492452) Escherichia coli str. K-12 substr. DH10B 6059773 YP_001732933.1 CDS yjeF NC_010473.1 4492451 4493998 D hypothetical protein 4492451..4493998 Escherichia coli str. K-12 substr. DH10B 6062342 YP_001732934.1 CDS yjeE NC_010473.1 4493970 4494431 D possibly involved in cell wall synthesis; putative ATPase 4493970..4494431 Escherichia coli str. K-12 substr. DH10B 6062372 YP_001732935.1 CDS amiB NC_010473.1 4494450 4495787 D N-acetylmuramoyl-l-alanine amidase II 4494450..4495787 Escherichia coli str. K-12 substr. DH10B 6062112 YP_001732936.1 CDS mutL NC_010473.1 4495797 4497644 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 4495797..4497644 Escherichia coli str. K-12 substr. DH10B 6062265 YP_001732937.1 CDS miaA NC_010473.1 4497637 4498587 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 4497637..4498587 Escherichia coli str. K-12 substr. DH10B 6058647 YP_001732938.1 CDS hfq NC_010473.1 4498673 4498981 D Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 4498673..4498981 Escherichia coli str. K-12 substr. DH10B 6059274 YP_001732939.1 CDS hflX NC_010473.1 4499057 4500337 D involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; putative GTPase HflX 4499057..4500337 Escherichia coli str. K-12 substr. DH10B 6062200 YP_001732940.1 CDS hflK NC_010473.1 4500423 4501682 D with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 4500423..4501682 Escherichia coli str. K-12 substr. DH10B 6060766 YP_001732941.1 CDS hflC NC_010473.1 4501685 4502689 D with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 4501685..4502689 Escherichia coli str. K-12 substr. DH10B 6058965 YP_001732942.1 CDS yjeT NC_010473.1 4502771 4502968 D inner membrane protein 4502771..4502968 Escherichia coli str. K-12 substr. DH10B 6058882 YP_001732943.1 CDS purA NC_010473.1 4503072 4504370 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 4503072..4504370 Escherichia coli str. K-12 substr. DH10B 6058928 YP_001732944.1 CDS nsrR NC_010473.1 4504575 4505000 D negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 4504575..4505000 Escherichia coli str. K-12 substr. DH10B 6060699 YP_001732945.1 CDS rnr NC_010473.1 4505039 4507480 D 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 4505039..4507480 Escherichia coli str. K-12 substr. DH10B 6060537 YP_001732946.1 CDS rlmB NC_010473.1 4507660 4508391 D Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 4507660..4508391 Escherichia coli str. K-12 substr. DH10B 6060608 YP_001732947.1 CDS yjfI NC_010473.1 4508518 4508919 D hypothetical protein 4508518..4508919 Escherichia coli str. K-12 substr. DH10B 6060183 YP_001732948.1 CDS yjfJ NC_010473.1 4508938 4509636 D transcriptional regulator effector protein 4508938..4509636 Escherichia coli str. K-12 substr. DH10B 6062096 YP_001732949.1 CDS yjfK NC_010473.1 4509687 4510346 D hypothetical protein 4509687..4510346 Escherichia coli str. K-12 substr. DH10B 6062141 YP_001732950.1 CDS yjfL NC_010473.1 4510364 4510762 D inner membrane protein 4510364..4510762 Escherichia coli str. K-12 substr. DH10B 6060654 YP_001732951.1 CDS yjfM NC_010473.1 4510772 4511410 D hypothetical protein 4510772..4511410 Escherichia coli str. K-12 substr. DH10B 6060990 YP_001732952.1 CDS yjfC NC_010473.1 4511413 4512576 D synthetase/amidase 4511413..4512576 Escherichia coli str. K-12 substr. DH10B 6060558 YP_001732953.1 CDS aidB NC_010473.1 4512660 4514285 D catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 4512660..4514285 Escherichia coli str. K-12 substr. DH10B 6062061 YP_001732954.1 CDS yjfN NC_010473.1 4514402 4514677 R hypothetical protein complement(4514402..4514677) Escherichia coli str. K-12 substr. DH10B 6062021 YP_001732955.1 CDS yjfO NC_010473.1 4514826 4515155 R in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; putative biofilm stress and motility protein A complement(4514826..4515155) Escherichia coli str. K-12 substr. DH10B 6061976 YP_001732956.1 CDS yjfP NC_010473.1 4515337 4516086 D YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 4515337..4516086 Escherichia coli str. K-12 substr. DH10B 6061014 YP_001732957.1 CDS ulaR NC_010473.1 4516083 4516838 R negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR complement(4516083..4516838) Escherichia coli str. K-12 substr. DH10B 6061962 YP_001732958.1 CDS ulaG NC_010473.1 4516946 4518010 R putative L-ascorbate 6-phosphate lactonase complement(4516946..4518010) Escherichia coli str. K-12 substr. DH10B 6061937 YP_001732959.1 CDS ulaA NC_010473.1 4518365 4519762 D membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 4518365..4519762 Escherichia coli str. K-12 substr. DH10B 6060975 YP_001732960.1 CDS ulaB NC_010473.1 4519778 4520083 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIB 4519778..4520083 Escherichia coli str. K-12 substr. DH10B 6059686 YP_001732961.1 CDS ulaC NC_010473.1 4520093 4520557 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIA 4520093..4520557 Escherichia coli str. K-12 substr. DH10B 6061895 YP_001732962.1 CDS ulaD NC_010473.1 4520571 4521221 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 4520571..4521221 Escherichia coli str. K-12 substr. DH10B 6061918 YP_001732963.1 CDS ulaE NC_010473.1 4521231 4522085 D UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 4521231..4522085 Escherichia coli str. K-12 substr. DH10B 6061777 YP_001732964.1 CDS sgaE NC_010473.1 4522085 4522771 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4522085..4522771 Escherichia coli str. K-12 substr. DH10B 6060928 YP_001732965.1 CDS yjfY NC_010473.1 4522901 4523176 R hypothetical protein complement(4522901..4523176) Escherichia coli str. K-12 substr. DH10B 6060926 YP_001732966.1 CDS rpsF NC_010473.1 4523503 4523898 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 4523503..4523898 Escherichia coli str. K-12 substr. DH10B 6061865 YP_001732967.1 CDS rpsR NC_010473.1 4524224 4524451 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 4524224..4524451 Escherichia coli str. K-12 substr. DH10B 6061803 YP_001732968.1 CDS rplI NC_010473.1 4524493 4524942 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 4524493..4524942 Escherichia coli str. K-12 substr. DH10B 6061787 YP_001732969.1 CDS yjfZ NC_010473.1 4525013 4525807 R hypothetical protein complement(4525013..4525807) Escherichia coli str. K-12 substr. DH10B 6060589 YP_001732970.1 CDS ytfA NC_010473.1 4526154 4526480 D transcriptional regulator 4526154..4526480 Escherichia coli str. K-12 substr. DH10B 6061723 YP_001732971.1 CDS ytfB NC_010473.1 4526464 4527102 R cell envelope opacity-associated protein complement(4526464..4527102) Escherichia coli str. K-12 substr. DH10B 6061705 YP_001732972.1 CDS fklB NC_010473.1 4527320 4527940 D FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 4527320..4527940 Escherichia coli str. K-12 substr. DH10B 6061716 YP_001732973.1 CDS cycA NC_010473.1 4528249 4529661 D involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 4528249..4529661 Escherichia coli str. K-12 substr. DH10B 6059485 YP_001732974.1 CDS ytfE NC_010473.1 4529706 4530368 R Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein complement(4529706..4530368) Escherichia coli str. K-12 substr. DH10B 6060842 YP_001732975.1 CDS ytfF NC_010473.1 4530476 4531450 R inner membrane protein complement(4530476..4531450) Escherichia coli str. K-12 substr. DH10B 6061658 YP_001732976.1 CDS ytfG NC_010473.1 4531549 4532409 R NAD(P)H:quinone oxidoreductase complement(4531549..4532409) Escherichia coli str. K-12 substr. DH10B 6061688 YP_001732977.1 CDS ytfH NC_010473.1 4532498 4532878 D transcriptional regulator 4532498..4532878 Escherichia coli str. K-12 substr. DH10B 6058626 YP_001732978.1 CDS cpdB NC_010473.1 4533007 4534950 R periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein complement(4533007..4534950) Escherichia coli str. K-12 substr. DH10B 6061645 YP_001732979.1 CDS ytfI NC_010473.1 4536092 4537030 D hypothetical protein 4536092..4537030 Escherichia coli str. K-12 substr. DH10B 6060817 YP_001732980.1 CDS ytfJ NC_010473.1 4537093 4537647 R transcriptional regulator complement(4537093..4537647) Escherichia coli str. K-12 substr. DH10B 6061559 YP_001732981.1 CDS ytfK NC_010473.1 4537972 4538178 D hypothetical protein 4537972..4538178 Escherichia coli str. K-12 substr. DH10B 6060670 YP_001732982.1 CDS ytfL NC_010473.1 4538257 4539600 R inner membrane protein complement(4538257..4539600) Escherichia coli str. K-12 substr. DH10B 6061543 YP_001732983.1 CDS msrA NC_010473.1 4539923 4540561 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A complement(4539923..4540561) Escherichia coli str. K-12 substr. DH10B 6061530 YP_001732984.1 CDS ytfM NC_010473.1 4540767 4542500 D outer membrane protein 4540767..4542500 Escherichia coli str. K-12 substr. DH10B 6061419 YP_001732985.1 CDS ytfN NC_010473.1 4542497 4546276 D hypothetical protein 4542497..4546276 Escherichia coli str. K-12 substr. DH10B 6061447 YP_001732986.1 CDS ytfP NC_010473.1 4546279 4546620 D hypothetical protein 4546279..4546620 Escherichia coli str. K-12 substr. DH10B 6061421 YP_001732987.1 CDS yzfA NC_010473.1 4546361 4546630 R hypothetical protein complement(4546361..4546630) Escherichia coli str. K-12 substr. DH10B 6061416 YP_001732988.1 CDS chpS NC_010473.1 4546832 4547083 D part of the toxin-antitoxin ChpB-ChpS system; antitoxin ChpS 4546832..4547083 Escherichia coli str. K-12 substr. DH10B 6061430 YP_001732989.1 CDS chpB NC_010473.1 4547077 4547427 D toxin of the ChpB-ChpS toxin-antitoxin system; toxin ChpB 4547077..4547427 Escherichia coli str. K-12 substr. DH10B 6061387 YP_001732990.1 CDS ppa NC_010473.1 4547507 4548037 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(4547507..4548037) Escherichia coli str. K-12 substr. DH10B 6060756 YP_001732991.1 CDS ytfQ NC_010473.1 4548347 4549303 D sugar ABC transporter periplasmic-binding protein 4548347..4549303 Escherichia coli str. K-12 substr. DH10B 6061357 YP_001732992.1 CDS ytfR NC_010473.1 4549443 4550945 D sugar ABC transporter ATP-binding protein 4549443..4550945 Escherichia coli str. K-12 substr. DH10B 6061360 YP_001732993.1 CDS yjfF NC_010473.1 4553414 4554409 D membrane component of a putative sugar ABC transporter system; inner membrane ABC transporter permease YjfF 4553414..4554409 Escherichia coli str. K-12 substr. DH10B 6061785 YP_001732994.1 CDS fbp NC_010473.1 4554442 4555440 R catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase complement(4554442..4555440) Escherichia coli str. K-12 substr. DH10B 6061350 YP_001732995.1 CDS mpl NC_010473.1 4555616 4556989 D UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 4555616..4556989 Escherichia coli str. K-12 substr. DH10B 6061338 YP_001732996.1 CDS yjgA NC_010473.1 4557145 4557696 R hypothetical protein complement(4557145..4557696) Escherichia coli str. K-12 substr. DH10B 6060720 YP_001732997.1 CDS pmbA NC_010473.1 4557790 4559142 D protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 4557790..4559142 Escherichia coli str. K-12 substr. DH10B 6061245 YP_001732998.1 CDS nrdG NC_010473.1 4559731 4560195 R activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein complement(4559731..4560195) Escherichia coli str. K-12 substr. DH10B 6059177 YP_001732999.1 CDS nrdD NC_010473.1 4560353 4562491 R Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase complement(4560353..4562491) Escherichia coli str. K-12 substr. DH10B 6061201 YP_001733000.1 CDS treC NC_010473.1 4562885 4564540 R trehalose-6-phosphate hydrolase complement(4562885..4564540) Escherichia coli str. K-12 substr. DH10B 6061110 YP_001733001.1 CDS treB NC_010473.1 4564590 4566011 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunit IIBC complement(4564590..4566011) Escherichia coli str. K-12 substr. DH10B 6060993 YP_001733002.1 CDS treR NC_010473.1 4566130 4567077 R regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor complement(4566130..4567077) Escherichia coli str. K-12 substr. DH10B 6061194 YP_001733003.1 CDS mgtA NC_010473.1 4567456 4570152 D P-type ATPase involved in magnesium influx; magnesium-transporting ATPase MgtA 4567456..4570152 Escherichia coli str. K-12 substr. DH10B 6061172 YP_001733004.1 CDS yjgF NC_010473.1 4570358 4570744 R ketoacid-binding protein complement(4570358..4570744) Escherichia coli str. K-12 substr. DH10B 6059102 YP_001733005.1 CDS pyrI NC_010473.1 4570817 4571278 R involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase regulatory subunit complement(4570817..4571278) Escherichia coli str. K-12 substr. DH10B 6061923 YP_001733006.1 CDS pyrB NC_010473.1 4571291 4572226 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit complement(4571291..4572226) Escherichia coli str. K-12 substr. DH10B 6061951 YP_001733007.1 CDS pyrL NC_010473.1 4572230 4572364 R pyrBI operon leader peptide complement(4572230..4572364) Escherichia coli str. K-12 substr. DH10B 6062137 YP_001733008.1 CDS yjgH NC_010473.1 4572645 4573040 R mRNA endoribonuclease complement(4572645..4573040) Escherichia coli str. K-12 substr. DH10B 6062251 YP_001733009.1 CDS yjgI NC_010473.1 4573171 4573884 R oxidoreductase complement(4573171..4573884) Escherichia coli str. K-12 substr. DH10B 6062263 YP_001733010.1 CDS yjgJ NC_010473.1 4573955 4574548 D transcriptional regulator 4573955..4574548 Escherichia coli str. K-12 substr. DH10B 6059348 YP_001733011.1 CDS yjgK NC_010473.1 4574693 4575145 D hypothetical protein 4574693..4575145 Escherichia coli str. K-12 substr. DH10B 6059877 YP_001733012.1 CDS yjgL NC_010473.1 4575268 4577082 D hypothetical protein 4575268..4577082 Escherichia coli str. K-12 substr. DH10B 6060081 YP_001733013.1 CDS argI NC_010473.1 4577138 4578142 R catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.; ornithine carbamoyltransferase subunit I complement(4577138..4578142) Escherichia coli str. K-12 substr. DH10B 6060776 YP_001733014.1 CDS rraB NC_010473.1 4578304 4578720 D hypothetical protein 4578304..4578720 Escherichia coli str. K-12 substr. DH10B 6058694 YP_001733015.1 CDS yjgM NC_010473.1 4578865 4579368 R acetyltransferase complement(4578865..4579368) Escherichia coli str. K-12 substr. DH10B 6058692 YP_001733016.1 CDS yjgN NC_010473.1 4579561 4580757 D inner membrane protein 4579561..4580757 Escherichia coli str. K-12 substr. DH10B 6058744 YP_001733017.1 CDS valS NC_010473.1 4580813 4583668 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(4580813..4583668) Escherichia coli str. K-12 substr. DH10B 6060190 YP_001733018.1 CDS holC NC_010473.1 4583668 4584111 R binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi complement(4583668..4584111) Escherichia coli str. K-12 substr. DH10B 6060883 YP_001733019.1 CDS pepA NC_010473.1 4584271 4585782 R catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase complement(4584271..4585782) Escherichia coli str. K-12 substr. DH10B 6058826 YP_001733020.1 CDS yjgP NC_010473.1 4586049 4587149 D inner membrane protein 4586049..4587149 Escherichia coli str. K-12 substr. DH10B 6058898 YP_001733021.1 CDS yjgQ NC_010473.1 4587149 4588231 D inner membrane protein 4587149..4588231 Escherichia coli str. K-12 substr. DH10B 6058902 YP_001733022.1 CDS yjgR NC_010473.1 4588392 4589894 R ATPase complement(4588392..4589894) Escherichia coli str. K-12 substr. DH10B 6058901 YP_001733023.1 CDS idnR NC_010473.1 4589972 4590970 R DNA-binding transcriptional repressor, 5-gluconate-binding complement(4589972..4590970) Escherichia coli str. K-12 substr. DH10B 6058933 YP_001733024.1 CDS idnT NC_010473.1 4591037 4592356 R L-idonate and D-gluconate transporter complement(4591037..4592356) Escherichia coli str. K-12 substr. DH10B 6058935 YP_001733025.1 CDS idnO NC_010473.1 4592418 4593182 R Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase complement(4592418..4593182) Escherichia coli str. K-12 substr. DH10B 6058976 YP_001733026.1 CDS idnD NC_010473.1 4593206 4594237 R NAD-binding; L-idonate 5-dehydrogenase complement(4593206..4594237) Escherichia coli str. K-12 substr. DH10B 6058999 YP_001733027.1 CDS idnK NC_010473.1 4594454 4595017 D D-gluconate kinase 4594454..4595017 Escherichia coli str. K-12 substr. DH10B 6060389 YP_001733028.1 CDS yjgB NC_010473.1 4595021 4596040 R Zn-dependent/NAD(P)-binding alcohol dehydrogenase complement(4595021..4596040) Escherichia coli str. K-12 substr. DH10B 6058993 YP_001733029.1 CDS intB NC_010473.1 4596581 4597771 D KpLE2 phage-like element; integrase 4596581..4597771 Escherichia coli str. K-12 substr. DH10B 6059987 YP_001733030.1 CDS insC-6 NC_010473.1 4598058 4598468 D IS2 OrfA; forms an overlapping reading frame with orfB; may form a fusion protein OrfAB due to ribosomal frameshifting; both OrfA and OrfAB bind terminal inverted repeats; insertion sequence 2 OrfA protein 4598058..4598468 Escherichia coli str. K-12 substr. DH10B 6059063 YP_001733031.1 CDS insD-6 NC_010473.1 4598426 4599331 D IS2 OrfB; forms an overlapping reading frame with orfA; may form a fusion protein OrfAB due to ribosomal frameshifting; in some cases OrfB is itself expressed; both OrfA and OrfAB bind terminal inverted repeats; insertion element IS2 transposase InsD 4598426..4599331 Escherichia coli str. K-12 substr. DH10B 6058996 YP_001733032.1 CDS yjgW NC_010473.1 4599430 4599765 D KpLE2 phage-like element; protein 4599430..4599765 Escherichia coli str. K-12 substr. DH10B 6059067 YP_001733033.1 CDS yjgZ NC_010473.1 4601091 4601420 D KpLE2 phage-like element; protein 4601091..4601420 Escherichia coli str. K-12 substr. DH10B 6059085 YP_001733034.1 CDS insG NC_010473.1 4601934 4603262 R KpLE2 phage-like element; IS4 transposase complement(4601934..4603262) Escherichia coli str. K-12 substr. DH10B 6059096 YP_001733035.1 CDS yjhB NC_010473.1 4603889 4605106 D putative sialic acid transporter 4603889..4605106 Escherichia coli str. K-12 substr. DH10B 6059107 YP_001733036.1 CDS yjhC NC_010473.1 4605118 4606236 D KpLE2 phage-like element; oxidoreductase 4605118..4606236 Escherichia coli str. K-12 substr. DH10B 6059103 YP_001733037.1 CDS insN-2 NC_010473.1 4607028 4607294 D KpLE2 phage-like element; partial regulator of insertion element IS911B 4607028..4607294 Escherichia coli str. K-12 substr. DH10B 6059539 YP_001733038.1 CDS insI-3 NC_010473.1 4607297 4608448 R KpLE2 phage-like element; IS30 transposase complement(4607297..4608448) Escherichia coli str. K-12 substr. DH10B 6059185 YP_001733039.1 CDS insO-2 NC_010473.1 4608789 4609385 D KpLE2 phage-like element; partial transposase of insertion element IS911B 4608789..4609385 Escherichia coli str. K-12 substr. DH10B 6059133 YP_001733040.1 CDS yjhV NC_010473.1 4609551 4609964 D KpLE2 phage-like element; protein 4609551..4609964 Escherichia coli str. K-12 substr. DH10B 6061720 YP_001733041.1 CDS fecE NC_010473.1 4610521 4611288 R Part of the FecBCDE citrate-dependent iron (III) transport system; iron-dicitrate transporter ATP-binding subunit complement(4610521..4611288) Escherichia coli str. K-12 substr. DH10B 6059240 YP_001733042.1 CDS fecD NC_010473.1 4611289 4612245 R Ferric citrate binds FecA and is transported across the outer membrane while transmits a signal across the cytoplasmic membrane protein FecR. FecR transmits a signal across the membrane and activates the cytoplasmic FecI that directs the RNA polymerase to express the fecABCDE operon (which encodes the ferric citrate outer membrane receptor and the ferric citrate ABC transporter), as well as fecIR. FecD is one of two (along with FecC) integral membrane protein components of the iron dicitrate ABC transporter.; iron-dicitrate transporter subunit FecD complement(4611289..4612245) Escherichia coli str. K-12 substr. DH10B 6059264 YP_001733043.1 CDS fecC NC_010473.1 4612242 4613240 R part of the FecBCDE citrate-dependent iron (III) transport system; iron-dicitrate transporter permease subunit complement(4612242..4613240) Escherichia coli str. K-12 substr. DH10B 6059279 YP_001733044.1 CDS fecB NC_010473.1 4613237 4614139 R part of the ABC transporter involved in the uptake of citrate-dependent Fe(3+); iron-dicitrate transporter substrate-binding subunit complement(4613237..4614139) Escherichia coli str. K-12 substr. DH10B 6061791 YP_001733045.1 CDS fecA NC_010473.1 4614184 4616508 R KpLE2 phage-like element; ferric citrate outer membrane transporter complement(4614184..4616508) Escherichia coli str. K-12 substr. DH10B 6059339 YP_001733046.1 CDS fecR NC_010473.1 4616595 4617548 R with FecA forms the FecAR signal transduction system; ferric citrate binds FecA and transmits a signal across the outer membrane to FecR. FecR transmits a signal across the cytoplasmic membrane and activates the sigma 70 protein FecI that directs the RNA polymerase to express the fecABCDE operon; fec operon regulator FecR complement(4616595..4617548) Escherichia coli str. K-12 substr. DH10B 6059305 YP_001733047.1 CDS fecI NC_010473.1 4617545 4618066 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor regulates the genes for iron dicitrate transport; RNA polymerase sigma factor FecI complement(4617545..4618066) Escherichia coli str. K-12 substr. DH10B 6061900 YP_001733048.1 CDS insA-7 NC_010473.1 4618358 4618633 D KpLE2 phage-like element; IS1 repressor protein InsA 4618358..4618633 Escherichia coli str. K-12 substr. DH10B 6059500 YP_001733049.1 CDS yjhU NC_010473.1 4619169 4620155 R KpLE2 phage-like element; DNA-binding transcriptional regulator complement(4619169..4620155) Escherichia coli str. K-12 substr. DH10B 6058186 YP_001733050.1 CDS yjhF NC_010473.1 4620502 4621851 R KpLE2 phage-like element; transporter complement(4620502..4621851) Escherichia coli str. K-12 substr. DH10B 6058765 YP_001733051.1 CDS yjhG NC_010473.1 4621958 4623925 R hypothetical protein complement(4621958..4623925) Escherichia coli str. K-12 substr. DH10B 6058776 YP_001733052.1 CDS yjhH NC_010473.1 4623936 4624841 R KpLE2 phage-like element; lyase/synthase complement(4623936..4624841) Escherichia coli str. K-12 substr. DH10B 6058800 YP_001733053.1 CDS yjhI NC_010473.1 4624846 4625634 R KpLE2 phage-like element; DNA-binding transcriptional regulator complement(4624846..4625634) Escherichia coli str. K-12 substr. DH10B 6058806 YP_001733054.1 CDS sgcR NC_010473.1 4625937 4626719 R KpLE2 phage-like element; DNA-binding transcriptional regulator complement(4625937..4626719) Escherichia coli str. K-12 substr. DH10B 6059442 YP_001733055.1 CDS sgcE NC_010473.1 4626736 4627368 R epimerase complement(4626736..4627368) Escherichia coli str. K-12 substr. DH10B 6059413 YP_001733056.1 CDS sgcA NC_010473.1 4627380 4627811 R KpLE2 phage-like element; phosphotransferase enzyme IIA component complement(4627380..4627811) Escherichia coli str. K-12 substr. DH10B 6059407 YP_001733057.1 CDS sgcQ NC_010473.1 4627942 4628748 R KpLE2 phage-like element; nucleoside triphosphatase complement(4627942..4628748) Escherichia coli str. K-12 substr. DH10B 6058858 YP_001733058.1 CDS sgcC NC_010473.1 4628761 4630074 R KpLE2 phage-like element; phosphotransferase enzyme IIC component complement(4628761..4630074) Escherichia coli str. K-12 substr. DH10B 6059456 YP_001733059.1 CDS sgcB NC_010473.1 4630086 4630364 R enzyme IIB component of PTS complement(4630086..4630364) Escherichia coli str. K-12 substr. DH10B 6059395 YP_001733060.1 CDS sgcX NC_010473.1 4630361 4631482 R KpLE2 phage-like element complement(4630361..4631482) Escherichia coli str. K-12 substr. DH10B 6059564 YP_001733061.1 CDS yjhP NC_010473.1 4632268 4633014 R KpLE2 phage-like element; methyltransferase complement(4632268..4633014) Escherichia coli str. K-12 substr. DH10B 6059527 YP_001733062.1 CDS yjhQ NC_010473.1 4633070 4633615 R KpLE2 phage-like element; acetyltransferase complement(4633070..4633615) Escherichia coli str. K-12 substr. DH10B 6059587 YP_001733063.1 CDS yjhX NC_010473.1 4633627 4633884 R hypothetical protein complement(4633627..4633884) Escherichia coli str. K-12 substr. DH10B 6059663 YP_001733064.1 CDS yjhS NC_010473.1 4636445 4637425 R hypothetical protein complement(4636445..4637425) Escherichia coli str. K-12 substr. DH10B 6058895 YP_001733065.1 CDS yjhT NC_010473.1 4637490 4638596 R N-acetylneuraminic acid mutarotase complement(4637490..4638596) Escherichia coli str. K-12 substr. DH10B 6058492 YP_001733066.1 CDS yjhA NC_010473.1 4638616 4639332 R N-acetylnuraminic acid outer membrane channel protein complement(4638616..4639332) Escherichia coli str. K-12 substr. DH10B 6059055 YP_001733067.1 CDS yjjA NC_010473.1 4644180 4644674 R hypothetical protein complement(4644180..4644674) Escherichia coli str. K-12 substr. DH10B 6058931 YP_001733068.1 CDS dnaC NC_010473.1 4644723 4645460 R acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC complement(4644723..4645460) Escherichia coli str. K-12 substr. DH10B 6059802 YP_001733069.1 CDS dnaT NC_010473.1 4645463 4646002 R This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI complement(4645463..4646002) Escherichia coli str. K-12 substr. DH10B 6059778 YP_001733070.2 CDS yjjB NC_010473.1 4646109 4646582 R hypothetical protein complement(4646109..4646582) Escherichia coli str. K-12 substr. DH10B 6059878 YP_001733071.1 CDS yjjP NC_010473.1 4646573 4647343 R inner membrane protein complement(4646573..4647343) Escherichia coli str. K-12 substr. DH10B 6060000 YP_001733072.1 CDS yjjQ NC_010473.1 4647962 4648687 D DNA-binding transcriptional regulator 4647962..4648687 Escherichia coli str. K-12 substr. DH10B 6060022 YP_001733073.1 CDS bglJ NC_010473.1 4648699 4649322 D regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 4648699..4649322 Escherichia coli str. K-12 substr. DH10B 6059792 YP_001733074.1 CDS fhuF NC_010473.1 4649360 4650148 R ferric hydroximate transport ferric iron reductase complement(4649360..4650148) Escherichia coli str. K-12 substr. DH10B 6060481 YP_001733075.1 CDS yjjZ NC_010473.1 4650289 4650525 D hypothetical protein 4650289..4650525 Escherichia coli str. K-12 substr. DH10B 6060115 YP_001733076.1 CDS rsmC NC_010473.1 4651154 4652185 R 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase complement(4651154..4652185) Escherichia coli str. K-12 substr. DH10B 6059966 YP_001733077.1 CDS holD NC_010473.1 4652288 4652701 D with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 4652288..4652701 Escherichia coli str. K-12 substr. DH10B 6060169 YP_001733078.1 CDS rimI NC_010473.1 4652670 4653116 D alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 4652670..4653116 Escherichia coli str. K-12 substr. DH10B 6060177 YP_001733079.1 CDS yjjG NC_010473.1 4653131 4653808 D manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 4653131..4653808 Escherichia coli str. K-12 substr. DH10B 6059754 YP_001733080.1 CDS prfC NC_010473.1 4653899 4655488 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 4653899..4655488 Escherichia coli str. K-12 substr. DH10B 6060201 YP_001733081.1 CDS osmY NC_010473.1 4655881 4656486 D hypothetical protein 4655881..4656486 Escherichia coli str. K-12 substr. DH10B 6060240 YP_001733082.1 CDS ytjA NC_010473.1 4656595 4656774 D hypothetical protein 4656595..4656774 Escherichia coli str. K-12 substr. DH10B 6060244 YP_001733083.1 CDS yjjU NC_010473.1 4656896 4657969 D esterase 4656896..4657969 Escherichia coli str. K-12 substr. DH10B 6060263 YP_001733084.1 CDS yjjV NC_010473.1 4657966 4658745 D putative deoxyribonuclease YjjV 4657966..4658745 Escherichia coli str. K-12 substr. DH10B 6059351 YP_001733085.1 CDS yjjW NC_010473.1 4659165 4660028 R pyruvate formate lyase activating enzyme complement(4659165..4660028) Escherichia coli str. K-12 substr. DH10B 6060262 YP_001733086.1 CDS yjjI NC_010473.1 4660000 4661550 R hypothetical protein complement(4660000..4661550) Escherichia coli str. K-12 substr. DH10B 6060286 YP_001733087.1 CDS deoC NC_010473.1 4661808 4662587 D catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 4661808..4662587 Escherichia coli str. K-12 substr. DH10B 6060343 YP_001733088.1 CDS deoA NC_010473.1 4662714 4664036 D Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 4662714..4664036 Escherichia coli str. K-12 substr. DH10B 6060363 YP_001733089.1 CDS deoB NC_010473.1 4664088 4665311 D catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 4664088..4665311 Escherichia coli str. K-12 substr. DH10B 6060377 YP_001733090.1 CDS deoD NC_010473.1 4665368 4666087 D catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 4665368..4666087 Escherichia coli str. K-12 substr. DH10B 6058701 YP_001733091.1 CDS yjjJ NC_010473.1 4666254 4667585 D hypothetical protein 4666254..4667585 Escherichia coli str. K-12 substr. DH10B 6058313 YP_001733092.1 CDS lplA NC_010473.1 4667586 4668602 R Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A complement(4667586..4668602) Escherichia coli str. K-12 substr. DH10B 6060411 YP_001733093.1 CDS ytjB NC_010473.1 4668630 4669274 R hypothetical protein complement(4668630..4669274) Escherichia coli str. K-12 substr. DH10B 6060419 YP_001733094.1 CDS serB NC_010473.1 4669380 4670348 D catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 4669380..4670348 Escherichia coli str. K-12 substr. DH10B 6058202 YP_001733095.1 CDS radA NC_010473.1 4670397 4671779 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 4670397..4671779 Escherichia coli str. K-12 substr. DH10B 6060422 YP_001733096.1 CDS nadR NC_010473.1 4671800 4673032 D catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 4671800..4673032 Escherichia coli str. K-12 substr. DH10B 6060431 YP_001733097.1 CDS yjjK NC_010473.1 4673340 4675007 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein complement(4673340..4675007) Escherichia coli str. K-12 substr. DH10B 6060436 YP_001733098.1 CDS slt NC_010473.1 4675218 4677155 D catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 4675218..4677155 Escherichia coli str. K-12 substr. DH10B 6059751 YP_001733099.1 CDS trpR NC_010473.1 4677245 4677571 D When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 4677245..4677571 Escherichia coli str. K-12 substr. DH10B 6062195 YP_001733100.1 CDS yjjX NC_010473.1 4677718 4678230 R pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase complement(4677718..4678230) Escherichia coli str. K-12 substr. DH10B 6059301 YP_001733101.1 CDS ytjC NC_010473.1 4678282 4678929 D catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 4678282..4678929 Escherichia coli str. K-12 substr. DH10B 6058703 YP_001733102.1 CDS rob NC_010473.1 4678926 4679795 R DNA-binding transcriptional activator complement(4678926..4679795) Escherichia coli str. K-12 substr. DH10B 6061772 YP_001733103.1 CDS creA NC_010473.1 4680006 4680479 D hypothetical protein 4680006..4680479 Escherichia coli str. K-12 substr. DH10B 6061351 YP_001733104.1 CDS creB NC_010473.1 4680492 4681181 D response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 4680492..4681181 Escherichia coli str. K-12 substr. DH10B 6059119 YP_001733105.1 CDS creC NC_010473.1 4681181 4682605 D part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 4681181..4682605 Escherichia coli str. K-12 substr. DH10B 6062403 YP_001733106.1 CDS creD NC_010473.1 4682663 4684015 D hypothetical protein 4682663..4684015 Escherichia coli str. K-12 substr. DH10B 6062034 YP_001733107.1 CDS arcA NC_010473.1 4684075 4684791 R two-component response regulator complement(4684075..4684791) Escherichia coli str. K-12 substr. DH10B 6060398 YP_001733108.1 CDS yjjY NC_010473.1 4684887 4685027 D hypothetical protein 4684887..4685027 Escherichia coli str. K-12 substr. DH10B 6060432 YP_001733109.1 CDS yjtD NC_010473.1 4685427 4686113 D member of the SPOUT superfamily of methyltransferases; putative RNA methyltransferase 4685427..4686113 Escherichia coli str. K-12 substr. DH10B 6060413 ECDH10B_0183 tRNA ileV NC_010473.1 199485 199561 D tRNA-Ile 199485..199561 Escherichia coli str. K-12 substr. DH10B 6058195 ECDH10B_0184 tRNA alaV NC_010473.1 199604 199679 D tRNA-Ala 199604..199679 Escherichia coli str. K-12 substr. DH10B 6058203 ECDH10B_0187 tRNA aspU NC_010473.1 203032 203108 D tRNA-Asp 203032..203108 Escherichia coli str. K-12 substr. DH10B 6058497 ECDH10B_0197 tRNA aspV NC_010473.1 211035 211111 D tRNA-Asp 211035..211111 Escherichia coli str. K-12 substr. DH10B 6061084 ECDH10B_0226 tRNA thrW NC_010473.1 236199 236274 D tRNA-Thr 236199..236274 Escherichia coli str. K-12 substr. DH10B 6062102 ECDH10B_0492 tRNA argU NC_010473.1 503278 503354 D tRNA-Arg 503278..503354 Escherichia coli str. K-12 substr. DH10B 6060121 ECDH10B_0732 tRNA glnX NC_010473.1 748245 748319 R tRNA-Gln complement(748245..748319) Escherichia coli str. K-12 substr. DH10B 6061474 ECDH10B_0733 tRNA glnV NC_010473.1 748357 748431 R tRNA-Gln complement(748357..748431) Escherichia coli str. K-12 substr. DH10B 6062064 ECDH10B_0734 tRNA metU NC_010473.1 748479 748555 R tRNA-Met complement(748479..748555) Escherichia coli str. K-12 substr. DH10B 6061372 ECDH10B_0735 tRNA glnW NC_010473.1 748571 748645 R tRNA-Gln complement(748571..748645) Escherichia coli str. K-12 substr. DH10B 6062374 ECDH10B_0736 tRNA glnU NC_010473.1 748680 748754 R tRNA-Gln complement(748680..748754) Escherichia coli str. K-12 substr. DH10B 6061369 ECDH10B_0737 tRNA leuW NC_010473.1 748778 748862 R tRNA-Leu complement(748778..748862) Escherichia coli str. K-12 substr. DH10B 6061983 ECDH10B_0738 tRNA metT NC_010473.1 748872 748948 R tRNA-Met complement(748872..748948) Escherichia coli str. K-12 substr. DH10B 6059385 ECDH10B_0810 tRNA lysT NC_010473.1 832369 832444 D tRNA-Lys 832369..832444 Escherichia coli str. K-12 substr. DH10B 6061243 ECDH10B_0811 tRNA valT NC_010473.1 832580 832655 D tRNA-Val 832580..832655 Escherichia coli str. K-12 substr. DH10B 6059146 ECDH10B_0812 tRNA lysW NC_010473.1 832658 832733 D tRNA-Lys 832658..832733 Escherichia coli str. K-12 substr. DH10B 6060735 ECDH10B_0813 tRNA valZ NC_010473.1 832883 832958 D tRNA-Val 832883..832958 Escherichia coli str. K-12 substr. DH10B 6062250 ECDH10B_0814 tRNA lysY NC_010473.1 832962 833037 D tRNA-Lys 832962..833037 Escherichia coli str. K-12 substr. DH10B 6061755 ECDH10B_0815 tRNA lysZ NC_010473.1 833184 833259 D tRNA-Lys 833184..833259 Escherichia coli str. K-12 substr. DH10B 6061085 ECDH10B_0816 tRNA lysQ NC_010473.1 833392 833467 D tRNA-Lys 833392..833467 Escherichia coli str. K-12 substr. DH10B 6061331 ECDH10B_0953 tRNA serW NC_010473.1 979035 979122 R tRNA-Ser complement(979035..979122) Escherichia coli str. K-12 substr. DH10B 6060749 ECDH10B_1041 tRNA serT NC_010473.1 1084776 1084863 R tRNA-Ser complement(1084776..1084863) Escherichia coli str. K-12 substr. DH10B 6060316 ECDH10B_1104 tRNA serX NC_010473.1 1152233 1152320 R tRNA-Ser complement(1152233..1152320) Escherichia coli str. K-12 substr. DH10B 6059402 ECDH10B_1290 tRNA tyrV NC_010473.1 1326708 1326792 R tRNA-Tyr complement(1326708..1326792) Escherichia coli str. K-12 substr. DH10B 6058439 ECDH10B_1291 tRNA tyrT NC_010473.1 1327002 1327086 R tRNA-Tyr complement(1327002..1327086) Escherichia coli str. K-12 substr. DH10B 6059306 ECDH10B_1799 tRNA valV NC_010473.1 1835030 1835106 D tRNA-Val 1835030..1835106 Escherichia coli str. K-12 substr. DH10B 6062091 ECDH10B_1800 tRNA valW NC_010473.1 1835111 1835187 D tRNA-Val 1835111..1835187 Escherichia coli str. K-12 substr. DH10B 6061694 ECDH10B_2050 tRNA leuZ NC_010473.1 2080847 2080933 R tRNA-Leu complement(2080847..2080933) Escherichia coli str. K-12 substr. DH10B 6058720 ECDH10B_2051 tRNA cysT NC_010473.1 2080946 2081019 R tRNA-Cys complement(2080946..2081019) Escherichia coli str. K-12 substr. DH10B 6062356 ECDH10B_2052 tRNA glyW NC_010473.1 2081074 2081149 R tRNA-Gly complement(2081074..2081149) Escherichia coli str. K-12 substr. DH10B 6062368 ECDH10B_2118 tRNA serU NC_010473.1 2132500 2132589 R tRNA-Ser complement(2132500..2132589) Escherichia coli str. K-12 substr. DH10B 6059169 ECDH10B_2120 tRNA asnT NC_010473.1 2133581 2133656 D tRNA-Asn 2133581..2133656 Escherichia coli str. K-12 substr. DH10B 6059172 ECDH10B_2128 tRNA asnW NC_010473.1 2147059 2147134 R tRNA-Asn complement(2147059..2147134) Escherichia coli str. K-12 substr. DH10B 6059216 ECDH10B_2130 tRNA asnU NC_010473.1 2148883 2148958 D tRNA-Asn 2148883..2148958 Escherichia coli str. K-12 substr. DH10B 6059221 ECDH10B_2133 tRNA asnV NC_010473.1 2151292 2151367 D tRNA-Asn 2151292..2151367 Escherichia coli str. K-12 substr. DH10B 6059226 ECDH10B_2347 tRNA proL NC_010473.1 2375221 2375297 D tRNA-Pro 2375221..2375297 Escherichia coli str. K-12 substr. DH10B 6060750 ECDH10B_2511 tRNA argW NC_010473.1 2556096 2556170 D tRNA-Arg 2556096..2556170 Escherichia coli str. K-12 substr. DH10B 6059919 ECDH10B_2560 tRNA alaX NC_010473.1 2607828 2607903 R tRNA-Ala complement(2607828..2607903) Escherichia coli str. K-12 substr. DH10B 6059990 ECDH10B_2561 tRNA alaW NC_010473.1 2607943 2608018 R tRNA-Ala complement(2607943..2608018) Escherichia coli str. K-12 substr. DH10B 6058326 ECDH10B_2565 tRNA valU NC_010473.1 2610718 2610793 D tRNA-Val 2610718..2610793 Escherichia coli str. K-12 substr. DH10B 6059995 ECDH10B_2566 tRNA valX NC_010473.1 2610838 2610913 D tRNA-Val 2610838..2610913 Escherichia coli str. K-12 substr. DH10B 6059988 ECDH10B_2567 tRNA valY NC_010473.1 2610960 2611035 D tRNA-Val 2610960..2611035 Escherichia coli str. K-12 substr. DH10B 6060153 ECDH10B_2568 tRNA lysV NC_010473.1 2611040 2611115 D tRNA-Lys 2611040..2611115 Escherichia coli str. K-12 substr. DH10B 6058591 ECDH10B_2758 tRNA gltW NC_010473.1 2819156 2819231 R tRNA-Glu complement(2819156..2819231) Escherichia coli str. K-12 substr. DH10B 6059839 ECDH10B_2820 tRNA ileY NC_010473.1 2875549 2875624 R tRNA-Ile complement(2875549..2875624) Escherichia coli str. K-12 substr. DH10B 6061881 ECDH10B_2859 tRNA argQ NC_010473.1 2908348 2908424 R tRNA-Arg complement(2908348..2908424) Escherichia coli str. K-12 substr. DH10B 6061242 ECDH10B_2860 tRNA argZ NC_010473.1 2908623 2908699 R tRNA-Arg complement(2908623..2908699) Escherichia coli str. K-12 substr. DH10B 6058335 ECDH10B_2861 tRNA argY NC_010473.1 2908762 2908838 R tRNA-Arg complement(2908762..2908838) Escherichia coli str. K-12 substr. DH10B 6058224 ECDH10B_2862 tRNA argV NC_010473.1 2909037 2909113 R tRNA-Arg complement(2909037..2909113) Escherichia coli str. K-12 substr. DH10B 6058205 ECDH10B_2863 tRNA serV NC_010473.1 2909117 2909209 R tRNA-Ser complement(2909117..2909209) Escherichia coli str. K-12 substr. DH10B 6060498 ECDH10B_2984 tRNA metZ NC_010473.1 3039279 3039355 D tRNA-Met 3039279..3039355 Escherichia coli str. K-12 substr. DH10B 6061928 ECDH10B_2985 tRNA metW NC_010473.1 3039389 3039465 D tRNA-Met 3039389..3039465 Escherichia coli str. K-12 substr. DH10B 6061386 ECDH10B_2986 tRNA metV NC_010473.1 3039499 3039575 D tRNA-Met 3039499..3039575 Escherichia coli str. K-12 substr. DH10B 6061299 ECDH10B_3039 tRNA glyU NC_010473.1 3090876 3090949 R tRNA-Gly complement(3090876..3090949) Escherichia coli str. K-12 substr. DH10B 6061228 ECDH10B_3146 tRNA pheV NC_010473.1 3207856 3207931 R tRNA-Phe complement(3207856..3207931) Escherichia coli str. K-12 substr. DH10B 6060207 ECDH10B_3244 tRNA ileX NC_010473.1 3311365 3311440 D tRNA-Ile 3311365..3311440 Escherichia coli str. K-12 substr. DH10B 6058784 ECDH10B_3345 tRNA metY NC_010473.1 3413980 3414056 R tRNA-Met complement(3413980..3414056) Escherichia coli str. K-12 substr. DH10B 6060194 ECDH10B_3348 tRNA leuU NC_010473.1 3417839 3417925 R tRNA-Leu complement(3417839..3417925) Escherichia coli str. K-12 substr. DH10B 6060123 ECDH10B_3448 tRNA thrV NC_010473.1 3519347 3519422 R tRNA-Thr complement(3519347..3519422) Escherichia coli str. K-12 substr. DH10B 6058684 ECDH10B_3451 tRNA alaU NC_010473.1 3522725 3522800 R tRNA-Ala complement(3522725..3522800) Escherichia coli str. K-12 substr. DH10B 6060141 ECDH10B_3452 tRNA ileU NC_010473.1 3522843 3522919 R tRNA-Ile complement(3522843..3522919) Escherichia coli str. K-12 substr. DH10B 6058802 ECDH10B_3724 tRNA proK NC_010473.1 3804216 3804292 R tRNA-Pro complement(3804216..3804292) Escherichia coli str. K-12 substr. DH10B 6058683 ECDH10B_3840 tRNA selC NC_010473.1 3931829 3931923 D tRNA-Sec 3931829..3931923 Escherichia coli str. K-12 substr. DH10B 6058595 ECDH10B_3946 tRNA gltU NC_010473.1 4040378 4040453 D tRNA-Glu 4040378..4040453 Escherichia coli str. K-12 substr. DH10B 6058708 ECDH10B_3949 tRNA aspT NC_010473.1 4043815 4043891 D tRNA-Asp 4043815..4043891 Escherichia coli str. K-12 substr. DH10B 6059753 ECDH10B_3950 tRNA trpT NC_010473.1 4043900 4043975 D tRNA-Trp 4043900..4043975 Escherichia coli str. K-12 substr. DH10B 6060493 ECDH10B_3986 tRNA argX NC_010473.1 4079318 4079394 D tRNA-Arg 4079318..4079394 Escherichia coli str. K-12 substr. DH10B 6062045 ECDH10B_3987 tRNA hisR NC_010473.1 4079452 4079528 D tRNA-His 4079452..4079528 Escherichia coli str. K-12 substr. DH10B 6061139 ECDH10B_3988 tRNA leuT NC_010473.1 4079549 4079635 D tRNA-Leu 4079549..4079635 Escherichia coli str. K-12 substr. DH10B 6061241 ECDH10B_3989 tRNA proM NC_010473.1 4079678 4079754 D tRNA-Pro 4079678..4079754 Escherichia coli str. K-12 substr. DH10B 6061271 ECDH10B_4041 tRNA ileT NC_010473.1 4134084 4134160 D tRNA-Ile 4134084..4134160 Escherichia coli str. K-12 substr. DH10B 6060760 ECDH10B_4042 tRNA alaT NC_010473.1 4134203 4134278 D tRNA-Ala 4134203..4134278 Escherichia coli str. K-12 substr. DH10B 6061585 ECDH10B_4158 tRNA gltT NC_010473.1 4266092 4266167 D tRNA-Glu 4266092..4266167 Escherichia coli str. K-12 substr. DH10B 6062057 ECDH10B_4164 tRNA thrU NC_010473.1 4273107 4273182 D tRNA-Thr 4273107..4273182 Escherichia coli str. K-12 substr. DH10B 6059832 ECDH10B_4165 tRNA tyrU NC_010473.1 4273191 4273275 D tRNA-Tyr 4273191..4273275 Escherichia coli str. K-12 substr. DH10B 6061397 ECDH10B_4166 tRNA glyT NC_010473.1 4273392 4273466 D tRNA-Gly 4273392..4273466 Escherichia coli str. K-12 substr. DH10B 6061672 ECDH10B_4167 tRNA thrT NC_010473.1 4273473 4273548 D tRNA-Thr 4273473..4273548 Escherichia coli str. K-12 substr. DH10B 6061912 ECDH10B_4197 tRNA gltV NC_010473.1 4307493 4307568 D tRNA-Glu 4307493..4307568 Escherichia coli str. K-12 substr. DH10B 6059536 ECDH10B_4327 tRNA pheU NC_010473.1 4460936 4461011 R tRNA-Phe complement(4460936..4461011) Escherichia coli str. K-12 substr. DH10B 6061710 ECDH10B_4358 tRNA glyV NC_010473.1 4490745 4490820 D tRNA-Gly 4490745..4490820 Escherichia coli str. K-12 substr. DH10B 6060292 ECDH10B_4359 tRNA glyX NC_010473.1 4490857 4490932 D tRNA-Gly 4490857..4490932 Escherichia coli str. K-12 substr. DH10B 6059716 ECDH10B_4360 tRNA glyY NC_010473.1 4490968 4491043 D tRNA-Gly 4490968..4491043 Escherichia coli str. K-12 substr. DH10B 6059775 ECDH10B_4463 tRNA leuX NC_010473.1 4596236 4596320 D tRNA-Leu 4596236..4596320 Escherichia coli str. K-12 substr. DH10B 6059054 ECDH10B_4525 tRNA leuV NC_010473.1 4650564 4650650 R tRNA-Leu complement(4650564..4650650) Escherichia coli str. K-12 substr. DH10B 6060154 ECDH10B_4526 tRNA leuP NC_010473.1 4650685 4650771 R tRNA-Leu complement(4650685..4650771) Escherichia coli str. K-12 substr. DH10B 6059569 ECDH10B_4527 tRNA leuQ NC_010473.1 4650800 4650886 R tRNA-Leu complement(4650800..4650886) Escherichia coli str. K-12 substr. DH10B 6059444 ECDH10B_0182 rRNA rrsH NC_010473.1 197875 199416 D 16S ribosomal RNA 197875..199416 Escherichia coli str. K-12 substr. DH10B 6062217 ECDH10B_0185 rRNA rrlH NC_010473.1 199863 202766 D 23S ribosomal RNA 199863..202766 Escherichia coli str. K-12 substr. DH10B 6058536 ECDH10B_0186 rRNA rrfH NC_010473.1 202860 202979 D 5S ribosomal RNA 202860..202979 Escherichia coli str. K-12 substr. DH10B 6059787 ECDH10B_2756 rRNA rrfG NC_010473.1 2815856 2815975 R 5S ribosomal RNA complement(2815856..2815975) Escherichia coli str. K-12 substr. DH10B 6060783 ECDH10B_2757 rRNA rrlG NC_010473.1 2816068 2818971 R 23S ribosomal RNA complement(2816068..2818971) Escherichia coli str. K-12 substr. DH10B 6058172 ECDH10B_2759 rRNA rrsG NC_010473.1 2819403 2820944 R 16S ribosomal RNA complement(2819403..2820944) Escherichia coli str. K-12 substr. DH10B 6060053 ECDH10B_3447 rRNA rrfF NC_010473.1 3519190 3519309 R 5S ribosomal RNA complement(3519190..3519309) Escherichia coli str. K-12 substr. DH10B 6058680 ECDH10B_3449 rRNA rrfD NC_010473.1 3519435 3519554 R 5S ribosomal RNA complement(3519435..3519554) Escherichia coli str. K-12 substr. DH10B 6059634 ECDH10B_3450 rRNA rrlD NC_010473.1 3519647 3522550 R 23S ribosomal RNA complement(3519647..3522550) Escherichia coli str. K-12 substr. DH10B 6060186 ECDH10B_3453 rRNA rrsD NC_010473.1 3522988 3524529 R 16S ribosomal RNA complement(3522988..3524529) Escherichia coli str. K-12 substr. DH10B 6059497 ECDH10B_3945 rRNA rrsC NC_010473.1 4038751 4040292 D 16S ribosomal RNA 4038751..4040292 Escherichia coli str. K-12 substr. DH10B 6060837 ECDH10B_3947 rRNA rrlC NC_010473.1 4040647 4043550 D 23S ribosomal RNA 4040647..4043550 Escherichia coli str. K-12 substr. DH10B 6058666 ECDH10B_3948 rRNA rrfC NC_010473.1 4043643 4043762 D 5S ribosomal RNA 4043643..4043762 Escherichia coli str. K-12 substr. DH10B 6058637 ECDH10B_4040 rRNA rrsA NC_010473.1 4132474 4134015 D 16S ribosomal RNA 4132474..4134015 Escherichia coli str. K-12 substr. DH10B 6060893 ECDH10B_4043 rRNA rrlA NC_010473.1 4134462 4137366 D 23S ribosomal RNA 4134462..4137366 Escherichia coli str. K-12 substr. DH10B 6060789 ECDH10B_4044 rRNA rrfA NC_010473.1 4137460 4137579 D 5S ribosomal RNA 4137460..4137579 Escherichia coli str. K-12 substr. DH10B 6061733 ECDH10B_4157 rRNA rrsB NC_010473.1 4264379 4265920 D 16S ribosomal RNA 4264379..4265920 Escherichia coli str. K-12 substr. DH10B 6060074 ECDH10B_4159 rRNA rrlB NC_010473.1 4266361 4269264 D 23S ribosomal RNA 4266361..4269264 Escherichia coli str. K-12 substr. DH10B 6060674 ECDH10B_4160 rRNA rrfB NC_010473.1 4269357 4269476 D 5S ribosomal RNA 4269357..4269476 Escherichia coli str. K-12 substr. DH10B 6060881 ECDH10B_4196 rRNA rrsE NC_010473.1 4305866 4307407 D 16S ribosomal RNA 4305866..4307407 Escherichia coli str. K-12 substr. DH10B 6059263 ECDH10B_4198 rRNA rrlE NC_010473.1 4307762 4310665 D 23S ribosomal RNA 4307762..4310665 Escherichia coli str. K-12 substr. DH10B 6059597 ECDH10B_4199 rRNA rrfE NC_010473.1 4310759 4310878 D 5S ribosomal RNA 4310759..4310878 Escherichia coli str. K-12 substr. DH10B 6059613